LOCUS       DBBGSP010000001       113718 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000001 DBBGSP010000000
VERSION     DBBGSP010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 113718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 113718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..113718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.001"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(290..1087)
                     /locus_tag="ACIZE9_000001"
     CDS             complement(290..1087)
                     /locus_tag="ACIZE9_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HGC6091904.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(1084..2268)
                     /locus_tag="ACIZE9_000002"
     CDS             complement(1084..2268)
                     /locus_tag="ACIZE9_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HGC6091905.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(2293..3540)
                     /locus_tag="ACIZE9_000003"
     CDS             complement(2293..3540)
                     /locus_tag="ACIZE9_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGC6091906.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            3755..5500
                     /gene="dnaX"
                     /locus_tag="ACIZE9_000004"
     CDS             3755..5500
                     /gene="dnaX"
                     /locus_tag="ACIZE9_000004"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGC6091907.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            5520..5834
                     /locus_tag="ACIZE9_000005"
     CDS             5520..5834
                     /locus_tag="ACIZE9_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGC6091908.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            5859..6455
                     /gene="recR"
                     /locus_tag="ACIZE9_000006"
     CDS             5859..6455
                     /gene="recR"
                     /locus_tag="ACIZE9_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGC6091909.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            6519..7163
                     /gene="tmk"
                     /locus_tag="ACIZE9_000007"
     CDS             6519..7163
                     /gene="tmk"
                     /locus_tag="ACIZE9_000007"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGC6091910.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            7178..7507
                     /locus_tag="ACIZE9_000008"
     CDS             7178..7507
                     /locus_tag="ACIZE9_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HGC6091911.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            7521..8459
                     /gene="holB"
                     /locus_tag="ACIZE9_000009"
     CDS             7521..8459
                     /gene="holB"
                     /locus_tag="ACIZE9_000009"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGC6091912.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            8495..9319
                     /locus_tag="ACIZE9_000010"
     CDS             8495..9319
                     /locus_tag="ACIZE9_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HGC6091913.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            9312..9659
                     /locus_tag="ACIZE9_000011"
     CDS             9312..9659
                     /locus_tag="ACIZE9_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGC6091914.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            9728..10600
                     /gene="rsmI"
                     /locus_tag="ACIZE9_000012"
     CDS             9728..10600
                     /gene="rsmI"
                     /locus_tag="ACIZE9_000012"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGC6091915.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            10709..11830
                     /gene="dinB"
                     /locus_tag="ACIZE9_000013"
     CDS             10709..11830
                     /gene="dinB"
                     /locus_tag="ACIZE9_000013"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGC6091916.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(11884..12486)
                     /gene="nrdG"
                     /locus_tag="ACIZE9_000014"
     CDS             complement(11884..12486)
                     /gene="nrdG"
                     /locus_tag="ACIZE9_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGC6091917.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(12801..14990)
                     /gene="nrdD"
                     /locus_tag="ACIZE9_000015"
     CDS             complement(12801..14990)
                     /gene="nrdD"
                     /locus_tag="ACIZE9_000015"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGC6091918.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            15316..16083
                     /locus_tag="ACIZE9_000016"
     CDS             15316..16083
                     /locus_tag="ACIZE9_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6091919.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            16073..18115
                     /locus_tag="ACIZE9_000017"
     CDS             16073..18115
                     /locus_tag="ACIZE9_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6091920.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            18396..18545
                     /locus_tag="ACIZE9_000018"
     CDS             18396..18545
                     /locus_tag="ACIZE9_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGC6091921.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            18556..20070
                     /gene="dltA"
                     /locus_tag="ACIZE9_000019"
     CDS             18556..20070
                     /gene="dltA"
                     /locus_tag="ACIZE9_000019"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGC6091922.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            20067..21272
                     /gene="dltB"
                     /locus_tag="ACIZE9_000020"
     CDS             20067..21272
                     /gene="dltB"
                     /locus_tag="ACIZE9_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGC6091923.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            21317..21550
                     /gene="dltC"
                     /locus_tag="ACIZE9_000021"
     CDS             21317..21550
                     /gene="dltC"
                     /locus_tag="ACIZE9_000021"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGC6091924.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            21553..22821
                     /gene="dltD"
                     /locus_tag="ACIZE9_000022"
     CDS             21553..22821
                     /gene="dltD"
                     /locus_tag="ACIZE9_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGC6091925.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            22962..24044
                     /locus_tag="ACIZE9_000023"
     CDS             22962..24044
                     /locus_tag="ACIZE9_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGC6091926.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            24044..24847
                     /locus_tag="ACIZE9_000024"
     CDS             24044..24847
                     /locus_tag="ACIZE9_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGC6091927.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            24917..25657
                     /locus_tag="ACIZE9_000025"
     CDS             24917..25657
                     /locus_tag="ACIZE9_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGC6091928.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            25668..26672
                     /locus_tag="ACIZE9_000026"
     CDS             25668..26672
                     /locus_tag="ACIZE9_000026"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGC6091929.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(26717..28561)
                     /locus_tag="ACIZE9_000027"
     CDS             complement(26717..28561)
                     /locus_tag="ACIZE9_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6091930.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            28772..29290
                     /locus_tag="ACIZE9_000028"
     CDS             28772..29290
                     /locus_tag="ACIZE9_000028"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGC6091931.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            29418..30101
                     /locus_tag="ACIZE9_000029"
     CDS             29418..30101
                     /locus_tag="ACIZE9_000029"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGC6091932.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            30410..30483
                     /locus_tag="ACIZE9_000030"
     tRNA            30410..30483
                     /locus_tag="ACIZE9_000030"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30444..30446,aa:Arg,seq:tct)
     gene            30642..31001
                     /locus_tag="ACIZE9_000031"
     CDS             30642..31001
                     /locus_tag="ACIZE9_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGC6091933.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            31124..32755
                     /locus_tag="ACIZE9_000032"
     CDS             31124..32755
                     /locus_tag="ACIZE9_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HGC6091934.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQFPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(32817..33458)
                     /locus_tag="ACIZE9_000033"
     CDS             complement(32817..33458)
                     /locus_tag="ACIZE9_000033"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGC6091935.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    33644..33720
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            33740..34048
                     /gene="rplU"
                     /locus_tag="ACIZE9_000034"
     CDS             33740..34048
                     /gene="rplU"
                     /locus_tag="ACIZE9_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGC6091936.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            34075..34419
                     /locus_tag="ACIZE9_000035"
     CDS             34075..34419
                     /locus_tag="ACIZE9_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGC6091937.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            34432..34725
                     /gene="rpmA"
                     /locus_tag="ACIZE9_000036"
     CDS             34432..34725
                     /gene="rpmA"
                     /locus_tag="ACIZE9_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGC6091938.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            35159..37966
                     /locus_tag="ACIZE9_000037"
     CDS             35159..37966
                     /locus_tag="ACIZE9_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC6091939.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            38157..38648
                     /locus_tag="ACIZE9_000038"
     CDS             38157..38648
                     /locus_tag="ACIZE9_000038"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HGC6091940.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            38751..39740
                     /locus_tag="ACIZE9_000039"
     CDS             38751..39740
                     /locus_tag="ACIZE9_000039"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HGC6091941.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            39773..40576
                     /locus_tag="ACIZE9_000040"
     CDS             39773..40576
                     /locus_tag="ACIZE9_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGC6091942.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            40597..41511
                     /locus_tag="ACIZE9_000041"
     CDS             40597..41511
                     /locus_tag="ACIZE9_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC6091943.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            41594..41968
                     /locus_tag="ACIZE9_000042"
     CDS             41594..41968
                     /locus_tag="ACIZE9_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGC6091944.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            42107..42352
                     /locus_tag="ACIZE9_000043"
     CDS             42107..42352
                     /locus_tag="ACIZE9_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGC6091945.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            42524..43588
                     /locus_tag="ACIZE9_000044"
     CDS             42524..43588
                     /locus_tag="ACIZE9_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGC6091946.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            43834..44259
                     /locus_tag="ACIZE9_000045"
     CDS             43834..44259
                     /locus_tag="ACIZE9_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGC6091947.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            44252..44701
                     /gene="nusB"
                     /locus_tag="ACIZE9_000046"
     CDS             44252..44701
                     /gene="nusB"
                     /locus_tag="ACIZE9_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGC6091948.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            44798..45652
                     /locus_tag="ACIZE9_000047"
     CDS             44798..45652
                     /locus_tag="ACIZE9_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGC6091949.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            45653..46990
                     /gene="xseA"
                     /locus_tag="ACIZE9_000048"
     CDS             45653..46990
                     /gene="xseA"
                     /locus_tag="ACIZE9_000048"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGC6091950.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            46995..47219
                     /locus_tag="ACIZE9_000049"
     CDS             46995..47219
                     /locus_tag="ACIZE9_000049"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGC6091951.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            47221..48111
                     /locus_tag="ACIZE9_000050"
     CDS             47221..48111
                     /locus_tag="ACIZE9_000050"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGC6091952.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            48120..48938
                     /locus_tag="ACIZE9_000051"
     CDS             48120..48938
                     /locus_tag="ACIZE9_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGC6091953.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            49045..49494
                     /locus_tag="ACIZE9_000052"
     CDS             49045..49494
                     /locus_tag="ACIZE9_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGC6091954.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            49512..51194
                     /gene="recN"
                     /locus_tag="ACIZE9_000053"
     CDS             49512..51194
                     /gene="recN"
                     /locus_tag="ACIZE9_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGC6091955.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(51249..51365)
                     /locus_tag="ACIZE9_000054"
     CDS             complement(51249..51365)
                     /locus_tag="ACIZE9_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGC6091956.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(51438..52394)
                     /locus_tag="ACIZE9_000055"
     CDS             complement(51438..52394)
                     /locus_tag="ACIZE9_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGC6091957.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            52565..52933
                     /locus_tag="ACIZE9_000056"
     CDS             52565..52933
                     /locus_tag="ACIZE9_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGC6091958.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            53103..53534
                     /gene="mraZ"
                     /locus_tag="ACIZE9_000057"
     CDS             53103..53534
                     /gene="mraZ"
                     /locus_tag="ACIZE9_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HGC6091959.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            53555..54514
                     /gene="rsmH"
                     /locus_tag="ACIZE9_000058"
     CDS             53555..54514
                     /gene="rsmH"
                     /locus_tag="ACIZE9_000058"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGC6091960.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            54519..54920
                     /gene="ftsL"
                     /locus_tag="ACIZE9_000059"
     CDS             54519..54920
                     /gene="ftsL"
                     /locus_tag="ACIZE9_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGC6091961.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            54921..57113
                     /locus_tag="ACIZE9_000060"
     CDS             54921..57113
                     /locus_tag="ACIZE9_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HGC6091962.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            57139..58101
                     /gene="mraY"
                     /locus_tag="ACIZE9_000061"
     CDS             57139..58101
                     /gene="mraY"
                     /locus_tag="ACIZE9_000061"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGC6091963.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            58115..59476
                     /gene="murD"
                     /locus_tag="ACIZE9_000062"
     CDS             58115..59476
                     /gene="murD"
                     /locus_tag="ACIZE9_000062"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGC6091964.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            59502..60590
                     /gene="murG"
                     /locus_tag="ACIZE9_000063"
     CDS             59502..60590
                     /gene="murG"
                     /locus_tag="ACIZE9_000063"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HGC6091965.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            60605..61825
                     /locus_tag="ACIZE9_000064"
     CDS             60605..61825
                     /locus_tag="ACIZE9_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HGC6091966.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            61981..63306
                     /gene="ftsA"
                     /locus_tag="ACIZE9_000065"
     CDS             61981..63306
                     /gene="ftsA"
                     /locus_tag="ACIZE9_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGC6091967.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            63329..64570
                     /gene="ftsZ"
                     /locus_tag="ACIZE9_000066"
     CDS             63329..64570
                     /gene="ftsZ"
                     /locus_tag="ACIZE9_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGC6091968.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            64587..65264
                     /locus_tag="ACIZE9_000067"
     CDS             64587..65264
                     /locus_tag="ACIZE9_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGC6091969.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            65278..65877
                     /locus_tag="ACIZE9_000068"
     CDS             65278..65877
                     /locus_tag="ACIZE9_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGC6091970.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            65958..66179
                     /locus_tag="ACIZE9_000069"
     CDS             65958..66179
                     /locus_tag="ACIZE9_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGC6091971.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            66228..67010
                     /locus_tag="ACIZE9_000070"
     CDS             66228..67010
                     /locus_tag="ACIZE9_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGC6091972.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            67031..67738
                     /locus_tag="ACIZE9_000071"
     CDS             67031..67738
                     /locus_tag="ACIZE9_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HGC6091973.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            68000..70798
                     /gene="ileS"
                     /locus_tag="ACIZE9_000072"
     CDS             68000..70798
                     /gene="ileS"
                     /locus_tag="ACIZE9_000072"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGC6091974.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(70847..72373)
                     /gene="zwf"
                     /locus_tag="ACIZE9_000073"
     CDS             complement(70847..72373)
                     /gene="zwf"
                     /locus_tag="ACIZE9_000073"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGC6091975.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(72388..73035)
                     /locus_tag="ACIZE9_000074"
     CDS             complement(72388..73035)
                     /locus_tag="ACIZE9_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGC6091976.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(73219..73548)
                     /locus_tag="ACIZE9_000075"
     CDS             complement(73219..73548)
                     /locus_tag="ACIZE9_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HGC6091977.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            73725..74453
                     /gene="sfsA"
                     /locus_tag="ACIZE9_000076"
     CDS             73725..74453
                     /gene="sfsA"
                     /locus_tag="ACIZE9_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HGC6091978.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            74469..75482
                     /locus_tag="ACIZE9_000077"
     CDS             74469..75482
                     /locus_tag="ACIZE9_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6091979.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            75482..76759
                     /locus_tag="ACIZE9_000078"
     CDS             75482..76759
                     /locus_tag="ACIZE9_000078"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGC6091980.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            76822..79524
                     /locus_tag="ACIZE9_000079"
     CDS             76822..79524
                     /locus_tag="ACIZE9_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC6091981.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            79676..79993
                     /locus_tag="ACIZE9_000080"
     CDS             79676..79993
                     /locus_tag="ACIZE9_000080"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6091982.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            80023..80343
                     /locus_tag="ACIZE9_000081"
     CDS             80023..80343
                     /locus_tag="ACIZE9_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGC6091983.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            80451..81911
                     /locus_tag="ACIZE9_000082"
     CDS             80451..81911
                     /locus_tag="ACIZE9_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC6091984.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            81979..82200
                     /locus_tag="ACIZE9_000083"
     CDS             81979..82200
                     /locus_tag="ACIZE9_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6091985.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            82231..82413
                     /locus_tag="ACIZE9_000084"
     CDS             82231..82413
                     /locus_tag="ACIZE9_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HGC6091986.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            82413..82826
                     /locus_tag="ACIZE9_000085"
     CDS             82413..82826
                     /locus_tag="ACIZE9_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HGC6091987.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            82949..84130
                     /locus_tag="ACIZE9_000086"
     CDS             82949..84130
                     /locus_tag="ACIZE9_000086"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6091988.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(84201..84365)
                     /locus_tag="ACIZE9_000087"
     CDS             complement(84201..84365)
                     /locus_tag="ACIZE9_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6091989.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            84519..84592
                     /locus_tag="ACIZE9_000088"
     tRNA            84519..84592
                     /locus_tag="ACIZE9_000088"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:84553..84555,aa:Arg,seq:cct)
     gene            complement(84661..85800)
                     /locus_tag="ACIZE9_000089"
     CDS             complement(84661..85800)
                     /locus_tag="ACIZE9_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6091990.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            85972..86106
                     /locus_tag="ACIZE9_000090"
     CDS             85972..86106
                     /locus_tag="ACIZE9_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6091991.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(86099..86734)
                     /locus_tag="ACIZE9_000091"
     CDS             complement(86099..86734)
                     /locus_tag="ACIZE9_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6091992.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(86847..87482)
                     /locus_tag="ACIZE9_000092"
     CDS             complement(86847..87482)
                     /locus_tag="ACIZE9_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HGC6091993.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(87516..87977)
                     /locus_tag="ACIZE9_000093"
     CDS             complement(87516..87977)
                     /locus_tag="ACIZE9_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HGC6091994.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(88107..88538)
                     /locus_tag="ACIZE9_000094"
     CDS             complement(88107..88538)
                     /locus_tag="ACIZE9_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGC6091995.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(88556..88876)
                     /locus_tag="ACIZE9_000095"
     CDS             complement(88556..88876)
                     /locus_tag="ACIZE9_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6091996.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            89175..89951
                     /locus_tag="ACIZE9_000096"
     CDS             89175..89951
                     /locus_tag="ACIZE9_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HGC6091997.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            89966..90169
                     /locus_tag="ACIZE9_000097"
     CDS             89966..90169
                     /locus_tag="ACIZE9_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6091998.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            90185..90523
                     /locus_tag="ACIZE9_000098"
     CDS             90185..90523
                     /locus_tag="ACIZE9_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HGC6091999.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            90510..90689
                     /locus_tag="ACIZE9_000099"
     CDS             90510..90689
                     /locus_tag="ACIZE9_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092000.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(90732..91202)
                     /locus_tag="ACIZE9_000100"
     CDS             complement(90732..91202)
                     /locus_tag="ACIZE9_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092001.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            91289..91987
                     /locus_tag="ACIZE9_000101"
     CDS             91289..91987
                     /locus_tag="ACIZE9_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HGC6092002.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            92165..92506
                     /locus_tag="ACIZE9_000102"
     CDS             92165..92506
                     /locus_tag="ACIZE9_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092003.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            92499..93170
                     /locus_tag="ACIZE9_000103"
     CDS             92499..93170
                     /locus_tag="ACIZE9_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HGC6092004.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            93176..93868
                     /locus_tag="ACIZE9_000104"
     CDS             93176..93868
                     /locus_tag="ACIZE9_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HGC6092005.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            93865..94614
                     /locus_tag="ACIZE9_000105"
     CDS             93865..94614
                     /locus_tag="ACIZE9_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092006.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            94626..94895
                     /locus_tag="ACIZE9_000106"
     CDS             94626..94895
                     /locus_tag="ACIZE9_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092007.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            94901..95065
                     /locus_tag="ACIZE9_000107"
     CDS             94901..95065
                     /locus_tag="ACIZE9_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092008.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            95058..95357
                     /locus_tag="ACIZE9_000108"
     CDS             95058..95357
                     /locus_tag="ACIZE9_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092009.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            95357..95659
                     /locus_tag="ACIZE9_000109"
     CDS             95357..95659
                     /locus_tag="ACIZE9_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HGC6092010.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            95699..96064
                     /locus_tag="ACIZE9_000110"
     CDS             95699..96064
                     /locus_tag="ACIZE9_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092011.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            96554..96694
                     /locus_tag="ACIZE9_000111"
     CDS             96554..96694
                     /locus_tag="ACIZE9_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092012.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            96691..96873
                     /locus_tag="ACIZE9_000112"
     CDS             96691..96873
                     /locus_tag="ACIZE9_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092013.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            96886..97080
                     /locus_tag="ACIZE9_000113"
     CDS             96886..97080
                     /locus_tag="ACIZE9_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092014.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(97113..97325)
                     /locus_tag="ACIZE9_000114"
     CDS             complement(97113..97325)
                     /locus_tag="ACIZE9_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092015.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            97453..97653
                     /locus_tag="ACIZE9_000115"
     CDS             97453..97653
                     /locus_tag="ACIZE9_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092016.1"
                     /translation="MKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDKY
                     LGEGFCGDSLFDDERILKEETE"
     gene            97650..97922
                     /locus_tag="ACIZE9_000116"
     CDS             97650..97922
                     /locus_tag="ACIZE9_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH/PUA domain-containing protein"
                     /protein_id="HGC6092017.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            97923..98108
                     /locus_tag="ACIZE9_000117"
     CDS             97923..98108
                     /locus_tag="ACIZE9_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092018.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            98086..98442
                     /locus_tag="ACIZE9_000118"
     CDS             98086..98442
                     /locus_tag="ACIZE9_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092019.1"
                     /translation="MKKVNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVL
                     KIEQNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIR
                     GGVCEISLVKRLPRTR"
     gene            98402..98878
                     /locus_tag="ACIZE9_000119"
     CDS             98402..98878
                     /locus_tag="ACIZE9_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HGC6092020.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(99024..99752)
                     /locus_tag="ACIZE9_000120"
     CDS             complement(99024..99752)
                     /locus_tag="ACIZE9_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HGC6092021.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            99800..100078
                     /locus_tag="ACIZE9_000121"
     CDS             99800..100078
                     /locus_tag="ACIZE9_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092022.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            100080..100466
                     /locus_tag="ACIZE9_000122"
     CDS             100080..100466
                     /locus_tag="ACIZE9_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HGC6092023.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            100463..100843
                     /locus_tag="ACIZE9_000123"
     CDS             100463..100843
                     /locus_tag="ACIZE9_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HGC6092024.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            100955..101407
                     /locus_tag="ACIZE9_000124"
     CDS             100955..101407
                     /locus_tag="ACIZE9_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HGC6092025.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            101404..103131
                     /locus_tag="ACIZE9_000125"
     CDS             101404..103131
                     /locus_tag="ACIZE9_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HGC6092026.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            103195..104382
                     /locus_tag="ACIZE9_000126"
     CDS             103195..104382
                     /locus_tag="ACIZE9_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGC6092027.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            104354..104923
                     /locus_tag="ACIZE9_000127"
     CDS             104354..104923
                     /locus_tag="ACIZE9_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HGC6092028.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            104936..106300
                     /locus_tag="ACIZE9_000128"
     CDS             104936..106300
                     /locus_tag="ACIZE9_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGC6092029.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            106302..106580
                     /locus_tag="ACIZE9_000129"
     CDS             106302..106580
                     /locus_tag="ACIZE9_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HGC6092030.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            106561..106887
                     /locus_tag="ACIZE9_000130"
     CDS             106561..106887
                     /locus_tag="ACIZE9_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HGC6092031.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            106877..107215
                     /locus_tag="ACIZE9_000131"
     CDS             106877..107215
                     /locus_tag="ACIZE9_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092032.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            107205..107570
                     /locus_tag="ACIZE9_000132"
     CDS             107205..107570
                     /locus_tag="ACIZE9_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HGC6092033.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            107577..108203
                     /locus_tag="ACIZE9_000133"
     CDS             107577..108203
                     /locus_tag="ACIZE9_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGC6092034.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            108203..108667
                     /locus_tag="ACIZE9_000134"
     CDS             108203..108667
                     /locus_tag="ACIZE9_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092035.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            108862..111171
                     /locus_tag="ACIZE9_000135"
     CDS             108862..111171
                     /locus_tag="ACIZE9_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HGC6092036.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            111183..111887
                     /locus_tag="ACIZE9_000136"
     CDS             111183..111887
                     /locus_tag="ACIZE9_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGC6092037.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            111884..>113718
                     /locus_tag="ACIZE9_000137"
     CDS             111884..>113718
                     /locus_tag="ACIZE9_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HGC6092038.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
BASE COUNT        37716 a        19055 c        23760 g        33187 t
ORIGIN      
        1 ctctgagtca caaggaacaa tttcaaaaaa cagcttttca tgtttgatga atattgtgac
       61 ttgtgaccga ggagttggta ggagaacacc gtttaccaag aggttgtgaa aaagctgttc
      121 tgcatcaagt aataagaaga gccaagtaaa aacagtctct tatgttttta acttggctgg
      181 acttatcacc gtagatgtaa gcttttgaac gccgtttatt tgcaacaaaa ggggctgtga
      241 cacgattttt gtcacagccc tttttttgcg aacattcatt tagcaatttt tagaaacttc
      301 tgccgccacc gccaaaagtc ccgccaccgc tagaatgggt agtacttccg ccaccgccgc
      361 ttccaggagg tgggcttttg gggattcttc ttgtcgtgac aaaagaattt gtcagacgat
      421 cggttttttc agttaatttg atactggatt tttctcggaa tggatatttg tagatgcctg
      481 atttcaattg ataacgcgaa acagtcacaa aataaaagac aagactaagg ataagagcca
      541 aaacaacagc aatgatgatt tctactgtcg tcaaaacctt atagcgtgta attttgccag
      601 tttcttcgtc tacacgataa tgtcctcctg gaactccgtc ttccacatat gttgctgatt
      661 tagacaggta agcttttgca gcattgtaat aggcagcatt tgtcatctga tcataaacat
      721 catctaagat cgaatcgatt ctgctatcag tcaaataatc gatcatatta ccagaagtcg
      781 aaatgtagat ttcacgctgt cccatatcta atagcaatac tgagccattt tgatcatttc
      841 cgactgcgtc tcttaagtaa ttatcagcaa agtctcttgg ttcttctgaa ttagatgtag
      901 tcgttacgat caagactcgt cctttgattt tttcattcag cttttctgcc tgttgttcca
      961 aagattggat ttgatctgtt gtgaataacc cagcctcatc atttaccgta gctgtatctg
     1021 catgagtagc caccggccag ccaacactta ctagcaaaag aaagaataaa aaaaattttt
     1081 tcatcatatc aagtaacctc cgatcagaaa gaggatcgct agcccagcga aaatcccaag
     1141 agcggtcagt cccaattttt tctggctgat cggcaggaca ccgctgacct ttcctgtttg
     1201 tccattcatt gcgtagtagt agactttttt acttgagtca ttgcttcgat aagtaacaag
     1261 ccataccggc agtaatacgt aattatttac ttcgtttgtg attgaagcag aagttcgcac
     1321 accggtcaat gttgtatatc catttgcggt atcttttaac agcttctctg aatagtcttt
     1381 taattcagat tgaatctgtg atttgattgc ctcatattcg atatctcttt tttctgcttg
     1441 gaacccggct aaatactggc ttttaaaatc aattgcttta tctaacggga aaggttgcac
     1501 gccttcgacc atcttttgtt gcgtattttt tgataaggca ttttttacta gttctttaaa
     1561 agaaagcttg cctgctcttg aaacagcaaa ttgcttcgtt tctgtgtatt cgatgtcacc
     1621 tatccgccat atgcggataa ctgtaccatt cgcctgcatg gcaccatcta cttcagcatc
     1681 tgtagcccaa taagggaaat acacacctgt caacttatcg atttgatcct tattgaaaaa
     1741 agctttggga acaaaccatt ttttcttggt ccaagcgaga aatctgttga ttgcttcttc
     1801 tttctcgaca gcaaaaggaa gtactttatt tggcaagaat tctccgctta aacgtcccga
     1861 tagtacgacg ggattatggc agtagtaaca ataagtcgca gcagttgtcg catcagtcac
     1921 gatctctgca ccacagttgg gacaaagaaa aagatctatc gctgcggtat tatctgcaga
     1981 ttcgtccgct gtatctgaaa aaccgcctgc ctcgtcaacc gctttgcgct cggcttcatt
     2041 catatcggca agctgttctt gggctgtaaa agtaaaatct tcggtaggtg aaggttcttc
     2101 tttgctttct tcgccagcca tacgcgcttc tttttgcttt tgctcatatt ggctgacttc
     2161 ttcttctgta tagatattca ggcagtattc gcaatgaaat ttttggtctt tgggatcaaa
     2221 agtcaacgga ccgccgcaat taggacattt atgtgtaaga acatccatca gctgcacacc
     2281 tttctaaata aattaattaa cggggattcc tttaaacggt ttaccacagt ttggacagaa
     2341 tttagggatg ccgttggaaa gatccacgat ctcattgcat tcactgcatc gcatttgtag
     2401 cttaggctga acgttttcta caggtttggc agctccgcag ttggaacaga attttccgga
     2461 attttctgtc ccgcaaactg gacatgtcca agtatccgca tttccttgtg cagtttgttg
     2521 attttgtttt tctgcttgtt gtttgatttg ttcttggtta ttttgagctg cttgagaaag
     2581 ataagaacca tttgcattca ttcccatacc tacacccata aagccggtca ttgctcctgc
     2641 ttcatttttt ccggctgctt ccataccacg tgcaatggaa ccttgcacgt agccttcacg
     2701 tacgctagga tcacctagca tcgccccttc gttacgcata ttgatcagtt tcacagaatc
     2761 atcggtgtaa gaaatgctgg ctacagccac agaaacaatc tccatcccac gtaattcacg
     2821 ccaagaatca tccaatgcag tatccatgta tttgcttaat tccaaactct tagatggtac
     2881 ataagaaatc cgttgaccat ctgcagacat ctgattgatt gctgattgta gcgctgttag
     2941 gaattcagct aaatactgct cattgatatc attgatttcc acttgtgttt tgtttttagg
     3001 gattgcgttt gtataaaata aaatcgggtc aacgacatga atagaataag tgccatgtgc
     3061 ccgtaagaat aattctgcgt tatagaaatt gtcaaagtag ttcaacggcg cgcttgtacc
     3121 gaatttgatt ccctttattt cttggagatt gatataaaaa acttgttgtt tctgcggtgt
     3181 gacgccgcca aatttgaatc ggtcaaaagt ttcagcaatt gcttctttca gtgttccatt
     3241 gaacatggaa ggagctgcgt catttttaat ggtgtaataa ccttcctcag cggtataatc
     3301 gatgattttt ccaccatcga ccaaaagcat catcatgttt ggatagacat ggacgactgt
     3361 tccgtctgtt aaaacatctt ctgttccttt acgattggag ccacgtttgt catctttgcg
     3421 gactttgaca ccttttgtca tgaccgttgt atcactcata ttgtctggtt cgatgacttc
     3481 tagccattga tctgccagac cgccgccaac catacttgtt gctgctttga taagacccat
     3541 aaaaaattcc tcctctgatt cagctagtgc caaacaatta ttgtttattt attataccat
     3601 aggaagatgt gaaacttctc ggactagaga cggaattgaa atggaaaatt gcgtattgtt
     3661 taaatacctg aaaaagccga gaaggatagt agttttttta cctaatatca cgtataataa
     3721 gagatagtga attttttaaa aaagggggat ccttatggca tatcaagcac tttatcgagt
     3781 ctggcgttcg cagcgtttcg aagacatcgt tggacaaaaa gctgtgacac agacactaaa
     3841 aaatgctatt gtttcccaca aaacctcaca tgcctacttg tttacaggac ccagaggaac
     3901 cggaaagacg agtgcagcaa agattttcgc aaaagcaatc aactgtccga acagtaaaga
     3961 cggtgagcca tgcaacgaat gcgaaatgtg tcgatcaatt actgctggta cgcaagaaga
     4021 tgtgatcgaa atcgatgctg ccagcaataa cggagtcgaa gaaatccgat ttatccgtga
     4081 tcgggcaaat tatgcgccta caaaggcagc gtacaaagtg tacattattg atgaggtaca
     4141 tatgctttca acaggagctt tcaatgcctt gttgaaaaca ttggaagagc caaaagaaag
     4201 tgtcatattc atcttagcaa cgaccgaacc tcacaaaata ccagctacga tcatttcacg
     4261 gactcagcga tttgatttta aacggatcaa tacggcagat attgtcgaac atcttgaatt
     4321 tatcttgaaa gaatcgacta tcagctatga accagctgca ttgaatgtga ttgcccgttc
     4381 tgcagaaggc gggatgcggg atgcattgag tattcttgat caggcaatct cgtttagtga
     4441 aggaacaatt actttagatg atgccatgca agtgacaggt agcttaactg acgaaatgat
     4501 ggacagttac ttgagtgctt gcgtgaaaaa agaagtacca gaagcattgg aaacattgaa
     4561 ccaaattctc gcagccggca aagaatcacg tcgctttcta gaggatatgt tacaatactg
     4621 ccgtgacttg ctgatgtatc agcaagcacc taacctagtt gaggaacaat cgagtacgat
     4681 cagaagtaca tttacagaat tggcacaaac tgtttcagcg gatcagctgt tttcaatgat
     4741 aaagattttg agcgatactc aaaatgaaat tcgttttacc aatagtgccg ctatttattt
     4801 ggaagtcgct acagtcaaac ttgcacagct accgtctgct tctgttcctt cagcagatgt
     4861 agcatttgca gatgatcaga tagtaaaaca gctacaacaa gagattaagg aactaagaaa
     4921 cgaaatcaag gaactacgca gtaatacagg aattgagaat acaaaagtac agccggtaca
     4981 gcaaacaaat cataaaaaac agacaagtac ctatcgtgta ccgacggaac gagtatataa
     5041 agttctgcgg gaagcgacaa gacagcatct gaaccaagta aaagaagtat gggaagactt
     5101 gctgatgagt ctatctgtca ctcagcgagc aatgcttaaa gcaagcgaac cagttgcagc
     5161 tggacctaca ggactagtga ttgcgtttga ttatgagatt gtttgtcaaa gagcagcaaa
     5221 tgacgaagaa ttgcagcttt cggtacacaa caacttaagc cgaatgatca aagattatgc
     5281 gcctgatcct gtttatatta caagagaaag ctggccagaa cttcgaagaa attatttgac
     5341 gcaggcacaa gaagagggaa cagaaaactc ttttgcttct gaagactcag aaggagaaat
     5401 cgagttgctt cctcaagaac aagaagtacc agaagaaaca cttgtagtaa aagcagagga
     5461 actgtttggc tccgaagctg ttacagtggt agatgattaa taaaaaggag tagataatta
     5521 tgatgcgtgg aatgggcaat atgcaaggca tgatgaaaca agtacaaaaa atgcaaaaag
     5581 aaatggcaga agcacaagag ctgctaaata aaacagagtt tacaggtaaa gccaccaatg
     5641 aattggtcaa agcggttttt acaggcgatc gtcgcatgaa agatatccaa atcaatgaag
     5701 aagtcgttga tcctgatgat atcgagatgc ttcaggatct tgtcgtaatg gcagtcaatg
     5761 atgcgatcgc acaaattgat gtggaaactg agaaaaaatt agggaaatac gcaaaaggtt
     5821 tgccaggatt ttagttttaa actgaaggag taatgaatat gcaatatcca gaaccaattg
     5881 cgaaactgat cgacagctac atgaaacttc caggaatcgg tcagaaaaca gcgacaagac
     5941 tcgcctttta tacgatcgat atgaaagatg aagtagtaaa tgaatttgct aaatctttgt
     6001 taagtgtaaa acgcgatttg catttttgta gtatctgcgg aaacatcaca gaagaagatc
     6061 cctgcgaaat atgtagaaat ccttcacgtg atcgaagcgt tatcctagtg gtcgaagagc
     6121 cgaaagatgt aatggcaatg gaaaaaatgc gagaatatca cggactttat catgttctcc
     6181 atggtgtgtt atcaccgatg gaagggacag gtccagaaga catcaatatt tcttctctgt
     6241 tgcagcggct gcatgatgca gatgtaaaag aagtgattat cgcaacaaat gcaacaacag
     6301 agggagaagc aacagctatg tatctctcac gtctgatcaa acccgcaggt atcaaagtga
     6361 ctcgtctagc acatggtctg tctgtaggct ctgatatcga gtatgcagat gaagttactt
     6421 tattgaaagc tgtcgaagga agacgtgagt tataaatttc taattaagtg ttttttcaga
     6481 tacaatataa aagcagcaca agagatgggg gcaacaatgt gaacggacta tttattacaa
     6541 tcgaggggcc tgatggtgca ggaaaaacca gcatcttgaa tgaactttac cctcttttga
     6601 aagaagtagc aaaaacagaa atcattcaaa caagagaacc aggaggcatt ccgattgctg
     6661 aagagatccg agcagtgatc cttgatccaa aaaatgatcg gatggatgaa cgtacggaag
     6721 cactgcttta tgcagcagca agaagacaac atctagtcga aaaggttctg cctgctctgg
     6781 caaaagggaa aatcgtttta tgcgatagat ttgtcgacag ttctcttgct tatcaaggtg
     6841 caggccgacg catcggcgtt accgagattg ctcggttgaa tgagtttgct acagaaggta
     6901 ctacgccgga ttttaccctt tatcttgacg tagattcaga caccggatta agaagaatca
     6961 agaaaaacag acaaaatcaa atcgaccgtt tagattcgga aggtttggaa ttccaccagc
     7021 gtgtacgtca tgcttactta aagctggcag aagagaatcc ggaaagaatc cacaaagttg
     7081 atgcaagaaa aagctttgaa gaagtgctgc aaacaagtta tcatacaatt attgaacagt
     7141 atccgcaatt ttttgaaaac taggaaggtg aacgtttatg aaaattattt tagcgattat
     7201 ccaagacaaa gacagcaacc gtttatcaaa tgaattgatt gatgcaaata tccgtgccac
     7261 aaaactatca tcgacaggcg gcttccttaa ggctggaaac agtacgttta tcgtgggtat
     7321 tgaagatgac cgtgtagaag aagcattgga aatcatcaaa aaaacgtgtg aatcaagaaa
     7381 gcaatttgta tctacacctg ttacactgga tatttcgatg gatgggggcg tcccttatcc
     7441 agtagaagta gaagtaggcg gtgccacagt cttcgtctta cctgttgaag gattccatca
     7501 attttaggag gagctgagct atgaatcaag aaataaactt ggctcaaatg caaccgatcg
     7561 tgtatcagca gcttcaacgg agttttgagc atgggcgtat cgctcatgct tatctttttg
     7621 aaggggagaa aggaacagga aaacatgaag taggtatatg gcttgcacag cacctgttct
     7681 gtacccaaat gaaagacaat ctgccttgtg gaaaatgcaa caattgtcag cggatcgaaa
     7741 agaaagaaca tccagatgtt ttggttattg aaccggaagg acaaaccatc aaagtcgatc
     7801 agatcagacg tttgcagacg gaattcagtc gcagcggtta cgaatcaaga aaaaaagttt
     7861 ttttgatcaa agaagctgaa aaaatgaata gcagtgcggc aaacagtttg ttgaaattct
     7921 tggaagagcc ccctggagat tttttagcgg tgttagaaac agatgcagta ggaagaattc
     7981 tccctactat tcaatctcgt tgtcaagttc tgcattttca agaactttcg aaagaagcac
     8041 tgatccatcg attgcaagaa gagcagattc cattggaaaa agcaaaactt ttggctttct
     8101 taacaaacag tttaggaaaa gcagttgaaa tctctcaaga tgaatggttt aatgatgcta
     8161 aggacttgat ttatcaatgg ttcgtttact tgcaaaagca agatactcaa gcctttatct
     8221 atgtccaaaa aaaattggta aaatcattta aagaaaaaac acaacagttt acaggattat
     8281 ctgtcttgat gttttattat caggaagcac agcgtcaagc agtagcaaac ggcgaatatg
     8341 gcaaagtgaa acagataaac cagataattg aacggatatt gatcgcagag cagaaactac
     8401 gcagcaatgt cagttttcag gctgttgcgg aacagttcgt tttgcatacg attttttagc
     8461 ttgccgcaaa ggatgatgat caaggaggat ggaaatggta gaagtagtag gtgtccgata
     8521 tagagatgca ggtcatatct attattttgc accaggagac tctgaatatg tttatagtga
     8581 caaggtatta gtcgaatctc agcaatcctt acatattgct actgttgtcc ttcctaaaaa
     8641 agagattgat cccaatgacc ttcctgaagc tatccgtccg atcttgcata aagcgtcaca
     8701 agctgaatta gaaaaagaca aaaaaaacaa aaaagatgct tatgatgcat tgaaaatcgc
     8761 aaaagaaaaa gtgcagttgc gtgagttgga aatgaaaatg gtcaaagccg aatacacatt
     8821 tgatcgaaat aaattgattt tttctttcac agcggacggg cgaattgact ttagagaatt
     8881 ggtaaaagat ctggccgctg tatttcgtac tcgtattgag cttcgacaaa ttggtgtccg
     8941 cgatgaagca aagataatag gcggaattgg tccatgtggg cgtccattat gctgttcttc
     9001 ttttttaggc gatttcgtgc ctgtatcaat caaaatggca aaagatcaaa gtttatcttt
     9061 gaatccaaca aaaatttccg gtttatgcgg acgcttgatg tgctgtctgc aatatgagag
     9121 cgaagaatac gagacagcga aaaaagaact ccctgacttt ggaaaagtaa ttgctacacc
     9181 tgatggtaaa gggaaagtcg tagggttgaa tctgcttagc cgtatcgtta gtattcggct
     9241 gactggacgg gaaaatcctg tcgaatatga atgggatgaa ttgaaagaat ttatccaagt
     9301 aggtgagatg aatggataag agatcattat acgacggatt gaatcaatta gaatcagagt
     9361 tgagaaatac attaacagaa cttgttgaaa tgaagcatgc tttgcatgag atcgtagaaa
     9421 aaaatacaac tttggagatg gaaaatcaac gtctgcggga acacctgcgg gaattgaacc
     9481 aagttgcaca agctccagct gaaaatgtga agcaggaact ttctaagtct cgtatgaatc
     9541 ttgaaaaaat ttatgaagaa ggattccatg tctgctacga tttatatgga tcaagaaggg
     9601 acaatgacga gccttgtgcg ttttgtctag aagtgatcta tcgcgaaagc ggtcgatgac
     9661 caataacaag aggagactgg agcggagaaa tactgctcca gtctttttat taaggagatt
     9721 gtgacagatg tataatcaaa aaagtttcaa gggaaatccg gtatatgggg atttatatct
     9781 tgtaccgacg ccaattggaa atttagaaga tatgagctac agaagtgttc gtatgctgca
     9841 agaatccgat cttatcgcaa gtgaggatac gcgtaataca caaaagttat tgaatcattt
     9901 tgaaatccat acaccccaaa aaagtttaca tgaacataat tataaagaac gtgtccctca
     9961 attgattgct ttgttaaaag aaggaaaaac gattgctcaa gtcagtgacg caggaatgcc
    10021 ttccatcagc gatcctggac atgagctagt tttagcctgc ataaaagaag ggatttctgt
    10081 gatctctatc ccaggaccta cagctgggat gacggctttg attgcttcag ggctagtgcc
    10141 tcaaccattt ttattttatg gcttccttcc acgtaagaaa aaagaacaga aagaaacatt
    10201 gaaaaagcta aaagaacaga cagttacgct gattttttat gagtcacctt atcggatcac
    10261 tgctacattg acgaatttct tagaaatttt tggaaatcgc caagtcgttt tgtgtcggga
    10321 attgacaaag gtccatgaag aataccttag aggaagtacg gaagagctac tcgcttatat
    10381 cgaagaacat ccagtaaagg gtgaatgttg tctgcttgta gaagggaatt tgttcgaaat
    10441 gccagtgacg gaagttgatg aagagttggg aacgttaaag gaacaagtag aagcaaagat
    10501 cgcttcaggc gaaaaaccaa atgctgctat caaagcagta gcgctgaaaa atgggctgaa
    10561 aaaacaagaa gtctaccgtc agtaccatga attagactga gatagtataa gttgtctata
    10621 atgaaagact aatgaggaaa tcagctacta acttttcaaa tctcttgaac gcgaacgaat
    10681 gttcttgtat aatgaataag aggtgaggat gatggagctg caatttcctt tacataatga
    10741 tacatcaaga aaaatcattc atattgatat ggatgctttt ttcgcttcgg ttgaagaacg
    10801 agatcatcct gagtttcgcg gacatccatt agtaattgcc agacacccca gtgacactgg
    10861 tgggcgtgga gtagtgacta cagcaaatta tgaagcaaga aaattcggaa ttcattcagc
    10921 aatgagtgca caaaaagcgt atgagctttg tccgcaagcc atctttaagc ctggcgacca
    10981 tcataaatac agcgatattt ccaaacaagt acgggaagta ttctatcgtt atacagatat
    11041 tgtggaacca gttagtatcg atgaagcgta tcttgatgtg accgaaaata aaatcaattg
    11101 caagtcagcc atcaaaatcg cccgaatgat ccaagcagat atttgggaga gtgtccagct
    11161 aacatgttct gcgggagtaa gttacaataa gtttttggcc aaattagcat cagactatca
    11221 aaaacctaga ggaatcacgg tagttgcccc tcaagacgct gtgccatttt taaaagcttt
    11281 gccaattgaa aaatttcatg gggtagggaa gaaaactgta cctagaatgc atgagctagg
    11341 gatttataca ggaaaagacc tatatgaatg cacagaaatg atgttgattc gaaattttgg
    11401 aaaaatgggc tattctcttt atcgtaaagt cagaggaatc catgattctc cagtaaacgt
    11461 tacaagagag cgaaaatctg tgggaaaaga gcatacttat gggcagccgt tgcaaacgga
    11521 agaagcagtg ctgactcagt tgcgccaact agctgaaaaa gtagaagaag cactgagaag
    11581 agtccaaaaa catgggaaaa cagtagtttt gaaggtcagg tacacggact attctactgt
    11641 gaccaaaaga gtgacattgc cagaatatat ctataaaaaa gaagcactct tttatcaagc
    11701 aagccttata tgggaggaaa tcttgggagt agaaaaagga atccgattgt tagggattac
    11761 tttgacgaat ctggacccga tgacttatga aaacatcgtc cttccattat gggaaaatca
    11821 agaaatataa aaacagcttt gagagttgaa accggaaatc cgttttctct cccaaagctg
    11881 tttttatatc aagtcttgct ttttgatttg ttcataggtt tctgttgcat ccgtacattt
    11941 ttcccaaatc acaacttgat tggattctaa agatttttgg acgtcaatga tccgctggtt
    12001 gctacttccg cgaaattgta gttttaggtc acgtttgctt aattcaaagc gtccgtcaac
    12061 aaggatatcg atttgcgaaa ggagttctaa tttatcttct gaatcttgta gcaattcatc
    12121 aaaggtatag cctgtccatg accagatatc ttttgtcgta ccgaactctt ttcggatacg
    12181 tcgtacgact tgcagacaaa catctgtatt caaaaaaggt tcgccaccaa gtaaagttaa
    12241 tccttgcacg taatcgttgc gcaagtcagc gatgatttgt tcttctaatt caggtgtgaa
    12301 tggtttgcca tatcgaaaat tttgtgcagc tttgttgaag cagccttcgc aggcaaataa
    12361 gcagccacta acgtaaagac tgttgcggac accttcacca tcgacaaaat taaacggttt
    12421 gtagtcagca atatagtttt ggctgtagtc ttttgctaac cattcttttg gttttggatt
    12481 tctcataaaa aaacttcttt catttaaggt tcaaagatat agctattgaa gataaaatct
    12541 actcgaccac ataaataaga acaaactgac ctaaatccat tgttcaagaa agcttgttct
    12601 tattttgata gagggcgttc aaagatacaa agccatcgaa agagggtggt gaaaaaagac
    12661 ttgtcatagc ctcttattct gaataaacgg tgttcaaaag cttgcatctg cagtaataag
    12721 cccaactaaa cgaaaaatat gaggaactat ttttgtttag ctattcttat tacttgatgc
    12781 aggacagctt tttcacaacc tcatttcatg tgtttcacac gtgaggaaat ttctttatgg
    12841 cggccatgta ccatcggacg agcttgcgga tttcctaaat agccacaagt acgtttgact
    12901 acatcacatg tttttggatc atgatttcca cattctggac attcgaaccc tcgttctgtc
    12961 ggtttgaaat caccttcgaa accacattga tagcaatgat cgattggcgt attcgtacca
    13021 agatacccga ttttgtcata tgcaaaatcc catacagctt ctaaagcttt cggattttgt
    13081 tggagcatag ggtattcaca gtagtggatg aatccacctg aacaatattt tggataatcc
    13141 ttctcaaatt ccaatttttc aaatggcgtt gggtttttac gcacatcata gtggaaactg
    13201 tttgtataat attctttatc tgtgatattt tcgatgatgc cgaatttttc tgtatccaaa
    13261 cggcagaaac ggtcagttag actttcactt ggagttgaat agacactgaa atgataacca
    13321 tattcatccc cccatgcatc tgcattagct tttaattctt tgacgatatc aagtgtgaaa
    13381 gcttttgctt ctgggtttgt ttcccattcg ccaccgaaga aagctgaagc aacttcatac
    13441 aatccaatgt agcctaacga tacagtagct cgacggtttt tgaataattc attgacagaa
    13501 tcggtacgtg aaagacgttt cccgaaagca ccatacatat ataaaattgg cgcatttgct
    13561 ggaatggctt ctttacaacg ttctacacga tagagaagcg catctttcat gatttctaag
    13621 cggtcagaca gtaactgcca gaatttattc tgatctcctt ttgattcgat cgcgattctt
    13681 ggcaaattca atgtaacaac acctaaattc attcgtccga catttacttc ttgaccattt
    13741 tcgtctttcc acccttgcaa gaatgaacga cagcccatag gtactttgaa acttccagtt
    13801 aattcaacga ttttatcgta attcagaata tcaggataca ttcttttcgt tgcacattcc
    13861 aatgctagtt gtttgatgtc gtaattagga tcttcagggt ttaagttcac accttttttc
    13921 aaagtgaaga tcagtttagg gaagatagct gtccgctttt cactccctaa tccattgatt
    13981 cgaatctgta aaattgcttt ttgaatttct ctttcaaacc agttttctcc tagtccaaat
    14041 cctaatgaag tgaaaggagt ttgtccattt gaagtaaata aggtattgat ttcatattcc
    14101 aaactttgca tagcatcgaa gatatctttt ttggtttttg cttttgcata ttctttttgg
    14161 cgttctggcg aatcgatcca ttcttccgcg tcttttagat gttttttata gttcaattct
    14221 gcaaaaggag caagcaattc atctgttcgg tcggcagaac agccaccata ttgacttgac
    14281 gctacattgg caataatctg tgagatttgt gctgtggcgg tctggataga ttttggcgat
    14341 tcgacttcgg cattgccgat tttgaaccca ttgttcagca tgcctttgaa atcaatcaag
    14401 cagcaattcg tcatcggtgt ataaggatga taatccaaat catggtaatg gatatcgcct
    14461 ttttgatgcg catttgctat atgtggtggc aacattttca gtccgattga ttttccaacg
    14521 atcccggctg tcagatctcg ctgtgtattg aaaacattac tgtctttatt tgcgttttcg
    14581 ttcacgacag tttggtcctt gttgattagc ttttcaatcg aaaagttgat atctgttgct
    14641 ttactgcgag caaaatctcg tttggtacga taattgatgt actcttctgc taattcatat
    14701 tcgttttttt ctagtaatat atgttccacg atgttttgaa tctcatagat tttgacattt
    14761 tcagcaaacc ggcttttgat ttcttggaca accaagtctg caatcatttg aattttttca
    14821 taagtaagtg gtgataatga gccgtgaatt ttcttttctg ctttgatcag tgcttcattg
    14881 atcttttgtt catcgaaatc aacatggcgg ccatcgcgtt tgatgacttt catctgggat
    14941 gtctctggct gctgagtaac gacagttttt tcttcataat ttactttcat tatcttcaac
    15001 tcctgctaaa ttgttcttgt ctatcataaa acaaaatcgg ggaaggagca actaaatatc
    15061 ggctatatat agtattcaat gtgctgtata attggatttc tatactatat gtagtgtata
    15121 ttttattgtg aaaaaaggtg aaaacttgta gctggtggat ttgttttttg catatttaat
    15181 tttgctgaat aaaataattg aataaaattt tttattcagt ccaagtaaaa gtgacaaaaa
    15241 cataagagca aattattcgt agatatgcta ctatgcaaat aaatagaaat gaaaaatgaa
    15301 agaggaggag aagaattgga aaagatgatc gaagtgaaac atctaagtaa aagctacggc
    15361 agcaaacttt ctcccgtcaa agccttagat aatatctcat tcacagtaga agaaggcgag
    15421 tttgttggga ttatgggccc aagtggtgca ggaaagacaa cgctgatgaa tatcttgtcc
    15481 acgatcaatt tgcctacgat gggcagtgtc tcgatccaag gaaaagaaat cacaaaaatg
    15541 aaaaacagtg agctcagtga ctttcgtcga aaaaaactag gattcatttt tcaagagttc
    15601 aatttgatcg ataccctaaa tgcaaaagac aatatcctat tgcccctagc agttgaacgg
    15661 atgactaaag aggaaatgga aaagagagta agacatgtag ctcaattgtt gaatatagaa
    15721 gaactgctca aacggtatcc cgatgaactt tctgtcggac agagacaacg aattgcagct
    15781 gctagagcac ttgttgttca gccacaagtg atttttgcag atgaaccaac tggctctttg
    15841 gactcgaagt cggctacaga attgttgaac tacttgaaga ccatgaatca aaaagaaaaa
    15901 gcaacgatac tgttagtcac ccatgatcca tatacagcaa gctactgcga tagaatttta
    15961 tttattaaag atggtgtgat tttttctgaa gttgtcagaa gagggacaag aagagagttc
    16021 tttgagaaag taatagacat gcaggcgacg attggcggag gaggaaaaat gaatgctgta
    16081 taaactagcc gttaaaagtt tttttcggca gtcacgaggc tatcttgttt attttttcag
    16141 tttgacttta tccgtaatga tctattattc cttcagcgca atgacctacg atcaatcttt
    16201 agtcagaaga gcaagtcaag atacttcgat agatggtgga ttgagttttg gtggatttat
    16261 cattactgtt gttttgcttt ttttcgtatt cagtgccaac cgatttttct tgaatagaag
    16321 gcaaaaggaa ataggcatct atcagctttt tggtatgaat aaactgcaga tatcaggtat
    16381 atatgtgtta gaaatcatga taattggatt gttcgcctgt atttctggga tattactcgg
    16441 tattattttt tccaaactct tttcaatgat tttggttcga atgatggata tggatcttac
    16501 tagtccattt tttatctcca ttccatcagt agtagatact ttatttgctt ttttcatcat
    16561 ccttttagca gtatctgtat attcaatatg gaaaatatgg cgctatccaa tgattcgaag
    16621 ttttggagaa aaagaacaag cagatagttc aacaatgcgc ttcaggacaa ggcaccgatt
    16681 actcgcagtc atcgggttac tacttttaac gagcggatat tttggagcta gtcattttag
    16741 ggaaatcact tcatggatga tcagttatca ttatcttgat acattagttt tcttttttcc
    16801 ttttttaatt tttttcgttt gtgtggtcgg tacttatttg tttttctgtt atacatttcg
    16861 gttatttttg atcatattga gtaaatggaa gatttattac tatggtatca attttttgat
    16921 aatgggtaac acgcaagttc atttgctcaa aagttggcgt acaaattctc tgattacagt
    16981 cattctcgga atttctttaa tgacaattgg cggcacggct agtatctcta ctattttatc
    17041 ctaccaggag aaagtttcct ccccgatgga ctatcagttt gatgttgaga cagagaaaaa
    17101 aatcaagccg attctagcag aggaagggca gaagataact aaagaaatca ccttgcatta
    17161 taaagtcatt gggagtatct atagtcaaaa tctcgaagaa cctatgtttc aaactgctaa
    17221 tctgatcacg gaaacacaat atcaagcctt cagaaaagtt aatccagatt tgccgaacat
    17281 ttctttgaaa tcacctggtc atactgtttt gcttgatcaa atgcaaactc tttttcggaa
    17341 tatttcatta tatggatcta gtattggact gccagataat caagaattga agattcaaca
    17401 aatgcttcca agtgtattag gtgacgaaac aatggtatat ctaagtcctg tactgattgt
    17461 agatgatacc gtttttgaaa aagcaaaagg tgtggattat caagtagtca atgtagatgt
    17521 atcaggtgga aataatgaaa aaatagatga acgactgagc aatgacctgt cgataaagtg
    17581 gctcaatgct gtttattatt cttatgatat cgtaaatgga agtctacaag gagaaattag
    17641 cacaaagaaa cttccggatg accaaatgaa ggaagcacaa tttagccaag aaagctctcg
    17701 tttgaatttc tcttccagct attcgaaatt gcgtgcagtt aatcggcgaa tcggtatcaa
    17761 tatttttgtc acactatttg tcgggatgat cgtgattatt gctactggta gtattttgac
    17821 agtccggcaa ttagcagaag cagaggaaga aaaagaaaat tatcacctat tgactaagct
    17881 ggggattcca caaagaagga tcagacggat gatcttcgag caaaacgcac ttaccttctt
    17941 tccacccatg atattaggga tcactcacgc agtatttgca atcaatgtct tcactcagta
    18001 tataaaaact gccgattact ggttggctta tcttgtgagt ggcttattga tccttatcta
    18061 tcttttgctt tatgtcatta cgagtcagtt atattgtcgg attatcgagg aatgatatac
    18121 ggaataagac aagataataa atagaactaa attttgaata ccatttattt ggaataagag
    18181 gttgtgacac gatttttgtc acaacctctt tattttttat attttttaaa agtacgagaa
    18241 attataaaga aaaaagcagt gatttgatgt gctattttta taaaagctat gtgacaaaac
    18301 tgttagtaaa aaaacggttt ctgtaagcta gacacatgtt tctttttgtc aaaattagtt
    18361 acactttgtg tgaggttata tgaggaggga atccaatgaa caaatggcgt tctaatccaa
    18421 aattgaatta ttggggaaaa ttcatcattc gaacaatttt ttatagtgca gtactgctgt
    18481 tcctgattta tctgtatcac tataaaaata ttcaaggagg aacttttatc tataacgaat
    18541 tttaggagga agagtatgga aatcaaaacg attattgaag caatcgatga ttggggaata
    18601 aatgaacctg atcgagttgc ttatcaggcg gatgagacgc atacttttgg tgaattgaaa
    18661 caagcatcag acgcacttgc ttattattta gaaaaaaagg tagaaggcga tggaccaatt
    18721 gtcgtttttg gcaatttgga gtttgaaatg attgtctcat ttctaggggt tgtcaaatct
    18781 ggccatgcct atttgccgat tgaagagcat acacccaagg agcgtatcct atcgatcttt
    18841 cgggtggcta aaccatctat ggtcatcagt atcggggact ggatagaaga tattccttcg
    18901 gttcctgtca taacaaaaaa agaatttcaa gaaatcaaga agataccagt aggattttat
    18961 cccagaaata gcgtaaaagg tacagaaaat ttttatatta tttttacttc tggtactact
    19021 ggagaaccaa aaggcgtaca aatcagtcat gataatctag tcagctttgt tcaatggacg
    19081 atggaagact ttgggatcaa gcctggtatg catttcttag cccaagcgcc attttctttt
    19141 gatttatcgg tattttctat ttatcctgca ttagtttctg gcggaatgct gaagccgtta
    19201 aataaagcag ttgttcaaga ctttcgtcaa ttattcgcga cattgccagc cttgaagttg
    19261 aatgtgtggg tttctactcc atcatttatg gatatttgct tgatggaacc tacattcaat
    19321 ggagaaaatg tgccggaatt ggacatgttt ttattttgcg gagaagaatt gacgaaaaaa
    19381 actgcagaaa gtctacttga tcgattccca aatgcacgga tatataatac ttacggtcca
    19441 acagaagcaa ctgtagctat ttcaagtatt cagattgacc agcatgtact agatagttat
    19501 gaccgactac cgattggcta cgtaaaaaaa gacacgaaag tttctattgt ccaagaaggt
    19561 aaacctgttt caaaaggaga aacgggtgaa atcattattg caggaccaag cgtatcaaaa
    19621 ggttacctga acaatcccga aaagacagct gctgcgttct tttgtcaaaa tgacttagca
    19681 agttaccata caggggatgc aggtagacta gatgaatatg ggcttttatt ttatgaagga
    19741 cgtatggatc agcaggtcaa attacatgga taccggattg aactcgggga tatcgaacat
    19801 tatctgctcc aagacaaccg aatcaaacaa gctgtcgtcg taccaaaata ccaaggaaca
    19861 aaagtacagc agctggttgc ttttgtcgta ttagaaaaca aaacgaaaca gccggatttt
    19921 cagttgacta aatctatcaa agaacaatta ctagaagttg taatggatta tatgattcct
    19981 cagaagttcc attatgtcga tctgctgcct cagacagtta atggaaaaat cgatcgaaaa
    20041 aaattaacag ctgaggtgaa tcctgaatga tgttacctca tatgatccct tatgcagagc
    20101 cgttttattt ttttctttta gccattgcgc ttgtaccgat cgttctatct ttattgatat
    20161 gggaaaaaag attaccagtt tatcaatcag cagtgacact tttcttttta tttgtcagct
    20221 ttggaggtaa ttattggcaa cagggagcgg cgctgattgg gtatgttttg tggcagacga
    20281 tacttgtatg gggctatttt gtttatcggc aaaggaaaaa tcagacagga tggttttttg
    20341 ccgccgttat tttagcgata attccactgt ttttaacgaa agtgactcct ttttttgaac
    20401 atggaaaagc atcgttactt ggttttttag gaatctctta tttaaccttt aaatctgtac
    20461 aaatgatcat ggaaataaga gatggcatga tcaaaacata taagccattt cgttatatcc
    20521 agtttctgct gttctttcca acaatctctt ctggaccaat cgatcgctat aggagatttg
    20581 aaaaagatca gctccatccg cctgttcgtg ataaatatgt tgatcttttg ggaaaaggcg
    20641 tccaaaatat ttttgtcggt tttttatata aattcattat cggttattat tttggtcaag
    20701 tactgcttcc tgtagtggga cgcattgcct tacagcatgg tggtatttca tgggcattag
    20761 taggttatat gtacgtgtac agtatgtatt tgttttttga ttttgctggc tatagcttat
    20821 ttgcagtcgg tacaagctac atgatgggat atcagacacc aatcaatttc aataaacctt
    20881 ttttatcatg gaatatcaaa gaattctgga atcgttggca tatgacgctg tccttttggt
    20941 tccgtgatta tgtatatatg cgattgatgt tcttcatgat gaagaaaaaa ttttttaaaa
    21001 gcaagatcgt aatgtcaaat atcggttatt ttgctttgtt tcttctaatg ggtatatggc
    21061 atggattgac gtggtactac atcgtatatg gactgtatca tgcttgtctg atctgtctga
    21121 cagatgcatg gatccgattt aagaagaagc ataaagagca gttgccttct aacaaattta
    21181 cgcatggctt agccgtattt ttgacatttc aagcagtatg ttttagcttc ctgatttttt
    21241 caggattttt agataaactt ttttttagct aacgaatagt gacatattaa tttatataac
    21301 aaaggagaaa aggaaaatgg aagaacaaat tttatcaatc ttagaagaaa taacaggaac
    21361 agatgaagta agaaaaaatc gtgatattga tctatttgat gaagggttgc ttgattcttt
    21421 agcatctgtt caattattag tcgagctaga cggagagctg gatatccaag tccctgtatc
    21481 tgaattcgag cgagaggatt ggtgcacacc gaataaaatc attcaacaag caactgcatt
    21541 gaagggttga gtatgaaaaa gaaacttttt gctattttcg gcccggttgt tttagctgtt
    21601 ggcttactgt ttgtgttttt tacctcctcc tatcaagtag atatctctaa tccagaaacg
    21661 attagacgtg cctcttcttc catgtcagtg aacgtgttga aaggagatgc gataaaaaat
    21721 tatgcattat ctgaaaaaca atatattcct ttttttggct caagtgaatt aagcagaatc
    21781 agtccatttc atccgtctgt tctggcagaa aaataccagc gaaactatcg tccatttttg
    21841 ctgggagcac ccgggacaca atcgttaagc caatatatga tgatgcgttc tgcaggagat
    21901 gctatgaaaa acaagaaagt cgtctttatt atttctcctc agtggttcgt taaaaatggt
    21961 gtaaaaactg attactttaa tacgtattat tctgaacttc aaacatacga ctggttgttt
    22021 tcaatgaaga aagtaacgcc tgctgatcgc tatttagcta gaagattatt aactttctca
    22081 aaagtaaaag agaatgatac gttgacggcg attctgcaaa cgatcaaaaa agggaagcta
    22141 cctttacctg aatctttgaa tcagctgcgc agccaatgga acatgctgaa gagagaggat
    22201 gaagtattca gcaatattgg gttgaaagat cgacagcaaa aaatcgatca tgagtcaaaa
    22261 cgattaccaa aacaatacca agaaacagaa ttatccattt tagcaaatca aattggagaa
    22321 cgagaaacga cgaataatcc attcgggttg aaaaacgatt tttatacgca tcgtatccga
    22381 gcccacgagc cagagctcaa acagtcacaa aaaaattggg attatcgttt ttcgccagaa
    22441 ttttctgatt ttcagctggt cttggatcaa ttagcaaaaa accataacga agtattgttc
    22501 atcatcccac cggttaacga gaaatggagc gattataccg gactatctca agaaatgtta
    22561 caaggatttg ccaaaaagat caaatttcaa ttaaatagcc aaggattcaa tcgaatagct
    22621 gattttgtca atcaagcggg taccaactat tttatggaag acacgatcca tctaggctgg
    22681 aaaggctggt tggctgcaga tcaacagatc agaccgtttt tagaagaaaa tcatattact
    22741 gctagtaagt atcatcttga cgatgctttt tttagcaaat cttggcaaca tcaaatacca
    22801 gataaactac aattaaaata aagaaaacag gcgagtgttg ctcgcttgtt ttctttattt
    22861 ttgaatattc tgaataaaag ataaaaatac caagtttgcc tgaacaaaaa tcataagcaa
    22921 tggtataatc acaatatgaa tatagaaatg ggggaaaaca tttggataca aaagaagaac
    22981 agctacttat tgatttaact tctgcaaaag gagtacctgg aaatgaagaa gaggtaagag
    23041 aagtattcag agaatatgcc aaaccattcg ctgatgatat tttttatgac ggtttaggca
    23101 gtgtgattgc caaacatggt gctggcggag gccccaaggt ctttatttct ggacatatgg
    23161 acgaagttgg ttttatggta acaaaaataa ccgaaaaagg attcttggaa ttccaaactc
    23221 ttggaggttg gtgggggcaa gtcatgcttg ctcagcaagt tgaaatcaaa acacgtgaag
    23281 ggaaaatcgt ccacggtgtg attggttcca aaccaccaca tgttttaaca cctcaagtaa
    23341 gaaataaacc ttatgaaata aaggatatgt tcattgatat tggcgcatca agccaagaag
    23401 aagccaaaga gtggggcata cgtcctggag atatggtcac tccatatatt gaatacaaac
    23461 gaatgaatgg cagtaaatat ttactggcaa aagcatggga taatcgtatc gggacagctg
    23521 tttctctgcg agtattagag aatctatcta aagaagcaca cccaaatgtt ttattcgcag
    23581 gaagcgatgt gcaagaagaa gtaggcttgc gaggtgctcg aacaagtaca caccttgtaa
    23641 atcccgatat tgcttttgct ttagatactg gtacagcagg agacactcca ggaatgacac
    23701 caaaagaagc agattcgatt ttaggaaaag gcccacagat tttgattttt gatgcatcta
    23761 tgatcccgca taaaaaatta ttgaattttg ttattgatgt agcagaggaa atggatattc
    23821 cattccaata tacagtgatt tctggcggag gaactgatgc aggacaaatg catttgacaa
    23881 gagatggtgt tccgtctgta gccattaccg ttcctgttcg ttatctgcat tcccatacat
    23941 cagtgattca tgaagatgat tatttgaata cagtgaaact agtcacagaa ttagtgaaac
    24001 ggcttgatag tgaaacagtt gaaaaaattc ggagttatga ataatgaata atagaatacc
    24061 tatttctgaa tatcggaaaa aagcacgagt ttctttggaa aatcaatggg gaatcaatac
    24121 ttggcttgtt ttcttatcta taatatttac gagcgtcatc cagaactttt ttgacggttt
    24181 cagtcctttt ccggaagaaa gcatgcagca gcacttattg agttttctag tcgataattt
    24241 acttttattc gcattcaact atgcattgtt ttacattgcg ctagtagttg tacggggtgg
    24301 cagaccaaaa agtaaccttt tattttcagt tttccaaaga aagtattttg gttcgatact
    24361 tggcatcaat ttgatcaatt cagtcatcaa ctggctactc aacagtttaa tctttctgcc
    24421 catgttttta atcagcggag tgagtactta tatgcagctg cttttcagtt caaatgcggt
    24481 acctacgggt gtcatgccag aagattttct tgatatcagc tttgttttat cgatgatagg
    24541 gatgattttt gtttcagcac tcatcatgag tattgttggc ggtttattcc aatttgctgc
    24601 atggacaaag ttcgactatc ctgatttgtc ggttattcaa tgtttgaaat atggctggtt
    24661 tttattgaaa gatagaattg gtacgtatat tttgttgcag ctgtctttta tcggctggta
    24721 tttgctagga gcaatcgctt tgttcatcgg tcttttgtgg gtcattgttt atgtgaatgt
    24781 gtcagttgca gaattttatg aacaagcacg gattgaaaaa ggaggtccag acgcctattt
    24841 tacttagcat gtaagcagtt tattcatcaa aaaaataact tttgtggtag gataaatctt
    24901 tgagggggaa tgtacgatga aattaactgt tttaggatgc ttaggagcgt atccttataa
    24961 aaatcaaggg acaacaggtt atttgcttca atctgacggg ttcaatttgt tgatcgatgc
    25021 aggtagtgct acgctgatca aattacaaga acaccttgat ccacttgatc tagatgctgt
    25081 gatccttagc cattatcatc atgatcatat tgctgacctt ggtgtattac agtattactg
    25141 gcaacttcat cctaagagaa atccggagac attgctttca atttatggac acacaaaaga
    25201 ttccattcac tttgaagaat tgacgttgga aaatgtctca aaaggacatc cttattttga
    25261 agctgaagaa ttaaaaattg gtccttttct gattactttt atggaaacaa tccatccagt
    25321 agtatgttac gccatgcgta tcgtagaaga aacaacgggg aaagtattcg tatttacagg
    25381 tgattcaggt tatttggaaa gtttcgctga ttttgcgaaa gatgctgatt tgtttctagc
    25441 agatacctat ctttttgaag gaaatgaaca tcatcatgcc catttcactt caaaagaagc
    25501 tggagaactt gcgaaatcag ctaacgtaaa gaaacttgta cttacacacc tacctcagtt
    25561 tggtgattta gaacaattga aaaatgaagc gcaaaaggca gcaggcaaag ggattgatat
    25621 agaacttgct gcagttgaca aagtgtttaa catttaggag gaagaacatg atttttgtac
    25681 caaatgaaaa ccacgaccca agaatcaatt tagcaattga acaatatttg ctgcaagaaa
    25741 tgcctttaga tgaacctatt ttgctctttt atatcaatga accttcaatc atcatcggca
    25801 gaaaccaaaa tacgcttgaa gaaatcaatc gagattatgt ggaagaaaat ggcattcatg
    25861 ttgtccgtcg cttaagtgga ggcggagctg tctaccatga ttttggaaac ctgaacttta
    25921 gttttatcat gcctgatgat ggggattcat tccgtgactt tgcgaaagta acacagccaa
    25981 tcatccaagc acttcatgaa ttgggtgttg ctggggcgga attgaaaggc cgaaatgatc
    26041 tagtcattga tggcatgaaa ttttctggca acgcgatgta tgctaccaac ggtcggatgt
    26101 ttgctcatgg aacaattatg ttcgactctg atatcaatga agtagtcaat gcattaaaag
    26161 taaaaaaaga caaaatcgaa tcaaaaggaa tcaaatcgat ccgttctcgt gtaacgaata
    26221 tcaaaccatt tcttccagaa gaaaagcaaa aaatgacaac agaagaattt cgtcaagaaa
    26281 tcttgttgaa aattttcggc gtagagtcag tagaagaagt aaaaacgtac gaattgactg
    26341 atgaagattg gaaaaaaatc aatcgaatct ctgaggaata ttatcgaaat tgggattgga
    26401 attacgggaa gtctccagat ttcaatttct ctcgccaaaa acgtttttct atcggttcga
    26461 ttgaagtcca tttgaatgtc tcagaaggaa tgatcaaaga agcaaaaatc tttggcgatt
    26521 tcttcggact aggagatatc tctgacgtgg aaaaaaaatt ggttggacag aaatatgata
    26581 aagcatctct atcaaaaata gtcagccaaa ttgatgtgaa gaaatatttt ggtgcgatag
    26641 aaccagaaga attgcttacc ttactttatt gaaaataaaa aatagcggaa tccacatata
    26701 tggattccgc tattttttat acaggattcg ggtaatttcg agagagttga acagtgatcc
    26761 gatcaatgaa agtatctttt tcctgcgtta gtgttcctgt gtaacgatcc gctacgtctt
    26821 tcatcatcat taagtcaaaa cgttcctgat catctaattc ttctgtgatg cctcgactaa
    26881 ataggtttgt atcgtaatgt gcactatgtt cgcaacaaat gacgaaatgt tcctcttgtt
    26941 cgtgtatcga caaataaatt tttcgataca gtggattttc gatggcatga gtttctctaa
    27001 aggaatgctc taaagcgtgg atcaaaagtt gagccagatc gtcatcgttg ataggaagtt
    27061 cttcgggaag atctgcttgg aaggttatct gaatattccg tttggcagct aacttctggt
    27121 aacgcgctaa gataagattt gtcacctggt ggttgcaaaa agaacacagc atttcgaaat
    27181 tttttgcttc ttctaatatc ttttccacat agtttttagc ttttgtttgg tccgtatgca
    27241 ttaaatcttg cagattctcc atctcttgga caaattccag gcgaagtgta tttacttctt
    27301 ggatatgctg tcgaagctgc tcataatgtt gctccaacaa atcatttttg atttttaaga
    27361 aatctacttg tctccgatct ttgtcggtat ttaagatgtg atcgattaga ttgtagctga
    27421 taataacgat tagaatgata atatataaaa tcgtagacca attgatcgtt gtttgataga
    27481 tacctaatgc cgtttggatg taaatcaagc aatggataat ggctaccaag acgatccaag
    27541 gtgtacaagc tacataaaaa cggttattct tatatgcttc gccaatgcat gcaagtgaag
    27601 tgactaaagt gcttataaca ctagcaatat tagcaatcgg cattaattca ggaagttctg
    27661 caggagtaaa agttgcataa agcagaacgc cgataaaaat caaaagttgg aacgtacaaa
    27721 aaattccgta ccatttttta tagtaaaaca ttcggctcca atagtagcag atgatgaaag
    27781 ctgacgttaa gataataaat aaatgagata aaaaagaatg aacgaatggt tcaaaaagaa
    27841 taccacttaa aatatcttct gatacagctt caaatcctaa tgccaaagca aagcaactta
    27901 agagaataag tgagtattca agacgttttt gtttatacat caagtagatc gtatagaaaa
    27961 aggtccctat agcgataaaa acagcgatta tcatcgtcaa tacttgcggc actgattgtg
    28021 aataaataaa actaatcaat ggtccagttg ttcctagata aactttcggt ggcagtccag
    28081 catagttctg ataaggagat gagactgtaa gggtcaattt ttttccgata taatttgctg
    28141 gtaaatctat cacagccaat gagagtccgg gattgctttc ttcctgataa tctttccgtt
    28201 ggtataaaat cttttcgcct agatatacag taatccattg atggtttcct ttgattagta
    28261 aatttgcttc gtccaacggt ttttcaagtg tcgtttccat aatgaatgtt tcgtctttat
    28321 ccacggtagg aatcgtacga gtgtacttgc tgtcaaactt aaaatcagga tcatcttttg
    28381 tatagaaaac ccacgaatct tttatttctt tcatttgatt gctgtccgca ggagaaaaaa
    28441 taaaataaaa gaaataagca attcctgtta aaaataacaa tgataatata atgattatgc
    28501 tccactttat acgtaaataa aaagattctt ttttattata tatgttatta aaaaaagaca
    28561 taaaggtatt cctttctaaa acttgtaatg ttagggtaaa cgttttttaa actaacgtca
    28621 attatttata ataaaaaatg agataaagat gaggaaatag aattagaaac atataattat
    28681 taaagggaaa catttttaca gctataattt gaaaaaattt atcgttatta tatgattaag
    28741 aaggattgaa taaagaaaga agttgaaaac gatacctgat tacaaaaaaa taacttttat
    28801 aagttctata acgttgatta tatttttaat tcttattctt ctcgtcgtct tggttccccg
    28861 aatttttggt ttgactcctt atattattga ggacaaagaa atgagtccat attatgcaca
    28921 aggaaatctg atatatgtac gaccgaaaaa tacaaatgag attttagtcg gagatattat
    28981 tacatattat gaaaattcag gaaaaaaaat ctcgacgcgt cgcgtaatag ccgttgaaaa
    29041 caaccacgaa gatttttata caaaagctga tacaaagact tatattgagc ctggagtagt
    29101 aaaaaagaga aatattatcg gtagtcccat ctttcagatt ccatatattg gactagtcct
    29161 ttcaaaaacg gcatttgcat ggattcaggg gttattcttt acgattgctt tttgcctaac
    29221 aggaatcaca gcatggaata cctttgtaga gttgaaaaag aagcggagac gaacacagaa
    29281 atttttgtaa gaatgttaaa aacataaatg tattccagag atccaacgac tcttctgaac
    29341 atgaaacacg agaaaacact catgcagctt gtagatttag tcagttgttc gtataatgtg
    29401 tgaagaggag gagtagtatg cgcaatgaaa tgatgcatcg tcctgtagtc aaagaagaac
    29461 tattggattt tatgcgtacc cagcaaaaaa aattaccggg tgagctaggc aaactggaag
    29521 aagaagctca tgtagcagaa gtaccagtta ttccccatga aacagttgta tttttgaaat
    29581 ttttacttgg acagcttcag cctgaacgaa tcttggagat cggagcagct atcggttttt
    29641 catcaagtgt catggccacg acaatcggag aaaacgctca tgttacgaca attgatcgtt
    29701 tcgatgtcat gatcgagaaa gctaaaaaaa actatgaacg tctaggactg acagataaag
    29761 tgactttgct tgaaggtcaa gcagcagata tcttgccgga gttgtctggt ccgtatgact
    29821 ttatttttat ggatagtgca aaatcaaaat atattgaatt tttacctgaa tgcttacgtt
    29881 tgttaagaaa aggtggcgtt ttgatggtag atgacatctt ccaaggagga acgatcttgc
    29941 tcccagatga agagattccc cgtggcaaac gagctatcca tcgtaaatta aatgaatttc
    30001 ttcgtgttgt gatggatcat cccgatttga catcgacaat cttgccatta ggtgatggtg
    30061 tgatcttaat gacaaaggaa tcagaaacaa tcgagttgtg atacatgatt atggcagcct
    30121 gtagataatc gattgaatcg agggctcaat tcgaacttga tgtaaaagtt tctatatttg
    30181 taagtcaatt aaaggataca ggaaatctaa ataaacagga gtagcatgaa gtcaatgtag
    30241 ctcctgtttt caattgataa ccttagaaca gctgaaggag aatgtctcgt tttaaaagat
    30301 tgatttagta gttgggccaa aataattcat tatttgctaa ttaaataact atttcgtatt
    30361 gacagaagca atttaattat ctataattat tgatgttccg ctgattcttg tcatagtagc
    30421 tcagctggat agagcatccg ccttctaagc ggacggtcgg gggttcgaat ccctcctgtg
    30481 acgctaaaaa accgttagaa actgaggttt ctaacggttt ttctttgttt tttgtgccaa
    30541 tattgtttgt tttcaaaggc aaataaaata aaaaaacatc cttatcgagt acaattataa
    30601 ggagcaaaaa aataaaactc atcagaaaag aggaagaaga tatgacgata ctatctagaa
    30661 ttttagtgac tctagttgca attgaatttt tttatatcat gtatatcgaa acggtgagaa
    30721 ctgattctga cacgacaagt agggttttta aaatgagtaa agaagagtta agcagaaaat
    30781 ctgttcaaac attgtttaag aaccaaggag tgtacaatgg actattagga gtgggactac
    30841 tttatggagc ttatctttct tccgcatcta aagaaatcac aagtatgcta ttaatatcta
    30901 ttttttttgt tgcattatat ggcagtttga ctagcgatcg ttggatttta ctcaaacaag
    30961 gtgggctagc tctgttggca ttgctttcta ttttcttata aatatagaaa aaataagaat
    31021 ttatctaaca ggaaactttg tgaaaaatat tactttatct catgaaatat gatattctaa
    31081 tgaatggtat tttagaaaat ttcatgaaaa aggagttaga taggtgttca aaaattatgt
    31141 ttcctcacta aaaaaagaat tttcaggtta tgatctttca agatttcaga aagatctttt
    31201 ggctgggatc acagtagctg ctgtagcatt gcctttagcc ttggcttttg gggtatcaag
    31261 cggagctgat gcggccgcag gtttgattac ggctatcatt gccggtatcg ttattggcgg
    31321 tttatcaggc ggtttttatc aaatatcagg tccgacaggt gcgatggcag ctatcttgat
    31381 gtctattgcg gcaacaaagg gaatgcaagg tgtattgctt gctacttttt tagcgggtct
    31441 atttttactt gcagcaggac ttttccgatt aggaacactg acttctttta tcccagcacc
    31501 cgtaattacg gggtttactt caggtattgc tatcattatt gcattaggtc agatcgataa
    31561 tttatttggt gttcactcgg aaggtacaaa cgttattgaa aaactaagta gttatcaaac
    31621 gataggattt ccgataaaca cagcctcttt gatcatggga gggctagtca ttttagggat
    31681 gtttatctat ccaaaaaaat gggcgaaacg aatgcctagt tcgctgctgg ctatcatttt
    31741 ggcaacagca gttatgctat tgttccattt accagtagca actgtgggta agattccaca
    31801 aacattgatc agtagtaatc gtttgaatat gggagatttt agcttttctg ccttgcaaca
    31861 agtggcagtt ccagctatta gcattgcttt attaggaatg attgaaagct tgctatgtgg
    31921 tgcttcggct ggccgaatgg caaataagcc cttagatagc aatcaagaat taatggcgca
    31981 aggaattgga aatctgttgc ttcctttctt tggcgggatt cctgctactg cggccatcgc
    32041 ccgtacaagc gtggccatca aatctggtgc acaaactaga ttagctggta tgatacatgc
    32101 agttgtctta ctgctctcca tgcttgtttt tgcgccagtg atgtcacagt ttccaatgcc
    32161 agcacttgca ggtgttttga ttgtgacggc ttggcgtatg aatgaatggg aaacgatcaa
    32221 ggagctattt actaataaat attggtcagc agttctattg tttatcctta cgatgatttg
    32281 tacagttatc tttgatttaa gtattgctat cgtgatcggg gtgatcggcg gctgtgtatt
    32341 ttttgttgtc aaaagcgctg ctatcacgat ttcattagaa acgatcgatt ggcaaagaat
    32401 ggggctgcca gaaacggaaa agctgaataa ctggacagta gtgtatatta gtggtccact
    32461 gttttttatg tcttcagaaa aactcaaaaa taaattggaa gaactaaatc atcacgatgg
    32521 tgtcattttc tccatgcgag gcgtaccaag tattgatttg acggcacgtg cagtttttga
    32581 tgaatttcaa gaaaaagcag agcaaagagg acaaacgatt atctatactt ccttgcagcc
    32641 agaagtagaa aaacaacttt ctcacttgtg ggaacataca ttcacgcatc aacatcaaac
    32701 agttgctcat gcgttgacag ctttacatgc gaaatatact gcaattagcc attaaaacaa
    32761 tgaaaaagaa cagacaagac tgtaaactga agattttatg gtcttgtctg ttctttttaa
    32821 tattgctgta aaagtgaagc tagtacttgc cagtcttgat ggataacagg tacaagggag
    32881 cgattgtaga aaatagctgc tggatgaaaa agtggaagaa ttcgatagtt tttttctgac
    32941 cattcgtagg catccttttg ttctgttaat tgtaagacag gccctgtata gagttgacca
    33001 tgatttttgg taaccgtata ttctttgcca agtaaacgtt gaagaccaat gtttccaagt
    33061 gtcgcaatta attttggctg gaccttcatc agttcgtaat ccaatattgg tgcatgcgca
    33121 aatacttcgg aacgagtagg tgtccgattt ggataaacag tttctgactg ttgtgtccgt
    33181 ttattgatcc gatgagtcac gcgatacggg cggctcctta cagcactggt gatatacacc
    33241 tcttctcgtg ttaagccagt tgaagaaagt gcctgcatca attcttttcc agcttgaccg
    33301 ctaaaaggaa catgcgtatc aatctctgtt ttccctgggg cttctcccac gagcatcagt
    33361 ttaggatgaa gaggtccttg cccagcgata aatccttcta caggacggcc gttcattctt
    33421 aaagaagctt cttgtatcag ttcttttggg tattccattt atgctcctcc tttttctttt
    33481 attataagaa taaaagaaac acaatgcgac tattttattt ggtagaactg tgaggataga
    33541 aaagcagaag tattgcttga atttttgttt tactttttga ttttaaattt agttgactaa
    33601 cggttgctgt tctggtaagc tagtactgtt gtaattgtgg actccacagc tacaaccgct
    33661 cagaacaagt aataagcaca gcatatgctg tcacttcgga tggcgagtct aagtatatca
    33721 gaaggaggtg ctttatagca tgtacgcaat tattaaaact ggtggtaaac aagtaaaagt
    33781 tgaagtggga caagcaatct atgttgaaaa acttgacgtt gaagcaggag aaaaagttgt
    33841 ttttgacgaa gttatcttag taggcggaga atctacaaaa gtaggcgctc caactgttgc
    33901 aggtgcaact gttgaaggta ctgttgaaaa acacggcaaa caaaagaaag tcgttacttt
    33961 caaatacaaa cctaaaaaac attcacaccg taaacaaggt catcgtcaac catatacaaa
    34021 agtggttatc gacgcgatca acgcttaata gcgtttgaga aagaaggcct atatatgatc
    34081 aaaggaacat ttaagcgaaa tgacgcaggt cagatcgttt cattcacttt gaccgggcat
    34141 gctgatgctg gtccttatgg aagtgatatc gtttgtgcgg gtgtttctgc gttagcgatc
    34201 agcactgtca acgggattgc ctcattagcc ggttttgagc cgattgttga aatgaatgaa
    34261 gaagaaggcg gttatcttta taccgaagtc acttcaggaa tgacacaaga acaaaacaat
    34321 attgctgaga ttctattaga aaatctttta ttaggattac aatcgataga agctgaaaac
    34381 tcagaatata tccaaattaa aacaattaat gataaatagg aggtgcagac catgttgtta
    34441 tctatgaatc tacaattatt tgcccacaaa aaaggtggcg gttctacatc taacggccgt
    34501 gactcagaat caaaacgtct aggtgctaaa cgtgctgatg gacaaacagt tacaggtgga
    34561 tcaattcttt accgtcaacg cggtacaaaa atctatccag gtgtaaacgt gggtatcggt
    34621 ggagacgaca ctttatttgc aaaagttgat ggcgtagtac gtttcgaacg taaaggccgt
    34681 aacaaaaaac aagtgtctgt ttatccagta gctcaagaag cttaattgaa tcttatgatt
    34741 aaagaggttg tgacaagact tttgtcacag ccttttttgt ttataaaaat aaaagttgta
    34801 gtggaggcta cgaagtttac tttgtctttt tacacttaat atttttttgc caatttggaa
    34861 tcaggatgtt ttgataacta tcgttttcaa ttgatggaag ctatattgtt tgctatcagt
    34921 gaaataatta tatggtaaac agtgttcttt ttcttgtttc cattataaaa atcgtatcgg
    34981 gatttttcgt tcttttaaat tgaacatttc tatctatccg cgtgttatca acaaaacaaa
    35041 atcaggtaaa tagttgacga aacagaaata aatacatagt attatgtttt gaagcctaag
    35101 tacaatagtc tatagaaaag gagcgatacc attggcaaaa cgcattgacc gaatttatat
    35161 gtatgtcaaa gaaaaaaccg ctcatttaac aaaggcagaa tatgatcaag gagtaacaac
    35221 acaggaaatt gctgaagtgt tagggattca gcgaacaaat agcagtaaag atctgaatca
    35281 gctagtgcgc gaaggaaaac tgataaagac agacggacga ccagtacgtt acatatatca
    35341 aacactcgtt acgcacgtaa agccagttac aaaacatgta gtcagttaca aagaaacgcc
    35401 ggtctctgaa gaaaaaaata cactccaaat agatactaag gatatctttg caaaaatcat
    35461 tggagctaac ggcagcatga aaaattcagt ggaacaggca aaagctgcga ttttgtatcc
    35521 gccaagagga ttaaattgtt tgattacagg acctaccgga tcaggaaaga cttattttgc
    35581 acacgcgatg tatcattttg caaaagcgca tcatgtaata gatgaggaaa cggaactgat
    35641 tgttttcaat tgtgctgatt atgccaataa ccctgagctt ttgatgagtc atttatttgg
    35701 gtacgcaaaa ggtgctttta caggcgcaga tgaagaaaaa atggggatta tcgatcaagc
    35761 ggatggcggt atgctgtttt tggatgagat tcaccggttg ccgcctgaag gtcaagaaat
    35821 gatcttttac tttatggatc atggaactta cagtcgtctt ggggaaacaa cgaaatccca
    35881 tgaagcaaat gtacggatcg taggtgcgac cacagaagac ccaggttctt ctctattaga
    35941 aacttttgtt cggcgtatcc caatcaatat caaacttccg gcttttgaaa aacgtcctgc
    36001 aaatgagaaa gtcgatttag taaaaatcat gattgcccac gaagcaaacc gcacgcagcg
    36061 aaagatttct ttgacagaag atgtagcaaa agcattgatc ggcagtgtga cctatggaaa
    36121 tataggacaa ttgaagtcaa atatccagtt agtatgtgca cgaggatttc taaatcatat
    36181 gcaatcaccc gaaatctcga tcacaatcga tgatttgaca gaagggattc gtagcggatt
    36241 gattcaatta gcaagcaacc gcagtgcaat ggcagagctt tctaaaatat tggagccaaa
    36301 gataactgta gcaccaaatg atacgatcat gaaaatccaa tcggactcct atgagttacc
    36361 ttataatcta tatgatatca tcggagataa agcagcttta ctgaagtcgg atggtttgga
    36421 tcaagaagca atcaatcatt tcatttctac agatatcaac atccatctga agtctttcta
    36481 taaagaccat ggtttttctt ttaatgcaga cagcaaatta gcagaatttg tagatccgaa
    36541 aatcatagaa gtgaccaatc agatttatgt aatggtcaaa agatctttac catatgagtt
    36601 tcagcaaaac tttatttatg ctatgagctt gcatatcagt tcttttttga aaaaaatcaa
    36661 cttaggagaa gaacggcata cgaatgataa catccgtgag atggcttttg attttccaga
    36721 tgaatatgct gttgcgaaag aagtgcgtag ttatatcgaa acgtattttc aagtggagat
    36781 tccagaaagt gaagactatt acttgaccgt tctactcgtc tcgttacggg caaatcaagc
    36841 aagcggcaga atcggtgtag tcgttgcagc tcacggaaac agcacagcaa gcagtatggt
    36901 ccaagttgtc caacagttgt tagatgcaga gaacgtacga gcagtagaca tgcctttgga
    36961 tatggatccg aaaacagcat tggaccgaat tgaacgcaat gtacaagaag tagatgaagg
    37021 aagcggggtc atactcttag tagatatggg gtcccttgcg tcgtttaatt cgcaaattca
    37081 aagagacact ggaattccag tacgtactgt tgatatggta acaacttctc tagttttgga
    37141 aactgtacga aaggtctcag tattagggac agatctagat atgttgcatg aatcattgaa
    37201 aaattttcga ggttacgcag aaatatcttc tgtagaatct gttcaggaag caaaacctat
    37261 tcataagaaa aaagctgttt tggctatctg cgcatctggc gaaggtacag cacaaagaat
    37321 caaagaattg atcgaacgag cggtaaacaa gcgtcaagaa acagaattag aagttctagc
    37381 tttgtcgatt gtggaagtga aagaagaact gccagttatc caaaaagaat atcagatcat
    37441 agctactact gggattactg atttgaatat ccaagcccca tttattcctt tagaacgttt
    37501 tattgatcaa aatatcgaag tcattttgga tcagttgctg atggaatcag aattggagga
    37561 aactgaattc atctccctag atgaagagtc agctaaaaat acgtgtgttg agtttatctc
    37621 tgataacttc atctttatta atggtagtaa gttaatcgat ccaatgtggc aattttctac
    37681 acaaatctct cagacgacgg gaatcggcga tgaagaatat ggattcaaaa tcaacctagt
    37741 gatgcacaca gcaggaatga tcgaacgtat tattcggaat gaaccattga ctgtggaaga
    37801 aaacgaattg acaaatacaa cgaatgatcc tctttatagc caattggcag cctcagttgt
    37861 tctgttggaa gatcagataa aagtaaaagt gccgatagaa gaaatgtatt atctgctacg
    37921 tctagtccat aatcagttag ataaaaaaga atacactgtg ccatgaatac acaaaaacga
    37981 tacactttta tagtgtatcg tttttgtgta ttggttaaga atcctttaaa ttcaattagt
    38041 gtatcgtaaa aaagttggca cgctttttgc ttatagtagt gtgtgctagg aggtggttgt
    38101 tcacacagaa atgatagggg tttctgtgaa gtagtgagga agaaggagtt ttgcagatgg
    38161 atattcgatt ggcacgtata gatgatcgtt taatccacgg gcaagtcgca acagtttggt
    38221 cgaagcaaac aggtgttgaa cgtatcattg tgatcagcga tgtagtcgct caagataaat
    38281 tgagaaagtt tctactaaaa gaagctgcac cgccggggat cacagcaaat gtaataaccg
    38341 tgcagaaaat gattcaaatc tatcatagtg gattattatc acgagcaaaa gtgatgcttt
    38401 tattcaccaa tccccaagat gttgaagcgg ttgtccgctg cggtgtacag ttgaagtcgt
    38461 tgaatatcgg cggtatgagt tttactgaag gcaaatcaat gattaccaat tttgtttcag
    38521 taaatcaaca agatattgat tcctttcgtt acttgaacag tcaagaagtg gagttagaga
    38581 ttcgaaaagt acctgctgac aggaaaatcc ttttgatgga actactagcg aaaatcaaaa
    38641 aggtgtagca agaatggttg ttggaaaagg tcaaataatt ctgttgtaat ggttagcaat
    38701 tattaatatt tttgaatttg ttacaacaaa agtaaatagg aggtataaat atggtaggga
    38761 ttatcctagc aagtcatgga caatttgctg aaggaatctt acaatccggt tcaatgatct
    38821 ttggcgaaca agaaaacgtc aaagccgtga ttttgaaacc aagtgaaggt ccagatgact
    38881 tgagagccaa attggaagaa gcggttgctt cttttgataa tcaagacgaa gtgttattct
    38941 tagttgattt atggggcgga acaccgttca atcaatcaaa cacattattc gaagagcaca
    39001 aagataaatg ggcaatcgtc agcggtttga atttaccaat gttgattgaa gcctacgcat
    39061 cacgcttttc aatggaatct gctcatgaaa ttgcagcaca catcattgaa acagcaaaag
    39121 acggtgtaaa agtaaaaccg gaagaattag aaccggcaga agcaccgaaa gcagcagttg
    39181 aagacgcaca acctaaagga gcacttccag aaggaactgt ggtcggagac ggaaaaatca
    39241 aatatgtatt agcacgtgtt gactcacgtc tgttacatgg acaagttgcg acagcttgga
    39301 caaaagcagt gcaaccaaac cgtattatcg ttgtttcaga tgcagtatca aaggatgatc
    39361 tgcgtaagag actaatcgaa caagctgctc ctccaggtgt aaaagcaaat gttattccta
    39421 ttagcaaaat gatcgaagta gcaaaagacc ctcgttttgg aaataccaaa gcattgcttt
    39481 tatttgaaaa tcctgaagac gtattgacag ctgttgaagg tggcgtagac atcaaagaat
    39541 taaatgttgg gtcaatggcg cattcggtcg gtaaagtcgt tgtaagtaaa gtattgtcta
    39601 tgggacaaga agacgttgaa gcgtttgaga agcttgaaca aaaaggtgtg aaattcgatg
    39661 tacgtaaagt acctaatgat tcacgcgata acatggatga tattttgaaa aaagcaaaag
    39721 ctgaattagc aaaagcgtaa taaataatat taaaatttat aggaggctta tcatgtctat
    39781 tatttcaata attttagtcg tattagttgc ctttctagct ggtatggaag gtattcttga
    39841 tgaatttcaa tttcatcaac cactagtggc atgtacattg atcggtttag ttaccggtaa
    39901 cctcgaagct ggtatcgtac ttggcggtac gcttcagatg atcgctttag gttgggcaaa
    39961 tatcggtgcc gctgtagcac cagatgctgc attagcatca gtagcatcag caattatttt
    40021 agttttaggt ggacaaggtg ttaaaggtgt tccttctgcg atcgcgattg ccgttccttt
    40081 ggctgttgca gggttgttct taacaatgat cgtacgtaca atcgctgttc caatcgttca
    40141 tttgatggat gcggctgctg aagaaggaaa catccgtaag gttgaaatgt ggcacatcat
    40201 tgctgtatgt ttacaagggg ttcgtatcgc ggtcccagca gcagcgttgc tatttatccc
    40261 agcacaaact gtgcaatcat tccttgaatc aatgccagca tggttaacag atggtatggc
    40321 tatcggtggg ggaatggtcg tagctgtagg ttacgctttg gtaatcaaca tgatggctac
    40381 aaaagaagta tggccattct tcgttattgg tttcgttgta gctgcaattt ctcaattaac
    40441 attgattgct ctaggtgctt taggtgttgc attagctctt atttacttga acctttctaa
    40501 aatgggtggt tcatcaaata atggaggcgg aagcaactct ggtgaccctt taggcgacat
    40561 tttgaatgac tattaatctt gaaggaggaa aataaaatgg cagaagaaaa aatcaaatta
    40621 tcaaaaaaag atcgtttagc tgttgcgtgg cgctctacct tcattcaagg ttcatggaac
    40681 tacgaacgta tgcaaaacgg tggctgggca ttttctatga ttccagcaat caaaaaatta
    40741 tacaaaacaa aagaagaacg ttctgcagca ttaaaacgtc acttggaatt ctttaataca
    40801 cacccataca ttgcttctcc aattttaggg gttacattgg ctctggaaga agaacgtgcg
    40861 aatggcgcgc ctgttgatga tgtagcgatt caaggggtta aagtaggtat gatgggtcct
    40921 ttagctggtg ttggtgaccc agtgttctgg tttacagtac gtccaatgct aggtgcacta
    40981 ggtgcttcat tagctatggg aggaaatatc cttggaccaa tcatcttctt cttaggttgg
    41041 aacattattc gttgggcatt catgtggtat acacaagaat ttggctacaa agctggttct
    41101 aaaattactg atgacctttc tggcggattg ttacaagacg taacaaaagg tgcttcaatt
    41161 ttagggatgt tcgtattagc tgcccttgta caaagatggg tatcaatcaa attcttacca
    41221 gttgtatcaa ctgtaaaatt agataaaggt gcttacatcg aatgggataa attgccttca
    41281 ggtggtgaag gaatcaagag tgcatttgaa caagttaata atggcttagc cctttctcct
    41341 gaaaaggtaa caacattaca agacaactta gaccaattga ttcctggttt agctgcatta
    41401 ggattaacat tgttatgtat gtggttgctt aagaaaaagg tttctccaat cgttatcatc
    41461 cttggtttat tcgtagtcgg tgttgttgga cacgtcatcg gacttttata atccataaaa
    41521 atatagctcg ggcgttgtcc cgagcttttt ttatatagta tactgttcat aaacaaatat
    41581 ctggagggag aaaatggttc aatcaatcaa tacaaaagta gacttggtaa ttgatgctac
    41641 ttcgtttacg ggtctgacag attacgggca aatcatgata ggtaataatg gttttgagtt
    41701 ttaccatgcg cgagatagac gcaaatatat ccaaattcca tgggaagaag tggattatgt
    41761 actagcatca gtcatgctaa agggaaaatg gattcctcga tatgccattc aaacgaaaaa
    41821 aaatggtaca tacacatttt cttccaaaga acctaaaaaa gtgcttcgtg cgatcagaga
    41881 atatgtagat gaagatagaa tggtacaatc attgagtttc tttgatgtag tgaaacgtgg
    41941 tattcgtagt atgtttaaac gcaagtaaaa aataaagaaa acttctaaga ggaggttttc
    42001 tttatttttt tactttgcag aagaaaatat gaaatagcaa aaccaattat ttgtcccctt
    42061 taaatcccat atgctaaaat tgattagcaa agaaggaggt tatattatga gttggttatg
    42121 gacattgatt gttggagccg tgatcggagc aattgcaggt gcgatcacca gtaaaggaaa
    42181 ttcgatgggc tgtgtaacga atatcattgc tggactagtc ggttcaagta ttggacaagc
    42241 gattttcggc gaatggggac caaaagctgc aggtatggca cttattccat ctattttagg
    42301 cgcagtgatt ttggtagcag ttgtctcatt tttctttgga aaacgatcat aagtttttac
    42361 aaaatagtaa actaaaagga gttgcagcga gactgtgact cctttttggc tttatttatt
    42421 taaaataaaa agaagttttc cggaaatttt tatttaactg tcgtgtacga agaaaagttt
    42481 gctataatgg aaaaaagcgt gcaaagaaag agggagtttc attatgatgc tacgtgtaga
    42541 aaaattgcgc aaaaaaatgc aagaagaaaa tttggattca tttttggtta ccagtccgta
    42601 caatcttcgt tacttaacga actttacagg tacgacagga ttagctgtta ttactttgga
    42661 aaaagcattt tttattactg attttcgtta taccgagcag gcggcagcgc aggctcaagg
    42721 gtttgaaatt attaaaaatg tcggacctat ttttgatgag gtagcaaact tagtacgcaa
    42781 agaagaactg cactcattag cttttgagga aacaacagtc tcatttttag aatattcggt
    42841 tttagaagaa atcatcgatg cggaattagt acctgtttca cagatgatcg aagaactcag
    42901 agaagtgaaa gatgaagaag aaatcgctat tatcgaaaaa gcatgtcata ttgcggatat
    42961 ggcatatgat cacatcctga aaatgatcca accgggcatg actgagattg aagtcgcaaa
    43021 tcaactagac ttttatatgc gttctcttgg cgcttcaggt gtttcttttg atacgatcgt
    43081 tgctagcgga ttgcgttcgg ctatgccgca tggtgtagca agcaaaaaaa tcatcgaaca
    43141 aggtgacttg atcacattgg actttggttg ctattacgaa gggtacgttt ccgatatgac
    43201 acgtacattc gctattggtg atcctgggga aaaattaaaa gaaatttatc aaatagtctt
    43261 agatgctcaa ttagcagtta ttgatgctgc aaaaccagga atgactggtg tccaattaga
    43321 tgcagttgct agagattata tttcaaaaca tggttacggg gaagcatttg gacattctac
    43381 aggacatggg atcggtttag agatccacga aggaccaaac gtttcttctc gtgcagaaaa
    43441 gcaatttgta ccaggaaatg tgatcactga tgaaccaggg atctacttac caggaatcgg
    43501 tggagtacgt attgaggatg acttgttgat cacagaagat ggaaatcgtg tgttgactcg
    43561 ttcaccaaaa gaattgatca tcttatagtt tcatcaatag aagaagtaag cgtaaaaatc
    43621 agtgttcaca gactttgtta tagaaaatca ctcgatttaa tgatacacta tagaagaact
    43681 tttaagctgt aagagataat aaagttgggt gttttctcca attcatagca gtttgcagct
    43741 gatcggcggc agttttctta ccacgtgatc actatgccgc atcatagaga attcggatgt
    43801 atctcgtgct taggcaaagg gaggaataaa taaatggcag atgaaaaaaa tttgatttta
    43861 aacgcaaacc aagatttagg agagatcgtg atcgctcctg aagtcatcga agtaattatc
    43921 gggattgcag cttctaaagt agaaggcgta tacggaatgc gcggaacttt tgccagcaat
    43981 gtcactgaat tattaggacg tgcagctcac ggaaaaggtg tttacttagc aaacgaggaa
    44041 gatggcttga aagtagatct ttactgttat ctagaatatg gtgtttcagt tcctaaagta
    44101 gcaatggaaa tgcaggaacg ggtcagccag caagtccttt tcatgacgga tatcgattta
    44161 tctgaagtca atatccatgt agtagctgtt gttcctgaaa aattagaaca accaacaatc
    44221 gaagaacttt ttgaagacga agaggaagag aatgaataaa gaattatcaa gacacgagat
    44281 tcgggaaatg gcattgcagg ctttatttcc attagacttc aatgcagacc taacaaaaga
    44341 agatgcgatt ttcaacgcaa tcgaattaga ccaccgcgac atgatcaacg aagatgaatc
    44401 agagtttgtt cctgtttatc ttgatacgct agttggcggt gtctgtgcaa aaaaagatga
    44461 attggataaa gtgattgaaa aacatttaaa aaacaattgg cacatcaatc ggatctcaaa
    44521 aatggatttg gtgatcttgc gtatcgcgat ttttgaaatg acttatgtga cagatgtacc
    44581 agcggctgtt gctttaaatg aagcaatcga gttggcaaaa acatttagtg atgaccgttc
    44641 acgtaaattc gtcaacggtg ttttatccaa tgtattgaaa gaattagaag ctggggcgta
    44701 agtcctagct tttttctatg aatcatcata aacctgttat aaatcgggaa aattctatgg
    44761 tagaatgaaa acacaaaaaa tatctgggag tggttagatg gcagaattga ttaacggaaa
    44821 agaattagct gaaaaaatgc aggcagagat tgctgaaaaa atccaaaaat tgaaagataa
    44881 tggtatccat cccggattag tcgttttatt ggtaggggaa aatccagcca gccaaatcta
    44941 tgtaagaaat aaagaacgtg tagcaaaaga aatcggaatc cattcattgg tagagcgtta
    45001 tcctgagacg atttctgaag acgaactact tgcagaaatt gaaaaataca atcaagatcc
    45061 tagttttcat ggtatattgg tccaattacc attgccaaag catatagatg aagaaaagat
    45121 cctgttagct atccgccctg aaaaagacgt agacggtttt catccgatga atttaggcag
    45181 actccttgcg ggtaaaccgg acaagattcc ttgtactcca tacggcatca tgaaaatgtt
    45241 tgaagcttat tctatcgatc cggcgggtaa acgagcagta gttatcggac gaagcaatat
    45301 cgtcggtaaa ccgatggctc agctactctt gatggcagat gcaactgtta ctgttgctca
    45361 ttctaaaacc gaaaatctgg ctgaactggc acaagaagca gatattttag tcgtagcaat
    45421 aggacgtgga cattttgtca caaaagaatt cgtaaaacca ggtgctgtag tgatagatgt
    45481 agggatgaat cgtgatgcta acggtaagct gatcggtgat gtgaaatttg atgaagtgga
    45541 gcctattgca ggctggatca ctcctgtgcc aaagggtgta gggccaatga ctatcacgat
    45601 gctgatgtat caaaccgtaa aatctgccga agcttttgga gcaggtgaat agatggcaca
    45661 agaatattta actgtcacta cattaacgaa gtatttgaaa agaaaatttg atgccgatcc
    45721 ttatttagaa cgcgtatatt taacaggcga aatatcgaat ttccgtttac gtgccaatgc
    45781 ccatcaatat ttcagcttaa aagatgacca tgcaaaaata tctgctatta tgttcaaagg
    45841 agcattccaa aaattacgat tccagccaaa agaaggaatg aaagtccttg tcgttgggcg
    45901 tatttcatta tatgaagcgg gaggttctta tcaaatctat gtagagcaca tggagcctga
    45961 tggaataggt gctttatatc aagaattgga agaacgaaaa gaaaagctga tgaaggaagg
    46021 cctttttcaa gggcctaaaa aaatgctgcc acgtttccca aagcgaatcg cggtccttac
    46081 cagtccaagc ggagcggtta tccgcgatat catcacgacg gtgaaaagaa gatatccaat
    46141 tgtccaattg gttttgttcc caacagttgt acaaggaaac caagcagcgg acaatgttgt
    46201 caggaatatc cagagagtag aagagatggg caatttcgat acaatgatca tcggtcgtgg
    46261 gggtggttcg attgaggatt tatggccgtt taatgaagag cgggttgctc gggcgattta
    46321 tcaagctaat acgccggtga tttcatctgt aggacatgaa acagatacca cgatcgctga
    46381 tttagtagca gatgttcggg ctgccactcc aacagcagct gcagaattag ctgttcctgt
    46441 tttgtcagaa gagttgatgc gcattcaaga acggcaagct agattgcagc aggcgtttgt
    46501 acgccagatc cagcgcaaac aagaacggtt cgagcgtgct cgacgttcct atgtatttcg
    46561 gcagcctgaa agattgtatg aaggtcagac catcaaatta gaccagttga aacagcgatt
    46621 atatcaagct acacagcaaa tttatcatgc gaaagaaaaa caaacgatcg cattaagcca
    46681 ccaattggaa caagtggctc cgctttatcg agttaaagca gctcgccaag aaactgctta
    46741 tctagaaaaa cgcttagaag agaaaatcca acaatatatg aaacaacagc agcagcgttt
    46801 tgctcaagct gttcaatctc ttgatttgtt gagtccattg aaaatcatgg gaagaggcta
    46861 cagctatacg acgttaaatg atcaagtagt aaaaagtgtc accgagattc atcaagggga
    46921 tttgctgacg atccattatc aagatggaat cgttaaagga caagtacaag agatagacaa
    46981 aggagaataa aaatatggaa aatccaactt ttgaagagtc actgcaagaa ttagaaaaaa
    47041 ttgtcatgca gttagaacaa ggagacgttc cattagaatc agctctagat tcgtttaaac
    47101 gaggaatgga attaagcaaa cattgccaag atacattagc taaagcagaa gagaccttga
    47161 cgaaaatgat gacagaatca aatgaagaag ttgattttga cggaaacgag gaaagctgag
    47221 atgagattaa ctgacttttc agctattcat ctacctgctg tagaaaaaga aatcttgtct
    47281 tttttagatg agcatacaac ggatagagga ctctatgatg cgatgagtta ttcagtgaaa
    47341 gcaggcggga aaagaatacg tcccttatta cttttaacgg ccgttgcttc ctttgatgag
    47401 cctattgatg ttcccgtcta tcaagtagca gctgctttag aaatggtgca tacgtattcc
    47461 ttgatccacg atgatttgcc tgcgatggac aatgatgatc ttcgtagagg aaaacctacc
    47521 aatcataaag tattcggcga agcattagct atattggccg gagatggttt gcttacagga
    47581 gcattccagc taatcagtat ggcacactta ggtaattctc ctaagcttct gctgcttcag
    47641 caattagctg tttgtgcggg atcacaaggt atggttgctg ggcaagctgc agatatcgag
    47701 ggcgaatcga aaaagctttc tttagaagaa ttagcattta ttcatgaaag aaagacaggg
    47761 catttgattc gttatgcctt gctggctggt ggcatattag cgaagcaacc tgaagaaatc
    47821 ttattgctac ttcaacgatt agccgaacat ttaggtttag cttttcagat aagagatgat
    47881 ctactcgatg tgattggtac aacgaaaaca ttagggaaaa cagctggtaa agatgaacgt
    47941 atggaaaaaa atacttaccc gcgtttatta ggcctagaaa agacacgtga ggcgttggag
    48001 attgagctgt tatccgccaa caagatcata gacaaattag aagaggacgt tttttctttt
    48061 gatggcgggc tgatgcgcca gatgatcaag caatttgatg tggagaaatg agggaaagaa
    48121 tggaaaaaga acgcgtagat gtattagcgg tcaaacaagg attatttgaa acaagagaac
    48181 aagccaaacg ttcagtgatg gctggtttga tttacaacga aaaaaacgag cggtttgata
    48241 aaccgggaga aaaaattcca gtgagtagtg aattaagagt caaaggtaaa aaacttcctt
    48301 atgtttctcg agggggatta aaattagaaa aagcactcaa agcatttgat ctatctgttg
    48361 aaggaaaaac attgttagat attggtgcat ccactggcgg atttactgat gcagctttgc
    48421 aaaatggcgc aaaaatgagt tatgctttag acgttggcta caatcagcta gcttggaaaa
    48481 taagacaaga tcctagagtc gtcgtaatgg aaagagtgaa ttttcgttat gcaaaacccg
    48541 aagactttac cttaggaatt ccagaagttg ctgttatcga tgtttctttt atttcactaa
    48601 aactgatgct gcctccatta catgctattt taaaagaaga gggagaagtg attgctttaa
    48661 tcaaacccca attcgaagca ggcagagaag ctgtagggaa aaacggaatt gttcgtgacc
    48721 ctcagaccca tcaaaaagtt ttagaagaca ttttgtcatt tgcggcacaa ggtggatatg
    48781 atgtgctgga attaagttat tctccgatca cggggggaga aggaaatatc gagttcttgg
    48841 ctcacttgag gaaagtaccc gaaagcggaa caatcaattc agctattaat atggcagaag
    48901 tggtttcaaa tgcacacgaa cagtttgacc ataaataaat tgtaactgtg aaaatcaagt
    48961 gagaagtatg cggattcttc tttattatac caaggaaata agctatcatt gattaagaag
    49021 aatatgctaa ggagcgaaga cgtaatgaga aaaaaagatc ggcatcgttt gattactcga
    49081 ttgttgagtg agcaagatat ccgaaagcag gaagaatttg ttgaaatcct gaaaagcaaa
    49141 ggaatatctg ttactcaagc tacgatttcc agagatataa aggaactgaa actgatcaag
    49201 gtaccggctt cagatggcgg ctaccgttat agcataccag ctgaaacaaa cgaagatgta
    49261 aatactaaat tggaaaaact attaaaagac gctttcgtgg cagttgacca aatggaaaaa
    49321 tttgttattt tgaaaacatt gccgggaaat gcttcggcag cagcaaattt gattgataaa
    49381 cgttacaaga aagaattatt ttcgattatc aatgatgacg ataatgtttt gatgattaca
    49441 cgaactgaag accaggcagt tttattgaag aaagacttcc tgcattacct ttaagttgag
    49501 gagcgaatgt gatgctacaa gaaatcagta ttactaactt tgcgattatt ccggaattgc
    49561 ggctttcttt tcacgaagga atgaccgcgc tgaccggaga gactggtgcg ggtaaatcca
    49621 ttattatcga tgctttaggt ctgttagcag gaggaagagg ttcaagcgat tatatacgtc
    49681 aaggagcaga aaaatgtgtg cttgaagggt tgtttgaact accaaaacaa gaaggattct
    49741 ctgaactgat ggttgaatta gggatcgaaa cagatgagga caatctgatt gttcgacggg
    49801 atatgtcctt aactggaaaa aatgtttgtc gagtgaatgg tcatattatc acattagcta
    49861 atctgagaag aatcggcagt tatttagtag atatccaagg acaaaacgaa catcaggaac
    49921 tgctccagcc tgaatcacat cttgctttat tggatcgttt tggagatgta gctttccaac
    49981 agaagaaaaa gagttatcag caagaatata tctcttatcg tgagctggaa aaaagggtac
    50041 gaaaagtgca gcaaaatgaa aaatcctatg ttcagagaat agatatgctc catttccagc
    50101 aagaagaaat agctgctgct gatttgcaag tcggagaaga agagaaatta aaagaagaaa
    50161 gagaaaaact tagcaattat caaaaaattg ctgatggatt agctgcaggt tacggagcac
    50221 tgacgaataa tgaacaaaac agtgtagatg gtgttggctt ggccgtttca gaactgcaag
    50281 ggatcgccca tctagatgtg gagtatgaag caatttatga aaatatccaa agtgcttact
    50341 atttgctgca agatgcaatc ggcgatatga gtcgtcagat tgatttattg gagttagatg
    50401 agagtcgttt agaagaagtt acgcaacgtt tagaattaat ccgacagttg aaacgtaaat
    50461 acggcgaatc cattgagtca atattggctt actatgacga aatcaccgaa gagctagctt
    50521 cttctgattt ttcagaaggt caattggaca aaatgaaaga ggaactagag caaaaagagc
    50581 ttctacttca gcaacaagcc gcagatcttc atgaagcgcg taaaaaaatc gcaaaagaat
    50641 tggaaaaatc cattctgcat gaattgaaaa gtctgtatat ggaaaacact gagtttgagg
    50701 tacgtttctt aaaagaagaa aatagacaat tgaatcatga tggatttgac caaatcgaat
    50761 tttacattac gaccaatcca ggagagccac tgaagccttt ggtgaaagtc gcttctggtg
    50821 gcgaactgtc tcggatgttg cttgctttga aaactatttt ttcttctgag caaggtgtga
    50881 caagtattat ttttgatgaa gtggatacag gtgtgagcgg aagagttgca caggccatcg
    50941 cagataaaat ttctcaaata tcgaaatact ctcaagtttt gtgcatcact catctgcctc
    51001 aagttgctgc agtcgccgac tatcaatatt atattgtgaa agcagtgatt gatggacgta
    51061 cgcaaacttc tgtttcagag ttgaaaacaa aagaaagaga agaagaaatt gcacgtatgc
    51121 tggctggaag tgagattaca aaactcacac tcgaacatgc aaaagaacta ttgaaactcg
    51181 caaaaaggac ctgagccacc tcgcagtggt tcaggtcctt ttcagcagct gatagctata
    51241 ttttattttt acatgacact cattacagca gtcaatacaa cagatccaat cgttaaaatc
    51301 agcattgtcc aaatgacaaa ttttgttact ttagcaaaag tacttgtttg ttttttttca
    51361 cgcattgttt tcaacctcgt cattaattag ttgattcaag tgtacaatct tttttccatt
    51421 tccacaagag ggctttttta taaaaacttc ccttttttta aataataggt agttacgata
    51481 caaataaata atgttaatag aactagccat ataaaggcat catccctttc agcaataggt
    51541 aacttaatgt tcattccata gatactgccg acgattgtcg gtatagttaa aataatcgtt
    51601 aaagaagtta aaattttcat aatattattc agattattcg atacgattgc tgaaaaagtc
    51661 tgattcattt gttctactag ttttaattga atgcgagaag tagtcattgc ctgctctgtt
    51721 tccaccaata catcacgtaa atgatttttc aaagcatgat tttcttggaa aagtttattt
    51781 tgcgctagtt ctttcaatgc atctaaatta gcagaagtcg cttctctgaa ataaacgagg
    51841 cttttttgga tatccatgat ttgataaagt tgtttgtttt cagtggatac ttgaagtttg
    51901 gcttccaaag tatcgcattg agattgaagc gtagctaaat aactgttgta agagagtgtg
    51961 acctgccaaa tgaattgaaa gaagatattg agattaggcg aaatatcact ttttggaaag
    52021 gtctggctaa agactttctt taaaaacagt ggttcatgat tcgtaattgt gataagcttc
    52081 tttttgggcg tcaaaataat agagagcggg tatgtatcca cttgaaaata accgctagga
    52141 cttgttttag caaaaggata ttgtaacaat aataacgctg gctttgtcaa ctttgattga
    52201 ttgaattctt ctgtacggga attttctgca tcgtccaata tggaagtgat gtaatctgac
    52261 ggaatttcaa attgatgtgt cagctgatga atctcttctt gattaggacg ttctacacaa
    52321 taccagatcg tttggtcagt ttcctttccg gtattacgca gtttctcatt atctaatgta
    52381 aaatatttga tcatgatttt cctcctgttg cctgtttctt ttattataac ggatagggaa
    52441 ttggaataca tggaatgtgt ttgtaagata tagaatataa ctgcataaat ttaaataaaa
    52501 tgaaacagtt gtgtaaagta tatacagtat acttgaagca acgataaaaa aggagtttac
    52561 gttcatgggc acattcacac cacttatctt gttttggtat atttacccgg taatcgtttt
    52621 gtttggttgc caatttcttg taaaattatt ttcgttaaat cgtcgtttta aaataaaagc
    52681 ccctgatttg gcgattcctt ttttgtgggg cggtatgcat gcattgtcta gaaatacagg
    52741 gacaatttct atcttaccgt ttttctttat ttctgttttg ctaatgggaa tttgtattgc
    52801 tgttttccaa gcatattatt atgaagaaat tatttatccg cgttatttca agatgacttg
    52861 gcgtttggtt tttctgttga caatcgtctt gtacgctgtc ttgatcattg tgaacatact
    52921 ttcttaccta tgaaaaaaat agaaaagctg taaaaagtct tttaaaaggc tttttgcagc
    52981 ttgattttta aaaaaatgtt tatgaataaa aaaagttgtt cccggatttc ccagaaaagg
    53041 tggtagaaag tgggggattg tggtagacta attttagtta gtggaggaat ggggggcttt
    53101 caatgttgat gggtgaattc caacataata ttgatgcaaa aggacgttta atcgtgccct
    53161 caaaacttcg tgaagaactt ggcgaaaagt ttgttctgac acgcggattg gatggctgtc
    53221 ttttcggcta tccgatgagc gaatgggaaa atctggaagc taaactgaac gaaatgccgt
    53281 tggctaaaaa agacgcacgt acttttgtgc gattcttcta ttcggctgcc actgaatgcg
    53341 aacttgataa acaaggacga atcaatatac ccagcacgtt aagaaattat gcagctttga
    53401 caaaaggttg cgtagtcatc ggtgtatcta accgaattga aatttgggat gagacacgat
    53461 ggcaagattt ttctgcagca gcagaagaga actttgacga aattgctgaa agtatgattg
    53521 atttcggact ataagaatag gaagaggctg actaatgact gaaacatttc aacactatac
    53581 agtcatgttg aaagaaacgg tagatggatt gaacatcaaa ccggatggcg tttatgtaga
    53641 ctgtacactc ggcggtgccg gacatagtga atatttatta agccaactaa gttctaaagg
    53701 gcatctgtat gcgtttgacc aagatcaaaa agcaatcgat cacgccaagc tgcgtttagc
    53761 ttcttatgtc gaacaaggta tggtcacatt tatcaaagcg aacttcagag aattagaaga
    53821 acgcttgagt gagcatgtag ataaggtaga cggcattttg tatgatctag gggtttcctc
    53881 tcctcagcta gatgaagcag aacgtggatt tagttatcat caagatgcac cgttggatat
    53941 gcgcatggat cagtcagctc ctttatccgc ttatcacgta attaatgaat attcctacca
    54001 tgaattagta aagattttct tccgctatgg cgaggagaaa ttttccaaac aaattgctcg
    54061 tgaaatcgaa cgagtacgaa aaacaaaacc aatccaaaca actggtgagc ttgtcgaaat
    54121 cattaaacaa gtcatcccag ctcccgcaag aagaaaaggc gggcatcctg caaaaagaat
    54181 ttttcaagct gtgcggattg cagtaaatga cgaactcggt gccgaagagg cctctttaga
    54241 acaggcaatc cggttattga aagtcaatgg aagaatcagc gtaatcacat tccattcatt
    54301 ggaagacaga attgtcaaaa gtatgtttaa agaatatagt acggtacaag atctaccacc
    54361 gggacttcct gtcatacctg acgaattcca accagaactg aaagtcatta ctcgtaaacc
    54421 aatccttcct tcagaggaag agctaacaga aaacaatcga tcacgcagtg caaagttacg
    54481 tattgcagaa aaaataagaa tgaaagagga gtagaatgat ggcagaatta aagaaaatgc
    54541 aagattacga atatgattta cctgaattgg tggatcagcc ggaacaacaa atgcctgatt
    54601 cttcttcgaa tcaagaaatc attcttccac aatcaccggc aaaacgatta aagcagattt
    54661 ctgctttgga aaaaattgct gtggcaagcg tggcgattgc tattgttgct ttatgtgttt
    54721 taacagttat gctgcgcaca aatatcagcg gagctgaaaa agaaatcacg tcaatacaaa
    54781 cagaaatcaa tgataaaaag caagaaaaaa cgagtttaga acaagaaaaa aacgaacttt
    54841 ctcgtactga acggattaaa caaatcgcag aagaaaaagg attgtctatt aatgacgaca
    54901 atttaaggaa agtgaagtaa atgagtctta aaaataaaat tcggcggttt atggaaaaga
    54961 aaaatctaaa tccgatgaac aatcgcaaaa aagtaggtat cattttattt gctacgagta
    55021 ttggattgtt ctttttattt gccgtccgtt tctcgtatat cgttattgga ggtcatgttg
    55081 ctggtacctc attagctgaa aaaacaaaac agttgtacca aggaagtgaa gtagtaaaag
    55141 caaaaagagg aacgatttat gatcgtaacg gtgtggcgct cgcagaagat gcctcctctt
    55201 attcaattaa agcgatactc tcaaaaacat atacctctgg ggataaaaaa ctgtatgttg
    55261 aagaaaagaa ttttgataaa atagcagaaa tcctgcataa gaatctttct atagacaaaa
    55321 aagatgcact gaatatttta gaggacggcg caaaaaaaga gctgtatcaa gttgaatttg
    55381 gtagctatgg gaaaaatatc tcccaagaaa ccaagcaaaa catcgaagcg gacatgaaaa
    55441 aagaaggtgt cgctggtctt tattttgtcg accatcaggc tcggatgtat ccaaatggcg
    55501 tcttttcttc tcattttatt ggatacgcag ttccagacaa agatgagaat ggcttagttg
    55561 gtaaactagg tttggagtct gcttacaatg atatcttgag cggtaaagat ggtaagatta
    55621 tttatcaaaa agataatttt caaaatcctc tgccaggtac agtggcagaa gaagaaaaag
    55681 ctgtcgacgg acaagatatc tacacgactt tagacagcag actacaaagt tatttagaaa
    55741 cactgatgga tcaagtaaat gaagaatatc agccagaaga attgacagca gtcctgatga
    55801 aagcaaaaac cggagaaatc ttggcaatgg gacaacgacc tactttcaat cctgaaacaa
    55861 tggaaggatt gactggaaaa gatgctatct ggcgtaattt cttggtacaa gatagttatg
    55921 aaccaggatc aaccatgaaa gttttcacta ctgcagctgc tatcgaagaa ggagaattca
    55981 acgagaatga aaccttccaa tctggaaaaa tccaagtaga agatgctacg atcaatgacc
    56041 atgactttgg tgaaaaaggt gtgctgacca tgcgtcaagc tctttcatgg tcaagtaacg
    56101 tcgggatggt catactggaa cagcgattag gcggacgatg gtataactat ttacaaaaac
    56161 tgggatttgg acaaagtact cattctggat tagatgatga agtaaacggt gctttaccta
    56221 cattaaatat tgtcgaccga gcaatgagtg cttatggaca agcggtaggt gtgacgaatt
    56281 tccaaatgat gaaagctttc acttctattg cgaataacgg tacaatgatt caacctcgat
    56341 atatcagcaa agtggtggat ccccaaactg gagaagagcg aacaactcaa acagaagttc
    56401 tagggcaacc tttttcaaaa gaaacaacag aaaaagtccg tgaatatatg agagatgttg
    56461 tcgaaagcga aaactacggt agtgcttatg gtgtatatag tgtacctgga tacaatgtat
    56521 cggcaaaaaa cggaacagcc caaatcgctt ctgatacagg gggatatcaa acaggagata
    56581 cagcctacct gtattcgatt gtggagatgg ttccttctga agatccagac tatgtcttgt
    56641 atctaacaat gaaacaccct aagacatatg atcgaatggc attggctaaa atcgcaaatc
    56701 cattgatgaa acgggcaatg gattttaaag aaactgaaga agattcagat acagaaacaa
    56761 aaacagaaaa agtatccgta gccgattatc gtaatcttga agcggacgtt gcagcagctg
    56821 atgctcaaaa aagtggactg caacctgtag tgatcggtaa tggtaaaaaa gtacaaaaac
    56881 aatctactgc caacggtgat cagttgatct ctggagaaaa actgatccta tatactggtg
    56941 gtgataagct gatgcctgac gtaacaggat ggtcaaaagc agatatcatg aagctgggga
    57001 aaatcctcgg tattgaagtt agttttgatg gagatggtta ttgtgtcaaa caagaacttg
    57061 ctccatatga aaaaatcact gaagacaaac ttagttttac tttagaagaa taagaagaga
    57121 aataggagag aaaagagcat ggaatggaca caagcattga ttcccattgt cagcagttgt
    57181 gcaatgacaa ttgccgcaat gccgctattt attggttatt ttcaaatgaa aaagcaaggt
    57241 caggcgattc gtgaggaggg accaaagtgg cacaatagca aagccggaac tcctacaatg
    57301 ggcggcttag tgtttctgat cggctctatt ttgacaggaa tttgggttgg agcttggcaa
    57361 aaacagctaa ctcctactct tttcatcttg ctttttgtat tagcgttata cggagtaatc
    57421 ggctttcttg atgattttat aaaaatattc aagaaaagaa acatgggact gaactcgaag
    57481 cagaaattga ttggacagat tctaggggga atcatctttt atcttgttta ccgttctgaa
    57541 ggttatccag gtgtattgaa tttcttcgga ctagatctac ctttaggaat catttatggt
    57601 attttcgctc tcttctggct tgttggattt tcaaatgcag taaatctgac agatggcatc
    57661 gatggattag ttgctggctt aggaagtatc tcttttgcag cttacggtct aattgcttgg
    57721 catcagcatc agtatgatgt attaatcatt tgcttaagtg ttttaggagg tttactgggt
    57781 ttcttcgtct acaacagaaa acctgccaag atttttatgg gagatgtcgg ttcattagcg
    57841 ttgggcggac ttttagcggc aatttctata atgctaaacc aagaatggac attgcttttg
    57901 attggtttga tctatgttat ggaaacagca agtgtgatgc ttcaagttac ttcctttaag
    57961 cttacaggaa aacgaatttt taaaatgtct ccaattcatc atcactttga aatgtgcgga
    58021 tggtcggagt ggaagattga tacagttttt tggttgatca gcattgtgac ttcgttgatc
    58081 acattatgga tcgtttggta ggagatgacg ggaaatgaaa aaaatatcaa catatgaaaa
    58141 taagaaagtg cttgtcttag gactcgcaaa aagcggagta agtgcggcca aattattaca
    58201 tgaattgggc gcacttgtca ccgttaatga tggaaaacct tttgacgaaa atccggaagc
    58261 acaagagctg ctttctttag ggataaaagt aataacaggt agtcatccaa tcgaattgtt
    58321 ggatgaagaa ttttcattga tggtcaaaaa tccagggatt ccctacagtc atcctttagt
    58381 agcaaaagcc caagaaatgg gtattccggt aattacggaa gttgagctag cttacgaagt
    58441 agcggaatgc ccaattattg ggattacagg aacgaacgga aaaacaacga caacaacgat
    58501 gacaggacta ctactgaatg caggagcaga tcaaggaatt gcacgtttag cgggtaatat
    58561 tgggtatcca gcaagtggtg tagcgcaaga agcaaaatca gaagataaaa ttgtgatgga
    58621 attgtctagc ttccaactca tgggaatcac agatttccgc cctcatatag cggtgattac
    58681 caatatctat gaagcacata ttgattatca tggtacaaga aaagaatatg tcaaagctaa
    58741 atggaacctt caaaaaaaca tgacagaaaa agattatctg atccttaact ggaatcagtc
    58801 agaactacaa gaattagcgc aaagaacaaa agcacgcgta ctgcctttct cgacaaaaga
    58861 agtgttggaa gacggtgtgt atgctgacga ttactcaata tactataaaa aagaaaaaat
    58921 aatggaaata tctgaacttg gcgtaccagg taagcataat gtagaaaatg cactagctgc
    58981 tatttctgta gcaaaattgt atggtatatc aaatgaagct atacgagaaa cgttgcattt
    59041 tttccatggc gtaccacatc gtacgcaata tgtaggagaa atccaaggca gaaaatttta
    59101 taatgattca aaagcaacca atattttagc gactaaaatg gctctaagtg gatttgaaac
    59161 gtctaaggtc gtgttattgg ctggcggatt agacagagga aatacatttg atgaattaat
    59221 tccttcatta aaaggaatca aagcaatggt cgtatttggc caaacaaaag aaaagttgat
    59281 ggatgctgga aaaaaagcag gcatcgagac aatagtaaca gccgattctg tagaacaagc
    59341 agttccttta gcattagaaa acagtacaga tggtgatgta gttttattat caccagcgaa
    59401 tgccagctgg gatcaatacc caaattttga aactagagga aacagattca tggaagctgt
    59461 gaaccgatta aaatagaaaa agtagaagcg agcgataaaa aatgaaaatt ttggttacag
    59521 gcggaggaac agggggacat atttatccag ctcttgcctt tgtcaattat gtaaagactc
    59581 aagaaccgaa tgctgaattc atgtatgtgg gagcaaaacg aggtctagaa aacaaaatcg
    59641 tccctgatac aggaatgcct ttccatacct tggagattca aggatttaaa cgaaaaattt
    59701 ccatgcataa catcaagacg gtccgattgt ttcttaagag tatccgtcaa gcaaaaaaaa
    59761 tcctcagtga ttttcaacca gatatcgtta tcggtactgg aggatatgtt tccggagcgg
    59821 tagtgtacgc tgcagccaaa atgggtattc caacagttat ccatgaacaa aacagtgtac
    59881 caggtgttac caataaattt ttaagccgat atgtggatcg gatcgctctt tcatttaaag
    59941 atgcggcttc cttttttcct gaaaacaaag cagttcttgt aggtaatcct cgagcacaag
    60001 aagtagcaga tactaaaaaa tcagatattt tgaaaacatt tgatttggat ccagaaaaga
    60061 aaacagtctt gatttttggc ggtagtcaag gagcacttaa aatcaatcaa gcagtatcag
    60121 tttttttaag tgaatatatt ccttcttctt accaagtttt gtatgcttca ggagatagat
    60181 attatgaaga gatcctaaat aaaataaatc ctgaaataca aaatattagt gtccagcctt
    60241 atatcaaaaa tatggcagag gtcatggctt ccagtgatct gctggtgggg cgtgctggtg
    60301 caacttcgat cgcagaattc acagctctgg ggttaccggc agtgttggtt cccagcccat
    60361 atgttacgaa tgatcatcag actaaaaatg caatgagtct tgttcacgca ggagcagcaa
    60421 aaatgattgc agataatgaa ctaacaggtg aatcactaag tcagacagtc aacgaaatca
    60481 tgggtgatga agaattgcaa aagcaaatgt gccgagcttc taaagaacaa ggaatccctg
    60541 atgcttcaaa acgtctttat gacttagtaa aacaaataat caaaaaataa aggcggtggt
    60601 cttagtgagt aagaaaaaag aaccaaaaaa attgtctcat ccgtcttctg atgaaaacaa
    60661 tttgactcct tggcaaaagg ctaaccgaaa atatctggca gaacaagaga tgaaaaacca
    60721 agagccaaaa aaagaagaca taacattaga tacacccctt tcagattctg aagaagaaaa
    60781 aacggttcaa gaggaacagc aagaagaaag ccagtccgag aaaaaaatcg aattttttga
    60841 agagatcaag caaaagaaaa acggtggacc atataacggt tcttttttga accggctgcc
    60901 caatttaaaa agtcaacggc acaaagtact atttcgtcgg ttagctttga tcatcactgt
    60961 attgggtata ccgctgattt ttttgatcta ttatgtttct ccttatagca aattacaagc
    61021 agttgcagta tcaggcaata agacagtcaa cagccaagaa atcatctctg atacaaaatt
    61081 gtcattagga gaaaatgttt ggggacagta ttttcatcga tctacttata tcgatcgcct
    61141 taaaaaagca cagccaagaa tcgaaacagc aaatatacat ttcaaaggga tgaatgaatt
    61201 cgatttggat gtaacagaat ataaagagat tgctttgatc gcaaaaaaca atcaatacta
    61261 cccagtgatt gaaaatggaa cagtattaga tgaaaaagta gcaaatccta caaaaaatct
    61321 ccctatcttg gaagagttca aagactctgc aaaaatcaaa gaattaacaa agcaatacaa
    61381 tcagttatca tcagaattac aaaaagcaat ttctgaaatc aagtacacgc caagagcaag
    61441 caataaaaat ctgatccaat tgaatatgaa tgacggcaat caagttattg taaatatcaa
    61501 taatcttgcg aaccaaatga aatattattc gcaagtagcc aaagatatgg atgaaaaagg
    61561 tgtgatcgac atggaagttg gtatcttctc gcatccttac ggtagcactc aagaaacgga
    61621 agaatcgggc caatcggaag aaacaactga aagtgaagaa aatgcggatc aaacaaacga
    61681 atcaagtgaa gaggcagaaa cgcaaaaagc acaaacacct ggatcgtcta gcacaaacgg
    61741 atcatctgat tcaaatgatt caagtgaaac aagtcaaata gaagataatc caagtacaac
    61801 tccgtcaagt ttaaatgaaa attgataaaa caactttaaa aagtaagaat gtactttcta
    61861 aaaaccagta atttatggta gaattggaag cagtgaatat atctattaat aagtatattt
    61921 taaaacggac gctagttgtt cgcttgtata tggaatagta agtaggaggg aatcccattc
    61981 atggcaaaaa caggaatgta tgtaggcctt gatattggaa cgacatctgt taaagttgtc
    62041 gtggctgaat atatcgacag ccaaatgaat attattggag taggaaacgc aaaatcagaa
    62101 gggattaacc gaggcattat cgttgatatc gataaaacgg tccaagcgat acaacgagca
    62161 gtacgacaag cagaagaaaa agcaggtatc cagatcaaag gcgtaagtgt cggtttgcca
    62221 gcaaacatgc ttgaagtaga aaattgccag ggaatgattg cagttaacgg agattcaaag
    62281 gaaatcaccg atgaagatgt cagaaatgtg gcttcagctg cccttgttcg ttcaatacct
    62341 cctgaacgtc aaatcgtgtc aatattgcca caagatttta ctgtcgatgg gttcgaggga
    62401 atcaaagatc ctcgtggaat gatcggcgta agattagaaa tgtacggtct gttgtttaca
    62461 ggacctaaaa cgatcatcca taacatacgt aaatgcgtgg aaaatgccgg attaatcgtc
    62521 aacgaaatgg tgattactcc tttagcgctg actgaatcaa ttctttctga cggagaaaaa
    62581 gattttggta cgatcgtcat tgatatgggt ggcggccaaa caacaacggc tgttatgcat
    62641 gataagcaat tgaagtttac caatcttgac caagaaggtg gcgaatttgt cactaaagat
    62701 atctctattg tattaaatac gtcatttaac aatgcagaag cgttgaaaat aaactacggg
    62761 gatgcatacc cagaacggac atcaccagat gaagaatttc cagtagatgt gattggtcag
    62821 tcagaaccag tgaaagtcga tgaacgctac ttgtcagaaa ttatttcagc tcgaatggaa
    62881 cagattttca acaaagcaaa agatgcattg gaccaaatcg aagcattaga gttgccaggt
    62941 ggcgtcgtat tgacaggcgg agctgctagt cttcctggtg ttgtggactt ggcacaagaa
    63001 atcttcggcg taaatgtaaa attgtatgtt ccaaatcaca tggggctgag aaacccggta
    63061 tttacaaatg taataagtat cgtggattat tcagcaaact tgagtgaagt gtatcaattg
    63121 gcaaaaattg ctgttacggg tgaaacctca gcagctcgtc aaatggtagt tgaacaagaa
    63181 acaacaaaca catatgagag ctatgaagca cctgaagaaa caatctacga tgagccggaa
    63241 ccaaaagagt ccggagaaaa tgtaaaaaat aaaatcaagg gtttctttac aaatattttt
    63301 gattaattca tcctgggagg aataagatat ggaattctca attgataata atatcaatga
    63361 cggcgcagta atcaaagtca tcggagtcgg tggtggcggt ggaaatgctg taaaccgaat
    63421 gattgaagaa aacgttaaag gtgttgaatt cattacagcc aacacagacg tgcaagcatt
    63481 aaaaaattca aaagctgaaa cagttatcca attaggcccc aaatatactc gtggtttagg
    63541 tgctggttct cagccagaag ttggacaaaa agcggcagaa gaaagtgaac aatccttacg
    63601 cgaagcttta gacggtgcag atatgatttt catcactgca ggaatgggtg gaggaaccgg
    63661 tacaggtgct gcaccaatcg ttgcaggtat cgcgaaagaa ttgggcgcat tgactgttgg
    63721 tgtcgtgaca cgtccattca cttttgaagg accgaaacgt ggccgttttg ctgcagaagg
    63781 tatcgctcgt ttgaaagaaa atgtggatac attattaatt atctcaaata accgtttatt
    63841 agaagttgta gataaaaaga caccgatgct tgaagctttc cgtgaagcag ataatgtttt
    63901 acgacaaggt gtacaaggta tctctgattt gatcacagcg ccaggttacg ttaaccttga
    63961 ctttgctgac gtgaaaacag tgatggaaaa ccaaggtaca gcattgatgg ggatcggtgt
    64021 ggctagtgga gaagatcgcg tagtagaagc aacgaaaaaa gcaatctcct ctccattgct
    64081 tgaaacatct attgatggag ctgaacaagt acttcttaac atcacaggcg gtttggatat
    64141 gacattgttc gaagcacaag atgcttcaga tatcgtagca aatgcagcaa ctggcgatgt
    64201 aaatatcatt ctaggtacat ctatcaatga agaaatgggc gatgaaatcc gtgtgacggt
    64261 catcgcaaca ggtatcgatg aatcaaaaaa ggaacgcaag tctagccgac cagctagaca
    64321 agcacaaatg caatcacctg ctcaaaagac tgtattagat atggatcaag ctaaaccaac
    64381 ttcttcagaa gaagaaaaca gttttggcga ttgggatatc agacgtgaac aaaatgttcg
    64441 tcctagagtt gatgattcca attttgacaa tatcgaaaaa aaagaatttg atacattcaa
    64501 ccgcgaagaa acaaaatctc atggcgatga tgaattaaat acgccaccgt ttttccgtcg
    64561 taaaaaataa aggagaggaa gagcacatga ttgctgacaa cttgcagaaa atcaagcaag
    64621 aaattcagga ttcgtgtgct cttgttcatc gtgatccgaa agaagttaca ttagtagctg
    64681 taacaaaatc tgttgaatcc gctcaagctg aagaattggt tagagctggc gttatgaatt
    64741 gtgcagaaaa ccgagtagat aaattattag aaaagaaaca agatttattt gattttcctg
    64801 aaataaagtg gcatttaatt ggtaatttac agcgcagaaa ggtaaaattg attgtaaatg
    64861 aaattgatta ctttcatgcg ttggacagtt taagattagc agaagaaatc cagaagcggt
    64921 tagagaaaga attatcctgt tttattgaag taaatgtttc tggtgaggaa tcaaaacatg
    64981 gaatttcacc agatgagctt ttaccgtttg tggaatcttt agctgcctgc acaaaaatca
    65041 aggttgttgg gttgatgact atggcgccta aagaagcttc tgatgagcaa atccataaag
    65101 tgtttggtac gctgaaagaa ttgcgtgatc ttgttcaagc aaaaggttat gcccatgcac
    65161 catgtagtga attaagtatg gggatgagtc aagactttca aattgcgatt gaagaaggtg
    65221 caacatttat ccgtgtagga acagcgctat tcaaagacga ataaaggagg aacaaaaatg
    65281 ccgcttttaa acagaggagc aattgctaat tttttcggat tagctgatga ggaagagtac
    65341 gaataccaag attatcctga aacaacaaaa aaggctgtac agccaactaa aaaaaataca
    65401 acacagaatc aatcaactca ttctgtatct gctgcgaata ctcatgaaaa acaaaaaacg
    65461 gcgacttcac gtcctgtaac gcatgaaagt attcagccgg ctgaaaagaa aaaagtaatt
    65521 gaactacatc aatcacctac aaaaactgta gcgaaagaaa gaacagcttc aagaacctct
    65581 acacaaccta aagcaaatct tgctggaaaa atcactgtaa tggaaccaag agcttattct
    65641 gaagctatgg cgattgctaa acgaatcatt gctggagaag caaccttagt gaattttcat
    65701 ttagtagaag aaaaacaagc gagaagaatc gttgattttc taacaggaac agtttatgca
    65761 ctagatggag atatcaaacg tgttggagat gagatttttc tttgtacacc gactgggatg
    65821 gagattgaca gttcaaccgc tcaatctttt gcagatgcga atttgtttga tctgtaagag
    65881 gaggaactac gatttatact attgcactat tacttcattt acttcaacgg gcagcctatt
    65941 tctatagcat tatcttgatg gtatatgcat tgctctcttg gtttccaggc gggtatcaat
    66001 cagggctagg acgattatta gctaagatct gcgaaccgta tatcagtttg ttcgatcgtc
    66061 tgcctttgag gattggaccc ttggatttca caattttagg ggcaatcctg atcttgaact
    66121 tagccgtaca aggtttagca cagatcgtta tatggataac tgtccattta gtttattgat
    66181 tgaagcaaca aaatctttat tctcagaata gataggaggg gaaaattttg gatgcaaatg
    66241 tataccagca ctttcgggca gatgaacgta catttatcga ttcggtaggc gattggattg
    66301 aacaggttca aggacaatat gcaccctatc tgaccgaatt tcttgaccca agacaatcct
    66361 atattttaga aacactgatt cgacaaagca gtgatttgcg tttcatgttt tatggcggat
    66421 atgaacaggc agaaagaaaa agatgtttga ttttccccga ttattacgaa cctgtagagg
    66481 aagattttga aacagcattg tatgaaatcc attatcctag caaatttgcc agcctaagtc
    66541 atgggaaaat ccttggaact ttagtgggaa cggggatcaa acgctcttac tttggcgata
    66601 tcatctcgga cggtgatcgc tggcaagtat ttattgcaaa tgaggtggat cattttgttg
    66661 ctgcacaagt aacaaagatt ggaaaggttg ctgtacgctt ggaaccaatc aaatacacag
    66721 aaatgattat gccgaaagat agctggacac aagaaagagg aacagttagt tccatgcgac
    66781 tagacagtgt gatctctgag atttataata tttccagaca gcggtccaag cagctgatcg
    66841 aagctggtaa agtaaaagtg aactggacag aaaatacaag acctgatttt gtacttgaac
    66901 tattagatat tatttcagtc agaggttatg gcagagtcca gatccaagaa cttgagggga
    66961 agacgaaaaa agaaaagtac agggtactgt tcggtgtatt acgtaaataa aataaaaagg
    67021 tggtttactc atggctttaa ctccattaga tatccaaaat aagacattcc cgacaaaaat
    67081 gcggggatat aatcaagacg aagtagatga tttcttagat ttagttgttc gtgactatga
    67141 ggaattgact caaagaaatc gagaattaga aaaagcagtc aaacattctg aagaaaaact
    67201 tgagtacttc aatgaattaa aagatgcttt gaaccaatca atcatcgtag ctcaagatac
    67261 ggctgataaa gtaaaaacaa gtgcaagcaa ggaatccgaa gtgatcgtta cttctgcaca
    67321 aaacaaagca gatgagttag ttgcgaacgc tgaaaaacgt gcacatcaat taacaactga
    67381 tgcagaagaa aaagcaagaa aaatcttgac agatgcaaca gaaaaagcaa gacagcttgc
    67441 gacagaaact gaagatctta agaaaaaaac acgagtattc catcaacgta tcagcttgat
    67501 gcttgagtct caattagaac aagtgaaaag tccggaatgg gatgaaattt tacaaccatt
    67561 ctccagctac gtgactgaca gccatgaagt gatcaaagaa gttttagcaa aacagcttga
    67621 caatgaaaat gatactgatg taaactcaga cacaggagtc atagaagcac ctatgacggc
    67681 atttgataca caggctattg atatctcgat cgtgcctggt gaaaatgaaa acgagtagaa
    67741 cagaaaagca ctttgttatt cttaaagcga gccgatgaga gtggaagttc ggtaagacac
    67801 tgcatggtga aagatcctct acttgagacc tgcttttccg aaattagagt aagaagcagc
    67861 ggctgacctc gttattggtc acagagagtt tgcactagat agatgcaact aaatttgggt
    67921 ggtaccacgg catgttcgtc ccttgcggct gaacatgctt ttttgtgtcc ggaaaacaaa
    67981 taaaggagtg tatggttgaa tgaaaatgaa agaaaccttg caattaggaa aaacaaaatt
    68041 ccctatgcgt ggtaatttgc caaaccgaga aggcgagtgg caaaaagaat gggaagaaaa
    68101 tcgaatctac caaaaaagac aagagttgaa cgaaggaaaa cctagctttg ttcttcatga
    68161 tggacctcca tatgccaatg gtaatatcca tttaggacat tcattgaata aaatcagtaa
    68221 agacattatc attcgttcaa aatcaatgtc tggctatcgt gcaccatatg ttccaggatg
    68281 ggatacacat ggattgccga ttgaacaagt attggctaat aaaggcgtga aacgtaaaga
    68341 aatgtccatg gcagaatact tggaaaaatg tcgtgaatat gcactttccc aagtagataa
    68401 gcaacgagca gatttcaaac gcctaggagt tgcaggagat tgggaacatc cttatgttac
    68461 attagatcct tcttatgaag ctgcacaagt acgcgtattt ggtaaaatgg ctgaaaaagg
    68521 ctatatttac aaaggattga aaccaattta ctggtctccg tcaagtgagt cttctttagc
    68581 ggaagctgaa attgaatata aagatgtaaa atctccatct atttttgtag ctttcaatgt
    68641 caaagacggc aaagatattc ttgatgaaga tacagctttt gtcatttgga cgacaacacc
    68701 atggacattg ccagcaaacc aaggtattgc tgtaaatcca aaatttacgt atgtattggt
    68761 ggaagccgat ggccgtaagt ttgtcgtagc gaaagatttg ctagaaacag tccaatcaga
    68821 aatcggttgg gaaaatgtaa cagttctaaa agaatttgct ggacaagaaa tggaatatat
    68881 gactgcaagt catccattct atgaacgtga atcacttgtg attttaggcg atcatgttac
    68941 tttagacgct ggtactggat tagtccatac tgctccagga catggggaag atgactatat
    69001 cgctggtagc aaatataaac tatctgtagt gtcacctgta gactcaaaag gattgtttac
    69061 agaagaagca cctggatttg aaggtatctt ttatgacaaa gcaaatccta tgatcactga
    69121 tctattaaaa gaaaaaggag ctttgctgaa gctagatttc tttactcata gttatcctca
    69181 cgattggcgg acgaaaaagc ctgtgatcta tcgggcaact ccacaatggt ttgcatctat
    69241 cgataaattc cgtcagaata ttttggatga agtagaaaaa gtagagtggg ttatcccatg
    69301 gggtaaaaca cgtttgtata atatgatccg tgaccgcggc gattgggtaa tttcccgtca
    69361 gcgtgcatgg ggagtaccac ttccgatttt ctatgctgaa aatggagaag caatcatcac
    69421 accagaaaca atcgaacatg tggcaaaatt atttgctgaa catggatcaa ttatctggtt
    69481 tgaaaaagaa gcgaaagaac ttcttcctga aggatttacc cacccaggtt ctcctaatgg
    69541 cgaatttaca aaagaaaaag atatcatgga tgtctggttt gattctggtt cttctcatga
    69601 agctgtttta cgtcagcgac cagaattatc attcccagca gatatgtatt tagaaggatc
    69661 agaccaatat cgtggctggt tcaactcaag tatcacgact agtgtggcta tcaatggtgt
    69721 agcaccatac aaatcagtta tttctcaagg atttgcttta gatggtgaag gccgtaagat
    69781 gagtaaatct ttaggaaaca tcattgcacc agaaaaagtg atcaaacaat ttggtgcaga
    69841 tatccttcgc ttatgggtat ctagtgtaga ttatgaagca gatgttcgtg tttctatgga
    69901 tatcttaagt caagtggcag aagtatatcg taaaatcaga aatacgatgc gtttcttatt
    69961 agcgaataca gaagatttcg atcctaaaaa agatactgtt tcgtacaatg atttacgttc
    70021 tgtagacaaa tatatgaccg ttcgattgaa ccaagtaatc aaagaaatcc gagaagaagg
    70081 gtacgacaaa tataacttca tgcatattta ccgtacagtt atgaacttct tgacggttga
    70141 tctatcgtca ttctacctgg attttgctaa agatgtagtt tatattgaag cagaagatga
    70201 ttatcaacgt cgttgcatgc aaactgtttt ctatcaaaca gctgtagctt tgacaaaatt
    70261 attgactcct atcattccgc atacagcaga agaaatctgg tcattcctga aagaagaaga
    70321 ggagtacgtt cagttaagcg agtttcctgg ttatgaagag tttgcaaacc aagaagaatt
    70381 gatggatacc tggactgctt tcatggactt ccgtgataat gtcttaaaag cattggaaga
    70441 agcaagaaac agcaaattga ttggtaaatc tttggaagca aaactaactg tttatccaaa
    70501 acaacaagtt cgtgaaatgt taaaagcttt ggatgcagat attgcacaat tattgatcgt
    70561 ttcaccagac tactttgaag ttatggcagc agatgaacaa gtgccagata acgctatggt
    70621 atttgatgat gttgctatta cagtggaaaa agcagacggg gaaacttgcg atcgctgtcg
    70681 ccaagttcgt aaagatgtag gagtagatga aaaacttcct catctatgcg gtcgttgtgc
    70741 aaaaatcgtt gaagacttct atcctgaagc tgtagctgaa ggattcgaag aaaagtaaaa
    70801 gggaaaaggg ggtgtgacat gttctttgtc acaccccctt ttgttatcaa tcgtttaatt
    70861 ttccacgttc acgataccag ttatctggtt gccagatcca ttcgaatccg tctttttcaa
    70921 gtagttcgaa agctgcttta ggtcccattg atccagcttt gtagttggga aaatccggtt
    70981 gtgtttggtc ccaagctttt cgaatgacat ccacgatatg ccaagattga gcgacttctt
    71041 cccaatgaga gaagttcgtt ccatcaccat tcaacgcatc taatagtaat ttttcgtaag
    71101 cttctgggct attttcaacc atttctgcac tatttctaaa ttccaatttg attggttccg
    71161 tttcaaatcc ttgccctact tctttcccat tcaaggataa agaaaatcct tcagttggct
    71221 gaatatagat cgttagaaca ttaggtggaa gtgtcgtatc gtcacatggt tcatcgacag
    71281 atgttttgaa tacattaaca ggaacttgtt tgaatacgat gttgatccga gtcccttttt
    71341 cagtcaaacg tttgcctgta cgtacataga aaggaacacc tgaccaacgg aagttatcga
    71401 tagtgaattt gcctgcgacg aatgtttcag tctctgattg agcatccact ttgtcttctt
    71461 cgcgatagcc cttgaattgt acaccatcca attcaccttg agcatattgc ccgcgaacga
    71521 agttttctaa cacttcttct tcgttataaa tgcggatagc tttcaatgct ttgatctttt
    71581 ctgtacggat ttctttttcg gaaaatgcta ctggcggttc cattgcaagt aatgctacaa
    71641 cctgtaaaat atgattttgc accatgtctt taagtgcgcc actatgatcg tagtagcccc
    71701 cgcgatcttc tacaccgagg ttttcgccaa aagtaatttg gatattgtcg atatagcgat
    71761 tgttccattg agcctcaaaa atattattgg caaaacggat agctgagatg ttttggatca
    71821 tttcttttcc taaataatga tcaatcctga aaatatcttg ttctgggaat acttctctga
    71881 tttgctggtt caattcaaaa gcagactggt aatcagaacc gaacggtttt tctatgatca
    71941 aacgattgaa gccatttttt gtcataatat tttgtgattt caaatgagaa acgatcgttc
    72001 caaaaaattg aggtgccata gccaaataat agacacggtt accgtttaat tgatagtgtc
    72061 catctaatcg gtcagacaat tcttttaatg tctgataatg cgttgaatca tttacatcat
    72121 gggattgata gtaaaaatgg cttgcaaagg tagttgcttc ttcatctgaa ggattcaatg
    72181 cacggattgt ttctttgaca acttcacggt agtgctcatc gctccaggga cggcgagcgg
    72241 ttccgattac agcaaaatgc tcgcctaaat ttccttttct gtaaaggcgg aacaaagacg
    72301 ggtacaattt acgctgggct aggtcacctg taccgccgaa tatcgtaaac aatacatttt
    72361 tttcattaga catgtggata cactccttta tattttatcg acaaaaatcg tgctggccgc
    72421 cttaaagctg acggggattt tctttctatc attttggata gtgatcggtc cttcataagc
    72481 tgcgatgtca acgatctcat attcttcgtt gatattcagg tcaatagtga ctaagtaatc
    72541 caacaattct ttttcatcaa gcactcgtgc gatacgcact tttgtaccga caggatagga
    72601 ctccaatgtt tgtcggcgtt cttcatggac aacttcctct tttttaggaa tcgatcctcc
    72661 atgaggacaa tgttcaggat gattcaaata gttttctaaa tgatctgcaa gatgttccga
    72721 agtcacatgt tccaatactt cagcatcatc atggacttca ttccagctat agtctaaatg
    72781 ttcaactaaa aaaacttccc ataagcgatg tttgcgaatc agactgctag ctttttgcag
    72841 tccgcttgca gtcaattgta caccttgata aggggaatgt tctacaagct cttctttcac
    72901 aagtttagaa atcatttcac tgacagatgc agctgagaca tctagactag atacgatttg
    72961 tttattgttg actttcgttg tatctccacc tagttctaaa atgattttca aataatcttc
    73021 tcgatttggt gtcatattcg atcatccttt catggtaaaa aaccatcatt agtaagtgta
    73081 acaaaaaaaa cgttaattga ctatttttct aaataaaaaa caaaggattt ttagacgttt
    73141 ttacaacaaa aaacgaaaga tgatagagaa gactcattct ttcgtttata aaggatatat
    73201 atatacattg ggagggatct atttttcaga taacaactta tatgaagtgt ctgcagattc
    73261 gtcataaaga gtttgttcgg gataagaaaa gataagataa aaaccatact gatcacgtac
    73321 gactaaacga tattcatcta tttctaccac agatgtgcca agagactgac cgttgatcaa
    73381 aaacgtgtaa tcagatgtaa tctgtaattg ttgtttttgc tggctatcac taaagaacca
    73441 tgtaccttga tactttgaga gtccttctga cttttccgct tgttttttct ttttcaagta
    73501 aataaaactt gagagaacgg taatgagtga accaagaaaa tagatcattt tttttatcac
    73561 caaatcactc ctttatgaga aaataatcgc atagacatat tctttcttct ttatttcatt
    73621 gtaccgaata aaagctaaaa tttctctaag actttcgact ggttttttta ctgtttttct
    73681 acaaattatg ataggataca tagtaggaag aaaggtgaca taatttgaag tatcagcaag
    73741 tggaaatagc tttttttatt gaccgcccga atcggtttat agcacattgt atgaaaaaag
    73801 acggagaaat aattattgcg catgtcaaaa atacaggtag aggaaaagag gtcctgatac
    73861 caggcgctga agtggctatt gtatttgctc ctggacctaa acggaaaacc gcctatgatc
    73921 tgattgctgt aaaaaagaag ggtgactggt ttaatatcga tagtcaattg cctaatcggc
    73981 tggcaattga tggtatttta gacggcacga tccttttacc aggattaact ggtccattta
    74041 cggtatacaa gcgtgaagta acttatcttc actccaaatt tgatatttat ttagagacgg
    74101 tggtcggaca aaaagcattt gttgaagtca aaggtatgac acttgaaaat aaagcgattg
    74161 gtgcttttcc tgatgcgccc acactcagag gattgaaaca tataggagaa ttaacgtatg
    74221 ccgcacaaga tggttatgcc gcttatgtct tgtttattgc tcagttcgaa catcttcatc
    74281 tggcaacgat ccatgaagaa atgcaaccag cactagctga tatggttcga catgcgcagc
    74341 aaagcggagt tcaaatcctc gcctataatt gtcaagtatc ggcagatgag gtaactgtca
    74401 agcaggccat tccatttgat gtagatatcc cttttgaaga tcctatacaa tagaaagaag
    74461 gtaaaataat gatcaactta ggtattatcg gaacaaattg gattactcat caatttgtcc
    74521 aagcagcttt aagcacaaaa aaatatgaat tgacagcggt atattctaga catttggaaa
    74581 aagcacagga atttggttct cattatgaag gggatatcga attcgcaaca gatttgaaga
    74641 cttttttcaa tattactcat atggacacca tttatattgc ttctccgaat agtcttcact
    74701 ttagtcaagc taagcaagca attttggcag gaaaaaatgt gatagttgaa aagccagctt
    74761 tttcgacgcc aaaagaaatg gatgaaatca tccatttggc aaatgaacac aatgtgtatt
    74821 tttttgaagc agcaagaaat atccatgaat caggttttaa aaagattgcc gattacttac
    74881 cattaaaaga cgagataatc ggtgcaaatt tcagctatat gaaatattct tcgcgctatg
    74941 accaagtatt agatggagaa gaaccgaata tcttctcgac tcatttctca ggtggtgcat
    75001 tgatggattt aggtgtttac cttgtatatg cagctgttgc ttggtttgga atgccaaaag
    75061 aagtccatta tttcccaaga aagatttcta ctggtgtaga tggtcttgga tgggggatct
    75121 tacgttatga gaattttgat gtatcgatcc agccaggtaa aatcggtgat tcttatttac
    75181 cgtcagagat ttattttgac tcaggaacgc tagtgatgaa tggagtcaat gcaattgaac
    75241 aagcacaatt tcatgatcgc gcgcataaag aaatcattga tttggcggta acagctgcag
    75301 aaaatccaat ggcagatgaa gcagaggatt ttgccaatgt catggctcat ccgaaagatc
    75361 cagcttgggg attgttgtat gaagagtgga tcgagctagc tagaaatgtg aaccaagtga
    75421 tttatgattt aagaaaaaat ggcggcatca aattcgatgc agataatgag gaagattttt
    75481 aatgaacgaa tttgtacaag tatttcccga aaattggcag aaaaaatatg aggataaagg
    75541 gtttatctca ccttctctta ttcaacgagc agtttttcag ccactaagta ataaacaaag
    75601 tatagtagcg gtttctccta caggttcagg taaaacactg gcttatcttt ggcctctact
    75661 actaaacgtg gaaccaggtg aagcaagtgc gttggtcatt tttgcttctt ctcaagaact
    75721 agctattcaa gtagcagatg ttgcacgtga atggggaaaa gacaaagagt tgaaagtcca
    75781 atctttggtg ggcggagcca acgtcaaacg tcagattgag ggtttgaagg aaaaaccaga
    75841 aatcttgatt ggtacaccag gaagaatatt ggaattgatg aaagcaaaaa aaataaaagc
    75901 acatcaagtg aaaacaatgg tatttgatga agcagaccag ctatttgacg ctgggaacag
    75961 ccaaatcatt gatcaaattc ttcatcaagc tccaacagag tatcagctag cttttttttc
    76021 agcgacagca gatcgttccc ttgaaagcat tgaaaaaatc actgggaaaa cgtttgagac
    76081 aattgacgtg acagcagagg acgattctcg aaaaggactg agacattact ttttacgtgt
    76141 accgatacga aagaaagatg actacttgag acgtctcacg catatagaag attttcatgg
    76201 tctgattttc tttaatcaac tgactgaatt aggcgtaatg gaagaaaaat tgctgtatag
    76261 aggtgtaccg gtaggaagtc tggcctctga tcagaacaag ctactccgaa aagcagcgct
    76321 agaacaattc aaaaagaaaa tggtcagagc acttttgacc acagatgtgg cggctagagg
    76381 tttagatatt acaggtcttc cttatgtagt gaatgcagaa gttccgttaa gtgaagaagc
    76441 ttatttgcat cgttcgggaa gaactggtcg aatgggtaat gaaggaatag taattacact
    76501 cgtacaagat aataatctaa gagatttaaa acggctttta cgtccatcaa atataacact
    76561 tgaagagatt tttttatacg gaggtaagct gcaaactgag cagccaacca aagaagatgc
    76621 agctcctgca gtaaataaaa agtatgcgaa aactttttct ggaaaggagc agaacccaga
    76681 atataacaaa gaaaaaataa gaaaaaaagt taaaaataaa tcaaaaaaag agagaaataa
    76741 aggagcaagg cgcaaataag cgccttttta tgctatgatt atgaaaacgg gaacaaaatt
    76801 ggttgccaga ggaggggtta tgtgaaagaa cgtcaagaag agatcttgca gctattgaca
    76861 gaaaaccaac aaggattgac agcaagtgat gtagctgagc gcttaactat cgatcgaagc
    76921 aatgcaagcc gatatttaag tgaactatac aaggcccatc atattgtaaa aaccgctggc
    76981 cgaccagtcg tttactcttt gccaacggaa aagtcaaaat ctgatgaagt gcatgtcgac
    77041 tcttctacgc aagtgacttt tgaaacactc gttggagaaa atgattcttt aaaagtcagc
    77101 atacagcagg caaaagctgc gattctttat ccaccgcggg ggttgcatac gattattttt
    77161 ggagaaactg gtacagggaa gtcgatgttt gctgaatgta tgtatcattt tgcaatcgat
    77221 tcagagatgc tttctgcaga tgcgccattt gtttctttca attgtgcgga ttatgctcaa
    77281 aatccgcaac tgctctttgg acacatcttt gggatcaaaa aaggggctta cacaggagca
    77341 gctcaagata gtcccggtct aatagccaaa gcagacggcg gtatattgtt tttagatgag
    77401 atccaccgtt taccgccgga agggcaggaa atgctgttta ctttcattga taaaggtatt
    77461 taccgtccgc ttggagaaag tgcacaagta catgaagcat ctgttcagat cattggggcg
    77521 acgactgaat cttcagaaag tttcttatct acgttcaatc gacggattcc tatggcaatc
    77581 accttgccga atcttgcttc acgttcactg gatgagcgtt atgaaatcat ctctcttttt
    77641 atcaaacaag aagcgaatcg tttgaatcaa cgtatcgata tcgaaaaaga agcgattctt
    77701 gccttcatgc tttatgatgc ggaaggaaat atcggtcaag tgaaacgaga cttgaaacta
    77761 gtctgtgcaa aatctttttt acattaccgt actcatcatg agaaaaagct aatcattcga
    77821 aaagaagaac tttcccttca agtacaaaaa ggattactga aaatcaagga aataccggaa
    77881 cgtctcgacc gattcatgga cagcaaaagt cagtatttga catttgaacc aggatttgct
    77941 gatgttgtct ggtcacaaga tccagaacga aacatgcagg tctataacga tattgaggaa
    78001 aaagtcactt ctctttccga aaccggtgtg gagaacattg atctagagac cctcatttca
    78061 aaagatgtgg atgcttattt ccagacatat gtcaaagaat tgactaaaag ttcgattccc
    78121 aaagatcttt tgccagatga aatctggcgg ttaaccaatc aattgtatga tgtggctgaa
    78181 aaacggttag accgtattta taatgaaaaa gctcgttttg cttttgcttt gcatctgcaa
    78241 agtacattgg atcgtgtgag agaaggtcat atgatcgtcc acccagattt gaataacgta
    78301 cggaaaaatt ttaagaggga attccaggta gcaatcgatc tttcaacgat cattgaagaa
    78361 gaagaacaag ttgagattcc ttttgatgaa atcggcttta ttagtatgtt tctttctatc
    78421 aatctaggag aaagtgagcc tgttaaagaa aacaaagtag atgttctcat attgatgcac
    78481 ggcagacaga ctgcttcaag catgttggag atggcacaag aactattagg aacaaaagta
    78541 gggaaagctt ttaatatgcc actggttatg gaagttcaaa caatgtatga agaagtgtta
    78601 caatatgtca aaaactatca agagcatttg acgaatggcc tactcttgtt aacagatatg
    78661 ggatcattaa acaccttcag tgatttgatt tatgaagaga ctggcattcg gacgaaagct
    78721 atcacgatga caagtaccat gattgtgata gaagcgatac ggatggcaag tgttggaaga
    78781 agcttagaag atatttatca aaatatccag ctttcctttg aatcgatcgt acgtgatcag
    78841 ttcaaagcgg aaaagtctga aactttacag cgtaaaaaag ccgtaatcgt gacatgcttt
    78901 actggtgaag gagtagctgc caaattatat cagcgtatta tgccagtgat taatcaaaat
    78961 aaggtagaac tgatccagat gcagttttta gaacgtgaat cattcaaaaa acacatcgat
    79021 gccttattgg aagaatatga gatcaaagca attgcgggaa cagttgatgt tgattatcaa
    79081 aatatcccat ttttttcagc ctatgacgtt tttgatgatg aaaaactaaa tattttaaag
    79141 cgtatagctg atgatgagat cccgacagct aaaattgtcg attcacttgc tggatcatta
    79201 agcgatgtct tttctattga tgaactgatc cgttcattgc aaaagacagt tcagcagatc
    79261 cagaccgatt tgtcgattat cgtggaacct ggagtagata ctggaatcgt tatccattta
    79321 gccttcatgt tagacggatt gatcaaacaa gaaagccatc ggcaatttga gaaactgtct
    79381 attttctcaa aaatttatcg tttggaaatg gatatcgttc gggcaaactt gatggcacta
    79441 gaacgaaaat atcaggtaaa aattccagaa gatgatatcg catttcttac acaaatgttt
    79501 cttgaaaata aaataaaaaa atgaacacac taatcatact gtttacacac taaacatctg
    79561 tgtgcgcact ataaaaaaga gctaaaaagc atgaaaacgc tatttcagct ctttttttta
    79621 ttggcatgct tcttgcgtta tataaaagtg taaaaaaata aaaggagtgt taaaaatggc
    79681 aaaaaaaaca atcatgttag tttgttcagc agggatgagt acgagtttat tggtcacaaa
    79741 aatgcaaaaa gcagcagaag aaaaagggat ggaagccgat atttttgcgg tctctgcctc
    79801 agatgcagat aataatttag aatctaagaa tgtcgatgta ttattattag gtcctcaagt
    79861 acgtttcatg aaagctcaat ttgaacaaaa acttgcgcct aaaggtattc cattagatgt
    79921 catcaatatg caagactatg gcatgatgaa cggagaaaaa gttcttgcac aagcagaaaa
    79981 tctaatgaaa taaatcaagt atgcagttgg gggtataaca acgtggaaga tcaacaaaat
    80041 ctagaagcca tcatggggtt aatcatgttt ggcggtaatg caaagagcga tgcaatggaa
    80101 gcgattgcgg ctgctaaaat cggtgatttt gagttagcgg ataggaaaat cgctgatgca
    80161 gaagaatcac ttatacaagc gcatcatgca caaacagaca tgttgacaca agaagcacaa
    80221 ggaaatcata tgcaagtgac attattgact gttcacagtc aagatcactt aatgacatct
    80281 attgcgttta ctgatttagc aaaagaaatc atcgaacttt atcgtcgcgt atacagcgaa
    80341 taaatacaac ttcttttttg aacggaagaa gaaaaatttt tgaacggatt ttttattttg
    80401 ttataaggag aactctcttt atataaaaaa cttataggag gaagtaaaaa atgaacggac
    80461 tatcaagttg gatggagaaa tacatcctgc cggttgccgc aaaaatcgga gcgcaaaaac
    80521 atttagttgc tttgcgtgat gcttttatcg gcatactgcc cgcaacaatg gcgggatcag
    80581 tcgctgtaat gatcaatgca attattcgtg atttaccgca acagtttaac agtacctatg
    80641 ctgacagttt agcagcagac aaaggaatct ttgccgtatt gaatgtcatc atcggaatca
    80701 atggttttgt ctggaacggt acactagcaa tcgccggatt gatctttgcc ttttcttggg
    80761 ggtataatct tgcccgagct tatggagtaa atgatctagc tggggggatc gttggtttag
    80821 ctaccttgat tcaaggtatt tcctttggtc cagcattatc agcagcatta gatgtgaatg
    80881 ttccttcaaa tgtcgcagat gcaatcaata gttctgagat tggtgcaacg attgcagatg
    80941 gcacactgtc agttggatta tggggttggc taaaactaga tcatttgaat ggaaacgctt
    81001 attttacagt tatgatcatg ggagctattt cagtcattat tttttgtaaa ttgatgcttg
    81061 ccaacattac gatcaaaatg cctgattcag taccaccagc agtatctaaa gcatttgcag
    81121 ccattttacc agcgacgatc gctttatacg tcattgctat tatcaattat atcgtaggtc
    81181 gtgtagctga tgggcaactg atcattgatt tggtgcaaaa atatattgca gaaccattcc
    81241 taggattatc tcaagggttg ggagcagtat tgatcgtcac agtatttgtt caagtattct
    81301 ggttctttgg tattcatgga tcaaatgtat tggcaccagt gctagaggga atctggggac
    81361 aagcacaact aatcaatatt gatattttcc aaaaaggtta taacggaaaa actggtacac
    81421 cagccgtgtt agatgcaatc gaagatggaa aagcttatat gtgggtccgc ggatcgttcg
    81481 atgcttttgc atggtttggc ggatcaggcg gaacgatcgt cttactgata gctatcttga
    81541 ttttctctaa acgtgcagat tatctaacag tagctaaatt atccattggg cctggtatct
    81601 tcaatatcaa cgaaccagtg atgtttggtc tgccaatcgt attgaatgca atcatgttta
    81661 tcccattctt gattgctcca gtagtagcaa cagcaattgg atggacagct acttatcttg
    81721 gcctagtcgc tccggtatcg cagcaagtca catgggtagt accgccgttc ttattgtcat
    81781 tcttagcaac aggagcggat tggcgggcac cgatcgtaac attagtatgt atggtcgtga
    81841 ctttcttgat ttgggcacca tttgtcatct ctgcaaacaa aatggaccct gccgcaggcg
    81901 aacaacaata agatgaacgt gaggagcggg acgctttaag tttcgttcct cataatgaat
    81961 tttcgaggag gaactgaaat gattacaatt gccagtgcaa tgcaacaaga tgaaatcaaa
    82021 gaattgttag aaggatacaa tgaagaagga atgactttta catttaaaga aaaacaagga
    82081 atcaagctgt tctttgaaac aagtgcagaa gatccggaag ttgcggctaa aaaagcaaag
    82141 gaactaatca aagcacagcc ttggggaaca gtcctttatt ttcaatcaac agctgtttag
    82201 aaaatggttt aaaaagatag gatggttgag atgataaaaa acggtttatt tttatgtagt
    82261 attggttctt tgatcgtgtt gtatagtttg aatccacatt cgcaaaggta tgatttgtat
    82321 agtatggtca caggtctttt tctaacagga ttaggaatct atttcttcat gaaggggaaa
    82381 aaaagagaag aagcaaagga gaaaaataac taatggaaat cacgaaaaaa ttaaatattc
    82441 cagcatcgtt tttttacgat aaagttatgg actctgtcct tttcgatgta cgtaaagcga
    82501 ccggcaaatc agtaactaga aaacagctga aaaatttgga gtacgtcaaa caattctcgc
    82561 aaaataaccg ggctcgcata aaaatcgaag aagtcattga aaaccagtct tataagtttc
    82621 gtacatcgac aacgaagaat gaattcgtcg ttcattatca aatcaaacca ttggacgatt
    82681 cgacctgtga ggttcattac acagaaaaaa tggagtctta tggcatgctt caaaagttga
    82741 atgatatgct tttaggaaca atcttgatgt attttaaacg gagacgtttc aaaaaaatgc
    82801 tagatatgat cgaagcaacg tattaaatca atgaaacatg gtactattta gttattgaaa
    82861 aatgaagtaa gctagaagga atttttcata ggaagataga tctttcctgc gaatcctcac
    82921 tagctttttt gtaggaaggg gcagcaaaat gacaaacaaa gtaagagagc taggtgtatc
    82981 ttcgattgag gaaatgtttg atttagccac ttatgcattt aatggggcag atacacctga
    83041 aaggcgagaa cgttttcgta cacttgcgga gaattcttgg aattacggat tttttgatga
    83101 ggaggatcgg ctaacaagtc aagtcatggc gacccctttt ccagtgaatt tttacggaca
    83161 agagtaccta atggccggca ttggctatgt tgcttcttat ccagaagcaa ggggacaagg
    83221 cgggatcaat cagatcatgg aaaagatcct tgaagattgc cgtgatcgta aagtaagctt
    83281 atcttatctg gcgccattct cctatccctt ctatcggcgc tatggctatg aacaatcatt
    83341 tgataaaatc agttatcaac taaacagtcg tgatgtgccg tttatcaaaa aaaaatctgg
    83401 aaaaataaag cgtatggatt ttgaagatgc aaaagctgca atcagaagaa tttatgaaca
    83461 gatgccggaa aaccaacgag ctggtctgaa gcgcgaagac tggtggtata cgtataaatt
    83521 caagcaaaaa ggcaattacc agtttgcttt gcattttgat gataatgagg aagcaacggg
    83581 atatatcgtt tatcagcttg caacgtcttc ctttattatt gcggagtggg gatttttgga
    83641 tcatgatgct ttttgcagcc ttgttcgctt cgtaagttct cacaatggtg cttttgaaac
    83701 atttgaatat tcatgcggct acggcggtaa tgatcaaaat tatctattag aaaatccatt
    83761 tgcttctgta atgatcacac cttatatgat ggcgaggatc gtagatattt ctttgttttt
    83821 ggaaaattat ccatttaaaa agagacaagc tgcatttgcc ctacaaatag aagaagatca
    83881 ttatgcgaaa tggaatgaag gaatcgtgga agtaacaatc gaaaatggaa aaaatcatct
    83941 ctcaaaagta gaacaaacaa aactcccaat cgttcgagga agtatccaac atatcacgca
    84001 gctattatta gggtatcgta aagtggaaga gttggtattc caagaaagaa tacaggtgac
    84061 aaaagaatat gaagaaacgt taagctcaat cttgccacag caacagccaa ttcttaatga
    84121 ctatttttga taaaaaacgg gtgatgacaa tatttttgtc accacccttt tgtttttcat
    84181 ttggcatttg aaggaaaatg ttaaagtaaa tcctcttttt tcgtaaattt gaattttttg
    84241 ttttcttttg ttttagggtt ttcttttttg tggtcttgga ttgcttcttt cgtaatcttt
    84301 tcccgatttt ttttagatga atctaagcgt tctgcgtata ctttttcttt tggcttatca
    84361 ttcattggaa aggacctccc tacattattt cattctacct ctagtttatc atctgttaag
    84421 gactagtgga aacgttttgc ctaacttata agctgatttt tttagcagat aagcttgcaa
    84481 gtaaaaaaca aacaagctac aattgattta ttgaaattgt tcctgtagct cagtaggata
    84541 gagcaatcgc ctcctaagcg ataggtcgct ggttcaattc cagtcaggaa cgtataaata
    84601 acccctgtat cctttgcggt acaggggttt gttttgtatt tgtgccaaaa atgtgccaaa
    84661 ctagttatca tttttatata aactatcgaa cacagtattg attttttctt tatcctgatc
    84721 ttcaagctct cgaacaatat gaagataagt agacattgta gtttctaaac tgctatgtcc
    84781 taaacgtttc gatacgctaa gtatatttac tccttgataa agtaaaatag atgcatgtgt
    84841 atgccttagt ccatgcaaag taaattgctt ttcaatccct aattctttta attttttgcg
    84901 caaatatttg ctgacggcgt ttgatgaaac taatccattt tttaagttga aaaaaacaaa
    84961 attatgaggg tttttgattt caaaattctc gaataattct ttttgattga ttttaaactt
    85021 ttttaagaga tcaatcgtat gtttatcaat ggaaattttc ctatttgaag tttcgttttt
    85081 tgtttttccc cattcattta atttataatt ccatgtttta ttaatagtga tgatttgatc
    85141 ttcgaaatcg atatcttccc atgttaatcc tagaagttca gcaaatcgca ttccagtggc
    85201 accagcaact aacacgagca taggagaaga gtactgcgca gaaaggtttt cttctacgag
    85261 tttcattaaa gatttaaatt gatcataatc taaatattta tcttcttttg gcttcaatga
    85321 atcttttcct ttgattactg cttttctagt tggatcaaac ggaattaatc cttcttctac
    85381 ggcatctttc aacgacgctc taatatggtt attaaactta ataacggtag attttacatg
    85441 gtctttagca tacttattta aaaagcgttg atatcccact ctatctaaat cagaaatcaa
    85501 taccgctggc atatatttct ttatgttcat taacgtatct tcgtattttc tataagtgat
    85561 aggagatact gttccttctt tataaagttg catccaatcc tcaaagtaat ctgataataa
    85621 tagatttttg cgatcccctt taaggccttt gttcaagtta tattctaatt cgttggcggc
    85681 atcttttgct tctccttttg tcttaaatcc tgattttctt atcttcgtgt attttccgtc
    85741 atcttttttg tatgaaattt cgtattgcca actatttcca cgtttgacta atcttgccat
    85801 aattgaatca gctctctttc tctgatacaa taggaactat aaagaagccc attgtttggg
    85861 ttttattatt ttttgcacat cctttttgct tgccggcgca aggatgtgct atttgtcgtt
    85921 ttaatggtat aattggatgt gtattagatc atccaatcag aggtgtttat tatgattaaa
    85981 gtgattttta aaagaataac tgaacttcca gagtttagat tatttgttga ttattggtat
    86041 gtctggtttt ttattgttgc attgctgata ggtctagatg tcatattaga aagaaaactt
    86101 aagtaagagt tgagttaata aattgaattc ctaaatgaga tattttgtag cccatatttt
    86161 gtttgccgac atcacctaat actatggagc taatcgtttt ttctaacaga ccaaaatcag
    86221 ataatctatt taagctacca tctattagct cttgtgaata gccagacatg ctgatatttc
    86281 cagtgaaatt ttcgtttcca cgactcatta agcatgctaa caattgaatc tcaatcgatg
    86341 ttaattgatt cagtacaaga agataatact cctcgttatc ccatgaagcg ttgttaattc
    86401 gaagtaaaca attcttataa agatttttat acatatctat tttattttgt gcctttgatt
    86461 tttctacctc gtcatttatc ccttcgaata ttccaatgag ttggtccttg ttctctaagt
    86521 tgaaaacatc ttctggaatt tgatcgcgaa tgttttctaa tgattcgttt aaatttttgt
    86581 agaatttctc gatgcgtttg aaacgcttct cgtttttaga cccaaaataa agtgactgca
    86641 caacgccacc aatataagga attgctccaa taccgccttc aactattaat tcaagatatt
    86701 cttttttggt tagtttttca ttgctattat ccatagttac ctcctatttt gtcatttcct
    86761 ttacaagcat tgtgactcct gatggcactc ttttgtatag gttttattat tgtgcacaat
    86821 ctaactctta gtggggcgtg gttcatttat tttttactta ctttactatt aatcatatcc
    86881 cattgagcat aggatttttc tatgttcgat cctcttgaac taatttctcc tgtaaaagtt
    86941 actttatcgc cctttgtaaa ggtatcagca ttgtttaagt ccttcgcaaa aattacatat
    87001 gaaactttag gtgttgcaga aatatcattc caacttttat catcgtactc tttgtctgct
    87061 ataatggcta ttctagtagt cattgattcg ataacagttc cttcaaaagt atatgtttta
    87121 ccactaatat atttagtaaa agctgtattt tgctcagtag ctggagtaat agaataataa
    87181 ctatctaaga aagcacccca gtcatgatta tttgtctcta aaaattcttc aaattgagtt
    87241 aggcttttat tgctgctgtt agatgtagta gtttgagtat cagatgatga gctttcctgt
    87301 ttgttattgt catttgcctc gtttgatgag gaaagcgaga aacctacggt agtaaaaata
    87361 atcccgataa taaggagaat cataggtgtt ttcttatttg tttttttgat aaatcttaca
    87421 attaacatga ttaaacctat aataaataaa acaataccag taaaaccaaa tataccgtcc
    87481 attaatagat cctctttctc ttttgatatt gaatattata aaccaagcaa ttcttttttc
    87541 ttaaaatcga attcttcttg attaataatc ccttcatcta acaactcttt atacttttta
    87601 atttcatctg cacttgaaat ttgtgtttct ttggaattat tatctaatat agattgttgc
    87661 ttctctatat atttttttaa attttccatt tcattccaat atttttttgt aaacataacg
    87721 gtgttttcat ctttcgtggc cgctaatata cctccgcgac tttcgtttcc gcctagcaag
    87781 gtaaattgta tataaccatt actcatacct ggttttttta attgtacggc tgatatattt
    87841 ttaaagggga tagttttttc tcctttaata ccttgattaa ctaaatttat aaatcctttt
    87901 ctaataattg aaatagaatc atcagttact ttaatcaagg tttttcctgg agattttatt
    87961 aaaatctctt tttccatttt ttcttcctca tttctgtgat atgatttttt ttgtagaagc
    88021 tcatatatga ggaaagagcc cgtgttgcag cacgggcttt tttaatgttt tgctgaaatc
    88081 ggttttttta ataattcttg atgtattcat acatattgcc ttgcgtaaga atattttttc
    88141 ttaaaatagc attggcagac agcataacaa gtgtatctga gcttattctg aatagaataa
    88201 tactccataa atttttcgag attaaactga gattcatcag tcagttcgtt ctcaatatag
    88261 atatttaata aaattagaat agctatttta tctgcttctg tttcaaattt tgagtgaaaa
    88321 gttgtagaag tatcgtacaa aactgaaaat tcaaaatgag aggcgctgaa atgtgcaagt
    88381 tcatgagata aatgaaaggc ttctgcagtt tcaccgtata gattttcatt caaaaaaatg
    88441 attctgggtt ttggatagta gaaaccaggc tctttcatct ccatataaac tactttcaaa
    88501 ttgtattcgc tcaacatttc tttcaatttc aaatacatac aaaccatcac tccaactatt
    88561 cattttcctc taaagcttta gcaattgcaa tcgctttacg cattgtctcc ttagatattt
    88621 cttttccatc aaaagaaaaa acagtatcgt cttctgataa atccacatgt ttaggggttt
    88681 ctctttcttc tctacctaga aggtagtcta cagagacatc gaaatagtca gcaatccgac
    88741 ttaattcatc tgaattagga gtattatttt tccactttgc tagataaccg ttagaatatc
    88801 caaaattaat ttctaactgc cgtatagata tctttttcct cttcgccaag tcttttatta
    88861 tttcataggt attcatcgat aaaacaacct ttctaaatgt ttacaaaaaa agtttagaaa
    88921 aatacgcaga aataatttga ctaattctga gtaatgagct atactatatc ttgtaaacag
    88981 atttaacaac taaaaagaca acaaaaaaca ctattgatat gtaaatgcag accgccaaga
    89041 aagctttaaa atcaatgttt ttatgtctta tttaattatg ctcttagtat agagtattac
    89101 tcagatactg tcaattgaat ttagaaaaaa gttgttaaat ttgtttacga atataaaaga
    89161 aaggaatgag aaatatgaac acaccgcaaa tttttaattt cgaacaaaac gaagttcgga
    89221 caattttagt aaatgatgaa ccatattttg taggcaaaga cgttgcgagt gttttgggtt
    89281 attcaaacac taaagatgct ttgtcgcggc atgtagattt ggaagataag atggggtcgc
    89341 gaatcacgac ctcaggtcaa tcaagagaga tgacaatcat caacgaatct ggtttgtaca
    89401 gtttaatctt aaaatcaaaa cttccctctg ccaaaaaatt taaacgttgg gtaacaagtg
    89461 aagtgttgcc agcaattaga aaacatggag gttatctaac tccagaaaaa gtagaagaag
    89521 ctttgcttaa tccagataca atcattcaat tagcaactca actaaaagaa gaaagaactg
    89581 gaagattaat cgcagaacaa aagattgcag agtacgaacc taaaatctcc tatttagata
    89641 gcatattatc ttctacagat tcagtaacaa ttagtcagat tgcagcagat tatgggatgt
    89701 ctccacaaca gatgaataaa ttacttcata aactaggtat tcagaaaaaa gtcggtaacc
    89761 aatggttatt gtgcaaaaaa cacatgaacc aaggatacac aaaatctcat acaactgaga
    89821 tcccgaaagc cgatggtggc actaaaattg taatgaatac caaatggaca cagaaagggc
    89881 gtctatttat ctacgaatta ctaaaaaaag aaggatatta ccctcaaatg gatttagagg
    89941 aaattggtta gaaaggagtt ttagtatgac tgacattgca gaaatcactc aacgagatag
    90001 agaaaaaatc aaagaatatg tcgaaagttc aaagttctta acttacacca tgcttgctga
    90061 aagatttgga attagcaaaa gctacttatc tttaatttta aacggtaaaa agacttctgc
    90121 agaagcaaac agaattatag attcgattat cactatgtac gaattgtaaa gggaggaaca
    90181 gctaatgcaa tatctagaag caaaaatccc aattccagaa ggctatgtaa ttatctccca
    90241 agtggattat gaggagttaa aaaaagctga tgatactggt agatggatga cgttgccaga
    90301 agtgctagaa cggattaaca gaaaatatga ttggtttact tctagagttt taaagaaccc
    90361 aagatataga aatattatcg atatcgagaa aaacaaaaat ggatttgtct attatccagt
    90421 tgaaggaaga gacacatatc tatttttaag aagtaaaaca cttgaatttt tagaaacaaa
    90481 tttttcggaa atcttaagga ggcaagcgga tgggaaaatt taatagagcg ctagtgttca
    90541 gcgcaccgct aatcatctac gctttaggac tttggggaag caggcaagcg ttgataggaa
    90601 cgattgttta catggtttgg atttttatgg ggcttgatga agctgaagct gagtacagag
    90661 cgaaaaagcc aaccgagggg gctgactaaa aatgaataga aaagagaaac tagaatgtat
    90721 attactatta ctcagtttaa ttctttcact aatttctcta ttgggaagtt tgtatttttg
    90781 atatcaacaa ttttgtggat ttgggttcta tttagagtaa atatcatttt tgtttggtga
    90841 ttaaggagtt tattaaaatt aattttccct acttcaaatg caaggtaaca agatatagca
    90901 cttttaggag gaatatttag cggtacagct tcagagtata ttctattatc atcgactgat
    90961 cctcctttag caattaattt cttaaatgga gtagctgacc atctgcggtt taagttagcg
    91021 gatgaaagtt ctaaattaac taacatagct ggttctgttg aatagttaga aatgattact
    91081 tttgtataaa tcatatctgc agcgaagtaa gaagcattaa gttcaacttc tagttgaggg
    91141 cgcattcctt ttatttttat ccctgttaaa aacgtactca atataaaact tattattgac
    91201 atccattgaa aaattgttaa gtgaaaaaaa ttcaaaataa acaccaccag tttttaacta
    91261 aattatacca aaaaggagag aagaaataat gcaagaatta gtaattttga aaaataaaga
    91321 agctgtgact acgagcttac aagtggcaga aagcttcgag aaaaaacatc aacatgtttt
    91381 aagagatatt gatgcactaa aaaaagatgt gtccaatttt ggacagatgt ttgtagaagg
    91441 taatgaacca gattcatatg gcagaaatcg acgagttttc ttcattagta gagatggatt
    91501 tttcttgctg gctatggggt ttacaggaaa gaaagctatc tacttcaaac aaaaatacat
    91561 tgaagcattc aacgaaatgg aagatgttat tcgcaagaat actgttcctc aaacaattga
    91621 agatatgatg atctatcaat tagaagaaat gaaagatgtt aaaaaagatg tttccatgct
    91681 taaagatact atgcgaatta gcggacaaca agagtttgaa attaagcaaa aaggaaatat
    91741 gaaagttatg ggagttctag ggggaaaaga aagccgagct tatgaagaaa tcagcaaaaa
    91801 agtattctca aaattttggt ctgaatttaa acgtaccttt tcaatcccaa gatatggcga
    91861 gttacctcgt aagagattcg atgatgctgt ttcatttatt gaaatgtggt tgccagaaac
    91921 tgcgatccgt atggaaattg atcaactgaa cagacaacag agactttttg gtgatgacaa
    91981 tgaatagagc tgaagcgcta agaataggga cggcaattgc taattgctgg tggaaatact
    92041 ataaaccaat catcctaagc caacaacata ttgacaagca aaaagcatgg caacaaataa
    92101 aaaagtgact ccgccggcaa gcaaagagtc acaaagaaaa cacatcataa ggagatttta
    92161 gcatatggaa aaagaacttt ccactctaga tcaatatttg attgatcctg attggggcaa
    92221 gccgaaaatt gaggaaacaa gtggtcgaaa aatcagacga aatcttttga cgaatgaaga
    92281 actagcttgg gatcaagatg atttaggcaa ccatgtaact atttgggatc atgtttatct
    92341 tatccatcta tcgaagcatt cgaataaacc tgaatatatt tacgtcatcg aagatggctt
    92401 gattgatgcg ctagaagagt acgacagaga taacttgatt gatatctctt attacggacc
    92461 aggtaagaaa tacattgctg aaatggaggc agaatttgat gagtgaaatc aaagggacaa
    92521 cgaactttga aaaacttttt agtcgtaagt taaataaaat tctcaagaaa aaaggaaatt
    92581 ttgattattt atcttgggct cacgcgtggg agattatgaa aaagaatgat ccacaggcaa
    92641 cggtaactat taatgagtac aaacactaca gggttgtttc tggaactcat caagactttc
    92701 ttgttgagga atataaacct tttcttatgg atgaaactgg gacttatgta tctgtctcag
    92761 taacggttaa aggacacacg gaaaccgaat tatttcctgt tttagattat cgaaaccaac
    92821 cagttgttaa accaaatgca atgcaaatca ataactcatt gaagcgatgc tttgtgaaag
    92881 cattggctct acacggactg ggattatatg tatttcaagg ggaagatatt ccaacaccac
    92941 ctagaatcga tacaaagaaa ttaaacatgc tagagacgat tctagaagct ttcaatgagc
    93001 agatgggtaa agatatgacc aaaaccttaa tcgaatatgt taatgagcag acagataaat
    93061 tagggctctt agctgataac gttgaaacta ttgaacagtt aagctatgag caatgtgcct
    93121 tgatggagcg agcaatagca gctaagagaa aagaattaga taagaagtga tatgagtgtt
    93181 taaaccatta atcgattcat attcagcggt tctgaaaaag ttcaaaggaa aagacataag
    93241 cgcaaccatc aatgaggaag tgaacattga tcgactaaag acgatgtatg acggctacga
    93301 tggtgatcga gtcattgaaa ttcgttttat tgatcctaga cgtttcaccg tacagcaacg
    93361 aaacttcatc tatgcgctga taggcgatat ttttatcgat acaggcatgc caacggactt
    93421 ctggaaggaa ttcttctact ttcgttttga aggtgtcaca gggcgcaaaa taagcctgaa
    93481 agacgaatcg aatacaactg tgagtgatgc caatgtctta gcaaatatca tcttagattt
    93541 catctttgaa catcatattc ctttcaaaga aggctatgag attttacctg cgaatcaaga
    93601 atattacttc tacaaatgca tcacaaaaag agtctgctgc atctgtggca aaacaggagc
    93661 tgacatcgat cactttgaca aagcgctagg aagacgaaag cgcaaagaag ttgatcatgc
    93721 agagtacaca tttgcagcac tctgcagaat ccatcacaca gagaagcaca aaataggtgt
    93781 gattaatttc aaaaataaat atcaaatcaa agggatcaaa ttaaaccaga aaacaatcaa
    93841 aaagttaaat attggagggg aaaaatgaca gaacatcgaa gttattatgc gattatacca
    93901 gccaacgtaa ggtacgacaa aagacttaaa ccaaatacta agttgttata cggagagata
    93961 acggccttgt gtaatgaaag aggcttttgt tgggcaggca atgagtactt tgcagattta
    94021 tatggtgtga ataaagagac catatcgcga tgggtaagtg atttgattaa gtttggatac
    94081 ttgaatcggg aaatcattta caaagagggt accaatcaaa taatcaatag gtacctacga
    94141 attaatcaat accctattga cgaaaaacgc aataccccta ttgacgaaaa agtcaaagat
    94201 aataatacat ctattaataa tacatttaat aatacaaaag aatatataag agagttaccg
    94261 ccttcgaaaa aatcgaaggc taagcccgtc cgtcataaat acggagagta taaaaatgtt
    94321 cttttgtcag atgagcagat ggagaaactc aaaacagaat tccctaatga ttaccaagag
    94381 cgaatcgaac gactgtcaga gtattgtgaa tcatctggta agacttataa aaactatttg
    94441 gcaactattc gaagttgggc aaggaaagaa aaaagtgaac ctaagaacgc aagcagtgga
    94501 tacaagcgca caggaagacg agagaagctt cctgaatggg caatcgacca agaagcctat
    94561 ctcaagaaaa aagcgctaga acgagctaat agacaatcaa aagcaccatt ctaagaggtg
    94621 gaaaaatgaa gatcgattat ctagaactaa ttaatgaaat agcgaattat aaaaagggcg
    94681 aggaattaga cgtcctgaga gacgtatatg atcaactcga agaagctgga attgaaggaa
    94741 ttaagaatga tcgttcgagt tggagtaaac tcagatacta tttcgcactc tatatcgatg
    94801 gaacgcaatt aagaaattta gcatatacca aattactatt cattgattgt gttaaaggct
    94861 tgcaaaaaca tcttaatgaa cttgagcagg tgtaaacaag atggacctaa agacatttac
    94921 agcacagatc gaattaatgc atcaagaagc tttaagacaa agtgtgtcgt acgaagacaa
    94981 gtggctcaac acatttcatg gcggacgtga gagcgcactt gatcaagtac tcaaattact
    95041 gaaaggagaa tgtcgggatg gataagaaag cggcaatgca gcgaattatc gaattgactt
    95101 attcagaaga ttggcaggaa gataaaaaaa tagttgcaga agtccaaaag ctcggtaaat
    95161 caatgtggac tgaaaagccc aaacggagaa cgccgagaaa gattgcaatc tggcatggtg
    95221 atcgaattct agtaacgggt accgctaaac agttatctga aattactggt ctgagcaaaa
    95281 atattatttg ggatagagct aggagcttat ggattgattc aaaaggaaga cagtttaggt
    95341 atgtggagga gaaataatgg acgaactaat cgcgaaagta gagcagtggg caaaagataa
    95401 gggattggat caagcggatt tcagcaagca aatgttaaaa acggtcgaag aaatcgggga
    95461 agttgccgct tctctagcta gaaaagatga acatggttta agagacggaa ttggcgatgt
    95521 agtagtaacc ttgatcatct tggcaatgca aaatgatatg gatttatacg agtgcttgga
    95581 ttttgcttat gacgaaatca aaggtcggac tggaaagatg gtcaatggtg ttttcgttaa
    95641 gtccagtgac ctgaaataat tccattaatg gaagaaataa ctgaatagga ggatagacat
    95701 gattgatgca aaacaagtgc aaaaacagaa agatggaatg ttgatgtttg aagcatatgt
    95761 tctaccattt cttaatcaat ttgaagtttt ggaatgctct gccagcggag aagaattgga
    95821 gtatgttgta attcgtgaaa ccaaagaaaa cgttcagaag ctaaacgaat ttctttgcac
    95881 tattaactgt tgggatatga tagctccagg atttttatgt ccagctatgg gagaattttt
    95941 ggaatattgt cgtcttgaag atgcaggcac tttggattta gcttatctgg tatacaacta
    96001 cctaaacatc aacacagatc atttgtggtt tggcactgcc gaaagaaaat gggtagtccg
    96061 ctaaccacca atatcaatga aaaaaggcgg tttcctgaaa gtggaattgc cgccattgct
    96121 gtaaggttct ttacgcgact caaggtcaca gaaatataaa tgcaaatctc ttttgaagtg
    96181 atccaaagct ctcggaaaat ggaagttttt tgtttcaaag aataaatgag atttgcgtca
    96241 agaacctgag agttatttcc aaaaaagctt ccaaagaacc gaatgagcta aggacatcat
    96301 gtgtaaacac ataatatagc tctcctttca cggctaatca taacatgaaa aatattcgat
    96361 gtcagtagga aaaaaggtga attatgaaaa gaatattaaa ttatcccggc agtaacagat
    96421 tctgcaatta aactccgaag ctgatgtatc agtatcaact gtagaatatt atgagcgtgg
    96481 agaaagtcaa gcagtcacaa atgtaaaaat cgataacgtc aacggtctta tctgtttaga
    96541 tgaaggcgat agtatgaatg aaattgctgc agaccatgaa ttatcagaaa ctgctttaat
    96601 tgatcaaatc gaattagcta gacaatactt tgttccatat gcagatacct ggtccaagca
    96661 taagaatgac atcatttttc cagaggaaca atgagagcaa ctgatccagt aattatcctt
    96721 gaggaagcca aatttatttg gactcacgaa gagatagagc aagcacgctt gctcttttct
    96781 caaggagtta agccgagcaa agtagctgaa ataatgggtc aaaagattct tgatgtcgga
    96841 ttgcttttgc tccatctagc agaaaaaatt tgatttgagg tgaaaatgat gattcaactt
    96901 gcaggcatcc aaacagggaa aatttatttt tctggagaaa gcaaaagcga agccaaccaa
    96961 tggctattga aaacttacac gaacaataag aagctaagga aaaaatatcc tgatttgttg
    97021 ctaaaggatg atcagattat gccggaaccg atgattttga cccgtaagga gggaagttga
    97081 aactaaaaaa ccagccgtgt gggctggagt tgctatttct ttttaataat gagtttttct
    97141 aaatttaatt cattctcacg agtttgcgtc caataatcag aataatattt taattgttta
    97201 agagtaggaa tgtcgtcttc ggtaaaatta gaaaataatt ctggagaatt atcttttttt
    97261 aattgttcta atcctgattc tttaaaacgt tgttcaacga gttttactaa attgttgata
    97321 ttcatgataa atcacctttt taaatttaat ttcgatttga ttaatcgata caagtattat
    97381 atcaaataaa aaagctgatt tagggggtct tacaaaaaca ctaaaatttt ttcaaaaaga
    97441 ggaggaacgg tggtgaaagt cagagaacaa ttcaagatag tgagcgacga aggtaatgtt
    97501 tacaaaataa agatcgttaa tattaatgaa tatcgagaag cagatcacaa atatttggtt
    97561 gacttataca tgaacgataa atatttggga gaaggatttt gtggagattc actttttgat
    97621 gatgagcgaa ttttgaagga ggaaacagaa tgatccacga actaaaaata ctaccagaat
    97681 attttgaagc agtgacgagc ggacgcaaac aattcgagat ccgcaagaat gatcgtgact
    97741 tcaaagttgg tgatcagtta atactacgtg aatataaaaa atacattaaa catgaattac
    97801 ctggactaac gagaccaaca tttagttaca ctggtgactc atacaaagca gagatcactt
    97861 atattactga ttacatgcag aagtccggat atgtagtgtt ggggattaaa ggggtgaatt
    97921 aaatgaaagt atacatctta gctatcacag agggcacatg gatgttccca gtcggttccg
    97981 gaaaaatcta taaatcaaaa acagctgctt ataaagcatt tgaaaaatac aaaaaagaaa
    98041 acggtggcgg cactaacgca aagattctag tggctgataa ctggcatgaa gaaggtgaac
    98101 gtaattgatt tacctgttca ttttcgtggt actaactatt tttatgctag taatcttatt
    98161 caaaaaaaga tgagtaaaga cgaacgaaaa attctggcca acttttattt agtattaaaa
    98221 atcgaacaaa atgtgttttc ggaaaggaga attgtatggg aaaaacaaaa tcaaagatta
    98281 agaagaaaaa acgacgtttg gaacaaaagg caatccagaa tggaacggct aagaaaaaat
    98341 aaaaaagcta cccctttcga gatagcagcg caatactatt ctaccataag gggtggcgtt
    98401 tgtgagattt cattggttaa aagattacca agaactagat gagcagattc tttacttaaa
    98461 gtggaatctt aataaaagta agcttgaatt gaatcgatgg gtctgtggtg atttagcaaa
    98521 cgtccgcatc gaaaagaatt cgagaacttc ttctttagaa gagaatatcc aaaagataga
    98581 aaatgaattg gaattgttga tcgagcaaaa agaagaaatg ttattgctga tagatagctt
    98641 ttctggtatc gataatcaaa ttgttaagat gaaatatgtt gatcaaatga gcttagaaga
    98701 tattgctgaa tctgttgggt atagctcatc gtatgtcaga cagcgacatg cagaaattag
    98761 aaagacattg aactttttag atgagtatga acacagacaa gctgaccgat tgaaaaaaga
    98821 aaacgaaatt gatttttaca atagcgagaa gtacaaagaa caactctctt tattctaaaa
    98881 ttacactgtt cactaaatgt tcggtcattg tagctatgta aacattgtta gcagcatgat
    98941 attctattag tgtcaaaaaa atatgaaaga gccaagatat cccaaccgtt ttattaattg
    99001 gtatctgtgg ctcttttatt cttttaatta gtagttggca taaagttatt tccatttata
    99061 aattgatcag ctaaatcagc atcataatca gccgcgataa attgcgctgc tgatttaata
    99121 aatgcatcca tatcatgaac atctttatta gtatgtctac gaacatagtg cgtttcatca
    99181 ttaccaatcc aagtagcagc tttggctaat ctttggagtt taggaaaatc attcaaataa
    99241 ttttcaattg ttttacctaa taacattttt tttattttat cttcatcctc tgaattttta
    99301 gatattgcat aatctttaat tagaaattct agagcttttc tataaccaac tccagcaatt
    99361 tgttccaatt gctcagattt agcttgtgtg gcttgagtat aaatatcaac aaatgtagga
    99421 gaaacttttt caatattttc tggtaaatct attttaatcg gcggacggta ataatcttta
    99481 attaaaatat tttcagaata tccttcatct tcattaaacg tatttataaa ttgtaaacta
    99541 taaaatttgt tgcactcatc atttatacac tgtactaata cgccaaagat tctatcatta
    99601 tcgaacgcac tatatgatga aaccccaaaa tacacatacg gagtcattat atttccgcaa
    99661 tgcggacaac tatttggcaa ataaattgtc tctgtatttt gacgatcacg atacttaata
    99721 ttaacttctt gaagcattaa aacacctcgc atctttttta taaatcatac cacaaaatat
    99781 ctgataggag agtaaacaaa tgaatgattt tcatgaagcg gtacttagta ttgaagtaga
    99841 atcaagtttg gctaaagttt ataagaaagc aattgaagca gagaatagtc cgtacagaga
    99901 aaattggaat ggtaatcatg cacatgtgca agtggagaat gatgattaca gaactggaat
    99961 gaatacgtta gttatttctt tattgtcaca cactctaccc aatctgcagg aaacgattga
   100021 atggtatgag cgaatgggcg caaaagtaat ccgtacaaat tacaaaggag agaattaaaa
   100081 tggcaatgat caaaattaga acatccatta gtggaacaga gtattgggat tcagaaaaga
   100141 aaaggacagt agttgttccg aaagatcaag aaccaaattt tgaagtaaaa gaagaaaaag
   100201 gaattttgag tgatggcaaa tcatttgttg ctgtcaatgg cgaactcata gctcatagca
   100261 gtgaaattct tgatagcgat ggaaacactg ctgctaattt tgatggagac gaagctacta
   100321 atgatcagtc cactgaagat acggatgaac tggacaatat gactgcaaaa gaattgcgtg
   100381 catatgctaa gaaacatggt attgatattc ctggtgctat ccgtgcaaaa ggcgatatca
   100441 taaatcttat tcgtgaagta gaatgaaata ctgtcagttt gacggatgca cgaacaaaat
   100501 agcaaagggt atctactgta ctgaacacaa gagatcaagc agatcacgca agaagaagca
   100561 gcaagcaaag tctgtttatc atcatgagaa caaaccattc tatcgaacgc aagcatggaa
   100621 agatatgcgt caatttattt atgaaagaga aggtggtcat tgtcagcggt gtggtcagtt
   100681 catatttgga aagagagcac acgtccatca cattgtacca atcaaagaca acgaactgct
   100741 taagcttgat ccaaacaatc tcatgctatt atgttcaaaa tgtcatccaa ttgttgaaaa
   100801 cgaaacggaa gacaaaaaag tttttccttc gtatttcaat tgaagccccc ctattcattt
   100861 tcaaaatttt ttcgcgtggg gagatagggt agcggggagt cacgcgcatc gttaggtcaa
   100921 atttttcaaa aaacaaaggg gggtgtatac aaaaatgacg actaaagcgc aacgtaaagc
   100981 gattattgat gaaaaagtaa gtgctgaaaa agctcgtatc ttagaaataa tgaatttgtc
   101041 tgatttgtac accatcactc ttgatccatt aatcgaatca tacttggata tttttgaaat
   101101 ttaccaacac aaatatttat tgtggaagga aaaaggattt ccggagacgc aaaaattcac
   101161 gaataaatca ggagctacta atcaatcaaa acatccattg gcacaacaag tagaaacttg
   101221 ggcagataag aagatgaaag ctctagattt attaggatta acaaacaaag caaaaactgg
   101281 tagactaatt gctggaggat cgaccgcaag aaaagatgaa gaaattacac gcccagaagt
   101341 aaagccagta gatgaactag cagcgcacag aaataaatgg cgtaagaagg caggtgctga
   101401 aaaatgattg aacctggtgt aaattatgct gatttatttg caaaagaagt aagaaagaaa
   101461 cctaagaagt atcctaagac cgttcgttta gcaatagatc gctggtatca gtggaaaaaa
   101521 agaaaagata tttggtttga tgtagatcgc gcgaatgaaa tgatggattg ggtagaatca
   101581 tttattgttc acacaaaagg agaaatggtg ggaaaaccgt ttcttttaga accctgggaa
   101641 aaatttattt attcttggat ttatggttgg gttaaagaaa atgaaaaagg ccaaattgta
   101701 cgcgttactc gtgaggctta tgtccagatt ccaaaaaaga atggtaaaac attgattgct
   101761 gtcggttcat taggatatgc aatgtacgga gaaggggcgt tatcagttga ttgctatgct
   101821 tgcgcatctg attttgctca agcgcaatat gctgccaaac cttttgcagt tacaatctta
   101881 aacaatccaa tcctacttga aggaactaaa atatttaggg ggccaaaggg aactgtttct
   101941 agtattactt atgactatat tcatgaagat atggcttact caaataaatt tattgttcaa
   102001 accaagaata ttgataatat cgagggatcc aatccatatt ttgtattgaa cgatgaattg
   102061 cataaacagg agaaaatgga acagtatgac aattttaagt ctgctcagat atctttacca
   102121 cagccattga tgtttaatat ctcaactgct gggaaaggtt cgtcgtctgt tggaatgcgt
   102181 gtatatcgcg aagcaaaaga agtgttgaaa cgtgatgata atgattcaaa ctttgttcta
   102241 atctatgagc caaataaaaa ttatgattgg acggatagaa aagtctggga aatgtgcaat
   102301 cctaactggg gaatatcagt cgatttatct gctttagaat cggcatttaa aacagcgcaa
   102361 cggtcagctc attccaaagc tgaatttcta acgaaacact tggatgtatt tgtgaacggc
   102421 gcggataatt tctttgaaca ggatcaagta gagccatgtt tagttaccac acaagaactt
   102481 ggtgatttaa gtggcgaacc atgttatatc ggtttagatt tatcacgtac acgagatttg
   102541 acctgtgtat ctttaaactt cccaacatgg gatgaagatg gtaaagcggt tcttaaagta
   102601 aagcaacttt attttattcc gaatgaagat ttagagtttc gagaaaaaga agataatgtt
   102661 ccttacagtg atttggctga acaaggtttc gttgaatttt gcgacggaaa aatgattgat
   102721 caagatcaga ttttgcagta catagaggac tgcatgaatt tatatgatat tcagcaagtg
   102781 aattatgatc cagcgatgag tgacaaactt gttgagaaat tagaaaactt aggattggaa
   102841 tgcgttgaag ttgctcaata tcctaaagta ttgaatgctc cttttgacga tgtcgaacgg
   102901 ttgttttatg agaaacgaat tcaatttgat aatccattat tcctttattg cactttgaac
   102961 gttgtagcaa ttactaacat caatggacaa aaagcgccaa gtaaacgtca atcaaagaaa
   103021 aagattgatg ggttcgtggc gtttttgtgt ggtcataagg aaacgatgaa tcaaatgaca
   103081 gatattgatt cagatgagtt agatgattac ctaagttcca tctatagata aatagaaagg
   103141 cggtgaaaaa aattgaaatt acgtgatcgg ttatcgaatg cagtctattc ttttatggaa
   103201 aaacgtggat atatcgagga tatttttgga cactacacac gttatggtca aagatatgtg
   103261 acggattcat ctatcatgga atcttctgat gtttatgaat tagttcaaga catatctaat
   103321 caggtggcat tggccacacc aattgttatt ggtcccgacg gcaacgaagt caaagatcat
   103381 cacttactaa atattttgaa gagtcccaat gattatttga caggattcga atttaccaaa
   103441 ttggaaacaa atactttatt gatcaatggt gagacattcc cattaacgga tagggatcag
   103501 cttcatttgg cgtacggtgt aacaactaaa atcaatgaac gacttcaaga agaatttgaa
   103561 atgaatggtc aaaaaatacc tggtcaaatg attcgacaca ttaagaacat cggaactgat
   103621 tcattaaaag gtgctggaat aattgatctt gcaagaaaca ctctagaagg cgttctgagc
   103681 gctgaaaaag ttttgacgga caaatatact aaaggcggtt tacttgcgtt catgcttaaa
   103741 ctagacgccc acatcaatcc aaataatagc gcccaaacaa aaattgtcaa agctatattg
   103801 gatcaactgg aaggaacgca aaatgagagt gatcattctg ttaagatgat tcctttggga
   103861 aaaggatatt ccatcgagac attaaaaagt cctgttgatg acgcggcaat tttgaattat
   103921 ttaggtgttt acaaaaaaga cttaggaaaa tttctaggaa tcaatgttga tacgtatcaa
   103981 tcgctgatga agacagatat tgaaaaagcg atgatgtatc tgcacaacaa agcaatcaaa
   104041 ccaatattga aaaacaagag cgaacattac accgctcttt tttttatgcc taattctggc
   104101 tatagagtgg aatggaaaat taatattttg gattttgttc cttactcaac aaaaacaaat
   104161 attggctaca acatcgttcg taccgggatt acaagtccag ataacgtggc agaaatgctt
   104221 ggttttccta aacagaatac tccagaaaca caagctatct atatttcaaa tgacttatct
   104281 aggattggcc agaaaaatgc aacagatgat tccttaccaa cgaatgatca agacttgaaa
   104341 ggaggtgatg gaaatgaaga agaaggaaat tcgcacgatt gacatcacca atctttcaac
   104401 acgttccgat gaagaaactc atacgaggac cattagcggc tacgctgctg tattcaacag
   104461 tcaaacactt ttatgggatg acttaagcga agtgattgtt cctggtgcat tctcaaaggc
   104521 aattagtaat tcggatgttc gttgtttgtt caatcacgat tggtccaatg tgctaggacg
   104581 tactaaaagc ggaacccttc gccttgaaga agatgaacgt ggtttgaaat tcgaagttga
   104641 tttaccggac acaacggtag caagggactt agttaaatct atggaacgag gagacatcaa
   104701 ccaatgtagt tttggttttg tgccgactga agaaacgtgg gactacaatt ctgaaccaat
   104761 gcttcgaaca atccatgaag tggaattata cgaggtttct attgtgcctt tgccagcata
   104821 cgaagataca gaagctgcat taagaagtcg tgatgaatta gaaaaaaacg tcgaagaaag
   104881 aaaaaaatta atcaaaaaaa ttaatcaagc gctagaagcg taggaggaaa aatacatgga
   104941 taaagaatta ttgaaaaaaa tgaaggcacg tcgtgagcaa cgattgactg aattacgtga
   105001 aaaagttgaa tcaggagaat tacgcgaagc agatttagaa gccgtgaaag aagaaattga
   105061 cagtgttatt gatgaattga acggaattaa agacgaatta ggcgcagatt ctggaactga
   105121 tgaaacagac gacaatacag atgatcaatc gaatagtacg gattcagacg aaagccgttc
   105181 tggtgaagac aacgatcaag aagaagattc agacagtgaa gatagttcag aaaatcgttc
   105241 tggaatgatt actcaacagc aacgagatgg attacttgga tcaattaaga acggattgga
   105301 ggcacgtgca aaaatgacca agaaacaaaa agatcaacaa ctacgaaaag catttgctaa
   105361 ttttgtagct ggaaatattt ctgaagcaga agctcgagct ttagggattg aagctggcaa
   105421 cggttcagtt actgtcccag aagtaattgc atctgaagtt attacttatg ctcaagaaga
   105481 aaatttactt cgtaaatacg gaacagtggt gcgaacatca ggagatgtca aatatccaat
   105541 tcttgtgaag aaagcagatg cgaatgtaaa caagaaagag cgttcaactg atattgctga
   105601 aacagctatt cagtttgatg aaattttgct taatcctgcc gaattcgatg ctttggcaac
   105661 agtaactaaa aaattattaa aaatgtctgg tgttccagtt gaagatattg ttgtggaaga
   105721 attgaaaaaa gcttatgtgc gtaaagaaat caattatatg ttcaatggtg atgacgctgg
   105781 aaatgaaaat cctggtgcat tagccaaaaa ggctgtagca tttaaaaaac ctttagatct
   105841 aactgcttca ggtgctgggc aaaaattata tgatgcatta atcgaattta aaaatacacc
   105901 agtgacagaa gtgatgaaaa agggacgctt tattattaat cgagctgctt tgactgccat
   105961 tgaaaaaatg aaaacagatg atggatttcc tttgttgcgg ccattcacac aagcagaagg
   106021 tggaattggt taccaattag ttggctatcc tgtggattgg acagatgcag cagataaaaa
   106081 gggtgaacca gacacgccag ttttatattt tggcgatttt tctgcattta aaattcaaga
   106141 agttattggt gccttggaaa ttcaaaaact tgttgaaaaa ttctctggta aaaatcaaat
   106201 tggattccaa atttacaact tgctagatgg tcaattggtt tattctccat ttgaaccggc
   106261 agtatatcgc tacgaaatta caaaaccagt tggtggttaa gatggaagag caaactaaag
   106321 aattgtcttt agaggaaaaa ttcaaatcac atattcattt tgaagagggc atggatgatt
   106381 ctttgctctc tttttattta aatatggcaa aagattatgt caaaacagca actggtggcc
   106441 aacaagaata tcttattttg atggttgccg gcattgccta tgaatataga gtttcagagg
   106501 atgaactcga caaagctatg aatgccatga cgccatttat cgtgcaagga gcgattcaaa
   106561 atgccgaaga gacagactaa taatctcaga tggaaagccg aattgctaga catcaaaaca
   106621 ggaacagacg gaaacgatcg tccaactaca atttacgaat ttaagcgtct aatattctat
   106681 gaagaactcg gtgtgacttc tcaagaaaaa tatttatcac agcaagccaa gacagacgtt
   106741 gtcagacgaa ttaaagtcag atgggataaa tccatcacag agaaattaag tgcgctcaaa
   106801 attgattctg taacgtataa cattactcgc atttatacga atcccgatgc aagagaaatg
   106861 gagttgagtt tagcttatgt cgattagctt tgatgaattg aaaacagcgc tgaaatcaac
   106921 aaagttagca gtgttcagag acaaagccag attagggacg atgtatccat acattgtgta
   106981 ctcaaatgtg agtaacagca aaaaaatggc atccggtaaa gtctataaaa aattacctta
   107041 ttaccaagtc tcttttttta cacttggaac agaacaggat ttagttgtta ttgaacaagc
   107101 gctgcaaaat gctggcattc catattcaga ttttacaggt atacaaggtg atgagaacga
   107161 cgataccgta accaactatt acacatatgt gaggtgtgtg gaaaatgcca agtaataaga
   107221 atggtttttc tgaaatatcg gattatttag gaaacctttc aaaagttgat ccgaaaaaat
   107281 tatcgttgga atctttagaa gaagcagcta acttttatct aaagcagttg cttcctaata
   107341 ttcctaagtc gctcttaaaa aagaaacata tgcgcgatca aataaaagta gtagttgaaa
   107401 acgatcaagt gaaagttcaa tttgaagaga cggcctttta ctggcgcttt gccgaaaatg
   107461 gcacaacaaa tcaacgtgcc caacattttg caagtggtac gtatgaacaa aacaaagaaa
   107521 aaattgaaga aattatgact agaaaaatac ttgatttatg ggaagggtga ttttaattgg
   107581 gaaaacaaga tactttttat tttgaaggat tggacgacat tttaattgcg atgatggcaa
   107641 cgccagattc tgttggaact gcaccgactt atagtgaagt tttacgattg ccaattgcca
   107701 caaaaatcgg tgtcaaaggg aatggaacag cattagaaaa atgggcatcc agcaaaatgt
   107761 ttcgtcgtgt gtcgcgagaa acaaaacatg aacttgcgtt ggatcacgtg ggtattccga
   107821 tagaagtgat ggatgaaatc aaaggattag ttgctaaaag cggagtaacg tttagcaaaa
   107881 ataccgcacg agaatttccg tacttcgcct ttggatttat tggaaatatt gaaaatggcg
   107941 gtaaaaaagc agtttggtat cctaatacac aactatccaa tgtgattgac gaagagtatg
   108001 ccactgcaga ggaagaaaca aaaattgacg atgtaactgc aaatctggtt tccatcggac
   108061 tgaaatacaa taatgtgatg tatgcaagtt ttgattcaaa tagagacgga gcttctctag
   108121 aattatttaa taaattcatt gctcaacctg tatacgatga agaacagtgg aaaacattgg
   108181 ctaaagttgg aggtgcgggt taatggctcg gttatctgat tatggaattc acgttgaaga
   108241 cttaaaaaat tctgctgttg taattattca aggcgcagaa ttccctattt catttactat
   108301 gcaaacgatg gaatttatag cagatgtgta tggtggagat tattcgcaat ttgaatctga
   108361 tatgaacgcc atgctatcta aaaaagaagg acaaatttct tctgctaact tatcgcctag
   108421 tgatctaaaa atcatgcgtg ccttgattta tgccatgctg cgtactggtg gtttagagga
   108481 agatccagaa actattttca aatttttggg aatgagtgga gaggtgttgt ctgcttatag
   108541 tacctgtatg gaaatttttg ctagccagac atttcaggtg gaagacctaa aaaaatccaa
   108601 gaagccacaa gactttcaaa aagcgcaagc aaaaagaaag aaaaacaaaa agaatcggaa
   108661 gagataggaa ctccttggag tttttatatt tacgttgctc tcactctatt gaattggagt
   108721 gagagtttct ttttaaagtc tacacctaac ttgtggctca aatcttattt acagtggtta
   108781 caacaaaaca ccgattttga accacctcaa tctgtaacta tggataaatc gccttggtgg
   108841 tagaaaggag cgctaagata aatggctggt aaagaatctg atgtcgttct taattttaaa
   108901 acgaatggcg aagtcagtta ttcgaaaaca atcaaagaaa tcaacaaaga aatgaactta
   108961 gccgctgccg agtacaaaaa ccaagtgtct gcgatggaca aggatgcaac tcaaacagaa
   109021 aaattgcgag cggctaaaca aaaattagaa aaacaattag gattggctga acaacgatct
   109081 caaatgctga gagaggaata tgaaaaatct gtcaaagaaa ccggtgaata ttctgctgaa
   109141 tcagaaaaac tttataaaca attactcaat tctgaaaccg gagaaaataa acttcgtaca
   109201 gcattagaac agacgaacga tgcacttaaa gaacaaggtg acgtttctgt tgatacagca
   109261 aaaaaactcc agaaaatcga agaaacaggt gagaaagtaa aaggcgttgg tgaaaaaatg
   109321 tctgttggag taaccgcgcc tattgtagcg gcaggagcag caggacttgc agcatttggt
   109381 gaagttgacg aggcacttga taccatcatt acaaaaaccg gagcaacagg tgatcaagct
   109441 gatagacttt cacagtcttt caaaaacgtt ggttcaaata ctcatttacc tttacaaacg
   109501 gttggggaag ctattggtga ggtaaataca caatttggat tcatggataa aaaactggaa
   109561 gattcaacca attatctcct acagtacgct gaaatcaatg atacagatgt ttcgcaatca
   109621 gcaatatctg ctcgacaagc tattgatgct tatggactag aatatgatga tttgaattct
   109681 gtccttgatg taacaacgaa aacatcgcag aatactggtc aatctgtaga cgacttgatg
   109741 caaaaagcaa ttgatggcgc accacaaatt aaacaattag ggttgagctt tggtgaaggg
   109801 gtcactttac ttggacaatt tgagcaatct ggtgttgatt caagcgcagc tttaagtagt
   109861 ttatctaaag caacagtggc ttatgcgaaa gacggaaaat ctttaagtca aggactagaa
   109921 gaactacaag acaaggtaaa aaatgcaggt tctgaaacag aagccatcaa tgcagcagca
   109981 gaagtattcg ggactaaagg cggtcctaga atggccgatg caattcgtag aggtactttg
   110041 aacctggaag atttagcaaa aactgctgga gaaagtgggg gagctgtagg agacacattc
   110101 gatgctactc tcgacccaat tgatcaagcc gatcaagcta tgaacaatgc aaaattagca
   110161 atggctgacg taggtgaagc agtccaagta agccttttgc ctttttttga aaaagcaact
   110221 tccttattac aggaattctc taaatggtgg gggtctctag atcaagatac aaagaattgg
   110281 atcataacaa ttgctggtat agcggcagca gttggaccag tactaatcgt tcttggttca
   110341 cttatgggat ctgttacaaa aatcgttggg gaagttaaaa gttttatagg agtttggcaa
   110401 ggacttgctg gtttatttgg aatgtcggga ggctggtttg cattagcagt tatagctatt
   110461 ggcgcattag ttactggact aatttgggca tataataacg ttaaatggtt tcatgatgga
   110521 gtgaattctt tcttcaaagg tgtttcagat gtagctgttg aaatatttaa ttttttaagt
   110581 ggttattttg gtggattttt cgatggtgtt atagcaaatt tcaataattt ttataatgct
   110641 ggaaaacgaa ttttcagtgg ttttctagat tttatcactg gagtatttac agggaattgg
   110701 tcaaaagcat ggcaaggtct agttgatatt tttggaggta ttttcgatgg tattgttgct
   110761 gtagggaaag ctcctattaa tgccatgatt ggattgatca atggatttat tggtggattg
   110821 aataatataa agataccaaa atgggttcct ggtgtaggtg gaaaatcatt ttctatttca
   110881 aaactgcctt atttagcaca aggcggtcat ctaatcaatg gacaagcgat tgttggtgaa
   110941 gctggacctg agttactgac tgccaagaat ggtaaaacca cagttactcc attatcagac
   111001 gaagaaaaac gcaaagggat cagtggaaga gtttctggag gtagcattga acagcatata
   111061 cacattggca aagtcgatgc aaacaatcca tctgagttag atcgtatgaa tcgtaaattt
   111121 gctaaagcaa acaaacaggc tattcgtgat ttgggaggtg ttcctatttg agtcgacaat
   111181 ttatgaatcc agatgaacca aattttattt ggaaaaatcg gaatgcagta attgatatga
   111241 attgcatcat tgaggcagag cttccagata ttatgccgaa caagcgatac gaaacttaca
   111301 cgattcaggg ccgaagcgga gaattgacgg agacgtttga tgactatgaa ccttttgatt
   111361 tggaaataga agggatcact attccacatt cgaaactgag agaagtcaaa cgatggctca
   111421 ctggtaaaag ccaattaatc acacataatg atccagacaa gtatctagag gctatctgca
   111481 gcatggataa agaagtccct ttcgaaaacg agtggggctt cttttataca ttcgatgtta
   111541 cttttcgttg tcagccactc aaaagaaaaa tcggtgaagc acctaaaatt tttcattcta
   111601 gtgttatgga tatttttgat catggtgacg aaattgcaca tccctatctg gaaatagaat
   111661 cgaacggagg agatataacg atcgctgtcg gtgataaaag cctaacaata cttaatacgt
   111721 tagctgcaac aatcgtggtt gatactcagc ttggaaaagc aatacaagaa ggtttgaatt
   111781 tatttacgcg tggtgattgg ccagtattgc agcctgaatg gaatcaggta aaaatatccg
   111841 gaaaatttaa agaagtgcgg ttttggaata ggagtgtgta tctgtgacgc aagaatttat
   111901 ttatgcttat aaaaaaatgc cagatgattt gagcgtgaac ggagcgtcgt tagttgattg
   111961 ggaagatttg ccagaaatca atcgtgtgct gaatggccaa tatcgttttt atggtaacta
   112021 ttcaagaagc ggacagtatc gctcttattt aaaaaaagga aattttataa aagcgaaggt
   112081 accagatgga tcatggcaat attttgaaat ttataatgtc aaaaagaatt tgacctccgt
   112141 ttctgtaaca gctcggcata ttggttttat ggccaataag aactttattg tcaagtcgtt
   112201 tacggataac ggcaatgggt ctcagatcat gaccaatctt aaaaacagtt tggcatttga
   112261 tcaaaaattt aactatcttt cgaatgtagg gacaacgcac caatttacag caagacaagt
   112321 cgcgccagtt gaagcaatca ttggttcaaa taacggtaat caaaatttga ctggcgtgac
   112381 tagcgcggaa cttgatatgg ataactatga tttgaaactg gtaaaacaga ttggatcaga
   112441 taatggtttt cggattgatt ttggcatcaa tttagaagca atcgaagaag aaattgatga
   112501 agaatcaatt gtcaatagtt tgtatttggt tggcggtgtt cctgataacg attatgatga
   112561 agacaaagaa cctatcgaat atggttattt agaaattgat ggagtaacca acgagaatcg
   112621 acgtattgcc aaacgtgaaa acggagattg taaaacagtt gatgaattga tcaaatgggg
   112681 caaaacctta tttgacaatg atcgtatcca tgagccaaaa gctactcata cagtcagtat
   112741 ggtggcgttg gaacacacac tcgaatacgg tgacatgtat caagagctag cgtctttaca
   112801 ctttggtgat gtcgctcatg ttagggcgaa agagctagat atcgagataa aagagcgtat
   112861 ggtcgaatac acttatttcc caacgcttgg gaaatataag gatattgttt taggtaatga
   112921 tttatcactg tacacttcgg cagtaaatac tcaagcacaa gaattgaaaa agaaaatcga
   112981 caatcgaaca gaaacgttag ttcaaaatgt gttgaatgcg acggcatgga tcactggtaa
   113041 ttctggtggg catgtcgttt ttcgtccaga aaaagctcca tcagagattc ttatcatgga
   113101 tactccaaat gtggcgaatg caaagcgagt gtggcgttgg aatttaaatg gcttaggtta
   113161 ttcagacaac ggagtaaatg gcccgttcgg tattgctatc acatcaaaag gagaaattgt
   113221 tgctgacttc atcaaagtag gaacaataaa tgcagaagta ttcgaaactt cctttaatgc
   113281 ttatggtgat gtgttaaaac ttgtaaaagg cacgcttcaa atttggaatg aaaacaaaaa
   113341 aatcatggag ctaaccaaaa aaggtatgga attctggaat agaaaagaat ccattggaac
   113401 gatcggaaca acagattcag caggaaatcc atttccaaat gctgtaacac ctacacctct
   113461 tgaggaaaat tctttggtaa tacgtacaaa tggcgatgga aaatacattt taatttctcc
   113521 aactgcagaa aaaggatttg tgttattagg aaacggaaaa gcatattatt tcggtgattt
   113581 agatattcag ggaaaactta ctgttagagg taaagaagtg ataccaggac aaaatggcgg
   113641 tccatctggc ggaggagaaa cacctggtgg gtatcctgat gaattaaaaa cagatgcaga
   113701 aaagagagct tggagaat
//
LOCUS       DBBGSP010000002       107269 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000002 DBBGSP010000000
VERSION     DBBGSP010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 107269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 107269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..107269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.002"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(7..1581)
                     /locus_tag="ACIZE9_000138"
     CDS             complement(7..1581)
                     /locus_tag="ACIZE9_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HGC6092039.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(1836..2345)
                     /gene="mreD"
                     /locus_tag="ACIZE9_000139"
     CDS             complement(1836..2345)
                     /gene="mreD"
                     /locus_tag="ACIZE9_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGC6092040.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(2349..3203)
                     /gene="mreC"
                     /locus_tag="ACIZE9_000140"
     CDS             complement(2349..3203)
                     /gene="mreC"
                     /locus_tag="ACIZE9_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGC6092041.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(3358..3996)
                     /locus_tag="ACIZE9_000141"
     CDS             complement(3358..3996)
                     /locus_tag="ACIZE9_000141"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGC6092042.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(3997..4647)
                     /gene="rpe"
                     /locus_tag="ACIZE9_000142"
     CDS             complement(3997..4647)
                     /gene="rpe"
                     /locus_tag="ACIZE9_000142"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGC6092043.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(4660..5559)
                     /gene="rsgA"
                     /locus_tag="ACIZE9_000143"
     CDS             complement(4660..5559)
                     /gene="rsgA"
                     /locus_tag="ACIZE9_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGC6092044.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(5724..7793)
                     /gene="pknB"
                     /locus_tag="ACIZE9_000144"
     CDS             complement(5724..7793)
                     /gene="pknB"
                     /locus_tag="ACIZE9_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HGC6092045.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(7790..8530)
                     /locus_tag="ACIZE9_000145"
     CDS             complement(7790..8530)
                     /locus_tag="ACIZE9_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGC6092046.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(8543..9901)
                     /gene="rsmB"
                     /locus_tag="ACIZE9_000146"
     CDS             complement(8543..9901)
                     /gene="rsmB"
                     /locus_tag="ACIZE9_000146"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGC6092047.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(9901..10839)
                     /gene="fmt"
                     /locus_tag="ACIZE9_000147"
     CDS             complement(9901..10839)
                     /gene="fmt"
                     /locus_tag="ACIZE9_000147"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGC6092048.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(10832..11323)
                     /gene="def"
                     /locus_tag="ACIZE9_000148"
     CDS             complement(10832..11323)
                     /gene="def"
                     /locus_tag="ACIZE9_000148"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGC6092049.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(11338..13746)
                     /gene="priA"
                     /locus_tag="ACIZE9_000149"
     CDS             complement(11338..13746)
                     /gene="priA"
                     /locus_tag="ACIZE9_000149"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGC6092050.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(13999..14304)
                     /gene="rpoZ"
                     /locus_tag="ACIZE9_000150"
     CDS             complement(13999..14304)
                     /gene="rpoZ"
                     /locus_tag="ACIZE9_000150"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGC6092051.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(14309..14923)
                     /gene="gmk"
                     /locus_tag="ACIZE9_000151"
     CDS             complement(14309..14923)
                     /gene="gmk"
                     /locus_tag="ACIZE9_000151"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGC6092052.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(15410..15694)
                     /locus_tag="ACIZE9_000152"
     CDS             complement(15410..15694)
                     /locus_tag="ACIZE9_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092053.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(15712..16602)
                     /locus_tag="ACIZE9_000153"
     CDS             complement(15712..16602)
                     /locus_tag="ACIZE9_000153"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HGC6092054.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(16622..16840)
                     /locus_tag="ACIZE9_000154"
     CDS             complement(16622..16840)
                     /locus_tag="ACIZE9_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGC6092055.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(16810..18510)
                     /locus_tag="ACIZE9_000155"
     CDS             complement(16810..18510)
                     /locus_tag="ACIZE9_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HGC6092056.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            18777..19550
                     /locus_tag="ACIZE9_000156"
     CDS             18777..19550
                     /locus_tag="ACIZE9_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092057.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(19631..20200)
                     /gene="thiT"
                     /locus_tag="ACIZE9_000157"
     CDS             complement(19631..20200)
                     /gene="thiT"
                     /locus_tag="ACIZE9_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HGC6092058.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(20266..20368)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(20374..21345)
                     /locus_tag="ACIZE9_000158"
     CDS             complement(20374..21345)
                     /locus_tag="ACIZE9_000158"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGC6092059.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(21439..22812)
                     /gene="glmU"
                     /locus_tag="ACIZE9_000159"
     CDS             complement(21439..22812)
                     /gene="glmU"
                     /locus_tag="ACIZE9_000159"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGC6092060.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(23315..24133)
                     /gene="purR"
                     /locus_tag="ACIZE9_000160"
     CDS             complement(23315..24133)
                     /gene="purR"
                     /locus_tag="ACIZE9_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGC6092061.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(24300..25124)
                     /locus_tag="ACIZE9_000161"
     CDS             complement(24300..25124)
                     /locus_tag="ACIZE9_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGC6092062.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(25097..25777)
                     /locus_tag="ACIZE9_000162"
     CDS             complement(25097..25777)
                     /locus_tag="ACIZE9_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGC6092063.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(25800..26738)
                     /locus_tag="ACIZE9_000163"
     CDS             complement(25800..26738)
                     /locus_tag="ACIZE9_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HGC6092064.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(26983..27834)
                     /gene="ispE"
                     /locus_tag="ACIZE9_000164"
     CDS             complement(26983..27834)
                     /gene="ispE"
                     /locus_tag="ACIZE9_000164"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HGC6092065.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(27988..30561)
                     /gene="mprF"
                     /locus_tag="ACIZE9_000165"
     CDS             complement(27988..30561)
                     /gene="mprF"
                     /locus_tag="ACIZE9_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HGC6092066.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            30702..31508
                     /gene="proC"
                     /locus_tag="ACIZE9_000166"
     CDS             30702..31508
                     /gene="proC"
                     /locus_tag="ACIZE9_000166"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGC6092067.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(31587..33143)
                     /gene="rny"
                     /locus_tag="ACIZE9_000167"
     CDS             complement(31587..33143)
                     /gene="rny"
                     /locus_tag="ACIZE9_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGC6092068.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(33554..34603)
                     /gene="recA"
                     /locus_tag="ACIZE9_000168"
     CDS             complement(33554..34603)
                     /gene="recA"
                     /locus_tag="ACIZE9_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGC6092069.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(34712..35953)
                     /locus_tag="ACIZE9_000169"
     CDS             complement(34712..35953)
                     /locus_tag="ACIZE9_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGC6092070.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(36193..36771)
                     /gene="pgsA"
                     /locus_tag="ACIZE9_000170"
     CDS             complement(36193..36771)
                     /gene="pgsA"
                     /locus_tag="ACIZE9_000170"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGC6092071.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(36980..37903)
                     /locus_tag="ACIZE9_000171"
     CDS             complement(36980..37903)
                     /locus_tag="ACIZE9_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HGC6092072.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(38642..39928)
                     /locus_tag="ACIZE9_000172"
     CDS             complement(38642..39928)
                     /locus_tag="ACIZE9_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGC6092073.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(39921..41189)
                     /locus_tag="ACIZE9_000173"
     CDS             complement(39921..41189)
                     /locus_tag="ACIZE9_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGC6092074.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            41441..41902
                     /gene="mscL"
                     /locus_tag="ACIZE9_000174"
     CDS             41441..41902
                     /gene="mscL"
                     /locus_tag="ACIZE9_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGC6092075.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(41961..42406)
                     /locus_tag="ACIZE9_000175"
                     /pseudo
     CDS             complement(41961..42406)
                     /locus_tag="ACIZE9_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(42499..42744)
                     /locus_tag="ACIZE9_000176"
     CDS             complement(42499..42744)
                     /locus_tag="ACIZE9_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGC6092076.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(42859..43437)
                     /locus_tag="ACIZE9_000177"
     CDS             complement(42859..43437)
                     /locus_tag="ACIZE9_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGC6092077.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(43514..44044)
                     /locus_tag="ACIZE9_000178"
     CDS             complement(43514..44044)
                     /locus_tag="ACIZE9_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HGC6092078.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(44048..44908)
                     /gene="rlmB"
                     /locus_tag="ACIZE9_000179"
     CDS             complement(44048..44908)
                     /gene="rlmB"
                     /locus_tag="ACIZE9_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGC6092079.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(44901..45296)
                     /locus_tag="ACIZE9_000180"
     CDS             complement(44901..45296)
                     /locus_tag="ACIZE9_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGC6092080.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(45293..46705)
                     /gene="cysS"
                     /locus_tag="ACIZE9_000181"
     CDS             complement(45293..46705)
                     /gene="cysS"
                     /locus_tag="ACIZE9_000181"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGC6092081.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(46702..47238)
                     /gene="epsC"
                     /locus_tag="ACIZE9_000182"
     CDS             complement(46702..47238)
                     /gene="epsC"
                     /locus_tag="ACIZE9_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HGC6092082.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(47324..47563)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(47560..49020)
                     /gene="gltX"
                     /locus_tag="ACIZE9_000183"
     CDS             complement(47560..49020)
                     /gene="gltX"
                     /locus_tag="ACIZE9_000183"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGC6092083.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(49190..50347)
                     /locus_tag="ACIZE9_000184"
     CDS             complement(49190..50347)
                     /locus_tag="ACIZE9_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HGC6092084.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(50381..51751)
                     /gene="radA"
                     /locus_tag="ACIZE9_000185"
     CDS             complement(50381..51751)
                     /gene="radA"
                     /locus_tag="ACIZE9_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGC6092085.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(51814..52341)
                     /locus_tag="ACIZE9_000186"
     CDS             complement(51814..52341)
                     /locus_tag="ACIZE9_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGC6092086.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            52571..53377
                     /gene="proB"
                     /locus_tag="ACIZE9_000187"
     CDS             52571..53377
                     /gene="proB"
                     /locus_tag="ACIZE9_000187"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGC6092087.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            53374..54621
                     /locus_tag="ACIZE9_000188"
     CDS             53374..54621
                     /locus_tag="ACIZE9_000188"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGC6092088.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            54697..55041
                     /locus_tag="ACIZE9_000189"
     CDS             54697..55041
                     /locus_tag="ACIZE9_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092089.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(55158..55484)
                     /locus_tag="ACIZE9_000190"
     CDS             complement(55158..55484)
                     /locus_tag="ACIZE9_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092090.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(56099..57301)
                     /locus_tag="ACIZE9_000191"
     CDS             complement(56099..57301)
                     /locus_tag="ACIZE9_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6092091.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            57418..57933
                     /locus_tag="ACIZE9_000192"
     CDS             57418..57933
                     /locus_tag="ACIZE9_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC6092092.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(58132..58578)
                     /locus_tag="ACIZE9_000193"
     CDS             complement(58132..58578)
                     /locus_tag="ACIZE9_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HGC6092093.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(58625..60103)
                     /gene="msr(C)"
                     /locus_tag="ACIZE9_000194"
     CDS             complement(58625..60103)
                     /gene="msr(C)"
                     /locus_tag="ACIZE9_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HGC6092094.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(60457..61086)
                     /locus_tag="ACIZE9_000195"
     CDS             complement(60457..61086)
                     /locus_tag="ACIZE9_000195"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGC6092095.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(61070..61534)
                     /locus_tag="ACIZE9_000196"
     CDS             complement(61070..61534)
                     /locus_tag="ACIZE9_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC6092096.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(62021..63289)
                     /locus_tag="ACIZE9_000197"
     CDS             complement(62021..63289)
                     /locus_tag="ACIZE9_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HGC6092097.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(63520..64257)
                     /locus_tag="ACIZE9_000198"
     CDS             complement(63520..64257)
                     /locus_tag="ACIZE9_000198"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC6092098.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(64324..64893)
                     /locus_tag="ACIZE9_000199"
     CDS             complement(64324..64893)
                     /locus_tag="ACIZE9_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HGC6092099.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            65021..65893
                     /locus_tag="ACIZE9_000200"
     CDS             65021..65893
                     /locus_tag="ACIZE9_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC6092100.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            66235..67107
                     /locus_tag="ACIZE9_000201"
     CDS             66235..67107
                     /locus_tag="ACIZE9_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGC6092101.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            67104..69062
                     /gene="nagE"
                     /locus_tag="ACIZE9_000202"
     CDS             67104..69062
                     /gene="nagE"
                     /locus_tag="ACIZE9_000202"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HGC6092102.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(69394..70245)
                     /locus_tag="ACIZE9_000203"
     CDS             complement(69394..70245)
                     /locus_tag="ACIZE9_000203"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC6092103.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            70368..70835
                     /locus_tag="ACIZE9_000204"
     CDS             70368..70835
                     /locus_tag="ACIZE9_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGC6092104.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(71098..71580)
                     /locus_tag="ACIZE9_000205"
     CDS             complement(71098..71580)
                     /locus_tag="ACIZE9_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGC6092105.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(71680..72543)
                     /locus_tag="ACIZE9_000206"
     CDS             complement(71680..72543)
                     /locus_tag="ACIZE9_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGC6092106.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            73141..74016
                     /locus_tag="ACIZE9_000207"
     CDS             73141..74016
                     /locus_tag="ACIZE9_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HGC6092107.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(74161..74313)
                     /locus_tag="ACIZE9_000208"
                     /pseudo
     CDS             complement(74161..74313)
                     /locus_tag="ACIZE9_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(74581..75912)
                     /locus_tag="ACIZE9_000209"
     CDS             complement(74581..75912)
                     /locus_tag="ACIZE9_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC6092108.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(76061..76774)
                     /locus_tag="ACIZE9_000210"
     CDS             complement(76061..76774)
                     /locus_tag="ACIZE9_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6092109.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            76949..78373
                     /locus_tag="ACIZE9_000211"
     CDS             76949..78373
                     /locus_tag="ACIZE9_000211"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6092110.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            78672..79379
                     /locus_tag="ACIZE9_000212"
     CDS             78672..79379
                     /locus_tag="ACIZE9_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGC6092111.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            79366..79689
                     /locus_tag="ACIZE9_000213"
     CDS             79366..79689
                     /locus_tag="ACIZE9_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGC6092112.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(79778..80815)
                     /locus_tag="ACIZE9_000214"
     CDS             complement(79778..80815)
                     /locus_tag="ACIZE9_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HGC6092113.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(81136..82119)
                     /locus_tag="ACIZE9_000215"
     CDS             complement(81136..82119)
                     /locus_tag="ACIZE9_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HGC6092114.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(82534..83304)
                     /locus_tag="ACIZE9_000216"
     CDS             complement(82534..83304)
                     /locus_tag="ACIZE9_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092115.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(83297..84232)
                     /locus_tag="ACIZE9_000217"
     CDS             complement(83297..84232)
                     /locus_tag="ACIZE9_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092116.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(84548..86197)
                     /locus_tag="ACIZE9_000218"
     CDS             complement(84548..86197)
                     /locus_tag="ACIZE9_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGC6092117.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(86314..88917)
                     /locus_tag="ACIZE9_000219"
     CDS             complement(86314..88917)
                     /locus_tag="ACIZE9_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGC6092118.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(88929..89978)
                     /locus_tag="ACIZE9_000220"
     CDS             complement(88929..89978)
                     /locus_tag="ACIZE9_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HGC6092119.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(90004..90318)
                     /locus_tag="ACIZE9_000221"
     CDS             complement(90004..90318)
                     /locus_tag="ACIZE9_000221"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HGC6092120.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(90334..90780)
                     /locus_tag="ACIZE9_000222"
     CDS             complement(90334..90780)
                     /locus_tag="ACIZE9_000222"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HGC6092121.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(90781..92703)
                     /locus_tag="ACIZE9_000223"
     CDS             complement(90781..92703)
                     /locus_tag="ACIZE9_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC6092122.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(92915..93811)
                     /locus_tag="ACIZE9_000224"
     CDS             complement(92915..93811)
                     /locus_tag="ACIZE9_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC6092123.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(93804..94484)
                     /locus_tag="ACIZE9_000225"
     CDS             complement(93804..94484)
                     /locus_tag="ACIZE9_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6092124.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(94485..95267)
                     /locus_tag="ACIZE9_000226"
     CDS             complement(94485..95267)
                     /locus_tag="ACIZE9_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGC6092125.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(95260..96177)
                     /locus_tag="ACIZE9_000227"
     CDS             complement(95260..96177)
                     /locus_tag="ACIZE9_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGC6092126.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(96341..96595)
                     /locus_tag="ACIZE9_000228"
     CDS             complement(96341..96595)
                     /locus_tag="ACIZE9_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092127.1"
                     /translation="MSTITTITMVASPLGLALFGALFDWKTTQPRLRDSLIFLGGSLA
                     IVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEKKESGN"
     gene            97452..100679
                     /gene="fss3"
                     /locus_tag="ACIZE9_000229"
     CDS             97452..100679
                     /gene="fss3"
                     /locus_tag="ACIZE9_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HGC6092128.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            100792..101106
                     /locus_tag="ACIZE9_000230"
     CDS             100792..101106
                     /locus_tag="ACIZE9_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGC6092129.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            101119..101493
                     /locus_tag="ACIZE9_000231"
     CDS             101119..101493
                     /locus_tag="ACIZE9_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGC6092130.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            101503..101838
                     /locus_tag="ACIZE9_000232"
     CDS             101503..101838
                     /locus_tag="ACIZE9_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HGC6092131.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            101921..103261
                     /locus_tag="ACIZE9_000233"
     CDS             101921..103261
                     /locus_tag="ACIZE9_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGC6092132.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            103339..104013
                     /locus_tag="ACIZE9_000234"
     CDS             103339..104013
                     /locus_tag="ACIZE9_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HGC6092133.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            104006..104170
                     /locus_tag="ACIZE9_000235"
     CDS             104006..104170
                     /locus_tag="ACIZE9_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092134.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            104246..105388
                     /gene="dcm"
                     /locus_tag="ACIZE9_000236"
                     /pseudo
     CDS             104246..105388
                     /gene="dcm"
                     /locus_tag="ACIZE9_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            105378..105668
                     /locus_tag="ACIZE9_000237"
     CDS             105378..105668
                     /locus_tag="ACIZE9_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092135.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            105927..107111
                     /gene="mobT"
                     /locus_tag="ACIZE9_000238"
     CDS             105927..107111
                     /gene="mobT"
                     /locus_tag="ACIZE9_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HGC6092136.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            107108..107245
                     /locus_tag="ACIZE9_000239"
     CDS             107108..107245
                     /locus_tag="ACIZE9_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HGC6092137.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
BASE COUNT        31100 a        22242 c        19347 g        34580 t
ORIGIN      
        1 tcattcttac atgctgacag caaagtcagg ggcaaaccat tgaactgaac caacttttac
       61 gctttcgcct ggttgaggag catggatata ttgtcctccg cctaaagcaa tcgctacgtg
      121 gtaagttccg ccttgtgacc cccagaataa caagtctcca gcttttgctt gagaaactga
      181 aatttttgtt ccagctgatt cttgaggaac tgtccaacca ccgatgtcac gaccagttac
      241 ttgcatgtaa acatagcgtg tgaaccctga gcagtcaaag ccacttggat ctttaccgcc
      301 ccaaacatat ggagtaccaa tatatttgta agcttctgct acgattgctg caccattcac
      361 acttccagaa ggagctggag caggtgttac aggttttggt tgttcaggtg ttggtgttgg
      421 cgttggagcc ggagtactac ttcctgtgcc gtttcctgta tcaacacttt gatctgttga
      481 tggtgttgta ggcgcaggtg ttgttgattc ttctgttgtt gaagattcag gcactgttgt
      541 tgattcttct gttgctgaag attcaggcac tgttgttgat tcttctgttg ctgaagattc
      601 aggcgctgtt gttgattctt ctgttgctga agattcaggc gctgttgatt cttctgttga
      661 agattcaggt gttgttgatt cttctgttgc tgaagattgt gtagctgatg atgattcttc
      721 agtcattgaa gattgtgtag ctgatgattc ttctgttgct gagctttgtg cagtagatga
      781 agcttgagta gcttgtgctt cagcctctgc ttgttcgcgt gcttcttttt cagctttttc
      841 ttgtgcagct tgttgacgag cttgttctgc tagacgttgt tgttcacgaa tacgagcttg
      901 ctctgcttca gcttctgctt tttgacggtt caagtcagct ttcttgtctt cagcagttgc
      961 ttgttcagca gctaatgaag ttttcagtac gttcaaatca gcttgtttag ataaaagatc
     1021 gcctttttga gattccaaag cagcttggtt ttcagctaat tcttttagtt tagcatcgtt
     1081 ttcagctttt ttgtcttcta cagctttttt atcttgtttt tgttgttcca tcaagtcgtt
     1141 gtttgctttt accatcgttg tcattgcttg aacgcgtcca atagcatctg ctaatgaatc
     1201 agcattcaat acagcatcga tgtagtttga gcttgtgttg cttacttgtg cttcgcgtgc
     1261 ttgtttttgg attgtatctt cacgtttttc aatacgttct tgtaaatctg caatgtcttt
     1321 tactaattgt gcagattctt gacgcaatgt atcttgtttt gctaataggt cttgtgcttg
     1381 tgtgttgatt tcagaaactt ggctttctaa ggcatcgatt tgtgattgtg catctgcttg
     1441 ttgatttttc aagtctgcaa tcttttgatc ttgctgttgt atctgagaat caaaatcgtc
     1501 cgccgcggca gcgatcggtg atgctacggc agtcaaggtc attgaacata ccattactgc
     1561 tgatattaaa ctctttttca ctcttcattc ctccgactgg cttaatttaa taaatatcta
     1621 aatatattta agtctttctt aacgatataa aaattgtacc atagcagtgt gtcaacgata
     1681 taatagttat gttacaaaaa tgtttcaaaa caacttttaa aaatgacaaa actgttcgtt
     1741 tcagaaaatg atcatgaaaa agccgcgtta agtctagcat ttcttaagat aacaacgatt
     1801 ctttttcgct ttcgacctaa aaataaaaaa agaaattatt catcactgaa taatttctta
     1861 aagggaaaaa tgaataatac aaatataatc atgttcaaca gcagtgtagg tcctaaaaac
     1921 cttgtaataa aatacgtgtt atttactact gctaatttaa aaatcaactg gaccaccatc
     1981 gtaaacaatt cataacccgt gacaaagatg atcatactga aaaattcagt aaagatgttg
     2041 acatggataa cgtctttcat tacatacatc aaccatacaa ttaaagggag agctactgca
     2101 tagataccga taacgccaat atagtaagcg tcatagatag ccccgagaac aatcgtggta
     2161 atcagtaaat aacgtttttc aaacgccata ctgcaacata ataatgccaa tatcagaaag
     2221 tgggcatttg acatataggt gcctttcgac cactccccta gcattcttgt taaatgacca
     2281 tctatcaaca tcaaaaagaa caaaacgatt ggcagatagt acttcattgt ttctttcttc
     2341 aacatggact aatcctccgc tagccgttgg acaatcgtca caactgacac gtcatacatt
     2401 tctgcataag gtttcacata aacttcccga tccagcccat aactatctgg tttcgtttta
     2461 ataaccgtac cgatcggcaa gttagctgga gaattccctc caagaccgga tgtctggaca
     2521 acatcccctt ctttgatatc cgtatcacca gttaattggg tcaccactaa ggcatggagc
     2581 ttttcatcat agtttttaag caaaccaaac gcttcgccat tagccgaaga tacccgtact
     2641 ggaaaatgat tggagctttc attagaggat gacagtaatt cgattttaga cgaagccgta
     2701 ttgacctcga tcactcggcc aatcaatcct ttttgcgaca tgactgccat atttgcttcg
     2761 ataccgtctt tagaaccctt gtctacgatc agcatgtcct gccaactgtc aggcgaacga
     2821 gtaatgacat ttgccgttac tttttcgtaa ctagtcagcg tctgattcaa ctcaagttct
     2881 tttttcaacg cttcgatttc tctctcgtaa ttcttgtttt gctgtgaaac gtcatcatag
     2941 ctatcgattt tttcttttag ccgctcattt tcggcataag ttgaaaaaag attatggaca
     3001 gaatctactc catttcgtac ccaccgtact ggggcagaga ttgttttatc aaccattgca
     3061 acactgtcat taacgatgga ttggaagaaa ttgggctttc cttcattcgc tcgctgcgca
     3121 gcggtcacac ttagtatcgt caccacgatg ataacaataa ccaaggtaat aataatattt
     3181 ttattaggat tgaacttctt cacaaagaca cctcgaatta attagactct tgtgttcaat
     3241 tttatcacta aatgccgtga aacaaaaggt aagttgctcc tcttaagctt ttttttagca
     3301 aataatagat tctgtcattt ttagcctgaa agacaaattt ttttatttgt ttatggatca
     3361 atctttgctt tgaataactg caatcatacc atctgaaaaa gaaaattctg cggtatctga
     3421 aagaaattcg ttacttgcat aagatgtcgg atattctact tctttatttt ccaatacata
     3481 cttgctgcct tttaatgtaa gattcgagac gggagtcaag cagcaataag ctaaatactt
     3541 catatctggt atctgtctta ctatatgctc tccaggcaaa taataagaca aataattttg
     3601 acaatctctg ataataagct gatgggcaaa gggtttgaag cgaggttcca tacctaacca
     3661 gagattggct aaaagatgat ccaatcttcc gcccgtagct ccaatcaaag tgacttccgc
     3721 ttgcgggtaa cgttcaaatg tttttaagat acctaactgt gtatctgtat cgtctttttc
     3781 tgcaggggaa cgggtatact ctttggcttt tgcaaatact tccttctgct cttcgttcga
     3841 caatgaatca aaatcaccca ctgccagatc tactgggtag cctgcttgaa gcaggtacag
     3901 cgcaccacgg tctatcccga cataggcatc gtatttggac agcagagact gcggccagtt
     3961 ttgcggatta cctccagcag ctaataaaat tttcatttag tctaatgcct cttttaatcg
     4021 ttcgatttgt ccgactggat tttcggctcc atagatatat gatcctgcaa cgaagacatc
     4081 cgcccctgca tctttacaga tttttgctgt ttctggaacg attccgccat ctacttcgat
     4141 tgcataagtc caattgttct ctctacgtag atcagcgagt tccgtaattt tttctactgt
     4201 ttcttcaata aagctttgtc cgccgaaccc aggattgaca gtcatgacta gtacttgatc
     4261 agccaaaggc aaaacatgtt tgatcatgga gactggtgtt cctggattga taactactcc
     4321 agctttaact cctaagcttt ttgtcatttg aagtgcccga tgaatatgag gagttgcttc
     4381 gacgtggaca gtaatgatat ctgctccagc ttttgcaaat gctggaatgt agttttctgg
     4441 atcaacgatc atcagatgga cgtctaacgg taatttagta acaggacgga ttgcctgaac
     4501 aatatttggc cctaatgtga tatttgggac aaatcggcca tccattacat ctacgtggat
     4561 gtaatctgcg cctccttttt ccactaactc aatgtctctt tgtaaattgg caaaatctgc
     4621 actcaaaatg gatggtgcta tcttcattct tgtttcctcc tattttcgtt taccttcttt
     4681 ttttgcatac attggttttc ttttttcgat ttcttgtaag aattgcaaat aattgtcgta
     4741 acgtgtctgt gcgataccac ctgtttctac tctatgtttt acttcgcagc caggttcttt
     4801 agcatgcatg cactctctaa atttgcaatg gacagaagct tctacaaatt caggaaattg
     4861 tctcggcagt tctcctgctt caattgtcaa aaagtcaatc gagctaaatc ctggtgtatc
     4921 tgctactaac ccgccataga taggaatcag ttccacatga cgtgttgtat gccgtcctct
     4981 tccaagtgca tcagaaatct ctcctgttgc taaattcagt tccggtgata tttgattcag
     5041 tagcgtcgat tttcctgctc cagactgacc cataaagacc gatagccgtt ctgggaagta
     5101 acggatcagt tctgtcgtat cacccgtatg attgggtaca atcaccggat agcctatttt
     5161 agtataggtt tgcttgatct cttcgatttt ttctgggtcg tctgacaagt cggtctttgt
     5221 caaaaaaata atcggttcga tcgactcgta ttccaaggta actagaaagc ggtcaagtag
     5281 attataagaa aatgcaggct ctacgatact tgtgacaatg attccaagat caacatttgt
     5341 gactggtggg cgaactaatt gattttttct cggcaagatt tccagaagat agccgtctgt
     5401 ttgattttca ctctcaaaga tcacctgatc tccgacaagc ggcgtgattt tccgattccg
     5461 gaaatttcct cttcctcttg tttgataggt ctctccgttt gcgtatacat agtaaaaacc
     5521 gctgattgct tttctgattt gtcctttgat aagtgccacc tccgtttttg tttattttac
     5581 catacgaaga ggaaagtagg tgttattcca tgcaaacttc tcaaagtata tggcttgaaa
     5641 attgatcaaa agagatagaa acacaaaaaa gagaatgcaa caaatcaatg tcgcattccc
     5701 ttctgatata ttttattcag cacttatttt gaactttctg aggtgctagc tgatgaactt
     5761 gtggagctgg aagattcttc ttttgaagag ttgcttgtgc tactggagct acttgagctg
     5821 ctagaactgt ctgaagagtc tttttcagaa ctagaagacg ctggatctgg tcctttagag
     5881 taaattacgt tcacaaccat tcctttggta attgtcgttc ctgcccctgg tactgtacga
     5941 atcactttat ctttatccac cgtgtttgaa tattcggaag tctcatgccc gatatattct
     6001 gcaccgacac tagctaaata actttgtgct tcgctttttg tatagccgga gatatcattc
     6061 aatttaggct ctgttccttg gcttacgaca aaattgatgt aagtttcttc tgctacaact
     6121 tcacccgagg ctggatcctg actgatgatc gaacctgatg gtacagtgtc gctatagtca
     6181 taagtagcac taatattatt gatattgaat ccttgtgtaa caagccaatt acgaacagtt
     6241 tcgtagtttt ctcctacatg actactcaaa gtcactgttt ctggtccttt gctgactgtg
     6301 aaagtaatcg tgtctgtttt aggatcgact tctgtatctt ctgatggaga ttgcgaaatg
     6361 atcattccgc tttctacctc tgaactgaat tcctcttctt tttgaatcaa gtcagcagaa
     6421 aaccctaatt ctttcaaact tgcttcggca tcttcataac ttttaccact gtaatcatct
     6481 aatttgattt ttttcgtgcc gctactaata tacagagtga cttcgcgttt ttgcttgact
     6541 gtcgttcccg ctgccgggtc tgtcttcact acattacctt cttcgatttt gtcatctgca
     6601 atttcttctg tttttgttgc tacttctaat ttcgcttttg cgagtgtttc tctagcagaa
     6661 gcttcagaaa gatcagaaac atcaggaaca acaacttctc ctcgcccgcc agaagcaaag
     6721 aatacagctg ttccgattcc taaaacagca agaatagcta ataggatcag ccaccatttt
     6781 ttctgtcctt tctttttagg atcaggcaga acttcttcct cctctggtaa ggtttcgttt
     6841 tctggcttgt cttttggcag aggcatagat ttgaatgaat caggcattgg tgcatcttcc
     6901 gtaaggggtg tgataacttt tgtttcatta tccatcacat gaggctgcca tttttcttcg
     6961 tttgcacgag ctggtgataa tactgtagaa agatcatcag acatttcctc ggctgactta
     7021 taacggtctg caggttcttt agccgttgcc cgtaaaatca cgttttccag tgcttgtggc
     7081 acatttggat caagtgcttt tatagatgga agatcatctt gaaaatgttt taaagcaatt
     7141 gttacagcag attcaccatc aaacggtacg ctacccgtca acatctcata aaggatgatc
     7201 cctaaagcat aaatatctga ctgcttcgtt gccatacttc ctctggcctg ctcaggggac
     7261 agataatgaa cagatcctag catcgtattc gtctgcgtga tcgatgtttc agataaagcg
     7321 atagcaatcc cgaaatccgt gatttttaca acaccttcat tatcgatcag tacgttttgg
     7381 ggtttcaaat ctcggtggat gatttgatgg ttatgagcta aagaaatagc agaaaggatc
     7441 tgctgcataa tatttactgc tgtttcataa ggaacaggat aatgtgtttg gatatatcgt
     7501 ttcaagtcca ttcctttgac gtattccatc accagatact gcatgttgtc ttcttcacca
     7561 acatcgtaaa cactaacaat gtttggatga acgagttctg ttgctgctaa agcttctctc
     7621 tgaaatcgtc gaatcgcagt ctggtcattt tgaaagtcaa atcgtaagac tttaactgct
     7681 acatcacgat ccaagattaa atcgtgcgcc aaaaatacat ttgccatacc accgctaccg
     7741 atatttccag tgatttgata acggccattt aattttttgc ccaactcgat catacactgt
     7801 cctccttata ttcgataaga agaacggtga tattatccgc tccgcctgct tcattggcac
     7861 gatcaatcag ctcagttact ttatgagaca atgggccttc ttgattgatg atcgttccta
     7921 tttcttcttc agacagcatg ttcgtcaagc catctgaaca taacagcagt cgatctttta
     7981 gttgccaaag atgagtagaa acatctactt cgactgttcc aggcatgccg acagaacgtg
     8041 ttaaaatatt tttccttgga tggttcactg ccatttcttc gctgatttct cctgatttga
     8101 ctagttcatt gactaaagaa tgatcctccg tcaattgcat gattttatct tcacgaatca
     8161 aataagctct gctatcccca acattggcaa tcgtgaacca gtcatctgac agagcggccg
     8221 ctacgattgt tgttcccata ccgttatatt ccggctgttc ttgtccacgc tgataaatca
     8281 gcatattttc ttcttgaatc gattgaatga accattgggc gattttttca tcgtcaacag
     8341 cttcttgttt ttcccaagct tcgcctagat tcgttaccgc catctgactg gcaatgtctc
     8401 cggcacgatg accacccatc ccgtctgcta atacagcaag cttgagacct gaacggctgg
     8461 taaatacact ggcatagtct tgatttgtgt tacgtcgtct tcctacatct gattgatatt
     8521 caatctgcat tttttcacct cattactttt tgcgcaaaca acaaatgaaa aatccatctg
     8581 tgtaaaactg atgcggatac aaagtcaaca ttttctcttc gattgatgat tgtagcatag
     8641 gattggtcaa aacatcaatc ctctcaaaat cagggtgtct ttccaagaaa gcagaaacaa
     8701 cgtcttggtt ttcttctttt aagatcgtac aagtgctata agtcagaata ccggaagact
     8761 ttaaagttgg tgcgcagctt tctaaaattt ccaattggat ttttggtaaa ttcgctaatt
     8821 catccggctg ttttttataa cgaatatctg gttttcgccg aagcagccca agacctgaac
     8881 aaggcgcgtc tactaaaatc cgatcaaact gctctgcttc gaactgttta ctgacttctc
     8941 tagcatccat cttttgagcg tagacagcag aagagacacc tagacgtgct gcattatctt
     9001 caatgagttt gactttgtgt tcgtgtacat ctaaagcgac cacttctcca ccgcatgacg
     9061 gatctaaaaa agaagcaata tgcgtcgtct tacctccggg tgctgcacag gcatctaaga
     9121 catgatgttc aggctcgatt tgcatagacg gcgctacaag catcgaactt tcatcttgga
     9181 tcgtcatgac gccatcgtgg aacaatgagc tagaagctaa atgccctttt ttcgctacta
     9241 taccgtatgg actgacttgg cttttttcag ctgtgatctc ttcttcttgc aaaacagtga
     9301 tggcctgatc tctggaaagt cggcgtgtat ctactcgggc actagcatgg ctaggctgat
     9361 atagcgataa accgagcttt tcagtttctt cgtatccgat ttgatccacc agtcgtttcg
     9421 tcatccatag aggcaggctg attttgacag aaagtctttc gataggatca gcaatgcctt
     9481 gcagatctgg tgctccttga cgctgataat tcctcaagac accatttaca aatttccctg
     9541 tcccaggatt tccttttact tttgcgattt cgaccgcctc gtttaaaata gcatgtgcag
     9601 ggactttatc taaaaattct aattggtata cagaaagata aagaagcatc ttgacccagt
     9661 catccacttt ttttgcttta gcgatcaatg gtgcaacgta aaattccaat agtcgctgat
     9721 ggctaatcgt accatagatc aattctgtaa ataaacccac atctttttga tttagctcgc
     9781 tttgtttgat catctcattc aacaaaagat tcgagtaggc gccacccttg ttcactcgct
     9841 ctaatgtcag taatgccata tatcgtactg attttttcat ttttttaggg atttttttca
     9901 ttatttcacc tgctgaccaa tctgaacttg ctgaccgctt ccgttaagga aatcatgtac
     9961 ggcctgtttt cctttaccag ctggctgtaa ttcattgatg gctaagacgg tctgtttacc
    10021 gcaagcaatc catagatttt ttttgtcttt ccggatgatc gtaccaggtg ctttgtctgt
    10081 agtttctgcc aatacttcaa ccgataataa tttccagcgt atgccctcat aggtcgtgaa
    10141 tgcaattggc caaggacgca ttccgcgtac ttggttgtca atttcttctg cagttttatg
    10201 ccaatcgatt gcttcttgtt cccgtgtgat gtttggcgaa aaagttgctt ctgactcgtc
    10261 ttgaggtact ggtttttgtc catccaaaat attgggcaat gtttctagca atagctttct
    10321 tcctaaaagg ctaagctttt caaacatcgt ccctacatca tcttgtttag tgattggtat
    10381 gctttcttgc gcatagattc cgcctgcatc catttttttg atcatttcca tgatcgttac
    10441 accagtttct ttctccccat tcatgatggc ataatgaaca ggcgcacctc cccgatattt
    10501 aggaagtaaa gaagcatgga cattgattgc ccctaatttt ggtacttgca ataacttttc
    10561 aggcaagaat tggccaaatg ccgcagtgac gatcacatca ggcaccaatt caatgatttc
    10621 ttccatttct ggcgaaccgg agattttctc tggctgcagc acacggatac cgtgcttcag
    10681 agccgctttt tttaccggtg tcggcgtaat tactcgtttc cgcccaactg gacggtcggg
    10741 ctgtgttacc actgcctgga tctcgtaacc tgattctatc agcccttcaa gaatcggcac
    10801 agaaaaagca ggtgtgccca taaatactag cttagtcatc aagatgttcc tccatatatt
    10861 cttcaagttc ttcttccggg atctgctgta tcattttctc aatgaacaag ataccgtcta
    10921 agtgatcgat ttcatgctgg aaggcacggg ctaaatagcc aaaagccgtc acttctatct
    10981 cttctccgtc tcgatcataa taacgcacgg tcacttcatc tgctcgcttg accgttccat
    11041 agacatgcgg aatactgaga caaccttcta cgtcaaggct ttcacctttt gcttcgatga
    11101 tttctgggtt aatcagttca aatttctcgc cttcatctac ttcgatcaca gcaattctct
    11161 tgttttgtcc tacttgagga gcagcgatcc ctattccgtc attcgcaatc attgtctcat
    11221 ataaattgtc taataaagcg attgtctcgt ccgtgattac atcgattggc tgagcagttc
    11281 tttttaattt atcattaggg tggatcaata taggatagcg cataatttgg ccctttctta
    11341 aataaagttt aatggttcgt tgtcaattgc cacaaaaaga ccttgtcgct gttctttctg
    11401 gcttccattc aaaatttcat ccaaaacatg aggaagattc ggttcatgtt tatatttgat
    11461 gattagttga taataatatc ggtttttcac tctcaaaatc atgctgggcg ttggccctaa
    11521 tagcaagctt tgagggctta acacttcttt tagctgattg gcaatctgaa agattttctt
    11581 tgccgctact tgttcttcag gatggctggc ggttattttc acagtaaagt aataaggagg
    11641 atagcctcca cgatgccgta catgcatttc ctgctgataa aactgctcat aattttgttt
    11701 tttagccaat tctatggcgt aatgttgagg attgaatgtt tggatcacga cttcgcctgc
    11761 tttttccgct cgccctgctc gtcctgaaac ttgggtaagc aattggaatg tatgctcact
    11821 agaacgaaaa tccggtaaat tcagggaggt atcagcattc aacaccccaa ctaatgtcac
    11881 ttctggaaag tccaaacctt tagcaatcat ttgtgtccct aataatatat ctgcttcttt
    11941 tgcaccgaat ttttgtaaaa tctgttcgtg tgcccctttt cttcgagtgg tatctacatc
    12001 catacgcaaa atcctagctt gcggataaag ttctcggagt tcctcttcta ctttttgagt
    12061 acctgttcca tagtagcgga ttttattgcc gccacaatta ggacagcgat tgggaatagg
    12121 ttcttcatgt ccgcaataat ggcagcgcat tgaacgtgta tccatatgca gtgtaagaga
    12181 gatatcgcaa ttaggacatg gaagaacaaa tccacagtcc ctacacatca caaaagacga
    12241 atatcctcga cgattgagca gtaggacagt ttgttctttt ttgtctaatc gattttgtat
    12301 tttttcctgc aaattagcag aaaaagtaga ggtccgatga ttctgaaact cttcacgcat
    12361 atctacgatc tcaatagctg gaagctgtgc agctgctttg gctcggtggt ttaactgcaa
    12421 taactgataa acgccttttt gagctcgtgc tcttgattct aaagagggcg tcgcgcttcc
    12481 tagaactatt gggcaatgat gatatttact gcgccaaatt gctagatctc tcgcatgata
    12541 acgcggtgtc tcatcttgtt tgtaacttga ttcatgttct tcatcgataa tgatcagccc
    12601 gatatttttc agcggggcaa aaatagcaga tcgtgcgcct actactactt gcgcttcttc
    12661 ccgctcaatc ttgcgccatt catcatattt ttcaccttgg gaaagtccgc tatgtaagac
    12721 cgcaactgat tctccgaagc gtcctttgaa tcgctcgacc atttgcggag tcaatgcgat
    12781 ttcaggcact aacataatag ccgttttatt ttctgacaaa acatcagcga ttgcctgaag
    12841 atatacttct gttttcccgc tgccagtgat tccctccagc aaaaagacct gatctttttg
    12901 ctgctgacct gctgtgatga tttgttcgac agcatttttt tgttctgcat tcagttccaa
    12961 tgccgtcgtt tggtcaaata ctcggtcttt ataagggtcg cgataacgtt ctgattctat
    13021 aaactccagc cagccctttt cttttccttg attcaagaca gcagtactga ttcctttatt
    13081 tttgaaataa gcaattggtt cttcttggct cagttcagat aaacacaaaa gaagttcttt
    13141 ttgtttcttg gcattttgcc gtaattttgc ccattcttct tcgatttgct tttcagttaa
    13201 caaagaacgg accaaacgaa tcgtttttac tttatttcgt gtatggactt catatttgat
    13261 atctactaat tgctcttggc gccagcgaat caattgagaa aggctgcctt cttcttctgc
    13321 ttccttccag gaaatcactt ctcgctgatc aaacaatacc tgaacttctg gtgtgtctgc
    13381 caaaggatag atcaatttat catattctgc tttcatcaca ctcggaagca tcgtttgtag
    13441 acaagtgatt ttgaatgcgt aagtaatttt tttcatataa tcagctaatg aaagtaattc
    13501 ttcattgacc accggagcaa ggtctagcaa acgaataact gccttcaaag atggattagc
    13561 tgattcttct gatttttgga tagccataac aaatccttgg acatgacgat tgccattacc
    13621 aaaagggact tctactcgca tcccgacttg caaagctgtt tccatttcag agggaaccaa
    13681 ataagtgaat ggctgatcgg tctgcatagt aggtacgtcc acaatgactt cagctgttaa
    13741 tgtcatggtt cgtttcctcc tttttttgtc ttttcttatc aagcgacaaa aagttccttg
    13801 cctattttac tagagatcga tggatttgtc ttatcttctg ccaaatccta acaaaaaatt
    13861 aacagcagat aagaaaaaaa agaactgtgt caaaaagttc agacacagcc ttttctacca
    13921 gacaataagt ggcgaatgtt tgaaaaggaa acagctgggt ttgcttttct ttttagatgt
    13981 tcgctctatt tttctttatt acattttttg ctcttcacgg atacgtgatt ccaattcgtg
    14041 ttgttcacgc tctttttgtg cttgacgttc ctcttcttcc atcttcaaac gttcacgttt
    14101 taattcagga tgtggatcat tgactacatt tcctgcatcg atttcttcta aagcttgacc
    14161 gacgcttttt actgaatcaa aagaatctag agtaggctgt gcacttgcat ccaattcatg
    14221 cgcgcgttta cttgctaaaa tcactagaga atattttgaa tttacacgat ctaatagtga
    14281 gtcaattgaa ggttttaaca tcataagact acatctcctt taacatttta atatatttac
    14341 cgattacgcg atctactcga aaatgttcac tggcaataat gtttttgatt cgttcaactg
    14401 ctagcggcac ttcatcattt acaacagcat agtcgtaaag agccatcatt tcgatttctt
    14461 cttttgcaac tttcattcgt ttttcgatta cttcatctgc atctgttcct cggcctacga
    14521 tccgtgattt taattccgct aaatctggcg gagtcaaaaa gatgaataca ccatcgggca
    14581 ctttttcttt gacttgtttt gctccttgga cttcaatctc caagaaaaca tcttttcctt
    14641 catccaatgt cttgttgaca tatgacaaag gagttccata ataattcccg acatattctg
    14701 cgtattccag catctctcca gcttcgatca ttgattcaaa ctcttctttg cttcggaaga
    14761 aataatcaac gccttcgacc tccccttcac gcattttacg ggtagtcatt gagatcgaat
    14821 actgaaaatc attatcctca ctctcaaaaa ttgcttttcg tactgtgcct tttcctacac
    14881 cggatggacc agacaacacg attaataatc cacgctctga catgacgacg tcctttcaac
    14941 tagtcttttt gtacttatcg tttattttgc actttttttc tgcaactttc aaggttatct
    15001 ttaattatag ctagaaattg gtaaaaaagc taccctgtac caagaggtcg taaaaaagct
    15061 gtcctgcatc aagtaataag aacagccaaa cataaacagc ttctcatgtt tttcgtttgg
    15121 ttggggttat tatcgcagat gcaagctttt gaacgccgtg tataagaggt cgtgaagaag
    15181 ccgattagtt tcgagtatga agaaaaattt tgtgaaaata gtttctcaca tttttgcata
    15241 aatttggctt aataccgaga aaatggtttt tgaacatcac ttattcaaaa taaaaaaaga
    15301 ttgtgacacg aattttgtca caacctttaa atgtattcct agagcaaaga agctaagcga
    15361 agaaatccaa ttctgtttat ttattgtatt tctttgttca gcatccttgc taaaagccca
    15421 tattggacaa agtattcact acacccatga tctcatcttt tcgagaacgt gctttttctg
    15481 tcggatcttc tacctcttct gtgtcaattc gaacaataaa tttccgattc atcgtcacgt
    15541 aagcaccgtc gttgatcaaa ataaacagtt cgttctcatt atagtctgca caggcatctt
    15601 tccatacgtc aaagccgttt ttttcagaag ggatatcccg tttaaccaca gtttttccac
    15661 ttaattcgtg gaacgttacg tcataatatt tcattatctc tacctctttc gtcattcaat
    15721 attttgtact tgttctctga ttttttctaa gatcgtctta gactggacga cttgattttt
    15781 aatttcgatt gcatttgatt tggaaccgat cgtgttgatt tcccgattca tttcttggat
    15841 caggaaatct aattcccgac ctacaggaca ttgtgcttcg ataagttcat ctagtttttg
    15901 tacatggatc gccagacgat ccagttcctc gtgaatatct ccgcgttcca acaagatggc
    15961 tagctccgtc aacaaccgtt gctcatcgac tttcgctcca agaaattcct ccagcttttt
    16021 ttgatacctt atttgaaatt ccttttcata gatttctaca aaactatcga gtttttttag
    16081 tacttctttg aattcttcag tattcttttt caacactaaa gctaaagctt gaccttcttt
    16141 ttctcgactc gcctcaatag aatcaagtgc gcttttcaat gtatctagag ctaactgtgc
    16201 caattcttcc atgctctctt ccggtttttc ttctaccgtt acgaagtttt cgtccagcac
    16261 gaagcgttcc gccatccgac taattgacac ttgattttga ctaccgtatc gttgttgaat
    16321 tccgtctgtc aattgagtga taagtgaatc aatcaattcc cagttgatga cgatctgttt
    16381 ttcgtttttg ccaatataag ctagattcac aaatacttcg attcgaccgc ggcttaactg
    16441 ctgtttaata agctgacgaa aatcgttttc aacaaagttc aggattttag gacttcgtat
    16501 ttgaacatct agaaaacgct ggttgacact ttttatttca atatctaact gatacgcttt
    16561 tgtttcgcgg atggctttgc caaaaccagt catacttttc attcgacagg gtccttcctc
    16621 attacatatt ttctattgct ttttgcagtt gttcaaactc ttcgttcgtc aatgtcaggc
    16681 ctttccccat tttttcatgg tctggcgccc aatctcgaag atcgaatttt ggcgggcgac
    16741 cattccagct gactaggttc agttctttac gccacccctt gttgttttct gacaatatag
    16801 cgatttcttc tacgatttca tatgaaaatt cttgtgccat ggttgttcct ccttgagata
    16861 atataaatat aggatcagta atgtgtcaac tggttgctta agcaattcat gctgcaaacg
    16921 atccttgcgt tttccttgta gcagataatc aaaataaaca gttttcgtgc gctcattttg
    16981 tattttttgc tggtattttc gataccttcg ccattcttca gtacttaatt gaccaatttg
    17041 tgccaataaa tcatccggca tactttttat atcttgttgg cagatcattt gaatcatcat
    17101 gtctacttga tagatttcat tgggcagtaa aaaatgtttt tttgctaaaa gttctagcat
    17161 cgccaatccg catgtctctg gtacgaccct gttcttatat aaattacgca gtttttgcca
    17221 aaattttatg cttttgaaaa aagataattc taactgaatt tcttttgtta agtaagacaa
    17281 aaatcctcgc cagtatgttc ttgcaggttt aacagaatga aatgtatacc agttcccata
    17341 gtaatagcct aatcgttttt tcatttccag atagcctaat tgtaaattta attggttcct
    17401 ttggctatca aaaagcagaa agctgcctag tgtccacaat gtttgacatt tccaatggat
    17461 aaaaatgtct ggcatacgaa tttttttcgc tgggcctggc ccttgcacat ctacgacaaa
    17521 tgcctctgtt gctcctttgt taatcgcaat atcaataggt attttgttgc gatacccacc
    17581 gtctgcatat ttattttttc cgatctttcg ataagccata gcgggataaa atgaagcaga
    17641 ggcgagtatc caatctggta tttcttctgt ttttgtctgt tggatatcag tcactacttc
    17701 cgctagttct ggcagtttag tagacaccgt atataaacgt attttgggat tatgtttgag
    17761 taaggacaaa tccaaattgt ctttgaccat cttttccaat ggagcagaag aaaccccgcc
    17821 ttcaattagt gctgttttcg tcatttggcg tctttctcga tagaagcgtt cacgaaggtc
    17881 ttcaactgca gccatttctg gtaacgcaag cacttgtctt gtcgacagct ttttccataa
    17941 attcacagct tttttcatat ctccttgtaa aatcaatgcg ccgttcaacg cacctaccga
    18001 ggtacctgtg ataatctcaa agttgatatc atgttccttc agcgcctgcc acacaccaat
    18061 ctgataagca ccgtgcgctc ctcctccacc taaaacaagt gctgtatgat agaccagctt
    18121 tttatttaat tgtgtggttc cttgatagcc gtttttatga aaaatacgca accattcttc
    18181 tgatagagga gattgaaata aaaaacaaca gttttcttta ataaaaaaac gagcgcaagc
    18241 ttccatatac cgaaaaaatt ttttccattc aaaagtttca ccttcaatca acagattatt
    18301 aaaaataaca tctcctctac ttttagcaat agtaaaatag acggtatatt ttttcgatac
    18361 tgctttaaaa gcacattgct tttttgcaga acgccaaaaa gcgtctctac tttcttgatg
    18421 actttgaaaa aatggaaggg gttgttttgc ttgctggata ggcgaataca gcgacatttt
    18481 ctgtgaaaag taaacttttt ttatctccat cgcgctctcc tttttcttca agtataccag
    18541 tacgtcataa aaaggtcatg agtctcgtat tcgactttgt agattccata agaaaacaat
    18601 tcataaaacc tcctttaaat aaaaaaatac aaaaatcaca aaaattaatt gaaaatgaga
    18661 gtgttttcaa tgaaaacgtg attttgtaat ggaattttaa aataaaagaa acaagctttt
    18721 ttaatgcaaa tgttgtaaaa taaaagagat taagaggaaa taagaggagg aacatgatga
    18781 ctgagtcagt ttatgtacat attgatacca caagtaatgc tgttttaaca aaagggctga
    18841 ctgctactga ctttgcaaac agtatcgtgc attttcctca aaacttgctc ttgcttgatc
    18901 catctgcttc tgctggagaa tatgaatccc atacagggct gaaagtaatc cgtggtacag
    18961 aaaatattca gcgtttcttt tcctcttctc gtaacaggcg tggattcgat gaattgaagt
    19021 ggatcgactt tactgattta acgatgctga aagaattgac acctttagaa atttcagaat
    19081 tattatattt tggtcatatg aaaacacatc ttcattcgcc gtttttttat aaactacaga
    19141 ataattttgt atacttcgat cttaatgatc agctgaatcg gatttattat cgctatttag
    19201 atgaatttta taggattttt gctagtaaat taagttcgat cttgtcagat aagatcaatg
    19261 taaaaaaatc ttttttcaaa aaagaaacac ctgttgaaaa aatcagtgtg gaattattga
    19321 aagaaatgcg taatttgatg caggaaggga tcattttttc ttttgatcaa gttggtttga
    19381 tcgatggtaa atatcgtatc ccaatctatg tgattgaaga ttatatttgg aaattaaaag
    19441 gcacccggta tcgagaagag gaaatcatcg ctactttaat ctactctgtc accgatcgac
    19501 actggcaatt ggtagaagat gccgatcttt cttatctgcc attgaagtag atctatttct
    19561 tatcaaaaaa taaaaaggaa acaagaaact aggacatgat tctgtctcaa gtttcttgct
    19621 tcttttttat ttacagctcc tgtcgtttat ctggcacaaa aatcgaagga gtcgtttgtt
    19681 ggatccctaa taaaacgatg atcgttacaa tagctgtact caacccgctg gcaccattca
    19741 ttacgaaaga aaagagccaa ggattcatcc cccatagtgc atacgctccc cagaaaacca
    19801 ctcctgcaat aaaatgccaa aaatatctgg aaagtgcgcc aatcaatgca ccaaacacga
    19861 tgctttttct aatttgtttc gtattatcgt ctacatagcc tttttggaca tttgaagcca
    19921 tgagccctgc tgcgcctgca aaagtatagg caatcgggta ctcaatcaac acttgaacga
    19981 cacttaaata ataaacttgt cccaacggaa aatgtaggat gccccaaatg aaacctgcca
    20041 gcatccctgc ctttgtccct cttcttaacg caaaaagagt caatggaatc tgccctaatg
    20101 aaatagaaaa actgctgccg atctggatcg gaatcaacga caacaccatc gctaacgctg
    20161 caacaatcgt tccttctacc caaactctat tttttcccat aaaaaaactt cctcctttga
    20221 ataaaaaagt cacaaaggag gaagcagctt tcgaaaatag tcaaacagct gtttattcac
    20281 aattcctacg ctcgcataac cgatacaggt acgaagggtt tagaaataga ttcaatctca
    20341 gcccaattgg actccccttt gtgagtttat ttattattta ttttttgttt caaacaatgg
    20401 actaactggt ttgttttcat ggatacgttt gattgcatct cccattagtc cgccaacact
    20461 tacttcatcg attttgtcga ttttacgatc ttctggaaga tagatcgagt ctgtaacaac
    20521 tagacgctcg atagctgaat cttctattct ttgtaaagca gggccggata atactggatg
    20581 tgtacatgaa gcatacacac tagttgcacc agcttctttc aaagcattgg cagccaatgt
    20641 gatcgtacct gctgtatcga tcatatcatc gatcagtaca caagttttgc ctttgacttg
    20701 tccaatgata ttcattactt ctgcaacatt tgcttttgga cggcgtttgt ctatgatcgc
    20761 aatcggagat ttcaaaaatt ccgctaattt acgtgcccgt gtgacaccac catggtctgg
    20821 tgaaacaacg acaacatcat cgcctttgat tcctttttct aagaaataat tggcaataag
    20881 tggcgcaccc atcaaatgat cgactggaat atcaaagaaa ccttggattt ggactgcatg
    20941 aaggtccaaa gtcagcattc ttgttgcacc agctttttga atcatgtttg ctactaattt
    21001 cgctgtgatt ggttcccgtg cacgtgcttt acggtcttga cgcgcatagc cataataagg
    21061 catgactacg ttgattgttt ttgcacttgc tcgtttcagt gcgtcaatca tgatcagcaa
    21121 ctccatcaag ttatcattga ctgggctgct cgttgattga ataacataga catgcgatcc
    21181 acgaatactt tcttcaatgt ttacttgaat ttctccatca ctaaattgag taacagatga
    21241 ttttcctaac tcgacgccga ctgctgctgc aattttctct gctaatgggc gattggaatt
    21301 taacgcaaaa atttttaatc ttgggtcaaa gtaatgtttt gacatgggga cctccacttt
    21361 ctttttcaca actctagaat tctacctaat aaatagtagt catatttttt aaataaatca
    21421 agtgattttg caaaagtctt agtttagata agggagtttt tttgcatatc cttctttatt
    21481 gacttgtctt gctctcgcaa ttgccagcgc atattctgga atattgtctg taattgttga
    21541 cccggcagca atcgaactgt ttttagctac ctcgacaggt ccgatgatat tcgtgctaga
    21601 accaataaag ctgtggtcgc cgacagtcgt atgatgtttg ttctttccat catagttgac
    21661 gaagacaaca ccacatccga cattgatttc ttctcccagc gtagcatcac caacataagt
    21721 caagtgaccg actttagttc ctttgccgat ttgagcattt ttcacttcca caaagtttcc
    21781 gatatggacg ttttcgccaa tttcagcttt tggtcgtaaa tgtgcataag gtcccacatc
    21841 tgcatgtttc ttgacatggc tgctttcaat gactgagttt tcaatgacga cgtgatcctc
    21901 aatcctactg tctacgattt ttgaatgtga cccgatgaca caatcagaac caatgactgt
    21961 atttccttgg atttgtacac ctgcttcgat caatgtgtct ggaccgattt ctacgcctgc
    22021 atcgatgtat gtcgttgctg aatcgacaaa gcttacgcca ttgaccatat gcatctggtt
    22081 aattcgcttt ctcatgatct catttgcttt agctaacgcg atccgatcat tgactcccat
    22141 tgattcttca aaatcatccg tttgataagc agcaactgta tggccttctt cttttaagat
    22201 ttcgatgata tctgttagat agtattcacc ttgagcattg tttgttccaa ctttgcttaa
    22261 cgcatcgaac aaagcttcgt tgtcaaaaca gtaagttcct gtattgattt cttgtacaag
    22321 agcttcttct ggtgttgcat ctttttgttc cacgattttt tctacgatcc caatatggtc
    22381 acggatgatt cgtccatatc ctgttgggtt ttctgcttgt gccgtcaaga tcgttgcact
    22441 tgcatttttt ccttggtgat attcaaaaag attgttcagc gtttcagtag tcaataatgg
    22501 tgtatcgcca ctgataacta acgttgttcc tttttttcct tccaagaaag aagcagcttg
    22561 caaaacagca tgtcctgttc ccaattgttc tgcttgtaac gcatatttac tgcgttctcc
    22621 tagttgtgct ttaacttgtt ctgctccgtg tccaacgatc gtaatcactt catctggttt
    22681 cgtttcactg acccgattaa tgatatgttc taccataggt ttaccagaaa cgggatgtaa
    22741 aactttatat aattttgact tcatgcgggt acctttccct gccgccaaaa taattgcata
    22801 acgtgcgtcc aactgcgtca ctcctaaata tagtttgctg atttcagttt atcccagtat
    22861 acccattttt tcaacaaaac aagtgatttt cttttatccc agcgttttct ggataaaaaa
    22921 atagatagac cataacgggc ctatctattt ggtaaccggt gctctcctgc caactcctcg
    22981 gtcacaagtc acactactca taaaacatga aaagctgttt tttgaaatcg tttcttgtga
    23041 cttagagtta aacggtaggc ttacaacctc ttcattaaac gtttttcaat cagctgacct
    23101 tcggtattag ctcaataaac ggcaaaatat gaggagcaat ttttccgttt attgagctaa
    23161 tactcaggac aggacgctga tttcacaacc tctagataaa cggtgttcaa aagccagttt
    23221 ctcggtatta agccaaattt atgaaaaaat gtggaaagcc attttcacaa aatttttctt
    23281 actactcgaa actaagcggc tttttcacaa cctcttattc tgaaaaataa tttcctggca
    23341 caaccgtaat atttttcgtt tgagtatcta catctttgac ataaagcagt gacgtataat
    23401 catcgatggc gcgatgaccg ttgaattttg attcggcaaa tacagtgatg ccaacaagtt
    23461 ctgattcgaa ttcttcaatc aagctcttca ttccgttgac tgttccgccg cctttcatga
    23521 aatcatccac tacaaggaca cgtgaaccac gtttcaaact tctcttagac agttccatct
    23581 tttcaattct ttcagaagat ccagacacat agttgacact tactgttgat ccttctgtta
    23641 tttttgagtc ccggcgtaca ataacgaatg gcgcattcag ataataggac acagcttggg
    23701 caataggtac gccttttgtg gctacagtca ttacagcatc gattttttca ccaaggtatt
    23761 tagaagcaat gattcttcca acttgacgca gcagttcagg ttctcctaac aaatcagaga
    23821 gataaacata tcctcctgga agcagacggt cttgttctga tagacgttct gctagagatt
    23881 caatatattt tttcgcctct tcatatgaaa tttcagggat gaacaataca ccacctgcag
    23941 cacccgggat tgtttccaag gttccatacc ctcgttcttt aaatgttttc ttgatgattc
    24001 ccaaatcttc actgatagaa gatttagcag attcataacg ttcggcaaag cttgttaagg
    24061 aaatcaattc atgcgggtga ttcaataaat actgtgtcat gtcaactaga cgttcactgc
    24121 gacgtacttt cacctattcc aactcctttt aagaaatttt atcgttttac attatataag
    24181 tttttcttca aaaattcgag cattttatga aaaaataaga aaatagttcg gtatttatta
    24241 aaataaaaag aagcctataa aaaatttttc gtttttataa ggcttctttt ctttataatt
    24301 tagttatttt ttcttctgaa ggcaaccaat attcgtttga tgatatttac aatcaggaac
    24361 aaagcaataa agactaatgt gattgttgct cctggaggtg tatctagata aaacgagcta
    24421 gttagtcctg acagcatccc tagaaatcct acacaaacac tgatagcaat cacgacattg
    24481 aagcttttgc ctaatcgcat accgattgct gcgggaagaa ccatgattgc ggatatcaaa
    24541 agtgcaccgg caatcgggat catcacagca atagccacac cagtaatcac attgaacatc
    24601 atcgacatca aatgaacggg tagcccatcc acgtgggcgg tatcttcatc aaaagtcaga
    24661 acatacatcg gccgtttgaa taaaaagaac aatataccga tggcaacgaa taagattcct
    24721 aaaaagatga cttgctccca tgtaatggtc acgatcgaac caaacagata ggattggata
    24781 cttgttgctg aattccctcc gctcaaattc atcaatacta acgctagcgc caaaccacca
    24841 gccattaaaa tggcaatgga gatttctgaa taggttcggt agatcgttcg cagatactcc
    24901 aatatcacag ctgctaatac aacgactagc atggtcgtaa gtgtaggatt aaggttcaaa
    24961 aagaatccta acgctacccc tgctaaagag acatgagaaa gcgtatcagc catcagcgat
    25021 tgtcttctga tcactaaaaa cacacctagc atcggggcga ttccggcaat gaagatagcg
    25081 gcaagaaacg ctcttctcat gaattcatat gaaagcaacg ccattgagaa tcctcctttc
    25141 tcaccagtcg gatctgtctg tccgcatact gtttgatatc ttcatgatca tgggtgatca
    25201 ttagaactga tttcccatgg acatgcgcac tatgtcggag aagacgataa aattcatttc
    25261 tggattcttc atccatacct gttgttggtt catcaagaac aaataagtca gggtcagtag
    25321 caaaaatacg cgctaaactg attcgctgct tttgtccgcc agacaattca cctattcgcc
    25381 gatttcgcat atcccacatc cctacagctt ctaaagcacg ctgtacatgt tgatgatctt
    25441 tttcagagag acgcttgaac cagcggcctc ttggatatct tcctgaacgg actaattcga
    25501 tcaccgtact aggaaaacct gcattgaaag atgcaacttg ttgaggaata taaccgatac
    25561 ttaatttttt tccttcttga tttttctcag caatctttat cattcctttt gaaggtttca
    25621 gtaatcctaa cgatgctttc accaaggttg acttggctgc tccattttct ccagttaaaa
    25681 tgacaaattc acccgcatct acatgataag agacatcttc tagtacaggt tcatcatcat
    25741 agtaaaaggt caaatcagat atttcgatat aacgcacctt acaacctcca ttctaaaact
    25801 taattgatac tttcttttaa agctttcaga tttttttcca tgacagaaat ataattttcg
    25861 cctgctttga tttgttcatt agtcaagctt tctaaaggat tcaacacttc tagcttcact
    25921 cctgtttcat tcgacaatgt ctcagctacc ttcgaagagg cattttcttc aaaataaatc
    25981 actttgatgt tgtttttctt cacaaattct tttagctcag ctaagcgact tggtgtgggt
    26041 tcctgatctg gtgaaacgcc cgaaatcgct acttgtttta agtcgtattg attcgctaaa
    26101 taagcaaaag cagcatgctg agtgacaaat gtgcggtttg ttgcatcttt tagctcatcg
    26161 gagtattttt gatccagtgc ttcaagcttt ttgatataag catcggcatt cttcgtaaaa
    26221 gtttcctttt tatctggata tttttcgcct aattcttcag caatcgttct gacttctttt
    26281 atagctaata ccggatcgag ccaaacatgt ggatcgtatt catgtgaatg accatgccct
    26341 tcttctgatt cttcatgttc gtctgcttct tgcgattcta aacggtcgat tcctttagct
    26401 gcttcgatca tcaaggtctg tttgctatcc actgaatcct ttaacgaatc cacaaaaaat
    26461 tccatgtctg aactattata cacgaaaaca tctgcatcgg aaatttctgc tctttctttt
    26521 gcacttggtt cgaaatcatg cggctccgtt ccagcaggga tcaaaagttt cacgtttcct
    26581 tcatccccta cgatctcttt tgtaaaatca tacatcggat aaaaagtcgt aacgatcgtc
    26641 aaatcctctt ttttgtctgc ttccttgttc gtatttccac atgctgcaaa cagtaaagca
    26701 cctatcatta ccgtagctgt caaaagatat tttttcattt atatgctcct ttcaatgaac
    26761 aaatcggaat tttacgattt attaacgtga actaatgtat caaaataaaa aaacacagtc
    26821 aatagaaatc catcaatttc tgatttaagc atgtatattc ttgattaaat cgtaaaatgg
    26881 atgagttgct gctcatatct agccatttca ctacaataaa aaactgaaga ataccatttt
    26941 aggattcctc agtttttcat cacctatttt acttcttata ttttattgca gggttcgtac
    27001 taaataaact tcctcacaaa aaccttttaa cccattatat actctctgcg ctcttgaata
    27061 atgttgacac aaggcaaaaa cggttggtcc gcttccactc atcaatgcag catctgctcc
    27121 gtacttgatc atacgctctt tgatttgatg gatgactgga tgccgctttc ccgttatatc
    27181 ttctaaactg tttcccattt ttttgatcat ctgctgataa tcttgctctc ggatggcttc
    27241 agcaagtccg tggatgtctt gatgttggat ggcttgcgta tctacttctc taaacactgt
    27301 acgtgtagag acactcattc ttggtttgac caacacaacc cagcactgtg gcatagaagg
    27361 taatacttgg atttcttccc ctttgccacc gacaaatgcc gtacttccgt agacacagta
    27421 aggaacatct gtaccgactt ccaaaccgat ttctgccagt tcttctaacg aacagcccag
    27481 attccataat tggttgatcc ctcttagagc agctgcacag tctgtacttc ctccgcctaa
    27541 tccagctgct actggaatat tcttcttaac aaagatcttg acaccggttt tgatattgta
    27601 tttatttttt agcaataaag cagcttgata aacattgttc cgttcatcta ccggtaaaaa
    27661 tgctttattt gtttctacaa tgattttgtc ttctgttatt tcttcaaaaa atagatgatc
    27721 tgccaagtct acgctcgaca tcaccatttc caactcatga tacccatctt gccgtctata
    27781 taatacatcc agtcctaaat ttatcttggc tggcgctttt tcaatcaatt ccatcctctc
    27841 acccattcga aaagtctaag tcgcaagtat tctatcatag ggaaaaataa aagtatagct
    27901 tatgtctgcc tagtggttga ttttgtcatc gtttcaacag ctttcacaga attttctctt
    27961 cataatccaa acaagttcta gtgattctta taattctgtg agcacttctt ctgccaaact
    28021 cggaacattt cctttttctt ttcctatcag actgagtagc tgcatggtag caaatccgaa
    28081 attacttcct ttcctataag caaaataacg tccttcccaa tgatcgacat attttaattt
    28141 cttttcataa gcagactgga aggaatagaa aaaattacca taattatata cgatatgcat
    28201 gactttttct tgaaagaaag aaaaatctgt ttctccaaca ttagctaatg gagctaagcc
    28261 tagattggct tccgagtagc ccattttctc gtatacaata aacagattgg ctaacagata
    28321 gtcagctaat tcctcagatt ctttaggtaa gacccgcaac aaatcatatc ccgcctgctt
    28381 cttcgtcatc ggctgagcgg tgatgaagcc aacgactttt tgatctttac ggacaatacc
    28441 gacaccgcta gataatacat atgatttatc aaatcgtccc acagagaagt atttttctcg
    28501 tgcaccttga agccattttt gtgaaacttc atttacagct tgatgtaatt cttccggcag
    28561 ttgatcgtac caagtaaaat ggtatccttc tttcatcaaa cgttgatatt caagttgctg
    28621 actcagccga gacaagtctt ctgttgctag atcaacaatc cctgcttcac ctactttcgt
    28681 gaagtgaaaa cccaattcat gaagcatcac tacgtagctt tctgatatct tataaaacgc
    28741 aagctgatag cctaaacaat ctgcttgttt cataaactga ttcgttgctg cccgcatcat
    28801 tttaggattg ccaactggat ctcctaaaac aaagcatttg tttcctttga tctgataacc
    28861 aaaaacgact tgatcttggt cgtcttcttg gtaataaaaa taactgtaac ctgacaagcg
    28921 aagctgatgg cttgtagctg tgcctccgta tgtttccaat aaacggtcaa aacggtcttt
    28981 ttcgtactca ctgccaagct tcgtagtatc ttcagctaaa tattgataaa gcgccactaa
    29041 agctagcaat gagatgccca aaccaataag ccctgagaac cacacatcat ctgaaggaaa
    29101 caaaataaaa tgatttcctg ttattcgacc gactaaaaag cgtccgctgt gatagcctgc
    29161 aattgcgtaa acgataaaca aaaagccgaa caagctagca tcaaagatta tagctcccca
    29221 agaataaacg aattttgttc gataaaattc ttttctggat aaccacacag ctaacagaat
    29281 caagacatat accaatatca actgccaaga taacgtacgt gtgattgtat ttaaaatacc
    29341 aaaagatagt aaagcaatcg taggcagaaa tgcctttttg acttttactg aaagtgctct
    29401 agcaaggccg agtaataaaa agccaaccaa tagattcact gtctgatcta aaaaattgaa
    29461 tgagaacggc aataatactt gaaatagccg actgattgca gacagattag tgattgttga
    29521 tagaagtacc atcatgatcc ccgcaaaata gacagcactt acgagcacga tatgcgcaac
    29581 cttttggaaa aacagtcgcg gaatgttatc taaaaatcga ttgattttga ctcctgtatg
    29641 tgtgatgaac aatagaagtc ccgtcataaa aggtagaaca taataaaaca accgataata
    29701 taatagccaa actactgcta catcttgccg aacagacaat tgactcattc ctaagatcat
    29761 caaaacgtca aaagtcccca ttccacctgg gaccatcgtc agcattccta tcaatgtagc
    29821 aatcatgaac ataggataga tcgaaagcat cgaaatatct attctcatca acttgccgat
    29881 gatcaaaaat accgcaaggg ctcccgtcca ttgtccaaag gatgccagta gcagaccaag
    29941 caagcctttt ggataaaact cgaagaacaa tgtctttctc tttagataag caaaaaagaa
    30001 aatgactggt gctaaaaaac taccgccgaa aagccagatc caatagcttc gaaaaatact
    30061 ttctgactga ataaaaaaga catcaataaa tgtaagaaac gaccatacag acaaaccagt
    30121 cagcataaat agtgcgactt ttgatacagt ggctaaaacc atttttctat ttgtctgctt
    30181 tccataaaaa ctagcccgca gacttgctcc taccacacca ccaaaaccgg cgagattgtt
    30241 gatcgtgttt gttacccacg cagcaagaag aaactctttt ctttccattt ttggttttcc
    30301 ttgtttttct aagactctga tcgtcaccca atcatacaac aacatcggag tgacacccag
    30361 cagtccagcc agaatcatga gcaggatcgt catgcggctt tgttgtccca tcctttgcca
    30421 aatatcttgc caactcatgc cattagcaat atttgcgact tgatttgcca caaagactaa
    30481 cacggagccg aaaaaaatca gttttaaaat cagactatgt tcctttatcc attgcagcat
    30541 caagtatcgt ttatttttca cattttccca ttcctaactt gtatactttt gtgtcatacc
    30601 ccaatgttat cttatttatt ttaatttttc cactttagac ctgttctttg cttgcgatga
    30661 tagaaaaaga aagatatcct aatgctaaag gagaggataa catgaaagta ggatttatcg
    30721 gcacagggaa tatggcacaa gctattattg atggtttatt aaaaaaagga acagtctcga
    30781 aagaagaggt gttcgtttcc agtggacatt ttgaaaatgc acaaaaattt gctgctgaaa
    30841 ctggcgtcca tgcatgcaaa agtaatcagg aagttgcatc acaatcagat atcgttcttt
    30901 tagccgtgaa accaaaaatc attgaaaaag tattggaaga actaagagaa tatagccaga
    30961 aagtcttatt catttctatt gcttcaggaa aatcattaat agatttagaa acagcgcttg
    31021 aagatcctca ggcctccatc gtacgtgtga tgccgaatgt caatgtcagc gtaggagcag
    31081 gcgtttctgc gatttgcaaa aatgaagctg ccacggagga acagcttcag caagctacga
    31141 tgatttttga agcaatcggc agcgtctatc ctttagcaga atcagatttc agtacattca
    31201 ttggccttgc tggcagctca cccgcattcg tttacatgct gatcgatgcg atgggacgga
    31261 ctggtgtact gaatggtttg tccaaacaga cagccactga gattgctgca aaagcaatta
    31321 tgggttcttg tcaaaaattc ctttcaagtg ataaaaatcc atgggaactt gtagaccaag
    31381 tttcttctcc tggcggtaca actgttgcag gtgtagttgc cttagaagaa gcaggattca
    31441 tcccagcaat catcaaagga atcaatacga cgatcgagaa agatcttgag atgttgaata
    31501 aaaaataatg atagcaatgt tttttcgtgc cttacaaaaa aagaagagct gtggcttttg
    31561 ccgcggctct tcttttgtat tttttattat ttagcataat cagttgcacg agtttcccga
    31621 ataacgatta ctttgatgtg tccaggataa tccagttctt cttcgattcg tttacgaata
    31681 tcacgtacta aacgaacagc gtctaaatcc gagatttctt ctggcttgac cattacccga
    31741 acttcgcgtc cagcttgaac tgcgtaactt gattctacac cggcgaagct gttcgaaata
    31801 ttttccagac ttcttaaacg acggatgtag ttttctaatg attcacttcg cgcaccaggt
    31861 cttgctgctg agagcgcatc tgctgcagct acaaggacag agataacaga agtagcttcc
    31921 acatctccat gatgagaagc gatcgcgttg attactactg ggttttcttt gtacttggca
    31981 gctaattccg caccgatctc aacgtgagat ccttcaatct catggtcaag tgctttccca
    32041 atatcatgga gcaacccggc acgttttgct aattggatat cttcgccaag ctctgctgct
    32101 aagataccag ctaattttgc aacctcgacc gaatgcttca agacgttttg tccataacta
    32161 gttctgaatc gcagacgtcc gatgatcttg attagatctg gatgaagtgt atgagcaccg
    32221 acttcaaacg ctgcctcttc cccgtattcg cgaatacgtt catccatttc tttacgagat
    32281 ttctcgacca tttcttcgat acgcgctgga tggattcgtc catcttgtat cagtttttcc
    32341 aaggtcatcc gtgcgatttc tcttcggatt ggatcgaatc cggaaagaac aactgcttcc
    32401 ggtgtatcat cgatgattaa atcgatacca gtcagcgtct caagcgttcg aatattacga
    32461 ccttctcgtc caatgatacg acctttcatt tcatcattcg gaagggtaac gactgaaaca
    32521 gtcgtttctg aaacttgatc tgctgcgcag cgttgaatcg ctaatgataa taagtttttc
    32581 gctttgcgat ctgcttcttc tttggcacgc tgttcagatt cttttaccat tagagttaac
    32641 tcatgattca gctcttcttc agtcgatttc atgatgacat ctcgtgcgtc ctcttttgat
    32701 aaaccagcaa ttttttctag ttctttttgt tgatcttcaa tcattttttc aacgtctttt
    32761 tctcgctctt caattaattg ctgttttgaa ctaagtgctt cttctttact ttcaagtgag
    32821 ttctcgcgtt tttctaacga gtcatcttta cgattcagcg tttgttcgcg ttgaatcaaa
    32881 cgattctctt gagattttaa ttctaactta ctttctctca gctcactttc aacttcagaa
    32941 cggtatttct gattttcttc cttagcttct aacaatgctt ctttttttag agtttctgct
    33001 tctttttttg cactatcgat gattccagca gctgatgatt gtgcaccagc tatttctttc
    33061 tcgtgacgtg actttgcgac cataaaccct aaaccaagac cgacaattaa accgatgata
    33121 gcgaggagaa tgttgaatac cataaaatcc acctccatac tatctttttc atttttatca
    33181 tctatacagc ttctatgata aattattcta aactcgtcaa tatgcatctt cgcatatatg
    33241 tgtacaaaaa acatgcacaa ctttattcta atgtttgtac cccgtagtgt caactttaaa
    33301 taaacaaaga aacggctttc tacttattca ttaaacgatg gtttttaaaa taaatgacac
    33361 tagtttcata taggtaaacc tttaaattga gaaacttttc tattaaatta ttctttgtag
    33421 atgaacagat atttttattt tatgtaccca ctcgtataat taaataactc acgatttctt
    33481 tattcaataa aaaaacggca ggtcaaggag agtacctact cttcagacca gccgtttttg
    33541 tttatcataa tttttattct tctactaaag gcaattcttc ttgtcctttt tcatcttctg
    33601 ggacagcgac ttcttcacca ataccataag ctgctctaac tagagcagaa acttctgcca
    33661 tcatttcagg atgattagcc atatagattt tagcgttttc ccgtccttga ccaatccgat
    33721 cttctttata agaataccaa gcaccgcttt tatcaacaat gtctttttct actgccatgt
    33781 ctagaagttc tccttcttgt gagatcccta aaccatacat gacatctact tcagcgattt
    33841 tgaaaggagg tgctactttg ttttttacga ctttgatctt tgtacggtta ccaacaatat
    33901 ctgtaccttg tttcaattgt tctgcacgac gtacttccaa acggatcgtt gcgtagaatt
    33961 tcaatgcgcg tcctccagga gtgatttctg gattcccaaa catcacgcct actttttcac
    34021 ggatttggtt gatgaaaata gcgattgttt ttgttttgtt gatcgaacca gagagtttac
    34081 gcaatgcttg agacatcaaa cgtgcttgta acccgacatg tgagtcaccc atttcgccgt
    34141 cgatttctgc tcgtggaact aaagcagcaa ctgaatcgac tactacgata tctacagccc
    34201 cacttgatac taaagcatca gcgatctcta gaccttgttc tcctgtgtca ggctgtgaaa
    34261 gaagtagttc atcgatattc acacctaatt tttgtgcata ttgcggatct aacgcatgct
    34321 cagcatcaat gaaagcggcc gttccgccat ttttttgtac ttctgcaata gcgtgtagtg
    34381 caactgttgt tttacctgaa ctttcaggtc catatacttc gatgatacgt ccacgggggt
    34441 aaccgccgac acctaaagcg acatctaacg caagagagcc acttggaatt gtagagattt
    34501 gttggtcgat tttttcgccc aatttcataa tagagccttt accatagctc ttttcaattt
    34561 ttttcagtgc agcatctaag gctgctttac gatcatctgc caatacgata atcctcctta
    34621 tatttacaaa tcagagcaac atttcattat ccttatcata tcttttttag tgaaaaaaag
    34681 caagaaaaaa ccgaacaaat attcgcattt atcattttct taaaagctgt tttctcaaaa
    34741 gatcaaatcc ttgcataacc gcattatatc tgatagcagc acgatctctg gcaaagtgat
    34801 atttttccga aaccacgccg tctttagatg aaatagcgat ccatactgtt cctgcagatt
    34861 gaccttctaa cgtgtccggt ccagccactc cggtgaaagc tacactgtaa tctgttcttg
    34921 ctatctcacg tgcttgaatg gccatctgct ccacacattc tttgctgact gttccatatt
    34981 ctgctaatag ctccggatca atctccagaa aaccagcttt tgtttggagc gagtaggtaa
    35041 cgaatccgcc tggaaatact tcagatacac cagcaatgtc gcctaatgcg gcttggaagg
    35101 cgccggctgt caaactttcc gctgctgtta cagtctgctt gttttctttc agtagttcca
    35161 ctacgacttt tgctagcgaa ttatcatcgc cgtatccata aaaatattcc cctactcgtt
    35221 cttggatttt ttcttctaat gctaaaagag cttgattccc tgcctgaaca tcatttgttt
    35281 tcactgtcag tcgtaatgtc acttcatttg gtttggcata tggtgcgatc gttggattga
    35341 tctgtgtctc aatcagatct tttagctcag tgaccagtcg cgattcacca atcccataaa
    35401 agcgcaaaac tttagaaatt agtttttctt cagaaggaaa acgttcctct agtaaaggac
    35461 gtacttgttc cacaaacatt ggtttcaact cattaggcgg accgggaaga aggatatacg
    35521 catgtgtatc tgtttgataa aaagtcccta aagcaagccc tgtacgattt ggtagaggaa
    35581 ccccgccttc gataatctgg gactgttgca gattgttttt ggtcattttt cgatgggttg
    35641 tttcaaaata tgccaataat tttttgtatc cttccgtatt ttgtatgaga gacttaccga
    35701 ggtgagccgc agttgcttct tttgtcaggt catcttctgt cggtcctaat ccgccacata
    35761 agagtatgag ttcacttctt gtttcagcta gagcaatcaa ctcttctaaa cgctgctgat
    35821 tatctcctac aactgtttga taataaactt cgatacctag atcagctagc tgttctgaca
    35881 agaaagtggc attcgtattc acgacttgtc ctagtaaaag ttctgttccg acagctatta
    35941 tttctgcttt cattacttcc cgctccctta tatagtatac gctgtatttt tatatttttt
    36001 tatttaaaaa gagggcaagg agctgtgaca aaaatcttgt cacagctcct tgttccaaat
    36061 aaacagtgtt ctcctgccaa aacctcggtc ataagtcaca atatacataa aacatgaaaa
    36121 gctgtttttt gaaattatcc cttgtgactc agagttagac ggcaggctca caacctctcc
    36181 actaaacgat acttacattg atcctttgaa cacaccgctg tttttgatga agtaatccac
    36241 acctgaatag atagtaaaga tcagacaagc ataaagcatg atttgatcta ctggaatacc
    36301 gatcaggctg aatgggatat tattgataaa cagcaagata atagcaacca tttgtgtagc
    36361 cgtcttgact tttcccggcc aagctgcagc catgacttct ccatgttcga caagtagtaa
    36421 acgcaagcct gtgacggcta attcacgaca gacaatgatc gctactaccc aaccaggggc
    36481 ctttccttgg tcaaccaaca tgataaaagc agtcataact agcattttat ctgccaacgg
    36541 gtccgcaaac ttgccaaaat tagtgacaag gcctcgcgca cgggcaattt ttccatctaa
    36601 ccagtctgtg atactagcta aagcaaaaat aactgcacct actagctgtg tgacagccag
    36661 tgtggtgtct cctacgttaa attgtcccca atctaaaggt aaacctacaa ccaaaatgaa
    36721 aatcgggatc atacaaattc taagtacagt taatttattt ggtaaattca cactatcgac
    36781 tcctttcttc cctattctac gtgactatca gcgaagtttc caccgatatt atttactttt
    36841 ccaaatgaat ttattcaaag gagtattttt attgaaattg atctttttga attaacgaag
    36901 aaggaccgcg acacagattt gtcacgatcc ttctttttta tacctacaag taaacagatg
    36961 cgtaaactaa tttatacgat cattctgcgt attgaagagt aaggttcaca ttttttggac
    37021 tctgattgtt ttcccctgga ttaactggta cggattctcc attcgctttg atcgttgcat
    37081 tgcttgctgc accaatcgtg atggtcgcat ttgttgctgt ttccggtaac acggtactct
    37141 gtgtttcatt tgctgccagt gtcccttgat aaacataggc attgtctact agcacaccta
    37201 accatacacg attgacagca gtaaattcaa gggttacagg cttggtagcg tctgtgatat
    37261 ttactgcgat ggcactgcca gaatcttctc ctgtagctat tgccattttc ttttcttcac
    37321 ttgattttgt tgttgattct actgtagaag actctttggt ctgcgtgctt tgctctgagg
    37381 aagaggactc ctcgactgat ccttctactt taagcgaaga agctgtgtct ccgattattg
    37441 gatcagcttg acgatcttgc caagtcatat agcccacgac aacgacaatc gccaaagcaa
    37501 ccaatcctaa taaaatgaca ggaagacttg tccaaaagcg acttggatgc gattcttcct
    37561 gatgcattgc ttttctagaa gtacttactg tttcaggctg cggacgttca gggaccgatc
    37621 ctgtcaattt gcttttccca tcaaaaacat cgactaaatg gtctccatct tctcctacag
    37681 cttcagcgta ttgccgaata aatgcccgca cgtaaaattt accaggcaat tggtcaaaat
    37741 catcattgtc gattgcttcc aaataacgtt tttgaatttt tgtaatctgc tgtaattcat
    37801 ctaaagatat ttttttattc aggcgtgctt gccgtaattt ttctccgatg gtttcaaaag
    37861 ccactcgttc atcttctcca gtctgtttga ttctccgaag catctgctgt tgcaacgaaa
    37921 gacgttatgt ttgggtgctg tgacaaaagt catgtcacag ctcctttttt ccgaataaac
    37981 attgttctcc tgccaactcc tcggtcacaa gtcacaatat ccaataaata taagaagctg
    38041 ttttttgaac ttgttccttg tgactcggag ttaaacggca ggctcacgac ctctttctta
    38101 aacggtgttc aatcagctgt tcctcggtat tagctcaaaa accggcaaaa tataaggaga
    38161 tatttttccg tatgtttctc taatactcag gtcaaaacgc tgatttcaca acctcttcct
    38221 taaacggtgt tcaaaagctt gcatctgcgg taataagtcc aaccaagtta aaaacattaa
    38281 gaagctgttt ttacttggct gttcttatta cttgatgcag ggcagctttt tcacaacctc
    38341 ttggtacacg gtgttccaga agtagcttct tcggcaataa gccgaaatat cacaaaaatt
    38401 tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag ctgaccactt ctgtcacaac
    38461 ctctttgatt acttcgtttg attttatttt aatataagtt gattaaaaga gagcatgatt
    38521 tgttttattt tctcactaat ttttccaaca caactaagaa taccataaaa gctgattttg
    38581 gaggaggttc ctactacaag tctaaaacga aatttaagac ttttcctcat aaaatactgg
    38641 tttattttgg tctcatgtaa aactcgctga aggcctcttc acttataaat gcttccccag
    38701 ctgccagtac gtctttcatt tggatcgaat cgatgatttc aggaagatca aataaagttc
    38761 gatcgccaaa taaactttgc gtaaattgat tggcaatata ttcgatcgaa tttaatgatt
    38821 ggaaatattg tccaagcatt ttcttcttca gcaaatcgag atttgtttct gacacttccg
    38881 gatcatcagc gaatccaaga atgatttctt tgactttttc tgctgctttc tctggttcgt
    38941 ccgtatctcc gctgaagtcc gcaaagtgaa attcacgatc caagctgaat tcaaaaccaa
    39001 agctgtcatc gataattcct tgattgtaca tcgctagata gtttcgagaa gtattgccta
    39061 aaatcatttg gaacaacaga ttgattgctg ttttatagcg taacagttct gttccttctt
    39121 gcggcaatgt gtctaatcct ttaataccaa gtacaaattt atctcgtgta atggctgctt
    39181 ccaatgcact ttgtttgatg atttcttttg tgttttcagg gaaataacgt acaatttctt
    39241 gctttggagg gaaatttttt gcttcttggt tttcccgaat aagtttcatc aatttctcag
    39301 gctccatctt accaactaca aataaaacca tattgcttgg ctgataaaac gtccgatagc
    39361 acgtatacaa gtcttgagct gtgattttgt cgatactttc aaccgtgccc gcaatatcga
    39421 tatgcaatgg gtgtgtagga tacaagttat ttagtatgcc aaaaaacatc cgccagttag
    39481 ggtcgtcttc atacatttgg atttcctgac cgatgattcc tttttccttg tttacagttt
    39541 cttctgtgaa gtaaggtgct tgtacaaaat cgatcagagt cgtcagattc ttttctacct
    39601 gatccgtcgt agaaaacaga tagctggttt tcgtaaaact tgtgaaagca ttggcggaag
    39661 ctccttgttt cccaaataat tgaaagacat caccatcttc tttttcaaac aacttatgtt
    39721 ctaaaaaatg ggcaattcca tctggaactt tcaccttttc tttttcacca tagggaataa
    39781 attcgttatc gatcgaacca taattcgtac tgaacaaacc atatgtcttg tgatagtcat
    39841 ttttaggcaa caaatacacg gtcaaaccgt ttggcagtac ttcatgataa agtgtttcat
    39901 tgatttgctc atattctgtt ttattcattt gcatttcctc ctgctaaaaa gaagattgcc
    39961 tgcaattcga tttgctcagc tacttgttgt atctctttga tcgttacgct ctccatacgt
    40021 ttcaaccatt cttcatcaga taattttgtt tccggcagcc agctgtccaa aaaagaagct
    40081 tcgattgccg cttgcggaga gtctagagaa agcagatatt ggtttctcag cattgctttt
    40141 gtctgagaca gttccaactc tgttatttca ccatttcgca aactttctaa ttgctcgtga
    40201 atcagatgaa gtacttgatt tcggttcttt tcatcgatac cggtttggac actcatgaat
    40261 cctcggaacg tatccacgct actagaggca taataagcta gactttcttt ctctctgaca
    40321 ttcatgaaaa gtttagagtg aggaaaaccg ccaaataaac cgttaaagac cattagcgca
    40381 aaacgttctg gttcatcgta atacacattt gtctgataag ctaggttcag ctttgcttga
    40441 acgattggct cacgtacttg tcgttccttc acgatattca cttgaggttg ggtataaaac
    40501 agatctggat aaactgtttc ccgcgactca aatggtaatt gcccaactgc ttcagctgct
    40561 ttgtccggat caacatcgcc gacaacaaaa atgtcgattt gatcatttgc catcatttct
    40621 tgatagtagg acgctagcga actagcagtg atcttgtcca aatcttcgac tacgcccaac
    40681 cctgggatct tttgttccgg gctgttttca aaataaagtt cttgcaaggc ataggaagca
    40741 aaagtttgtt tatcttcctt caaactttcc aaatatagac gcagattgtt cttttccaag
    40801 tcaaacgtca actgatcaaa ctgatgattt ttaatatttg gataaaataa aacctctttt
    40861 aaaaaatcta ccgcttgaga aaaaaggttt ggatcattga catattcacc attcacaaaa
    40921 ctgatccctg cgtttagcca atgtaaattt cctttttttc taactgataa tccaaagctt
    40981 gcgccataaa gctctgcaag ttgcgcactt aactttgtct gatccgaata attcaaacta
    41041 tttgtttcca acatgctgct gagaagtgaa cgtttcgtga tgacttcttg ttgcagacgc
    41101 gcagtaaaac ggataaaaat ccggatcgtt ttgtattgtt ttgttggtaa gacatgaaga
    41161 ttcacgcctt ctgccaattg atacaccata tttatatgct ccttttcaca gttgattgcc
    41221 cgcttactct tttaatgggt caacctgcct tttttactta ttcctctgct tgaaatttat
    41281 aagttcaggc aattcgccgt tttttctaaa tgatgttaca ctttatagta tagcatagat
    41341 gttttttatc aaaagaaaca gacggctaaa agcgtatatt gtttttttat tttttatttt
    41401 tcgatatact aaagacaaat aaaagaaggg agggtcattc atgatcaaag aattcaaaga
    41461 gttcatcatg cgtggagatg tcttggatct tgctgtcggc gttgttattg gtagtgcgtt
    41521 tacaagcatc gtaaaccaag tggtgcaagg cttgatcaca ccactaatag gttggtttgt
    41581 cgcaatgatc acaggtactt ctgatttaga aggagcactt tcaattcttg actggtcgcc
    41641 gacaaaaggc gtcacatttg cgtttggtaa cgttattagt gctatcatta catttctgat
    41701 cactggtttt gtcttattct tagttgtcaa agcggcaaac cgtgcgaaga atttacgctc
    41761 caaagaagag caagtggaag tggaagaaac tcctactgca gaagattatc ttagtgacat
    41821 acgcgatctt cttgccaaac aagtggcaga agacaataca catccagtag agcaaacaaa
    41881 tctttccgat acttctaaat aataaagaat ctaaaaaaaa gaaagccgat tttcagtgtc
    41941 ggctttcttt ttttagattc ttaacttgct acttgttcct ttttcatgtc gatatgtgga
    42001 atatcatctt ccaaatacac atctgagatt gccttgaatc caaacgactc ataaaaagct
    42061 tgtaggtatt cttgtgcgcc gatcacgatt ggtttttctg gaaatttttc tggatcatgt
    42121 taatcgtttc ttgaacaatc tttcttccta aaccatcttt acggttgtcc tgatgaacaa
    42181 ggacacgtcc aaaatggata ctctccgctt cttcatatac tcgcgtgtag gcaaggatct
    42241 tcccatcagt atcttgaaaa aacgtatgcc aagcttctcc atcaatgtca tcaacttctt
    42301 gataaggaca ctgttgttcc acaacaaaaa ctgcgattcg ttctttgacg atcgcgtaaa
    42361 actctgctgt tgacaattct tcaaatttct ttacctgata ttccactaag caaacgcccc
    42421 ctgctttttt attcttagca taccgattcg cacacaaaaa agcaaacgaa ccttacgaat
    42481 ctcaggctcg tttgcttttt aaactgcttc agttaaaaat tcgatctcaa ctgtccgagt
    42541 aagtacatct gaatagctgt aagatactcg ttcaaaagaa ttttcttcag gatccaaatc
    42601 aacaacgaat actgaaggat aggtttctgt taaaacgccg cggcgttctg tttgacgctt
    42661 tcttcctgtc tgagcaacca acatgattgg gctgccgata cgaccttcta aatctttctt
    42721 gattgaagct aaagttgttg gcatacagtt cacctctact atcaactata ccacatattt
    42781 ttaaaatttt caagtttacc ataaaaaaaa aagaaatgca ataaaaataa ataagaagct
    42841 cattaagatt tttctaaatt attcctcatt ataaaatttc aagtgttttt ttattttgag
    42901 ttttactctc ccgtaagcgc tcattacttg cttgtgatcc attgctaaac attcagccat
    42961 gtctacaaaa tcaacgcctt gcatataata atgaaaaatt ttagcttcta tttttgaaaa
    43021 ctggatttcg caattttcga ttgcttcttt taataaaaga tgctgaattg ctaaaggttc
    43081 ttgcaatgtg atctctgcta aaaagtctgg tccttctgtc tctatttttt ggtcgattga
    43141 gacttcatct ttttgatcac gacgcttcag cgcgttctgc ttcctcaaca gagaatagat
    43201 ttgattgctt ataacgcttt tataataact tccaaagcta acacctttgc ttttttcgta
    43261 agttctcaat gcctgatata aagcgatcct tgcttcttgt tcccaatcct cagaaacata
    43321 atttcttaaa taataggtgt ttttcaaacg tagtaaaagt ggaaaatatt tttgatacag
    43381 ggcagcaaat gcttcttcgt caccattacg tgcagcgcgc aataactcct cagacataaa
    43441 ataattcctc cataaattcg tttatggagg aatcttatca tcaatgattc atcgaactga
    43501 ttagaacgat atgttattta ttttttctca ttaaatcgtc caatttttgg gacaattttt
    43561 ttaactgctc ttcattccat ggagaattac gtcggaaatc aataaaatgc atatctttat
    43621 tttcttgggc tattgttttt tccgtttttt ttatcgtctt atataattca taagcagaag
    43681 ttcgtaatgc tccttgggaa aagatcatcc actgttctgc taaatcgctt gtcgccactg
    43741 tcacttgtgt caaacggtca ttcagctgac cagcgattct ctcgatataa ctgtcagccg
    43801 tttcgtcttc tttcgtaaaa acaacatcca actggtattt cttataattt tgttggatgc
    43861 ccggaactag ttgggcatcg aagacaacga tgacttccat tccttcatat ttcgcataat
    43921 ttgataaacg atgtaaaaga gcttctcttg catccgccat tttgtcctgc tttttaagct
    43981 ggacaagttc cggccacgaa ccaatcatgt tgtagccgtc tacaatcaac agctgttttt
    44041 tcatggtcta ctccccctga cgttgggaaa aagcctgata cataagcaaa ccagcagcaa
    44101 cactggcatt taagctctgg acgtgcccgg tcatcgggat cgtcagcaat tcatccattt
    44161 cttttttcaa tcctggactc attcctttgc cttcattacc aatgactaaa gcaattgatc
    44221 ctttggcatt ccatttttgg aagtttgtgc cggtcatatc tgtgccaaat acccaaaatc
    44281 ctgtttcttt gagctgttgc acagcttgta ccaaattcgt cacgcgtgca acagggacat
    44341 gttcgactgc cccagtggaa gtctttgtta cgataggtgt gattccaact gctcggtgtt
    44401 ttggtatgat cacaccatcg acgccacttg cgtctgctgt ccgtaaaatc gacccaaaat
    44461 tgtgtggatc ttcgatgcta tccaaaatca aaaagaaggg gtcttctttt ttctcttttg
    44521 ttcgttcaat cagttggtca agggataaat attcataagg tgtaatcgca agaacgactc
    44581 cttgatgcac gccgtgatcg ctcaaagttt ctaatttttg tttaggaacc catttgactg
    44641 gcacagcttg ttcacgtgcg atttctttca gttcttctac tttttctcct cgtgaatctt
    44701 cttgaagaaa gagtttattc cctcgccctt gttgtagcgc ttctactgcg gcatggtgcc
    44761 caaagacgaa attatcttct aatgcttctt cattttgatc agaaactgac tgatttcgtc
    44821 cagtttgctt tttatttgaa tatctatttt gttttttgtc ttcaaatcca cgtttcgatt
    44881 gatgtttgtt tgttctttct ttacccattt ttttcaccaa ctttctgaat acaccagcgg
    44941 atcaattctt ccatccgctc ggtttgtttt gtcaaatgca gatagcccat gagcgcttcg
    45001 aaccctgttg cgacccgata cgtcgtaaca tcagcatttt ttgcgctcgt atggctttta
    45061 gcatttcttc ctctgcgata ataaagttct tcttcttctg tcaaaagatg ttcttccagc
    45121 atttgctgaa tcaaaaaggc ttgtgcattc gcagaaacat aattcgttgc cgcacgatgc
    45181 agcttattgg gttttgtttc tccttgatca atcaggtggt cacgaacata gatttcgtaa
    45241 atcgcatctc caacataagc caaggctaaa ccgttcaatt gtgtgtaatc tctcatgctt
    45301 ctcttctcca tcgggttcct tgcggtgtat cttctaataa gatccctttt tctttcaaca
    45361 aatcacgaat ttcgtcgctt cggacaaaat cacgattgct tcttgcttga tttcgttctt
    45421 cgatcaattg ttcaatctct tcatctaata actcttctgc tgtaaataaa ataccgaaga
    45481 tcgaaagcca ttgcgagaat aaagcttctc cttgtgccaa gacagcggca gaaactttcg
    45541 gctggtctag ataagtgttc agccacttag caagctcata gaccactgtg atcccatttg
    45601 ctgcattaaa atcatcgtcc atttcttcga tgaatcgctg ttctaaattt tctaacaaag
    45661 cgattttatc cgcatcatct gccaaattct ctgaggcagt ttcttggcgg aatttcaaat
    45721 tgtcaaacgt attcttcagt cgttgtaaat tggtggctgc ttctttcatc gtcgtttcac
    45781 tgtagcggat cggacgacgg tattgtgtgg tcgccatgaa gaaacgcaag acttgtggat
    45841 caacgttttt gatcatttca tgtacagtga tgaaattccc tagagattta ctcatttttt
    45901 catcgtcttc gccaatcgtt acatagccat tgtgcatcca gtaattagcg aattttttcc
    45961 ctgttttcgc ttcactttgt gcgatttcat tttcatgatg aggaaattct aaatcttgcc
    46021 cgccaccatg gatatcgatc gtttctccta aatgttttgt tgccataacg gaacattcaa
    46081 tatgccaacc gggacgtcct ttgccccatg gtgaatccca agaaatctcg ccaggttttg
    46141 cttgtttcca taaagcgaaa tctaatgggt cttctttttg ctgctgttct tcccctgtac
    46201 gctgacttgc tccgacttcc agttcatcga tggattggtc acttaatttc ccataatttt
    46261 caaatttacg ggtacggtaa tacacatcac ctgaagattc ataagcatag cctttttcaa
    46321 ccaacacttg aataaatgct aaaatatctg gcatatgatc catgactctt ggatgcagtg
    46381 tagcaggttc gacattcaac gctttcgtat cttcttcaaa tgctcggatg aaacgatcag
    46441 caacttctgg tgctgtaata cctaattcgt ttgctgtacg gatgatttta tcgtctacat
    46501 ccgtgaaatt cgatacgaaa tcgactttat agcctcgata ttcaaaatag cgtcgaattg
    46561 tatcgaaagc aatggtgcta cgagcatttc cgatatggat ataattatac acagtcggtc
    46621 cgcagacata cataccgaca tgtccctttt gtatagggat gaattcttct ttttttctgg
    46681 tcaatgtatt gtagattttt atcattctga tctcctcact ttttctcctt tgattcgaac
    46741 gacttttgct ggtactccta ccgctgtagc gtcgtctgga acatctttca acacaacggc
    46801 acctgcaccg attttggcgt tttttccgat cgttaccggt cctaatatct gcgcattcgc
    46861 agagagcatg gctccttgtt taacagttgg gtgtctttta cccgtttctt ttcctgtgcc
    46921 gcctaatgtt acgccatgga ataaaatcac atcgtcctcg atttctgcgg tttcgccaat
    46981 gacgattccc attccatggt cgatgaacac gccagttcca atcgttgctc ctggatggat
    47041 ctcaacacca gttaggaaac gccagaattg agcattgatc ttcgccaata aaaagagccg
    47101 gtgctgatat aaaaaatgag agaaacgatg ccaaaacaag gcatgaaaac cagggtatgt
    47161 caaaacgatc tcagctgtcg aacgtgcagc cggatcgttt ctctttgctg catcaatcgc
    47221 tcgggtaaac caactcatga ctttccactc ctttcgtaag aattttatgt aggaaatcat
    47281 cttcttataa agaaaagaag cgccttttaa ataagtttcc ttatcaaaag acgctttccg
    47341 cgtggttcca cttttcttca taatcaatga ttatctctga cagctaacgc ctgttatacg
    47401 ttcttggcta ctttgtttcc tataaaacag tttttcctgt tttctgtgtt tcgccaagac
    47461 cactcccaga ggcatttcgg caaccattca ttgatacctt gcaccacccg gtatctctct
    47521 tgtaatgatc agctgcttac ttttttctgt tcatcgtgtt tagttcagta cttgatttaa
    47581 atgtgctaat gatttttcac gaccaagcaa ttcgatcgtt tcaggcaatt ctggaccatg
    47641 catttgtcct gatacagcta cacggattgg catgaaaaga ttttttcctt ttacgccagt
    47701 ttctttttga acagctttga tggcagcttt gacagttgga gcatctacta cttccatttg
    47761 ttctagctgt gctttgaatg cgtggagaac agtaggaact gtttcaccag caagtacttc
    47821 ttttgctgct tcattcaata caggatgttc attgaaaaat agcgtagaca gatcaacgat
    47881 ttctgcagca tagctcattt gaggttgata caggctaacg atcttcttca cccattcgat
    47941 tgtcttttca tctgggtttt ctgctacacg tccatcagcg attagataag gcagacacat
    48001 gtcagtaaat gcatctagat ccattgcttt gatgtaatgg ttgtttaccc attgcagttt
    48061 tttcgcatcg aaagctgcgg gtgatttact taggcgtttt ggatcgaaca ttttgatcaa
    48121 ttcttggtgt tcgaagattt cgtcttcgcc cacaggtgac cagcccaata atgcaataaa
    48181 gttgaacatt gcatctggta gatagcctaa ttcgcgatat tgttcgataa attgcaagat
    48241 tgattcgtca cgtttgctta gttttttacc tgtttcactg ttgatgatca atgtcatatg
    48301 tccgaaggtt ggtggtgtcc agccaaatgc ttcatagatc atcagttgtt ttggtgtatt
    48361 ggcaatatgg tcatctccac gtaaaacgtg agtgattttc atcaaatgat catcgaccgc
    48421 aacagcaaaa ttataagttg gcataccatc gcgtttttgg atgacaaagt cgccaccgat
    48481 attatcggat tcgaacgaaa tagcgccttt caccatatct gtaaatgcgt attctgtatt
    48541 gcgaggcaca cggaaacgta caacagattc tagaccttgt gcttcttttt ctgcttgttc
    48601 ttcaggtgtc aagttcgcac atgttcctgc gtaatgaggc atttctcctc ttgcgcgttg
    48661 tgcttcccgt tctgcttcta attcttcttc tgtgcaatag catttgtatg ctcgattgct
    48721 agcaagcagc tgatcaatca gcggttgata gatttcttta cgttcagatt gacggtaagg
    48781 gccgtattct ccaggatttt caggagattc atcccaattc attcccaacc aagcaaggtt
    48841 ttccaactgg cttttttcgc catcttcgat attacgtttt tggtcagtat cctcaatacg
    48901 aataataaag tctccatcat tgtggcgggc aaacaaataa ttgaataatg cagttcttgc
    48961 atttccaata tgcaggtgcc cagttggact tggtgcatag cgtacgcgta ctttcgtcat
    49021 tttcttcctc ttctttcaaa ctagactttg actaacagca aaaattccgt cagttacggc
    49081 ttctcaaata tcatttattt aaagccactc agcacaaatt ttaccttttc taaggtaaat
    49141 agtaaagcca actggttgaa tttccttacc agttggctga atttcttttt tattttgatt
    49201 gtttagtctt tttctctgtc tcttttttat tgtcgattcc tcgtcctgca tgtgcaggtt
    49261 tagcaaagat catgcgtcca gcagctgttt gaagggcact tgttacaacg acttcgatac
    49321 gttcattcat gtaatgctgt ccatcttcta cgacaaccat cgtgccgtca tcaaggtagg
    49381 ctactccttg ttggcgttct gtcccggctt ttactactag aacattcatc gtttcaccag
    49441 ggatgacgac tggttttacg gcatttgcca acgcattgat attaagaaca ggtacatttt
    49501 ggaattcaga gactttattc aagttatagt cattggttac aatgacacca tctaaaagct
    49561 tagccaattt gatcaatttg ctgtctactt cactgatatc ttcaaagtct ccatcgtaca
    49621 tttcgacaga tataccctct tctttttgca aggcatttag gatatctaat ccgcgacgac
    49681 cacgcacacg tttcaaacta tcccctgagt ccgcgatgta ttgtagttcg taaagaacaa
    49741 aattagggat catcaaggtt ccttctaaga atccagtctt tgtaatatca taaatccgac
    49801 cgtcaatgat cacgcttgta tccaagattt tatatttatg gaaattttct cctgattttc
    49861 gttctaacag ttgactctca acttgactag ctgtttcttg ctcgattttt ttgcttcgtg
    49921 aaccaaaaac tttcttccat tcttcgattc gtgtcgttcc cattctcaat cccagatagc
    49981 ctaagatgat catcagtaaa atcggcaata cactattgac gaatggaatt tccatattgt
    50041 aaagaggggt cgagatcaca acacctaaag tcaatccgat gatcgcaccg atcgcaccga
    50101 agagaagata agtcaagctg acctcactta gtttttgttc tacttgtttg ataatagctg
    50161 agatatgttt ggccaacagc aaagataata aaaagaaaat aagtgcgcct aacaggctgt
    50221 tggtaaatgt attattcagc catccgtttg actgttgacc gattgcctgc caagctgagg
    50281 gtaaaaatga aatacccaag cttgcgccga caatgatcat cagcaaagta atgacacgtt
    50341 tttgcatcgt ttttcctccg tttcgacaat catttattag ttagcggaac acacgcttca
    50401 acgtttcagc caaagttgct actccaacta tctcgattcc ttttggcgct tcccagttac
    50461 ctaagttgtt tttaggtagg tatacttttg tgaagccgag tttttggact tctttgactc
    50521 gttgttcaat atgactgaca cgtctgattt ctccagtcag tccaatttca ccgatgaaac
    50581 attccgttgg ctgtgttcct ttttctttat agcttgaagc aatactgaca gcgatagcta
    50641 aatcaatcgc tggttcattt aattttaccc cacctgcagc ttttaagtaa gcatcttgat
    50701 tctgaagaag caacccagct cttttttcca gcactgccat gatcagagat acccgattga
    50761 aatcaagacc tgttgttgtt cgtttggcat ttccgaacat agtaggtgtg actaatgctt
    50821 ggatctctac caaaattgga cgtgtccctt ccattgccac aacgatagca gagccagttg
    50881 caccgtctag gcgttcttct aagaaaatct gtgaaggatt agcgacttct tccaatccat
    50941 gctcatgcat ttcaaaaatc ccaatctcat tcgttgagcc aaatcggttt tttactgctc
    51001 gcaaaatccg aaaactatga tgttgttcac cttcaaaata taacaccgta tccaccatat
    51061 gttctaacat tcttgggccg gcgatcgagc cttctttggt aacatgaccg acgataaaaa
    51121 tggctatccc atttgtttta gcggttttga gtagttctgc agtggtttct cttacttggc
    51181 tgacacttcc tgccacactt gtgatgtctg gctgcgtcat cgtttggatg gaatcaatga
    51241 taacataatc aggggagata tgttcgatgg cacgactgat ttcgttcata tctgtttcag
    51301 cgtatagata aaattctgtg ttgatacttc cgaggcgttc cgcgcgtaat tttatctgct
    51361 ctgcgctttc ttcgccggat acatataaga cttttccgcc tatggctgct aattgctgag
    51421 aaacttgtaa cagcaaagtg gatttcccga tacctggatc gccaccaatc aagaccatag
    51481 accctggcac cacacctccg cctaacacac ggttcagttc ttctaatttt gttttgatcc
    51541 gaggttcttt tttagggacg acgtctgcga tttttgttgg ttttgctttt tctcctgtca
    51601 aacttgtccg agttctgcgg tccgttgtat cttgttcgat ttcttcgacc atcgtattcc
    51661 attttccgca atttgggcag cgtcccaaga acttaggcga cacatacccg caattttggc
    51721 aaacaaattg tacttttgat ttttttgcca ttgtaccgcc tccttttatc ctaatcatga
    51781 gacattaaat caagcttaag tatctttaac gttttattta ctggaagaac caaatccgcc
    51841 ttgacgttga gcagtcgttt gatcttgatc tgcttttaaa aacggcaaaa agatcccttg
    51901 gccgatacgc tcgccttttt tgatcactac atccttgaaa ccaaagttgg tgaattggaa
    51961 catgatatgg ccttcatttg cctcattatt gtaataatca ctgtcaatca cacctactcc
    52021 gtttgtcaac actaaaaacc gcttcaacgg attgcttgaa cggttagcaa gctgcaaaaa
    52081 ttcatcttct cccatgtaag ctttgattcc agtaggcacg agggttggtt tcaattgttt
    52141 ttcattttct gatacatctt ttttcaatcc atctgcgact gtttccaacc cctttttcca
    52201 gcctgctttc cagatacttg gaatcacgac ctcttctgct gcttcaaaat catagccagc
    52261 agcatgatgt gtagcgcgct gcggtagatt gatattttga tctttatatt tagaaataac
    52321 ttcaaatcct ctttttctca ccggttttcc tccctaaata aactactcct attctaacat
    52381 atccgaggct gtaaaagact ttctttacaa attcttcaag aaattctgct atcttaaagt
    52441 aaaccattaa ttcgttcttt ttccaaacga ctgcaagttg tacaaaaaaa ctatttttta
    52501 catgacttta ctcgtcaaaa caagtagaat agaacgaaat taatgagtgg atatttgatt
    52561 gaggtgtcac atgcgtaaag aaattaaaaa tgcaaaacga attattgtca aagtaggaac
    52621 aagtacattg atttatccca atggaaatat caatcttgcg gcaatcgatc agttagcttt
    52681 tgtcctttct gatcttagaa atcggggaaa ggaagtgatc ttagtctcat caggagctgt
    52741 aggcgttggt atgcataaat tacatttgtc agaacgtccg actttgattc ctgaacagca
    52801 agctgcggcg gctgttggtc aagccgaact gatgaatatc tataatcaaa gattcagtgt
    52861 atataatcaa cagacggcac agatcctcgt gacaagagac gtggtagatt atcctgaaag
    52921 tcgtaaaaat gtgaggaata cattggaaca gcttttgatt atggacacga tccctatcgt
    52981 gaacgaaaac gatactgtag cagtggatga attagatcat ctgacaaaat ttggcgataa
    53041 tgatcagctg tcagccatca tggcaaaact tgtcgcggca gaccttttga tcgtcctttc
    53101 tgatatcgac gggttttatt cagataatcc gactacaaat cccgaggctc agatgtatcg
    53161 ctatatcgat aaaatcgatg aaaagattct ggcacaagca ggtggtgctg gtagcacatt
    53221 tggaacaggc ggtatgcaga gtaaattaaa agccgcttct aggatatttg aagcaaacag
    53281 cgcaatgatt ttagcaaatg gaaaaaatcc ggcaattatt tttgatattc ttgcaggaaa
    53341 agaagtaggt actttattta aggaggactt gaaatgactg acttgatgca attaggacaa
    53401 caggcaaaag atagcgcgca acaactagca cttatgccta caaaccgcaa aaatgagcta
    53461 cttgttcaaa tggcacaaac catcaaaaag aatcaacaag cgatcattga agcaaatcat
    53521 aaagacttag aaaaagcagt cgaaaacaat atcagtgaaa cgatgcaaga ccgcttgcag
    53581 ctgacacctg agcgaatcaa tgccatggct acagagatcg aaaaaattgc ttcgttagac
    53641 gatcctattg gaaaagtaga tgagatgtgg acgaacaccg acggattgag aatcggcaaa
    53701 aagcgcgtgc cactaggcgt gatcggcatc atttacgaat ctcgtccaaa tgtcacgaca
    53761 gatgcagcta gtctagcatt caaatcaggg aatgccgtta tccttcgcgg tggcaaagaa
    53821 gcattcttct cgaatcaatt attagtccaa ttattgcagc aagtactggt cagtgctggc
    53881 gaatctcctt atgccatcca gtttgtcgat gatacttctc atgaaactgc aggacagttg
    53941 atgcgattga cagaatactt agatgtgctg attcctcgag gcggagcaaa attaatccaa
    54001 cgagtcaaag aacaggcaac ggtacctatc attgaaacag gtacaggaaa taatcacgta
    54061 tatatcgata aagaagcaca gttatctatg gcagtgaaca tcatcgtcaa tgcaaaagct
    54121 tcccgtccat ctgtctgtaa cgcggcagaa acattgctga tccattctga gatcgcacct
    54181 tttttcttgc cagctattga aaaagaactg gtagaacacg gggtctcttt acgtgcggat
    54241 gctcgtgcgt tagaatatct agagacggct gctttagcag aagacacaga ttgggatact
    54301 gaatatctag attatatcct tgctgtcaaa gtggtcgatt ctttggatga agcaattgca
    54361 catatcaatc ggcataatac taaacattca gaaacgatcg tgacagatag ttatgcggct
    54421 agtcaacgtt tcttaaatga agtggacgcg gcggctgtct atgtcaatgc ctccactcgt
    54481 tttacagacg gatcggtatt tggttttggt gcagagattg gtatctctac tcaaaagttg
    54541 catgcccgtg gtccaatggg gttaaatgaa ttaacttcca caaaatatat catttatggc
    54601 gatggacaaa tccgcgaata atgtttcgtg tgaaacatta ttcccgcctt ttgccttttt
    54661 tctgtaaagg ttctatccaa ctagaaaggt gtcaatatgt ttgaaatttt aatgattttt
    54721 tttatttacc ttatttctct gaatatcgct gcttttctgg gagtcggtat tttatccctt
    54781 ttctttcaat tcaaaaaacg aagcataggg agtcaacggg aaaaatggtc gcagtatttt
    54841 gacaaaatcg ggcaaaaagg gctggttaca cgcttgcaca ttagttacat ggttgcatta
    54901 tgcttattag cgacaatcaa ttactattct tttttcgatc attcaatcgc ttatacgatt
    54961 acgctactga ttgctgggat ttttcactta tcttataaat atcagctgaa taaaaaccac
    55021 ttgaatcgga ctttccgcta aaaaatatcc gtacgataag tagagtgcct tgaagatcgg
    55081 caaaaaactg ccggactttt tagaggctgt gacaaagatt ttgtcacagc ctctttttcc
    55141 atataaacgg cgttcgccta ccagctgcct ggtaaatctg tttcctcttc gttaagaagc
    55201 gaaaatccgt caaatgtttc gccatcataa taacgaagca gctcatccat ggacaagttc
    55261 atcgtttttt ctttttcttc ttccgctgat tcagccagta gctgttcccg atacacctga
    55321 tacataccag ctattttttg ctgcatcgct tttctagttt caccttccgc attgattatt
    55381 ggcaattctt tgatatagcc acgataaatc aaccgatcat ctgaaaattc aatgggtaat
    55441 tcaacgagtg tcaacccgac ttcctgaaaa tattcttcca gcatctatta tccccccatt
    55501 ctttttctta aatgaatttt agcttaccta ctgaaaattt tccagtttca ttattttgag
    55561 aaaaaaaggg aatgtgacaa aaatcgtgtc acatcccctt tttccgaata aatggtgttc
    55621 ttctgccaac tcctcaatca taagtcacaa tattcaacaa acatgagaaa ctgttttttg
    55681 aaattgttcc ttgtgattca gagttaaacg acagtctcac aacctcttgg taaacggcgt
    55741 tcaatcagct gaccctcggt attagctcaa aaaacggtaa aatatgagaa gctatttttc
    55801 cgttttgttt ctctaatact taggataaaa cgctgatttt acaacctctg ttaaacggtg
    55861 ttcaatcagc tgtccttcgg tattagctca aaaaacggca aaatatgagg aactattttt
    55921 ccgtttgttt ctctaatact caggacaaaa cgctgatttt acaacctcct gataaacggt
    55981 gttcaaaagc ttgcatctgc ggtaataagc ccaaccaaac gaaaaatatg agaagctatt
    56041 tttgtttggc tgttcttatg acttgatgca ggacagcttt ttcacaacct ctgatttctt
    56101 attcttcttc atttgtagca aaataattac ggtgataaat gatacaacat acactgataa
    56161 gaacaatggc acctgcaaaa taaaacgcat agctttcacc aatatgttca ccaatcacac
    56221 ctgcaataaa tggtgctaaa gctccaccga aaaagcggac aaaactatag ctggacgaag
    56281 caacgtttcg ttgcagacct ggtatttcca tagcaatcgt cgtcaacagt gtattgataa
    56341 ttccttggaa aaatcctgct aacacaatgc tgatcggtac aaggactggc atagaagttc
    56401 cagctcctaa taacagcaaa caaataatga ataagacaaa tgctgctaaa attgtccgat
    56461 aagtcgtaaa cttccgctca agagccggtg caacgaaaat cgaagcaata gccagaagca
    56521 caccccagcc aaaaaataca aaaccgactt ctaattcaga atagccaatc aataaaaatg
    56581 gcgcatacgc aagtaaagta aagaatccga aattatataa caatgcgatt agtccaactg
    56641 aacgaagttt atgattgctt aacgctttga caccttccca aaggcctact tttctctttg
    56701 gtttctcagt ttcaggtaaa agtaccgcta gggctataaa accgcaaaac atcaaaaatg
    56761 ctaccccaaa aaatggataa cgccatgaac cactgcccaa gaccccaccg actagagggc
    56821 caacagccat tccgcagcca agtgctgctt catacatcat gattgctttt tctgtgttac
    56881 caactaaaat actgacgatc gttgctaaag cagtagagac aaataaagca ttcccgacac
    56941 cccagccggc acgtaaccca atcagcattc cgatattccc agataatccg ccaagaccag
    57001 cgaatacaac gatgataaac aatcctgtca tcaatgtttt tttcaaaccg atccgactag
    57061 ataagaaacc tgtaaatagc atcaccacac cagtgactaa catgtaacta gtaaataaca
    57121 gggtcgtttc agctggcgta gcgtttaact gtgcagcaat cgtttttaag attgggtcta
    57181 ctagacccac tcccataaaa gcgatcatac aggtagctgc tacaactagc gctgaacttt
    57241 tcccctttgt ttcttcattt gtttgttctt gtatatctat ttgattctcc aatatttcca
    57301 tccctttctc tctattagca tcatacatga tttattttac atgtcaatat gcacatgtaa
    57361 aacgtggaaa ctttactgtg atataataaa gaaaataaga cgagaggtag gatttttatg
    57421 aatactttag cctatatatt attatgcgtg cttttatcca aaccacgttc tgggtatgaa
    57481 ttgaagcagc tgatcacaat tttttgggaa gcccatcaca gtcagatcta tacaacgctt
    57541 gccaagttag accagcaggg ttatgtgacc gttttggaca aagacgagca ctctcaaaaa
    57601 aagatctacc acttgactga tgaaggacgt gctcttgtag aggaatggat caaagaggaa
    57661 actcccgctc ctacgcaaaa agatgaattt ctagcaaaaa tctatgcttt ttcgacgctc
    57721 gataaaacaa cagctactgg actgctattc actagagaac aacagctgaa caaaatcatg
    57781 caaaaaaatc aaaaaaaatt gaatgacctc tcgctagaca agaaacaaga atttggacgt
    57841 tatgttgtga tccagcgcag aattatgctt tgtcagcagg aactccaatg gtgtcagcaa
    57901 gtaagagaac aaatgcagca gttttttgag taagggataa acagaacctt tctagaaata
    57961 tctattgaag agcaaattat cttcaataaa agagcaatac agttggaaaa gaaaaagcga
    58021 tccgaacgac aggccaaaac ctatcgttcg gatcactatt tttctagaac tgcattcaag
    58081 agactatgac aaaaagcatg ccaaggcctt ttttcaaata acagtgttcc atcattcatt
    58141 actttgaatt gcttttagca cacttcttga aagcgggcca acgatgatca actgcaacgg
    58201 taaagcggca atcacattca ttttccaagc attcatataa gcagagaata attgatcagg
    58261 tattccttgt tccatgatca caccgaataa agacatacat gtcaccattc ctaaaaccat
    58321 caagcatgaa atagttaaga tcatttggac cttgctttct ggatttactg gtagtttaaa
    58381 ggcaattttt ttcgccagca caccgatgat gaagacatcc aaaatgaaag ccaccacgaa
    58441 tccaggcact agaccaatca acaaacttga taaatgaaga tcttgatgca gccataaatt
    58501 atacgcgctc atccccaaga ccatcaaaaa acacatcatt gttgtaaaaa ttattccttc
    58561 ttttttattt gtaggcaatc tgtaccactc ctttaaattt gtcacgaaaa tcatcgtagc
    58621 acatttaaaa atttctcgta agtacttttt ttattttctg cccttttatt tcataaactt
    58681 catcagccgt acgctcgaca aagtaagaat catgagaagt aaacaaaatc gttcccggat
    58741 atatttgcat tagcttctct aaagcttcga tcgttgccat atcaataaaa ttagtcggtt
    58801 catctaacag caacacatta cttggcttag taaaaagcaa agcaatcgtc agacgggtcg
    58861 cttctccccc acttaatgta cataacggtt tcgtcaaagt ttcctgagca aaccctaagt
    58921 gattcagcaa actacggaca agcgattctg aaaactctgt ttgtctcatg acaaaacgaa
    58981 tgatggattc ttcagatgtc atttgataac ccttttgctg atatacttga aagcttactt
    59041 tcggagagag aaggattcct tctccttgtt tgcggatatg ttctaataag gttgtcttac
    59101 ctgaaccatt ttcaccgaca atcgcgattt ttttacctaa agaaaactga aaatcaccat
    59161 ttaccagtaa tgttctccca cttctttcca attggacatt ttgtcccatg atgggatagc
    59221 ggctgtggag ttcaagagat tttggtactg gaaaacggat ttgtttcatc tgctgcggct
    59281 tggttgtttc tcctattttt tggagtcttc tctctaatgt tttcgcattc ttttggatgg
    59341 ctttttgtac actgtctttt tgtttagagg aagacaaccg atccagtctg atttgttgct
    59401 ttttcttttt actggacact ttttccaact tttccgcttg ttttttcttt tcttggatcg
    59461 atttttccaa tcgttttttc tctttcatga tcgactctgc ttctcgtagc tgagtctttt
    59521 tctccaattc cttttgagtg agataggcac tataattccc cgaaaactct cggatttctc
    59581 cgtcttttac ttcccagatt ttcgatgcta gctcatctag aaaatagcga tcatgactaa
    59641 caaaaaccag cgtaccataa taataacgaa gctcttcaat cagtcgatca atactttttc
    59701 tatctagatg ggttgttggc tcgtctagaa gcatcccttg ttcataagaa gaaagaagac
    59761 gtatcaactc gatctttcgt tcttcccctc cgctccattt ccgctctgaa gtttcttcca
    59821 gtcttaactg gaaatgactg gctaattcca aatttaggtc ctttgcttca gcgagatagg
    59881 ttaattgagg caggtagttg aaggtgatct ctgtttggat tttcccatga tcgggaaaaa
    59941 gttcaccggc tattagtttg agcaaagtcg atttaccgac accattttct cctatgatcc
    60001 ctatacgatc ttgctgatag acacgaagag aatcaataga tagttctagc tggttgccaa
    60061 agctgacttg tagatttgtt atatttactg ctaaattttc catatgtttt acactcctat
    60121 ttcatgtaaa acaacaatta tcgatactaa aaaagagcag aaaaatctgt ttgcaaaaaa
    60181 actgcatcac atcttttcct actctgaacg aaataactat gactaaatca ccaaatctgt
    60241 catagctttc acctattcta ctgtcgttcg aaaaaatgga catactccat ccatgaaatt
    60301 gttgtttata catgtctttt gaatttattt agttgttatt caaaagttcg aaacgtaatt
    60361 tcatcgatgc agtcattttt ccgacctcct tttttattag gttaccacac acgattcaaa
    60421 aaaagcaata gctactgaat agtaactgaa aaccttttat tcgaacatag tgatcttttc
    60481 tggtgctaaa cgaacagact cgtaaccttc ttctaccgct tttcctattg ataaaataat
    60541 aactggaaca taacggtctt tatccaaacc aaatgcctct gccaactgat ctgcttcgaa
    60601 tccaccaatt ggatttgttt catagccatg atcacgcgca actaacatga attgcatagc
    60661 cgctaagcta gaatcgactt tgactacatc gttcatttct tctcttgaaa aactcttgta
    60721 ataaggaatg atcgcagcta attgttgatc tctgacttct tttggcatct tccctgattc
    60781 gtaagcttgg ttgtagattt cttcgccata ttcgtaacat tgcatatcgc caaaaatcat
    60841 gaccattgca gaagaagtat cattttgtct cgtattgaaa cggatcaaag gacgcaagat
    60901 ttcttttgct tcctcgcttt cagcgaccac aaagcgccat ggtttcatat tgacagaaga
    60961 aggtgcagtc gtcgcttctt tgatcatttc cagcatttct tcgtgtggga ttttgtatgt
    61021 ttcatcatat acgcgaacgg atcttctacc agtcataatt gttgaaaaat catttttttg
    61081 ttccattatt attaacctct ttcgtttctg ttgttatatt gcaaagttgg gtattcaatt
    61141 tatctaaaag tgttagaaat tgtttcattt ctacatcgct gaaagccggg gatagcacgg
    61201 aacctgtatc tttatggtcc atttcacaat gcttgatttt cttctgggct ttttctgtta
    61261 gcgctacata cacttcccgg ttgttctgag gatttctctg acgcgaaaca tagccatttg
    61321 cttccaatac cttcagatga cgagtaactg ctccttgatc aatctgcaac ttttcttgca
    61381 aactgctttg tagcaatgga ttttcttctt tcagtctcat catgatctcg tatctagtaa
    61441 gacttatacc gatattttct tcaaagatct ggacgatttt ttgatcggct aatttgattt
    61501 gatataaaag gtgactaatc tcttctaaag acataatttc ctcctttcta ataattgact
    61561 cgtcaacgat tgacttgtca ataatagaat aaaaaaagaa aaaagtcaaa gaatcagctg
    61621 tgtaataaaa aaaacgctct caatagaaaa gtatagagaa aagaaatttt ttgtagaatg
    61681 aacggaaaaa atgataaaga aagcacaacg ctaaaaccaa gattattgat tcttatcaaa
    61741 ctatagaaga tagctcttct gcagtagata attttacacc gccaaaaatt tccgaaatcg
    61801 ccttttgcaa gaatcccgtc gaatattaga aattggatca gtatgcttaa acagtaataa
    61861 aaaagttatg acaagatgtt gtcacaacct tttttgagta aacggtgttc aaaaacttgc
    61921 atctgcggta ataagttcaa ccaaacaaaa aacatgaaaa tctgtttttg tttggctgtt
    61981 cttactactt gatgcagggc agctttttca ctacctcttt ttaataacca taaaatccta
    62041 ttccttcata tctccagccc atcggtgtta gccaatctct ttccttagca ctcaaggtat
    62101 agtgatgggt accagttttt tcatttggat taaatagtcg ataaattggc ttggaaccac
    62161 cagaataaaa acttagacct tcataacgcc aaccgatttt tgttaaagag ttgatctcag
    62221 attgtgccat tgtgtaatga tggtctccac tgtaaggatt gtataaacgg tagacaggtt
    62281 gtccgctgtt tggtgcttgc caagcaatcc cttcatattc ccagcctaca gttggcagat
    62341 aatttttttc tccggcattc aatgtatata aatgttctcc tgtatgacgg ttatacagac
    62401 gatacatcgg agaagttgaa gttggtgctg tatcatactg tgtcagatta taggtttcga
    62461 ttacattgtt caatgtagaa ccataattag gcgcagtggc ataacgacct gttagccaag
    62521 ccgtagcatc tttgtaagag ttcgtattgc ttttccatgc accggaatag tagtaaacgc
    62581 ctggctgaaa agaagtcgtc ttcaataccg ttacgttatc ttgcaatgat tctttgtacg
    62641 aaggatattt tctaaaagcg gcattcaccg taatccattg cccattcaca tattccgaag
    62701 taggcatcgt aacagattgg ccattatagc ttcctttaat cccaaataga ttgtaattag
    62761 gggcagaagc caaagtactg ttcccccagc cactttcaac gatggcttga gcaatcatga
    62821 ctgatgcata taagtcattg gcacttgcca aactttgtgc agttgaggca atactatcaa
    62881 tgaacgcttg ttgagaatta gcagatgagc gagcataaaa agcatagcca gtatagtttt
    62941 cgaattcaga caaatctgct tgatgggtat gtgtcaatgt ttgcccatct gtcaattggt
    63001 tcgtgatttc ttctgcattc tctggattgt tctgagcttc tgctgatgta ctgtcttcgg
    63061 tttgtgtttg ttctgttgtt tcagttgttg gttcttcggt tgaaattgta ttttctgaga
    63121 cagtagctga ctgcaaagta ctttctgtat cgttttcaat tcctgtttct gaagaactcg
    63181 atgtctgagt tgcgacagtt tctgtcgatt cttcagctag cactgttgtg ttggcaactg
    63241 ctagatttcc taaaagaata acgctaaata ataaattctt tgctttcatc ttttttctcc
    63301 tttgaattat gaaacttttc ctaaataaca gtgtaactaa aaaagtaaaa gcaagtcaat
    63361 gtccatattt aaataacatt tgtttctttt taataaattt gctttttctg cataaaaaga
    63421 cgtaaatgaa gaatattctt ctccattcac gccttaaatt gatggtcgtt tgaataacta
    63481 tttaacaagt aattctctct ggatattatc cgttatggat tatacttcct gtgtcgtcgg
    63541 acggataatc atgttgctga cagacatccg gtctggcgtt tctatcgcaa atgctacagc
    63601 agaagctata tcttcagatg ttaatcccca ttctttttgc gcttcatgaa gttcaagagc
    63661 agcctttttg tcgctgatgg tttgatataa ttcagtttga acagctcctg gagagatgat
    63721 cgtagatttg atgttatttt gccgttgctc ttgacgtaat ccttccatga ttgcacggac
    63781 agcaaatttt gttccgcaat aaacggcgga atcaggataa acaacatgtc ccgccacaga
    63841 atcagttgaa atgatatgcc cagatttttg tttttccatg attggaagta cggcggaaat
    63901 tccatttaac acacccatga tgttgatatc aagcatattt tgccattcat cacggtgacc
    63961 ttcaactaat ggagcggttg gcatgattcc tgcattattg tacaatacat cgattcgacc
    64021 gaacttttcc atcgctaaat cgataactgc ttggacttgt gcaaaatctc ttacatctgc
    64081 tgtttgaata tatagctcag cttctggtaa agattctttt attgctttta ggcgatcttc
    64141 tcggcgtgca gctataacta gtttagcccc tttttctgct aatagcttcg ttgttgcttc
    64201 accgattccg cttgaagcgc ccatgatgac aatcactttt tctgataaat cattcattct
    64261 attctcctcc tgttttgaaa aatctcttgc ttatactcac tatctcttat ttcatcttac
    64321 tgttcaaata atccgttcga caggtttgac gattttggca gggattcctg caacgatggt
    64381 attgtctggg acatctttcg taacagttgc attcgctgca acaatggcat tctcgccaat
    64441 cgttacgcct ggcagaatag ttgctcctgc tccgatccaa gcatttttct tgatgtggat
    64501 tggctttact gacaagcctc ttcgttcttt tggatcggtt agatggttca ccgtgatgag
    64561 gttgacacga ggaccaatca atactgaatc ttctaaacag atgccaccta agtcaacgaa
    64621 catcacttga cgattgataa agacattttt ccctatacta atatgtttgc cgaaatctgt
    64681 ataaaaaggc agcagaacag tcaccgtatc atctactttg tcactaatga tattttctag
    64741 ccgtttgcgg atatctgctg gttcatggta cccagtattc agcgctgcta aaggctcttc
    64801 gttttccgct tggatctgat ggatcacttc aaagagcgga tccgttactc gaatctcttt
    64861 attgacgatt tgtttttcga tgaggcttgt cattttgctc cctcctttta tccttacttt
    64921 ataacggacg gcttatgatg tctaatactt ataaaacata cttaactatt ccttttaact
    64981 atacttagtg gtatgctttt ttaaaaacag gagggaaaaa atggatattc gtatactgac
    65041 gtatttttta gcagtagcta gagaaaaaaa tatcagccga gcagcaaaat ctctgcatat
    65101 cacgcaacct actctctcaa aacaactgaa agatttagaa gaagaacttg gtgtgacact
    65161 tttcactcga ggctcccgag agatacagtt gacggattct ggtcgatatc tttattcaaa
    65221 aggaaaagaa atcttgtcgt tggtagaaaa aacggcgaac aatttaacaa atgacgcaat
    65281 catctctgga gaaatctaca ttggcggagg cgaaactaaa gcaatctctt tcatttctga
    65341 tagccttcat tcgttgatca aggcgcatcc tgatatccag tttcatttat atagcgggaa
    65401 tgcagatgat atcatagaca aactggatag cggattactt gattttggac tcgtaatcga
    65461 accgacaaac aaacaaaaat accagtcatt tcgactgcca gcccaagatc gttggggact
    65521 tttgatacat cggaatcatc ctttagcaaa gcaaacagtc atccatccgc aggaactgaa
    65581 aactgttcct ttgatcattt cccggcaaac gtcagtggac agtcaactag ctgaatggct
    65641 aggtttcagc atagatcagt tatcgatcgt cggaacatat aacttattgt acaatgcttc
    65701 tttgatggtc gataacggga cttttggtgc attagctcta gatgggatca tcaatactta
    65761 tgggacggaa aaagtattca tcccactcga tccgccatta caagcttcac tgaatctcat
    65821 ttggaaaaaa gaccagcctc tttctcctgc tgctcgtaaa tttttagatg tcctaacgga
    65881 gaaatacagt taagtagagt ttttttcctt cgctttcagc tttttaacaa cgaataagtt
    65941 aagcaaaaga tccaatgatt aaataacata agtttcttaa tttgttcctt ccttttattt
    66001 ctgataattc cagtaaatta ctataattat aaaaaaagaa ttgacaaaac ataactgtct
    66061 atataaaatt gattacgtta acaataattc gtttcatgtg actagatcat actaggcatg
    66121 aaaaatctct gaggaacatg gtttccctag gaggtttttc gtgtctattt ttgtttggcc
    66181 gcaatcaact ggtctagcaa acgtgaaaac caaatcttca aaaagggtgc gcgcatgaaa
    66241 atcaaaaaga tctttaatca aaatgcagta ttggtagatg acggtggaca ggaaaaagta
    66301 gctattggaa aagggattgg atttgacaga aaaagaaatg atttgatttt tgatcgtgat
    66361 gtcgaacgga tatttgtcat ggaaccagaa ggtcaaatca agttgcaaaa tttacttaat
    66421 cagattgatg aacgcttttt atttgcagca gaaacgatca ttgatcatgc ggaaactgtt
    66481 ttgatggaaa agttgaatga acatgtattg atcgctttga ccgaccacat tgctttttct
    66541 gcggagaaca ttaataacgg tatcgtcatc cgcaacaaac ttttaagaga aatcgaagtg
    66601 ctttacagtg atgaattcag tattgctcaa tgggcagtag agtatctgac aaaagagctt
    66661 gggattccat atacttatga cgaagcagga tatatcgcaa tccatattca cagcggacga
    66721 agcggtcgga acaataacca tcgcagtatc cgtgaagtga cgattgtatc tgacatcatc
    66781 catttagtgg aatcagaatt ggaaacagat atccattcag aaccattttc actgaattat
    66841 tcaagactgg tgaatcattt acgactgctt ctacaacgaa cccatgcgca acaatatgct
    66901 gttttagaca cggaaatcgt agaaatggtc aaacgaaaat acccagaaag ctataagatt
    66961 tctaaaaaaa tccgtgtgtt gctgaccaaa gaataccagc tcgcgatcac gaaagaagaa
    67021 ctgggttact tggccatcca tatcgagcgt ttaagaagcg caatcgtaca aacaaatgtt
    67081 aacaatcatg aggaggaaaa aaattgaaag catatctaca acgaatggga cgttcccttc
    67141 aacttccagt tgcggtctta cctgctgctg ctttactagt agggatcgga aactggtggg
    67201 catcttatag taacgacatt gtcgctcatt ttttacaagc tggcggtaac gcagttttag
    67261 gtcaattacc tttgctgttt gccgttgggt tagcactagg gatgtcagtg gacaaatcag
    67321 gtgctgctgc cttggcaggt ttggtcgcat ttgaagttcc agtaaatgtt ttaaaaactg
    67381 attcagtagc tactttattg aatatcaaac cagaatcagt tgatccatct tttgctcaga
    67441 tcagtaacgt atttattggt attattgccg gattgattgc ggcagctctt tataatcgtt
    67501 tccacgaagc aaaattaccg atggctttat ctttctttag cggcaagcgt ctagtgccaa
    67561 tcttggctgc ctttgtcatg ttgctgatca gtgcagtgct actgctcgta tggcctccgg
    67621 tttactctgc tttagtttct tttgctaaat tcattttgag tttaggctgg ggtggtgcag
    67681 gtctttatgg cttcttcaac cgtttactga tccctacagg attgcatcaa gcaatgaact
    67741 ccgtgttctg gtttgacgta gcaggaatca atgatattgg taaatttttg gcttctgaag
    67801 gaacaaaagg cgtaacagga atgtatcaag ctggattttt cccaatcatg atgttcgggc
    67861 ttccagcagg agcatatgct atttacagaa atgcacgtcc agaaaacaaa gcaaaaacag
    67921 cttccttgat gttagcagca gcttttgctt cattctttac tggtgtaaca gaaccacttg
    67981 aattctcatt tatgttcgtt gcttggccat tatatgtctt gcatgcaatt ttcactggga
    68041 tttctttagc agtgagtgca ttcttccatt ggacagcagg atttgccttt agtgccggat
    68101 ttgtcgatta cttcctatct ttgaaaaatc cgattgcgaa tcagccattg atgttgatcg
    68161 tccaaggatt agtaacagca gtgatttact actttggctt taactttgct atcaaaaaat
    68221 tccatctgat gactcctggc cgcgaggaag cagatctttc agatgacgat actgcaacga
    68281 ctaattcaga caataaatat gcggcacaag caagcaaaat ctacgctgca ttaggcggag
    68341 ccgacaatgt aacttcgatc gataactgta ctacacgcct tcgtttgcaa gtcaaagata
    68401 caggcctgat cgatcaaaat aaaatcaaag ccactggcgt acctggtatg aagatcatcg
    68461 acggaaaaaa tgcgcaagtc atcgtaggta cagaagtaca attcgttgca gatgagatgg
    68521 caaaactaca tggtggtgct gcaacacgac ctgcacaaac aaacaccgtg gttaaaacag
    68581 aaacatttgc cggtggaacg atcgaacaag atatttacgc tatcgcaaat gggaaactga
    68641 ttccaatcac tgaagtttca gatgatgtat tcgcggaaaa aatgatgggt gacggctatg
    68701 ctgtattacc agaaaatgga gaaatcttct ctccaatcgc tggtacgatc acaaacattt
    68761 tcccaacgaa acatgctgtc ggaatccaaa cagatgctgg tatcgaagtc ttgcttcata
    68821 tgggcatcaa cactgttgac ttaaaaggcg aaccattcac tttatatgta aaagaaggtc
    68881 aaaaagtcgc aagaggtcaa ttgattgctt tagttgatct tgccgctatt caatctgcag
    68941 gcaaaaacac ggatatggtc gttgtattca caaatggcga caaagtccaa agcttagaaa
    69001 tcgaacccgc acgtgatgta aaagcaaatg ataaaatcgg ctctgtttcc aacaaagcct
    69061 gagccatcgt cttccccaga cttttttatc gataaacaaa caggagctga gacaaaaatc
    69121 ttgtctcagc tcctttttcc gaataaaaac ggcgttctcc tgccaactcc gcggtaataa
    69181 gtccagccaa acgtaacata tgaagagcta ttttttattt gactcttctt attacttgat
    69241 gcagaacagc ttttttacaa cctctgataa acggtgttca aaaaccagtt tatcggtatg
    69301 aagtcaaatt tatgcaaaaa tgtggaaagc cattttcaca aaatttttct tcatactcaa
    69361 aactaatcgg ctttttcaca acctctttat acattattcc tgatccaata tttcttttaa
    69421 tgctgcttca agagaagtta atggttttcc caatactttt tctaaatcat cagaggaaat
    69481 agctaactga tcctttttaa tatcatgttg gatcgctaaa aacatgtcag ctgcttcttg
    69541 agggaatccg gcttctttta gattttcgac aaacgctgca tcacttgctt caataatttc
    69601 taacttttta cctgtcgcac gctctaatgc cttggctaat tcttcatagt cagttagatt
    69661 gccggataat tctaagattt ctggagagtc actttctact agtacttttg ctgcagcttc
    69721 tgcatattca cgtttcaatg cccaacctgt ttttccattt cctgcagcat aaacgaattg
    69781 accagttttt aaagcctgcc caatgatagg taattcattc tctacatacc aattattccg
    69841 taaaaatgta tgggaaatac ctgaatcctt aatcattttt tcagtgaatt ggtgatctgg
    69901 cgctaataca ctgatcgagt gatcggcatc tgcaaaactt gtataagcga tataagatac
    69961 cccagctgct tgtgctgcct tcactacatt cttatgttcg gcttgacgat ttcctggaac
    70021 gccagagaca aaaagcaatc gatctattcc tttcaacgct tctttcattg agtctaaatc
    70081 atcataatca ccaatacgta tattaaatcc agcttctttc agtgcttctc ctttttcttc
    70141 actacgtact agtacataga tttcattttg tggaaccatc ttttttaaga attccagcgc
    70201 ataaccacca aaacctccag ttgctcctgt tactaaataa tgcatatttg ccactcccta
    70261 ttctttttat ttgttaagat ttacagctgt acatttataa attacacctt tatcataaag
    70321 agtgtggtaa gataagtcaa gcaaaaaaaa tgaaaggatg acaactgatg aagtattctc
    70381 tgcaatttag tgatgcaatc catgtacttg cctatattga aatgtttcaa gatacccgat
    70441 cactttctag tgagatgatt gccagtagta tcgaaacaaa tgcagcaaat gtacgtaaaa
    70501 tcatgagtca gctcaaaaaa tccggtttga tctttacaaa aaccggaaaa ccgcagcctt
    70561 cccttgccaa aagtccagat cagatttctt tactagatgt ctatcgcagc atcgaaggta
    70621 atacacagct tatccaagtc gatccaaaaa caaatccaaa ttgcgtcgtt ggtgcgaata
    70681 tccaagaagc tttagaagaa agctacgctc ggctgcagaa aaaggcagaa gaagaaatgg
    70741 ctaagatcac acttgatagt ctgatacata aaatagccgt tttggaaaaa gaaaaaagac
    70801 cagaaaacac aggcctcgta gagagatttt tataattctc tctactgtgc ctgcattttt
    70861 ctgatcggaa tcgtctacat aaattctttt attctccggg ggacaaaagc cttgtcatgc
    70921 ccctttttcc tctctaatgc tcaggtcaaa gcgctgaagt catgacgtct tgataaacgg
    70981 tgttcaagta gctgaccctc ggcattagtt ctgaaaaatg caaaatatgg aaagctattt
    71041 cccatttttc ctctctaatg ctcaggtcaa agcgctactt tcacgacctc tatattatca
    71101 tggtttattg actaccggta tccagatttc tcccatatat ttcccgttgg taactcccat
    71161 ttcgactaca gcatttggac ccccaacata ggcgtaatct tctacttctc ttaaaacatg
    71221 cccaaaggcc gtattcgtca aatcatttct taattcttca ggcgattctg ctaaagcgat
    71281 tacaacaaga tacgttcctt ttgggaatgg gatgattcgg gtagtgtttg gaacatcctg
    71341 actcgtttga acaccgacat agtacatcat tttcccgtta tagggttcgt tgactgtaaa
    71401 gaaataatga ttttcagcag cttgtttcaa tgcatctatt gttccattac cgataacttt
    71461 ttgctcaaat gcttgtttct ctgcagccaa accgacaaaa tccgtattgc tactcttcaa
    71521 ttccacacca atacccgtca ccgtaaaatc tggtttttct tcgatcctat actttgccat
    71581 ttctcccacc ctttctatta tattaagttc atcttacata aaattaaagg gaaatgacac
    71641 gattacgctc ttttttctag ggatattttt attttttaac tatttttttg ctttcactgc
    71701 aatccaaatc tcactgtaaa cattactgaa atcctctccc cattttgtaa aagagatctc
    71761 gggagcttcg actaactcat aatctgaaga aggaagccat tctgcataga ttttccccca
    71821 agtatcttgt aaagtttggg gaaatggccc tttattagga aaaatggccc aagtgtgttc
    71881 ttctatagca agcatttcta aatcagcgta cggattttct tttgtcgtag caaagccaat
    71941 catgtgcatc aaactgccct tttcttccaa gcgggctcca tcaaatccat aagaaacgtt
    72001 gattacttga tttggatata aatctcctaa cttatgcatc tcttcccttt gagtctccgt
    72061 gatcgtctgc gctaactttt gtatttcttg attgactcct tcaaatttga caggaacttt
    72121 tttcgccaca cctgccacat aaaactgttc tttcttttcg atacgaaatt ccatcgattt
    72181 tcctcctctg acatcaataa aaaatgtcaa gcgtggaaaa gatttttgta tgccgtatct
    72241 gctgatttct gaaggcagat atcctgacca atcacgaaaa gctcttgaaa aaccttcgac
    72301 tgtttcatat ccatatctaa acgccgtttc tgtcactctt gatccatcta ggagatcgcg
    72361 attagccaaa gccaatctac ggtttttgat atagtccatt agcgacatcc ctgcaataaa
    72421 cgtaaagatg cgttttaatt gatattcaga gattcctgta ttttcggcta ttattttata
    72481 ggaaagtcct tctgtcaaat gttcttcgat gtaatcgatc aattggttca gatctttaag
    72541 catatttatc ttcctccttg cttgcctttt tatcatatta tcaaagaaag tcaattactt
    72601 gatgaatcag gaaccaattt agtcagatgt agaaaatgtt gtatggatct aaagaaaatt
    72661 ctcaagcagc gtttcgtaac ggataattgg tattatctgc ctatctatgt tttaccttta
    72721 gaaaaataaa ttttggggaa gacacattct aagtaaacaa agcggtaaaa atatctttta
    72781 ttcccttagt taatccgctt actacctact gtacaaagca aattgttgtt caaactgctg
    72841 atcagaacgc tgcttggatt tttctttgcg atacatcata cctcttttat caattggaac
    72901 aattatttat ttctaacaaa atcacttcat ttttgtcaga taaataaaaa acaaaaaaag
    72961 ttccatcttt aaaacacgct attcttttac tttttctcac attctctaag aaaagaaaag
    73021 gagaatgaat ttttgacaat tcgagcaaaa gtgattatca aatatgtaaa atcagctact
    73081 tttttcttaa acgtttcttt atactaaata taaataagtg tttcatgaaa ggagaactag
    73141 atgaataatt ggcttgagta ttttcctgaa aacgttttgg aacgcggtta cagctatcat
    73201 ctgcacggtt ttgtccgtca tttgaactat acaagcaagt acttgtccgc aacagtttct
    73261 ggcacggaag attataaggt agtgatcact tgggatgaaa agaccaacat gacttgtgat
    73321 tgtctatatg ccatagaagg aaaaaaatgc aaacacatgg ctgctgtctt attcgcttac
    73381 gaagaacgtc caataaaaaa atccaactac tcactttccg aactctcgtc ccttgtttcc
    73441 tccgctagtt cctctcttgt acgggagctt ttaacagaga ttcttataga acatccgcaa
    73501 tttatcgaac gcttcaaagt taagatgcca tttcatgcaa taaattattc agataaatta
    73561 acaactatca tccataaata cgatcatatt atcaagaaaa acaaaaacag gaaaacagcg
    73621 aagttcatca tggagatgcg aaagttcatc caagaagcag ttgaatcgct cattcagcaa
    73681 aatgcctatc ttcccgcatt cgaattgatc aatgaagtga ttgctactct cgaaacattc
    73741 tattgggagc ctgaggatga acgaaccctt cttctgatag aggactgtta ttatttatgg
    73801 aaagaattat tagcagaagc acctcatgca gaaaaaaggc aaatgttctc ttggttcgtc
    73861 tgccaagtcg atcatactga cgcctcttat tcaaaacgct actccataaa aatcctgaaa
    73921 gaagactttc gggaaaaaga attttctaac caaaagaaaa aaatagataa aaaaactaaa
    73981 gaaacggtaa agaaagacga tttcaatgaa aaatagcaag taaacgataa caaccatcct
    74041 aaatccacaa gaaatacagc agaccttgct ttaaaaacac gaatcatgca aaggatgaag
    74101 taaagaagac ttaacgcgta cccaatatta gtcatttgac tattaggtac gcgttttgtt
    74161 ttataagtca tgacaaattt ccttcgttgc tgggtagatt ttccggcatt gttgatagat
    74221 tttatgatac ttttctacat tttgtaagag aggttccact gcatctgtat attggataaa
    74281 attctgacaa caactttcag gtgtgtcgaa ccactctaat ctttaaagat aaatattaaa
    74341 ataacgatta ataatattaa cagtctttat ttttcaccac caaaaaccta tctttgcata
    74401 tactaaatag acgtatatac acagataggt ttgtcttgtg aaaaataatg attatcctta
    74461 ccaaaaaatg tttgtttttc tacatgttcg tacttatcaa aaaatatgat ccttattgaa
    74521 attactggct atttatattc caacgacttc ttgtgttaat ttttgttatc tcatagtaaa
    74581 ttatgtttca ttttcactta atttagttgt cacgtgttcg tcaattcgta aaaacggtaa
    74641 atatataaac acacttgcgg ctataattaa tatttgtaaa acagctgctc gccagtctcc
    74701 ggctgttgct aaaaatcccg atataactgg tggcgtagtc caaggaattt gcactactac
    74761 atgattaatt aatcccacag cagttgcaaa atatgctact gtcaaagaaa aaatcggtgc
    74821 aagcacaaag ggaataatca gactgatatt aaatacaata ggcaatccaa aaataatagg
    74881 ttcgcttata ttgaatatag cgggagttac cgataattta gcaaagtcct tataatcttt
    74941 tctacgactg aagataaata ttgcaatcaa taaagcaatc gtatttcccg atccacccat
    75001 taccgcaaag gtatctttaa aggccatatt gataatatgt ggaatttgct ctttgtttgc
    75061 ataagctgcc atattttctt gcatattctg aatcaaaaac ggatctaaca atgaacctga
    75121 tattactgct tgatggatac caaatccaaa aaatagatta gcaatagatg taattaacaa
    75181 aaatcctggt aaaccagttg taattttact taatggctct gtaactatcg tggtaattag
    75241 cttatttata tccatattaa acaattgaat gattataaat gacaataaag caaacgaggt
    75301 aatcgtaata atgattggga ttaatacatt aaaagacttt aaaacagcgg gaggaatatt
    75361 tccggatagc tgaatctgta gtttcttatt attagaaagt ttaataaata attctgtagc
    75421 cgctaatcca acaaatatac ctacaaacat tcctgaagct cctgtatagg atataggtat
    75481 cacacccgtc acttcaacag ctttatccgc attttcagga gtaaacatca tctgcatagg
    75541 tgttaataca acaaatgtcg aaatagcaac taataccgct gcaatatgat ttgtataatt
    75601 tctgcttgca cacatatgat aagatactgc tgctacaact aataatgtag ttatgcttaa
    75661 tgtaccattg gcaattgaag taccaatttg ttgtaacgtg gtcaatgtac tagtatcgac
    75721 aatttccccc atgaatcctg ttggttctaa gatcactgaa ttaataagtg tcacaaatcc
    75781 tgctaacatc ataaatggca taaatgtagc aaacgcatct cgcaaagttc ttaaatggat
    75841 ctgattcccc aacttagtcg caactatacc aaatttttca aatacaatgt ccttcctgct
    75901 acttttgccc atattttttc tcctttatgc ttattgtaat cgattacttt ttccacccaa
    75961 ataatacatc acttatcaaa aaaagtaaat acttttaatt aaatatatat atctttttta
    76021 gtataaaaaa ataagctctg aaaaaataat tttcccgagc ttatttttca acaaaaacag
    76081 cttcaaaaac aaagtcttga tataaatgtc tcgataccga atactcgaaa ggtttaccag
    76141 acgatagagc aacaactttg tctatctcaa tcataaattc acctggatct atttttaata
    76201 tttttgcgtc aaattcattc gcagtatctc ctttgatacg tatgtgcgaa gtctttattt
    76261 ccagacccag ttcatttgtg atataagcat atacagattt ctttaaatgt tttggttcca
    76321 agcctggtat gactgctaat ggcatgaatg tttgctcaat cgagtatggt tgacaatcaa
    76381 taaaacggct tcgtacaata ttatatacat agtcttttac actgatactt aatttatcag
    76441 ctactttttt cgatggaagt tcaattgaga aagtatggat ttctgaatct acgtgttctt
    76501 caccaaccac gctaaacaaa ccttcgtttg gaccaagaac tcgtgagtta tcaattggtg
    76561 ttctgacgac ttcagtccca tacccacttc tacttcgcaa aactccttcg gaaacaagta
    76621 agtctacgcc tttctttact gttaacttgc ttgtatgata aataactgcc aattcatctc
    76681 ctgtaggaag tttctcacca attttatact ctccatttac aatttttttc tttatatcta
    76741 agtaaatttc catatacttc gcaatttttt tcaatggtga ccctccaatc aaaaacatat
    76801 cttcatctat actttaacat aaataaaccg ataaaatcca catcaaaatt atacacacaa
    76861 taaaaaagat atatatattt aaacaaaact atttacttta agttgtaagc ggtgttatca
    76921 ttaagtggaa acaggaggta aaaaaattat gacaactatg aaaaagctaa cttttccaga
    76981 tgatttttgg tggggttccg cttggtcagc tgagcaagca gaaggaaaag gagaaacagg
    77041 aaaagcagag actatctggg atcgctggtt taaagaacaa ccttaccggt tttatcaacg
    77101 aatcgattcc tctattacaa ccgatcacat ccatcaatat aaagaagata tagaactaat
    77161 gaaaaaaact gggcataact cctttcgcgt ttctatttct tgggcacgaa tgtttccaaa
    77221 tggcggtacc ggaaaagtaa atcccaaagc catttctttc tatcgaaaat tattttccga
    77281 aatgaataat aacggaatca aagtatttgc caacttatat cattttgaca tgcctgctac
    77341 tcttcaagat aaaggaggat gggaatcacg tgaagtagtt gatgcttatg ttcattacgc
    77401 tgaaacttgt tttaaagaat ttggtgactt agtttgtcat tggtttacct tcaatgaacc
    77461 acttgggcct attttaggta cttatcttga agattttcat tatccaaacc tcattgactt
    77521 taaacgcgga gcgcaagcag cattcttcac tatacttgca cacgcaaaag caatacaagt
    77581 atttaaagaa ctagctcttc ctagtaaaat aggcgttatt ctaaatttga gtcctacttt
    77641 tcctcgtagt caaaatcctg ctgatgtgaa agcagcagaa atcgctgatt tattttatac
    77701 gcggagcttt ttagatccta tggttaaagg gaatttttct aaaaagctta tcctgttatt
    77761 acaagaatat aatcagcttc ctgaagatta tacgaaagaa gatcttgtat gtatctacga
    77821 aaataccgct caaattcttg gactaaacta ttacgagcca cgtcgcgtca aatctcgttc
    77881 ttctatggtg gatacatcta gtccattttt accagagtgg tttttcgaac cacatatcat
    77941 gcctggacga cgaatgaacg aataccgggg atgggaaatt tacgaaaaag gaatttatga
    78001 tttgtgcatg gatatcaaga accattatgg aaacatcgaa gcatttatct cggagaacgg
    78061 aatgggcgtt gcggatgaag aacgtttcat ggatgataca gggcaaataa ttgatgatta
    78121 tcggattgag tatatcaaag atcatcttgc ttacttatgg aaggcaataa atgaaggatg
    78181 taacattaag gggtatcatc tttggacatt tattgattgc tggtcatgga tcaacgccta
    78241 taaaaaccga tatgggctgg tttcactcga ccttactact caaaaaagaa caattaaaaa
    78301 aagtggcgaa ttttacaagc aattaagtga tacaaatgga tttagatacg atgtagactt
    78361 gttagttgaa taatattcta aaattccact tgaagtgaac acattagaaa acaagaataa
    78421 tgagaaatac caataacaaa tactttttct tcatacttca tttatacttg tcagtataag
    78481 agactgtgac aaatgtagtg atcctcagaa gttaggtctg gaaatctaac ttgagaagat
    78541 ttttttaaac tacgtccagt cttttttatt tgtttaaaat tgaagttgac aagtcttcat
    78601 taaaaattta gaatattcac aagtttgacg acaattatga aaatttatgt cgtgctaaag
    78661 gagttttgtt attggatgaa aagttagata taaaaactgc gatcaaagac acgttaccta
    78721 ccgtttttgg ttatatcggt attggacttg catttggtat cgttgggaaa gctgccgggt
    78781 ttcatccgct ggtcgtcacg ttgatgtccc tgctgatcta tgctggttct gcccaattta
    78841 tcacggtcag catgcttgct agccatagtc cactgctctc catcgttctc tcgacctttc
    78901 tagtcaattc ccgaatgatt ctgatgagta tgacgattgc tccttatttc aagaaaaatc
    78961 ggctgcttca aaatctgctg attggcacat tgctgacaga tgaaagtttc gcactgggaa
    79021 tgaataaatt gaactatact ggacaaaagt taaactttcg ttggatgaat acagctaatt
    79081 ggatttctta tttgacgtgg gtgggttctt ctcttgttgg cgcactttta gggaatttta
    79141 ttactgatcc gaaaaagttt ggtttggatt tcgccatcgt cgctatgttt atcgggttac
    79201 tttatcttca agtcatttct gatagaaaca cctctaaacg attacagttg atcctgattg
    79261 gtctcacttt gattctggta tatgtcggac tgatttttat cccaagtaac ttagtgattt
    79321 tagttgtaac actgattggg tgcggattgg gggtgtggat caaacatgcc ttcttttgag
    79381 tttacattgc tgactatttt aggttgtact ttagcaactt ggctttctag gatcctacca
    79441 tttgtcttac tgaaaaaatt cgatttgccg caaccgttgc ttgagtattt aagttttgtc
    79501 ccgatcgtca ttatgtctgc tttatggttc agcagtctat ttacccaaaa tatcggacat
    79561 ctgccgcaga tcaatctcga aaatgctttg gcttcagttc ctacactttt agctgctatt
    79621 ctttcaaaaa gcttattggt gatcgtcttg gtaggaattc tttccctttc gttgattcgc
    79681 ttattataaa taaaaaaaca agagcttatg gcaaattact gtcatgcgct cttgttttta
    79741 tcaaagtcaa ataagaaaaa aatcggcgta ttcttgctta tccgttgaac ggaccactaa
    79801 caacgacttt tcctaatata tgtcctgttt ctacgtcttt ggttgcttgt ttcaagttct
    79861 tcgcattcat cccatctgaa tagaccttgc tcaatgtact gcggataatc ccttcatttg
    79921 ctaaagcagc aatgtgcgct aaagcttctc cttgcgtttc gatttcatag ttatagtctg
    79981 ttttagcgaa catatactcc cagtcgaagc tgatagattg gtttttccaa acacctatat
    80041 ctaacggctc tttgatccct acgatcgttc ccacatgtcc aaatggtcgg acaaggtgtt
    80101 tgatttgatc aaagtagcgg gtaatatcga ataatacagc gacatactct acttgatcga
    80161 ttcctaattc acgaaaactt ttacttaagt cgtgatgata atcgattgga tagtctacac
    80221 ctgttttttt cagccattca aaattcttcg gacttgcagt cgcgtagact tctaggccag
    80281 cccaatgcgc tagttgattc aaaatcgaac cgacgccccc agctccgttg atcactaaga
    80341 tttttttccc gcggttggca ttttcttctg gagtcagacc aaatttttca aataacaatt
    80401 cataagcggt caatgaggtc aacggcaagg ctgcggcttc ttcatctgaa agattttttg
    80461 gtgcaagagc gacaatacgt tcgtcaacca gttggtattc ttgattgctt cctgctcttg
    80521 tcgttgtacc tgcgtaaaaa acgcgatcgc cgacagaaaa tttttgcact tcatcaccta
    80581 cagcaacaac tttcccgact ccatcaaacc ctaagatacg taaagcattt cttatcccgt
    80641 tatcttggcg aagtttcgta tcgacaggat taacagatac tgcgttgact tttaccagaa
    80701 gatcccgtga actgggtaca ggtatctgtt ctttttcatc aataaagctt tttggatcat
    80761 cgatcgacaa cccttcataa aaaccgacta ccttcattaa ttccttttct gacatacgaa
    80821 ttcctcctta gcttcatcaa gttggagcat ccatacagtt ttcatttcaa tatatatagt
    80881 atgctatttg ttccactttt attcatcata attattctct tacttaaagt aaactatttg
    80941 cacttttttg gttaaaaaag aggttgcgac aagacttttg tcacaacctc ttttaaacgg
    81001 tgttcaatca actgaccctc ggtattcgct caaaaaacga caaaatatga ggagctattt
    81061 ttgtttggct gttcttatta cttgatgcag gacagctttt tcacgacctc taattcacgg
    81121 tgttcaagca agaaatcatt gttcactgaa aagcgttgga tgttcttttt caaaggtgtc
    81181 taagatctct cgtacttcat cagtagattt cgtattcatc aactgaactc gcaagtcatt
    81241 tgctcctgga aatcctttga tatagatttt aaagaaacga tgtagtcctg tgatggaacg
    81301 cgggatgatt tctgaataat gatcttgcag atctagttgc agacgaagta gtccgatcag
    81361 ttctttttct gtatgttccc tcggttcttt ttcaaatgca taaggattct tgaaaatccc
    81421 ccggccaatc atgatgccat ctacgccata tttttcggcc aattcttctc ctgtctggcg
    81481 atctgggata tctccgttga tcgtgatcag tgtttgcgga gcgatttggt cacgtaaagc
    81541 aatgatttta gggatgactt cccaatgtgc atctacttta ctcatctctt tacgcgtacg
    81601 caaatggaca gaaagattgg ctatatcttg atgaagtagg tgactgatcc attcttccat
    81661 ctcagacatt tccgtatagc cgatacgcgt cttgacgctg acaggcaaac cgccagcttt
    81721 agccgcttca atcaattgtg ccgctacttc tgggcgaagg atcaagccac tgccttttcc
    81781 acgttctgct acattaggga ctgggcagcc catgttgata tcgattcctt ggaagcccat
    81841 ttctgccata gcaatgctca tttctctaaa aaattctggc ttgtctcccc aaatatgggc
    81901 aaccatcggc tgttcatctt ctgtaaaggt caatcttcct cgtacactgt cttttccatc
    81961 tggatgacag aaactgtctg agtttgtaaa ctcagtaaag aagacatccg gtgctgctgc
    82021 atgctttacg acatggcgaa atacaacatc tgttacatct tccattggtg ctaaaacaaa
    82081 aaaaggcttt ggcagctctt tccaaaaatt agtagtcatt tatttgttac tctccattct
    82141 atcaagcagt gaagtcgcaa tctttctcaa aaacattgtc attatactag gaaacaaaaa
    82201 aagaagcaaa gtgaacagct taaaagatgt ttctgattga gcaaaaaaag actgtgacaa
    82261 aaatcttatc acaattcctt ttccggaata aatggtgttc aaaagcttgc atctgcggta
    82321 ataagtccaa ccaaacgaaa aataggagga gctatttttg tttggctgtt cttattactt
    82381 gatgcagaac agctttttca caacctctcc actaaacggt gttcaatcag ctgaccctcg
    82441 gtattagctc aacaaacgac aaaatatgag gaactatttt cccgtttgtt tctctaatac
    82501 tcaggtcaaa acgctgattt cacaacctct tttctaactt ctcaatcctc ttcctttatt
    82561 gatcaaatac caagtaacgg cgtacaaaac aacgatgaat agcacaagta cgatcatcga
    82621 tgttgctact ggcacatcga ttgttccaag gaatccgtaa cggaaaccgg agatcatata
    82681 aacgatcgga ttgactttcg aaacagcttg ccaaaatggc ggcaacatag agatggcata
    82741 gaaaacgcca cctagataag ttaacggctg caagacaaat gtaggcacga tcgatacatc
    82801 gtcataagac tgagcaaaaa tcccgttgag cagtcctgct aacgaaaaca agattgccgt
    82861 catcaataat gtaatgatga ccatgaacca tgaatacaca tgaagtggta caaagaacaa
    82921 ggaaatgatc gttacgagag agccgacgag aatactgcga cccactccgc caatcacaaa
    82981 gccccaaatg atcacatgcg taggaacagg cgctaccaag atttcttcga tgtttttctg
    83041 gaatttttga gagaagaagg acgaagaaac gttggcatac gaactagtga tagcagacat
    83101 cataatcaaa ccaggcacga tgaattccat atatgaaaaa ccacccatgt caccgatccg
    83161 accaccgatc atttttccga aaataacaaa gtacaaggat gtcgtgatca caggcggaac
    83221 cagtgtttgg acccagatac gcaaatagcg gttcgtttcc ttgatagcta aactttttaa
    83281 tgcagtaaaa taaagattaa acatttttct cctccgtatg attattttct tctgtgattt
    83341 tcaaaaacag ttcttctaaa cgattcgact tattcctcat agaaagaact ttgattcctt
    83401 gtcttgtcag ctgatcgaag attccgttca ccccttgatt tcgttcaact tcgacagcga
    83461 ttgtctgttc atcttcaaat gtacaagcgt atccttcaat cacaggtttg gtctcatatg
    83521 gcgctaaatc aaagataaat gtttcaaatt gcagtttgga tagaagctct ttcatactag
    83581 tattctcgat cagttcacct gattggatga tcccgatgtt gcgacaaagc atttcagctt
    83641 cttctaaata atgcgtcgtc aaaatgatcg ttgtaccatt ttcgttcaat tctcggagaa
    83701 actcccacat ctcgcgtctc aattcaatat cgactcctgc tgttggttca tccaagatca
    83761 gcaaacgtgg ttcatgcatc aatgccctag caatcatcag tcttcgcttc attcccccgg
    83821 aaagcatacg tgcacggaca tttctctttt cccaaagatt ggactgcttc aaatattttt
    83881 cgctgcgttt catcgcttct ttgcgagaga caccgtagta gcctgcttga ttcacgacga
    83941 tttgctggac cgtttcaaag ggattgaaat tgaactcttg cgggactaat ccaatctgtt
    84001 gctttgctcg gactagatcc gtatccagat cataaccgaa gacattcact tttccagatg
    84061 ttttattgac taaagaagta atgattccga tcgttgtaga cttcccagct ccatttggtc
    84121 ctaatagcgc atagaaatct ccttctttca cggaaagatc gattcctcgc aatgcttcga
    84181 ccccacttcc ataaaccttt ttcaaattat ttatttcaag cgcatttgcc atttatttcc
    84241 tatctcctta tagacatgat tctttattgt atcatggaat acagcagatg aaaaaacaac
    84301 ttggttccag cgaaaaatca ggttgctggg ctcaggaaaa tctcctaatg aaagacatca
    84361 atcggacgaa gtcagacaac cttttcagaa aaaacaaatc gaagataaag gattactatt
    84421 catatgtgca acaaaaggag cgtgagacaa aagtaaagaa cacttttgtc tcacgctcta
    84481 aacacgtata aacggcggaa gcaaaagcca agatttttga tccaataaat actttcgatc
    84541 acttcgccta tcccaataca tgccactgcc gcttttcatc aaataacgcg gcttccgttt
    84601 ttgcggtttc tactaaagtc tctgggtaat ccaaaacttt cagcaaggca atcgcatttc
    84661 gggtccttga aggtccttct tttaatttga aatcaaaact gattcctttt ccttctgtta
    84721 cttgttcttc aaagtggaca ttctcacaat aattctttaa aatctctgtc aattcgatat
    84781 catgtgtggc gacaaatgct aaagatggat actccgcaag ccaccgaacg actgaagcgg
    84841 aagaagcaat ccgttcgatc gtatttgtcc cttttaaaat ctcatctacg aagcagtagc
    84901 agcgttcttt ggaagccact tggtccaaca aacgtttgat cgatttgatt tctgaaacaa
    84961 aataactgtc gccttcaaat aaatcatctt cgattgccat ggaagtcaac acatgtccag
    85021 gttgcagggt aaactgttct gcaatcgctg tttggatcgt ctgtgctaga atacagctga
    85081 tggctatact tttgacatac gtagattttc ctgatgcatt ggaacccgtg actaatgtat
    85141 tcttctgcca gttgaccgga ttcactaccg cttcttttaa caatggatga tagatatctt
    85201 tcgctgtcac accgccctca gtaaactctg gtcggcaagt gatgggcata taagtacggt
    85261 aattcaatat tgcagcggct acttctaatt ctcccagcaa ttcccacagc ttgatggctt
    85321 cagttgaatg cttttctaat ttagtgagaa cgaaatgata ggagataaat ggcagcatga
    85381 acatgatgtt gacatattca aaaatcaact ctgcttcact cccactcttc atacgaaatg
    85441 aaaaacctaa tttagggatg tctcttaatg gtttagtttg ctgtttcagc tcttcttgaa
    85501 gtggtgtcgg cagttttgct agctgattgg cggctgaaat cgttgaaacc aaataactca
    85561 tgctattcag ctctgtttct agtgtttgtt tcttcactag ataatagacc gtattgaata
    85621 ctaacccacc gattgccaaa tagattccta gtacttgtcc taaaagaagc aaacccaaac
    85681 ccaccagcgg aagcaagcca agaaaaataa ataaacctac gcgtccaatc tttttacttt
    85741 ttccatccgc tagatattgt tttgcaaaat tatgatcttt ttttcctaaa cgagcgaatt
    85801 gatattggat tttttctctc agttgaggat tttcctgata aaaagcaatc agtttttcta
    85861 actgctgatc ttcaccaaaa tcaaagctgc gtaaacgttg atacaacgct tctgaaccta
    85921 cactagaata ggtactgttg attccttcga atacttcgaa catatccagg tcataccaag
    85981 taagatcatc gatttcgcta tcccatgaac ggaacttctt ctccgtgagc catgcttcct
    86041 tcaagctttc ttctttatca aatctcggtt gataaggaat tttttcccat ttgctacgaa
    86101 ctgtttcctt taatttcaaa cgtgaaaaaa tgtctaaagc aactaataaa ataacagctg
    86161 caataataat taaaacgata aattctcttt gacccatatc cctctccgtt cctttatttg
    86221 ttagctttag tatagcactg ttgcgctatt tgaaaagagg gtaaaaaaac acctttcaaa
    86281 ataaaaggtg tttttttctt gtatattaca tatttatctc tcatttatca aaattgacaa
    86341 ataatcatag ggaggaattg ttgttaattc ttgtttattc tccagtgcat tgacaactgt
    86401 cccaagggaa aggatagcct caggtactat tttttcttgt tctgttggat tagctaagcg
    86461 aagaacaaat ccttgttcat gaaaataaga aggataaatc gatgatacaa ttaagtcttc
    86521 aggtaattca atcaatgaaa atttacgagg aacatcaagt tcattttgta atggccaaat
    86581 cttgttatct aacctgtgaa taaatacatt cagtttctgc ttttgataag aaatagattg
    86641 ttctaaccgt ttttctgcct gttttgccac tttgaactca ttaaatcttc cttcttctac
    86701 attaaatcca aaagtgactt tatactcacc tatctcttga gctagcggtg tttccatcat
    86761 gacatgccct tcatttgtcg tatctcctga agctcgccca ggtcgccaag caagattagg
    86821 ttttccaagt tcccctgttg ttgaaaataa ggttatgatt aattgatttt ctatacgttc
    86881 atactctttt aaaccatctg cataaaacgt aaaataatga tcattttctg ccacagagac
    86941 actcttatcg aatatttcta aattaacagg tttctctacc atagtttctg accaattcgg
    87001 aggaatgaca tcaggggtat tttcaataaa tccgttttga atttgtgcaa ttgatttttc
    87061 agatttatct aaaacattaa ttgctaagcg catacgatgc gagtaaacag tattatgaat
    87121 tttgagtgtg ccttcaacga tttgactttc tcccagactg aacgatattt cataagatat
    87181 ttcttccatt tcgggttttt cagataaacg atcttttaaa tctttaggaa gttgagcttt
    87241 tccgtaaaca actaatgttt cttgtaaaga atctttatat actttagctg tttctaattt
    87301 tagagatagt tctgtatctc cttctaatgg tgaataatca tacgtatcgc catcatttgc
    87361 tgaatcgatc aaatgaacga aatcaagata ttgtctatct ccaactatca aattcaattg
    87421 cccatcttta aaagaaagtt tatatttatt gttacttatc tcagttttgt ctatctcgat
    87481 tgctgtttct aatttttcat tatttttctc aaattcaaca acagtgtatc ctagtgctgg
    87541 cacatttaca tttattttta tgtcaagttc ataataagct ggttcatcaa aatattcgaa
    87601 acctgtagca atcatccgat aagcattttt ccgttctgga aaataaactt ctttttcaat
    87661 gatattatag ggactacctt tgaagtgtat tttctttgaa tcagctacta catgcacgat
    87721 tttcgatcca ctataattct cagtcgttgt gttgaaaaca aggacttcat tcgattttag
    87781 ctttaatgca tcagccatcc gttttacaat aaggttttcg attccgtcag ctatctcatt
    87841 agcttctttg attcgatgga aaatatcttc cgcaacatta tctgaaacac agccaccaat
    87901 actatcatga gcctggtttt gcaaaatctt tttccataac cgacgaagta ggcctttact
    87961 gatatggata ccatttcttt ctgcaatcag catgagcggc tcaactcgtt ttagaatttt
    88021 ttgttccaat ttaaaatttt ctattttcat ttttgttctt actgagccaa tagaacgatg
    88081 aacacgagag taaaccggct gacgaagttc acctttatat tcaggtaatt cttttttgtt
    88141 tctgataact tctacataag aaggataatc tgaaataata ttgtggaatt tactgtattt
    88201 attcaacttc tctacgactt gatcaaaatt taaaatcatt gacttttgat ctacacccga
    88261 aggtactaaa atatctttgt tttttccttg catatgaagc atttcaactg cttcatccaa
    88321 cttttctttt gcaaattcag gaatatcttt aattgcgtct aaggtcatca ttccagtcat
    88381 ataaccaaat ggaaaattca tggcataaac aaatttatct cccaatcctt tccagataaa
    88441 ataaggagat ggaaccatcg tttcaaagtt taatcctcgc caacacatga aattatcgat
    88501 ttctacttga tgcaaaagtg taggcaaatt cgcattgaac ccaaacgtgt caggcaaata
    88561 ccctaccatc attggatctc catatttaag gatcgtatca ctgattccaa tcattaagtt
    88621 tcttaaaatt gattcagcat ccactaataa ggcatctgtt tgtgcatacc acggtcccac
    88681 gaatagttgt cctgttttca tcagtcgttg gataacctta agcttttgcg gattgatctc
    88741 caaatactca tcgacgattg aagtttgtcc atctaaacaa aagtttactt tagggttcct
    88801 ttccaattca tctagaactt cagtaaagac ctgatcagac aatacgatgg catcttcatt
    88861 tgtaaaatac cattctctgt cccagtgcgt gtgttgaatt atatgtgcat ttaccatatc
    88921 agattctcct actttccttc ttctactgaa tttacttgtt gttctttttt atacttgatg
    88981 gattttagtg cattgaccat taacgctgta accactcccc caataacaat tgatactaaa
    89041 tataaaggta tattcgtaac aaaaggaatt gccataaagg ttgaaagcat tgtttcttga
    89101 gtaacaccaa aaaatccatt tagaccacat gctactgcag tgcccaccac gatgcttggt
    89161 attactcgta aaggatcttt cacggcaaac gggatcgtcc cttcagtaat ccccacaagg
    89221 cccataatca tagctgtctt tgcattatct cgttccgatt catcataaag ttttttgttt
    89281 aaaattgttg ctaaaaacat tccaaatggc ggaatagcaa ttcctaataa catggctgta
    89341 ctaggtccaa agcttccgct tgaaaaagaa gcaaccccaa aagcatatgc gattttattg
    89401 ataggtcctc ccatatcaaa cgccatcatt cctcctaaaa tagccgacat caaagcagca
    89461 tttgctcctg acatgccttc tagccaatta gtcagtcctg ttgtcattgc ttgaataggc
    89521 gtagctagta cataccataa tatgattcca acaactaatg tagtaacaaa aggaatcagc
    89581 ataattgatt ttagactaat aacttgcatc ggtactttta cttttttcaa tgcattagct
    89641 aaatagccac aagctaatcc agcaaccatt cctccaataa atcccatacc aagattttga
    89701 cacatcatcc cagtgataaa agctggtgct agaccgggac ggtcagcaat tgaatatgcg
    89761 atataggctg aaatcatcgg tacgataaac tgtaatcccg tctgaccaat cattcgcagg
    89821 actccccaga atgtatccgt ctggtcccaa acacctgtgc caccaaaaat gactgcaata
    89881 gaagttagta accctgctgc tacgacaagc gggatcatat aggaaacccc actttggaaa
    89941 tgatttagaa tttctcttcc ttgtttcttg aattccatta gtaactcccc cacgatatat
    90001 tttttatttg ttaattaatg caattgcttc atcaatcgtc tcttcaccat cttttactac
    90061 ctctgaggtc cctactgtta aaatcggttt accgtcaaag cgacctcgtt ctgaaacatt
    90121 tgtatctact gcaaatatga caacatctgc ctcggaaaca tccgaaattg aaagtttgtt
    90181 ttctatcccc atagccccct gtgtttctac tttaatatct aaccctttct tcttcgcaaa
    90241 cttttctaaa ttagcttttg ccatataagt atgggcaatc cctgcgatac atgctgttac
    90301 tgctactatt tttgtcatat gaaattcctc cttttaaaat gatagagctt ttaccaattc
    90361 ttttttattt ctcgaatctt ttattctttt aacaaactcg tcatccatca atcttccaga
    90421 taattctgct aaaatacgta aatgattagt acctttatca gtgtctttta ttgctaacaa
    90481 aaagacgaga tcaactggtt gatcatctaa tgcgccccat tcaacagacc gctttaactt
    90541 ggctacagcc actgttgatt caattactgc taggcttttg ccatgaggaa tggcgatatt
    90601 tttcccaatt cctgtggtca tatggttttc tctgtcaaat acgtcttttt gaaattgttt
    90661 gtggtcagac acaaacccat tagtctctaa caatttcgat aatttttcga ctacactttt
    90721 tttatcagat gcatttaaat ctatcactat attatttata ttgatttttt cactgatcat
    90781 ttataagcct tctttcaata tataaactaa tttttcaaac gacgaactcg tttttaaatt
    90841 tgctaataac tcatgattcg aagcgatttc attgaatgtt tcataaattt tattcaattc
    90901 aggttttact ttttcattaa gtgcaaaaaa gaaaacagaa tgaacaagtg tcccatccca
    90961 atcaattcct tctggattaa cgtagacaca gattactggc ttttttataa aatctacttc
    91021 gatatgcggc atagcaaaat cattcatcgc tgttgaagat agtttttctc ttttgattgc
    91081 tccctctagt atcccttctt tcgcgtaatt ttcttttacc aattttttgg taattatatt
    91141 taaaacgttc acttgattat cctttatttg gtgggtaaaa aagcaaaatc gtttatctaa
    91201 taaatttaga aaagcatctt ctgtttgttc atttaactgt agatactgtt ttacttttct
    91261 gacatctgcc cctaacatca aaggactaac aacaataaca ggaaaatttg tattttcaat
    91321 cggaatcgtg cttataacaa gttcatcagt gacttttcta tcttgtagtt cattgatgct
    91381 tagtacatct tctatctcaa ccatatctgc aaaaccgtta tttattcttt gctctaataa
    91441 ttttgatgtt ccatatccgc tactacaaac taatatcact ttcgttttgt caggtttgta
    91501 acgatccaaa agtgattgaa tatggagtgt tacgtaagcg atttcatctt cattaaaatg
    91561 tatacagaat ctctcttcga tttcctctaa taaatctaca cttatcataa atgacctttt
    91621 aaaagaatat ttgattttgt ccgtataagg gttatagata tttactccca atttgagtct
    91681 tttaactgct gcattgagat gtaatactag attattgatc aattcttcat caggataaaa
    91741 ttcatttaat ttaattctta ctaactcttg tagctcaaca cccatatcta aataggaaag
    91801 cttcgtttga tctaagtcgt gattcatagc atttttttca atcgaagtaa tgtgaatgtc
    91861 aacataagct tgttcatcta ttggcacaat aattgaaaat gctttttcaa tcattttgat
    91921 taaaataagt gtattctttg agatttcttc ttcagaatta ttactacgtg ataagaaatt
    91981 gcttgtttca atcctttcta tcgcaatagc aaggtggata gctaaagttt gaaattcata
    92041 atctgtaaat ttcaattgtg tcttattcat gtatcgatta agcaattcgg ctactttttt
    92101 caatatgtcc ttatttaaga aattattcgc ttcaccaatg aaattgatat tcaagtctaa
    92161 gagatctgtt ttactgttag atgctgtaaa gccaccccaa taatagttca caacttctga
    92221 catcaacctt cttttacttt tttcatcagc tttgatgcgc acgccatttc gatctgaaac
    92281 taaggacatc ccatgcttgt ttagtctttt tctaacatct ttcattgtgc tttctaccgt
    92341 cgacctgctc acgtataatt cgtcagcaag attttgaatc tttagagaat cattagtatt
    92401 caataattta gcaaacacat aagttagacg gtcctccgga gagtctgcga tattgatttt
    92461 atgactggat aataaatttc gaagtgtttc tttttttcca ataagcgaaa cgcctttttt
    92521 aggttgaacc aacatttgta catctggcat tttttggatt atttctttca aaattaaaat
    92581 atctttgcta attgttttcg tagatacata taattgttct gataattctt tgtaagttgt
    92641 gtgctcattt tcaatcaaaa agtatagtat tttcatttgc cgttcgctaa attcgatgcc
    92701 cattatcttc acctcctgaa tacagcttaa gtgtacaatt attatctcta ttttcataca
    92761 gaagaaagtt cttgattaat gtagaagttt ctaatattct tgattatttc aaatcaataa
    92821 aaaagcctgc aatatttata tcacaggctt ttttctctat taaatatata taagataata
    92881 catttttcta ctagttctca ctaatcttgt ataattaaac cctccgcaac ttgacggaga
    92941 tggagaagat gcccccgtct aatctagcgg tcatctctcc tcccattcct tccaccaatt
    93001 tttttgacag gtaaagcccg attccgctag attccgtatt tgtgcggctg gtattttcgg
    93061 tataaaaacg ctggaagact ttttcaacag aggtttgcgt tcctggtttg ataggattgg
    93121 ccactgttaa tcgaatgaat ggatcctctt ttgaaaatgt cacctttgct tgtccatctg
    93181 cataacgcaa taaattctgt atgatatttt gcagcactcg cagcaacatg agcggatctg
    93241 ctaatacagt tgtatttatc gagtgttcag cgaacgctac ctcgatattt ttctcagaaa
    93301 attgttcata aaaagagaaa aatacttctt ccacctcttt agaaaaagaa agcgtatgga
    93361 gatccatttc tttttgcttc gtctctattc gagcaagatc ataaaactga tccgtcatac
    93421 tgagtaatct tgcaacagat tgtttgatga tcgttaaata cttctcccgt ttctccgtat
    93481 cctctacctg ttccagtaat tgtacataac cgttaatagc agtcaaagga gttctgagat
    93541 catgagaaag gccgacgatc gatagtctga tgttttcttc catttcttga aatgcttgtc
    93601 ctttttgttc attttcatcc aaccatgtat tcagtgcatc tactaggtcc attagattct
    93661 tttctcgaaa ttcgactgaa agacgaccac catattcttg tcgttcagaa agagtggcga
    93721 ttttcttagt taatctcttg atttcccttt gcaggaagaa aataaaactt cccataaaga
    93781 taacaacgag aagcaacagc catttaatca aatctaaacc ccactcccca caccgtatga
    93841 atatacacag catgtgcctt tgctagcttc cctcgaagat tggaaatatg catattcact
    93901 gttttctcac tatcaaaata tggttcttgc caaactgttt cataaagatt tgctcgcgaa
    93961 aatacttttt tcggatgttc taaaaaaagc ttcagcagat cgaattctct tcctgtcaaa
    94021 tggacagcca caccattcac atttacatcc ctcgactctt tgtccagtaa gatttccttg
    94081 taatagatgc gttgcgacag atcttttact tggacagaag tctgatgacg aagttggatg
    94141 ccgattcgta acaaaagttc ttcgatatca aatggtttcg tcacatagtc atccgctcct
    94201 gctgccaaca aggaaacttt atctctttga tcgctttttg ctgaaagaac gatgatcgga
    94261 acattcgatg tctgtcggat ttctgctaac aatgcttcac ctgaaagccc tggaagcatg
    94321 agatctagaa ggatcaaatc gacaggatat gtgcttaaca ataattttcc ttccgtacct
    94381 gaataagcat caagaagttt gtatctctgt tcaagaacct cctccagtaa ggaatgaaca
    94441 gcttcatcgt cttcgataat caaaatagtt tccagcagga ccacctactt aatgtcagat
    94501 ttttggaaaa taaacattcc tagagctgat gataccacga ttgttactag actgaccaga
    94561 atcattttcg gtgcttgcga ataagttgct tgttgcgcaa agtccgtata catgagccac
    94621 gtttccgtaa accactccgt tagaaattcc aagcctttga tttttgcgaa aacaccggga
    94681 atgaaggccg ttcccatgat ataaagaaaa gaaagaagca aactgacact ggtacttcta
    94741 gtgatgaatg tcaaagccac tggaacagat aatgtcccta atgtcagcag aagcaataca
    94801 ggaaatactt ttagaacata atttccatag tttttgattc cctcaacttc accaaatccg
    94861 aaagcaagtg tgtaagcaag catggctagt cccgtgatca aaaccacgcc aagtgttgtg
    94921 atcaaaagcg taacgagaag tttcgacaca taataagtca ttcgattccg tcctaaagat
    94981 aacgtattgc gaatcgtacc gttttgaaat tcttccccaa tataaaagca cgcaaatgct
    95041 gcgaaagcca gaagaatcca tgcagccatt ttttctacca ttaaaatccc tgttgcaccg
    95101 ttgatgactg tatccgttgc ttggtttaat tcattgccgt attttgtatg catataccat
    95161 tcgttccaag aataaaaaag cggaagtacg accatcagtc ctagtgagac ccacatttta
    95221 cggctcttcc atacttttat tttttcagca gttaatagat taaacatgtg gattgcctcc
    95281 agttaattgt aagaaataat cttccagttt ttgcccaact aggtgaatac catccacagg
    95341 aacttttgct tctaccaatg cttgattgat ggctgctact tggtcaattc cttcaaaaag
    95401 ctggataaca cggctagatt gtacaaaata atccctataa ccaagagagt cgagaaccgt
    95461 tactgcttgt tccgtcgccg aagtgtcaat ttttataaat tgacgagatt cttgtgccaa
    95521 ttcttctttc gataattctt tgatcaagtg tccttcatgc aaaataccat agtgagtggc
    95581 gatctgtgac aattcatcta gcaagtggct agaaagcaag acggtgatgc cccgttcttt
    95641 taccaaacgt tggatgattt ctcgcatttc tgccatccct gctggatcca tcccattcgt
    95701 cggttcatcc aaaatcaaaa attctggatt cgtgatcagt gcatttgcaa tagctaaacg
    95761 ctggcgcata cctaaagaga aattctttgc tttctttttc cctgtatttt ccaatcgcat
    95821 cattttcagc aggtcttcga tttctctatc cgacacaccg ccgttcgctg cttggatacg
    95881 taggttatct cttgcagtta attctggata aagagcaggg gtttcaatcg attgacccat
    95941 acgtcgtctt gctgcctgca aatccgtcgt tccaaataat tcgatcgaac cttcatcaat
    96001 cgagatcaaa cccataatag ttctcataaa ggtagactta cccgctccat tttccccaat
    96061 caatccatag atcattccac gtttgatttc gattgatact ttatctaatg ctttggcagc
    96121 accgtatttt ttggttatac cagttgcttt caagaccgtt tcatttccaa aatccatact
    96181 tatccttctt tcttattgat gagtgaagta tagttgacgg gtataaagaa agcagccaga
    96241 aatgtataaa gaaagtgtaa attttccaat tgaatgtcaa aaaaaacaat cggacaatac
    96301 gtgtctttcc tattatcagg cagtttgtta tacgcttgta tcagtttcct gattctttct
    96361 tttcgaccaa agtcgtttct ctgtattcct cttcactgaa aatttttgct tctttcagat
    96421 caagcttgag taattttacc agaccggtta taaggataac tatagcaaga ctccctccca
    96481 gaaaaattag actgtctcgc agacgtggtt gcgttgtctt ccaatcaaag agcgcaccaa
    96541 acagtgctaa tccaagtgga ctggccacca tggtaatcgt tgttatcgtt gacataagtc
    96601 gtccttgtat atgcgttgga acttctcgct gaagccagac catataaaaa gcaaaagaaa
    96661 acattaatcc ttaaaaacgg acttatgaaa aataatacat gccgtttggg atttacaatt
    96721 agctaccaaa taagaggtta tgacaaaaga cttttcacaa tcccttcttc cgaataaacg
    96781 gtgttctcct gccaactcct cggtcacaag tcacaatatt tatcaaacat gagaagcaat
    96841 ttttgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tcagaagcgg
    96901 ataaataata ttgtttgatg atactttatc tttttcccgt ttgtttatag atcgaatgat
    96961 attatagacc aagaatccta cctattaaca tagctaaaaa cacaaaaaag gcactttcca
    97021 aattgtggaa agtgccagaa aagttaggat taaggtaact gcgctcagca ttgcttcgcc
    97081 cagtacgatt ctcgtaactc gtgaactcga acgataatcg caattaacgt tttgagaact
    97141 gtgaagcttt acgggctttc ttaagacctg gttttttctt cgtatcattg aataagtttg
    97201 aaaaaccttg atttataaag gttttcccgt aaatatattt tattatattt gattaaattt
    97261 gaaatgtttg tgttctaaaa tgtgttctaa tttaaaggca gtatatttcg tattttagat
    97321 taaattttta ggctcattca ttctcaaatc cattctattc agtcaataaa aattttaaaa
    97381 agactttata aacaaagatg ttcaagcgag catcttattt ttttgtgctt aatttgaaag
    97441 gagaacattt catgtataaa aaacaaaaaa agaaattatg tgtattaact attttgagtt
    97501 tggctgttca agcaattgtt ggagcaattg ctcctacgat tacttttgct gatgaaatta
    97561 cccatccaca aacggtaacc gtagaactag atttagcaca tcaatatgct gttgaaggaa
    97621 cttttagtga tggtcgtcca atgtcagaag tcactgttcc gcattatgca gtgtacaacg
    97681 gctttaaaca agatattttc tgtattgaac caggagtccc gatttacaat gagttcactc
    97741 ctggctatga gaaaaacccg ttaccagata tgtccgataa agccaaatta gtttccgttt
    97801 tatggaaaaa agtaggtaca gatgcagata ctcatattgt ggcacagaag atgatctggc
    97861 aagaagttaa tgggtatacc cttcactcaa taaaacgatc agatggtagt gccgtaaata
    97921 tcgcagccat tgaggcaaaa ataaatcaag ccattgacga ttatcagaag aaaccaacct
    97981 tccataatag tacggctaaa acagtattag ggcaatcgac tactgtgacg gatacgaata
    98041 atctgaattt gtcagagttc gatgaggttg tggaaaatgc cgcaaacatt gattatcgtg
    98101 tgaatggtaa tcagttgata atcaccccaa atgccaattc aaaagaaagt ggtgtgctga
    98161 cgcttaagaa atctgctggt accggaacac ctgtcgccta taaaaaggct ggccaacaga
    98221 ctttaatggc cggggcgatt gataaaccta atacctacac aatcaaaatt gatgtggaaa
    98281 cggagggttc tttaaagatc aaaaaagtcg ataaagaatc gggtgatgtt gtaccaggaa
    98341 cggttttcca tttagacttt ggaaaaactt tacctgcaaa agacgtgact actgacaaag
    98401 aaggcattgc tacattggat gagattcctc atggtacaaa agtaaccatt accgaaaaat
    98461 cagtaccggc gccttatacg attgatacca cccccatgac taccaccatt aaagcaggcg
    98521 aaaccattta cgtgacttca aaaaacgcac gggaaaaagg gcaaatcatt ctggataaaa
    98581 gcggagttga aacagggagt gatctttgga atgacaatta ttccttagct ggtaatacgt
    98641 ttgccattcg caaagacagt ccaaccggtg aaatcgttca agaaatgacc acggatgaaa
    98701 acggtcatgc ggaaacacca aaagagattg ctaatgcgtt ggaattggga acctattatg
    98761 tgaccgaaac taaagctagt catgggttcg tgaatacgtt caaacctgta aaagtcgaat
    98821 tgaagtatgc caatcaaacc gtagcccctg ttaccagtaa cgtaaaaggg caaaatcaag
    98881 aagtcactgg cgaaaccact ttgacgaaag aagacaaaga tactggggat aaagcacaag
    98941 gtaaggcagt ctttgagggt gctgaataca ccttgtttac tgctaaggat ggaaaagctg
    99001 ttaaatggag tgaggctttt aaaccagagt tagcgaaggg aacgaaaggt tctgatgaaa
    99061 cggtcacttt gactttagac gaaaagaacc aagttgccgt taaacattta gctatcaacg
    99121 agtattattg gcaagaaaca aaagcgcccg aaggatatag ccttgatgaa acaaagtatc
    99181 ctgtatccat caaaaaggtg gatgatagcg aaaaaaatgc cgtgattacc cgaaatgtta
    99241 cggcaaaaga acaagtgatt cgctttggct ttgatttctt taaatttgct ggatcagctg
    99301 cgggcactac cgaaactggc ttcaatgatc tgacctttaa agtgtcgcca ttggaaggga
    99361 ccaatgaaat cacaggtgcc gaagatgaag cgaccacagc ttataacgag caattagggt
    99421 ttgatggtta tggcaagttt gaaaatcttc cttatgggga ttatttactt gaagaagtag
    99481 aagccccaga aggttttcaa aagattacgc cattagaaat ccgttctact tttaaggaaa
    99541 acaaagaaga ctttgtgaag agtgagtatg tctttaccat taccgaacaa gaccaaaaac
    99601 aaccaattaa aacggtgacc gttccttacg agaagctgac gaacaaagca ttttctgtta
    99661 gtttgaaccg tttaatgctc tatgatttgc ctgaggaaga agatagttta acttctcttg
    99721 cgacttggaa agacggaaac aaagaattaa cttctctgga ttctaccgag ctagttgata
    99781 aattgagtta caatctacat gaaatcaaag aagactggta tgtggtagcg caagccattg
    99841 atgtggatgc gacaaaagct gcccaagaaa aagatgaaaa agccaaacca gtggtgattg
    99901 cagaaacaag cgcaacgttg gcgaacaaag agaaaacagg aacttggaaa attcagcata
    99961 aattaaccgc cgaacaagtt ttaaataaaa ctattgtctt attcaactat gtgtatgaaa
   100021 ataaggaagc ttttgaagca ggcgataagc cagtagcgaa ggatgttagc ttgaataacc
   100081 aagcccaaac tgtcagttgt acagtggaac accatgtttc tatccaaaca aaggcccacc
   100141 tagaaaacgg ttctcagacc tttactcatg gtgatgtggt ggatatgttt gatgatgtgt
   100201 cgattactca tgatgtactg gatggctcaa aagaagcttt cgaaacaatt ctgtatgctt
   100261 tattaccgga tggtacaaac aaagaaattt ggaaatctgg caagattgat tatgaagtaa
   100321 atgataaaga attcaccaaa actgtgcttg cgaaaaaagt agataccgga aaatatccag
   100381 aaggaaccaa gtttactttt gcggaaatca attacgataa agatgggaat atcaatggaa
   100441 aacacaatga agatttgaaa gaaaaatctc aaaccttaac accaaaagaa gttccaacca
   100501 tactaagtac gccgaaacaa ccggaaacac caactgttcc aagtggctct caagaatcta
   100561 gtcccacagt gaagaccttc cctcaaaccg gggagaaaaa ttccaatgtt ttactgttca
   100621 ttggttttac tttgattttt gcgacggcgg gctattattt ctggaatcgc cggaactaag
   100681 gtgatgagat gatacaagta aatcctaaga accaacgtgc gcgaccgcct cctaaaaaag
   100741 tagtcgcgct atttttgtat ccaaaactaa caatgaaaag aggaaaagaa gatggaattg
   100801 aaatttgtcg tgccagatat ggctgaaacc tttggaaagt taagttatgc cggtgaagga
   100861 gaaattataa cagaaggata tggacggaat actacggtga ttggtcgcag ttatcatttg
   100921 tattccagta agcaacgggc cgatgatatt gaggtggtag tagctgcgga agccggtgaa
   100981 aaggattttg atcaagacca accgctaaaa gccgtgaatc cccatttggt tgccaaaggc
   101041 tatgagattg agaatcgtgg gtttactgat tacgtgttgt atgttgatga tttagtgaaa
   101101 gcataggagg aaaagaagat gagattaaca gaaggtattg tcgtagattc aggtttaaca
   101161 tttgggaagt tgcgtttttc cgcattacgc cgagaagtac ggaagcaaaa tgaggatgga
   101221 acaattggta atgaggtaaa agaacgaacc tataatttaa aatcctctgc acaagggcga
   101281 atgattcaag ttagtatccc agctaatgta cccttacgcg agtttgctta tgatgcagag
   101341 gtagagttgg tcaatccaat cgtggatacc gttgccaatt atgtttttcg agaaggaact
   101401 accgttaatt ggttcattaa ggcggatgat ttagtcttga agcggcagcc gaatcaagga
   101461 aatcctacga accaaaatga aagaaagaaa taggtgaaga ttatggaaat taatgttgaa
   101521 catattttag attgtctcga tcaatatgga aaaggcgagc tgactgagga acaactcgtt
   101581 aaagcattaa cctctgatga aaaaatgttt ctgattatac atcaaggttt acttggagaa
   101641 aatagcgaca gtgaagaaga ctctgatgta ctagactggt taggagaaga agagtctttc
   101701 tttatagttg tcgaagtaaa tgaaaactta tgtcggcagg cagaatccat tttggaagaa
   101761 attggtgtgg agatgccgga tgctattgaa ggctttttaa atcaattggt tgaaacgaaa
   101821 caactcccct cctcgtagca gtaaatgact agcataactt tttgaaattg cctaatgaaa
   101881 tcctattggg ctttttcgat tggaggtgga aaccatcaaa atgtacaaag gacatcgcat
   101941 acgcgcagga gatcagcact tggtttatca ctttgttctt ggctggctac tcgctctgtt
   102001 catcggttgg atgagcgtct tttattttca agagtttaga caatttgata tttctaagct
   102061 atcactttct actattgaaa tcgtttggtc tataaaagat ttagtatgtc tgcttggaag
   102121 tctcgctttt tcaggagcta tgatattgct ttatattcac ttttttcttg atcattggcg
   102181 aagcttgtgg catcgacaaa agctagctcg gatgattcta gagaaccatt ggtatgaagt
   102241 gaaacaaact caaagtgaag gctttttcaa agatttgaat agtagccgaa ccagagagac
   102301 tatcagttac ttccccaaaa tctgttatcg aatgaaagat ggattactgt ctattcgcgt
   102361 tcaaatttca cttgggaaat accaagatca gcttttaaaa ttggaaaaga agttagaaag
   102421 cggactgtat tgtgagttag tagaaaagga actcaaagac tcctatgtgg agtatacttt
   102481 actgtatgat atgatcgcca atcgaattgg gatagacgaa gtagtggcag aaaatgggac
   102541 tctgcgattg atgaaaaatc aagtatgggc ttatgattct ttaccccata tgttaatcgc
   102601 tggtggcacg ggtggaggga agacctattt cctcctcacc attatcgaag cactattgaa
   102661 gtcagatgca gaattgttta tcctcgatcc caaaaatgca gatttagctg atttaggtac
   102721 ggtgatgcct catgtttatt cacaaaagga agaaatttct gcttgtgtgg aagatttcta
   102781 tgaacgtatg atggctcgta gcaaggcaat gaaagaaatg tctaactaca aaacaggaga
   102841 gaattatgcc tatcttggac ttccacccaa ctttttaatc tttgatgaat acgtggctta
   102901 tatggagatg ttaacgacga aagaaagtgc ggtgattttg aataagctca aacaaatcgt
   102961 gatgttgggt cgtcaatctg gtttctttct gattttggct tgccaaaggc cggatgcgaa
   103021 atatttagga gacggaatcc gcgatcaatt caactttcgc gtggctttgg gtcgtatgag
   103081 tgaactcgga tattccatga tgtttgggga ggtcgaaaaa aacttcttta tgaagcacat
   103141 caaaggtcga ggttatgtgg atacaggtgg cagtgtgatt agtgagtttt atacgccact
   103201 tgtaccaaaa gggtatgatt tcttagattc aattagtaaa ttagaaaaga tgaatgattg
   103261 agtgatcttc aatactgact ttatacttca agtaacgtat aatactttta tatagtagga
   103321 agaaagggga taattaatat ggaaagtaat gattcttatt tagagtatgc aaaagcaaat
   103381 aaggataagt ttatttctta tattatcaaa gggaaatccc ccgaagttgg acgagacgca
   103441 gtttttatgg cagggagtcc tggggctgga aaatcagagg ttgccattgg attagctgag
   103501 aattatgata accatgtgat tattgatgcg gattactttc gcacccagtt tcctgattat
   103561 aatggaaaaa actctagtct ctttcaaaaa gcatcttctt ggttggtaga gcaggcattt
   103621 agatatgtct tagatcatgg ctattctttt attctggatg caacttttgc aatattaagt
   103681 gctgaaaaaa atatctcgcg ggcgttgaaa aaacattttc gagtgacgat tttctatgtt
   103741 tatcaagacc ctaaaatcgc ttggaaattt acacaagaac gtgaaattgc agagggacgt
   103801 catgtgccga aaaaggcatt tattaacgct tttttcaaat caagagagaa cattgcaaaa
   103861 gtaaagagta aacatccaga tgtattgctt catatcataa taaaagatta tacgaataat
   103921 atttccgaag ttcattatgc tacggataat ctagaattat ttttaccact agggtatagt
   103981 aggaaagatt tggaggttca attacatgac tgagaaagaa caagtaacga aaattgtaaa
   104041 gaaatacaat aagagcattg cggatttatc ggaaaatgct actgcaaaag agttcaaaac
   104101 ggtgattaaa tatgtagccg atcaggccaa tgaaaaacaa cggaaattag ttggattaaa
   104161 taaaaaatag taggacaaat taataatgta tgagccaaga gcaaaatgtt cttggctttt
   104221 ttctttgcaa tgaatgaggt aatgtatgag atttttagat ttattcgccg gtattggtgg
   104281 ctttcgttta ggtatggaac aggcgagcca tcattgtatc ggtttttgtg aaattgataa
   104341 atttgctaga cgtagttata aagcaattca tgatacaagt aaggaggtgg aaatgcatga
   104401 catcacaagt gtatcagatg agtttattca atccctcgga ccagtggaca tcctttgcgg
   104461 cggatttccg tgccaagctt tttcaattgc gggaaagcgg caaagatttt ccgatactcg
   104521 aggtacttta ttctttgaaa tcgctcggtt caccactctt ctccgaccta agcttttatt
   104581 ccttgagaac gtccgaggat tgctcaatca cgaaggaggg gctacgttcg agacgatcct
   104641 ccgaacgctg gatggattgg ggtatgacgt ggagtggtag gtgcttaact caaaggccta
   104701 cattccccaa agccgggagc ggatattcct tatcggacat tctcgagacg catgtaccga
   104761 acaagtattt cctatcattg gaccgtcttc aacatctgat caaaacatca gaaatttggt
   104821 aaatatcaat ccttccaatc gaggaatggg tggacaagtc tatggttcag atggcgtagc
   104881 gccaacctta acaggtgatg aaggaatcaa aatcgcactg ccagcaaggg atggaatctc
   104941 tgtagcagga ctattaccgg gaaagtttga acaaggtaat cgagtttatg aagttactgg
   105001 aaccgccccc accttgtcaa cgaaacaagg tggtacaaaa atcatgattc gaaaaaatga
   105061 aacagaatat caagaggtga agccagaaga cagtgtgaat ctggcttttc ctaattccac
   105121 aagtcgccga ggtcgtctgg gaaaacagag tgttcatacc ttactaacag gagaccaaca
   105181 agcgatcgtc acggatcagt atcaaattcg gaagctaaca cctagagagt gttggcgact
   105241 tcagggcttt cccgattggg cttttgatcg agattctcaa gtcaattcag atagtcagtt
   105301 gtataagcaa gccggaaact ctgtaacagt tccggtcatt tttgatattg ccagaagatt
   105361 aaaagagttg gatgtacatg gtttatgatg agttgattgg agaaatttat tgggtgattg
   105421 gaaagattca gtcagaccca gaattagaag aacaattgcg acggttaaaa tttgatattc
   105481 gcaagaatgg tgtcaaagtc gctggcgatc catatttaat gaatgaggag acggatgctc
   105541 gaattgaaat aaatcaagta attgcagaat ttgagcggat tgcggaccaa gcaaaagaac
   105601 cagatattcg tcaatacttg ttagaaatga aagcagagtt ggaagtaaat ggtattacag
   105661 atgagtaacc taaaccaaca caactgactg ttaggcgctg accgcggagg attcgcgaag
   105721 cagaaatcct ccgtggtgct gtgcctgttc atggacggcg ttagccgacc atgatgtctc
   105781 acccccgtat ctaacagggg ggtacaaaaa cacaaaaaat aagtaagcaa ccattaagaa
   105841 tgcttgttgt atcaaagata gtaagtaatt tgtataggtg ttaactcatt tgaaaaagtt
   105901 aacaccttga atttggaggt gagaacttgg cacaacggaa tttagattat cggctattaa
   105961 aagaccgacg caacgaatac ggcgtttcac aaaataaatt ggctacggct tgtggactta
   106021 gtcggccgta cttaaatcag atagaaaatg gtggcgtaac cgcatctata aaaaccatga
   106081 ggaaaatttt tgaccaactg gaaagcttta atcccgattt gcctttgacg ttactgtttg
   106141 actatgtaag gattcgcttt cccacaacgg atgcacgaaa aattattcaa gaaattctcc
   106201 atttgaaatt tgagtatatg ctccatgaag attatgcctt ttactcctat caagaacagt
   106261 atgtcatggg tgatattgtg gtgatgttgt ctcatgaaga agataaaggt gtgcttttag
   106321 aattaaaggg gcgaggttgc cgacaatttg aaactttttt actcgctcaa aagcgtagct
   106381 ggtacgactt tttcgaggat tgtctaaagg ccggtggcgt gatgaaacgc ttggacttgg
   106441 caatcaatga tcgagtgggg ctattggata tacctgagct aacgaaaaaa tgtcagaagg
   106501 aagaatgtat ctccttgttt cgtaccttta aaagttatcg ttccggggaa cttttaaagg
   106561 ctgatgaaaa ggacggcatg ggcaatacct tatatatcgg cagtctcaag agtgaggttt
   106621 atttctgttt gtatgaaaaa gactatgaac aatatatcaa gttagggatt ccattagacc
   106681 aaactgagac gaaaaatcgt tttgagattc gactgaaaaa tgaccgtgct tttcatgcga
   106741 ttcaagattt gttaaaaggt cgtagcattg agagcaccac gttttccatt atcaatcgtt
   106801 acttgcgatt tgcggataaa gtagaaggta aaaggcgaac caactggccc ttgaatgaac
   106861 aatgggggcg ttttattgga cggaatcgga aagagattca attaacttcc gagccaaaac
   106921 cgtataccat tgaacgaacc ttgaattggc taggccgaca agtcgcccct acgtggaaaa
   106981 tggctaagga gttggatcga ttgaatcgga caacctatat ccaggatatg gtacagaatg
   107041 cacgcttatc agaccgacat aaaaagattt tggagcaaca aagtatggca attgaaaatt
   107101 tgattatatg aaaagaggaa tcgtcatggg aattgtaaaa gatatttttt tggtatttgg
   107161 tggcagtatg cttggtgtta ctgtgatgtg cttgatgaat gcaagtgcag cagcggatcg
   107221 agcaatggaa aagaaaggaa agtgacaaga tgaatttcgg acaaaattt
//
LOCUS       DBBGSP010000003        99213 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000003 DBBGSP010000000
VERSION     DBBGSP010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 99213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 99213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.003"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(552..2165)
                     /locus_tag="ACIZE9_000240"
     CDS             complement(552..2165)
                     /locus_tag="ACIZE9_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC6092138.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2306..3214)
                     /locus_tag="ACIZE9_000241"
     CDS             complement(2306..3214)
                     /locus_tag="ACIZE9_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6092139.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3397..4521
                     /locus_tag="ACIZE9_000242"
     CDS             3397..4521
                     /locus_tag="ACIZE9_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC6092140.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4748..5665
                     /locus_tag="ACIZE9_000243"
     CDS             4748..5665
                     /locus_tag="ACIZE9_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6092141.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5658..6491
                     /locus_tag="ACIZE9_000244"
     CDS             5658..6491
                     /locus_tag="ACIZE9_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6092142.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6574..7692
                     /locus_tag="ACIZE9_000245"
     CDS             6574..7692
                     /locus_tag="ACIZE9_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGC6092143.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7713..9584
                     /locus_tag="ACIZE9_000246"
     CDS             7713..9584
                     /locus_tag="ACIZE9_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HGC6092144.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            9578..10801
                     /locus_tag="ACIZE9_000247"
     CDS             9578..10801
                     /locus_tag="ACIZE9_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGC6092145.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10887..12821)
                     /locus_tag="ACIZE9_000248"
     CDS             complement(10887..12821)
                     /locus_tag="ACIZE9_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGC6092146.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13047..13703
                     /locus_tag="ACIZE9_000249"
     CDS             13047..13703
                     /locus_tag="ACIZE9_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGC6092147.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13777..14130)
                     /locus_tag="ACIZE9_000250"
     CDS             complement(13777..14130)
                     /locus_tag="ACIZE9_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGC6092148.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14322..15251
                     /locus_tag="ACIZE9_000251"
     CDS             14322..15251
                     /locus_tag="ACIZE9_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGC6092149.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15262..16098
                     /locus_tag="ACIZE9_000252"
     CDS             15262..16098
                     /locus_tag="ACIZE9_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGC6092150.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16346..17122
                     /locus_tag="ACIZE9_000253"
     CDS             16346..17122
                     /locus_tag="ACIZE9_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HGC6092151.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17298..18041
                     /locus_tag="ACIZE9_000254"
     CDS             17298..18041
                     /locus_tag="ACIZE9_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092152.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18034..19614
                     /locus_tag="ACIZE9_000255"
     CDS             18034..19614
                     /locus_tag="ACIZE9_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HGC6092153.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19865..20344)
                     /locus_tag="ACIZE9_000256"
     CDS             complement(19865..20344)
                     /locus_tag="ACIZE9_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGC6092154.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20360..21112)
                     /locus_tag="ACIZE9_000257"
     CDS             complement(20360..21112)
                     /locus_tag="ACIZE9_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGC6092155.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21229..21299
                     /locus_tag="ACIZE9_000258"
     tRNA            21229..21299
                     /locus_tag="ACIZE9_000258"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21261..21263,aa:Gly,seq:ccc)
     gene            21660..22385
                     /locus_tag="ACIZE9_000259"
     CDS             21660..22385
                     /locus_tag="ACIZE9_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HGC6092156.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22640..22906
                     /locus_tag="ACIZE9_000260"
     CDS             22640..22906
                     /locus_tag="ACIZE9_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGC6092157.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22903..23334
                     /gene="ruvX"
                     /locus_tag="ACIZE9_000261"
     CDS             22903..23334
                     /gene="ruvX"
                     /locus_tag="ACIZE9_000261"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGC6092158.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23359..23664
                     /locus_tag="ACIZE9_000262"
     CDS             23359..23664
                     /locus_tag="ACIZE9_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGC6092159.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23745..24890)
                     /locus_tag="ACIZE9_000263"
     CDS             complement(23745..24890)
                     /locus_tag="ACIZE9_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6092160.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24951..25598)
                     /locus_tag="ACIZE9_000264"
     CDS             complement(24951..25598)
                     /locus_tag="ACIZE9_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6092161.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25792..26085
                     /locus_tag="ACIZE9_000265"
     CDS             25792..26085
                     /locus_tag="ACIZE9_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092162.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26129..26440
                     /locus_tag="ACIZE9_000266"
     CDS             26129..26440
                     /locus_tag="ACIZE9_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092163.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26437..27061
                     /locus_tag="ACIZE9_000267"
                     /pseudo
     CDS             26437..27061
                     /locus_tag="ACIZE9_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27202..27360
                     /locus_tag="ACIZE9_000268"
     CDS             27202..27360
                     /locus_tag="ACIZE9_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092164.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27361..27723
                     /locus_tag="ACIZE9_000269"
     CDS             27361..27723
                     /locus_tag="ACIZE9_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092165.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27760..28608
                     /locus_tag="ACIZE9_000270"
     CDS             27760..28608
                     /locus_tag="ACIZE9_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HGC6092166.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28598..30073
                     /locus_tag="ACIZE9_000271"
     CDS             28598..30073
                     /locus_tag="ACIZE9_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HGC6092167.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30339..30746
                     /locus_tag="ACIZE9_000272"
     CDS             30339..30746
                     /locus_tag="ACIZE9_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HGC6092168.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30749..30964
                     /locus_tag="ACIZE9_000273"
     CDS             30749..30964
                     /locus_tag="ACIZE9_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092169.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30968..31348
                     /locus_tag="ACIZE9_000274"
     CDS             30968..31348
                     /locus_tag="ACIZE9_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HGC6092170.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31482..31637
                     /locus_tag="ACIZE9_000275"
     CDS             31482..31637
                     /locus_tag="ACIZE9_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HGC6092171.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31706..32179
                     /locus_tag="ACIZE9_000276"
     CDS             31706..32179
                     /locus_tag="ACIZE9_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HGC6092172.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32176..33870
                     /locus_tag="ACIZE9_000277"
     CDS             32176..33870
                     /locus_tag="ACIZE9_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HGC6092173.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33836..34021
                     /locus_tag="ACIZE9_000278"
     CDS             33836..34021
                     /locus_tag="ACIZE9_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092174.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34025..35200
                     /locus_tag="ACIZE9_000279"
     CDS             34025..35200
                     /locus_tag="ACIZE9_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGC6092175.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35193..36716
                     /locus_tag="ACIZE9_000280"
     CDS             35193..36716
                     /locus_tag="ACIZE9_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGC6092176.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36772..37056
                     /locus_tag="ACIZE9_000281"
     CDS             36772..37056
                     /locus_tag="ACIZE9_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HGC6092177.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37043..37378
                     /locus_tag="ACIZE9_000282"
     CDS             37043..37378
                     /locus_tag="ACIZE9_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HGC6092178.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37673..38299
                     /locus_tag="ACIZE9_000283"
     CDS             37673..38299
                     /locus_tag="ACIZE9_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092179.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39041..39877
                     /locus_tag="ACIZE9_000284"
     CDS             39041..39877
                     /locus_tag="ACIZE9_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGC6092180.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLINLYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39941..40372
                     /locus_tag="ACIZE9_000285"
     CDS             39941..40372
                     /locus_tag="ACIZE9_000285"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6092181.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(40434..41756)
                     /locus_tag="ACIZE9_000286"
     CDS             complement(40434..41756)
                     /locus_tag="ACIZE9_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HGC6092182.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41910..43550)
                     /locus_tag="ACIZE9_000287"
     CDS             complement(41910..43550)
                     /locus_tag="ACIZE9_000287"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HGC6092183.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43883..44353
                     /locus_tag="ACIZE9_000288"
     CDS             43883..44353
                     /locus_tag="ACIZE9_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HGC6092184.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            44575..45678
                     /locus_tag="ACIZE9_000289"
     CDS             44575..45678
                     /locus_tag="ACIZE9_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HGC6092185.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            45962..46642
                     /locus_tag="ACIZE9_000290"
     CDS             45962..46642
                     /locus_tag="ACIZE9_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HGC6092186.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLKVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            46732..47766
                     /locus_tag="ACIZE9_000291"
     CDS             46732..47766
                     /locus_tag="ACIZE9_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HGC6092187.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            47780..48115
                     /locus_tag="ACIZE9_000292"
     CDS             47780..48115
                     /locus_tag="ACIZE9_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092188.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48099..50579
                     /locus_tag="ACIZE9_000293"
     CDS             48099..50579
                     /locus_tag="ACIZE9_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092189.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            50635..52194
                     /locus_tag="ACIZE9_000294"
     CDS             50635..52194
                     /locus_tag="ACIZE9_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092190.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52191..53555
                     /locus_tag="ACIZE9_000295"
     CDS             52191..53555
                     /locus_tag="ACIZE9_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HGC6092191.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            53726..54796
                     /locus_tag="ACIZE9_000296"
     CDS             53726..54796
                     /locus_tag="ACIZE9_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092192.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            54811..55479
                     /locus_tag="ACIZE9_000297"
     CDS             54811..55479
                     /locus_tag="ACIZE9_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092193.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55499..56077
                     /locus_tag="ACIZE9_000298"
     CDS             55499..56077
                     /locus_tag="ACIZE9_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6092194.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56478..57389
                     /locus_tag="ACIZE9_000299"
     CDS             56478..57389
                     /locus_tag="ACIZE9_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGC6092195.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(57477..58394)
                     /gene="rnhC"
                     /locus_tag="ACIZE9_000300"
     CDS             complement(57477..58394)
                     /gene="rnhC"
                     /locus_tag="ACIZE9_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGC6092196.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            58596..59033
                     /gene="zapA"
                     /locus_tag="ACIZE9_000301"
     CDS             58596..59033
                     /gene="zapA"
                     /locus_tag="ACIZE9_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGC6092197.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59092..59640
                     /locus_tag="ACIZE9_000302"
     CDS             59092..59640
                     /locus_tag="ACIZE9_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGC6092198.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            59755..62115
                     /locus_tag="ACIZE9_000303"
     CDS             59755..62115
                     /locus_tag="ACIZE9_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGC6092199.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62202..62516
                     /gene="trxA"
                     /locus_tag="ACIZE9_000304"
     CDS             62202..62516
                     /gene="trxA"
                     /locus_tag="ACIZE9_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGC6092200.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            62698..64476
                     /gene="uvrC"
                     /locus_tag="ACIZE9_000305"
     CDS             62698..64476
                     /gene="uvrC"
                     /locus_tag="ACIZE9_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGC6092201.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            64621..65520
                     /locus_tag="ACIZE9_000306"
     CDS             64621..65520
                     /locus_tag="ACIZE9_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092202.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            65513..66775
                     /locus_tag="ACIZE9_000307"
     CDS             65513..66775
                     /locus_tag="ACIZE9_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092203.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            66936..68834
                     /locus_tag="ACIZE9_000308"
     CDS             66936..68834
                     /locus_tag="ACIZE9_000308"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HGC6092204.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(69164..69883)
                     /locus_tag="ACIZE9_000309"
     CDS             complement(69164..69883)
                     /locus_tag="ACIZE9_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGC6092205.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     misc_feature    70073..70120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            70220..70552
                     /locus_tag="ACIZE9_000310"
     CDS             70220..70552
                     /locus_tag="ACIZE9_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092206.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            70539..72542
                     /locus_tag="ACIZE9_000311"
     CDS             70539..72542
                     /locus_tag="ACIZE9_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HGC6092207.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            72561..73031
                     /locus_tag="ACIZE9_000312"
     CDS             72561..73031
                     /locus_tag="ACIZE9_000312"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HGC6092208.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73052..73636
                     /locus_tag="ACIZE9_000313"
     CDS             73052..73636
                     /locus_tag="ACIZE9_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HGC6092209.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            73651..74637
                     /locus_tag="ACIZE9_000314"
     CDS             73651..74637
                     /locus_tag="ACIZE9_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HGC6092210.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            74627..74938
                     /locus_tag="ACIZE9_000315"
     CDS             74627..74938
                     /locus_tag="ACIZE9_000315"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HGC6092211.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            74960..76741
                     /locus_tag="ACIZE9_000316"
     CDS             74960..76741
                     /locus_tag="ACIZE9_000316"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HGC6092212.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            76734..78110
                     /locus_tag="ACIZE9_000317"
     CDS             76734..78110
                     /locus_tag="ACIZE9_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HGC6092213.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78117..78752
                     /locus_tag="ACIZE9_000318"
     CDS             78117..78752
                     /locus_tag="ACIZE9_000318"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HGC6092214.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            78782..80137
                     /locus_tag="ACIZE9_000319"
     CDS             78782..80137
                     /locus_tag="ACIZE9_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGC6092215.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80329..81723)
                     /locus_tag="ACIZE9_000320"
     CDS             complement(80329..81723)
                     /locus_tag="ACIZE9_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGC6092216.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            81815..82786
                     /locus_tag="ACIZE9_000321"
     CDS             81815..82786
                     /locus_tag="ACIZE9_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HGC6092217.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            82783..83565
                     /locus_tag="ACIZE9_000322"
     CDS             82783..83565
                     /locus_tag="ACIZE9_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HGC6092218.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(83734..84105)
                     /locus_tag="ACIZE9_000323"
     CDS             complement(83734..84105)
                     /locus_tag="ACIZE9_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6092219.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84239..84682
                     /locus_tag="ACIZE9_000324"
     CDS             84239..84682
                     /locus_tag="ACIZE9_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGC6092220.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(84725..85534)
                     /gene="yidA"
                     /locus_tag="ACIZE9_000325"
     CDS             complement(84725..85534)
                     /gene="yidA"
                     /locus_tag="ACIZE9_000325"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGC6092221.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(85553..86920)
                     /locus_tag="ACIZE9_000326"
     CDS             complement(85553..86920)
                     /locus_tag="ACIZE9_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGC6092222.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(86904..87734)
                     /locus_tag="ACIZE9_000327"
     CDS             complement(86904..87734)
                     /locus_tag="ACIZE9_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HGC6092223.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            87897..88334
                     /locus_tag="ACIZE9_000328"
     CDS             87897..88334
                     /locus_tag="ACIZE9_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGC6092224.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88410..89030
                     /gene="rpoE"
                     /locus_tag="ACIZE9_000329"
     CDS             88410..89030
                     /gene="rpoE"
                     /locus_tag="ACIZE9_000329"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGC6092225.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89219..89725
                     /locus_tag="ACIZE9_000330"
     CDS             89219..89725
                     /locus_tag="ACIZE9_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HGC6092226.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            89742..90641
                     /locus_tag="ACIZE9_000331"
     CDS             89742..90641
                     /locus_tag="ACIZE9_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HGC6092227.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            90728..91612
                     /locus_tag="ACIZE9_000332"
     CDS             90728..91612
                     /locus_tag="ACIZE9_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGC6092228.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(91804..91875)
                     /locus_tag="ACIZE9_000333"
     tRNA            complement(91804..91875)
                     /locus_tag="ACIZE9_000333"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(91840..91842),aa:Arg,seq:ccg)
     gene            91935..93269
                     /gene="rpoN"
                     /locus_tag="ACIZE9_000334"
     CDS             91935..93269
                     /gene="rpoN"
                     /locus_tag="ACIZE9_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HGC6092229.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93418..94509
                     /locus_tag="ACIZE9_000335"
     CDS             93418..94509
                     /locus_tag="ACIZE9_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HGC6092230.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            94550..95551
                     /gene="gap"
                     /locus_tag="ACIZE9_000336"
     CDS             94550..95551
                     /gene="gap"
                     /locus_tag="ACIZE9_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGC6092231.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            95661..96851
                     /gene="pgk"
                     /locus_tag="ACIZE9_000337"
     CDS             95661..96851
                     /gene="pgk"
                     /locus_tag="ACIZE9_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGC6092232.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            96955..97710
                     /gene="tpiA"
                     /locus_tag="ACIZE9_000338"
     CDS             96955..97710
                     /gene="tpiA"
                     /locus_tag="ACIZE9_000338"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGC6092233.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            97826..99124
                     /gene="eno"
                     /locus_tag="ACIZE9_000339"
     CDS             97826..99124
                     /gene="eno"
                     /locus_tag="ACIZE9_000339"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HGC6092234.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        32892 a        16939 c        20460 g        28922 t
ORIGIN      
        1 ttaaataaat aggaacaaaa aaattaaatt atttaataca cacattaggg atcattcatt
       61 gaaggattag aagacaacga ggatggcgaa aaatatgatt acaatagaaa agtcgttcta
      121 aaccaatcag ttcctagtat cacacaacgc aagccagtcg atttggtgag attagaggag
      181 tgaaagcaaa ctttattata taagaaaaaa tattcgaaag ggatgctagt ttaggtacta
      241 gtgctgatag attaatatga tgcctcgtaa tattaggcgt agttactcta gagacatcac
      301 tatggactat gatttgtctc agagtcacaa catgtttttt tatgaaaaga aacagctaaa
      361 ataattaaat tgcgcaatgt ttaaactttc ttaaactata acctaataaa tgtgaagaaa
      421 taatgcacaa tttcttcaca tttatcttct attctatata cataccaacc aacaacccta
      481 tatacttttt catttttact cctcaagtaa aaataactcc tagaccgcgg ctacccaccg
      541 cggtcgtttt tttattcttc aatcaaaatc gctttgatac ccaaacctgc caagattcgg
      601 gcagaagtat aagtattcaa tcctcttctg aaagtaatgt aaactttttt atcttttggg
      661 atttcattga ttcgatctcg taactcattc attggaatat tttttgttgc cgagatactg
      721 ccagaaggtg ctttattagg ttcacgtata tctaaaaaga acgcttcttt caaatcgttt
      781 tcgggtatat cacttgcttt gatcgtttct acgatattcg tcatttgatt gattgcgaca
      841 taaccagcta tattcaacgg gtcacgggta gtagaatacg gtggagagta aggcaactcc
      901 aaatcaggca aatcaaagac tgtcaagttt ccggtgattg ctacagaaag ttctcccatc
      961 cgtttatcga cacctttttc tccaaatgct tgtccaccta aaatacgacc gctatctgca
     1021 tcaaaaatca gctttagatt taatcttgta gcttctggat agaaataggc atggtcaaag
     1081 ggagtgataa aaacagtttt ataatttgtt atgcctgatg cttttaattc atgttctgtc
     1141 attcccgcat aacttgctgt atgatcaaag atttttgcga cacctgcacc aatatatccg
     1201 cgatagcgca taggcgtacc atttaaaata tctgccagca tatgtccttg acgattggcc
     1261 gcactggaaa gcatactttg gatcggctga ccagtcacta cactagtcgt ttcgataata
     1321 tcgccaatcg catagatgtc cggcagattg gtttgtaact ggtcatcaac aatgatctga
     1381 cctgtatctg ataattgtat gccggttgct ttcaccactt cattcttcgg agaaacacca
     1441 acagcaaaaa ttagcatatc agcagaaagg acggagccat ctgataatac tatttctcga
     1501 cctttatcac ggatctcagt aactcttgtt tctaaatgaa cggctaatcc ttctttcagc
     1561 aatttgtcat aaactaaatt agcaatttct ggatcataag ggaaagcgac ttgtggcaat
     1621 tgatcgatta aagtcacgtc taagccgcga tgcttgaaat tctcagctaa ttccagaccc
     1681 ataacacctg caccaagaat gacgacatgt tgtggatttt tttcttcaag gaacgatttg
     1741 attcgatccg catccgtcac actacggagg acaaagccgt tttctgcttc aaaaactccg
     1801 ggaatatccg gataatctgg tctagcacca gaagagatga tcaacttatc gtaatctgtt
     1861 tttatttctt catttgtgga taggtcttta actgttaatc gcttagtaga aggatcgatt
     1921 gctgttactt cgtgtttagt aaagacatcg atgttgtttt ttgttttcaa tatttctggt
     1981 gtacgttcga tcagcgagtc acggtcagtg atcacacctc ctaaataata aggcaaagca
     2041 caacttgcat aagaaatatt ttctccgcgt tcatagataa tgatttcgtg cgcttcattc
     2101 aatcgacgga aacgagtggc aaatgaagga ccgccagcta caccgccaat gacaacaact
     2161 ttcataaaaa catctccttt tctacgttga tcgtactatg ttatggtaaa aaacagcaaa
     2221 taattgtgcc ggaaaattat tgtttatttt gaatagacag aaaatataga gaaataattt
     2281 gtggataaaa cctaaaaatt tttttctatt ttaaggatag ataatacttt gaaggggata
     2341 accctgtata ttttttaaaa gctgaagaaa aatgatggat cgaatgaaat cctaatatat
     2401 ctgcaatttc tgtataggtt aattcatttt ctagcacgag acgttttgct ttttccattt
     2461 ttagttcttt aaaatagcta ataacacttt ttccattcac ttttctaaaa tgttttttta
     2521 agctggctgg actgataaaa aaaatttggg ctaattgttc aagcaaaaaa ttttctgaaa
     2581 gatgttcttc taaatatcgt atgattggat caactaattc atctgaataa agaatatgct
     2641 tttttttagg aatgactttc tcatttgaag gtattgtcaa taaagcaagt tcctgttgat
     2701 aatgccttgg taaggaagac aattgaattt tttgcagaca ataagtaact aataaggaaa
     2761 gcaaatgaat gctcatctgt tggcatagta tgaaaaaaga attgatttcc tgatcatagg
     2821 aaatagctgg cttactatgt tttagataat caattttgaa ctgttcattt ttcagaaaag
     2881 taatgataga tgttatttct tgatctatag aaaaagattg tcccgtaata tgtgctaata
     2941 attgctcatc aaaataaaac tggataatga taaaagtttg tgtttccttt tgagtagaaa
     3001 agatttggac ttcttgctgt ttatcaatga ataaaaggga aggattatct agttctatag
     3061 atttatgtgc aaattcagca tataaattag cgctttcatt tattagtagt cgaaaatagg
     3121 gagcagcaga taaatgaaga tgggtatcta tggaataggt tagtgttttt ttgacaagat
     3181 tggaggattg gttgtttgtt aacaaaagaa ccactttcct ttctcttttt atataaaaag
     3241 ctttctattt ataattaatg actattataa caaaaatgaa aagccaaaac gacaagtaaa
     3301 atattttttt atataaatat ttgtgttact aattccgtta atatacataa gtgaaagcgt
     3361 tttatataag aacttgaaaa gaaagaaggg atagacatga aaaaaagata caaattggtg
     3421 atagctttgc taaacattac cctattattc agcttaagtg catgtggaaa aactaacgaa
     3481 gaagtaacag caaacatcgc agatccaatg ataaaaaaag ccactacatt agaagtatat
     3541 gtcgcaaacg gcaaactgac aaactatgtt gaaaatgctg caaaaatcta taaccgcaaa
     3601 actggagcaa atattgactt aaaaattgtg aatgtagctt cgggaacagc aacagtacaa
     3661 atgatcaccc caaaattggt aacacacgaa gatatgccgg atattatctc catggcagac
     3721 acttcagcag caggtgtgct ggaaaaattt caagatgctt tttatagtgc tgatgaatat
     3781 ggattttatg acaaatatgg cgatcagttt tatgatcaaa aattgaatat tttgcgtcaa
     3841 caaacgagta atgaaacgat tattccttgg gctagtgatt ttaccccagc actttgttat
     3901 tatcaaccaa aaaaatttgc tgaaataggt gtagattttg aagaaatcag ttcttgggaa
     3961 gaatatatcc aggtggcaaa agcattaaaa gaaaaaactg gtagttttgg aattgccttg
     4021 ccagaatctg gggaccaaga attgtttatc aacatgctag cccagcagaa tcaatctttg
     4081 cttgatgaag aaggaaatat ccgtctgaat actaaagaag cgaaacatgc tgcaaagtta
     4141 atcaaagaaa tgatcgactc agatattgta catttctacg gtgcacaaga tgctgagaaa
     4201 gcatttcaag aatctgcaat gtttgttgct ggcggctggt atgctacgaa tatgtctttg
     4261 aattttcctg atgcatctga caaatggcgc atggctccac tgattccttt ttcaaaagaa
     4321 aatccaggaa aaggtgcagt atcaggagga tcaagttttt atgtccctaa agatgcaaaa
     4381 aatccacaag tggcacaaca atttcttaca tttatgctga cagatgaaga atgcttagcc
     4441 aacgcactgg agctgggcgt ggctacatct aactcattgg cctatcaaac agaagcagct
     4501 gagaaaaagt ttgactacta aggaggacaa aaatactatg aactattgaa taaaatcaat
     4561 gaaaatacat caaatactgt tttaccagcc acttattcag atgctacgtc ttatttgact
     4621 accgctgcat ataactattg gcaaacaggt gattttgaaa attcatatct aaaagaagca
     4681 gaaaattttg ctcataagta cggcgtaaaa ttaactggtg attaaaaaat attaggagga
     4741 cttaacgatg atgcaatctt cgttaccaag caagacaata aagaacagca agaaaaaagc
     4801 aacagatacg tctcataaaa aaagtgctta tggattggtc acaccttttg ttattttctt
     4861 tattgtgacg attttgattc ccatcattat ctcgtttgct tttagtttta tgaaaattgg
     4921 ctactcattt gaatttgttg gatttgacaa ttatctagct atcttccgag atccattgtt
     4981 tattaaatct tacacgaatg ttttgattat catggcagga tcaattccaa taacgatgct
     5041 attagctatt tactttgctg ttttattgaa ttcagcacag ttaaaaggaa aaggattttt
     5101 tagaactgtc tattatattc caaccattac atcaacggtg gctgtagctt ccgtattcat
     5161 gacttttttc aatccgactg ggttattcaa tggatttttg aatgcgctag gaattaacgg
     5221 tgtacagtgg ttaacaaatc ctttttggat acgaatatca atgatcatca cgatgatttg
     5281 gcttagtgta ggatataaca ctattttatt tttagctggt cttcaaggga tttctaaaga
     5341 gatatacgaa agtgctgaaa tagatggagc atcgaaattt cggcaattct ttttattaac
     5401 gatccccatg ctaaagccaa tcattttaat ggccacagtt ttagccacta tcaatggctt
     5461 gggtaatttc aatatcccaa atatattctt tgggacttcc aatggaccag aaaattcagc
     5521 tttggtcgta ggagtcaatt tatataaaac aagttttgaa atggttgatt ttggaaaagc
     5581 ctctgctatt gcctggacga tggtgtttgt atctgttata ttatcggcta ttcaatttaa
     5641 attcggaggt gataaaaatg actaaacaaa agatacaaag cagaattttt acgtacgtca
     5701 ttattgtgtt tggtgcctta atatttttga tgccatattt atatatgatt gtagcttcaa
     5761 cgcaaagtaa tcaagaaatt ttaagtggcg gaatcaattt caagtttggg gatatgctat
     5821 taaaaaactg gcaagccatc atggcgagat ataattatcc cttgattatt tggaattcga
     5881 ttgttattgc tgtaatcagt acagttttag ctacagccag ttctacaatg gcgggttatg
     5941 cattagcaaa gtatcgtttt atggggaata aactgttgtt caatacagtt atgctatcta
     6001 ggatggtgcc tttttttacc acattgattc ctttatttta cattatgagt cgtttaggat
     6061 tatcgaatac ttatgcaggt gtgatcatcc cttcgattgc cagtacaact tcagtgttta
     6121 tgatgcgaca atatagcagt caatttccta cagcactgat ggaggctgcc agaatcgatg
     6181 gtgccaatga gtgggtgatt tttacgaaaa tcgctgtacc gattttatca cctacgatta
     6241 ttactagtgg tttacttatc tttatgggaa gttggaatca atatctattt ccattagtca
     6301 tgctttcaga taaagataaa tatacggttc ccttaattat caaaaatatg acggtttcta
     6361 gtacaggtga gccaattaat tatggcgcaa ttatgctaat tttagcaact tcagtgatcc
     6421 caatggtctt gatttatgtg tgggcgcagt ctaaatttaa ggagaatgac attggagctg
     6481 caaataagta aaaaaaataa cgaatgttaa ccatctagtt cgttctagga gcaactccac
     6541 attcataaaa attaaaagaa tggcgggata tccatgaatg aacagacgaa ggaatggtca
     6601 agaaaaattt tgaatgtagc ttctgaaaag atagatgcgg aattagacag aatggggaat
     6661 aaaattccat atatttctta caacggaaaa tatacagacg taataaagga cagaggaatc
     6721 gactggtgga ccaatggttt ttggagtggt attttatggc agctctttca caagacaaaa
     6781 cgagaaaagt tcaaagaggc agcaatacaa caagaacaat tattagaatc tgccctgtac
     6841 catttttcag acgttcatca tgatgtaggt tttttattct taccatcggc tattgcacat
     6901 tatcaacagt ctcaaaacaa acatagtcga caactagggt tacatgcagc tacggtactt
     6961 gctggacgct ataatatttc agggaactat ttagtagcat ggaatgacca taaacctggt
     7021 tggatgatta ttgatagtat gatgaattta ccattactgt attgggcttc gagggaaact
     7081 ggtgatccga ggttctctaa aattgctcgg cagcatgcag atacaacagc taagtatcta
     7141 gtgaggaaag atggatcaac cgggcatatc gcagaatttg atgcagaatc agggaaatat
     7201 attcggttac ttggcgggca aggatacaat gagaattctt gttggagcag aggaaatgca
     7261 tgggctttat atggattcgc gttaagttat cgttacacaa aaaatccgta ctatctagct
     7321 atagcagaaa agatagcagt aaattttatt cagaaaatcg aaaaaactgg ttatattcct
     7381 ctcattgatt ttgctgtaaa agattcgaat attgatacca gtgctggagt atgcgctgca
     7441 tgcggtcttc tggaattagc aggatatgtt tcctctgtac gatcaaaaat gtatcatgaa
     7501 gctgctatca atatactcca aaagacagaa aagcactatg caaattggaa tatggatgaa
     7561 gatgggatca ttggaggcgg agcagaagca taccatagag aactgactta taatgtgcca
     7621 ctgatctatt ctgattattt ttttattgaa ggcttacttc gattagaaca gtcggaatta
     7681 gctatttggt agtaaaaaga ggagaaaata caatgaaaca tccagtacca ctattaagga
     7741 ccagacagga ttactttgac ttatttaaaa agataaatca accactccag ccgttttatc
     7801 gagcaagtgg cgcacaaatt gattatatac atcaaggggt aggatatgga aataaaattg
     7861 caggaatgga aggattctct cgggttttat ggggagcggg gcccgcaatt gaccaattag
     7921 atgaacgatg gttgaaatta attctatcag gaataaaagc tggaacagat ccttcccatc
     7981 ccgattattg gggagaaata catgaaagag accagcgtat ggtagaaatg cccgcaatgt
     8041 tattagcgtt atatcatcat gaacaattat tatggaaaaa attagataca ggagaaaaaa
     8101 gccagattat tcattggttc tcgcaaattt ttgaatatga atgtgcagat ggtaattggc
     8161 aattttttaa gataattgtc ggaacaatta tccaaaaatt tggttatcca gttaaagaat
     8221 cagcactgaa agaagcattt gataatatag aaaattgtta tcttcaaaat ggctggtatc
     8281 gagacagttc aagaggtcgc caagattatt ataatccttt tgcatttcat tattatggtt
     8341 tgatttatag cgtactagaa ccagaaaagc ccattagcca gatatataag aaccgagcta
     8401 ttgatttttc tagagactat attcattttt ttgcggaaga tggtgcaaat gtgccttttg
     8461 gtcgaagcat gatttatcgt tttgcagttt caagcttttg gtcagctatg ttgtgggccg
     8521 atcttttgcc ttttaaatta ggtgaaatca aggggttagt caatcggaat ataagatggt
     8581 ggatgcaaaa agaaatattt gatgaaaaag gtatcctgaa tattggttat acctaccctc
     8641 aattgacatt gactgaaccc tataatagta cgttatctcc attatggctg aataagattt
     8701 ttttattgtt ggcgctacct gaagaccatg agtattggac ggctaaagaa atgcctatgc
     8761 ctattcgtga aggaactaaa cttctttcag aagccaattt gctcatacaa catgataatg
     8821 gacatacatt ttttttgaat gcgggacaat tagggccaaa tttccataca ttgaccaatg
     8881 aaaaatattt aaaatttgct tattctagtc aatttggttt ttcgataccg cgagcgaatc
     8941 aattgaaagc agaaatggca atggattcaa tgctagggat tcagcgagcg gacacatata
     9001 tcacgaccag ttttaagaat gagagcatca aaacctatgg acagttcatc gttcgaaata
     9061 atgtacgaga cattgtatgt aagaaagagg tacttgcctc tacatgggaa cctactttac
     9121 aggcaaaaat cagaacttgg cttattcctt ttgaaggctg gcagattcgc gtacacaaag
     9181 tagaattaga tacagaatat gttctatatg agacagggtt tgctattgaa tgttctcctg
     9241 agaaagaagg aataatcata gaagaagaca aggaaaacta tagggtgagt gaagctggct
     9301 tttcaggtat tatctgttta agtgacgata ctattaaacg aaaatccaca gctattatgg
     9361 gtttgcccaa tacaaacttg atgacatggg aaaacacttt tattcctgga ttagagggta
     9421 catttggaaa aggaacccat tggctcggaa caggagtggt tgctcatcaa gatcgggatt
     9481 atagtttaga agtatggaac aatcgtccca aaattgattt tgatgggaca accgggctaa
     9541 ctatccaaaa taaaaacaat aaaaaaagac taaaattatg ctaaaggctg gtggggaaat
     9601 gcttgataaa gtgatgtttg aagagataat acatccagaa aaatggataa atgaatgtta
     9661 taaagaatta atggaaaaag aatggaataa tgagatcgag cgttgtcgca gacacacgga
     9721 gaggttaatc aaacgtatca gtaacagtca gtatcaattc ccaagcgagt gtcctataaa
     9781 aggacgttat ccattaagag acaatattgg ttggacagaa ggattttgga caggaattaa
     9841 ttggttgtta tttgagaaga cgggtgatcc tttatttcaa caaacagctg aaaaagcaga
     9901 tatagatttt atccacagga ttgactgtca aattatcact aatcatcacg atcttggttt
     9961 tttgtattct ttatcaaccg tagcagatta taaaataacg ggaaatcgaa aaatgaagga
    10021 agcttcaatt gatgctgcag aaacattact tcagcgtttt tgggagaagg caggagttat
    10081 acaagcttgg ggagatccta gtgatccttc acaacaaggt agaatgatca tggattgttg
    10141 catgaatctt ccattattgt attgggcgag tgaagaaact ggaaatcaaa aatataaaaa
    10201 agctgctcag gctcatattc aaaatgcagc agattattta gtaagagaag atggttcaac
    10261 ttatcataca ttttatatgg atgtcaaaga tggaaaacca agatatggaa gtacgcatca
    10321 aggttatagt gataattcct gttgggctag aggccaagca tgggggattt acggttttgc
    10381 attaagttat cgttatttga aagaacaaaa atattttgat ttaagcaaaa tattagccaa
    10441 ttattttatg aatcggttgc cagaagatac catttgttat tgggatttga tctttgatga
    10501 ttctagcaga gaagaaaaag atacatctag tatggtgatc atggtttgtg gattattaga
    10561 attaatagaa tcaggtctat tagacaaaac agaaaagaac ttataccagt ctgctgtttg
    10621 gaaaattatg cgacaattga aagaaagata tgctacaacg gaagaagaag atggcttttt
    10681 aacacagtct gtttataata agcccaaaaa taatggggta aatacacctt gtatttgggg
    10741 tgattactat tatttagaag ctttagtgag aatgactagt aattggtctt cttattggtg
    10801 aaaaaggtaa atatggaatt tttgtttgat aaaataaaaa aagaaaaacc aaaacagcat
    10861 gaatggtttc tgttttggtt ttttcgttaa ttttcatatt cttctaattc caagcttagt
    10921 tcttcccatt ccgtcaattt tgtttcttga tcttgtctag cagcttctaa atcttggttc
    10981 agctcattga gttttacgtg atcttccagg ttttctggcg cgaccatttc ttgttccaac
    11041 tgatcgatcc attcatcgat ccgcgccatt tcttcttcaa cctgagtaat ttttcgttga
    11101 aggctacgga taagcttttg ctgttctttg ctttggtaat aatcagattt gttcgtggga
    11161 gcaggagcag attctggctc atcttgtgcc aacaattcgg cgatttcttc ttcttcctgc
    11221 tttttctcta aataataatc atagtctcct agatagactt tgctgccatt ttcagagagt
    11281 tcgacgactt ttgtcgcgat ccgattgatg aaatatcggt catgggaaac aaaaagcagt
    11341 gtgccgtcat aatcgatcaa tgcattttct aatacttctt tgttgtcaat atctaaatgg
    11401 tttgttggtt catccaaaat caaaaaattt tctttgttca tcgctaactt ggctaaagca
    11461 acccgtgctt tttcaccgcc acttagcaga gggattggtt tttctacatc ttcgccagaa
    11521 aataagaaag cacctaaagc acttcggatc tctttttctg gagtggtagg atgctcatcc
    11581 cacaattctg ctaggatcgt cttgtttgta tgcagatcag cttgaccttg atcgtaatag
    11641 ccgatggtga catttgtccc tagcgtttct tttccacgga taaaagggat ctggtgaatg
    11701 attgatttca gcaacgtcga tttcccgata ccattcggac ctactagagc aatcgcttct
    11761 tgacgacgga tatctagatt gattggttca gataaggtga cattatcata tccgatagcg
    11821 gcatcttcga tttgcaagac tacatttcca gaaggctttt ctatactgaa tagaaagttt
    11881 gcttgttttt catccccttg aggacgatcc agccggtcca ttttttctaa tgtctttctg
    11941 cggctttgcg ctcgttttgt ggtagaggcg cgaacaaggt tccgagcaac gaagtcttct
    12001 aatttatgga tttctgtttg ctgcttttca taagccttcc attcacttgc taactgttct
    12061 gctttcaaat ctagatattt cgaatagtta cctttgtaat ggcgcatttt tcttctgctt
    12121 aattcataga cttcattgac tactttatct aaaaaataac ggtcatggga aacaatcaat
    12181 aatgcaccag tatagctttg cagataattc tcaagccagg aaagtgtctc gatatctaaa
    12241 tggttcgttg gttcatctag aatcaaaatg tcagggtgtt gcaaaagcat gcgagctaaa
    12301 gctaaacgtg tgcgctgtcc gcctgataaa gtatcgattt tctgatcata aaatgaagaa
    12361 tcgaatttaa acccatgcaa tacggaacga atttcatttt cataaccata gccgtttcga
    12421 tctgaaaaat cgtgttgcag ccggtcgtat tcttttaaat aagaactata agcaggtgtg
    12481 tctggcgtac cttcgctaat gaaaatctct agctcgcgca tccgctcttc catttgtcta
    12541 acttgttcaa aagctttcag catctcgttc caaactgttt cattggaatc aagtcctgtg
    12601 tcctgagcga ggtatccgag agtcgctgtt ttatttttag cgatctttcc ttcatcaggt
    12661 gcttcaattc cagcaatgat ctttaataaa gtcgattttc cagcgccatt tctgccaact
    12721 aaagcgacac gagcgcctgt actgatttct aaatgtatgt tttcaaataa gacttctgca
    12781 ccaaaatggc gagcaatctg attggcttgt aataatatca tggaatcctc ttttctactt
    12841 tgtgaattct cctcaaataa aaaactattt ttcaattagt agtctaccat aaattccatt
    12901 atactgcgag atttgcagaa atgataaata aatgaataaa gaataaaatt tcacaatatc
    12961 tgagcaatgg aattgatttt ttcctataaa tactgctatg atggagaaat caaagatgta
    13021 attagacaat acgtggaggt catttcgtga aagatcatat tattccaaag gcgacagcta
    13081 aaagactgcc tttgtattat cgctatttaa ggattttaaa taatgctgga aagaaaaaag
    13141 tgtcttcaac tgaattaagt gaagccgttc aagtagatag tgcaacgatc cgtcgagatt
    13201 tttcttattt tggcgaatta ggaaaacgtg ggtatggtta tgatgtagaa gatcttatgc
    13261 acttttttgc aaagacatta aacgacgatc aattgacaaa tgttgcgctg atcggtgtag
    13321 ggaacttggg aagtgcttta ctaaaataca aattccatca aagtaatagc atacgtatca
    13381 gttgtgcttt tgatgtgaat gaggaaatcg ttgggcgcat cgtagacggt atccccgttt
    13441 atccaatgga agatatgtca gaacaaatca agatccaaca aatcgaagta gcaattttaa
    13501 cgatacccgc tgaaagagca caagaagtag tcaatcagtt aacggaagca ggaatcaaag
    13561 gaatcttgaa ctttaccgct gctcgattga atgctccgtc agatgtattg atccaaaatg
    13621 ttgatttgac gaatgaattg caaaccttga tctatttctt gcattctgac gcaaatgcgc
    13681 attccgaaaa tacagcagaa taaaaataaa aagcgattga acaaatgaag gcaaaacttt
    13741 cacttgttca atcgcttttt tctgtttgga caacgattat tttgttcgga agatttcttc
    13801 ataagaaagg gaatcatctt ctgctgtcag ttcatctagt agataacgga tttttttaaa
    13861 gtcgatgaac cgtgcttgcc gaaagacttc ttttccttga tgaaaaatca ggacaactgg
    13921 cgcagtcagc acttcaaatt tactagctac ttctggtgtt tcaaatgcat ccaaatgaag
    13981 tgccggaata tcataatgtg tgagaagttc ctctagtcgt ggacgaacag cgtgacaaac
    14041 actgcaatta ggcatcgaaa gataaatgac ggcaacggat gactgttgca gtatgtcttg
    14101 aacttcagtc aagttagtgg tttgtttcat ttttattctc ccttttatga tagaagtgat
    14161 atgtatgaga ccttaattta atgggaataa cagaaaaagt caattgaagt gctttggtaa
    14221 aaaataagag ttgtgtaaaa atttacagag caacttgttt tttttgaata aaagcgtata
    14281 tttgcaaagc gaatgaacta gaaataaaaa ggaggaaact catgttttct tttattccaa
    14341 attcggtttt gcagatgagt acgattttct tatcgatcgt tattgaagca ttacctttcg
    14401 tattattagg ctgtcttatc tcaggcgcct tacaagtatt tttgacccca gaacgtgtga
    14461 agagatggct tcctgaaaat cgtatcttct ctatttttac tggttcgatc ttaggatttt
    14521 tctttccttc atgtgaatgc ggcatcgtac cgatcgttca tcaatttgtt aaaaaaggcg
    14581 taccagttca cacagcgttt gcttttatgc tgactgctcc gatcatcaat ccaatcgtga
    14641 ttttttccac ttttatcgca tttggcaatt cttggcagat ggcaagctgg cgggtgatag
    14701 gcagcttttt tgttgccctt gtgattggtg tctggcttgc ctattttcaa aaagacgctg
    14761 tattgaaaga aaaaatcacg tctaaagtag cagaaaatca ccatcatcat gtccatgaag
    14821 aagaacaaag tgagaagaat gaaccaaaaa atcagctgat ccatcaaact gggcatgtgt
    14881 tgacacattc aatcgacgaa ttttttgata caggtcgtta tttgatcatt ggcggattaa
    14941 tcgcagctgc gatgcagact tatttaccaa ctagaattat gctaacgctc ggctcaacaa
    15001 agattttagc cattatcatc atgctgttat tggcctttac gatgtctctt tgctcagaag
    15061 cagatgcgtt tataggatct tctttgttaa gtctgttcgg cacagcacct gtagctgcct
    15121 ttttggtctt tggcccaatg gtcgatatca aaaatctact gatgatgaaa cgatatttta
    15181 caggacgctt tattttatcg ctgatcggac tgattgccct tagcgttatt ggattcacat
    15241 tatttattta ggagggaaaa tatgctgcgg tttttgattt tatctgggta tttcgaattg
    15301 atgatgtact tgcaagtttc tggcaaactc gatcaatata tcaatgtcca ttatcgctac
    15361 ttagctattc tttcaatgat tttatctgct cttttggctt tagttcagct gtatttgtgg
    15421 gtcaaaaacg gaaaagcaga agaaaaggca cacgagcacg atcatgacca tgggttgtca
    15481 aaaccttatc aacgtggaat cgcttatgta ctgctagctt tgccagtaat cgtggggacg
    15541 ttgtttccaa cagttagtct cgacactacg atcgtagaag ccaaaggatt taatttccca
    15601 gtaagtaaag aatcagtagg ggatccggag atgcagacac aatacttaaa gccggatacc
    15661 agtatttatt tcaacaaatc agactactta gaccaaatga atgagttgaa agaaaagtat
    15721 ggggataagc aaactatcaa gatcacagat gaaaactatt tagaagttat ggagctaatt
    15781 tataattacc ctagcgaatt cattggcaaa aaaatcagct atgaaggatt tgtttaccaa
    15841 acaccgaacg atagcaatac agatatcttc ttgttccgat tcggcattat ccattgtgtg
    15901 gcagattcag gagtctttgg tttgttgacg catatgccgg aaggagtaac ggttaaaaat
    15961 gatgaatggt ataaaataga aggaaccatc caatcagact attatcaacc attcaagcgt
    16021 gaaatcccat ctgtagttgt tacaaacgct gagaaagtct ctgctccgaa aaatcagtat
    16081 gtgtatcgtt ctttttaaaa gaacaaaata aataaacata gctcagacag ctgacacgca
    16141 aggacgtcgg ttgtctggct ttttttgcat gatgtattca tttgtttgat atttatttta
    16201 gaagcagcat cctgaaagta tttgatatcg gtttcaaagg tgttggaaaa gattgtgaag
    16261 agaattacaa tttattccta acatgtatgt tgaaaagttg tatgaaatga ttttgatagt
    16321 aaaatatcga gtggaggtac tttttatggt aacgcgtata tttattttgg atgatagttt
    16381 ggtttttgaa aaaatgctag tagaaatttt ggaagaatcc agaattttat taagtccttg
    16441 gaaatttgag atcgttcagg gattgaacgt tatacaattt gttgaattca ttaaaaataa
    16501 tgaaatctat tcctcagata tttttttcct agacatcgat ttgaacgcct attatagcgg
    16561 tatcgaacta ggcgaaatgc ttagagaaaa gaatgaaaag tgtaaaattg tttatctaac
    16621 gtctcatccg aataaagcaa taactgttat taatcgaaag attacgccta gtggttattt
    16681 gataaaagaa ttcacttatg aaaaaaataa aaaaagcatc caaagttact tattgaaaga
    16741 aaaagaaaac tatcctgttc aacatgctac gaaaaaaagg tggacaactg tccgttatgg
    16801 taatagcgat cactatatcc attacgatga aatcctttat ctaatgagca tgccaggtta
    16861 taaaaataaa ataggcctag tattgaaaga tgaagagatt ctcgtaaacg gcacaattaa
    16921 aaaatataaa aaatcactcg aatatgagta tttatgtaaa gatttaaaag cttatatcat
    16981 taatactgaa aacattacat ctattagcag agtaaacgaa atagtaacat ttgcaaatgg
    17041 agaacaacta gagatgggaa agagaagtat tgataaacta aagaatttta tgcaagaaaa
    17101 gatagaaaat gaatcatttt aaagaaaaca aagactcata tcttacctgt tagaagagtg
    17161 ttttcctgta gaagagaaca acccaagtag cagcctagtc gtttctatcc ttttttgtta
    17221 tgcactcttt ttgacattta ctccaccaat aacgaagggt acaataaaaa gtaataacaa
    17281 acaaaaggag tacagaaatg attgaattca tcaatgtaag taaaagttac gggaaaaaac
    17341 aagcattaaa agacttgtct ctctcgataa gacaagggga aatttttgga tttttaggac
    17401 ataatggtgc cggaaaatca actacgatta aaagtttagt tagtattatt gaaccatcat
    17461 cgggaacgat tttagtagat ggaatgaaat tgacggaaaa tcgattgagt atcaaacaaa
    17521 aaatcggtta tgtgcctgat tccccagata tttttttaca attgacggct ggagaatatt
    17581 gggacttgat ttcagctgcc tatgaattag acacacaaaa aaaagaaaag cgtttagcag
    17641 aattgacagc gctttttgat atgtatagtc atcaaaatga aacaatcgca agtttttcac
    17701 atggaatgcg tcaaaaaacg attttgatcg gcacgttgct gccagatcca gatatttggg
    17761 tattggatga acctttgcaa ggacttgatc ctcaagcagc atttgatttg aaagaaatga
    17821 tgaaggctca tgccgcaaaa ggaaaaacag tcattttttc tacacatgta ttggataccg
    17881 cacaacagtt atgcgataaa ctggctattt tgaagaaagg tgaattgatt tatcaggggg
    17941 cagttagtga attattgaat ggctcacctg atgaaacgct agaaaagatt tatttgaaaa
    18001 tggctggaag gcaagcgaca ggagatggac cgtatgtata agcgacaatt attagaatta
    18061 attcgagtta atcttttata tgttaatcca cagctcacga ataaagcaag agagaaagga
    18121 aaaaagggaa agcgattaac tatctatctt ttgtctcaaa atcttttttc agggctgatt
    18181 tttttactga tttacggatt tgctatgttt gctatgaact ttgttaaatt gccaggtttc
    18241 tttacttatt acgtggcact ttttggtatg ttaggtttaa ctcaaagtat atcagtcatt
    18301 tataatatct tttttgaagg aaatgacctg caagtatttt tgcctctgcc ttttggacaa
    18361 gaacaggttt tttcagcaaa gattttggta gttgctttga ccatcattcc ttttgttttt
    18421 ccgcttctag tcatgtttat tttaaccgga tggcgagctg atctagggat tttgcttact
    18481 atcattatct caatcctttt gttttctcta tttttgatta ttcttttttg tctggctagt
    18541 ttgattgttt ttggtttggc tcgaacagca gtgtttaaaa aacatagaaa aacagtttct
    18601 agtatcttgc ttggcagctc gatgctgatc gcatttgctg gaatcatgtg gatgaatcat
    18661 caaacgggga ctattgaaaa tgagttaaca gatcggcatc cgatttcgat attattgcca
    18721 ttctatgatg ctgccagtca gccactttct caacaaggtt tattgggttg gggaatacta
    18781 gctatcacgg ctctgggatt tttccttgct gtaaaacagc tgatagtacc aaagcttaca
    18841 gagcaactga ctgattcaaa cagtgagttc aaaataaaaa gaacccataa aaagaaccaa
    18901 aatgtgcatc agcttttatt tagttacaat gctcaattag taaaagaacc taatttgatt
    18961 atgcaagttc tttcttcttc cttgttaact ccaatcattt ttattcttgc ttttgcccta
    19021 ggaggcgaaa taaaattaac tgatttagat aataagttaa tcggtgttgt tttcctggta
    19081 gggatcgcat tggctttctt aacagttaat cagacttctt ttatcagcaa tcttatttct
    19141 ttggatcaag aaaattttct gtttatccgt tctttgccaa tctctatgaa ccaatattta
    19201 aaagaaaagt tcagattcgg atggatattg cagagttttt taactggtgg gatcgcatta
    19261 ttaagcggac tgtcttttca gctgcctttg ttttttatcc ctagcttgct atttggttct
    19321 ttattcggct gctacttatt gtcactacgt tatttcgcta gagattatcg gttgctgctg
    19381 ctgaactgga ccaatattaa ccaattattt aacagaggtt caggaagttt gggtttagtc
    19441 gcaactatga tgggttcatt gatcatcagt attattctta tcgtcttata cggaatgttg
    19501 gctttgtttt atccattttg gttagtgaat attcctgtga tcggtttagt tctaatactt
    19561 tccgctctat ggatcgttta ttatcaacga acgttttgga aaaaatttga ataaagaaga
    19621 ggggccgtga caaaaatcat gtcgcagccc cttttttaca gatagagggt gttcaaaagt
    19681 cagtttctca gtattaagtc aattttatgt aaaaatgtga gaagctattt ttacaaaact
    19741 ttttttaata ctcataatta cttcttattg ctcctgcggt tacttgtcgc aatgtttgtg
    19801 agatattttg tcatcgctca aggctgaacg tctctttcac aaccttttct ttgttacact
    19861 tcgtttattt aaaaagccgt ttttttcgtt tcatcatgat tgcgtcacgc tttactttga
    19921 aattacggat gttatggtta aagacttctg ataatacaag acctaaagcg attgctccag
    19981 caatcataat tgcttggacc gcataatgag ccgcttctcg ataggattca gtaacgagat
    20041 ttcgaaccgc ttgataagct aaaccaccag ggactagagg aaccatcccg ggaatattga
    20101 aaatcgttac gggcattttc aaacgtttag agaaaagatc gctgatgaat gctactccta
    20161 aagaaccaag caatgaacca aaagcagcag atccgcctat ttgaacacag atccagtaga
    20221 tcatccagcc aaaagcacca gaaagaccac aacaaatcaa tgaacgccta ggtacatttg
    20281 taataacggc aaatgccgca gtcgctaaaa aactaaaaga aaactgaata aatatcgtcc
    20341 ccatacttgt gttcctttcc taataaaaaa gctggaaaat aaaagcaatc gcaaaaccga
    20401 tcatcgtagc agtcatcatc gcttctgttc cgcgagaaac tcctgagaca taatgtccag
    20461 ctagcaaatc acggatagcg ttcgtaattt gaactccagg aactaaaggc atcacacatc
    20521 cgataatgat tagatcctga ttgcttccta agccaaaacg tacgctgtag atagcggcta
    20581 tgccaatcaa taaagaagat aaaaattccg ataaaaattt gattctaaaa aatttcaaac
    20641 tatatagata agctgcgtat cccaatcctc caatgactaa agtcacaggt aaatcggtca
    20701 tctttccgcc aaataacacc ataattgttc cactgatcac tgccgcgcta acgatttgca
    20761 accagacagg aaagaaagaa cggtctcggt cgattgcttg cagttcgcag taaagttctt
    20821 ctaatgttag ctctgaagca acatatttac gtgaaagatc atttactttt actacttttt
    20881 ctaaattaat cgaacggttg gtaatttgtt ccattcggat ggtcgaggta cgatcaagac
    20941 caataaagag accggtttga gtgacatagc tgaccaaacg gaaatttcca gaagctaaag
    21001 caattcgact catcgtatct tctacccgat acatctccgc attgctttcc atcatgattt
    21061 tcccagcgag taaacaagtg tccagcaaca gatctaattc ttttcccgtc atagcatctt
    21121 ctccaataat tgattgatta gttttatttt actacaaaac ataccagaag cgtaaagaat
    21181 aaaaaaactt gaggaaggaa taaaagaggc gtatactgtt tttgtattgc gggtgtagtt
    21241 tagtggtaaa atcccagctt cccaagctga tgtcgcgggt tcgattcccg tcacccgctt
    21301 aaaataggtt gtgaaaaagc tgctctgcaa caagtaataa gaacagccaa gcaaaaacaa
    21361 cttcttatgt ttttaacttg gatggactta ttaccgcaga tgcaagcttt tgcgcaccgt
    21421 ttaccaagcg gttgtgaaat cagtgtattg tcttgagtat gaagaaaatt tttgaataat
    21481 aataaatacc ttacagatag agtggtgact gattagagac gaggaatccg tctctttttt
    21541 gtatttttaa gccatcttaa aacaggtttt attttttgct gtttctattt ctttctagta
    21601 tttatttata ggggaacata tgttaagatt tagggagctg ttagtaaagg agtaaagaaa
    21661 tgagcaaaaa aacaaccaag gcgatcgtgg ggatcgtcgc tgctgtgatt gcaggggcat
    21721 tcggtgtttc caccacacaa aaagattcag atatctttca gcagattaca actatttttg
    21781 attccacacc acaagcttct caagtagcgg atgtgccaga atatgatgga aaacatcaag
    21841 aaatagaaat caatgggaat cagccggaat ttacaaaaga ggatcttagc ctttccaaag
    21901 gaacatggga aagctattca aatattgata aattgaacag agtaggacaa gccaatgcta
    21961 tgcttggaaa agatttgttc cctactgaaa agagagagcc tttgtatatt gacccgacag
    22021 gttggaaaca aaagaaatta agtgacgggc aatggttata taatcgcagc catttaattg
    22081 gtttccagct gactggtcaa aataacaaca ttaaaaactt gatgacaggg acacgttcgt
    22141 tgaatgctcc atacatgctt gctcacgaaa atgatattgc ggcatatatc aaagaaacaa
    22201 atcatcatgt acgctaccgt gtcactcctc attttgaggg gaatgaactg gtagccaggg
    22261 gagtgcaatt ggaagcagaa agcattgaag acaaaaaaat tgaattcaat gtctttatct
    22321 acaatgttca agatggctac acgatcaatt atgagacagg acaagcaaca aaaacaaaaa
    22381 attagtagca gctattcgaa ttttttatga atattatgaa aaaattgtgt aaaaacatac
    22441 attcaaagaa atatagcgta tactttatga aaagagtact tttgataaag ctacagaaaa
    22501 aaggaaaaaa acatacaaat agtgtttctt aatttattcg gaagtttgga atatttgttt
    22561 gtagttttcc ctttcttcga gtaaaataag gttgtagaag gtaagctgga attaccttgc
    22621 gggaaagagg tgtagaatca tgggttttac agatgaaacc gtacgttttg gttttgacga
    22681 tagtcgcaaa aaagaagtga gcgaaacatt agcgattgtt tatcgggctt tggaagaaaa
    22741 aggctacaat ccaatcaatc agattgtcgg ctacttgctt tctggagacc cgtcctacat
    22801 tcctcgttat cgtgatgctc gaaatttgat tcgccgtcac gaacgcgatg agatcatgga
    22861 agtaattgtc aaggactacc tctcaaatca tggagtgaat ttatgagagt aatgggcttg
    22921 gatgtcggtt ctaagacagt aggtgttgct atcagtgacc cctttggctg gacagctcaa
    22981 ggagtagaga tcattcggat caatgaagca gaagaagagt ttggctttga tcggttgaag
    23041 gaattagtag cacaatatga agtagaccgg tttgtagttg gattacctaa aaatatgaac
    23101 aattccatcg gaccaagggc agaagcttcc atgtcatacg gagaaaagat caaagaacta
    23161 ttctccttgc cagttgatta tcaagatgaa cgattaacca ctgttcaggc agaacgtatg
    23221 ctagtagagc aggcaaatac ttcaagagcc aaacgaaaaa aagtcatcga taaattagca
    23281 gctgtgatga tcttacaaaa ttatttagac ggctcaggta agcaattatt ttaataataa
    23341 aagaaaagag gtaatcttat gacagaacat aaccattccc acgaccatga aggacacgaa
    23401 cacatcacat tggtggatga ccaaggaaat gaaacattat atgaaatcct actaacagtt
    23461 gacggacaag aagaatttgg acgtaactat gttcttttat atcctgctgg tgtttcagaa
    23521 gatgaagatg tagaattaca agcttatgca tacatcgaaa acgaagatgg aacagaaggc
    23581 gagttagaac aaatcgaaac agacgcagaa tgggacatga ttgaagaagt attcaataca
    23641 ttcatggcgg aagaagaaga atagactata aagctaggag aaaccttgat atgatagggt
    23701 ttctcctttt tttatttttt actgtatgcc atattgtatg ccatctagtc aatatttaag
    23761 tgttgtacta atttttcaac agtcttttct ttcgtttctt ttgccaagtg accgtaacaa
    23821 tcgatcgtct gactaatttt tgtatgccgt aatctagttt gaacttctac catagtagct
    23881 ccagcgtcca agagcattga agcatgagtg tgtcttgcta catgcacacc gagaaatgga
    23941 accatagctt tttcacaaat agtaatcaat cttgcataaa tagcgtggtg tgtgattagt
    24001 tctttataga taccacaaaa aatcatagtc ggatcagtta caccaagtgt cagcatatat
    24061 ttccgctgat taatctgcca tttttttaat atagaaattg ttctttcatc tagtggaaga
    24121 accccagcac tacaatcagt tttaggatca ctgattttat agccattttt ggattggctt
    24181 agtgttttat tgatggtgac cgtattttct tgaaaatcaa tgtctgacca attcaatgca
    24241 agggcttcac tgatcctaac cccgctataa aagagaaagc gtagtaacgt tttatcaaag
    24301 tcgtttcgat aagtttcagg tttgctgttt aggtaatcaa acaaggtgat cagttgttct
    24361 ttactgtaaa ctttgacctt ttctttatgc ttagtggtgg ttcttttagg cattaatacg
    24421 ttgtctagtg gattagtctc aataatccca agattgatag cgtagctaaa aatacgctta
    24481 gaagttgaat gaagtacctt gtattggtca gtagtttcag cccagctatt tacaatttgt
    24541 tgggcttttt ttaccgtgac ttcattcaca cgaagatttc catattttgg aagaatccac
    24601 tttctaaact tgatttcagt tttcatgaag gtggcttctc ggacagtggt tttatatgtt
    24661 tctagccaca agtcataaac ttctttaaac gtttcgttgt tcgctttttt aataccgttt
    24721 ttatcgtagt ccacttgcaa gcgtgacaag gcaagctggg cttctttttt tgttttgtaa
    24781 cctcgtctac gaaccttatc aggtttgcca gtcattttgt tcattccaag ataggcttca
    24841 tagagccaaa atttaccttt tttagtttca tattgcttga atgttgccat aatagttttc
    24901 cctccatagt gtagcaagcc gtgggggcgg ttggaggagg cagtttatta ttattttgaa
    24961 tagtgtttat ttagctcagt aacaagagct gtgaactctt ttagaagatc attttcataa
    25021 aattcttgat actctttttt ctcatctgta tttttttctg aatcattaat taatgagtca
    25081 tatcgtaaaa gcgtatttag aagagctgcg agataagcaa ttggggtact cccgtcagga
    25141 aattcaattc gagatcctgt tttaagatat tttattgcgt ttgttaaata aatcttctgt
    25201 gagacagtca ggttatcttc ttcgatgtta ttgatagcat tagaaagatt agaatcaatt
    25261 atagagttat ttttttcaat agtttttttc aattgctttt caagcacatt tcgcttaatt
    25321 tcgggcatca tatgcatatc tcttaatgta taagatccgt ttaatagata ggtagtggat
    25381 acatctaata cctttgaaag ttgtttaagc ctggtgttat tgggaagatt atagccattt
    25441 tcccaattac taacggcacc tttactggcc ggtggggata atttacctcc aagttgttcc
    25501 attgagagtc ccttttcaat tctagccagt ctaattcttt gtcctgtctc cactgcttcg
    25561 gggtattttt ttctagccac attttcacca ccattcatat attttctcta ctatatcacg
    25621 atttaaatat gtgtgaaaca taaaagttca aaaaagtatg ttaaaattct tgcaaatgaa
    25681 aaggtatgat ggtatattga gtttataaga ggtatagaaa tgtattcaag agcctcttgc
    25741 atttttttaa aatctttgta tagaaatgta tgctaacgag gggggataaa tatggaatta
    25801 aaaattgaca aactcacgct tgatgatcca gcttttaaaa ttattgacga tcgagttgtt
    25861 caacaagtag agcaaactca aggaacgtta ctttcattat tagaaaaaaa gtaccagttt
    25921 ccaaaatata tgaacaaggc acaagctgct aagtatatga acgtttcata caatactatg
    25981 atgcagaaat atgttcctaa cggtttaaag ttgattatag ttgatggagt cgtaagaatt
    26041 tcacaagatg aatgtgatcg ctttatggaa gaataccaaa aataaacgca agccgtgggg
    26101 gcaaagggat taataggagg aaataataat ggaatcgaca caaaataaag caatcgaaaa
    26161 agtattatca acaattctta cagaagacac agcggcagaa ttagcaaact tggaaggcaa
    26221 agcgctagaa gaaacgtttg aatgtttgta cgaacaaatg gactatcaaa aattgctacc
    26281 acaagaacca acggtaagcg gagtattgcg tggcttgaac gatttagtac aagcagagtt
    26341 taaagaacga ctttctattg aagagtatca agaaattttg tatcagcaag ttgagttgtt
    26401 agcgagcttg ctagggcttg aactggagga cgttgaatga aaactgaaat ttggaacgga
    26461 cacattataa gatttgtcga tattaatgat gaatggtggg cagtggcgaa agatgttgcg
    26521 gaagcgttag gtcttaaaca ggttactaga gccattcact ctttgcctaa agatggggtt
    26581 actactagta aggtcatcga ttcattgggc agaacacaag atgtaaacat catcaacgaa
    26641 aaaaaatatt taccgcatgg cattcaaaag ccgtaaaaaa gaagccgagg catttcaaga
    26701 ctggattttc gacatcatca aagaactacg ccagtccaca ggacttgaag gctttcaagt
    26761 attccgcatg ctagacaaag aacaccaaaa agaagcaatg actaaattaa gccacgctat
    26821 tactgaacca aaaccagtag actacattaa agcgaatgtg atagccaata aagctgtatc
    26881 aactatttat ggtcattcca aaatggtaaa aaagaaagat atgactcctg aaatgttggt
    26941 tgatcgtgaa cctattttag atgagacagt agaattaatg actgttaaag aaaaatatgg
    27001 gttgcagttt tcagtgagtg agaaaattta taatcgttct gctgaattgc agacaactta
    27061 ggagcattaa catgatcgag aacaaagaaa aagccttatc cataacagtc ttggcggaca
    27121 ggataaaggc aacttaattg ggataaaacc cgatattctt tgttccgatt ataccatatt
    27181 aaaaaatcgg agggaaccat tatgaaacga aacttaatta taggaagcat tttaatcggc
    27241 ggaattttcg gcttattacc attaattgca aaaatagcta tctttgcagg attagcgtta
    27301 tatctcttca ctgcttatga cgagtacgac tatcaattaa gaactggagg gcataagtag
    27361 atgtacaaaa caaaactatt aaaccaactc gatagccttg aattagagga aattaatcaa
    27421 gggatcgctg aactagaaaa taatatcggg aaaacctact ttggaaattc attcaatgaa
    27481 aaactaacag ttttgtatgt actcaaaaaa catgcagaac acaaaataat ttgtcgagaa
    27541 atcaacgagc taaaaaatca gattttaacc gcatggttaa acattactga tatgcaagaa
    27601 gcaagggtga aaacatttaa tacatgggta aagtatcaga atcaattaaa aggtgctgaa
    27661 tttgttcggg atgggttgaa atacgaactt gagcagttga agctcatgga ggtgtctgaa
    27721 tgatttatac cagtattttg aaaaaggagg agaggtttat tggcaaataa ttatcaagca
    27781 gcaacggaat tacaaaagtc gggatggtca atttatccct tatctcctgg aactaaaatt
    27841 ccaataaaag gctctagtgg ttggaatgat gcaactaacg attctaatca aattaatgaa
    27901 tggtggacgg aagatgcaac tagaaatatt gggttaatgc ttgaagatca tcaaatggtg
    27961 gtagttgacc tagatcaaca ttctgaaaca cgaaacggcg ttgagaatta taaaaaactt
    28021 gcttcaatgt atgatccatt tccttctact tatacggaaa tcacaccagg taaaggaatc
    28081 catttcttct ttaaaattcc tgatggtgta attatccaac aagaaacagg tgcatttgct
    28141 gatatcttcg ggcgtgatga taaaggtaaa agtttaagcg ggattgatat tatcactaaa
    28201 ggagttccaa tagcgccaac tatgattatt tcaagaagtg ttgggagagc atatgaacct
    28261 attgaaaacg tatctctaaa taatattgca ccagctcccg attggctagt gaacctactg
    28321 ctaaaaaaac cgcaagaaat aaagactcaa taccgacccg tagcaaaaac agggacagca
    28381 aaaaaattag atatgattgt tcaaggcgct ggcgaaggta gtagaaacga tcatttaact
    28441 aagttatgcg gttggttact atggcacggt gtagataatc aaactttagc agaattgatt
    28501 tatacagcaa atgcgtacaa tgaaccaccg ctaaaagata aagaagtgaa tcaaattatt
    28561 cgatcgatga ttaaaaaaga tttgaggggg aaagctcatg gctcataagc ataaattaga
    28621 tagtatttta gactttcccg aagccagcga gcgtgaagac aatatcattg aattgaaaac
    28681 ctggatgtca cgattaagat gcaataaaga cgatcagatt aaaagtaaca gtgttgtgaa
    28741 tgcagaattg attttaacca atgatagcaa tttagctgga acaattgctt ataacgaatt
    28801 tagcggatac attcacctat taaaagattc tccttggatc aatcgtaccg ctggagaatg
    28861 ggaagacagt tttgaggatg ccttaacggc atatattgaa gaaaactaca atgtagtttt
    28921 tgatgacaac aaaatacaca aagcagtagt aaatgtggct agaaagaatg ttttcaaccc
    28981 agtaaaagaa cgtatcgaaa aagttaaatg ggatcaacag cctagactgg aaacactgtt
    29041 tattgacctt ttaggggtag acgacaacct ttacacacga gaagtaacaa aacgttggat
    29101 agtcggatca gtcgcacgta tctataaacc aggaataaag tttgagatcg ttccagtttt
    29161 ggatggaccg caagggattg gtaagagtac cgttccagca ttactttaca cggatgattt
    29221 tttcaccgat tcattagatt cgctaggtga aaagaaagat gattatatgc agcttcaagg
    29281 caatgtaatt attgaacttg gagaattatc ttcaatgaac aaaactaaaa ttgaacagat
    29341 aaaaaacttc atcagtgcca agatcgataa aattagacct ccttatggtc ggaatgtcat
    29401 agcttgggca aggcaatgtg tatttattgg aacgtcgaat gatgggcagt atttgaaaga
    29461 tgatacagga aaccgccgtt tttatccttt gccttgtaag aataagccaa agatgaatcc
    29521 gtttaaaaca aaggatgaat attttcttca agtgttagct gaagcaaagg tgctttttga
    29581 taaaggacaa cgaatctatt ttagtcccga tgaagataaa gaagtcttag aaattgcaaa
    29641 agactatcaa gaggatgcca agatggagaa tccaattaaa gaagcaatca ctaaatattt
    29701 ggaaatggaa atcccgtata aatgggaaga agctccagcg tgggcgagac gttcttatta
    29761 tcagaactat cctgacagta aatgtaatga gaaaaattta cagcatttct ataatggagc
    29821 tactatgcaa caagagtttt atttagttga tagcgtactc accgctgata ttttggaagc
    29881 tgtttttgat aaacaagcaa aggatttatt gaatggtcga tcagatgcag aaactaaaaa
    29941 gattgccttg attattagca gtattcctgg ttgggaacgg aagcaactgc caaaaagaaa
    30001 taaacgacga ggattttaca ataagtcaaa tgcctatgaa aataaaaatc gagctggaaa
    30061 gtacaaaaag taacgggtag taacgggtca gtaacaccta gcccgttact agtttaccct
    30121 tactgcccca agggatacag caatttggta acggggtaac accttatttc cttaaaactt
    30181 ttgaaatagt tagctaatat gctggggaat aatgttactg gattttaccc gttacctgtt
    30241 accaaaacgc tagaaccctt gtccccgttg ggattgagtg gtaacgggta cctgttacgt
    30301 aggtgttacc acgtgttacg aatcaaggag gaaagtaaat gctcaatatt atttcaacaa
    30361 acaaagcacc gaactttcaa tatacagatg aaatggatcg gtttctaatg aacacgctgg
    30421 catttagtgt gggattggta acagaagatt attccacatt tgatccagaa gtattaaaga
    30481 taatggaaga agaacctgat tggctgcagg agtcagtagc gtggtgtcaa tcgctagtag
    30541 tgggatcatt ggtagatagt ggcaactatg atgatacagg tgagctaatg gatgaattta
    30601 attgtctgct taacctatat gatcgagcga gacaacgaga gcttacatcg aatgaggata
    30661 atttgttttt aaacatccat gataagttct tggctttgct actaacagat gatgaattga
    30721 taactaattt attggaggta gaataattat gcatatggaa agtattagat acttcgatgg
    30781 tgagaaacac attgagtatt caaacactca agaagatgta gactttatta gttttgagga
    30841 agataaaatc actaaagtta attttaaaga cggaacgtgc ttgaagatag tttcgcctta
    30901 tattgaatac aaatcaaaat gggaacaaga tgattctgac gaacgagatc gctttggttg
    30961 gtaatctatg gcagttaaaa aacaatgtaa tcatgctgga tgtaaaacat tgattgatta
    31021 taggcagaag tattgtggga agcataaagc aaagcaaacg gcaattaagc gtgaagaaag
    31081 aaagcaaagc gaaggtaaat attttcaatt ctatcaaagt agaacatggc gaaaggcttc
    31141 atacttgtat cggttaaatc atccagtatg tgaggattgc ctagaagaag gcttgataag
    31201 gaaagctgat gttgtagatc acaaaattga actaaaagat gattggaata gacggttaga
    31261 tgaaactaat tttcgttctt tatgccatgc acaccataat tccaagacag ccaatgaaag
    31321 acaaagacga gaaaagagta ccctttgagt taagggggca tagtgtgaaa cttactgaca
    31381 atcgatgcct actcattttg gtacaaataa ccgttgtgaa aaggcataag ggtaattaca
    31441 aataacgatt acacttgtaa tcacaagtga aaaagtatat aatgaaagta ggagatttat
    31501 tgaaaaatac aattgttatt actgataaaa cagggaaaca gcgcaccatt gagttacctc
    31561 attttggtca agtgaccatt caaatgcaga acggaaaaat catttatata gataaattag
    31621 ataaagaaaa attctgatcg aaaaacgaag gaatgtgagc ttaattgctt acgttccttt
    31681 ttcttttgtc tgaaaggagg acaacatggg acaccctaaa atattacacg atacaaaagg
    31741 caatatatca agtgaagaaa aagcaatccg tgtggacgct agagaagaat tgttcaagca
    31801 gcaaccatta ataaatatca cgccccctga ctggatggca gcgagcgcta gaagtgaatg
    31861 gaatcgtatc gtaccaacat taaaaaaaga ttatccattg agtgaagcag attatggttc
    31921 attggtagcc tattgtttag cctttgctcg aatgaaaaca gccgaagccg agataagaaa
    31981 atcaggtacg tttatcacat gcgaaaacgg agtaaagaaa gccaatccag cggttcgggt
    32041 tcaatcacaa gctatgagtg atttgaaaaa acaagccacc tcactaggta tgaccttaga
    32101 atcacgatca aaactagctt tgaacaaggt taaaaatgat gaacccgaag acccgttcaa
    32161 agagttgatg aattcatgaa tgattacatt gagaaagtcc tatcaggtaa gctgattgca
    32221 cccaagaaaa ttatccaagc gtgtgagcgt catataagcg atttggagcg ttctaagtca
    32281 gatagcttcc cttatgtgtt cgatgaagaa caagccacca aagcgattaa attcattgag
    32341 ttgctaccat ctacggacgg taaagcaatc aagatgttag gatttcaaaa attcattcta
    32401 ggcagtcttt atggctggcg tactaaagaa gggaattaca ggcgattcaa tcgagcgttt
    32461 accagtatga gccgtaagaa tgggaaaacg tatatcgcaa gtggcatggc tgccaatgcg
    32521 ttgattatgg aacaagaacc agcagaagca aggcaagtat tgtttgtaag taacgctttg
    32581 aaacaagcta aattgggcta tgatatgctg tctaattcac ttagaaacgt ggtcaagtct
    32641 agtaagtttt taagaccaca actgaaaatt atgaactcta agattcagca cttgccctct
    32701 aattcgttcg ctatggcact ggctagtgaa accagcacgc tagatgggtt tgcaccaaca
    32761 accgcaattc ttgacgagtg gcacgaagca aaaactcgta aaacgtacaa cgtcattaag
    32821 tcaggaatga cccaacaaaa gaacggctta ttgtgtgtta ttagtaccgc tgggcttgat
    32881 ttaaacgttc ctatgtacga ggaatactta ttgttagatc gtgtgctaaa aggcgaagaa
    32941 caagccgaca ggtactttat agcgatatgg gaattggacg atcccgaaga aattcacgat
    33001 caagagaaat ggatcaaagc caatccgatt tttgaaagtg aagaaatcaa aaaagtaatg
    33061 attccaacca ttcaagatga tgtgaacctt gctttgaaac aaaataacct taattctgta
    33121 ttggtgaaaa acttcaattt atggagacaa gcgagtgagg acagctatat gattgctgaa
    33181 gactggcagg caaccgaagt agaaccacaa gatattacag gcaagcccgt ttatatcgga
    33241 gtggatttat ctaaaacaga tgatttaact agcgtttcat ggatcgtacc gctagataac
    33301 ggcgaacttt attgtgattc acatagcttt gtagccacca aatatgggct tcaagacaaa
    33361 gaaaagcgcg acggtttgcc ttatcgagaa ctagaaaaag ctggtgagtg ttccattact
    33421 caattagaaa gtggaatcgt ggactatgac caagtatttc agtttattca agatttgatt
    33481 caagaaaatg atttggaatg tatggggatt tgttatgacc cgtataacgc taattcgctt
    33541 atcagtaaag ctgaaaaagc caactaccca atgttagaag taagacaagg aacgattact
    33601 ctaaacgttc cgacccgaac ttttagagaa caagtttatg aaggcaacgt tattcacaat
    33661 aaaaatacga ttctcaccca tgcagtgaac aacgctattt taaaaacgga taacaacggc
    33721 attcagatta ataaatcaaa gaacagtaac aaaattgatc caatagctgc attaatcaat
    33781 gcctatgtgt ttgcaatgga ttacttcacc acaacggaag gagcgaaagc agacaatgaa
    33841 ttttatacaa gtgaagaatt ttctttctaa ttacattcat accgttcttt tacttcttgg
    33901 attggtgtgt gtgttggttg ctatcacctt actaacaaat gtctactatg gcttgttagc
    33961 gctgggcata gtgcttattg gggtagcggt catgctaaat acagaacaga agggaggtta
    34021 aaagatggca ttttttaaag cgagacaaaa tacaacggga gatcctttcc tacaacatgt
    34081 ggtatcaatc caatcggatg attacaccac cagctttaca agcgttcgtg cattaagaaa
    34141 tagtgatgtg tttgcagccg ttcgaattat tgctagtgat attgcttcaa gtccgattca
    34201 attggtcaaa aacaatatgc cacaagctga taatgaactg gtgaagttac taaacgagaa
    34261 acctaattca gaaatggatg gttggcattt aaagtttgct ttggcggtca atatgttgct
    34321 aaacggtaat agctttgcag agattaaacg caacggtgaa aaggtagaag aaattcactt
    34381 attacctaac tcaagtgtaa cggttactca attagataat ggtacgttgt cttatcagat
    34441 tggtgataaa aaaagacgtg tgaagtctag cgatattttg cacttcaaat atttcaccca
    34501 agatggttta acaggattac caccacttta tgcgttacgt gatgaactga aaattcaaca
    34561 agctggcaac cgcacattgc acaatttctt tactcgtggt gtcagtgggt caggtatttt
    34621 gaaggttcat aagtcagatt tagacggatc agcaaagaac gcaattcgtg aaaagtttga
    34681 agaagccaac ggttcaagta gtggagataa tgctcttaga acgatcattc ttgatgaaac
    34741 aatggactac aaaacattag aaataaacac cgatgttttg aagcttatca attccaatga
    34801 ttggaacaca aaacaaattg ccaaggcgtt tggtgtaccg attgagcgtt taggcgttga
    34861 aaatgaacat tctagcaccg ttcaaagtaa tctccagtat atccaaagta cgctgattca
    34921 ttactttaat gtgtttgtga gtgaattaga tacgaaactt gaaaccaata tccgctttaa
    34981 ttccgatcag ttactagaga ctgatcctga aacaaaagta aaaaatgtat tggatcaggt
    35041 caaagggtca cttctcacga ttaatgaggg gcggtcgaaa atggggctac cccccatgga
    35101 tggtggcgat cgtttactag caagtttgaa ctttacgtat ttagatacgt tggagaaata
    35161 tcaattaaaa gaacaggaag gagttacacc agttgaataa tgaagaagaa aaggaaaaac
    35221 ggctgacaga agaagctgag ctaacagccg attctcccaa agtagagaaa gaaaatgaaa
    35281 aacaaccaac agacggcaaa actatttcag gctatgcgtt gaaattcggg caaccgtcaa
    35341 aagatttagg cggctttgta gaagtgatta cacccgaagc attaaaagag gtggatttat
    35401 caaatgtgtt cttattatat ggacacgatt attcaaagcc actagctagt gtcaaagcag
    35461 gtacgttgaa attgaatgtc gatgatacag gattacattt tgaagcagag ctaaccgaca
    35521 cgacctattc aaatgatgtg tatgagaata tctcaaaagg ggttgttgat tctatgtcct
    35581 ttgggttcgt gcttggatta gattcattcg acaaaaaaga agatggcaca attgaacgat
    35641 caatagataa aatcaaagca cttaatgaaa ttagtgtcgt gaccgttccc gcttatgatt
    35701 catcaaatgt ccaagtaaat aagcgttctt acgaatcgtt tatgagtaac aaccaagcaa
    35761 aacaaacaaa caatagctta gaatccactt ctaaagcaca aaaggagagt aataacatgg
    35821 aaaaaacttt aatcgataac gaaaaaacag aattgcgtgg gtatgaagaa tatatccgtt
    35881 cacaaggcga agtgcgtgat ggagtcacta ctgtaaatgc agcggcagtt gttcccgaag
    35941 aagtaatcgg tgaagtcttt gatttgaaac gttcaaatta taacttagct caatatgcaa
    36001 cagtaaaaac agtatcaaat ggacaaggta aatatccagt agcaactaac caacaagcag
    36061 tgttagcaac aaaagctgaa cttgctgaaa ttggtgatat tgacgctgaa atgtttactt
    36121 cagttgatta taaagtagaa actcgtgctg gtaagattgc cttatcaaat gaggttgtgg
    36181 aagattcagc agtgaatatt gtacaagagg tcaaagatca gttagcgaaa ttggtagaaa
    36241 acactgacaa taagcatatc atggatttat taaaaacatt cactaagaaa acggctgcta
    36301 cgttggacga tttgaaacaa ctatacaatg tggcattaga cccagcatta aataaaatgg
    36361 taattctaaa ccaaagcgga tattaccacc tagatacatt gaaagattca gatggacgtt
    36421 acattttaca acccgatgtg acagcaccta gtggtaaatc attattcggt atgccagtag
    36481 tattgattgc agatacattg tttgccaatc ctaaagctgg aacattccct atgattatgg
    36541 gggatattgc acaatctatc tttgttgctc gtagaaatca agtaacgact caatgggaaa
    36601 aattcgatta ctactcacaa ggacttgcag tgatcgttcg caacgattat aagaaaattg
    36661 atcaaaatgc ttcagtgtat attgagttta cgccagttgt aacaccaaaa gtatagaaaa
    36721 atattgggcg gcggtttatc ccactgcctt tttttcatta ggagagataa aatggtaatt
    36781 ttggatagca taaaaaaaag tatgcggatc gatcacacta ttgatgatga ctttattcaa
    36841 caattgattg atacagcagg cgaatatata aaaagtgcta ttgatagtag cgcaacggat
    36901 aaagatatgg ataattatca gcaatttgat ttggcggtgt cattacttac tcaacattgg
    36961 tatttgaacc gtcaagaagc cagcagcgaa cggataccag taacggtaca agcattagta
    37021 caacaaatga gaggtgctta ttatgccaat cattaagaat gtaaatgaat tgactgagag
    37081 agtcaagttt aaaaagacaa aacgggtaaa agatgaagat gggcagatgg tggatagtga
    37141 agaaactgta tttgaatgtt gggctaatgt gcgttcacaa atgctaaaag acgtgcttgc
    37201 tagtgtaggt accattcttg aaggaacgtt gacgtttatt attcgatacg atcaagatta
    37261 tgaactaaca aacgatatga aagtagcttg gaaaaacaag agttataaaa ttatttcaat
    37321 caatgaagga acggcgttta aagattatac aacgatcata gctaaacaga tttcttagaa
    37381 tgattacact tgtaaacgtt gtgggtattt agtataatta aggtagtaaa tgaagggtta
    37441 gctgcctgaa ttttgcaaga cttagctagt cgaaatctat tgttggactg aaaattgtag
    37501 gtgtggttgc aaacatgctg gactaagaaa gatgatagat gatgaacgtt caattttaat
    37561 acaggcatgc taggactgat tggatggttt tggcaagctg attgtgtaga aatcaaagaa
    37621 cacgtctgtt gtggacgtgt tttttttgtt ataattcaaa agaggtgatt taatggacaa
    37681 agcagagttt acaaattttt attggaagta ttatctacat ttagaaaatg agtttattaa
    37741 taccacagat tttgtgatgc tcgatgagaa taatttcaaa acattctcta ttgaatatca
    37801 aaaactacta ctagcgattg gttcggagtg tgagattatt ttcaaagaac tttgcggatt
    37861 tgatagcagt agcaataaaa gcataactga ttttaaagct gttattaaat ctagcgaatt
    37921 aatgtgtttg gataatggtg ttagggttat gaattcttta acattgactt cactaaaacc
    37981 ttttggagat gggtggcctg aagatacacc agattggtgg aaaatatata acagagtaaa
    38041 acatggtcgt tcttcaaatt ataaggaagc aaatttggaa aatgtgttgt atgctttagc
    38101 aagtctatat ttattagagg aatatttgca taagaaagta atactagaag gtgaagtaga
    38161 ctttataagt ccagagtcaa atctatttac gttatcttgg gaaagaaaac attcgtcgat
    38221 gcaaaaagtg acgtttgaaa aagtggattc aaattatgta gctccactca ttgattttaa
    38281 agaacaagaa gaaatttaaa aacccccacg gcttattgaa gtttttgtat gccatattgt
    38341 atgccatttg gtttaaatcg cttgaaaaat agtgatagat aactctaatt catttagtca
    38401 taaacgctgt tttgataacc tttatagttc tttgatatgg gtttctcatt catggcggaa
    38461 gaagaagaat agaacaaaag aatgaattaa taagatataa aaaaagggat tgtgacaaac
    38521 gtcttgtcac aatccctttt tccaaataaa cgatgttcaa tcagctgccc ctcggcatta
    38581 gctcgaaaaa cggcgaaata tgaagaacta ttttgccatt tgtttctcta ataatcaggt
    38641 caaaacgttg acttcacagt ctcttcctta aacggtgttc tcctgccaac tcctcggtca
    38701 caagtcacaa tattcaacaa acatgagaag ctgttttttg aaattgttcc ttgtgactcg
    38761 gagctgaacg gcaggctcac gacctctttc ttaaacggtg ttcaaaagct tgcatctgcg
    38821 gtaataagtt caaccaaacg aaaattatga ggagctattt ttgtttggct gttcttatta
    38881 cttgatgcag gacagctttt tcacaacctc ttttcgttta gcactaaatt tccttaaaaa
    38941 gtagaaaagc tttcgaagcc tcgtttgttt cttttactgt ataataaaag aaaagagtaa
    39001 caatcgctaa aagatataaa caagagaaag gaaatacaag atgattggtc tgatttattt
    39061 tgtggtgatc gttctggcga acacagttgg cgctatttcc gggatgggtg gaggcgtgtt
    39121 gatcaaaccg attcttgatc ttatcggcgc ccattctgtt gcagggattt ctttttactc
    39181 aacagttgcg gtattcacga tgtccattgt ttcgactgtg cgacaagtat caagcgggaa
    39241 atcactgaat tggcagattg tcggttgggt atctagtgga gctgttgttg gaggagtagt
    39301 cggcaacatt gtattcgaag tttttttaca gttatttgaa aacgagaagc atgtgcagct
    39361 gatccaaatt tttttgacgg tattgacctt ggtttttgcg ttcttctaca ccaagcatca
    39421 tcagccaaaa tttcatttga cgtcatggac ttggtacctt atatgtgggg gggttctggg
    39481 ctttttagct agttttttag gtattggtgg tggaccagtc aatgtttctt tgttgatgct
    39541 gatgtttgca ttgccaataa aagaagcaac actatattct ctatctacga ttttcttttc
    39601 tcaactggca aaattggtaa cgattgcttt aacaagtagc tttatgcgct ttgatttatc
    39661 tatgttgttt tatgttatcc ccgctgctgt tattggaggt ttgtggggag caagatttag
    39721 cagggttttg tctccaaaaa aagtgacctt tatttttcaa gtaattgtcc tcgtggttct
    39781 tttgatcaat ctttacaatg ctttcgtcat cttacaaaca ttaggagaat ctagactaac
    39841 gcaagtcaaa atcactgaaa catattgttc taaatgaaaa aaggagtata ctgtgataaa
    39901 aaaattcatt taaaaaaata aaaattggct ggtgatttgg atgttgcggg aaatgcgttt
    39961 aggagatgca gaagcactac gagaaatcaa tgcggaacaa ttaggatatg atgtaccatt
    40021 aaccgttacg gtgagacaaa tgaagaaact gttgaaggag ccagaaaaaa attttttctt
    40081 ggtctatgaa gatcctactt ctaaaaaagc agctggctat gtacaagcgg agtcctatga
    40141 atcgattttc agcgatccga tgttcaatat tatggcactt gctgtgtcta aacatgctga
    40201 aaaaagagga atcggaaagg ccttgatgac tggcgtagaa gaagcgaaaa gacgaggaat
    40261 atcagcaata agacttaatt ctgcagaata cagagtagaa gcacaccgat tttatgaacg
    40321 catcggttat cattccgata aaatgcaaaa aagatttttg aaaatcctgt aaatttttat
    40381 caaaaaatac ctggtcatca agccgatact tgatgatcag gtattttttt tgactaagaa
    40441 agtaattgca tcaagaaacc tgagatgatc aaaacgatgg caccaccaag ccgattgccc
    40501 atttgagcaa aagcaataag ttccatccga ttagctgcag ataagacagc tacatttcct
    40561 gtaccaccca tcgagttgtt gcataagcca gcagtaatag ttgattcgat tggatataaa
    40621 ccaaacaaac gaccgacaaa tcctgaaact actgaaatcg cgataacact tgtcaaacat
    40681 aagacaacaa attgccatgt caaagcagaa gccaatacat ttagattcaa taacgcaata
    40741 ccgataccgg caagaacagc tgctgtcaag tttttgacaa tcaagttgtt gaacatgata
    40801 gctgcatctt cgtaatattc tggtaatagg tttgcgattt tacagataac aacgataatg
    40861 atcatgaatg cgtaagcatg gactttagga acaaaatagt tacagatttg tcctaagatg
    40921 aagaaagtca atgataccat caaaccgaca cctaattgtg gaatggaagg ttttacattt
    40981 ctaggttttc catcgccaag gtcgcctttt tccattaatt taccattacc gttgaatttt
    41041 ggcattgatt gtcccgcacg agcaactaac gctgcaccaa tgatagctag gacatttgtc
    41101 attgctgtcg caggaatcag gcgggaaatg atagaagaag cgtccgtacc taaaacattt
    41161 gcataaatcg ttgataaagg tacagctccg gctccaacac caccagccat tgcgggcaat
    41221 gagatatata aaacggaatt tgcaaaacca tttccgataa gcatacctac gagtcctacg
    41281 gcaaaaaagg agacgaccat tgaaataagt gcaacgggaa taaaacgaac agaagctttc
    41341 atcaatagat tacggttcat accaaggatg ctaccagtaa tcaaggcagc aatataaaag
    41401 tctaaaaagc ccatattgct gacaaagttt tctgtggatt ttactacata ctcaggtaag
    41461 atcccaaatg tagcaatcgc ggcagaggca aagatcgcaa aaacggagcc accacctaaa
    41521 taacttttga cgatagggat ttttgttccg ataaaatgaa ataaattacc gaaaatgacc
    41581 aaaacagcga ttgggccaat catattcgtc ggtaattttc ctaaagccat tgcaatgatc
    41641 aggacaagga ccatgatcaa ataaaggggc aaacttacgc cggtaatttt tgttgaccaa
    41701 aacccttctt ttttcttttc ctcaactgca gttgcggttg ttgttttttg tgccattttt
    41761 acagatcctt tcttattctg tatcgtatga aaaaagccaa agagaagcgg caaaagagca
    41821 gtagttggct ggctgctgtt ttgccgcagt cgcttttttc tttttagacg tcatacaaag
    41881 tttctgtatg ttcttttact ataacaatct taatcttcta aagatttata ttcaggaacc
    41941 catttagcag attcaacagc ttctttgata tccgtgattt cttcacgatt caatttttgt
    42001 gcaacaactg attttgcgac agtttcagca atcgtttgag agaattcagt gatttttgct
    42061 actggaggca agatagctgc tcctggtttt gttacatcaa cgattccgcc taatgctcga
    42121 ctagcttgag aaatgatttc agcatttact cgtgtagctg ttgaagcaat caaaccaagc
    42181 cctaaacctg ggtacatcaa cgcattattt gcttgaccga tttggtaagt tacaccgtta
    42241 tattccacat cagcagcagg gatacctgtt ccaactaaag cttttccgtc cgtccattca
    42301 atcaaatctt ttgcttttgc ttctgccaat tttgttggat tagacaaagg catgatgatt
    42361 ggacgtgggg tatgagccgc catttctttc acgatttctt cagtgaatgc tccaggttgg
    42421 gtagaagtac cgatcatgat cgttggatgg attgctttta caactgcttc taagtttgtc
    42481 aattcatcag cattagtgaa ttctgagcgt ttacgagcga atgggatttg accaggagtc
    42541 aatccttttg tatcttcaaa caataaaccc tgtttatcta cttgatagaa atgttggcgt
    42601 gcttcttctt caggtacacc ttgacggatc atttcatcta aaaggatgtt tgcgatacct
    42661 acaccagcag taccagcacc aaatgtcaag atcgtttgat ctttcaattg ctcacctgat
    42721 atattcaatc cacctaatac accagctagt acaacgattc ctgtgccttg gatatcatca
    42781 ttgaaagtag tgattttatc ttcgtatttt tctaagatcg ttgcagcatt tcctcgtcca
    42841 aaatcttccc aatgtaataa caattctggg aataattcag tagctgattg aacgaattga
    42901 tcaatgaatt cgtagtaagt ttcgccttct acacgagcat gacgattccc taagtataat
    42961 ggattattca ataattcttc gttattagta ccagcgtcga ttgatacagg caagacttgt
    43021 gcaggattga taccagccgc agcagtgtag accatcaatt taccgatagc gatgtcaaca
    43081 ccgttcacac cccagtcacc catacctaag attccttctg catctgtcac aacgatcaaa
    43141 cgaatgtcgc gtccatctgc tgcgtttttc aaacttgctt tgatattttc tggttcgtcg
    43201 attgaaagaa atgcagcatc ttgtggtttc aagaaaattt cgttgtattg ttcgattgaa
    43261 tccgcaacga caggatcata aacgacaggc atgaattcaa ctaaatgttc gcccatcaat
    43321 ttataaaaca atgtccggtt cgtattgaat agattcatta agaagatacg tttttccaaa
    43381 tcggtctgtt tgcttaagta ttgaccgtaa gcttggacag attgttgttc caatgtttgg
    43441 acagtacttg gaagcatacc agtgattccg tattttgccc gttcttcttt tgtaaaagct
    43501 gttcctttat ttagaaaagg attatttaat aagtttagcc ctgtaagcat gaatgattcc
    43561 tcctaagttt taatacaaac gaagtatagg agtcagatga ggatatagtc aaaaagagca
    43621 ggtataataa attttattta tatgagtaat agagtcaaaa gaaatcaaaa tagcggtatt
    43681 tgttcttttt atatcaacaa tccttgcttg attactatgc gtatctctta tatgctaaag
    43741 aaagaaaagt agaagaataa aggatatgtt agatagataa atagaatctc tgaagaataa
    43801 atcacgtgat cgtgacgata aaatacactt acgtcaggtg ataaaaaata cataagtaga
    43861 aaactaagag gaggaacaga aaatgaaaga agttcaattg atcagaaaaa gcgaactatc
    43921 agaaggtggt tgcaatgcat gcggcgtagt agaagcaaca agctatacat taaagcttgg
    43981 tgccaacaaa gcgataatct ctgagttgac agtaggcggt cttgtggaca gtctggcgct
    44041 tgctgaaggt tttattggag aagatattta tgagatgttt tcagaaatcc gtcagttaaa
    44101 aaaaggggaa aactgcatag aggttcatca tgagagcccg aatgtgagat tcaaacgtgg
    44161 tgataatgag atgatcttca ataatcatgt gtccgatcac accgagctat atggaatcgt
    44221 gaatcaaata ctaactgagc tttttggatt gggaccttat gcgttcaagg aagaaaacgg
    44281 taatccaaaa ttaaacgaag aatggcaaga aacgattgaa atacaaagaa acaacccgca
    44341 cttatttcaa taggcatcca cagtatttcg taaaagggac tttgacacga cttttgtcaa
    44401 agtcccatcg ttttttatct atttgtgttc taaacatttc tttcagagta gtaacaactg
    44461 gaatgactga aatgtaaaca gattatttgc ctgtatcaat acggaagagt aatataaagt
    44521 gtgtaaacgc tatcatatta ttcattcaat tttttataga gggaaggcat tgaaatggaa
    44581 aaaacgtatc aagcaggtac aaatgaagga atagtggatt ttatcaatat ggaagattta
    44641 gaaatagccg cttcacaagt gattccagct ggtggttatg gttacatcag cagtggtgct
    44701 ggcgacttat ttacttatca agaaaatgaa cgggcattca atcatcagct gattattcct
    44761 catgtattaa aagatgtaga attacccgat acaactacac attttgacaa agaaacgctg
    44821 actgcaccaa tcatcatggc accagttgct gctcatggct tagctcatgt gaaggcggag
    44881 aaagcttctg caaaaggtgt agcagatttt gggacgatct atacagcaag ttcttacgct
    44941 tcttgtacat tagaagagat aagagaagca ggcggggaga aagcaccgca atggtttcaa
    45001 ttttatatga gcaaagatga tgggatcaat ttggatattc ttgaagtggc caagcgtaat
    45061 ggagcaaaag caatcgtatt gacagcggat gcaacagttg gcggaaaccg tgaaacagac
    45121 cgcagaaatg ggtttacctt cccactgcca atgccgatcg ttcaggctta tcaatcagga
    45181 gtaggccaaa cgatggatgc tgtgtacaaa tcttccaaac agaagcttag tccaaaagat
    45241 gtagaattta ttgctgctca ttctgatttg ccagtctatg tgaaaggtgt ccagtcagaa
    45301 gaagatgtct atcgttcatt agaatctggt gctggcggaa tctgggtatc taatcatggt
    45361 ggccgtcaac tagatggtgg tccagcagcg tttgattcgt tgcaatatgt ggcagaagca
    45421 gtagataaac gtgtaccaat cgtgtttgac agcggtgtac gacgcggaca gcatgttttc
    45481 aaagcaatcg catcaggtgc agatcttgtt gctattggca gacccgttat ttatggattg
    45541 tctttaggag gaagtacagg agtccatcaa gtgtttgatt tctttaaaac agaattggaa
    45601 atggtcatgc aattagctgg aacacaaaca gtagaagata tcaaaaaaat aaaattgcgt
    45661 gagaatcgtt ttatttaaga aacaaatgac gaaaaaaata ggagtgcggc agatgatgcc
    45721 gtactcctat ttttatagtt caaggatgtc actaatagaa taatttgaaa cgaaaaaata
    45781 aaattgaaat attttttcat acttaataaa aaaggaagaa tattcatgta aacgatttta
    45841 ttgttttttt ctcttttata caaaaagggt cataatttca agtaagcgga tgaattcatg
    45901 aggatttttt gcatactgtc tctactatac ttaggtcact aagaaaaagg agtgatttat
    45961 tatgaaaaag aacatgattg ggacattatt actttcaaca cttcttctag gcggcttggc
    46021 aacaccagct tttgctgagg gtcaagcgac ttcaaaagga gatattacct ttactgaacc
    46081 aacaaatacc gtggagcctc ttaaccctac tgatccttca aaaccagtag agccagcaga
    46141 tccggaaaat ccagcaactg gccagacagg tcctttaaca ctggatgtag ttcccgaatt
    46201 gccatttggt acacacgaga ttgaaagcgg aacaaaaacg tatcaagtag acgcttcaaa
    46261 aaacgataca ccttatctca aagtatcaga tcgtcgaggt gtaggtgcag atggccaagc
    46321 acaagggtgg aacgtgacag tttcggtttc agattttgta aacggttcac aagttttgca
    46381 aggcgctgaa ttagattttg gaacatccac tgttaaaagt acgtcagata acgaatccac
    46441 tggaccaact agtcaaactg taactgggtt gagtaaagca agtgcagcga caccaatatt
    46501 tacagcagca aaagatcaag gtctgggaac atggctttct gtttatgatc cagcaaatat
    46561 cacactgaaa gtgccgaaag cagcagctgg aacattcacg gctgatttga cttggaacct
    46621 cgtggctggc ccagtagcat agagtatgaa ataaattcaa caaactgcgg tgaaaatact
    46681 ataggtgaag gattttttac cgcagttttt gttgaaagga tgtggtggac aatgaatcaa
    46741 agtaaacgac tgtttgtttc gtttttttct attttaagtc tatttttcat ttttccgtca
    46801 atcagccaag caaaggattc agcaggagac tttggaatca aaccggtatt tccagagaac
    46861 caaatagata aagcaatcgg ttattttgat ttattagtgg caccggaaca aaatcagaca
    46921 ctagaagtaa ttatcagcaa ttcttcagat gaagaacgaa catttgaggt ctctgtcaat
    46981 ccggcggtaa cgagtgatgg tggaacgatc gattatagtc aaaaaaaccc aacgttagat
    47041 gagacattgc cgtttgatgt ccgtgacgtt ttgctcattg cgaaaaagga aatcaatgta
    47101 tcagcacatg cagaaacaac tgtacctata gaagtgaaaa tcccagcaaa aagctttaag
    47161 ggacgtgtat tagcgggtat tcatgtttca cctaaagaag aagctgaaac agaaaatgct
    47221 acagaaggag cacaaatcaa aaatcgtatt gcttataatc tcgcagtcgt tttacaagaa
    47281 agtcaagaga cgatagaacc ggatctgaaa cttttatcag gagatttgga cgaggtcaac
    47341 gcaaagccaa ctgttcagct tcgtttccaa aatcctcagc ctaggattat cagcaatttg
    47401 atatttacga gcaagatctt ttatgaaaat cagctttata ttgaaaatac gtctaatgca
    47461 tttttagttg caccaaattc gaattttcac ttgaatcttg atttagctgg tgataaagca
    47521 aaagccggcg attaccgcgc agaaatcata gcaaaatcag gcgacagtaa tgaatggcga
    47581 tttacacaaa actttacgat caaaaaagaa aaagcacaaa aagtaaatga aaattccgtt
    47641 tttgcagtac aagaacaatc tttcccatgg ctttatgcag gattggttgc tgcagttcta
    47701 gtgttatggt tgattttgct gtttttgtgg gtccacaaga aaaagaaaaa aggagaaaca
    47761 acatgatgag gtgatttcgt tgaaaacatc gatcttattg ggagggatta ttgcaagttt
    47821 gctgttcttc agctggcaag agccagtcca agcagatacc aaaagttcag gtacgattac
    47881 attttatgat ctaagtccaa ttccgcatcc aagtggttca gtcaatggcg catcaaaaca
    47941 gcagacacag ctaccgattt ataaagaatc taatcaacat ggcgtattcc cggagacgaa
    48001 tgaacaaaag atccgttttc tttatttgat cattggtata gaattatggc ttcttgcgtg
    48061 gttgttgtta tggagaagaa aggaaaagga ggatgaacat gttgctacaa aataaatttt
    48121 cattttttcg ctccttcttt tttacttcgc tttttgtttt aagtatattt atcttttcac
    48181 cttcggcaga agctgttgga gcaacgcctc ctgccatttc ttatgatcca tacacgtatg
    48241 aaaatatcgt acctccaaat ggtggacgta gtgcagtcaa tggcgggaag cttgtccaac
    48301 taactggggc taaccaattg cctaaattga ctgctactta tttgaacgat ggttcaaatg
    48361 atccttggaa aggtggcacg gtccgttttc attgggaaag ccatgtgaaa ctaacaaatg
    48421 tacttgattt ggtgaatatc actgcacaag gatttgcatt tgtggcgatc atcaatttgc
    48481 cggaacatgt atcaagcagt gatgtattaa aagcaattga ctggaacaac gcctacttgt
    48541 atattgccgg tgcccccatc aaggttacta gcggaagttt attatcagca ggaagccata
    48601 ccttgcgttt tgggatgggg tcgtgggata caaatactct attgacagat attattgcta
    48661 ttattacgcg aggcgaattc aacgtggacg atatcccgct tcaatttgat gttacagcta
    48721 atgtcgcgaa gatgacagaa aacggagata aatatgatac gagtccaaac aaaattttga
    48781 ccaagggtaa attacaacct tctatgtcta aaaaggccgt tttttctgtt gatttttatg
    48841 attcgaataa tattatccaa gatcgtatgt tcaattcgat tttagctcca gctgcaggta
    48901 gattttatcc taaattaact ggcggaaact tgaatccagg agcatatgca ttttctgcaa
    48961 gtgcagagat aaatacgtgg aatagttaca tctcaccaag tgattcaaca ggaaaatata
    49021 atacatttgc tgataccaca gaatacgtgg atggaaataa ccagaacctt ccaggctcta
    49081 ccaatagtcg gacattgacg atggggctga ctgaaggacg ttttgatcag ttgccattta
    49141 gtcgctttga tcgcgtagtc aactatttta caggaaaaaa cgttacacaa ggagcaatac
    49201 tgactcatac tccagcaagc acaagtggat tgaatcagac agccaatatc gtgtacagtg
    49261 ggaaagatgc gcaaggcgga ttgctttctc ctgttgcttt aaaggtattg gagcagtaca
    49321 agctagacgg aacggtttta ccaacaaact taacagccga tagtcagtgg ggaaagctcc
    49381 tttcttctgc atcgtaccaa gtcacggcca attggtcagc aactgaacta aaaaagggtt
    49441 cgatccatta caggctttat tcgaaaggaa cccaaaaatt agcgacagga tggacagatc
    49501 aacttttcca aacgatccaa tcaaataacg ggggtgtaaa tacagctact tctacactac
    49561 ctgcattggc ttcagggcaa tattattttg attatcgctt ggtggacgat gtacttacta
    49621 acatgtatcc gtcttttgcg tacaaatggc agtctgaaca agctggaatc accactcttc
    49681 ctcaaataac agtggctaat tttccatctg tgagtgcaga tagtcagcta aaaaacctta
    49741 gcagacaacc tgagacagga gatcccctgt ctgctctatc aggagatacg attcaagaaa
    49801 atgtgacatt cacgttaaca aaatctgggg atgcgataac cgacaaaaaa atcacgatct
    49861 cacttcctga aaatactact tatatcaatg gttccttaaa attaaatggt acaactatcg
    49921 cagataccgg cattcaacaa ggagtttctg tcccagcaga tctattgagc aaaataggag
    49981 ataccattca tcttacttac aactatcaat taaatactgt agatacttct ttacaatccg
    50041 tcagcatact gacaaaggca gctgtacttt ccagcaatat tacattagca gatggtgcta
    50101 agcttcctaa cccagttgtc caaacatctg ctaaaacaat tcttgtcccc aaacaagaat
    50161 taacattagt taatgtacca gatgatttta catttggtaa cgatctcccc aaaccgttga
    50221 agacaagtta ttatgaatca aaaggcgatt tttcttttga tgtgcgggat actcggcttc
    50281 caagcacgtc tccttggcaa ctgacaggta cattgacttc tttatttaag aatgatcaag
    50341 gtcaagaatt aagcggaaca aaattatact tcaatcattc tggatcaaag caattgattc
    50401 agcaaggtca aaacacgttg atttatgaga gtgatggaac agctaaagga gaggttctcg
    50461 ttgactttcc cgataccgat ggtttactct tagaggtaaa tagcagtacg aatgctcaac
    50521 ctggcgcaac gtatcaaggc atggtcacat ggaaactgac agctgggcca accagctaag
    50581 tgattagaat ttgtatggat ctgtgataac tgtcacagat cctctttttc aaggatgaga
    50641 aggaaacttc tgctgttaaa atcagaaatg cttgaaggag tggacttgga acttttcagt
    50701 ttgcttgaaa aaaatgaaca acggcaaatc aaacttttcc aacttttatt agaggaaaaa
    50761 ggagaggttt ccgttaataa cgtacttacc cgcttatcag ttgatcgggc taccttgaaa
    50821 gaagatctgt tttatttaca agctaacttg gaaaatatca aacaattgga aattgttatc
    50881 caagaaggga atattttatt aatcagacat ggaaatatag cagcagtcga tgtttattat
    50941 cattgttact tgcgctattc tacaaaatat cagatacttc tttatctgtt ggaaaatggc
    51001 tcatttgatc ggcagaaact tgtcatggaa cttaatatca gttcggctac tttgtctcgc
    51061 agagtgaagg aattaaatga ttctttaaat gagtttcatc tgaaaataaa aagcgggcgg
    51121 ctgaccggtc cagaaagtca aattcgttat ttttatttcc aattattttg gtttggacgt
    51181 ccctatcttg aaaacaaaaa agaatacagt gatttatcag gaaacacttt tttagatctg
    51241 ctgcaaaaag agtttagttt tgctattaca gaagaaggac gattgaaatt tgaaatatgg
    51301 ctttccatta tgaagaagcg aatgcgctgt acgaaaaaat ccaaaccaga ttatagcaat
    51361 cttcctgttg gattgtttca aacgacacaa tttttattgg acctccatac atttttgacc
    51421 cgttacttct ttcaatatgc ctttccttgg aatcaaaatg aaacgttggt tttttatctt
    51481 ttcatgatca gtaactttac attagataca cataactcgc atgtccagga gtttttgata
    51541 agcgaaaaat acaaagacga cgtagtagct caattgaatc gaacgtttaa acaatcgata
    51601 gaagaatatt tctcttttta tgtttttcca gaagagattt cgcaaaagat tgcgttgaca
    51661 gtgatgcaaa atcacgctca ttttgcctat tttagaggat ggatgaatat ttttggccaa
    51721 gaaggattaa aacagcggtt aactgaagta gaagataaac aattcctggt tttatgtgaa
    51781 agattggtca gacaaacatt tgctattgtt gattttactg aagtagacga ggaaaatgcc
    51841 cgctttgaat tatttgctcg ctatgcatct attttacgga cgctgatcaa gcagttagaa
    51901 ttacgtctgc aaattgctta tgatcttcct tatgaaaggc taatggcgga tatcgtgaaa
    51961 gaaatcatcc aggaacaatt gctgaatacg atcaaatatg atttagtcga atacgagaaa
    52021 gaaaagcagt atgatatcat tttgactagc caattgaaag agtacccgtc acagaagtcc
    52081 gctaaagttt ttgtattcac tagcaacgaa tataattatg atttccccta tttgaaccaa
    52141 tttttaaaag aatgttattt agaaaaattg aatttaagga tgaataaaac atgaaaatcg
    52201 tgatcattgg tgcttcccat gcaggcatca cagctgccct aaatctaaga aaacttcaac
    52261 cgaaagcaga agttttactg atcgatgaag atcataaaga tggactaggc tatgtttcaa
    52321 atggaatcaa cctttattta aaaggaaaga tacgtagttt agctgaagtt gcccataaca
    52381 tgcggactct tcaagaaagt ggggcaaaac tgatcaccga atggagagta actgaacttg
    52441 atccagacaa acatcagctc atcctcgcat ccaaagaagg aaaaaacgag accataacct
    52501 atgataaatt aatcgtagcg acaggttcct ctcctgtcac cttgtataaa caaattgaag
    52561 ctgaaaatgt ctacacctat aaaaatctag tgcaatctaa gcaagtactt gccgctttaa
    52621 aagaagcaaa agaagtagtg atcttcggtg ctggttacat tggattggaa ttagcagatg
    52681 ctttgagaaa taaaggatac attattcatc tagttgatta tatgccgaat gttttatcaa
    52741 gatatttcga taaggatatg atcaacagtt ttcaaaatca gctgcaaact aagcaaataa
    52801 atttttatcc aaatgaattc ttgatcgatt ggaaaaaatc agaagagaaa gtagtatccg
    52861 tacaacttct gtctcaaaca ataaaggcag atatggtcat tttttctgcc caaactcgtc
    52921 ctaatacgac attgttaaaa gaaaaagtgg ctttgtatga ggatgagact gtgatagtca
    52981 atgaatatct gcagacaagt gatccggaca tctatgcgat tggagatatc gtcccagtca
    53041 gttttgacaa aaataaacgg catctctttt tacctttagt tactcgagct gtacatatgg
    53101 caagagcagt agcgctaact ttgagtggtc agccaaccgc ttacgacctc agacaaaaga
    53161 taacagcagc agtcattata gactactttt taggaactgt agggctgaca gaagatgaag
    53221 cgccattctt ggaacaaaat accggttcgt gttcaggaga atttgatcta tttccacaat
    53281 acgacgaaga aaacaaaaca gtaaatgcaa agctgatcta ccatccggat acattagaaa
    53341 taattggcgg acagctgata agccaagaat tcttattatc agatttgaac ctgcttgcgg
    53401 atatcgtgaa acacaaaact acgattccac agctagcagt tgaggatttt ggatttctgt
    53461 ctgaatacac ctctcgtttt cactacctca atgagttagc ttttaaagta ctagctaaga
    53521 gagcaaatag caatagagta gataaaagac tgtgagaaat atcacggtct tttattgtgt
    53581 ggggatataa taaatattaa tcaatcgaga ataaaaaatt catataatga aatagcggaa
    53641 gaattttttg agcataatat tcgccaaaaa tttatcaagt gataaaattg ttgtataaaa
    53701 tgattatttc aggaggagga gttaaatgtt tttagcatta aatgaaatta tgcattcaaa
    53761 gttacgttat gcgttagttg caggggtgat gtttttgatc gcctacctgg tatttttttt
    53821 gactgggtta gcttatggct tagctcaaga taatcgaaca gcagtcgaca agtgggaggc
    53881 agattcgatt gtgctttcga aagatgcaaa ttcaaatcta gggatgtcca tgattactaa
    53941 gaagatagca gaagaagtcg aaggtgggaa agtggcgtat cttgcccaaa cacctggagt
    54001 cgtgactagt aaagacagta cagaagaagg aaaaatcaat gttagcttct tcggtatcga
    54061 taaaaatcaa ttcatcatgc ccaatcttgt tgaaggaaaa gcttttgata acgatgatga
    54121 ggcagtaggc gatattagtt tgaaagaaga atatggtcta gccataggag atacagttaa
    54181 gttatctggt agtgacaaga cgtttaaact aactggcttt acggatcatg ccaaattcaa
    54241 tgtctcacca gttctctata caaccatcaa tgcttaccaa gaaatccgct tcgaaaaaga
    54301 agatacaagt gaaaatgcac ggattaacgc aatagttgtc agaggtaaaa tcagtaattt
    54361 acctgaagat ttagaacaga tcaaaatttc taaattcatc aatgaattac ctggatataa
    54421 tgcgcaagta ttgacttttg gatttatgat cggatttttg atcgttattg cggctattgt
    54481 gatcgggatt ttcatttatg tactgacgat gcaaaagatt aatatctttg gtgtaatgaa
    54541 agcacaaggg atcacaggag gatttattgc gcgttctgta gtggcacaaa cattcatttt
    54601 atcatttgtt ggtattcttc ttggtctatt aggaacagtg ggaacatccc ttgttctacc
    54661 tgatgcggtt ccattccaaa gcaattggct gttttttggc gtcattagct tgttgatgtt
    54721 agtagtagct gtgttaggcg cactattttc tgttcggaca atcgtaaaaa tcgatccgtt
    54781 gaaggcaatt ggataagaag gaggaagaac atgaaagcaa tagaatttaa agaagtagaa
    54841 aaaagtttcc aagatggcga ccaagtagtt aaagcattga aagaaacaac catgagtatc
    54901 gataaagggg aatttgttgc aatcatcggt ccttctggtt caggtaaaag tacttttttg
    54961 actttggcag gcggattgca gacgcctagc agtggctctg tatttatcaa tgatcaagaa
    55021 ttcagtaatc aaaaagaaag cgaacgcgtt aaactacgtt ttaaagaaat tggctttatt
    55081 ttgcaagctt ccaatctggt tccttttctg acagtaaaaa agcagttatt attagtagat
    55141 aagattaaac atgaacatcg tcaaaaagaa gcaaacgaat tatttgagca gcttggcgtg
    55201 gataagttga tcaacaagta tccagaagaa ctatctggtg gagaacggca aagggtcgca
    55261 atcgctcgtg cattgtacaa tgatccgtcc attattctag cagatgaacc aactgctagt
    55321 ttggattcag aaaaggcacg agaagtagtc gatatcttgg caaaagaatc aaaagacaaa
    55381 aataaagcaa cgatcatggt tactcacgat acacggctga ttgacaaatg cgatagaata
    55441 tttatgatgg aagatggtgt attgaaagaa aaagaataac caaaaagcag gtggaaaaat
    55501 ggtccatcga tacaacaaag atacacagca aaaaattttg aaagaagcga ctgacttgtt
    55561 tatgtccaag ggatatctcg gcacttcaac aagagaaatc gcacaaaaag ttgggatcac
    55621 ccagcccaat ctctatcatt atttcggtga taaagaaaaa ctatatacgg cagttttaga
    55681 aaaccactta aaagatgttg gaaaagcttt gagagaaatc gttcaaacaa gcgaaacggg
    55741 atttcaagta accttgacaa aaatggcgca gtttttgatt gagacacatc tggtcgattt
    55801 gtttctgatg cttcacgatc ttgaaagcaa tctttcaaag gaaacaagag atcatctttt
    55861 ctttctatgg aagaaaaatt atcgtgaacc ttttgaagaa atcttttcag caaaccaatc
    55921 tgtgctaaga aatgggattt caaaagaaat cgcagcaagg cattttttct tagtgttagc
    55981 accttacatc actcggtcga aaagacctgt ggaagaaccg ctaaatgtgg cgcaattgat
    56041 cgatttatat ttgaatggtg tattaggaga agcgtaaagc tgttatatag ggagaaaata
    56101 gttaggtgaa gaagcaagat atgacgaaga tcgttatatc ttgcttcttt atataggtag
    56161 tttttcataa agacaaattt gttattctct catgattatc agggtatatt tttatttatt
    56221 atgtcggtgt tccaggaagt gttttaattt aataacgaag aaattaattg tttgtagaat
    56281 gaaggaaact atttattggg tagatgaatc accacgaata gtcaaaagga gatttcagga
    56341 tatgccaaaa atgaaaaaaa tcattttagc agtaatgtta ttttctacgg ttatatcttt
    56401 tacagcccct tttttgctta cttaagctga ttttaagttt tggcccttag tctggatcta
    56461 cgaggtgaga gtcaagaatg aaaaaaataa ttggagcttt tgtatttgca atcattatca
    56521 ttattatctg ttttcaaata gatgtttttg gtcaaaaaaa gatagttgga caaacggtca
    56581 gcagtacgaa cagtacggtt acaaagacaa aggaatcatt tgatgataca gaacaagaga
    56641 cattaatcaa aatcggaaaa aatgaccgta cactatatac agatgactcg ctaactaccc
    56701 cacttgcaac tataaacggc ggagagctgg cggagtttct ttctgaaaca aaaaatgctt
    56761 atcagatcaa gacaaatgat ggctatactg gatatttagc cctcgaagat ggaaccaaag
    56821 tcacaaagaa tatacaaaca aaaccggaag agctatctga tgcagtgatt gtattagatc
    56881 ctgggcatgg cggaaatgat actggggcat taagcaatga tgaacaaaca gaagaaaaag
    56941 atataacatt aagtacagcc ataaaagtaa aaaaggcgct agaggatgct ggagcaacgg
    57001 tttatttgac ccatactaca gatgaattag tacagcttgg agatatatgc gactacagtg
    57061 aagaaaaaaa ggcagatgtc tttatcagtt tacacgcaga ctctacggaa tatgcgaatg
    57121 aagcaactgg aatcacgaca tattattact atggacaaga ggaaacatta gcacagacaa
    57181 ttgctgactc cttcactgat ctgcctctgg attcaagagg aatctccact gggaactatc
    57241 aagttcttcg agaaaatctt caaccttcta ttttaatcga gatgggttat atgaataatg
    57301 atagtgattt aaaggaatta gtaacagaca gttatcagca gcagattgct gcaagtttga
    57361 cacaagcatt gaccacttat tttcagtaat aaataagccc agccaaacaa aaatagctcc
    57421 tcatattttt cgtttggccg ggcttattat cgcagatgca agcttttgaa caccgtttat
    57481 ttttttagta gcttcaaagc tttttctgta tttgcaaagt gaagtttggc atatttttca
    57541 agcataggca tgccgccttt ctccaatagt tttgccgcta cttggtcaga tttcgttcca
    57601 gctcctgatg gaagggtgat tccagcttca gctgatgctt tgtgtaactc ttccaaaaag
    57661 ctggcacgac tgatgataga agcagcagca acagctaaat gatattgttc tcctttagta
    57721 acgaagtaca gtttttcttg taattgattt ttttctaaac gcgcatattt tttaaaattt
    57781 gcttccggcg taaactgatc gatcaaaatc gcttctggtt tttctggctc gatttttttt
    57841 agcagcaaat ggatcgcttg attgtgcaaa gcgactttca tccgaacggc attgtatttt
    57901 ggttggatct cattgtattt ttctggagat aagacaagca gtttataggg gatggttttt
    57961 tttaagatgt cagcaagctg gatgatttgg ctatctttta actcttttga atctctaaca
    58021 ccaagtttac gtaattctgc aagctgatca cgtttcacat aagcagcaca tactgttagc
    58081 ggaccgaaat agctgccatt tccgacctca tcactaccta aaacggataa ttgactgata
    58141 ttttttggca aagaagaggc tgtttttgct ggcttggctt gtttatcctg tgcctccccc
    58201 catttatcag cttctattgc tgcattcgta ccttgaaaca tcacttttcc ggatgtataa
    58261 gcggtaatgg tcgtcccgtc tttttttgca gcaaagctag tataaggaat ctgtttattt
    58321 aacaaataag agcgatagta tgctttcatt tgactaagtt ggtcgtttgt tgctttgata
    58381 atgacgttgc tcataaaatt ctcctcgttt ttatacataa aactataccg caactcacga
    58441 cttttcgttt tctaagagat tgcgagacat agcatttttt taaagtttat catataatag
    58501 ttaagtatgt gaaaaatatt tgtggagaac ggtgaaagaa ccaacttcat ggtacactaa
    58561 ataaaacttt catcaaatag gaggaaatga ttcgtatggc gcacgaaaaa acacgctaca
    58621 aagcggtgat tgccaaccaa acatatacta ttatcggacg ggaaaccaag catcatatgg
    58681 atatcgtaac gaagctgatc aatgaacagt tagcagaatt gaaacaatta tcaccacaaa
    58741 tggataatga acaagcagca atcttgatgg ctgtcaatgc gctttcggat caattgaaga
    58801 aacaagaaag aatcttggag ctggaagaag aaacagcaga attaaagaaa aaaatgatca
    58861 aatttacaga gcttgaaaat cgtgtgaaac gcattgaagc aatcgagaac gaagctcggg
    58921 aagtattgaa agaaaatggt caagcagatc ataccattaa aaatcatgtg gaagcacaac
    58981 agattttaaa cgagaaacga aaaggacaaa ttaaacaaaa atcttctaat taagatcctt
    59041 ttatcaaaat aagaaaaatt taaaaaaagt tagaagagaa aggaacgtag catgctgagt
    59101 ttgctgattt tatttttatt gctaattgcg tttttttctg gagcacgtcg cgggtttgct
    59161 ttgcaaatca tattcgcgat tggatatgta ttgtcattta ttgctgccca gcatttttac
    59221 aaaccattag caagtcattt ggaattatac attccatacc cagctgtcac gccaacatca
    59281 aagttagcat tttttgatca ggtatttgcc tttcacctag atgaagcttt ttatgcagga
    59341 actgcttttc tgattatttt gctaattggc tggctgctta cccgatttgt gggggttttt
    59401 gtccatggat tgacgtatgt gccgatcttg agacaggtag actggattgc aggaggcatc
    59461 ctgtcactaa tcatggctta cgttactata tttttgattt tgcagttact tgcctttgtt
    59521 ccattagatg tggtccaaaa tcaattcggc gagcatagtt tcgctcgctt tatcgttgag
    59581 agaacgccat ttcttaccaa caagatgtat gagctttggg taacgaatat tttgaattaa
    59641 ggaaaatagt gctggaaaat atttcgtttt ttgtacagag tagattattt aagaaggctg
    59701 cgtagcgtat gtccggcaca gctctttttt catagtgaaa gataaggtga taaaatgaat
    59761 aaccgaatcc ttgaaacatt ggaatttgaa aaagtcaaac agatggtcag acaatttgta
    59821 gtgactgcac aaggaaaaga agaactggca gaattggtac cagtgagcga ggaacaaacg
    59881 atcacaaact ggcttcaaga aactgaggat ggattgaaag tgcaacgtct gcgaggcggg
    59941 atccctatac ctaaacttga aaatatccgt ccccatatga aacggattga gatcggagca
    60001 gacttgaatg gagtggagct tgcacaagtt tccagagtat tgtctacgac aagcgaattg
    60061 aatcgtttca ttgatgatct ttatgacagt gaaatcgaat ttgcacgttt gtatatgtgg
    60121 gcagatcagt tagtcacgat ccctgttttg agccgccgtt taaaggaagc aatcgatgaa
    60181 gacggacgcg tgactgatga cgcttctcct gagttaaaga gcataagaca gaacattcgg
    60241 cgaagtgaac aagctgttcg tgaacagtta gatgggatcg tccgtgggaa aaatgcaaag
    60301 tatttaagtg atgcgatcat caccatgcga aatgaccgct acgttatccc agtcaaacaa
    60361 gaataccgcg gtgtatttgg cggtgtagtc cacgatcaaa gtgcttcagg acagacttta
    60421 tttattgaac caaaacaagt ggtggatttg aataatcgtt tgcgtcaata ccaaatcgct
    60481 gaacgaaatg agattcaacg tattttaagt gaactttctg ctgaacttgt tccccatcgt
    60541 caagaaatca tccacaatgc ttatgtgatt ggtaaaatgg atctgatgaa tgcaaaagca
    60601 cgatttggta aagaagtaaa agctatcgtg ccgggaatca gtgaagacaa tcatgtcgtc
    60661 ttgaaacaag caagacatcc actgatcgat caggaaaaag tagtttctaa tgacatcaca
    60721 atcggaaaag actatcaagc catcgtcatt acaggaccta acacaggtgg gaaaacgatc
    60781 acgttgaaga ctttaggtct gttacaactg atggggcaag caggattacc gattcctgca
    60841 ggtgaagaaa gtcaaatcgg tatttttgag gaagtatttg cggatatagg agacgaacag
    60901 tcgattgagc aaagtctatc gaccttttct tctcatatga cgaacactgt agatatttta
    60961 tcaaaagtca atgaaaaaag tctggtatta tttgacgagc tcggtgcagg aacagatccg
    61021 caagaaggtg ctgctctagc aatcgcaatc ttagatgatc ttggtaaaaa gtctgcttat
    61081 gtgatggcaa caacgcatta tcctgaattg aaagtttatg gatataatcg ggcaaatacg
    61141 attaatgcca gcatggagtt tgatgtggat acattaagtc caacgtatcg tttgctgatt
    61201 ggcgttcctg gacgaagcaa tgcgtttgaa atctctagcc gattaggtct tgatacagaa
    61261 gttattgatg aagcgaagca gttgatgaat gatgagagcc aagatttaaa cgaaatgatc
    61321 acagatttag agaatcgccg gaaaatggca gagaccgaat atctggaaat gcgtcatttt
    61381 gtttctgagg cacaagaact tcacgatgat ttgaaagaag cttacagcta tttctttgaa
    61441 gaacgtgaaa aagaaatgga aaaagcaaag aaaaaagcaa atgaagtcgt gtcagaggcg
    61501 gaagaaaaag cagaaaaaat cattgctgat attcgtaaaa tgcaacagca gattgggcaa
    61561 ggaaatgtga aagagcatca gttgatcgat gcaaagaccc aattagcaaa tctacatcaa
    61621 gaagaaactt tgaagaaaaa taaagtattg aagaaggcga aagaacaaaa aacgttgaaa
    61681 ccgggagacg aagtgttggt tacgacttac ggccaaagag ggacgctttt acgtaaaaac
    61741 gggaatcagt ggcaagtaga aatcggtata ttaaaaatga atgtgtccga agacgagctg
    61801 acgcctgttg ctcctcaaaa agagccgaca caacgagtta tccatgctgt acgatctgaa
    61861 tctagtagtc acgtgccgaa tcaattggac cttcgaggaa aacgatacga agaagcgcta
    61921 agtgaggtag atcaatattt ggattctgcc attctagctg gttatcctca agtgactatt
    61981 gtccacggaa aaggaacagg cgcacttcgc aagggaatta ctgattatct taaaaaccat
    62041 cggagcgtca aaagctttga gtttgcaccg gcaaaccaag gcggaaatgg tgcgacaatt
    62101 gttaaattta agtaaagctt actaaaggta agcagatggt tcgctatcca agtatagaaa
    62161 tgctatacta gtcatagatt ttaaaaatgg aggtctttga tatgtcacaa gtaattacag
    62221 ataagacatt taatgaagaa acagataaag gacttgtatt gattgatttt tgggcaactt
    62281 ggtgtggtcc atgtcgtatg caagcaccga ttttggatca gttggaacaa gaatatgatg
    62341 aagaagaatt cagaattgct aaaatggatg tggatgaaaa tccagaaact cctcaacaat
    62401 tcggtatcat gagcattcca acattaatgt tgaaaaaaga tggtcaagta gtagaaaaag
    62461 ctgttggtgt tcattcaaaa gaacaactac gtcaaatgat cgatcaatat ttataaaaac
    62521 ttacagcaaa aataagctga gggtgggact gaatccagtt ccgtcctcgg tttttttgcg
    62581 gttgagttaa ggttattcaa attaatattt tttgagtata attacgttgt caggctggat
    62641 tgtttttttg acagacatgc tataataact ttaattgaat atgaagggga gtaccagatg
    62701 aacgaacgaa tcaaaaacaa attagcttta cttcctgatc agcccggctg ttacttgatg
    62761 aaagataaaa atggaacgat catttatgtc ggcaaagcca aaatattaaa aaatcgtgtc
    62821 cgctcatatt ttactggtag ccataatacg aaaacggaac ggcttgttag tgaaatcgaa
    62881 gactttgaat acatcgttac agaatcgaat atcgaagcat tgctcttaga gatcaatctg
    62941 ataaagaaaa atgatcctaa atacaacatt atgttaaagg atgataaaac ctatcctttc
    63001 cttaagataa cgaatgaaaa atatccccgt ttggtgatta ctcgtaaggt actaaaagac
    63061 aaagcactgt attttggacc atatcccgat gtcggtgcgg cgaatgagac aaagaagatc
    63121 ctcgatcgat tatttcctct gagaaaatgc aaacctagtc agacgaagga gccttgtctt
    63181 tactatcatt tgggacaatg tctgtgtcct tattatttcg acgtagatcc gaaagtctat
    63241 acgaaaatcg ttgatgaagt gaaaaacttt ttaaacggag gacacgaaaa aatcgagtca
    63301 gagatccatc agaaaatgga aaaagctgct gaaaacatgg agtttgaaaa agctgcagaa
    63361 taccgagacc agatccgtgc cattgagaca atcatgactc gccaaaaaat gacaaatact
    63421 gatttactgg atcgagatgt atttggttat gcgattgata aaggatggat gtgtgtccaa
    63481 gtgtttttcg taagacaagg aaagctaatt gaacgagatg tttcaatgtt tcctttctat
    63541 aacgaagcag aagaagattt cttgacttac ctcggtcagt tttatcagga aaatgagcat
    63601 ttcattccta aagaagtctt gattcctgat acgatcgaca agcccagtgt agaagctttg
    63661 ttagctacga aagtgctgca accaaaacga ggagaaaaga aaaaattagt tgaattggcg
    63721 agtaagaatg cctcagttgc tttgaatgaa cggtttgatc tgattgccag aaaacaggaa
    63781 cggacgatcg gagcagttga acgtttagga aacgcgatga atatcccgac cccaatacgt
    63841 atcgagtctt ttgataactc taatatcatg gggacgaatc ctgtggctgc gatggtcgta
    63901 ttcattgatg gaaaaccggc aagaaaagaa tatcggaaat ataaaataaa aacagtcaac
    63961 ggaccggatg attatgcatc aatgagagaa gtcatctatc gcagatattc gcgagtgatt
    64021 cgcgaagggt tgcctttacc tgatttgatc ttgatcgatg gaggaaaagg acaagtagat
    64081 gtggcaaaag atgtcttaga aaatcaatta ggaatcgata ttcctattgc tggcatggca
    64141 aaaaacgata aacataaaac aaatgagttg ctattcggta cagatttggc tgtagtaccg
    64201 cttgagcgaa attcaccaga gtttttctta ctccagcgaa tccaagatga agtccatcga
    64261 ttcgcaatca ctttccatcg gcagctacgc agtaaaaaca gttttgcttc ccgattagat
    64321 gaaattgaag ggttaggacc aaaacgaaaa aaaatgctgc ttaaagagtt caaatcgttg
    64381 aaaaatatca cagcagccac gacagaagaa ttacaagaaa tcggactgcc gaaaaatgtc
    64441 gcacaaaacg tatttgataa attacatcag gaatgaggaa agggcacttt acaaagaaag
    64501 taaagtgtcc tatcatttta tgtacaacaa aaagagcgtt tacgttttgt tggtaaataa
    64561 taaatcgctt acgtctggtg tctaaggata tatgtgattt cttgaagaag gagtgaagaa
    64621 atgttagaag tcaaggatct tgttaaaact tttgggaact acacagctgt cgatcatgtc
    64681 tctttccaaa tccccgatgg aaaaatcatg gggctaattg gccaaaacgg ggctgggaag
    64741 acaacgactt ttcgtttgat cttggatttt ttgacacaag accaaggaga agtgttatgg
    64801 aatggccatc atcttgggga gaaagattat gatgtcatcg gttatcttcc ggaggaacgg
    64861 ggactttatc cgaaagtaac gattcaagac caactgcttt attttgcaga acttagaggg
    64921 aaatcaagaa aagagattga accaaaaatc gacttttgga tggaaaaatt tcaggtaaaa
    64981 gggaaaaaga cggataaagt aaaatctttg tctaaaggaa atcagcaaaa agtccagctg
    65041 atcgccacgt taatccatga acctaaattg atcattttgg atgagccatt cagcgggtta
    65101 gatccggtaa atgctgaatt gctaaaagat ggaatattgg aattgaaaaa acatggttca
    65161 tgtgtcattt tttctagcca caatatggat aatgtagaaa aaatctgcga tcatttgatc
    65221 atgttgcgaa acggaaaaat ggttttgaat ggaaaagtac atgagattcg tgaatcattt
    65281 ggccgtacga agttattctt ggaatctggt ttaagccaac aggaagtaga agaaatcgaa
    65341 ggcgtgaaaa aagtgatcct tcatgaagac aatacgttag agattacctt agaagatcct
    65401 gaagctggga aagaaatctt tactcgtgcg actcagttcg gctacattcc tatgtttaac
    65461 cagcaaccgc caactttgga agagattttc aaattgaaag caggtgaaat cgatgcgtaa
    65521 gttttggatt attaccaaag atgtctattt aaaaaatgtt aagtcgattt ctttcttgat
    65581 catgatatta gtccctttta tcatgctggg tatcatttat gtagcaggaa actttgctca
    65641 acaaaatagt gatgtcaata aaatcggcgt attggctgat aatgagcaaa tcagtcagca
    65701 aatgagccaa gtcaaaacag atgattttga gttcaaagca gttgattctg aagaaaaagc
    65761 acaaaaagag ctttcggaag aaaaaatcga tgcgtattta gtagtctcaa ctgagaatga
    65821 taagataaat gggatgcttt atagcgaaaa ttcattagga caaagtacac aactactgat
    65881 acaacaacaa ctgactggct tgcaatcgat gcttcgagcg agtcaattag gcatttcacc
    65941 agaagaagta gctagcttga gccaacaagc aagtttgact cgacaaaaag tcaattttga
    66001 ttcaaaagga aaaatgacag tcggagaaga taactcgaca gtccaatacg tcgtaagtta
    66061 tgtagcaacg attgtcttgt tcattattat tttgacgtat gcgcagatca ttgcacaaga
    66121 gatcgcttct gaaaaaggca cgcggatcat ggaagtgatc ctgtccagta cgactgcaca
    66181 aaagcatttt tacggaaaat taacaggtgt tttacttgtt gcattaacgc aaatggcatt
    66241 atacggtatt atttttggta taggatacag tcaattcaaa gatatggaaa tggtcaaaaa
    66301 tatattagac ggtatctcat tggataactt gattggacca ttcttgtggt attctcttct
    66361 attcatgatc tttggcattt tgattttttc tgttttagca gctttatgtg gctctttggt
    66421 caacaaagca gaagatacag caaaagcaat tttgccagtg acttatctat ctctaggcgg
    66481 atacatgctt ggattgatac taggagcttc agatccaaac aatatcgtta ttcggatcac
    66541 ttcgtatatt ccattcttat cttcatatat tatgccggtt cgcttagcaa atgagacagt
    66601 cggtatgggt ggagcattga tttccttgtt ggtacttgta gccgtaacat tcttattgat
    66661 gatcttgtct gcaaacatgt acaaatcgaa tgtactcgtt tatagcgaag gcggattatg
    66721 gagttcattg aaacaatcga tttcaattat gaggaatgaa cgaaaaaaag cataaaacaa
    66781 tcctaaaata cagaaggaag ctggacatct attgttccca gcttcttttt gtatagacct
    66841 attttattta ttttactata ttggatatat attcattgaa aatagtgtat aacaacttta
    66901 taatattgag tataccaatt tttggaggcg ttttaatgga ccgttattta gatttacttt
    66961 cagaaaaatt cccctcaacg gaggatgtca tcacggaaat catcaatctc gaagcaattt
    67021 tgcagcttcc aaaaggaaca gagttatttt tgagtgatat acatggcgaa tttcctgctt
    67081 ttgatcatat tctgcgtatc ggttcaggaa atcttaaaga aaagatcaaa gacctttttt
    67141 ctgaacaaat gacggaaacg gatatcagcc aattcactat ttttacggct tatccagaat
    67201 atgcattaac gactgattgg tacaaagaac aagataaatc gcagctgatc catcatttga
    67261 tcgatctttt acggtttacg acagtcaaat atacccggtc aaaagttcga aaaggattgc
    67321 cgaaagaata tagctatatc attgaggaac tcttgtatat cgatgaccgt atcaatggaa
    67381 aaaaagacta tgtaaaaaaa atcattgaac aacttgtttt gatgaaggaa gaagaaaaat
    67441 ttttaacgaa acttgcacag acgatccaaa aatctgtcat cgatcatttg catatcgttg
    67501 gagatatttt tgaccgagga actcaagcag ccaaagtgat ggatcgaatc atggattttt
    67561 cttctgtaga tatccaatgg ggaaatcatg atattttgtg gattggtgcg tattgcggct
    67621 ctgaggcatg tttactgaca cttttacgga ttgcagcacg ctataattat ttatttgaat
    67681 tagagaaaga atatgggttg aatttacgtc cattgttttc ttttgctcat caaacttatc
    67741 agaagaatcc agtatttgcg cctaaaaaca gtaaaaatct atccgaaaga gagcaagaag
    67801 aattagaaaa aatccatcag gcactttcta tccttcaatt caaatcagaa catcagttat
    67861 tggatcgtcg acctgaattt aaaatggacg atcgtaaatt gctggaaaaa atcgactatg
    67921 aagcatcaac gattgattta gaaggtcagc tctatgagtt gaaaggaact tgttttcaaa
    67981 cgatccagcc agatgatcca aaaaaattct tggaagagga acaaaaagtg attgatagtt
    68041 tgatgtattc attccagcac tctttgagaa tgcaaaaaca tatgacgttt ttgatcgaaa
    68101 aagggggaat gtatctcacg aacaatcagc atgtgctgtt tcatggctgt atacctgtag
    68161 acgagaaggg acagctctta gcatttgaat tagaccaatc ttatcgcgga aaagaactgc
    68221 tgggcttttt tgaaaaacag ataactgaaa gcgcaaaaga tctgactgca aaagaagatt
    68281 tagcaaccga tttgatttgg tatgcgtgga gtgggccatt ttcgccttta ttcggcaaga
    68341 gtaaaatggc gacttttgaa cgttattttc tcacagagcc tcatacgcac gtcgagaaaa
    68401 gcaatcctta ttatcacttg cgagatgaag agtggttcag tgaaaaaatt ttagcagaat
    68461 tcgacacaaa agaagaaggg tcagcaatca ttaatgggca cacgccagta aaagtaaaaa
    68521 aaggggagtc accgatcaaa gcaaatggaa aagtatttgt cattgacgga ggtttatcca
    68581 aagcttatca aaaaacgaca ggaattgccg gttattcact attatgcaat tcttatggtt
    68641 tccaaatcgt gacacattat ccgtttttgc ctattgaaca acaatttgca aaaaaatccg
    68701 accaaacaaa tgtgaaaaaa gtaatcgaac agcaactacc acgcaaactc aatcgtgata
    68761 caacaaaagg tatggaactg cagcagcaga ttacccagct caaaaggctg ttggactatc
    68821 gaaaggacga ttgagaagaa ttccagtgaa cattgttcca tagactggag actgagacaa
    68881 aagtcgtgtc gcagtctctt tttccggata aacggtgttc ttctgccaac tcctcggtca
    68941 caagtcacac tattcaacaa acatgaaaag ctgttttttg aaattgctcc ttgtgactca
    69001 gagttgaacg gcaggctcac gacctcttgg tataaacggt gttcaaaagc cagtttctcg
    69061 gtattaagcc aaatttatgc aaaaatgtga aaagccattt tcacaaaatt tttcttaata
    69121 ctcgaaacta aacagctttt tcacaacccc ctcagaaagt ctattaaaat tcattcacaa
    69181 agaaatcgaa taagcgctgt tcagatggat gtacacggtg ggtaagttcc ggatgccatt
    69241 gaacaccgag gattttatgc atatcatctt tgctttgaac cgcttcaatg agtccatcgt
    69301 tagaaaaagc gatggctttt aataaaggtg aaagatcttt gactgcctga tgatggtaag
    69361 aattcacaaa atatggatcg gggagaaggt tgcttaacaa actgtctgaa acaatcttga
    69421 cttcgtgagt cgtaaattgc ggggcagtgg gctgttgttc atgttttact gaccactttg
    69481 gatataatga aagatcttga taaagtgtac cttccaaaac gacattcaat agttggagtc
    69541 cccggcagac tgcaaaaatt ggttttcttt gtttcaatgc ttccaagatc agtgcctgtt
    69601 caaattggtc tcgttgaata tttgtttccg ttagctttgg atgaggatct tccatgtaaa
    69661 gttgtggact gacatcttga ccacctgcaa gaataagttt gtcgatttgt ccaatcagtt
    69721 gaggagctga atctggagac atgactggca gaataagagg caatccttga gcatctaaaa
    69781 ctgcatccac gaatccttgc ggtgtatagc tcacttgatt tccttggaaa gtatctgttg
    69841 ctcgaatcag ttgatttccg gcaatgccga tgattggttt catttgtatt ccccctaaag
    69901 tagacttatt gtaacaagga tttaaaaaaa attaaactat gtaagacttg cccctatact
    69961 tatctgttct tgctgtgtta ctatctgtaa agagaaattt cgtgtgaaat tcatgacgat
    70021 agttgaaaat attgcttaat ttgttataat aaaaagtaag cagaaataaa aaggttgggc
    70081 gtaagcttca aggatctagt tcttcaaggg gtgagaagga cattttattg aaggggcctg
    70141 cctatactaa gttatcttta gaggtacata ctttcaatga aaaaagaaag catgtacctc
    70201 ttttttaaat cgaaaggaag tgaagcaagt gttagaagct ttggaacaaa tccgaaaagc
    70261 agaagaagaa aatgaaaagc gtgctcaaac actgcggcag cagctgaaga tctatgcaac
    70321 agaaaaagag caggaattgg aaacgatcca aacaaactat cgacaacaac taaaacagtt
    70381 ggtggaagaa aaagaacaat ttgaaataca agaattagaa aaagaaaaaa tgaaattgaa
    70441 agcagaagca gacaaggtgc aagcaacttt gaaagatcaa tatcaaaagc atcagagtca
    70501 agcgatcggt gcgatcattg aaagggtgaa agaaacttat ggccgtcact aagatggaaa
    70561 aagtgaccct catttcagat aaaagaaatc aggagaggat tttacaagca gtacaaggaa
    70621 tccaaaacgt tgaaatccgg gatctgtatc aaaatagaac aaacaaccag tgggtggaga
    70681 agtattttcc agataccacg attattgata aagaagcaaa attaagcgct ttaggtaatc
    70741 ggttgaaaga catccaagaa gctatccaat tcatacaaca ccacggcgat agccgtcaaa
    70801 agaaactcca tttgaaacgt caagaacttt ccttacaaga tttggaagcc aattattccg
    70861 aagaaaattt cataaataaa ttgaaagaag tccttgattt aaaagaaaag tgggaacaac
    70921 taactgaaga acgtgatcgt ttagaagaag aggaagaatg gcttcttcat tggcaacagc
    70981 tggatattgc tccaagtatg tatgcaagta agacgaccat ttttgagatg gggactgtga
    71041 gtgcagcaaa ttttgaaagt ttcaaggaag aactgagtaa gcttgatgac gtttatatgg
    71101 aagaaataga ttatacgcca aaacaagttt atctttcgta tgttgcttta aaaaaatcag
    71161 ttgctgttat agaagaaatt gctgggaaat acgggttcaa taaagaaacg tatccttatg
    71221 aacaaaatcc taaagaaaaa ctgcaagaga ccaagcagca attatccatt gttcacgagc
    71281 agcaaaagaa gataacgaca gcgttaggtc agtgcagtgg ctatatccaa gaatttgaat
    71341 gggtagaaga agtcacactt gccgttgcag aacgagaaaa aataaaagaa cggtttatcc
    71401 atgcgactta tctgatcgtt ttgcaaggtt gggtagatgc agaagaaaaa cagaatttgc
    71461 tgcatgtgtt aaacgaaacc gtatcagaag aagatatata cgtcagtttc gaaacaccaa
    71521 actcagaaga gattcagcag gaagtcccta ctaaattgaa aaaccatccg cttgtcgaac
    71581 cttttgaatt gctgactgaa atgtacagtc tgccaaaata tgaagaagta gatccaacac
    71641 cttggatgac accattttat cttgtcttct tcgggatgat ggtcgcagat gttggttatg
    71701 gtttgctgat gctcattggg acaatactag ctcaaaaact acttgttcta ccacgcggga
    71761 tgaaacgttt cgtaaaattc tttgagattc tctcgatacc atcgatcatc tggggattga
    71821 tctacagttc atttttcgga cagtcattac caaaagaact gtttggcatc cgcttgcctt
    71881 tcccaatcct atctacgacg gatgacgtca atacgatttt gattttatcc gtgattttcg
    71941 gtctgataca gattttggtt ggattatttg tggcagcaaa ggaaaatatc aggagaaaag
    72001 attacttgag tgctgtcagt gatggatttg cctggcaagg gatcctaatt gggatcgtta
    72061 ttgcgttggt tggtgccatg ttgataaaaa atacagcatt tgtttacctt ggcgctgggc
    72121 tatcgatcat tgctgcctta tgtatcttga tcgttccgat tatccaaacg ccgtctaaag
    72181 tcaaaggtgc tgccaaaggt gcgtataatc tttacggact gaccggctat atcggtgatt
    72241 tagtcagtta tacacgtttg atggcattgg gtatttcagg cggaagtatt ggagcggcat
    72301 tcaatatgct agttgctttc atgccgccag ctgctcgatt cagtgtaggg atccttttga
    72361 tcatcgcttt acacgcactg aatatgtttt tgacactgct aagtgcctat gtccatggcg
    72421 cacgattgca gtatgtcgaa ttttttggga agttttatac aggaggcgga cgtgcctttg
    72481 atccgctgaa aacggcggaa aaatacgtca acatcaatca caagaaaaaa aacaataaat
    72541 aattggagga tttttatata atgatggatt acttaattag tcaaaatggt ggaatggtat
    72601 ttgcggtatt agcgatggca acagcgacga ttttttcagg gatcggttca gctaaaggtg
    72661 ttggaatgac aggtgaggca gcagcagcat tgacaacaag tcaacccgaa aaattcgggc
    72721 aggctctgat tctgcaattg cttccaggta cgcaaggttt gtatggattc gttattgcct
    72781 ttttgatttt tatcaactta ggaaatgaca tgtcagttgt acaaggactg aactttctag
    72841 gtgcttctct gccgattgct tttacaggct tgttttcagg tattgcccaa ggaaaagtcg
    72901 cagcggcagg tattcaaatt ttagcgaaaa aacctgaaca tgctacaaaa ggaatcattt
    72961 ttgctgcgat ggttgaaaca tacgcgattt taggtttcgt tatttccttc ctattagtgt
    73021 tgaatgccta agcataaagg aggaaaagca gatgaacgcc attgaaaaaa tcatctctca
    73081 gatgaacgaa gcagcagagc aggaaagagc ggcgttagaa caagaagagc gaatgaagat
    73141 cgatcaaaac tttgaacaaa aacgtacgca agttgaaaca gaacatcaaa aacaaaaaga
    73201 aaaacaaatc gaattactcg aaaaaaaata ccgtcagcta aggaatcgcc agcaagtaga
    73261 agtacgacaa gaaaatttga atgcgaagca ggaattttta agacgattgt ttgcagatgc
    73321 ggtaactgaa atggaaaatt gggatgaatc tgaacaaatc cagtttatca aaaatgcatt
    73381 gtattcatta cctttgacag gaaaagtagc attcattgct ggagaaaaat cagcagccta
    73441 tctttctcag acgttgttgg atgaatggaa caatgaactt ccctttatga tggttttaag
    73501 tgatgaaact gttgctgatc aagcgggttt tctgataaac gatcaaggag ttcagtataa
    73561 ttttcttttc agcagccttg tacaagatat ccaaggaacg atgagttttg agattgccaa
    73621 tcaattattc gaataaggag ggatcagtgt atggaatacc acgaactaaa tcccttgatt
    73681 cgcggaagag agcttgaact tttgtccaat gagacatttg aacggatgat tcaaacaaat
    73741 tctgtcgaag cacttggtga aatattgaaa tccacgattt acagtccata tatttatgac
    73801 ggatatgaat atgacttcga acagaatctt ttaaaggagc agagccgtct atttcgctgg
    73861 ttaaaggaat cagcaccgga gcctgaaatc gtttggatct atacgatgcg ttatactttc
    73921 cataatctga aggttttgac aaaagctgag atgacaaatc aaaatctgga ccatttgtat
    73981 atcgacgatg gattttattc attagaaacc ttgaaggatg ccattcatac gcaagtttca
    74041 aatgaacttc ctgaaagcat tatggacagt atacgagaag tacgtgatta ttttgaagag
    74101 tctaccattc ttcagggaat tgacgtgatt tatgatcgac agtttttgac agagcagcga
    74161 cggcttgccg ataagctagg atatcaagaa ttgctgacag aagtcattgc ttttattgac
    74221 ttgaccaata tcacaacgat ggctcgagga atattgcaga aaagaacata tgggttcatg
    74281 acgacggtac tttccagctc gggaagtatc gaaaaagaag tatttttgaa ctttgtagat
    74341 aaagatatgg aagattacac gaattttcta ttagagacag attatgctga ttttctgcgc
    74401 cctgtcatcc gtgagggaaa tattgatctc gtaaagcttg aacagttgaa agatgattat
    74461 ctaagttcat tgtatcaaga agcacaaacc caggctttcg gaccactgcc actactagcc
    74521 tttttgaacg caaaagaggt agaaagcaaa aaccttcgtt tactggttat cggcaaaaga
    74581 agccatttcg aatcagaaac aatcagaaag cgggtgagac aagtctatga cgcataagat
    74641 cggtgtagtt ggcgacaaag attctgtttt gccattcaaa ttgtttggct ttgatgttcg
    74701 ttatggtaca accaagcaaa ccgttcgtca ggcaattgaa gaaatggcaa agaatgagta
    74761 tggcgtgatt tatgtcacag agcaatgtgc agcattgagc ccagaaacga tcgaacgtta
    74821 caaggaacaa atgatacctg ctatcgtatt gattcccaat catcaaggat cattagggat
    74881 agggctggaa gaaattcaaa aaaacgtaga aaaagcagta ggtcaaaata tcttatagta
    74941 tgaaaaggag atagaaattt tgcaaattgg aaaaatcata aaagtctccg gacctcttgt
    75001 aatggctgag aacatgtctg atgccagtat ccaagacatg tgtctagtgg gagatctagg
    75061 agttatcgga gaaattatcg agatgcgtgg cgatgtggcg tctattcaag tatatgaaga
    75121 gacttctgga attggtccag gcgaaccggt tcgctctact ggtgaagctt tatctgttga
    75181 attaggacca gggatcattt cacaaatgtt tgacggaatc caacggccat tagatacctt
    75241 tatggaaatc acacaaagta atttcttagg gcgcggagtt caattgcccg cattggacca
    75301 tgagaaaaaa tggtggttcg aaccaacagt agaagccgga gaaacggtga gtgctggaga
    75361 tgttatcggg atcgtagaag aaacaaaagt tataaaacat aaaatcatgg tgccaaatgg
    75421 gataaaagga acgatcaaaa caatcgaaaa aggttcattc actattgatg aaacagtatg
    75481 tgtcattgaa accgaaaatg gtgacaaaaa tttgacgatg cttcaaaaat ggccagtaag
    75541 acgtagtcgg ccaatcaaag aaaaattaaa cccggatgca cccatgatca ctggacagcg
    75601 agtgattgat acattcttcc cagtgacaaa aggaggagca gcagctgtac ctggtccttt
    75661 tggtgcaggg aaaacagtcg ttcagcatca aattgcaaaa tgggccgatg tggacatggt
    75721 tgtctatgtg ggatgtggcg agcgtggaaa tgagatgacg gatgttttaa atgaattccc
    75781 tgaattgatt gaccctaata caggagaatc gttgatggaa cgtacggtat tgattgctaa
    75841 tacatcaaac atgccagtag cagctcgaga agcttctatc tatacgggaa tcacaattgc
    75901 ggaatatttc cgtgacatgg gttatgacgt tgctatcatg gcagactcca cttcacgatg
    75961 ggcagaagca cttcgtgaga tgagcggacg tttggaagaa atgcctggtg atgaaggtta
    76021 tccagcttat cttggttcac ggcttgcgga atactatgaa cgatctggaa gagtcattgc
    76081 attaggatca gaaggtcgcg aaggaagtat aaccgcaatc agtgctgtat ccccgtctgg
    76141 aggggatatt tcggaaccag tcacacaaaa tacattgcgg gtcgtaaaag tattctgggg
    76201 tcttgattcc agtttagccc aaaaaagaca ttttccttcg atcgattgga tacaaagcta
    76261 ttctctttat tcaacagaag tagggaagta tatggatcat atccttcaag ctgactgggc
    76321 atccatggtc accgagggca tgcgtatttt gcaggaagaa cagcagctga atgaaatcgt
    76381 gcgtttggta gggattgatt ccctttcaga taatgaccgt ctgacattag aagtggcaaa
    76441 atccattcgt gaagattatt tgcagcaaaa tgcttttgat gatgtcgata cattcacttc
    76501 aagagagaaa caattcaaaa tgttgaagat gatcttgacc tttggtgaag aaggacgccg
    76561 tgcgttgtcg ttaggtgctt atttaagtga gatcatggac ggtaccgtat cgattcgtga
    76621 aaggatcgga cgaagcaaat atatcccgga aacagaatta gaaaaactag atcaaattat
    76681 tggtgaaatc aagcaaacga tgcaaacgat cgtttcagaa ggaggcatga gcaatgatta
    76741 aagaatatcg tacgatcggt gaagtcgtcg gtccattgat ggcggttgaa aaagttgctg
    76801 gtgtcaaata tgaagaatta atcgaagtcc gtatgcaaaa tggcgagatt cgtcgtggac
    76861 aagtattgga agtccaagaa gataaagcaa tggtccaaat attcgaagga acaagtggta
    76921 tcaatttacg tgactcttct gtacgatttt taggccatcc tttagaacta ggtgtatcgg
    76981 aagacatgat cggtcgagta ttcgatggtt tgggacgacc gaaagataac ggaccagaga
    77041 tcctgcctga aaagcatttg gatattaacg gagaagtaat caatccagta gctcgggatt
    77101 atccagatga gtttatccaa acaggtatct ctgcaatcga tcatttgaat acattagttc
    77161 gtgggcaaaa attaccagta ttttctggct ctggtcttcc tcataaagaa ttagctgctc
    77221 agatcgcgcg acaagcaacg gtactcgatt catcagatga tttcgccgta gtctttgctg
    77281 ctattggaat cacttttgaa gaagctgaat ttttcatgga agattttcgt caaacgggcg
    77341 caatcgaccg ttctgtcatg tttatgaatt tagcaaacga ccctgcaatc gaacgtatcg
    77401 ctactcctcg tatggctttg actgctgcag aatatcttgc ttatgaaaag ggaatgcatg
    77461 ttttggttat catgacagac atgaccaact atgcagaggc attgcgagag atttctgcag
    77521 cacggcgaga agttccagga agaagaggat atcctgggta tctttacacg aacttagcta
    77581 ctttattcga acgagcagga agaatccgcg gactaaaagg atcggttact caaattccga
    77641 ttctaacaat gccagaagac gataaaactc atccaatccc tgacttgact ggttatatta
    77701 cagaaggaca gatcatcttg actagagagc tttacaagag tgggattcag ccaccaattg
    77761 atgtactccc gtctctttcg cggttaaaag ataagggaac tggacccgga aagacaagag
    77821 aagaccatgc agctacgatg aatcagcttt ttgcagccta tgcacaagga aaacaggcaa
    77881 aagaattagc cgtagtttta ggtgaatctg ctttatctga tgtagacaag atctatgcga
    77941 agtttgctga gcggtttgaa aaagaatatg tcaatcaagg attctacacg aaccgttcga
    78001 ttactgaaac acttgatcta gggtgggaac tgctatcgat gttgccaaga accgaattaa
    78061 aacgaatcaa agacgacatg ctggacaaat atctgccaga agggaagtga gttctgatgg
    78121 cacgattgaa tgtgaatccg acccgcatgg aattgactcg attgaaaaaa cagttgacaa
    78181 ctgccacaag agggcataaa ttattaaaag ataagcaaga tgaactgatg cgtcaattca
    78241 tcctgttgat tcgaaagaac aaccagctgc gtcaagaaat ggaagagtct atgacagaag
    78301 caatgtctga ttttgtattg gcaaatgctt cgatcacgga acctttcatc gaagaattat
    78361 ttgttttgcc ggcggaaaac gttgatttgt ctatcgtaga caaaaatatc atgagtgtaa
    78421 aagtacctgt gatgaatttt gaatatgatg aacagctgac agacacacct ttggaatacg
    78481 ggtatttgaa ttccagtgcc gaactggatc ggtcaatcga tcggtttact accctgcttc
    78541 caaaactttt ggaactgaca gaaatcgaaa aaacttgtca actgatggcg agtgaaatcg
    78601 aaaagacacg tcggcgagtc aatgcattag aatatatgac gatccctcaa ttagaagaaa
    78661 cgatctatta tattcgtatg aagctggaag aaaacgagcg cgcagaagta acaaggttga
    78721 tcaaagtaaa aaatatgggt accactgact aagtggtatc tttttttaaa agaggaaaac
    78781 gatgattaaa caaagcaaac aaataaagaa acgtttgccg gctgttcagc ttctcgcatt
    78841 aggatttttt ctcctgattt tagttggcgg cggcctactt accctaccat tttttagtaa
    78901 tagtgggcat gggacaaatt ttatcgatgc gcttttcact gcaacttctg ctgtctgtgt
    78961 aacgggattg acaacattga atacagcaga gcattggaac agtgctggtc aatttttgat
    79021 catgcttttg attgagatcg gcggtcttgg ttttatgatg gttccgattc tatgctttgc
    79081 attgataaag aagaaagtca gtctcagcac acgtattata ttaaaagaag cgctgaatct
    79141 agaagaagta tcaggtgtga tgaagctcat gctttacatc ctaaaattgg cctttgtgat
    79201 ccaattgatt ggtacggttg ctttatcttt tgtatttgtg cctgaatttg gctggttgaa
    79261 aggtatctgg tacagtttgt tccatgcaat ctctagtttt tgtaatgcag ggtttgattt
    79321 gttaggagac agtttagcca atcaccagca aaatgtttat ttgatcatgg tggtatctgc
    79381 tttgatcatt tctggtgggt taggcttcat cgtatggcgt gatttactgg aatatcatca
    79441 gaaaaagaag atgacgattc attcaaaaat cgcattaacc gttacaggta cccttttatt
    79501 aggcggattc gttgtgttct ttttcacaga gcgcaatggg gcaacgctag tggaagggaa
    79561 tatgtttcaa cgattggcaa acaccttttt tatgagtgtg acacctagaa cggctggata
    79621 ttattcagtt gattacctcc atatgagcca tgcaggtctg attttaacga tgtttttgat
    79681 gtacatcggc ggaacatctg ggtcgacggc cggcggattg aaaacaacta cgttaggtgt
    79741 gttgctgatc cagatgcgtt cgatgttgaa aggacgtacg agagcggaag catttggccg
    79801 taccatccga caaggcgcag tgttgcgggc acttacttta ttttttgtta cgttgacgtt
    79861 gtgtgtagtc gccatcatga ttttatcggt gactgaaacg atacctaaaa cttctggcat
    79921 cgaatatatt gcttttgagg tcttctctgc gtttggtaca gtaggtctta cgatgggatt
    79981 gacgccagac ttgactgcaa tagggaaatt gatcattata gcgcttatgt acattggacg
    80041 agttggtgta ttgactgtgg tcttctctct gatgacaaaa gcacaaagaa cacaatcaaa
    80101 atacaaatat ccagaagaaa gtgtcatgat tggataattt catcttctga cagaaaccta
    80161 gtgatttagt aaaataagaa aataaaataa tttttcttgc ttcttggata ctttaagtgc
    80221 aaaatgttcg tttatttttt gaggcactac ccgttgttga acctcgggta gtgcctcttt
    80281 tttattgaaa ggaatcaata agatttgatt cctttattta tcaataggtt ataattcata
    80341 tttttttatt ttttctttta cgatacttag tccagaagct aaaatttcaa ggttattaga
    80401 ggatagggaa attcgaacga atgcatctgg ttgcgtacgt gtagtaaagc gtctggaatg
    80461 ataaagtcgg ataccgttag caagaaagtc attctcaatt atcttagggt caatctcagg
    80521 atcaactgga agaattcgat agtaagggac acgattcgtt ggtttttcta ctttgaaaag
    80581 agaatcaaaa agctgattgg ctctttttgt aagacttaat ttagtttcta agatcctatt
    80641 tgcttcattt gaatggagga tttgagtgat gacttccaca tctaatccag aagttttcac
    80701 atttatatta aaaattgctt gttctatctt gctttggaca tgtactggaa ctacaagata
    80761 agcaactcgc aatccagaac aaataaattt tgtcattcca gctaagtaga ttgtttggtt
    80821 aggtaataaa ttttggaaag gaggaatgat cgtatgttga tagtaagttg ttaaaaatga
    80881 atggatatca tcttcaataa cccatagacc ttctttttca atcacttcgg ctaattgctc
    80941 tcgtcttttg tgagagattt gaaaccctat aggattatta caagaaggca taagaaagac
    81001 accatgaatc ttcttttttc tacattcctg aatcaatata tcaggtcgca ttccttgctc
    81061 gtcaaaatca attggaacga tctctaaatg atataactga gccaattcaa tgaaattagc
    81121 gtatgtatat cggtctgttg ctattctatc acctggagag aaaagtgcag aaagtgtgat
    81181 agccaatcca ttttgaacac cggaaacaat agatagagat tctaaggacg gaatgactcc
    81241 ttgagttttt aaccaatttg ctgcagtagt caattgaaaa tttgtgcctt tgggatcttg
    81301 gtaattaagc aaaccaacaa gatttgggtt attactagtt gattgaataa acgggacaac
    81361 gaatttatta cattcttcaa aagaactaac cagaccaaaa tcaatgatat gttcggttac
    81421 ttcattggta gagatggtga tggactcaaa gacattggga gaaataaatg tgccacttcc
    81481 aatattcgta tacagcaaac ctttctcaat tccatattta taagccttgc caacggtagt
    81541 aaaatttaaa tctaaataat cagctagctc tctttgggag ggtaactgag tgtttttctg
    81601 taatttattc tttaaaatat cttgttctaa ttgttgaatc aacgatcgat aataaggacg
    81661 cttcaatttt tgtttgtctg gtcgccaagt taacgggtaa ttgtcataag aattaatagg
    81721 cattttctcc actccttaaa attgtatacc atacaatttt accattgatt gtattgattt
    81781 tagaagttaa tcttttgtga ggagggaatt gtctatgaaa attattaatt ttgaggaagt
    81841 agtagcttct tttagttttg aagaagcgat tcaagtaatg aaaaaatgtt tttttgatta
    81901 tgaaagtggt aaaatcagcc aaaatcctcg attggtggaa attttacctg acggaaaagg
    81961 caaaaatatg tttgcgatga tgcctgctta tttgggggag aacagatatt ttggcacaaa
    82021 agtcattacc gcttttccgg ataatcatca gtatcattta ccttctcatt taggagagat
    82081 tttcttgttt gatgctcaaa acggactacc caaagcattg ataaacgcaa atgcagtcac
    82141 ctggattcga acagctgctg tatctgcgct ggcaacagat tacttagcaa atccgcatgc
    82201 agaaacactt gctttaattg gagctggtca acaagcattg tcgcatttga ctgcgatttc
    82261 taccattcgt cccatcacta cagtgtttgt ttacgatatt ttagaagaaa gacgaaatac
    82321 ttttatcgct aaagctaaaa aacagtatcc taaaataacg tttataaatg caatatcagt
    82381 agaagatgca gtacgtccag cggaaatcat ttgtacgttg acctctagta aagaggcatt
    82441 tcttcaaaaa gagtgggtaa gggaagacgc acatatcaat gctgtgggca catttactcc
    82501 tgatacaaga gagataagta catcgttgat ggaaacttct caaatctatg tagatgatta
    82561 ctcagctgcc ttaacagaaa gcggggacct gcttatagcc atggcagaag gagatttaga
    82621 ggaatcttgt attgttggta cattaggcga attagtttct gagaaaaaaa cattttataa
    82681 aggagaatcg aggccgacga ttttcgacgc agttggtcta gctattgaag atctttgttg
    82741 tgcagaatat atttataaca aattagagaa aggggcttta aaatgaactt agattattac
    82801 gtagttgatg catttgcaga tgaggtgttc aaaggaaatc cagcagcggt ttatgtgcta
    82861 gaagaatggc tgccagaagg tacgatgcaa aaaattgcca ttgaaaacaa tttatctgaa
    82921 acagcattta cagtgaagaa aaaccaagaa tttgagctta gatggtttac gccagatcga
    82981 gaaatcgatc tttgtggtca cgcgacatta gcaacagcat ttgttttatt taactattac
    83041 aaaatacctg atgaaacgat taaattttct actcaaagcg gtaatctatt tgtgacaaga
    83101 attaaagatt attattacat ggattttcct agtattatgc cgaaaaaagt gccgatattg
    83161 tctgaatatg aagaagcgat tggggctaag attaaagaag cctacttagc acgtgattta
    83221 tttttcgtat tagaagatga aaaaacggtg gctaaattgc agccagattt tacagctatc
    83281 aaaaattttg aattaggaat aggagtcatc gtgacagcag aaagtgtgca aaaagacttt
    83341 gtttctagaa ccttctttcc aaaattaaca atcaatgaag atccagtatg tggatcagca
    83401 cattctaatc ttattcctta ttgggcagaa agaatgaata aaacaaaatt gtcagcttat
    83461 caaatgtcat caaggggcgg ggatctagaa tgtgaattaa aagaagatcg tgtgataata
    83521 ggaggaaaag cagttttgtt ttctaaaggt acctcgttta tttgatttct ttcaaatgaa
    83581 ttaaaaataa attggtggag agtggcaacc ttatagctac aatggttgtt aaaaaaagac
    83641 gcaaactttt tcaatttaat gaaaagtttg cgtctcattt taattattgg tgtttgtttt
    83701 ttattcaatc aagagtaaaa tgccccatac taactatcct cggatgactt cgattttata
    83761 accatcaggg tcaatgacaa agtagtaaga aggcgcagtg ccaggtaatc cttttaagtc
    83821 agtaatctca agaccagcag ctttatgttg ctcgtgtaat ttttctagat catcagctgc
    83881 tatagcgata tgaccatagc cgtctcctag atcatacgca ccatgatcat agttgtaagt
    83941 caactctaat tcatagtcat ccccaggaag tgtcaaataa acaagtgtaa atttgttttc
    84001 tggaaaatca cggcggcggc tttcttcaaa accaaatgcc ttttgataaa attcgattga
    84061 tgcttcaaga tctttcactc gaacacatgt gtgagccatt ttcatagatt catctctcct
    84121 tttcctttta ctcaatcata acaaaaagaa gtaaggaaat agttgatttg tgcttgttca
    84181 tgagaaattt ctcatgtaaa atggatagaa aataaaactg ttaaggtgga aactattcat
    84241 ggataaacca atttttggtg aaaaaaagca atttgctgat tatcaaaccc gttatgcagc
    84301 atatattgtc atagaaagag atcagcagat tgcagtaatc gaggctccaa atggtgcttt
    84361 ttttcttcct ggcggggaaa ttgaaggaga agagacgaaa gaagaagcga ttgtccgtga
    84421 gctgatagaa gaaatgggaa ttgtggcaga aatttcttct tatctgggag aagctgatga
    84481 gtatttttac tcgaattatc gtgcaactta ttattataat ccaggatatt tctttgttgc
    84541 tgattcttgg aagcgtatag gagaaccaac tgaaaagacc aataaaattt ggtgggtgag
    84601 ccctcaagaa gcgcttgtga aattgaaacg tggtagccac cgatgggcag tcgagagatg
    84661 gatcgaaaaa aataaaaact gaaagaaagc gagtagatca gctttctctc agttttttta
    84721 tttattacag tacatatttt ttgattgctt cagctacacc gtgctcgtcg tttgatgaag
    84781 tgatgacatt tgctgcttct ttgacaagag aaacggcatt tcccattgct actcctagac
    84841 cagcatattc aatcatggat aagtcgttct cgttatctcc gatagccatg atttcatctt
    84901 gatcaatacc aaggtgctgt gcgagattcg caactgccgc acctttactt gcttctttat
    84961 ttagtacttc gaagtaatag ggcgcacttt tgaccgttgt gtatttatca cggaaagttt
    85021 gcggtaaacg cgcaattgct gcatctaaaa tttctggttc gtcgatcatc atcattttga
    85081 cgatgttcat gtctggtgtc atttcttcag gtgttcgata ttttagcggc atcttgacta
    85141 aacttgcttc gtggatcgta taagcgctga tatctcgatt aggcgtgtag atcgctttgt
    85201 catcgatcga atggagatga ctgccgacac ggcgtgccat cacttcgatc tctaggaaat
    85261 cttcatgtgt cagtccgtga cgggcgatga ttttacctga tttcgtttgt tgtacgagtg
    85321 ccccgttata agtaataacg taatcattat cttgaaaaag gttcaactcg tttaactgtt
    85381 cctggacacc tggtaaggga cggccagtgc ataaaacgat cgaaacacct tttgcaacag
    85441 cagcggcaat cgcttctttt acttcttttg ttacttctct tttctcattt aataaagtac
    85501 catcgatgtc gatagcgact agtttgatag acataatttc ctccaatata ttttaattta
    85561 tttcaatcaa tgcgccatta cggatatggc tggcaaattc ttgataagtt tcgtcaaata
    85621 aatcataatg atcacgcaag gacggatcaa ccatttcttt tggaaagaaa aatcgctcat
    85681 ctccttgttc ttgtcccgct aatgcagcaa caagctgact aacctgtgat aattctatca
    85741 aagttccgtc atttcgcaaa atctcgattt gtgtgcgatg tctgccttgt tctgggcgat
    85801 aaaaatcata aggtagatcg tagctagaat tcacagcagt gtaataaaca ggattatatc
    85861 cgaccttttc tactaacaaa gtgagttctt ggactaattt tgaatcccgg ttgccagaaa
    85921 aagtagcaga tttcagtggt ttacgattca aaaaacgttt agctaaatca tttaaaatag
    85981 gatcagcaga ttcagaccat tgagtaaagt aagtgcccaa gaccccatca tcaagtttga
    86041 ggtattcttc taaagtaaag cttccgtcaa gaaatggcag aagtaattga gaatggagtt
    86101 caaaactgct ggcatcttct tgatacaact cgtgtgcgcg atgaagcaga tgctccaaaa
    86161 ttacttccat accacgggaa acaggatgga agtacacttg cacatacatt tgatatcggc
    86221 taacgatata atcttccact gcatgcatgc cactcatgga aaaagcgatc ccgccttcat
    86281 aaggacgaat cacacgtaat attcgggtaa gatcaaatgt tccatattct gttccagtga
    86341 aataagcatc ccgaagcaaa tagtccattc gatctgcatc gatctgacta gaaatcattt
    86401 ggacaacttg tgggttgggg taagtttttt ggatcacact agctaccttt tcaggaaaac
    86461 cttcttctac tcggttaaga atctgataca cttctgtttc tggagaagtg atgatctcta
    86521 cagtgatggc ttcatgattc gtatggaaga tatgttcaaa tgtatgagag taaggaccat
    86581 gaccgacatc atgcaacagt gccgcacata aagtcaccag ccgttcctga tcatcccagc
    86641 ctccgttgcc tattttttct tttgaaaaat ttcgagaaaa gatatcgcag attcgtcttg
    86701 aaatctcata aacgcctaat gaatgagtaa aacggctatg ttctgctccg tgaaaagtga
    86761 aagaagaagt gcctaattgt ttaatgcgtc gtagacgttg gacttctttc gaattgatca
    86821 aatctaagat tacttgatgc tggacatgga tatagttatg gactggatca cgaaaaactt
    86881 tttccatagg cagcatttga tatttataag gggttgtcat aatgtagctc ctttatgtta
    86941 ttacgttgtt ccattctctg gatttggttg ttccattgct ccagctggat ttcttttttt
    87001 agccagtcgg tagaatcctg taaatcactt gcagaataca gcttttcaaa agcttttgca
    87061 aatgcttctt tgacttcttt tacaaaaagg ggttggtcaa gcagttcttc aagtgttgcc
    87121 attgtagcag gatccactgc aggatagcca tttgtaccaa agtcttcttt taaagcagat
    87181 tgataaaatc gcttcatgac ttgcccgcgt ttttcctgat taccgttgac acttaagtac
    87241 atcataacag aaatcccatt tttgatccga cgctgagcga taccggcaaa ttttttgcca
    87301 tggatgctta aatcataagt tccaggacaa taagaatggg tgatttcgaa tgcttgtatc
    87361 ggtgcctttg gaaaagcgta tttagtcaat aggagcattt gctcgtaagc gtcatctatg
    87421 gttatttttt ttgtgtcact ttgggggaaa atcaaagaaa tattcaaaat tccttcatct
    87481 gatacgatcc ctaatccacc tgaatttctg atcactggag cgtaacctgc atctttcagt
    87541 gtttggatcc cgtcacttag aaaaggagtt cgaacatcct tcatacctaa gatgactgtg
    87601 cagtcatatt gccagaaatg taaaaagatt tgctggtgtt ctttagaata ttccgttaat
    87661 atatctgtta atgcaaaagg ggaaaagtcg tttttttgat aaatgtgctg atctagtcga
    87721 atcgcagggt tcattcaacc ggctcctttg tataaattca tattttctac aatattatac
    87781 tctaaaatca aagagttgtt ttggaaaaaa ggttttctgt aaaaatggac aagttggttg
    87841 acaaaacaaa agaaactagg aacaatgtag ctatgagaag taaaggagaa tgaataatgg
    87901 aattatcaca aggaacaccg atttcaatca aattgcgtac aaaagtaaaa cagcaagggg
    87961 aagtgcaaga tttttatttt gatttgaaag ggcaaatggt gacaattggc gatacgctgt
    88021 acatacgtta taaagagatt caggaggaga cgggcgatga gattcctgta acgatcaaat
    88081 tagttccaga tggtcatgta cagctgatcc gtgcaggaga aatgcggatg cgtttgaaat
    88141 ttggctataa agaacggtta gaaacatcct atcgaacacc atacggtatg atccagattg
    88201 ctacttttac gaaagaactg catgttagtt tgaaagaccg tcccacagca gggaaggttc
    88261 gaatcgatta tgatctgttc atgggaccgg aaaaaatcgg cgaatattat ttgaccttgg
    88321 attttacagc gtaaatataa aagaaaagtt tgattttttg tgtctgattt tgtatgataa
    88381 ggagtagact gtgaaaggac gtgtcctgat tggaaattag tgtatttgaa ggtgcaaaca
    88441 aaagcgaatt atcaatgatc gaagtagcac acgcgatctt agaacaacgt ggcgatgtca
    88501 tggatttttc tgatttagct aaccagatcc aaaactatct tgggaaatca gacagtgaaa
    88561 ttcgtgattc actcgcacaa ttttatactg acttgaatat tgacggcagc tttatctcat
    88621 taggggataa tcgttggggc ttgcgttcat ggtatgctat cgattcgatc gatgaagaag
    88681 taaaccatgg aatggacgaa gaggatgaag atactccacg tcgccgtaaa cgcaagaaag
    88741 tcaacgcctt tatcaatgat gatgaagacg cgatcgatta caatgacgat gacccagaag
    88801 atacagatct gacagaagaa gatgacgatg atctgtttga tgacgatgat gatgaagatg
    88861 aagaaatcgc tgcttataat tctgacttgc aagaaatcgg agcagatgac ccgacagatg
    88921 atgaagaaga cttgccagga aatatcgaag aagatttaag tatcatagac gaagacgatg
    88981 atgatgaaga ttatgaagag gaagaatttt ctgactctga aaaagaataa acattatttt
    89041 cttacgagag gttgtgacag agacgatcag cctatcagaa taaggaggtg tgacacgatt
    89101 tttgtcacac cttctttttt gtatataaaa atcccaagta aatacataaa aaataaaaaa
    89161 attgaaactt ttagcgcacc ttgtacgtca tattaagtga ggcagaaagg agtggagaat
    89221 gatttttact ggatataaga aaaaacggca gatcgaaaaa taccgtcacc tgctgaatgg
    89281 actcatcgaa actgattatc aaaaaatgtt ccgtatcacg atgaattacg tacatgataa
    89341 agaagaggcc ttagatgtga tgcaagatag ttttcataaa gccctgaact attttgaaaa
    89401 agaaaaagag atcgagcatt ttagtgcatg gttttatcgg atattgatcc gcacggcatt
    89461 agatagttgg cgcagacaaa aaaggacgcc tgtggactta tttgaaattc aagatatccc
    89521 ccaacagtta cctttagaaa cttccgttgc agagctccat atgattttag ataaaataga
    89581 cagtccggaa aaagagattc tgatcctcta cttttttgaa ggatttcgtt tgaaagaaat
    89641 tgcgactatc ttggatatga atgaaaacac agttaaaacg aaaatgtacc gctcattgaa
    89701 tgctttacgt caaatcctag aatgaaggag agaagagtgc catgtattcc caaaaagaaa
    89761 atttaaaaaa actaaagaaa acttataaag aacaagcaat tcccaaaggg cttaaagagg
    89821 agatccgcca gcgttttatt atcgaagagc aatcatttat aaaagcaaag cggagaaaga
    89881 gacgtctcca agggttcgga gtatctttgg ctatcgtaat gattacaaca agtagccttc
    89941 tttttaatag tcaagttcga agctttgcag aagatttacc catcttagga tcagtcattg
    90001 aattgatctt aggcgaacgc tttactgatc gatctgaaaa aatcgatatt caggtaccga
    90061 agatcaatac acaaaatgag aaagaaaata aaacaattca tggattaaat caaaaatact
    90121 ttcgcgaagg acaagcagat tttgaaaaag ctgaaaaaga atatggaaat tttgaaacgg
    90181 atcattacca agttttggga gattatcaga aaatcgtaga cgataaccgg tttctcgtga
    90241 ttgaaaggca gatcacccaa acagcagcag atagccatgt tgaaaaaaga tacgacacaa
    90301 tcgacaagaa aaacagtgtc cagctctcac ttccactttt attcaaagat gacacctatc
    90361 tatctgtttt gacaaaagaa gtcaaacggc agatggccga acaagtcaag gaagatccat
    90421 ctaagtacta ttggactgag caagatattc aagaagggac gatagaaaaa ccaacacttg
    90481 ttacgcctac acgaagtttt tatttgaaca aagagcatca attagttttg actttttctc
    90541 aatacgaaat tgctcctggt tatatgggta caccagaatt tgtcattcct aagtccgtga
    90601 caaaaacgat tttggcatcg gaagattatt tggatcatta gacgagaagt agttgcgact
    90661 agcagtttca attttcaagt aagtacaagt aaataataag aagagaaaaa gagaaagaag
    90721 agatatagtg aaaagaaatt atttagttat cagtattatt gctttatccg tgcttttgtt
    90781 tttcgaaatt acttcggtgg cctccttgat caccgaagta aaaggacaaa cacactcttc
    90841 ggagcattcg tcacaatctt tcaaacaatc agaacaatca accattaaaa gccaatcaac
    90901 tgaaacagct aacgtcaaag aagccattca agaatcagcg gaaaaggtac aaagtcagtc
    90961 atcacaatca acacaagaca gtacaaaaac gagccgagat ccggctgtca aaagcgtcgc
    91021 aatcagcttt gatgatggac caggagcgac cacaacaccg cagcttctgc gaatcttaaa
    91081 agaaaaaaac gtgcatgcca cttttttcgt cttaggagaa aatacggcgc agcatcctga
    91141 aatcgtgaag cagacagctg aagcagggca cgagattggc aatcacacat acgatcatca
    91201 gaatctggcc actctttctg cccagtcgat gacggaggaa gtgacgaaag cagacactga
    91261 gatcaaaaaa gtcactggca aaacccccac ttttgttcgt ccgccctatg gttctgtcac
    91321 gaatgtagga gcaacgatca tccagcgacc gatcatcgaa tggtctgttg attcagaaga
    91381 ttggaagaca agaaatcctg atttgatttt gcagaagatc caagcaacag tatacgatgg
    91441 ggcaattatt ttattccatg atatctatcc tgaaacgatt cgtgccgttc ctcaagtgat
    91501 cgattatctg aaagagcaag ggtatcgcat cacgacagtt ggggatttat tagggcatcc
    91561 aacggctgtc gagaactatt atggcagaaa cgatcatcgg ccagttcagt aagtgagaca
    91621 agtatcttta ataaataaca cattttaata agtagttgaa cacataacta ccttacttgc
    91681 aaaggcttaa caatatctat acaggtacaa caaaaaactg tccaccaatt ttctttggcg
    91741 gacagttttc acttaaaaat aaagaagcaa ctattcgtaa attatgctaa aatagcagta
    91801 gaacgcgtcc tgagggaatc gaacccccgt ctcaagaacc ggaatcttac gtgatatcca
    91861 ctacactaag gacgcaagca ctgggataat tgtaactaaa cagataaaaa attacaaggg
    91921 gattggacaa aaaaatgaaa tttgagcaaa atttttcaca aaaacagcag cagacacaga
    91981 aactagccat gacgcaacag ttgcaacagt ccatccaagt tttacaatat aacagtgagg
    92041 agctgttggc attcgttgag aatcaagcaa tggaaaatcc attggtggaa gttgttgagc
    92101 cggaatggca gccagattac ataaaagctt cttcatcttc ttatgaagga gaagagacaa
    92161 attacctaaa tcagattcct gatacaaaag ggtctttatt tgattcattg atcgaacaag
    92221 tccatttgaa ttaccgagat acttttttga ggaaaatcgt tctttatctt gtagaataca
    92281 tcgatttgaa cggatttttg acgattagtt tagaagaagc cggaaaagag attggagcta
    92341 cgcctatcca aatgctcgat gcgttgactc tgattcagca attagaacca gctggagtag
    92401 gtgcacgtag tttgcaagaa tgtctcatgc ttcaaacaga acgagatgat tatgcgccgg
    92461 aattagctta tatcgtgttg gaagaatgtt ttgaggaact ggtggagcga aaatggaaag
    92521 aaatcgcaca acgtttttct gttgatctac atgctgttca gcagatattc gactatttac
    92581 aaacgttgag tccaagccct ggccggattt tcgaccgtag cagcgaattg tacattattc
    92641 ctgatgtccg ggtattagtg gacgacgata aaaatgtaca agttatctca aaccgaaaaa
    92701 atcagccaaa tatacgcttt caagagagtt acttcaaaca aatgtcacaa caagcagata
    92761 aagaaactga aaattattta aaagaacgga aacaggaatt cgaatggttg aagaaaacga
    92821 tcctacaacg tggggataca attttgcggg ttgctcaagt cattgtttcc cggcaaaaag
    92881 ctttctttat cgacaaggaa cgtccaatca agcctcttac gttaaaggaa gttgcaactg
    92941 agatagatgt gcatgaatcc acggtcagtc gtgcagtcaa cgggaaatat ttggaaacag
    93001 acttcggtgt atttgaatta aaaaaatttt tcactacacg aattcctacg aatagtacag
    93061 aacagacaga agacctttca gcagatacag cgaagaaaaa gctgcaggaa ttagtcgatc
    93121 aagaagacaa aaacaagccg ttgtctgacc agaaattggt tgaattgctg aaaaaagatg
    93181 agatagcgat ctcaagacga acagtagcaa aatatcgtga tttattagga atcccgagtt
    93241 catcaaaaag aaaacgttat gataactaat cagtcaaaag actagaaaaa gtatttcact
    93301 ttttctagtc tttttagttg aaaaacgaga gcaaaactgt tagacttaca gtcgtgaggt
    93361 tgagatttcc ctttattgat gtgaaattcg aatagttaat ttcttttttt atcgtatatg
    93421 ggtcgtttta agtctacatt ggacgtaaag tgtccaacta aggagatcgc tatgctggat
    93481 gaaataaaaa tgattgaatc tgttgcacca gatattatcg aagtgttgca agaacgctat
    93541 aaaattttac gaaatatcta ttggatgcag ccgattgggc gtcgaagttt atcggaaagt
    93601 atggggatca cagaacgagt cttacgaaca gaaacagacc ttttgaaaaa tctgaatttg
    93661 atcgacacct caaaaagcgg tatgacgctg acaactaagg gcgaagaagt ttatcaaagc
    93721 cttgaaaact tcatggatca gcttttaggt acgcatcaaa ccgaacaaca gttggcagaa
    93781 tattttggta accaacgctg tatcgttgtt tcaggaaaca gcgaagagca gaccaaagtg
    93841 gctgatgcat tcggcgaagc gctgagcgaa gccttagacc gactacttcc agaaggcgag
    93901 aatatcatcg ctgtgatggg aggaactact atggctgtgg tagccgaaca attgtctaat
    93961 ctggaaaata agaaacggca taacctgttt gtccctgcaa gaggcgggat tggtgaagcg
    94021 ataactgtac aggcaaattc tgtcagtgca agaatggctg ctaaagcaaa cggtaaccac
    94081 cgcgcacttt atgttccgga acaattaagt ctggcaactt acaattcttt actcaatgag
    94141 ccatctatcc aagaagtctt aaacttgatt agtgaagcga attgtgttat tcatagtatt
    94201 gggcgtgcat tacacatggc agcacgtcgt aagatgactg aaaaagaatt agtcatgctg
    94261 aaacaagcaa atgctgttgc ggaatctttt ggctactttt tcaatgaaaa aggtgaagtc
    94321 gtttataagg tccctagaat cggcatagaa ttgcaagatt tggaaaaagt cccgatcatc
    94381 atggcaatcg cgggcggaaa atcaaaagct aaagcaattc gagcttatat gaaaaatgca
    94441 ccaaaacaaa cgtggctcat cactgatgaa gctgctgcaa atgagatttt aaaaggggta
    94501 accctttaaa ataaatattt ttttgatttt cataaggagg aaatcttaaa tgacagttaa
    94561 agtaggtatt aatggttttg gacgtattgg acgtctagca ttccgtcgta tccaagatgt
    94621 agatggaatc gaagtagtag caatcaacga cttgacagat gctaaaatgt tggcacactt
    94681 gttaaaatac gacacaactc aaggacgttt caacggaaca gttgaagttc atgaaggttc
    94741 attcaacgta aacggaaaag aagttaaagt attagctaac cgcaacccag aagaattacc
    94801 atggggcgaa ctaggcgtag atatcgttct agaatgtact ggtttcttca cttctaaatc
    94861 agcagctgaa aaacatttaa cagctggtgc taaacgcgtt gttatctctg ctcctggcgg
    94921 aaacgatgtt ccaacaatcg tttataacac aaaccacgaa acattaactg gtaaagaaac
    94981 agttatctca ggtgcttcat gtactactaa ctgtttagct cctatggcta aaacattgaa
    95041 cgacaaattt ggtgttgttg aaggattaat gacaactatc cacgcttaca caggtgacca
    95101 aatgactcta gacggacctc atcctaaagg tgacttccgc cgtgcacgcg ctgctgctgc
    95161 aaacatcgtt cctaactcaa caggtgctgc taaagctatc ggtttagtaa ttcccgaatt
    95221 gaacggtaaa ttagacggag ctgctcaacg tgttcctgta ccaacaggtt cattaacaga
    95281 attagtaaca gttcttgaaa aagaagtaac tgttgacgaa atcaatgcag caatgaaaga
    95341 agcttcaaac gaatcttacg gatacaacac agacgaaatc gtttcttcag atatcgttgg
    95401 tatgacttac ggttcattat ttgatgctac acaaactaaa gtaatgacag ttggcgacaa
    95461 acaattagtt aaaactgttg cttggtacga caacgaaatg tcatacactg cacaattagt
    95521 acgtacttta gaatacttcg ctaacttata agatagacaa acgtacaagt gtaaattata
    95581 gacatgtaca tttaaaagcg gggaagcaat cgcgcttctt ccgctttttt tgataataag
    95641 tttattcagg aggaaataaa atggctaaga aaacagtgaa agatatcgat ttaaaagaca
    95701 aaaaagttct tgtccgtgtt gacttcaacg ttcctttgaa agacggcgtg atcactgacg
    95761 acactcgtat caaagcagca ttgccaacaa tcaactacgt tctagaacaa ggcggaaaag
    95821 caatcctttt ctctcacctt ggacgtgtaa aaacagaaga agataaagaa ggaaaatctt
    95881 tagctccagt tgcaaaacgt ctaggcgaat tattaggtaa agaagtaaca ttcgtacctg
    95941 aaactcgcgg agaacaatta gaagaagcaa tccgcaacat gaatgacggc gacgttgtcg
    96001 tattcgaaaa tacacgattt gaagatattg acggtaaaaa agaaagcaaa aatgatacag
    96061 aactaggtaa atactgggct tcattaggcg atgtatttgt taacgatgct ttcggtacag
    96121 ctcaccgtgc acatgcttct aacgtaggta tcgcttcaac tggtatccca acagttgctg
    96181 gattcttgat ggaaaaagaa atcaagttca tcggtgaagc agtagaagaa ccaaaacgac
    96241 caatgattgc aatccttggt ggcgcaaaag tttctgataa aatcggcgta atcgaaaact
    96301 tgattcctaa agcagataaa atcttgatcg gtggcggaat gacttacaca ttctacgaag
    96361 caaaaggaat caagatcggt aactctctag tagaagctga taaagtggaa ctagcaaaag
    96421 aattaatcga aaaagcaggc gacaaacttg tcttgccaat cgacaatgtc tgtgcaccag
    96481 aattttcaaa tgatgttgaa acacaagtaa tcgaaggaga cattcctgat ggtttgatgg
    96541 ctttagacat cggcccagca tcagtaaaat tatttgctga tacattacaa ggtgcaaaaa
    96601 cagttgtttg gaacggacct atgggtgtat ttgaaatgag taactttgct aaaggtacaa
    96661 tcggtgtttg tgaagcaatc gctaacttag aaggcgcaac aacaatcatc ggtggcggag
    96721 actcagccgc agcagcagaa caattaggat ttgctgacaa attcacacac atctcaacag
    96781 gtggcggcgc aagcttggaa ttgcttgaag gtaaagaatt accaggacta gcagcaatca
    96841 acgataaata aacgaccaag tttgctcaat tctgacgagt aatcgaacaa aaggtgaagg
    96901 gagttttcat gactccctag ccatttttca ataaattaag gagtgtgttc ctcaatgcgt
    96961 aaacctatta tcgcaggtaa ctggaaaatg aacaaaactg catcagaagc aaaagaattt
    97021 gctgaagcag taaaaaacaa aatcccttca aatgacaaag ttgattcagt catcggatct
    97081 cctgcattat tcttacaaga attaatgaca tcagctgaag gtacagaact aaaaatctca
    97141 gcacaaaact gctactggga aaactcaggt gcgttcactg gtgaaacttc accagcagct
    97201 cttgctgatc taggtgttca ttatgtgatc atcggacatt cagaacgtcg tgaatatttc
    97261 catgaaacag acgaagacat caataaaaaa gcgaaagcta tctttgcaaa tggtatgaca
    97321 ccaatcctat gctgcggcga atctttagaa acctatgaag caggcaaaac tgctgaatgg
    97381 atcgaaggac aaattacagc tggtttagct gatctttcag ctgaacaggt gtcaaacatg
    97441 gttattgctt atgaaccaat ctgggcaatc ggtactggta aatcagctga cgcacaaatc
    97501 gctgacgaaa tttgtggagt tgtacgtcaa acagttgaaa aactttatgg aaaagaagta
    97561 tcagaagcag ttcgtatcca atacggcggt tctgtaaaac cagaaaatat tgctgaatac
    97621 atggcaaaag aaaatgttga cggtgcttta gtcggtggcg caagcttgca agcagattca
    97681 ttcttgtcat tgttagacgc tgtaaaataa ttgttgaaaa tttgcgaaaa atgcaagaaa
    97741 tgtttgcact aatgagcaaa attaactaaa atcgtatatg agggaaatcc cttaggaaaa
    97801 aacaaactca aaggagagac aaaacatgtc aattattact gatgtttacg ctcgcgagat
    97861 cttagactca cgtggtaacc caacaatcga agtagaagta tacacagaaa gcggagcttt
    97921 tggccgcgga atggttcctt caggtgcttc aactggtgaa tacgaagcag ttgaattacg
    97981 tgacggagac aaagctcgtt atggcggtaa aggtgtaact aaagctgtcg acaacgtaaa
    98041 caacatcatt gctgaagcaa tcattggcta cgatgttcgt gaccaaatgg ctatcgacaa
    98101 agctatgatc gctttagacg gaactcctaa caaaggtaaa ttaggtgcga acgctatttt
    98161 aggtgtttct atcgctgttg cacgtgcagc tgctgactac ctagaagtac ctttatacca
    98221 ctacctaggc ggattcaaca caaaagtatt gccaacacca atgatgaaca tcatcaacgg
    98281 cggatcacat gctgataact caatcgactt ccaagaattc atgatcatgc ctgttggcgc
    98341 tccaacattc aaagaagctc tacgtatggg tgctgaagta ttccacgcat tagcttcaat
    98401 cttgaaagct cgcggattag caacttctgt tggtgacgaa ggtggatttg ctccaaacct
    98461 tggttcaaac gaagaaggtt ttgaagtaat catcgaagca atcgaaaaag ctggctatgt
    98521 acctggtaaa gacgttgttc ttgctatgga tgctgcttct tcagaattct acgacaaaga
    98581 aaaaggtgtt tacgtactag ctgactcagg cgaaggcgaa aaaacaactg acgaaatgat
    98641 caaattctac gaagaattag tttctaaata tccaatcatc tcaatcgaag atggattaga
    98701 cgaaaacgac tgggacggat tcaagaaatt aactgacgta ttaggcgaca aagttcaatt
    98761 agttggtgac gacttgttcg taacaaacac tcaaaaatta tctgaaggta tcgaaaaagg
    98821 aattgctaac tcaatcctta tcaaagtgaa ccaaatcggt acattaacag aaactttcga
    98881 agctatcgaa atggctaaag aagctggcta cacagcagtt gtatctcacc gttctggtga
    98941 aacagaagat tcaacaatct ctgatatcgc tgttgcaaca aacgctggcc aaatcaaaac
    99001 tggttctcta tcacgtactg accgtattgc taaatacaac caattactac gtatcgaaga
    99061 ccaacttggt gaagttgcag aatacaaagg tttgaaatct ttctacaact taaaaaacaa
    99121 ataattcttt tctaatgaag atacatgatc gactattgaa agatagtcga gtatgatcac
    99181 ttagttaagt aatcgaactc tctacttgct gaa
//
LOCUS       DBBGSP010000004        77202 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000004 DBBGSP010000000
VERSION     DBBGSP010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 77202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.004"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..699)
                     /locus_tag="ACIZE9_000340"
     CDS             complement(<1..699)
                     /locus_tag="ACIZE9_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HGC6092235.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGI"
     gene            complement(770..1231)
                     /locus_tag="ACIZE9_000341"
     CDS             complement(770..1231)
                     /locus_tag="ACIZE9_000341"
                     /inference="COORDINATES: protein motif:HMM:NF025639.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HGC6092236.1"
                     /translation="MFQILKLSKNEIRHSNFLAFLFAPNETHNLSDEFFKMFLKRYID
                     SNDDTKAAINYFDALLNSYEDLIVYRENKNIDILLVSEKNKIVVCIENKILSSESGGQ
                     LNKYQIYIERNYSNYKKIFVFLTPDGNEPTNPSWGIITYKNIVEESVKYFV"
     gene            complement(1195..1320)
                     /locus_tag="ACIZE9_000342"
     CDS             complement(1195..1320)
                     /locus_tag="ACIZE9_000342"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092237.1"
                     /translation="MIDEKKCLKNLLEDMDDIEENYLNGLGKQIYFRYLSYLKMK"
     gene            complement(1523..2002)
                     /gene="rlmH"
                     /locus_tag="ACIZE9_000343"
     CDS             complement(1523..2002)
                     /gene="rlmH"
                     /locus_tag="ACIZE9_000343"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGC6092238.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            2430..3719
                     /locus_tag="ACIZE9_000344"
     CDS             2430..3719
                     /locus_tag="ACIZE9_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HGC6092239.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(3758..4363)
                     /gene="ytpR"
                     /locus_tag="ACIZE9_000345"
     CDS             complement(3758..4363)
                     /gene="ytpR"
                     /locus_tag="ACIZE9_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGC6092240.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(4568..5032)
                     /locus_tag="ACIZE9_000346"
     CDS             complement(4568..5032)
                     /locus_tag="ACIZE9_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGC6092241.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(5054..5374)
                     /locus_tag="ACIZE9_000347"
     CDS             complement(5054..5374)
                     /locus_tag="ACIZE9_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGC6092242.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(5518..6597)
                     /gene="pepA"
                     /locus_tag="ACIZE9_000348"
     CDS             complement(5518..6597)
                     /gene="pepA"
                     /locus_tag="ACIZE9_000348"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGC6092243.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            6797..7147
                     /locus_tag="ACIZE9_000349"
     CDS             6797..7147
                     /locus_tag="ACIZE9_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HGC6092244.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            7370..8317
                     /locus_tag="ACIZE9_000350"
     CDS             7370..8317
                     /locus_tag="ACIZE9_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC6092245.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(8374..9792)
                     /gene="pepV"
                     /locus_tag="ACIZE9_000351"
     CDS             complement(8374..9792)
                     /gene="pepV"
                     /locus_tag="ACIZE9_000351"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGC6092246.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            9941..10786
                     /locus_tag="ACIZE9_000352"
     CDS             9941..10786
                     /locus_tag="ACIZE9_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGC6092247.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            10790..11230
                     /locus_tag="ACIZE9_000353"
     CDS             10790..11230
                     /locus_tag="ACIZE9_000353"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HGC6092248.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            11280..11474
                     /locus_tag="ACIZE9_000354"
     CDS             11280..11474
                     /locus_tag="ACIZE9_000354"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092249.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            11610..12287
                     /locus_tag="ACIZE9_000355"
     CDS             11610..12287
                     /locus_tag="ACIZE9_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6092250.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTRFRWLR
                     LTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDYFED
                     IQDRPIK"
     gene            complement(12695..13384)
                     /locus_tag="ACIZE9_000356"
     CDS             complement(12695..13384)
                     /locus_tag="ACIZE9_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092251.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(13359..15488)
                     /locus_tag="ACIZE9_000357"
     CDS             complement(13359..15488)
                     /locus_tag="ACIZE9_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HGC6092252.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            complement(15536..16873)
                     /locus_tag="ACIZE9_000358"
     CDS             complement(15536..16873)
                     /locus_tag="ACIZE9_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HGC6092253.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(17125..17484)
                     /gene="rplT"
                     /locus_tag="ACIZE9_000359"
     CDS             complement(17125..17484)
                     /gene="rplT"
                     /locus_tag="ACIZE9_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGC6092254.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(17537..17737)
                     /gene="rpmI"
                     /locus_tag="ACIZE9_000360"
     CDS             complement(17537..17737)
                     /gene="rpmI"
                     /locus_tag="ACIZE9_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGC6092255.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(17809..18333)
                     /gene="infC"
                     /locus_tag="ACIZE9_000361"
     CDS             complement(17809..18333)
                     /gene="infC"
                     /locus_tag="ACIZE9_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGC6092256.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(18377..18502)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            18653..19285
                     /locus_tag="ACIZE9_000362"
     CDS             18653..19285
                     /locus_tag="ACIZE9_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HGC6092257.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(19287..20192)
                     /locus_tag="ACIZE9_000363"
     CDS             complement(19287..20192)
                     /locus_tag="ACIZE9_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGC6092258.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(20277..20936)
                     /locus_tag="ACIZE9_000364"
     CDS             complement(20277..20936)
                     /locus_tag="ACIZE9_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HGC6092259.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            21252..22196
                     /gene="mvk"
                     /locus_tag="ACIZE9_000365"
     CDS             21252..22196
                     /gene="mvk"
                     /locus_tag="ACIZE9_000365"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGC6092260.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            22189..23166
                     /gene="mvaD"
                     /locus_tag="ACIZE9_000366"
     CDS             22189..23166
                     /gene="mvaD"
                     /locus_tag="ACIZE9_000366"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGC6092261.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            23179..24264
                     /locus_tag="ACIZE9_000367"
     CDS             23179..24264
                     /locus_tag="ACIZE9_000367"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGC6092262.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            24261..25325
                     /gene="fni"
                     /locus_tag="ACIZE9_000368"
     CDS             24261..25325
                     /gene="fni"
                     /locus_tag="ACIZE9_000368"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGC6092263.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(25574..26377)
                     /locus_tag="ACIZE9_000369"
     CDS             complement(25574..26377)
                     /locus_tag="ACIZE9_000369"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGC6092264.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(26397..27239)
                     /gene="kduI"
                     /locus_tag="ACIZE9_000370"
     CDS             complement(26397..27239)
                     /gene="kduI"
                     /locus_tag="ACIZE9_000370"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HGC6092265.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(27255..28262)
                     /locus_tag="ACIZE9_000371"
     CDS             complement(27255..28262)
                     /locus_tag="ACIZE9_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HGC6092266.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(28269..28913)
                     /locus_tag="ACIZE9_000372"
     CDS             complement(28269..28913)
                     /locus_tag="ACIZE9_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HGC6092267.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(29013..29771)
                     /locus_tag="ACIZE9_000373"
     CDS             complement(29013..29771)
                     /locus_tag="ACIZE9_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HGC6092268.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(29898..31049)
                     /gene="fucO"
                     /locus_tag="ACIZE9_000374"
     CDS             complement(29898..31049)
                     /gene="fucO"
                     /locus_tag="ACIZE9_000374"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008912 - lactaldehyde reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HGC6092269.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(31131..31442)
                     /gene="rhaM"
                     /locus_tag="ACIZE9_000375"
     CDS             complement(31131..31442)
                     /gene="rhaM"
                     /locus_tag="ACIZE9_000375"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HGC6092270.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(31444..32289)
                     /gene="rhaD"
                     /locus_tag="ACIZE9_000376"
     CDS             complement(31444..32289)
                     /gene="rhaD"
                     /locus_tag="ACIZE9_000376"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008994 - rhamnulose-1-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HGC6092271.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(32303..33559)
                     /gene="rhaA"
                     /locus_tag="ACIZE9_000377"
     CDS             complement(32303..33559)
                     /gene="rhaA"
                     /locus_tag="ACIZE9_000377"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HGC6092272.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(33556..35016)
                     /gene="rhaB"
                     /locus_tag="ACIZE9_000378"
     CDS             complement(33556..35016)
                     /gene="rhaB"
                     /locus_tag="ACIZE9_000378"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HGC6092273.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            35169..36038
                     /locus_tag="ACIZE9_000379"
     CDS             35169..36038
                     /locus_tag="ACIZE9_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGC6092274.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(36164..37063)
                     /locus_tag="ACIZE9_000380"
     CDS             complement(36164..37063)
                     /locus_tag="ACIZE9_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092275.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(37228..38052)
                     /locus_tag="ACIZE9_000381"
     CDS             complement(37228..38052)
                     /locus_tag="ACIZE9_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HGC6092276.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(38063..39358)
                     /locus_tag="ACIZE9_000382"
     CDS             complement(38063..39358)
                     /locus_tag="ACIZE9_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HGC6092277.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(39374..39853)
                     /locus_tag="ACIZE9_000383"
     CDS             complement(39374..39853)
                     /locus_tag="ACIZE9_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HGC6092278.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(39859..40887)
                     /locus_tag="ACIZE9_000384"
     CDS             complement(39859..40887)
                     /locus_tag="ACIZE9_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HGC6092279.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(40904..42010)
                     /locus_tag="ACIZE9_000385"
     CDS             complement(40904..42010)
                     /locus_tag="ACIZE9_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGC6092280.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(42239..44836)
                     /gene="adhE"
                     /locus_tag="ACIZE9_000386"
                     /gene_synonym="adhC"
     CDS             complement(42239..44836)
                     /gene="adhE"
                     /locus_tag="ACIZE9_000386"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGC6092281.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(45141..45521)
                     /gene="yajC"
                     /locus_tag="ACIZE9_000387"
     CDS             complement(45141..45521)
                     /gene="yajC"
                     /locus_tag="ACIZE9_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGC6092282.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(45618..46763)
                     /gene="tgt"
                     /locus_tag="ACIZE9_000388"
     CDS             complement(45618..46763)
                     /gene="tgt"
                     /locus_tag="ACIZE9_000388"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGC6092283.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            46981..47679
                     /locus_tag="ACIZE9_000389"
     CDS             46981..47679
                     /locus_tag="ACIZE9_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGC6092284.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(47847..50486)
                     /locus_tag="ACIZE9_000390"
     CDS             complement(47847..50486)
                     /locus_tag="ACIZE9_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGC6092285.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(51105..52136)
                     /gene="queA"
                     /locus_tag="ACIZE9_000391"
     CDS             complement(51105..52136)
                     /gene="queA"
                     /locus_tag="ACIZE9_000391"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGC6092286.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            52329..53504
                     /locus_tag="ACIZE9_000392"
     CDS             52329..53504
                     /locus_tag="ACIZE9_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC6092287.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            53508..54149
                     /locus_tag="ACIZE9_000393"
     CDS             53508..54149
                     /locus_tag="ACIZE9_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092288.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            54146..55063
                     /locus_tag="ACIZE9_000394"
     CDS             54146..55063
                     /locus_tag="ACIZE9_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6092289.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            55060..55731
                     /locus_tag="ACIZE9_000395"
     CDS             55060..55731
                     /locus_tag="ACIZE9_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092290.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(56272..56760)
                     /locus_tag="ACIZE9_000396"
     CDS             complement(56272..56760)
                     /locus_tag="ACIZE9_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HGC6092291.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(56961..57227)
                     /locus_tag="ACIZE9_000397"
     CDS             complement(56961..57227)
                     /locus_tag="ACIZE9_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGC6092292.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(57227..57490)
                     /locus_tag="ACIZE9_000398"
     CDS             complement(57227..57490)
                     /locus_tag="ACIZE9_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGC6092293.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            58011..58151
                     /locus_tag="ACIZE9_000399"
                     /pseudo
     CDS             58011..58151
                     /locus_tag="ACIZE9_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(58293..60116)
                     /locus_tag="ACIZE9_000400"
     CDS             complement(58293..60116)
                     /locus_tag="ACIZE9_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGC6092294.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(60714..63419)
                     /locus_tag="ACIZE9_000401"
     CDS             complement(60714..63419)
                     /locus_tag="ACIZE9_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HGC6092295.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(63725..64672)
                     /locus_tag="ACIZE9_000402"
     CDS             complement(63725..64672)
                     /locus_tag="ACIZE9_000402"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HGC6092296.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            64862..65131
                     /gene="rpsN"
                     /locus_tag="ACIZE9_000403"
     CDS             64862..65131
                     /gene="rpsN"
                     /locus_tag="ACIZE9_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGC6092297.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(65307..65669)
                     /locus_tag="ACIZE9_000404"
     CDS             complement(65307..65669)
                     /locus_tag="ACIZE9_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGC6092298.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(65680..66801)
                     /gene="alr"
                     /locus_tag="ACIZE9_000405"
     CDS             complement(65680..66801)
                     /gene="alr"
                     /locus_tag="ACIZE9_000405"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGC6092299.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(66817..67167)
                     /gene="acpS"
                     /locus_tag="ACIZE9_000406"
     CDS             complement(66817..67167)
                     /gene="acpS"
                     /locus_tag="ACIZE9_000406"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGC6092300.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(67297..68808)
                     /locus_tag="ACIZE9_000407"
     CDS             complement(67297..68808)
                     /locus_tag="ACIZE9_000407"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGC6092301.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(69130..70482)
                     /gene="murF"
                     /locus_tag="ACIZE9_000408"
     CDS             complement(69130..70482)
                     /gene="murF"
                     /locus_tag="ACIZE9_000408"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGC6092302.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(70635..71711)
                     /locus_tag="ACIZE9_000409"
     CDS             complement(70635..71711)
                     /locus_tag="ACIZE9_000409"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGC6092303.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            71907..73652
                     /locus_tag="ACIZE9_000410"
     CDS             71907..73652
                     /locus_tag="ACIZE9_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HGC6092304.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(73932..74369)
                     /locus_tag="ACIZE9_000411"
     CDS             complement(73932..74369)
                     /locus_tag="ACIZE9_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HGC6092305.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(74353..75726)
                     /locus_tag="ACIZE9_000412"
     CDS             complement(74353..75726)
                     /locus_tag="ACIZE9_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092306.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(76048..76536)
                     /locus_tag="ACIZE9_000413"
     CDS             complement(76048..76536)
                     /locus_tag="ACIZE9_000413"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6092307.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(76558..77160)
                     /locus_tag="ACIZE9_000414"
     CDS             complement(76558..77160)
                     /locus_tag="ACIZE9_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HGC6092308.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        22174 a        16458 c        14073 g        24497 t
ORIGIN      
        1 aataccactt aaaccatctg ttacgactaa caaaacctct tctaaaccac ggtcttttag
       61 atcttgaaga atctctttcc aaacataagc agattcagtt ggagctatag taaatcctag
      121 aacctcttta gttccatcca acctgatacc aattactata tagacagctt cttttgatac
      181 ggtttgtctt tttaagggaa tatgagtagc atccataaaa atgactgagt atttagcttc
      241 taaagttctt tctttaaatg ccgaaacatc ttcagacaca attttactca tatttgaaat
      301 agtttgtggt ttgtaataat gaccatacat tttttcgatt agatcagaga tttcggacat
      361 agtaattcct ttttgaacta gctgaataat agtggtttct aaagagtcat tggttctttt
      421 ataagcaggt aaagtttgtt gagaaaagtc tccattccta tctctaggta ttactaaatt
      481 caattcaccg tactctgttt taaaagagcg cgaataattc ccattacggg aattacctga
      541 attaaatcca gctctatcat acttttcata gtcaagaaat accgttaatt cagcttgtaa
      601 taaagcgtta atagccaatt ctaggtgacg acgaaacaaa tcatccaaat cacctttatt
      661 gattagtatt tccataattt ctgtagtaaa atcgttcata tggaagtcct cttttctgtg
      721 aatgtgttgt ggtaactcta ttctacagaa gggacttcct tttttctatt tacacaaaat
      781 attttacact ctcttcaacg atattcttgt aagtaattat gccccaacta ggatttgtgg
      841 gttcatttcc atctggagtt aaaaaaacaa aaattttttt atagttagaa taattgcgtt
      901 ctatatatat ttggtattta ttaagttgcc ctccagactc cgaagacaga attttatttt
      961 cgatgcacac cactatttta tttttttccg ataccaataa aatatcaata ttcttatttt
     1021 ctctgtaaac aattaaatct tcatagctat taagtaaagc atcaaaataa ttgatagcag
     1081 ctttggtatc atcattagaa tctatatacc ttttcaaaaa cattttaaaa aactcatcag
     1141 ataaattgtg ggtttcattt ggagcaaaca aaaaagctaa aaaattacta tgtcttattt
     1201 catttttaga tagcttaagt atctgaaata tatttgtttt cccagtccat ttagatagtt
     1261 ttcttcaata tcatccatat cctctaatag attttttaaa cacttttttt catctatcat
     1321 gttttttctc cttgccatta ttctaactaa aattttacgt atttgtttct atgtctacat
     1381 tatcttttta acagtatcta tttttctttt gcaacttact tggctaccaa agcaaataaa
     1441 aaagttattt ataaatttct ccctaccact acctattgct attatttaaa atagggataa
     1501 ttttttctct taaaaaatat cattatttgt ggtatggagc ccccgcattg atccggaagg
     1561 cacggtagat ttgctcgaca aggatcagac gcatcaattg atgtggatac gtcatttttc
     1621 caaaagagat ctgagcattg cttcttttca tgacggcttc gctgagtcct aaagagccgc
     1681 cgataacaaa aacaaggtgg ctttttcctt ggatacctaa ttggtcgatt tgtttagcaa
     1741 aagattcact tgtaggattt ttcccttcaa ttgctaaggc atagacgtat tcttgttctt
     1801 tgattttcgc taagatccgt tccccttctt tttcttttac ttgtctcatt tgcgcttcgc
     1861 ttaaattctc cggggctttt tcgtcaggaa cttcgatcaa ttcgattttt gcataggcat
     1921 tcagccgttt gacatactca ttgatacctt ggatcaggta tttttctttt aattttccta
     1981 ctgagataat tttgatattc atgttttctc tcctttggtc ttcatgctca ctttgtttat
     2041 tataatcaat tttttcgtct atatgtttat tttggctatt tttgttaaaa agatttcccc
     2101 aacagttatg cacaacatcc acaggtttat ccacagaaaa cagtgttatt ttaccttatt
     2161 tcatcacatt cattaggcaa acatacgttt tataagaatt tatccacttt atacacaggc
     2221 tgtggatatg ttttatccct tatttttcca atcctatccg cgtagtttta cacagtatct
     2281 gtggaaaaag aaaatcaaat attttcatct gaaaacaatg atttttccta aagtttttca
     2341 taaaaagttc acagtctcaa agtagactaa agtcaacaaa taagactata ctaacagtag
     2401 ataaatgaat gtaattggag gaggaacaca tggatagaaa aaatgtgaca ccaaagatga
     2461 aaaaaagtaa aaataatagc ctctggcgta agttaggtct ggggcttgtt ggagggatcg
     2521 ttggaggact actgacagct ggcatttttt atgcagcgat gggcactggc aacaatagtt
     2581 ctactgctac aagcggcaat cagaattctg ccggtgaaac agttgtggaa aatgtcaaag
     2641 tcaatgtaga ttctgatatc accaaagcgg tagataaagt tcaagacgct gtcgtttctg
     2701 ttatcaactt acaaagtcaa aaccaatcaa gcggttttgg cggactattc gggcagcaag
     2761 aagaaagtag cagctcagat gatagtaatt tggaagctta tagtgaagga agcggcgtga
     2821 tctacaaaaa agacgggaat actgcttatg tagtcacgaa taatcacgta gtagatggcc
     2881 agcaaggtct tgaagtcttg atgaaagacg gtacgaaggt aaaagctgaa ttagttggaa
     2941 cagatgctta ttcagattta gcggtgttga agatcaattc agacaaagtc gaaacagttg
     3001 cctcttttgg tgactcaagt gctctgaagg ttggtgagcc tgcgattgcg attggttccc
     3061 cactaggatc tgaatatgca aattctgtca cttcaggaat catttcttcc ttgaaccgac
     3121 aagtgacaag tacgaatgaa tcgaacgaaa cagtcaatat caatgcgatc caaacagatg
     3181 cagcaatcaa ccctggaaat tctggtggtc ctttagttaa tatcgaagga caagttatcg
     3241 gtatcaactc aagtaagatc gcaagtactt ctgaatctac ttctaatgta agcgtagaag
     3301 gaatgggatt tgctattcca agtaacgatg tagtgaatat catcaatcaa ctggaaaaag
     3361 acggaaaagt gacacgtcca gctctaggta tcacaatggt cgacttatct gccgtttcta
     3421 ctcagcaaca agaacaaatc ttgaagattc cttcatctgt aactaacggt gtcatcgtga
     3481 caaatgtcca aacagctaca ccggctgaaa aagctggatt gaaacaatac gacgtcatta
     3541 ctaagatcga tgacaaagaa gtttcttctg gtgtagaact tcaatctgct ttgtataaga
     3601 aaaaagtggg agattctgtc aaaatcactt actatgaagg ctcgaaagaa aaaacaacta
     3661 ctgttgaatt gacgatcgat caatcggcat taaaacaaaa tcaaaatagt gaaaattaat
     3721 aaaaaagagg ttgtgacaaa gacttgtcac aacctcttta ttttggaaat gcttctccga
     3781 ctacggcatc ctcaggcaat actaagattc ctttttttgc tggagcattt ggcaaatgca
     3841 attcacgagc ggaacagatc attccatagc tatctacccc tcgcaaagtt cctggccaga
     3901 tcatcattcc atctggcatc atagctcctg gttttgcaac gacaactttt tgtccagctt
     3961 cgatattggg tgcaccgcaa acgatttgca atactgtacc attgtctact tctgtctcag
     4021 taatcgataa atggtcagaa tcaggatgtg ggacgcatgt ttttacgtac ccgacaacga
     4081 tcttcggttc atgatcagct tcaagctgtt cttcgaatcc tgcttctttg atcaatcgat
     4141 tcaatttcgc taattcctca tctgttaagc ttacttggcc gttcccttcg attgttagat
     4201 gatcggagat atggaaaaag ttccaagcaa caacttgacc ttgttcatct ttgatccgag
     4261 caacattcca tttgcgttca acagtgtttt ctgttccttt atcgtcggct ataataacca
     4321 tcaaggtgtc tccgacgtgt gctttgttat aagcaaaaat catgttcttt cctccattat
     4381 cctttgctga gatttatctt aacaaaaaat tgcattcact gcatgaaatt tttttcatgc
     4441 tttatttccg aagaagcctc ttctggaaca ccatttattc gtaacaaggg actgtgacaa
     4501 gacttttgtc acagtccctt tactgtttta gttaattgat taaaaaggtc gtacaagttc
     4561 cacttgctta attacttggc tgttcttctt cgtcagaaac gatcaagaca tcacaaggtg
     4621 aatgacgtat cacgtagctg gctacacttc ctgtcataaa gcgttcgact gcatttagac
     4681 ctgactgccc aaccatgatt agatcgatct catatttttt tggcaatttg actgccatgg
     4741 attcacgaac agaaccatat gcaataattc cttctatatt tgtgtaatca acagatttcc
     4801 catattcttt acattcttcg atcatttcct tggctgtttc agtttgctga tcgactagat
     4861 tttgatcaat aggtgcatag cccataaagt tataaaattg ctgatcgatt acgtttgcta
     4921 catatacttt cccattatta cggcgagcca cttctaccgc ttttttgaaa gcagcaagtg
     4981 cttgttcact accgtcgata cctactaaaa tattcttata ttcttgattc atcttgaccc
     5041 ctcctaacag atgtcagcct tttgttacac tttctaggaa cgattcgatt tcctgttttg
     5101 ttttacgatc tttattcact agacgaccta attcttttcc gtcttggatc acgacaaaac
     5161 ttgggatacc aaaaatgttc cattcagcgg ctacatctat gtacttgtca cggtctactt
     5221 caataaattg ccaatcagaa aagtcatttt caatttcagg catttgcggt ttgataaaac
     5281 ggcagtctcc gcaccagccg gcagtaaaga aaaatacact ctttccagtt tctacgtagc
     5341 ctgctaattc ttctaaacta tttgggataa tcattctttg tcctctactt tctgtttatg
     5401 tatttttcaa ttaaattata cacctttctt tcgaactaac aaacattgat cctcttttta
     5461 taaaaaaaat ctggcaaaaa gcaatctttt gccagatttt atagtttcac tatcgcatta
     5521 ttttccgtat acgatcgtat ttactgttga tttatccaaa cctttcagtg tttgaatcaa
     5581 catttctcgt gcagcttcaa aatcgcgaat actgaacatc gtttgatgcg tatggatata
     5641 acgtcccact acgccaatca ctgtacttgg gattccttcg ttttgtgtat gagcagcacc
     5701 tgcatctgta ccgccttttg aaacaaagta ttgataaggg atattgtttg tttcagcgat
     5761 atccagcaag tactcgcgca aacgaggaag catgatcaaa cctggatctt ggatacgcat
     5821 caatgtacct tctcctaaat gtccgaatgt gccatttttc gtcactgtat catctgctgc
     5881 agagcagtct actgcaaaga acagatctgg cttgaattta ttgacagaag ctttagaacc
     5941 acgcaagcct acttcttcct ggacattcgc gcctgcaatc aatgtatgac ctaatgtttc
     6001 attttgcaac gcttctaaag cttctaatac cattgtacag ccatagcggt tgtcccatga
     6061 tttactgata atattctttc cgttggctgt tttgatcgtt tcagcgtaag gaacgattgt
     6121 gtctcctgga aggacaccgt aactcattgc ctcttctctt gattcaaacc cagcatcgaa
     6181 caaaatatcg gttacttcta ctgatttttg tccgcttgtt cctcgcaata aatgtggggg
     6241 aacggaagaa gaaatacatg gataattctt accagtagag gttttaagtg taaaacgctg
     6301 agcagaaaca acgtaaggat tccagccgcc tagaggtacg actttaaaaa gcccgttttc
     6361 ttggatttgt gtcagcatga atccgacttc atccatatgt gctgcgacca ttacacgggg
     6421 tgcatccgct tcttcatgat ggcgcagacc aaaaatgccg cccaaaccat ctaactgtaa
     6481 ctcatctacc agcggttcca tatgactttc catataagcg cgaacatctt gttcaaaacc
     6541 gcttgttcct tgtaattctg ttaactcttt gattcgttga aatgtttttt cttccatatg
     6601 ctattcgtct aaatttcaga ctaaactcct ctcagactta tattgatctg cggataaaat
     6661 atgatttttt ctgcagaccg atcgtattta ttatagctta ttttttctgg tagcggttat
     6721 ttatttcaaa gaaaatatga gagtgtggta aaataagcac aaggagtaac aagtgagaag
     6781 aaggaggtat gtccacatgt atgaagaaag cgaactaagc tattttaaag gcgggttagc
     6841 agttggaatc ggtctaggat tattgagcgg ggtagcttca acgatttggt atcatcgcaa
     6901 aaaagtattg tcagcagacc aagtacttga aaatatcaag tcatcttttc taaaagaagg
     6961 tgcaatcgaa ggttcttgga tctcttttga aaaggaacct attaggaaat tcgccgttcg
     7021 gtcgagtgct tatcggggag gtctttctcg aatagaagat ggcgaaactg tttattatga
     7081 atttttagca gatgctcata caggaaccgt attagaaatt tcaagaaaaa aaggtgcaac
     7141 agattaatac gtcaaaaaag tgagagaacg aatacgcacc cactattcaa aagagaggta
     7201 tcatgtcctt cttttgtagt gggtggtttt ttagatagag ctttccaaac atatattcca
     7261 gtattttctt tttaaataaa tgatatttag cgggaaaaac tagcatttcc tttgattatg
     7321 aggtattttt aatttagctt ttgttttcta tagttaagga gagtgaaaaa tggaacaaca
     7381 agaaaaaatt gctgttctga ttccttgtta caatgaggaa gcaacaattt caacagtcat
     7441 tgcagacttt aaacgagaat taccagaagc agatatttat gtctatgata ataattcgac
     7501 cgatcgaaca tacgaattgg ccgttcaagg tggagcaatc gtaaaaaaag aacctcgtca
     7561 aggaaaagga aatgtgatcc gccaaatgtt ctttgatatc gatgccgact attatttaat
     7621 ggtagatggc gatgatactt atcctgcaga agctgtacat ggtttgctcg agaaattacg
     7681 ttctggtgaa gcagatatgg tcattggtga tcgcctatca aatggaacct actttgatga
     7741 gaataagaga cctttccacg attttggaaa taaccttgtt agaaatacaa ttactagaat
     7801 gtataaaaca aaaattcttg atgtcatgac cggctatcga ggattcaatc gtatctttgt
     7861 caaaagtttt cctattatga gttctggttt tcaaatcgaa acggaattga cgatccatgc
     7921 tttagataaa aaattcaagt tcgttgaaat cccaatcgat tatcgtgatc gtcctgaagg
     7981 cagcgaatca aaattgaata cattctctga cggattcaaa gtgatcatga tgattattaa
     8041 aatgtttaaa gattataagc ctttgctttt ctttgggatt tggaccatct tcttcttttt
     8101 atttggattg gtcacgggga ttcctgtgat tcgcgaatat atgctgacaa gctttattac
     8161 acgcatccct tctgcgattt taagtactgg attgatgact ttagcacttc tttcattagt
     8221 aacagggttg attttggata cagtcgtcac gaacgctaag aaagaatatg aattgaatct
     8281 atatcatgtt tatcatgaat accacagtag aaagtaaaaa aaggatcaag actgcaaaaa
     8341 taatttgcaa ttcttgatcc tctttttaat taattatttc gccaaacgat agatggcatc
     8401 tgcatagatt gctgttgctc tgaacaagtc atcaagactc ataaattcgt ttgcttgatg
     8461 cattgtatca gtatatcctg ggaacatcgc tccataagca acgccacgtt tcaacaaacg
     8521 tccgtaagtt ccgccaccga tgatttgttc gtagcctttt tctccagtgt ggtcttcata
     8581 gacttgcaat aatgtagcca ccaatggatc atccattggt acgtaatgtg gttccattac
     8641 gcgagcacct cgagtaactg ttgcgccttc ttgccccact gtttgttcga tgtcactttg
     8701 caatccgtct actgttacac cttttggaaa acggaaattc atattgatga agttcgcttc
     8761 ctctgtacca ttttcttcaa aagcaaatag tccagcattc attgtcaatt tgcccatttt
     8821 ttcatcttca taagcgactc ctagtttttc tccataaaaa tcttcatgga cataagcagc
     8881 tgctacatgg ataaattgtt tagcagatcc taggaattca tagttatcta agaacaatgc
     8941 caagaaagaa cctgcattga taccagattg tgggcttgca ccatgtgcgc ctttaccaac
     9001 taattcgatt tttacatacg tattgtccgc ttcaatcgtt ccgcttactg gatttgcttc
     9061 gatgaattgg taaaatgctt cttccatcgc gatagctgca tctgcacttg gtacttgaag
     9121 tgctgcagtt gctgttcctg gcaccatatt ttcgcgaagt ccggaaacaa aagatttcaa
     9181 gacataatct cctgcattgt cgcctttgaa gcgtaaagct aaagaaacat ttcctttttc
     9241 accattgatg attgggaatt cagcatctgg tgagaaacca aaatctggtt cttcttcatg
     9301 ttcgaaataa taagccatat cgccccagcc gctttcttca tcgctgccga ctacgaagcg
     9361 aacttttttt gatagtttca agtcaagttc tttaatgatc ttcatcgcat agtaagctgc
     9421 catacttgga cctttgtcat cgcttgatcc gcgtgcaaag atctttccat ccttgattac
     9481 tggttcataa ggatctgtgt cccagccatc tcctgcagga acgacatcca tgtgtccaaa
     9541 tatccctagc gtttcgtctc cttcgccaag atcaatatgc cctgcatagt tatcgacatt
     9601 ttttacttta aatccatcac gttcgccata agctaacata tgtttcaatg cgtcgcgagg
     9661 tccaggtcca aatggtgcat ctggtgttac ttttgagtca tcgcgctcgc tgttgacacg
     9721 taaaagattt ttcaagtctt caagcaagtc ttctttacgt gcttctactt ctttttgcca
     9781 atcaattgtc ataaagttaa tcctccactt atttaagtct tcgtgttcat gataccacaa
     9841 attacagaaa aaaatagttc aaaaaatctg acaattcctt ttcttatctg tttttctcta
     9901 aaaaaaatat acgctataat gagtaaaagg aggtttttag atgctgataa acgaacaact
     9961 agtgaaaaga gtcatcacac ctcgtccaaa aatttcacat aaaggaacat ttggacgtat
    10021 cgttttgatt ggcggcaatg aacaatatgg cggagcaatc attatgagtg ctttagctgc
    10081 cgtacacagc ggagcgggtc tcacgactgt agtaactgat gaaaaaaatc ggagtgctct
    10141 tcacagtcat ctgccagaag caatgattgt agtttggacg gatactgacc agtttctttc
    10201 cgtaataaag caagcagatg tactcttgat tggtcccgga ttgggtactt cttctaagag
    10261 tttggaacgt ttcaaacaag tactagaaaa ccaatcaaaa gaacaatggc tggtgattga
    10321 tggctctgct ttaagtttac ttgctgctaa tcatcttttg ctaccctatc ccgaacaaac
    10381 tgtacttaca cctcatcaaa tggagtggca acggttgagt tctctaccga tacaagaaca
    10441 acgggataaa gaaaacaaaa agaagcaaca ggaaatcggt gctgtgctcg ttttgaaaag
    10501 tcatgagaca aaaatttatg gtcaccagca cttctacacc aatcctttag gttctgctgc
    10561 tatggcaacg ggcggcatgg gtgacacttt agctgggatg atcacaggat ttttagccca
    10621 gtttcctcaa aatgaccaaa cgattgcagc agctatttat cttcatagtt tcattggaga
    10681 ccagctggca aaagaacaat atattgtttt gccgacacaa atcagcgaag cacttccgaa
    10741 atggatgaat tatttttgta aaaaatcaat ggaaaacgag gcatgagtca tggagaaatt
    10801 tacaggttat gtgcgagaac ctttttatta tgaaacagat caaatgggga ttattcatca
    10861 cagcaattat atccgctggt ttgaagaggc tcgggtagcc ttattggtac atctagggtt
    10921 tccctataaa aaaatcgaag aatctgggat catcatcccc gttctggaag taaattgcag
    10981 ctataaagaa atgatccatt acggagaaaa agtgagcatc catccaacta tccaaaagta
    11041 tacggggaca cggttggatt ttagctacga aattgtggga actgaagaca aaaaattaaa
    11101 aactactggc agtagtaaac actgtttttt actttctgat tcgcaacgat tagtgaagct
    11161 gagcaaagtc aatccggagt tagatcagtt attccaagcg tacgcttctt tggatgatgt
    11221 aaattcttaa taaagaccgt ctaagcattt ttcttgtatt gtgtcgagta gttcgtataa
    11281 tgaaaagaaa aaagcaggtg atccccatgt atgtcgttaa agtaatgcac ggttacatcg
    11341 ataaaactgg ctgtcgcact cgggaaaaaa acttagacaa tctgctcatt ttcaaagaca
    11401 aaaaagaatc cgaagctttt gctaaaagaa tcggcggtcg tgtcaaaccg atccaagagg
    11461 tacgaccaga ttgattcaat atttttcttt tcgaggctct aataggcatg cctatcaggg
    11521 ctttttttgc agactgtgtt tttatgccca cacgatttgt aagcgattta tgttataata
    11581 gattatatct gcatagaaag gaaggttaaa tggttatcaa taatttgcaa cagcaagctt
    11641 atgaatctat acgtaaacaa atcatttatt ccgagttagc acctggaagt aaaatctccg
    11701 ataaagtgtt agaagaacaa ctagctatcg ggcgtacacc gattcgagaa gcactgatcc
    11761 aactgcgcaa tcaagagctt gtaaaaacca ttccacagtc cggcacttat gtttcaaaaa
    11821 tcgatatccg atctgcttca ttagcccgtt atacgcggga aaagttggaa aaaccgatcc
    11881 tgcaagaatg cagtgcgaaa atgaccaagc aagatcaagc taaactagaa aaaatactag
    11941 aacaaaccga tcaggcagta atcgctcaaa ataaaaaagc tttttttgat ttggatactg
    12001 attttcaccg aacttgttat gaaattgctg gaaaacgaga aatttgggat tggctagaaa
    12061 gttatagtac gcgtttcaga tggttacgtt tgacgatttc agaattagac tggggtcgag
    12121 tattagatga acatcagaca atgcttcaat caatgattga tcataacttt gatgaagtcg
    12181 gatttctttg cacgatgcat ttacatatga ttatcgagga gcaagaatac gtgattcata
    12241 attaccccga ttattttgaa gatattcagg acagacccat caaataagag gttttggaat
    12301 cagcgttttg acctgagtat tagagaaaga aacggcaaaa tagttcctca tattttgccg
    12361 ttttttttga gctaataccg agggtcagct gattgcacac cgtttattga gaggttgtga
    12421 aaaagctgcc ctgcatcaag taataagaac agccaagtaa aaatagcttc ttatgttttt
    12481 aacttggctg gacttattac cgcagatgca agcttttgaa caccgttttc caagaggtcg
    12541 tgagcctgcc gttcatctcc gagtcacaag gaacaatttc aaaaaacagc ttctcatgtt
    12601 tgttgaatat tttgacttgt gaccgaggag ttgacaggag aacatcgttt attcggaaaa
    12661 aaaggactgt gacacgactt ttgtcacagt ctctttattt gtaatctaaa tcatactccg
    12721 tacatctttt ttctattttt tttatttctt ctaagatccc ttggctacga atttcattat
    12781 atggccaaag taagactgcc tctaatacat aaggcgaaaa atcgctttga ttcatctctt
    12841 ttgaaaaact catcgctgct atctcgctca atgcacgaat gtttgattga tgtgtataaa
    12901 aaggcaaccg ccacagcaca attttttcgc tttgcgtata aattccctta acagaagctt
    12961 cgatgtggtg aaatagttca tgtccaataa tcaaagcttg cgctgtttct ttagagatcg
    13021 aagctagtcc tgaacatttt aatttttcta acggctccgt catcaatcga atcccttcat
    13081 cttctgcata agttgcaaaa gtgattcgtt cgtttatttg ctctgattca caggaaacga
    13141 ttggaacagc catttgttca caaatttctc ctacatcggc aaaagggtac ttttttttga
    13201 tgctacatgc cgtttcgata ccacaatcga ttgattgttg tataagaatt ttctgcttgg
    13261 acaaaggaat ctttttccaa aataaatctc gccgaaactg gtagaatccc caaatttctt
    13321 cggggatctg ttgtaattcg tttagtaact cttctaactt atgtttgttt gatatttccg
    13381 gcaacgacga tcacttcttc ctccggttcc atagtagata cttccagatc catcaaaagc
    13441 tgtagttgtt ccagatccgt cgctgtaaaa tcagagactc ttgctcctaa gcagagataa
    13501 aattctggtc gggcaatcaa ttcagtttga taaactgcca tatcttccca aagttgttcg
    13561 acagctgtca tataattggc tgcagttgtt ttcatacatg aagcatgtcc acgttggacc
    13621 ttgataaatc ctttttgatc gatgatccga agacttccag cattttttga acgattctgt
    13681 tcgccgcata cataaaagaa aggtgtattt tccaataagc aaacttcatt tttatttaat
    13741 cgcatatcct ctgcagcaag ctctagtgct tcttctgttg tgatctcctt ggttagatcg
    13801 gttgctttca cttccgtaga accagtagcg atagccgtta cttttgaagt ctgtggatcg
    13861 atttctacgt ggacttcgat cgattctggt gtagcgcctg attcaatcgc tttattcatc
    13921 gcttcatttt tcaacgatcg tatatcttct ttacttggcg aagggatgat acgttctaca
    13981 acatctcgga ccattgcaag tgctacacca atagaagaaa tcacttcggc gttttcagga
    14041 atcgaatatt tcacacccat tttattacta aagtaagtaa tcaatgaggc agcgccgccc
    14101 cctacaccta caagagaaat ctgatctttc tccaagtgat acttgtctgc caattctaaa
    14161 atcaccggtt caatcttagc ataggatttt tccatgatct gttctgcgat gtcttcaacc
    14221 gtcgtatgac aataatcagc taatgcttgg atggcttttc gtgcagatgg gacatttcca
    14281 taagaaaaat gttcttcttg cactaatcca aggacattgg ctgcacatgt atttgtaata
    14341 gtcacttctt ctccgtcttc catcactacc ttgacgtaat cagcagggtc tccttcttta
    14401 ggagagaaaa attcaacctt aggacctttg attttttctg tctccgtaaa tactgcataa
    14461 tctagaccgg caatatgtgc agaacgtgga ccgacatcga tgattcctga ctgattagcc
    14521 cgtaccatcg aaccgcctgc cacacctaga acccgaacat ctaatgaaga gatatatgtt
    14581 gggtggccac ctacaattga ataatcgatt gctggacgtc catttttaat gaccccgata
    14641 ttggttgttg ttccgcctac ttcaaaataa acaccattag acgctctcaa gtacatcaaa
    14701 gagcccatga ctgatgctgc tggaccggaa agcatggtta aaacaggtcg ttttttcatt
    14761 tcattgattt ccattactcc gccgtctccg cgcataatca tcaaagaaac attgacccct
    14821 gcttctcgta cggaatcttc tgtagaggtt gccgtatcta gcatttttgg taaaatagat
    14881 gcattgattg ctgctgtccg agttcttctt gtcaatccat ataattttgt gatgtcagaa
    14941 gccatcgttg tagggatcga ttttaccgat gctgcttcat aaacaactcg ttctggttcc
    15001 ccattatcta ctccaaatgc catagaagaa accaagacct ccgctctttc tctttctaaa
    15061 gaagaaatcg tttctgaaac acggtctaca tttaagtgtt tgacaggtaa gaatgcattg
    15121 acaatctcta tttttttctt attccctaaa tcgatatcgt tcaatctagt ttgtcgtttt
    15181 gctaaaaaac cttctaatcc accttttgcc atcccgatta cgccgacttt tgctacgtct
    15241 ccttcaatca gtgcattagt cgcttgtgtg gtagaatgtg caacaaacac aacatcttct
    15301 ggactgatat tattttccag caaacaattt tgaaaagact gaacgacacc tgcggctact
    15361 ccacggacat catcgtgggt tgttttcact gaagattttc cgatgatttc gtgcgtcgca
    15421 ttatcgattg cgactgcttt cgtatgtgta ccgccaacat caattcccat tcgcacaaaa
    15481 cgtttcattt tcttttcctc cattcatcta atcgttttta tcgacgtttt gtttactagg
    15541 cgttcccgta caataagaac gtgatcaggc ataagatcgc tccgatgatc caaccagttg
    15601 ggatggattt cttcatatat tctcgagaag ttacttttgt ataacctaat ccccaagcaa
    15661 cccaagattg tgtaatatct aaatgctgag gagcaatcgt tgtgattgca aataacggga
    15721 acaaaaaggc tggcgacatc gttggattaa cagctaatac gacagctaaa atagctgagc
    15781 ctgaaccgac tagattcatt ggaccgcgga aaaatcctag tggtgtcaat atagcaaata
    15841 cgattgccaa gactaatggt gattgcggta tccaatctcc aaaaatagct gaaaaataag
    15901 gagaagcata cgcagctgaa ttattgaaca tcgctaaggt catcaagaaa ccaaccattg
    15961 gcgcaacatc tactgcgcca tctgtaaata atttcgcaaa ctgacgacag atttctttat
    16021 aacctccgcg caattttcca gtaaacagca atgcccagat acctgctaga ataaaaccta
    16081 agatgattgg aagatctaaa agaacgaccc ctaaaactgg taataatacg gctaaccatg
    16141 agatcattgg tgcgtcgcca ccttcagctg gtacgtttgc tgccattgca tagcgtttct
    16201 ttttgttcat tgatatatta gcgaccgtta gtaccacaac taagcttaca atcatcccaa
    16261 tcataccaat ttggaaatag tcattataag tatagctttc agccgctgga ttgaaaccag
    16321 cataaatcgt ttgatattgt ttgaaattga cgatattagc aaagattcca gccataatcg
    16381 agcccataaa tgagaacagt gcaaccggta ctgaaatacc taatgacatc aagattggca
    16441 acacaataac tgcaatagaa atcactggtc cgattcctgt catcgacatg aatataacag
    16501 cggttacaat acatagtaag ctcatcgtga ttcttggctt gtcccctcca agttcaacta
    16561 cctttcgaat cagggtagct gcgattccgc tatctactag aacacgcccg aaaaaggcac
    16621 caaagaagac atttaccaag atcgatttgg cgtactcagc tggccccgtc gtatagatat
    16681 gcgtcaacac atcaattact ccttgccctt ccatcgccgg gtttggtgaa aacgtgtttc
    16741 cgactagcgc taatcccatc catacagtag ccatgatggc aaagccgacc atcaagttgt
    16801 agccttttac acagtaccag accatgaaaa agaatgagat aactaacaaa ataccaataa
    16861 taatatcact catgttattc ctccgtccat tttgtttttc tgataagcaa actaatatat
    16921 cagtcaaact cattctaact tatgtagtta gcgctttcat taaagggtga ccataaatgt
    16981 tcagttttca attaaaaaac cttaattatg ctattttaga cttatacgtt attgtcctgt
    17041 ttcatttgat ggaggattgt aaataaaaaa agaggaaaga acataacttt tcgttatctt
    17101 ctttcctctt tataattgtt tagcttattt agccaaagct tcttttgctt ggtcagccaa
    17161 tgcagtaaat gctgctgcat cgttaacagc caagtcagct aacattttac ggttgatgtc
    17221 gatttcagca actttcaaac cgtgcattaa ttttgagtag ctcaagccat tcatacgagc
    17281 tgctgcgttg atacgagcaa tccacaattt acggaagtcg cgtttctttt gacgacgatc
    17341 gcgatatgcg tagttgtatg aattcattac ttgttctttt gctgttttaa ataaagtgtg
    17401 ttttgaaccg tagtaacctt ttgctaattt tagcactctt ttacgacgtt tacgagttac
    17461 tgttccacct ttaacacgtg ccatgtataa ttcctcctaa taaaaataaa tcttcagatt
    17521 ctgttatttg tacttcttat ttcatttttg ctagttgttg gcgaatacgt ttgaagtcgc
    17581 cactagaaac catgcttgct ttacgcaatt gacggcgttg tttttttgtt ttgccgtgga
    17641 aacggtgact tgtaaacgcg cggaagcgtt tcaatccgcc tttaccagta cgtttgaaac
    17701 gttttgctga tccgcggtgt gttttttgtt ttggcatgac tatatttcct cctcaaaatc
    17761 tttcgttatc cgactatcgg ctgtccaaca gccagttagt cattcaaatt acttactgtc
    17821 gtttttcggt gccagcgtca agaacatgct gcgtccgtcc attttcgctt tttgttccac
    17881 tgttgcaata tccgcagttt cttcagctaa gcgattcaag actttttgac caatttcttt
    17941 atgggtaatg gcacggcctt tgaaacggat agaagctttc actttatcgc ccttttccaa
    18001 gaacttacgt gcattacgaa gttttgtatt gaagtcattc aagtcgatcg taggacttaa
    18061 gcgaacttct tttacattga tcactttttg ttttttacgc gcttcgcggt ctttcttttg
    18121 ttgttcgaaa cggtatttac cgtagtccat gattcgcgca actggtggtt tcgcaccagg
    18181 ggcaactaac acaagatcca agtttgcttg ttctgcaata ttcaatgctt ctgcttttgt
    18241 cttaactcct aattgctcac catctgaacc gatcaatcgt aactctcgtg cacgaatgcc
    18301 gtcgttaacc atcatatcct ttgctatggt cattcacctc caaatattat gagagaaaga
    18361 aaagcttacc gaataaacgg caataaaaaa acgagttctc ttacagaacc cgcgcgtact
    18421 tcacctaata gaaccagtga aaactatcta gcccagtgac attatcaact aaggcgagaa
    18481 gcgggtgctt ctgcttttat ttctcaacca tcatagtata gcaaaaacta atctttttgt
    18541 caatgttttt catacagttt gtcttccttt tctgaaaatg attagattag cagactttct
    18601 agcagtgatt cccgcttctt tgctatacta aagaaaaacg aggtgaaccc acatgaaaaa
    18661 aatcgaacct attccacctt ctcttcctct tcttacaaag ggagagtttt atttagaaga
    18721 tgaggagatc ttctctggtc ttctgatcaa cgggggtgac caaagctatc tcgatgccaa
    18781 aaatatggta ttaagagaga gtcatatcca aaaacttacg atgcaaaaaa cagttttacg
    18841 tcattttgaa tgcagtaatg tcatttttga aaaatgtgat ttttccaatc tggagtggat
    18901 tggtggcagt ttccaccaag tcgtgtttca tcaatgtaaa ttaacaggta cgaattttgc
    18961 cgaaagttat cttcgagact gtactttcac tgattgtatt gcttcgatgg cttcctttag
    19021 tagtacaaac ttgaaagctg tctccttcga tcattgtcaa ttagaagaca gcgaatttta
    19081 tgaggtcact tggaaaaacc tttttttgtc tgacaatcag ttgaccggtt cgaactggtt
    19141 tcgaacttct ctgaagggat tagactttac gactaatttc ttcacagcaa tcgctttatc
    19201 tcaagattct ttggcgggac taatcgtcaa ccaagagcaa gcacttgtga tcgcccaagc
    19261 ccttggtttg cagatcaaag actagatcaa cgaatccgcc gccacagtgc aataagcatc
    19321 caaatagata agaccaaact gatgatcaag gcgattcccc atccgaaaac ggaatgggta
    19381 aagggtaact ggagattcat tccgaagaat cctgtcacaa tagttggaac ggtcaagatc
    19441 agcgaccaga ccgtcaaaaa tttcatcgtg tcattcaagt tgttattcag caaattatta
    19501 taagtgccag agagctggtc taaaatctgc gaagctaagt tcgtcatttc aactgcttgt
    19561 cgtgcttcga tcagcgcatc gtccaactct tctttttcct tttctgacaa cttgcgataa
    19621 atagccaatg ccttgatttg ttctaaaagt actacatttt gttttgttcc tgtaactaag
    19681 taaaccaaac cgatctctaa atctgaaagt tgcagcagat tcttgttcgt tgttttttct
    19741 cttaatttca gattaagccg ctgacgttca ctattcactt cctcgattaa aggaaaaaag
    19801 gaatcagaaa tcaaaaacaa tgtacgaaac aataaactgt atacactcat gtctggcatt
    19861 cgttccaaaa gcgatcgaat tagtcgaatc acgtactcgg tattcggcgt ggtaaatgta
    19921 aacaaaccgt cttcttttaa aataaaagcg ataggactag tttcataatg attatcgact
    19981 ttttgctggt gcggaacatt tgatacaagc agtaacgctt catcaaaaga atcgtactct
    20041 acgcgcgccc gttcattttt atctagagaa taagtcagca tctcgtcact aatgccatat
    20101 tcttctttta agtttttaac agctagcaca tcgttttgct gtacattgat ccaaaaatta
    20161 cggtcttgat taaaatagtg tttttcccgc atactctatc ctcctgacat ttgtttccag
    20221 tataaagaaa aaagtcgctc aaataaaggt ttacccttta tttgagcaac tgtaaatcaa
    20281 atggctactt tggtttggcg aatctctgct aatttttctt cgatcatttt caagacttct
    20341 tcttttgctt gaggatcttc cacaaaatta tagcggtctc catcgatttg gatttttgga
    20401 ctttctttgt attcttcata ccattgatcg taacgtctgt tcaattcttt gtaataatcg
    20461 tatagacttg gatcaaagga caattgttca tacgaacgac cacgtttttc gatacgctcc
    20521 aacatcgtat caaaagatac acgaatatga actaataaat ccggatgttt tttatgggca
    20581 gcatagggaa gttcttccat catgttttcc agcagttcat catacacacg aacttctgtt
    20641 tctgttgctc ttcctagatc tgcatttaga tggaaaagca gtgaatcttc ataaatcgaa
    20701 cggtccaata cattattgtc atctttcatt gcttgtttga tgcttgcaaa acgtttattc
    20761 aaaaaataaa tttgcagcaa aaaagcatac tgttcagggt ttgcataaaa taagggcaag
    20821 acttcattat catcaatcga ttcataaaat gcctgactat caaagtgttc agccatcatt
    20881 tctgttaaac ttgattttcc ggcaccaatt gtacctgcta aaacgatcac gctcatttac
    20941 ctccagctca cttcatcact aaatattgtg tttaactcca acctttttaa atataccccc
    21001 aatatctagt agtgtcaatt gtattttttt ctagtcaaag aagaaaaaaa gtcaaaaaat
    21061 tcttaagaaa aaagtgtttt ttctttagaa aacgtattct tagttttact tctgagatgg
    21121 ttttagtaaa ataaaggagg aatgtttttt gagaccctta gtggacaaaa aaattcgtga
    21181 agcagcgcaa ctcgttttgg gcgctttatt ttttgcttaa aaatcacttt tacgtgagaa
    21241 ggagttagat tatggcaaac tatggccaag gagaatcaag cggaaagatc atattgatgg
    21301 gcgagcacgc ggttgtttat ggagaaccag cgattgcctt tcctttctat gcaacaaaag
    21361 tcaccgcatt ccttgaagag ctggatgcaa tggacgatca actggtttct tcctactatt
    21421 caggaaattt agccgaagct cctcatgcat taaaaaatat caaaaaatta ttcattcact
    21481 taaaaaaaca gcatgacatc caaaaaaact tgcaactgac cattgaaagc acgattcctg
    21541 ctgaacgtgg aatgggatca agcgctgcag tcgccacagc agtcactcgt gctttttatg
    21601 attacttagc atttcctttg tctcgtgaaa tactattaga aaatgtccag ctttcggaaa
    21661 aaatcgccca tggtaatcct agtggaatcg atgcagccgc tactagcagc ttgcagccga
    21721 tttattttac aaaagggcat cctttcgact acttttcttt gaacatcgat gcttttttga
    21781 ttgtcgctga tacaggaatc aaaggacaaa caagagaagc cgtcaaagat gtcgctcacc
    21841 tctttgaaac ccagcctcat gaaactggac aaatgatcca aaaattagga tacttgacga
    21901 agcaagcaaa acaagcaatc attgaaaatt caccagaaac gttggcacag acaatggatg
    21961 aatcacaatc acttctggaa aagctgacaa tcagcaatga ttttcttaat ctattgatcc
    22021 aaacagcaaa agataccggg gcattgggtg ccaaattaac tggcggtgga cgcggtggct
    22081 gtatgattgc attagcacaa acaaaaacaa aagcccaaga aatcagtcaa gcacttgaag
    22141 atgcgggtgc tgctgaaact tggatacaag gattaggagt acatacctat gtttaaaggc
    22201 aaagcacgcg catataccaa cattgctcta atcaaatatt ggggtaagaa aaatgaagaa
    22261 ctcatccttc caatgaacaa cagcctttcg ttaacattgg atgcatttta tacagagaca
    22321 gaagtcatct tttctgatag ctatatggta gatgaatttt atctagatgg caccttgcaa
    22381 gacgaaaaag caacaaaaaa agtcagtcag tttcttgacc tttttcgtaa agaagccggc
    22441 ctctcactaa aagcttcagt aatcagtcag aatttcgttc ctaccgcagc tggattagcc
    22501 tcctctgcca gcgggctagc tgctttagca ggcgcttgca atactgctct taagcttgga
    22561 ttagatgatc tctctctttc aagatttgct cgacgcgggt ctggttcagc ttgccgaagt
    22621 attttcggtg gtttcgtcga atgggaaaaa ggccatgacg acttaagttc ttacgctaag
    22681 ccagtccctt ccgattcttt cgaagacgat ttagcaatgg ttttcgtttt gatcaacgac
    22741 cagaaaaaag aagtgtccag cagaaatggg atgcgtcgga cagtcgaaac atccagtttt
    22801 tatcaaggct ggttagattc cgttgaaggg gatctatatc aattgaaaca agcaatcaaa
    22861 acaaaagatt tccaacttct cggagaaacg atggaaagaa acggactaaa aatgcatgga
    22921 acgactttag ctgcccagcc tccattcact tactggtctc ctgacagctt aaaagcgatg
    22981 gatgcggtgc gacaattgag aaagcaaggc attccatgct actttacgat ggatgctggc
    23041 cctaatgtca aagttttagt ggaaaacagc catttatctg aggtacaaga aacatttacc
    23101 aaattattta gcaaagaaca agtaattact gcacatgctg gtccaggaat tgcgattatt
    23161 gaataaaggg agatttttat gattgaagta tctgcaccag gcaaactcta tattgccgga
    23221 gaatatgcag ttgttgaaac aggccatcca gcagttatcg ctgcagtcga tcaattcgtg
    23281 acagtcactg tagaatctgc acgaaaagtc ggaagtatcc aatctgcaca atatagtggg
    23341 atgcctgtac gttggacaag acgcaacgga gaattagttt tagatattcg ggaaaatcct
    23401 tttcattata tccttgctgc tattcgcttg actgaaaagt atgcacaaga aaaaaacatt
    23461 cttttatcct tttatgatct gaaagtaaca agtgagttag acagttcaaa tggccggaaa
    23521 tatggattgg gttctagcgg tgccgtgacc gttgcaacgg tcaaagcctt gaatgttttt
    23581 tacgcgttga atttatctca gttggagatt ttcaagattg cagcactagc caatttagca
    23641 gttcaagata atggttcctg cggcgacatc gctgctagct gttatggtgg ctggatcgct
    23701 ttctcaacct tcgaccatcc ttggctccaa gaacaagaaa ctcagcattc tatcagtgag
    23761 ttacttgccc tggattggcc aggtctatcc attgagccat tgattgctcc tgaagattta
    23821 cgtttattga ttggttggac gggtagccct gcctctactt ctgatttggt cgatcaagtt
    23881 caccgttcga gagaagataa aatggtggct tatcagcttt tcttaaaaaa tagtacagaa
    23941 tgtgtcaacg aaatgatcaa agggtttaaa gaaaataatg taacgttgat ccaacagatg
    24001 attcgaaaaa accgacaatt actgcatgat ttatctgcaa tcactggggt cgtcatcgaa
    24061 acgcctgctt tgaacaaatt gtgtaattta gctgaacagt atgaaggagc cgcaaaatct
    24121 tctggtgcag gtgggggcga ttgcggaatc gtaattgttg accagaaatc tggcattctt
    24181 cctttaatga gtgcatggga aaaagcagaa atcactccac tgccgttaca tgtctatagc
    24241 gatcaaagaa aggaaaaccg atgaatcgaa aagacgaaca tgtttcacta gctaaagcct
    24301 ttcatgataa acaaaaaaac gaatttgact tcgtacggat catccataac cctttgccgc
    24361 aaatagcagt ttctgatgtc gatctaagta cacaggcagt tgggtttaca ctaagcagcc
    24421 cattttatat caatgcgatg actggcggaa gcgaaaaaac aaaaaaaatc aaccaagatc
    24481 ttgcaatcgt cgcaagagaa gcagatttga tgattgccac tggttcagtc agcgctgcct
    24541 tgaaagtccc ttctttagcc gatacttata cgattatgcg acaagaatat cctcacggga
    24601 aaatcattgc caacatcggt gcagggactt ctgtcgaaag agccaaagaa gctatccgat
    24661 tgtttcacgc agatgcctta cagattcatt tgaatgcacc tcaagagttg gttatgcctg
    24721 agggagaccg tgattttacc aattggaaag tacttattca agaaactcaa acagccattg
    24781 acgtccccct catcgtaaaa gaagtcggtt ttggcatgac aagagaaacg ctcaatgatc
    24841 tagctgcttt aggagttcat acagttgata tcagcggtcg aagcggaaca agcttcaccc
    24901 agatcgaaaa cgcccgtcgc tccaagcggg aactgagtta tttagctgac tgggggcaat
    24961 cgacagtctc ttcattgctt gaagcaaatg aagcagacac ttctatggaa atcctagcct
    25021 ccggaggtat ccgcaatgcc tatgacatat ttaaagccct ttgtctcggc gcaaatgccg
    25081 tgggtacttc aggaaccgta ctgacgcatc tgatgaatca cggcgtagaa gaaactatta
    25141 tactgatgaa gcaatggcaa gaagagcttc gtctgcttta tactatggtc ggcgcaacga
    25201 ataccgcggc cctacaccaa caatctctga tcttttccgg accagtgaag gattggtgcg
    25261 aagcaagagg gatcgactta gtgaagtatg gaagacgcac agaaaagagc gtgggacaaa
    25321 agtaaagaac acttttgtct cacgctctaa acacgtacaa acggcggaag taaaagcaac
    25381 tccttcggaa ataagctgaa attcacaaaa atttgaaaag caattttcgt gaattccttc
    25441 ttatttcttg gagttaaatg cttctgtccc agcctctttt ttcgaataaa tgatgtttaa
    25501 tcagctgtcc ttcggtattc gttcaatccg ctgatttcac aacctctcca ctaaacagtg
    25561 tactaaagct cttttaaggt tgttttccga tataggcaag tatgcctccg tccacataca
    25621 agacatggcc gttaacgaaa tcagatgcgc tagaagccaa gaagacagat ggtccagcca
    25681 aatcgattgg ctcgccccag cgtgctgctg gcgtacgtcc aacgataaat tgatcgaatg
    25741 gatgacgttc accgttttct tgtgtttcgc gtaatggagc agtttgcggt gtagcaatat
    25801 aacctggtcc aattccatta cattggatat tgtattgacc gtattcagaa gcgatgtttt
    25861 tcgtcagcat ttttaatccg ccttttgccg cagcataagc actgaccgtt tcgcgtccta
    25921 attcactcat catggagcag atattgatga ttttaccgcc gcctttttcg atcatatccg
    25981 gaataactgc ttttgaaacg atgaatgggg catttaaatc cacgtcgatt acttggcgga
    26041 agtctgccgc atccatttcg atcatcggtg tccgtttgat gatccctgca ttgttgacta
    26101 gaatatcaac tgaacctaca tcttctttga tctgttgaac catcgcttga accgcttctt
    26161 catcggtcac atcgcagaca taaccttttg catcgatgcc tgcttcttta taatgcgcta
    26221 taccttcatc aactgattct tgattcaagt tattaaatac gatttttgct cctgctgtag
    26281 ctaaagagcg tgcaatctca aatccaatac catagacagc accggtgact aatgctactt
    26341 ttccatctaa acgaaacata tccatactaa attccatcat tttctctccc ttatgcttat
    26401 tttaattgat ccatttgcac catatccatg tctgtatagg tgatattttc tccgcacatt
    26461 gcccagatga atgagtaatt gcttgtacct acacctgaat ggatcgacca gcttggcgaa
    26521 ataatggctt gttcattgtc tacaactaaa tgttttgttt catctggttt gcccatcatg
    26581 tggaacacac gtgtatcttc attggcataa tcaaagtaga cataagcttc catacgacgt
    26641 tcatgtgtat gacaaggcat cgtattccaa gcgcttcctg gttctaaaat cgtataaccc
    26701 atttgtaatt gacagctttc gcatacattt ggatggatgt attggtagat tttacgttca
    26761 ttcagtgtca ggccttcacc agtctccatt ggttttactt ggtcgatact gatttttaca
    26821 tttggatatt tatgatgagc tggaacagaa ctaatataga atttagctgg gttttcagca
    26881 tcttgagaag aaaatacaac atgtcgtgtt tcttttccga tatagtatcc gtcttgtttt
    26941 ttcatttctt ctttttgccc atcgatctcg atgaatcctg gtccaccgat attgatcaca
    27001 cctagttcac gacgctctaa gaagtaatca acacctagtt ctttgtctaa tgtgatttct
    27061 aattcttttt cagtaggtgt cactccacca aagatcattc gatcgttgtg cgtataagtc
    27121 aaactgattt tccctggttc aaataccttt tctactaaaa attcttttct caattgttcc
    27181 gttgaataat gacggatatc ttctggactg tgtgtataac gtgtttccat ttcttgcatt
    27241 ttcttctact ccttctatcg aatgattttt ccagagccgc atgctaaaaa ttgtgcgact
    27301 tcttcttgac taaattggtt gcagtcccca tggatcgtat gcttcaaggc agaagctgcc
    27361 gtagcaaaat caatgatttc ttgcggagac atattggata aaatcccatg gagcacgcca
    27421 cctgcaaaag catctccgcc acctactcga tccacgattg gggtgattct atggacttgg
    27481 gattccacat attcatggtt catccacaat gtccccttca attcattttc acttgctgaa
    27541 tgaacggtac gcttggtcga ataaaacacc tgaatattcg ggaacttttc ctgcattttt
    27601 tgataataat aaattagagg ttgttcttct gcttctggcg ctttctcgat acctaacaaa
    27661 taaagagcat ccatttttcc agctgagcag atatctacta aaggtaaaag ctgatggatt
    27721 acttcgctgg cttcttgctg tgtccataat tttccacgat agttgatatc gaagctgatc
    27781 aggcagccag ctttttttgc agcttctatc acctgtttcg tcattttttg ccatttttta
    27841 gacaaagctg gggtgattcc tgaaacatga aatatatcta ttccttggaa taactcctct
    27901 agcgaccatt ccaaatgatc catttcagca aaacttgatc cggcacgatc atagatcact
    27961 gaggcggcgc gttcgccact accagtttcc atataataag tacctagtct tgatccacca
    28021 gataatacct gtttcgtatc tactccataa cattgcaagt gctttttgac tgcttttccc
    28081 aatgcgttat caggtacttt tgtagcaaaa atcgcttcat gtccgtaatt agctaaagaa
    28141 attgctacgt ttgcttcccc tccgccataa tgggcagcga atcgttcact tgaatcgata
    28201 cgggttccct gctctgtgga caatcgcaac atgatttctc cgagtgtcac tacttttccc
    28261 ataagcagct acctcttgat ttctttcatt tttgctgcat actgttgcgc gacttccgtt
    28321 actttgtcaa aatctcctgt agctgcgggt gctaaaaggt tcccacctac tccgactgtt
    28381 acgacaccag catcgaacca ctctttcata ttgtccagac tcacaccgcc agttggcatg
    28441 atattgactt gaggcatcgg cgccttgaag gcagaaatga tacttggtcc ataagcgctt
    28501 ccaggaaata gtttgacgat atctaccccg cttttcagcg ctgttttgat ctcggtaata
    28561 gtcatacatc ctggtaagta aggaatttga tacagattgc acatctctgc cgtttcttga
    28621 tcaaaggaag ggctaacaat atactctgcg ccagctaaga tagccaagcg agctgtgaca
    28681 gcgtctaata ctgtgcctgc gccaatcact atttctggtt ggtctttgta gaatgacaaa
    28741 agttctttga ttacttgatc tgcttgaggg actgtaaaag tcaactcaat accagttaga
    28801 ccacctttga tgattgcgtg gcaagcattc aaagcttctt ctttgctttt tccgcgtacc
    28861 accgcaatca ctccggcgtt tttcaatcga gataaaatat caattttttt catcttctcc
    28921 acctatttcc tatttagaaa ttttatttta taacttggaa atctataccc atattatacg
    28981 gcagaaaaga aaaattgcaa acgctttttt cattattttt gaattctttg ctcgatttcg
    29041 ctttttgttt gcttgagggc actgattatt tgttcttttg tctcatctgt taaacgatat
    29101 ttcggcatac ttacactaaa tgcaccaatg atttgttcgt ttttcacgat tgaggctcct
    29161 atacaaaaaa tatcacgttc gatttcttca tcgtcaaatg cgatgtgggt ttcttttacc
    29221 gttttgattt cctttttcaa ccgtaatgca ttggtgatcg tatattctgt gtaagggatc
    29281 aacggatgct tttcaagata atcagtgtac tgctcttcac tgaattctgc taatacggct
    29341 ttgcccatcg cagaattgta taatggtcgg gtgattccga tttttgaaga catgcggatc
    29401 gtttgatgtt ttggatctag tttgttcacg tacaagatct cattgttgtc caatacccct
    29461 aagtggatag tctcatcgat cttttgctgc agctgttcta aaaacggtaa agtcaactct
    29521 accaaatcga tttgttcaat gtttttattc gcgtagcgaa taagctttgc acctaaacga
    29581 tagtttttct ctgaattttt atttacgtag ccgatcatca acaaagtatc tagtattttc
    29641 aagactgtag aagaggtcat tcccacaccc tttgcgatcg tctgcaaaga gacatcttgg
    29701 ttttccgcta aatagtctag tattttagag gctttgatca atacagttcc ataaggcttt
    29761 ttattttcca tataatattc tcctatttct ttataagaaa aattatagcg gaaataccat
    29821 caatttaaaa gagatatcca gatataaact accatttctc tttacaggca atttaatgtt
    29881 gaagatccgc ttcgttttta catcaaactt tgatataaag caatgatttc ttctactgtc
    29941 gtttctcttg gatttcctgg tgtgcataca tctcgcaaag catcttctgc aattgctgga
    30001 atatctgctt cttttacacc taattcagaa atggtttctg ggattccaac cgctttgctc
    30061 aaccgatcga tctcaccaca agccgcttct cttacatctt ctaaagacat ttcagctgct
    30121 cctttaatcc ctagaacaag agcgatctca cggtactttt ctccagtata ttctttgtta
    30181 tatttcatga cagttggcaa aagtgctgca cacgctacgc catgaggaat gttgtaccat
    30241 gcacttaacg ggtgagccat cccgtgtacc agtcctaaac cgacatttga gaagcccatt
    30301 cccgcaatat actgtcctaa tgccattttt tctcgcccat tttgatcgcc atctacagaa
    30361 gcttccaaag aatggccgat gatttcgatt gcttttaaat gcagcatatc agtcatttcc
    30421 caagcgcctt ttgtgataaa cccttcaata gcatgcgtca tagcatccat acctgttgat
    30481 gcagccaatt ttttcggcat tcccatcatc atatcgctgt cgatgaacgc gacgattggg
    30541 atatcatgag gatcaacaca aacaaatttt cggtgattta cttcatctgt gatgacgtag
    30601 ttgatcgtta cttctgctgc tgttccagaa gtcgttggta tagctaatat aggtaaacat
    30661 ggatttttcg tatcagcaac accttctaaa ctaatgacgt ctgaaaactc tggattcgtc
    30721 aaaataatcc caatggcttt tgccgtatcg attggcgaac ctccaccgat tgcgatcaaa
    30781 cagtctgcct ctgcctcttt aacaaaagcc actccatctt ttacattttg gatcgttgga
    30841 ttaggtacga tcccgtcgta taaagcataa gcgattgctg ctttatctag aagttctgtt
    30901 acttttgttg ctataccgtg ctcgatcaat cctttgtcag taatgacagc tgctttgccg
    30961 aatcctcgct gctgaaattc agggacgatc gactcaatcg ctccttttcc aaaatacgat
    31021 gtttcattta aaatcattcg attactcatt ttctattcct cctaatttgt attatttttc
    31081 acaataaaaa cgaaagaacc ccaagcaacc ggttgcccag ttgcttgttg ctacagttca
    31141 aagactggca tcaattccca actgactgga gaggcatctg gatttgtctc catgatatct
    31201 tccatgtact tccaccattt ttgattgata gatgtatttg ccattttttc ccataacttt
    31261 tcatcttcga tcactaagta accaaataac aaacttgtac tcggatcaag atagatcgaa
    31321 tagtcgatga ccccgtgttc acgaagtgct gtacgcattt ctggccaaag ttcatcatgt
    31381 ctttttttgt attcttcttg tttttctggg taaactttca tgcaaaaagc ttttttcacc
    31441 atgtcagaca cctgctttcg tatgaacttc ctccaaataa cctgcttttg gagtgacacc
    31501 aaacgcatct gctaaatgcc acaggttttc gtccgtgatt gtttgcaaga ttggtccttg
    31561 cgctttgacg tacgtataga cttctgctgc cttttctgct gtctcgatca aaccaaagac
    31621 ttcatccatg tcttttcctg acccgtagat tccatgttgt ggccataaaa ccaatcgagt
    31681 ttctttcatt ttttcagctg ttgcttcccc aatctcattt gttcccggaa ccatccacgg
    31741 aatgatggaa attccttctg gaaaaacaac taagcattcc gtacacattt gccatagcgt
    31801 acgactaaag gaacgttcgt ctaattcatg cgtaaaactc atcgctaata gatgactagc
    31861 atggcaatgc ataacgatcc gattatctgg gtctacttct aaacgggcga tatgactcat
    31921 gaaatgactt ggcaactcgc ttgtaggaag gcattcgttt tccagccccc acaaaagttc
    31981 cagtgttttg ccatcttcag caactcgaac gattccaaga ttctcggcag gttcgctcgc
    32041 tacattttta aaatatcttc ctgaaccagt tacaataaaa tagcatcctg ctaaacggct
    32101 ggcatcaaaa atcatcgaga tgcggcggat cactttttca ggatccaaga acggtgtgat
    32161 ctcttcttct tttagtaaat aagaaatatt cccgccattt ctttcatccc atcccaagcg
    32221 ataaagattc gacgtcgttt cgatcatttc tttcacataa ggcgcttgta aaatatctat
    32281 ttttttcaat atagccacac tcctattttc ttaattccaa cacgtctttt tgatattcct
    32341 ggacttcttc cagccaatcc aaaccaactg gaacttgatt tttgtaacag aaataattcc
    32401 atacatcggc atacgggaaa tctttcaatt cttccgtata agccattctt gaagtaaagt
    32461 caaaagccag ctccatttct ttcaatcgct caactggttc cagcatagct ttcagcagtg
    32521 ctttttgtgt atttctcgta ccgatgaccc aagcagcgat acggttgatc gttgcatcaa
    32581 agaaatccag accgatattt gttttttcca acaattcgtt acggactaat tctttagcga
    32641 tttcctgcaa ttcatcatcc atcaaaacca catggtctga atcccaacgc actggacggg
    32701 aaacatgcaa catgattcct ttgctgaata aagctaatga agataattta ttggaaatca
    32761 cttctgttgg atgaaaatgt ccagcatcta gacaaacaag tttgtcacga gtcaacccgt
    32821 aacccatata aaattcatgg gaaccgactg tataagcttc agcgcctaaa ccaaatagtt
    32881 tgctttctac tgcatcttgt acataccgtt catctaactc ttctgtaaaa atttcatcga
    32941 gtgattccat taaacgttcc cgtggggtaa aacgatcaat cggattatct ttcatcccat
    33001 caggtaccca aaagttattg atacttgttt gcccagtttc tttcccaaag tactccgcga
    33061 ttttgcggct tcttttcccg tgttcgatcc agtattcacg aacttcttta tctggatgag
    33121 ccaatgtaaa gccgtctttc atcattggat gcgaaaagaa agtcggattg aagtcaagac
    33181 cgatttcttc tttttttgcc cactctaccc atttttcaaa atgtttcggc tcaatttcat
    33241 ttagatcgac agattcttct gtatccaaat agatagcatg aaggttcaat ttgtgtttgc
    33301 ccggtatcaa cgaataagcc ttctccagat cttgtctaag ctcttcaggt gttcgtgcgg
    33361 ctcctggaaa attccctgtc gccatgattc caccggtcaa ttcgccatcc ggtgtcaaga
    33421 aacctttgac atcatctcct tgccagcaat gcatagaaat tttgatgtcc tgtatctttt
    33481 ctagtacagc atctgtatct acaccgatag ttgcatattt ttcttttgct tgttcgtaat
    33541 ttctttcaat cgtgttcata cgattactcc tttgatttta ttcacgtacc attccatcgt
    33601 gttttgctta ttttcatctg ggtaaaaagt ttcacatgga aacgactgtt tgattacatt
    33661 tcttgcttgt tctatattcg aaaactgacc tgtactgagc atttgcatgg caacattccc
    33721 gattgctgtg gcttcactag gtcctgcttc tacaatgatt ccggcataat ctgctgtcaa
    33781 ttgattcagt agacgattat tcgatccgcc ccctacgatg tgcagctttt ccaatttcgt
    33841 tccagttaag tgttctactt tgatcagctc ttgtgcgtaa caaagagcaa gattatcata
    33901 cacacaacga gcgatagctc ccgatgagac agggactggc tgctctgttt caaaacagta
    33961 ttgctgaatc tcttctatca tatttggggg attcaaaaat cgagggtcat tgatttccat
    34021 cacttgctgc agcggttttt cttttgcagc aagctctgcc aattccgcat aactgtactc
    34081 gtactcttgc attcgggcaa cttcctggat caaccacatc cccatgatgt ttttcaaaaa
    34141 acgcaccgtg ttatgggcac cccattcatt cgtataattt tcagaaaaag cattgcgaga
    34201 aacattggcg atctttgttt caatccctaa aagcgaccat gtcccactgc tgatataacc
    34261 ccaacgttct ccttgacctg gcgttcctaa tacagctgac gccgtatcat gacttgctac
    34321 tgtgataaag gtcacatctg gcaaatcata ttttgaaaat tgttcttttt gcagatctcc
    34381 tagtatcgtt cccggctctg tcaatggtgg aaataattcc ttcgagacac cgattttttc
    34441 aagaagttct atttcccatt cttttgtccc tgcattcagc agctgcatag tagatgcatt
    34501 agttttctcc gtcaccatgt taccagtaaa gacataccct aaataatcag gtatcagtaa
    34561 caatttatgt gcttttgcca aattttcttt ttcttcagca aacaattgga acaaggtatt
    34621 gaaaggctgg atctgaatcc ctgtctgctc atacaactta tctagagaat agatttcaga
    34681 aaactgttct actgctccat tggtacgctt gtcccgataa gcaatcggat catttatccg
    34741 atccccttgt tcatcaatca gacagtaatc gactgcccat gtatcgatcc ccgcaaaaag
    34801 gcgatcaatc cctgtctgct ttaatttttc aaatccaatc aaaatctctt tgataagata
    34861 atcgatcttc cagcgatcgt gaccgtcttt gttccgaaag ccgtttttga accggtgtac
    34921 ttcttccaag atcaaagaac cttttgcatc cctcgtactt ttcattagtc gtccgcttga
    34981 tgcaccgata tcgatggcaa caaatgttgg attcatttct ccacctcttt tactttattg
    35041 ttgattagca ctttattaat aaagcgttat catttattga caatgctatc ataatacaga
    35101 atcttatatt ttgcttcaca ctattttggt atataattgc attatcttga caagttggga
    35161 gtgtttacat ggattactgg gaaaaagcca accactcatg gtcggaagac tcaaaaagag
    35221 tgatcttgac gcctacacaa agaagcagga atttattttt ttatatccaa gaaatcggtt
    35281 acttcaaagc accaatccct tactatactg aacgagcaca tttaccttct tacttgataa
    35341 agtttacttt gtctggcaaa ggttcgctta catataatga taatcagcaa cagctaaaag
    35401 ctggagactt attttttatt gactgccaag aatatcagcg ttatcaaacg atcagcgaag
    35461 aaccatggga aatggattgg atccatttga atggtcagaa cgtccaatca ttttatcagg
    35521 agttcacaaa agacggccat aacaccttcc attcaacagg agatccatca gaaaacaaga
    35581 tccaccattt gatcacagaa ttgatccaca tgcaacaagg cacgaatgcc cgtaccgatt
    35641 tccagtcctc tgtagctatc cacgagttgc tgaatgaact gattttgcaa aagtatcagc
    35701 tagatttcga agaagaggat attcccgcct acgtttacaa actgaagcaa tacttagacg
    35761 aacatttcaa agaaacgatt acacttgatc aattagaaca acaattctta ttgaataaat
    35821 atcagctgag caaagatttt tccaaattta tcggttctcc accaatcgat tatttgatca
    35881 gcaaaaaact ttcttacgct aaagaccttc ttcggtatac agaatttacg gttcgaatga
    35941 tttccgaaga aatagggatt gagaattttg cttactttag ccgcctgttc aaagcaaaaa
    36001 caggactatc gccgagagac tttcgtaaat tcagctgatt catataatat gtacgtcatt
    36061 ttttcaaaat attttgaaat atatagataa aaataaaata accgcagttt ctgcttctat
    36121 gtaaacaaca gcagctactg cggttatttt ttagtgatca ttctcattgt tcatcttcaa
    36181 aatgttcata atgaaccaac tgtttctgtg tatcacgttt caaaaattct ttaggcgtta
    36241 tgccgaactc tctcttgaat gctttcagaa aatgcggata agaagaaaaa ccacttttac
    36301 tatatacagc actagagctg cggtattctc gcaacaagtg cttggcatag atcagctttt
    36361 tcttcattac atactgatga aacgtaaatc cagtgtactt tttaaattct cgtgtgatat
    36421 ggtatttgct gacaaaaaac tgcttttcca tttcctctaa agaaagcgga tgagataaat
    36481 tttttgagat atattgtaac atttgttcca cacgctcatt aggaactaca gcattctgtt
    36541 cttgcgcact ctcttctttt tgtacaactt gattgagaaa aatcaagtat tctaccagag
    36601 cttgttcata ttttatgtct tcaccgtaaa tttttttatc aggaggatgg tcgataaatg
    36661 ataatttttg cttcaatact tcctgttcta tttgcaatac acgactcctc ttctctccca
    36721 ttggttgaaa acaagccgat agattagacc atggcgtgga acgactttct agaaaagaag
    36781 gggtgacaaa gatatagaca cgctcgaata catctgaaga ttggcggacg atacgatgca
    36841 aatcattgga atggatgagc agcacacttc ctgctttgat cgtaaattgt cgtccgttca
    36901 aataaaaagt cgcttctccc tttaatgtag catggatctc atagaaatca tgatgatgat
    36961 agatcgtttt attttggctg acgacatctt tgacatgata gatttcatac tgatcagaaa
    37021 ccatcgtatt gacttgttca ccgctgattt tcttttggag catgtgccgc acctcctttt
    37081 gttcacttat gcacaatttt attataccac gttttttgta atcaaaaaga gctgctttta
    37141 tatactctta taaaaaagaa gagacgtggc atcttctagc cccgccccct ccattctaaa
    37201 tattagttaa ccaacgtctt ctttacatta ttcaagaaga cttcttccat aacgaatccc
    37261 atcatctttt gtttcttcaa gaaccacata caggtacgga cgattcttca tgatgatttc
    37321 tttgattttt gtgtactcga tcacaccgtc tcccaaattt accggcacga ttttttcctg
    37381 ttcgacacga aaatctttca aatgaaccgc acatatcttt tcaccaaaac gttcaaaagc
    37441 ttcttctacc aattggactt gttcttgata atcactactt gtgatcaaat tggtcggatc
    37501 taaaatgatt cctagatagt ccgaatctac tgcttggatc agctgctcta cccttgctaa
    37561 agaatacacc ggatgattca aacctggttc tatccccacc atcatttggt atttttctcc
    37621 agcttttacc aagcgacgga taacggacac agcttcagca aatgcttcat ctgtgaaatt
    37681 ttcttccgta tattggattt ccggcaaaac acatccagtt tccgaagcaa ccatcgacgc
    37741 accaaaggaa gaagcatagc gaagatactg ctcgaacttt gtcagcaact cttgtcgtat
    37801 cgttaaatct ggatgaatca tattgatata gcaacttaaa attcctacgg tcacttcttg
    37861 cttttctaaa actcgtttga cataatttcc catcccagaa ttgatctcat ttgcgccaga
    37921 aggtatttca ggaaacgaaa gacctaaggc gagctgcagt gtatgaatcc cttgttcttt
    37981 tgttttttct gcaagatctt ctatcgtttg gacttcggaa agatcatgtc ctctaattgt
    38041 aatgttcaac ataactattc tcctaactca gcatattggg tagccacatg acgatttgcg
    38101 ggaagtaagt aatcaaaaac aagacgacta agataacccc ataaaaagga agaagcggtt
    38161 tcagcattgc ctctgctttt acgcctccta cacttgcacc gacatatagt cctgtaccta
    38221 ctggcggcgt gatggagcct acacacagat tcatgattga aaacaacccg taatgtacag
    38281 gatcaacccc tacacttgtg acgattggta aaaatattgg tgtaaaaatc aagatagcag
    38341 gcgccacatc cataaacata cccaccagta ataacacaag attgactaat aacagaataa
    38401 taaatttatt atccgttacg cccataatca acgaactaat tgcctgagga ataccggtaa
    38461 acgccatggc gaaagacatc atggaagaag tagccaataa gaacatgatc gtccctgaca
    38521 ttgctactga ttgaaacaac atattaggta tatcttttag ttttaccgtt ttatagtaaa
    38581 acatagcaat caacagggag taaatgacag ctatcgctga agcttctact gctgtaaata
    38641 tccccgtcaa gataccaccg ataatgatga caatcaatag aaggctagga atcgcctctt
    38701 ttattatttt tccagcatga gccatctgtc ctttttcgac aacagggtat ttattctttt
    38761 tagcaacgat gaatgctact agcatgattc ctagcgccca caaagcgcct acgagataac
    38821 ctcccataaa caaagcagag atcgaagcac caccagcaac aagtgaatac atgataaaag
    38881 cagtacttgg aggaatgacc atacctgtcg gagctgacgc gatattgacc gctgtcgcaa
    38941 acttccggtc atatccttct tccacttgct gagggatcaa cactccgcca atcgcggtag
    39001 aagcggcaat ggccgagcta gagatggaac caaataaagc attccctaac acattcgtat
    39061 gagccaaagc ccccggcacg cgcccgacga acaacatcgc aaaatccact agtttcttag
    39121 ctatccctcc attattcatg ataatgcccg agagaacgaa aaacggaata gcgatcagcg
    39181 aaaaactatt gatacttccc accatttttt gagctgaact aaaagcagaa acatcaaacg
    39241 gtataactaa caataaagtc atcatcgatg agaatgcaat acttatagca atcggcatcc
    39301 ctaatacaag caacacaaca aatacaaaaa ataacactaa tccggcttct attgccattt
    39361 tattcctcca tttttatatt ttttcttgaa ttgctggctt gttgcttaat gtatcgatta
    39421 gattgatcag gctatagata atgatgagta cccccgatac aggtactgac agataaacat
    39481 atcccatagg aatacttaaa gaaggcgaga tctgccccat tgtcaatgtg acagcattcc
    39541 atccgccata caccatgatc atcgcagcaa ataccagaaa taaactttga acaacaactt
    39601 ctaaaatttt actttttttg ccagttaatt tttcacttaa aaccgttacg gctaaatgtg
    39661 ctttttgtcc cacaacatac gcggaagaca acatggcaaa ccagacaaga ccgaatcgaa
    39721 caagctcttc cgtgaccgta tttggatttc ctaaaaccgt tctggaaaat acttgccata
    39781 aaacaacagc gaccatccca acaagcaaaa cagctcccag gatctctaat accttgttta
    39841 aaatcatttt catcacagct acgctccttg ctcttggatc ttttgataaa ggtctttgta
    39901 ggtaggatcg tttttgaata tatcatgaag tggggcaact gcctctcgaa acggtgtatt
    39961 atctacatca ttgaattgga ctccatgttc ttcttgtgct aaagcttttt cttcttcaat
    40021 tgcttttgca aaagcttcaa tttcaaaaac cgttgattct ttcgctgctt cttcaatggc
    40081 tttttcctgc tcatcagtta gctgttcttt gatggcatca ttcatgatga tgatatctgg
    40141 cacacgtgta tgctcatcat aggaatagta tttagccaca ccaccatgtc cagctgtata
    40201 caagacaaat tcattgtttt ctgatccgtt gatcaaattg gattgaagag acgtgtacac
    40261 ttcatcactt cccataggta cgggcgaacc gcctaaaagc tctaccattt tgatagcggt
    40321 ttcgctttgc atcacacgga tcttctttcc cttcaaatct tccggcgtat ggatcggacc
    40381 gtctaccata taaaagctgc gctgaccaga atcataatag gtcaatccgg taaatcctaa
    40441 atttttggtc gattggtaga ttggctccat tatttcttca ttatccatca ccttaaagaa
    40501 atgttcttca tcattgaata gataaggaac tgaaaaaatc gaataatctt tagagaaact
    40561 ttccaacgct gaggcactta cttttgtgaa atctactgct cctgactgtg tcaattcgat
    40621 cagttcacgt tctccaccca gttgtccatc tgggaaatac tggatctgta cggaaccatc
    40681 tgttttttct tttactaaac gcccaaattc attcattgca tcaattactg gctggctgtt
    40741 gcttgcataa gcaaagcgca aggtaactat ctcatttaca tctgcatctg cgacagttgc
    40801 cacactagaa ttatttccgc agccgcttag acctagcaga cctaggctaa gcgaacttgc
    40861 tgcaaacagc agtgatgttt ttttcatatg ggtttccttt cttttaacaa taagagacga
    40921 gcaattctgt caaacaaagc accgttaacg actgtccata aggcattgct gtgattccga
    40981 tattccgata aaaatctaaa ctgtccccca ttcctgtccc gattgaaacg ttttgaactt
    41041 ctcctttttc atcgatttgt tcaagcaatc cttggatagc acgataagcg acttctttat
    41101 attcttgtgg taaataacgt ttatggaccg ctttcaaaat accgtaagca aatcctgcag
    41161 ttgcagaaga ttctacgtaa gaagaaggat catccaacaa cgtatgccat aaaccgcttt
    41221 cagactgata agtttttaat gcacgcactt gtgcttcaag tgtttcgatc aataatttgc
    41281 gcaatgcatc ttctttcgat aattctaaga tttcaatgat ctctggaata gcaatcgtca
    41341 accagcagtt tccacgagcc caaaatgctt cggcatagtt atgatttcct tcaaacgtcc
    41401 agccgtgata ccacaatcct gttcgtttat ccatcaagta tttgatatgg atcataaact
    41461 ggtaacgagc ttcttctaaa tattctgggc gattcaacag tttcccgatt tttgccaaag
    41521 gaagcactgt catcatcaat gtatcgtccc acaactgatt cttattttcc ggtccatatg
    41581 tggcatgctg taacccgtct tcatttgtcc gaggcatgtc attcatgacc cattctgccc
    41641 attgttctaa ataaggcaaa tagcgtgaat ctttcgtgtc ttcatacaag taagccatag
    41701 tcaatagcgg tgccattgta ttgacgtttt tgggcggagc gccttcttcc atacgatcct
    41761 caaaccattc attgaccact tgataagcgc gaggattttt tgtcatctgg taatttttat
    41821 aaataccata tagaccgaca ccttgtggcc aattccacac tgtccagctt ttgtcatcta
    41881 ctttcagtcc atcaaagtcc aacaaaaatt caccattatc gtctttgatc gttgtcaggt
    41941 tttcaacgag caggtcaatt ttttctttca ctaattcttt aggtacaaaa atctcttctt
    42001 taataatcat ctttacgcca cctttttaaa cgctttcatt ttatatcctt aatatagcag
    42061 taataccgtc cactataaat atcgcttttt gaacaaaaac tgtctaaaat tgacctaaat
    42121 gttaaataac aaaagtaact ttcagttact tggaaattaa aaaaagaact tggagaaaca
    42181 acgttttcca agttcttttt catctatttt cttatctttt ttctacgctt tcttttgctt
    42241 atccgttgta agcatcaatg atgatctgtt tcaattcaga gatcaatggt tctttcggat
    42301 tagctgtcgt acattggtct tcgtaagcta attcagccat acggtctacg gttgtatcta
    42361 gtgtttcttg tgtgactcct tgagctttta gactcatgtt gatgccgaca gattttccta
    42421 attcataaac agccgttgct aaagcttcga ctaattcctc tgttgtttcg cctttcagac
    42481 ctaagaattt tgcgatatct gcgtaatctg tatctgcacg gaaatagtca tatttaggga
    42541 acatcgcatg tttttgtgga tcttttgcat tatagcggat aatatgcggt aaaagaatcg
    42601 catttgtccg tccatgaggg atcccgtatt ccccgccgat tttatgtgcg actgagtgac
    42661 aaatacctag gaatgcgtta gcaaacgcca taccagccat tgtagaagcg ttgtgcattt
    42721 tttcacgtga ttccatatca ggtgttttta ctgatttttc taaatagtca aagactaact
    42781 tgattgcttg taggctcaat ccacgtgtat aatctgaagc catgactgaa acataggatt
    42841 cgattgcatg tgttaacaca tccatcccgg tatctgctgt gacagatgct ggaactgaca
    42901 tgacgaattg aggatcgacg attgcgacat ctggcgtcaa tgcataatct gctaacggat
    42961 atttcacatg tgtttcactg tcagtgatga ccgcaaatgg cgttacttca gaaccagtcc
    43021 ctgatgttgt cgggatacat acgaattgtg ttttttctgg tttgtcgatc ttatatgtcc
    43081 gtttacggat atccaagaat ttttgttttg caccaaagaa agatgtgtct gggtgttcat
    43141 agaacatcca cattccctta gctgcgtcca ttgcagaacc gcctccaaga gcgattactg
    43201 tatctggctt gaagtctgcc atcagtttcg ttcctgcgta tacggtattt gtcgatgggt
    43261 tcggttcaac atctgagaag acttcgatct tcacatcatt tttacgtcgt gccaatactt
    43321 cacgaactgt atcgcagtaa ccgaattgga ccataccagg gtcacaaacg atcatgacac
    43381 gttcaacgtt ttccattttc tctaagtaca atagagagtt cttttcaaag aagatttttg
    43441 gcggtaattt gaaccattgc atgttatttc tccgtttcgc tacagttttg acattgatta
    43501 agtttacagc agagacgtta cgagaaacag agttcttacc ataagaaccg catcccaaag
    43561 tcaatgacgg aatcatttcg ttatagatat caccgatgcc gccttctgca gatggtgtat
    43621 tcactaaaat acgacaagct ttcattcgaa gaccgaattt gacatgcaac tcttcgtttt
    43681 ctgaatggat aactgctgta tgtcctaatc ctccaagatt caacatacct tcacacaaat
    43741 caaacgcatg gtccgtgttg ttagctttga tcatggcaag aactggagaa agtttttctc
    43801 ttgatagcgg ataatctggg cctacgcctt ccaattcagc aatcagcatt ttcgttcctt
    43861 ttggtacact gattcctgcc aattttgcga tttccatcgc agaatgtcca acgattgatg
    43921 gattgaccgc atattttcct tcgttcatca ctgcatcttc taatttttgc aattcatctg
    43981 gttttacgat ataaacttgg tgtgcttgga attctgcttt tactgctgca tagatttctt
    44041 tatccacgat cacagcttgt tcagaagcac aaatcattcc attatcaaat gttttcgaaa
    44101 cgatcaaatc gttcactgca cgtttaattt ttgctgtttt ttcaatataa gctggtacgt
    44161 tacctggacc tacacctaaa gctggttttc ctgtagagta agcagacttg accattccag
    44221 ctccacctgt cgctaagacg atcgcgatac ctggatggtt cattagcata gaagtcgctt
    44281 cgatcgaagg atgttcgatc cattggatac aattttcagg agctccggca gcgatagcag
    44341 catcacgtac cactcgtgct gcttctgcag aagatttttg ggcacttgga tggaaagcaa
    44401 aaacgattgg atttcttgtt ttcaacgcga tcattgattt gaaaatcgtt gtggaagtcg
    44461 gattcgttgt tggagttact ccgcaaacca caccgactgg ttcagcaatt tcaatcaacc
    44521 ctttttggac atcttcattg atcacaccaa ctgttttatc atgtttgata ttatgccaaa
    44581 tatattcgga cgcatacata tttttgattg ctttatcttc gtaaacaccg cggcctgttt
    44641 cctctacagc catcttcgct aatggcatat gttgatccaa agctgccatt gccatttcat
    44701 gcacgatatg gtctactttt tcttgatcaa agctttccat ttctttcaat gctgcatttg
    44761 ctttttctgc caaatcatca atcattgctt gtacgtcaat tgtcttcgtt ttttcttttt
    44821 ctattacttt agccatcatt atcctcctaa tgggtcatgg ttatttgtta aataattcac
    44881 atgtatatca tacaatattt atttttctat gtaaacactt ttttgtgatt tttttcacag
    44941 ttatttttaa atataaaatt gctttattta caggtgtttg tatagaaaaa tatataaagt
    45001 tatttattat tatttatatg acacacccga ttattcaata ttgagcaata tatcccatgc
    45061 tcttatctct ttcttttttg aataaaaaat gaggtaggac atctttctgc cctacctcgt
    45121 ctttaaataa gctttgatac ttatttttct tccttctctt ctgtctcttc cagcgtttct
    45181 gttgtttcag tttttacttc aactgtctca gctggttctt ctgttgtttc aacagtagtc
    45241 gttgcatcat ttgttacgac agtccctggt ttgaccgttt tgattgctgc acgatcgtac
    45301 tcaaggaaga tcccttcgca gtctaaaaca actgtccgtt tgtcattgtc gatttctgaa
    45361 acaactccat gtaatccgcc gatcgttacg actgaatcac ctggtttcat gctatctaac
    45421 aagttttgac gttcttgctg ttgtttcttt tgcgaacgtg acataaaaaa ccacattgct
    45481 aatagcgcga taaacatcac aagcattggt aatgttccca tttttttcac ctcactaatt
    45541 ctgtatctac aaaaaacact ttagcagaaa aatgctgata acactagttt tttacttaat
    45601 ttttaaaaga ttttccttta gaagcttttt gcgttttctt tattgaaccc gtattcttca
    45661 aaaaaggctt ctctaaattc aagcaaatta tcatccatga ttgcttgacg tacttgtttc
    45721 attagattca acaagaagta taaattgtgg taagaagtca aacgaatccc aaatgtttca
    45781 tcacatttga tcaaatggcg gatataggca cgtgtatagt ttttacatgt ataacaatca
    45841 catttctcat caattggacg gaaatcatgg gcatatttcg catttttcac tactagacgg
    45901 ccttgagaag tcatacatgt gccatttcga gcgattcgag taggcaagac acagtcaaac
    45961 atgtctactc cacggataac accatcgatc aatgaatcag cagcaccgac acccatcaag
    46021 taacgtggtt tgttttcggg gatcaacggt gtagtgaatt ctaatacacg attcatttct
    46081 gatttaggtt ccccgacaga taacccgccg attgagtaac cagggaaatc catcccgact
    46141 agatctttcg cgctttgacg acgaagatct tcaaaccctg ctccttggat gattccaaat
    46201 aatccttgac ggtctggatt agcatgagct ttcaatcctc gttctgccca tcgagacgta
    46261 cgttctactg attttttcac gtagtcgtaa ctttcatcga atggtggaca ttcgtcaaaa
    46321 ctcatcatga tatcagagcc caatttattt tggatgttga ttgctttttc tggtgataaa
    46381 aacatacgcg aaccgttcaa gtgatttttg aaatgcacgc cttcttcttc gatattccgc
    46441 atatcactta atgaaaaaac ttgaaagccg cctgaatctg ttaaaatcgg ttgatcccag
    46501 ttcataaatt tatgcagtcc gccagcttct tctactaagt cttcaccagg gcgtagccat
    46561 aaatgatatg tattacttaa aataacgcca gcacccattt ctttcaactc ttctggggac
    46621 attgttttta ctgtagctaa tgttcctact ggcatgaaca ttggtgtggg gaaagttccg
    46681 tgtggcgtga tcaattcccc taaacgcgcg ccagtatgtt tttctttctt gattaaacga
    46741 tagcgaatgg caggttgcgt cattcatttc cctactttct atataaaata tcttgacaac
    46801 tcccaccatc ataatcgttt caagtgcttt ttgcaagttc cctcggcttc cttctacttt
    46861 atttaatatt ctttttttta tccttttttt atgaataaca aaaaaaagaa aaacattatg
    46921 acagaaatat tttttgatac atggtatatt ggtgttatta aagaaaagga gggaaaaatc
    46981 atgcaatctt ctgcagaatt aaaacgccaa gcaaaagaga gtctaaaagg acgttgggga
    47041 caagctgttt tactaaatct aatccctaca ttgattggta ttgctactat tcttcttatt
    47101 atgattccta ttatcttgtt tgccaccacc atatatgatg gatcagcgag cgtctcagaa
    47161 gcgacaactt caggaggcgg tagttcagga ggcggtggcg gaattatttc cagcatcatt
    47221 agcgctttgt tcatgagcgg tatttcttgg acttatcttg atattttacg tggacaaaaa
    47281 gatcagatcg aaccattcaa agatgcattt cgtggattca aaggtttgtt tatcggcgga
    47341 gtgatcagct tagctgtgct gatctcgatc tttacaacat tatggggttt gctattagtt
    47401 attcctggaa tcattaaaag ctattcttat tctcaaagct attttattta ctacgatatc
    47461 gtccaagaaa caggacaaac acctaaagta ctggatacga tcactgcaag tcgaaaattg
    47521 atggatggtt ataaaggaca acttttctgg ttagatcttt catttatcgg ctggcatatc
    47581 ttagcattag caactgctgg tattggttat ctatggctca gcccatacat ttctgcaaca
    47641 aaagcagcat tttatgaaca attgccaaaa gatatttaaa agagagtgtg acttgtgacc
    47701 gagggggtgg caggagaaca ccgtttatcg agaggcagta aaagaaacat tcagcccatt
    47761 agcaaaaagg aggtgtgaca acattcatgt cacacctcct ttttgtatag ttccagtaaa
    47821 aagaaaatca acttagaaac agttaatcat tcctcttctt ctgcttccgg taatcgatgg
    47881 aacttgatca gttcattcac cgcgattggt acgatagata aaatccctac caagaaccag
    47941 tgattcaaac tgatgtgtac taggccgaat agttcttgcg taaatggcag caaagcaaca
    48001 gccgttgtaa tagctaatgc cagtaacgcc atttctacca aagctttatt ggtcgctaaa
    48061 ttgactttga agatcgattg gctgctgcgt acattgaaca catgcagaat cgatgaataa
    48121 gctaagatca agaatgcaac agtttgaccg acatgctgac ttgcgtctac ccatgggctg
    48181 atagtatcga cataactacc taaataataa ccaaacaagg ttacgatggt gaagacccct
    48241 gcatttatgg caattttttg caataaacct cgagcaaaga tcccttcatt tttcggaatg
    48301 ggtggctgat ccatgatgcc gtgttccgct ggctctcttc ctaaagcaaa tcctggaagt
    48361 ccatcagcaa ctacattgac aaacagtagt tgcacagctg taaatggtgc tccccatcct
    48421 aacagcatcg caatcaaaac aataaagatc tccgaaatat tacagcttag caaaaagttg
    48481 atagctttac gaatattctg ataaaccgaa cgtccttgac tgacagcgtc tacgatcgtc
    48541 gcaaagttgt catccgtcaa aatcatatct gcggcacttt gcgccacatc tgttcctgtg
    48601 atccccatgg cacacccaac gttacttgct ttcaacgctg gtgcatcatt cacaccatcc
    48661 ccagtcatcg ctacgactgc acccgtacgt tgccaagatt tgacgatccg gatcttgtct
    48721 tctggcgtta cccgagcata gacagagaga gctttgacac gcgcatctaa ttcttcgtct
    48781 gataattgat gcagttctga tcctgaaagt gcttctgacg gatcattcaa gatacctaat
    48841 tctttcgcta tggcactggc agtcaccaca tgatctccag tgatcatgac tgttttgatg
    48901 ccagcctttt tcgctcgctt gattgctcct ttactttctg gacgtggtgg atcgatcatt
    48961 ccgatcagac caatcaaacg taagtctttt tccagtgctt cagaagaaat atcttgcggt
    49021 tcttcgtcat aagtagcata accaacagca atcactctca gtgcccgttt accaaagcga
    49081 tcattaacga tcgccgcttg ttctacatcg cctgaactaa agcgcggagc aagaacatcg
    49141 aatgctcctt tggtgattga gatgtatttt tcgcccattt ggtgaactgt tgtcatcatt
    49201 tttcgttcag aatcaaaagg aagctcgttt actcgtggat atttttcttc taattctgcc
    49261 tttgtatgat aattctcttc aacagccctt acgatggcta cttctgttgg attacctttg
    49321 ataacaaggt cgtcatcttc ttgctcgacc gtcacatctg tacatagtgc agccattttc
    49381 aatatttcca tcgcgctgtt cgtcattgaa tcttcgatat tcgttacttc atcttctttg
    49441 ctccataccc ggcggacgcg catttcattt tgtgtcagcg ttcctgtttt gtctgagcag
    49501 ataacattag cggttcctag cgtttcaact gctggcaact gtcggatgat cgcatgtttc
    49561 ctcgccatct tctgcacacc gtatgcaagt gtcaacgtaa caataacagt caaggtttcc
    49621 ggtacagctg caacagccaa ggaaatcgaa gtcatgaaca tctcaaggag tggttctcct
    49681 tgcagttcac caatcacaaa tactaaagcc gcagccgcta aagcgatcat actgattcgt
    49741 ttgcctagct gattcaatcg gacctgtaaa ggtgtttttt gcatagtatt ttcgttcaaa
    49801 agatccgcga tcttacccat ttctgtagcc atgccaatgg cagtgacgat cgctttccca
    49861 cgacctgcag caaccgtaca tcctttaaat accatattaa gttggtcacc taatgactca
    49921 tcttcttcag caataaatgc tgcatctttt tcaactgctt cactttctcc agtcaacgcc
    49981 gattcttcta cacgtaattg tgatgcttcg atcaaacggg catcggcaga aatagcatca
    50041 ccggactcta aaacaagaat atcacccact accagttgct ctgactcaac agtggtcact
    50101 ttgccgtctc gtatgacagt tgccgtttgt ttattcatat cttgcaagga ttccagtgct
    50161 ttttctgcgt ttccttcttg gacaatcgcc aataccgagt tgatcacaac gatagcgatg
    50221 atcagcagtc cttcaaataa atccccatgt tctgtagcaa atgcggtata aaaggaaatc
    50281 accgctgcta caagaaggat gatcgttgta aaatcggaca agcttcgaaa gaattttttg
    50341 atcatcgatt ctttcggcgc ctcatcgaat ttattcaatc cctgcttttt tcgccgttca
    50401 tccacttctt gtgaagacaa cccagtatct ggatctgctt ctgttacctt ctttacttct
    50461 tctattgtct gcttgtattc ttccatccta ttcctccttt aaaatcttcg tacaaaaaaa
    50521 ggtacttatt ttactataac atcctttttt tatttacttc aaataaaggg cttatcgatt
    50581 atttgttaag aaagcgtaaa atttaaagtg cttatatttg caaacgctac caaaggatgc
    50641 tattatatag atgtaaggaa ggaggatacc atcaaataga cagaagaatt tctcgataga
    50701 acagtgtaag caaacaaagt tgttagaagt acaggtttca cccagacatg cgtgtagagt
    50761 acaaacctat aaatagtgaa tgcgtatgga tgtttggatc acgaagtatc cgaaacaaga
    50821 agtaatgcga tacgtaacaa ttgaataacg taaacgtctg aaaattgaat aggaacaaga
    50881 gatgtttcaa atgttgaaga tgtaacgaaa acaaaatttt tgtttaacat gaagaaattc
    50941 aacaccgtgc tttgcatgta tgatggaaag ttacaatcat ttctgtttat ttgaatcctt
    51001 ccgaggtaca agaaagccga gcttatcgag agctcggctt tttctttgtc ataaaatctt
    51061 tgtaaagctt ttttgttatt caaaactagc ggcttttcat aaccttattt cacgaacatc
    51121 gcatctccaa aactaaagaa acgatagcgc tcttcaatcg catgctggta agcagataaa
    51181 gtcaattctc ttcctgcaaa ggcactaact aacatgacta aagtcgattt tggcaaatgg
    51241 aaattagttg agaaagcttc taccactttg aattcatagc caggcgtaat gaaaatatca
    51301 gtccatccgc tgtctgcttt gatttctcca ttaaatttcg ttccaatcgt ttctaatgtt
    51361 cgaattgaag ttgttccgac agccacgatt ttcccgccat ttttacgtac ttggttcaat
    51421 cgctcagccg cttcttccgt caaacggtag aattcactat gcatatggtg ttcttcaatt
    51481 ttatctacgc tgacaggtcg gaatgtacct aaccctacat gtagtgtcag atagactaat
    51541 tcaacaccct ttgcttcgat ctcatcaagt aattctttcg taaaatgcaa tccagctgtt
    51601 ggcgctgcag cagaaccatt ttctttcgca tagacagttt gatagcgatc tgggtcttcc
    51661 agacgttctt tgatatatgg aggcaatggc atttctccca atgattcaag aatctctaga
    51721 aaaattcctt catactcaaa gtcaatgatc cgtccgccgt gttccaattc ttctttcact
    51781 actgcttgca atctgccatc accaaaagag attcttgtcc caactttggc acgtttcgca
    51841 ggtttgatca atgtctccca cgtatctcct tgtgtattcg ttagaagaag gacttctaaa
    51901 tgcgcaccag tatctggttt ttctccatat aaacgagcag gcagaactcg tgtattattc
    51961 ataactagcg catcaccagg ctgtaactct tcaatgattt catggaaatg tttatcttcc
    52021 atctctccag ttttccgatc caaaacaagt aaacgagaat gatcgcggtc ttttaatggt
    52081 gtttgtgcga ttaattcttc cggcaagtca aaatcaaaat cttctgttgt taacatatcg
    52141 tcactcactt tctatcatgt gcttcatcat tctatcatgt ttttcgttct gttggcaaaa
    52201 tcagcacttt ttcacttcta ttttttgttt tcctaaataa aaaaactacc ctatttgtat
    52261 tttttcattg ttttaggcat actagtaata gatagttctt cattgaaaat agaaaaagag
    52321 gtggcaccat gattgaattt caaaatgtgt caaaaattta taaaggtgga aaagtcgctg
    52381 tagaggacgt caatctttca tttgaaaagg gtgagttcat ttgttttatc ggtacgagcg
    52441 gaagcggaaa aacgacgacg atgcggatga tcaaccgaat gactgatcca acacaaggga
    52501 aaattttgat tgatggaaaa tccatccaag aaattgatcc agtggaattg cgacgtcaga
    52561 tcggctatgt tatccaaagt attggattga tgcctcacat gacgatccgt gaaaatatca
    52621 ctcttgtcca aaaattgttg aaagtcagtc aagaagaacg gaataaaaca gctgaaaaaa
    52681 tgattgatct tgtggaattg ccccgtgaga tgttagatcg ctacccacat gaattatctg
    52741 gtggtcagca gcagcgtatt ggagtcgttc gtgcccttgc agcgaatcaa gatatcatct
    52801 tgatggacga gccattcggt gcgcttgatc caatcactcg tgattccttg caagaccttg
    52861 tcaaagattt acaagagcgt ttgggaaaaa cgatcgtatt tgtaacccat gacatggatg
    52921 aagcgattaa actagcaagc cgtatcgcca tcatgagtga aggccgtgtg atccaatttg
    52981 atacaccaga aaatatttta cgtcatcctg caaacgattt cgtagaagag ttgattggag
    53041 aagatcgcct actacaagcc aagccaaatg cgacaagagt cggcgaagtt atgctaaata
    53101 cagcaatcac gattacaccg gaaaaatcat tacaagaagc aatcaaactg atgagggaaa
    53161 aacgtgtaga tacgttgtta gttaccgata attcgaatgt attaaaagga tttatcgatg
    53221 tagaaacgtt gaataaaaaa cgaggaaaag tatccagtgt cggcgacatt ttgaataaac
    53281 atgtttttta cgtaaaagaa tccgcctatc ttcgtgatac cttgcaacgc attttaaaac
    53341 gcgggctgaa atacgtgccg gtcgttgatg aacagaacaa agtcgtaggt atcctgactc
    53401 gtgcatcatt agtggatatc gtctacgatg tgatttgggg agaagatccc gcaactactg
    53461 atgttgcaga gtcagctact cctgaagaat ctaaggaggt ctgacctatg cagcagtttt
    53521 ttcatcagca cggttcagaa attctctcaa aaggttttga acatctttat atttcaggac
    53581 ttgctttgat cattggtatc atcattgctg taccgcttgg tgtcttactg acacgttttc
    53641 caaaagctgc cacgattgtg attggcttaa ccagtgcctt gcagacaatc ccttctcttg
    53701 ctttattggc attgatgatc ccgctatttg gcgtaggtaa attacctgcg attatcgcac
    53761 tctttattta ttcattattg ccgattttac gtaatacgta cattgggatg aaaaatgtcg
    53821 attggaatta tcgggatgtg gcaaaaggca tggggatgac tgagttccaa tccatttttt
    53881 ccgttgaatt gcccattgct atgccaacga tcatggctgg tattcgttta gctgccgttt
    53941 acgtgattgc atgggctaca cttgcctctt atatcggcgc tggtggttta ggcgatttga
    54001 tttttagtgg actgaataat taccaaccag atctcatttt ggcaggtacg atccctgtaa
    54061 caattttagc actattggct gattggcttc taggtctctt ggaacaccgg ctgacaccga
    54121 tcgcacttag agaggagaat gaagaatgaa acgtatacta aaaatgacca tggttctttt
    54181 ctctcttctt atacttgcga gttgttcctt ccctggtctt gccagcaata cagatgaaga
    54241 caccatttcg atcacaggtg gaatcacttc agaagcacag atcttagcaa gtctagttgc
    54301 cggaatggtt gaacattata cagataaaaa taccgcaatc atcaacaatc tggctactac
    54361 aactatcaac catcaagcga tgatgaacgg agatgcttca atttcagcgg ctcgctacac
    54421 aggaacagat ttaacgacta cattgaacct tcctcctgaa aaagatccga aaaaagcgtt
    54481 tgctaccgtg aaagatgaat ttgagaaaag atacggtcaa acgtggttcc cgtcctatag
    54541 ttttgaaaat acgtatgtct ttcttgttcg aaaagacacc gcacaaaaat accatctatc
    54601 taaagtcagc gatctgaaaa atgtagcgga tgaattagta gctggtgtag atacttcttg
    54661 gatcaatcgt aaaggagacg gttatgacgg cttccaagaa acttatggct tctccttcaa
    54721 ttcgatatta cctatgcaga ttggacttgt ttatgacgca gtcgaagcag gaaaaatgga
    54781 tattgttctt ggctactcta cggatggacg gatcgccagt tatgatctag tcatgttgga
    54841 agatgatcgt caattcttcc caccatatga tgctgctcca gttgtagaca acaagatatt
    54901 agctgatacg cctcatttaa aagaagcctt aaataagtta ggtcatacca tcagtacgga
    54961 aaaaatgcag gaattgaact acgaagcaga taataatcta gtggaaccat cagtagtagc
    55021 acaacgtttc ttacaagaaa accactattt tgaagggaag tgaagcaatt ggataaaatg
    55081 aatgtctttc aacaattttt ctattatttc caggaaaatg gctcctatat ctttgcacaa
    55141 tttatccgtc acttcctgat ttctatctat ggtgtcctct ttgcagcagt tgtcgggatt
    55201 ccggttggga tcatgatttc taggagacgt aaattagcaa actgggtgat tcgtttggcg
    55261 aatatcatcc agacgatccc ttctctagcc atgatctcca ttttaatcat tggattaggc
    55321 ctgggagtca atgtcgtgat tgttactgta tttttgtatt ccctcttacc gatcatcaag
    55381 aatacgtata ccgggatgat ccaagtagac aaaaacatcc ttgatgtcgg caaaggcatg
    55441 gggatgactg ctagacaacg actattcatg gtagagttac cactctctgt ttctgttatc
    55501 atggcaggca taagaaacgc gttagttgtt gccatcggga taaccgcgat cggtgcattc
    55561 gtcggtgctg gtggtcttgg agatatcatt atccgaggaa ccaatgcaac agagggcaca
    55621 tcgattattt tagcaggtgc attgccaact gcattaatgg cgatcatcac ggactggctt
    55681 ttaggtattt tggaaagacg gctagatcca gccagccgta catcacgctg atgttattgt
    55741 aaaaaacaaa agcttctgcg accatttgtt ggtcgcaaag gcttttttag ttctgtcatt
    55801 tttaaggcaa taatccactc tgattcttcc ctccttatgg gcaaagagtt gcttttctta
    55861 gctatttatc cattccgtat actccaactt catactgcca acgggttcat atctgcatcc
    55921 accgactaag tttttttctt atccgctaag gcattttgcc aatccatttt cccatcactc
    55981 gtcatggaat tcataccaca tgatctctaa atactcgtct gcttgttctt tgaattgggc
    56041 atcaattctt acatcctttg gcgtggcttt catttaagcc ttttccatca gtcctcgatt
    56101 gttcgatgcc ttcagctgca tcatcaaaac tggtgactgc cgtatcggta acttcgatca
    56161 tcttttatac aatcgggaac ttgccatcct catccttggc taaaaacata tctagccatt
    56221 ccagcttctc gccatgggag gtttgcggtt cctaaaaccg gtacacgatt cttatggact
    56281 gcatccgtcg caactagact tggcgatacg atgatccttc accagaagag cacccccgta
    56341 aaccaattga tcgatatatt gccaataaga aaagacattg gcgtaaaaga tatcgatccc
    56401 tcgtgatgca ttgccgttga tactgctatt catggccgaa agcgccacga ctttaacttc
    56461 ttccgtttga gtgacattca tgttcggcaa tgtcgctttg gatacccgct ctgctaaagg
    56521 aacgacactg gtattgtatt tcgtatctgt atcttttcca aaagaccatg ccaacgaatc
    56581 ctctgggaac caataagacg actccggttg attgtccatt gcttttttca acatactttt
    56641 ggctgtttct cgataaacga catttccaat tgtcttcgcc tcactttggc gataatcgat
    56701 ggtcgttgcc actgccaaca ctaacaacga tgctccaatt ttactgattt tccttgtcac
    56761 acttcttcct ccttgtttta cataaacccg tcaacattcc attcctaaac tcaaacaatg
    56821 acccttcaaa ggtggagata taggaacaaa ttaaagaaat catgcaataa atccaagaag
    56881 gttggtttta gaacaaaaaa agagtctcct ttttggggag actctttgtt aactatctaa
    56941 aaaggttggc tcttctcact tcactcataa tgtgtccagg cagaataaat ttctacaact
    57001 ttattttcct catcaacttt gtaaaccact cgatgctgtc tattcagcct gcgtgagtat
    57061 ctgccttcat gtgtaggtct cagcttttca aaagactgcg tgggcatata tggatcttcc
    57121 ttcaatgtct gaatcacttc ttcaaattgt ttctttaaat tcgtttgctt gatttttctt
    57181 aaatccactt tcgcagagtt tttgattgcg actgtatagt tactcatcaa agagcttccc
    57241 aatcaatatc atcgatattc gtaaagctac tgtcgtcttt ttcgcggtct cgtactttat
    57301 ctaaagtacc tgtttgctca agaaaaaggg tttcttgaat cgctctccag tcttccagcc
    57361 caatcaatac agcattgttt ccactacgat cactaataat ctcgatttca gtatgatttt
    57421 catttacctc tttcaataac tgataaaaat ttttacgagc agtgctagga ttcatcgttg
    57481 tattagccat tgtctctcct cctttttctg atataattat agcgtacttg attaagtacg
    57541 tcaaaaaaat acaataaagc acttaaattc agcaaacttt tcctcttttt tacatagaga
    57601 aaaagacccc tttttaggga ggatctttgt ccacgctcac ttcttactcc tttacgacta
    57661 gcggtagcca aacgtaaagt aattggtaac aacgtatcat ctttagcaaa ggtcgaatcc
    57721 aaagcctgtg agtctatgca acaacaccaa tacacgaagg ttcctcgttg cagtgtgact
    57781 tgattgatat cttgaataac ctgaggatac gcacgaaaga tttgtaacgg ttattcaaaa
    57841 ctgattttgg ccgtcaagtc ttctactgcc tcaaaaatga ttgcctcttt cgtctcctgt
    57901 cattcatgtt cactatcgat ttgatacttg cttagaccgt tgggtttgtg aatcaccaat
    57961 taaaaatggc actgagttat ggtaacaaaa aatggtcact tgacgaggct gagattccta
    58021 cttatgaaga cacatggcac ttaagagtcg aggtaaagga agaagctgaa aatataggag
    58081 gctgtacatt atttggcaaa ggattcggaa attatgatca agacatcaaa atcaaaatgt
    58141 tttacagcta aataggaaga ataataacat ttcatacgct gttcccatct ttaatggctt
    58201 atagagggca cctttagctg agaataagac aaaacagacc ctctagcttc aattaagagc
    58261 tagagggtct gtttttgatt ttaaaacttg gtttatttct tcaaatggta gctataggtg
    58321 ctgacaacga tattttcacg ccaagacaat cgcaatctta accgcaaact tgtttggtta
    58381 tggagaatat tctgccagcg tctgtttggt acaaattgag gaatcaacac agtagttgta
    58441 tagttttgtt tcgctgcatt tttacttacg atatctacat aacggataat tggattttca
    58501 atcgagcgat aagaagagtg gacgattgaa aaacggacat ctgggaaatg ctttttaaat
    58561 tctgcttcga tttctttttc tttttcgaca tcttcgtcta gcgaaacatg catcgcaacg
    58621 acataatcac cgatcgaacg tgcgtaattc aacgcaccga tatttacccg tgtcacattc
    58681 ccgactaata caagaacggt attcccgtca taatcatgta gttttgcatc attttctaaa
    58741 cgaagctgtt ctgctacttt tttataatga tcatggatct tataaaaaat gaacataacg
    58801 attggcataa tgatgaagaa aggccaaatg tcccctaacc gatagacaaa caaaatcgca
    58861 atgattgcat atgagatgaa cgcacccgta atattggcaa tcgatttgct taaccatctt
    58921 tttccttctt ttttccattt gacgaccatc cctgtttgag ataaagcaaa tggaatgaac
    58981 acgccgatag agtataacgg aatcaagcgt tctgttgagc catggaaaat aaacagcaat
    59041 acgatcgaac ctagcgctag tgtgataatc ccattggaat agcctagtcg atccccacga
    59101 tcttgataca tgtgaggcat gaatttatct tttgccagat tgtatgcaag aactggaaaa
    59161 gcagaaaaac cggtgttagc agcaactgct aaaatcagcg ctgtagcaaa ttgaaggacg
    59221 taatacaaaa taccatgtcc aaagacagct ttaccaattt gagacaaaac agtgacttct
    59281 ttttcaggaa cgatcccata ccaatagttg ataaatgtga tccccacgaa gaagaaacct
    59341 aagatcaatg ccatcatcgt caatgtagca gcggcatttt ttgctcttgg cttcttaaag
    59401 aatggtacag cattactaat cgcctccacc ccagttaaag aggaagaacc agaagaaaat
    59461 gctcgtaaaa tcaaagcgat agaaacaccc ggcacagccg ctcctggaag tgcagtagct
    59521 tgcaatggca cagcacctgt cacgatatta tataaaccaa caacgatcag taacgagatc
    59581 acaaggataa atgtgtacac cggaaataat aggaacgatg cagattccct cagcccacga
    59641 agattcagca tcatcagtag caaaacgatt gtcacagaaa tagcgacttg atgaccgtag
    59701 agtgctggca ccgctgatgt gatcgcttca gcacctgctg agacagatac tgctactgtc
    59761 aacatgtagt cgatcaataa agagccaccg gaaatcaagc cagcattctt tccaagattc
    59821 tcactgctga cgacatatgc tcccccgcca tgaggataag catggatgat ttgacgatat
    59881 gatagcgtta atgaaatcaa taaaataata acaaaagcgg caatgggtag cgaataccag
    59941 atggctgcag cagacaaagc gactaaaacg acaacgattt gttccgtacc atatgcaata
    60001 gatgataacg catcagacga caataatgcc aaagcagcaa atcgggttaa tttgtgctca
    60061 tcattttcag cagattttaa aggcttacct actaacaacc tttttaagta atccaatttc
    60121 taaactcctt tacacacaat tttacttcaa gttttatagt cgaaaattta tagtaaacaa
    60181 gatgttatag tacgctcact gaccttaaaa gtcaataaac tttaagaaaa taattggaaa
    60241 aaaacagaaa aatatcaagc gctttttcaa acgctttaat acagcaaaaa tctaacattt
    60301 ttttatgggc tttttctttg aattctataa taaaaggata gaacttgact tagaaaatca
    60361 agttctatcc tttttgatat cttaactttt ggaagagaga tgtaaggctg ctttctaccc
    60421 atcattctta ctactcgaag catagcgcag ttgtcacaac ctcttgataa acggtgttta
    60481 aaagcttgca tctgcggtaa taagcccaac caaattaaaa acataagaag ctgtttttat
    60541 ttggtcgttc ttattacttg atgcagagca gcttttttac aacctcttgg tacacggtgt
    60601 tcaatcagct gaccctcggt attagctcaa aaaaacggca aaatatgagg aactattttt
    60661 ccattttttt ctctaatact caggtcaaaa cactgatttc acaacctctt tttttaatga
    60721 aaaatatggc tctcatgcgc cgcttctttg aatttcgtca ttttttcttc gatgaacgga
    60781 tagattgccg ttcctacgat tccaaagaca acaaacaaac cgatcatgat ccagattgct
    60841 ttcgtagcat ttggccaata aattcctcct gcagattccc gtaacaagtt taccgcatga
    60901 gtaaatggca agaacggatt gatcatttgg aagaatttcc ctgagacttg gatcggatag
    60961 ttcccgcctc cgccagagat cgacagtact aagatgataa tagcgatccc tttaccgaca
    61021 ttatcgaata atgcagccaa gacatagacg atcatcatga acgctaaggc gatcaagaca
    61081 gcaaatgaca cgctgtagac cggattttgg acatctactc ctagtaagaa aatattccct
    61141 aatgtaacga tcaagctttg cgcaatcgcc attgtcaaaa atgtcagcat acgagcaacg
    61201 aattgttctc gtttcgtaaa attgtttcgg tctttctttc ctaaatagta ttctgtcgta
    61261 gcaacacttg aaagaagaac agcgccgacc cacagacata gtgcagtata aaacggggtg
    61321 ctagctgaac cgttatttgc gattggataa agcgcattgg tttgtagctc aacaggttgt
    61381 gtaaagaagt cactttcttt tgttgcgtct agtttcaata atttgatgac ttcgcctaga
    61441 tcgacttctt gttcgccttt tcggatcgcg tctgctgctt tttggatacc agctttgata
    61501 tttggccagt cattgttgat caagtccgca gcagcgttca cagctgtttc gacttctggc
    61561 attttttcat ttactgttgt caatgtaccg gtgatttcat tttttagtgc tggccaatca
    61621 ttttggataa aatcagcggc caatcctaat ttttgctgaa tgatcggtaa ttcattgttg
    61681 tataggtctg ccccttcatt gatgccattg acgatggtat ccatatttcc attcagcatt
    61741 gtattggcat catggatttc ttgtccaatt gcaggcattt ctttttgata tttttctaaa
    61801 attgccactg cattcgttac agttgctttc gttgagctga gaagcgaatc aaagtcgatc
    61861 tggtccgctt tgctcagtgc gccttgtgca gtcccaatcg tatcgatgac ttggtctagt
    61921 agagaagtga cagtggaact gatttgacct gtattgatac cagcaatgat gccattgata
    61981 ttattaacaa cggcatcaat ttgatctagc aattcatcaa tagccttcgt gtcttcattt
    62041 tgaacagctg tgttcaaagc agataggcgg ttttgcagat tgcttagcaa gggttttaat
    62101 tgatttagct gatcaataat tggctgtaat ttcgtatttc cagcacttgt ttgcaattta
    62161 gtcaggaact cgaccagttt atcgattgca ttttgttgtt gagatattcc gtcaataaag
    62221 ccgttcaata cattgctgat gtttttcttt tcatcatcag tcagcttacc atcttcaata
    62281 gctgttctta cagtatctat taacgaacct gtcgttgttg ccacttgtcc aattgacttc
    62341 aatgtaacat ctacactgtt tgtgatgctt ggtatcgcat ctttcagctg agaggcacct
    62401 gattttgttt ggtttgctag atcacttgcc tgattttcta aatttttcac atctggcaag
    62461 atatcttgta cttgttggat gatcgtcaag ccttgttttg cttcatcgat tccttggttc
    62521 attgtctctt ggatcgaagc aaaatcgccg tcgatctctg ctagttgctt accggcattt
    62581 tggatctctg ggattttttc ttgcaaatca aggatgattt ttgcttgatc tttcaactca
    62641 ggcattttgt cattcaatgc aacgactttt tcacccatct catctacttt agggatgtaa
    62701 tccacgaatt catttgcttt attcagtttt tccttgattt caggtagttg actttgtaat
    62761 tcgaggactt gttttgtgta gccgtcgatc gtgtccaaat tttcatctgt tgataaaatc
    62821 atatctttaa ctttattgat acttactagg ttcgtatcga tgtcgtaacc tatctcattg
    62881 aatactttca ataaagtcga actggctgtt ttgataaatt catttgtgat ttgcgattgg
    62941 atcgaacttg ctcctttatc ggtgattttc ggtgcaatcg cattgatttt ttcatttacc
    63001 gtatattcga tttttggttt cttgatatca ccactagtaa aactcagcag atcttctgag
    63061 aaatcctttg gcaagtaaat acctgcgtaa tactttccgg aacggactcc gtcttctaat
    63121 tgttcttttg aatcaacgaa ttgccatcct aattgtttat ttttatgaag cgattcgatg
    63181 acttgctccc caatggccac ttctttacct tgaaactctg ctggcttgtc tgcactgtaa
    63241 acagcaattg gcagctctcc agtatttcca tatggatccc ataatgcttt gatgttaaac
    63301 cacgcatata gcgaagggat gatcatgatc gcgatgatca gaagtgttgc aatcgggttt
    63361 ttgaaaatcc gtttccagtc aagcaaatat aatcgaagcg tatttttgat tgactgcata
    63421 gttctccccc ttcttctttt ttcagctgaa ttactttacc atgtatttca tacttttttc
    63481 aatcggcttt tttcaaaaaa gtcgaatttt tggacatatc acggcaattg tctcattgta
    63541 atctcttaca tattgagaaa taattaagga ttacagcctt tactttatca tgaaataaaa
    63601 gggaaagata attttatgcc aaagttttta tctattatac gtatacgcaa aaaagctaaa
    63661 acattttttg tctttgcccc tacaaaaatg tttcagcttt tttcgttttt tattcctgta
    63721 tttcttattt ttcgaatgac aggatgattt tcccagcagg aggatgtcct tcaactagct
    63781 gatgtgcttg gatgacatgc ttaagtgaag cagacagatt cattgaaata aaaacatgaa
    63841 aggctccttt ttggtaggct ttgattatgc cagcaaaggc ttctgcatct agatattcct
    63901 ttcttggaac aaacgattca taaaagcctt cctttttttg ccgcaaatct agatctggga
    63961 ggtcatttaa tgcaacatac ctgccgcctg gtttcatgat ctggatgccg gtttctcctt
    64021 tgatacttcc tttcgtcgca tcgattacaa ggtctgcctg atcagcaaat tgcagacctg
    64081 gatttgtttt atcataagca gcaaatgctg aagctcctaa tttttttacc ttttcctcat
    64141 ttttactgga tgcactggtt aagattcgga ttcccttttc atggagaagc tggatcagac
    64201 ttgacccgac cgcacctgat gctcctagta tcattacagt atctgtcggc tggatttccg
    64261 tcaaatggtt gattagatta taagccgtaa ttcctggcgt gaccattccg gctgcttctt
    64321 cccaactcat tttatctgga atttttgcta cttttgctga tggcaacacg acttcttctc
    64381 cgtaagtccc gccgactgca tggacagcta ctcgatcacc tacatgaaca gttgtgacat
    64441 ctgaaccaat ctctgtcaca ataccagcgc catcattacc tggtacataa gggaatttca
    64501 atgttcgtat ctctttcatt tctcctaaac gcaaggcaac atcataagga ttcacactga
    64561 atgcttttat ttctacacga acatgtccag aaccgacttc tctgggatga gcatcgattt
    64621 cttcaaaaac atcttgtgct tctccgtaac cgttaattgc aaatcttcgc atggtcacca
    64681 tctccctttt tctttaagtt tacgtttatg cctttatttt gacaaaaaaa atgtcttttc
    64741 gttttggcgc atgattcaaa acaaaatagt tgtctttttt cgcgtaacgt gttaaattat
    64801 ttatctaaaa gcgtaaagat tacgatttac gctaataaaa aataattgga ggaatttgtt
    64861 gatggctaaa aaatcaaaga ttgccaaagc aaaaaaacag caagaaacga ttgaacgcta
    64921 tgctgcttta cgccaggaat taaaagcgca aaaagattac gaaggcttgc gtaaacttcc
    64981 tttagatgct cgtccagaac gattgaaaaa tcgtgattta atcgatggac gccctcgcgg
    65041 atacatgcgt aaattcggga tgtcccgtat aaaattccgt gaattagcac ataaaggttt
    65101 gattccagga gtaaaaaaag ccagctggta atccaagtct ggctgtaatg taaaggagga
    65161 gggcgcatgg accactcctt ggatcatcaa aaaagatacg ttcgcttctt ctagcagaaa
    65221 tgctggtact agaagcagac gtatcttttt ttacgcacag ctggtccttt tttatatgta
    65281 aaggctgcat ggttacttcg ctatatttat ttagtaacag gagtcagtgc ttcgataccc
    65341 acactaattt tcaatgctcg gtcaacttct gccataatgg gtcgatccaa atggcagacc
    65401 ttttctttca atcttgattt atcgatcgtt ctgatctgct ccaacaggat aacggagtct
    65461 ctttctattc ctgttccagt agctttgatc ccaatgtgag tcggaagctt aggtttagcc
    65521 atttttgccg ttatggccgc aacaatgatc gtcgggctaa aatggttacc tagattattt
    65581 tgaataacca aaactgggcg tgttccgcct tgctccgatc ccacgactgg agaaagatca
    65641 gcaaaataaa tatctcctct ttttaccata ggatcctcct tattcttgat attctcttgg
    65701 tatccgctgt cctaatccgc aagccacttc atagtggatc gtacctaatt gatctgctat
    65761 atcctgcata gtgatttctt tgtctgcatt tttgccgata agcgtcactt ttgttccgac
    65821 aggaaattct tgaggcaatc ggatcatcag ttgatccata catacacgcc caatcgtttc
    65881 acagtagttc ccttctacca atagagaaaa accctgcatc tttcgtggcc agccatctgc
    65941 ataaccgatc ggtatcgttc cgatccactc tgcttcagga gtgatatatg tttctccata
    66001 gccgattcct tcacctgctg ggagtttttt gacttgaatc aattcagaaa ccagctcaag
    66061 tgctggctgc aatggataaa cttccggtag tgcgtgccca gagggattaa gtccgtacat
    66121 tgctactcca taacgaatca tattgccgat tgtttcatca tgccataaag ccgttgcact
    66181 attgctgaca tgtacatatc gaggaagttc gggaagtttt ttcagcactt ctataaagcg
    66241 ttctttttgc agattccaat atgtatcatc tgcctgatct gctgtagaaa aatgggtaaa
    66301 taaaccttcc cattctaata cacgactttc tttgatgaat gcagctgcct cttttacttc
    66361 ttcaggtgta caaaatccga tacgacccat cccagtgtct gcttttagat gaatcgaaag
    66421 aggcgtctct agcttacttt tctctaaaac agcagctgct gcttgcaacc attcccgtgt
    66481 acctgcagtt actgataaat catgagcaac agctacagtc agtgcgtcgt aaggaaccat
    66541 attcaagata aggatgggct gagtaaatcc agcttctctc aactcgactc cttcatctaa
    66601 atttgaaaca caaaagcccg aagctccacc tgcaactgct gcctcagctg tttcaatagc
    66661 tccatgaccg tatccgttcg cttttactac tgcaaacaat tcttttcctt gcggaagtct
    66721 tgcaacttca tttgctacat tttcagttat agctttttta tgtatcactg ctttcgttgg
    66781 gcggtgccaa gcgacaacca tcgtttttcc ttctttctag tcttccaaaa taatttgtgc
    66841 aaaagctgtt tcatttgtat gagtaatact gacccataca ttgccttcat gaggtgaacg
    66901 cgtcacaaca ggctgaccat tttcattttt taaaatctcg acatcttgaa aggtaacttt
    66961 tccgatccca gttccccaag ctttagagaa agcctctttg caagcgtaac gcccgcctaa
    67021 aaattctact tggcgatgaa aaggcaagga ctggaatagt ttcatttcat cagaggtcaa
    67081 gattcgtgca atgaattttg gtttttcttc gatcagccga gtgatcctag gaagttcgac
    67141 tgcatcgatc ccaattcctt ttatcatatg cttttctctt ttcaataaat ttagaacact
    67201 ctcattctac caaattataa ccattttgcc acaaataagt ccacaaataa caaaaatgaa
    67261 agtttctctt aaaaaagaga aactttcatt ttatgtttaa tcgttatttg aacggattac
    67321 aaatccgcgt tttttatcat tgtgacgttt accgccatct ttttggctgt tattattttt
    67381 gctataaccg ccttttgatt tgtttccacg ataattaccg ccgtcacgac gattacggtt
    67441 gtttccgcca ccacgtttgc catttttatt gtatcctttt ttctgcattg gcaatgggcg
    67501 ttctggtgtg atcttcactg gcactgcatc agctggatct tttgctgtcg tttttagcaa
    67561 aagtgcaact aaatcttgtg cagaatattc ttctaataat ttatctgctg tttgcaggta
    67621 tttatctaga ccattttctg caagttttgt ttcgatttgt tcaactgcag cacctaattg
    67681 acctttgaat gcttcttttt cggttggtgg acgtaaagtc gtcatccgtt ttttcgtcaa
    67741 gttttcaatc acatgcaagt agtccatttc atttggtgta acgaaagtca cagacatacc
    67801 gccttttccg gcacggcctg tacgtccgat acggtgaacg tagctttctg gatcttgagg
    67861 gatatcatag ttgtacacat gagtgacacc tgaaatatct aatccacgtg cagcaacgtc
    67921 tgtcgctaca aggatatcta aatgaccgct cttaaatgaa cgcaatacgc tcattcgttt
    67981 ttgttgagac aaatcgccat ggattccttc tgcacggtaa ccgcgtgctt ctaatccgcg
    68041 tgccaattcg tctacacggc gttttgtacg tccgaagacg attgttaatt caggtgtttg
    68101 aacatcaaac aagcgagtca tgatatcgaa tttttcgtat tcttttgcgc ggacatagta
    68161 ttgatcgatc aagtcagctg tcatttcttt cgctttgatc ttcacatgat gtggattttt
    68221 catgaattta acgccaatat tcttgatagc tggcggcatc gttgctgaga aaagtaatgt
    68281 ttgtctttga tcaggaactt gtgaaatgat tttttcgata tcttccaaga agcccatatt
    68341 caacatttca tctgcttcat ccaaaactaa tgtttgaacg gttccaagtt tcaatgtgtg
    68401 gcggttaatg tggtcaagca tacgtcctgg tgtacccaca acgatatgtg gacgatcttt
    68461 caagccacgg atctgacggc caatatctgc tccgccgtaa acggcttgta cacgtacttt
    68521 tttgtcgcgc cctaaacgat ataattcttc ttgtgtttgg atagctaatt cacgtgttgg
    68581 tgcgataact aaaccttgta attcgtgacg atctggatcg attttttcta acattggtaa
    68641 tccaaatgca gctgttttcc ctgtacctgt ctgtgcttgt ccaataacgt cttttccagc
    68701 taatgctagt ggaatcgttt ctgcttggat aggcgttgct tcttcaaaac cagcgcgttc
    68761 gactgatttc aacaattctg gtgataattc tagttcttta aatttcaaat gaatcctcct
    68821 atatggttgt taactgagga tgtagctttt ttgctacccc gtcgatttgt tcggtcaaag
    68881 tgtattgttt ctttttgaca gtggccacgc acgtttttat ccattcttag cccctgtggc
    68941 accaccgaaa aatcactttg cgaagtttag gcattagaaa agccaaacgg gtcgcgttca
    69001 gctttatcat tattatgaca tctggcttca acaagttgtt tctatggcaa aaccagtcca
    69061 atttctcttc atctttcggc aataggttat tctaacatag tttttcgttt tctgcaagtt
    69121 tacagatttt tatttcattt gctgaagttg ttctaccact tcaaataagc ccatgctgtt
    69181 gctgcctttt agcataatac tatctgttgc ttcaagattt tgtttgatag catcaatcaa
    69241 tttattcttt tctttttcaa aatagaacac aggtagttgg gggtattttt ggttcaattc
    69301 ttcttttagt gcatgcattt gttccccata aaggaaaatc atggcgaatt tctcaggatc
    69361 gatatgttca ctcatttgcg catgcatatt taaagactct ttccctaatt ccagcatatc
    69421 tgctaacaca gcgattctgc gtccttttgt tggcagattt ttaaaagtat ctaataccag
    69481 tcccatggct gttggatttg cattgtagac atcgctcaaa atagctgcac catttcctgc
    69541 cgttagccat tcggttctgt tttgagtgat agaaacatgg gcgagccctt ggcgtatctc
    69601 aggtatggac agtccaaaga agcgcccgat cgtatacgca atcaaagcat tcgttacatt
    69661 ataacttcca ggcagcggga tcgtaaatgt ttctccttct actacaaaat cggtttgtgc
    69721 ttttcctttt gctgtcactt ccgcatgaac atcgccattt ccaataccga atgttgtgac
    69781 tgtttgtact aatgttgccg ttaaaggtgt cagcaacggt tcatctgcgg gcacaacgag
    69841 taatccgtct gatacaagtc cgtcagtgat ttccattttg gctttagcga ttccttctcg
    69901 cgacccaaga ttttctatgt gtgcttcacc gatcattgtg attgctgcag cttttggttg
    69961 agccataagt gaaagttccg tgatttcatt ggcgtgatcc atgcccattt ccaaaacgat
    70021 cttttctgta tcttggggca tgtgcaaaat cgtgtaagga agaccaatat tattgttgta
    70081 atttccttgc gtcttatatg ttttgtattt ttcagacaag acagacgcgg ttagatcttt
    70141 cgtggtggtt ttaccattgc ttcctgtaat tgcaacgact tctgcgccta ctttttccaa
    70201 gtaataggtt gccaattgct gcatggcttt caaaggatct gctacaggaa taactggaaa
    70261 attttttgga gcttgttcaa caggcaagct ccaaaatgaa gcagatgctc cgtttgtgat
    70321 cgcttgctgg ataaattcat gtccatctcg cgtaccagca agaggaacga ataaacttcc
    70381 ttcggttatc ttccggctgt caaattcgac attggtaatc tttgtcagtg cagagcattc
    70441 gctgcccacg gcttgtgcaa tttcttgtat tgttagattc attgagatct ctcctaaaaa
    70501 aggttgtgaa aaaagcgttt ggcctaaacg gcgggttcgc atgactctca cttccaagta
    70561 aatttctcta ttcgtattta gaagctagaa tgaacgcggt tacgcaatca ctccagcctc
    70621 ttctttattt ctctttattc atttttttca aaaaaagatt gacgctgatg gtatcgattc
    70681 attcctaact ggatcagttc ttcaatcaaa tcaccgtatt tcaagcccat attttcccat
    70741 aagagtgggt acatactgaa ctccgtaaat cctggcatag agtttaattc attcaggaat
    70801 aattcatttt tatttgtcaa aaagaaatcg caccggctca atccgcttcc acctaacatc
    70861 gtgtaagcta acttcgcgta ctcttgcgct ttttgataaa cttcttctgg cacttcggct
    70921 ggaatctgca tttcgatttt attattgata tattttgctt cataatcata gaatgctacg
    70981 tcttttacga cttcaccagg caaagtcgtc cgaacgtctt catttcctaa tacagcaact
    71041 tcgatttcgc gcgcttcaat tccttgttca acgattgctc gagaatcata ctgataggct
    71101 gttgctaaag cattttgcag ctcttctcgg ttttctgctt ttgtaatgcc gacactagaa
    71161 cccatattcg ccggtttgac aaacatcgga taaagcaaag aaccttcaca ttgatcaaat
    71221 acttttttag gattttcttt ccattgattc ttaagtactg gtacataagg aacttgcggc
    71281 acaccagcag cttgtaaaat atacttggtc atgattttat ccatggcaca tgcactggtc
    71341 aatacgcctg cgccgacata aggcatattc aatgtctcta agaagccttg gatcgttcca
    71401 tcttccccgt ttggcccatg taaaactgga aaaacgatgg ctccttcttc tttgatttcg
    71461 cccggattga tcacttttcc tgtaaagcct tcctctgtct gtccacttgg gtcccatgaa
    71521 agatgcaaga catctttgct ggcaggtttt tctgttagta atggaccttt gacccattgt
    71581 ccttcttttg taataaatac gagttgaact tggtaataat tataataaat ggcatttaaa
    71641 actgaaaatg cggaaagaat ggacacttca tgctctgcgc tgcgtccgcc atatagtaaa
    71701 gtaatcttca aaagattgtc ctcctgtatt ctaaatcgtt cagtgattta ctctcatatt
    71761 ttagcacaaa acaaaaataa acgaataact tatttataaa aaaacgagcc agcttctaaa
    71821 agaacgagcg tcatttattt tttgtcagct agattatttg tcccgttttt tataaaaagt
    71881 tatgataaag aaaaggaggg atgatgatgg cgcaaacaaa tccacgcagc cgcttggcag
    71941 aaatcattcg agtgttcatc aattacaatg tagtgccaaa ctttgtacag caaaaaaatc
    72001 ccgaacaggt aaaaaaagcc tttgaagaac taggccccac cttcatcaag ataggacaga
    72061 tgctttctgt tcgagaagat ttgctttctt ctgccttcac tcaaacattc aaaacattac
    72121 aagatagtgt acctagcgac acattttcaa cggtcaaaaa gacgatcgaa acagaacttt
    72181 ctctttcatt atcagatata ttcgatgatt tttcaaaatc gccttttgcc tctgcttcta
    72241 tggggcaggc tcatcgtgcc aagctgaaga acggtgacgc ggtagtcgtt aagatccaac
    72301 accctaacat cgccgaagag atccgacttg atcttcaact atttgaacga gcgatccctt
    72361 tgatcaaata cattcctgaa actagcgtag ttgatctaaa aggggtactc caagaagtaa
    72421 aacgttcctt gatcaatgaa atggacttct taaaagaaag tcaaaatggc gaacaattct
    72481 atcaaaagaa caatggctgg aaagagatcc gcagccccaa gatttatgac gctttttgtt
    72541 cgaaaaaagt gatcgtgatg gaagaaatgt ctggtaaaaa cttgaatcat ttaatgaacg
    72601 ccgaaaacaa aactgaaact tttatcactg gaattcaaaa caagcagctg aaacaagaag
    72661 ttgcaaagct tttagttgag aactttatga aacaggtgtt tgatgatggt tttttccatg
    72721 ctgatcctca tccagggaat ctgctattcc atgtactaac aaaagaagaa cagacacaag
    72781 ctagccgaaa aactgaaaca gtccatgaaa aagagttcgg ttcctttgct tttcgagcct
    72841 ccacttctgc agaagaccct gttgcgccat ataccatcaa ctacatcgat tttggtatga
    72901 tggggcatct ttctgcagga cttaggcaaa aactcacaca agccgtttta gcgctgtata
    72961 cgaaagatgc ttatcgaatc gaaaaagcgg tccttcgact ttgtcagcaa gaaggctcgt
    73021 ttgatgaaag tcggttccac caagaactga caagttttct tgaacagtat tatgattctc
    73081 ctattgatga aatcaacttg caagaagtat tcacacatgt cgtgacgatt tgtcatcaaa
    73141 ataatctgca gttcgatcgt gatatcacgc ttttgctgaa agcatttggg acattagaag
    73201 gggtgatccg cgtcctcgat cctgaagttt ccctcatgga agtcgcttcg ccttttgctc
    73261 aacattattt tctcactcat ctggatgtag aagatacatt gaaacaaagc ggattagact
    73321 tattggaagg gatgaaggct gcgcctaaga tccctcaaca gctccaccat ctattagaaa
    73381 tgtggacttc gggacaagga aaagtcaatt tggaattgaa aaagcaagac aaattattga
    73441 gcaggatcga aagtatgatc aatcggcttg ttttcggtat gattttagct gcattgatcg
    73501 tagggtcctc cctgcttgtc caagcagcac ctgtagaaaa cgcagaggtc gtttccttat
    73561 tagggatatt tacgtatgct attgccgcat tcgtcattat ttttttggca atcgatgcat
    73621 tgatccaaat gtataagaag aggaaaaagt agaaaaaggt tgtgacagaa agaatcagct
    73681 tcaagaaata agaaggggtt ttacataaat tgtttctcaa atttttgtga aaattcggct
    73741 tatttttcga agaggctact tctgaaacac cgagaataaa aaatgtgaaa aagctgttct
    73801 gcacccagta ataagaacaa tcaaaaaggg aacatggaac acatttatcc tgtttccctg
    73861 ttcccttttt gatgtattcg agcataaata aaataccttc gttacctact atcttctgta
    73921 cttggtaaac cttagtcaat tgcctttttt aacgcttgac gaaaagacat atgatctttc
    73981 tccgtaaagg gttttggacc ctttgtcctt atgccagctt ttcttaactt tccactatga
    74041 taacgttgtt ctagaagcgt gccgatattc gcttcgtcaa attcttttcc agagtgatgg
    74101 aacactcgca cacccttcgg caatacaagt gaagctaaac cataatcttg cgtgatcaaa
    74161 aagtcattct tcttaaccat accgacgatt ttataatccg cactatcagc tccgcggtct
    74221 acgtagacga tttggacatg attagcgtat tctttggtcg tataatggtc cacactggtc
    74281 acgataacca cgtcaagacc ataggattct cctaatttta tgacatcttc ttttactgga
    74341 gaaccatctc catcaatgaa tagcctcatt ctttttcgcc ttcttccata aatgataaac
    74401 agttactaat ccgctcagta aaagaccaac attgatccat tttgccaaga taagcagttg
    74461 tacactttct atcggcactg attcatggtt cagcgtgatc aataatagat ggattggctc
    74521 tcccatttct tttgctaaaa caaacaaaag cgtcatcaat aaaaactggt ggatcacact
    74581 ccctttattt tgagtagtat acttgacaac gatccggcga tccattggaa tagctgtatc
    74641 agtttgataa tattccttat ttagccagct gcctgttact acgtgccaga aactaagcag
    74701 aaagacacct atcgcaaaac catttggaat caagaggacc aataaagaag aactcagtcc
    74761 aagcaattgc atagccaatg gagaccatgt taaacgtttc aaaatccatg gtccgactat
    74821 ttttgctgca atcaagcctg ctgcataagg caaatacata aaaatcgaaa gtttttctaa
    74881 tccgtacagt atgccaacat aaaaactgct aaataaaaaa aggaaattcc ctagcattcc
    74941 atttagaaaa gtaaacagat ttagccagct tggcaacttc cattccttct tctggtgtcc
    75001 taaaacaaac acgaacaaga tgaacagcag caagaaacca taaatagcaa gatcaaaaag
    75061 cctttcatcg aataacaatc gggcatttct caaaagaaac aataagccaa agaatatcaa
    75121 aaataaaaca agctctcgcg tagctaccag atttcttttg atgtctttga aatccagttc
    75181 gtaacgcgga taatgactaa ccgtatggta ggccatgacg taaaaaagtg tataaatagt
    75241 aaagcttgct gcaatctgag tcggtgcagg caactcaatc gcttgataca ggagaaatag
    75301 ccagatagct gcaaataagt actttttccc atccatattg ataaaacctt gcgtcttttc
    75361 gtgaaaattg accgtggtat tagcaggtac aagccatgct gcactcagcc ctagcaaaac
    75421 acttgaaaaa taaaataaag gaaaataaaa tacgcctaat attccaagca atgaaccagc
    75481 accaccaatc agcagagcga tcatcagcaa cgtgtaacta tctagaccaa atcgtagact
    75541 gttgactaaa aatagtccag tcatccgaaa ggcataaaac agcgtaaatg gcaaaatcgt
    75601 cagccaatta tgcgagtctg ttagtcccaa aaataaaaga taaggaataa aaataaccgt
    75661 gttacttaag ataaagggcg ttgtttgtgt aaaattacgc ccaaatcgtt tgagtttttc
    75721 gaacatgaca atggctcctt aaacagtctt ataactaatc tgctcttcga ttttagcatt
    75781 aaaggggaaa taaaccaatt ttacagaata tattcttgta aaaaaaaata cagaaagaag
    75841 cataagcttc tttctgcatt tttacggtac ttgattactc aagcagacaa gcccttctcc
    75901 acaaaagtct tgcccgacac ccctgcatcc ggcaggtgat aaagatagaa atcaattatc
    75961 ctgtgcctcc aaaatcaatt aggagctctg taaaccagag tccttctcga cccgtcgcat
    76021 aaatttactt taacacagtt cctatgttta tgcgagagct tttttcattt tataatcgac
    76081 catttgaaat ccttgaccga tatctgaaat aagttcttct gtaatctcaa atccttcatg
    76141 cttataaacc tcgattgctt gatgattccc ctgattcact cgcaaaaaga tctctctttc
    76201 ctttgtttgc gcagcaagtt cttcatacca gcgaaaaact gaagaagtca atccttgacc
    76261 acgtacttta tttagcaaat ataatttact taaataaatt tttccattta tctcttcata
    76321 agcagtgtaa ccgacagtct tttcttcgct ttttaataaa aagtaggaca caccttctgt
    76381 cagttctttt tgaatctgtt tttttgactg ataagttttc agcatgtaat ccacttgttt
    76441 ttgaccaatg atcggcacaa aaacttccgg ccatacttct tgtatgactg ccatcagctc
    76501 atccagttca ttttctgtta cttttatttt ttccatacac ccacgtcctt ttttacatta
    76561 taaatgacct tgcgcttgat ggaataaaaa gagcatgatc atgctataca cacccaccga
    76621 ccacggtttc aagaaaatca caatctgcat aaattcccta aaagataatt tcgtcaaacc
    76681 agctactaga cagatcaagt cgtctggcgc aaagggaagc agcaaggtaa caactagtac
    76741 ttttttaata tctttcgttt ttcttgtcag caattcatca aatttctgat acttttttgg
    76801 cgataaaata agctggacaa aggctacgcc atagtaacgg acaagcaaaa atccgattgc
    76861 ttccccaatc actaggccaa tacaactata taaaagccca aatccattgc caaacatcag
    76921 catgcccgct actgaggaga tccctcccgg caaaatagga atgatcactt ggatcacttg
    76981 caacagaaca aatatcatca ctgcatactt gccaaattgc tggataaacg cttgcaaaga
    77041 cgtgctcgat cgaaaaatcc catgatgata agcataaaga atcaacacaa agaaaaaaaa
    77101 cagaccaata atgggcatga tctgaagaca tttttgtaaa actgatcctt ttttagacat
    77161 ctatattccc cacatctttt ttcatttatt aaaactgcct cc
//
LOCUS       DBBGSP010000005        72789 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000005 DBBGSP010000000
VERSION     DBBGSP010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 72789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.005"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(19..729)
                     /locus_tag="ACIZE9_000415"
     CDS             complement(19..729)
                     /locus_tag="ACIZE9_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HGC6092309.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(726..2198)
                     /locus_tag="ACIZE9_000416"
     CDS             complement(726..2198)
                     /locus_tag="ACIZE9_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HGC6092310.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            2336..2809
                     /locus_tag="ACIZE9_000417"
     CDS             2336..2809
                     /locus_tag="ACIZE9_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC6092311.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(2962..3513)
                     /locus_tag="ACIZE9_000418"
     CDS             complement(2962..3513)
                     /locus_tag="ACIZE9_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC6092312.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            3618..4148
                     /locus_tag="ACIZE9_000419"
     CDS             3618..4148
                     /locus_tag="ACIZE9_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HGC6092313.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(4631..5074)
                     /locus_tag="ACIZE9_000420"
     CDS             complement(4631..5074)
                     /locus_tag="ACIZE9_000420"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6092314.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(5090..6250)
                     /locus_tag="ACIZE9_000421"
     CDS             complement(5090..6250)
                     /locus_tag="ACIZE9_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC6092315.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            6757..8457
                     /locus_tag="ACIZE9_000422"
     CDS             6757..8457
                     /locus_tag="ACIZE9_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092316.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(8559..9392)
                     /locus_tag="ACIZE9_000423"
     CDS             complement(8559..9392)
                     /locus_tag="ACIZE9_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGC6092317.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(9696..11861)
                     /locus_tag="ACIZE9_000424"
     CDS             complement(9696..11861)
                     /locus_tag="ACIZE9_000424"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGC6092318.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            12121..14415
                     /locus_tag="ACIZE9_000425"
     CDS             12121..14415
                     /locus_tag="ACIZE9_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HGC6092319.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            14408..15073
                     /gene="pgmB"
                     /locus_tag="ACIZE9_000426"
     CDS             14408..15073
                     /gene="pgmB"
                     /locus_tag="ACIZE9_000426"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HGC6092320.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            15066..16073
                     /locus_tag="ACIZE9_000427"
     CDS             15066..16073
                     /locus_tag="ACIZE9_000427"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGC6092321.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            16095..17114
                     /locus_tag="ACIZE9_000428"
     CDS             16095..17114
                     /locus_tag="ACIZE9_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6092322.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(17395..18762)
                     /gene="nhaC"
                     /locus_tag="ACIZE9_000429"
     CDS             complement(17395..18762)
                     /gene="nhaC"
                     /locus_tag="ACIZE9_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HGC6092323.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(18871..20292)
                     /gene="tyrP"
                     /locus_tag="ACIZE9_000430"
     CDS             complement(18871..20292)
                     /gene="tyrP"
                     /locus_tag="ACIZE9_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HGC6092324.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(20535..22412)
                     /gene="tdc"
                     /locus_tag="ACIZE9_000431"
     CDS             complement(20535..22412)
                     /gene="tdc"
                     /locus_tag="ACIZE9_000431"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HGC6092325.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(22703..23959)
                     /gene="tyrS"
                     /locus_tag="ACIZE9_000432"
     CDS             complement(22703..23959)
                     /gene="tyrS"
                     /locus_tag="ACIZE9_000432"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGC6092326.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(24071..24276)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            24539..25840
                     /locus_tag="ACIZE9_000433"
     CDS             24539..25840
                     /locus_tag="ACIZE9_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGC6092327.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(25909..26508)
                     /locus_tag="ACIZE9_000434"
     CDS             complement(25909..26508)
                     /locus_tag="ACIZE9_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6092328.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            26762..27643
                     /locus_tag="ACIZE9_000435"
     CDS             26762..27643
                     /locus_tag="ACIZE9_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGC6092329.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            27656..29266
                     /locus_tag="ACIZE9_000436"
     CDS             27656..29266
                     /locus_tag="ACIZE9_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092330.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(29343..30002)
                     /locus_tag="ACIZE9_000437"
     CDS             complement(29343..30002)
                     /locus_tag="ACIZE9_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGC6092331.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVALYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(30285..30950)
                     /locus_tag="ACIZE9_000438"
     CDS             complement(30285..30950)
                     /locus_tag="ACIZE9_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HGC6092332.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(31097..31702)
                     /gene="dhaL"
                     /locus_tag="ACIZE9_000439"
     CDS             complement(31097..31702)
                     /gene="dhaL"
                     /locus_tag="ACIZE9_000439"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HGC6092333.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(31730..32740)
                     /gene="dhaK"
                     /locus_tag="ACIZE9_000440"
     CDS             complement(31730..32740)
                     /gene="dhaK"
                     /locus_tag="ACIZE9_000440"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HGC6092334.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(32715..33110)
                     /gene="dhaM"
                     /locus_tag="ACIZE9_000441"
     CDS             complement(32715..33110)
                     /gene="dhaM"
                     /locus_tag="ACIZE9_000441"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HGC6092335.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            33264..33584
                     /locus_tag="ACIZE9_000442"
     CDS             33264..33584
                     /locus_tag="ACIZE9_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HGC6092336.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(33696..34553)
                     /locus_tag="ACIZE9_000443"
     CDS             complement(33696..34553)
                     /locus_tag="ACIZE9_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGC6092337.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(34661..35965)
                     /locus_tag="ACIZE9_000444"
     CDS             complement(34661..35965)
                     /locus_tag="ACIZE9_000444"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC6092338.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(35962..36471)
                     /locus_tag="ACIZE9_000445"
     CDS             complement(35962..36471)
                     /locus_tag="ACIZE9_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092339.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(36646..38781)
                     /locus_tag="ACIZE9_000446"
     CDS             complement(36646..38781)
                     /locus_tag="ACIZE9_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HGC6092340.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(38864..40519)
                     /locus_tag="ACIZE9_000447"
     CDS             complement(38864..40519)
                     /locus_tag="ACIZE9_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC6092341.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(40521..40835)
                     /locus_tag="ACIZE9_000448"
     CDS             complement(40521..40835)
                     /locus_tag="ACIZE9_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGC6092342.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            41005..41265
                     /locus_tag="ACIZE9_000449"
     CDS             41005..41265
                     /locus_tag="ACIZE9_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HGC6092343.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            41279..41593
                     /locus_tag="ACIZE9_000450"
     CDS             41279..41593
                     /locus_tag="ACIZE9_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HGC6092344.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(42323..42877)
                     /locus_tag="ACIZE9_000451"
     CDS             complement(42323..42877)
                     /locus_tag="ACIZE9_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HGC6092345.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(43003..44932)
                     /locus_tag="ACIZE9_000452"
                     /pseudo
     CDS             complement(43003..44932)
                     /locus_tag="ACIZE9_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(45238..45954)
                     /locus_tag="ACIZE9_000453"
     CDS             complement(45238..45954)
                     /locus_tag="ACIZE9_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGC6092346.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(45955..47778)
                     /gene="glpO"
                     /locus_tag="ACIZE9_000454"
     CDS             complement(45955..47778)
                     /gene="glpO"
                     /locus_tag="ACIZE9_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGC6092347.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(47792..49288)
                     /gene="glpK"
                     /locus_tag="ACIZE9_000455"
     CDS             complement(47792..49288)
                     /gene="glpK"
                     /locus_tag="ACIZE9_000455"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGC6092348.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(49424..50884)
                     /locus_tag="ACIZE9_000456"
     CDS             complement(49424..50884)
                     /locus_tag="ACIZE9_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092349.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(50874..52169)
                     /locus_tag="ACIZE9_000457"
     CDS             complement(50874..52169)
                     /locus_tag="ACIZE9_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC6092350.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(52501..53178)
                     /locus_tag="ACIZE9_000458"
     CDS             complement(52501..53178)
                     /locus_tag="ACIZE9_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HGC6092351.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(53208..54299)
                     /locus_tag="ACIZE9_000459"
     CDS             complement(53208..54299)
                     /locus_tag="ACIZE9_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HGC6092352.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(54400..54834)
                     /locus_tag="ACIZE9_000460"
     CDS             complement(54400..54834)
                     /locus_tag="ACIZE9_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGC6092353.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(55418..56875)
                     /locus_tag="ACIZE9_000461"
     CDS             complement(55418..56875)
                     /locus_tag="ACIZE9_000461"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6092354.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(56872..58767)
                     /locus_tag="ACIZE9_000462"
     CDS             complement(56872..58767)
                     /locus_tag="ACIZE9_000462"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGC6092355.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(58825..60600)
                     /locus_tag="ACIZE9_000463"
     CDS             complement(58825..60600)
                     /locus_tag="ACIZE9_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HGC6092356.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(60650..62146)
                     /locus_tag="ACIZE9_000464"
     CDS             complement(60650..62146)
                     /locus_tag="ACIZE9_000464"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6092357.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(62340..63962)
                     /locus_tag="ACIZE9_000465"
     CDS             complement(62340..63962)
                     /locus_tag="ACIZE9_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGC6092358.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(64290..65603)
                     /locus_tag="ACIZE9_000466"
     CDS             complement(64290..65603)
                     /locus_tag="ACIZE9_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGC6092359.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(65848..66072)
                     /locus_tag="ACIZE9_000467"
     CDS             complement(65848..66072)
                     /locus_tag="ACIZE9_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092360.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(66092..66514)
                     /locus_tag="ACIZE9_000468"
     CDS             complement(66092..66514)
                     /locus_tag="ACIZE9_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6092361.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(66656..67366)
                     /locus_tag="ACIZE9_000469"
     CDS             complement(66656..67366)
                     /locus_tag="ACIZE9_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HGC6092362.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(67384..67881)
                     /locus_tag="ACIZE9_000470"
     CDS             complement(67384..67881)
                     /locus_tag="ACIZE9_000470"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6092363.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(67918..68370)
                     /locus_tag="ACIZE9_000471"
     CDS             complement(67918..68370)
                     /locus_tag="ACIZE9_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC6092364.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(68505..69110)
                     /locus_tag="ACIZE9_000472"
     CDS             complement(68505..69110)
                     /locus_tag="ACIZE9_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGC6092365.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(69560..70180)
                     /locus_tag="ACIZE9_000473"
     CDS             complement(69560..70180)
                     /locus_tag="ACIZE9_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6092366.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(70182..71051)
                     /locus_tag="ACIZE9_000474"
     CDS             complement(70182..71051)
                     /locus_tag="ACIZE9_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HGC6092367.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(71074..71481)
                     /locus_tag="ACIZE9_000475"
     CDS             complement(71074..71481)
                     /locus_tag="ACIZE9_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGC6092368.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(71500..72789)
                     /locus_tag="ACIZE9_000476"
     CDS             complement(71500..72789)
                     /locus_tag="ACIZE9_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC6092369.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        21055 a        15324 c        12665 g        23745 t
ORIGIN      
        1 tacatggtgt tcaaaatatt attcgccttt tgcttctttc actaattttg cgaatgcttg
       61 ttgttggaat tcagcagcta aggctttcgt acgttgttct tgctctgctt tgctcatttt
      121 tggattttca gtcattgctt ttaccatacc gtcttgaaca taagcttttg cttcactttc
      181 catcgtactt tgctgtttct tcactaattc agctaacttg gctgcttggt ccgtacttaa
      241 ttctacccat gtctctggga ttttgaatgt attcactcgg ctgtcatatt cgtgattgtt
      301 atcagcaata ttgaaccaga atttatacat gtcgtttttg tattcccaat aagtagtttt
      361 cgtcactttt tcagcatcgc cgtctgtctt ttctacttta tttgtttcgt tatccgtacc
      421 agttgctttt ggtttttctt gtttttcatt tgttcggtaa agatacactt tttcttttcc
      481 attccctaaa gctttataca aaagcatatc tgctccttgg gaatcagcac tggaaacaat
      541 tttttctgtt tttgtttccg ttactttttc cattccaaag tgattggaca aattagcgac
      601 gatcaaactt agtgaagcga cgaagattag tccgaaaatc aaagataaaa aggtttgcca
      661 tgttttttta gcgaacacgt tcgttaaagc aaaagcaagc aagctgacaa tcaaaactcc
      721 aataatcatg cattatcccc cgctttcatt agaacaggtt cttttttctt caataaaaag
      781 gcaataataa agccaagaat cccaaagatg atcgctacga taaacgcggc atggtaacct
      841 gacagtgtgg cattgattgc ctgatcttta taagctaatg gcgtattatc caatacagat
      901 ttgcttggga tatttgcttt tgtcacattc gtcaacacac tgatcaaaat agctgtacca
      961 atcgagcttg cgatttgacg gaatgtatta tttaccgctg tcccatgact gatcaagtta
     1021 tttggcaatg cattcatacc agaagtcgtt accggcatca tgaccatgga gatcccaaac
     1081 atacggatcg cataaaggat cacgatatat aaaactggag tcgtttttgt caagaaagca
     1141 aatggtgcag ttgccgctgt caaaatgaac atccctgtga tggctaaacg tttcgcgccg
     1201 tatttatcga aaatcgcacc cgtcacaggc atcatagccc ccatgatcaa tgcacccggc
     1261 aacaacatca agccagaatg gaatgctgat tctccacgaa tattttgaat atacaatggt
     1321 acgaccattt ctgcccctac catcgccata tttgttacac cagctaaaac agctgcaatc
     1381 gtgaatgtag atgatttgaa tacacgaagt tccaagaatg gatgttccaa atgtaattga
     1441 cgccatgaga acaaggcgat gaaaatcaca ccaacaacta agaaaccaat tactttcaag
     1501 cttccccagc cgtcatctcc tacactagaa aatccgtaaa gtaaactacc gaatccaatc
     1561 gttgataaaa tagcggataa aatatcaatg ctaggatttg acaatggaat aacacttttc
     1621 attaggaaga atgctaaaac caagacaaga acaacgattg gcagtaccat accaaacaag
     1681 tcacgccaat ggtagttatc aatgatataa ccagataatg tagggcctaa agcaggagca
     1741 agtccaataa cgatccctga catccccatt gctgatcctc ttttttctgg cgggaaaata
     1801 gatagcatga tattttgcaa taatggcatc gatactccca caccgcaagc ttggatcaaa
     1861 cgaccgatta gtaatgtact aaaattaggt gctgtaaagc aagtaatcgt tccgatcaaa
     1921 aagatcgtca tggcagaaag atataaattt cttgaactga atttattgat cagccatgct
     1981 gttattggga tcatgatccc gttgactagc aagaaaccag tcgttaacca ttgcacatca
     2041 gacgctgaaa tatcgaaagc tttcatcaat gtaggaaaag ctgtcgtcaa taaggtctga
     2101 ttcaaaacgg tacaaaatgt accaattaat aagacaacaa ctaaaagtgt ccgattatat
     2161 ggttttccgt aaatatctac gggttggttg ttactcatat ttctccttct ttctgaattt
     2221 tttctgaaac tactagaata ctttagtcct aaattcgcta tttgtcaacc tacttgacac
     2281 ataagttaat acggatataa ttaagggaag caagaggaca aaaggagtga caaaaatggt
     2341 tggggcttcc cttaaacgtt tgttggaaaa tgatcaattg gttgttggca tcagtgaatt
     2401 aagtgatatc gtaggtgtgt ctccacgtca attaaggtat tgggaacaaa agggattcat
     2461 tcgttcgatc gaagctgatg cgaattgtcc tagaaaatat cgtttaccta cagtcataaa
     2521 agtagaactg atcaaaaaat atttagatga cggatttact ttgtcaaaag ctgcagaaaa
     2581 ggcagaaatc cgccaaaaga aaatgcacca tgtccgtaaa gttttttcaa aagcaatcaa
     2641 agatatcgaa ttgatcgacg aacgctatac gattttacaa atcggtaact tcaaagaaga
     2701 gaatgctaag atgtacatca ttcatgacaa cgagacagac gaattaactt acaagctcct
     2761 tcctgtcgat gaaaaagctg actacgaaca gttgttaaaa gaactctaaa cgccactaat
     2821 ctcctaagta ccaagctttt taataagtag atgctacata aatacttgaa aaaaggcctg
     2881 tttgaacata agaatatccg aacggtgatc tgcgtttctt tcatatagaa aggaattctc
     2941 catcactgtt cggatatttt tttatttttt tcggttactt tcttctaata catctgttag
     3001 ccaatttgca tattctgttt cccgattgat cgcatgcgct aaaatcaggt agtgtccgta
     3061 attttcatgt ttttcttttt cagtaggaaa gatcgttttt tttcgctcta atagatgaag
     3121 tcgtttttct tcatgaaggt cacgctgctg ctgaataatt tctactaatg ccggatcatt
     3181 cacgtctttg acgaaataca atttcagaac aaattcgtct cgattaaccg gtagttcatt
     3241 ggtgggtgta tgaatccact ctgccaattg ttccttccct tcttctgtta attcataaac
     3301 tttcttttcc aatttttcac ctgtgatctc tacttgatgc tgaatgattc cttgctcttc
     3361 catttttgca agttcaggat aaatctgact atgttttgct tgccaaaatt ctcctatttc
     3421 atttttgaac gattgattca attcatatcc tgtcatcttc ttcttactta ataaccctaa
     3481 caaaatatat cgaagtgtat tttttcttgc catcagtttt ccctccttga caaatcttta
     3541 aatccattct atcataaatg agtaatcgaa aacatgtagt ttattacatg ttttaattta
     3601 taaggagatg cttaaacatg aaagaattta aagaattgga agattttatt ggaactcact
     3661 ttatctatac gtatgacaat ggttgggaat atgaatggta tgccaaaaat gaccatactg
     3721 ttgattaccg tatccatggc ggaatggtca aaggccgttg ggtaaaagac caagaagctg
     3781 atatcgttaa attgacggac ggcgtattca aaatcacttg gacagagcca acagggacag
     3841 acgtggcatt ggactttatg ccaaatgaaa agaaacttca cggaatgatc tttttcccta
     3901 aatgggttga agaacatcca gaaatcactg ttactttcca aaacgaacat atcgcagaaa
     3961 tggaagcagc tcgtgaaaaa tatgaaactt atccaaaatt acttgttcct gaatttgcta
     4021 cgatcactta tatgggtgat gcaggtatag acaatgaaga tgttattagc gaagaaccat
     4081 acgatggaat gccagatgat atccgtagcg gaaaatactt cgatgaaaat tataaacgag
     4141 taaaataagg ttgtgaaaga gaggttgtga aatcagcgtt ctgacctgag tattagagaa
     4201 agaaacggaa aaatagttcc tcatgttttg ccgttttttg agctaatacc gagggtcagc
     4261 tgattgaaca ccgtttatca agaggttgtg aaatcagcgt tatgctttga gtaataagaa
     4321 cgctagttag aaaatagctt ttcatatttt ctaggctagt gggcttatta ccgagaagca
     4381 gccgtttgaa caccgtttat caagaggttg tgaaatcagc gttttgacct gagtattaga
     4441 gaaacaaatg gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
     4501 agctgattga acaccgttta tcaaagattg taacaactgc atattcacac agttaaatta
     4561 gtgacttcaa aatgaaataa tgctcccagc aaaaaattag gctgggagca ttatttcgtt
     4621 attctgttca tcaaaaatca gcgttttgat tccatttcat cacaagttcc tcctcattta
     4681 ctgcttcatc tttttgctgt gtttgaattg taaaaccttg tgaaagatag aaatgaatag
     4741 ctgattgatt tttttgatag actgtcaaag tcagtgtttt attggtttct tttatttttt
     4801 tcattagttg cgtaccgatt ctttgttgcc ggtattccct tttcacaaag attcctgcga
     4861 taaactgatc aatcacccca gcaaaaccaa taatttcttg atctatttct gctaagtaaa
     4921 tcactgcatc tggtaaagct ttcctaacag attctacttg attctcccaa taagttgatg
     4981 gaatgaattc atgagaatcc aagttagcat gcagccaaat cgatagaaca gattccagtt
     5041 ctttggcaga caattttgtt gttgtgcgga tcattttttc tctccttact tattcattga
     5101 ttttaaaata aaaaccattt ttttgaagct cttttacaag ttttcgcccc tcaaaaaagt
     5161 atatcttctc ttgttttact tttctaatac caaaagaaac agcaacttta ggatcatcag
     5221 ctgaaacgat tcgataagtt ccaccaggca attgatccag cttgactttc ccatgatggt
     5281 cgctttgtac tgaaaacggc acaccatttc tagtaagtgt ttttttctta tgtttcaaaa
     5341 tgaatgaact accatttacc ggtttccctg acgaatcact aataataaat gaaaaatcaa
     5401 gcactttttt acttaatcta tactgataga ttagtcgtcc gataaacact aacagtatga
     5461 ctacagctat tatcgttcct gcaagaataa accattgccg catggttctt tcctgatttc
     5521 cttttccttc ttcttttttt accgattcgt tataaggaat ccgatgtcct gtcactagca
     5581 aacgatgcgt gttgatcata tacggcgtac atgtaagcaa ggtaactaag tcttctcctt
     5641 ctgaaatcgt tagaacagac gtgtcatctg gcagtaccac ttgtatattt ttaacttgat
     5701 aagccaattt ctcccccaaa acagtcaaaa taaacgtgtc tccgttttct aaacgatcta
     5761 attcggtaaa taaccgtcga ttaggtaaac cgctgtgagc agagatcact gaatgcgtcg
     5821 aatttccacc aagcgggaaa gaggttcctt gcaagacgcc tgctccattt tcaaggatcc
     5881 taccattgag ccgatcataa agtgaaatat ttaattggat cttaggtata ttgatacttc
     5941 cgatcagcca ttcctctaat tggctggatg ttgtactttc atttctgttc ttttcattga
     6001 aaggatcagt accaggattg aatccttggt cagttaatcg ttggtttttc tcctccattt
     6061 tctttcgctg cacttcaatt tcagctgcgg tccgtttttg tacttgttcg atacgttttt
     6121 gatcaataaa actatttaaa gaatccacat aaaatggata taaagcgatc agtaacccta
     6181 cgacgataca tattaataaa aacaaacgaa acaaaagtcg acgagactgt ttttgcttac
     6241 tctgcttcac atgtgtcctc ccttgcaagt ttttttgttc tttcttttat tatatgggtt
     6301 caggaaaaaa atagaaaatg aaagccgatg aggttgtgaa aaagctgtcc tgcatcaagt
     6361 aataagtaca gcccaaaaaa atagctactc atattttttg ttgggttggg cttattaccg
     6421 cagatgcaag cttttgaaca ccgtttaagg aagaggttgt gaaaactgcg ttatgctttg
     6481 agtaataaga gcgctagtca gaaaatagct tctcatattt tctaggctag tgagcttatt
     6541 accgagaagc agctgattga acaccgttta ccgagaggtc atgaaaaagc tactttgttt
     6601 cgagtattaa gaaaaattct gtttcaaaac aaggagatgc aacaaaactt atgtcgcatc
     6661 ctctctcctt agaactttca cttatgtttt tcttgtaaaa ttcataaata ttttcatgaa
     6721 ttttctaatt tcttgcctac ctctcgcata ggatatatga tgaatttatc taaagtttgc
     6781 aaaggagttc gacaattgaa aaaatatggc ccatttttag caattttttt cattgctttg
     6841 gcatttctca tgcctcattt attcacacat aaactaattt tgggtgctga tgccccattc
     6901 cattacaatc ggttctatga tgccgcgcaa caaattaaat atggggattt ccattatttt
     6961 ccttcccttt atggattcca gcaaagtggc aggatcgtga atgccgttta cggcccattt
     7021 ttcgcttatt tacaaggatt gatcgtgttg cttgcaggta gctggtttca ttatcagatt
     7081 ctttcaaatt tcattcttta tcttatttca ggattttcta tgctgatttt actgagatat
     7141 gtcaatgttc gaaattgggt aagtgtacca gtagccgttt tattcatgag tacgtattct
     7201 attcaatact ggtctatcaa ccaaggattc actagctggg ggacttgttt ttatccttta
     7261 tgtatgatcc ctattgctga tttcgtcctt cataaaaagt tccctgttat caaagtcgct
     7321 gtctcagtgg gacttatgac acagatccat ttactgtctt cgatcatgtt agctttgatg
     7381 tatatccctt tttatcttta ttactttttt aaccagactg aaaaaggaaa agcactgctt
     7441 caactgatta agtcggtctt gctttatttt gttctgacag caaatatttg ggcaggatta
     7501 gctattgttt acagtgggaa taagattctt cctccctttg ttaacagaga aatgagtcaa
     7561 aaggcgatag atctggatgg cagttattgg ctccattacc ctaaggcctt tcctatattg
     7621 atattatcag gttttttgct ttttattttc tttcaacaaa agaacacctt attccaaaaa
     7681 atcgtgttgt acacaagtct tgttttcttt tttctttcta ctagcttgat tccatggacg
     7741 acattgatcg aaaaaaatgt gccttttatt agtttgatcc agtttccatt tcgatttttc
     7801 gtgccattta cgctattgct tctactttac cttgcccttt cactgaacca gtggtctgaa
     7861 caaaagtggt tccgtctttt aagtatattt ggcattctta ttttttcagc acagacgatc
     7921 cagaacttat accagcatct ggaaaagtgg gaaaatgaaa catttgtcag tcgacatact
     7981 tatctattcg atacgccgga agaagcaagg aaaacattct tcagcaaaga tatgtctacc
     8041 agcttgttcg ttttccaaaa aaccacacct gactatctgc caatctataa ggagacaaaa
     8101 gacaataaat acgaccggta taacgaagaa atactagaaa acgaaacaac ttttataaaa
     8161 acacatccag gcggtctttt gacaatcaag tggaaaaaca ctggggacaa aactgttcat
     8221 atccctgtta tcgtctacga tcggactgtg ctacagcaaa atggaaaaac attgactgat
     8281 tatgaagtaa cagatatcgg gaccccaatc gtgaagcagc aaaaaggaat caacgagctc
     8341 acgcttcatt atcaaacgcc aatctatttc tatttcattc tttctcttac tttgattggc
     8401 tggtttacct tgctatgttt atttatttat catagataca agcttttacg tgcttaggca
     8461 aaagggataa atacatccga tcaaaaaact ctccaaacgg tataatcgtt tggagagttt
     8521 tattttaatc agttttttta tgttatatgt tatatttttt attcgttcac atctaattcg
     8581 atttccaccc cgtagtgatc actgatgatt ggactatcga tcccatcaaa aatccgttga
     8641 tattttttaa cctgcattcc ttcagggacg aaaataaaat ctatacgcaa tttttctgta
     8701 ttttgttccc aaccatctat tttcttttcc acagtagctg cttttccttt ttcattcgcg
     8761 acaacatacg aatcttgaag aagaaggcaa ctttctctta cagtataata accttgagag
     8821 tctactggat tattgaaatc acctaggaaa aaaagtggta cgcgagtttc caaaaagtag
     8881 ttttccaagt ttttccactc aaaataaaag ccactttttt tatctgtcca ccaagaaaag
     8941 tggcagctcg agacaaaaat gtcctgatca tctatctttg ttttcccaat caagatcttg
     9001 cgtgtctgat aatcttcttt cttttgaaat tgggagacgg taaggacctg actttccaat
     9061 gtttttttcg taagcagtgc atttccttct tcatatttat cataaccgat gtggctcatt
     9121 tcccaactcc aaaaatactc ttttccgtgt tcctttaaaa gctgaactaa acggtaggca
     9181 aaattatctt tacggatagg tacttgattc tttaccggac agaacttcat tagcttcgca
     9241 ggttctactt cttcagattc cagtaattgg ttgatttctt gtaaagcaat cacttcataa
     9301 tcttctaaca ggatcttatc tgctaattct tgcaattttt tctctggttc tggctcaagc
     9361 cagctatgcg tgttgagtgt catgaatttc attggttttc tccttgtctt catttcgaaa
     9421 caaaagggtt gtgacaaaat ttttgtcaca acctctccag caaatagtgt tctcctgcta
     9481 actcctcagt aataagctca atggaccagg agctattttt tgtttggctg tttttatcac
     9541 ttggtgcagg gcagcttttt cacgacctct ccactaaaca gtattcaaac tgctgcttct
     9601 cggtaataag cccaaccaaa cgaaaaatag gaggagctat ttttgtttgg ctgttcttat
     9661 gacttgatgc aggacagctt tttcacaacc tctccttaca ttttaatgga gccgatcact
     9721 ttaccagctg tcactgtacc taattgcttg atcactactt cttctacttt atcgtttgta
     9781 aatacgatca tgatcgttgg atctttttct tcgttttgga tcacatcaag atccatctca
     9841 gctaatttcg ttcctgttcc tacttcttgg ccttctttga cagcaatctc aaaagctggc
     9901 tgattcattt ggactgtatc gattcccata tggatcaaaa cttcgatacc atctttcgtt
     9961 tccagcccaa ttgcatgttt gctagggaaa atacttgtca cttttccagc gatcggcgca
    10021 acaacttctc ttgatgttgg aataacagca aagccgtcac ccatcatttt ttgtgagaat
    10081 accggatctt ttacttcaga taaaggaatc acttctccag aagctgcgga aactagttct
    10141 tgttctatac ctaagtattg cttactacct gcttgtccat ttcctgtaga aaccatttct
    10201 ggctctggaa tctctgctcc tgattgcagc agatcttcga tatctgattt caagacatct
    10261 gcttttggtc cataaactgc ttggactcca ttgtctttga cgatcaatcc catcgcccct
    10321 gctcgtttcc aggcttcttc agtccctact ttttctcgat catttacact tacgcgtaac
    10381 cgagtcatac aagcatcgac atctttgata ttttcttttc ctcccagcaa atgaatgatc
    10441 tggaccactt gctgatctgc tgttcctgtt ccgctgttag atacaacggt ttcttcactg
    10501 tcattgtcgt aatttccgtt acgtcccggt gtagcaaagt tgaatttttt gatcaagaaa
    10561 tttgctaaga aatacgtaac aacaccaaaa gcgatcacac acaacacgaa gttgataaga
    10621 tctccaccta gacccgcttt gatagctaac ggtgtccgag tcagcaattc gatattccca
    10681 aatgaatgga cccgcaatgg caagatatct gccatcgcaa atgcagcccc ttggatcact
    10741 gaataaatga catataatgg cacagcagca aacataaaca tgaactccaa tggttctgtt
    10801 acacctgtta gaaagacagc caacgctgct gaaaaataca ttgatttata tcttgctttc
    10861 ttatcaggat cgacattacg atacatcgca aaagccattc ccatcaagat acctgaagaa
    10921 ccaatcattt gtcctacttt gaaacgagcc ggcgtccagt tatgcaacac aaactcatat
    10981 tgcgacatat cccctgcacc tttaagattc actaaatcag tggcccaagc caaccataac
    11041 ggatcttgcc caaatacttg tgtccccgcc tgtgcgcctg ataaaatctc atacgatccg
    11101 ccaagctgtg tatagttgat aggaatcgtc agcatatgat gcaatccaaa tggcaatagt
    11161 aaacgttcta atgttccaaa taaaaacggt gctagaatcg gtgcgctttc ttgtgattct
    11221 gcaatccata aaccaaaatt attgattcca gcctgtacgt ttggccacac cacagcaaga
    11281 atcaatgcca cgattgttga ccataagata acaacaaacg gaacaaagcg ctttccattg
    11341 aaaaatgaca aagcatccgg caattttcta taattatagt acttattata agccattgcc
    11401 ccgacaaatc cagcgatgat ccctacgaat actcccatat tcaaagctgg tgcttccaat
    11461 acacttgtaa aaaatccttt aaccatgatc ttcgtaccga acagagtgtg ggtaaatgca
    11521 tcttcattcg caagcatgtc acttgtgaca ccaaagatag ccccagtgat ccgattgatt
    11581 aaaataaatg agatcccagc tgcaaatgct ccgcctgctc tttcttttgc ccaacttcct
    11641 cctattgcta aagcaaataa aatatgaaga ttaccaataa ttgcccaacc aatattttca
    11701 attactccgc ccgttgtgac aagcggcgtc caatcaggat tgatcaaggg aattgatttc
    11761 cctatactga tcatcaaccc agctgccggc ataactgcta ccacaaccat taaagccttt
    11821 ccaaattttt gccaaaactc aaaactaaat atctttttca ttccgtttag ctcctttacg
    11881 caatcggttt cgttaaacgt attatagcgt gcgttttctt ttttgtaaat gctttatttt
    11941 ttatttttct gtctatacca ttctataaaa cctataatac gtgtgttccc ttctataatt
    12001 ttctcctaaa aatttatttt tttaagcttt tttctatgaa atattttctt ttgtctattg
    12061 acttgtgcaa tcggttgcgt ttattatgaa cgtataaaac agctcattag gaggagaaaa
    12121 atgaaacaga tcaaacgact atttgctatt gatccatgga aaatcagcac gacacaatta
    12181 gataaaaaaa atcttcgact gcaagaatct ttaacaagta ttggaaacgg ttatatgggg
    12241 atgcgcggga actttgaaga aacttactca ggggaccacc atcaaggtac ttatttggcg
    12301 ggtgtctggt atcccgataa gacacgtgtc ggctggtgga aaaatggtta tccagaatac
    12361 tttggaaaag tgatcaacgc cttgaacttt atcgcgatag atatttcgat caacgatcag
    12421 ctgatcgact tggcttcttt ggaaccagaa gacttttact gggaattaga tatgaaaaat
    12481 ggtgtattat ctcgtacatt cacaatcact acttctacta ataaagtacg catttccttc
    12541 gaacgttttc tgagcattgt caaaaaagaa tcagcttata tctatttaac tatagaaatg
    12601 cttgaaggta gcggaacagt caaactcgta tcaaaattgg atggaaatgt tcaaaacgaa
    12661 gacagcaact atgatgaaca tttttggaat gagattgatc gtggaactat agaagaaatc
    12721 ggctatttga cgactaaaac tattccaaac aactttggga ttgaacaatt tactgttact
    12781 gcagcaatgc gccatttcgt taatggaaaa tcagtcatcc ctgactatca cgaagatact
    12841 ttagcattac atggttgctt gtctgcagaa ttatctcaag gtgagacatg gtcagtggaa
    12901 aaagaaatta tcgttcttac tagtagagat attccagaag cgcagcaagc agaaaaagct
    12961 gtctcagaat taacgaacca gacaaacaat tatatccaag caaaagaaga gcaaacagcg
    13021 gcttgggcag aacgatggaa gcttgccgat gtggtcatcg aaggagacga agaagcacaa
    13081 caaggtattc gattcaattt gttccaacta ttctctactt actacggcga agatgaacga
    13141 ttgaatatcg gccccaaagg attcacagga gaaaaatacg gcggagccac ttactgggat
    13201 acagaagcgt atgctgtccc tctttatctt gctttagcca aacctgaagt aactaagaat
    13261 ctgctgaaat atcggcataa tcaactgccg caagcaatcc acaacgctca gcaacaagga
    13321 ttaaaaggcg cgctttatcc tatggtcacc ttcactggtg tcgaatgcca taacgagtgg
    13381 gaaatcacat tcgaggagat tcaccgaaat ggcgcgattg cctatgcaat ctacaattat
    13441 acgaattaca ccggcgatac ggaatatttg aaaaatgaag gactggaagt tttagcagaa
    13501 atcgcacgct tctgggcaga ccgtgtccat ttttcaaaac gagcaaataa atacatgatc
    13561 cacggtgtga ccggcccaaa cgaatatgag aacaatatca ataacaattg gtatacaaat
    13621 acgatcgcag cttgggtctt gcgttacacg cgagaaaatt atttaactta tcaaaaagaa
    13681 gctgctatca ctatcagcga agaagaacta gccaaatgga aagatatcgc agagaacatg
    13741 tacttcccag ttgacgaaga attaggaatc tttgtccagc atgacacatt cttagataaa
    13801 gatctcatgc ctgtatccga tattcccaca agcgatcttc ctctgaatca gcattggtct
    13861 tgggacaaaa tccttagatc ttgcttcatc aagcaggcag atgtactaca ggggatttat
    13921 ttcttcaatg atacttttac aaaagaagaa aagcaaaaaa actttgattt ctatgaacca
    13981 atgactgtcc atgagtcttc cctttcgcca agtatccatt cgattttagc agcagaatta
    14041 ggaatggaaa gcaaagctgt agaaatgtac cagcgaacag ctcgcttgga tttggataat
    14101 tacaataacg acacagaaga cggcttgcac atcacttcca tgactggtag ctggttgtcg
    14161 attgtccaag gatttgctca aatgaaaact gcccatgatc agttgagatt cgcaccattt
    14221 ctgccaaaaa cttggaaagc ttattctttc catatcaatt atcgcggacg tttattgttc
    14281 atctcagtca cagatgaaca agttactttc gagttattag aaggttctcc tctagaaatt
    14341 tacgtctatg aacagtctta ttctttagcg gatcgtctag aaataacgct aagaaaggag
    14401 gaagcaaatg tttaaagggg tattgtttga tttagacggt gtcattaccg atactgctga
    14461 attccattat cgtgcttggc gaaagcttgg tcaggaaatc ggcattacga tcgaccacac
    14521 attcaacgaa cagctaaaag gcgtcagccg agaagactca ctctctttgc ttttagctta
    14581 tggcggaaaa gaacactctt tttcaaagga agaatttgca gaattagcga aaagaaaaaa
    14641 cgattattat ttagagatga tccagacgat cgaaccaaaa gatgtcttcc ccggggtcgt
    14701 gcctttactg gattctttaa aagaagaaaa aatcaagatt gctcttgctt ctgcaagtaa
    14761 aaacgggcca ttcctacttg aaaaaatggg tcttacacct tactttgatg ctattgccga
    14821 cccggcagaa gcaacaaacg gaaaacctgc gccagatatc ttcctccttg cagcaaaagc
    14881 tgtcggacta aaagcagaag aatgtatcgg gatcgaagac gcgcaagccg gtatccaagc
    14941 catcctctca agtggcgctc aaccaattgg cgtgggacgt gctgaagacc ttggagagga
    15001 gatcccgctt gtccctgata cgacttttct tacgatcgat tacttgaaag aaaagtggca
    15061 tgaccatgga taatccagag atctccgtcg taccagttcc agagactgaa ataaagaaaa
    15121 tcacattgaa gaacgactac ttagaagtcg ttcttctcaa ttacggtgcc cgcctgcacc
    15181 aaatcttcgc accagacaaa gaaggaaaat cagaaaatgt tttattgtct tacgatcgtt
    15241 tcgaagatgt tctaacagac aaaagctttt ttggagcaac tgtcggacct gtagccggaa
    15301 ggatccggga tgcttcttgg ggtgagcata gattggagaa aaactgcgga tcacaccata
    15361 tccacggtgg cacgaaaggc tggtctttcc aattttggga agtagaagtt ttcaaaactc
    15421 catcatcaat aggtgtggtc ttttacttaa aagatgaatt ttctacctat ccaggaccaa
    15481 tcactgctac gatcacttac cgtttaacaa aaaacgaatt agagatgaca acctctgcta
    15541 gtagccttgt tgaaaccatc tgcaatccga ccaaccatgc ctacttcaac ctttcaggaa
    15601 atggaacaag agacatctat gaacatcagt taacggtctt tttagatggt gtgcttgaat
    15661 tagatcaaga aaaactgcct actggaaatt ggacaaaaaa agaaaaactg ccaatcgact
    15721 ttagaaaatc cccaacactg caagagatcc ttgcatgtta tccagatgga ctagatgatg
    15781 tatttctttt gcatcatcct aggctttcca aaacttcctt acaattattc gagaagcatt
    15841 ctggtcgcca aatgactata gcaacttcta ataaaagtat ggtattattt tctacgactg
    15901 gattcgaagc tgatttctct gtcaatggaa aacagatgca ttcaaactac ggattagcaa
    15961 tcgaaccgca agaaatccct gatatcgttc atttccccaa atttggatcg atcaacctcc
    16021 atcctggtca agaacggatc agtcagacga tttatcggtt ctctgcacaa taacaagaga
    16081 aaggtgtttt tatcatggct attaccgtaa aagatgtggc gaaaaaagcc ggtgttgcca
    16141 cctcgaccgt ctctcgtgtc atcaacgatc atcctagtat ttccgagaca acaaagaaga
    16201 aagtccgaaa aattatggat gaactaggtt atgttcctaa catgactgcc cgcaatctag
    16261 gaaaacgcat ttccagtgcc atcggcgtaa tcttaccccc tcttgattca aaagagcgga
    16321 tcggtaaccc attttatctt gagatcatgg aagcaatcaa cgaagaagcg cggaattatg
    16381 atatgactac agcaatcgct actgctaaaa attttgaatt gctgttagag aacgtccagc
    16441 gtatgcattt acaaaaacaa gtagatggtt ttattctagt gtattcagat agtcaagata
    16501 ctgtcattga ttatttatac caaaaccaca tccctttcac tttgatcgga cagccttatc
    16561 atcatgagaa cgaaatcgtt tatgtagata atgataacca gcttctaggt aaacaagcaa
    16621 cagaattttt gatccagaat ggacataaga atatcctgtt tgtgacaaac acgactcatg
    16681 aaagtttgta tttcgaacga tatttcggtt atcaaaaagc aatgatgatg gctggtcttc
    16741 ctgcgttatc cagtgtagta ctagagcatc cggaggatta tctgtccttt gagaaaacgt
    16801 tgaaagaaaa cgaagccaca gcattggtgg tcattgacga tatcttcgcc cttcgcacga
    16861 tgcagttggc gcaaatgtat ggctatgtca ttccagagac actctccgtc attagcttca
    16921 acaactcgat cttctcaaca ttaacacacc cttaccttac aagtatcgat atcgatatct
    16981 ccgaattagg acgtgtcgct atgcaaaagc tgcgcgaatt gatccatgaa gaattgagca
    17041 gtggcgtacg tttggtcatc cctcatcgct tgatcaaaag agagacagtc gttcctttag
    17101 aaaacccata ctaaatagct gactcactaa atacgctgac catttatcct atggtcagct
    17161 ttttatgtaa aagaagatac tacttctaac acattgttta tctgtaaaaa agagcgtggg
    17221 acaaaagtaa agaacacttt tgtctcacgc tctaaacacg tataaacggc ggaagcagaa
    17281 gcaactcctt cggaaataag ctgaaattca caaaaattta aaaagcaatt ttcttgagtt
    17341 tcttcttatt tcttggagtt aaacgcttct gtcccagcct cttttttcct tccttcaatt
    17401 ttttacacgt cgacgattca ataaaaaacc gcctaatatt gtaaagacag gtgcaagaat
    17461 cgagaaaaag gcgaatggca agtaatgcaa cgcgctaact ttcatcgttc ccataatgaa
    17521 tgtgccgctg actccccacg gtacgagaga attgacggtc gcacctgaat ccgctagtgt
    17581 tcgtgtcaaa taggtttttg ataagccaac gtcatcaaaa gaacgcttga atgtttctcc
    17641 tggaagaatg atggacagat actgttctcc aacgatcaga ttgattccga tacagctcaa
    17701 ggcagtaaac ccgactaaac gagaaggtcg gtccatcttt tcttttaatt cttgaacgat
    17761 ggtatcaacg atcagatatt tgatcagtaa cccacctaat gccaatgcaa gtaaaatcaa
    17821 actagcagaa cctaacatac tcatgatccc gcctcgagaa agcagttcat ctagctttgg
    17881 atcaggtgta tttgcgacat aaccattcat caagatgtct gctgcttttc cgaccgtcaa
    17941 acttttctca tggataaaag aaagaacgag agcagctgtc gatcccgcta gtaatgtagg
    18001 gatagccgga atttttttga ttgccccccc aaataaaata actagtggaa tcaatgtcca
    18061 aggagagatc caaaagctcg ctttcatgtt ttggatcatt tcattgatac tagctagatc
    18121 ggctgaatga ctgttatgtc ctaatatcgt ataaaaaatc aacgaaagga cgaatgctgg
    18181 gaaatccgta taacgcatac cagcgatatg ttcgaataga ttaactcctc caatacccgc
    18241 tgccaagttg gtcgtatctg ataaaggcga gcagttattc cctaaaaagg caccggaaac
    18301 gactgcgcct gtagtcattg catcattgaa tccaagtaaa tgaccgatcc ccaaaaaagc
    18361 aattccaatc gtcgaaatcg ttgtaaatga actgccgaca gtcactccga caattgcaca
    18421 aacaagaaat gctgtcggta aaaagaaacg cacagaaaca agtttaaatc cataaaccat
    18481 aatcgtaggg atggttccag ataaaatcca tgaagcaact aagacaccaa tcaaaagaaa
    18541 aatcaggatt ggaatgatcc ctggagtgat tcctttgatg atcccgtcat ggatctcatc
    18601 ccatgtgaac tttttaaatc tgccataaaa caacaaacac atgaaagctg caaggatcgg
    18661 gatatgtggc gagagctgga atccgatgat cagtactcct aggagtgcca acaacacgat
    18721 caatacagcg atactttctt ttaaagaaat atttttattc atcgtcgatc tcctatttca
    18781 aatgaaaagg ccctgccatg aaaaaactat tcacttggca ggacctccta ctaaatcagc
    18841 gacaaaacgt cggctgaaag acttattttt ttatttttct tctaaacttt tttctacctc
    18901 aatcccccaa gaatctttct tgaagtgatt gatgatcaat ggaataacga acatgaccac
    18961 tgtgatagct gctactaata atgcatcact caatgtcgct gtacctaatg tagcaaatac
    19021 gacaacgatg atagagaaga tcagcatgca gctgactacc caagctaatc cgtttccgtt
    19081 tttaccaatt cggtaaggac gttcgaattc tggatgtttc ttacgcattt taagcaatga
    19141 aacagcaatc aaaatgtaca cgatacaata aataacagtt gtagcatttg taagtgtcaa
    19201 gaatacagca cttacgtcat ccattacacc ataaagcaaa gcaaataatg aaataacgat
    19261 tgattgtgtt agaacgacat ttctagatac gccgtatttg ttttctttat ggaatccgaa
    19321 ttttggtgga aggaatcctt cacgagctac ttggatgatt gtttttgatg gtccagtaac
    19381 ccaagctgat aattgtaaaa gcacaccaat aaataccatg aagctgaaga tatttccgat
    19441 cacttctggt aagcctagga tttgacagtc aatcaagata ggctgcgtga tatttgctaa
    19501 ttccattttt ccatctggta cgacatttgc tacaagcatc gcattgatga cattcaataa
    19561 aactaatccg atcaaagcga taaatacgcc ttttgtataa ttttttgttg cgtctttcaa
    19621 acgaggcatg taaacagaac tcatttcgat cccaacaaaa ataaatgtga taccagctaa
    19681 gtatttcaat gaatcaatat gttccaagtc agggaaagct tttgaccatg aaaagtcacc
    19741 tagatagccg tttgagacta gtccgacttt gaaggctgcc aaaacaccta aaacgaacat
    19801 gatgactact gggatatata cccctagcca tacaccgatg ttcccgccga cttttgccat
    19861 atcgaatttc aagttcaaga tcgtgatgat ccagtagata actaaaatac aacctaaaac
    19921 gaaccagtga ttattgccaa gttctacatt accaaatgtg tttcctaaca atggtcctaa
    19981 agtagaagcg accattacca tacctgggaa catttgcacc cataatagcc atgcaacgac
    20041 aaatccccat ttgctgccca gtgctgtttt tacccataac tgaggaccgc cttcttgagg
    20101 aagcatcgtg gaaagctcac cggaaaccat tgatatcgga ccggcaaaaa acaaaactgc
    20161 aaaaattgaa taaaaaatca atgtccaacc gactgcggct aacgtaggaa tactccgaac
    20221 cgttgcacac agtgccattg tcagaccgat aaaggtccca agacccattt tacttacttc
    20281 agatttactc accgttgaca ctctccttga ttttttggat aaaataacgg tgtctttgaa
    20341 gtagtttcag caataaacga aacaattcag cgaatatttg aggggattct ttgagtttat
    20401 tgcttgaagg gtttcttcaa agacaacctc aaaacaaagg gatcgaagag cttaggtctc
    20461 cccttgctct tcagatccaa acatgcgtca gaaacagtta gtattcaagc tgttttctaa
    20521 catgattacc ttgcttattt tgcttcgctt gccaataatt ggtctgcgta gattttttcc
    20581 aatttttctt gaagagctgc tttgattttt tcagcatatt cttcaaagtg ttcttctttg
    20641 ttcatgtatg gtgtcattac gctggcacgc aatacagtta cttttccggc acggttccat
    20701 tcttcatctg agaatcctag ttggttcaca aattgtaatg ggctgttgcc atagtctggg
    20761 atagcaaagt cagtatgtga agttaagaac tcattaccgt aaatgcttcc tttcacgtat
    20821 gaagaataat catatacgtc atggttcaat ttattcattg caactaagtc atcgttgcct
    20881 ttttctttga atacatagtc taccatattg aaatctggat aagttaatgg atgaacttcg
    20941 atttctttgt ctcctacttt aaatgacaag tcattcaaga agttgtagaa acgatgtgca
    21001 ccttcgattg atgcacccat taatttacca tatcctgtga cattcaaagg taagacatgg
    21061 tgtgctgccc aaacgctggc tgctgttgcc cctgcttttg aaccttccaa gatataagcc
    21121 ccaagtaatg ctgggatatc tgcgcctttt tcaaatacat atgtcgcaaa gtaagagata
    21181 acgtctctca tgcggatatc tttgatgacg ataccaccgg cagaatatgg aacatagccc
    21241 attttatgtg ggtcaatcgt tacagattct gcttcttcga ttgctttata tgcactgtgt
    21301 acttcttcta agatataatc tttgttttct gtaaagacat tgtatttgta atgaacatct
    21361 tttaaatctt caaatggaat gaagttgttg tcttcgtcta agaaaatcgc acggccgtat
    21421 ccgccataag cagcatctac gtgtaagtag aagtaaatac cgtctttttc taatacgcga
    21481 cgcaatgcaa cgattttatc gataccgtcg attgctcctt cttctgttga tcctacaaca
    21541 ccgactacac ctaggattgg tgttttttca gctgctagac cacgaacgat tttttcaagt
    21601 tcgttgatgt ccatgcgata gttgtggtca actggcactg gaatcacttg gtctaaaccg
    21661 ataccgatga tgtcggcagc ttttagccat gaatagtgtt tagtttgtgg aaccaaccat
    21721 tttcctaatt tttctaaatg ttttccgcta cgtgctgagt gagctttgat ttcgtcgatt
    21781 ttttctggga cgctgtctaa cagattcatg atttcttctg ttgacaagtt cattaattcc
    21841 caatcgcttt ttccagcaac tagttcaggt gtcacttctt tcattgcaag cggcaatgat
    21901 ttgatgttgc gggcatacca aagtccttct aagtttgcta aagaaccatc agcaacgatg
    21961 tggccccagc catctttata gctcattaat tttgcaaatt ccattcctac ttcttcttcc
    22021 atttggcttg ttgcaggaga agattcatag gcaacgttat taccattcca tagcatagca
    22081 aaattgtacg ctagtaaaga tggcatcaat gtttcagagt tcatatgacc ccagtaacgt
    22141 ccggcattat gccaaggaac ggaatgggta cgcatccgcg ctgaaatttc tgatagaaca
    22201 tcctttgttt tattcacagt gtgttcaaaa ctagcactgc ttttttcttc tggcgtaata
    22261 ataggcatgt cttgaggcat gtagttttga cgccagccta aatgttcatc caccaattca
    22321 ttcaacaaag ctttatagat ttggccgttc tcagctttgt ccccaatgaa tagggcattt
    22381 aggtttagat ctttcgacaa tgattcactc atagtgaaac cctcctaaaa aaatatttaa
    22441 attttgtcga gccctacatt acacctgttc ttctattctg taaactaagt tttggcctga
    22501 tttttaatca tattttaata tgtatcaatt atccgaattg ttcacacttt tgaaataatt
    22561 aaaaaaaacg agggaattta caaatgtaaa ctccctcgca aagattgtat taacgacaac
    22621 cagcgttcta ttttaggatg ggtttcaaaa ttggaatgtt gtaatagtat ttcccttttt
    22681 caaggtaaaa acttactaaa ttctaatcaa ttactttggc caaaaagtaa tttttcttac
    22741 cttttcgaat aaccacaaac ttaccatcga attcatcgga tggatttatg acaaaattta
    22801 aatcggtaac gcggtcaccg ttaatactta tagctccgtt tgaaacatct tcacgtgctt
    22861 gacgtttaga tggttcaatt tttgtggaaa caagcagttc cacgatattt tcaggtgtgc
    22921 ttgaaatttc aacgttcggc attttaccga atccttgcgc gatttcttcc gcatttagtt
    22981 ctttaatatt tccagagaac aatgcttgcg ttattttttg cgcttctttc aagtcttctt
    23041 cactatgcac aaatcttgta acttcttctg ccaaacggcg ttgtgcttca cgtttctcag
    23101 gttctgtctc tacttttttc gctaagtctt cgatttcttc ttgagacaag aaagtaaaga
    23161 atttcaagta tttcactaca tcgcgatcat cttgattcaa ccagaattgg tagaactcaa
    23221 atggtgaagt tttcttcgga tcaagccaaa cggcaccgcc tgcagttttt ccgaatttcg
    23281 ttccgtcagc cttcagcatc aatgggatcg ttaaaccgaa cgcttctgct tctggtcctt
    23341 ctaattttcg gattaggtct aatccagctg tgatatttcc ccattggtct gctccaccga
    23401 tttgcaattg cacatcgtat gttttatgca gatgcaaaaa gtcgatagat tgcaggattt
    23461 ggtaagtaaa ctctgtaaat gagattccta cttccaaacg gctggcaacg atatcttttg
    23521 ctaacatcgt gttgatgttg aagtttttac cgtagtctct caaaaattca agtaaagaga
    23581 tttttgacaa ccagtcgtag ttgttcacaa atgtgatatt tgcatcttta ccaaacaatt
    23641 ttctcatttg attggaaagt gcgtccacgt tatgttgcac ttgttccatc gtttgcaaca
    23701 cacgttctgt tttgcggccg cttgggtcgc cgatcgttcc tgttccgccg ccaatcagaa
    23761 tatatggatg atggcctgcc aattggaatc ttttcatcat cataaatgga atcaaatgtc
    23821 cgatatgcat cgaatcacca gttggatcaa cgccgcaata aagtgaaatg ctcttttctt
    23881 caacgagctc gcgaagtctt tcttcgtttg tttgctgatt aatggcgtcg cgccaagtta
    23941 attcatcaat aatattcatt ttactgacct ccgtgtagtt tttttatgaa agcaggaacc
    24001 tgctagcata tgtaattaat tatttcttca ggataggata ggaaataaaa aaagtccctt
    24061 ggcatataag ccaagggacg aaatctcgcg gtaccaccca atttgtatgt ctagatatcc
    24121 aacatacctc tcgaacattt aacgctgtcg cgtggcaatc actgccaaag actcctgaaa
    24181 tgtaattcgc tttaaagcat gtactggttt gcagcgacca ccagctttct gaaacattgg
    24241 ctttaacaac tacttcgttt cgatcttcgt cttgttatta ttaatatgtg tctatcatag
    24301 agcgcaactt tttctttgtc aacagaaaaa ggatattttt tttaaattcc tcattttttc
    24361 ttttttgaat ccgctctaat tccgaacatt ttattttcaa ttattgttaa aagaaataac
    24421 tttttctgta ttttttctgc aatttatcga gaagtcactt tactttgcct cttattcttt
    24481 cttcgttaca ataaggaatg ggacaagtaa aaaaatgaaa aagcaaggga cgaggtatat
    24541 ggaaaaaaag caaaaaatta ttttaggagc cacttctgct ttaactatcg ttattttaat
    24601 tctaagtttg ttttttgtca tccgatcatc tacaaaaaaa gaaccaatca ttcctgaaaa
    24661 aaaaataaca gaaaaagcaa aagaaccgac agatgataag caacaactag ttactcaagc
    24721 aaaaaatctg gctcaaagct acgattatga ccaagcgatt gcgttattgg aaaaagatag
    24781 taagaacgga tctactgaaa cacaacagct tcttcaaaca ctaaaaaagg agaaagaaca
    24841 actgatcgac tggtctgatc ctactcagat ctctcatgtc tttttccaca gcttgatcgt
    24901 ggacccgcaa aaagccttcc actctcaaca ggcacaagga tacaaagatt atatggtgac
    24961 tgttgaagaa ttcaaccgtt cgatcgaaca actttatcaa aatgattttg ttttagttaa
    25021 tttgaatgat ttgatccaaa aagacgaaca aggaaatctt tcctttaacg ggcttgcgct
    25081 acctgaagga aaaaaaccat tggttctttc acaagatgat gtcagctatt atgaatatat
    25141 ggataattcc ggttttccta gccgattggt cgtatcaaat aacaatgaaa tcaaaaatgt
    25201 ctataaagag aaagataaag aagaaatcgg tgactttgac atggttcctc tgatcgatgc
    25261 ctttgtcaag aaacatcctg atttttctta tcgaggcgca aaaggtacct tggccctgac
    25321 aggttacaac ggagttttag gttatcgaac atcaaaatct caatatggag acaatgaaaa
    25381 aacaaaaaaa gagattaaag aagctaaaaa agtggcggaa cagttgaaga aagacggctg
    25441 gagctttgct tcccatacat ggggtcactt gaatatgact caagcttcac tagaagatgt
    25501 aaaaaaagac aatgaattgt ggcagcaaga agttgcacct atcctaggaa aaacaaatat
    25561 tctgatttat ccatttggtg cagacatcag cgactggcag ccttattcag cagaaaatca
    25621 aaaatttgct tacttgaaga gtcaaggttt cgatattttc tgtaatgtcg atgcttctac
    25681 accagcttgg ggacaattag gtacggattt ctatcgaaat gctcggatca atatcgatgg
    25741 cattcgtttt caatctgatt tagacggaaa aaatcctatt cttgatccat tcatcaatgt
    25801 ccatgatgtc tatgacaaag aagcacgcga atctgcttga ttttacgtca tttatgaacc
    25861 aaaaaagccg aactgacatt ttatcgtcag tttcggcttt tttatgcttt atttcttctt
    25921 cggtgcgatt cccttgatca ggacttctgt ccattctgct gtatatggaa gcagttttgc
    25981 gtatatctcc ggcttagaaa ttccttctac cattgcttga aaatagagga tcaagaactc
    26041 atccgaatat ttcaaatcca cttttccttc tttccgccct cgatggaaaa gatcaagcat
    26101 gatactgaaa ctttcttgcg tatacgcatc catcgcgtca gaaaattctt ttttttcttt
    26161 ttttgtatag tatgtcatca aatcgatata aaattgtttg ttcactcgat tgagataacg
    26221 gattttgttt tcactcatgg caatcagtgt ttcttcaaat ggaagatttt ccgcaatcaa
    26281 cgctttcgct tcttgcccta aatcattcat aaatgcaaaa aatacttcat aaatcagccc
    26341 ttccttgctg ccaaaatatt taaaaatcgt cgctttactt acctgagcgt tctcagctac
    26401 cttatccatt gtcactccag cggttcctat gtctgtgttc atcaagtcaa aagctgcttg
    26461 taaaatctct ttctttttct cttgtgctct cttttcaaaa ccgttcattt gtagagcctc
    26521 ccgtaatttt aaacttttat aatatatata gttcaaattt attctgaggt ttattataac
    26581 tatctattga gaaagtatca agctagcaat tccttgttta tgaattcatt gacagaaatt
    26641 tataaaaaga atattatgta ctaaaataat aaaaaaagtt ttataaaaag gtataaaacc
    26701 tttttattaa actatttaat cttgtttagt atatattttt agaaaaagga gtggggtttt
    26761 tatggcagaa atcgtcaaag tcacacattt gaaaaagagc tttggtcgtt tcgaagcttt
    26821 aaaagatgtc tctttcaccg tacattcagg tgaagtcgtt ggatttatcg gaccaaatgg
    26881 ttctggaaaa tccacgacga ttcggacact tttagggatt ataaaaaaag acggcggaac
    26941 ggcaacgatt tttgggcaag atgtatggga agatagttta tctatccatg aacgtctttc
    27001 ttatgttcca ggcgatatct ctttgtgggg aaatttgact ggaggagcga tcatcgatct
    27061 cttcatgaag cttcatggaa aagggagtgc tcaaaaaaaa gatgaactga ttcaacgttt
    27121 ctctcttgat cctaagaaaa aagcaaaaaa ctattcaaaa ggaaatcgcc aaaaagtggg
    27181 cttgattgct gctttggctg ttgattcgga tctctattta tttgatgagc ctacttctgg
    27241 tttagatcct ttgatggaaa cgattttcca agaagaagtt gaaaaattga aagaacaggg
    27301 caaatccatc ctactttctt ctcatattct cagtgaagtc gagcgactag cggataaagt
    27361 cgtgatcata cgcgaaggaa cactcgatga agaaggaaca ctcgatgaat tgcgtcattt
    27421 gactcgttcg accatcacta tagaaacaga agcagagaat agtcacttag cacaattgaa
    27481 cggtgtccat gactttgtgc aaaaaggtca cctcgctcaa tttgctgctg ataacgaagc
    27541 tttcgatgtg attttagctg aagcgtccaa attaggtgtg aaaaaatttg aatctattcc
    27601 accgactctt gaggatttat tcatgagaca ttatgaagga tgaggaggaa gcgaaatgac
    27661 tgataaattt tcacgctggt ccaccctttt ttctcaaaac cttagccgtg actggaaaaa
    27721 gatcctgata tggctagtcg gtgtcactgc tttttctggt ggttttgtcc ctgcgtttga
    27781 agaattgact tccggacaag gattagctgg attatacgaa accttgcaaa acccggcaat
    27841 gattgcaatg gtcggaccaa ctccagcttc gaatgctgct gagtatactt taggagcgat
    27901 gtatgcaaat gaaatgttgc ttttttgcag tttgtttgct gctgtgatct ctgttttaca
    27961 cgtggtgagc caaacgagaa aaaaagaaga acttggtctg attgaactta ttcgttcctt
    28021 tcgagtcgga cgtcaagcaa actctttagc tgtcatcgct gaaagtattc tgatcaattt
    28081 gcttttagca atatcgatca gctgtacgat gatttttttc caagcggatt cgatcactgc
    28141 agaaggtgct tggctttttg ggctatctgt aggtagtatg gggattttgg ggagtgccgt
    28201 tgcactgttt gctgcacaac tgatgccaag ttcagccagt tcgaatggtc tgtctttagc
    28261 gtttttaggt ggactttacc ttctacgagc aataacagat gtagctgatt cctccctttc
    28321 gatgtggaat cctttaggct ggtcttattt gacctatcca tttacaacta acaactggat
    28381 tcctttgctt tatttgtttt tgttcagtct aatcttgata atcagttcat ttgttttaga
    28441 ggaacatcga gatttgaaca ccggctatat ccccgaacgt gaaggaaaac cgtatgctaa
    28501 acgttctctt ttatccttgc gtggtttatt attctatcta aataaaggga tgacaatcag
    28561 ttggcttatc acttttggtt tgatgggggc ggcatacggc tctatctacg ggaatatgca
    28621 acagttttta gaaagtaacg acttaatgaa acagatgttt atccaatctg gcgtctcaat
    28681 tgaaaaaaac tttacaagca cgatcatggt agtcttgatt tgtctagctg ctattttacc
    28741 aattgctagc atcaatcgtt tatttacaga agaaacccac ggacgtatga atcagctgtt
    28801 cgcaacaaaa atttctagga accaacttta ttggaccaat atgttactag ctattctatt
    28861 tgctatattg gcaatcctga ttagttctgg tgcactaggg ctttctgctt tggcttcgat
    28921 gaaggatgcg aaagacatgg atctattgat gtttcttaaa gccgggttca atttcctgcc
    28981 tgccgtttta gtgtttatcg gaattagtgg ctttctattc ggatggcttc ctcgaatcgg
    29041 taaacttgct tatatctact tagcttactc ctttgcactc aattactttg gcggaatttt
    29101 ggatttacca gaatggtttt ccaaaacagc tgtccctagc tgggttccac ggatgccaaa
    29161 cgattctttt gatctttccg tgttccttac gttatcatgt atcagccttg cactgttcgt
    29221 ccttggttct attggttata ggcgaagaga cttactagaa ggataataaa aaagcatgta
    29281 caatttcatg ctagcctcca aatctgggtc aaaaatccaa catttggagg tcattttttt
    29341 atttacaagt cttctaactg ctctttatca atgatccaga cttctcgatt ctttcttttt
    29401 acataaccat tctcctctaa taatttaaat tttctagata aagtttcggg ggtcgtaccg
    29461 ataaatgcag caagttcttt cattttcatt ggcaggaaaa agtgatcctt ccctgtcgct
    29521 ttagctaagt caagcagata gagagcgact cgttcttcta ctttttccat catcaaaaaa
    29581 gttgtctgct gctgtacttt tgttaatttc tcaacgttga ttgctaaaag tttcagacta
    29641 agggcgggat aatgcagtaa gagttccgag aaatcttttt gtctcaatat gcaaatttcc
    29701 gttttttcta gtgcttcgcc aaataaagac tcatttggaa cgcctagcaa ctggctctct
    29761 ccctcatatc cgcccggctc tattactcgt aaaagctgtt cctttccgct agcagataat
    29821 tgatacactt tcatactgcc ggaggccacg atcactaatt gaggttctcc attcggcgca
    29881 agaatctgtt ctcctttttc cacatagtga tgtttgacaa gtgcgtgtac tttttcttga
    29941 tcttgctgta ctaagtgatt gaacaaagga acaaatgaaa cacataaatg atcatgactc
    30001 ataatctctc ctccttctaa acagctattt ctaataaaga aacataactt cccttattcc
    30061 aactgataat tttcttttat catagcataa acgtcaagcg aaccagatac cagcaaatag
    30121 agtggatttc tttttgtccc ttgctttatt ttccttcttt tgagacctta agtaattgat
    30181 tcctatcaat tttttaaata tttacttttt gaataatcaa aaacaaacct tcactcgcaa
    30241 gccgagagta aggtttgttt ttcgcattgc ttatttcgtg ttgtctattg aaatttttcc
    30301 gcacctagct tttgatatag tggtgctagt tcttgtaagg tttcagcggt tatttgctca
    30361 acgtgttcga tttcttgcgg atagaagaat agtttaccca tttgaaaggt tcggtctctc
    30421 atcgcttttt tcaactcttc ttgtttcttt gtatcggaca aatagtcaga caaagctaag
    30481 tggtcgtcaa gttcatgttc tggttgcggc catatgtaat aatccttgat atcgactgtt
    30541 ttgctccact ctttcagtat cgcaagcaac tggttatacg ctgcaatgct accatatcgt
    30601 tcttcgcttt tataatgttg gtacatcaaa tagatttggt attgtttttg attcaacaaa
    30661 actgctagac aggcattctc gtcttgacga gattcgcttc ggtacgcgct ccaaaaatga
    30721 ctgcgtaaat tccagccatt cgtccagctt tcgattttag gtttgctcat gccgtacata
    30781 tcaggcaaaa gtgcagctgt ctggagctga atctctttcc atttttgcca gtgttcttta
    30841 tattctttct tgatttgttc aatcttatct gttggatggc tctctttgag ctgtttgaat
    30901 gcgtagattg gtcgatcaaa caactgataa tctgattttc caagttccat tgtttcgcct
    30961 ctttccgtta tcttttgtat tctacctgaa ttttgcgata tggacaaata gaggttgtga
    31021 aaaagctgtt ctgcatcaag tcataagaac agccaaacaa aaaactgcga tgagcatcac
    31081 cgcagtttta ttgaacttaa ggttgattga tcacatctaa aagcgttgaa aataaaatgg
    31141 cactagaagc agctcctggg tcgatatgtc cgattgcacg ctctcctaga taggaagctc
    31201 gtcctttttt agctaccaag actttggtgt gttcttttgc ctggtcaatg atttcttttg
    31261 ttaaattccc tgccttcaat gcctctgtga ctggcagcca aacatctaac atcgttttat
    31321 cgtcagcttc tgcctttcct cggctttgaa tacccgctgt tccctgctcg atcacttcgc
    31381 ctaatttttc ttgagaatca atagaatcga cctcttttgt cgctttcatc atgttcatga
    31441 atgcagatcc gtataacgga ccagaagccc caccgacttt cgatatcatc gccatagaga
    31501 atactttgaa tgtatcgctg attgtttcag gatgatcggc ttgaaaagct tcttcataag
    31561 ctgaaacccc tcttcccatg ttatttccat ggtctccatc gccaatcggg gtatctagat
    31621 cactgagata ttgtttgttc tgattgattg cctctgcaaa ttgcgtgagc cattcttgga
    31681 tttcttgaac ggttagtttc atattatcac ccttttatct tgagattttt taccatgaaa
    31741 tcgtctgtac attgctttct aaagaatctt tccattgtgt ctccgtcaag tcgatcagtg
    31801 ttagagaaag accttgcata tctagtgagg tcataaaatt accgactttt cggaaaacta
    31861 cattgacgcc tctttcttcc aacagagcta aaacatcatt catgaacacg aactgttcca
    31921 tcaaaggcgt cccgcccatt ccgttgacta gtacacctgc ttcttttggt aaattcgagt
    31981 aatcatctaa aatcttagta acaagttcct ttgccagtac tttagaaggc tgcatctttt
    32041 ctcgacgata gcctggctca ccgtggatac caacaccata ctcgatctca tcttctccta
    32101 gttcgaatcc tggtttccct acttctggta cagttgctgc tcgaagcgct agaccgatcg
    32161 tcttagttgc ctgtacgacc ttttctccca gttctttcaa ctcagctagg gaagcaccgt
    32221 ttcttgctgc atcgcccacg attttgtgta caaggacagt acctgcaact ccgcgttttc
    32281 cagcagtata cgtactattt tcaacggcga tatcatcatc tacgatcaca ctttctactt
    32341 caatatcgtc catagcagct aattcctttg ccatatcgaa gttcaatgca tcccctgtat
    32401 aattcttaac gatcagcaaa actccttttc cactatcggc ttccttaata gccgtctgaa
    32461 tctgatctgg agttggagaa gtaaacacat caccaagcac cgctgcactt aacatccctt
    32521 cccctacaaa cccggcatgg gatggttcat gtccgcttcc tccaccagaa accaaaccaa
    32581 cttgttccgc tttctgattc ttggctacaa cacgggaaga ttctacacga tgaacaagtt
    32641 ctggatagct ttttactaat ccttccagca tttcttcgac aatattgctt ggatcattca
    32701 tgattttttt caatttattc ccatcctttc tttccggcat tttgtgcttc tgttaagatt
    32761 tgctgagtat catctgttat accggcagtg atggctgctg caaaagctcc ttccactaaa
    32821 ggcgcatcca ccagatgata acgttgctgc tgctcttctt ccaacatgtc ttttgccagt
    32881 tccgagttca ataccgcgct accgatatcc gcaaaaacaa aataactagc tgcatcgctt
    32941 gattcattga ctgcttctac gattttcatc gggtctgatc cgatctcgcc atttattccg
    33001 ccgagagaaa aaatttgcac ctcttcggat ttttgcatct gctcaatcat ttctttaata
    33061 ccatctgtta ctttttgact atgagaaata agcaaaatac tttttttcac aagaatcttc
    33121 ctttctttta catagttgct aacgattggt ttcgctttca ttaatgaaca attcaagtat
    33181 ataataaatt tctaattttg ggaaaatatg tgtagtgctt cttgaagttt gttatacttt
    33241 aattaaaaga gaggagtgat cgaatgatta caacaacaac gaacagtgta gagggaaaag
    33301 ccgtagtagc ttataaaggg atcgtttttg gtgaggtcat tactgggatc catgcattta
    33361 aagacttgga ggcggggttg cgaaatatct ttggcggccg ctcaaaaagc tatgaaaacg
    33421 aactaatggg tgcaagagaa gaagcacttg ccgaaatggc cgaacgtgca aaagcattag
    33481 gagctgatgc gatcattggc gtaaaaatgg actatgaagt attaggcagc gacaatggca
    33541 tgctgatggt cacatgtagt ggaacagctg tctccacgag ataagtaggg gacatctgtt
    33601 ttaataacta aagagagatg ggacatgtag tggcactcaa gaattagatt tttcagtcta
    33661 acttcgaggt actctacctt cccatcctct cttttttatt tctttttgcg gatgattccg
    33721 taagctgctg cgactaacac acccgcccct gctaaggaat aactgacaga agctgttttt
    33781 tcatttgttt ttggcaaagt ctgacttgtt gatttggatg gctctgtcgt ttgctgaact
    33841 gtttctgtcg tgcttccaga ggtcactgat ttttctcctg ccgaatgcaa aatatctttt
    33901 attcgttgga aactagctgc taagtcagct ttttttgctt caaaatcatt agcaactgtt
    33961 tgtgcttcgc tgatctttcc gtggattgct tgactggccg ctgtgatatc cgcttgagtt
    34021 tgacttagct ttccagaagc tgtttgagca acctgattta attgctgatt gaattctttt
    34081 gcttgttgga tcttcccgtc aagatctgtt tggacagctt ccgcttttgc tttcgcttcg
    34141 gcaagctttt tctcaagttg tgcacggtca tttcccactt tatttttaag atcagctaaa
    34201 tcttgatcga ttgctgcttg gtcttctttc aatttgtttt ttgcagcttc taatgcttct
    34261 tcgagttctt ttcttttatt ttccaagtct tgcaaatgat cgatttggtc agaagaggta
    34321 gaactattta ttgatgtatc ttctgaagat gaaatcgttt ctcctgaatt atctgtcggt
    34381 acattggaag tcatttctgt ttccgaggca ccgttttcag caccagaaga gcttatggtt
    34441 gttgaaggtt ctgtttgagc aggttcagaa gtttccgcaa aagctgtctg tcccaataag
    34501 aaaatactgg aaacagcaat tggccagatt aacggcttca ttcttttttt catcactttt
    34561 cccatcctta ctacttttta actaatttct tattataagc aaaaatgttt ggaagaacca
    34621 taaacacaac aggctgtttg tctaaaaaac ggtgcatctt ttattttttt gtacgttccg
    34681 ggcttttcca tgtcccgctt ccataaccta aaatcgtttt gactgctgga atgaaagtcg
    34741 tcacgatcgt tatcgcgttc actatccaga acaaaagcat atatagtggt gcgaaaagaa
    34801 ggtatttcaa ttttcttcgt cgatcatcta caatcagcga agctagcaac tggaaaaatc
    34861 ctgcgaccat ttcaaagcag atgaacacaa aactgaatgt aaaagtaata taaatctgtt
    34921 cgtagtttcc ttgatataca taatgcccga ttaatccagc aaaaagaact acggaaatac
    34981 aaaagaatat tgaccagaca atactcaatg tttgatcaat gaagatgatc gttcttccaa
    35041 tatgtttaaa aggatggagc atcacttttt tgaaattcgt cagccagact tctgttccac
    35101 cttttgccca acgttttctg tgtcgatata gcatcttcaa cgtcacaggt acttccatga
    35161 aaaagataat ctcaggagca aaaacagata accagtcatt taactgatga tcccaagcaa
    35221 tactgatgtc ttctgtcgct cgatcttgtc tgaatccgcc cacatcgatc aaggcttctt
    35281 ttcgatacat cgtatttgct ccactgtacg cataaagacc accgaaaaca gctgactgtg
    35341 ttcgtttaat gatgcccacg atacttgaga attcaaccgt ttgagatttt gcaatcaatt
    35401 tggtacgatt ttggacatcc atatttgcag tgaccgcagc aatatgtctt gcaccagggc
    35461 gaatgaaata attcacatac ctaatcagtg catctggctc cggtaccgtg tctgcatcat
    35521 tgcttaaaat caatttccct tttgcaaagg caagtccgat attaaacgcg tgggcttttc
    35581 ctttattttt ttcgatccga accacacgaa gattagcgta ttttttcatc agtctagcta
    35641 atatttctgg tgtttggtcc gttgaaccat cgtctgtcac taatacctca tagttgtgat
    35701 aattcaattt cgtcatcaaa tactcgattg tatattcgat cacaatttct tcattatggg
    35761 ctggcaccat gatcgtgatg aacggttcga cactcaaggg aacatctacc cattcttttt
    35821 gcttatgttt gtataaaaac acataacacc agacaccaat aaaccataca aatccgccta
    35881 aaatcggata agaaacgaga aaaaaataca taatagacaa acaagtatct aagaataaat
    35941 tacctgtatg ggtgattgag atcatttcag ttccacccca ttttctttat acaaatctgc
    36001 aatgaatgtc gtatctagat ttttctcttc ggagacagaa taaaaacgga ccgtttctct
    36061 ctcttctttt gttccaaaac gttccgtata cacttcttca agtaattctt gtcttttttt
    36121 caatttttca tcttcatatt caaaagattt atttactttt ttgtatagat ttcgattgtt
    36181 ccacctagtc aatacaaatg aggtaatcag gaaactgaaa aaaatcaata caaaaaagcc
    36241 gattaagaaa tacagcattt tcttttctga taaaaaagcg tacaaggaaa aatccttggc
    36301 tctttctggt ctcgttaatg ggaaaaagac ccatataaaa ggaagaacaa cgatcatcca
    36361 tcctaaaaga gccactaacg tttgccaaat ctttaaccag taattacctt ttgaaaaata
    36421 cttatctttc accaaaattg atgcaacttc ttctcttgtt acttttttca tatcctcacc
    36481 tcacgttttt ttgttacgac gtaggagttt accatacatt tcatttcttt tcacataaag
    36541 tgttcctaaa tttttcctaa gaaaaagaac aaaacatttc tcatcagcaa atgaaaaata
    36601 ttttgttctt tttatcagtt gttcttttta ttttttatct cttaattatg ttgctctttc
    36661 caatacgaca atgcttttca ttcctctaga tatcgccgtg tacatttgtc tgcgtcttct
    36721 ttgctcatct ccatcgtttt caaatggata taagattaca tgatcaaatt ccagtccttt
    36781 tgctagactc aaaggaatga tttggcagtt ttctaatcca tatgaatttt ttttaatcga
    36841 ttcttgtagc gtttgggttt cctcttctgt ttgggtgata actgccgctt tttctccttt
    36901 tagagaaacc aaaatctcag ctagtatttt caacaattct tcagaggatc gaaaagagcg
    36961 gtattcgggt tcttttcctt gcggtcggat cgatacgatg tcgatcttct cttgatccac
    37021 agcataggtt ttgaaaagct ctgtgattgc tccgctagaa cggtaactat ttctaagatc
    37081 ataccgatgg atcggcagat ggtagtcgtc gaaacaacgc ataatatcag caaaagtagt
    37141 ggaagaatta aagattgcct gattctcgtc acctactaaa gtaaagtgag tttttggaaa
    37201 taattcgatc aatagaccta attgtgccag ggtataatct tgtacttcat caatcaatag
    37261 atagcgaaat gctggtacat ttaccttttc aacaagtaaa tgacgaatag ctaatataat
    37321 gactgcttca tcaacagtac gtgtgggttg ccaagcataa gctgagccat atcgtttttc
    37381 ataaattctt tcaaacaact gatgctcatc cacccatgcc atttcttcga tttgtctggt
    37441 tatttttcga tatttttttt gtaaaagttt ccttgcataa gctacaatac tttgttccga
    37501 atcatcagaa atcaatttac cgaataattc caactgccta tcttctgtca acgagagtac
    37561 ctgattctgc acagcaggac tttttgcttg tttcaaaaga tgattcttcc attcgctcat
    37621 cagtgccttt ttcgttgctt gaagcctatc gatcaattta ggatgagcag gaactttctc
    37681 atatattttt tcgatcgttt ttttagaaag gactgttttt ccatttttag taagtccacg
    37741 gataaaattc ggatgatcta aaaacaaagg atctgattgt tttagattat cgataaactt
    37801 tttgctacgc aaacgttctg tctgctccga tacattttct cccgtgatac gtttgaaata
    37861 agcctcttca ccttctattt cctctgctga aagctgtgaa accagctgta tgatggttag
    37921 attcagtgga tttctttcac ctaatgatgg taggacattc gaaatatagt cgataaaccg
    37981 atgattaggt gatagaatca gcaagtcatc ggatgtcatc gtatctcgat ataaatagag
    38041 cagatacgca atacgctgca tgatagcaga ggttttacca cttcctgcta cgccatttac
    38101 caagatattt tgacttttca catcccgaat gattgtgttt tgttccgatt ggatcgtagc
    38161 agtgatagcc ttcatttcat tggtctcatc ttggcctaag acttctaata atacgtcatc
    38221 ttgaatagct acagacgtat caaaaaactt gaccaaacga tctctttcca aaagaaattg
    38281 tcgtctttct ttaataaccg tatcgatttt attttgacga accgtataag aagatggacc
    38341 aatcatgtta ttgtaaaaaa gttcggcaat tggtgaacgc caatcataaa caagattttc
    38401 atctgcatca tctgtgaaat ttgctgtacc gatataaaag gattcttttg gctcattatc
    38461 cagaaagtct acaacgactt ttccaaagta gggacttttc aataaacgtt cgatctttgc
    38521 tagctgattt tctgcgtttt tctgtttgat attcatctga tcgatttctc tatttttcat
    38581 ttcaatcatc gaaaaagtat ccaggttatc taagtaactg tcaaaattca atcgaagctc
    38641 gccagccatt tctttcaacg actggtttcc ttctattttt gccgtatcca tcgattcccg
    38701 cagttcgttt tttttatcaa ttagcttttg atacacgttc ttcagatatg cttcttctaa
    38761 ctgtttttgt gtgttgacca tacacattct cctctttttt taaagtggtg gaaccgatta
    38821 gtttacctct tttaagagtc gaatgcaagc tttttaacga gtatcatttg ttaggatata
    38881 tcagttcttc aggtcggaca gtttgatata aagaaaatgc accatcaagg ttttttacgt
    38941 ggtagccaga ctgcttcaag attctttccg ctagatagct acgtaatccg ctatgacagc
    39001 tgacgatata ttcttgttgg ctgtctaatt catttaatcg gtcccgaagt tcattcaaag
    39061 ggatatgttt ggcttccttg aatttgccct tttccaattc ttctgctgtt cgcacatcta
    39121 ataaaatttt tccttttgct agttctgtcg gcaattcatg ccattgtacg gtttcactaa
    39181 gcccttctgc aatgttcatt gctgcatatc ctagcatgtt tactggatct ttggctgagc
    39241 caaatggcgg tgcatacgtc aattctaatt ccggtaaatc gaagatcgtc aaatgccctt
    39301 tgattgctgt tgctaaaata tcgatccgtt tatccacacc ttttgcccca acaccttgtg
    39361 caccataaat ctcgccagtc tctggatgga agatcaactt cagtaaaata tctgttgctt
    39421 ctggataata gcttgcatga tcttttcctg atacatgaat gacttcaaaa gacagttcgt
    39481 tttctttggc tgttctttca cttaaaccgg tggatgcggc agtcattcca aacgttcgta
    39541 taattgctgt tccaataccg ccttgatttc ttcgagaaat tccggaaatc gtgtccgcaa
    39601 cttgtctacc ttgacgattg gctggtgaag caagagaaat aagtgcatct tttccagtga
    39661 tttgctgttt tacaacgata gcatccccca ccgcataaat atcaggaata ttcgtttgat
    39721 aacgttcgtc tactaggata cccccgcgta tgcctaattc gattccagcg gtcactgcta
    39781 gctggttatc aggacgaaca ccaatggata aaataactaa atcagcaggg atggtacgcc
    39841 catcatccag tcgcaatcgt ttcccgtggt cttcaaatcc agcgacagca tgagaagtaa
    39901 tcacttctac tccttgatga gacaattctt tttctataaa agctgccatt tcttcatcca
    39961 gtgttggaag aatatgtggt gcttgttcga tcaccatgac ttctaaacct cttcttttta
    40021 ggttttctgc catttccaat ccgatgaatc ctgcaccaac gatcacggca cgctttggct
    40081 gtttttctaa tgcatgcatc actttatcga tatctggtac atttctaata gaaaaaacat
    40141 tgtcggcttc tgttatccct ggaatcgatg gaacaactgg ttttgcacca ggagataaaa
    40201 ccaatgcatc gtactgttca atgtgttttt gaccctcatg tacgacttct accgttttgt
    40261 tttcgggaaa gatggctgtc acttcatgat ttggacgcac atctaaacaa aaacgagcgg
    40321 ataatgattc tggcgtttgg acaagaagat tttcccgttc actgatttct cccgaaagat
    40381 aataaggcaa gccgcaattt gcaaaagaaa catacggtcc tttttcaaaa acaacgattt
    40441 ctgcatcttc cattaatcgg cgaagccgtg tagcagcaga cattccacct gctacacctc
    40501 cgacaataac gattttcatc ttatttccct cctactgttc gatcaaacca ttgattcatg
    40561 ccaccacgta cattcactac atcataacca gatttcttta attctttagc tgcttgttta
    40621 ctcctcatcc ctgattgaca aatcacatag acggtctttt ctttgtctcc atcatatctg
    40681 tttatacttt gtaatggaac atttttagct ccttttatat gcccgccccg gtattctgca
    40741 ggtgttctaa catcaagtaa cgctggattt tccaaaagct tttcctttaa ttctgggact
    40801 gttatcgatt ttattgattg aaatagcaaa ttcattttct gcacctcatt tacattttta
    40861 taaatacctc atggggtata ttaaacagga gctttattaa tatgtcaacc agaatgactc
    40921 ttcatttttt tcactacttt ttatatttgc ataaaatacc gataaggggt attatctaat
    40981 tataaaaata gaggagaatg tgttatggag attgataata aaaatatcct gaaccgtttg
    41041 aaacgtacag agggacaaat tcgtggtatc caaaaaatga tcgaagacga aaaagaatgt
    41101 atggatgtca tcactcaatt aagcgctgtt cgttctagta ttgatcgcgt aatgggcatg
    41161 atcgttgcag ataatctgaa aaattgcttt gagaaacctg atagtaatcc agaagaacaa
    41221 gcggctaaac tagaacaagc gatcaagatg attattaaaa agtaaaggaa tgatttcaat
    41281 gaaagtcgtt ttccatattg atgaattaga aaaatggtca gaaacaggga aaaacgtaaa
    41341 aaacctgata aaagcttctc cagaaacgac gattgtcgta tctgtaaatg gcatcgcgat
    41401 taccggttat ctagactctg ccaatgcaga attcttagat ttgcaaggag tcgtttttca
    41461 cgcttgcgcc aatgctatgc gtgctaatca tatttcagaa agttctttac ctgaacaagt
    41521 aatcgttgta ccagcaggtg tccttgattt agttgaactg caatcccaag gttatgctta
    41581 tatcaagcct tagtcagtag aggttgcgac agaagtgatc agcttcaaga aatttcggct
    41641 tatttttcga agaagctact tctggaaaac cgtgaatcaa aggttgtgaa aacgctgtcc
    41701 tgcatcaagt aataagaaca gccaaacaaa aatagcttct catatttttc gtttggttgg
    41761 gcttattacc gcagatgcaa gcttttgaac accgtttaag gaagaggttg tgaaatcagc
    41821 ggtttgacct aagtattaga gaaaaaaacg ggaaaatagc tcctcatatt ttgccgtttt
    41881 ttgagctaat accgaaggtc agctgattga acaccgttta aggaagagat tgtgaaaaag
    41941 tcgcttagtt tcgagtatta agaaaaattt tgtgaaaatg gatttctaca tttttgcata
    42001 aatttggctt aataccgaga aactggcttt tgaataccgt ttaaggaaga ggttgtaaaa
    42061 tcagcggttt gacctgagta ttagagaaac aaacggaaaa atagctgctc atattttgcc
    42121 gttttttgag ctaataccga aggtcagctg attgaacacc gtttaccaag aggttgtgag
    42181 cctaccattt aactccgaat cacaagaaat aatttcaaaa acaacttctc ctgtttttgg
    42241 ttcggttggc ttattatcga gaagtagcta ctgggagtct atttatcaaa aaaaggaatg
    42301 cgacataggt cacacccctt ttttattttc tttgaaacat ctttcggtac tcgacagcat
    42361 acaagacaaa agattgtaaa agaccgtaag tgatgacggc aaaaatgact ctcacccaca
    42421 gcgttggtaa ttctgggaaa agcagcaaaa ggatcatgcc aacatagatg acagcagtcg
    42481 ctactttgcc ataccacttc gctccactta atttgatatt tttagatagc ccgattaatc
    42541 cagctacaaa cataaagcct tcttttatca agaatagacc aaacaacagc caaagccacg
    42601 gtcgatacca tgccatagac aaaatcagaa aaagttgtgt caatttatct gcaaacggat
    42661 caagcacctt ccctaagtct gttacctgat tatatctccg agcaatgacc ccgtctagat
    42721 aatcagacaa acctgagaca acaatgaccg ctcctgctat ataaaatgac tgtctcagca
    42781 caaaataaag ataaatcggc agcaaaaaaa tacggaatat cgataaaaga ttcggaatcg
    42841 tttgtatttc tttacgccag tctgtgctta atttcatttt atcgccctac ctcctcagca
    42901 ctcttttctt tttattttag cttacacggg gaataaaacc aatgatttca ctgtttttat
    42961 ttttctttac agacactgat attatgagct aatttgagat aatcacttgc tgttttcatc
    43021 gtttactctt ctttcttcct gtcgtttgcg catttctttt actagtactt tatgagcttt
    43081 ttttgatcct cgctctaggt cacgctgccg tttacgtgtt ttataatcga taaacagact
    43141 gtctaaatcg taacctgtcg ggtacagatc ttctgctgaa cgcaccagac gaacacgctg
    43201 acgaggcacg tggattattt ttttgtctaa atatacatca atcgtatctt cacctatatc
    43261 ttcataaact aacgcttctt tttggtattc attgacaaat atccgatcac cttttgcaaa
    43321 gagctgacgt tcttttttat tctccttcct atttgtaact gctgtcttag gaagaaattc
    43381 ttttttctgt gtccgatagg ctttttccgc caagtaacgc tctgcttgat ggatcaattt
    43441 catcgacata tccattttat gagcaatcca caaagcttgg ctttctcctg tttcttccaa
    43501 cccgcaactg atatttagga cgaagtgctt cccgatcgaa agccatagca gccggcacaa
    43561 aatcttcatg atctccggcg aatttcttga tttctccata atgggtcgtg gcaatgatca
    43621 atgccccttg ctcatacata gattccatga ttgcgatcgc tagtgcagcc ccttcatttg
    43681 gctctgttcc actgccaatc tcatctaaaa gtaccaacgt attccttttt atctttttca
    43741 aaatagcagc gatgttttgc atatgaccag aaaatgtact caacgcattt tctaaatttt
    43801 ggtggtcacc gacatcgacg aaaatctcat caaagacagc aagctctgtc ccttcttttg
    43861 ccggaacttg cataccgaac atcgccatca aagtcaataa accgactgtc ttcaacacga
    43921 ctgttttgcc tccggcattt gctccggtga taatcaagcc tcgatagtct ttaccgattt
    43981 caacatccaa tggtaccgca tgctcaggta aaaatggatg tctgccttgc ttgataatga
    44041 tatgttccga tttattgatt ctaggtgtgc ttccattgat ttctcggcta aattttgccc
    44101 gagcaaagat gatatctaac accgtgatcg tttcgatcaa taaatcgatc acttcttcgt
    44161 tttctgcgat agcaccagtc aatgccgcca ggacttgata ttcttcactg atttcttcag
    44221 cttttaacaa ctgatagtgt tcattcaatt tagaaatcac agttggttca ataaaaaccg
    44281 tcgttctttt atttgattca tcgataatcg ttccatctat tttattttta tagctggctt
    44341 tgataggaat cgtatagtat tcgccttttt gaacaatcat tgcttcttgg atcatttctt
    44401 tgtttttcgg atgacgcaag aatttcagta attttgactg gatttctttt tcgattagtt
    44461 gtaattgttt gcgtacttta cgcaaattac gtgacgcgtc gtcactgact ttattatttt
    44521 ttattttctg gtcaatcaac tcttctacat ttatcaaatc aggaagatgt ttgctataag
    44581 caaacaacaa gggtgtctgg tattgattct tatcaaaaaa ctttgtgatc atccgactgc
    44641 ttctaagaaa atccgcatat tcgatcaaat cggttggctg cagaatcaac ccttttttga
    44701 cttgttctgt cagtgcatcg atcctcggca accccataaa tggaacatgc tgactgcttt
    44761 ctaagatcaa gcgtgcttct cttgtttctt cttgacgatc caagacagtt tgtaggtttg
    44821 tcgagaccgt catatcgctg attcgttttt tgctatagtt tccaattgct cttgcttgga
    44881 tttccttttt gatccgatca aattgtaatt gactaatcat ttcgttgtcc atattctctc
    44941 cttttcttga agagatacct gtcccaaaat aaataagggc ctagagataa ataaaaggat
    45001 agaacacagc ttaaaaaagt catgtcctat ccttattaga atacaaagat attgttttcc
    45061 tgacaggtac cgtttcataa gcacaccaaa taaactttgt ttattggcta ttcgacttac
    45121 tgattagata ccagctacac tcacaaaaca taccccattc ttctaggtct tatttatttt
    45181 ccacttaact atagcaagac acattttggt tgtcaaactt tagtatgttt tatagattta
    45241 caccattaat gaatagacac ctaccgcgat aattgctccg atcattggac ctgcgattgg
    45301 tacccatgaa tatgcccaat ctgaagttcc tttattagct attggcaata ccgcatgtgc
    45361 taatcgagga ccaaagtccc gagcagggtt gattgcatat cctgttggcc ctcctaatga
    45421 aagaccgatg gctaagatca atccacctac agcgaatacg ttcgttccag gtgcaaattc
    45481 gttttgtcca aaagctagca acccaagaac taatacaaat gtaccaatta attctgtgat
    45541 cacatttgct ggataattcc gtatagcagg acctgttgca aacgttccta aaatcgcgct
    45601 ttcatctttc gttgcattcc aatgtggcaa ataagaaagc caaacaagaa tggcccctgc
    45661 aaaagctcct aaaacttgcg caatgatgaa aggaacgaca agattccaac taattgcccc
    45721 tgtcatcgcc atagctagag agactgcagg attcaaatga gctgggccca tgaatccaga
    45781 aatatagaca gccattgtta cagcgagtcc ccaaccaaat gcgatgacaa tccagccaga
    45841 agcctgtgct ttacttttgt ttaaattcac agccgcacac acaccatctc caagcaaaac
    45901 taggatcagt gtcccaataa actcccccat gatttgagtc atatcactgt tcatttattt
    45961 ctcccccttt agttcccgca gatctgattc tgcaatcaat gcttctaaac gtttagtctg
    46021 ttgcgccttc tcctcttctg tccattcaaa atatccagca attgcatcga tcacaggttg
    46081 cttgatctca tcaagctgat ctcgttcaaa caacagatga tttgtacgac gaatgagata
    46141 atcgcctggg gccaaaacca tttcttcttc taaaccataa cgtaaccgag ctgactcagc
    46201 gagactcaaa ccaggataag gtgccatttc ttttgctaat tcaaagatac gtcgggcatt
    46261 agtcccgtaa aaatcagcga tataagtagc atcttcttcc tctaaaccgg ctgctactcc
    46321 ttcttttgct aattctgtca ctgtttcttc taatttagtt ggatcgaagt ttccacctga
    46381 aatctgatat tttttagagt cgatttcttt cgtctctatt ccgtattctt cttttaataa
    46441 ttggcgtatc aatcgcaaag ctccttctgc catcttacgg taatcggtga ttttcccacc
    46501 agataaagtc agcaaaccat ctggttctct ttctaaagaa ctacctctgg aaatcgtaga
    46561 aggtgctttt tcatcacggc tgttttccaa atggttcaac acgtcttcta cttcagcacg
    46621 agaaactttg ttttccttat attcacttac tgtatcgaca actttattga agctcttgtc
    46681 tgaaatcgat ccattatctc caccattgta atcagaacca gaattaccaa tcaacagtgg
    46741 acgaagtcct gcccagcttg cttcgatatc attcaatgtg atatttgctt ctggatagcg
    46801 atgattgatc acatccaata gataatctac atcttcttgt gtgactttcg gatccgtaaa
    46861 atctccttgg taatccgtat ctgtcgtacc aaagtaagtc ttgttttctc ttggaatagc
    46921 aaaaaccatc cgcccatctt gctttcctgt atcgaagtat gtgggttgcg gtacaggcag
    46981 ttttttcgca tctacaacta aatggatccc tttagttgga cgcattttag gagagactgg
    47041 acgcgtaaaa ttcaagtttc gtactttatc tacccaagga ccactcgtat tgatcactaa
    47101 ttttgctttg atttcgatca cttcatctgt cagcaggtca cgagctttga cgccaacgat
    47161 ttgatcgcca tcatataaaa agccaaccgc tttcatttta cttactagat aagccccatc
    47221 ttcggcagcc tttttgatat tatcaatcac taaacgggca tcattgttgc ggaaatctag
    47281 atagacaccc gcgcctttta gcccttcttt tttcaaaaac ggttctcttt ccaatacttc
    47341 ttctggtgtc agcgtataat tctcatattt ggttcctgtc acatttgcca gtttgtcata
    47401 aaggtccatt gctactttga ccgagaacat attgaaggtt gttgctcctt cgccctcata
    47461 gattggcaaa agcattggat ctggttttgg gatgtgtggg gcaatacttt gtacgactgc
    47521 acgttcacca actgtgtcag ctactacttc cacatcaaat gtcttcagat aacgaatacc
    47581 gccatgaaca agtttggtcg agcgagagga agtcccttct gcaaaatcct gcatttcgat
    47641 caatcctgtt ttgattcctg atgctgctga ctggactgcc acaccggcac cagtgattcc
    47701 gccaccgatg atcaacagat ccaattcttc ttgctgcatt ttttgaatgc tatcttgtct
    47761 tgtcttgttt gaaaacatat ggatttcctc cttattcaaa tgcttgggta gcttttactg
    47821 cttttttcca accgttgtaa agtttttctc ggcgctcttc ctccatttga acttcaaata
    47881 gcttgccagc ttcataaaat tcgcggatct cgtctgtatc tttccaataa ccgacagcta
    47941 atcctgctaa aaatgctgcc cctagcgccg ttgtttccaa gttttctgct cgttggatcg
    48001 gtacattcaa gatatctgtt tggaattgca tcagatattc attgtttgct gcaccgccat
    48061 ctactttcaa tacaggaatc ttgattccag tgtcatcttg catcgtatcg atgatatctc
    48121 tcacttgata agcaatcgac tgtaaagtag ctttaatgat atcttctttt gtcgtaccac
    48181 gtgtcaagcc aaacatagcc cctcgtgctg cctgatccca ataaggagca cctagcccaa
    48241 cgaatgcagg aacaacataa acctcatctt cgcttgtaga gcgtttcgct gcgtcttctg
    48301 aatcgctagc tttttgcaac atttgaagtc catctctcag ccattgaatc gaagaaccag
    48361 ccacaaaaat acttccttct aaagcatagt aaacctttcc atttatgccg taaccaattg
    48421 tcgtcaataa attatttttg gataattgcg gtttttcacc ggtattcatg acaataaatg
    48481 aacctgtacc ataagtattc ttgaccatgc ctggttcgaa tgccatttgt ccgaataatg
    48541 cggcttgctg gtctcctgcc atccctgaaa ttggtgcttc gcttccataa aaatgataac
    48601 cttgcgtata accataaact tctgagttag aagtgacttt tggtaacatc actcgaggaa
    48661 tatttagtaa atctaaaatc tcctgatccc aatctagctg atggatattg aacaacatcg
    48721 tccgactggc attcgagtaa tcagtaacat gtgcttgtcc atcggtcagt ttccatacta
    48781 accaagaatc gatcgttcca aacatcaatt cgcctttttc agctcgttct tgcgcgcctt
    48841 ctacatgatc aagaatccag cgtatcttcg ttgctgagaa ataggcatcg atcactaacc
    48901 ctgttttttc gtggaaaaat tcttgatagc cttcattttt taagttatct gcaattccag
    48961 ctgactgtct ggattgccaa acaactgcat gatagattgg acgtcctgta tctttttccc
    49021 atattactgt tgtttcacgc tggttcgtta tgccaatccc agcaatctga tttggtttga
    49081 tccctgattc gatgaacgct ccggcaataa ctgactgtac agaattccag atttcatttg
    49141 catcatgttc cacccaactt tcttgcggga aatattgcgt gaactctttt tgagaactgc
    49201 cgatgtgtct tcctttcttg tcaaagataa ttgctcgtga gctagttgta ccttggtcaa
    49261 tcgccatgat atacgttgat tctgtcattg tgattccctc cattatatgc aaacgctttc
    49321 tttaactact cttatcatac tactgtttta aaaaaagaaa ctgtcaaaat tttattcttt
    49381 ttttcttttt ttgacagttt tttattatga agctattttt taatcaattc ttttcttttt
    49441 tcagcgtctc tattcttctt ttcaatcgaa taatgtcgta aggtgacgca aattctgaca
    49501 gataatattc acactgtttt ttgtttctct ggcaaaatgt gatcaccaaa tcatattctt
    49561 taccttcttc ataacttcca atctcaatac cgccgattcc cctcagttct ctgatcagat
    49621 attgttgaaa agcaatacga taaatcggca gactttctaa atcgattcca atcactactg
    49681 gttttgcaat ataaaaatcg atcatcaaaa gaacattggc atactggatc atcaggtaac
    49741 taagctcact atcttcagct cttttcctcg gcaattgctg caccgctgtt tcctgtaatt
    49801 tcgccagtaa ctgtgttaag gaatgcccga gcattttctg ctgctgttcc aaaagccgat
    49861 cacgctcata gacttcgatc tttccaacaa agaaaaacca ttcattgttg atctgggaaa
    49921 tttggtagcc tactgccttt tcttctttga ttttcaaacg acgaggacga taatgccata
    49981 acatcgtttc ccgaatgtaa gtatctaaaa cagcggttgg taactttttg ctccgtgtca
    50041 aatcatactg ataaaatatt tcttcgtcta ctatcgaaaa agaaacaaaa aagctgtaaa
    50101 acatcattgt ttcgtataca ttcagttctg ctgctgttcg actaagatgc atcacgatga
    50161 ttggatcgat tgcttgataa agccggtccg actgatagag taatttcttt tctttcaaag
    50221 ttgcgtacgt acttttttca ttcaatagtc tttttttcgt aatcccgagc cagcaagcaa
    50281 tctgtgcttc tgctgatgcc gtaaacgttg tttctaatac acggtccaat cctagaatga
    50341 acggtctttt ttctggtgta ttttgcaaaa aaagcggtcg ctgatcttcc gggatatatt
    50401 ggaatagttc ataataaaaa tatcgtatct gtagctcttc tccgtataat tgaccgtttt
    50461 tgatttgtaa tccaaattcc tctaagagct ggttcaattc tttgatcttt cgaaaaacag
    50521 aagactcact gatattaaac gctgtcgcta atcgaacgat ggatacttgc tgatgttcta
    50581 ataaatagac gagcatctta aacttcaagc tttcctgcaa taaaaacaat agaatttttt
    50641 ccaaacttac atcttcgtcc aacacaagca gcgcctgata ctcatttcgc tgtacttcta
    50701 cttttttttc catcattcgg ccaatcaatt caatatcttc caaatattga tcaaacgagg
    50761 cttttgacag ttggacatgc tctctcaaac cattgataga ggctgttccc ccttgcagaa
    50821 caaggtttcg caaaatcagg atctgtaact gctcttttct ttctaataat gcttcaatct
    50881 tcataggcag tattcgccac ctttgaccac accatatctg gcacacggta ttctggctgg
    50941 aaaaatagct catgttcttc taactgttca aacgtccatc cttcttctac tgcaattgtc
    51001 agttggtcaa gaaggtggaa catctctttt ttgctttgga gctgtgctcc aagaatcttt
    51061 ttttcagaat caaatagaaa tttgagttta actttgcttt gatttattgc tgtaagcttg
    51121 tagtctacgt atcctgtttc aattttttgg ggataaaaaa tgctctcttc ttctgtcaaa
    51181 cctacgcttc ctaagaaata gccaaaccac tgattgccga ctggacgata ggttccctga
    51241 tcctttgtct gtgagccact aattgtcttg ctgacatttc gtgctgtacg gacagcgtta
    51301 tttactagag aaacatacat tttttcattt gttggacgaa aagttacttg gatcgcatcg
    51361 ccaatcgcat aaacgtcttt ttgagacgtt tgcaagtagt catctaccca gatcgttcca
    51421 tcatcattca atgttaattg ttcttcccac atctgattgt cgggacgaga atgattagcc
    51481 agcaaaacaa gatcatagtt ctcctttctt ttttccgtct ctacaatagc ggtttcattt
    51541 tcggtcaaag acacaacttg ttcttctaaa aaaagtgaaa gcccttgatt tttcatttcc
    51601 tttactaacg gttctgtcat ttcaggatct agataacgaa aaagaattga ctttcggctt
    51661 tcgtaaagat ggatttgttt ttttcttgat gccaaccctt cagctatttc gattcctgct
    51721 tgtcctgcac caataattgc aattttcttt gcattcatga tcttttgctg aagagccgtt
    51781 acgttttgta tctttttaac tgggtgaata agcgttgatt ctgcagaaat atttcgaaac
    51841 ttttgatttg aaccagtcgc tagaatcaaa cgatcaaaat ccaatttttt tcctcctgct
    51901 aaaacgactt ttttttcttt caatcctatt actgtctttt ctgtgtaaac atggattcga
    51961 tagcggtcag tcagttcttc tttcgtgatc caagaaagtt gtttttcact ggtaaccttt
    52021 ccttttaata tcaaattgaa cccgctggga atccatccta acttcgattg cttttcaatc
    52081 aaatatattt cacttgttgg catcaattgg cgaagataaa tagccgcatg aatccctgca
    52141 aacgacccgc cgacaattac aatgttcatc tgcattcctc tttcttataa ggtgttctac
    52201 tgctaacttc tcaatcagaa aacacagtat tcataactcg ctttcaacct tatgatacat
    52261 agcgatgcag cagaatcaac cctctccatc ataccgtgtt ctaggtctgc ttctcaataa
    52321 tgtactagtg gacctaattg aagagtatca tttctgaaga gatgtttcaa aaaatgtact
    52381 cttataaaag aaaaaaactc gccttttacg tacctctgtc caaataggaa acagaaaaga
    52441 acgaaaagac gagttttagc gtgtgtaatg taatagttag aatagacaca tcatttattt
    52501 ttaattcttt aatgcttcaa caactgcttc gcctaattga tgagcagatt gaggattttg
    52561 ccctgtaaga agccgcccat caatttgaac cacttctgaa aaagctgctc cagactgata
    52621 gtttgctcct ttttctttca aagcatcttc tgctaagaat ggtacttcat tcgttgtacc
    52681 atttgcttcc tcttcttcat tactgaaccc agtcactgta cgtccagcta aaatagattt
    52741 tccagactca tctgtaactg gcaacaatcc tacaacaccg tgacaaacag ctgagaccag
    52801 cccttcattt cgatagattt gtgaagcgac tttcccaaga tctattgctt ctggaaaatc
    52861 ccacattgtt ccgtggccac cagcataata aaccgctgca taatcatttg catccacatc
    52921 atcaggacgt aaggtatttc ccaaggcccg atttctgaaa tcttcatctt cataataggc
    52981 ccaatcgatt tcatccatat tcaaaacact ttgcggttct aaaggtacat atccgccttt
    53041 aggactgaca aaatctgcat cgatcccatt ttttactaat acatcataaa aatgagtcag
    53101 ttcacttaac cacaaacctg taggacgctc gatcttttcg tacttttcta catttgttaa
    53161 tacgatcaat actttcattt tcccatcctc tttctataaa aattgcgtta ttgataacgt
    53221 gctttcaaga aattatataa tgggcttggc aaataaagct ctttatatgc tttttcaaaa
    53281 ggtttcgtta caaattcatc ctcacggttt tccaataatt tctctgccca gtcaggatcg
    53341 acgatcattt gctgtccaat tgctgcaagt tctgcatatt tcaatacctg ctctacatct
    53401 tcgcgattgc ggatcccacc gacaccaact aaagggatct ttccttgaat cgtgttatgg
    53461 accacttcaa gaatcgattt atcgttgtat ttatcagaac gagctattcg atcatacata
    53521 tttaatgaaa catgcagata atctagtttt gactcacgta atcgttcaag aagccagatc
    53581 gtgtcttcaa aacggatacc tggtgtttca tattcttctg gtgagaaacg ataccctacg
    53641 atgaatggtt ttttagcata ttgttcaacc gctgagaaaa ccgttgttaa taattcttca
    53701 ataaaacgat aacgattttc caagctaccg ccccattgat cctctcgtct attcgaatgc
    53761 ggagagaaaa attgttggat caaatacgta tttgctccat gcaactcgat tccatcaaat
    53821 cctgattcaa tcgctctacg tgtggctttg ccaaatgctt ggattgtttc aacgatttct
    53881 tcttcactca ttgctcgtgg tgtttccgca tcaggacgtt ttgctgcaac tgcacttgca
    53941 gatacaggct gttctccaga taaagttgct cgacttgtca ttcgtccacc gtggaaaatc
    54001 tgaataatcg cttttgcgcc ttctccttgg attgctttcg ctagctcact taatcgagga
    54061 atcatttcat catgagcgat gctgagttca cctggccagc cttttccgat atcttggaca
    54121 tttgcagcac cagtaataac agcaccaaga cctttagaac gttgtttata ataagtgatc
    54181 tcatcttcgg tgatcactcc attgaaaaag ctgagttgtg tcgtcatagg cgacagcatc
    54241 aatcggttct tcaattgaac tcctgaaggt aaagtaattg attgatcaaa ttgtgacatt
    54301 gtcattcctc ccataattcg ctctgattaa cctatcgaga atcatctatc attaaaccac
    54361 tcgattagtt gtacatgcaa ctaatttgct taaaaaattt tatttttttt gtaacttatc
    54421 tgttgcatca ttcattgtct gggctaattc tttacttgct tcatttccca aaactgcttt
    54481 gtatgactga tgaagttctt cccagctacc atcgacttcc ttagcaaatt ggcgtccttg
    54541 ttctgtaaga taaactaatg acaagcgacc ttcgctaact gttttgacgt atcctttata
    54601 ttctaatttt tcaacaaaac gagcaatcgt tgatggggcg gaatagagca tttgtgcaat
    54661 atctttttgt ggtattccat ctttttcttt taatatcaat aaaataaaac cataagttgg
    54721 tgccagacct gtccttctaa acgcttcatc agctaattta ttcaacatgc gatctagctt
    54781 tttcacgcta aagaaaagac attcatctaa cgctttttca attggctttt ccatttcatc
    54841 ccctccattg gcgtacatat catagtatga tttttatttt ttgtcaaaaa acacggaata
    54901 atgtccgcct cctctgtcta gatttgaaaa aaagaagtag ccatcttcaa agaatttcgg
    54961 cttgttttcg acaaaactcc ttctggaaca ccgtgaatca gaggttgtga aaaagtcgtt
    55021 tagttttgag tatgaagaaa aattttgtga aaatggcttt ccacattttt gcataaattt
    55081 ggcttaatac cgaaaaactg gcttttgaac accgtttata tcagaggttg tgaaaaagcc
    55141 gtcctgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt ttgtcgtttt
    55201 ttgagctaat gccgatggtc agctgattgt acaccgttta ttgagaggtc gtgagcctgc
    55261 cgttgaactc cgagtcacaa ggagcaattt caaaaaacag cttctcatgt tttatgacta
    55321 tggtgacttg tgatcgagga gttggcagga gaatactgtt tattcgtaaa gaaggggctg
    55381 tgacaagact tttgtcacag tcccttattt ccttttatta taggatttcg ccatttgatt
    55441 ggatgacttg tctgtaccaa tcaaatgatt ttttctttaa ccgtttcttt gtgccattcc
    55501 cttcgtcatc ttgatcaaca tagatatatc cataacgttt tgacatttgt gaagtagaag
    55561 cgctgacgat atcaatgcag ccccacgacg tataaccaaa taaatctact ccatctttga
    55621 tagcttcctt catctgctca atatgctgct tcaaatagtc aatgcggtaa tcgtcttgaa
    55681 cggttccatc ttcttctact ttgtctatag ctccgagtcc gttttcagct atgaacagtg
    55741 gtttttgata cctatcatat aattgattca aagcaattct caaaccctta ggatcaatct
    55801 gccagcccca ttcacttgat ggaagatacg gatttttaat tcctccagtt attaagtttc
    55861 cttggacccc ttcccaattt tctggatgag cactgactgc actagacatg tagtagctaa
    55921 aagaaacaaa atcaacaggg taggctgcta agatttcttc atcacctact tctattttta
    55981 agttgacacc tttttcttca aacattcgtt gcgtatacgc tggataatat cctcttgctt
    56041 gaacatcact aaagaacaaa gaagttcttt gctgctcaat tgttttttga atatcatccg
    56101 gatcacaaga atacggaaca agaagctgat agctgatcat acaaccgact tgtgaacctt
    56161 tgataatttc atgacaagct tttgtagcta aagcacttgc tataaactga tggtgtgcac
    56221 cttggtattt cgcttgttcc aaatggggat ggttttcttc aattactcct acgctaacaa
    56281 aagggtgatg ttttacacag ttgatctcat tgaaagtcat ccaatatttt actttatttt
    56341 tatagcgttt gaatactgtt tcagcgaaac gaacgtaaaa ctgaataagc tttcgattag
    56401 gccatccacc atattctgta accaaatata acggcatttc ataatgggaa agagaaacga
    56461 ctggctcaat cccatatttt agacattcgt caaacacttg atcataaaaa aataatcccg
    56521 cttcattggg tgtttcttca tcaccatgag gaaaaattct tgtccatgcg atagacatcc
    56581 gatagcattt aaaacccatt tcagcaaata aacggatgtc ttctttaaag tgatgataga
    56641 aatcatttcc gtgtctttta ggataataat acttgctgtt gggatcctgc gccgctttta
    56701 cttgctgatg cgtcatcata tgccattgat ctgtccattt ttctttaggt aaatcgctgt
    56761 cgaatgtata cacatcagac acagataatc ctttttcatc tacatcccat gcaccttcac
    56821 attgattggc cgctgtcgct ccgccccata aaaatccttc tggaaatttt ttcatatcga
    56881 tccccctaaa cttgctagtt ttcttgtttg attatttttc ttatgactag taatgatatt
    56941 tttgaatcta ctactatttg taacaataac cattgtggtc ggatcatatc cctctttgat
    57001 taattcttgc aaatctactt ccatcaataa atcgccttta cgtacttttt ttccatcaga
    57061 tactgcactt tgaaagtatt tgccatttaa attcactgta tcaataccga tatggatcag
    57121 tatctctgct ccttcttcac tgactacccc aattgcatgt ttcgttggaa aaactgttga
    57181 aacttccccg tttacagaac tgtagatttt tccgtccgtt ggaatgatcg caaacccttc
    57241 tcctaaagat ccactagcaa atgttggatc gtttacttca gataaatcaa ttatttcacc
    57301 tgctgcagga gtacttaaca ctatatcctt tgaggattct tcttcgattt catccttgta
    57361 gccgaaaaga aaagttagca tacaggaact gatcatcgct aagaaataac tagcaactag
    57421 ccaaacaaat ccttcaccaa tataaatcgg gaaagacaaa atacttcttg tagcaactgc
    57481 caaagcaccg gctcctgcgg caccagctac tccaccaaat atagctccac atatacaagc
    57541 aatgtaaaat ggtcgtttat atttaagagt cacaccataa acagcaggtt cagtgattcc
    57601 aaataatgct gtgataaatg cagataaaga taaacttttt actttcttat ttttcgtttt
    57661 caaaaatacc ccaagtactg ctcctgcttg cgcagctacg gcagtcatac atgctggacc
    57721 tagcgtatca cgaccgtaga aagaaagatt gttggtcatt actggtacaa gtccccaatg
    57781 taacccaaaa atcactaaca cttgccaaaa tccgccgata acagcaccag ataaaacagg
    57841 gctaaagtta taaacagcta aatatccagc tgcaatcagc tgacttgcat aatctgcaat
    57901 tggacctaca actaataaaa taattgggac catcacgatg atacaaatga atggtgtcaa
    57961 taaatttcga atactttcgt gcaagctttt gcgaatctta ggctcaatat aagaaagaac
    58021 ccatacagct aaaattgctg gaataaccgt acttgtatac cttgctagaa tcacgggcat
    58081 ccctagaaat cgcaaggtta tgctatcact atatgcactg acaatcgtag gataaacgag
    58141 agctgctgca ataaccatag cgatgaaacg atctgtattg aacttttttg cagcagtata
    58201 tgccaaaaat ataggcaaga aatagaaaaa tgcatcagct gctgcattca aaatgatata
    58261 agttcctgat tcagtagtta ataaattcaa actcgtacat aaggcgagta ctcctttgat
    58321 caaaccactt cctgccaaga cgcctaaagt cggggcaaaa acagcggcga tcatgtctat
    58381 aaaagagttt aaaatgcctt ttttctcagt tcctctcttt ccactagatg catcatcttc
    58441 tagtttcatt tgtttggata atacgtcata cacttcattt actgcatttc ctactacgac
    58501 ttgaaacatt cctccagctt cgactacagt gatcacacct tctagttgct ctaccttctc
    58561 cttatctgcc ttcttattat cttttagggt aaagcgtaac cttgttgcac aatggtaaac
    58621 attgctgaca ttttcttcgc ctccgacaaa tcggacaata tctttcgcta attgtgaata
    58681 gtccattttt acttccccct tgttaattaa tgccgtagca atccttctta caagataagt
    58741 atagttctta gaaaacggtt tctccattca attagtaccc cttctaatag cgaacgaaac
    58801 tgtacaatag tgtgtatggt ttacttagcc gagcaaatca ctcactgctt gaaagaaaac
    58861 aagtatatcg tttctcttat agtcaaagga gacaaaaaaa acacgcttga tcttcctttg
    58921 ctgatgtata agtggtatct caagctgata ctctgtgatt tttgtttcta cttggctttt
    58981 gataagacag cacaacaaag tctcggcatt taacggaagc ataactaggt cagaactagg
    59041 agagattagt tgctgaatgg aatctatctt tttatggatt tttatttgat tttcttcttt
    59101 gtagtaatga tcaagcagtt ttgttttctt tttttcttca actatggtca gcttttcacg
    59161 caaaatctga taaatctccc aagattcaaa ctcatctaga acactaggta gataaatcaa
    59221 atcatcccac tcaaaaataa gctcttgctc agtagtcaaa attgcatcat attccgttat
    59281 tttgtttgat tgatttttga aaagatacac tggttctatc cggcattctt tgatccacat
    59341 gttcatactt tgttgaatct gtttttttag tgtattcaaa atactaattg gctggttact
    59401 aacaatcagt atctcccctt gttttcgaaa aggattcaac gcttcggcaa gatacaaaac
    59461 aaaataagcg ctttcagcta aattgggacg taattgaaaa tgtattggga agaaacgccg
    59521 aattaaataa atttctaaag gataacggga gatgatcttt tgtacaaaat gattcatggt
    59581 attatgtccg gcatccatcc tcgttttcat ttgtttgata tgggttagca aaaattctgt
    59641 ttcatggaac aataacgaaa caggaagatc taaaaaacga ataatcgttt gctcaaatgc
    59701 tcttagattc ttctctattt ctttgttttt ttcatcatta atcatcaaat aatttaactc
    59761 taatagtcga ttttcaattg cttgtttttc ttgattggaa aaagaatagg gtagttctga
    59821 tgataacttt tttgtgaggg tctctaccat cggaataaat aatgtatacc tgtttgtttt
    59881 ttctaaaagt tcttctcttc gaagaatggt caaaacgaga taccgagaaa atcgtatgaa
    59941 gtcctctcct gaaacaatat aattatatga tataagaacc tcttttaatg tcttttggac
    60001 agtcggcatg atattggaaa aaattgtact gatttgttga ggaaaccttg cgtgttggat
    60061 caccgtttct gttccaacaa gagataagaa aattcttttt gaattttctt cagcaatgat
    60121 ttttagtcct tttgtcgacg aaacttccag ttctaattta ggattgcgct cgatccaacg
    60181 caaaatcgtt tttatttgta atgatacggc tgtttttgaa agaaagaaaa tgtctgctat
    60241 cttttgcata ctgacatacc ctttttgaaa caataagtac gtcacaatag ttgaagctcg
    60301 gaaatccatg ctggaataga ttttatgttt cgtcacctct tgtatgattt gctgtttagt
    60361 ttcagattca attgattcta aaaaataacc tgaacgttta tttgactgga taatgatttt
    60421 cttctcgtag atagcaagca tatttttgat ttcagtttgg atcgttttct tgttggtacc
    60481 taaagcttca gctaattctt cgcttgttat ccaatgattc ttatttctta atactacaag
    60541 aatttggagt tgtcgtttat ttaagtccat ttgcttacac ctcctctttg ttataaacat
    60601 acaggaaaaa cctctcaaat gacaatagtc acttgcagag gtttaaaaat catttgaaga
    60661 aagatctata ttcaaggttt ttaccattag actggataat ttgtttataa tattcaaaac
    60721 tatctttttt caatctccta aagcttccgc tcccatcatt ttgtctatcc acataaataa
    60781 agccatatcg cttcctcatt tcccctgttc ctgccgatac gatatcgatt ggtccccacc
    60841 ataagtaacc aatgatttgg caaccatctt ttattgcctc agcaatttcc tgaagatgta
    60901 tttttagata ctcacaacgt tttggatcgt ggattcgatt caattcatct ggtgcttcat
    60961 ctagtccaat gccattttca actatgaata atggtaattc ataacggtct gtcaattcat
    61021 tcatgacata acgaaaccct agaggatcaa ttggccaact ccaaggttcg ggagattttt
    61081 ccttcaaaaa gggattatcg aaaccatttg ctccgccagt atctacgcgc atttctgctt
    61141 cttttttata gacagcgcta cgataataac taaatgcaat ataatctgcc gtgttagctt
    61201 gcaagcactg ttcgtctcca tctaacatta ctggtgcaca gtcttcttcc ttccatgtcc
    61261 tgtaaatata agctggataa tgccctcggc acatgacatc ggagaaaaac catgaattgc
    61321 gtttaaattg cagtgaacca aatacattct ctggatcaca gtcatatgca taagtcgcta
    61381 atgcagaaaa gctacacata atacccatct tagcatttgg atcgattttc tttaataatt
    61441 gagtagcacg ggcgttcgct agaaacatat gatgacaggc ttgataaatc actttttttg
    61501 ttagtgtagc aatgggttca agtttatctc tagcagggaa tgtaaccaat ccagcagctg
    61561 cataaggcat acgaaaagca ttattgatct cattaaaggt catccaatat ttcactttcc
    61621 cttggtagcg ttcaaagacg gtctgcgcat aaaattcaaa aaagtcgatt aattttcgat
    61681 tttgccaccc cccatactct cctaccaatg ctaagggggt ttcataatga ctaagagtaa
    61741 ttactggctc gatatcatat cgatttaatg tattgattag tctgtcataa aatacgagac
    61801 cagcctcatt tggcttctgt tcgtctcctc ttggaaatat tcgtgcccat gagatgcttg
    61861 ttcgaaaagc ttttaaacct aactccttca gtaaacgaat atcctcttca aatcgatgat
    61921 aaaaatcaat cgcttcatga gaaagataat ggagtgattc gtctaaagca atctcccaaa
    61981 tctttttttc ttcattccac tgaatactag gatgctggtt catgatcccg ataagcgtat
    62041 ctgtcacatt aggtaatttg ccgtcttcca accatgcacc ttcacattga ttagcagcta
    62101 ctgctccgcc ccataaaaaa ttttctggaa atatttcctg atccataact atctctcctc
    62161 gctatcaaca atttcttact tgaagtatag ctcgattcat caaaacaaga tattctaact
    62221 atttcggcag aagagaagaa aaaaattgaa tgctactctt catttttaat atttatatat
    62281 aacaaataca taagacgatc cccgaaagaa aacactcgtt aaccatctaa gcaaacgatt
    62341 tattttactt ccaacacaaa tgcttcataa ggtcgtaaat caactttgcc gtctggtaac
    62401 tgtttcagag gataatttga cacaataacc cttaaagctt cacgtggaat agtgaacgtc
    62461 tgcttttcac tggacatatt acaaataacg agccattgct ggtcttcata tatgcgagaa
    62521 taggcaaaga catgctcagg cgtcttttcc actaattcat agtctcccca gacgatgatg
    62581 tcatgttttc tacgcaaatc gatcaatttc ttgtacatat aaaaaacaga atcttgatct
    62641 gctaacgctt cttctgcatt gatttcttta taatttggat tgactcgaag ccatggaatt
    62701 ccagtagtaa acccagcatg ttcacgggcg ttccattgca taggcgtcct agcattgtct
    62761 cttcctttcg ccttgattga ttccaagatt tcctcttttg taaatccaga agaaatcctt
    62821 tcgttataca tattgattgt ctcaatatct tttgcttccg cgatatcatc gattgggcaa
    62881 ttcgtcatgc ctaactcttc tccttgatag atataagggg tgcctttcat catatggagc
    62941 aagatagcaa acatcttggc actttctttt cgatacacat cgtcatttcc ccaacgagaa
    63001 acaattcgcg gaagatcgtg attattccaa aataaactat tccatccttc atcacctaaa
    63061 gatgtttgcc atttggataa tacttttttc agttcagaga tactcaaggg tttcaaatcc
    63121 catttgtctt tgccttcttg ctgatctaat cctatgtgtt cgaattggaa gaccatggat
    63181 aattcatttc ttttaggatt ggaataaagt ttagcgattt cggtagttgc tccccatgtt
    63241 tcgccaacag tcatcagatt tttgtcacca aaagttgctt gattcatttc ctgaagatac
    63301 tcatgcagtt taggtccatt acttgtgatt tctttatccg gttctttgcc aatcatatcg
    63361 atcacgtcca tacgaaagcc cccaatacct ttatcgatcc agaaattcat catttgataa
    63421 atctcttggc gaacctgttt atttttccaa ttcaaatcag gttgacgctt gctatacaag
    63481 tgcagaaaat attgccccgt tttttcatcc aactgccaag cagaaccact gaatattgag
    63541 cgcaatctat taggctcttt tccattgacc ggatcacgcc aaatataata gtcccgataa
    63601 ggattttctt tatttttacg ggcctcaatg aaccacggat gttcatcaga agtatgattc
    63661 accaccagat ccatgatgat acggatattt cttttctttg cttcttcaat cagttcttcc
    63721 atttcttcca tcgtaccgaa ttctgccatg attgcttgat aattactgat atcataccca
    63781 ttgtcatcat tcggagactc gtatactgga gaaagccaaa ttgcatcaat acctaaatac
    63841 gccagataat ccaacctgga aataatcccc cgcaaatctc caataccatc ttgatttgaa
    63901 tcttgaaaac ttcttggata gatttgataa acaactgaat ggtgccacca tttttgttcc
    63961 atgattttcc tcctataaat ggatgtttct attttttgct taatcattta ttttagtctc
    64021 tctcactaaa aattgtaacg ctttcaaata gctattgcac cttgttatcg gtaacagaat
    64081 aaaacaaaaa aacagctgag gaaattccct caactgtttt ttgaaaggat tgatttatgc
    64141 agggaagaat gctgatttca caacttcttt ataaacggtg ttcactcagc tgtcccttgg
    64201 tattagctca aaaaacggca aaatataaga aactattttt tcgttttttt ctctaatact
    64261 caggccagaa cgctgatttc acaacctctt tatttcacat tcaatatcca catgaatccc
    64321 acaaatacaa agaacagacc atacatgatt ggagatactt cttttcctct tttagctgct
    64381 aacatggtaa ttggatagaa gataaaacct aatgcaatcc catctgaaat actataagtc
    64441 aaaggcatgc cgatcaagat caagaatgaa gggatcgcaa tctctaagtt tccccattcg
    64501 atttgtcgca aagattgtgc catcaatact cctaccataa tcaatgctgg tgcagttact
    64561 tgtgaagtaa caactgatag taatggagaa aagaacaagc ctaacaagaa gaaaatccct
    64621 gtagtaatag ctgtgatacc tgaacgtcct ccaacggcga taccagctga tgattctaca
    64681 aatgcaccaa caggagaagt accaaataag gaacccgcaa gcatagctgt tgaatcagaa
    64741 gctaaagctt tccctacacg aggcatcttg ttgtctttca tgaaacctgc ttggtttgct
    64801 aatccaacta aagttcctgc tgtatcaaag aaagtcacaa gcaagaatgt cagcactacg
    64861 acccacattt gaagagaatt gatgtcccct acatgtttta atgcaactaa aaatgttggt
    64921 ttcaaacttg gtgctgcggc aacaatttca gaaggcattg gaatcaaacc tgtgaccaga
    64981 cctaaaatcg ttgtagctgc catcccgatg aagatgccac ctggtacacg ccgaacaagc
    65041 aagatagcag ttacgactaa tccaaaaatc gtcaaccaag tagaaccaac gttgagtgat
    65101 cctaatccta ctaatgtaga ttcattcgaa acgatgatcc caccttcgct cagaccaagg
    65161 aaagcgataa atagaccgat accgccagaa atcgcatatt tcaaatctgc tgggatcgca
    65221 tcaatgatca tttcccgcag cttgaagatt gtgatcaaaa taaaaatcaa agaagcaacg
    65281 aatacgccgg ctaatgctgt ttcccatgga atccccattc ctaaacaaac agaataagca
    65341 aaaaaagcat tgatcccaag agcaggtgcc gttccaattg gataacgggc taataccccc
    65401 attaaaacac agccgatcgc actggctaat gcagtcgcag taaacactgc tccttcatcc
    65461 attccagaag cacctaatac agttggattt acaaataaga tataagccat tgagataaat
    65521 gttgtaaatc ctgccagtac ctcacgtttt accgtggtgt tcaatttttc tatttcgaag
    65581 taggaaagta ttttttcctt catcttccat ccccctaaat ccgaacatta taaataaagt
    65641 ccgttaaaat ttcgatttat taataaaaca acgtgtttta tcatatacta aaacaaaaca
    65701 taagtaaaca aaaaattcgg attttaagca aaatccgaac gttccatctg attaaatccc
    65761 tttatctcaa agttcatgaa cattcacttt ggattacaag aatttcttta ttgtgttaat
    65821 aaagtttctt cattctagtc tcaaaaatca atagtgtgat ttgattttac catttcgttt
    65881 ctgttcttct ttgatgaatt cttttgtatc gacaggattc agattattta gtccgccaaa
    65941 acctgtatcg accatttttc cccagccttt tgtcttcttt tttcctgatt tgagattctt
    66001 tgctcgaagc ttctcactat gttttgctcg ccgatacttc aaataacctt ctaatcttcc
    66061 cattagatcc actgtttttc ctccttttta ttcaatcaga cgactcagct tttcctataa
    66121 caaaataatt gccttcaggg tcagaaaaat tgaaagtcaa gatgccattg ttatctgtga
    66181 tttctcctgg ttcttccatg ttctcgtaga tagtttcaaa ttcatccgta aaaaatacta
    66241 aagaaggcgg tggtcctaat acctctggtg aaaacttctg cacaaatact tttgggaata
    66301 cgcctaattc taattctttt gagatgctga gtacaatact cttaaattct tctggcaatt
    66361 cgattgtttc agaaatttct gcaccaattt tttctacaaa gaatcggcaa atcatctcta
    66421 cgtcattgac ataaagcatc acacgtgttt tttgtatcat catttgaccc ttctttctat
    66481 ttgattttct ttcctgtcta taaactgatt ccattatatc acgaaagcgc aaacaccttg
    66541 tgtttgatac tattcaagaa aaataaagca atagtttcta ggattgcttt cctccacaaa
    66601 ctttttttac aaaaaaaaaa cggcaatgaa tgccgctctt cttatttcga ttcttttata
    66661 attctgcttc tgattcatct ttggttagtg tgtgtctaac actagttacg ccaaatgttt
    66721 gatcgatttt ttccttcaac gcttcgattg cctgtgcgcc acgtgccgct tgttcagcat
    66781 tgatggattc aatgaccagc accgctgctt gtgtttcttc cgtcagcatc gttctttggg
    66841 cttcacgcca gttgagacag cgacagatcg ctccttgttc atcatagtag atgatttctt
    66901 ccggaagtgc cggagcatcg gaatctgcac ctaaaggcag gaatgattcg ccaccttggg
    66961 cttttcctaa atgcagattt cctgcgatct tttcgatatc ttctccgccg caaggtacgc
    67021 caaaagacaa ggaaatacta ttatagatat ctacaagcgg attgattggg aaaaattccc
    67081 gttcttgatt tgcacgtttc agtaaagctt caatagaaga acgtgcacct tttttagtct
    67141 tgaatgtggt aaatgcctga cgccactgag caatgacttc gttttggctg aatgtttctt
    67201 ctgtaaggta atttcttgct tcttttgctg cctcattcaa taattgatga tacgtttctt
    67261 cactttcttt tgttacgtgg ttatcgatac catttacgga taagatttcg atggttgctt
    67321 caggaaatac ttcccagaaa ttggtatcca ctattacttt tttcatctgt tcacacctct
    67381 tgattagaat aattgcttga tgaatagata gtctgtttgg ggatcatctc ccatataaaa
    67441 aacatgttcg ctgtatttga taaatccttt tttacgataa aaagcgagcg caacatcgtt
    67501 gtgttcccaa acaccgagcc aaatggctgt tttttgcttt tcttttgctt tttcaatagc
    67561 tgtatctagt aaaaatgtac cgataccttg atgtttaaat ttttttcgta catagattcg
    67621 ctcgatttct aaaaaatgat cagccatttc ctcagattga ctcgttcctg tatttagttt
    67681 caggtaaccc gcaggctctt gatcgatact cactaggaaa aaatcggttt ctttatcttt
    67741 tagctcttct gtaagttttt ctagtgcata agcttgtgtc aagtaatcag ctaaatgctc
    67801 cggtgaatta tcttttccaa atgtatctgt aaatgtttcg atactaattt gttgtagtaa
    67861 gtctacatct gaaggcgtca tttttcgaat ttcgtattta ttcacggctt cttcctttca
    67921 atagatcctt ttattgcctt ttttgacaaa attccaatct tcgctaacat tcttgcatac
    67981 tttatttaaa agatattcca attgttttgc ttcttcgtca gaaagaccat ttaatgcgac
    68041 tgcattggag tagttgtttt ctcgaatgat gaaaggatag atttctgctc cttttttagt
    68101 cggatagagt ttcttgattt ttttattttc tttatcttcc aaacgttcga tcatcccatt
    68161 ggattctaat ttcttgattg ctcgggcagt cgttgtacga tctactttga tcatttctgc
    68221 tagtttttct tggatgattc caggattttc gcaaatacgt actaaataaa gatactgtcc
    68281 tcttgttaaa tcgacttctt tgaattcgat attgctaata gaatctagcg ctcgggcaat
    68341 cattccgatg tctcgaagga tttcagccat ttcatcccac ctttattttg tttgtaagac
    68401 tagttcacct ctttttgttg caaatgcaac tattttcaat aaaaaaatca agttcttttt
    68461 taataactag taaagtatat tcttttcttc ttttacgaaa aagctcaatc acaatagatc
    68521 tggtttttgt tttctaaaat aagtaactgt ttcttcgttg ttcgcttttc tgatagcttt
    68581 ggcaactctt ctatactaaa aaatcccatg ttggaagttt cattattctc aataaacttg
    68641 gcctcttcac cgtggatcgc acaagcaaaa acaagtttat aatactgaaa aagctgtgga
    68701 atatcttttt gtttattcgt atcaaaaact gctcgcaact gagtagtttc tactgttaat
    68761 cctgtttctt catagacttc tttacgcaca ttttcttcag gagacaatcc tatttcagca
    68821 aatccaccag gaagtgacca ttctttcgtc cgtttatctt cgattagtag gaccttgcca
    68881 tcttttttga tataggcacg aacatctact tttggtgttg gatgtccttc tccaatcgtt
    68941 gtgagcgctt ttatttcttc gaaagtttct tttcctattt cactgatcag ttccaatgaa
    69001 atcgtccgga tctcctcaaa acgctcttta tcaaatacat cttttccata atatagacca
    69061 gcttgagaaa gtgcgagtag tcttttgtat tgagccaact tcttgttcat tctcttccct
    69121 tcttttttag caaatgtatg actatgtaat caagtataga agactggttt aattacggca
    69181 aataaatata atgaaatctg caataaataa aagaatgtta aaaaactcga gaacaaaaga
    69241 cattcgactt ctctggggct gtgaataaat ggcgttcaaa agcttgcatc tgcggtaata
    69301 agccccacca aacgaaaaat atgacgagct attcttgtct ggctgttctt attaattgag
    69361 gcaggacagc tttttcacaa cctccccact aaacggtgtt ctcctaccaa ctcctcggtc
    69421 acaagtcaca atattcatca aacatgagaa gctgtttttt tgaaattgct ccttgtgact
    69481 cggagctgaa cgacaggctc acgacctctc ggtaaacagc gttcaaaagc caatttttcg
    69541 atattaagcc atttctttgt tacttattgt cattgatttc tttttctaat ttatccaata
    69601 gtggagtgta atccacttga gtatagtctg ttacatcaaa ttcatatagt gttcctaact
    69661 ggaatttgtc atattttcgg tcggcgatga tctttttgaa tgcttctttc gtaatatgat
    69721 tggtcccttt cgttcgatct tccaatacgt caccatagtg ataatgatcc atgatatagc
    69781 tcaaatgacg atctgattca cgatcacgtt tgtaccgacg ttgccataac acttcaaagt
    69841 ctgctgttag gcgaatcgtg atcacctgat atccgtatct atctgctaat tcttggagtc
    69901 gtgctttttg cttatcacta aaaggatact cggacacaat cactttcttt cctgcttcca
    69961 tatacaaatc aagtgctttg taatagaaag gataaacttt cgtcctttct tgttccgccc
    70021 gttcttccaa attgttaaac ccgatggatt ctgcatagta ttccttgatt tcatcgagcg
    70081 tgatggcata catatctgga aatcgttccc gtagtttatt cataagatat gtttttcctg
    70141 taccaggact accagccaga agaatgaaat actttttcat ctcatttatt tcctaagtta
    70201 attggacttt ccaagttcat aaacagtcca atcttatgct tgacaatttc ttttactgct
    70261 tcatttgctg gaatcacatt atggcgaaga gacttgttga tttctgtttc actaaaggtt
    70321 tctttagcta ctttcgtcca gttgactaaa agctccgttc caacattgaa tttgcggatc
    70381 ccgttattga tcaattcagg ataatcttct tctttcacac ctgttcctcc atggataact
    70441 agggggacat caactactgc atcgatttct ttcagcaagg gaatgtttac ttctgttttt
    70501 gatttgaatt gtccatgatt cgtaccgata gcaatagcta atgcatccac gcctgtagct
    70561 tctacaaatt tcactgcgtc ttccggtctt gtatatacct tgtcattttc agcgacatgg
    70621 attccttctt ctgtaccgcc gattgttcca agttctcctt ctacggaaac accgtgcgca
    70681 tgggcatatt ctactactgc ttttgtcttc aggatatttt ctttgaaagg cagatgggac
    70741 ccatcataca tgacagaagt atatccgctg tcgattgctt ctttgatatc atcaaagtct
    70801 cgggcgtggt ctaagtgcaa gactgcatca accatttctt cttctgcaat agctgtcatt
    70861 acattgacta acacatgcat gccgatatat ttagcggtat cgacacttgt ttgaataatg
    70921 atcggcgaac ccatttcttt tgctgcgcct agcatagcag gaagcatttc taggttatgc
    70981 gtattaaaag ctccaactgt aaaattcaac tcttctgctg tttttgttac ttctttcaat
    71041 gttgtataca tcttttattg ccaccttatc tttttatttg tttcctttga tcgttacttg
    71101 ttttgcaatt tgtcgcatct catccatttt gcccatgtag taatcgatcc cttgatcatc
    71161 accagcacga gcagcatctg cacgcttctg gttatagagg ctcatcagtt ttttataccc
    71221 atctccgatc gtctgtttat tttccaaact cttttctaaa tattggatgg cttgatcgtt
    71281 cacatacaat tcagaaaatt taagtccaac ttgttcataa agtttcgcta atttatgctt
    71341 atcttgggta gtggaaatct cttgtttcaa ttgtgtaatc tctgattgaa tcttttcggt
    71401 cgcttctggc gatagggctt tttcttcttt tgccagaact tttttcggtt ctttttcttt
    71461 tttcttaaaa aatccaaaca tcattttccc tactttcaat taaaatgctt tcaaaactgg
    71521 gcttaagatc caggcatata agagtgctgc ggctactgta tctacatcgg ttgctgtagc
    71581 attgttgaat cccatcgaat taaagatcgt tactagcaaa gcgggcaata atgtaataaa
    71641 gaaaccatga gcaataccgc caatgatcgc tcctcggcgt ccgccaactg cgttgccaaa
    71701 tatccctgct gtccctccgg caaagaaatt ggttagcata ccaggtaaaa tcatcgctaa
    71761 gccgaacatg ggcaaagtaa acatggcaat aatcgtacca atcgttgtcg taatgaaacc
    71821 taaaatgaca gcatttgggc tataaggaaa gaaaactgga caatctaagg cagggatcgc
    71881 atcaggaact aatttcatag ctatccctcg aaatgccggc acgatttcac ctaacagtag
    71941 acgtacacca gctagcaata catacacacc cactacgaat tggatggctt gtaaaaaggc
    72001 aaacatgata tagttttgat ctcctgataa ttcagaagcg aatggttcgc ctgcaaataa
    72061 aacagtgatg atatatagcg ggaccatcac gaccatgaca gacaaataag tatcttgcag
    72121 aaattcgaaa tgtgtcggca acttgatatc ttcgatcgac tttttatttt cgcctttctc
    72181 accaaaaagc ttagcaacac cggcttcaaa taagtacccg atcgtacaaa aatgacctaa
    72241 agcaatatca tttgatccag tgattttacg aatgatcggt tgcgctactg ccggcatagc
    72301 aatggcgaaa caagctccga taaaaccacc gaccaagatc aatacgatcc ctcgcagacc
    72361 ggcaaaatag ccaaagactg tcgtcatcgt tgccatccat aaaattgctt gaccagttaa
    72421 aaaaatgtac ttccattttg tgaaacgagc caaaataata ttgaatacaa aaatggctaa
    72481 gaacgtcagt gcaatatctc tacctaaacc caaatcattc attgcttgac cattgataga
    72541 ttcaatagaa gggatgatcc cttgcatatg aaatccttca gtaaagattt tcccgaaata
    72601 agttaaactt ccaacgatga tgctcgaacc ggcactcaac acttgaaatc ctaggagtgt
    72661 ctttaacgtg ccagagatga cttgtcctgc tgatttcttc tgcagtagta gacccaacat
    72721 agcaatcaat gcaatggtga tcgatgcctg agtcaaaata ttttcgatga taaaattgat
    72781 aacgcccat
//
LOCUS       DBBGSP010000006        72581 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000006 DBBGSP010000000
VERSION     DBBGSP010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 72581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.006"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..1087
                     /locus_tag="ACIZE9_000477"
     CDS             <1..1087
                     /locus_tag="ACIZE9_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6092370.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="ACIZE9_000478"
     CDS             complement(1305..2447)
                     /locus_tag="ACIZE9_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6092371.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="ACIZE9_000479"
     CDS             complement(2452..2637)
                     /locus_tag="ACIZE9_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HGC6092372.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2991..3236)
                     /locus_tag="ACIZE9_000480"
     CDS             complement(2991..3236)
                     /locus_tag="ACIZE9_000480"
                     /inference="COORDINATES: protein motif:HMM:NF024059.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092373.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3230..3631)
                     /locus_tag="ACIZE9_000481"
     CDS             complement(3230..3631)
                     /locus_tag="ACIZE9_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGC6092374.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="ACIZE9_000482"
     CDS             complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="ACIZE9_000482"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HGC6092375.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5649..7415)
                     /locus_tag="ACIZE9_000483"
     CDS             complement(5649..7415)
                     /locus_tag="ACIZE9_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="HGC6092376.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7428..8222)
                     /locus_tag="ACIZE9_000484"
     CDS             complement(7428..8222)
                     /locus_tag="ACIZE9_000484"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6092377.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8232..9608)
                     /locus_tag="ACIZE9_000485"
     CDS             complement(8232..9608)
                     /locus_tag="ACIZE9_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6092378.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(9728..10375)
                     /locus_tag="ACIZE9_000486"
     CDS             complement(9728..10375)
                     /locus_tag="ACIZE9_000486"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HGC6092379.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="ACIZE9_000487"
     CDS             complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="ACIZE9_000487"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HGC6092380.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="ACIZE9_000488"
     CDS             complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="ACIZE9_000488"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HGC6092381.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13042..14673)
                     /locus_tag="ACIZE9_000489"
     CDS             complement(13042..14673)
                     /locus_tag="ACIZE9_000489"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HGC6092382.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            14977..15648
                     /locus_tag="ACIZE9_000490"
     CDS             14977..15648
                     /locus_tag="ACIZE9_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6092383.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(15808..15999)
                     /locus_tag="ACIZE9_000491"
                     /pseudo
     CDS             complement(15808..15999)
                     /locus_tag="ACIZE9_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            complement(16367..16708)
                     /locus_tag="ACIZE9_000492"
     CDS             complement(16367..16708)
                     /locus_tag="ACIZE9_000492"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092384.1"
                     /translation="MSIDDCLEEQIRLFLKFLKVKVQNNYFTCYSYAHPVLNSLPFNS
                     LVQGLITNIVLLVCTPNEIFVKKIGSGISSVRLKEKEYTQKIIHIPKPEIKRFEIKDY
                     SALGLFSIGYW"
     gene            complement(16805..17257)
                     /locus_tag="ACIZE9_000493"
     CDS             complement(16805..17257)
                     /locus_tag="ACIZE9_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092385.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(17264..17812)
                     /locus_tag="ACIZE9_000494"
     CDS             complement(17264..17812)
                     /locus_tag="ACIZE9_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HGC6092386.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(17857..18189)
                     /locus_tag="ACIZE9_000495"
     CDS             complement(17857..18189)
                     /locus_tag="ACIZE9_000495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092387.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(18203..18460)
                     /locus_tag="ACIZE9_000496"
     CDS             complement(18203..18460)
                     /locus_tag="ACIZE9_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092388.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(18655..19197)
                     /locus_tag="ACIZE9_000497"
     CDS             complement(18655..19197)
                     /locus_tag="ACIZE9_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HGC6092389.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VGQEAQKIDAIKIYYVRSAY"
     gene            complement(19218..20309)
                     /locus_tag="ACIZE9_000498"
     CDS             complement(19218..20309)
                     /locus_tag="ACIZE9_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC6092390.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(20317..22527)
                     /locus_tag="ACIZE9_000499"
     CDS             complement(20317..22527)
                     /locus_tag="ACIZE9_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HGC6092391.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(22543..25071)
                     /locus_tag="ACIZE9_000500"
     CDS             complement(22543..25071)
                     /locus_tag="ACIZE9_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6092392.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(25123..25533)
                     /locus_tag="ACIZE9_000501"
     CDS             complement(25123..25533)
                     /locus_tag="ACIZE9_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HGC6092393.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(25546..25764)
                     /locus_tag="ACIZE9_000502"
     CDS             complement(25546..25764)
                     /locus_tag="ACIZE9_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpD family membrane protein"
                     /protein_id="HGC6092394.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(25761..26753)
                     /locus_tag="ACIZE9_000503"
     CDS             complement(25761..26753)
                     /locus_tag="ACIZE9_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGC6092395.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(26832..27743)
                     /locus_tag="ACIZE9_000504"
     CDS             complement(26832..27743)
                     /locus_tag="ACIZE9_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGC6092396.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(27762..28106)
                     /locus_tag="ACIZE9_000505"
     CDS             complement(27762..28106)
                     /locus_tag="ACIZE9_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092397.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(28126..28404)
                     /locus_tag="ACIZE9_000506"
     CDS             complement(28126..28404)
                     /locus_tag="ACIZE9_000506"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092398.1"
                     /translation="MSVEHFCDCYIALLRSQQLLTVERYGAEFGYVLQAERHRATRCY
                     EKEDQVIDGYEELCIRNNRYLQQRLYEQLMMDFSNLYRGYECSMIQER"
     gene            complement(28763..29263)
                     /locus_tag="ACIZE9_000507"
     CDS             complement(28763..29263)
                     /locus_tag="ACIZE9_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092399.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(29264..29809)
                     /locus_tag="ACIZE9_000508"
     CDS             complement(29264..29809)
                     /locus_tag="ACIZE9_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092400.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(29806..31062)
                     /locus_tag="ACIZE9_000509"
     CDS             complement(29806..31062)
                     /locus_tag="ACIZE9_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC6092401.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(31422..31733)
                     /locus_tag="ACIZE9_000510"
     CDS             complement(31422..31733)
                     /locus_tag="ACIZE9_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092402.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(31756..33231)
                     /locus_tag="ACIZE9_000511"
     CDS             complement(31756..33231)
                     /locus_tag="ACIZE9_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HGC6092403.1"
                     /translation="MKAHFFKYRGRRIRYFNRYLWFCYYGFFLFPFLILLGWFSWKVF
                     YPRLSTFSNWQMYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLVRML
                     IDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGHLLS
                     EVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPNMLI
                     AGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEEMII
                     CLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDMEARN
                     RVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYLMTF
                     GEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYDFTV
                     KEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(33680..34132)
                     /locus_tag="ACIZE9_000512"
     CDS             complement(33680..34132)
                     /locus_tag="ACIZE9_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092404.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(34134..34499)
                     /locus_tag="ACIZE9_000513"
     CDS             complement(34134..34499)
                     /locus_tag="ACIZE9_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092405.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(34598..38881)
                     /locus_tag="ACIZE9_000514"
     CDS             complement(34598..38881)
                     /locus_tag="ACIZE9_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HGC6092406.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(39028..39267)
                     /locus_tag="ACIZE9_000515"
     CDS             complement(39028..39267)
                     /locus_tag="ACIZE9_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092407.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(39357..39599)
                     /locus_tag="ACIZE9_000516"
                     /pseudo
     CDS             complement(39357..39599)
                     /locus_tag="ACIZE9_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(39712..39948)
                     /locus_tag="ACIZE9_000517"
     CDS             complement(39712..39948)
                     /locus_tag="ACIZE9_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092408.1"
                     /translation="MFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTELKDKN
                     NVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(40959..41870)
                     /locus_tag="ACIZE9_000518"
     CDS             complement(40959..41870)
                     /locus_tag="ACIZE9_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092409.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(42066..43901)
                     /gene="lepA"
                     /locus_tag="ACIZE9_000519"
     CDS             complement(42066..43901)
                     /gene="lepA"
                     /locus_tag="ACIZE9_000519"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGC6092410.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            44048..45268
                     /locus_tag="ACIZE9_000520"
     CDS             44048..45268
                     /locus_tag="ACIZE9_000520"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6092411.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            45288..45782
                     /locus_tag="ACIZE9_000521"
     CDS             45288..45782
                     /locus_tag="ACIZE9_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HGC6092412.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            45760..46446
                     /locus_tag="ACIZE9_000522"
     CDS             45760..46446
                     /locus_tag="ACIZE9_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092413.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(46597..49206)
                     /gene="clpB"
                     /locus_tag="ACIZE9_000523"
     CDS             complement(46597..49206)
                     /gene="clpB"
                     /locus_tag="ACIZE9_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HGC6092414.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(49457..50503)
                     /locus_tag="ACIZE9_000524"
     CDS             complement(49457..50503)
                     /locus_tag="ACIZE9_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HGC6092415.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(50514..50786)
                     /locus_tag="ACIZE9_000525"
     CDS             complement(50514..50786)
                     /locus_tag="ACIZE9_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGC6092416.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(50821..51729)
                     /locus_tag="ACIZE9_000526"
     CDS             complement(50821..51729)
                     /locus_tag="ACIZE9_000526"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGC6092417.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(51861..53093)
                     /gene="pepT"
                     /locus_tag="ACIZE9_000527"
     CDS             complement(51861..53093)
                     /gene="pepT"
                     /locus_tag="ACIZE9_000527"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGC6092418.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(53108..54229)
                     /locus_tag="ACIZE9_000528"
     CDS             complement(53108..54229)
                     /locus_tag="ACIZE9_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGC6092419.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(54226..54927)
                     /locus_tag="ACIZE9_000529"
     CDS             complement(54226..54927)
                     /locus_tag="ACIZE9_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGC6092420.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            complement(55071..55511)
                     /locus_tag="ACIZE9_000530"
     CDS             complement(55071..55511)
                     /locus_tag="ACIZE9_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HGC6092421.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            complement(55640..56566)
                     /gene="dnaI"
                     /locus_tag="ACIZE9_000531"
     CDS             complement(55640..56566)
                     /gene="dnaI"
                     /locus_tag="ACIZE9_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGC6092422.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            complement(56566..57939)
                     /locus_tag="ACIZE9_000532"
     CDS             complement(56566..57939)
                     /locus_tag="ACIZE9_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HGC6092423.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELKKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            complement(57962..58453)
                     /gene="nrdR"
                     /locus_tag="ACIZE9_000533"
     CDS             complement(57962..58453)
                     /gene="nrdR"
                     /locus_tag="ACIZE9_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGC6092424.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            complement(58765..59097)
                     /locus_tag="ACIZE9_000534"
     CDS             complement(58765..59097)
                     /locus_tag="ACIZE9_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGC6092425.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            complement(59149..59778)
                     /gene="coaE"
                     /locus_tag="ACIZE9_000535"
     CDS             complement(59149..59778)
                     /gene="coaE"
                     /locus_tag="ACIZE9_000535"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGC6092426.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            complement(59742..60578)
                     /gene="mutM"
                     /locus_tag="ACIZE9_000536"
     CDS             complement(59742..60578)
                     /gene="mutM"
                     /locus_tag="ACIZE9_000536"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGC6092427.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKVLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            complement(60623..63268)
                     /gene="polA"
                     /locus_tag="ACIZE9_000537"
     CDS             complement(60623..63268)
                     /gene="polA"
                     /locus_tag="ACIZE9_000537"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGC6092428.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            complement(63394..64077)
                     /locus_tag="ACIZE9_000538"
     CDS             complement(63394..64077)
                     /locus_tag="ACIZE9_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HGC6092429.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            complement(64070..64555)
                     /locus_tag="ACIZE9_000539"
     CDS             complement(64070..64555)
                     /locus_tag="ACIZE9_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HGC6092430.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            complement(64862..66196)
                     /gene="murC"
                     /locus_tag="ACIZE9_000540"
     CDS             complement(64862..66196)
                     /gene="murC"
                     /locus_tag="ACIZE9_000540"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGC6092431.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            complement(66327..67088)
                     /locus_tag="ACIZE9_000541"
     CDS             complement(66327..67088)
                     /locus_tag="ACIZE9_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HGC6092432.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            complement(67104..67586)
                     /locus_tag="ACIZE9_000542"
     CDS             complement(67104..67586)
                     /locus_tag="ACIZE9_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGC6092433.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            complement(67606..69786)
                     /locus_tag="ACIZE9_000543"
     CDS             complement(67606..69786)
                     /locus_tag="ACIZE9_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGC6092434.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            complement(69930..70661)
                     /locus_tag="ACIZE9_000544"
     CDS             complement(69930..70661)
                     /locus_tag="ACIZE9_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC6092435.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            complement(70730..71671)
                     /locus_tag="ACIZE9_000545"
     CDS             complement(70730..71671)
                     /locus_tag="ACIZE9_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGC6092436.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            complement(71851..72219)
                     /locus_tag="ACIZE9_000546"
     CDS             complement(71851..72219)
                     /locus_tag="ACIZE9_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HGC6092437.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
BASE COUNT        21241 a        15234 c        11304 g        24802 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta atttctagct gacttatcat atattcatct
     3061 acataggtaa cgaattgacc tacctcgtta aatccatttg tcaaacataa cttagccata
     3121 taagaatgat aatgtttgag tatcatcttg atcgaaattg gatctccttc tagagcagat
     3181 aagataatgg atagtggaac taataggtac tgccgctttt tagatttatc taccataggt
     3241 cataccccat tttcaattgt tcaactgcct tctttcgttg ataccagata ccacttgtgc
     3301 tcatattgag aattttaccg atttcagcat cattaaaacc tgcaaaataa taaagtagga
     3361 taatctttct tcttatctcc gataactgat caattgctgc tgataacttt tgatctgaaa
     3421 ttaatatttc cattccaaat aagaaataga catcttgttc atcaaaatga gtttgggaat
     3481 acctgccttc atttgaatct gccaatggtt cctcattatc ctttatgtta gcgtttcgtt
     3541 ttcgaataga cttagcttcg tttcgtaata cttttttaca gtaggcatca aattggtgtt
     3601 gtatagatat gtcattgtaa tgttgttgca tgataatatg ctcctttttc cccctttcca
     3661 ctaatacaac aatcagaaag cccctttttt tcgaaaaaac tagaaaaaaa acataaaaat
     3721 atttatcatt ctttaaacag aaaatctttc tataaaaaac aaaaaaaaac gattaggcta
     3781 ggctaatcgt tttttgaaca ttcttaaaaa atccaaatta ttttttataa ctgaaattgg
     3841 gtattgatga ccatcgtttc tgtagatagt aagcaatcat tttaggtttt ctatctctag
     3901 taaagattcc tttcttattt ccttgcactc ttaaaatccc ttgacttgtt gcaaaatctg
     3961 caaaattcca cacttgttca ccaacaaaat tttcacatgt atctattact tcgtgatttg
     4021 cttcgtaata agccacttga tactcttctg taaacattgt tggtactgta tcatgaaatc
     4081 cagctactgt atctgctcca tattctgtaa acattattgg cgtatcagga catctttcca
     4141 tccatccatc tagctctttt ttcaacagat attttgcatg tgccagatcc cctcccgaaa
     4201 cataccaacc ataataacga tttaaacata aaacatcgac aatatctcct accttacaaa
     4261 catctggcgt tgattttaga taagtaacga ttgttacagg tcttttctgc ggatcaagtt
     4321 ctttagttaa ttcaactaaa ggttcaaaat attctttagc accttcggaa tccgaatctg
     4381 gttcatttgc aatagaccac attacaacac ttgggtggtt cttgtcgcgt tctatcaatt
     4441 ccttgatcac cgttttatga gaattttctg ttcgtatctc tttccacgta ttatgttttt
     4501 ccacattatc atctaataaa gtggccatga aatttaaatg taaccctact gcaggtactt
     4561 catcaataac tacaatacct tctcgatctg ctaatcgcat aatttcttct gagtaaggat
     4621 aatgtgatgt tctaaaagaa ttagcaccta tccatttcat taaattaaaa tctttaatat
     4681 ttacagcctc attcaaacca cgtccattaa catacgaatc ctcatgctta ccaaatcctt
     4741 taaaataaaa aggtttatta ttaatcaaaa atttgccatt ggtaacctga acactgcgaa
     4801 taccaaattc ttctgtatag gtatcgatca ctttattatc atcaattaaa ctaattttca
     4861 tactatataa ataagcgtct agaggttccc aaaaaattgg attcttaagc tgaatcattc
     4921 ctttctttcc ttcagcttca gctacaagtt gagcctcttc gtcatatatc gctattaaga
     4981 tttttccggt ccattctgta tcgatattga attctacact tgcatccaaa tcagttattc
     5041 ttgtattaat agtaatatca cttatatagt ctttcggagt tgtatataac ttaacaggtc
     5101 tatgaatacc tgcataattg aagaaatcaa aattaactaa gttttccttt tttatatccc
     5161 cattttcctg tactgtttcc ttcataatcc ccacaggtaa agtactatcg tcaataatat
     5221 tgtttacagc aactgtaatt cgattattcc cgtcttttac aaaccgatta atttcagact
     5281 caaatggtgt aaacccacct ttgtgttgag taataaactt tccattcaaa aaaacttttg
     5341 cttcatgtgt tgcagatcca aaacgaagaa ctaatctttc ttctaataat cttttaggaa
     5401 gagtcacttc tttttcatac cacacccatc caacatgatt tctaatgttc tctgtttcaa
     5461 ataaatcatt ataagaagag ggaactgaaa tcggataact ctctttttca tttattggtt
     5521 ctaaagcaag ttcttcctgt aagtcatcat ttgtatctaa tttaaatctc cagagaccgc
     5581 ttaagtcaat tacttgcctc gtctctgtca taatgggata caacatataa accactccta
     5641 tctaaatatt aaataaatgt atcctttaaa ccacaataag catctattgg acttactccc
     5701 ttaaattcag aaagacccat tagtttgtcc accaatattt ctaaagtttc ttgttttcca
     5761 tcataagtat taatataagt ctttacttga ggtacatcag ccaaatgaaa cggacactgt
     5821 acagatacaa aaattgttgg aatttcatga atgtaaaacg gtatatccgg agttccttta
     5881 cttgctggcc agacaattcg ttgaactgtg cctggattaa cattagctat attaatgatc
     5941 aagtcatatt ttttagttaa atttttaatt ggtctcttag cagcatatat tccagctata
     6001 tttttaattt tttcttcttg cgataatcct ttcaattctt cttcaggtga aatgtatttt
     6061 tcaacttcaa atccttttgc tgacaaaatc tgtttcaata aatcaatggc ttgaggtcta
     6121 tttccagcaa ctacttcacc aaacccacct tttaccccat gtacatctac tagtaaaatc
     6181 cttttatatt tttctggtac aataggccaa atatcttgtt tatctttaac taatgtaatt
     6241 gcttggtcag ccacctcttt aaaaattgat ttattttcaa ttaaaccaat tttttccaga
     6301 gcttcttgct taggtaataa aatttgttct tttgcttttt tgtgtaatcc caatttagct
     6361 tttaacccta aaattctttt taaggcatct aataaccgat catcagtgat aattccttta
     6421 cgatagcctt ccatcatata attaaagtct tcatctggat cattaaaaaa tagaaataga
     6481 tcacatccag ctgcaataga agtgggcaat aattctgatc gtttcattgc cccagtcatt
     6541 cctaacatat gactagcatc agtaactact aatccattaa atccgagttt tcctctaagt
     6601 aagtcagtga ttaattcttt tgataaagtt gcaggaagta aatcttcatc tttcagatca
     6661 ggattaaaat gttttgaata agctggcata tggatatgac ctgccataat tgaaggtaat
     6721 ccagcttcta ttaagcctga gtatactttt ccaaaagaat tatcccattc ttccgtacct
     6781 aaactattaa tactaaaaga tagatgctga tctcgttcgt caataccgtc accagggaaa
     6841 tgtttagctg caggcaaaat tccactctcc tgaatacctt tcatataagc taaactaagt
     6901 tctaaaactt tatcagggtt ttgtccaaaa gatcgactag aaatgatagg atttctccaa
     6961 tttctattaa tatctacaat aggagcaaaa ctccagttac atccaatagc cgatgcttca
     7021 atcccagaaa ctctccctaa ttcataagca tatttcgcat catttgttgc accaattttt
     7081 acttctacac caacttcagt accatctgta caagctccgt taccacctgc ttccgtatta
     7141 gcagcaatta atagaggaat tttactttct gtttgtaaga tatagttttg atcatatacc
     7201 tcatcagcag ttcctggatt atatcgtaca gctccaatat ggtactgatt gaccatatta
     7261 ctcaagtaat ttttatcacg actagatccc atattaacaa acaattgacc tattttttct
     7321 tccaaagtca tagaatcaat cgtctcttca atccaagaaa tagcatcttc atctaaatta
     7381 tatggttttt ttcgtaaatc tacttttata gtcattttct ttctcctcta cttattagta
     7441 agatttttcc aaaaagtatc tatatatttt tgttcaatat ctacataatc tcccgataaa
     7501 catttaaata aaacatcagt tcttaagttt tcccatgatt ctttttcttt attgaccaaa
     7561 ataggataaa agaaaacttt atttttattt gcagcttcta gatcaccagg agaatcacca
     7621 atcattaata tcttatccaa atcacaacca ttttcaatta cacttcgaat aatatcttct
     7681 ttttttcctt tatcttgaca acacagttca tcaactaatg ataataattc atgtctttcc
     7741 cattcttctt gaacagcttc cttattagct gagcttacaa taattatctt cccatatttt
     7801 ttcagagctt ttatagtatc tctagcactt aaaaagggtt tatctaatcc ttttgcttga
     7861 ctaatctgtt gattgacttc ttccgaccat tttaaagctt ttaataaatc ctctgactga
     7921 gaatattcta tttccctctt caaagatgga ttagacaatt cttttgttag agatacccag
     7981 tgctttaatc gattaatcga tgttacatca tttttttcta atgttttaac taaacctaaa
     8041 aatctgttta ttccacgagt ctctgaatat aaattaatat tattccaatc ctgtaggaat
     8101 ttttctctat gatgaacatc aaaaatctct gcagcaattg gtccgaaaaa gagattgtgt
     8161 ttataagtca tcgtatccat aacacagcca tctgaatcaa tacaaaatat ccaattattc
     8221 atatttctct cctatttatg tttttgtttt aaaagctcgc aattttctaa gactttatct
     8281 ttagataatg gataaaggaa aaataaaatt aatcctacaa tcagaaaaca aattgatgga
     8341 attaatgttg aagcgttata taacttttct aaaacatctc ccgtttgtac atttgctaaa
     8401 gagtcatagc ctataataga aagagtccaa cctccgacgc ctccagctag agcttgacct
     8461 atttttctag caaaagaata taccgcatat acggtcccat cttctctttg atcagacttt
     8521 acttcttgat catcaataac atcagtaata tttgcccaaa taacagtatt aaacacaccc
     8581 aaacccatat agccaaccga actaagaatt aagaatacat acatattact agcttttatc
     8641 aaaaataaga tcaaatatac tattgctgaa aagaacattc ctactgatgc cagttctttt
     8701 tttccatatt ttttacttaa aaacaaagtt aaaggcgaaa caactattaa aaccaaaata
     8761 ggattgataa aattcattaa aactattccc tgtgcatcat tatagtaatc aggaaataca
     8821 taattattca tactcataat taataattga gcaaggagta agaaaatagc cgcaccaatt
     8881 atagaaagta atgccctatt tttaactaac ccttttaaag attttaacaa tgaaactttg
     8941 tattgagatt ggtcaattct tactcgttca gtagttagtt tataacatat taaataacaa
     9001 ataagtgcac atatcgaaaa tattcccgca acaattgtaa aagttgatcc accacgaact
     9061 atttgagcgc ctgaatcatc tcttgtataa ataaataatg gtgttaatac accaatgacc
     9121 aaacttgcta aagtagctcc aacatttcgg aatgtcgata gcattgttct ttcttctgta
     9181 atagaagtaa tagctgatgc cattgatcca taaggaatat ttatagatgt gtaaaaaata
     9241 ctcccccata atatatacgt aacatacatg tatactacct taacgctcat agaagctgaa
     9301 atcatagaag tttgatacat taaaaaactt gctaaagcga ctggaccact cattcttaaa
     9361 atccacggtt taaacttacc ctgcttagtt gctttcgatc tatcaacaat acgccccata
     9421 gttacatcag taactgcatc gataaatctt gctactaaaa ataatgttcc aacggcagct
     9481 ccgcttatcc ccaatacttt tgtataaaag atcattaaaa aagaactagc aaaaatgaaa
     9541 gtaaaatcgt ttccaaaatc tccaaacata tatcctattt tgtctcttat accaaatttt
     9601 ctttccatac aattctctcc cttctgttgt taagcgtttt cattctgatg aaagtacgta
     9661 ctatactctg aagcgtaaag agtcagtatt tattttttac atttcagagt attatttgtt
     9721 ttttctccta ataattcttt atctcataaa acttatctat atatttacta gctactcgac
     9781 ttacttcttc aaaatcacct ttttcaacag aagccaataa attcccacct acaccaactg
     9841 caacaactcc tacttcaaac caatcttcta agttctctat acttactccg ccagtaggca
     9901 ttatatttac gtgtggtaat ggagcttgat aggcttttac aatggatgga ccaaaagcag
     9961 aacctgggaa tagtttaatg atatctacgc cagcagtaag tgcctccttt atctcagtaa
    10021 ttgtcataca acctggtaaa taaggaattt gatataaatt acaaatctca gctgtttgtc
    10081 gatcaaaaga tggactaacg atatattctg ccccagccat aattgcgata cgagcagtaa
    10141 acgcatctaa aaccgtaccg gctccgatta ttacatcttt ttgatcagca tattttttag
    10201 caatttcttt gattatttct tcagcattag gaactgtaaa agttagttca atccctttaa
    10261 ttccacccgc aataattgaa tttattgctt taatggcctc atccttattt ttcccacgta
    10321 caaccgcaat gactccagcc gcttctaact tacttaaaat ttctactttt ttcatatcta
    10381 tctccttcct ttatggatac atactttgtc tagctgtact aacttacaaa gaataaattt
    10441 aagcttttat ttcaagtatt attttctact tccgatttca aaaaaattaa aataattata
    10501 cgcattacga taacaaatat tctccactat ctgactaaga tacatttcat catctggaat
    10561 tcggcctgct ttaacccact cgcttagtaa ttgacataat actcgacgaa aatactcatg
    10621 gcgaggatag cttagaaaac ttcgagaatc agtcaacata cctgtaaaat tcgacaacaa
    10681 actttgttgt gccatcgtag tcaactgttg acgcattcct tcagctgtat cattgaacca
    10741 ccaagcacat cccaattgga ttttttgaat cataccccct tggaagcttt gcattgctgt
    10801 tgctagtgga agccaatcag ttggatttaa tgaatataaa attgtttttg gtaagcaccc
    10861 actcttttca gcggtatcga acaatgctac aacattttgt gtcaaactag cttgatcccc
    10921 catcgaatca ccaccgacat ctactccaat ttgttccttt aatatacttg aattatttct
    10981 taaagcattt aaatgcattt gcatcgtcca accatatctt gtatactcag acatcaaatg
    11041 taattgaata cctgtaacaa attgtgcaat ttctgataaa tggaaatccg tttttcctgc
    11101 taaagctttt attaacagat tgtcgagtat tttttcatct gctatttcat aaaaataagt
    11161 attcaaaccg tgatctgcta atcgacagcc aatttgatga aaatgatcca ctcgttggct
    11221 caatgcttgc ttcaacccat taaagtcttt gattggtata gccgctgttt gactaagttt
    11281 taaaatatag ttcgaaaagc ctgatgattt gatactccag accttatctg gacggaaagt
    11341 aggtaatacc ttgaaagaat tatcctgttt agaaagctca gtatgatacc acaagtcatc
    11401 tgtaggatca tccgttgtac agatggcttt cacatccatc atctccaaca attctttcgg
    11461 gcgataggaa tccgtttgaa ttttttcgtt agcacgtcgc caaatttctg gtgcattctt
    11521 ctcagaaatt gtcaaatcaa tatcaaagta acgttgtaat tccaaatgag accattcaaa
    11581 aataggatta cctggcgcct tctccactgt ttttacaaaa gctaaaaatt tttcataatc
    11641 atcacctgga ccactgatca actcttcttc tataccatta gctcgcatca atcgccattt
    11701 ataatgatct ccagctcctt tatcatttaa ccatacctga gtcaaattct tgtattgctt
    11761 attttctagc aaatatgctg ggtctaaatg acaatgatag tcgataattg gttggtgttt
    11821 tgcaaattta tgaaaaagtc ttttagctat ttcattctct aataaaaagt tcttatctaa
    11881 aaacatattt aaacactcct ttccttccgt tagtttttag aagagaaaat ttttcctcta
    11941 aataaactcc cttatataat tatttactcg cccccttttc aagcgcttcc caaataccat
    12001 ttaaataaac tgcacctaga gctcggtcat ataatccata accaggtcta ccggtttctc
    12061 cccaaatcat ccgaccatga tctggacgaa tatagccatt aaatccatta tcgtacattg
    12121 tttttaatat cttatacata tctagagaac catattctga tttatgcggc gcttcgtaaa
    12181 aatcgagtcc attgtcactt aaatatttga tattacgaac atgtgcaaaa ggaatccgat
    12241 cccgttgaca aaattcagat agaatttcat agacatcatt atctggtcgt tctgcaatac
    12301 ttccagtaca taatgtaata ccattagaag gagaatccac tacattacac aaccaatcta
    12361 aatcgtcacg atttttaaca atacgaggta atccgaaaat ggaatatggt ggatcatctg
    12421 ggtgaactgc cattttaatc ccaacttctt cacatgtcgg gataattgct ttgagaaaat
    12481 atgcaaagtt ctctcgtaat ttctcttcat caacttcttt ataggcttct aataattgct
    12541 taatttgtga taaccgatga ggttcccaac ccggcaattc aaaattatta gtagaatttt
    12601 ctacttctct aataatttcc tccggatcag tagggatatt ttttgaaata taggctaacg
    12661 tagaagaccc atcatctaaa cgataatcca aatccgattt tacccaatca aatactggca
    12721 taaaattata acagataacc tcaatcccaa attctgccaa attgcgaatc gtctgtttat
    12781 aattctcaat gtattgatct cgtgttggta aaccaatttt gatatcatca tgaacattaa
    12841 cactctcaat aactttcaag gtaagtccat tggcttcgac ttcatctttt aaagatttaa
    12901 ttcgttctct cggccaaacc tctccggctg gtatatccat taatgttcca acaattcctt
    12961 tcattgctgg gatctgacga atttcttgta gtgagatttt ttcttcattt gccccatacc
    13021 atctaaaagt catttccata gttactttcc tccaacttct gttatatatt tattgattgt
    13081 tttacgaact gcttgaggac ctactagcat ttcgcaaaag attttttcag ttttctttcc
    13141 taccccaact tgatataaat ctaaaccaaa gatttcttta ttttctaaaa tttcctgtac
    13201 cgcacaatga atctttgaag gatcttgttc acctaatttc aatactgata atttatcctg
    13261 caactctacc aataacggat caggacttgg cacaaaattt tccccttgat catcgactgc
    13321 cagtaaataa cgtaaccaag cagcaatagc gataggaata aatgttagat tttctgcatt
    13381 tccgtctttt tcgacatact ttttaattgt ttcaccatag cgaatcgcta ctttttgaga
    13441 agtatctgtt gcaattcgtt gtggtgtatc tggaatatag ggattaggca aacgtttatt
    13501 aattacttca tcaataaatt gttttggatc aataatgcct ggattttcaa ctactggtaa
    13561 accttctaaa taacctattc ctttgattaa accaaccaaa tcatcatctt gcatctctgc
    13621 tgaaattgat tgatatccta gcagacaacc tgttactgcc aaagcagtat gaagtggatt
    13681 caagcttgtc gtaaccttca tgatgtctgc tttatcaacc gtctctctat ctgtcataat
    13741 cacaccagcc ttttccaatt taggccggcc atttggaaaa ctatcttcaa taactaaata
    13801 atgaactacc tcagtattag tgaaagcagc aatattggta tgtttttttg tgtgaatgat
    13861 atctaaatcc tcgagcccca tcatcaatag atcttccttt acattctctg aaggatttgg
    13921 cgtaattcga tcaatcatac tccaaggaaa agtcactttt tctttatcct ttaaataagc
    13981 aataaatttt tcagaaacat atccttcttt ttgccaagct tctgcaatcg taaaaatact
    14041 atcttgaaaa cgttgaccat tctgtgagaa attatcagta gaaaccatcg caatcggcaa
    14101 ctctccagca ttaaatctgc tatataacaa ggatgttaca atactcatcg tatgttgagg
    14161 attgctaggt ccagatttga tatcagcttt gactaccgaa aagaattgcc ctttagaatc
    14221 ttttaaactg taaccttttt cagtaatagt aaacgttgta aactgtaatt taggatcttc
    14281 aaaatattta accactcttt gatagtccgc tatattcttc ggattgcaat ataaactatc
    14341 agccgttact gccaaaagtc tttttttgag ttcaccatct ccactcataa caatttccaa
    14401 aatgtcattg ttatagtcat gataagcttt ttccactact tcttcatcaa atgtttcaca
    14461 cacaactact cctgtttcta attcattttg atctgctaag cattgagcaa tttctgcatg
    14521 aaatcctcga taaagatttc ctccaccaaa atgaagccat actggatgtt gctggccttc
    14581 ttgcttaact tctttgacat caaaacacgg cagtagaatc tgcatttcat tgaattcttc
    14641 gatagaattt tgccaatttt taatcgaaac cataattaac ctcctcaaac tgatatgtta
    14701 gttttgatac attttatatt ttaaaaccca ttgtaaccgt tgtcaatata aaaagggaat
    14761 aaacttgctt ttttctacca tatcagaatg attgtatttt ttattcagaa aaataaaata
    14821 ctccttcttt ttggactgat tttatcgaaa cttatttttt ctttttttca tgtattcttt
    14881 tatttttata actagtgtat tacttcaaaa tttgatatta tatggcatga acagaattaa
    14941 aatatcagtt aaaataaaag ttaaggagca ttgtgtatga caattaaaac tagtctccaa
    15001 aatcaagctt accaatctat tcgccgacaa attatctatg ctgacttaga acctggaaaa
    15061 aaagtatcag aaaaaaaatt agaagaaaca ctttctattg gtcgtacacc aatacgtgaa
    15121 gcactgattc aactccgaca acaaggtctt gttgatacaa ttcctcaaag cggaaattat
    15181 atctcattaa ttgatttaga ttcggccaaa aatgctcgat ttgtcagaga acatttggaa
    15241 cgacaaatta tgttagagtg ttgtgccaaa atgaataacc aaaaaaaacg gattttagaa
    15301 actataattt cagaacaaga aaaagctgtt agtcaaaaaa atgctcgtag tttttttcat
    15361 aatgataatt tattccataa agcttgtttt gaaattgcag agcgagaaga agtatggcaa
    15421 tggttagaaa ataacaatac acacttagaa cgatttcgat ggctacgagt aaaaacggaa
    15481 ggattaaagt gggaaaaaat tatggaacaa cattatcaac tatttgaggc attaacaaaa
    15541 caagatccag aagaagctaa ctttctaaca tcgttgcatc ttcatttaat gcttaatgag
    15601 caaaatattg ttttagctac tcatccaaaa tatttcaaaa atatataact tttaactctt
    15661 tttaaattaa atggttgttc tgatcagaaa aatatcgctt gttttcttat tatgtaatat
    15721 atttcataaa ctattctgca taacaactat tgtttgtact ttttacattg gataactaat
    15781 tatgactgct gataactttt gatattaaac tagtatctcc aatacaaata aaaaatagat
    15841 atcttgttca tcaaaattag ttcgtggata cttaccttca tttacatcat tcagcggttt
    15901 cccattttct tttattctat tatttcattt tctaatagac ttggcttcat ttcgcaatac
    15961 tttttttcaa taggcatcaa attggtgttg tttagatatt tagttgtagt tttgtgacat
    16021 gataagtatg ctcctttttc tcttttccac taatacaacg atcaaagggt gcttttttca
    16081 aaaaactaga aaaatcaaaa taagattcgt attttgattc tatatatcct gtttcaacta
    16141 catcttatat ttcacaatag aataaatagc cttttgcata gctgcttaac ttataagaaa
    16201 ttgcaattta cttcttcaaa gtgaaaacga atatgagtaa aataaaatta ttcttcttac
    16261 agataattaa aaatagcgcg taacaaaaat cggcattcaa tcacataatt aggattgatg
    16321 ccgattactt atattctacg tatagtttta gtattcttat tttttatcac cagtaaccaa
    16381 ttgagaacag ccctaaagca gaatagtctt ttatctcaaa acgcttaatt tcaggcttag
    16441 gaatatgaat aatcttttga gtatattctt tctcttttaa tcttactgaa gaaataccac
    16501 tgcctatctt ttttacaaat atttcatttg gtgtacagac taataaaaca atatttgtaa
    16561 tcaatccttg cactaaagaa ttaaaaggaa gactatttaa aacagggtgt gcataactat
    16621 aacatgtgaa gtagttattt tgaactttaa cttttaaaaa ctttaaaaat aatcttattt
    16681 gttcttctaa acaatcatct atactcatat aatcactcca ctaattaatc tccccaaaaa
    16741 gacacagcat taagagatat accaacacaa cagtgcaaat aactctacat cttccttcgc
    16801 aaccttattt caataaacca taaaaattat tttttaatag aaactgaaaa ttaaaactag
    16861 aaaaagtagt tttaccgaat gtaagagcat catcaccatc aatatagaaa tacattcttt
    16921 tccagttaca tttaattttt aaacaaaatt ctccccaaaa aggaactttt tctagtgaaa
    16981 acttggtaat ctctttgtaa ttaattcttg ttaaagaata attaaacact tcatttttac
    17041 ttgttatttt ttcattgact ataactagtt catctggtaa aaaaattaac caacaaacat
    17101 cgacaaacag taaatgatat aatccatttc cacctccaag catattcaat actggtgaac
    17161 atgccttaga aacacgaata tagttatggt ttaaatagat attttcttta aacattgctt
    17221 gtttaaaagc catatgctct tgttctaaac ttttcataaa cttttactct aatgcacagc
    17281 tagcagcagc tgctgcaatt cctgctacaa tatttacctt agctaactct ttagctgcag
    17341 cttttcctaa ttgtttttct gcaattttta ataataaatc cgcagctttt tcaaaattaa
    17401 aagcttttaa tgcttcaata aaatctccct gcgtacctat agcccaagcc actcctcctc
    17461 caggaagaga attaatggct acacatccag catatcgttt ccaatcaact ttctccattc
    17521 taggaacaat aatatgttca taaaagactc ttgctgctct tccttgttcg ttatcttgac
    17581 tgattcgttc acgaatagca ccaaaatcct ttatatggta tacaccatgt tcgtctaaaa
    17641 aaccaactgt atcaaaataa aaagttaatt catctactaa tttattcttt atttctaaat
    17701 caactgtatt cactttttct gtggcataca cacttgttcc agtactaaca aaagtactta
    17761 aacctaataa gaaaacacct aaaacaccaa atattttaat tattcttttc ataatttctc
    17821 ctccataaaa aataagttac tttttaaata tcttgtttat gaattcattc cccaaaggcc
    17881 ttttaagatt gatacagcag tccgttcact tcttttagac ttgtcataca agtcttttaa
    17941 atgatcccat atcagactag tttgtctatc tagcttcaat ccattaaacg ctaatgaacg
    18001 gttcattttt tctattactt tagataaagc tacagaaatt tttatacctt cacaacgcgc
    18061 atcttggatt tcaataatag tatcatcaat tagtttttga atttcttgcc tatcaacata
    18121 ttcaatctta gaaagagaat cttttaaagc tactaatgat tcaacgattt cttttttctc
    18181 ttcagacatt ttcttcctcc ttctagtgac ccgtaaagcc atgtagagca gagtccattg
    18241 aaccagtaat tacactatct acaacgccat tccaatttac tctacatttt ccatttttca
    18301 gatttgtcgg tccatacgga tagccttttt gacattcaat gttcggatta taccagatag
    18361 gattatacca ttcagccgca gaagcagatt cagtcgatac aaacaatccc acaccaacaa
    18421 atccaataca catcacacta tagccaatta gttttttcat ctcgtatcca tctcctaaaa
    18481 aatagaatag ttcttatagt tattcataag acatattttt tccgtttttg ttttatcctt
    18541 tctgtcctat aacaactttt ttcaagtaaa gaatgacata gtttttctta aaaaaacagt
    18601 ctgttttttt ctatttcttc ggtgtataat aaatatgagt gttcattttt tattttaata
    18661 cgcactccgt acataataaa tcttgatcgc atcaatcttt tgagcttctt gacctacttt
    18721 caattgaagt aatacaaatt gagtaacctt attcattgtt tcttctccaa ataacaaata
    18781 ttgatccgga ttctctatat cttgtgtcac ctggtaaagt ttcccagttg ttttcatttg
    18841 tacatgcggg tctacatcaa tactattgtc tttaatacaa cgatctgtca tatagtccct
    18901 cacagcttga ttgcgtttat aaacatctgt gaaattactc cattttctag caaaatcttt
    18961 taagaaattt tttgtcattt catctatttg catttgttgc gctgtctcgt cttctaatga
    19021 accaatttga ctgttacttt cagtactttg aagagttcca cttgtttctt ttactgcttc
    19081 gattgtttct tctgtcgttc tcaattgtgt tttttgtttt tcagaagaaa accaatgaca
    19141 accagtaaga cctatcaaac ataaccaact aaatactaaa attatccctt ttttcacgtt
    19201 tctagtcact gcctttctta tttcacctta cgaaccagac tacgaatttt tgtttgattg
    19261 tacgtgcgtt gataccgagc cataatccgt ccttgctcgg cattctgttc cacactagag
    19321 aaatgttgtc cgccatatga aacatctgtt ataattccgg tgtgaccata gattccagga
    19381 gacaatgcac cacctgcttg ccaattcacc acatctcctg cttgtaaatc acttggtttt
    19441 gggttcatga ttacttgcca accataggtt gtccagttat aatcttcccc tattaacatc
    19501 gcaaacatgt gtccagaacc cattaactgt gggccaccta attgagatac ataccatgcc
    19561 gtaccaccat aacattcccc attatttacg gatcgtccaa tgatccgatc caaaaccttc
    19621 gcattgcctt tactttttcc tgcaataagc gaagtttttt ttgttggtag gctattccaa
    19681 tgcttgatcg caaaagtatc atattccgtt aagttatagg acgttatgat actcattgct
    19741 cctcgataat acggactccc ttcggtaata cctgctgccg catagcctcc acgacctaga
    19801 atcaataaac aacttccagg atctttattg cccacacatt gattaaagtt gctttggctc
    19861 gccaccataa agccataata gtcataacaa gcttttaagt tcggaaactt catatagaaa
    19921 ccaccttcag aaccaccaat tccacgtgca gaaccttgtg ggtagggaca accaggaaac
    19981 caggtaatcc caaaaaagtt cgtatcgttt cttccagatt gtgactgtcc ataagctgat
    20041 tcatagccta attgagaaag aatcacactc ggtaataact gatactttac agctgcacca
    20101 actgctgctt gcgcatgttc atctgtgatt ggaccacgtc ctttaatctc tgaaaaaatc
    20161 ggtaatcctt cggtatattc cccattaaaa gcgacagcta gacctgtagc ttctcctcca
    20221 tgctcagaaa gttctcctga aaaaaagaat ggcaatagaa aaaagggaag aataaagaaa
    20281 agaagacaac ctagacaccc tttcttcatt tcttcctcat cctttcttcg ataatggttt
    20341 ttggactgtt cgtccttttg gtaaagtaaa atcagttcct ggttttgcgt ccaaaatcgg
    20401 cagtgtttta ggatcctttt ctattttttc cgattgctct gttggcttat ctaaagaaga
    20461 aaatgcaggt tgtaacgatt ttggtgcgga aatcgacggt ttactttcag acgaacgttg
    20521 ccccggttgt tgcacagaac gatttcctga tagagtggct accgacgaat taggaacaga
    20581 gtattggttc aataactgct gcattgctgg ataactccca tttttcgcct gatttttcac
    20641 ttggcgaatc tgttgtgaaa gagaaccagc agctgttaat tgtggcacgg gtacttttcc
    20701 agaaggcaac ggaatcgatt gaccaacaaa agcgatacct ttatttaaca atggttttct
    20761 ttgattattc ccttgttgct tactcaattg tgccaatgat tgtacctgtt gttttggtct
    20821 tactgaattc atggacgaat ttggaatcaa accatttgaa agaccagaat tccactctgt
    20881 tttcgatttg gtagaagaca tttcaggctc taccccatga taacgaacat gacgaccact
    20941 ataaggcaag gcttgatttg aacgcccacc tagttcaaag ggattaacca cttgcctccc
    21001 ttttaccgat tcttgtggtg tacgtttttg ttgaaacttt tgaaatccat gtatcgctgc
    21061 agaagcgagt ggattcgttg ctcgatacac attccctgct aatcctgcac ctttgattgc
    21121 caaattttgt ccagcagttg atagttgacc aggcagttgt ttcatttgag acaaagaatg
    21181 acttgctatg tttttcgtgt tgtttatagt ttgatctgca gctcctaacc ctagtttctt
    21241 taataaatct ttccgtttta caatgagtaa aattgatagg agtgctttga caaacatatt
    21301 tcctaaaaaa ccaaaaacag tattcattgg aattaaatcg tctactatgt tatagatcaa
    21361 aaatgccacc aaaataatca cactgtaaaa agatttttga aacatcaagc ccaaaaagga
    21421 ctttaaggta ttcatgagca tataatcaaa tactggaaca aaagaagcga gtaatgaaaa
    21481 aggaatcaca agtaataaac acaacaccaa catttgaaag ataaaacgaa tcatgccaat
    21541 cactacaagt ggtaatccaa tacttagatt aagcaatggc accatagaac caacgactgc
    21601 tttataaaca gctttagttg gttgaatata gacacgataa gccttctttt tccctctatc
    21661 ttctcctgca gcagtggtca cttttgtctc aatatcagat aattcttcac ttgacgcttc
    21721 cttggctaga aattcttgtg gttcaatctc tgcttgatac aattcttcta aatttgttgt
    21781 cccataattt aacaatatat acggatcaac aacagccgct ttataataaa gttggcgcac
    21841 tttttgaatg gcttcctttt gtgtcgttgg cactaaaaca ccattgacat cttttgtcgc
    21901 caattcatct agactatttg tagcagaaaa aataaagcct tctacctcca cggacaaatc
    21961 atttaaccct ttggtaaaag cttctccttt actaggtacg ttactaccat agccaaacca
    22021 aaccattgaa aaaatgacaa cgaagagaaa tcgaataaac accatttttg cgtaatgttt
    22081 ccctctaaat atacgaagag taaatagata taacacatac aagacgacaa tccccgcacc
    22141 aataggatcg tatatttttg aataaatagt atccgaaaaa gtgaaaaact ggtgaattaa
    22201 ctcgttcatt gcagctcctt catagagctt ctcaatgaca aaatcaaggc cttgccaaat
    22261 caatttactt aaactaaaga acatattcgt catcattttt agaaaatctg tgccatttgc
    22321 cccaaataac attttgccta atgaaaattc actatcagat aaataagaag aaaaggtatc
    22381 aatatgaaat ttcccaatct catagatcga ttgatccacc tgcttttctg ccgcatacac
    22441 caatccacca acaaaaagca gtccgaatcc aatcgttaaa aaaaacaaaa cgcaccattt
    22501 cttttcctta tgctttatat aagccattgt ttcacctcat ttctattgca tgattaacgt
    22561 atcctgttct tctacttgag agtgacttgt tttttccgtt gtttgtaatg cagcggtcat
    22621 ttcttcaaac aaactgtgta cattgagttt tcctacacgt ccatagggat ctaacatcca
    22681 acactgtcct ttaatcatgt ggctcatttc agctaagttc gcttcattta cttccaaacg
    22741 taaatgattc aaaatctttt ctcgctcact gtcttcatca aaagcaaaga cgacaccaaa
    22801 attccctttt tctttatctg aacctaagtc accaataaat tgtgtatcta acactaattg
    22861 attcatctgg gaacgcccca cacgtgccat tgctgcaata atactacgtc ctgcgttcga
    22921 attattaaat acccatgctt ctgtaaaata aatcgctgtt ttcttactac tatctcgttt
    22981 tccaaacatt tcacaaaaac gacctaaact aatcatcaaa cacaaagact ttcgatccgc
    23041 atctgtatat agttctggtc ggacattgtc atttggtaat ttcaaatctt ggatctctaa
    23101 aatcgttgtt ttggcattaa agtctaatcc cgggttttct ccataagaaa atcctaaacg
    23161 taaaatcgaa tcttctaccg tcaagcgtaa aaactcacca tattctcgaa cctctttttg
    23221 ttccatttgt tctaaatagt cgaccacatg catcaagcca acttgttgtc cggcttcttt
    23281 ttgaactaaa acttcttgga ttccctttaa taccgcccct tttaaaaggt gattggtacc
    23341 taacggactt aactcatcaa tcatatcctg ggctacttgt ttcgcatcta ctcgggataa
    23401 acaaacaatt ggatctaata caccataatt acggggattt gtagcatcta acgtgacata
    23461 actcattttt tgcaaatgtt ctacaaacaa agggtaatgt ttctgataat acgggtcttg
    23521 aatgagtttc gtaaaccatt tgcgcttttc tcctttggga tccacaaata aactttgtac
    23581 attcataaac gaactataca aaaagagcaa gccaactaaa aaggtcttcc ctttaccggt
    23641 ttttccagtt actgctacat gaggcgcatc aaacaacgca cctttgattc cttccgcaat
    23701 ggctagaaga ttcaaaaaga caaaacgatt tgacgcataa attaattctt ctaatggtgt
    23761 tttttctcct cgagaaccac catcccctaa tgtatcttgc cgaccaatat accagccgga
    23821 ttccatacct aattctgata ctgctgaaaa caaccattcg ccaactgctt ctacagttgt
    23881 tcggtgcttc caatgtaact gccgtcccaa tggttgccct aataaacatt tatagaacaa
    23941 ttctcgttga tcattttttg cacggtggat atggataatc gtatgaagtt gttgaataac
    24001 cgttgcacta ttttgacgaa cttcttcaac cgtttgaccg tatacaataa aacatgcgat
    24061 ccaatcgacg acaggttgcc cattatctac tcgttgcttt aaatgtttta ctaatcctcg
    24121 aacagttaat aagcgttcac taggttcttc atcattttga accaattcct tatgctctgt
    24181 tttgaaccgt tccgatagcc aattcagttt taaaccaata cctccctgtc ctttcaagcg
    24241 tggatagtga attttcattc gcaattctgc tgggaaagaa agatcctgag caaattgaaa
    24301 tagatcacaa tttctcatat tttcaggtgt ttccccaata ggcaacaatg ctaaataact
    24361 actccctaac tcatcttcta attgaagaag gcctttatgt tccttcggta tacgtacata
    24421 cgttccttga ttgtctttca gtacttccca attattttgt tcttctactt tgtgagccat
    24481 tcctcgaata tattgcagac gattgagata caacagctct ttttttacta agggacgaat
    24541 agaaaagcta taaagtaatt gtgtcacttc ttttacataa ggatcacttt cagaaaacaa
    24601 agtttccaaa tcatctactt ctaatccaaa taagcgtgct aaacttcctg ctaaatctaa
    24661 ccagattaga tttattacat catgaaaact ctccaccgtt gctttttctt tgactttgat
    24721 tcctaaaata aatgaaggac gatagacttg accttctcgt tccaacaatg tcactgtttc
    24781 ttttgcataa tacgcaccaa ttgcttgact atcgggagaa aatccctttc ctaatgtgtc
    24841 aaacttcgtc cgtaaattca ttgttcgtgg atacatcacc aactccacat cttcataatc
    24901 tgctaaaagc aacagtaaac gagccatcat ttcttttatt tcctgtgtct tttttggtgt
    24961 gttttttgaa attgttcgtg gaaaaacatg atagtaggcc cagatacaat cctctccatt
    25021 taacaaacaa tttttcttga atgcttttac tggttctttt acaagcacca atgaatttca
    25081 cctcccaata aaaaaggaac aaccagttga ttgtcccttt ttctaatcct ctaaataaac
    25141 atacttattc acaaaaagta attcttccaa tgcattgttt gataccttgt cccagttata
    25201 atacacacaa tcaccattca tcatacgaat catataacaa aaccaatccc ataaataaaa
    25261 atgcactttt tttccatcag gttttagttt tgccagtgct aacacacata aataggggag
    25321 tcctatataa aaaacaactc ctgctggtgg aaaaaaagaa atgacccaac caataaatga
    25381 acgtaaaaat aaatattcaa agattacgac caacaaaaaa gttgctgcat tgactaatgc
    25441 aactggaaat ggaagacgcc aattgcttgt aatctgttgt acgcgataag gttccgcata
    25501 aacaatcgaa taatcataag gttcccaatc cacttcacta tcctcctaat ccataaataa
    25561 tttttcaatg attttaccaa acgcatcaaa tacacgtgtt ggatcattta agaagaaata
    25621 aactgcggca cctgctgcga tagatattaa tgcatttcct acttttgatt tcataaaatt
    25681 tcgcaatccc agataaacaa ccaccattat taaaaaatag ccaccttgcg ttaatataaa
    25741 atctacaatt cccttcagtg tcatttccgt tcttctcctt tcctatccaa ccaattatgt
    25801 gttaattttt caacataata ctgatttgtt tttttcgtaa tgacaatcgt catttgttct
    25861 ttttgtaaaa gtgacgtatc accatctcga aagacgaccg ttgcttttac aataaaaggt
    25921 tttttcgttt ctttataacg caatactttc atctctactt gatcaacttt agctgtttga
    25981 ttgagtcctt caggttcttt catcatgtat gacatatctt ttgcattgtt tttcgcatac
    26041 ttatctaaga aatcttccac aaatccttca acatctttcg cttccgacgc atcaaccgtt
    26101 tcgtataatg tgtcatcata agtaatcatt cgttgttttt ctgtattctt tggtagtgcc
    26161 gtaaaataag gataagcaat aatacgacag cccttgtttg aaatagaaaa gggaagattg
    26221 agtacttgtg tgattgtcac acttgtttct ttcttactct ctggattcat cgagcgaata
    26281 tcataagtta ctttataact agcagttgga atggtttcaa tttcttttaa tccaataaac
    26341 gaagcagcag ttaattttcg aacacctgaa acacttcctg gttcttgaat aaagttttgt
    26401 gcataaaact ctttttttaa tgtttcttga cgttgttgtt cttgttcatg attatcgaat
    26461 gtattcatat acaaagcaac aaaacgattc ataaaggatt caatttcagg tgtgtacgtt
    26521 aattctgacc gactttgtac ttctttcttt tgtaattgtt ggatttcatc tttcaaaaac
    26581 gacacttgaa ccttcgtttt catggattga aaaaatgcca agccccctga aaaacaaaga
    26641 aataaaacca aacaccaaat ccatttcact gctttttttg aatggatttt cttttgcttc
    26701 ggtactttct ctgtataaac tttttctttc cgccgtagtt gtcgtttttt cataagctac
    26761 tccttctagt atgtttttac tagtacgtac gattgacaac gataagcttg tttttctgaa
    26821 aaatagtcca ttcaattacc ctcattttct attccttttc tctttctttt atatccaaca
    26881 aatccagcaa tacttgtcaa cactcctcct agaacagaaa gtgcaacatg tatttcttca
    26941 ccagtctttg gtaagacttt tgtttttcca tctgctgttt tgatttcaat attgccactt
    27001 ggaagtttct ttacaggaat cgacaaatcc tttaccaaat tcccttcact atcttggatt
    27061 aatggaatac catcttttac accaacaatt gtttgatcac ctgctacttt taatggggtg
    27121 gttggtgttg gaatatgggt caattcctct acattactag tgacaatcgg tacactcatt
    27181 ccttgagaag tattcgtcgt aatttcaccg cttggggtta ccgatactgt gacttctttt
    27241 gctggaacaa taggtttatt ttcttttgga attgcttctg atttttcaac aggttgtttc
    27301 ggttcttctt tttgttcttc actggtagac gacatcgttg gctgttccgt acttgacgaa
    27361 tcagtattct tttcagaaga actggttgtt cctgattgtt ccggagttgt gactatactt
    27421 gaatccgttg ttgttgaact atgcacacct tcttcttcga tcgaatcagt cggtaaagtt
    27481 gattcaggaa actctggttc tggtgtcact ggctcttttt caggtttctc tgactgcaat
    27541 tgttcaggtt ctgctggttt ttccgttgtt cctccattta gctctgtctc aacatctggt
    27601 aatccttccc ctggcaatgt ttctacaatt tctgacttag gtgtttctac agtttcatct
    27661 gcataaacca atgaactccc taattgaaac gaaaataatg aaattcctag tgttgttacg
    27721 actgctaatg ttgttttttt catgattatt cctccaattt tttatgcaat tcgtgttttg
    27781 ttcatagacg ccgcactaat attatctgaa cgataaaaga actcccgtcc gttttcttct
    27841 aacccaacat atggattatt tttgaataat tgaatcaata gttcactggt gttgtatttt
    27901 ggatagtttg caaaaaaata atactgtgct tgtcgcccat ccgaaaattc aacaagtaat
    27961 tcataacgat accgcttcaa tccttttcgt tgttttaaag gatctctata ccaacttgtc
    28021 catcgttcca ttcgtggata gagatagaca cgatacacat agaacaatgc cataccacat
    28081 accaccaaaa ataataatcg ccacataaaa attccccctt ttcttctacc tttcttgaat
    28141 catcgaacat tcataccctc tatagagatt tgaaaaatcc atcatcaatt gttcatataa
    28201 acgttgttgc aaatagcgat tgtttcgaat acataattct tcatagccat caatcacttg
    28261 atcttctttt tcatagcatc ttgtagctct atgacgctca gcttgcaaga cataaccaaa
    28321 ctctgcacca tatcgttcta ctgttaataa ctgttgacta cgcaataatg caatataaca
    28381 atcacaaaaa tgttcaaccg acatttgatt tttctcacgt ttgtgaaata ggtattcttt
    28441 agaaagcaca ttattcgtta aacaatctga taaatagcga taatctggcg gtcggttatt
    28501 ttcatctgtg aatttttccc ataataaact gatttttatt cgttcagcgg ctagatagtc
    28561 ttgttcgcgt ggataaaatt catcaatcgc acaaagtttt ttatcacctg aataaacaaa
    28621 tccatataat gcgaaacgaa ctcttccttt tcaattggct ctcctaaaaa ttccagtgac
    28681 ataccatctt ctccttccta aaaaaaataa aaaagcagaa accgatttgg cttctacttt
    28741 tctttccttt tatagctctt ttttacggaa gaatccgcaa atgacatttt ttcaaaaaat
    28801 caatcggcac aagttcacga aaacttggag caattttgga tagaatcact tccccatctt
    28861 gtaaaataca atcataaaaa tcatcagtta cttgatactt acgcttctta caataattga
    28921 taaaatagta gcgatcattt tctatttcca ttcgttgttc tactaagcgc atacgaacat
    28981 catcatagaa ataagccaca aatcgccctt caagttcatg tttttcaatg ggatactctt
    29041 ctggtaacaa tctatttttt cgtcgtttat acattgctgg ataccttaga agaagttcat
    29101 ctaaacgtct gtcagtatat ggtaactgac gaatcaacga ttctaatcgt tctttataca
    29161 gatagaataa ttggcgcaag caatagtgta ccgcctctgg attttctaat actgttggat
    29221 cacgtgacca atacgcacca acataaatca taattttttt catttagaca atcacaccag
    29281 caatactaat gaccgatcca caataggtag aacaagtggc atagcgacca atttcctcta
    29341 attctatctc aatctcttct aaagaaagat atgtctgttc ttctgttggc tggcgactca
    29401 tttcccaagt gacagtcacc aatgaaattt cttccataag aggtttttcg ctgctaagtg
    29461 ctgccacaca gttttcatat atcttcattt tatcgcagcc ttttttaacc gctaaaatcg
    29521 caggtattgg caatgaaaat cgataaaagc gaatgaattc tagccttcct ttccttcggc
    29581 taaattccaa ctcttcgagt tcttgttcgt atcccttacg aacttctaat aagcgtgcaa
    29641 tttcttgcca gttctctttt tcctgataac gtccagcttt taccgcttgt tcaatataag
    29701 gaactcgaaa acgaaaataa gacaaatcaa ccatcttttc atttaatgct tcgattgcag
    29761 cctttaaatc caacaggcgc agccattctg ttgtcgtata tgcattcatg caattttccc
    29821 tcctgacgtt cccatccatt ctagatagtt ttgttgctcg tcatttagtt cggcattatc
    29881 aatcccttct tgtacaaagt ctcttcctaa aatacgatct gcttcttgta acaactttaa
    29941 tgtcggagct acttgtttca aaaaccagcg ttctgaacga tctaatgaga atttttctgg
    30001 ctttactgta aaatccaatt cttccatcga acgaaataat tttgcccatc gtttatcaac
    30061 aatccgtgca tcactttcca gtctatccca aacaataagt tttgcattaa ttaaaccaac
    30121 gccaatctct cctaaacgtt tcggtgaatc acctaaaata aatgcttcta ctgcttgtgt
    30181 tgctttctca ttggctaacc gtaactcata tcgattataa ataccatatt tcgttaatgc
    30241 ttctaattct gaaatttttt ctcggttcgc aatttcaaaa cgtttctcat aaaaattaaa
    30301 aaagagagga ctctttcgcg atccaaaata caaagataat ccttcacttc gaaaatagcc
    30361 atcatctaaa aaacaaccgc caatattctg gaatctctta aagtccattt ctaataaacc
    30421 tgctttttgt ttttctagta attcaaagag atcgaaatgt tcttccgttt ccaatcccca
    30481 aagttcatct aacgcaatat cgaatcggct acattgcaca cgtgtataac cagcttccaa
    30541 ctttccttga tttttccaaa tggaatatag ccatgttcgc caatctgttt gttgttcacg
    30601 catgacttcc tcatattccc ggcaaccttg tcctgaaaat tgcacaagta cattttctgt
    30661 tacagttcgt tttgaatgcc agaacaccca gatattccca cgaacagaaa gacagtcaaa
    30721 aagatacaag cccgttggac gtgtttcaaa ttctgtcaga tccattcgta atacacgttg
    30781 aatcactgtt ttgtagtctg tcccaaaaaa ggaaagacgc aaataatcaa tcattgctcg
    30841 aagatctatt ccgcttttca tatacaatcg aaagcgttcc ttgattcgtt gttcaaaatc
    30901 ctctgggatt tttcttttcc cttgttccat ctttctaatg taatcttttg agcagcccat
    30961 caattgcgca aatcttgctt gtgatagcgg ctttttatct ccacttatat tatgaattgc
    31021 acttaacttc tttctgtagc tttttagctc aatcggtgtc attttctcgc tccttttata
    31081 aaataacaaa atcgattttt ttaacccttt agaaacaccg atatatcaac tagtccccct
    31141 cgttttttgg gaaaagtagt acaactgctg accttagata atcacttgat acaaaagggt
    31201 ttataaaact tttttctatg tgttatgtta tttctgcccc ccatattata tatcgggggg
    31261 ctttacacaa agaggccgtg cgcaagcgca cgacctcttt gtgagctgca cacgctgcta
    31321 gcgagtgcgc attataggcc catgcttcgc agccttaatg cgcaccgcca ggcagagtgc
    31381 ggctaccaga ctacgtctag agccctcccg atagataata actacaaaat taaatgatct
    31441 aattttgtta tttcactata tttttcagga gaaaaaacgc gataaattga caaagttaaa
    31501 tcctcttcta aatctactcg ataatgatac aatcgagtca atcgttctat atcttttttc
    31561 gttagcaata cttgattaat aacttttcct gtaaaaacac gttctttgcg caaaaagcgg
    31621 taatcagtta cttgttcaat acgattcaac caatcataaa acgttctgga agaaagagaa
    31681 ggattaatca ttcgtattgc tgtagctact ctataataac aactctctgc catttaactt
    31741 cacctcctta gttgattaca aaatatgcgc atcagaaaaa cttgttcctt ttggatcttt
    31801 tgctaaatac atttggcgct ctagttgttc ttgtaacaac tgattatcat ctcccatcgt
    31861 ttgatcttga ctatcctctt ttactgtaaa atcatagaca atcatttcag taaatttctc
    31921 aaattctttg ataaagtgat aatctttgta aacaaatggc gcaaaaaact ctacaggtac
    31981 atcaaatcct ggaaaagcat atccacgacc aggttgatct ttgttgtaaa atggcttatt
    32041 tttaaaatct tctccaaaag tcattaaata accaatggga gacaatcgac caacagaaat
    32101 acggaatgtt aaattatccc gaacaccact tggaaaatat tctgcatctg gtcgttgcat
    32161 tgctaaaata atgtacatcc ctgcttgacg accctttaat actaatggct gaatcaattt
    32221 atcgactcta tttctcgctt ccatatccaa cgaaccataa aaagctgccc attcatcaaa
    32281 aaagataaaa tgcggtggta acccataata agcataattt ttccctggtt catatttagg
    32341 atctttcatg gttttcatat aggcataccg ttgattcatt tcttttaatg catttcgtaa
    32401 acaaataatc atttcttcat ttattttgta aaacacatgt cctttgaata catcgacgtc
    32461 acctaatgct gctaaatctg ccgcttttcc atcgcaaata tctactgtcc caacacttaa
    32521 acaagcttga attaaagaat acaataaata ggttttccca ccaccgattg caccagcaat
    32581 caacatattt ggtgattgat catataccca atccaaagtt ttcattaaat gaatacgtcc
    32641 attttctgct atacattgat caataggaat ccgaccagaa tctgaaagga atacataatt
    32701 gattcgggct ttttctcgtt cttcacgaat taaatcacgc aaaaatactt cagataacaa
    32761 atgacccatt tttaaaaatc gttcgtgaaa acgcccacca tctaaaggaa aagaaaccac
    32821 taattcttgt ttcttttgat aaaaataaac ttttggtaat ctcatttttt cccttgtttg
    32881 tttctcacta acttgtttct ttgtataaac aaaccgattg tcaattaaca ttcgaacaag
    32941 taactgacgc caataaacag aggcaaaata tccttctttt agtcgcgacc aatgcatcaa
    33001 ccctaaaatt aacccactaa ccagcaacaa atacaacaca atacttattc caggaataag
    33061 atacatttgc caattcgaaa acgtacttaa acgtggataa aatactttcc aactaaacca
    33121 acctaacaga atcaaaaatg gaaacaaaaa gaaaccataa tagcaaaacc ataaataacg
    33181 attgaaatag cgaattcgcc gaccacgata cttgaaaaaa tgagctttca attgtcacat
    33241 tcctcctttc tgtttttact tttcctgtgc taaaaacttt tgacaaaaag caactaatac
    33301 aggaatatca catttagtaa aaaaacataa tcgaaaaaga tttaatcgat ttttataagg
    33361 gtgtgcacac atattacata ttcgtactat acgaatccaa atcacttcct gatgatcttg
    33421 tttccactgg tacggtaatg aaaaacgaac aagatcacgt aaaaacatac actgcccaat
    33481 aaccgcacaa atatatgcat ttgtttgtac aaaaatcgtt ggattgtctc caaaatactc
    33541 aatcaattgt tggatatttt gataacaagc acaatctctc aaagtatttg attggtttta
    33601 tctgaattca aaatctcccc ttccttctat cttagataaa aagaatagga agactccttc
    33661 ctattctttc aaaaaaacct tattttttct ctttttcctt agaatcaaca cttggttgtt
    33721 tttgatctaa acctttttct tgtgattgtt tcatattagg attatttgtt ggagcttcta
    33781 ctttctctaa tcctttcgca taaatcacta aatctgaata ttcacgattg ccatcttgtg
    33841 ctggaatata taccacatga tattctggat caattaattt cacaggatca cgtcgtttaa
    33901 aaccagtcaa atctacatct gctggaaatt taactcgtcg tgcaatcttt ggttcatctg
    33961 gatttccaaa aactaattgt gctcgctgtg atcgaatttc tcccgtataa tcgcctgttt
    34021 cattatcaaa tacacgatca gactcttcta atgcgccaaa gcgtacggct cctaaacaag
    34081 tttcatctaa tgcttctgta atgtcataat tatttggaaa ttttaatccc atcttacaaa
    34141 acctccccaa tttttacacc agttaaaaag acaccaacat cttgatagcc agttgttcga
    34201 cgctctgttt gtcccatatc atttgtttca cgactattca ctcgttcttt acgaaaaaca
    34261 aaataagctt cttcaaatga aatacgcacc tctttttctg gtaatcgtaa tcttttatcc
    34321 tcttcagctg tgagataaac aaaaaaagca ggctgttctt ctcgcgaaca ctctgcttgt
    34381 aattgaacat atcgcccaga cacaccatta atttcctttg gtggattagg ttcccgtgaa
    34441 cccaataaaa atacttgacc taaaaactct ttcttcatac gcaatgcttt ttctgccata
    34501 aagtttttcc tcctcttaaa aaccaaaata aattctaaat atttctacat tacaatcaaa
    34561 caagcggtta aaaatcctaa ccgcttgttc ctcatgacta atctttggct ttacgtactt
    34621 tataaagtgt tatacctaaa gcaatgacta atactactaa tccaagaacc ataagtatac
    34681 tacttgtttg ttcacctgtt tttggcaaca ttggtacaac agtagctggt ttaacccgtt
    34741 gttctggttt cactggttgc ggtggttttg gcgcttccac aatttgaacc gtttgatctt
    34801 tgtttgttag atctacattg tgtttcgcca cttcttcaaa cgtttctttc tcatcttccg
    34861 ttttcgcttg gagccattcc gcaaaactca agccttttcc tgcaagattg cgaccgtcca
    34921 ctaagaattc aaataagaat tccatcattt ctttatcggc cgcaaagact ttttccgcat
    34981 gagtgccttc aaatggtgtg ccgtctggtg ttaagtagcc ttgaacaatt aagcgataga
    35041 tttgaccaat cgcaagaccg tctactttga cccattcaag cacagtttga tttggcaagg
    35101 ccaagatctc ttttccgcca tttttattcg tcgctttcgt cgtaatggtt ggattactga
    35161 ttttgatggt ttggtcattg tcggtaatat ctgcgtgaga agccaataat acgccttctc
    35221 taaacagatc ttcaaagacc acgacttctt tgcctcgcaa cgcacgtgcg tctagaataa
    35281 agtctagatt gactgtacca tccgttgttt ctgccacaaa cgttaaggta cttgtgactt
    35341 cttttccatc tactagcact ggtttttccg ttactttgtc cattagaaca ccgttgactg
    35401 tgtatgtttt tccaacgacc aaatcgtggt atttcacagc gtctgtaatg gtgactttcg
    35461 ttaatggatt aacctctttc aagccagtgg gtttatgtgt agccgttgta cgtacacttg
    35521 ggttagttac tcgtaccgtt tgccctttgt cgttgatgtc tttatggttt gctagttctt
    35581 catcatttct aaaaagactt tcaaacacga cgatttcacg accatttata cctgtcaaat
    35641 caaaggtaaa tggtacgatc accgtttcat tttctgcttt ggcaataaag ccaacactcg
    35701 tttctaccgt atttccatgc acaagcaagg gttcaccggt tgctttatcc attaagatcc
    35761 ctttgaccaa gtatgctttt cctggaagaa tctcggtaat ttcaacggta tcgtttaagg
    35821 taaacaatcc tgttgggtct gcgactgtca atccgtcttc aaagacagcc gtggtatgaa
    35881 cggttggatt attcactttc acactttggg cttcatcgtt gatatccgca tgtgctgcaa
    35941 cttcaatgcc atcacggaaa agtttttcaa aaacaacgat cgtttgacct ttcagaacac
    36001 tagcattaac cacaaattca aggtcttttg tgccattgac tttgtctgca ataaaggcca
    36061 aggtacttgt gatttctttg ccatcttgta aaattggcgc attcgttgcc ttgttcatca
    36121 atactcctga aatggtgtat tcttttccga caaacaagtt ggtataagaa acactgtctt
    36181 taatgacgat cgtttctaat ggatcaacca ctttttcacc atcggcttta tttgacgctt
    36241 gtgtttctag ttttggtgga atcaagtaat tacgtacaga aaccactaac gtttccccat
    36301 catctggcgc attttgtttg aatgcaaccg tgaatgcttg tttatctgta tttggttgga
    36361 aactttctaa tggggcattt tccaagaagt aatagtcatc ggcaactaga cctttcacta
    36421 aaatttcccc gttttgatca gtggtatatt caccaattgc ttgattttta ccgttataca
    36481 aggtaaagtt cacacctgcg agcggcgttt tcttcttgtt ccattcttca tacttgaata
    36541 attttacact tttccgtgct tgacggttcg caaaatggat cactttgatc ggttctgtat
    36601 cattggtaat cgagaacact aatgggtttt gattcaaaac gtaatttacg ggggctttga
    36661 tttcttccaa acgatagcga tcttttccat aagtaagtgt accgttagtt aggaaaaagc
    36721 ctttttcatt ggttttaaag atatccgttg tttctgtatc atttggaatc tccattgtga
    36781 cataacgatt ggctaaagta tcaaaaatct tgaattctgt attagcaagt ggaatcactt
    36841 ttcctgtttc ttgatccact ttcaccactt taagacgttg ttcaattact ttatcttcta
    36901 aaacataatg gaaagtttgc ccattttcag aaattgtgac ttcaagtggt tcaaatagtt
    36961 tatacccttc ttttcctttg gtttcagaaa gaatgtacgt atcaaagaca acggtatttt
    37021 taccaaaagt agcataacca tcattgtctg tcacaacggt tttcaccact ttgccagttg
    37081 tttttgacgt caaagtgatt tcaatgccag ctaattttgg tttgttatct ggattcgttg
    37141 aatcgactaa atctttatta gcaactttca ctaaatcaat ggttcctttg atcacttgat
    37201 cttttgcggt cgcattgaca gtttttccag gttcaacaac aatttcaatt gcttcatcag
    37261 aaagcacata accttttggc gctttgattt cttttaaaac atatttgcca ggatcaagat
    37321 ctttaatttc tgcctgtact ttgccgttaa tttttttcaa ggtaatttct ttaatctttt
    37381 tcccatctgc ttgatacaaa ccatagaccg cattttctaa agaagctgca ccttgtgctt
    37441 tcacaccagt ttccgcatct tctttaaaca cacgaatgtt tccttgtttt agaatttgta
    37501 aattaataac agacgcatta ggttctgttg gatgtaacac accaattgtt tgagctcctg
    37561 gacgacgata ggctaatggc gcaccttgaa ctttaatttt attcaattga atttttgctt
    37621 tatccggtgc ctcttttgtg actgtaatcc atacttcatt gccgtgaata gatacattga
    37681 caccttttgg tttttgaatg tctttcacat atttcaaaaa atcattttta ttctttactt
    37741 tcaacgtttc gccaattttt accgtatgtg tttgattatt aaaagttgct ttttcaccaa
    37801 agttattaat caaacgttga atttctgctt ttcgacgatc ataatcaaca cggatatttt
    37861 tgattgggat ttttgtgccc aaagcttccc aaatcataaa ttgtgccgca atgtattgtt
    37921 catcggattt gtctttattt gtgacatatc ctaaataaga gatcaagctt gtttttttcc
    37981 gtacatttga atttttcaaa tagtttttca aagcagtagc tgtataaact tgaccttctg
    38041 cggctgagac accaggctca atacaaaacg ccacttgtcc attaatctca aaacgaacca
    38101 tataatttaa agtgaagttt agattgttcg gactagaagt aacaccaata ttttcgcccc
    38161 aatcaatttt ccgaccacct aaaacagctg cattggttgc acggcgaaca cgaaccgaac
    38221 gattggttgg tactgttact aacagtgtag gtgtacctgt ttttggaatg ttctgctctt
    38281 ttttcttttg attttcaata ctagccgtag attctttgtt tggtttcgtt ggttgatttt
    38341 gactagctgc ggttgaagag attgtttttt caacgttttc ctcatttttt ccttctttgt
    38401 cagcagtagc cgctggttgt tccactgttt cttctattcg tttcttttct tccgcttgtt
    38461 tctcagaaga ctctggctgc acagaaggcg ttgcttcggc agctttttct ccttctagag
    38521 tggacgtttc tgaagcaggg gttgtaattg aggcagtttc ttcaactggt tgtgaagtac
    38581 caggactatt ccctgggtgt tgtgtttccc caatcgtctg atcgagagtc gttttggaat
    38641 tgaccgttgg cgcttctgtc acaggggcct gttcaacagt ggcttcacca gctgggaccc
    38701 cggcttctgc tggttggact tctgtcactt cagaagcgac ttgggcaatg gcttccatcg
    38761 taggttgtat agccgtcgtt tcttctgcat gtgcttgagc agttcccacc aagaaacaga
    38821 attgagaaaa agccaccaat gcgagtgctt tcaaccaatt cattttcgtt tttgcataca
    38881 caagaattcc tccttttcct gagaatttta tataataaaa caaaacgccg ttaccaaaag
    38941 tgataacgac gtgaactgtc tcttctattt ttatctggcg ctcttatctg aacacatttc
    39001 atcaatgatt ttaccctccc actataatta cagaacaaaa aaagaacctg cttcgtggaa
    39061 atcaactgtc catttcccaa ttggaatacc agcttttttg gcaacttcac catcaccaaa
    39121 tctcatgcca taccaattac taccttcatc cttaatttct ttccaaccat atgacatagc
    39181 ttcatctaat gaatcaaaaa tcatgacact attgccaatt gttacaggat ctggcttaag
    39241 atcttctgga agagaaatat caatcatacc ataatgatcc gattcctcag tattattgtc
    39301 attactagct actggtttgg ttgttctact ggcttatttt gatacaacaa gtactcttat
    39361 tcttctttta cttctccgtt ttcaatttcc cattcaaacc actccgcaaa gtcttgctta
    39421 aaaccatcta ctcgatacct attttgtaaa taggcatctt ctgacgtcgt aggatctaaa
    39481 taggtaggtt tattctctgg acgagcatag acacctaccc atgtttcgta atctccttca
    39541 aaataactat ctaccaaata gccttttttt ctaagaatct cccgaacttg atttttaatt
    39601 attgatactt gttcaaaacc atcactcatt ctatcacctc aaataactct agattctcat
    39661 aaatattccc gacaatttca atcctatcaa tgatctctaa caaatcgcta cttatgcttc
    39721 cccattcgta taagaatttc ccttccgcaa aataaatttt ccataaactt cttcatgatc
    39781 gtcccaacca atatcactct cgaaaaattc cacgttgttc ttatctttta gctcagtaaa
    39841 tgccataagt tcaacatgtt ttccaacctc gaaacaatca caccacccat caaccgttac
    39901 acgtgtgcct tcaataccta agaaactttg tcctcgtgta ttaaacacta aaactttccg
    39961 cattttttgc tcattaatta atcacgcgcg aaatctagga atcacaactt attcgcttct
    40021 tctttataaa taaaaaaact ccaataatcg gaaattacta tcttttcctc attccttttt
    40081 taaatcttca tacttcttct tatctttgtc ctaacctaat aacacaaatt ttgaagaaaa
    40141 actcagtaaa acctgattct ttttttatct tcacaacaac caactttttc ttcagatcct
    40201 tttactagaa cttgtataca aaaattgttg aatgctgata taatttgcgg ctacttgaaa
    40261 aaacgataga tgtaaaaaga taaatagaat cattttttat tctatatcag tctatgattc
    40321 attgcttatc aatcacccaa cccattcgat gccgtttttt ttagagaaat ttaaaaaaga
    40381 ccgtacgaat ctcgcattat ccgattactt ttccagaaaa gatccccaat tctgtataaa
    40441 taaccctatc ttcttgttgg tttcattttc tcatataaga attcagtcaa tctacccact
    40501 atgaccatta ctacgtccaa cacaactgac atattaacca cgtaagtatt ccctcacaga
    40561 tctccgaatc tccatggtat ggattcccat cctgacgctg cagaggacaa catatttcat
    40621 gtggctctgt acccttttga tttggaaaca ctacaaatca atactcatct ataacttatc
    40681 aagcgaactt tcgctaggct tctagtgatt actaaattgt tggataacat acatagccca
    40741 ttttatctag ctgttattca taacagttag ttcttgtatt acttcttccg cttgtgttgc
    40801 cattgagctt gtcaaaaagt tacttagaaa aaagctgcca gtaaagcaac tttcaacaaa
    40861 ccctttttgt ttcttatcat atcaagaaac ctccttttat aaattttttc tataataaaa
    40921 aacgtcgata acttaataag tatcgacgta aactattttt atatcccgta aatcaaaaat
    40981 tctaaagaaa gatttcctat ataagcatat tggataattc gattagtatt gggtatatct
    41041 ctaccattct catacctatc tatggaccat tttgaaattg aaggagaaaa aagctttcca
    41101 aactcctccc tttctagata ataatctttc ctaattttcc tcatccttaa tcccatacta
    41161 aaagaattta tctttttaaa atcgctaact ctttcatctt ttggaagtat attcttataa
    41221 tcttctccgt acataaggta aggaacagtg accttaccaa gataggcaat attcattagt
    41281 ttttcaatat ctggaatatt aatacctttt tcccatctac ttataacatt tttgcctgta
    41341 tagatggtaa agtttttacc aaatttttca agcgtctctt cccggttctt tcggacttct
    41401 cgtattcttt ttcccataac aattttatcg tcttttgata aactaaatat ctcactatca
    41461 cgattaatct ccttcaaaat ttctttttca ttacttaata gaaaaatatc gatttttttt
    41521 tgcatttctt ttgacggatt tctctttcta tttaacacat aactgagtaa tacttcacta
    41581 attcctatat tatcagctaa ctctttgtta agtaacttat tcatatctct gtatgcaatt
    41641 agtttaccga tgagaatctc aatcttatct tcctcatctt ttattagagt ttctatattc
    41701 agaatcttgc ttagagtatt atctacgtct ttagggattt ttcttgaccc tttttcatat
    41761 ttaactaaag tactttgtga aatacctgct aaatcagcta actttttttg agatagtttt
    41821 ttctcttttc ttagagattt aagaaccctt ccacttgaat tatcaaccat gaaaaaagca
    41881 cctcctatga gatgctttca tcatatactg acagctaaaa atcttcaaga aaaatattcc
    41941 aattttgtta attttagtat cgccgtgata accaaatgac agtttaaaat cttttataca
    42001 gataatcctc agtgttgcat ctactcaaaa aggtttattt aataggtttt tcgattgatt
    42061 ataagttatt tcacactatc ttgctcatcc attttcagaa cggccatgaa ggcttcttgc
    42121 ggaacttcga cggagccgat ttgtttcatc cgcttcttcc cttctttttg tttctctaag
    42181 agtttacgtt tacgagaaac atctccacca taacatttag ccaagacgtt tttacgcaag
    42241 gctttgatgt ctgaacgggc aacgattttt tgtccaatag ctgcttggat tggcacctca
    42301 aattgttggc gtgggattag ttttttcagt ttttcaacga ttgcttttcc acgttcatag
    42361 gcaaagtctc ggtgaacgat aaagcttaat gcatcgactt tttctccatt cagcaagatg
    42421 tccatcttca ctaacttgct tttttgataa ccagacattt cataatccaa tgaggcatag
    42481 cctttcgtgc ttgatttcaa tttgtcgaaa aagtcaaaga caatttcaga aagcggaata
    42541 ttatagacga catttactcg gtaatcatct aaataatcca tcgtaatgaa ttctccccgt
    42601 tttcgttgag aaagttccat tactgcaccg acaaaatcat ttgggaccat gatctgtgct
    42661 ttgacgaatg gttcttctac atcctgaatc gttacaggtt caggaaaatc tgccgggtta
    42721 tctactgtag cagtcgtacc atccgtttta ttaacatggt aaataacgga tggtgcagtc
    42781 gtgatcaatt ctagattgaa ttcccgttcc aagcgttctt ggacgacatc catatgaaga
    42841 agtccgagga atccacagcg gaacccaaaa cctaatgctt gagaggtttc tggttcgaat
    42901 tgtaaagcag catcattcaa ttgcagtttt tctaaagctt cccgcaaatc gttgtaacga
    42961 gaagtatcaa ttggataaag accacaataa accatcggat tcatttttcg gtaacctggt
    43021 aaagcttcag cggcaggatt gtctgctaac gttactgtat cccctactcg tgtatcttgg
    43081 acagttttga tacttgctgt gatataaccg acatcaccga ccatcaaaaa gtctctagca
    43141 actgcttttg gcgagaagac cccgacctct gtaacatcaa atgttttgcc attactcatc
    43201 agtttgattt tgtctccggg tttgaccata ccgtccgtga tccggacatt tagaacaaca
    43261 ccgcggtaac tatcataaat agagtcaaag atcaaagctt ttagcggtgc atctaagtct
    43321 ccacttggtg caggaacata ttccacgatc tgctcgagaa tatcttcaat cccaatccct
    43381 gatttggcac tggctaatac agcttcacta gcatcgattc cgattacgtc ttcgatttct
    43441 tgacggacac gttcgggatc tgctgcgggt aggtcgattt tattgatgac tggcaggatc
    43501 tccaaatcat tgtctaacgc taaataaaca ttggccaatg tttgtgcttc gattccttgt
    43561 gctgcatcga ccactaaaac ggcaccctca caggcagcaa ggcttcgaga gacttcatag
    43621 gtgaagtcga cgtgccctgg ggtgtcaatc aagtgaaaga tatatgtttc tccatttttc
    43681 gctgtgtaat tgagttctac agcatttaat ttaatcgtga ttccacgttc acgttccaaa
    43741 tccatcgagt ctaacagctg atcttgcatt tcgcgagacg tcacagtgtg cgtcatttct
    43801 aaaatacgat cggccaatgt agatttccca tggtcgatat gagcgatgat cgaaaaatta
    43861 cgaatctgct cttggcgttc tttcattttc tttatatcca tagcgtctcc tcttttcata
    43921 taatcagcac tttccattat accaacgaaa agcagtaatt taaagagttt ttaattagtc
    43981 agctatagaa gttttttttg tagaattttg ctatactgtt atcaagctaa taaatggaga
    44041 tgaaaaaatg gatcaaaaag attttagaga aaatcttgaa ttaaaaccgg tcactcaaga
    44101 acatatcgat caattcaatg aattgctttc ctatgtgttc caagtgactg aagcagacat
    44161 cgaggaaagc gggtttgaga ataaacgagc ttttatccgt tccaaaaaac cgattttgga
    44221 agtatcgaaa gtgttcggat ggttccacga aaataaactg atctctcaaa tcgctatcta
    44281 tccttgtgaa gtcaatattc acggtgcacg ttataaaatg ggtggtgtga ctggagttgg
    44341 aacttatcca gaatatgcta accatggatt gatgcaagat ctaattatcg ttgcattgga
    44401 taatatgcgc aagaataagc aatggatctc ttatttgtat ccttacagta tcccctacta
    44461 tcggcgtaaa ggatgggaaa tcatgtctga taaactttcc tttaaaatca gagatacaca
    44521 gctacctaaa caaatcccag taagtggtat ggttgagcga ttaccagttg atcatccaga
    44581 cgtattttcc gtttatgaca aatttgccca acaaaaccat ggtgctttat tccgcagtga
    44641 ttttcattgg gaagagtatt ggcgtttcga aaatgaagat gagcgcacag ccgctgtcta
    44701 ctacgatagc aaccatgaac caagaggtgt tctgttctac tgggtagctg aagaaatatt
    44761 tcacgtaaaa gaaatgttct atcttgatca agaagctcga aatggcttat ggaactttat
    44821 ttccgcacat ttttccatga tctactgggt acatggagat atttataaaa atgagccttt
    44881 agcatttttg attgaagata gtcagatcaa agagcagatc gaaccatatt ttatggctcg
    44941 gatcgttgat gtaaaagaat tccttcaacg gtttccgttt gttggaacag ctgatgcttt
    45001 tcatttcatc attgaagatc ctgtcgctcc ttggaataat ggtgtcttcg ctttaacatg
    45061 ggatgaacag ggacaagtcc gtgtcttaaa tgaacctata ggaaaatccg ttcgactgga
    45121 tatccaaaca ttgacttgct tgatgatgaa ttatcgccgt gcttcttatt tggcaagaat
    45181 cgaacggtta gaaacagatg aagaaacact gaagtcacta gagcgtatca ttccaaacat
    45241 ggaagcttac tttagcgatt atttttgata aaaaggatga tgtttagatg aaaatttatt
    45301 ttgccgcacc aatgtttgct aaaagtgatt tgttatataa ccaacagtta gttaaagaaa
    45361 tcagagagct ctcttctgag ctttcgatct atcttcctca agaaaatgaa gcaatcaatg
    45421 acaaaactgc ttatgcagac agtcgaatga ttgctcttgc tgacacagaa aaagtgttgg
    45481 ctagtgattt aatgattgct ttactagatg ggctgacgat cgatgccggg gtagcatcgg
    45541 aaatcggtgt ggcttatgcg aaaggcatcc cagtgatcgg cttatatact gatactcgac
    45601 agcaaggcgg aacccacccg aaaaaaatcg ctgcactaca agaaacagct gaaaatcaat
    45661 ttcactacct gaacttatat acaataggtt tgatcaaatt gaacggaaaa gtggtttctt
    45721 cagaaattga gttgctttca gaagtaaaaa gatttttaga tggagggact ttcagtgatt
    45781 aaagaaatca aaaaggtgca aatagcttta cttgcttttg gtgtattcgt tgtctgctat
    45841 aatttttatg aatttatcac acaaaaatat tcgacttctc aaggaatcac atttatcgtg
    45901 gaatctttat tagggattgc attgattttc atgccacaag tcattttgaa agttttcaaa
    45961 cttaaaatac cagcagcaat cgttttgttt tactggtttt tcttgttcat ctctgtcttt
    46021 ttaggcacag ggatgcattt gatcagtatc atctcttttt gggacaaaat cttacatgcg
    46081 gtgagtccaa tggtcctgac agctcttggc tatggattga ttggttactt gatgaaagat
    46141 gctgagatat caaaaaccag tccttggttg ttcctcttat tcggctttgc gtttgctgga
    46201 ctttgcggcg tgttttggga gttctgggaa ttcttatgcg accagttctt aggcatgaat
    46261 cttcaacgtt ttgctgcttc tgatggcaca ctgtttgtcg gacgagcagc attgatggat
    46321 acgatgggcg acttgctgac aaatacgata ggtgctgcct taatgggatt gtttgcatgg
    46381 tctcaaagta aaaaagatga gcgttacttt gaaagttata aattagaaaa agtgaaaaat
    46441 acctaataaa agaggttgtg acagaagcgg gcagcttcaa gaaatttcgg cttatttttc
    46501 gaagaaacta cttctggaac actgtttatt tgaaaaaagg aggtctgaca ctagttgtgt
    46561 cagacccctt ttttctttta tagtctcaat ggaagattag acgatttctt ctagctcttc
    46621 tgttttgaaa tgaagttgtc catcaagtaa agtaatcgtt acttttgatt taggcataac
    46681 atgtcctgca acgatttctt tagctagtgg tgtttctact tccttagtga taaatcgttt
    46741 caatggtctt gcaccatatg ctggttcata agcattttca gcaatccacg ttttggcttc
    46801 atcactgatt gtcagcagga tttcttgatg ttccagacgt tgtgccaatt gcgccaccat
    46861 tttgtcaacg attcctttca cgttgtctag gctcaatggt gtaaataaaa tcgtgtcgtc
    46921 gattcggttc aagaattctg gtttgaagtt tccacgtaat agcgtgttga cttgttcagc
    46981 cactgcttct ggaatcgttc catcagcagt cacgccttcc agcagtaact gtgaaccgat
    47041 attgctggtc atgatcagaa ccgtattttt gaaatctact actcgccctt ttgaatcagt
    47101 caagcgtccg tcatctagga cttgtaacaa gatattgaag acatcgggat gcgctttttc
    47161 gatttcatcc aacaagacga ttgtataagg atttcgtctg acagcttccg ttaattgacc
    47221 accttcttcg taacctacat agcctggagg agctccgact agacgagaca cagcatgttt
    47281 ttccatatat tcactcatat cgatccgtac catatgatct tctgagtcaa acaagttctc
    47341 agctaacgct ttcgctaatt cggtttttcc gacaccagtt ggtcctagga aaaggaaaga
    47401 acctagagga cgatttgggt cttgcaatcc agcccgtgaa cgaattaccg cgtcactgac
    47461 cgcatcaact gcttcatctt gaccaatcac tcgtttatga agtgtttcat tcaatttaat
    47521 tagtttttct cgttcacctt ctacaagttt cgttacgggg atacccgtta atctgccaac
    47581 gacttgagca atctcatttt cggtaacgga ctcttgaacc atcttaatct cgctgtcttt
    47641 tgctttagct tctaattcct tcaattcttt ttctaattga ggtatcgtac catgacgcaa
    47701 tacagcagcg cgttctaaat catagttatt ttctgcatct tctaattcgt gttttgcttt
    47761 atcgatttca gcacgttttg ctgaaacaga attgacttct tctttttctg tttcccactg
    47821 catcttcatc gcatttgctt cttcacgaag ttcagctaat tcttcttgca aatttttcaa
    47881 gcgtttttta cttgcatcat ctgattcttt tttcagtgca gcttcttcga tttccaactg
    47941 catcaaacgt ctagtaactt gatctaattc cgttggcata gagttcattt ctacccgaat
    48001 cgttgcactg gcttcatcga tcaaatcgat tgctttgtcc ggtaagaacc gatcagtaat
    48061 ataacggtca gataaagtag ctgctgctac taatgcgttg tcatggatgt taacaccatg
    48121 gtggatctca aaacgttctt ttaatccacg cagaatactg atcgtatctt ccactgttgg
    48181 ttctttgact aatacctttt gaaagcgacg ttccaacgct ttgtcttttt ccatatattg
    48241 acggtactca tctaaagttg tggcaccgat caaatgtaat tcaccgcgag caagcattgg
    48301 tttcaacaga tttccggcat ccatacttcc ttctgttttt cctgccccta cgatattgtg
    48361 gatttcatcg atgaacaaga ggatacgtcc atcacttttt ttgacttctt tcaagactgc
    48421 ttttagtctt tcttcaaatt caccacggaa ttttgctcca gcgatcaatg cacccatatc
    48481 taatgaaaaa atcgttttat cttttaaatt ttcaggcaca tctttgcgta cgatacgttg
    48541 agcaagccct tcaacgattg ccgttttccc tacaccgggt tctcctatca gaacaggatt
    48601 attttttgtt tttcgtgaaa gaatacggat gacatcacgg atttcttcat cacgaccgat
    48661 gattggatcc atttttccgc ttttgacttg ctgtactaaa tcaacgccgt atttttctaa
    48721 tgctttgtat tgttcttctt ggttttgtga ggtcactctt tctcctcctc tcatctcttc
    48781 gatgttttta cgcaattctt tttcagataa tccgttttta ttcaaataaa cagttaacgg
    48841 ataatttttt aatttcatca acgctaaaat aacgacttcc gttgaaagaa actcgtcgcc
    48901 gaagctttca cgtatttggt ctgcttcatt caataatcga aagaaattct ggctgaggtt
    48961 ttgtccatat tggacgtttc caccagaaac aactggatac tcatccagta gacgatcaat
    49021 ttcatgttca aaagattcga catccaatcc ggcatccgta tagaaatttc gaccaaaatg
    49081 attagattgt aaaaagattt tccatacatg ggcaatgtcg atatcttgat gttttcgagt
    49141 gaccgcaatc tgttgagctt cagcaatcgc ttcttgaagc gtcgtagtca ttttctcaat
    49201 attcatacag gtataccctc ctaattaaag gtaagatcac ttatttcttt gatctttaca
    49261 aaaactatta tatcgctttg gtcaattttg gtcaaaatat acacatagtt ttttgacttt
    49321 ttttctcgac ttatataaat cttaaaaaaa caaaattgat tgtatgtata taaaaaaaga
    49381 gccaaacaaa cgtaaaatta tcttatccat aacgtttttc tttgatttga taaaaagggt
    49441 agatcttata aaagacctac ccttgatttt ctttattctc tttttttact tctattattt
    49501 cttctttgat cactcttcgc cgttcagcaa tcacatacac aaatccatag agaaatggca
    49561 agataaagga actgaaacga tacagtaaaa gcgaagaaac tgcgtcaact gttccaacaa
    49621 ctggtctgaa taataacaaa tagacaaatt caaaggaacc aataccagca ggcgtaggaa
    49681 taacccctga aagcactact gcaaagctga taaacgaaat ggtcagtaga aaatctattt
    49741 taggatggtt ttcaatcaga atcaaataag gaagtacata ccaaaataca agttttaaca
    49801 tattccatag ataaatccgc aatagcgcag tcctgtcttg gataatggtt tggaccgttt
    49861 cccttaaaga gtagatctgc tgattgcatg tatccaccca tttccgcaaa cgctcacttt
    49921 taaataactt attcgataag ctgacaaaaa atatttgaac attcaagctg acggacatcg
    49981 ccaataaaaa ggcaacaatc acgatcgtca aaaggatacc agcgatgata aaccagatca
    50041 ttgatggacc attagaataa aaaagagaga attggatgac caagccagct aatgcataag
    50101 tgatcactgc cagtttgtac ataatcatat ggagtgctgt cacccctgct ccctgggata
    50161 gcttcattcc ttttttgtta taaaaataaa tctccgagat cagcgttcct gtaccaaacg
    50221 aaacgattcg gtaaaacgca atatagctag aggtcaagaa cccatctttc gttgtaaaat
    50281 tcggcgcgaa aggttcagca atttctttga ttgagcgccc ttcagcgatt tggtaaactg
    50341 tccctaatat aacagccgct gccaaaacaa caacactggt agacagcaat tcggcaaaga
    50401 tatctgcaaa tgattgattg attaaataat aaataatggc aaaaatcaca atcagcaaaa
    50461 gcagattcag aatgatttta gttttcgttc ctttagacga catctcctgc tccttaatgg
    50521 aaaaaataaa tgagaatcaa atcaacaagt acacctgcag cgaatcctat agtaaacttc
    50581 tttttccgag ttttatgatg gaaaactttt cgagagatca atcctcccaa accaccgcct
    50641 aacaggctga caaatatcaa attattctca ggaacacgcc agccgctagt tctagcctga
    50701 tgtttatcat accccatcag acaaaataag taaaaattca caatgaaaag gtaaaaccac
    50761 aaaggattgt gtaacaatac atccattact cttcttccaa ctttctgtta actactattt
    50821 ctaagctttt tcttctttct ttggtgaata aactgttaat ccttttgata caacagataa
    50881 ttcaactgga agatcatctg tcgtgtctcc atccgttcga gtgcccacag atttttcctg
    50941 cgcttggatt ttcatgcgtt tggctgtgaa ataagtaatg ccggggatcg tatagaattt
    51001 gcctctcatg attctaggca aataaaaaat aaatcggaaa atatctaagg aaggtacgat
    51061 cgttacatga aattttccat catctagggt cgctgagtcg tcaaaatttg taaaaccgcc
    51121 cacggagtta gacatcgtga ctgtcaacag ttgggatttt cctttccaat gctcctcgtc
    51181 tgtttctaaa tccaaatgat attttttctt cttcagcaat aacttaaaaa acttcttgat
    51241 aaagatccac gagccgtaac gctgtttttc ttcttgactg atccaaactg ctgtatctgc
    51301 taagattccg attgtcagtg tagagataat gacttcatca ttgacttgac catagtctat
    51361 tttccgtaca ttgccttcca ggatcacgtc agcagcttct tcttttttga ggggaatctc
    51421 aagaacacgt gcaaggttgt tgacagttcc acctggaagt aatccgacat ggtattgaga
    51481 taatgttttt tggaacgctt ggacgatatg atgaatcgtg ccgtctccac ctataattac
    51541 taaagtatca gcttctatgg cttctgcttt cttgactaat tccgcatcat caatcgatgg
    51601 gccagtttca gctagttcta catataattc tggctgcttt tcttttacat aatcttgaaa
    51661 ccagcgtgct aatttctcac cctcatcttt ccctgaactt ttgttataaa aaactagcag
    51721 cttttccatt ctttacctcc tatttactct tcaaaaaaga gggcgggaca accaattcca
    51781 ttgtcctgcc ctttagcctt agacagatga cattccatca ttgggacgaa cgccttgtca
    51841 taagctgttc tttttcgatt ttaactcttt gtgttcaatt ctgcaatttt tacaatcacg
    51901 tctgttgctt tttccattac ttgtaaagaa acaaattcga atcgtccgtg catattttct
    51961 cctccggcaa atagatttgg cgtcggaata cccatgtaag agatttttga accatctgtt
    52021 cctccacgaa ctggttcgat cactggagag ataccaagct cgatcattgc ttgtttcgct
    52081 aattccacga tgctcatatc tttttcaatg atttctttca tgttgtaata ttgatcatac
    52141 atatctactt tgattcgttc ttgatcaaat cgctgattca actcttcttg gatatgtgtg
    52201 atttgtgctt tgcgtgcttc gaatttttca cgatcatgat cgcgaatgat ataactcata
    52261 gaagcttctt caggattccc atccaatgcc atcaaatgga agaaaccttc gtatccttcc
    52321 gttttttctg gaacttcatc ggctggaagc tgattatgaa aatcgattgc taactgtaga
    52381 gcattgatca ttgtatcttt tgccgtccct ggatgtacat ttttcccttg gatcgtaata
    52441 tttgcttgag cagcactaaa cgtttcatac tgcaactcac ctaaaggacc accatcgact
    52501 gtataagcaa aatctacatc gaattgctca acatcgaatt tatccgctcc gacaccgatt
    52561 tcttcatcag gaccaaaagc cactttgatg gtaccgtgag ggatagaagg attattgatc
    52621 aagatctcca ttgcagtcat gatttccgca atccctgatt tgtcatctgc tcccagtaat
    52681 gtactgccat ctgttgtgat caatgtgtgg ccttcataat ttttcaaatt tggaaaatct
    52741 tttgtattca atgtatagcg ttcttccgca tctagtacga tcgtagactc gccatcatag
    52801 ttttcaatga tttgtggatt gactcctact gcattaaaat ctgctgtatc catgtgggaa
    52861 ataaatccaa tggaacgcac ttcatgatca acattgcttg gtaatgttcc cataacgaat
    52921 ccgttatctt cattatagaa aacatcagct aagcctaact cttctaattc ttttttcaat
    52981 tcttgcgcaa aagcaacttg tgtctgagtc gatggagtcg ttttgcttgt tgcatcggag
    53041 cgtgtttctg ttttgacata tcgtaaaaaa cgtggcaaaa gattttcgta catagtattc
    53101 tctcctttta attaaattga aatgggtttg tatttgtttc agaaacgaaa aagttaatat
    53161 cccaattttc ttcttgtttc caagattcaa atttctcgat aaatcgttgc ttgcataacg
    53221 attcaatata atgaccggga tcaattgcaa tcaacccagc gctttgcata tcatgagccg
    53281 tatgataata gatatctccc gtgatataga catctgctct ttgggcgatt gcttgcggat
    53341 aaaatttttc accgcttcca ccgcaaatcg caatgcgctt cacagaggat tttgcatttt
    53401 ttggctggac tattctcagt ccatctagtt ggaacgcttc ttttacttgt tctacaaatg
    53461 cctctataga aatttcttgc ggcaattcac ctactcgtcc taacccaaac atttcgactg
    53521 gttcatctat agcgaaaaga tcataagcag gttcctcata aggatgagct gaccgcatgg
    53581 cttgaatcac ttgtttttcg atagtttccg gcaaaataac ctcaactttt gcctcttgaa
    53641 cttgttctgt cttccctact ttcccaatcg ctggttgtgc accagcttcc ggagtaaatc
    53701 gaccgtgtcc aatcgaggta aaacttgtac cggtataatc accttgtgta ccagcaccag
    53761 ctgcagctaa tacttcacgc attttctgtg catgatccac aggtacataa acggccagtt
    53821 ttttataatg aatctcatga gtctttacta aataactctc cacttcaata ccgagaagtt
    53881 cacaaaacca gtcattcagt ccatcccaaa taatatccat gttcgtgtgt gctgcataga
    53941 cggcaatatc atgtttcaac aaatctgcat acattttttc ttgtggctga tcagtaacca
    54001 gccgttttac aggacgaaag attggaggat gtttagcaat cagcaaatcg atttttttct
    54061 tgattgcttc ttcgaccact tctggacgaa cgtctaatgt catcattact cgttggattg
    54121 gcttatccaa tgttccgata tgcagtccga ctgggtctcc ttcttcagct agccactgag
    54181 gacaatagct ttcaaacttt tggatgaaag tgcgtccgct gattgtcatg gctttaaaac
    54241 ctcctcaatc atttggattt cctgctcgat ttgtttttga cgtgcctctt gattagctgc
    54301 ttgtttgagc tgttcacgga tagcttttct ttgttgaagc tctcttgtcc attttgattt
    54361 gaagatctca cttttctctt caagcagaaa tggcccgaac atcagctcca tttcattgta
    54421 agtaactggt ttttgttctt tttcggctac aatgatttca tatatttttt tattttcttc
    54481 aagtattttt tctgattgga ttttatactg attttcttgc agccaagatc gtaatgtacg
    54541 ctctccgatg tttggctgaa ggatcaaacg ttcttgtccg cttaagcgtt gattcaactt
    54601 gccagcttct aggatatctc ggatcagtga acctcccata cccgcaatcg tgacagctgt
    54661 aataccatct tgtggctgga tagcatctag accatttgca aggcgtacgg tgatacggtc
    54721 ttctaatcca tcttttttga cttgcttacg tgctgattca taaggacctt gaacgacttc
    54781 accagcaact gcatattcga tttttcctct taatatcaat gcaacgggta agtaagcgtg
    54841 atctgatcca atgtctgcta aacgagcgga ttcagggaca aagtcaccca ctgcggctaa
    54901 gcgctgagat aaatctaaat ggttcatagc ttcactcctt ctagataatt atagcatttt
    54961 ccaaataaaa taaggagact aggaataaaa aaattcccat atctccttaa aaaatatacc
    55021 ttttcgttct ataaaacaac attttcttat ttttgaaaaa atgttattgg ttatttgttc
    55081 aatgaaacat caataatcga atctccagga acttgcggtg ggatagacat cgtcatgatc
    55141 ggcatctcaa ctaatgtaaa ttggactttg tcaccgattt tcaattcatt tatgtccacg
    55201 cttatttttt cagcagtagc atttaagatc actccgtcat tgctgaatga cgttcccata
    55261 ttcgctggat cttctttggc catgacatcg acgagtttca actgaagcgt ttcttcttct
    55321 gcttctactt gagtgatact ttcaatcgtt ccgacaaata tgctttgtct ctccgttttc
    55381 gtactgcttg tttttactgt ttgacccgca tcaatcgaat caacagaacc tgtgttgcta
    55441 tctgcgctac cgcagcctgc taaaagaaaa aatagaccaa ctacagatat actagaaaaa
    55501 atagccctca taaaaaatcc tccgtttaag tttctgcatt acttgttgcg gtgattgtct
    55561 ccggtcattt ctgtccatat aatgattcgc tgacctgctt ttactactag gtcaaatgtc
    55621 agttggactt gtcaactgtt caaccattgc gtcggttgcg accagtcatt tcgatttctt
    55681 ttgtcaaata acgtatgcgt tccattatcc gtttcgcttt tagcggctct tcatctccac
    55741 gttgagtgac ggacaaatgc tgttccaatt catccattgt aaaattcgat gagaagaagg
    55801 ttggtaactg ttcctgcatc cgatattgaa ggataacacc gaatacttcg tctcgtatcc
    55861 aactactcat cgcatctgca ccaatgtcat cgatcatcaa aataggtgaa cgtttcactg
    55921 catctaactt ttctgccact tgatcttttc cgattgcctg tttcatctca acggcaaatg
    55981 tcggaaaatg gactagcgtc gtggtgaatc cagcaatcgc taattctctc gctgttgctc
    56041 ctaataaata tgtttttcca ataccaaaac ttcctactag atacagtcct ttatgatacc
    56101 cttttggatc agcagtatat ttctctacaa aatctagggc ttctaagctc gcatatcctc
    56161 gtccatctgt acgttcaaag ttttcaaaag aagccgattg aatatctttt ggcatatcca
    56221 ttgcttttac tcggcttctg atttcttctt gtctttgccg tgctaacaat gcttccgttg
    56281 gtacataagt gacatccaca taatgaaaat tcaacgtcag cttcggctca tagccgggag
    56341 cgatcatcgt tggatcgttt ttttgatatt tacgcttttc ttgcacgaat tcatacaatt
    56401 tagcgtaact tttttcaata tccgcttgtg tcaattcttc ttggtgtgcg cttagaaaag
    56461 cttgaacatc cgcatcattt aagacttcag cgatcatttc agcatacttt tcttgataat
    56521 tgcgtttgct gatgatcctc ttcaattctt tgcctacgtc ttccactaga tatcaccctc
    56581 cttttttgcc aggtattctt taaaacggcg gtcaatctct gcttttttct cgctgctgat
    56641 ctgtttttca tcttttggct ggttgaccca atcaggaagc ttttcccgtc gaacatttcg
    56701 cttgccagtt tgataatttg tttgcttctt ttgttttgat tgttttgctt gattacttat
    56761 ttgccgaatg tgctggatcg cttcttctgc tgtggcgatt ttcttttgtg cccattcatt
    56821 tgccactgta tttacataac tggcatttaa gctagcatta ttcttgatca ctagtacata
    56881 attcagcaaa acattgatca cgctactgga aagacctgat tgagaaacaa gatcttgcag
    56941 taaccagttt tcttgtttag aaacatatcc gcctttttct gacttgattg cttccagata
    57001 tttcatcggt ggaatgctct gtgcttcttt tatcagctga agcgctgcgt ttgtcaaatg
    57061 ttcgtttgac gagggttcat tactgttttc agaaaccgca actgtttctt ttgtttgctt
    57121 caccggacgt ctctgcattg ccaaaatggc ttttttcagt tctttttcag atactttttg
    57181 ttcactaaag tcataagatt gactgatcag ttcgccaagt gtcaattcat cgaaaccgta
    57241 aagctgatga tacatgtcga cttgtttgat gattggatca tcaagacttg caatatgttt
    57301 ttttgccagc caatcattca aaaactgcca atcgaatgtc gaatctgctt caagtaatgc
    57361 tactgattca gattcttcaa aagatttatt cagcgattcg atgttttctt gattagcagc
    57421 gtacactgct tcattgaagc gataaacatc taaaaatttt tttgtgattt tttgatatcc
    57481 ctctgctgta tgccttttag gttcaaagaa ttgggtaagc ttctggaatc gtcgttcacc
    57541 aactttttcc agaagaagaa aagccagaac agagtctttg aaaaatgctt taggaatgag
    57601 tggttctaac agctcataaa taaaacgagg tcccagatca ctatcttctt taaaataaac
    57661 atccagtaag ccgattcctt ctagcttttt tcttgcatca taaaattgcg ggataccgca
    57721 gcctagacta ctaagcagat ctgcatgcat cccttcagga cctttgccag attcttgaga
    57781 gatttctgat aacagggtga aatagatact caaggcttct ccgccgatta gtggctgata
    57841 aagatacagc aaggcgttct tgctgtcttc tctcagcgga gccgcttttc ttccttggta
    57901 aatatttttt ggttgaagct ctttccaagc attttccaag gaaatgcctc ctttttgttt
    57961 cttaattgtt ttctttatta ttctctttat tattttcttt tgctttatcc acgatatctt
    58021 gcaactcttt taagaaaaca gacatatctt tgaactggcg ataaacactt gcaaaacgaa
    58081 tataagcgat ttcgtctaaa tcaactaaat cttccatcac atattcacca attagattcg
    58141 tcgatacttc gttttctccg agactgcgta cgcggttttc gacatggttg acgatttgtt
    58201 ccatttgttc catagctaca ggtctttttt ctgctgaacg gatgagtcct cttaaaattt
    58261 tatcgcgatt gaactcttcg cgttccccgt ttttcttgat tactaataac ggagcagctt
    58321 caattcgttc aaatgtagtg aatcggaacg aacaattctc acattcgcga cggcgacgga
    58381 tcgcacgtcc atcatctgct tgacggctgt cgattactcg tgaattatta tgttgacatc
    58441 tgggacatct cattttgtct cacctcttgc atcgcatttt atataaagga tgtgtctttc
    58501 tttacaacta gttgtattat aacacgaaac aaatcacaaa cgcgactgtc ctacccaaaa
    58561 aacacggata taagaacaat tttttctact ttcatgcgta attgtgtccc ctgtccttac
    58621 taaatttcaa ttttccaata ctgatcacct tgattactga gaaataactt acacaaaagc
    58681 tgatttagtc atctagcaca aaaaacttga agcagatgaa caccttctca tctgcttcaa
    58741 gtcacatctc gattttttac tattttataa cttctcttcg attcctgtat agtgtttcat
    58801 tcgctgttcc tcgatttttt gctcatcggg aatgtggtca ctttctggga gcggtgtttt
    58861 actacgatca ggtgtcggat tttttcgttc ttgagtcaaa tcttgccgct tcgcttcttc
    58921 ttctgcctgc tggtcttcta tttcatcgat tcttgcttgg tactgctttt ctttttcttc
    58981 tgctgtttct gattgcgtac gaccttcatc gattagattt tctttattga gcatctcgcc
    59041 gattttttct tttgcgttac ctacgacttt atccttttga ttttttaatg atcccatcgc
    59101 tatccctcac tttctatata ctcaggatag caaaattgac acagatactc aaagaaagcg
    59161 attagcaaaa agccaatttt cgatttgtcc cacaagtatt tcttttgttc cattgttgtc
    59221 gaacaaaata tccgcacgct gctttttttc ttcgattgga agttgactac taattctctg
    59281 ctgcgcttgt tctagcgtca gttgattacg tttcatcaaa cgctgaagct gagtttctgg
    59341 cgtagtataa acgacagcta ctgcatccat atagtggtca taatgacctt cgtagagcaa
    59401 tgggatatct acaattacta aaggatgatt ggaacttaga gaggcgattt gatcttttat
    59461 cgcttttcgg ataaacggat ctaatagctg atcaagtttt tgccgttttt cctttgatgg
    59521 aaaaacaatc atcccaagtt tccctcgatc tagttgccca tcaggctgca atacctcttg
    59581 gccaaacact gatacaattt tcctcagagc aagcgttcca ggctcaacag tttctctggc
    59641 aatcacatcg ccatcgatca aaggaaatcc atgagactga aagactttgg ctgccgtact
    59701 tttaccggta gctattccac ccgtcaaacc taaaacaaat cctactttgc gatttttagc
    59761 ctttgacaat tcggacaata gtgcgtcccc ctttgtgcca cttttgtttt cacgatcggc
    59821 gttccacaac gtatacatgg tttgccagtt tgctgataga catgcagtgc tacttgaaat
    59881 ccgcctgatt ctcctaatgc attcaaataa ctgcgaatcg tggtacctcc ggcttctatt
    59941 gcacgatcca aaacatcaat gatcgataga cgtaattgtt ctacctcttt ggggcgcagt
    60001 gtgttcgccg gttgttctgg atggatcttc gcttcccata atgcttcatc tacataaata
    60061 ttacctagac cagtcactag acgttggtct agcagcaatg gcttgattgc tttgtgggac
    60121 tttttcagtc catttgcgaa atctgctaat aagaagctat ctggcaaagg ctcaggtccc
    60181 aatttcatga ttcctcggta agttgcactt gctccttttt cgacgattgt catacgacca
    60241 aattttcgta catcgttgta gcgaagttgg cttccatcct caaaaaagaa aagtacatgc
    60301 gtatgtttat cgattggtgt attttctttc gtaaattgat attttccttc cattcgcaag
    60361 tgtgagatca gttcacaatg atcgagatga aaaattaaaa ccttccctct acgtccaatg
    60421 gattggatgg tttcgccaac aagagaagcc tcaaagatgg gtgtctctgg ttgctcgatg
    60481 atcttgggcc acaagacctg aactttttga atcgtttttc ctactactaa ccgttccaat
    60541 cctttacgaa cggtttctac ttctggtaat tctggcattt tttcttttca ccttcattat
    60601 attgctctgt cttaaacaat gtttattttg cttcgtacca cgtttttccc caactgctgt
    60661 cagtgatcag tggtacatga agagaaacag cttgttccat aacttccttc accaatttat
    60721 ctaatgattc aagttctttt tccggtacct cgaagacaag ttcatcatga acttgtaaca
    60781 gcatcgtagc ttgaagacct gtttctttta atcgtttatc caattcgatc atcgcgattt
    60841 tcaaaatatc agcagcactt ccttggattg gtgtattgat agctgttcgt tccgcaaaag
    60901 aacggatatt gtaatttctt gaattgatgt ctggcagata tcgacggcgg tgatacagcg
    60961 tttcgacgta gccttggtct tttgcttcgc gtacgattct ttccatatat tctttgacac
    61021 ctgggtattt ttcaaagtac gtatcgatgt attgctgtgc tgcttttcgg ctgattccta
    61081 gattttgtga aagtccgtaa tcagagatgc catacacgat accaaaattc actgcttttg
    61141 cctgcctacg catatttggt gtgacatcct ctgccttttc gattccaaat acacgcatcg
    61201 ctgtgctggc atggatatct tgaccttcta ggaaggcagc tttcaaatgt tcatcatttg
    61261 agatatgcgc aagtacgcgt aactcgattt gtgaatagtc agaagaataa atcagccagt
    61321 ctttttctct aggaacaaat gcctgacgta tctttctccc ttcatctaat cgaatcggga
    61381 tgttctgcaa attaggatca acagagctta atcgtcctgt ttgggtcaat gtctggacat
    61441 aacgggtatg cacttttcca tctgattgga tcactttcag cagtccctcg acataggtag
    61501 attgaatttt tgcaatttga cgataggtga ggatatcctc tacgattggt gcttgttcac
    61561 gaagctgttc cagtacatct acggctgtgg aatatccagt ttttgttttt ttgataacgg
    61621 gtaatcccat tttttcaaat aagatcactc ctaattgctt tggtgaattc aaattgaatt
    61681 cttcgccggc ttcttcgtag attttttgtt cgatctctct taagcgagca gagaactcgc
    61741 ccttcatttc ttgtaagcga gtcgcatcta ctttgatccc gcttatttcc atctctgcca
    61801 aaatgataga caatggcagt tccattttcc ggaaaagatc ttcttggttt ttttctgcca
    61861 gttcttggct caattttggt gtcaacgcat tgattgcagc tacttttcgc gctaaatgag
    61921 caaaaaagag ttcctcttct tctggtaaac cttttttcgc ccctttgccg tatacagctt
    61981 catctgattg gatatcgttg tatccgtaat gagcagctat tccttcgata tctgtgcttt
    62041 tttcattcgt atcgagaagg tatgcaccta gcaagacatc aaaatcgatt cctttcgttt
    62101 ttccagtata gcggtttaaa gcaacataag ttcgtttcgc atcatatact tttttcagcc
    62161 gagtcggatc agtgatccaa gaatggaacg ctcggttttc gaatacagat agatcgttcg
    62221 tgacataaat tttcttttct gtcccccacg ctactccgac gatttcctct gtatgataat
    62281 tgtcgcccat catttccacg tacaacgcca tatccgtagt aaacatttcc tctttgaatt
    62341 catgaacgac ttcaaacaaa atatcatcca tttttacttc ttcttctacg atattcaatt
    62401 tagaaaggaa ctgattgaaa tccatttctt tataaaacgg aacgagttta tcgagatttt
    62461 tcccttcata cttcaatgag tcgatagaga catccacagg cgctgaagta ttgatggtcg
    62521 ccaatttttt cgataagaaa gcctgctctt tgtcatttat cagattttct ttcattttgc
    62581 tttgcttcat ttcatcgata tgttcataaa ttccttcgac tgagccatat tgtttcaata
    62641 gcttgatagc tgttttttca ccgattttag tcacaccggg gatattgtca gaggcatctc
    62701 cggctagtcc cttcatgtca ataatctgtt ttggcgtcaa cccatcatat ttttccgcta
    62761 catgttctgg tgtatagctt tcgatatcgc tgacaccttt tacagtgata tccactttta
    62821 cttctttact agctaattga gtcaaatccc gatcacctga aagcacgacg acatcaaatt
    62881 gatctttgtc tactttttct gccaaagtac cgataatatc atctgcttca taattgggca
    62941 attcgtaata ctgtacccct agtcctgtca acaaatcacg tatatatggc atttgttctt
    63001 tgaattcgcc aggtgttttg gatcttccac ctttgtactc cgcatacatt tctgtccgaa
    63061 aagtcgtttt tcctgcatcg aacgcaacca gaacatgagt cggttgctct ttttgcataa
    63121 cattttcaaa catcgtattg aatgcataga ttgcatttgt atgaagaccg tttctatttt
    63181 tgaaacgttc aagagaattg tgaagcgcaa agaatgcgcg aaaagccaca ctgttcccat
    63241 caacgagtaa taatttattt tttgtcatct tcttaactcc ttactgtaaa gttcttattc
    63301 attctaacaa agaatcctgc ggaatgcgaa aagaaaaagc gggaccatac caaataattc
    63361 ggtatagccc caactgatga atttttttct tttttagttg ttccgtccaa agattctcag
    63421 aaacgccaag aacaagttga taaagtccaa atacagcttc aatgccatga atacagcaat
    63481 tccactatgt gctgttccgt ttgtctggac atagatatta cggatgcttt ggttatcata
    63541 agctgtaatc cctgcaaaga tgacgactaa cagtagggag atgaacagct caactacgct
    63601 acttctcaaa atgaagatgt tcaagactag tgcaatgatc actccgatta aagctgcctg
    63661 tcctgctctt ccaaccccgc taagatctct ttttgttgtt actccgacaa cagacatccc
    63721 catgaacatc aaagtagctg tcaagaaagc ttgcgttact gttccaatat cgtagtatgc
    63781 aagagtaacc gctaatgtta tgccattcaa aagagagtag gcaataaatc caccgattgc
    63841 taagctcgga ttcttttgtg cttttacgcc tagaaccatt actaaaatca gttcaacgat
    63901 ccacagaccc acaaagccta gtggaaaatt attgataaaa gttgctaatt gcaaaggaaa
    63961 tacccaaaga gccaagtaag aagtgactgc actaagggca agtcccatac ctaaaaatcc
    64021 ataaactttt gcataaaaac gattgatacc tgacattgat gtacttggat tattcattca
    64081 attcaccttc actttcgatt gctatttcca attcaggaac ttgtggcggt tggaccataa
    64141 cgacagcatc caacacacga tcttcgttcg tattctccgc ttctacagaa atcgtcacca
    64201 catccttcat cttatctact tttatgacct caaactgaaa agtcagtgtt tcataatgga
    64261 aaaccggttc aataaaattg acagaaaaat tgacaacatg tgatcctggt ccaggaagat
    64321 gctttgaaat tgcacttgtg atgatcccca tcagcatcac tgatggaacg attggctgtt
    64381 gatattctgt tttttgtgca aagtcatgtt ggatatacaa aggatttgca tcattcgtca
    64441 atcccaaata cagcaaaagc tggttatctt caatagattc tgttaaggat aacgagtcgc
    64501 cttcctcgat ttcatttatt gtttttccta gttttctcgg cttacctatg ttcaagatag
    64561 aaaccctcca gtttattttt aatcatacat tattgtacca aaagtagcgt aaaaggcaag
    64621 ttctgctccc ttgatttaac agattcctat agtttacaga ggtcgtgaaa aagctgtcct
    64681 gcatcaaata ataagaacag ccaagaaaaa acagcttctc atgtttttga tttgattggg
    64741 cttattaccg cagatgcaag cttttgaaca ccgtttatca taagttgcaa aaaagggggc
    64801 ttggcaagat ttttgccact ccccctcttt ctatttttat aaggacactg cagtaattgt
    64861 attacagtac atttttcgtc gtgctgctta aaagtttttc atacgcttgt tcaaattttt
    64921 gaacatctcc agcacccatg aagattacta ctgcatcatg ataatctaac aatggagata
    64981 cattattttc tttgatgact tctccacctt ttttgatttt cgctccaagg tcttcaatct
    65041 taacgtttcc ttgttcttcc cgagccgaac caaaaatatc gcataagtaa actttatcag
    65101 ctaaatcaag tgcttctgca aattcatcca tcaatgcaat cgtacgcgta aacgtatggg
    65161 gttggaaaac tgcaattatt tctttatctg gatatttttg gcgtgcgcca tcaatcgttg
    65221 ctttgatctc tgcagggtga tgcgcataat catcgactac ggtcatgtct gctacgatct
    65281 tttcactgaa tcgacgtttt actcctggga aagtcagcat ttcttctgca acttctttca
    65341 gatccagttt ttcgaaataa gctactgcaa taacacctaa agcatttaag atattgtgtt
    65401 taccgaatgc tggtacagtg aagtgcccaa caaattcatc cccatgatag acatcaaaag
    65461 cagaaccaga agttgtgcgt tcgatgtttc gtgcttggat atcatcgttt tctgtgacac
    65521 cataataata aatcggcaca tttgctttta atttgcgtaa ataagcatcg tcaccatacg
    65581 caaaaatagc ttttttcact tgtccagcca ttgtttggaa agctgtaaat acatcgtcga
    65641 tacttgtata ataatccgga tgatcaaaat cgatattggt catgattgca tagtctggtg
    65701 aataggcaag gaaatgacgg cgatattcac aggcctcaaa tgaaaagaat tccgcttgcg
    65761 gatcaccatg tcctgttcca tctccaatta gataacttgt tggacggaca ccactcaata
    65821 catgagagag cagtccagtc gtacttgttt ttccgtgaga gcctgttaca gcgatactcg
    65881 tataattttg gataaaatga ccaataaagt cgtgatagcg aatcacttcc aaacctaatt
    65941 cttttgctcg ctggatttct tcatgtgaat caggaaatgc atttcctgca atgatcgtca
    66001 tccctggttt tacattatct gcgttaaatg gcagaatcgt gatatttgct ttttctaaat
    66061 ctctttgtgt aaagaaatat ttttcaatgt ctgatccttg gacatttaga ccttgttcat
    66121 gtaaaacaag agccaaggag ctcattcctg aacctttgat accaacaaaa tgatacaatt
    66181 tattttgatt ttccatttga atcctcttct cttatctagc gtccattctt ttagctatta
    66241 cattcaacac gctcctcatt atcttataaa cgattgaaaa tttcaaccaa atttatttgg
    66301 aaaggaggat tcgcttgcta aaatggtcaa gtacgagaaa aatccgtttt tattgactct
    66361 ttaattctgg tgtaagaaga ccaaacttcc tctgatatat caatgtgagg aataaaatct
    66421 tttcctttcg gaccatagcc gttctcatcg tcatggagac gttccatttc tcctaatact
    66481 agcgcatgga aatattcctt aggccattga tgattcagtt cttttgctgt aaagatgatc
    66541 tcttcagaaa agtgaaggat ttccggcaca aatggcacag cattcgcgaa aatagtttgt
    66601 tcattttgcc atactttctc aaaagttgct cgagtcctgc gttgcagtgt cggatcattc
    66661 atcaataaga ttttttctgg tacagctcct aaggaatgaa gaatctccag tgaaaaagtg
    66721 gcgttctctc cagaatttgt agacttcgat tctatcagaa aagccttatc gggcaaatca
    66781 tagacttctt ttagatactg acgacagatt tcactttcac tcatgccatc ttcaaaatga
    66841 aatccttgct tttcaaaatt ctcataaagg attctagtcg catgccccac ccctccgacc
    66901 aaaaacaatt gatctacttg gccatttaaa tacatttgtg ctgctttatc agctaagata
    66961 ggaagacagt ttccagctaa aataagtgta ggtgccgtca gttcctcaaa atttccctct
    67021 tcaggtgcgg ctaaaaaatt taatagctga ttccagtctt ttagattcct ctgctcactt
    67081 ttttccaaag gccttctatc ctttcatctg attttttgtg cttcattaaa gtcttctctt
    67141 tttgtctcaa tccatttgat ttctccatga catcttccac aacgatattt gcgtacatcg
    67201 attcttctct tgcggcagat cgtggcagaa caatcttggc atcgataata ctccatcttt
    67261 atctgtttct tcgtcaaggc tggtgcatag cgcaaccctc ctgttttttt caaaagatac
    67321 ttgaaatcca tatctttatg ctgataccct cttccagcta gatgaagatg ataatggcaa
    67381 agttcatgtt tgatgattcc tgcaatcgtc tcttcgtctg actcttcaaa tagcttcgca
    67441 ttaaaatcta aatgatgatc gtttaaatga tagcgcccgc cagttgtacg taagcgtgga
    67501 ttgaacattg cttggtgctt gaaaggaagc tggaagcttt ttaatgatat ctcttctact
    67561 aactgctgca gttcttcttg tgtcaatttt tgttactcct cattgttact cttcataagg
    67621 ggaaagcatc gtcaaactga ttctgccttt tttcgtatcg acttgttcta tccaaactgt
    67681 tacgatatct cctactgaca cgacatctgt aggatgcttg acgaattttt tgctgagttt
    67741 cgatatatgg acaagtccgt cttgcttcac accgatatca acaaatgcgc cgaagtcaat
    67801 gacattacgg accgttccag tcaattccat ccctggtttc aagtcttcca tactcaatac
    67861 atctgtacgt aataagggcg ctggcatctc atcacgcata tctcgtccag gttgtgtcag
    67921 cccagctaaa atatcggcta acgtttcttc tccgactgat aggctttcag ccagtttctc
    67981 tacggataat cgtgtcaatt tttctactgc ttcttctgta ccaagctctt tttctgaaag
    68041 ttggactgaa gttaatattt cttttgcaat agaataactt tcgggatgga tacctgtgtt
    68101 gtccaaaatg tttttcccac cagggactcg caagaatccg attgcttgtt catatgcttt
    68161 tggtcctaag cgtggcactt ttttcaattg agttcgtgcg gtgaattctc cgttttcttc
    68221 acgataaatg acaatgtttt gggcagttgt tttattcaat cctgatatat gctgcaagag
    68281 ctgcgggctt gctgtattca catccacacc tacttggtta accgctgttt ccacaacaaa
    68341 atccaattgt tcagccaaac gtttttgaga aacgtcatgt tggtactggc ctactccgac
    68401 agctttagga tcgattttga ctaattcagc taaaggatct tgcaggcgac gggcaataga
    68461 aacagcactt ctttcttcaa cttgtagatg cggaaattct tttcgtgcaa tttcgctagc
    68521 ggagtaaaca gaagcgcctg cttcgttgac gatagcgtaa taggttttat ggtcggcgga
    68581 tttcaactgc tcagccacaa aaagttcaga ttcccgactg gctgtaccat ttccgatagc
    68641 taccatatct acttgatatt tattaattaa ttggataaaa gctggtccag cagcttctct
    68701 ttttgcttgc gctgcaggtt tatgaggata aataacttcg attgctaaaa ctttccctgt
    68761 cgcatctacg actgctagtt tacatccagt acgataagcc ggatcaaatc ccaggacaac
    68821 tttacctttt agtggcggtt gcaacaaaag attacggagg ttttcgccga aaatagcgat
    68881 tgcttgctca tctgcctttt cagtcaattc attgcgcagt tctcgctcga ttgctggctg
    68941 aataaagcgt ttataactat cctgataggc ttctctgacg aatgaagaag aaggagaggc
    69001 aggatttttg actatttggc gatccaagta agctaaaatt gctgcttcat ctacttgaaa
    69061 gaatactttc agaatatctt ctttttctcc acgattagta gctaatattc gatgagaaac
    69121 cattttatgg acgggttctg caaagtcata atacatttca tatacgcctt tttcatctgc
    69181 ttgctcatcc ttgacattgc tgacatacat acctttgtta tacgtataag accgaatcca
    69241 agtccgaaat tttgcattat cgctgacttg ttcagcaata atctcatgag caccgtgcaa
    69301 cgcttcttcg gcagaagaga cttctttttc tttgtcaata tatttttctg cttcagattg
    69361 cacctctcca tctgtaagct gcatcagcca cttcgcgagt ggttcaagtc ctttttcttt
    69421 agcaatcgtt gcttttgtcc gtcgtttttg tttgtatgga cgatacaaat cttccacttg
    69481 ttgcattttc acggcttggg tgatttctgc ttctaactcg ggagtcagtt tcccttgttc
    69541 atcgattagc cgaatcactt cagttttacg tttttctaag ttttcaagat aggcataccg
    69601 ctcttcgatt tcacgaatct ggacttcatc aagacttcca gtcatttctt ttcggtaacg
    69661 cgcgataaaa ggaacagtgt ttccttcatt taacaaatta agtacagtag tcaactgctt
    69721 aggacgatag tctgaaagtt ctttttgtac aagctgaatg atcgtctggt tcaaattttc
    69781 cgtcattaaa atgcctcttt tctgctaaaa attgcttctt tattctatca tactttttat
    69841 cctgggttaa actactgaaa gaaacaatat tctctataaa aataaaaaga gccgcaacaa
    69901 agtcacagct ccttcattct ttccattagt cagattccat gccaaggtcc ttcgttgttc
    69961 tgatattcaa tatcttgaag aataccttcc ttgtcaaaaa caaccccatg caatgaccct
    70021 ccgaatacag ccccaccgtc cattccgatt ttatgatcct gaatccagag gtctgttgtc
    70081 tgcatatctc catggagcat tggtgtaatc gtatgtccaa atacaattgt cttacctgta
    70141 ttgtttttcc cttcatgaaa tggttccctt atccaaataa agtctcttag acttgtctta
    70201 cgccagtctt tctttgtcaa atccacaccg gcatggacaa aaagataatt ttcccattca
    70261 taatacaagg ggcgctggac taaaaattta atcagttctg aatatctcga ttggatcatc
    70321 atcgagattt cagttgggga gtattcctcc gatgcccctg ggtgaatcag gctttcaaac
    70381 gtttcttttc caccatttct catataaggc gcataccagt cctccggtga ttgcagaaat
    70441 tgcaaaaaat attcttcatg gtttccccgg aggtaaatgg ctcctgtttc ttcgactaat
    70501 tgctttccta ataaaaaaca ttcttttgta cgaggacctc gatcattgag atcccctaat
    70561 aaaacaagct gatggatctt tggatcataa tagtgaataa gtttttcaaa aagctcatgt
    70621 ttgccatgga catccccaat agcataaatc aatgatttca tgtggatcac catcctcaac
    70681 gctagtatag cgcatattgg aaatggtcga caatcaaaac tattgttttc tatttaatta
    70741 aagctgtaaa ccgcagttct gcttcttctg gagagattcc atggtcttga acatagcgat
    70801 tgcgcggatg tttcgcacac tctatgctac atgctcctaa atgtttttct tcattttcaa
    70861 tggaagcaag aatctgacga ttgcactcag gattgctaca attgatatat cgttcacatg
    70921 gtgttccgtc aaaccagtcg cgaccgacga tttgtttatc tacttggttg atatcgacag
    70981 cgatccgttc atcaaacaca tacatcttgc cgtcccataa ttctccttgg acttcaggat
    71041 ccttaccata agtagcaata ccgccatgca gctgtccgac atctttgaat ccttcacgga
    71101 caagccaacc agaaaacttc tcgcaacgaa tgccaccagt acagtaggtc actacccgtt
    71161 tttccataaa ttcttctttg tgctcgcgga tccagtctgg aagctctcga aaactgcgta
    71221 tatctgggcg tacagcccct cgaaaatgtc ccaagtcata ttcataatca ttccgtgcat
    71281 caatcaccac tgtctgttca tctaaaatag cttctttaaa ttcttgcggt gaaagatagg
    71341 cacctgtcac ttggtttgga tcaatgtcct cttctagctt taaacttaca agctctggac
    71401 ggtatcttac aaacatcttc ttaaaggcat gtccttcgct tggatcgatc ttgaacatcg
    71461 tatcagcaaa tcgaggatca gctttcattg ctttcatata ggcagtcgtg ttttcaacgg
    71521 ttccagacac agtaccattt attccttctt cagctactag aatacgacct ttaagatcca
    71581 aagatttgca aaaggctaaa tgatttttgg caaattcctc tggttcttcg atttttgtat
    71641 aattgtaata aagcagtact tgataatcca tgtatttctt ccttccttct tttcgttcct
    71701 aaacagtata aagaaggcgt tcgcatttga cgatttattt gcttgtgtat aattacgcat
    71761 ggaaagtttt ttgtttacat aatattatta tttgaattaa aaagacttcg ctttcctgtt
    71821 tcgcacagaa aaacaaagtc tttatttcta ttatttacct gtaaccgcaa agtagttgcc
    71881 atcgggatca gcaaagttaa agacatattc ttctccaagc tgtaccatat cacctaatgt
    71941 gactgattgc gtctgcattt ttttatatag tccaaagata tctttactgt aaaacatcaa
    72001 agatggggca ctagtagctg tgccaggtga atgggactca acaaatgctc gatcatataa
    72061 cagaaatgag gtttgactgt cctcaactcc tacttcaatt ataagcgtcc catccatttc
    72121 ttgacgatct ttttccgcaa agccaactgc tctccaaaac gttgcatttt tttctacatc
    72181 gtccacataa agcatgattt ttatttcatt cgtaaacatc tgtttcctcc taaacgatct
    72241 gttctaacat tctcaacttt gtcagtttac cataggaaaa tgggaaaatc tacgaaagct
    72301 ctcaacagaa tcgtcctact taaatacgct tttctttaat aataaataag ttggttgttt
    72361 ttgttatttg cgctttcact tttcggaata aataatgtgt atttatatgg aataaataaa
    72421 aaaagaggtc gtgactaaaa acaagtcaca acctctggta aacggtgttc tcctgacaac
    72481 tcctcggtca caagacacaa tattcaacaa acatgagaag ctattttttg aaattgctct
    72541 ttgtgactca gagtgaaacg gcaggctcac gacctctttc t
//
LOCUS       DBBGSP010000007        72239 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000007 DBBGSP010000000
VERSION     DBBGSP010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 72239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.007"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(75..797)
                     /locus_tag="ACIZE9_000547"
     CDS             complement(75..797)
                     /locus_tag="ACIZE9_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGC6092438.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(787..1524)
                     /locus_tag="ACIZE9_000548"
     CDS             complement(787..1524)
                     /locus_tag="ACIZE9_000548"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092439.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(1536..2528)
                     /locus_tag="ACIZE9_000549"
     CDS             complement(1536..2528)
                     /locus_tag="ACIZE9_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6092440.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(2543..3286)
                     /locus_tag="ACIZE9_000550"
     CDS             complement(2543..3286)
                     /locus_tag="ACIZE9_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092441.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(3360..3464)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(3527..4849)
                     /locus_tag="ACIZE9_000551"
     CDS             complement(3527..4849)
                     /locus_tag="ACIZE9_000551"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGC6092442.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(4836..5801)
                     /locus_tag="ACIZE9_000552"
     CDS             complement(4836..5801)
                     /locus_tag="ACIZE9_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092443.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(5798..7336)
                     /locus_tag="ACIZE9_000553"
     CDS             complement(5798..7336)
                     /locus_tag="ACIZE9_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGC6092444.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(7752..8039)
                     /locus_tag="ACIZE9_000554"
     CDS             complement(7752..8039)
                     /locus_tag="ACIZE9_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092445.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            8173..8841
                     /locus_tag="ACIZE9_000555"
     CDS             8173..8841
                     /locus_tag="ACIZE9_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC6092446.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(9132..9872)
                     /locus_tag="ACIZE9_000556"
     CDS             complement(9132..9872)
                     /locus_tag="ACIZE9_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092447.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(10002..10949)
                     /locus_tag="ACIZE9_000557"
     CDS             complement(10002..10949)
                     /locus_tag="ACIZE9_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6092448.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(11078..11842)
                     /locus_tag="ACIZE9_000558"
     CDS             complement(11078..11842)
                     /locus_tag="ACIZE9_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC6092449.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIQLMEEASTFLAKNLIKKYK"
     gene            complement(11846..12235)
                     /locus_tag="ACIZE9_000559"
     CDS             complement(11846..12235)
                     /locus_tag="ACIZE9_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092450.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            12370..12912
                     /locus_tag="ACIZE9_000560"
     CDS             12370..12912
                     /locus_tag="ACIZE9_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HGC6092451.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13060..13692
                     /locus_tag="ACIZE9_000561"
     CDS             13060..13692
                     /locus_tag="ACIZE9_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092452.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(13826..13951)
                     /locus_tag="ACIZE9_000562"
     CDS             complement(13826..13951)
                     /locus_tag="ACIZE9_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGC6092453.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(14085..14978)
                     /locus_tag="ACIZE9_000563"
     CDS             complement(14085..14978)
                     /locus_tag="ACIZE9_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HGC6092454.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(15160..16086)
                     /locus_tag="ACIZE9_000564"
     CDS             complement(15160..16086)
                     /locus_tag="ACIZE9_000564"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGC6092455.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(16171..16932)
                     /gene="pflA"
                     /locus_tag="ACIZE9_000565"
     CDS             complement(16171..16932)
                     /gene="pflA"
                     /locus_tag="ACIZE9_000565"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGC6092456.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(17176..19407)
                     /gene="pflB"
                     /locus_tag="ACIZE9_000566"
     CDS             complement(17176..19407)
                     /gene="pflB"
                     /locus_tag="ACIZE9_000566"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGC6092457.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(19684..22134)
                     /gene="parC"
                     /locus_tag="ACIZE9_000567"
     CDS             complement(19684..22134)
                     /gene="parC"
                     /locus_tag="ACIZE9_000567"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGC6092458.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(22146..24191)
                     /gene="parE"
                     /locus_tag="ACIZE9_000568"
     CDS             complement(22146..24191)
                     /gene="parE"
                     /locus_tag="ACIZE9_000568"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGC6092459.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(24357..24791)
                     /locus_tag="ACIZE9_000569"
     CDS             complement(24357..24791)
                     /locus_tag="ACIZE9_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGC6092460.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            24918..25556
                     /gene="plsY"
                     /locus_tag="ACIZE9_000570"
     CDS             24918..25556
                     /gene="plsY"
                     /locus_tag="ACIZE9_000570"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGC6092461.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(25688..26563)
                     /locus_tag="ACIZE9_000571"
     CDS             complement(25688..26563)
                     /locus_tag="ACIZE9_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HGC6092462.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(26645..27436)
                     /gene="codY"
                     /locus_tag="ACIZE9_000572"
     CDS             complement(26645..27436)
                     /gene="codY"
                     /locus_tag="ACIZE9_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGC6092463.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(27454..28854)
                     /gene="hslU"
                     /locus_tag="ACIZE9_000573"
     CDS             complement(27454..28854)
                     /gene="hslU"
                     /locus_tag="ACIZE9_000573"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HGC6092464.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(28868..29416)
                     /gene="hslV"
                     /locus_tag="ACIZE9_000574"
     CDS             complement(28868..29416)
                     /gene="hslV"
                     /locus_tag="ACIZE9_000574"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HGC6092465.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(29453..30358)
                     /gene="xerC"
                     /locus_tag="ACIZE9_000575"
     CDS             complement(29453..30358)
                     /gene="xerC"
                     /locus_tag="ACIZE9_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HGC6092466.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(30556..31932)
                     /gene="trmFO"
                     /locus_tag="ACIZE9_000576"
     CDS             complement(30556..31932)
                     /gene="trmFO"
                     /locus_tag="ACIZE9_000576"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HGC6092467.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(31901..33979)
                     /gene="topA"
                     /locus_tag="ACIZE9_000577"
     CDS             complement(31901..33979)
                     /gene="topA"
                     /locus_tag="ACIZE9_000577"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGC6092468.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(34101..34958)
                     /gene="dprA"
                     /locus_tag="ACIZE9_000578"
     CDS             complement(34101..34958)
                     /gene="dprA"
                     /locus_tag="ACIZE9_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGC6092469.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(35014..35781)
                     /locus_tag="ACIZE9_000579"
     CDS             complement(35014..35781)
                     /locus_tag="ACIZE9_000579"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGC6092470.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(35774..36634)
                     /gene="ylqF"
                     /locus_tag="ACIZE9_000580"
     CDS             complement(35774..36634)
                     /gene="ylqF"
                     /locus_tag="ACIZE9_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGC6092471.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            36894..37292
                     /locus_tag="ACIZE9_000581"
     CDS             36894..37292
                     /locus_tag="ACIZE9_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6092472.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            37529..38071
                     /locus_tag="ACIZE9_000582"
     CDS             37529..38071
                     /locus_tag="ACIZE9_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HGC6092473.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(38154..38705)
                     /gene="lepB"
                     /locus_tag="ACIZE9_000583"
     CDS             complement(38154..38705)
                     /gene="lepB"
                     /locus_tag="ACIZE9_000583"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGC6092474.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(38857..39084)
                     /locus_tag="ACIZE9_000584"
     CDS             complement(38857..39084)
                     /locus_tag="ACIZE9_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGC6092475.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(39081..39599)
                     /gene="msrA"
                     /locus_tag="ACIZE9_000585"
     CDS             complement(39081..39599)
                     /gene="msrA"
                     /locus_tag="ACIZE9_000585"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HGC6092476.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(39619..40332)
                     /locus_tag="ACIZE9_000586"
     CDS             complement(39619..40332)
                     /locus_tag="ACIZE9_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HGC6092477.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(40335..41231)
                     /locus_tag="ACIZE9_000587"
     CDS             complement(40335..41231)
                     /locus_tag="ACIZE9_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGC6092478.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(41389..42231)
                     /locus_tag="ACIZE9_000588"
     CDS             complement(41389..42231)
                     /locus_tag="ACIZE9_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGC6092479.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            42363..43016
                     /locus_tag="ACIZE9_000589"
     CDS             42363..43016
                     /locus_tag="ACIZE9_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGC6092480.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(43079..43606)
                     /locus_tag="ACIZE9_000590"
     CDS             complement(43079..43606)
                     /locus_tag="ACIZE9_000590"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGC6092481.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(43626..44573)
                     /locus_tag="ACIZE9_000591"
     CDS             complement(43626..44573)
                     /locus_tag="ACIZE9_000591"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGC6092482.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(44585..46468)
                     /locus_tag="ACIZE9_000592"
     CDS             complement(44585..46468)
                     /locus_tag="ACIZE9_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGC6092483.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            complement(46631..48709)
                     /locus_tag="ACIZE9_000593"
     CDS             complement(46631..48709)
                     /locus_tag="ACIZE9_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGC6092484.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(48722..48997)
                     /locus_tag="ACIZE9_000594"
     CDS             complement(48722..48997)
                     /locus_tag="ACIZE9_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092485.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(49359..49814)
                     /locus_tag="ACIZE9_000595"
     CDS             complement(49359..49814)
                     /locus_tag="ACIZE9_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092486.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(49968..51176)
                     /locus_tag="ACIZE9_000596"
     CDS             complement(49968..51176)
                     /locus_tag="ACIZE9_000596"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGC6092487.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(51288..51620)
                     /locus_tag="ACIZE9_000597"
     CDS             complement(51288..51620)
                     /locus_tag="ACIZE9_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HGC6092488.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            51768..52643
                     /locus_tag="ACIZE9_000598"
     CDS             51768..52643
                     /locus_tag="ACIZE9_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC6092489.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(52725..53306)
                     /locus_tag="ACIZE9_000599"
     CDS             complement(52725..53306)
                     /locus_tag="ACIZE9_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HGC6092490.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(53312..54571)
                     /locus_tag="ACIZE9_000600"
     CDS             complement(53312..54571)
                     /locus_tag="ACIZE9_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGC6092491.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(54573..55619)
                     /locus_tag="ACIZE9_000601"
     CDS             complement(54573..55619)
                     /locus_tag="ACIZE9_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092492.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(55854..56129)
                     /locus_tag="ACIZE9_000602"
     CDS             complement(55854..56129)
                     /locus_tag="ACIZE9_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGC6092493.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(56372..57682)
                     /gene="der"
                     /locus_tag="ACIZE9_000603"
     CDS             complement(56372..57682)
                     /gene="der"
                     /locus_tag="ACIZE9_000603"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGC6092494.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(57864..59093)
                     /gene="rpsA"
                     /locus_tag="ACIZE9_000604"
     CDS             complement(57864..59093)
                     /gene="rpsA"
                     /locus_tag="ACIZE9_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGC6092495.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(59228..59908)
                     /gene="cmk"
                     /locus_tag="ACIZE9_000605"
     CDS             complement(59228..59908)
                     /gene="cmk"
                     /locus_tag="ACIZE9_000605"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGC6092496.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(59957..60592)
                     /locus_tag="ACIZE9_000606"
     CDS             complement(59957..60592)
                     /locus_tag="ACIZE9_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGC6092497.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(60658..62061)
                     /locus_tag="ACIZE9_000607"
     CDS             complement(60658..62061)
                     /locus_tag="ACIZE9_000607"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HGC6092498.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(62048..63079)
                     /locus_tag="ACIZE9_000608"
     CDS             complement(62048..63079)
                     /locus_tag="ACIZE9_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092499.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            63110..63331
                     /locus_tag="ACIZE9_000609"
     CDS             63110..63331
                     /locus_tag="ACIZE9_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGC6092500.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(63496..64233)
                     /locus_tag="ACIZE9_000610"
     CDS             complement(63496..64233)
                     /locus_tag="ACIZE9_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HGC6092501.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(64386..65726)
                     /locus_tag="ACIZE9_000611"
     CDS             complement(64386..65726)
                     /locus_tag="ACIZE9_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGC6092502.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(65963..67486)
                     /locus_tag="ACIZE9_000612"
     CDS             complement(65963..67486)
                     /locus_tag="ACIZE9_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGC6092503.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(67864..68475)
                     /locus_tag="ACIZE9_000613"
     CDS             complement(67864..68475)
                     /locus_tag="ACIZE9_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGC6092504.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(68598..68723)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(68805..69521)
                     /locus_tag="ACIZE9_000614"
     CDS             complement(68805..69521)
                     /locus_tag="ACIZE9_000614"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGC6092505.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(69527..70096)
                     /gene="scpB"
                     /locus_tag="ACIZE9_000615"
     CDS             complement(69527..70096)
                     /gene="scpB"
                     /locus_tag="ACIZE9_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGC6092506.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(70080..70850)
                     /locus_tag="ACIZE9_000616"
     CDS             complement(70080..70850)
                     /locus_tag="ACIZE9_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGC6092507.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(70847..71218)
                     /locus_tag="ACIZE9_000617"
     CDS             complement(70847..71218)
                     /locus_tag="ACIZE9_000617"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6092508.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(71237..72124)
                     /gene="xerD"
                     /locus_tag="ACIZE9_000618"
     CDS             complement(71237..72124)
                     /gene="xerD"
                     /locus_tag="ACIZE9_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGC6092509.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT        19919 a        15222 c        12313 g        24785 t
ORIGIN      
        1 attaatcaaa cagtttactt ttatacaaag aaagccaaaa agaggtgcga cactagttgt
       61 gtcacatctc ttttttattt acctaatcta atgaaacgtt ccaagttttg ataagtattt
      121 tttttaactt cttcaactga tagctctttg atctcagcga ttgtctttaa ctgttcttca
      181 agcagtgaga cataatcttt ttctgaaaaa atccccccta aagcccactc tgctgcatgt
      241 agtccatccg tttcaataag taagtggtcg attgggactg ctttagctag ttgccagact
      301 gctggattct ttttcaaatc aagaccaatg ctgaaataac agcctaaatc aatatagtct
      361 tgttgatagt ccaaagaaga ataccaatgg atcaaatagt gattagggta agcttggata
      421 taatttaaga tctctttttc gcatcctttt gtgtgcagta caacaggttt ctcatttatg
      481 gctgcaaaag caagctgtcg ctcaaatact tttttttgtg tagtcatcgg tacattcgtc
      541 caaatattat ctaaccctat ttcaccgatg atccttgctt ttttcaaaaa aggctcaact
      601 tgttcaaacg tatagctatc tgctttccaa ggatggatac cgtaacttaa ggcttgagtc
      661 ttacttgctg caagctgtct gttttccttc cattcttctg gcgaatcaca attgatgatc
      721 gtcaaaatcg tgtgttcctg ctgaaggagt gctaaactct gactcccatc taaatgacaa
      781 tgagcatcac ttaacatcta attcacctgc caataactga taaatcgttt gcttcaactc
      841 tgattgctgc agtagccatt cacgtgaccg tcgtttttca ggcacttgaa tctcagcaat
      901 cacatgtgcc ggacgggcgg aaagcacaag aatcctgtct gataaataaa ttgcttcttc
      961 gatatcatgc gtcacaagta aagtagtccg ctttgctttt ttaggcagct tcaacatcca
     1021 gtcttgcatc tgccctctgg tcatagcatc taacgctcca aatggttcat caagaagcaa
     1081 gtaagaagaa ggattcatga ttgttcgtaa caaggccgtt cgctgcttca tcccgccaga
     1141 taattgttcc ggcaaaaaat gttcatagcc gtttaaccca aagatatcca gataatccct
     1201 tacttgttct tcattgattg ttagatgatt gattttttga tataacgtaa cgttttgata
     1261 gacgctcagc caaggaagta acatatcttc ttgcggcata taactaaatg ctgtatggag
     1321 accagttact ttttgatcgt ctactttgat cgttccagaa gtcataggct ggactcctgt
     1381 taaagttttc agcaatgttg acttaccggc tccgcttggc gcgacaatcg atgtaaaggt
     1441 atctttaggg atagtgaaat ggatgtcttc taatattttc aggttttcaa tgactacatt
     1501 caagtggctg atttggattg acatatctat cactcctatt ttataaactg attagtgaat
     1561 agttcttgcg aaggtacatc ttgcttgatc aatccgtttt cctgcataaa agctgtataa
     1621 ttgcgccaaa ctttttcttc catcaatccc caattctcag gatcatccgt ataatttttt
     1681 gacaagaatg cttgtgattc ttctaaaaac gtccgatcat tttcttttgc atatttttgc
     1741 aacagtttag cactgtcatt tggatcctta atagcttcct gatagccttt tttcgtggca
     1801 tccataaaag actgtaccaa ttctggatca cttttgatca gttgatcatt cgtaataatt
     1861 accggagtat agtaatctaa ccgttcatct aattctttca atgggatata gtttagttca
     1921 atacccgctt cttttgcttt gatcatatcc caaccttcaa agtaccattg gatatctgag
     1981 gattttccta agctttctgg cccttctcca ttgcttccta ccattgtcag ttttgaaaag
     2041 tccccgccgt ctttttccat cacagctttt aagacagctt cttcacttgg actttgccaa
     2101 cctgcatatg tttttccttc aaaatctttt ggtgaatgga tgttactgtc tgatagggtg
     2161 gcgaatccag aagtattatg tttgatcact gtagcaattg ctttgactgg tatattctgt
     2221 ccatctgcgt gagcataagt gacatcttct tgataactta caccaaattg tgctttgtcc
     2281 gcacctacta gaccaatact tgtcgaatta tctcctggtt cgatgatttg gacatttaaa
     2341 ccagcctctt tataatagcc tttttctttt gctaggtaga tgccagtatg attagtattc
     2401 ggtacataat ccaaaacaag tgtcactttt ttcaaatcct ttatttcttg tttgctactt
     2461 gtttcttttg cagtgccaca agcggataaa agcaacagta gcggtaataa aagccataat
     2521 tttttcattt gatccccttc tcttaaaaaa tataaagcat acgataatac ccttttttca
     2581 ataatgaaca agcgccattc agcaataaac tcaatagaat gacacaaatg atcgcagcaa
     2641 aaactttatc gatctggtag ctgtttttta cgcgtatcat gtaataccct aagcctgctt
     2701 gagcgcttag ccattctcca acgactgctc cgctgacaca ataagtagca gccactttta
     2761 aaccggaaaa gaagccggat aaacccgctg gtattttata tattcgataa atcttccctg
     2821 tatctgcccc catcgttttc aaaaagatga tttgctcttt tgatactttc ctcaatgtat
     2881 ccgaaaaaga aactacgatc ggaaaatagc ttatcaagac aacaaggatc acttttggaa
     2941 gcataccgaa accaaaccat agggtaagta atggccctaa caccatgatt ggcaacattt
     3001 gtgaaatcac tagtaacgga taaaaagaca tttctaaaaa cttccaataa tccattgcca
     3061 aggcagtaat aaaagaaaga acgctagcta ttaccaaacc aagcactgct tcatttaatg
     3121 tcgtgacaga atgggaaagt aatacttgtg catctgccgc taatgcagaa aatacagcag
     3181 caggtccggg taaaataaag gcaggtattt tccaaactat gacaacaatc tgccaaataa
     3241 ttaaaatgaa tgccatactg actgctggat aaagattttt cttcattttg ttacctcctt
     3301 tcttctaata tgaataacaa aaaacgcttg aaatgggcac gacatagtaa cccgcttcaa
     3361 gcgtctgcta tgtttctccc ttcaccagta ttaactgaca ggttcaatgg gtctaagttc
     3421 acaacttact ctcatgtcgt ctacgacatc cccagaaaca ggtattcatt ttttaaagtg
     3481 tagcacaaga aggaaaaagc aacaagcgct ttagttatca tgctgattat ttcaataaat
     3541 aggagagatc acttgccaat gtcggatacc ccatgatata gctatccaac tcttttttag
     3601 tcaatttttg attgatgacg agtgtcaaat catcgatcaa ttcgtctgct tgctcgctaa
     3661 tcactgcagc accaatcaaa taattttgct ggtcaaaggt caattcagcc ttagcaactg
     3721 gttcattgac acgatgatag gtgaaccaac tggtaagatc catctctacc acttgatctg
     3781 acgaagaggc gtgacttttt gtaactccta cttcagcaag tttaggactg gcgtagacga
     3841 tcgtaggtat aatcggatat ttgataggtt cgcttgttgc atccgttatc cgcttagcta
     3901 cataatttcc ttcaaaagtg gcgactggtg tcaattttgg ggttttcctt gaaacaatat
     3961 ctccacacgc aaaaattttt ggattgctcg tttgcagata atcattgact gcaattccgt
     4021 gtttatcaaa gacgatattc gcttgctcaa gtgctaaaga ttctgtattc ggctgtctcc
     4081 cagtcgcaca aaaaatcata tctgctacta attccgtctc ttttccgact aaacgatagc
     4141 gagtaccttc tgaaatgatc ttttgggttt caacaccaaa agcaaactga atgccagatg
     4201 cttccatttg atggacggct tcctctacca aagacgcctc aaattctttt aatggccgtt
     4261 gattatgatg gacaatggtt actttgctcc ctgcagcatt ggcaatcgta gctagctcaa
     4321 aagcaatata accaccaccg ataaaaatga tttctttagg cagtacaggc aatgataaaa
     4381 agtctgcact agttttcaag tattcctttc cctccactgg taagatcgta ggtctttgcc
     4441 cggttgccaa aactaagtaa tccgcatgga agacttcttc gttgacttca atagatgaat
     4501 catccaaaaa acgagcggtt cctgaaagat gatcgatttc agcttctgct aattgttttt
     4561 ttcggctttc tgggactgga tccgtaaatg ttcgtttgaa tttttgaagt tcttcccagt
     4621 tggcagttgg gatctcgtta aaaccttttc cactcaattg ttttacccga ttacgtgcct
     4681 ctactgcact taacaagact tttttaggat cacatccacg gttaggacaa gtcccgcccc
     4741 atagatcttc ttcgaccact agtactgttt tacctgcttc tttcaatcca taagcagcac
     4801 ttaagccgct cacacctgaa ccgatgatga ttgcatcata tgttttcatt tccttcctcc
     4861 tctcgactta aaaaagcaaa gatttcttta cttgtcagcg acccaatact tctttgcttt
     4921 tctactatca caatgcttgg atacaccgaa agaagcgaat atacttcttt cataggcgta
     4981 tcaaagcaaa cttgttgacg agcattttct ggtatttcat ttaagaaata tccattgacg
     5041 actaaatctt ctactcgcca ctctttcgtc tgtttcggtt catcaaagaa atgccgaacg
     5101 tagtcgtttt taggattcat caataactgc tctggtgtgt cacattggat aatttctcca
     5161 tccttcataa atgcaatacg atcacctagc ttgattgctt cttccatatt gtgcgtaacg
     5221 aaaacgatgg tcgtgcccaa ttcttcgtgt aaggacaaaa ccaattcttg taatgagttt
     5281 cttgaaatcg gatctaatgc gctaaatggc tcgtccatca aaatcacatc tgggcttgca
     5341 gcaatagctc ggatgatccc gatccgttgc tgttctcctc cagacaactc tctaggcata
     5401 cgatctcgat aaatatcagg agataagcca actttttgaa gaagttcatc tacacggtct
     5461 gctcttttct gcttttccca acctaacatt tcagggatga cttcaatatt ttgcttgact
     5521 gtcatggtcg ggaacaaagc gatttgctgc agcacatatc ccatattcca ccgcattttc
     5581 tgcagattat attcatttaa cgattttcct ttgaagtaga tgtctcctgc tgatggttta
     5641 gataatccat tgatcatttt caaagtagtt gtttttccac taccggaagg accaaccaaa
     5701 acaaagattt ctcctttttt gattgccaga tttaggtcat cgatgacata ctttccatca
     5761 tacttttttt gcacatgttt gaactcgatt aatttagtca ctgatcttcc tcctttacta
     5821 atccttcatt tttcaggaag attcgtgcta cttctgtcgg ctttttcttt tcgacattga
     5881 cttggtaatt catatcaatc atttgatcct ctgttatttt tccgcttaat ttattcagtg
     5941 ctttaacgat ttcaggatgt tctttagcaa aatctttttt catcagcggt gcgccttgat
     6001 aagctgggaa taaccctcga tcatcttcta gagtcactag atcgtactcc ttgagctggc
     6061 tatctgtgga ataggcatcc acaatattga catctccatt attgattgct tggtaacgca
     6121 aacttggctc catgctttgt acacttgaaa aattcaagcc atatgcttct tggattcctt
     6181 tatatccatc tgaacgatca ataaattcca gtgtgaatcc cgctttgatc tgatcagaga
     6241 tagctgccaa atcggaaatc tttttaagtt gatgttcgtt cgcaaaagat ctcttgactg
     6301 ccaaggcata cgtattttgg taagccattg gttttaataa tgtcatatcg aattgcttat
     6361 tcaataattc ttctgcttcg tcatatgttt tttcttttgt caaatcagca cttttcattg
     6421 cttcaggtac cttcaccaag ctttctagga cagtacctgt gaactcagga tagatatcga
     6481 tttgaccttg atccagtgca ttgaacaaaa aactcgtctt gccaaaattc ggttttaatt
     6541 caacttctgt ttttgtgttg tcttcaatca attctttata catttggatc aggatttcag
     6601 gttccgctcc taattttcca gcaatcgtga tggtttcatt tttaaacaag gcagactgat
     6661 ataaagaaac gccgccaaat aaacacacca ctgctgctaa agtaatgatg gaatatcgag
     6721 gtttcttatg ctgcaaccag cgaatcagtc cgctgaatat aattgcaagc aaggcagaac
     6781 tgatcgcacc aatcaatgtc aaaacaggtg tatttcggtc aatacctaac aaaataaatg
     6841 tccctaatcc acctgctccg atcaatgctg ccaaagtagc cgtaccgatg attaaaacta
     6901 aggcagttcg gatacctgag ataatgacag gtaatgcgat gggaagctct actttcagca
     6961 agcgtctcat tctggacata ccaaatgcta ccgctgcttc ttcaatagac gggtcaattt
     7021 cagctagacc aatatacgtg ttttggaaaa tcggaagcaa agcgtaaata acaagtgcaa
     7081 tcaatgctgg aacagttccg atccctacaa atgggataag taaacctaat aaggcaagtg
     7141 aaggaatcgt ttggagcaca cccgtgatct gcaataagac ttctgccatt tttttatgat
     7201 tggctgccca aatcgctaaa ggaatagcaa tcagtgctgc aatcagcaaa gaaatgagag
     7261 aaatggacag atgttgaaat gcagcttcca gcaactcgcc ttttctttca cttaatgttt
     7321 gtataaaatt attcatgcga ccttcctttc tgttattctt taagtataaa catttctttc
     7381 ctttttccca actaacttgt cttgccttaa ccttacagca cgaacaaaaa aaagaaaaaa
     7441 atacctctaa atatgctgac aaaaaaagaa tccaagcaac aaagtcggat caactttttg
     7501 gttctcgttt tttcactacg aataccataa aaatctatac gaaattgtca cttggaatca
     7561 gctatatctt ttttacacac acaactttta ttttaataaa aagaaacagc caataaagta
     7621 gaaatctcgt gggggagaac acctttattg gcctgttcaa cgaatattat actgtatcat
     7681 gacacttttt tgccaaaaat gtaaaaaatg gttgttttga catcataaac gtcttgtttt
     7741 cttattttta cttatatcac cactttattt tctatctctt tcactccata aagaggaatg
     7801 agttcttctt ttgactgata ataaacagct ttctcacggt tcttcatcaa aaaaagaaag
     7861 atgtctttca tagcaagtgg tgctttgccg tgttcaaata aaaagataaa ttgatttgct
     7921 ttatttatct ggaccattgt cacaggcacc agtttttgtt cttgagccaa aaaaactcct
     7981 tgatactctg tttttttggg tgattttgta agaattgtca ataagtctgc tgctcgcatt
     8041 tttccactcc ttatttgata aataaaaaga aacagccaaa aataattttt tttcattttc
     8101 ctcttgaagt aagagtataa gtcagtataa taaagaagtt gctgaaaatt ttcaaaagaa
     8161 aagaggctag aaatgaaaaa attaaattta tttacagaat tgtgcggaat cattttaggc
     8221 gcaggaatct acggattagc tgtgacagga atcaatattc catctaagct ggcagatggt
     8281 ggggttactg gtattgcttt gcttttgcat aatctttttg gattcgctcc ttctgtcact
     8341 tcactgcttt ttaatttacc tttattgctt atctcattgt ttctttttgg aaaacacgct
     8401 tttctccgga cgatcgtcgg aacatttgcg ctagttttct ttttacattt atgggagagc
     8461 cttcatatac attttgctgt agatagtcta ctgatcaata gtttgatgac aggtattctt
     8521 tctggcattg gttgcggtct cgtctttcga ttcggcggaa gcacaggcgg aacagatatc
     8581 atttatcaag ccattgaaaa atattttcat attaagattg gcaaaagtct tttcttgatt
     8641 acttttggta ttttagttgt ctccttgctt tatttggatc tcacacattt tctgtataca
     8701 ttacttagct gttctattct atcttataca ttgaataaag tgaagtatct ggaaattgga
     8761 tctgttttgc cccaattgga agcaaaacag actacagaaa catttgaacc acttgatcct
     8821 cttgaacagt tagagcactg attcttattt ttcactactt tatttaattt acagaaatat
     8881 cattatgtaa actaaaatga tattattcag taaaatcttc tttataaaaa aataaactat
     8941 ttttgcaaac gatctgcgaa aatagtttgt ttttttattt tgccattatt ttcttactta
     9001 ttgggagaaa aaattcgctt aaactcaaaa aaatttgagg atacgatata aactttcgga
     9061 tagagtataa aataaggaaa cgccgcagcg tttcctttcc aactgtagcc gaatataaat
     9121 ttgtatatca cttatttaaa atagctattt tctcccaaag agtttccttg atcatcgatc
     9181 aatccttgta atgagcgttc taagatacca tggctttttt tcgatttttt ttcttctgac
     9241 tgctttgttt cctctaacgt ttttgttcga ttgaatgttc gtacagacgg ctcaccattt
     9301 cttttttctt gatacggcgt cggttctgta tcgaacaaca gataagagtc atccgttttt
     9361 ttcatcgatt cgattaaatg atcctcagaa attttgcttt ctctagggtc tgggataatc
     9421 gatgcgggta catatttagg aacaaaataa gaacgctccc gcaccttcgt gtcaacagat
     9481 gcgtttcgtg tagtatgctt ggactctgtc cttgtttcac tttgtctgac agaacgagag
     9541 gaatcaccaa aaagtttttt tcgtcctgtc gatgtgattt ctgattggta atggccggta
     9601 taatccggta attttccttt atgcttttcc aaattttcct tacgcggagc tgacttcaat
     9661 ccatttgttg cacgacgctt gcgacggatt ttctcggtgt tcgtgttcgt gaaatgaaat
     9721 tctttcatct gttcaaacgg ggactgattc tgttcagtca aaagatcttc ttgtccgtca
     9781 aataatactc gcttcttgtc gttggttaat tttacgccta actcatcatc gtacgcagga
     9841 aaacggaaat gttttcgtct gatttctttc attcaaacca tccttctcaa aaatggaact
     9901 tttctcaata atagcacaga ttcattgttt tcagtagcaa tgcgctgatt attttaagaa
     9961 aatagcgatg aatttcataa atatatatat agtaataaga cttaattcgt tgtctctctg
    10021 ataactagtt caggaaaaaa acgacgataa ccttgactcg cccctttttc ttctattttt
    10081 tttaacaaca tttctccaca tacttcaccc atacgtataa tatcttgctt gatcgttgtc
    10141 aatttaggtg aactgatttg gtctaaaaat accccatcaa atccaatcac accaaattct
    10201 tcgggcaagt gtcctccagc atttataatc cctcttactg ctcctagtgc tagccgatct
    10261 gaactacata caaaacaagt tttatctgta aaatctgccc agttttctgt catatatctt
    10321 tctacttctg tcgaatgatt tggaaaccgc aagattttac taggaagatc aacttccttc
    10381 atcacagata aataaccagt ttcccttgaa atttcaaaag gctcgtccac ttcgataccg
    10441 atataaataa tcgtttgata atctctttct aaggcatatt gcgttgcttt tgctgtacca
    10501 tattcattat cgctgtctac ataatcatat ccttcagaat tttccccaaa caagacaact
    10561 ggtttttcca aacggtcgat ccaatcgaag tctttttttc tgacacctgt gatgatgtat
    10621 ccatcacaag aaccgacgtc gaaggcatca tttgtaacta attggagaga ataatgcgct
    10681 ttaccgatcc gtttagcgat tcccatcagc aaattcatgt aatagggctc agttgtgtcg
    10741 atttcttcca gtataaataa tttgatgatc tgcgaccgat tcgtgacaag tgcttttgca
    10801 gcaatatttg gacggtaatc cagttcagcc attgctgaga aaactaactc tttcaattcg
    10861 tcagtcacct gttccggatg attgatgact cgagagaccg tcatttttga aacattggca
    10921 cgttttgcaa catctgctaa agtgggcatg ctctcttcct ttctaacatg ttgtcattct
    10981 tactatcaat tataccaaat tttcctaaca gagtttatta tagcccaaaa taaaaaacgg
    11041 aaaatcctct atcgtcatga gtgattttcc gtttcaatta tttatacttt tttatcaaat
    11101 tttttgctaa aaaagtggaa gcttcttcca ttagttgtat ttgtaccata tgtcgctgtg
    11161 tttttgagga acgaaaaaca atttcttttc cgtaagactt atgccgattt ttttctacaa
    11221 atcgttccgt ttgtatataa gggatttttt cgtcagcttg tccatgccaa aagaacagag
    11281 gacgtccagc taacttttcc ggctgcaatg acaaatcata gctcttaacc catgaaatca
    11341 aatcaaaata gtcttttggt acgacataat tatattccga tgcgcgcctt acgatttctt
    11401 ttccatattc caaaggtgca ggggaaccca tcaaacacac gcccgctact atatgaggat
    11461 gtttagccaa caaggcgcat gttgtcattc cccccatcga aaccccgcca actgcaagct
    11521 gatcatgtag aagacctctt ttttctaaat gcttgataag tgtgtcaaat tcaaacagat
    11581 ttccgtagat actatcccaa aatgtatagg atggaataga agaaaccggc tgtttgcgct
    11641 ccccatgatt catcgcatct ggcaggatca cacgaatgcc ctgctgcgca atttttcttc
    11701 cttgcgtcaa aactaactcc ttacttgtct gccatccgtg ataatagatg acaacgggaa
    11761 tacgttcctc tcttaattct ttcagaacaa cttctaacac tggaatatga tggacagaac
    11821 gtttcaatat aattggattc aattgttact cacctatttt cattaaattt cctgatcgcc
    11881 atagcaacca tgctccaaca gttgtctgga acaggttcag tgtaccaaat aatataaatg
    11941 caggactgaa tggctcggga aataagcaca gagaacaaag tcccaccact cctaatgcta
    12001 gcgaaaggag tggataaata gaaaaattca aaaaactggc aacgctaccg aaaatattac
    12061 caataaacag tatcaaaaag aaaaaaacgc ttaaaattaa accatctgtc agcgacatct
    12121 gaaaaacaat gttctctacc tcaattggct gttgaatcga atagacacct aagtatatac
    12181 tgagaaggag acttagcacg tggctggcac aaaacacacg attgaccgtt ttcattttaa
    12241 tcacctaacc tatctttata attctattat aatcatttta tcattttttt gtatgtataa
    12301 agtttcaatt tttcttcact tacgattttt tttgatattg ttgttatata aatgaaagga
    12361 gttttacaaa tgattgatcc aaaaatgttg gggatgatct tcctcattaa ttttgcttat
    12421 atcactctga acacgttacg tttcatgttg acaatgaaag gctatcgact gattgctcca
    12481 cttgtcagta tggtcgagat cacgatttat atcgtcggct tatcccttgt tttagatcgt
    12541 ttagataatc cactgaattt atttgtctat gcgttaggtt acgcagtagg tatcagtgtc
    12601 ggaattttga ttgaagacaa attggcatta ggatacatca tggtcacaac gattttgcca
    12661 gcaaatagcg cagaagataa aagtttgccg ggtatactga gagaacacgg ttatggtgtg
    12721 acacagactt ctgcaatggg gctggaaggt gagcggctag ttctcgaaat actttctcct
    12781 agaaaaagcg aacgtgaact gtatcgcctg atcaaagaaa tcgaagagcg tgcttttatc
    12841 atttcttatg agccaaaata tatttcaggt ggtttctgga ctaaaaaagt gagaaaacga
    12901 caaggaaaat aactcacaaa cttaaaaact gtctaatatc taaattaaat tttaaatgtt
    12961 agacagtttt tatttattat tttgattaaa aaacatcgac atatactcat caatttgtta
    13021 ttatacttta tatacttatc aatttaattt ggagatatta tggaaattca acgtagaacc
    13081 actaattttt tacatttagg ctcttttttt gcaactttga cgatcttatt ttttctatgt
    13141 tattcatacc ttaagacctc acatgcgcct tctagtgcat taggctggtt gcttttggat
    13201 cattctgata tcacagaagc cgaagaaaat ccgttttttt tgattttgtc ttctctttgc
    13261 ggcttactgt tttctgttta tttcggtgcc tatttttttc atcgacatcc tggtacgtta
    13321 aacgaagctt caagcgtatt gattgcattt aaaacgtttt cttttttagc aattcttttt
    13381 tattcgttta atcacaatac gcttttcttc tttatcatga atggtttagt cgtgatttta
    13441 tccattttta cttattttat tttttcactc atttttagcc aattgaaatg tccgctcttc
    13501 tttcgattag ttcctgtcac ctgttttatt tacagcttgt tttccttttt tgtccttgct
    13561 ttaatgccac tgaccaaccc ttcgacgatc caagtcgcag gaaatctgtt ggatatgctc
    13621 ttcatcgtca gtctaggtgt atttatgtgg caaagaaaaa acaaacaaaa taaaaagcat
    13681 tttgaagcct gactattacg acttcataaa tgctttttta gttttaaaca cttcaatcta
    13741 aaagaataac ccaagattgg ataaattatt aatgactcgc cattcgtttc ttagtgattc
    13801 tggattatca aatggacttc ctaatctaat cagctagttc ttcccataaa atgccatact
    13861 tgactgaatc ataatattga ttatttaaaa atctaacttt tcttatcact acttcctttg
    13921 tcattccaca tttctcacca tttttttgca ttcctttgtt tccagaccat gtagtgaatc
    13981 taataggtgg tagataggca aaatactcaa ataattcttt taaccataaa ggaagagaaa
    14041 ggctcctcct gcaagagtca gtataatttt tgcttactgc tctcttaggt tttactcact
    14101 aaaactgttc catattcttt gatataagaa aatgcatgcg gtataaattt cttgctcagc
    14161 tcagaaaaga tttgtcgttt aagaaaggcc atttcctcca ttgtcaatga aggatccaat
    14221 gttggtaatt caatctcaaa attgtttttt tcgacaatag gtaattctaa tgtgaatgat
    14281 tcttcttcct ttatagtatt cgtcacaagt agagactgat ggaaaatact aggccggcga
    14341 tttttatatt tattcttacg tatcctgtca acgataactt ctatttgatc aaaaaagtac
    14401 gattcattta cgtctccaat aagttcggct aattctttga atgccttcgt tacaggaagc
    14461 tgattcttct gtacaaaaaa gtaattagcc aaagtaagcg ggaagtgttc tatagaggaa
    14521 agtgtgataa aacggtactt ctcatttcct gcagttgtcc tcagcaattc tgtctctcgg
    14581 ctgtttctta ctccataaaa atacgcttct ttccgttcat cttcgaaaca atacgcccaa
    14641 ataacttctc ccatcgctaa tttttgttca tcaacagaga gtctcttcaa ttgttcagct
    14701 atggtttcag cagccgaagt ggcttgttgc aagtaatctt taggatcaaa tattggaaag
    14761 ttcaaatgat atcttcgttc ttccctcttg attaatcctg catcgatcaa taaatcaaga
    14821 aaatgggaaa atttattttg cgaaaattct tttttcaatt ctcttagaat cgtttcttgt
    14881 tctcgatgtt catatagata atcggtcaat gaagaaaaaa gcggatcatc ggtcagtttt
    14941 tgataaaagt tttccttatt ttttgaataa tagttcatat atgttctctt ttctatccgt
    15001 tttattttac ttaaaaggct tttacgtaaa aaggaggaag aacaagagtc ataattgact
    15061 gttattctcc tccatttctt cggcctttag tatgttctat gtttcttttt atatcaatcg
    15121 cttatccatt cattttgaat gcttcatact accatttgat tagctaaata cagccgtcaa
    15181 ttgaggtacg acttgttttt tacgtgaaac gacaccttta agcaaagcac ggttgttggt
    15241 caaagttgtt tggaaagctt cttctacttt ttcttttcct ttaccagcaa caagtaattc
    15301 tgaatcactg tctaagatgt ttgtgacaac taatacgaac agatcgtagc catttgcttt
    15361 catttcatct tccattgctg cttctagctc tgcttgtcga tccatcactt cattaaggtc
    15421 cactgtattg acttgagcga tacgaacgtt ggaactgccc attgggaaac tttttgcatc
    15481 caaatcaaga agaaccgcag ctgatttatc acttagattt gttcctgctt tcaacatttc
    15541 aagtccataa gtgtttagat cgacttcagc gattgctgca agttcttttg cagctgcttc
    15601 atcttcaggc gtacatgttg gtgatttgaa caacaatgta tctgaaatga tagctgagag
    15661 catgattcct gcgatttctt taggaattgt tacttggttt tctttatata gttttaaaat
    15721 aatcgtactt gtacatccaa ctggttctgc acgatagtac aatggattag ctgtttcaaa
    15781 gtttgcaata cgatggtggt ctactacagc taaaatattt acttcgctga tatctgaaat
    15841 actttgttgg aattcattat gatccacaag catgacatct gcattttctg ctttagctga
    15901 ctctactact cgtggtgcag atagctgaaa gtggtctaat gcgtattgtg tttcttcatt
    15961 aggtgtacct agagcaactg cttctgtttc tttacctaat tcattttgca agtgtgaaaa
    16021 cgcaatggct gccccgattg catctgtatc tggattttgg tgaccaaaaa ctaaaatttt
    16081 tgacatgtca ttcgctcctt tgtgatttct cctatttaat aatagcaaaa aaacggaaag
    16141 aagcaatact tatcttcttt ccgatgcgac ctatcgcgtt aaatattttg tatactcttc
    16201 tgtatgaagc aatcgtttag cattttcgac acgttctttt gtaggtggtt cgatcccttc
    16261 taatggatat ttcaaaccaa gtgtttccca cttgtatttt cccatcgtat gataaggaag
    16321 aatctctact ctgtctacat ttgacaaggt ttgaataaag ttgtctagtc ggatcaaata
    16381 ttcatcataa tcacttcgct caggaactag tacatggcga atccaaaccg gtttgttgat
    16441 ttttgacaaa tattgagcca tttctaaaat attttcattg tcccaatgcg ttagtttttt
    16501 atgctcttca ttatcgatgt gtttgatgtc aaataacagt aaatctgtat acttcatcaa
    16561 ttcttgaaaa cgtgaaaaga aaggttcttc atacgtaaaa ggttttccgc atgtatccaa
    16621 tgtagtatgc atcttccgct cttttgcttt tttaaatagt tcgatcaaaa aatcgatctg
    16681 caatagaggt tctccaccac taacagtaat accaccttta tctccccagt aaggtctgaa
    16741 gcgttctgct ttatctaaaa gttcatctgc tgtgtattct ttccctccgc caatattcca
    16801 agtatctgga ttgtgacaaa attggcaacg catgcggcat ccttgcataa acacgacaaa
    16861 gcgcagtcca ggtccgtcta ctgaaccgaa agtttcgata gaatgaacat agccgattgt
    16921 tttttcttcc atttaagttc acatcttttc tttgatttca ttttaagtac aagttagctg
    16981 tcgaagcgaa gctttctgaa caaaattttt cgcaattgcc gcttcgttat gtgtaaaatt
    17041 tacagggacg gaacatacaa gtcctgcccc tgtaaatcgt ttctttcaaa taagcatact
    17101 gattattcga ttttgatgcg atggctattc aacgtccttt cgacgctaag tcgaaaaact
    17161 tttttcacga actttttaca ttctgtcgtg tgaagttctc atcaagacat ctaattgttg
    17221 ttctcttgtc aagtcacgga atttaactgc ataaccagat acccggatcg tcaagttcgg
    17281 atatttcatt ggattttcca ttgcatcacg caataaatca ttactgaata cattgacatt
    17341 caaatgataa gctccttttg agaagtatcc atctaagaca ttacgcaagt tttcgattct
    17401 tgtatcttgt tcttttccaa gacctgaagg attgattgtt tgggtatttg aaattccatc
    17461 caatgcacag ccgtaattca ttttagctgt tgagttcagg ctagctaata acccactttg
    17521 ttccgcattg taacttggat ttgctcctgg cgcaagtggt tttccagctt cacggccatc
    17581 aggagtattt cctgtatttt taccgtaaac aacatttgaa gtaatcgtca ataatgaagt
    17641 tgttggtttt gagttgcggt aagttttatg acgtttgatt tgtcccatga agtattccaa
    17701 gatccatgaa actaattcat ctgcacggtc atcatcattt ccgtatttag ggaagtcgcc
    17761 atccacttca aaatcaactg ctattccttt ttcattacgg attgctttta cttttgcata
    17821 tttgatcgct gacaagctgt ctgccgcatg agagatccca gcaatacctg tagcaaatgt
    17881 gcgttgcaag tcagaatcca tcaaagccag ctgagctgct tcataagaat atttatcatg
    17941 catataatga atgatgttca acgtattgac atatagttct gctaaccaat ccatcatatt
    18001 catgaagtta tgtttcactt cttcaaagtc tagtatttct gatgtgattg gacgatattc
    18061 tggtccaact tgggcgccag tcacttcatc gactccgcca ttgatggcat ataatagtgt
    18121 tttagccaag ttagcacgag cgccaaagaa ttgcatgtct tttccgacaa ctgttcctga
    18181 tacacagcaa gcaatcgcac aatcatcaga accccattgt tcacgaagct gattatcatt
    18241 ttcgaattga atcgaagaac tttcgatagc gattctgcta gcatatgttc tgaatccttc
    18301 tggaaggtgt tcagaataca aaacagtcaa gtttggttct ggtgaaggtc ccatatttgt
    18361 taatgtatga agcagacgga aatcattctt tgtaactaat gaacgaccat ctaatcccat
    18421 acctgcaatg gataaagtag cccagatagg gaatcctgag aataattggt tatattcagg
    18481 tgtacgcgcg aatttgacca tacgtaattt cattactaag tggtcgatca attcttgtgc
    18541 ttctttttct gtgattactc cattatccaa atcacgttgg atatagatat caaggaatgc
    18601 tgagatacgt ccgattgaca tcgcagcacc attttgtgat ttgattgctg ctaaatatcc
    18661 gaagtatagc cattggacag cttcttttgc atttgcagct ggtttagaaa tatcatagcc
    18721 atatttcgca gccatttctt tcatttgcgc taatgcacga tattgttcag tgatttcttc
    18781 acgtaaacga atcacttctt cactcattgt atgataacca gtcatatcat gatctttttt
    18841 cttttgttcc atcaaatagt cgattccata caatgccaca cgacgatagt caccgatgat
    18901 acgtccgcga ccgtaagcgt ctggaagccc tgtaatgatt ttgtttttac gagcagcacg
    18961 catttcagca gtataagcgt caaatacacc ttgattatgt gttttgcgcc agtcagtgaa
    19021 aatatgtgtc aattcatcgt ttggtgtata gccattgctt tttagcgcat tgttagccat
    19081 attgattccg ccgaacggca tgaatgcttg tttcaaaggt ttgtctgtct gtagaccgac
    19141 gattttttcc aaatctttat ccaaatagcc tgcatcgtgt gaagtaatag ttgatacgat
    19201 ttctgtgtcc atatcataga caccgttacg ctcgaattgg atatcattta acttttgcaa
    19261 ttcatcccat aatttttctg ttgcttctgt tgggccttcc aaaaagctgt catcaccgcg
    19321 atattcagtg tagttatttt gaataaagtc tctagtgtct acgccttctt tccatttggt
    19381 acctttaaat ccattccatt gctccattgt atggacctcc taaatttctg ttttatgtaa
    19441 cagtttttac gtgattagta taacacagca ccctatcttt gcaagggttt tcttgttttt
    19501 tatttaacaa tttttatgtt ttatttacat atatttaaat caacgttgac ataccaacat
    19561 ttaagcattg tgaacacttt catctttttt tgcaaacgta taaggattta ttaaaaatga
    19621 atgaaaaaga gacgccgcct gtattaatac agatggcgtc tcttcattaa aatactacaa
    19681 cagttacgac tcgatgaaaa tctcaggagc atcgataact tcgatgactt ctccaccttt
    19741 tttctcatcc atcgcaaatg atccattcga tgttcgatca cctataggga aatcagttgg
    19801 gtcaatcgtt aactgctgcc ctttttgatt catcaaggtt atttcttttg atcttccttc
    19861 cgacatatag ataatacggt gcggattttt tttcagctca cgcatgaccg tcactccccg
    19921 cttcgcacgt gaagtttggc tgatttcttg agcaagcatg cgtttaacag ctcctcgctg
    19981 agtaacgatt acgatcggcg tatcaccttc tgctaacaca agcagcccgt tgataatcct
    20041 atctccatct ttcaaattca tagacttcac tccagctgcc tttgctccaa caacgggaac
    20101 atctgttaaa ggatagcgca aacccattcc ttgatgcgtt actaagaaaa catctaagcc
    20161 tggctgatct tctttcagat acacagcaat cagttcatct tcttccgcct ttagcttcat
    20221 acagctgagc ggacggctct tataggtgcg ccatggttcg aactctgtca ttcgtgtttg
    20281 cttgatcaat ccattcttgc tgatgaatac aaatgttttc tctgcttgaa ttttttgata
    20341 tgggaaaaca gctaaaatcg attcgtctac agacagattg gagattgttt gagaaatgtg
    20401 ctcaccagca tctttccatt tcaaatcggg tagttcatgg acagggcggt agatcacatt
    20461 tgctttattt gtgatcagaa gaacatggtc caatgtactc aattcacctg agtatagcaa
    20521 gtagtcgcct tctcgcatcc cgatttcttc tggtttggaa gcactataag aacgaaggct
    20581 tgttcgcttc acatagcctt ctcgcgtcac actgacaatt acgtcttctt gtgccactaa
    20641 gacttgcgta tcaattttga tttcttcgat ttcgtcttcg attgtcgtta gacgagcgga
    20701 agaataattt tttttcactt ctcgcaattc ttttttcata acagagaaaa gctctttgtc
    20761 atttgaaagg attttattca actctgtgat ttgcgcaatc aagctttcgg attccttttg
    20821 aagctctgtg atatccgtgt tcgtcaaacg gtataattgc aatgtgacaa ttgcttctgc
    20881 ttgttcttct gtaaattgaa agacgtcgac taaattcttt ttggcgtctt ttttgtcttt
    20941 actttcacga atcgttgcga ttacttcatc cagaatcgat aaagctttca tcaatccttc
    21001 tacgatatgc tgtctttttt gagctttggc taaatcgaat tgactacgtt ttgttatgac
    21061 ttgctttcga tgctcgatat aacttcttaa aatgtctttc agtccaactt gatgcggagt
    21121 catatggtcg atagcgacca tattgaaatt gtaattgatc tgtagctcag tgtttttgaa
    21181 caaataattc aaaattcctt gagcattggc gtcttttttc aattcgacga caatttgcag
    21241 acctgttcta tcactttcat ctcgtacttc agctattcca tcgattttct tattcaaacg
    21301 gatctcatcc atttttttca ccaaggtcgc tttatttact tcatatggga tttctgtgat
    21361 cacgatttgc tgtttattac ccttcattgc ctctatcttt gttttcgaac gaagaataac
    21421 ttttcctcgt cctgtttcat aagctttttt gatttcatct tttccttgca agatccctcc
    21481 tgttggaaag tcaggtccag gaatatattc catcaatttt tcaaggctcg cttgtggatg
    21541 atcgatcata tagattgtgc catcgatcac ttcagctaag ttatgagtcg ggatttctgt
    21601 tgcatatcca gcagatatac ctgtcgatcc attgacgaga aggtttgggt atcgagctgg
    21661 aaggactgtt ggttcttttt ctgtatcatc aaaattccac acgagatcga ctgtttcttt
    21721 ctcgatatct gctagcatct ctccacttaa cttggataat ctggcttcag tataacgcat
    21781 cgcagcaggt ggatcaccgt ccatactccc gttattcccg tgcatttcga tcagtacttc
    21841 ccgcaacttc cagtcttggc tcatgcggac catcgcttca taaatactga tgtcaccatg
    21901 aggatgataa ttccccatga tatttccgac agattttgct gatttacgga atcctttgtc
    21961 atacgtattg ccatctttgt tcatggcaaa taatatccgg cgttgcactg gcttcaatcc
    22021 atcacggata tcaggcagtg cacgttcttg gataatatat ttggaataac gtccgaagcg
    22081 gtcacccatc acttcttcta aagttaattc ttgtacttct tgtcgatttt ccatcaggtg
    22141 acctcctatt ctacttcaaa taactgattg ttttcatttt tatctgctcg ttcttcatct
    22201 aataaatcat tagaaactga aggagagatt tcagtatcct cttttttatc taagatactg
    22261 ccatcttctt cgagcgtaaa ttgcacgtga ttttcgatcc attttcttcg aggttctact
    22321 ttgtcaccca tcagtgtggt tactcgacgt tcagcttgcg cagcatcatc gatacggacg
    22381 cggatcaacg tacgggaagt cggatccatc gttgtttccc acaattgttc cgcattcatc
    22441 tctccaagtc ctttatatcg ctgcagcata tatcctttgc cgactttttt aatcattgct
    22501 gccaattcgt catctgtcca cgcatattca atgacttgct tctttccttg tcctttggat
    22561 actttatata aaggcggtaa cgcgatatat actttcccag cttcaatcag cggtttcata
    22621 taacgataaa agaaagtaag cagtaatact tgaatatggg cgccgtctgt atccgcatcg
    22681 gtcatgatga ttactttgtc gtaattacag tcttcgatag aaaactcagg accgactcct
    22741 gcaccaatcg tatagatcat cgtattgatt tcttcatttt tcaagatatc ttgcatttta
    22801 gctttttcgg tattgatgac ttttcctcgt aaaggtagaa ttgcttggaa ctttctgtct
    22861 cttccttgtt tagcagatcc gccagcagaa tccccttcga ctaaatacaa ttcatttttc
    22921 ttagggtttc gggattgtgc gggtgtcaat tttcctgaaa gaagagattc gcctttttta
    22981 cgcttcttcc catttcggct ttcttctctg gctttacgtg ctgcttctct cgcttctctg
    23041 gctttgattg ctttacggac caacatctgg ctcatttcgc tattttcctg caaataaaag
    23101 cccatttgtt cactgatgac gttatctact acggtacgag caactggcgt accaagtttt
    23161 tcttttgttt gcccttcaaa ttgcagaaga ttttcaggta cacggataga aagtacagca
    23221 gctaaccctt ctctgaaatc actaccttcc agattcttgt cccgttcttt cagcaaacca
    23281 acttttctcg catattcatt ataagatttc gtcatcgccg ctttcatacc agcttcatgg
    23341 gttcccccat cttttgtccg aacgttattg acaaaagata aaacattttc tgaataaccg
    23401 tcattgtatt gataagcgac ctctacttcg ataccttctt tttctcctga aaaataaaca
    23461 actggtgtca atgtatcttt ttcttcattc agataatcaa caaattcttt gattccttct
    23521 tcgtaatgaa aaatttcctt gactggttct tctccacgaa gatcagaaag agagatttta
    23581 acgcctttta gaagaaaggc agattctctt aaccgttcgg ctaaaatttc atatgaaaat
    23641 ttcgttgtac tgaatattgt atcatctggt aaaaaatgga cagtcgtccc gtttgctttt
    23701 tttgtttttc ctatcttttt caaagtaccg tcaggtttac cgccgttttt aaatttctgc
    23761 tgatactcta cgccatctct aacgatcgtt acaattagcc atttcgataa ggcatttacc
    23821 acactggctc ctacaccgtg cagtccacca gaagttttgt accctccttg accaaacttt
    23881 ccgccagcat gcagcacagt aaaaatcact tcaactgttg gtattccgga agcatgcatt
    23941 cctacaggca tcccacgtcc gctatctgca acagttatac tattgtcttc atggatggtc
    24001 acatcaatct cactgccata acctgataat gcttcgtcaa ctgcattatc gacgatttca
    24061 tagactaaat gatgcaagcc tcggctgtca gtggatccaa tgtacatccc tggtcttttt
    24121 ctaactgcct ctaatccttc caatacttgg atggacgagt cattgtattc gttgtttact
    24181 ttttttgcca aggcaaacgc tccttcaata atactttgcg gcaaaaccgc accacgatta
    24241 tcatactaga aaaggtcgtg aaaaaaaaga gggtagacga gaaatcaatt ttaattatct
    24301 cctaaccgct ttttcgacat tcccctctat cgatcatctc ttctttgtgg tcatttttat
    24361 ttttggtttt ctttcaactt accaagttca atcttaatac aacgatccat tacgatatct
    24421 gtacgtcctg cttttcttag catctcagct gcttctttgt tttcaatccc taattgtgcc
    24481 cagaacactt tagcatcagt tttcaaaaaa tcacctgcta tttcaggtaa aaattcactc
    24541 cgtctaaata catctacgat atcgattgga tcatcgattt ctgtcaaatt cgcatagact
    24601 ttctcgccta gaatttcttc accagccaat aatggattta ctggtatgat tttatatcca
    24661 ttgtcttgca atacctgtgc aaccatgtaa cttgttcgtt ctggtttatt gctcaagcct
    24721 acgacggcaa tattttttgc ttcttccaaa tagttgaaaa tcgtttcttg tgttggattt
    24781 tttacagaca tttctgccac cccttgcttt tctttttatt ccatctatta tacttgtatc
    24841 tttcattttt tcaattgttc ctgttaccta ttcatgctaa aataaaggat agttttcaac
    24901 ttgaaagagg gtaaaaaatg aaattgatct tattacttat tttagcatat cttttaggtt
    24961 ctattccttc cggtgtctgg attggcaaat tgtttttcaa aaaagatatc cgacaacacg
    25021 ggagcggtaa tactggaacg accaatacat ttcgtgtatt aggcaaaaca gccgggattg
    25081 ttgtcctgct tatggatatt ttaaaaggta cattggctac ttgtttgccg atgatcttcc
    25141 acctttctgg gattaaccct ctttggtttg gggtatgcgc cattcttggc catacatttc
    25201 cgatttttgc tgggttcaaa ggaggaaaag ctgttgcgac aagtgcagga atgcttttag
    25261 gatttaatcc tgtatttttt gtttattctt gtatcatctt tatcgttagt ttattttgta
    25321 caagtatggt gagtttgagc agtatgatca gtgcagtatt gatcacttta tctacgatcg
    25381 tccttcctta tgtagctcct gtgattttgg ctaagcccaa ttggttactg acgatcattg
    25441 cctttttagt ttcttccttt atcttttatc ggcataaaga caatatcaag cgtatcagaa
    25501 accatactga aagtcgaatc ccgtttggtt tgaatagcag caagaaaaaa tcctgatact
    25561 ttttcattcc aaagagataa aacgggagtg tgacaaatcg atgtcacact cccttattac
    25621 ttacaggata gcttttttac acaccttggt aaacggtgtt ccctgctaac ttctcggtca
    25681 caacctctta cttcactgtg atggaatatt ttgtcttgaa gatttcatgg gcacctagtt
    25741 gattgatccc tactttttcc atcaagtttc cactactgtt caccgtgtca gcgattccgc
    25801 accacggttc gatacaaacg aaaggcgctt cttttggata aggagaccag atccctacat
    25861 aaggcatatc tttatagctt aaagttacgc tatgggaaga tttttcactt cgaatggcgt
    25921 acgcatttag accccttgtt tcaaaaacca aggcatcttg ctcaaaaagt tcacgattca
    25981 aagccagatt cgtatttgtc tgacctaacg tcttttgatc catatcgatg aatgggcctt
    26041 tcaatggtag gcgtaatctt gatttcaatg gagaaaatgc cagatagaaa tcttcaaatg
    26101 acaatccttc ttcaagaggt acattgaaag caggatgtcc accgatagaa aagaacattt
    26161 ctttttcacc ggtatttgcc acttgataat gaaccgtgat gccgtctcct cctaattcat
    26221 agctgatcac taattcaaaa tcaaatggat acttttctaa tgtctccggc gtactcctta
    26281 agatgaaact agccatttct tgtccatgtt caatgacttc aaaatccata tcccgagcaa
    26341 atccgtgttg ccccatttga tatgttttcc cttgataaac atactgatca tcttttaaac
    26401 gtccaacaaa agggaataaa accggtgcat gtctgcccca atacgctgga tcaccttgcc
    26461 agatatactc taaaccatgt tcttttgatt tcagactgat caattccgca ccgtgttcag
    26521 cgatttcggc gatcagctgg tcattttgaa taataacagt cattgccatt cctccaactt
    26581 cgacttactt tttaaaatgg gaaggctgga acaaacattt ctatctgccc cagtcccctt
    26641 acttctaata actgtgtttt gctaactcgt ctttaaaacg ggaattcaat acttttaaat
    26701 aagttccctt catgcctaac gaacgagatt caatgattcc agctgattcc aattttcgta
    26761 aagcattgac gatcacagaa cgagtgatgc cgatactatc ggcaatatta gaagcagtca
    26821 gacgaccttc atctccatcc aatgcttcaa agatagcttg tacagccttc aattcgctat
    26881 aagataatgt gttgattgcc atttggacag ccgttgcact ccgtacatct gcttcgatgc
    26941 ttcgagactt ctgataaagg atctgcatac cgacaaccgt agctccatat tctgctaaga
    27001 ctagatcgtc atctgcaaac gattgttcca tacgagataa gataatcgta cccaaacgtt
    27061 cgccagctcc aaagatcgga acgacagtcg tcagaccaaa tggatatttc tctcttgact
    27121 ctaccggaaa tgcagtaata tcactagtaa ttgggatatt agcttcagtt ttcatcaact
    27181 gtgccactgt atcagtataa gattcaggaa attgtttctc aacaaacatt gttttgattc
    27241 gttcattgtt cacatcgtga cgttcattat aacctagtaa tactccgtca cttcctatga
    27301 tataggtgtt gctgtcaaga ataccaccta gtgtgacagc cattttatcg taaggcaaat
    27361 ctgcttgcat gtcaaaagta ttcttttgct gcaaaagtgt gtttatcttg cgggttttcg
    27421 ttagcaagtc tgtcattgtc gtcctccgat tttttataaa atatagcgac ttaaatcttc
    27481 atttgccgca attgagccaa gtttgtcatc cacatatgct tctgtgatcg ttatttctcc
    27541 catttgcata tctggtgctt caaataatag atcttctagt agtttttcca aaatggtatg
    27601 cagtctgcgt gcgccgatat tatctgtgtc acggttgaca tcgaaagcga tttgagcgat
    27661 ccgttcaatt gcttcttttg taaacgtaac tgacacattt tctgtaccga tcaacgcgac
    27721 gtattgtttt actaaagcat tatttggttc ggtcagaatc ttcacaaaat cttcagctgt
    27781 caaatcatct aattctaccc gtatcgggaa gcgtccttga agttctggaa ttagatcact
    27841 tggtttagac aaatggaaag ctcctgaagc aatgaatagg acgtgatctg tttggatgat
    27901 cccgtatttt gtgtttactt gtgaaccttc gacaattggc aatatgtctc tttggacgcc
    27961 ttctctggat acttctccag attgctgtga tttagaagtg atcttatcga tttcatcgat
    28021 aaaaataatt ccactttctt ccgctaattt gattgcctca ctatggatat cagcatcctt
    28081 gactaatttt gctgattctt ccttgatcaa taactctaaa gcttctttga ctgttaccgt
    28141 ccgttccact tttttcttcg gtgtcaaagc acctagagtt tcatttaggt cgatccccat
    28201 ttgctccaat ccattgttca tcattggtgc aggtttcttt tggtcttcaa cttcaatggt
    28261 tacttcacga ctatccagta aacccttttg tagttgttcc aagactgtac ggcgattgat
    28321 tcgaatatct tctgtcactt cttcttgcgg ttcagcggta ttttgctgac tagcattaaa
    28381 aagattcatc atttgttcaa attgattagt ggattgtttc tgttcttttt tgataccagg
    28441 taccaagatt tttaccaaac gtttttctgc atttttttta gcacttgtgt atacacggct
    28501 gtactgctct ttttctacga tttggatcgc attttctact aaatcccgaa ccattgattc
    28561 tacatctctt ccgacataac cgacttcagt aaattttgtt gcttcgactt tgacaaatgg
    28621 tgcattgacg atttttgcca aacgtcgtgc gatttctgtt ttaccgaccc ctgtaggtcc
    28681 gatcatcagc atattttttg gtgtaatatc ttgttgcatt ttttcatcta actgcaaacg
    28741 gcgatagcgg ttacgcaaag caacggcaac agattttttt gctgcgtgct gtcctacgat
    28801 atattcatct aattcactta cgatttgtct tggtgtttgt tttaattcat acatatctac
    28861 tcacctctta cagttcttct acgataatat tatgattagt aaagatacag atatctgcgg
    28921 caatatttaa cgcattttct gcaatttctt tcgcactcat gtcgttttga gcatagtttt
    28981 tcattgctcg ggctgcagcc aacgcaaaat tccctcctga tccgatagct aagataccat
    29041 catctggtgt gataacttct cctgtacctg aaacaagaag catttcttta tcattcatta
    29101 cgatcagcat cgcttcaagt ttttgcatag attgctgtgt ccgccattct tgagctaatt
    29161 cgacagctgc gcgttgtaga ttcccgttat attcgtttag tttgccttca aatttttctt
    29221 ctaaagtaaa cgcatctgca acacttccgg cgaaacctac aacaacttct ccattgtaga
    29281 tacgtcgtac tttctttgca gtgcctttca tgacaacaga ttcacccatt gttacttggc
    29341 catctccagc catagcaaat ttcccgtctt tttcgacggc acagatagtg gttgaatgaa
    29401 atggtgattc gaccatgttt gtttcctcct aaatttgttc ttttccttat ttttacgctc
    29461 ttggatggaa agaacgatag tttttttgta aactttcttt tgttacatgg gcatagatct
    29521 gggtagtcga taaattggca tgtcctagca attcttggac tgtccgcaaa tctgccccat
    29581 tatttaataa atgagtagca aatgtatggc gcagcatgtg aggatggata tcactatcca
    29641 aactgctttt tttgatcatt tgattcaaga catattcaat tccagtaggc gtgattggtt
    29701 ttccatgatg attcacaaaa acgatatcat gctcttcgtg atattttgtc atcaatacct
    29761 ggcggccttc cctgaaatat tcttgcagag catcttgagc aaaagaacct agaggagcat
    29821 atctctcttt gttcccttta ccatggatca acatgacctc tgaatcaaaa tcaatgtctg
    29881 ataccgacaa actgctacac tcacttaaac ggatgcctga cccgtaaagg acttccagta
    29941 aagcgcggtt cctcaaatcc aaaggactat ctcctgctac gctgtcaaaa agtgcttgca
    30001 tttcattttc ataaaaaaaa cgtggcagtc tcaaattttt ctttttgaga tgaacgtaag
    30061 aaaatggatt ttcttttatc acttcttctt tgagaagata ctgataaaac gaacgtaggc
    30121 tggctatctt gcgactgata gaatttctgc tatagctagg acgatgatca gctaatgcac
    30181 tcaaatagac acgaaccgta aaatattccg ccttcagcag atcagcgtct ccagattcct
    30241 ccaaaaaatg tttgaaatgg agaatgtctt cttcatatgc ttctttcgtt ttttctgaat
    30301 atcctctttc gacaatcaaa taacgcaaaa atttttgttc ccacgtggct tctgtcattt
    30361 tctcaccttc cttttgtccc agagaataat ttagcacagc gtttataaaa agacaaataa
    30421 attgtcagaa tttaaccaat atttctaagt ttgttcacaa ttggcgcaat tcctcacatt
    30481 ttgtttgaga aattcttaag aaaaacgcaa gaaaaagagc gagactatcc gtctcaccct
    30541 cttcatggag tttccttact catttgggat tgcagttttt tctaattctg tttttattgc
    30601 ctcattagct tttaaagctc gttgtgcaat tgcttcatat cttgcttttt tgtctcgaat
    30661 gcgctctggc agttcaggaa acagaccata gttggcattc atcggttgga aatgttttcc
    30721 ttccgcatga gtaatgtagt aagccatact tccaatagct gtttcttgtg gaaactcgac
    30781 tggttccatt tcttttgcta agcgtgcggc gttgattcca gcaagtagtc cgctcgctgc
    30841 actttcaaca tagccttcta caccagtcat ctgacctgca aagaacagat cttcgcgttt
    30901 cgttgattgg taagtcggtt tcagcaattc tggcgaattc ataaagctgt ttcggtgcat
    30961 cacaccatag cgaacgaatt cagcattttc taacccagga atcatccgga aaacacgttt
    31021 ttgctcgccc catttcaagt gagtctgaaa gcccacgatg ttgtataaag aagctgcagc
    31081 attgtcttga cgcagctgga taacagcata aggacgtttg ccagttttag gatcttccaa
    31141 tccaactggt ttcataggtc cgaaaagcat cgttttgaat cctcgctgtg ccattacttc
    31201 aattggcata catccttcaa aatatttttc tttctcaaaa gatttaagtt ctgccacttc
    31261 ggcattgatt agtgcctcat ggaaagcttt gaattcctct tctgtcatcg gacagttcaa
    31321 gtaagctgct tctcctttgt catagcggga cttcaaatat actttatcca tatcgatcgt
    31381 agctttgtct acgattggtg cagctgcatc atagaaataa aaaccatctg aaccattgaa
    31441 tgctttgatg ctttctgcta atggatgaga agtcaaaggt cctgttgcta ctacggtgat
    31501 tccttccggt atttcagtaa tttcttcgtt tatcactgtt actaatggat gctctttgac
    31561 ttttcgggta attgtttcag aaaaagaatc gcggtcaaca gctaaggcac caccagctgg
    31621 cactgctgtt tcatctgccg aagtgattac taccgaattc aatcggcgca tttcttcttt
    31681 caataaccct actgcattag ccaaactgtt tcctcttaat gaattggaac atactagttc
    31741 agcaaaatta cttgtgtgat gcgcctcagt cgatttgact ggacgcattt catataaacg
    31801 gacagggact cctgcttgtg cgatctgcca agcagcttca cttccggcaa gccctgctcc
    31861 aacaacattt accattttca atgaaagaac ctcttttcta ttatttttgg atgtcttctt
    31921 cgtaatctcc atttacacag actacttgtt taccgccttt gactttcttc tcgaccagat
    31981 atccgtcaca ttttggacaa tttctgccca ctggtttatc ccaagaagtg aattcacatt
    32041 ctgggaaacg ggaacaacca tagaatagtc tgtttttctt agattttcgt tcaatgactt
    32101 gtccttcatg acatactggg caagtcacac cgatttcttt tacgattggt ttcgtattcc
    32161 gacaatcagg aaaattactg caagcataaa acttcccata tttccctaat tttatcacca
    32221 tcggatgtcc acagacatca caatcgaatc ctgctggttc atctttgatt tgaatttttt
    32281 cgattttttc ttccgcattc gtcagttctt tttcaaacgg tttatagaaa cgatcaacca
    32341 ctttgaccca cgcttccgtg ccttcttcaa ttttatccaa atctccttcc atttctgctg
    32401 tgaaatggat atcgacgatt tgagggaaga attcacagat taatgaattg acaatttctc
    32461 ctagttcagt cggctcaaat cttttttgtg tcaattttac atagtagcgt ctttggatcg
    32521 tatcaagtgt tggtgcataa gtggaaggtc gccctacccc gttttcttct agtgcacgaa
    32581 tcaacgtagc ctcactaaaa cgtgctggtg gttgagtaaa atgttgtttt ggttcaatat
    32641 caacagattg gactacatcg ccttcttcaa gttctggaag aatattttct ttctcttctt
    32701 tgccgtcatc tctaccttcc acatacactt gcatgaatcc tttgaatttg atttttgaac
    32761 cgttcgcaat gaagatgaca ccattttgtt ctaatgtcac tttcattgta tctaaaatag
    32821 ctggtgtcat ctgactagcc acaaaacgtg accagatcaa tgtataaagt ttcaattgat
    32881 ctttatctaa atattgtttg agttcatctg gtgtacgaag cacactcgtt ggacgcacag
    32941 cttcatgggc atcttgtgcg ccttgagcat ttttgatctt tcggtgatca tgtctagaaa
    33001 attcttttcc atacgtatct tcaataaatg ctgcggcctc tgcttttgct gtatcggcaa
    33061 tccgggtaga atcagtacgc atgtatgtaa tcaagccgac tgttccttgt ttacccaaag
    33121 tgattccttc atataattgc tgtgctacca tcatggtttt tcttgttcga aagtttaact
    33181 tacgggcagc ttcttgttgc aggctacttg tagtgaaagg attcgcaggg tttcttttgc
    33241 gctctttctt ttctactttt ttaacttcga agtctgttcc atcaattcta gcagtgactt
    33301 cttttacact ttgtgcatct ggtaatttct ttttcttacc gtcgattccc cagaaatttg
    33361 ctttgaattt cttgcgagct tttttaaaat taccgtcgat gctccaatat tcttctggaa
    33421 caaattctcg gatctctttt tcacggtcaa taataatttt taaagcgaca gattggacac
    33481 gtcctgcact taaccctttc ttgaccttac gccagagaat aggactgatc gaataaccaa
    33541 cgattctgtc taaggtacga cgagcttgct gtgcatctac taaatctaca tcgatcgttc
    33601 ttggttcctt aaaagctgct ttgactgcgt cttttgtgat ttcattgaag accacccgat
    33661 ttttttcttt cagatccaac ccaagtaggt acgctaaatg ccaagcaatc gcttctcctt
    33721 ctctatccgg gtcacttgcc aagtaaactt tttgagcttt ttttgctgcg gctttcaggc
    33781 ttttgatgac atcgcctttt ccgcgtatag aaatataatg gggttcataa ttgttttcaa
    33841 aatcgatacc cattttactt ttcggtaaat ctcttatatg gccaacactg gccattactt
    33901 tatagtttcg tccaagatat ttctcaattg tcttggcttt tgcaggtgat tctacaatca
    33961 ctaaatattt atacgccatt actgaatgga ctcctttcca ttgtcgtgtt cctactatta
    34021 aaagaggatt catacaaatc gtagctaatc atatccattc agaaaacgtt tgtcaagaaa
    34081 agcaaatgaa aagtatggtg ttattcttta aattctgcca agatatcttc acccgaaacc
    34141 gtgcaaactg caccgtcttg gatcaaatga tgacatccgg tagaatgttc tgttaaaata
    34201 tttcctggaa cagaaaaaac tgttcttcca agatccaatg cttgctgtgc tgttatcaga
    34261 gagccgcttt ttttcttggc ttcaaagaca catgttcctt tagacaaagc tgcgataatc
    34321 cgatttctca ttggaaaaca atgctttttc gggccggatt gaggaggata ttcactcaaa
    34381 agaagatgat catttgcaat cacctcttgc aagtcacgat tttcagcagg atagacttgc
    34441 tctatccctg ttccaatgac tgcgattgtc cgtccaccat gagagattgc tgcttggtga
    34501 ccgtatgtat ctatcccttt cgcgcagcca ctgacgatca catatccagc ttctatcact
    34561 ggttttagta aataataaac tgtttttttg gctaaagcag aagtgtgtct tccaccaaca
    34621 acgcttaaca tgttacaaga aagtaaagat agatcaccat tataaaacag tacaattggc
    34681 ggataggtca agtgaagcag ctgaggggga tatttgggat caaagcaagt gataaacgac
    34741 tgtttcgatt ggattttgcc ccagttagcg tgaatttcct gccaactttt gcgaaacagc
    34801 tcccggtgtt tggttatttt acctatctta atgatgtctt caaatccgat ttctttataa
    34861 ggatactgca tcatccagtt agcaagtgcc cattttcctt gactactgat tccttttgta
    34921 taagcaagtt tcaataaatt ttcttctatt tgatacatca taaaaccgcc tttcgtctct
    34981 ctttctaata agatacgtaa aagcggctgt tttttattgt aaatattttt ttacaggtgc
    35041 aaaactttta cgatggattg gcgtaattcc ttgtcgttca agtccttcta agtgttcctt
    35101 tgttccataa cctgcattat gcgagaaacc atatccagga taaagcacgt catattcttt
    35161 catcaattgg tctcgatata ctttagcaat gatacttgca gcagcaatcg acacagatcg
    35221 tgcatcccct ttgattattt tttcctgctg aataggcaaa tccaaggtca tcgcatcgat
    35281 caacaaatag cttggtacaa tggacaattt ttctactgct tggatcatcg ctaatttact
    35341 tgcttcataa atattcacat catcgattgt ctgctgatca acgatcccga tcccgattgc
    35401 cagggctttt tcttgaactt gttgataaag aagttctcgc tttttctctg ataattgttt
    35461 ggagtcattc agccctaata tgatctcatt tttcggcaag ataactgcag ctgccacgac
    35521 aggtccagct aatggtcctc ttcctacttc atcaatgccg gcaatccatt ggtgaccttg
    35581 tgcgtaccct tgcttttcaa agcaaaacat ttcttcatat ttttccttaa ttaatgcttc
    35641 ctttttcaat cgtcgttcaa aagaagccag tgcttgctgc acgcctttgc gtggatcatt
    35701 tcttaatgat tctagtgtag gatcatctat tctctgtatg cttttcaatc gttctttgat
    35761 actttggatg gattcagtca tcactttttt gctccatttc ttcgcaacga tccagtgtgt
    35821 atcgtccaag ttttccttga cgaatatcat gcacgactaa ttcgctgcca cgatcatagt
    35881 cttctttata cccacgtttt gctgtaatat ccatcagtaa ttccggtgcc aatttttctt
    35941 cttgctcgat tgataaacca taacgatcgc tgattcttcc tgaataatat cgggcaaaaa
    36001 agtctaatcc gtaaatcgct aaatcatcta aatggacaag ctggtctttg atcgcgcctg
    36061 tcagcgctag ttttttgccg atttcttcat cttcaaattt gggccataaa atccctggtg
    36121 tgtctaacaa ttccaactca ttacctaaac gaagccactg ctgacctttt gttacgccag
    36181 gcttatttcc tgtctgtgca attttcttgc ctactagtcg attcatcaac gtagatttcc
    36241 caacatttgg aatacctaag accattgccc gaatagcgcg aggcttgatc ccccgagcag
    36301 catctcttgc ccgtttttct ttcaatgctt ctttagccgc aggtactaga cctttaattc
    36361 ctttactttc ttgtgccgtg atagctaatg caagatggcc ttgtttacga aaatattctt
    36421 gccacagctt tgtctgttgt ggatctgcca gatccgcttt attcaataaa acaaggcgag
    36481 gtttttgctg aatgatctga tctagcattg gattacgaga agataaaggt aatcgtgcgt
    36541 ctaccaattc aaatacgatg tccacatatt tcattttttc agaaacttct cgtcgggctt
    36601 ttgccatatg tcccggaaac cattggatgg tcattgttct ctccattcct ttcataccgg
    36661 aatattcccc ggctttactt gtttttttct ttttcaatat aaattcactt ttttattata
    36721 aagaaattcc atctattagt taagtgaaag tgaaccagtc ctcattctat cacatcttca
    36781 cttttttgat gatgcaaatt tttattttgg tttctatata tgaatctaaa tttttgacag
    36841 cgtttcctaa ataagagatg atagacgaac aaaacagaaa ggagacgaaa caaatgaata
    36901 gtatggtttt tgttaatttt cctgttgctg atgtcaatcg ttccgttgct ttttatgaaa
    36961 agctgggttt taaaaaaaat gaagaatttt ctactgaaga agctggttca atggtatggg
    37021 atgacacttt ttggataatg cttctctctc atgattttta taaaaaattt ataaaagata
    37081 aagaaatagc tgataataaa aaaacaagtg gtgctttgat ttcgtttagt gttgaaaatg
    37141 cggatgaagt aaaaaaattt gctcaaattg caaaagaaaa tggtggtact ttccacgaag
    37201 tagatatggg aatgcctgaa gaagaaatgt tttcattaga agtccaagat ctagacggaa
    37261 atacattaga acccgtatgg atgaagatgt aagcagataa ctaatctgac gttttttata
    37321 acaaaaaaac aaaggcggat gatacgataa gtattctccg cctctatttt ttttattcgt
    37381 acaatctctt ttttacagtt tataaaagca gtcttctcac ccttttttta attgttagat
    37441 gccagtgtat gtaaatcacc aatgtgtcat gacacattgg tgattttatg gtatcctttt
    37501 attattaact gacaaaggag agaatatttt gaacactttg attgcaaaag acgtttttag
    37561 attgcccgaa atgaatgcaa gattgttgtc gacctctgct cttttattag cccttgatgt
    37621 catcttatac aagatagcga ttggtcctgc ttattttcaa atcacattcg gatttttaag
    37681 tatggcgctt atgggttatc tatatggacc gatctgggct ggtttgcttg aaatgttgtc
    37741 gaacacttta aatttcacga tatttggttc aggaacgttt caagctgctt ttcttatcac
    37801 ggctttcctt ggtggattta ttaatggctt atttttatat cataaaaaga taaacctgcc
    37861 ttccgtcatc gctgcccaat tattgattat gatcccagtc agccttttta tcaattcttg
    37921 gctgatgtct gttttgtttg gtgcagattt caaagtaatt tttctaggta gattcatcag
    37981 gaatatgatc caaatcccta ttcaaataat ggttgtttat tcatttatca aaactttaga
    38041 ggctagaaaa gtgtttaaac gagctgtttg attttacgta ctaaggtagt aaactgattt
    38101 tggattaaac aataaagcgt gcagtctcaa cagactgcac gctttattgt ttctcactgg
    38161 atccatttta tttcatcaag tggataatag acaaatcttg ctttacctag aatatcagtt
    38221 ttattgatcg tgccaaacga acgactatct tttgaaactc ttcgattatc tccaagtaca
    38281 aaataattat cttccggaag cttggattgt cccgttagct cttgtagtgt aaagtccgtc
    38341 gtataggatg catttgcatg atctgatttc aggtttttag ttagataagg ttccttaact
    38401 actttcccat tgatcttcaa ttgatcattt tggtagctga cattttctcc tggaagaccg
    38461 attactcgtt tgatataaat cgtgccatct gctaattgaa aaacaacaat atcaaatcgt
    38521 ctgatctccg aaaatttttc catcacaacc atatcacctt gcttcaacac gttttccatt
    38581 gaattgcctt ccactggtac cgggatgaat aaaaatcccc gcaacatgaa cgcaaggaat
    38641 acagaaacaa gtaagtattt gaatacaagc cagaagcgat taatatagcg ttgttttttt
    38701 gtcaatctct atcaatccat ccctcttttt ttcattcttt ctttattata agaaaaatat
    38761 caaaaaaatg cgactagata gctgaaataa aaataattct ttcaattagg ctattggaca
    38821 aaaaactttt ttgatcataa agtacaaaac tatctcttat atgtcatgat tattttctaa
    38881 atatttttcc catgcttcgt caaagatatc catggacggc aaatagtcga cattcagttc
    38941 cagataatta gaaatttctt cgtagctaga gctgtgctta ggaaattgga tgtctttacc
    39001 ggcttctgta gcgaaaacag ataaagcatc atgtgtgcca ccgcctcgca gtgtcattaa
    39061 ataatgaaaa aagcttcgat tcacccttcg ttcctccaat tttcttcgat aaaggcagcc
    39121 cggcgtgcat ggtttctttt aaaattttca ggatgctttt tataatactc ttgatggtct
    39181 tcttctgcta gataaaatgg ttgggctggt tcgatttttg taacgattgg ctgttcgaaa
    39241 cgtccacttt cagctaactg tttcttactt ttttcagcaa tgatccgctg ttcttctgtc
    39301 aaataaaaga tcaccgggcg ataattgtca ccgcgatcct cgaattgtcc gaaagcgtca
    39361 gttggatcag tttgctgcca gtaaagttct actaattgtt catatgaaat caatgttgga
    39421 tcatagataa tctccactgc ttctgtatgt ccagtcgttt ggctttttac ttgttcataa
    39481 gtcggatctg gtacatgccc tccagtatat cctgacatca ctgtatggat accaggaagc
    39541 gtgtcgaaag gctggatcat acaccagaag cagcctcctg caaatattgc tcgttccatt
    39601 atgattcccc ctctaatact actcatccga tgatttttta ttttcttttg tcttgctttc
    39661 agtactgctg gtgctagttt tgttggtatt tgagttgttt gaagcatcag aggtatcttt
    39721 tggcaaatat agactaaacc gaatgtcatc atttactaag tcgattttat ctgctttaat
    39781 atacatcccg ttttgcattc ggaattgatc caacctaagc atgatagtca gatcatctgt
    39841 attgacttcg atccaatctg gtaatttata gtttctcttg atcatattca tcacatcttt
    39901 gattggcaaa ctcaatgttc cgatagaaag acttctagct tttagttgga catttccgtt
    39961 ttccatcaca tacggatcaa aatataaata gaaatcgata ggaaaaccta gtacttcgaa
    40021 agtaccattg agtagtgctt cattttccaa ataaaattta tattcaatat cactatcttt
    40081 ttgatactca ctaaggaaaa agctgatgat ttgattgact ttttctttat ttgaattgat
    40141 cgttaagaca ggatctcctt gtctttccgt aagagctggt atttctggga gttctggttc
    40201 ccgattagca aaaatacggc tgcctaaaaa tacggtcgaa ccaagtacta ccccaagaag
    40261 gataaggaag gcgaatttcc agtaatttgt tttctttgtt ttgtttgaag atacgtcaga
    40321 tcttgttttc atgtttattg atcatcctcc ttctctaacc attggttttg tgtctcgatc
    40381 agctgatctc tcactgcatt tgccatcaat tgataaccta aattatttgg atggaaatga
    40441 tcttcttcat agagcacatt atttttgatg ccatttagat tttctgtcgt gctagttgtt
    40501 tgatctgttc cttcttctgt gacacctact tcctgattca atccttgata aagcaaatca
    40561 ttgattggga taaagtagca gttcggcatt ttttttgtca ccgtttctgt tcctttgttc
    40621 caattgttaa caattgtctg catgtcagtg atctcaggaa agttcaaata aaatggattg
    40681 tagatgccta aaatgtaaat aggtgcggtt ttattgaggg atcgaaattc ttccaatagt
    40741 tctgtgacat tttcctgata gtttttcagt ggctttttaa aggaattgac cgttaacccg
    40801 aataaattat tttggataac tttcatcaaa tcattaccgc caacagtcag tgtgataaaa
    40861 tcagctgttt tgatattgtt tcgaatttct tcttttgttt ttactcgctt taagatctgg
    40921 tcacttcgtt caccatttac accatagttt tctgtttcaa ccgcggtcaa attataacgg
    40981 tcttttagat catttgcgac aaggggaacg aatcctcctt gcttggtttg atctcctact
    41041 ccttcagtca gcgaatctcc gatagctatg tagtgaagtt tttctttttt atttggatct
    41101 tctctcacag tagttactgg tttcattagt gggccagctt tcggtataga agcagctaaa
    41161 cctgcataga tgatgatcgc aattaataat gggaacaaaa cgaggatcaa atgtcgtttc
    41221 gttaatttca ttttttcacc tcttgtattc gattggttct aatgttatca aaaattttat
    41281 caaaaaggta gtctttatga aaaaagaaaa caattatttt cctaatttta taaagaaaaa
    41341 gagaataagc tgcaagcctt tcaggctgag ggcttatcct cttttcgact aatctacata
    41401 atacatgatt gcaaacgcgt ctttaccagt atgcgtagcg ataaccggat tcgtatgcag
    41461 tacagggata tgcatgtccg ggaataattc ttgcaaaccc tctttgaatt cttgcgccaa
    41521 ttcttttgca tccgcatgtg aaataccgat ttgtcgcaca tttggcaatt ctttcagttc
    41581 atttttcaaa ttattaaacc atttatcgaa cgttttcttt cctcgcccct tagttacagg
    41641 gattaattca gaatgggcga aattcatcac cacgcgtatg ttcaaaacac tagacagcaa
    41701 accagttgtt cggctgattc ttccaccttt taccaagtta tctagtgtgg atattccgat
    41761 gtataatttt gtattgtctt gtactttttt gacttcttca aggattttct ctactgtttt
    41821 accttctttt gctaattcag ctgctcgaat tacctgaaaa gataatcctt ggtcagtggt
    41881 atcactgtcg ataaccgtta ctttcgtttt tgttagatta ctggcttgtc ttgctgcttc
    41941 tactgttcca ctcaagcctt ttgtcatatg gatcgaaatc acttcactgc cgtcttctcc
    42001 tagctcatca tacatcgaga tgaattctcc aattggtggt tggcttgttt tgggcagatt
    42061 ttttgctttc gccatcattt ccataaatct ttcgccgtct agttggtcat catcgggata
    42121 tactgttccg tcgatcatga tggatagcgg catgacacga atgcctaaag catcgcgtac
    42181 atttttttcc atcgtacatg aagaatctgt tacgattttt acatttgtca ttattttctc
    42241 tctctctttc tttaacaaga tgccttattc atgttaaact acatgtaaga caatttctat
    42301 ttttagtata acagacaaat aatgattttt cattaattac acctagtaaa ggagccgttt
    42361 tcatggaaaa aacgaaattt aatcgaacgt atgaaatatt aaatgaagtg tttaatgcag
    42421 tcacccatgg aattgggact ggattgagta tcgcgggact agtggttctt ttagtaaaag
    42481 gtgcccactt gcattcctcc ctccatattg tctcttatgc tatctatgga tcgatgatga
    42541 ttcttttatt tttaacgtct actttgtttc attcattgat ttttacaaaa gcaaaaaagg
    42601 tgttccaagt attcgatcat agttcgattt ttcttttgat tgcaggaagt tatactcctt
    42661 tttgtttgct gagtatccga ggatggctag gttggacttt atttgtatta atctggttgt
    42721 ttgcgattct tggcattata tataaagcgt tgacgttgca taaacgggag agagtatcaa
    42781 aagtatctac gatcatctat atttttatgg ggtggctctg tgtcgtggct gctgttcctc
    42841 tttatcactc tcttggaatg actggtgtta ttttgatggt agcaggcggg ctttcttaca
    42901 cgataggcgc attcttttat agcttgaatt ctatccgcta tatgcatgtt gtttggcatt
    42961 tgtttgttat gttaggtgca ggttttatgt acttctctgt tttattcttt acttaataaa
    43021 aaaaataaag ctatggatgg gacagctcta aataacagct agtctatcca tagctttttt
    43081 atatcgtcaa ttcgcctgtc ccgcttttta caggattctc attacgctga tacgtttcaa
    43141 attgatgcgg ataacgattt ttttcatcca tttctccttg actagtattg atcagtgacc
    43201 aatcagacca gtcaacaggt ggaaaataag catctccatc gaatacatga tggatgactg
    43261 tacggtataa tatcgtacaa aatggcagaa attcttgata aacagctgac cctccagcga
    43321 tgaaaaagat accgtctgtt tctttttcca gagcaagcac gtcttccaca ctatgcatga
    43381 catgcacgcc ttctgcttta taggaagaat ctctcgtcaa aacaatcgtc tgacgattcg
    43441 gcaacggacg gctacccatc ccttcgaatg tttttcgtcc catcactagt gtatttgctt
    43501 ctgtcatttg tttgaagaat ttcagatcat ttggcaaacg ccaaggaaga cggtcttctt
    43561 ttccaatcaa tccgttttca tcctgtgccc aaattgcagc taacattttc tcatcctttc
    43621 tgattctaaa cagcgatagg agctttgatc gccggatgtg ggtcatatcc ttctaattgg
    43681 atatcttcca tctcaaaatc aaatactgac tgcttttcct gattcaaaac taaagtcgga
    43741 aatgcgcgta tttctcggct caattgttct ttcatttgtt cgatatgatt gatataaaga
    43801 tgagcatctc ctaatgtgtg aacaaattcg ccaaccgcta aacctgtttc atgtgcaatt
    43861 aggtgagtca gcaacgcata acttgcaatg ttgaacggaa cgcctagaaa cacatcccca
    43921 ctgcgttgat acaattggca gcttagccgt ccctcttgaa cataaaattg aaacatcgta
    43981 tgacaaggag gcaaagccat gctaggaaca tcttccggat tccatgcaga aacgatcaat
    44041 cttctagaat caggagtctt tttgattgct tcgatcactt gtttgatttg atcgataaag
    44101 ccaccgtctt ttgtttccca gtgacgccat tgatagccgt agatgtgtcc aagatcgccg
    44161 tatgtttcag caaaggaatc atcggttagg atcttctcgc aaaaaagctt gctctgcttt
    44221 ttatattctt cattgaattc aggatctgtc aaacatctat ggccaaaatc agtcatatct
    44281 ggtccattat agtctggact tttgatgtag cgttcaaatg cccattcatc ccaaatatgg
    44341 tttttatttt gtaatagata gcggatattc gtatctcctt ttaaaaacca aagcaattcg
    44401 cttttgatca atccaaaagg tactcgtttc gttgttaaca aaggaaaccc tttttgcaga
    44461 tcaaaccgca tttggtatcc gaataagctt aatgtgcctg tgcctgttct gtcttcttta
    44521 cgatgccctt cttccaacaa ttttcttcct aagtcaagat acgcttgttc catccttttt
    44581 cctcctaatc ttctacccat tcactcaagt attcccaccg tgccattttt tcttcaagtt
    44641 gtgcttctgt ttcagatacg tcgttttgca attcttgtaa tcgagtgaaa ttatctcctt
    44701 gatgattcat ctcttcttgg agcaatgaga ttttttcttc aagttctgca atctcatctt
    44761 caatcgtttc ccattctttt tgttccatgt aagataattt cttcttttca gcaggttcct
    44821 tgctctgtat ttttggtttc gctttttcag caggctgctg ggtctctttt tgcttcagta
    44881 aataactgga catgtttccg taataaagtt cttgttttcc gtttccttgg aatactaata
    44941 acttatctgc taccttgtcc aagaaataac ggtcatggga aacagtgatc acagcacctg
    45001 gaaaacttct aaaataatct tccaaaatcg tcaatgttgc tatgtccaaa tcattggtcg
    45061 gttcatccaa taataaaaca ttaggttgct gaatcagcag tttcaacaaa aataaccggc
    45121 gtttttctcc gcctgaaagt ttgcctatca gtgtcccatg cataaatctt ggaaataaaa
    45181 atcgttcaag taattctgct actccgattt gactgccatc tgctgttttt gcttcttcag
    45241 cagcttcttg taagtaagca atcatccgtt tatctggtgc catttcttca ttttcttgtg
    45301 tataatacgc aagatgaacc gtttcaccga tagacattgt accgctatcc aggggaattc
    45361 tgccagctag aatattaagc aatgtcgatt ttcccgcacc atttttacca gtaataccta
    45421 gtctttcccg agattgaatc aataaatcta aatgttctag cagtgtttgg tcatttatac
    45481 ggtaactgcc atctttgatt tccagtactt ttttccctaa acgttgtgtc gctaggttca
    45541 gctctaaatc atcttcttgg tttacttggt acaagttctc ctttagatct tcgaaacggt
    45601 tgatccgtgc ttgctgcttg gtgccacgtg cctgtacgcc agccctcatc caagctaatt
    45661 cctgtttata aagccgcttg cgcttttctt cttgttctac ttctacacga tcacgttctg
    45721 ctttttctaa gacgtaagct tcataatttc ctttatactc gtataatttt ccaaatgaaa
    45781 gttcgaagat tcggtttgct actctatcta gaaaataacg atcgtgggta accatcaata
    45841 gtgcgccacg gtattgtttc aaatagtttt ccaaccactc gatcgcttca taatctaaat
    45901 ggtttgttgg ttcgtctagt aatagtaaat cgggttcatc aatcaacact tgcgccagac
    45961 taactcgttt tttctgacca cctgataaag tactgatttt tttatctaat tcactgattc
    46021 ctaatttttg caaaataatc tttgcgttgg tatctgtagt ccaagcatct tctttattca
    46081 tttgttcttc tgctttagca taacgttttt gcacatcagg gtcttctccg ttttccccta
    46141 gttcgatcaa tgcttcctca tatgctcgaa cagtttggat caaggggctg tttccttgaa
    46201 agactgcttg gagaacagtt aattcatcgg aaaattcagc tgcttgagaa agataaccaa
    46261 tacggtaatc agttggataa aacactgttt gccgatcacc gtcgctgcta tcgataccgg
    46321 caataatatt taagagactt gttttacccg tcccgttcgt cccaatcaac ccgatacggt
    46381 ctttttcgtg gaccaaaaaa gaaatctggt caaacaaatc tttttcacca taagtttttt
    46441 tgaggtcagt tacttttaat tctttcaaca tgttccctcc ttatcttgga tattgtatca
    46501 taaaaatagt gaacttcagg aaaatttttt tggtatttgt tctttttgtg ttctcaaaaa
    46561 aagaacagga ccgattcgat cctgttctga tatgttttgt tttttataaa acttgaaaat
    46621 ttttaccttt ttattttatt ggactcgttt tttttgactt tgctcgaaac gcaaatcgga
    46681 aagaaaagtt atcagatggt ttgttcatcg tataagattc taacaaattg atattcctgc
    46741 gatagctgtt cgcagaaaac gtcgtgattt tttcagcaac ttcgtattca tcaatgattt
    46801 ttctttcaag ataataacct cttagcattt ttttcgtaaa cagactatct tgctggatca
    46861 tccacgaaga aatcaaattc cccgagttca tttttattcc ttcaagtttg cgttgctgga
    46921 taaaaaattg aaccatcgtt tcatcataaa tatcagtcaa gttatctaaa ctttcaataa
    46981 tcaactgagt atttttttga tatgtctctc tgatttcttg gatatcttca tcactaataa
    47041 atgtctgacg atcagcatat cttctttgcc aaaacatttt cggatggaga acgattcgca
    47101 ttaacctacg gacaacaatg aaccaaaagc cgataaaaga caaaatctgg cttgtgatag
    47161 aatgttcgaa tcgagaaaga aaacgggagt aaaaacgata accattagaa gaaagcttgc
    47221 ccgaacgata actttcatcc aatccatccc gttcgatcga caaaatcagt gcttgtattt
    47281 cttgtacttc ttgcttttca tcatcggtta aatcttccaa gtacagatca cgtatccgtt
    47341 cttgataatt ttctatcact gcttcagtgg ctaaaaattc ttttgtatta cgatcaattt
    47401 cctttatttc ttttcgcaaa acttcaacga cctcttctaa aatcatcaaa gcattcaaat
    47461 ccgtgctttt cgcttcctct gtttccgtca gcataggcaa gacaatgatc cctatgacca
    47521 aagtcactaa gatgacaccc gccgtcagaa acaaaagcaa agaccgctgg taaaacatca
    47581 tattattgat tgaaaatggc aaaataaaaa tcgtagccaa actgactgtt ccctttacac
    47641 cgccaaatgt taagatcaag atctcgttca actgtttttt gaacttttta ctgccatctt
    47701 tgaatacata aaaaagactg atagaaatga atctgatcac aaaaagcatg acagagatta
    47761 atacgataat cgctaataaa agaccgtttg gatataaacc gtctccccat actggcgaga
    47821 acacttgcgt caattcgatt cctaaaaata taaatactaa tgcattcagt gtaaaagcaa
    47881 tagttgtcca tgtactgtgg gacaagctcg acaattctgc atcaaacaca gagattttcc
    47941 taaaaccaga agcttggaga atacctgctg ccactgcagc aatgattcca gatacatcaa
    48001 atgcctctgc caatacatag gctagaaaag gaagcaaaag ttcgatcagc agataccctg
    48061 tgacatcttg tgctgatgct ttttcgatca aatgaattat tttttgtttg aaccagacaa
    48121 gcaaaaagcc gatcaaagct cccccaatac tagaaactac tagactcatc cccgcgttta
    48181 ctgctgaaaa agatccggtg atcagcgcac caagagcaaa ctggaaggca gtaacaccag
    48241 atgcatcatt caaaagacct tctccttcca aaatatgcat cgccttttta gggatattca
    48301 ctcgtccaga aagagaactg actgctaccg catctgtcgg acctaacgct gctccaaaag
    48361 caaagcaggc agcaagtggg acacttggca acaggaatga taacgtcgca cctaccccga
    48421 caagggtcaa aatgactcct ccaaatgcca agaacaaaat tgtcccgaaa tttttgagaa
    48481 tcgaagaaat atctgctttt tctccttctc taaataacaa tggtgcaata atcataacta
    48541 agaacaattc aggttcaaaa tcgattgatt gtccccactc tgtcagacct aataccactc
    48601 caaggaaaat ttggatcagt ggagctggaa tcattggcaa aatgcggcta gctatgttcg
    48661 ataaggtgat cgttactgca aatacaataa ctaactcagc aaattccatc gtccatcccc
    48721 tttatttttt attttgtgta agcattttta aaaattgttc ttttttcttt aaaattttgg
    48781 tttcgactac ttcaacctgt gtttggttcc cctctaattc acactgtaca cgttttgact
    48841 ccaaacgaag cagatcatgt ttcagacgtt ccaactgacg atacatcaat atatttcttt
    48901 tacgcaactt acaaagtatt tgacggcggt catccatcga aagggcgcca tagcgatcat
    48961 gcaacagttt tttttgttgt tcaaaactct ctctcatttt ccagatctcc tatacacaaa
    49021 cttccatcat tatagcaaag ttctttttgg atgaaaaata tttcattgtt tcatcgttta
    49081 ttgctagtta gaaatttcca taaatttttc aacgcctcat tctattccaa atagtatcag
    49141 atatcaagta aaacttaaga aagataaaag tttctgacaa aaggatgttt actttcccat
    49201 tcctgccttt cttgttcttt tatcacaaca aaaaaatggg gctgcgacaa aaatcttgtc
    49261 acagtccctt attctgaata aacggtgtgg aagagacagc ctatcagtag taataagaca
    49321 catctctttc acagcctcat ttttgcgtaa aaatcgattt attcgaaaaa ttccccgtat
    49381 acatcttcta cacgttgatc tggattgatc acgatataca agttacctgt tttttcgctg
    49441 atttttgttg attgatattg attgtctaat ccttctgttc ctttatctag atatgggaag
    49501 tacacaagat caggtgtgcc atttcggtaa aggatttcca ttcgctcgat atcttcgtat
    49561 ttcaatgcgc gattaaacat gcccatttcc agtccgccta ggttgatatc atgtgtcgca
    49621 actgcgtccc cttcatggaa gatttcgatt ttaaatccag cacacggatg gatttcaaca
    49681 aattcactgc cattgattcg tccaaaactt gttgtgattt gtttgatcca aagatcgccg
    49741 atatgacggc ggttgatcgt ccaggtttct ccatttctaa aataaaattt tagcgctgtc
    49801 atttctttac tcattaaaaa gactccttta tgatgtaatt tattcttgta ctacctcagt
    49861 ttagcacaaa tttatgtaag tggtcacatc ttatgttttt tcttctaatg acgtatctgc
    49921 ccactttaag tagccaacaa agctgagcag atacagtcta gtgtttttta aatcaatttt
    49981 tctttcgata aaaaatccaa aacctgtttt ttatcatttt ttattctttg ttctacgacg
    50041 gctttttcag ctaattgcaa agcttcacta acccacttac caggtttttt tccagtttct
    50101 tctagcaaga ttttaccatc tactgctaat tcgcttaatg acttgatagg taaacgatca
    50161 taggattctc ctacggcatc catctgaggt gtttcgtcaa aatagatcat caattcttct
    50221 acttgcagtg catgtttttt gcctaagaag tacaattcga atggttccaa agctccagtt
    50281 tctcgttgtc gtagtccttg gacaagtgct tgaacgtctt taatcatttg gttagaacac
    50341 ttccacgatt tcaaaaagga acgaatctca ttttctttta gatccagttg gctgatcaat
    50401 aatgcccatg cttggctctc ttctttcaat gggacggatg gtaattcagc aaaacgtaaa
    50461 agtgcttcgc cttcttcttt caaaccggga cagcaaatgt agcactctgt ttcaataaat
    50521 gcatggattc ccgcggcccg ttcatttccc aagagcatct tgatgaattc cacatttata
    50581 cgttctacag atattttacc taatagctcg tggttttctt tgatggcgta gaaggtttct
    50641 tcctctaatt tgaaccctag ttgactgaca aaacgcaacc cgcgcatcat tcgtaaggca
    50701 tcttcatgga accgctcatg aggattgcct acagctcgca agatctgttc ttctagatct
    50761 tgcagaccat cgaacaaatc gatgatttct ccatcttctt tcaaagcaaa cgcattgatc
    50821 gtaaaatctc ttcttttcaa atcttctgcc aacgaacgaa cgaattcgac atgatctggt
    50881 ctacggtagt cctgataagt tgattccgtc cgaaatgtgg tgatctcata ttgttcatca
    50941 ttttctaata ccaacacagt tccatgttcg atcccaatat ctatcgtttt tggaaaaagc
    51001 tgtttgattt cttctggaaa tgcgcttgtt gcgatatcca catcatggat tggctggttc
    51061 agcaagatat cacgaacact tccacctaca aaataagctt catatcctgc attctctaat
    51121 tttttcagaa ctggaattgc cttttggtat tccagaggta attgttttaa tttcattttt
    51181 ccaacctttc ctgcgtgttt cttgtcctga gataaagact cagttgcatg gtgactgttt
    51241 gacaagtccg tttcagagtc ttcaaggcca ggaccacttc atcttgttta ctcgtcctta
    51301 cgctcaaagc gattatggtc tctttgattg aatttttcca tgtttttttc aaaaacttca
    51361 gttaagtcga tattcaatga attagccatg atcatcgtaa cgaataaaac atcaccaagt
    51421 tcttctgcta ccgagttaac tggttcagaa gcctttttgc ttttttctcc ataagtgtgg
    51481 ttgacttctc ttgccaattc acctacttct tcagttaatc gagccatctg agctaatgga
    51541 gagaaatacc ccaccttgaa ttgctggata tattcatcca cttcctgctg catactgtat
    51601 aaagaacgct ttttatccat ctttttccct ccaaaactat cttaccaaaa ctttaacgca
    51661 aatcctagat aagagcaatt gagaaaatcg aatttccatg ctacatttag gaaggaattt
    51721 ctaaatggaa attctgtgaa aatacataat tgaaagctgg aattcatatg gtcaaacgaa
    51781 aaacagtaaa agaagttctt tttatcatta taggaacaag tatttatgca tttggtcttg
    51841 tttacttgaa catcgctaat catttagcag aagggggagt ctcagggatc accttgatct
    51901 taagagcttt atttggtatt gatccagctt atacgacttt attaatcaac atcccattga
    51961 ttttactagg aggaaagatc ctcggtaaac gttccttggc ctatactgtt ctaggtacac
    52021 tttctttgtc attcttttta tggatctggc aaagggttcc actagaaatc aatttacagc
    52081 atgatctact gatcgtttct ctacttgcgg gtttagttgc aggtgtagga agcgggatcg
    52141 tctaccgcat gggtggaaca acaggcggca gtgatattat cgctcggatt ttagaacaaa
    52201 attacggcat cactatgggg cgttccctat tggcatttga tatcatcgtc ttacttgctt
    52261 cattaaccta tatcgacttg aaacgtatga tgtatacgtt gattgtttcg tatgttttca
    52321 gtcgtgtgat tgattcgatc ttagatggcg gatattctgc aaaaggtcta cttgtcgtct
    52381 ccaacaaaag cgaagagatt gcaccactac tgatgaccgg tctgcaaaga ggtgtgactt
    52441 tcctttctgg agaaggcgca ttctctggta attcaaaaaa aatcatctat atggtcgtta
    52501 gctctagtga attaactgaa gctaagagga tcgtccacga gattgacgaa aaagctttcc
    52561 tttcaatcat caatgtgcat gaagtggaag ggcaaggctt tacttatttg aagccacaga
    52621 caagattact gaaaaaacta taagaaaaaa gacaaagata ggctatgagg aaagattcca
    52681 catccagctg acctttgtct tttttagtac tatactattt ttaactaatt gttatgttca
    52741 cttacccggt tacttttctt ttgtgtctgc aaaaggatct ttcggttaac ttcatcagat
    52801 aatttcaaaa aagcatccct atctccatct tctagtgctt gatcgatttg agcataaagc
    52861 atttttagtt ttgcctcttc ttctttttct tgaaaatatc gttcaattaa ttcagtatct
    52921 tcttcactga ctgaagaatc ccaagaagaa aatggattgt cttctaagat agatagatat
    52981 tctcttgtct gccaagcatt ttcgaatata cattccacat ataaaggctt tttccaattc
    53041 aaacggattt catgaaaaat ctggtctgtg tccgtaaatt cttttccctg caaaaacaat
    53101 ttcatgggtt ccccttcaac agatagatca ctgatctgca gtcctcgatc cgcaaaattc
    53161 gccccttcaa caaagtggac attgcttaaa atcgcttcat gattggcaag ataattcaag
    53221 atccaaaaaa cttctcttcg gctaaaagat acatgattga ccatccacgt taaaaaattc
    53281 ttcttttccc gtacatcaat tagcattttt ctcacctctc tgttaggtca tctaataatg
    53341 acagtgcctc catatctcct ggttcaagtg ttaaataata agtcaataat tcttgcgctc
    53401 ttttcagctg cccttcttct cttaagaaaa aggcatactc tttcaagaaa tctggttcat
    53461 gtgatagttc atgataagcc tgttcatagt gtacagctgc aacggtaaag tcttctaatt
    53521 cattataagc atgggctagg ttccattctg cataaggatt agcagtttct tccatctgat
    53581 tgatcacttg tatcacatct tcatatcttt catcatccaa gtaaagatta cttaaagtaa
    53641 gtaatgtttc atcttgtttg tctcctactt ctaaagcttt cagtaaaagt tcttctgctc
    53701 gctgtctatc atgcagacgg aaagcatttt ccgaggccag gtgataaagt tcgacttggt
    53761 aaggattttc tttgattcct tcttctaaca ctgtttgtgc ttcttcaatc atttcttctt
    53821 cttgaagagc ttgtcctaga tatagatata acgattgata atgcggatta acttctcgaa
    53881 gttcttccag atagttgatt gcctgctgat tttctttcaa ttgaagattc gtaaaagcta
    53941 gctggaacag tcgatcatct gtcctttctt ctttcagtgc ttcttctaaa ggtacgatag
    54001 ctgcttcgaa ttctccttgc atacttaagg attgtcctaa acgttcctgc atcgagattc
    54061 ctgaaatttc atttatcccg cttgccaaca atgtttcata aaccactgct gcctctttga
    54121 aacgatcaac tgaaaaatac aattcagcta gcgcaaactg gatcaatggt tcatcaggaa
    54181 gcaacccagc tgcttctttc aattttgctt cactcacttc agggattccg ataacttggt
    54241 acaaatcagc tatcgccaat aagctttgcg gatagtaatc actttgctta tccacttttt
    54301 ccaggtattc aaaagctaag tcgatctcat tatcttcgat tgcaatttct gctaacggga
    54361 tgttcagtcc gtcattttct gggtattggt tgatcagttg ttcaaaaatc tgttttgctt
    54421 cgatcaaaaa gccaatagcc agcaattctt cgcctagttc agctaatata tctgctgggt
    54481 cttcttttaa tgctttttct aaaaagattt gtgcttgtga caagtcttca tctgataaag
    54541 cttgcaacat tttttcgcta tttgtattca tttcaattcc ctcttatctc actgacgatt
    54601 tgttgaaata ccgtcattgt tctcaataat tctttttcgt ttggatgttg gtatccgtct
    54661 attataccta ttttttctaa aacaagtatt tttttgcttt tttctgccaa aaaaagaact
    54721 ttttccaaat actccatctt tgaaatctgt tccagccagt ggattggata gccaagcaag
    54781 tccagccaca caaaaaagtt ttttagttgg aaatcaaaag gatatgcttg gagattccac
    54841 acgaaatgaa acatcattcc taaaaatttt ttcatactag cagaaagtag atggccattt
    54901 tcggtcagat aaaaagcttg ttcaaacagt ttaccataat ttgacaggtt ttctgcctct
    54961 aattgataaa aatagatcat ttcttcgatc atcccggcaa acggccgagt cgttaattgc
    55021 tttttatttg gatagttttt atacagattt tgcaaaaaac gatgatcaca aatcattccg
    55081 caacagataa aagtcaaaaa gtcaatctgc tttccgtcca cctgccgctc gctgattgtt
    55141 tgatcataaa cgatgcgttc tggcagattg atggtttgca gcactacacg atttggtagc
    55201 tgcaaaatcg tccgctgcgg tgttaatgct cggcttagag aacggatcga tacagggatc
    55261 atccatagtg atgaatcaag ggttgtatgt ttttgaaaaa aacctgccag atccatgatc
    55321 ccttcatttc caaatccgat gataaacatg gattgatttt cgggatagcg tttgacgaaa
    55381 tcaagcaggt tctttaattc tgttaaatga ttgcattgag tgttggcaca aatataccag
    55441 tcattgtttg cttgatttgc aaataacggg ttgatcttat ctgcaaacaa atcataatag
    55501 cgctgattcg ttaaaaataa gattggctga tcaatggaaa gttctcttag ctgactgact
    55561 agcgtttctc cgtaaaacac tttcgtcaac gcatcttcta cttgataatc aagttccata
    55621 cgcatccctc ctcttcttat ttttatttta ccattagtaa gcaaattcta gaaaagataa
    55681 gagcaaagct cacctcataa cttgcaaata aataaaaatt aaataaaata catgtgtttt
    55741 ctatgtatga catacggatt cggaatctct gtctcttatt tattcctttt ctgctaggaa
    55801 ataaaaagaa aagcacttgt agccctagag ccacaagcgc tttttcaact gtcttattta
    55861 acagcgtctt ttaatgcttt acctggtttg aatgcaggta ctttgctagc tggaatttcg
    55921 atttcttcac cagtttgtgg gttacgacct ttgcgagctg cgcgttcgcg aacttcaaag
    55981 ttaccaaaac cgattaattg aactttttcg ccgttagcta aagcatcttg aatagttgaa
    56041 aatacagcat ctactgctgc agttgcatct tttttagtta aatcagtagc tgaagcaact
    56101 ttttcgatta attctgcttt gtttgccatg gatagattca cctcctccac aagagatatg
    56161 atagaaatat catttagtta aaactttctg agtggtccag aagtttaaaa agaaatattg
    56221 attaacttca atattctgtt atcacgatat catatgaacc gcttaatagc aaggttttta
    56281 ccaattttca catgcttttt ttagtcatag aaacgtaaca aacgaaactg tctttttctt
    56341 ttgaaaaaaa aacgtcgata tggtaaaatg cctattttct cctacgaggg ataattcgga
    56401 tggacgtccc ttcaaaagta aatgcttttc tgatttgatt ttctaagaaa cgttcataag
    56461 aaaaatgcat caattcctct tcattgacaa aaacgacaaa tgtaggtggt ttgacagcga
    56521 cttgtgtagc ataaaaaatc ttcaggcgtt ttcctttatc tgttggtgtt ggattgattg
    56581 ctacagcatc cataatgata tcattcaaca cagccgaaga gatacgaaga ttctggttca
    56641 tacttacttg ttcgatcatt tcaggcagac gttccaaccg ttgtttagtc actgcagaaa
    56701 caaaaacgat tggagcgtaa tcaagatacc ggaattcatc acgaatctct tgttcgaaat
    56761 cacgcattgt attggtttct ttctttacaa gatcccattt attcacgacg ataataattc
    56821 cacgaccagc ttcatgggcg taacccgcta ctcgcttgtc ttgttcccga atcccttctt
    56881 cagcattcag taccatcaaa acgatatcag aacggtcaat ggcacgcatt gcacgcatca
    56941 cgctgtattt ttcagtattt tcgtatactt ttccgcgttt acgcatacca gctgtatcta
    57001 tcattaagaa tttctgacca ctttcagaaa cgaagtgggt gtcgattgcg tctcgggtcg
    57061 ttccttcaat atccgaaaca attacacgtt cttctcctaa aatcgcattg atcaaagagg
    57121 atttaccaac atttgggcga ccaatcaaac taaacttaat cgtgtcgtcg tcctcttctt
    57181 cagtctcttc agagaaatac ttcactgctt catctaaaat atcaccaatc cctagtccat
    57241 ggcttcctga aacaggataa ggatcgccta gccctaagga ataaaattca tagatatcgt
    57301 ttctcatttc tggattatct actttattga ctgctaaaat cactggttta ttacttctgt
    57361 ataaaatttt cgcaaccatc tcatctgcgt ctgtcacgcc ttcgcgtccg ctgactacac
    57421 aaatgattac atctgcttct tcaatcgcga tttctgcttg atgcttgatc tgatccataa
    57481 aaggttcatc gccaagatca attccgcctg tgtcgatcac gctgaattct cgacctaacc
    57541 attcaccttt tgcataaata cgatcacgag ttactccagg agtatcttcg acaatcgaga
    57601 tacgctcacc agcgatgcgg ttaaaaatcg tagacttacc gacgttcggg cggccaacga
    57661 ttgcaattgt tggatttgcc atattatttc ctcctcacaa gtttccaatc tcacttagtt
    57721 taacgaatgc attgccaact ttcaagcata gattgtcaat taaacgaagt atttttattc
    57781 cttattgaaa tactaatcgc ttttcaaaag aaaaactgag acaaaagcag ctgctttcat
    57841 ctcagtcaca gatacaaaat caattatttt tcagaatcat cggttgcttt ttcttctact
    57901 tcttctttca acgcatcacc taaaatgtct cccatagtaa atccagtatt ttcttctggt
    57961 aattcataag actcaacatt ttttggttct tcttctgaag ctggtttttc ttctaaagct
    58021 ttgatactca atgcaatacg atgttcttct ggatggatct ctaatacttt cactttcact
    58081 tcgtcacctt catgaagcac ttcatgtggt gtcgcaatat gtttatgtga aatttgagag
    58141 atatggacta gcccttctac tccagggaac acttcaacaa aggcaccgaa gcttgtcaaa
    58201 cgtttaactg ttccgtctaa tactgtgcca actggagctt ttgtatcgat ttctgaccaa
    58261 ggtccaggct gtgtgtcttt gattgacaag gaaacacgtt cttgttcagg attgatagac
    58321 aacactttga catttacatc atcattgaca gccaatacat cacttggttt tgctacatga
    58381 ctatgtgaaa tctctgagac atggactaga ccgtcaattc cgcctaggtc gacaaatgcg
    58441 ccaaaatcag taagacgtgc aacacgtcca ctgagaacat ctccctcatg gatagttgaa
    58501 agaatttctt ttttcttttc ttctctttcg ttttccacta ccgctttatg cgataagatc
    58561 aaacgatttt ctgatggttc gatttcgatg attttaaagc tcaatgtttt gcctttatag
    58621 tctgaaaagt ctgcaacaaa atgatcttcc accattgatg cagggacaaa accacgtaca
    58681 ccgacgtcaa cgactaaacc gcctttgaca acatttgtaa caggtgcttc gatgaccttg
    58741 ccctcttgga aatctctttc gatatcttcc caaacttttt tagcatctaa acggcgtttt
    58801 gaaagtagat agctgccgtt ttctttatct ttgccgatcg tactgataac gactaaatct
    58861 aatacatcac cgacttttac tacttcgctg atatcttcta ccggcaaagt tgataattct
    58921 tttgccggaa cgactccttc aactccagcc ccttcgattc cgacaatcac ttgtttgtct
    58981 tcaatgacta aaacttcgcc cttaacaaca tcgccaactt ttacttcttg tacgcttttc
    59041 attgcgtctt ccattgactg gttgttctct tgattttgat caaattctgt cataacactt
    59101 gtcctcctaa ccaacattct gccgtaagta cggtactgtt tttagtttaa ttgattattc
    59161 aaaaaaaata aagcgatttc gttcgttttc cttgaaaaaa caattgtttt tcattttttt
    59221 tcttaattta aaaaagaaga taaccttttt tcaaaacaac agcttttatt gctgcaacga
    59281 cttctggaat cgatttgcca gtcgtatcga tacgaacagc atcctctgct tgcttcagcg
    59341 gagagacgtc ccttgttgaa tcataatggt ctctttcctg tatctctttc gtcagtgttt
    59401 caagatcagt cggaattcct ttttcttggt tctctttgaa acgtctttct gcacgctcac
    59461 ttacgcttgc tactaaaaag attttcactt ctgcattcgg taatacagct gtcccgatgt
    59521 ctcttccgtc catgacaacg ccaccgcgtt cccctatttt tcgttggaca gcaactaatt
    59581 cttctctgac ttttccatgt gcagagactt cagaaacagc ttttgtgaca tctggttgac
    59641 ggatttctaa agtcacatct tttgatgcta tgaatacatg ctgtccatct tcttgttgcg
    59701 aaaaagagat aggatacttt ttgatcagcg aaactagccc ttcttcatct gaaaaagata
    59761 cattgttcgt aatagctaaa taagttactg cgcgatacat ggcaccggta tctgtataaa
    59821 tataattcaa ttcttttgct aatatcttgg caacggtact tttcccagat gaagcaggcc
    59881 cgtcgattgc aatactgatt tgtgtcatga tataactcct ttttctcaga aaaaaagccg
    59941 caaagcgcgg ctattattat ttaattctta attcttgacc agggtaaagc ataaagttgt
    60001 ttggatctaa gccattcaat tcaaacaatt gatcagtggt gatccctgca cgctcagcca
    60061 cttgttttgg accttcgcct gcttgaacag tcgttgttga accggctgca gctgatgaag
    60121 aaggtgttgt ttctgctgca ttgctgcttg aatcccctgc ttgataagtt gcctcacttg
    60181 aggaagtcgg tgttgtctct gctgcaatac tgctttctga cgttacacct gtatcttgag
    60241 acacagtaga ttcttccgcg attgtactag attctactgt tgaagtctca gttgactcct
    60301 cttttgttgt acttgtagaa ctttctacta ctgatgtcga agtttcagaa gaagttgctg
    60361 ctgttgcatt gttgcttgat ccatttctga tccagaaata agcacctgct ggaatagcga
    60421 tacataagac cagtaaaatc aaaaatagcg aaagaaataa tgtatttcct ttcttttgtt
    60481 gtctctgaga acttcttgat gaaacttcat catctgtatc gtagattggt tgttcccatg
    60541 gttcttgtgt ttcgttattt tctgtagatt gatgtctatc ttttctgctc actgttttac
    60601 ctcctaaact ctatcgtgtg tattatacca taggaaaaag tgtcttgtcc taaaaaatca
    60661 atgttccatg ttttttttaa ataaatttag taaaatcgtt ccccaatgaa gttgttcagt
    60721 cttagaaaaa agcttcctct ttggcagaag ttctgctttt gctccatcaa tatcacaaca
    60781 attctgcggc ttttcggaga gtttttcgcc aaaataagct aagatgaatt ttctgcggca
    60841 gttttcttca ttaatatagc gaagcatctg ctgcaggcgg aattcttttt ctttttcctg
    60901 acgtttgagc cgttccaccc aattttctgg tttttcagac tgctggatca gctccatcca
    60961 ttttttttgc agctcatcaa agggagcttg ctctgtggca tattccaaat aaagctcaaa
    61021 actttgtcgc tgttctctag aaagttgatt aaagaaataa tggatacgtt catccccact
    61081 ttgataaaaa agaattgctg cactttcttc ctgatctctg cctgctcgac cgatttcttg
    61141 tacatagttt tctagactgt ctggcaaatc ataatggacc acataacgga tatcagattt
    61201 atcgatcccc ataccaaatg cattcgtagc aatgagaaac tgcagctgat tttttacaaa
    61261 ctgctgttga agttgtcttc tttgagctgc atcaagacca ccgtgatagt atccaactgt
    61321 aaaacgttcc ctgaataaat gatacaatcg ttcgacttct ttttttgttg cacaataaat
    61381 gattgccgct ccttgtgctc tttccatgaa gtgttcaagt tcttgttctt tttgctgcgt
    61441 tttccgaaca aaaagcgaga tattttgccg attgactgat tgtctgatct cttttggtgg
    61501 tcgatcaaat agtacatgac gtatatctct tgctactaaa tctgttgctg tcgccgttag
    61561 tgccagtgtg accgggtttc ctaaaagctt tcggattttt cctaactgtt gatattctgg
    61621 acggaaatca actccccatt gagacacgca atgagcctca tctactacat ataacgcaat
    61681 attttgtttt ttcagatgct ctaaaagaga aggattagtc aacatttcgg gactcaaaaa
    61741 caaaaattta tattgcgata gatgacggag gacgtatctt ctttcagatt gcgaaagtaa
    61801 actattgaaa gcagctactc gtttctcccc tcgtttttgt aattgcgtca cttgatcttc
    61861 cattagagaa agcagcggtg acacgatgat gaccagacct tccattaaat accccgtcaa
    61921 ttgatagcaa aggctttttc ccgttcctgt aggcaaaata gcgagagtat cttctccatc
    61981 aagcaacgcc tgaataattt cttcttggcc gggacgaaat gaatcaaatc caaaatattt
    62041 ttttaattca tttattaaca ttctgtatcg cttcctttct caatagatag atttgataca
    62101 aacgaaattc tccataatct aattgtccat ctacattcca ttcgctaaag cgccactctc
    62161 gcacggaatc cttatttggt tccaaacgtt cgattgtttc tgcagagaga atccactcgt
    62221 atggaaaatc atcaaaaaac aaggcccact caataagatg atctgttact gttcctcttt
    62281 ttaaatgacg gattgccatg atctggtcaa ttgtctgacc attcataaac atctgcttgg
    62341 tgatcatcat gctttgattg aaattttgct gtaataatga atcgatcaaa gcgtgccaaa
    62401 gcgaatctgg ccgtttttcg atttgtgcta acaaaaggtg gatacatctg ctttgttgca
    62461 gataaaccgc tgactcatca ttgttttttg ccagctgata aggaagcagc cctgttcgct
    62521 catttccaga taattggtta gctaaaaaat ctgctgcttc ttctggtatc tccgaaaaca
    62581 gctgcaccaa actctcatac gcagtatcaa tcaaaatttc acgtggcaat tggctttcac
    62641 taagccattt ttttagttgg aaagtataaa aaggacttgt ctctgctgga agatagtctt
    62701 gaatacccgt tgccagatta gaaattactt gaacagcaaa tttaatgagc cgccaactag
    62761 tttcccctgt tctgccatag cggtcaaaac gcaaaccagt atgttctatt tgatgttcgg
    62821 acaacatatc agcccctgca ggcgttagct ttgcttcatt ttcatttatt tcgatccaac
    62881 cttgctgcgc aattttttgc aaaatttgat aaaacttatc ctgcttcaat tctggaaaac
    62941 tgttatggat aaacaaaagt tcgtgggtaa atccataaat aagtactgaa gtcgttcgtt
    63001 ttcccacaag gagttggtaa agagaactaa tccgcagctt gtgtcctgat gaaaatagcg
    63061 ataaaataaa aacaatcata ttattctcct taagttagga tggttagaaa tgtcactact
    63121 atgtaaactt gtacctgaac gctgtattgc atgcggtctt tgtcaaatcg aagcgccaga
    63181 tattttcgat tatgatgaag aaggaatcgt tttatttgcc caagaaccag aggctcatca
    63241 acagttcgtg atgccggaag aagaaacata tgtaaaaaaa gcgtatcaaa aatgtccagt
    63301 tcgagcgatt ttattagaaa ataaaatata aatataaacg aaactttaaa aacgtacact
    63361 aagttctcta aacttgaaaa taagccggga tctgtttctc ttgttccgtg aaatcccgac
    63421 ttattttgaa agattcattt gctatctata gttaattgac tagttttttc acggacccta
    63481 taggacccat ttatattatt tcaacttttt cagccagttt tccaatgtat tgacgatcac
    63541 agtttgctgg tctgcgttag aaatttctgc ctctccatct cctttttgct caccatagct
    63601 gccaaaacct ccatgatttc cgccattgat tgatacatac tctgttcttt ccggtaaata
    63661 ctgcttagct tcttgataag cttcctgatt caatacttta tcttttgtcg ccgtgatcga
    63721 taaaacagga acagctgatt ctgtcaatgt tccttttttg tcgggataac ttgccatgaa
    63781 gaatacccct tttaaatgtt tgtctgaatg attcttattg acataacgac ttgccattac
    63841 gccacctaat gaatggccac cgatcacata atcggaattt ggaaaatctt ctttgacctt
    63901 atccgctttg tttccgccca tcactgctag atcaagtggc attttgacaa tagcgactga
    63961 aaagccgttt tttgctaaat cttgcgccca aatactataa ctttctggct ctacgagagc
    64021 accaggataa aaaataagta atggagactt tccatgattc tttttctctc cttcaaaaaa
    64081 taagtaatct tctttgtttt ttccttcttt taccaacact tgcgcttctg acgatggttc
    64141 gtacgtattt tgctgtatat agtaataacc ggctccaccg agtaatccta aaatgatgac
    64201 taagccaatt agtattcgtc taaatatttt cactttctcc caccttttct atctgagtga
    64261 cccctttttc ttaatcaagt atgattatac cttaaaaaaa taagagagaa atgcaaactt
    64321 tccagcatca aataaaaaaa gacggaatat ccatttgaat atccgccctt tttgtatgtt
    64381 tatttttatt tagcacataa acgatacaca gcttctgcat aaatttccat tgctttatac
    64441 atactactta attcccatcg ttcattcgcc tggtgcataa agtcaggagt atcagggaac
    64501 atcgcaccga atgccacaca ctggttcatc gtacgagcaa aagtagcgcc gcctgataca
    64561 aacggttcag tcatgtctcc agtaatatcg cgatatgtcc ccaatagatt tttcactaac
    64621 tcactgtcta gtggcacgta taatgaatca aggaagtcaa attcttcata agtcaaccca
    64681 tatttttctg ctgttttagt taatttagct actaaatcat ctttcttgaa tgtaacaggg
    64741 attctcatat ctacaccgat ttttgtttgt tctggtgtga tttccaaact tgcaaagttc
    64801 atcgttagct cgccggattg ttcatcttct gttttgccca cgacagcttc accagttgca
    64861 ttttcttgaa ctaattttcc taagaaattg attgggccaa aatcaaatac ttctgaaaga
    64921 gcaattgcca gacgagaaat agcattcact ccttgtgctg catctttcgc gtggatactt
    64981 ttaccaagaa cgacgatgcc ttcaccttgt tcttcgaaat cgaattcgtg ttttttcaat
    65041 gcttctttta cttcagaaag cttttctcca gagtaaggag ctgcatcagg aacaacattc
    65101 aacgctcctc cagcttttac agaaaactcg ttcgttcctg gtcctgtcaa gtaagcttgc
    65161 aataagcctt tttctgcata aattaaagga aattcagcat ctggcgcaaa tccttgcgta
    65221 attccttctt ctttttcgtt atatttttct aaacaacgcc ataaattttc ttcatctgta
    65281 ccaaagataa aacgaatacg tgtcttgaat tccacgccag catcaatcaa agctttgacg
    65341 gcatacattg ccgcaataga aggacctttg tcatcttggg atccgcgacc aactaaccag
    65401 ccgtctttta tagttggatc gaatggtttt gtttcccaat tattttcgtc ccctgctgga
    65461 acaacgtcca tatgacacaa gataccgaat aattcatctc cagagccaat ctctgaataa
    65521 ccgtaatagc cttctggatc tttaaatgtt ctaaatccta gcttttcact gatttccaat
    65581 actttatcca aagcttcaat cactttttta ccgaagggat gtccttgtcc tgaatctgct
    65641 tcatctagta cggaaggaat tcggatcaat tcgctcaatg attctaatgc ttgttcatga
    65701 tgttgttctg tcacaaattt tttcatgata ttatcctcct aatatgttaa aaagggtcat
    65761 gtcaaattcc tccgacacaa cctcttcttc tcaaataatg acgttttaag cctgctccat
    65821 cagcaagcag aatgttctta acaaatgatg aaagaaaaaa cactcactga atggagctat
    65881 tgacttatcc acgtgcttat cgatagccgt ttatcggttt cttcattctt atgatagacc
    65941 ttgtacctgt atttgtctag gtttagaaca ttgctgctac acctaggatc acacagatgg
    66001 ctacaaataa tatcgcaatt aatttaccgg taaatttcca ccacactgaa acatcgaaac
    66061 gagcaattgc tacagcaccc attacgatag cagatgttgg tgtaattaag tttactaaac
    66121 cagatgcaga ttgataagca gtgattacta aatccttacc gacgccggca aattcaccca
    66181 taggtcccat gattcccatt gttgcagcag ctaagccgga agttgaagga atcaagaatg
    66241 acatagggat atagaaaata aatgtaataa tgatgaatac acttgaagat aatgaactta
    66301 atccttgttc gccccaatgt aagatggtgt ctgtgattaa tccattgttc ataaccactt
    66361 ggataccacg agcaacagct actacgattg ctacaccgat caaatcagaa gcaccagcta
    66421 aaaattcaga gacaaattca gactctttca tgccataagt gattgctact acgatggaca
    66481 ttactaagaa taacatagta atttctggga agtaccagtc acctaatgga agcatgcttt
    66541 tacctagaac cgtacctagt accggaaggt ttgttaacca gtttgtcaat gattcaaaaa
    66601 tcgtgaaatt cgcattcaag gttgtccaag gaatcaaact gatgatcatg ataccaaaag
    66661 taataaagaa caatacatta acatgttttt gttttttcgt gattacttct tgacgaccga
    66721 ttgcttcaat atcgaaatgc ttcatatctt ctttacgttg gttgtatact aatgattttg
    66781 ttggatcttt ttcgatcttt gatgcataac gatacacata tacaatagaa atagctaaca
    66841 aaataacgaa catcaagaat cgaagaccaa taccttcacc catcgaaatc ccaacagctt
    66901 gtgaagctac gcctgttgca aaaggattta ccgttgaagc tagacagcct acttgagacc
    66961 ctactaatac gattgctaca gctactactg tatcaaagcc tacagccatc atgactggga
    67021 tcagtaaagc atagaatgga atcgtttctt ctgccattcc gtaagtagag ccgcctaatg
    67081 caaataacag catcaatact ggaataagca ttttttcttt tcctttgaat ttcttcacaa
    67141 ctgaagcaat cccggcatct agtgcccctg ttttgttgat aatacctaaa aatccaccaa
    67201 caaccaaaat gaagaaagag attgggattg cagcaggtgt ttctttagtt agctcccccg
    67261 ctggtacacc tagcatccca ttgattggcg ccatgaaaat atcccacagc ccttgaggat
    67321 tttgttgtac tcgttcatat gatccagcga cgatgttgcc tgcatcgtct acactatagt
    67381 gcccagctgg tataaaccaa gtaagtacag cgattactgc aataataata aataagaccg
    67441 tatacgctga aggcatttga aattttttct tttttgtttg ttccatcttc ttcttccttt
    67501 cttttccgtt agagacaaca attttggctc taatgttatt ttatcaaaaa gagtatcaga
    67561 acaaaaataa taacacgcat tttgtaaaac ttttgttcaa aaagttcgtt tttccctatt
    67621 ccctcctctt ttttcaggtt tttaaagctt tcttcttttt cattgtagcg tttccttttt
    67681 tttataaaca aacattttcg tcttttaaaa ggagaagaat ttcacatttg caaagaattg
    67741 attgattttt atgcataaat caaaaaaata ctcaaaacaa acaaataaaa cgtttacatt
    67801 attgcatgtc ttgtattttt ttccaaaaaa aaagaccaag aaatttcttg atctttttga
    67861 tatttatttg actgctgtat gacgttgttc gaactgatgt tgttttcgac ttaaccatgg
    67921 aagaagttgc gcatgcagca ctaaaaagac agcactcacg atgaatcctt tgatcaagtt
    67981 gaaaggaacg atcccaatca gtacatagtt tgctaaagac atgcccagca tctgtgttgc
    68041 gttcagccct aaaaacatta agtaaagagg cgtaataacg aaataatttg cgatactcat
    68101 aaaaatagtt agagcgatgg ttcctgtaat gacacctaaa aatttgtttc ttcctttatg
    68161 ctgtttcttt acactaaaga aataataaat cgggaatgta aagatcgttg ttgataagaa
    68221 actagcagtg tctcctacca aattatccgg agaaaaacct gtagtcagca gatgtaatac
    68281 tgaacgcaag aacgctgttg caactccggc cgctggaccg aataagaaca tgctgatcaa
    68341 taccgagata tcactaaaat cgatcttcaa aaaactaaaa gccggcatga tcggaaaagc
    68401 aaaatactgt aaaactaatg cgatcgcagc aaacatcgct actgcaacca ttttctgtac
    68461 acgggtgttc ttcatttgaa atcctcctgt taggactcct cttcagcgaa ctttttgacg
    68521 tttctctcca aatgaaaaaa ctctattttc cagggaaaat agagttagag ttatttgatc
    68581 aagcgtcgtc aaataagctc tatcttcttt atccagacta tactgtcggt atcggaattt
    68641 caccgattca gctatttttt tgcaaaatag gtcgtggact ataaccaccg gtcgggaatt
    68701 tcaccctgcc cctgaagacg aaccttatat aatttttgtt tacatattca ttatacatat
    68761 ctattcaaaa aacgcaacat ctaacactta taaaaagtaa gtgttcattt tgagtggttc
    68821 agcaaactgc tgacttcttt tttgttcagt tcacggtaat ccccaggacg taggccttgt
    68881 aaagtcagat ctccgtattt ttcacgtttt agtttttgca caggaagacc aactgcttga
    68941 agcatatttt tcacttgatg attacgtcct tcgtggatcg tcaattccac gatactgtgg
    69001 tttgtcttag gatccactga taaaatttgg aatttagctg gagatgtttt tcgtccttcg
    69061 atctttattc cttttgtcaa aggtgcaagc atcgattttg tagcgatccc ttttaccttt
    69121 gcaacgtaaa ctttatccac ttcatgtttt ggatgtgtca ggcgctgagc aaaatctcca
    69181 tcatttgtca gtagcaagat ccccgaagta tcgtaatcca gtcgacctac aggatagata
    69241 cgttctttta ccatcggcaa aagatccgta acaacttttc ttcctttgtc atctgcaaca
    69301 gcagaaataa ctcctttagg tttgtacaat aaatagtaac cgtattcttc ttgataaatt
    69361 gggacttcat ccacttccac agtgtcatgt ttcccaactt ttatccctaa ttcccttaca
    69421 acttgtccgt ttacttttac acgtcctgca aggatgaatt cttctgcttt tcgacgagaa
    69481 gtgatgccag cgtgggcaat tactttctgc aatctctcca ttacaattat tctcctttat
    69541 tcattccatc aaagaataga tctggtgaca cgtcttcttc aagtgaaatt tccatttctt
    69601 gtgtatcagg cagttcttct aatgatttca aaccaaaata atctaagaag tagccagttg
    69661 ttccatataa tatcggccga cctggtcctt ctactctacc tttttcttca atcagtttat
    69721 gggcagctag acgctgtacc gctcctgaaa cctgaactcc tcgaatctgc tcgatttcag
    69781 ctcttgtgat tggctgttta taagcgatga ttgctaaggt ttcgacggcg gcttgagata
    69841 atgtgtttga tgtcccttgc gcatatcgct taagtaaggg agccagctct tttttagtcg
    69901 ttaatacata atggctttcc gtttcaaaaa tatgcaaagc tgagtgcgag ttttgagtgt
    69961 aagattcttt taattctttc actaaacttg tgacttctgc ttcgctgaga tttaacagtc
    70021 cgcttaattc ttcattactg atcccttcct cgccaacaat aaaaagaagg gcttcaagtt
    70081 cacttaattt cgtcatgttc ggtatctcct actgctggat aaagcataat tgattcatag
    70141 ttttcttttt gttgcgcaat gatctgccct tttttcatca attctagcaa agccataaaa
    70201 gtagtgacaa cttcactttt agaaggtgac tcaaaaaaag aatcgaaagt acagccatgc
    70261 gcatttcttt ttatacgctc ttcgataaat accattcgtt cttcgatcgt tgtgtcatcg
    70321 ggcgtgatcg ttttttccac tttttgagaa aatttcttac gttctaagat tttctgcatg
    70381 gcacggatca aatcgatttt tttgacttgt cctcgcttca acggcttttc agcatccgct
    70441 aacccatcga tgttcatagg ttcttttgtg taataaagac ttcgttcctc tgctttttct
    70501 gtcagtcttt cagctgcata tttatattta cggtattcta aaagctgagt gaccaattct
    70561 tctcgaggat cttcttccca taattcttca tcgtctgtga cgaattcttg gacaggaagc
    70621 aatgtcttgc ttttgattgc catcaatgta gcagccatca ctaagtattc tcctgcaaca
    70681 gctagctcga gtgttttcat tgtatggata taattcatat attgctccgt gatcgtagcg
    70741 atcggtatat catatatatc gatttccatt tgctgaatca gatgaagcag cagatcgaga
    70801 ggaccctcga atacatctaa tttaatattg atctccgtca actcattcac tctttcttct
    70861 ttttctttgc tagccatttt ccaatgtaag gctctgtgat ttcagttgca cggatggaga
    70921 catccgggta cttttcctgt aattcatcta acatttgaaa gcccatattc tcaccgcgat
    70981 aagacggatt caaagaaatg tcatggatga tcagctgatc gttcgttgcc cagtaaatac
    71041 caataatccc ttgaatgttg gttgaacctt ctggcgtaaa gaaaaaaagt tcataatcgt
    71101 cttcagattc gtacgtatca atctccttca acaaagaagt tttacctgtc agtttcttat
    71161 ggaaactcaa tagtcccata gcaattttac ggttttcttt ccggtaatgt gttaacatct
    71221 tctcaccttc ctatgactaa gcccttggaa aatgctgctt ataaacatcc gtcattcttt
    71281 tcttcgtgat atgtgtataa atctgagtcg tagagatatc cgcgtgacct aacaattcct
    71341 gtactgtccg caaatcagct ccattttcta gcagatgtgt ggcaaagcta tgccgcagcg
    71401 tatgtggtgt tacttctttg taaatcccag cctctcgtac taactgcttc agatttttcc
    71461 agattccttg ccgagaaaga cctttcccat gattattgac aaatacatgc atttcagatg
    71521 cgtcctttac aagtaatgga cgtgcttcgt ctaagtagcg ttccagccat tggatcgcat
    71581 aatcacctaa aggaatgatc cgctctttat ctccttttcc aactgtctgt accagtccaa
    71641 gagaaagatg aagatctccc aatttcaatc caatcaattc actgacgcgc atcccagtag
    71701 catacatgac ttccaagatt gcacgatctc ttatccctaa cgtttttgtc gtatcaggtg
    71761 cttcaatcag cttttctact tctgtcagag tcaatgtact tggtaatttc tgtgctttct
    71821 tcggcgtatc gatatgttgc atcggatcat gatcagtgat acgctcttgc cgtaaaaact
    71881 gatggaatct tctgagactt gagatcatcc gagtaacagt tgctgtcgct tttttttctt
    71941 catgcaactt ctccagaaaa cggatgacta aaaagcgatc gacatcctgc catgaagcaa
    72001 ttttctgctc ctgtagaaaa tgcaagtact gttccaaatc acgttcatag ctttgtcgtg
    72061 tattggcgga caatccccgt tcaatattca agtagtggag ataatcgttg atttgctctt
    72121 tcataataat ccccctcatg cctctctatc atatcagata ccgcttcatt ctgatagtct
    72181 ttttccataa tctgagcaaa gaaaaagccg tctagacact cagacggact ggtttcttt
//
LOCUS       DBBGSP010000008        66900 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000008 DBBGSP010000000
VERSION     DBBGSP010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 66900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.008"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(25..327)
                     /locus_tag="ACIZE9_000619"
     CDS             complement(25..327)
                     /locus_tag="ACIZE9_000619"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6092510.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(352..2445)
                     /locus_tag="ACIZE9_000620"
     CDS             complement(352..2445)
                     /locus_tag="ACIZE9_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC6092511.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(2934..3698)
                     /locus_tag="ACIZE9_000621"
     CDS             complement(2934..3698)
                     /locus_tag="ACIZE9_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HGC6092512.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(3809..4678)
                     /gene="mdcB"
                     /locus_tag="ACIZE9_000622"
     CDS             complement(3809..4678)
                     /gene="mdcB"
                     /locus_tag="ACIZE9_000622"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HGC6092513.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(4703..5779)
                     /locus_tag="ACIZE9_000623"
     CDS             complement(4703..5779)
                     /locus_tag="ACIZE9_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGC6092514.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(5803..6396)
                     /locus_tag="ACIZE9_000624"
     CDS             complement(5803..6396)
                     /locus_tag="ACIZE9_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HGC6092515.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(6400..8076)
                     /gene="mdcD"
                     /locus_tag="ACIZE9_000625"
     CDS             complement(6400..8076)
                     /gene="mdcD"
                     /locus_tag="ACIZE9_000625"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HGC6092516.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(8066..8365)
                     /locus_tag="ACIZE9_000626"
     CDS             complement(8066..8365)
                     /locus_tag="ACIZE9_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HGC6092517.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(8467..10118)
                     /gene="mdcA"
                     /locus_tag="ACIZE9_000627"
                     /pseudo
     CDS             complement(8467..10118)
                     /gene="mdcA"
                     /locus_tag="ACIZE9_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
     gene            complement(10125..11036)
                     /locus_tag="ACIZE9_000628"
     CDS             complement(10125..11036)
                     /locus_tag="ACIZE9_000628"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGC6092518.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            11156..12013
                     /locus_tag="ACIZE9_000629"
     CDS             11156..12013
                     /locus_tag="ACIZE9_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC6092519.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(12200..12562)
                     /locus_tag="ACIZE9_000630"
     CDS             complement(12200..12562)
                     /locus_tag="ACIZE9_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGC6092520.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(12751..12933)
                     /locus_tag="ACIZE9_000631"
     CDS             complement(12751..12933)
                     /locus_tag="ACIZE9_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092521.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            12908..14347
                     /locus_tag="ACIZE9_000632"
     CDS             12908..14347
                     /locus_tag="ACIZE9_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092522.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(14354..16906)
                     /locus_tag="ACIZE9_000633"
     CDS             complement(14354..16906)
                     /locus_tag="ACIZE9_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HGC6092523.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(17020..18351)
                     /locus_tag="ACIZE9_000634"
     CDS             complement(17020..18351)
                     /locus_tag="ACIZE9_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6092524.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(18317..19795)
                     /locus_tag="ACIZE9_000635"
     CDS             complement(18317..19795)
                     /locus_tag="ACIZE9_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6092525.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(20100..21935)
                     /gene="tdc"
                     /locus_tag="ACIZE9_000636"
     CDS             complement(20100..21935)
                     /gene="tdc"
                     /locus_tag="ACIZE9_000636"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HGC6092526.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            22405..23832
                     /locus_tag="ACIZE9_000637"
     CDS             22405..23832
                     /locus_tag="ACIZE9_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092527.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(23924..24289)
                     /locus_tag="ACIZE9_000638"
     CDS             complement(23924..24289)
                     /locus_tag="ACIZE9_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HGC6092528.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(24286..24651)
                     /locus_tag="ACIZE9_000639"
     CDS             complement(24286..24651)
                     /locus_tag="ACIZE9_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HGC6092529.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(24843..25091)
                     /locus_tag="ACIZE9_000640"
     CDS             complement(24843..25091)
                     /locus_tag="ACIZE9_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092530.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            25090..25218
                     /locus_tag="ACIZE9_000641"
     CDS             25090..25218
                     /locus_tag="ACIZE9_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HGC6092531.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            25275..26969
                     /locus_tag="ACIZE9_000642"
     CDS             25275..26969
                     /locus_tag="ACIZE9_000642"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HGC6092532.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            27069..27242
                     /locus_tag="ACIZE9_000643"
     CDS             27069..27242
                     /locus_tag="ACIZE9_000643"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092533.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            27620..28753
                     /locus_tag="ACIZE9_000644"
     CDS             27620..28753
                     /locus_tag="ACIZE9_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HGC6092534.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            28784..29104
                     /locus_tag="ACIZE9_000645"
     CDS             28784..29104
                     /locus_tag="ACIZE9_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HGC6092535.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(29133..29597)
                     /locus_tag="ACIZE9_000646"
     CDS             complement(29133..29597)
                     /locus_tag="ACIZE9_000646"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6092536.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(29729..30982)
                     /locus_tag="ACIZE9_000647"
     CDS             complement(29729..30982)
                     /locus_tag="ACIZE9_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC6092537.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(31011..31328)
                     /locus_tag="ACIZE9_000648"
     CDS             complement(31011..31328)
                     /locus_tag="ACIZE9_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGC6092538.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(31354..31674)
                     /locus_tag="ACIZE9_000649"
     CDS             complement(31354..31674)
                     /locus_tag="ACIZE9_000649"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6092539.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(32138..33553)
                     /locus_tag="ACIZE9_000650"
     CDS             complement(32138..33553)
                     /locus_tag="ACIZE9_000650"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6092540.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(33570..34886)
                     /locus_tag="ACIZE9_000651"
     CDS             complement(33570..34886)
                     /locus_tag="ACIZE9_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6092541.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(35036..35734)
                     /locus_tag="ACIZE9_000652"
     CDS             complement(35036..35734)
                     /locus_tag="ACIZE9_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HGC6092542.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(36023..37012)
                     /locus_tag="ACIZE9_000653"
     CDS             complement(36023..37012)
                     /locus_tag="ACIZE9_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGC6092543.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(37092..37925)
                     /gene="msrA"
                     /locus_tag="ACIZE9_000654"
     CDS             complement(37092..37925)
                     /gene="msrA"
                     /locus_tag="ACIZE9_000654"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HGC6092544.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(38100..39734)
                     /locus_tag="ACIZE9_000655"
     CDS             complement(38100..39734)
                     /locus_tag="ACIZE9_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyl-tetrahydropterin synthase-related
                     protein"
                     /protein_id="HGC6092545.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(39721..41409)
                     /locus_tag="ACIZE9_000656"
     CDS             complement(39721..41409)
                     /locus_tag="ACIZE9_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092546.1"
                     /translation="MKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLSRI
                     KGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLLNI
                     CTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYY
                     AYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFV
                     VVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDI
                     TTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLL
                     QFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVI
                     QSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKA
                     ADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIE
                     ITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            41555..43192
                     /locus_tag="ACIZE9_000657"
     CDS             41555..43192
                     /locus_tag="ACIZE9_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092547.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(43337..44077)
                     /gene="truA"
                     /locus_tag="ACIZE9_000658"
     CDS             complement(43337..44077)
                     /gene="truA"
                     /locus_tag="ACIZE9_000658"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGC6092548.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(44268..44903)
                     /locus_tag="ACIZE9_000659"
     CDS             complement(44268..44903)
                     /locus_tag="ACIZE9_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HGC6092549.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(45050..46270)
                     /gene="sstT"
                     /locus_tag="ACIZE9_000660"
     CDS             complement(45050..46270)
                     /gene="sstT"
                     /locus_tag="ACIZE9_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HGC6092550.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSESTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            46489..47487
                     /locus_tag="ACIZE9_000661"
     CDS             46489..47487
                     /locus_tag="ACIZE9_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092551.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            47683..49518
                     /locus_tag="ACIZE9_000662"
     CDS             47683..49518
                     /locus_tag="ACIZE9_000662"
                     /inference="COORDINATES: protein motif:HMM:NF013080.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HGC6092552.1"
                     /translation="MQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFFFLL
                     LLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVSPVL
                     LIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHKNSP
                     SFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMKKYN
                     TKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTGGLM
                     LSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIAIHP
                     FTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQSNT
                     ETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAVKKF
                     IQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAATLNK
                     EVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVFVTE
                     DSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(49578..50294)
                     /locus_tag="ACIZE9_000663"
     CDS             complement(49578..50294)
                     /locus_tag="ACIZE9_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HGC6092553.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(50521..51063)
                     /locus_tag="ACIZE9_000664"
     CDS             complement(50521..51063)
                     /locus_tag="ACIZE9_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HGC6092554.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(51068..51295)
                     /locus_tag="ACIZE9_000665"
     CDS             complement(51068..51295)
                     /locus_tag="ACIZE9_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HGC6092555.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(51374..53254)
                     /locus_tag="ACIZE9_000666"
     CDS             complement(51374..53254)
                     /locus_tag="ACIZE9_000666"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC6092556.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(53443..54057)
                     /locus_tag="ACIZE9_000667"
     CDS             complement(53443..54057)
                     /locus_tag="ACIZE9_000667"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6092557.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            54199..54759
                     /locus_tag="ACIZE9_000668"
     CDS             54199..54759
                     /locus_tag="ACIZE9_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6092558.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(55064..55378)
                     /locus_tag="ACIZE9_000669"
                     /pseudo
     CDS             complement(55064..55378)
                     /locus_tag="ACIZE9_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(55632..57267)
                     /locus_tag="ACIZE9_000670"
                     /pseudo
     CDS             complement(55632..57267)
                     /locus_tag="ACIZE9_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(57706..58575)
                     /gene="scrK"
                     /locus_tag="ACIZE9_000671"
     CDS             complement(57706..58575)
                     /gene="scrK"
                     /locus_tag="ACIZE9_000671"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGC6092559.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(58595..59716)
                     /locus_tag="ACIZE9_000672"
     CDS             complement(58595..59716)
                     /locus_tag="ACIZE9_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HGC6092560.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(59718..60113)
                     /locus_tag="ACIZE9_000673"
     CDS             complement(59718..60113)
                     /locus_tag="ACIZE9_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6092561.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(60132..60929)
                     /locus_tag="ACIZE9_000674"
     CDS             complement(60132..60929)
                     /locus_tag="ACIZE9_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC6092562.1"
                     /translation="MSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALSPIL
                     RKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKVGTM
                     GPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEFGYK
                     QGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQPMLD
                     KILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(60931..61719)
                     /locus_tag="ACIZE9_000675"
     CDS             complement(60931..61719)
                     /locus_tag="ACIZE9_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGC6092563.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(61733..62209)
                     /locus_tag="ACIZE9_000676"
     CDS             complement(61733..62209)
                     /locus_tag="ACIZE9_000676"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6092564.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(62281..64938)
                     /locus_tag="ACIZE9_000677"
     CDS             complement(62281..64938)
                     /locus_tag="ACIZE9_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC6092565.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKR
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(65002..65361)
                     /locus_tag="ACIZE9_000678"
                     /pseudo
     CDS             complement(65002..65361)
                     /locus_tag="ACIZE9_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
     gene            complement(65539..65859)
                     /locus_tag="ACIZE9_000679"
                     /pseudo
     CDS             complement(65539..65859)
                     /locus_tag="ACIZE9_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(65975..66496)
                     /locus_tag="ACIZE9_000680"
     CDS             complement(65975..66496)
                     /locus_tag="ACIZE9_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092566.1"
                     /translation="MDKPFLDSVREYLSNPKSTLFPHEDYKIIMNYYLPIGAPQNSKI
                     KIPNDIVNDGDTHNVIKGFLPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGL
                     DLKNLLCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLM
                     ELKKYSNTQTKFS"
BASE COUNT        20640 a        13456 c        10828 g        21976 t
ORIGIN      
        1 ttttaccctc ttttcttttt gtatttagat aactccctta tcttgcagaa ctggggtgat
       61 tttttcttca atttcatttt ttgaaacaat atttttcaaa tagatcatcg ccgttttagg
      121 atcaactgcg aacttttcga actgcgaacg aaaattttct gctgtgatga tcacatctgg
      181 tttcatggaa actgcggaag aaatatcaca atggtccagt ttggcttcta ctcctaattt
      241 gttcaaaaca tcctcagcag acatctgtgc tgcaaaacta cttcctaaac ctgcaccgca
      301 tacgaataaa atgttcaatt tgttcatctt tgttctcccc cgtatcattt attatttctc
      361 aactactgaa aaaagcagtt gtttgaaatc ttcgatattt gtgcattcaa tcaatcgatc
      421 caacttctct tcgttgttga tcaattcaat tagttctttc atgatgttca gatgcgagta
      481 ggagtctact gctgccaaac aaaaaataat ctttactgga tccatttcag gattaccgaa
      541 atcgattggt tgctcaatcg tagctacgct gactcctaat ttattgaccc catcttctgg
      601 tcgggcatgg gctagtgcca tgtgtttgcc aatcacgata tacggtccgt aatcattcac
      661 tgcacgaatc atcgcttcga catagcgctc ttcgacaatg ttttctttaa ccaatggtct
      721 agcagctagt tcaatcgatt cctcccaagt agtggctttt tctttgatca tgatattgct
      781 gtccgtcaaa atatctttta acataggctg gatctccctt ttgttgattt ctaaattgtt
      841 tgtttcgaat aatttttcta acttgccata gatgattcga tctactcggc caccactttc
      901 tttcatgaca tctattattt gagtgaataa ctccgtcgat tcatgactgt taggctctaa
      961 ccgctgtagt tcttcatttc ttttcaaaaa gtcttctata accaagatat tcgtctcagt
     1021 taaaatcgga tcgacaacta aaagcggctt atttcgataa ttcaattgaa aggtgctgaa
     1081 aaccagattg acatccaatt tatctactaa ttcgatttct tttgaactta aaactgcagt
     1141 aatctcgatc tgaggaaact tttctttcag attctctgct aacagatttc cagtagccat
     1201 cccatggtta cagacaacga ctgatttata aacataattc aagtctcgct tgattacact
     1261 ggcgatcgtc gaaaagtgga tgacaagaaa agctatctcg tcctccagta tcttgccacc
     1321 aattacttct tcgatcgtag gaacaaaatg agtgactgcg cggtagattg ggaaataatt
     1381 tgttcggatg ttttctttca atggattcat gacttggata tgattcttga ttcttacaat
     1441 cagtgcagcc atgtgcttat agagattttc gaataaagct tcttccttta gatggaaagg
     1501 tacgtgtgtc tcgttctcta caaattggat caattggatc gttagtaatt gagcttgtac
     1561 ccactcgatt gaattggaga tatctctagc attgaacgtc tcaatagtga aacgaagata
     1621 atttctttct acttgcggga cattgtccaa ttgaaattcc tcgatcatgt ggtcaataaa
     1681 tgcagaaaag ctactgtctt ttatttctgt atttttccaa ttaatggcag agataaattc
     1741 atgtttcctg attcgctgga tccagatcaa tgtaaaaagc aggatttgtt ttttataaat
     1801 atcatcttct tgtttcaaca acttattgga atagatctcc tgtatttttt tgatttccac
     1861 caaaggaaaa taatggagaa agattttttg agccggtgtt aattgtgcat cttgattcat
     1921 aaagaagtcg gtcattccca gattctgatt gataaaatca tagatcatcg tacggataga
     1981 tcgttctgaa cctttataaa ccagtccttg ctttccataa ctgacgatct ctatcccata
     2041 actgaccagt gttgctcgta accgtctcat atcttcatct aatgtacttt tagagatttg
     2101 aaattcttct tcttttttgt ttagatggat cgggattcgg ctgtaagcaa cggctaaaac
     2161 tagatcaaaa atacgttcgc gccgattcaa aaagccgtct ttcacatctt ttatttcagt
     2221 ttctaatcga gcttgctttt ccttttccag cttcaacaaa aaacctttgt tgcgaattgt
     2281 acggatctcc ggaagctttt tactgctcaa ccagatattc gcttcaagaa cttcctgacg
     2341 gatcgtccgc tgactgacat tgaactcact tgctagatgt tttgctttta ctggatattg
     2401 ggctgtcatg attctgtgaa gtatttcaat tgttcttgtt ttcatagaaa tgatctcctt
     2461 ctgatttcaa gtatatggtt ccgcttacat aataaaaagt agatatttct gccacttgaa
     2521 gtggaaagaa agtaagcaaa gcaaacaaaa aataagccat atgctttttc atctcctcaa
     2581 cgaaaaagac atacgcctat tattacaaaa attttgccca tctatacaaa aaagaggttg
     2641 tgaaaaagct gtcctgcatc aagtaataag aacaactaaa ctaaaatagt gcttcctatt
     2701 tttcgtttgg ttgttcttat tatcgcagat gcaagctttt aaacaccatt tagtggagag
     2761 gttgtgacag agatgttcag ccttgagcga taagaagcga ttttgaaaaa tcgcttccca
     2821 tattttacaa aatcgtgcct tattgccgat aggctatctc tggcacaccg tttattcaga
     2881 aaaaggagct gcgacaaggc ttttgtcaca actccgttca taaatatttc ctgtcaatcc
     2941 agcataatcg gctgaataaa atcggcttgc catctttttt ctttctcaga aaaatcaaaa
     3001 taccatatct gagaaaaata ctgtcgttgt gtcttacttc ctgagatcaa tcgcccatct
     3061 tttcgatcga ctgaataatc acagcatctg aaatcaattc ggatggcaaa actattttcg
     3121 tggatctgtc gataatttcc tacttcctga atagttattt ttttagtatg atttcttaca
     3181 ccgtctgctt tgtttttttg cagaactttc tgatgttcgg caaacagctt gtctgtataa
     3241 cagcttctgg ctttttcagg agtttcttct tcccaagcgg attggatctt catgaatatc
     3301 ttttggattt ccagaaactg tgctttcttt tctttagccg ttcctgacat gcgggacaat
     3361 atctccgctt tcagcctttt cttttgtctt ttattcttga cgatagaaaa agcagaaacc
     3421 cctcctactg acaaaacagc taatgcaaga aatcccgttt gctcataact agaaggacct
     3481 gtacctggac cataataccc ataagaatct ctgccgtaag aacgactgcc aaaataactg
     3541 cccccatatg aacgaccacc aaatgaacct ctgcccgaac ttcgaccgct agatgtacct
     3601 ccaccatgac cacccgcgac agcgaatcct tgggtcggca gagcaaacaa acataggccc
     3661 actaacaaaa tgattgctaa ataattgatt tttttcattg tcttcctcgt tatcttttat
     3721 tacaaaaaac tatttttatg atagccttgc taaaaggaag agtcaataac cagatgcata
     3781 aactgttttt ttagcaattt tgtcttattt agtcattgag taacatcgga caaatgtatg
     3841 tgtcggcagt ccataattcc tctatcttca gcatgaacaa gcttgcagac aagagatctg
     3901 cgcttcctcc aggagagatt tggttttcct gacaaaagtg caacagtgct gtaaatggac
     3961 gatttggtaa agcactttga ctagcagcat gagcaagttt ttgcatttcc actaacgttt
     4021 tctgatcact gcgatgcaat acgcatgtgt catctagcga actcatcaaa actaacaaca
     4081 tatgcatttg tttctgtaca tatgaatcat tatctagctc cttagctgct tgaattgcaa
     4141 gcctgatatg cggataccct aatatcgctt cttcatatgc accatttacg ccatattttt
     4201 gcttcaccct atgaccatga gtggtttttt tatgacgata ttttgtatca ggaaaagcag
     4261 caagcttgct gacatcatca agtattttcg ataaagaaaa aggctgttcc atactgattt
     4321 tttgtgcaat gacactgatc aatagcccca ttgcccaaat cgctccttta tgggtattga
     4381 tgccatttgt agcaatcagc attgcctttt ccgcttttcg cccaatctca gcaattcttt
     4441 ctcttaactc ctgatcaata gcatgatgcc atgctatttg agccatttct tcaaaaaaag
     4501 gagttagcgt cttagcagac ttaagaaata aagcatagtc catatcggaa tgtgcacccg
     4561 catccagtgc atccactaat ccaggttttg gacttaatgt tacttctgcg atcaatgctt
     4621 cctctaccaa cgcagcgagt tgctgagtca ctgctttttt tcgttcgtca tttatcatga
     4681 cactcactcc ttcttcctac tattacttgc tgaaaccttt tttgatagct acccaaatga
     4741 tatgaagtaa ccagcttaaa gcaaatgcac aacttgccgt cattagataa gctacaagaa
     4801 tcatgactcc tgaaggtaac tgcagccaac tatctttaaa caataataac agtacttgga
     4861 aaacaaatac attggctaaa tacgtacgat aagcataaac agacaaccat ttgaacaatg
     4921 gcaattttgg cgaatcgttt acaatcattt tggaagcgcc tatgaagaca gcaaagatga
     4981 tgactaaact gtataaactt tggatcgtat tcaagtaagg tgcattcgca aagctcaagt
     5041 ctcctggatg tgcgagcaat gaacggacag aaaagaacgc gataactaag gcaacaggta
     5101 agaaaagata acgtactctg tccaaatatt gatagacttt ttcgtgataa acaaatgcgg
     5161 ctaccccata aatcatgaaa ctagcaacaa accgatctaa taagtaccag ctgtcatgat
     5221 aaggcccagt caatacttgt gtttgataga acagatacca tgcgacatat aaaatcgttg
     5281 aaccaatcaa tactggccat acatattttt tattagcaaa tactttgtaa ccgagccaaa
     5341 caaaaaacgg catgaacaat tggatctgca gcatcataac ggtataccat aaatgaggcg
     5401 ctccatcacc tgtgacatat ttcagtaaaa agcttgcagt atccgtatac ggagtttgtt
     5461 gttggactgc tggaaatagc caaagataag ccgtcgtcca tagaagatac ggaacgacta
     5521 gttcaaaaaa cttttctttc aaaaattccc aataagacaa atgctgactt gtttttacca
     5581 tattataaac aattgcaaaa ataaacattg gtgctgtgta tttaacgatg acgtaaaagg
     5641 taccaagaaa agctgtattt gttgcgctgt ggctgtttgc caaagcaaag ctcaatatcg
     5701 tttgcatcat aacagccgtt acagctgata ctttctggaa gtcacttacg ttgattttga
     5761 tttttttgtt ttcaaacatc tctttctctc tctttttctt tattaccaaa gttctttggt
     5821 taatttaggt ccttcgactg ttttcaatag aatttttttc tctggctctc tcaaatactc
     5881 ttttagtgaa aaaccgcctt gccgagtcac tacttgggta tcgaattgct caaaaaaagc
     5941 aggatgcgat tgaattacct gaattggcaa ttcaatcggt gaatttgcgt acagcagcaa
     6001 atcaaaatca ctggtttctt ttactgccgg aatcccagtc gataattcaa atcctaagct
     6061 gccgccgatt ccccatttac atcctgataa tatgtttcta gcagcatgaa attgctgata
     6121 aacaggataa tccatgattt tctcttgtct atacgattct tgttcgatga tgtcccacgg
     6181 atgaatgact tgtttgacgg catgttttga gatttctgtt gaccatctct gattgcgggc
     6241 aggtccacgt aaaccaatcg gtagtatttc tgcgtgatcc gtcgacgcac gacgaactgt
     6301 tccgaacatc ttttcagtta gaacgaccca ttcaggcaag gtgaaccctt ctatttcatg
     6361 tttatcaaaa aggacaatat catgtgcttg aatcattttt tatgcatccc attcttcgtc
     6421 cattttggca cggactttat ttgtttcgac acgtccgaat gttttggctg tttcgtttgt
     6481 gtatcgattt gtcagcatcg tgtcatttgt attgcggaca tcttgaatgg cttcattgat
     6541 tgcttcgatg actttgctga cattttgttc tgaagcagct tggtcggtga tatcttctag
     6601 gaaatgatag atcgctccta gttttgtata attattgata tcgtaagcga tagctggaac
     6661 tttttcagca gctgcttcga tttcagcaac cgaacgtttt gtcacacgtg cagcactttc
     6721 tttagacatc gcttggacgg taatttcttt attgtttaaa gcaatcaagc ggcttgattg
     6781 taatccatgt gctaaaaatg cacctgaaat agcatttcct gcaatcaatc caataactgg
     6841 atgtccagct tgacggagtt ttgcataagc agcagcacta ttagccaaag ccacatggat
     6901 accgatcaat tcttcgttat agccgtatgc ttggcttggt acatcgatca caacgatgat
     6961 tggccgtttc acttttttgt ctttatcttc ttcgtaaacg tgatccaaaa tttgtcccat
     7021 gcggaaacct tcaactaaac caacttcacc gtttcgtaca cggtacatcg ggtttttagg
     7081 atcaggtacg attgatgtca cgatggcttc ttctatgaat ttacttgatt taccataata
     7141 cacagtacta atagaagaag ttggattttt catgccagtt agtgccgcaa accaatcgta
     7201 accaacactt gctgcagctg gttcatttcc ttctgctact tctggtaagt caattgattt
     7261 tgcttgatgg ttagcaattg cttcattgta atcgtcaatg gccattggtt ttgaaagatc
     7321 taaagaatca agtaatgata aataaaatgc tgagctttca ctgcgatgcg tgtcttttcg
     7381 ttcgtccatt gctgcgatga cagcagcttt gattgcttct acactatcag tcactaattc
     7441 atcaatgatt tttgattcta cccgttgacg agatcctaat gtattccaaa tcaagtcttt
     7501 gtcactagaa tcaaattctc gaacgcctgc ttcttgttca ataacttctg gtccattcaa
     7561 accgactctc gctttttttg ttgcgattaa ataactcatt aatgctgaag taatcgacat
     7621 accgccaaat gatcctacac gtcctggaat caaaccgatg actggtacat attgttttag
     7681 agcaatgatt acatttccga tttctgaaat agataacagt ccgtagtttg cttcttgcaa
     7741 acgaacacca cctgtatcta gtacaatgac tggaaagatc tcatttcctt ttttattttc
     7801 ttctaacaca tgttcaagtg cagcaacgat ttttgcaccg gaaacttcac cgataccgcc
     7861 accttggaat tttccttcca tagcgattac tactgcttgt ttgccattga tcgtgccacg
     7921 gctgacaacg atcccgtcat cactttcagg gacgattcct tgtgctggta aacttggcgc
     7981 gatgatttga tcgaatggat caatcaattc acgtccattg tcaagtagag cgttcactcg
     8041 ttctctggcg tttaattcta caaaactatt tttcatctga aagttcctcc attgcttgcg
     8101 tcaatcgtag gtacacaact cctggtgtag caccgaagtc attgatcacg atatctgctg
     8161 aaattggata acgatcaaaa aatctcgtta atacattgtt ccatacttcg ccgaagccat
     8221 cgcttcctgt acaaattttt acagtagatt ctgttttttc tgttggaaac atcaagattt
     8281 ccaaatctcc tgaaccgacc actcctacat ggattttctt attgatcggc tgtttcgttg
     8341 gatatttata agctaattgt tccatggatc tctccccttt ttgtaaaaca gagcatacac
     8401 gttctgctta ttcgtctttc ttcttccatc tgggtaaatg gcgacaaaag gtttttctcg
     8461 ccaattttat gaccaagttc tgaatttcat tggtggttca tacaggccat ctgaccattc
     8521 gatcaaatca tcgatggttt gtgcagctaa taatgaacgt ttcgcttcac tacgtttgat
     8581 gcctagatct tctggtaatt tcacgatgcc ggctgcacgc aagctatcta gtgattcttt
     8641 cgtgctagtc attccaagag gtgtaacacc gccaattgct gcaattgctg cttgtcgttc
     8701 ttcttttgtt tttgctttgt acaaataagc aattccttct tctgtcacga tatgtgtagt
     8761 atcttcgcta taaatcatca ctggtgcatt gcattggcta agcctgcttg tttttgaaca
     8821 gctagtgcat ctaattcttc gacaaagact ggttttttat ttgaaccata tgtttcaacc
     8881 atttgaacaa ctaatttttg gcctttccct aatggatcat cattgtcgcg aagtgattgc
     8941 catgctggtg tagaatgacg acgaccgcca ggattatgtc ccatgttagg cgcaccgcca
     9001 aaaccagata aacgtccttt tgttacggta gaagagtttc cttcgtaatc taattgcaag
     9061 gttgaaccga taaacatatc gatggcatat tgtcctgcag cttgtgataa tgttcggtta
     9121 ctgcgcatcg tgccgtcttt accgacaaaa aagacatctg ggcgagcagc aatatatttt
     9181 tccataccaa cttcgccacc aaaactatgg atgctttcaa cccaacctga ttcgatggct
     9241 ggaatcatcg ttggatgtgg gttcaatacc cagttcttcg cgattttccc ttttaaccct
     9301 agtgattcac cataagttgg cagtaacaat tcgatagctg ctgtattgaa tccaataccg
     9361 tgattcaaag attgtacgcc gtgttctgcg tagattcctt tgattgccat cattgccatt
     9421 agaatttgca attctgtgat gttttgagga tctcgtgtga ataaagcttc taattgataa
     9481 ggtttatctg ctttcacgac aacgtctacc cagtcaccag ggatatctac acgtggtaaa
     9541 gaatcgacaa cttcgttaac ttgaacgatc acgataccat ctttgaaagc tgcagcttcg
     9601 atgattgttg gtgtttcttc cgtattgaaa cctgtgtaca agttgccgtc tttatctgct
     9661 ttatctgcag ctactaaaac aacatttgga atcaaatcga tgaataagcg tccataaagt
     9721 tccaaataag tatggatatc acctaatttc attgtgccgt cttcaatcat ttgggcgaca
     9781 cgcaagcttt gtgcaccagc ataagagaaa tcgatcttgc ttgcgattcc tttttcaaaa
     9841 atattcaaat gttctggtcg tgagatacta gacatgatca aatgcagatc attcactttt
     9901 tctgcatcta ctttttcaag actttctgaa agaaaacttg cttgtttttg attgtcgcct
     9961 tctaatacaa ctttgtcgcc gggagcaatc agtttttcca ttacttctac gattttttca
    10021 gtttctacat acttgccatt gagcaagttg ctgatttttt ccaatcgctg cgcttttttt
    10081 tcgcgtttag aagcccagtt gcggtttggt ttttccataa ttagtcatct ccatttttga
    10141 tatagaaacg tggcgtcatc aataccatgt tggtctagat tgatcgtacg gatcccttta
    10201 tctacaccaa attttgtatg aatcagcttt gtcaaagtat tgccgggggg aaattcaatc
    10261 gtcagatcca ttcctaattc ttttgccaag tccatcattt ggttccactg cacagggaaa
    10321 gctaggtttt ccaacaaatc tttacgaatc tcttctgcgt cctgagtggc tcttccatcc
    10381 gtatttttta tatacaaaca tctagcatca gatagatgga cagactgcat atacggcttg
    10441 aatttcttga ccgtatcatt catcaagaga cagtgagatg gcacagggac tttcagcagc
    10501 ttcgctgttt gcgcttggtg ccgtttggct tctgccaacg taacggataa accttcgata
    10561 ctcccagata acgtatgttg catcggacaa ttttcatttg acagataaac tggatggtca
    10621 ggatcaaatg tttttgctac aatttcctca gcttcgcttc tcgtcacacc tactactacg
    10681 cccattgcat aaccgcttgg ataagcttct ttcattaaga ctgcgcggtg atagactagt
    10741 tccgctgcat tctcaaatct caaagatcga caagcaacag ctgcacaaaa agcaccaatc
    10801 gaatgtcctg ctgcaatatc aggctgaata ccgttttttt ccatttcatc taaataaaat
    10861 actgcttttg tcagtaatgc tagctggata aaaaccgtat cttgatagtt ttcttcttta
    10921 tcaactaacc gataccccgt cacattttct aaacgttcca tgtacatttc agggatatcc
    10981 gctaacatcc ctaacttctg actgccttgt ccaggaaata agaaacctgt actcatgagc
    11041 ctcgcctcct cagcacttac tttttccact gctatcttag tcaatttctg ctataataaa
    11101 aaatgccaaa aaaagaaaaa accataacaa aaaggtatgg atgggatgga taattatgaa
    11161 attgcttcat ctgcagtatt ttaaaaaagt attcgaaaca aaaaatgtta cccaagcagc
    11221 caaagaatta tttatttctc aacctgcctt gagccgtgcg atcaaacatt tggaaaacga
    11281 attaggtgtc cctttgtttt accatagcgg cagaaacatt gagacgaccg tttatgcaga
    11341 agaattttat ccatatgcag tcaagacatt agacacatta gaagaaggaa tcaaattatt
    11401 gtcttcggtc aatgagaaga tcgttacttc cgtcatattg tatttagagg tagcctctgt
    11461 ttctattccg aacttggtcc gaatttttat ggaaaagcat cctgatatcc aattaacgat
    11521 catgcaacat catttaccag atgatattac cgatcctgta ctgtacatca cttcggagat
    11581 gaagcctggc atgaccaata ttcctatcat gaaagaacct gtttatgtcg ccattcctaa
    11641 gaaacatcct cttgctaaaa aagaacatct gcaattagaa gatatccaac gcacccccat
    11701 cttgatgctg tcaaagagca acgccttccg tcatacactg gatgcagcac ttgaagcgaa
    11761 aagtatcgaa ttgacgatca gttcgacgac agatgatcct gcgacattac gttctattgt
    11821 caagcaagga ttagctgtta gctttttccc aaaagtttct tggtcttacg ataaaaatga
    11881 tcctttcgtc ttgcgggaaa tcaaagattt gcccttgaca cgaacaattt atttatcttc
    11941 tagcttcaca gaagatcatc ctttgatcaa aatgattgca aaaacgatgc gggaatttta
    12001 tttaggaaaa taaaaaaaaa agagctggga caaaattctt gtcgcagctc ttttttcgaa
    12061 caaacggtgt tccagaagta atttcttaga aaataagccg aaatttccca aaaatttgag
    12121 aagcaatttt cgtaaattcc ttcttatttc ttgaagctaa acatttctgt cacaacctct
    12181 tctctattgt cctagacatt cattgcgttg atttaaaact tccatcaatc aaatctgcta
    12241 gttcatctag cttttctatt ttacgtagat caatagagat ccaatgttct ttattcatgt
    12301 gataggctgg aaaatacccc tcttttcctc gcaaaattcc gccaagttca ggatcgacct
    12361 tcaaatcaag aatattgatg atcctatggt cacttgcatc atcatagatt ttttcttctg
    12421 gaacagacat caggacccca aaccattttt tgcttttttg atgtctgaat acgcaataat
    12481 caggaaattt tttaaaaata tattctggag acaaattgta tgtttcattg atgtgatcga
    12541 ttagttcttt tttcgttagc atctgcttcc atctctttct tattgattcg ctttattcaa
    12601 agataccacg taagaataga aaaatgaata caagtagttg ctaatcaaat acttcgatat
    12661 ttttcttttt tatcaactct taaatgttca atccgcctgt gttggtcttg ctaccatcta
    12721 ctattaaaat gtttattatt gtttgcccac ctattttttg attttagtgg tatcattttt
    12781 caagttcatg atgaaattct tatcatcagt aaatgctcca gaaaaataaa caatgattga
    12841 aaaatcagtt gaaacttgac caccgtttat tttctccgta ttcttagaat agaagggagt
    12901 ctgattgatg tattcactaa tgaaaaaaat cattaccgaa aaagatattc gacgtcatgt
    12961 ttctttagta gaacaattgc tgaatcatac aaagataacc gtaaatgaat tagctgaaat
    13021 catagggaca accgaacgaa cgattttttc tgaccttcaa tctattcgct ctcagctgcc
    13081 cgaaggctgg gacatcatca gcgatcaagc aggaatcagt ttgcaaaacc agcaaaattt
    13141 attaacaaat gacctttggg agattttttt caaacaatca gtcagtgtcg aactgctgaa
    13201 aaatctgctt tttacaaaaa aagttgctgt ccctgatttt ctagccgacc atgggctttc
    13261 ttatgggaca ttgaaaagac atgtgactaa aatcaatcag cgtttagcaa gttacgactt
    13321 gcagatcgat ttgacgaaat atacagcttg tattcttgga aaagagcgtg cgattcgtac
    13381 tttttatcat cgattgctga ttcctttcac tcataacaac tattttttcg aggattattc
    13441 gatccatgaa tcccattatt ttcaattttt aagaaacctc agtcaaactg aactagcggt
    13501 tgaaacagaa gagattttcg gaacatgttg gttctttatc aatacgatcc gtataaaagc
    13561 gaattgccga ttagattctt ctatccatac caacagcaca ctctcctccc tgtatgactc
    13621 tgcattgaaa aaattgtatt taacggaagg tatttatctt aaagacactg agctttcttt
    13681 tgcttctttc tgctttctgg aaagttggaa ttacaacaat aactatggac aagaaaccgc
    13741 tcgctgcctg catcattctc catttttaga ggtcctcgaa acgtttgtag aggaactagc
    13801 ttcagagctg tctcttgatc aactaaaaaa aacatctctg actgataact tggctctcct
    13861 catattaaaa tatcatgaat cgccgatatt gattgaagca ttggaccgtc aataccatcg
    13921 ttttttagaa acatatgatc agcaatatgc acacttgtat caacagaaag agaatttact
    13981 gaacgatcta aaaaaagaaa tagaaatcaa tgaaccaaat tactttctcc aactcttgtc
    14041 tctactgatc caacaaacga ttttttctat caaaccgaat ttgttcaatg tctattttat
    14101 tttccaagga gaaccttcat ggaaggcgtt cttgcagcag gaattaaaag attacttagg
    14161 aaaacgtgtc tgcttcttac ctatcgaact aaccgatctt tccactattt cttttgaaaa
    14221 aacagatatc ttgatttcca atttccctct agattctcta gatatcccta ttgtatacat
    14281 ttcttctatt ccaacgaaaa atgagctcaa tcgtttgact gaactcactt tcaaaacttt
    14341 tttatagtaa cggctagcga ctgtattctc tagctgtttt ttcttttttg cgaaacagtt
    14401 tgttcatgat ccctttttct atttctacaa ctaagaatag aagaatcaca tttgctccaa
    14461 tcaataactg ttgtgtcatc gttaaactta ctgtaccgat cagctgctgg ccgactggta
    14521 gaaaaataac catcccttgc aataaagcaa ggatacctaa tgaaagaaaa agcgctttgt
    14581 tttgcaaaag accttggttc aatgacggct tggacaactc tctgcaattg atcatgtaaa
    14641 cagcttgagc taagacgata ttttgcagaa gaatggtttg ctgtaagctt tgcccttcaa
    14701 actgcatagc caataaatag gcaggaacca tgatcagtag ggagacatag atgatccgaa
    14761 acaaatgata accagatagg attccttgct ttggatctct tggtgggcgc ttcatgattt
    14821 ctggatctgg cgactcgaac cctagtgcat aagataaagt gattgtcgtt accatattga
    14881 cccataaaat ctgtactggg gacaaaggta gcgggcgatt cagcataagt gcccaaatca
    14941 agatcaatcc ttgagctaat gcagttggca agaagaaatt gatggttttt tgcaaattat
    15001 ccaaaatccg ccggccctct tttacggctt ttgcaatcgt atggaaatta tcatctccta
    15061 aaaccatatc agctgcctgt ttgcttactt cactaccttt gattcccata gcaattccta
    15121 catcggatct tttcaaagca ggtgcatcat ttacgccgtc tccggtcatt ccgacgattt
    15181 ctccattttt ctgcaaagct ttaacaattc gcagtttatg ttctggtgtc gttcgagcaa
    15241 agacatcgac tattggcact tgctgaatca actcttcatc agacataaga tccaaatcga
    15301 tcccttctaa aactttggca gtatgtttta agccaatttg ttccgcaatc gcttttgctg
    15361 tgtctttgtg atcccctgta atcattttca ctgagatccc tgcttgttgg cattccttta
    15421 cagctttgac tgcactttct tttggcggat cgatcaatcc ggcgatccct gcaaaagtta
    15481 attgggttaa agtctcatgc gtgagttcct gtttcgaatc tactttttta taagcaaatc
    15541 ctaaaacacg ctgacctttt ctcgcaaatt ctgcagctgt ctgactccat gcttcttgtt
    15601 ctgcagaaga aagagttgat ttagcaaata atacttctgg tgcacctttg acgtaaatca
    15661 ccgctccttt ttcctccgca tgcatcgttg ccatatattt gtattcagaa ctgaacggaa
    15721 tctttgcttc tatttttttc aaaggtagat tggctgtttc tgtgtgtcga atcagcgcaa
    15781 cttctgtcgg attgccactt aaattttctg ttttctgttc ttcttttgtt tttaattcct
    15841 gacagttttt cataatggac aacacgcagg cttcttcttt tgcagctaca tccacaactg
    15901 tcatttcatt ttttgtcaat gttcctgtct tatctgaaca gatcactgtc atagaaccta
    15961 atgtttctac cgaaggaagt cctttgatga tcgccttttc ttttgccatt tcatgtactc
    16021 caacggatag aatcatggtc aaaacagctg gcaatccttc gggtaccatt gacaccacca
    16081 aagcaatcgt agccgaaaga aggatatgcc aatccatacc atatcgaaat gtcgtaaaaa
    16141 taactaagaa taggctcaaa caaagaatgc cttgaaaaat ttgtttgttt aatcggttga
    16201 tttttttaat cagaggcgtc gtttgttgtt cgaccgattg caatgcttga ttgattttac
    16261 cgatttctgt cgtgtttcct gtttctacaa cgacaccgac tgcagaacca gattgtacaa
    16321 gcgttcctga aaaacccata tttttctggt cgccgatcga ttcttcttct gtcaaaacgg
    16381 catgactttt ttcagatgct tctgattctc ccgtcaaaat cgattcttcc actaataaat
    16441 catgtgcttc gattaatcgg atatctgctg gaacgacatc tccggcacgt aagacaatga
    16501 catctccttt taccagttct ttcgcaggga ttttttcttg catcccgttt gatagtacta
    16561 tcgcttcttg tcccatcagc tgcttcaaac cattcaatga ttcttccgct tttctttctt
    16621 gccagtaact aacgagtcca ttgacgatca ctacgaataa aataatactt ccttcaatat
    16681 attcactaga agcaaatttc aaaaaagagg caatgatcaa cacgatcatc agcagatcag
    16741 taaaatgctt tgctattttt ttccatcgtt ttgtctgctg ccttgctttt atttcattat
    16801 atccttgatc agtcaggcgt ttctgtcgtt cttcttgcga caagccttct gttgatgttt
    16861 gatagttttt caatacatct tctaccgtca atctgtacca gttcatccta tcccctcctg
    16921 tttaattgat actgttatta tacgcaggga agttttttca ggcgtatcga ttatttcagg
    16981 ggggtctgaa ataattcgtt ttgcaaaatg tatctgggcc taactgatat ttctattgct
    17041 tattctttta tatacaaaat ttaagaatac aaaccagata accaataaaa aaggaataaa
    17101 gcgtgtcgtg ctttcgaata acaagctgaa agcaattgaa gtaaaaaaca ccaacaaagc
    17161 aagatcttta tatctttgtg tagtgttccg tttcttttct ttaataaatt gaacatgtgc
    17221 acacaagatc gaagaccaca caaatagaaa acaactcgtt gtcatgcctg ccaaaagctg
    17281 aaaaaacaat cgactatcag ctacaaaaaa atgtagacaa agaccggcaa aaaataacat
    17341 tcctgtaatt aaaataccgt gtaaaggtac gcctttctta gaaagcgcac aaaaccaatg
    17401 gggcaaactt ttttcttttg ctgtttgata taaaatcctg ctagtactgt agactgcact
    17461 atttgctgag gacaaagaag caaccaaaat cattagattg acaattgctg ctccgccttg
    17521 gcaatggatc acttgcagca tagtcactaa aggactttct tttaaatcta aacaatgcca
    17581 tggaacaaca aataaaatcg acaaaatcgt tcctatatag aaaaagagaa tacgccaagg
    17641 cagacagttg attgcttttt tcaaattctt ttgcggatca cttgtctcgc caacggttaa
    17701 gccgatcatt tcaattccag caaaactgaa taaaaccata ggaaatgaga ctaccattcc
    17761 agcaaagcca aacggtagta attcatcgat ctgtccaaaa ttttctttga ttccgataga
    17821 ctgggtatga aaatctgaga cactcaatcc tatacccaat aagataaaaa ggaaaatccc
    17881 caagatcttg atgattgaga aaaaagattc caattcacca aaccacttga ctgcaacaag
    17941 gttgactgcc attaagatca ttagtgcgct acctccgctt atcaaagctg gtacatgtac
    18001 aaaccagaaa tggatataca atcctattgc tgttaattcc gcaagtccag ctccaagcca
    18061 gcaaagccaa taagtccaat tgacaaaaaa tgcccacttt ttgcctaaat aatagtcaac
    18121 gaaatcactg atagagttaa atgtactatt tgctaaaaat aaatcaccca tggcccgcat
    18181 caaaccataa atagccaaac cgcatatcaa ataaacgaga ataacagctg gccctgctga
    18241 tgcaattgcc tttgctgaac ctaaaaataa tcctgttcca attgcgccac ctaatgcgat
    18301 taactggata tttcgattag ttagagtccg tttcattgcc ggtttttcca tcaagttcac
    18361 ctttttcttt ttcaagcagc atggcgactt cctgttccca agaaggtttc tttatttttt
    18421 caatacagag tggtactaca aacaaaatga cactgatggc tgtgactgca attagattga
    18481 tccatgttcc agctttcatc gtcagtccga cagaaaatcc gattgccgca aataaaacaa
    18541 taacgacagt ccaaactcca agattgctct ttttctcttt ttttccaatt ctaaatggtc
    18601 gattcaactt tgcatgtgta taacgcaatc tcaaaactgc gatccccatg atgacataga
    18661 cgatacagta gataacagta gttgaattta cgagcatcaa aaatgcttga ttgacgccag
    18721 gaatcagcaa ataaaaaagt gcaaagattg agataatgac agactgagtc aaaataacgg
    18781 atttggatac gtcaaattga ttcgtcttcc aaaaattgaa ttttggtgga tacgcacctt
    18841 ttctagcact ttctgtcact gtctttgctg gtcctgaggc ccaagcagat aattggactg
    18901 ctacaccaat gaagacaagt aaactaaaca gattcacaat aagatgtggc aaaccaagaa
    18961 tttggcaata aatcgaaata gattgcgcga tattattcaa ttccatttgt ccttttggta
    19021 cgacatttgc tacaactaaa gcattcaaaa tattgacgaa aaatataaaa attaacgcgg
    19081 caaatactcc gcgaatatac gttttaactg gattttccaa tcgagtgata tacacagagg
    19141 acatttcgat accagtaaaa ataaacatga tcggcgcaaa ataaacaaat gaggatgcag
    19201 tcgtagtatc tggtattaat ttgtcccatg aaaaactgcc taatgttccg gttggtacga
    19261 tcccaacttt gatccacgca gcaaacccta ataagagcat catcgtcaaa ggcacgtaca
    19321 atcctaacca aacaccgact tttccgccga tttttgccat atcaaatttc aaattcaaaa
    19381 aagtgatgat ccaataaacg actaaaatga caactaatgt aaatttgctg ttcaaaccaa
    19441 gcggcacatt atcgataata ttaccaaaca acggagcgag tgctgaagcg accatcacca
    19501 tcccaggaaa catttggacc cataacagcc atgagacaac gaacccccat ttttttccta
    19561 gagcattcga tacccaaagt tctggaccac ctttttgggg aaacattcca gcaaattcac
    19621 cagagatcaa tgagattgga aaagcgtaca ataatactgc aaccagcatg taaaaaatca
    19681 tcgtccagct cgttgctgct acatctggaa tatttcgtac acttgctaca agggcgcagg
    19741 tcattccgat aaaggtcatg gtcgtgattt gctttgatga accagtatct ttcatcttta
    19801 ttccttcttt caatagcgac atatgttttt gttttctttt atttttgttc aagaacagaa
    19861 atgacaaggt ttcatcgatt cagtacaaaa cccagtatca ccgaaacatc cattgaacga
    19921 tcttagtgaa ctgggtttga tacatgaaac gaacgatcca acttatagaa cgttttataa
    19981 aaaagaatat cttggcgagg aatatatgaa aaacaggggg aaatacaatt gttttgatga
    20041 agcaaataat tgtctgttct ccatatgtct cttgttattc tttcacacaa aaatcagttc
    20101 tattggatga tttcgtttag tttcttttcc attgctttgg cgattttttt tgtataaaaa
    20161 ttgaaaattc gatcatcatt caaataagga gtcatgatag ccgcacgtag cagagtgatt
    20221 ttctgttctt ttttccattc ttctttcgtt agacccattc tttcaacaaa acgaatcgga
    20281 gaatcaccgt aatcttcttg tgtaaatgta gtatgagaag taataaaccg ttcaccataa
    20341 acatcgccat ccatataaga agaccgatcg aacatttttt catttaattc attgatagcg
    20401 ttcaaatctg tacagccttg ttctttgaat acccaattga ccatattaaa atcaggatga
    20461 ttcaatggat agacttcgat tgtttttcct ttaacagtaa aagtcagatg atcgagaaat
    20521 tctctgaatc tttgagctgc ctcgattgaa gccccaatca attgaccata tccggtcaca
    20581 ttcaatggca atacacgatg tgctgtccag actgcggcgg cggttgctcc agcttttgat
    20641 ccttccaaaa tataagctcc taacatatct ggagccttta ctgatttttc aaacacatat
    20701 ggcgcgaaat aagaaatgat atttctcata tttttatgtt tgattacgat tcctccagca
    20761 gcataaggga catagcccat cttatgagga tctatcgtga cagaatccgc ttctgaaata
    20821 gctctgaacc cttcatatac ctctttgtca atcgttacgc agtggtggaa aacatgatgt
    20881 tcttcaaaga attcagctaa ggaagcatac ggcacaaatt ctcctgcttc gtttagaaac
    20941 agtgaacgcg catagccgcc atatgcggca tcaacatgta aatagaaata gatcccttca
    21001 tcttttaacc tttctcttaa ttggacgatt ttatctacac tgtctacttg accttcttct
    21061 gtcgttccta cgacagcaac cacacctaga attgggattt tttgtccagc taattcacga
    21121 attgtttttt ccaaagcatt aatatccatt cgataatcct cttgaactgg gatagcaacc
    21181 atctgatcta agccgactcc gcaaatatct aacgccttca tccaagaata gtgttttgtt
    21241 tgagggacca gccatttccc taatctttgg atattttttc cgctacggga agaagctgct
    21301 ttgacctcat ccatttcttc gtccgtaaag ctttcggtca tttccaaaat ttcttcaaca
    21361 gataaattca aaagttccca ctcagacatt tttttcactt tttcaggcag cacttccttg
    21421 acagctaaag gaatcgattt gatgcaacgg gcgtaccata atccttcaag attagcaata
    21481 gaaccatctg ctgcaatgtg tccccatccg tctgtcatat tgaataatga agcaaaatcc
    21541 tgtcctactt ctgcttccat ttgcgaagtt gccatagaag attccaatgc aacattattt
    21601 gggttccaca gcatcgcata gttgtaagct aataaagcag gcatcaatgt ttcagcattc
    21661 atttgtcccc agtaacggcc tgctgaatgc catgggatcg atcctgcgcg taatcgctga
    21721 ctgacttcat ccaagacctc tatcatatgg tcgcgggtgg ctagataatc tggagtgagc
    21781 ttatctcctt cgctaattgc aggcatatct gaaggaatat aattttctct ccatccaaga
    21841 tgttcatcta ccatcttgtt caacaacatt ttataaactg gtccattttc agctttgtcg
    21901 cctataaaga cggccttgat atccatatct ttcatttttc ttccctccat attttgttgg
    21961 tcaatgtctt gcagatacat gtgtttatct gtaacacctc ttcactatag cgccaaaaat
    22021 gagaattttt tttttataac atcaaatcca cgtagatttt tacaaacaaa aataaataaa
    22081 gtcggatttt tctgataatt caacgcaaaa aagcgaacaa tttttcaata aatcagtctt
    22141 ctaaaataga taacctaaaa aaagcgaaca aacaaataaa atgactgtcc ttcattcact
    22201 aaacatattt ttattttttt atattgttaa aaattcgcaa tttatttttt aatagaatta
    22261 tctgttttcc aaattttata acataaaaaa ccttttttaa cggcatttat atgctttttc
    22321 agaaattaac tgatgatttc aaaaagaaaa catgtcataa tatttcccat attgtgcaaa
    22381 aaaatacaag gcggaggctc tactatgatt gaagaatata ttgagaaaaa tattttaaga
    22441 cagctgtttt tatgtgggca attctatgta aataaagaag tcaatctaga aaagctctcc
    22501 aatctcctgc atgtttgcaa aaccacttta ctcaatgata tcaataacat aaaaaaagaa
    22561 tttgaagaac agatcgctta tacacatcgg gaaaaggacc gttacacttt atatttttca
    22621 gaacatatac ctcgatgcaa gatcatgcag caattgtctc aaaattcgtt gtttttaaaa
    22681 acttgtctgc tttatttgga agaagatgaa cctgattatc ttcaattaac tgaatgtgaa
    22741 ttcatctctg tcagcaaagc ttattcatta aaaaaacaag tattagctta ttttaatgac
    22801 tgcgggatcg aaatcgaccg ctactcccct cgattcactg aaatggaaag acgtctgctg
    22861 cttcttaatg tgtcgtatcg tttaggcggt tttaattctt gggagctacc tgaatcgttt
    22921 tttgaacgtg ccgatcgttt cattgaatcc gtaacggaaa atagtggcag attttatgat
    22981 aaagaaaata aagaaatctt atcgattggt tttgctatca gtttcctacg ccagcaagtg
    23041 tgtgctgtga caatagattc aaaatttatc gaagaaatca aaaaacgtcc tatttacaat
    23101 tatgtcgaat cagcatggga aaacactgat ttccaaacct attataaaaa agaagaattc
    23161 gcctttattt tgacactatt caatctttgt aattatggtt tccattctta tcagttgatt
    23221 gcggaagact ttcaacagct acaccaagtg tttattgaca atactcccga aataaaagaa
    23281 ctagttgcta cctttgaatc tcacttcaat caagaattat tcggaaacca accgttcgaa
    23341 cgtgcgctga ttcatctgat gcgttcggct tgggataact atcaattatt catgccagaa
    23401 aaattttatc ttttaaatga ggaacagaca aatttatata aagaagtcca gacaattttt
    23461 tccagctggt ccagccagtt accttatgat ctacggttga atcctaattg catgcgggct
    23521 tttgtgatcg aattgagcgg aattctccgt ctgacaaaag aacatctgac tatctatatc
    23581 gtcacaaatt cggatgttca ttatctgatt tatcgggaag ccttggaagc tgtaactact
    23641 ttcgattttc aagttgcacc aacaatttat tcaagtatat ctgatataaa gaagtatgcg
    23701 cagcagtcct caaaccgggt attatgtgaa cgtacattat atacaccaga tgcggtccaa
    23761 tatgaaaata ttattcctat ttcgatcaat acgatcgatc gagctatcat ttcagctgtg
    23821 caaaacaaat aaggggctgt gacaaaaatc atgtcacagc ctcttatttg ttgaagatgc
    23881 ccatttctgt aacaatctct tgatacacgt caggctcaca acctcactta ttttggacat
    23941 ctacgggtcc gatctcttta tttaaaaaat aagaaatgat ggttcggata actaccaacg
    24001 ccgctagttg gaaaatatcc tgcaaggtag gtttgataat cgattcgatg atcccagctg
    24061 aaacaagaat ttccaaactt agaagtatat agcctcccaa catcttttta atagcattgt
    24121 tctcgctgac tcggtcgctt tgcacttttg tatggacaaa taaatatttc aaaaaatcct
    24181 tgattgatag acaaacaccc caaaccaata aacagatagc aaagatatca agtcccagta
    24241 caagtttttc gaaatatgga agaagaaact gcatcaactc tgtcgtcatc ctacctctcc
    24301 tcttctttgt ttttctttgt cttctatttc ctgattcaag aaataagaaa tgactgttcg
    24361 aatgataata ataagtgcaa gcttcaaaat atctgtccaa gtcggcttga taactgactc
    24421 gatgatatca gcaacgacta gtacttccaa gcttaacaaa atataacttg ctagcagttt
    24481 tcttgtatct gcattacgag tattacgttc tgcatagttt ttcttgacat gagaccaatc
    24541 aaaaagtttg aatagaacaa gaacgatccc gacaattaag ataccgatag aacaaatatt
    24601 taaaatagca atgatccatt ctagaaattc aattaaattt gagcgaaaca tatacgctac
    24661 ctactttctt ttaatttgtt cctattcttt tattgtaaaa gaaagttacc ttgttcgtct
    24721 atttaaaagt tgttctaatg ataacggttc gcttaaattt ttctttttca ctctcccatt
    24781 tttctccctc catccataaa tcgtggaagt atccaaaaca acgtagcaag ttaaaataag
    24841 gcttagtccg tcatcagctt ttcaaagaag cactgtctcg gtgctttttt tgtacccaaa
    24901 tttctaaaaa tagaaccata cacctcctca aatcttttct tcttacctac cctattttta
    24961 tttacaggaa aatcagacac ttcttctttt ttgtcaaaat ttcctttttc ttctcgtcct
    25021 atcatttggc attctaataa aaacgaacta tccttggata tagaaagaga aaacaaggag
    25081 gcgtttttca tgagtaaaaa attaatcaaa gtcggcatcg gtttaggttt gcttgccctt
    25141 ggcgctgcat atctaggaaa aaagacagga ctattcgaag atgacagtca tttatatgat
    25201 gaattcgaat caatctagca tcctatttag ttgaatcact acggacatac ttggaagaca
    25261 ttggaggaat cacaatgaga aaaagtaaag caataatgat tggtgccggt attgccaata
    25321 tggcagcggc tgtttatttg attcaagaag gcaaatggaa aggggatcag atcacctttt
    25381 attcattgga tgatcacggt tcaaatgatg gtgcaccgac cgacactgta gtggatgaat
    25441 attggaataa aaaccatcca ttagaaaacc aaaaaggcta tattgctcga ggcggtcgca
    25501 tgcttaatta ccgtacctat gtagatttga tggatctgtt aagtcgaata ccttctgtta
    25561 ctgagccagg gatgactgct gaagaagata cgagagattt tgatgcaaaa caccgaacct
    25621 ttgacaaagc acgtttgatg gaaggtggca aaggaatcat tgatggcgga aaactgggat
    25681 tcaataataa agaccgtatt cttctgacta aactgattgc tatgcctgat tcagaagaag
    25741 aaaaactaga caatatcact atcgaagaat atttcaaaga tgatccacac ttttttgaaa
    25801 caaacttctg gtttatgtgg gaaacaacat ttgctttcag aacacgtagt tctgctcaag
    25861 aattgcgtcg ctatatgcat caaatgattt atgaattcac tcaaatcgaa catctagtgg
    25921 gcgtcaatcg aacacgttac aatcaatacg aaagtattat gcttcctttg atcgagtact
    25981 tgaaagaaca aggatgcaaa atcattttga accgccgtgt cactgactgg gaattcaaag
    26041 aaacaccgat gcaagatgaa atcactgtga ctggtttgaa aattaccaat acactgactc
    26101 aagaagaaga atacgttgtg gtcgatgaag atacagcagt tattttcact aatgggtcca
    26161 ttacagattc agctacttta ggagattacg aaacaccagc tgtagaaaat atggattatg
    26221 gtgcagcttc tagtctctgg aaaaaagcca gtgaacgttt ctacaacttg ggaaatcctg
    26281 acaaattctt tgctgatcga gatgcaagcg aatgggtcag ctttaccctg acgacgaaaa
    26341 accatttgtt gttgaatgaa atcacccgta tcacgactca agaaccagga aatgccttga
    26401 attcatttat ttcaaccaca ccgatcacgc cgttaggcca aaaagatgtc aatatgtcta
    26461 ttgtcgtgca tcatcaaccg cattttacgt ctcagaaacc aaatgaaaca gttatttggg
    26521 gttatttcct ttatccaaga cgacgtggcg aatttgtgga taaacagtat attaaaatga
    26581 atggaaaaga aatgctagaa gaactgattg gacaactttc aaaagtagat cctggaccag
    26641 tgaatattcg tgaaaaagaa acagaaattt tcgacagcgt aataaataat atccctgtct
    26701 atatgcctta tgcttccgcg ttgttcaata atcgtgccaa aagcgatcga ccaaaagtca
    26761 ttcctaaaca ttcgaccaat ctggccttta caggagaatt tgtcgagcag ccttatcaga
    26821 tgatctttac tgaacaaagt gctgtacgtt ctggagaaat cgctgctttc cattttgcgg
    26881 gtattcctat gtcccgtctt gtcaaaacac cgcgttacga caaagatatt cctactctag
    26941 ctcgtgccgc aaaaaaaatg tttgaataat caagaggttg tgaaaaagct gccctgcatc
    27001 aagtaataag aacaaccagg ctaaaacagc ttcttatgtt tttgatttgg ttggacttat
    27061 taccgcagat gcaagctttt gaacaccgtt taccaagagg ttatgaaaaa gctgccctgc
    27121 atcaagtaat aagagcagcc aagctaaaac agcttcttat gtttttgact tggttagact
    27181 tattaccgca gatgcaagct tttgaacacc gtttaccaag aggttatgaa aaaggcgttt
    27241 agtttcgagt atgaagaaaa attttgtgaa aatggttcct cacgtttttg cataaatttg
    27301 acttaatacc gagaaactga tcccttctgt cataacctct ttttatttat gtctgtttct
    27361 ttttgaaaac aactattttt tcaacgttta ctctcttgcc aatccaacat catctaacgg
    27421 atacaactat ttcaatgatt accattacac taaaaaatcg gaaacacacc tctccgaaca
    27481 caaatacata agactataga atgtttcatt taagaaaaaa agcgtttcat tatcaaaaag
    27541 gtaagatctc ctttaaaatg aaattatctg tagtactaat aatgcagaca attttatgaa
    27601 tctgaaagga gcatctccaa tgaaagcagt cacttggcaa ggaaaacaga aaatggaaat
    27661 cagaaacgta gatgatccaa aaatattaga accaacagat gcaatcatcc gtatcacagc
    27721 aacagccatt tgcggctccg atctgcatct ttaccatcat ggtgaagcag ttttggaaaa
    27781 agggtatgtt gtaggacacg aaccaatggg aatcgttgaa gaagtgggat ctcaagttca
    27841 aacattgaaa aaagggcaac gtgtggttat cccttttaat attagttgtg gtcattgtca
    27901 tttctgcctg aatcacatgg aaagccaatg tgatgaatca aatccagatc agttatatgg
    27961 cgggcttttc ggatttggca agttgaacgg taatcattgg ggtggtcaag cggaatatct
    28021 aagagttcct tatgcagact ctacttcatt tgttgtacca gataatgatc ttcctgatga
    28081 aaaagtttta tttctatcag atattttgcc cacagcttat tggagcgttg aaaacgcagg
    28141 agtaaaaaaa ggcgatacag ttgtgattct aggttctggt ccagtcggtc tattcgctca
    28201 aaaattcgct gttatggctg gagcagagcg cgtaatcgca gtagatccag tacagcaccg
    28261 tctagataaa gcggctaatt acaatggggt tgaaacttat ttcttagaag acacggcaca
    28321 agctggaaca gaattgtatg aactggctaa aggtggcgca gatgtcatta tcgattgtgt
    28381 aggaatggac ggattagagc ctgtcaaaga aaaagcgaaa aatttagtaa gcttacaaag
    28441 cggcacaatc tctccattac agatggcatc gcaagctgtc aaaaaatttg gaacagtcca
    28501 agtaactggt gtttatatga ctccagcttc ttcttacccg ctgcaagaat tttttatgcg
    28561 ggatatcgct gtcaagcatg gacaggcacc aattatccat ctaatgccaa aaatttacgc
    28621 aatgattgca gaaggactat tcgatcctac acaaatcatt actcattcgc tgccactatc
    28681 agaagcagca caagcatatg agatctttga caaaaaagaa gataaaaata taaaagttgt
    28741 tttgaaacct tgaattcagt aaaaaataca ggtgattttc tttatgccca aaatcaaacg
    28801 aaatacccat gagatcgaaa taggaaaaga agaagatatc gaaatacgag gacgtcgctt
    28861 ccgcttctat ttccaaaatc gttacacatt gatctcactg gctgtcgatt tattaaccgg
    28921 gattttctat atttttggaa gccttgcttc cttaactaaa atccccgatc gatatggcac
    28981 ctatttttat ttggctggtg ctattttctt gacgattcgt cctattctca gaatcgtaag
    29041 gaacattttt atttacgacg aaaaaaaagc aatgaagaga acaagcaaaa aaaaagaggc
    29101 atgagaattt ttcaaatctc atgcctcttt tttcacccta tcgtatcact ttgatacaga
    29161 cgagcggtcg tcccactttc ttccttgacc attgtcaaaa atgtccactc gtatcgttca
    29221 taaaacgtgg tatgatctgt aattaagtaa agtttttcgt acccaagttg atgcatttct
    29281 tttctgattt ccgctaatat ccgcttggct atcccctgct tacgcttttc cggttcaaca
    29341 aacagggcac aaagatttgg tgtcagatca gggcggttat ggaagtcgtt ttcaatgacg
    29401 cccgctcctc cgacgatggt ttctttttca tctaagacca cataccattg aggaatactt
    29461 tccttattag cgattccagt acgaatactt tcctcataca caacagcagg aactccccat
    29521 tttgatgaaa accaattcgc gctttgtttt actaattctg ggtgttctct taatttgatc
    29581 cagttatatg taaccaatgt ttaaacctcc gactaaaata aaacgtttac aaaaattata
    29641 caagtcttta tgaaaattag caatgacaac aatagtgatg taaaaaaaaa aacggaaaac
    29701 aatcacttgt tctccgtttt ttgattaatc aagcatctaa agcttctttt cttctttctt
    29761 ggatcgtagc taccttgacg aacggtagat agatcaaaat agaaagaacc aaattgacag
    29821 cggctagtac accacctgca atactttttg ttgccaatac accgccaata attggtggag
    29881 ttacccatgg aggcataacg gtagctgctg gcactaaacc tgtagaagtc gcaaagtaag
    29941 caacactaac taagaccatt ggtgtcaaaa taaatggaat gaacatgatc gggttcaaca
    30001 cgataggtaa cccaaacatc gttggttcat taatattgaa gacacctggc gcaatcgaca
    30061 agtttgttac aaccatatat ggtttgtttt tacgtcctac taaataaata gctaacagta
    30121 aacctaaagt tgcacctgtt cctcctaagt tgacaaagct gtcaaagaaa ggtttgttca
    30181 cgataaacgg tgcgctatgt ccagctgcga ttgcattaac gtttgcttca atggctggcg
    30241 cattgattgt ttgcatcaaa ggatcgacca tattcgctcc gtgtaaacca aagaaccata
    30301 agaatggtgt gataaatgca agcagtaagg cagatggata agagtttgca agtcccataa
    30361 atggttcttg gaccactgta tagaaagaac ctacgatatc atcaacaccg aatgcagcaa
    30421 aaattgcagc aactaaagca aacgcagaga tagtgatcat tgctggtagt aatgaagcaa
    30481 atgcttttgc aactgccggt ggcacaccat caggcatttt gatgatcaat ttttcatttc
    30541 cgcttaaacg tacaaagatt tctgttgaaa taatcccaac aataatagca ataaacaaac
    30601 cgtttgagct catacctaat gctccgccta aagcgaagaa agagcctaaa gaaatcacac
    30661 ctgcggaaac accgtctttt cggtagccgt tagctaaatg ataagcaagc aagaaagcaa
    30721 tcaagacaga aagaatggca aatgtaccgt tccaagcagc agccccgaat cctttccatg
    30781 attcaccacc aaaaattgag ttcatcaatt cttggaaccc gggaatcggt aagttattga
    30841 tcattactgc taatgctcct aagatcatta acggcatact caccataaat gagtcccgaa
    30901 tcgcaactaa atgccgttgt gcaccaattt ttgatgctac aggtataaaa tgtttctcca
    30961 taaatgcaac aaatttatcc ataaatcttc cctcttttct ttactgtaga ttacgcgttc
    31021 aatcgacgat acagatcaat gatctctttt gctaaatctg taaaagctat agatgtcatc
    31081 agatgatctt gactgtggac cgtcaaaagc gtgacttcaa cgtgatttcc ttgtgcttct
    31141 tgtgtcagca tctctgtttg agagtgatgt gcttggacta aagattcctc tgcatctttg
    31201 attttttcat ctgctaaagt gaaatcacct tttttcgcag cagcaatcgc ttccattgca
    31261 tcgctttttg catttccgcc aaacatgatc agacccatga tggcttctag atttttttga
    31321 tcttccattt attgtatcct ccgataattt ttattatttg tttattagtt tttctgcttg
    31381 gtcgagtact ttttcaccat tcatcatgcc atagtcagcc atattgatta catctaaagg
    31441 aatgccttta ggtgctagct tttcagcaaa ttgattttgc ataaagcgta cttgcggtcc
    31501 taaaagtaaa acgtctacat ttttagattc tagttgatta tccgcatctg aagcagatac
    31561 agcaaagatg tctgcttcca ttccttttgc ttctgctgcc ttttgcattt ttgtgactag
    31621 gagacttgta ctcattccag ctgaacatac aagcatgatt gttttctttt ccattttaaa
    31681 cacgttcctt tctatactta cacttgtata taagcaagta gcgtgccaac tttaaaagcg
    31741 ctttaaaaag ttgatatcat cacatttaag gtctatacca agttgcatac acactaaaaa
    31801 agaaagcgca cactaaacac acaaattaat ttttattacc ttttttcttt taacgtgcac
    31861 aaaaaaagtt gtgacacaaa acttgtcaca acttttttca aataaacggt attcaaaagc
    31921 ttgcatctgc ggtaataagt ccaaccaagt taaaaacata agatgttgtt tttactttgc
    31981 tattcttatt acttgatgca ggacagcttt ttcacaacct ctcaataaac ggtgttcaat
    32041 cagctgaccc tgggtattag ctcaaaacgc tggattcaca acctctttta tttcaaataa
    32101 ccagtaaata caatgaacat ctacaaaaaa cttctattta tttatagatt tcgtcaggca
    32161 aatccaattc tctcttatca atcaaagtct gataccacga agcagatttt ttcaatgttc
    32221 tgcttcgttc atcgttcaat tcgattcgaa ctaatccata tcgattctta aatgcattca
    32281 ttggtgacac acagtcagtg aatgcccata acatatagcc ttcgcaattt gcgccttctt
    32341 ctgttgcttt gatcaagtaa tgcaaatgct gtccgataaa ttcgatacgg taatcatctt
    32401 gcacgattcc tttctcatcc atatactgtt cttcatattc tcttcccata ccgttttctg
    32461 ttatcagcca agggatatta tgataatttt cttttagata catggctata tcatacatga
    32521 ttttcggata gatttcccat cccctggaat tattcatttt cttcccaggt aaatcaaaga
    32581 cttcataata tcgttcagga tggaaaggtg tctcttcatt ccattgataa cgaggggcgc
    32641 gaacgcgttt aggataatat tgattgattc caaggaaatc tactgtatga tgctgaatcg
    32701 tttctaaatc ctctgttgca ggatcgaaat aaatcgattg tttttgacac aactccagga
    32761 actcttctgt gtagtatcct tttaccatcg gatcaaaaaa tactcgatta taaaacaaat
    32821 catacatata agcagctttt tggtcttctg gagaattgga tcgagcatag accatttcag
    32881 gatttaaaat acagccaatc cttccaccat aatttccgct gcggtaaatc tctactgctt
    32941 tagccgttgc taaaacttta tgataattcc acatcatcca cttttttgtg ttttgttcat
    33001 gcggccagcg aacagcatcc aaatagcaac gcgtttgggg aacgattggt tcgttgaatg
    33061 taaaccagtt ttttacccta tcaccgtaac gatcaaaggc aatttgagca tacttagcat
    33121 aaaaatcaac tacttttctt gaagaccagc catcatattt ttccaaaaga aaagctggga
    33181 cttcataatg ttccaaacaa atcatcggtt ctacgtctgc ttcgatcaaa gagtcgatca
    33241 tttcacttat atgctgagca tattcttcat ctactataca gttctcataa tcagtaaaaa
    33301 aacgagccca attgatagaa gtccgataat gtgtcagatg gatggatttc atcagatcca
    33361 catcctgctg gtattgttcc ataaaattag ttgctacggc tgggccatac ccattatgcc
    33421 aaacaaaatg ttcattttta taccagctat ctataaacga atcctgtcct tctttttttc
    33481 ctttccaacc ttccgtttgc caagcagaag atgcagcacc aagaataaaa ttttttggaa
    33541 tagtaatttt catgatttcc tcctgttttt tagatcccat cattttccac acgatttgct
    33601 acttttacaa atggcagata gatcaaaata gaaacaataa tacaaacaag ttgcgtaata
    33661 actgcaccga tatttcctgc tgttgccaga taagcattga cgatcggcgg cattggccaa
    33721 gggaccatta caactgcttt cgccgcaaat cctaaagcgg ttgcaaaata accaatcgtt
    33781 ccagtgataa gaggcgttaa gataaacgga atagctaaaa ttggattcag catgatcggc
    33841 ataccaaaaa taactggttc attgatgttg aagatcccag gagcaaggga taacttggtg
    33901 atttgtttca tatcttcccg ttttccaact aacaatactg caatcagtaa accgatcgtg
    33961 actccagacc cgcccatact catatacata tcccaaaatg gcatagtaat aatgttcggt
    34021 acttcttttc cagcttcaaa agcttccgta tttacagcaa ttgccgctaa aagcaacggt
    34081 tcccgtatcg gcttcaccat ttgatttcca tggataccaa tcacccaaaa gacttgcgca
    34141 ataaacatca atagcaaaat acccggtaac ccttgtacga caccttctaa tgggcgttgt
    34201 acgacattgt aaatgatatc ataaaggtac attcctgtaa gttctttgat gataaatccc
    34261 gcagccgcga tacccgatac agtcagaatc gtcgggaata aagcagaaaa actagcagaa
    34321 acattcgttg gcacggtatc aggcattctc agctgtagtt tcttctgttt cctcaaccag
    34381 caataaagtt caatagaaag gatggagacc aacattccca aaaataaccc tttcgtatct
    34441 gtatattgtt tagccaatac gttttctact ataacagtct gattttcatt cactaattca
    34501 taaacagttg gattaacaga taaataagac atcactgcga tgataccagg gaatacacca
    34561 tccactttat tcagcttggc taattcgatc cctatcagaa aaacagcata gatggtcaag
    34621 aaacttagtg tgacatagct gatggcagat gcgataggct ttaattcttc taaaaaacgc
    34681 aagaaactta tctgtgctaa gccattttcc gagtcaaaga ccattgctga aaacaatgtg
    34741 ccaaaagcac ccgtaataat taccggaatc aatgcagcaa atgcgttttt tatcaccatg
    34801 atatacctta aattattgat tctcgttgcc acgttcccta aaacattggc taatttatcc
    34861 ataaaactca ttccagatcc cctcattcct gcttcttctc cttgacgtca tctctttttg
    34921 tctattagtc agcgcttaca tttcgatgaa cagaaactat ttactcctct tttttaccaa
    34981 atataaaaca aaaattcatc tgatgtattt atcataaaat acatcagatg aactgtcaat
    35041 tagtttcttt ttctcctatt attttctgta attctctccg atttattgcc atatggacag
    35101 tcattgcatc aaacgcagca agtgcattcc gcctttcgat ggcctgaacg atctctgtat
    35161 gaatatcgat cgtctcgatt ttcagatgct ggatatcata atttttatta aacaaagcaa
    35221 ttgattcatt aatgattggg ataatatgca gcaaggctac gtttccgcta gcttctgcaa
    35281 tcatcgtatg aaaatcgatg tctaattgaa catgttcttg tgtgccttct cgaaaagaag
    35341 tttcaatctt ttgcgttaat tttttcattt ggacgatttg attcttcgtt gcatattccg
    35401 ctgccaaacc tgccatctta ggctccaata aatatctcag ttcaaataag tctcgtatca
    35461 tccgatcctg atcttcaatc aaagaaaaac cgagtgggtc attggcaatc cctcgcttat
    35521 cactgacaaa tgtccccgct ccttgccgaa cttcaaggat attcctggaa gctagagccc
    35581 gcacagcttc tcgcaccgtg cttcgcccca cctctaaata atcggacaat tcatattcat
    35641 tcggcagttt atctcctact tgcaactgca tttcctttaa atatctaagg atcttgtcag
    35701 tagttacttc tactagggtt ttattttctt ccaaaccaca tacctccttt tcatctgatg
    35761 tattttttcg taattattat aacacgtttg aatcatctga tgattttttg tatacaaaat
    35821 tgattaatcc gttcatagac atacaaacga agaagatatt taccataaaa aagactagga
    35881 taaaattcac tcctagcctt cgatcatttt tattttgaac gacaaaaaat atgatgttca
    35941 ataacagacg atcttcattc gattcttgat gtcatctttt gtttttttta atatatggat
    36001 aaaaagtttg attacatcgt ttctattcta gaatttggtc gattctcaat tcttcttctg
    36061 gtgagaaatc taaattatcc atcattcgaa cactttcttg taactgactt aaccgacttg
    36121 ctccgaccag tacacttgta acagattttt gtcgcaaatt ccatgcaagg gccatttgcg
    36181 ctaatgattg tcctcgtgat acggcgattg tttgcagtgc tttgattttt tccagagttg
    36241 atccaacttg ttcttctgaa aggaatggta tttccttacg atgtgctcta gaatcttcag
    36301 gaataccatg tagataacga tttgtcagca acccttgagc aagcggactg aacgtgattg
    36361 cccctagccc ttcttcttct aatactggag atagatcgtc ttctagtagt gcacgagaaa
    36421 acatattgta gcgcatctga tgaataatga acggtgcttc ctttcttttt aaaatttcag
    36481 tcattttttt tgtatcttct ccattatagt tggatatacc aatatataat gcttttcctt
    36541 gtcttacaag ttgcatcaaa gcttctgctg tttcttccaa aggtgtatca gggtctgggc
    36601 gatgatgata gaagatgtca acataatcta gccccattct ttggagactt tggtcacaac
    36661 ttgaaatgat ggatttacga gagccccatt ccccatatgg cccttcccac atatgataac
    36721 ctgctttgct agaaataatc agttcatcac ggtaggcttg aaaatcttct ctaaaaatac
    36781 gcccaaagtt tttctctgca gctccagcag ggcctccata attattcgca aggtcgaaat
    36841 gggtaattcc catgtcgaat gcgcctctta aaatctctct ttgattatgg ataggatcat
    36901 aatcaccaaa attttgccat aatccgagag ataaaatcgg taatttcaaa cctgaatgac
    36961 cggatttacg atattccatt ttttcataac gtgcactatc tgcaatatac aatttttctc
    37021 ctcctcatca aatcttttta aaacgctttc ttttttctat ttttagttta ctacatttta
    37081 aagaaaagga gttaatcaaa atgatttttt cgtatatttt tttgccattt gttttttact
    37141 cgttgataga tcagaaattg attacgtgct tgctggattt ttttataacg tttcggttgt
    37201 tttttgtaaa attgctgatg atagttttct gctggccaaa acgtaccggc tggttcgatt
    37261 tttgtgacga ttggttggtg gaaagttcct gaactgtcta gtttctgttt tgattgttcc
    37321 gctaattctt tttgtcgttc gacttgataa aaaatcactg gacgatattg cttccctcta
    37381 tcttgaaatt gtccaaatgt atctgtggga tcagtaattt gccaatagat tgtcagcaac
    37441 tcgctataac ttatttctct tgtgtcataa atgatctcca cagcttccac atgacctgtg
    37501 taaccaccac ttacttgatc ataatttggt ttttcaacat gtccgcccgt gtatcctgac
    37561 aaaacagata ggatcccttt tttcgattca aacggctcga ccatacacca gaaacatccc
    37621 cctgcaaata ctgcacgttc ttgatagtca gcatcttgca tggcatgctt ggaaaagtca
    37681 tatttttgct ccttatcaaa tccttccgta atcaataaat aaaagtccat tacatcaggc
    37741 gtcagattca ttcggatagc taatggacgt agtgttgctt ctagttttga taactgttct
    37801 ttaacggata tattttctct tatgtcattc tttgtctgaa tcaatacttt tcgttcccaa
    37861 tctcgtgtat tcggattcaa aatcagatta taaagtgttt gaatgaatat ttgttcctca
    37921 tccatagatt ctcctccttt ccgaagaaga caagctagtg actttagctg taatttatca
    37981 taaagtgagg aaataagcga ttacttcatc cccctacaga tttttcgtat aaaaaagaga
    38041 gaatccttat cgacagattc tcctttttaa tcaatttatt ttataaatga aaagttaatt
    38101 taccttttat ggaaaactat tttaaaaaat aaacataaat atgcagttaa tgtaacaaga
    38161 taagaaataa tagtcgttac tgtataactt gtgcttactt taatatcagc aactcctttg
    38221 actccgctta tttgtaccaa tccattagca ttcacctgct cctttacagg ttgatgattt
    38281 atttctacat tcgttcctaa ataagcatat acaggaagtg tgattacttg gctcttctca
    38341 ttagttactc tatatatgat agaactacca gttgttttat aaggaaggtt tacccattga
    38401 ctgccaatct ttgcttcgtg ttttattata tgctccttat tctccaatga agcgatagga
    38461 gaataatcat ataaaaaata atccattcct ttagtggtat acgcctctac tgtttctttg
    38521 tttacaacaa tatgtcccgg ctgagaaatt attttttgat tgaaattttt tttactagaa
    38581 acagttaaag tgattaataa caaaacagtc ataaataaat aaaatagttc tcttgtctta
    38641 ttgtatcttc tatttttgaa aaatatcatc gttaatatca gagaagagaa tattatttgc
    38701 aagcttaaga tccgccaagg aaattgtaac aatttggctg gcgtattttg cagaagatac
    38761 catggcacca aactagttgt agctagccaa gtcaaacacg taccataata aatctttttt
    38821 tctatgtttg ttaatttttt aaataaaatc aggggaatac ataaagataa cagaccaact
    38881 agtcccattg agtaagtagt taagtcgttg ttcatagctt cagtcagact atcgaacaca
    38941 ttagatgcat gagcatataa atttgtcacg ctaggtttgt tgattttttg gtagagcatt
    39001 tgttcaaaca tcggatacca aaaagcactc gtcagaacca atgtcattcc tgccgcacta
    39061 aataattttt taaatatagc aataaaatct gcattcttga aacctttaga aaccaaacga
    39121 ataaaaataa aaatgataat taatgctgta ctcattaatg ttgatagtac atggctgtac
    39181 actagcaaac tcatactcaa tgctagcttt acagacggat acttttcttc ttttccagag
    39241 atgatttgat aagcataaaa taatacaggg ataacaagtg ttattgcgat agcttcggca
    39301 attgcggaac gatagtagat gtctactgtc cgataagcag agaaaatata gagacaacta
    39361 aataaaaatg ccgctttttt ttgttttaaa aaccgctcgc cataatgata agctacgagt
    39421 gttgtacaca agttcaataa ccaaacgtaa ataatatagc ttacaatcaa attttttgtc
    39481 atccaatata acattacagc tggaaaaaaa gtcagaaagg gataaaaata atttacacca
    39541 tatccagtat aattgaatgt ctcataatta atcggactgg taaaaatagt cgataacccc
    39601 ttgattcgag ataagtgaaa agaaagatct ccagtggtat aaatactctg tgtatttttg
    39661 aaaaagatga aagaatatat actactaact ataattaatc cactcaatat tactactttt
    39721 ttatttattt tcattcttct tgtttatctc ctttttagtc acatatcgag aatctttcaa
    39781 cttattaggt gcaaatcgtt taaaacttga atacaccact aaacaataag tcagaatact
    39841 gatccataaa gccatgagag cagttggagt atattttgtt gtaatttcta tcttattttc
    39901 tccagcattt acatccacat tcactaagcc atgtttttta taagagtcat ttacgacttt
    39961 accgtttact tttacctgtg tacctaaata agcatatact ggtactgtca ctttttgctt
    40021 tttgttgctt gccactgtgt aagtaatgtt attatctgca gctttatact tccctttttc
    40081 ccacgattct cctactttta cttcatgttt ttctaagtga ggcctttctt ttatcgcttc
    40141 tgttggggcg taatcgtata atcctcccat atctgatgtt gtataacgtg ggagtgtttc
    40201 ttcattgata acaatatgac cgtgttttga ttggataact tttgcgtaat tttcttttgc
    40261 tgctatagac gtgacgagta gaaacaccac agtagcgcca atgattaacc atgaatattt
    40321 tttattcata gtctttttca taaaaacaag cgttatgatc attgaagaaa aaaagatttg
    40381 gatacctaag atacgccaag gaaactggag taagcttatc ggtgtttttt gaaacaaaaa
    40441 ccatggaaat aaattagtta cgcataccca tgtagaaact acgccaacat agatgatttt
    40501 ttcttttttc tccatttctt tcagtatgaa taaaggaaaa atcaacgcaa ccaatcctaa
    40561 taaccccata gtgtatgttg taatatcgtt atttaacgct tgaatgatac tatctgaaat
    40621 agaaagtgct tctagctgca aatctgtttt gaagggactg tgtatttctt gataattcat
    40681 ctgctgcaac ataggatacc aaaaatagct agttaatgca caagtcaaaa aaacagcctt
    40741 tactaaattc acgaccacaa attttatatc gttttttatt tgcttgctta aaaacaaacg
    40801 aactataatc atacaagcaa tcaatgcact acacaatagt gtagttaaga catgagtata
    40861 cacaagtaga cttatactga cagataaagc gatgactttt ttttctctat tgaatatcaa
    40921 tccataagca taatataaaa cagctgggat aatcgtaaga gcgattgctt ctgcaattgc
    40981 ggatcgataa tagatatcaa ctgttcgata agttgcaaaa gtatataaac aactaaataa
    41041 aaaagcagca tctatctttt taaaaaactt ttctccataa taaaaactaa tcagaatcgt
    41101 acaaatattt aataaccaaa tatatagaac ataacttaat attaagttat ttgaaattcc
    41161 ataaaaaacg actgcaggaa ttattgtaag aaaaggataa aaatagttca gtccatctcc
    41221 ataattgtta aatgttgtat agttgattgg cccttcaaaa atagaagata accctttgat
    41281 tcgtgaaaga tgaaaagata aatcacctgt tgtataaatt tcttgagcat ttctcataaa
    41341 atttactgaa tataaagtac taagtaagat aagaactact aaaagaaatg cttttttact
    41401 tattttcata gatttgttgt tctccttttt taattctatt ttcagtatac tagaattgtc
    41461 tttttttaat aagttttgcg ttaaattttt catagcacta gtatgatata ctagaaaaga
    41521 atcaattttt attactttta aataggagaa aaaaatgaaa aaaaacaaaa accaaataat
    41581 agatatcatt tttatgttat ttctaagttt tgcttacgtc atccctctat tcatgtctaa
    41641 gggaatctat catagtgtca atcaggatac ttactttcat ttatctcgaa tcataggact
    41701 agataatgta tggagttctc cagtaaactt caataacttc gatcatcatg gaacaatgat
    41761 gaatattttt tatccatggc ttactcttta tccagctttt ttattttata aaatgatggg
    41821 aaatcttgtt ttaagttata atatctacta tttttttatc acttttttaa caatggtcgt
    41881 ttcttatttt tctatgaaac aaataaaaaa caatcgttat atttcgctgt tattttcgat
    41941 tatttataca ttttccgcct atcgtgccat tgacatattc catcgtgctt cattgggaga
    42001 agctgtcgct ttaacatttt tgcctttgat actaatgggg tgttacgaaa tttatattag
    42061 agattaccaa aaatggtact ggttgtctat tggcatgacg ctagtagtgt atactcattt
    42121 actttctgtc gctatggttt ctgtatttat tggaggaacg ttgtttcttt ctttttattt
    42181 ttgggaccaa aaaatcgcta gactcttaag tcttttaaaa gctaccgtcc tcaccttttt
    42241 tttaagtgcg ggattcttaa ttccttttat tcaacaatct agagcacaag aattgaaagt
    42301 cccactggga aaagaattaa gtggtatggc tcctagtgat atgctgacac atattttaaa
    42361 taataactat aacaactata ctattggatt attcttattt ctcggattga ttggtgcttt
    42421 tatttttata aaaaaattaa ctgctgatga tttatttatt ttctttcttg gtgtatttgt
    42481 tcttttttgt tcaaccaatt tatttccttg gcaacttttt aaccatacac cagttaagag
    42541 tctacaattt gtctggcggt taaatggttt ttcttcttta tttatagcct atacgatgag
    42601 tatagtgatc tattatattt tttctactaa aaataattca tggaaaataa tggtctttac
    42661 gtttcttgca ctaatattgc atctctcagg agtaagcaat tctatccatg ctaacaaaga
    42721 ttcattaaca cttatagcac ctgaagacgc tgttgctata gctgaaaatt acaatcatac
    42781 tgattatgca aacaaagagt caatctatca tcctgatatg attaataatg atcaatattt
    42841 actaggtaac caggaaataa atccaacaac tcattttatg agtaacaaac ttacaattga
    42901 attagataat tcgaataata aaaatactgt cttgacgaca cctatttatc gttataaagg
    42961 gcaagtggct tctattaatg gcaaactagt acaaacaaaa ttatctaagt ttggcacaac
    43021 tgaattaact attcctccag gtataaataa agtcgttatt acttatcagt acacaaaact
    43081 agcaattgct tcaagatatt tatctatcgt tactttgatt ttatttttac tttatcgatt
    43141 tactttttct aaacaaaaac aaccgagaag agaagtacaa cattctcact agatttttat
    43201 ttaagaaaga ctttttagct gtacacataa acaggctaaa aagtcttttt ttatatttct
    43261 ttaatttgct tcatacatta tttaacatcg atatttatac tgtgaaacat gcgtttcatc
    43321 cattatcaaa gtatttttat cgataataaa cttcatccaa aaacagacct tgtgcaggga
    43381 cggtttctcc tgcatgttgc cgcactttgc tttcaaatat ttcatcgatt gtttctatcg
    43441 gcatggcacc tgtgccgatt tctagtaatg tccccatgat aatccgcacc attttatata
    43501 agaatccgtc tccgacaaaa gtaaaatgaa gcatttctcc ctttcgttcg atagataatt
    43561 catcaatcgt acgcactgtg gatttttttg attttttcaa tgcagaaaaa ccaatgaaat
    43621 catgtgtacc cactaatttt tcgcaagctg cattcagctt gtccatatcc aactcttgag
    43681 ggaaataaaa gctgtggttt cgctcaaatg ctgaaggaat cacgttgttc caaacataat
    43741 agctgtattt tttgcccacc gcattatatc ttgaatggaa gcgctcaggc atttcttcga
    43801 ttcttttgat gacaatatcc cgcggaaggt aacgattcat aaagtcgatc atttctgcca
    43861 gtccaatttc tgtgtttgtt ttaaaatttg ctacttgtcc tcgcgcatgg gtgccagcat
    43921 ctgttcttcc tgatccaata atttctatct cttcatttgt catctgatgc aatacttttt
    43981 cgatttttcc ttgaatggtt ttatcgtcat ctccaagtct ttgccatcct gaatatcttt
    44041 ttccgtcata ttcgattgtc aacttgatgt ttctcatatt ttagtggctc ctctgtcttc
    44101 catttggtct tctctctacc tttttaagat tgtagcacaa aatatagctc cttgcttctc
    44161 taagacagaa gctatacaag aaaactgtgg aaatatatat ttcagaaaaa caaaaaacag
    44221 ccaccggatg aagtatccgc tgactgttca atttgacggc tcaagtttta ctgtttgaga
    44281 tgcaagatac tcaaccaggc aatgggcaca taattaaaga aaaaactgat tctttggcaa
    44341 aaacctattt tattcagtaa tggccaagaa tttatagaag gaattcttgc cagtccataa
    44401 atcgccgcaa aaagcaaact gatcacagac agtccaaggt ataagtggct tacgtccatt
    44461 tgcccatttt ttcgatagat caagaaaaga agaactggaa acaataaaaa accactgtaa
    44521 cctaaacctg atccgatatt atggacccat gtcgagacat tccacgaaga ttcatgggta
    44581 ttgatactga acaaacctgt aaagatacaa tcacctatac catagaacgc gatggctgct
    44641 gtaactaggg tagctaacac acgagatgta ctaacaaatg cagcatacaa tgcaggcaat
    44701 gacaggatga aaaagatccc tgaaaccaca gaccaaataa gaaacgcttt tcttacagga
    44761 ctggaaacct ctccaaatac actgatcacg ctcttcattt gatctaattc aggataatac
    44821 aatcctaata cgtacggagt caaaaaatca ctcagcacgc ctaataataa aaagaaaaaa
    44881 ccaaatttac gtaaaaaatc catgatacgc ctccaataac aattacctat gcttttaatt
    44941 gttattataa acgactttat cttgatttaa cagaaacctc tatttacacg aacatctata
    45001 taactcatta aaaactcgaa tcattttaaa aatactaaat atctaacgtt caacgttcac
    45061 ttaatccatc taaacaatct ttcaatttga ttttttcccc acttctttta cgcgcgccta
    45121 gctctcctat tgcagtaaac aacagatcac ttgacgaatt taaggcagtt tccattgaat
    45181 cctggataac accgataata aatccaatac cgacgatttg catcgcgaca tcattagaga
    45241 taccaaacaa actacatgct aatggaatca ataacagtga accgcccgca acacctgaag
    45301 ctccacaagc agctaaagca gacaaaatac ataaaaggac tttcaaaaca aaaggtgctt
    45361 caatccctaa agaatgtaca gcagtcaacg tcatcaagga aatggtaatc gcggcaccgc
    45421 ccatattgat cgtagcacct aacgggatcg atatggaata agactctttt gtcaatttca
    45481 atctttcagc caacatcatg tttatcggga tatttgcggc agaacttcgg gtaaagaaag
    45541 cgggaagtgc gctttctttc aaacaaaaga aaatcaatgg atagggattt tctttaataa
    45601 acaaaaacgt gaggaatggg tacacaacta atgcgacaaa cagcatcgta ccgatcaaaa
    45661 caagtaaaag ctgcagatac tctgccaatc cagcgattcc agtcgtagca attgattgat
    45721 aaaccaatcc taaaatccct atcggagcaa atgcaataat cacttgtacg acttgtgaca
    45781 acgctataga tatctgatcc accaactctt ttgtcgattc tgaacgtgct cgaaaagcta
    45841 gtcccaacaa tacagcccag aataagacgc caaggtaatt cgcatcaata agagattgaa
    45901 caggattttg tgtgacattc gtcaacatag tagataaaac actttccaaa ctttgcggtg
    45961 ctttttcaga tactgtttct tgtaaagtaa taggaacagt aaaaattgaa cttacaataa
    46021 ctgctacaag tgcagaaagc aatgttccca ctaaatataa gatcaaaata ggcttcacga
    46081 atgtcttatt cccaatttta tgcttggcaa ttgacgccat cgtcaagaaa aaaaccagaa
    46141 taggtgcgat tgccttcaag caactgacaa acaacgttcc caatattgaa ataaatgtcc
    46201 atgtggggaa aaagatacca aacaatattc cgactaaaat accaacaaca atacgttgaa
    46261 ctaacgacat atccaaaaac ttctctaaca aatgaccacc ctttcacaat tttaacaatc
    46321 attgtatcat tttatgcaaa gaaactaaag gtataatttt ctaaaaattc taacaataca
    46381 aacaaccatt tcttgctaat tttgtacttt ttctgtctac acgttgtttt ttgagatatt
    46441 ctaagttagg atgttattaa tgggcaactt atcaggaaac gttttcttat gtttttgtcc
    46501 aatttttttg tgaggtgttt attcttgaaa aaaataaaga aggagagtta tggcttcctg
    46561 acaatctttg tcgcttgtat aatgatggtt ttacagcgta tattgatttc agcagtcact
    46621 attcctacat atgcaacaaa ccctggtcga ttctacatct atacattttt acaaacttcc
    46681 gttgttattg gtgcaaattt gatcccactt tacatgggtt accaatatca aaaaatcgcc
    46741 cgtttaaaag ttttacatta tttaagtcgt tttgccttta tattcctaat agccacacta
    46801 gtttgcaata tcttttttta cgtacaagct ggcagcttga atattcgtga ttattggctt
    46861 atcctaacac ctatcagtca gaattacttt acttatgctg tttcttgtac tttgcttttt
    46921 tgtagtattc cttatacagt tggattttta aataaattat cgaaaacaac aattaaatat
    46981 ctactattat ttttaacaat tggattagtt ggctgctcta ctctatttaa taaagacccg
    47041 tttgcattac agaatggaca gagtatttta tggatttttt atttattttt aatgggttat
    47101 ggtttgaaag aatggaactg gaaagaaaag gtccgctata agcttcctca agtatttatc
    47161 agcttgattg ttttattcgg tttgattatt ttgatgacac aaatttcact catcatcaga
    47221 ggaaatacag atacagcgct gaggttttct aaaccatatt ctctcttcgc aatgtattat
    47281 actttctctt cgtttttatt tttagaaatg ctatctgata aattaggtat aaaaggaaga
    47341 ggaaattttc ttgctgtatt tttgattgtc actcaagtta tatgtaattt ccctttagtt
    47401 tcttatcgcg tatctacatt tatgaaacgt gaatttccaa actcagggaa ggcatggctg
    47461 ataaatatcg ggcagttttt tatttgatat ttattagcag tgtccctcct agttatcttt
    47521 ttattttata tacaaaaaat ccgtttcatt catcgtttca tcgaatactt cgcttttgat
    47581 tcgattgaac aattaactca gcgttggaaa aaaagaattc attggctttt tgttcataaa
    47641 agttattttt tagttgcagc atttttttac tgctttacct tcgtgcagat tttcgtttta
    47701 gaaccaaaag aaggttggaa agaaactatc caggttgcct taaaaatatt tactcagcga
    47761 caagcaccca tgatcctgac aatcatcatt attatgggat ttttcttctt actattgttg
    47821 atttccaatc gtttttggta cgccttgact gctaccttga tcattaactt actgctcact
    47881 atttcgacag taatcaaaat ggaaatgcgg gaagagcctg tctttccttc agatttaaaa
    47941 atgctgaccg gattgtcaga actattatcg atggttagcc cagtcttatt aatcgtgggc
    48001 ggattgatcc ttctcctatt attgattact agtattattg tacaacgtag actacaaaaa
    48061 cagtattcct tgaagattca ttggaaacgt cgatttatca gtatcgctgt attattagga
    48121 tgtttttcgg gtgtcttttt cattaatcac aaaaattcgc cttctttctt gctgtttaat
    48181 ttatttaaag taaacaagac tttctttaac cagcaaggcg ccgtaaaaga taacggacca
    48241 gtcattcaat tcctaaacaa tatcgacatt aaaatcatgg aagaacctgc tggctattcg
    48301 aaagaaaaaa ttaatggaat aatgaaaaag tacaacacaa aggcagatga aatcaaccaa
    48361 acaagaagtg actggttaaa caatcagacg atcgttctca atttaagtga aagcttcagt
    48421 gatcctgcac gtgtccctaa tctgacagta cctacagacc ctattcctta catcaaaagc
    48481 attataacag aaggaacagg aggattgatg ttatccgtcg gttatggtgg cggaacagct
    48541 aacatggaat gggaaggact gacaggcttg agtatcagta acctgtctgc ttcgttagtt
    48601 acaccttata cccagctagt ggagcgtcag aaaataagtc caaatattac cgatctattc
    48661 gatgaaaaaa tagccatcca tccttttaca gctgctcttt atcgcagaaa acaagtgttt
    48721 gataaatttg gttttgacag gttctattat ttagacagtc cggataaatt aacttatacg
    48781 gataaaatag aacaaagccc acgcatatcg gatgattcag catacaaaga aaccttgaaa
    48841 gctttacaaa gcaatacgga aacgtcacaa ttcatccaat tatccactat gcaaaaccat
    48901 atgccttatg atgattacta tagtgaattg aactacactg ctgaaggaac tgctgtcatt
    48961 cctaatagaa gaaaagaatt acaaacttat atgcaaggcc ttcactatac cgatacagca
    49021 gtaaaaaaat tcatccaaga aatcgacaaa atcgataaac cgattacctt tgttttttat
    49081 ggtgaccatt tacccgcaat ctatagtggg aatgattcga aaaaatatgg attagaacag
    49141 caccagacag attatttcat ttataacaac aagtatagtc gtgaacaagc agctacgtta
    49201 aataaagaag ttgttgctcc taataacttt ggtgctatgg ctcttgagca tgcgaatatc
    49261 aaagtaactc cttactatgc gttgttgaca gaagtatcta atcatctacc tgcattaaca
    49321 attgatccta cagaaagctt gtctaatcgt tttaatggaa aacaggtctt tgttacagag
    49381 gatagtcaaa ttatccaaga aaaaaattta actgagaaac aaaaagaaat tctagaagat
    49441 tatcgtctga tacaatatga tcttgttgca ggtaaccagt acagtgcaac atgggcgaca
    49501 caaaaaataa aagactaaca aataaactga gcaaggggtt gtgataaaag acatgtcaca
    49561 accccttgtt tatctcatta atttgcttgt ccataaacga tttgattaaa gccatttttc
    49621 aattcattat tcgctgtctc gttgaagtaa agataattat cgggattccc ctgattttgt
    49681 tgtgtcacca atacttttgg ctgattttgc tgaaacccga atagatagac gtgctttttc
    49741 agatatggtt ctgtctctgc atcggaatag acggctgtga tttgatagtc tgcttgacct
    49801 gtcccacttt ctgaccattc tgcagaaaca ggcactccac caatagccat cttccactcc
    49861 ccgttcaaaa tagcttgagg gactttaaga ccatataagt ccacactcat ttgattcgta
    49921 taacttttgt attgttgtcc cattgtttgg ccccatttgg tcataaatgc ctctaattgt
    49981 gcggatttgt ctgcattcca cagtgtttgt tcaacttgtt cgctgctttc tgaagaggaa
    50041 gatgaagcct ctacagaaga acttgaagta gatgtttgag ttgtttcagt cgttttggaa
    50101 gactctgacg aagtagaggt atctgctgtt tctgtacttg ctgcagttga cttgctctct
    50161 gtgctagttg ttgtagtagt tgcaactgtt gctttcgctg tttcttttgt tgattctttt
    50221 ttcgattcat tcccgttggt acaaccagct aacaaaaaag ctagaccaat tgttactaaa
    50281 atcctttttt tcaattaaaa aactcctttc gattactccc acttctttat tctatcaaat
    50341 aagcaatgtg attttattga tttttcgtat tttctcatca atctttcaaa tcttctaaaa
    50401 actgagaagc acccgctgat gttgtctgta atacatcagc gggtgcttct tttattttaa
    50461 tcttcgtgat tttccaattt acctcacgct ttatatttgt atttgaagaa acatagactt
    50521 ttagtcatca tcgtcttcct catccaaatc ttgtcggaca gtttttcctt ggagtctttg
    50581 tacttggtag atgatttctt tattgaaact taaaagttca acaagcaatt gttgcaagcc
    50641 atatttttct tctttttcag ctaatttgat tgcccgtgtg ataaagacat tttggaaatc
    50701 aaaatctttt gcaaagtttt ccaacattgt tgaggctggt aaatatttgt tttgaccatg
    50761 ttcgtaaatt tttccataac gcatgacttc ttctaaagta gacggaacga tttcattttc
    50821 aatcactaac tcatgagaga ttttattgaa ccatctcgct tcttgatcag catattctga
    50881 aaaaagggta cttaattctt gcgaagatgt acccaaaaca tacaattgtg cttggatcaa
    50941 tttcatttct tctaatttaa aatttgctaa tacatgcccc accatggcgc cagcagttgg
    51001 tttatgatgg tcgatatctg cttgttttgt ttcttgaaca aatttttctt ccactatatt
    51061 cattgattta cgcctctttt acttttgctg attggacttc ataacctaat ttttccacaa
    51121 ctgcagctaa ttgttcaggg tggacttcat ctggatcaaa gtttgctttg attttgctcg
    51181 cattaaacaa aactttcgta ttgcttaccc caggctgttg agaaaccgca tgttcgattt
    51241 tttgcataca gcttggacaa gctagtgtat ctaattgcat aataattttt ttcatcgtag
    51301 ttcttccttc ctttttcttg atagtcttat tctagattac agcttccata aaaaaattga
    51361 ttcttatcaa gttttacgat ttttcttctt tgctttcgtg tccaaaatac aataaacgca
    51421 tcgcgttaaa gataacgatc aagatactag cttcgtgaac gaacatccca ctagccatgt
    51481 aaataaaccc ggcaaataag ccgttgagta aaaataagac gacaccaatg gcaatcacta
    51541 cattttcacg ggtatttaaa acagttttct tagccaagcg gtaggcatga accaacgatt
    51601 caaaattaga ttgcatcaag acaacgtcac tcgtttcgat agcaacatcc gttcctgatc
    51661 ccatagcaat cccgatatca gccgcagcca aagagggaga atcattgatt ccatctccaa
    51721 taaaagcaac gcgcaatcct tgttcttggt attttttcac aaattgaacc ttttcgtctg
    51781 gtaataattc agcatggact tcatcaatgc ctaacatatc agctacataa tcagcagtca
    51841 tctgattatc acctgtcagc atcactaact gttttgctcc tgcttgtttc aacttagcta
    51901 attgttcagc gacttctggt cgaatcacat ctgacacacc tatgatttga gtgatttttt
    51961 tgtcgattgc tacaataatg accgagctgc ctgtttgttg taattgatgt aaatcttgta
    52021 cttgctttgg tgtgagagaa agtttgtgag cggcaatcaa tttggtgttg cccgcacaaa
    52081 ctgtatgacc atcaatctca gctgtgattc cttgtccctt gattgtctga ttatctttga
    52141 ctgctaattg ttgaaaatca atgtctttct cctgagcata atggatcacg gcgcgcccca
    52201 gaggatgatc ggataacgtt tctaatcgag ccactaaagc taagctgtcc ccttcatcct
    52261 ctgtatagtt cttgatagtg gatacagcag tagttccttt ggtcaatgta ccagttttat
    52321 caaagacaaa agtatcgatt ttggaaaaag tatccattgc ttcaccgcct ttgactaaga
    52381 tgccccgttt cgctccatta ccgattcctg ctacattcga aacaggcgca ccaatgacta
    52441 aagcgccagg acaaccaaga accaaaacag tgattgctaa acgaaaatca cgactaatca
    52501 gaccaacaac caacgcaata agtaaaacgg ttggagtata atactgagaa aatcgatcaa
    52561 tgaatttttc cgcatgggat ttggtatctt gtgcttcttc tactaattcg ataattttgg
    52621 caaaggtcgt atcatctccg accttagttg cttcaatcgt cacgtagcca tctgctaaaa
    52681 tcgttccaga gaagacttca tctccactga ttttgacgac ttgtcgtgat tcaccagtca
    52741 ctgcggcttc atccgcatac cctttcccgt caatgactcg tccgtccaca ggaatagctc
    52801 caccagtttt tactaagacg atatcgcctt cttccacgtc atcgatttcc acttcttcag
    52861 tcgttccatc ttcttggaca acactagcag tagatggggc catctcggtc aaagccttga
    52921 ttgactcccg cgttttggtc aatgtttttt gttccagata gctaccaaac aaaaacaaga
    52981 atgtaacgat agctgactcc ttgtattctc cgatcataaa ggcaccaagc acagcaatag
    53041 taacgagtaa atcaattgag ataactttga ctttcactgc ctgatacgca tggatcataa
    53101 taggtatgac cgcaataata gaagctatgg ctagagcaat gttatagaac aagacaaaac
    53161 cagtaaattt tccgataaaa ccaaaaataa tcaacacagc tgataaggcg gtgatatgat
    53221 ttcgatgctc ttggatccac ttttgtaatt tcatctttct ccctcttttc ctttcattct
    53281 tacgagacta agtatagata cttatccatc ataaaaaatt gaccactatc aagtttagtc
    53341 aaaaaggcgg ttttcttttg gtagaataca ctacaaaaaa tagttagcaa gaagactcac
    53401 taaaagtgat cttgccaact attgtcgttt ctatcgaaat tttcattgaa tgattttcct
    53461 gtacagcata catcggagat ctatttcttt atctaagatt tttatcttgc taattttttc
    53521 ctttagtctt tcaaatccac gtcgttcata gaattgatac gtacagccac tatctgtaaa
    53581 aaggaatatt tcttttcctt tctctctttt ttcaaattct gttagcaact tggtaccgat
    53641 gccttttgtt ttcaaatcag gatttgcagc taaaaaaatg atctctccat ctggcgaatg
    53701 cttctttaaa tatgctgcaa gcatttgttc atttgctgtc tcgtaagctc ctttactttc
    53761 tttagcaaat atattttgta aaaaatcgaa tatcttaaca tatatttgct gtccaaaaga
    53821 acgatgtttc tttttttctc cttttatctc cgccagcaaa acacctgcca actcgtcctc
    53881 tgcatacaaa gcaagaattt gagttgctcg attcaactcc atatacaaaa aatatcttcc
    53941 gtaaagattc agcagaagtt cattttccat atatctctca aagttcattc cttcaacagc
    54001 aaaatagata gcttttttgt aatctttctt ttctaagggt ttaaaagtta gtttcatcat
    54061 ttcgcctcct caacttcaat gattgtgtta tacttacatt ataatagaca cagtgtctac
    54121 tatctataat caatcatcta taagtttgtc gattaagcga cagctttgct ttgatatgtc
    54181 ggataaggag ataggtaaat gaaaaagaca gatagacgcg tcaaaaaaac agaaaaagct
    54241 ttggctgaaa cactatccac attattagta aataaaaaga ttcaagcaat cactatacgc
    54301 gaactaacag aaacggcaga tgtacatcgt tcgacttttt atacacatta taaggatatc
    54361 tatgatctat atgatcaatt agaaagcaac ttttttcggg atctaaatga aattctctct
    54421 tatgatccag cccatagcta tgaggaacta tacactcgct tgattgacta tgtttacgca
    54481 aatacttttt tatatcgctt atttatcctc aaccatggtg atatttcgtt tcagaagaaa
    54541 gttaaacaag ttattgaaga aaactatctg aacatatggc tatatgaaga caagaaaacg
    54601 attatcacag aagaaatgag attctttact acgtaccacg tccaaggttg tctatccgtt
    54661 ctcaatcggt gggtagaaag caattacaag tactccaaaa aagaattatt agaactctta
    54721 cagaaactga atgatcacat agagaaaatc atgccttgaa taaaaacata ctaagcttag
    54781 ttaagaagaa ccgtaacctt ctcgtataac aactgaatct tatttagcca aattgtttac
    54841 tgaagatttt ttgagtaaaa tttctataat tcctacttat tgaaaagtag tttgtagtgc
    54901 tgcttctccc tctctaagtg atatatcttg ttgtaccaat caaattcacc tcatcattaa
    54961 taaattactt ttaggctaat ttattacaac ttataggttg aagctgtaac caatttatag
    55021 tcatattata tttttatcat ccagtttatt gaattcttct cgtttacctc aattcatttt
    55081 caaggggaat cagctcatca tctaacattt tacgccatgc tcgcttcatt tcttgtgggt
    55141 atttaaatgg tttcgcttct ggatgtttgg ctttatatcc ttcgtaatcc ttactgttga
    55201 taattgcttt catattagga attggatctt cacctggcat atattgcaga ttagaagcat
    55261 gtaatttttt ctcagaaaca aaccactcat tggaaaagac atgaatcaaa tcatcactta
    55321 cttgtgtaaa atagcgacgt ttaatgacaa agatatcttc attgctatct agtgtacctt
    55381 catttctttg tgcttaaatt caaagataat tttctcaata aagatttttg attccagtaa
    55441 gattccttta ctccttttac aacatagcgt tgtcctttgt tttgaaacat cttcttcccc
    55501 tctttgccat taaaaatagc ccaattctct ataaagaaga ttaagcttca ttattataat
    55561 ataaagttta aatttggttt attacttact ttttcttatt ctctagtaag ctaatattga
    55621 aaaaaatgta atcagatcat tatttttata tgttgtaact tcctgataag aaaactaatt
    55681 aaaagaaaga ggtaactaca taaactaatt aaaaaagcta acttcatagt tggaggataa
    55741 atggaagaaa cttcaatgat tgtttctcct tgtgttcctt caatcgacac tagtcctatt
    55801 atcaatctct cttttttgtc catttacttt tgcgactgtt ccccaataat caaatacagg
    55861 aagcgttatt ttttgtcctt tagattcatg tactgtatag actattttcg aatccatcac
    55921 ttgataaggc atagtatgcc attccttgcc aattcttact tcatgattct gcaaatgttc
    55981 tttgtattgt aatgcttccg tgggtgcata gtcataaagt cctccgggaa ggagtgtcgt
    56041 gtaacgaata agattttctt gattcattac caagtgatct ctctgagtga caactttatg
    56101 ttcatagttt gcttttgttg cagcagatac agccaacagt aataaaacaa ttgccgttat
    56161 attaactact tttctttgct tagctgatgt gctcttcatg aaaacgaacg ataaaatcaa
    56221 cgagccaaac agtacttgaa agcctaagat tcgccaagga aattgaatca tttgaatggg
    56281 tgtattttgt aataaagacc atggaaaaaa tttggtggat aagagccaag agactaccgc
    56341 actaaggtaa atcacttttt ctttgcgatt aaatccttta aaaaagaaga gtggacagat
    56401 caaagaaata ataccaatga ttcctaccgt aaaggttgtc aggtcattat tcatcgcacc
    56461 aatcaaacta tccgagacat ttaatgcttg gtgttgtaag gtcgttttat ctggctcatt
    56521 aatcgattga accatgattt gtcggaacat cggataccaa aagtatgctg ttaaaagaat
    56581 cgtcattcct actgcctttg acaactccac aatcaaccgg atgctttctt tttttcttgt
    56641 ttcacttact acaaagccgc ctaagactag taagccaacg gctattacac tcataaaagt
    56701 ggaaagaaca tgtgtataaa tgagtaagct catactgact gctaatggaa ttgcacatgg
    56761 ctttttctca taaatcagtg cgtaagcata atacataact atcggtataa ccgtaagtgc
    56821 aatcgcttca gcaatagcag aacgatgata aatatcaatc gtacggtacc cataaaatgt
    56881 atataaacag ctaaatataa aagccgcatc gattcttttt aaaaatttta gtccataatg
    56941 aaacatcagc atgatagtac aaacattcaa tagccaaaca tataagatat aactaacgat
    57001 taaattatta cttatccaat aaaaaatgac tgccggaaaa aaggtcaagt agggataaaa
    57061 ataattcact ccgctcccat aatgattaaa cgtcgtaaaa ttgattggac cagaaaaaat
    57121 tgaagataac cctttgactc tagcaaaatg gaaggcaata tcccccgatg tagaaatagt
    57181 atgaacattt ctaaaataat tgattgaata aagtccagca ataattgcta ggagaatgga
    57241 caatattatt tttttcttta cttgcattac ttaattatat actcctttca tggattgctt
    57301 tatctagtat aacttaaatt ttaaataaat cgttatttat ttttactctc acttaaaaaa
    57361 gcactaaaat tataagagag ggaggtaatg gtctgaacac caagaattgt tccaacatcg
    57421 aattgcttaa ctaatgagtt caaagcttaa ttatgtggct cttatattta ccgagcgtgg
    57481 attgcgatct ctttagcgaa acaaacatct ttcataaaaa aaacagccat atccgctttc
    57541 ttggatatga ctatttacta ctactttact atctttcatt cttcttgtct cacttatgat
    57601 aaggcgctgg gtatcatgag tgaatgatat tgctgaatac aaatagtccg accacattaa
    57661 gttgatcgga cttcataagc attttattga ctaatacttt tttgcttaag aattgattct
    57721 aacatctttt gctaaagtta agcatcctat agttcctgca ttatctgcta acttaggtgt
    57781 gacaatgtat tcttcgatat ttggcgtatc gacatagccg ttaattagtt ctaaaaaacg
    57841 tctttgtact ttctttttca gatgttcttg ttgcatgaca ccaccaccaa aaattataat
    57901 atctggtgaa agcatcaggg tcgtattaca ggcacattgt gcaatataat ccgcctcgat
    57961 ttcccagaac ggatcttcta tagaaagatc ttgtcccttg gttcccgtac gcatctcgat
    58021 agcgggtcca gatgccaacc cttcgagaca atcatgatga aaaggacaag taccagagaa
    58081 agtatctcct gaatgtctct taactaacgt atgccccatt tctggatggc taaacccttc
    58141 aacaaaaatc ccatcttgta tagctcctcc accaattcca gttccaacag tgtaataaac
    58201 aacactggat aaaccttttc catgacctga aacatactcc ccgtaacaag cagcattcac
    58261 atcggttgtc caggcaattg gaatttcgaa atgcttattc aacgttccaa caaaatcaaa
    58321 atttttccag gcagtttttg gagtagaggt gatatgtcca taggtctttg attcacgatg
    58381 gatatcaatc ggtccaaatg accctactcc aatgctttct aattgttctt tatagtgatt
    58441 aaagaaatca attaccaaac tcattgtttc attcggtgta gttgtaggaa aactcactct
    58501 ttctaaaacc tttaaatcat cattgccaat ggcacaaaca aatttagtcc cacctgcttc
    58561 tattgagcca tacatttctt actccaccgt ccttttatct aggaattcgt tcttccctgt
    58621 ctaatagttt ttcgaaaaac tcatgtggtt ccttttggta ccaataggca acagaagaaa
    58681 tatcgtcttg acgctcataa agcttgatgt catcatttcc tagggtttgg aaagtaacac
    58741 gtaaattttc tttgaaacta atggggtcgg gtaaatgcca gcggtacaac ccatgcatcg
    58801 gtaaagcatc atcgccaaaa ccatgaactg gatttggatt aggttttcca gcactaaaat
    58861 aatcccgggt gtgatctctt ttagattgaa aaggatagcc cataaatagc gtattaaaat
    58921 tttgagcata tgccctttct ccaaagttct ttttatggaa agcccaagcg ccgccaaaat
    58981 aatcttctgc tcctgtagat gttattgtag ggaaatcttc atctccatct atataaaact
    59041 taaattctcc ttccccccac cagtatcttt ccaatgcgca caaagcaaag taggttccta
    59101 cataataccc agtgcctttg attccatcaa taagggtgta atcttttcct tttgtcgtga
    59161 tgggttcacg gttccattta gcatgaaaat acatcgcatc atccggtact tcagtcaatg
    59221 cataattaaa tgtataaaaa atgtgcttaa taaactcagg atgttcattc gttaaagtaa
    59281 tcttagcttt ttttcgaaat ggcatctcaa aatagcaatt catccctgat gttggattca
    59341 ctacgattgg taaggaattc acttcgcatc ttgtcccaaa cccattacaa aaaaaatctc
    59401 ctaatggact ttctacagaa ggagtggatt catcatccca ataaatacgc aaaattaaat
    59461 cacgtaagac gaaactccca gcgattgttt tgtctgtcac tgtcatccaa aaatgacgta
    59521 aaattccagg gccttccatt tctgctaaag taattgtctc tccagcattt atcggaacag
    59581 aaggtgaccc ttttctccca attcctagat gactcgctgt cattgccgct ttcccttttt
    59641 caccattttt attttctggt gaaatagttc tactttcctc tcccttgtgg agccatatat
    59701 tatttaaaca attcatttta ttcgtcctct atcctttctt cacttttttg attattcata
    59761 tagatgattt gttgttgtgc ctccgcaata attgctccaa tatctaaatt atcatttcct
    59821 aactgcaaag cgattgacat tgccaaggga agattcattc ctgcaattac gtgcactctg
    59881 tcagaaatat aggtaaaaaa cttttgattt acacttcctc cagccatgtc agttaaaaca
    59941 attatttcgt ctgtagtatc cactaactct ttaatttgtt catctatatc atcaatttct
    60001 tcgacatatg cacataagct actaatttga ttatgcatac ctgttaaaaa ctctagtgtc
    60061 tctttaaaac cctcagctag tattgaatgg ctagcaatga tcaatcttct cataattcaa
    60121 atccttttcc tttacgctaa tattccaaat gcagccataa ccatcgcaaa aacaataacg
    60181 agtagaatca aaatggtcat actgattttt ttcttactga gtagataata tgctgcagca
    60241 gtaataatta ctggaattaa tgttggtaaa attttgtcca acattggttg gattttcata
    60301 ctaacttcac caaaagtgaa tttaagtggc gttgaaacac tgataactga agcaattaat
    60361 gatccaacta ctgttagccc caatactgaa gcagcttcag ttaaataatt aatcttttca
    60421 ccgtattcag taacaatctt cattccctgc ttataaccaa attcaaagcc tctcattcgg
    60481 aaaaagaaga ttaccatgat taaaatgaac cataaaaaga ttcctacagg attattttct
    60541 aaagccatat aagccgcaat tgatcccatg atggttggga tcatcgtcat caaaagagag
    60601 tccccaatac cagcaattgg acccatcgta ccaactttaa agtcattaat cgcatctttt
    60661 gcttctaatc cttgcttttc ctccattgca acacaagcac ctaaaataat ggctgccagc
    60721 caaggctgtg tattgtaata ctgaaagtga ttatttaaag cttcgatgta ttcatcatca
    60781 tctttgtata attttcttaa aataggtgac aatgcgtaag tcacagatgc accttgctgt
    60841 gtttgataat taaaggtaca aactgacatc aaccaacgat agttcgcttt cctaagatcc
    60901 tttttcgtta cttgatattt ttcgctcatt ttattcatcc tccccaataa acccaacatc
    60961 agaagctccc gcagaagcag tgatttgtgc atctttttca gctctatgat acacattaaa
    61021 tgctaaagcg aatcctatga tcgccgctcc aataataggt accttcaaaa aagcggctaa
    61081 gaaaaatcca acaagtaaat aactaatgta tcgacctgta ggcataaagc gtaacaacat
    61141 cgcaatacca acagcaggca acatttttcc ggctaatgtt agcccatcca taaaccaatt
    61201 aggtaaaaca tccaaaacgt aattaacagc agactgtcct aaagtaacgg caataaatac
    61261 tggaattgct gcagataaac caaagaaaat tggccccaac cacaaaacac tattcatttt
    61321 cttaaattct cgtttattcg catattcctg tgatttgcga acaacaaaac catttaagat
    61381 tttgacaatt acatctagtt gcacccctaa catacctaca ggtagtccta ttgctaatcc
    61441 ggcttctact ccaagctggc taccaaatgc cgttgcaata attgcgcacg ttccatagtc
    61501 cggtacagat gagccaccaa aaccggcaac tcctaatgac atcaattgaa ctgtaccgcc
    61561 aactatcaaa cctgttttta tatcacccat caaaattcct gtgaataatc cccaaaaaac
    61621 tgcgtaattt acaaagatca tcggaatccc ataataatca acatgtttaa taaatgctaa
    61681 tatagtcagc ataataattt gaaaaatagt aaaatgcatt atccttactc ctttatccta
    61741 attttgattg aatttcctgt gccttatccg ccggaacaaa ttgtgtaaca atttctacac
    61801 cagaatccaa caatttttta tacgtgctga tattttcatc tgatgcatag gctctagaag
    61861 atagctgtaa tgcattatct ttaacaacag taccgccaac aattagtcgg tcaattctaa
    61921 taccgttatc tactaaatga aggattgttt ccggctcttt cacgatgaca aatacttttt
    61981 cctgatcgta tttccccttt ttaaaattcg caatcgctgt ttcttcagtg ataattgata
    62041 cagccattcc agcaggtcta gctaaacgca tacttgattt ttggatgtcg ttatttgcga
    62101 cagaatcatc gatcaccatc actctgtttg ctttagacat tggtgcccat tgcgtgacaa
    62161 taatcccatg caataaacgg ttatcaactc tcgacataac aatactcata aatacttcct
    62221 cctttatctt tcattttctt acaagcaatt accatgccaa aacaaaaaga acttgataaa
    62281 tcaagctctt tttacataat cataaacgta tttaacctca tgaatcggga tgtcgacact
    62341 ataataatgt tcaacgacac tgaaagattg cttaaaatgt gtctgaaatt tttgaaattc
    62401 ctcactcgtt tcattgaaat aaatttcatc ttccaaagta ttttgtttta ctaatcgttc
    62461 aattaagcaa ctaatgtgaa catataatcc gaaacacgta ttattatcaa atgaaattcc
    62521 tagatcattt tgtaagatgt atatagcatc tgaaacccgt tctaataatt tagtcggatt
    62581 taatatggtc aattgctcca ttaaattcgt tagactaaaa ttcttcagaa tattattgtt
    62641 caaaactttc agttcattat cattaaagtg tctattcaat tgattggaga atttacttat
    62701 attcattcct aaaatcatat cttcaattga aaagaattct acatcttcta gatgtggatt
    62761 tagtgttcca acaataaaaa gaatattgtt ctctttacga agctccgata aatagttttc
    62821 attcactaaa gagtaatagt cacacgtttc tatgacaaga tcagtatccc ttggaaagct
    62881 atcttcaagt atccttttta atttaaacga agttcctaat ccgcttgcac aagaacagac
    62941 aatcatatcc ttcttaatat ttgatgattc ataaatataa tccacatttt gattttcttt
    63001 tacttgttca agaatctgtt taagcggtaa atctaataat atctgatttg caacatcaat
    63061 agccattctt gttgaaacat tgtttagtag tccgaatttt ttttgagcgt ctagttccaa
    63121 atttagataa attttctcca gtgaacccat atcaacaagt aaaataattt cttcatatcc
    63181 ggtacactct tgtaagtatc tattaatttt gtctgcaatc tcactacttg aagtcattag
    63241 tggcatatca atggcgtcgt atatatatct ctcaacgatc ctattagcag tacttgctat
    63301 acaggttgcc gttagatctc catgagccaa aatcagtgct aaacgttttt gctgaaattc
    63361 tttactacac attaacttaa ataaaataac caaaacattt ttttgaattt ttgttaaata
    63421 aatatcccct atttgaataa aacgattgac taattgaact tctcgactac accaactatt
    63481 aatatcattg atgaaggaat ataatttatc gtccgatgtt aattggattt gataaatcca
    63541 agaattcaaa aagatagacg ttatttgaag ataataatag tcaaattcta tttgaaaatc
    63601 tctctctatt tccttaacat actgtctaaa tcgaatctct tgataggtgg gatatgttaa
    63661 agctgaatta ttttggatat caacattctt ttgtctaaaa tatctatcat atttctcaaa
    63721 aagctgctgc ttatcagtgt ctttcttcca cgtttgataa agatactcta taagttcgtt
    63781 gatattaaaa acttcgtcta ctttttccaa atcatccatt tgaatatatt ttaattcatt
    63841 ctgtcttttc ataaccttca tgccgttgaa attcacccat tgtggtaaat gatacatctg
    63901 aatataaagt tcttccaaat catctaagaa ataaaaggca ttggcacagg tcaattgaat
    63961 gatatttttc aaattgccaa cattttcact aaagcgatag tttaataaaa aatctaataa
    64021 ttgttgagat atcagtattt tctttgctag tctttcttct tctgatttaa aaaatatctt
    64081 gattaactgt tttctttcat aaagagaacg actgtctaat gttggaagtg ttagctttac
    64141 aggtattctt ctcaacaaag ttgataatag tttatcctca ggtggttctg atgttgcaaa
    64201 tataatccag caacttgatg tgtaccagtt ttcattatca cccatccgat gaaatttcct
    64261 cgtatccata aactgaaaaa gtttctcctg acattcattg ctcaatgcat gaatttcatc
    64321 taaaaataag actccattat tagctaattc tgctaaaccc tttcttccat cttcggctcc
    64381 tgtatatgca ccttttacat gcccaaaaaa attggacaag aaaagttctg gattattggc
    64441 atattcacta caattaactg aaatgaaaga tgccttctct tctatataat tattggccaa
    64501 caaatcctta tacacataat ttgctaaata gctttttcca gttccagtct cgccatgaag
    64561 taaaatgggt aagccatttg gcggatagta gattgctgct ttaatttgag caattacatt
    64621 tcgcagactt ccttgacttc cgataaccct ttctattcca accctaaaag agctatcata
    64681 ccatttttcc gcttcctctg aagagctaaa aatttgttga tttggaactt tctccggtaa
    64741 agaaaagaag attactggac gagtattgat ttttccaaat tctccatctt ttacgaattc
    64801 attcaaatat tgagagacaa tattacgact aacatttaat ttttcagata ttttctgtgc
    64861 tgtattgttc ccccatttat ttttaatctc agagttctct atgacataat tgacaatgcg
    64921 ttcttttaat tcttccatca cagcacctcc tcgacactat tcgaattttg ccgacagtat
    64981 ttttccataa atatgacttg ctaaaaaggc tttgtttaga tcattcaatt ggaacgttgc
    65041 ttgttttgct tgatccgcta agacgttgaa aagatactct ggcgaaatcg cataccccaa
    65101 aatatcaacg attgttgcaa tcagatcttc ttttgattct tcatctgaaa gtaattcacg
    65161 atacaacatc gtttgtttgc ttactgtgtc atattcctct aaggattcat ctgctaaaag
    65221 aaccacttgt tccaacaaac ggtcggataa atatttatag aaaatcagcc ccaataaata
    65281 atttttatat tctgacgcat ccattttact acggagatta tctgccgcac taaataactt
    65341 ctgatttaat tctgcaccca aaaagataca ctcctatctc ttatttaaag ttgctatata
    65401 ccctcttatt ttagcatact cagttttaga aaaagcaaaa aaataaagaa acttattctt
    65461 gataacaagc tacgtgacgt atatccctaa cacaaaaata gccatatcct ttggtttgga
    65521 tacggctatt tgatattact cattcaatta tcaaatcaca gtaggtgtga atctcatcgg
    65581 gatcggcaat atctacttct gattaggatc aaaggtgatt ttctcaataa aggtgtgata
    65641 caaagcttta acttgcttct tctcactctg gataagaaag caatccaaac tagtcaatat
    65701 ctgttggaca tctttgactt gaatcggttc cccttgttgt tgaaagatcc ctaagatttc
    65761 attctctcga atttgtaact gtcttcgttt ttcagtcaat tcatttaaac gatcttttaa
    65821 catcggaaac aattcgggac tatcttccaa agcagcttcc tgtttttgct ctaatagtta
    65881 gattttgcgt accattttct tcttttattt tccttcgatt gctgatttta atatagtcta
    65941 aaggaaattt atatttattg tattctttat aacttcaaga gaacttcgtt tgagtattac
    66001 tgtatttttt taattccata agaaaattag ttattacctg ccacctaatc agcaaatctg
    66061 aacctgagtc aatataatta atattatttt ccatctccaa cattgtaagt actgttggtg
    66121 ttaatatagg gactttgtac aattgtattt ttttgatttt atcatctgca caaaggagat
    66181 tttttaaatc taatccttct tttatttcaa aagttgaatt ttttaaatct ataagagtaa
    66241 aaccaattcc ttcatactga atttctgaaa atcgaatttt tctcccagtt gatagatcaa
    66301 ggggcagaaa accttttatt acattgtgag tgtcaccatc atttacaatg tcattaggaa
    66361 ttttgatttt agaattctgt ggagcaccta ttggaagata ataattcatt ataattttgt
    66421 agtcttcatg aggaaataaa gtacttttag gattgctaag atattctcgt accgaatcta
    66481 agaatggctt atccattgaa tcttcatccc catttaaact aaaaaacatt cctacaattg
    66541 cttttgcaac tctaagtgaa ttcattttct ttattgaatg tgttaaatca gacttaccat
    66601 tctttaaact tgtattgtta taaaggaaat ttttattgtc ttctgcaaat ctaatatatt
    66661 cctcaacata ctcactacca aaaaaactat tacatttact acataacgta ttggaatggc
    66721 aacagttttt ttgacaaatt ttataaggtg cagaacttct ttccgtatgc tattccgatt
    66781 gtccttgaca atgagcctcc tcggatgtga cgatcttcgg caggagctaa cagttaaagt
    66841 tagactgcct cgctagcgtt agcacatccg agctcattat caaggattcg ctgcgccaat
//
LOCUS       DBBGSP010000009        65479 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000009 DBBGSP010000000
VERSION     DBBGSP010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 65479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.009"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            166..1029
                     /locus_tag="ACIZE9_000681"
     CDS             166..1029
                     /locus_tag="ACIZE9_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGC6092567.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1158..2780)
                     /locus_tag="ACIZE9_000682"
     CDS             complement(1158..2780)
                     /locus_tag="ACIZE9_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGC6092568.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3029..3550
                     /locus_tag="ACIZE9_000683"
     CDS             3029..3550
                     /locus_tag="ACIZE9_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HGC6092569.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(3736..5466)
                     /gene="spxB"
                     /locus_tag="ACIZE9_000684"
     CDS             complement(3736..5466)
                     /gene="spxB"
                     /locus_tag="ACIZE9_000684"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGC6092570.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5631..6449
                     /locus_tag="ACIZE9_000685"
     CDS             5631..6449
                     /locus_tag="ACIZE9_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HGC6092571.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6552..6749)
                     /locus_tag="ACIZE9_000686"
     CDS             complement(6552..6749)
                     /locus_tag="ACIZE9_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092572.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            6918..7496
                     /locus_tag="ACIZE9_000687"
     CDS             6918..7496
                     /locus_tag="ACIZE9_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HGC6092573.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7591..7728
                     /locus_tag="ACIZE9_000688"
     CDS             7591..7728
                     /locus_tag="ACIZE9_000688"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092574.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8541..9044)
                     /locus_tag="ACIZE9_000689"
     CDS             complement(8541..9044)
                     /locus_tag="ACIZE9_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGC6092575.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9403..10428
                     /locus_tag="ACIZE9_000690"
     CDS             9403..10428
                     /locus_tag="ACIZE9_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HGC6092576.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            10751..11629
                     /locus_tag="ACIZE9_000691"
                     /pseudo
     CDS             10751..11629
                     /locus_tag="ACIZE9_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
     gene            12105..12221
                     /locus_tag="ACIZE9_000692"
     CDS             12105..12221
                     /locus_tag="ACIZE9_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HGC6092577.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13149..13487
                     /locus_tag="ACIZE9_000693"
     CDS             13149..13487
                     /locus_tag="ACIZE9_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092578.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13581..13811
                     /locus_tag="ACIZE9_000694"
     CDS             13581..13811
                     /locus_tag="ACIZE9_000694"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HGC6092579.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14211..14582
                     /locus_tag="ACIZE9_000695"
     CDS             14211..14582
                     /locus_tag="ACIZE9_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HGC6092580.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(14856..15548)
                     /locus_tag="ACIZE9_000696"
     CDS             complement(14856..15548)
                     /locus_tag="ACIZE9_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6092581.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSYEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15551..16336)
                     /locus_tag="ACIZE9_000697"
     CDS             complement(15551..16336)
                     /locus_tag="ACIZE9_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGC6092582.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16573..17973
                     /gene="lacG"
                     /locus_tag="ACIZE9_000698"
     CDS             16573..17973
                     /gene="lacG"
                     /locus_tag="ACIZE9_000698"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGC6092583.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            17998..18315
                     /locus_tag="ACIZE9_000699"
     CDS             17998..18315
                     /locus_tag="ACIZE9_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGC6092584.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18328..20001
                     /locus_tag="ACIZE9_000700"
     CDS             18328..20001
                     /locus_tag="ACIZE9_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HGC6092585.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20015..21646
                     /locus_tag="ACIZE9_000701"
     CDS             20015..21646
                     /locus_tag="ACIZE9_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HGC6092586.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22137..23702)
                     /gene="guaA"
                     /locus_tag="ACIZE9_000702"
     CDS             complement(22137..23702)
                     /gene="guaA"
                     /locus_tag="ACIZE9_000702"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGC6092587.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(23761..24684)
                     /gene="coaA"
                     /locus_tag="ACIZE9_000703"
     CDS             complement(23761..24684)
                     /gene="coaA"
                     /locus_tag="ACIZE9_000703"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGC6092588.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            24880..25485
                     /locus_tag="ACIZE9_000704"
     CDS             24880..25485
                     /locus_tag="ACIZE9_000704"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6092589.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            25793..26809
                     /locus_tag="ACIZE9_000705"
     CDS             25793..26809
                     /locus_tag="ACIZE9_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6092590.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            26950..28251
                     /locus_tag="ACIZE9_000706"
     CDS             26950..28251
                     /locus_tag="ACIZE9_000706"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGC6092591.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28297..28959
                     /gene="deoC"
                     /locus_tag="ACIZE9_000707"
     CDS             28297..28959
                     /gene="deoC"
                     /locus_tag="ACIZE9_000707"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGC6092592.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            28980..29378
                     /locus_tag="ACIZE9_000708"
     CDS             28980..29378
                     /locus_tag="ACIZE9_000708"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGC6092593.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29444..30526
                     /locus_tag="ACIZE9_000709"
     CDS             29444..30526
                     /locus_tag="ACIZE9_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6092594.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            30738..32300
                     /locus_tag="ACIZE9_000710"
     CDS             30738..32300
                     /locus_tag="ACIZE9_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092595.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32293..33426
                     /locus_tag="ACIZE9_000711"
     CDS             32293..33426
                     /locus_tag="ACIZE9_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092596.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33426..34382
                     /locus_tag="ACIZE9_000712"
     CDS             33426..34382
                     /locus_tag="ACIZE9_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092597.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34481..35647
                     /gene="deoB"
                     /locus_tag="ACIZE9_000713"
     CDS             34481..35647
                     /gene="deoB"
                     /locus_tag="ACIZE9_000713"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGC6092598.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35671..36489
                     /locus_tag="ACIZE9_000714"
     CDS             35671..36489
                     /locus_tag="ACIZE9_000714"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGC6092599.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36506..37213
                     /gene="deoD"
                     /locus_tag="ACIZE9_000715"
     CDS             36506..37213
                     /gene="deoD"
                     /locus_tag="ACIZE9_000715"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGC6092600.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37511..38197)
                     /gene="gpmA"
                     /locus_tag="ACIZE9_000716"
     CDS             complement(37511..38197)
                     /gene="gpmA"
                     /locus_tag="ACIZE9_000716"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HGC6092601.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38369..38950)
                     /locus_tag="ACIZE9_000717"
     CDS             complement(38369..38950)
                     /locus_tag="ACIZE9_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6092602.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39083..39766)
                     /gene="rpiA"
                     /locus_tag="ACIZE9_000718"
     CDS             complement(39083..39766)
                     /gene="rpiA"
                     /locus_tag="ACIZE9_000718"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGC6092603.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40085..40498
                     /gene="rpsL"
                     /locus_tag="ACIZE9_000719"
     CDS             40085..40498
                     /gene="rpsL"
                     /locus_tag="ACIZE9_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGC6092604.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40582..41052
                     /gene="rpsG"
                     /locus_tag="ACIZE9_000720"
     CDS             40582..41052
                     /gene="rpsG"
                     /locus_tag="ACIZE9_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGC6092605.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41146..43233
                     /gene="fusA"
                     /locus_tag="ACIZE9_000721"
     CDS             41146..43233
                     /gene="fusA"
                     /locus_tag="ACIZE9_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGC6092606.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43405..44592
                     /gene="tuf"
                     /locus_tag="ACIZE9_000722"
     CDS             43405..44592
                     /gene="tuf"
                     /locus_tag="ACIZE9_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGC6092607.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            44999..45307
                     /gene="rpsJ"
                     /locus_tag="ACIZE9_000723"
     CDS             44999..45307
                     /gene="rpsJ"
                     /locus_tag="ACIZE9_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGC6092608.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45338..45967
                     /gene="rplC"
                     /locus_tag="ACIZE9_000724"
     CDS             45338..45967
                     /gene="rplC"
                     /locus_tag="ACIZE9_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGC6092609.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            45995..46618
                     /gene="rplD"
                     /locus_tag="ACIZE9_000725"
     CDS             45995..46618
                     /gene="rplD"
                     /locus_tag="ACIZE9_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGC6092610.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46618..46908
                     /gene="rplW"
                     /locus_tag="ACIZE9_000726"
     CDS             46618..46908
                     /gene="rplW"
                     /locus_tag="ACIZE9_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGC6092611.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            46947..47780
                     /gene="rplB"
                     /locus_tag="ACIZE9_000727"
     CDS             46947..47780
                     /gene="rplB"
                     /locus_tag="ACIZE9_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGC6092612.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            47823..48101
                     /gene="rpsS"
                     /locus_tag="ACIZE9_000728"
     CDS             47823..48101
                     /gene="rpsS"
                     /locus_tag="ACIZE9_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGC6092613.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48124..48471
                     /gene="rplV"
                     /locus_tag="ACIZE9_000729"
     CDS             48124..48471
                     /gene="rplV"
                     /locus_tag="ACIZE9_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGC6092614.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48485..49141
                     /gene="rpsC"
                     /locus_tag="ACIZE9_000730"
     CDS             48485..49141
                     /gene="rpsC"
                     /locus_tag="ACIZE9_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGC6092615.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49144..49578
                     /gene="rplP"
                     /locus_tag="ACIZE9_000731"
     CDS             49144..49578
                     /gene="rplP"
                     /locus_tag="ACIZE9_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGC6092616.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49568..49756
                     /gene="rpmC"
                     /locus_tag="ACIZE9_000732"
     CDS             49568..49756
                     /gene="rpmC"
                     /locus_tag="ACIZE9_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGC6092617.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            49781..50047
                     /gene="rpsQ"
                     /locus_tag="ACIZE9_000733"
     CDS             49781..50047
                     /gene="rpsQ"
                     /locus_tag="ACIZE9_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGC6092618.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50105..50473
                     /gene="rplN"
                     /locus_tag="ACIZE9_000734"
     CDS             50105..50473
                     /gene="rplN"
                     /locus_tag="ACIZE9_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGC6092619.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50510..50818
                     /gene="rplX"
                     /locus_tag="ACIZE9_000735"
     CDS             50510..50818
                     /gene="rplX"
                     /locus_tag="ACIZE9_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGC6092620.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            50846..51385
                     /gene="rplE"
                     /locus_tag="ACIZE9_000736"
     CDS             50846..51385
                     /gene="rplE"
                     /locus_tag="ACIZE9_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGC6092621.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51404..51589
                     /locus_tag="ACIZE9_000737"
     CDS             51404..51589
                     /locus_tag="ACIZE9_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HGC6092622.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51625..52023
                     /gene="rpsH"
                     /locus_tag="ACIZE9_000738"
     CDS             51625..52023
                     /gene="rpsH"
                     /locus_tag="ACIZE9_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGC6092623.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52055..52591
                     /gene="rplF"
                     /locus_tag="ACIZE9_000739"
     CDS             52055..52591
                     /gene="rplF"
                     /locus_tag="ACIZE9_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGC6092624.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            52752..53108
                     /gene="rplR"
                     /locus_tag="ACIZE9_000740"
     CDS             52752..53108
                     /gene="rplR"
                     /locus_tag="ACIZE9_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGC6092625.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53129..53629
                     /gene="rpsE"
                     /locus_tag="ACIZE9_000741"
     CDS             53129..53629
                     /gene="rpsE"
                     /locus_tag="ACIZE9_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGC6092626.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53644..53823
                     /gene="rpmD"
                     /locus_tag="ACIZE9_000742"
     CDS             53644..53823
                     /gene="rpmD"
                     /locus_tag="ACIZE9_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGC6092627.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            53867..54307
                     /gene="rplO"
                     /locus_tag="ACIZE9_000743"
     CDS             53867..54307
                     /gene="rplO"
                     /locus_tag="ACIZE9_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGC6092628.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54307..55602
                     /gene="secY"
                     /locus_tag="ACIZE9_000744"
     CDS             54307..55602
                     /gene="secY"
                     /locus_tag="ACIZE9_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGC6092629.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55664..56311
                     /locus_tag="ACIZE9_000745"
     CDS             55664..56311
                     /locus_tag="ACIZE9_000745"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGC6092630.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56502..56720
                     /gene="infA"
                     /locus_tag="ACIZE9_000746"
     CDS             56502..56720
                     /gene="infA"
                     /locus_tag="ACIZE9_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGC6092631.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            56753..56869
                     /gene="rpmJ"
                     /locus_tag="ACIZE9_000747"
     CDS             56753..56869
                     /gene="rpmJ"
                     /locus_tag="ACIZE9_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGC6092632.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            56887..57252
                     /gene="rpsM"
                     /locus_tag="ACIZE9_000748"
     CDS             56887..57252
                     /gene="rpsM"
                     /locus_tag="ACIZE9_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGC6092633.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57280..57669
                     /gene="rpsK"
                     /locus_tag="ACIZE9_000749"
     CDS             57280..57669
                     /gene="rpsK"
                     /locus_tag="ACIZE9_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGC6092634.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            57749..58687
                     /locus_tag="ACIZE9_000750"
     CDS             57749..58687
                     /locus_tag="ACIZE9_000750"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGC6092635.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            58715..59095
                     /gene="rplQ"
                     /locus_tag="ACIZE9_000751"
     CDS             58715..59095
                     /gene="rplQ"
                     /locus_tag="ACIZE9_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGC6092636.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59367..60206
                     /locus_tag="ACIZE9_000752"
     CDS             59367..60206
                     /locus_tag="ACIZE9_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC6092637.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60182..61051
                     /locus_tag="ACIZE9_000753"
     CDS             60182..61051
                     /locus_tag="ACIZE9_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC6092638.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61041..61838
                     /locus_tag="ACIZE9_000754"
     CDS             61041..61838
                     /locus_tag="ACIZE9_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGC6092639.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62041..62787
                     /gene="truA"
                     /locus_tag="ACIZE9_000755"
     CDS             62041..62787
                     /gene="truA"
                     /locus_tag="ACIZE9_000755"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGC6092640.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            63451..63645
                     /locus_tag="ACIZE9_000756"
                     /pseudo
     CDS             63451..63645
                     /locus_tag="ACIZE9_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(63833..64609)
                     /locus_tag="ACIZE9_000757"
     CDS             complement(63833..64609)
                     /locus_tag="ACIZE9_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGC6092641.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            64732..65139
                     /locus_tag="ACIZE9_000758"
     CDS             64732..65139
                     /locus_tag="ACIZE9_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HGC6092642.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT        20826 a        11652 c        13803 g        19198 t
ORIGIN      
        1 caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac aacctcttat
       61 tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag agatttgcta
      121 taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta tcaaattgta
      181 acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt tgatttttta
      241 tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa gacattcaat
      301 tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc acaaatcaat
      361 gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc tgttttatat
      421 gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc ggttgaattg
      481 ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc tgcaagtatt
      541 ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa aagcatcgaa
      601 gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt aacagtagac
      661 gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac tcttggcagt
      721 ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac gaatgttgac
      781 aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt aaaaacaatc
      841 gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga gagcgcggag
      901 aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct ttatccctta
      961 ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc gatgggaatc
     1021 agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg taacaaaaac
     1081 agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt tttttatttt
     1141 ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat atctgcattt
     1201 tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc cgaaacggca
     1261 atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa taagattgag
     1321 ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc taaatggttc
     1381 gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga aagcatgcaa
     1441 cggactttct ctccaccaga taaaacattc actggtttca atacttcttc accagaaaac
     1501 aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt acttgcatat
     1561 tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt atcctttggt
     1621 aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg cgtaatttca
     1681 cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac gaaagcgacc
     1741 ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc atcaatcgtt
     1801 acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg tttgaatcca
     1861 acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt ttcaagcatt
     1921 tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg ggcaataaat
     1981 tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg aagtttagcc
     2041 gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt gattttacca
     2101 aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc atgggataca
     2161 acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat cgattggata
     2221 tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa tagtgtttgt
     2281 gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg atggtgcaat
     2341 tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc ttcccatcca
     2401 ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc gtcagtgaaa
     2461 tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg cttgtgtccc
     2521 atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg tttcaatacg
     2581 gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag atcccctgat
     2641 aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc atagcagttt
     2701 ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa gtgcaaactc
     2761 acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt ttgacaagtc
     2821 ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt ctttgtgttt
     2881 cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc tactatagga
     2941 tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt actataaaac
     3001 tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg actggggctc
     3061 attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag accctgtcgg
     3121 aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag ggatatttga
     3181 actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga tgcccttaat
     3241 aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg gtgcaggagt
     3301 cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt tagcgttatt
     3361 tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga tcatcgtcaa
     3421 tattttagga attttattag gaattttctt attgtttaat ccaatttctt ctgcgttgac
     3481 attaagcttt ttagttggat tctattttat gttatttggt atcacacata tcgtctatgc
     3541 atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag ttttactgtt
     3601 gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt tttaggtgtc
     3661 gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct taatactcga
     3721 agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg gcaaatcatg
     3781 gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc ttggatctaa
     3841 atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga ttactacagg
     3901 acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt ctgtgactgt
     3961 aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt ctaaaaatac
     4021 accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa aagaatcatt
     4081 cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga tatcttgcat
     4141 gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg ggtagcttag
     4201 ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc cagatgtcgt
     4261 atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg tgttaccgac
     4321 atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat agacagcctc
     4381 tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta cccatttttc
     4441 tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc ctaactcgac
     4501 aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt catggcgtcg
     4561 tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat taaaaaatgc
     4621 acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg ccaatgcttc
     4681 atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat aatcatcagg
     4741 aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt ctgagaattc
     4801 tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg gtttttttgc
     4861 tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata tcacacttgt
     4921 tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac caagatcaac
     4981 agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg cttcatctac
     5041 tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa catctgcgaa
     5101 aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag aagcaacttg
     5161 tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac cattgatcaa
     5221 atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg ttaattttgc
     5281 atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt agttgatttc
     5341 ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg gaatgccgta
     5401 aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg cattgatttt
     5461 tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta tctagagtat
     5521 agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta gtcatgtttt
     5581 tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc atggttgaat
     5641 ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt acttatttta
     5701 tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa gaagtgctaa
     5761 acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg tctttgttag
     5821 atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt gtaagtattg
     5881 ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc catatgcatt
     5941 ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg atcttgcttg
     6001 ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta gcattcggtg
     6061 cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg gtggcgctag
     6121 gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg cgacaagaag
     6181 gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt gaaccaattg
     6241 ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct tatgcacttg
     6301 cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct gaagcacagc
     6361 agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga tttatcatta
     6421 tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata tatcaaatag
     6481 ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa tgaagtgaat
     6541 ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca gcgaacaagc
     6601 cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag cccgcttagg
     6661 acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag aaccatgaag
     6721 atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca ttctttacta
     6781 tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg atttttactt
     6841 catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa aatagagcgg
     6901 aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat gctgtaatcg
     6961 cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac acgtgggagg
     7021 cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc attttagcga
     7081 tttattggaa caatcatcat catttatttc aagttgtaca taagataaat ggacgggtct
     7141 tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca acttcatgga
     7201 tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt accttgaccg
     7261 ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa ggccacgaga
     7321 aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt ggtttgaatg
     7381 tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc gcaaacatcg
     7441 tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat cggtaaaatg
     7501 atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat caaatatccg
     7561 agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca tgtaggactg
     7621 attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac ttggacagta
     7681 gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac atctttatgt
     7741 aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt ctgttgtaaa
     7801 cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa tagatagtta
     7861 gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc aaagaagggc
     7921 gtatagattt cttttgatag gagatataca acagaaatga ataaatatta acgtgttttc
     7981 aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca ttttacactt
     8041 ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag atttctctac
     8101 tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag gatcaggcag
     8161 aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc atagaaaata
     8221 taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg agtagggtat
     8281 aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg ttaagatttt
     8341 aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag cctgtcagtt
     8401 tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa atagattttt
     8461 ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt gtctattacg
     8521 gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa taaaaaagct
     8581 acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc taacttattt
     8641 gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc tcctgttgta
     8701 ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg aatcaattct
     8761 gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag tctcttgaaa
     8821 ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt ggtctcacgt
     8881 aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac attgctgtaa
     8941 gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa ccataataga
     9001 aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat ctcctccatt
     9061 taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag tttaaggacc
     9121 aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg tttctttaac
     9181 aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca aaacgactcg
     9241 gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac taagtttatg
     9301 aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg gcatttcatc
     9361 ttggttcagc tttttttcca attactagga aggagggata gattgttcaa gacttatttt
     9421 cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct acttatcttt
     9481 attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt ttcatcatta
     9541 gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct gaaacgtatg
     9601 tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc gacttatgtt
     9661 ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt cgtgttgcga
     9721 ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc catgggaacg
     9781 agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt tatgggtgtc
     9841 gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc tgagcagaca
     9901 attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat cattgattct
     9961 gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt gaatctgcat
    10021 aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa cttggatgcg
    10081 atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg tgtgtcggca
    10141 ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac ttttctatat
    10201 ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt tcttaatccg
    10261 atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt gatcgaatat
    10321 cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg ggtaatgacg
    10381 gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa ggacaaatat
    10441 atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa ggtgttcaaa
    10501 agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa ctttcaaaaa
    10561 aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat aaactttcct
    10621 gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata gaaagtttaa
    10681 gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg gataatcagt
    10741 catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga aaataagcaa
    10801 tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag agcaaatgat
    10861 tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg aactaatgga
    10921 tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag aggaaccttt
    10981 tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa tttatcaacc
    11041 attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta gatttattca
    11101 tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga tttggcatta
    11161 cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat attttccgaa
    11221 agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata ttccttccga
    11281 tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc gtttttttga
    11341 actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt tactatcacc
    11401 caatcttact aaatagttga aaaaagagtc aaaaatctgt ctttttgcag ccgattatcg
    11461 attattatca gttgatgaac aggacgatag tggagtccct tggatctttg gacgagtaga
    11521 tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa aagagcaatt
    11581 gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag tttagtactt
    11641 cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc acgctctaaa
    11701 cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa
    11761 tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc ttctgtccca
    11821 gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac tagctataac
    11881 aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa cgtaataatg
    11941 aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt ttaacaagtt
    12001 gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt tcgatttgtg
    12061 ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa aaaacagata
    12121 tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa cgtgcgctga
    12181 agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga aacttaatta
    12241 aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg tgtaaggttt
    12301 ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta gaatctttct
    12361 tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa ccacaaagca
    12421 cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa cctcttattt
    12481 tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg aaacattttt
    12541 agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt catgaaatat
    12601 ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata agcagttacg
    12661 aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa aaaaatcagt
    12721 gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg ccgaaaaaat
    12781 atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa taataagttt
    12841 tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag taataaagta
    12901 tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa ttaatggtta
    12961 aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg tgatactaga
    13021 ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa tgaaaaagaa
    13081 gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt agccaagtaa
    13141 cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt cgtgctacag
    13201 aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct agtgagccaa
    13261 ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt atggtggtaa
    13321 ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt gaaaaggtga
    13381 gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc attttaacgg
    13441 attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca ctagtgaaat
    13501 actttatgat atagaaattg atgaaaattt actagatgta gcacaagaaa tcgatcatca
    13561 aaagcaggaa gctattcgat atgctggtag aaaagggaaa agaaaatatt tattacgtga
    13621 atgtagcaaa agttagagaa gatgaaaatg agtggaaaga attcaagagt cgctactcaa
    13681 ttaactcgac tccgacattt acagtttaca gagaaggatc gatagaaaaa actgtttttt
    13741 ggactaaaga aagtggaatg tctttagctg aagtagaaga gtttttggat tatgttagta
    13801 tgcaacagta agggagttct tattatgaaa aattttgaca catattatgt tattgttttt
    13861 tcgatatctt tgctgttaat attactaact ttaatgcagt ataaagagta tccagagtat
    13921 tttattttaa cttttgtata tttagtaagt agctacacac ttctatataa attcagaagt
    13981 tcttctagag tttctaaagt ttgtttctta attagcttat tgattctata atatttttga
    14041 tttatatagg aaattaaaaa tattatagaa tcaacactca gagaacgggt tggtttttaa
    14101 tagatttaat aagtactgat aatgaaattt ctcctggttg ggaaaacgaa gttggttacc
    14161 ctgtagaaga attttttcaa gattactttg cggagtatgc cgataggata atgagagatt
    14221 acgtaacaga taaaactcaa gaagtcatca atcaatccca gtcattaaat gaattatctg
    14281 ataaggcgaa agaagaagca gttgccatta tttcttcagg gattagtgac tatattgata
    14341 tgagtggtga aatcaattat ggcgataaag acaaaattgt acgcatgata aaagctttta
    14401 tcaaaacttt tgatgtgaag gcagatctta agtttaatga tacttaccta gtaggaaaat
    14461 taattaatat ccttgggaca gagaaagata cggaaacgtt tatttcctct ttgtctatgt
    14521 tgtttacaga taagcatttt tcaactcagc ttggtggaga ggaactagtg gaaatctttt
    14581 aaccattacg cccagcatta ataaaagtat atcaaaaaag tactcctgat gatttttaag
    14641 attggtttga gaaataatgt gaaaacacta tttttaatgt taattataga tagagatgaa
    14701 cgcgtcatat ggttaaaaga atgaaaaagt caaagataca ctgctatatt tcactaagga
    14761 tatagcagtg tatctttcat gtcgtttcac tggcagtttt ttataaaagg aggtgtgcat
    14821 ttcagttgct tttctttggt agttagttga atcgtttaag aattaacgga tgtggcagac
    14881 aggtgctctg tccaaaaacc agtaaaatct ttgatggttc catctttatt tagctgtgcc
    14941 tgttcaaata ctgttttgtt tttaccgaat ggatcaattg caataattgt tccgatcccc
    15001 gcacgtttgg cagcaagtaa tcctgagtaa gcatcttcga taacaagaca atcagccgga
    15061 gctaagctca gtttgtctgc cgctttaaga aaaatatccg gttgcggttt cccagggaaa
    15121 gagccgtcgt catagacaat cttgtcccag tcaaaccagc gggctaaatc gaaaatatca
    15181 aaataaaaag caacattctc tttgacagta gccgtggcaa tcgttaatgg aatctgttgg
    15241 tcagtcagct ggtcaagagt cgcttcaagc ccttttgtca actgaagctc gttttcattt
    15301 tgcaagcaaa gcatacgata atagctttct ttttcttctg acaatacggc gatctcagag
    15361 gcggtcaaat gctctgaaat gaaatgtttc aaaatctccg tattcgtccg accatgaata
    15421 ttttttaaaa tatcctcgta tgataaacca tcttttgtat gatcatgtat catatgcagc
    15481 caagcagctt catgcagatg agagtccaaa aacattgttc cgttgaaatc aaatataatc
    15541 cctttcatag ttacgctcct atagtggtat tttcggttga atcagcaatt tgcagatcga
    15601 catattgtgc atagtgctct tgaacctccc gcgagatctg gcgatccgta atgagcagat
    15661 cgaaatcatg caaattataa aacacataaa aatcatctcg attgaatttt ttattatcaa
    15721 cgagtagata tttcttacgg gaattattta gagcgatctg ctgtgcttct ccttcttcgg
    15781 tactgtaagt agagatcgct tcgttgtgaa cgccatttga actgataaat gcttttgtaa
    15841 actttagtct tcttaaattg tcgttggtga tcggtccgac aaatgcgccg gtatttttcc
    15901 ggaaatcacc gccaatcagt agaatttctg gtccatctgc ttgagcaaga atatcaaaaa
    15961 ctggataatt atttgtaatg atccgaattt tcttgttcag taaatgcgtc gccaatagtt
    16021 cgattgttgt acctggtcct aagaaaatcg tttctccctc gtgaatcaag gaggctgctg
    16081 tggcagcaat ttcttttttt tcttgaatct gcagagtggc tttttcagtg tgagaaagtt
    16141 cttgatctaa agtgtaggaa agactttgag cccctccatg gacacgcagc agcttgcccg
    16201 atttttctaa ttcatctaaa tctctgcgaa cggtcatatc agaaacatct aattgattga
    16261 tgatttcatt aacggtaagg attccttttt tattgaccat ttctacgata gtaagcaatc
    16321 tttctttttt caacattgtc ttcacctcta atttaaggat aatctatcat ataaacggac
    16381 aacagtcaat ctaattcgaa caaaagtaaa catttagggt ggtttttatg tttgttacaa
    16441 tagattttat tgctgttttc tggtttttat gattatttgt gtttgttttt gttgacaaat
    16501 gttttggatg cgtttacaat gcaatcagtt agaaagagcg aaaactgatt atagatttga
    16561 ggagagatgt acatgcttaa attaccagaa gattttattt ttggcggagc cacagcagcc
    16621 tatcaggttg aaggagccac taaggaaggt ggcaaaggcg ctgttgcttg ggatgacttt
    16681 ttagaggaac aagggcgatt cagtcccgat ccggcaagtg atttttatca tcaatatgca
    16741 aaggacattg aattgtgtga acgttttggt gtaaatggtc taagattatc cattgcttgg
    16801 agccgcattt ttcctgatgg agctgggaaa ccaaatccag aaggaatcgc tttttatcat
    16861 cgtgtgttcg aagaatgtaa gaaaagaaac gtaacgccgt ttgtgacgtt gcatcatttt
    16921 gataccccta aacgtttgtt tgaccatgga gattttttga atcgagaaac aatagaagca
    16981 tttgtttcct atgccatttt ttgttttcat gaattcaaag aagtcaaggt gtggagtacc
    17041 tttaatgaaa tctatccagt tgcaaccaat caatatttgt taggtgtttt cccaccagga
    17101 atcaaatatg attttacaaa gatcgtcgcc tgtcttcata atatgatggt tgctcatgcc
    17161 cgtgtagtga actatttcaa agaaaacgaa cttccgggtg aaattggtgt agttcactca
    17221 ttagagacga aatatgcggc aacagacgcg ccggaagata agcatgctgc ctttttagac
    17281 gatgcattgt cgatccgttt cttattagat gctacctatt taggctatta ttcaactgaa
    17341 accttgactg ctcttgatga gatatgtgaa gcaaatcagg ccagctatca ttttcctgaa
    17401 gaagatttcg ttgaattgaa aaaagcatcc acgcgtaatg actacttagg gatcaatcac
    17461 taccaatgcc attttgtcaa agcttacgat ggagaaaatg caatccatca taacggtacg
    17521 ggtgaaaaag ggacctctgt ttataaagtg aagggaatcg gagaacgtat ttataaagaa
    17581 ggaattcctc gaactgattg ggactggctg atttatccag aaggtctata tgacttgttg
    17641 ctgcgaatta aaagcgatta cccacattac aacaaaatct atatcactga gaacgggatg
    17701 gggtataaag atcagtttga agatggcatt attatggatc agccgagaat cgactatttg
    17761 agagtctatt tggaatcctt aagcaaggcg ataacagccg gggtaaatgt gaaggggtat
    17821 tttttgtggt cgcttatgga tcttttctca tggacaaatg ggtataacaa aaggtatggc
    17881 ttgttttatg ttgattttga aacccagaag cgttacccaa aagaatcagc ttactggtac
    17941 aagttggtca gtgaaaccaa aacgattatt taataagtga taatggagga agaaaagatg
    18001 aataaagagg aattacaaat gcttggtttt gagatcgttg catattcagg cgacgctcgc
    18061 agtacattat tgaaattatt gaaagaagta agacaaggaa actttgaaca tgttgattcg
    18121 gcgttgaaag aagccgacga aaatttaacc cttgcacata attcgcaaac aaaaatttta
    18181 gcggaagaag catctgggaa agagatggag atgggattca tttttatcca tgggcaggat
    18241 catttaatga ccactttatt gctgagagat ctgattcaag actttattgt actgtacaga
    18301 cagaatcaag gataggagaa gaacgctatg gatggaatca ttaaacaaat cgaaaaaggg
    18361 aaaccatttt ttgaaaaaat ctcacgtaat agttatttag gagccgttcg tgacggattt
    18421 ttaacagcga tgccagctat tttattttca agcattttca ttttgattgc tgcggttcct
    18481 gagatttttg gttaccaatg gcctgaatct gtctccacat ggctatggaa agtctataat
    18541 tattcgatgg gtgttgtagg gttactcgtt tcagcaacca ctgctcgctg cttggctgat
    18601 tcgatgaatc gtcgcttacc gaaaaacaaa gtaatcaaca ccacctctgt gatgctggcc
    18661 tctgtggtaa gtttcctgtt gttaagcgtc tctccgattg aaggtggatt ttcaacggaa
    18721 tatatgggga caaagggact actggcttcc tttgtcgctg catttttaac agttaattta
    18781 tataagtttt gtgtgctgaa agatattacc attaaaatgc ctaaagaagt tcctggaacg
    18841 atttcgcaaa ccttccgaga tatttttcct ttctcttttt cagtatttgc ggccgtttta
    18901 attgatttag gcattcgaca aatcttccaa atctcatttg cagaagcaat cattacggtg
    18961 ctgcagccgc tatttacagc agctgacggg tacttaggaa tcgctattat ctggggagcg
    19021 atggcgctgt tttggtttgt cggtgttcat ggaccgtcga tcgtggagcc ggcaattgcg
    19081 gcaattatct atgccaatgt ggaaaccaat ctgcaattgt tcaattccgg tgaacaagct
    19141 tctaaagtac tgacggtggg tttagggaat tttgtaggaa ctatgggagg aactggggca
    19201 acattggttg ttccttttat cttcctactc tttgctaagt ctaagcagtt gaaggcagtt
    19261 gggaaagctt cctttattcc agtaagtttc gctgtcaacg aaccattgct atttgcggca
    19321 cccatgattt tgaaccctta tttttttatt ccatttttgt taacacctgt tgtaaacgtt
    19381 tgcctgttca agttttttgt cgatgtattg ggcatgaaca gctttatgta cgttttgcct
    19441 tgggcaactc cagcaccgat cggtttggtt ctaggaacgg gcatgggtat cttagctttt
    19501 gttctagcag cggttctaat cgtcgttgac ttcctgatct atctaccatt ttgcaaagca
    19561 tacgatgctg tcttagtaga gaaagaagca caaaaagcag aggtgatcgc aaccgaggaa
    19621 ggtgcttctg ccgatgtacg tgaggaagta cctgtggcag cgagtcaagt tatcagcgat
    19681 gcaaataaag aaatcaatgt gttggtactt tgtgctggcg cagggacaag tgggatgtta
    19741 gctaatgctt taaaaaaagg tgcatctgaa tcgaaagcac cgatcagtgc aatggcgggt
    19801 gcttatggtt ctcattacga aatgctgcag gattttgata tggtggtctt agcaccgcaa
    19861 gtcaattctt actatgatga tatcaaagaa gacaccgatc gcttaggaat caagctggtt
    19921 gcgacaaaag gagcagaata tatcggatta acgagagatc ctgaaaaagc tgttcagttt
    19981 attctgaacc aatttcaata aaggaggagc cataatgaaa atgggaattt ggttgcgtaa
    20041 agctgtttta tttgcagctg tgttaggggc tttgggggct gtttcaaaaa ctgttgaagc
    20101 atctgccagc gaatttattc gcggagcaga tatttcgatc ctgtcagata tggaaaaatc
    20161 tggtgcaaaa tattatgaag acgatatttc aaaagatgcc ttagagattt taaaaaataa
    20221 tggtgtcaac tatgttcgac tgcgtttgtg gcaggatcct tataatagta atggagaaag
    20281 ttatggagca gggacaaatg atctggaaac gacgattgac cttgcaaaac gagcaaaaaa
    20341 tctgggactt aaggtgctgc tggattttca ctacagtgat ttttgggttg atcctgggaa
    20401 acagaatctt cctaaagcat ggcaaggtct gacctttgaa gaaatgaata cggcattgta
    20461 cgactataca aagaacgttc tgtcggaaat gaagcagctg gacgtttatc ctgatatggt
    20521 tcagatcggc aatgaactga atagcggaat gctctggcct tatggcaagt cttggggaga
    20581 aggcggggga gaatttgatc gattggctgc ttttttgaag tctggtatcc aagctgttcg
    20641 agacactcaa cctaaaacaa ctccagtaat gctccactta gctgatggtg gcgatacagg
    20701 agcatttact tggtggtttg atgaaatcac gagtcgaggt gtgtcatttg atttaattgg
    20761 agtgtcgtat tatccgtatt ggcacggttc aatgaatgaa cttcaaacca atatgaatgc
    20821 gatcagccaa cggtatggta aagaagtgat cgtagttgaa acagcttatg ggcatacaac
    20881 agcgaatgcc gatactatgc caaatgcttt tggtgaagcc gaagcagctg cggggggata
    20941 tgaaccaaca ccgacaggac aagcagagta tttgctggat cttgccgatc ggattcaggc
    21001 agtaccgaat aatcgcgggg cgggcttctt ctattgggaa cctctttggt acaacggaaa
    21061 tgtgagttgg gcaacacaag caggtatgaa ttatctcagt gttcaatcca ctatgggaaa
    21121 cgaatgggac aaccaagcga tgtttgattt tgctggaaac gccttgccaa gcttgcgtgc
    21181 gtttaaacaa gcaggggcgc aaataaatct agttaaaaat gcaagtttcg aaagcgatgg
    21241 accaacgacc agtccttcca attggcaaac ctggtttcaa caaggaaccg ctaagggtac
    21301 gatcaaaacg gaagcgggca ctttttttgg ggactacaaa ctaacttttt ggcaggatca
    21361 agcatacgag gcatcagctt atcaaaatgt tagtggcata agcaaaggaa cttacacatt
    21421 gagtgcctat gtaatgtctg ggggagagtt tgatactaat cagttatata tcaaaaatta
    21481 tggtggagcg gaactaaata ctgcggttgt taaaacaagt gaatggacaa aaattacaat
    21541 caaagacatt ccaattacaa caggtgtttg tgaaattggg gtttatagca aggcttcagg
    21601 aaatgcttgg acgaacgttg attttgtttc attggtgaaa caatagactg cggatcgttt
    21661 cgattcaaga tcggaggttc ccttcagcca catcgttagc gtagaaggca ggaatcgaac
    21721 ctgcacctcg cctttgccaa aaataaccag aaacgatttc cagtcatttt taccaaaacg
    21781 agtaaagcac cagacttcat ctacactttg tattatgcta aagagagttc aacgatttcg
    21841 taagaagcaa tgaaaaaatt gcaaaaagtt gtgcagataa cataaagttt gtttaagaaa
    21901 gggtaacctt agaattccgt cgtgaatatg atttgagcac ttagatggat agaaaaaagt
    21961 tctcggaaaa cagttcgttt ttcgagaact tctttttatg ataagaatga aacaaattaa
    22021 cttatattat agtctctttt ggtagggaac catcttattt ttaatgaaaa tcaagcattt
    22081 tagctattga agaatgttga tttataggga ttccccctcc atattatgtt ggctctttat
    22141 tcccactcca ctgttgctgg tggtttagaa gtgatgtcat acacgatacg gttgacgtgg
    22201 gctacttcgt ttacgatacg tacagagatt ttttgcaaga cttcccatgg gatacgggca
    22261 aagtcagcgg tcattccgtc gattgaagtt acagcacgga taccgactgt gtagtcgtaa
    22321 gtacgtccgt cacccataac accgacagag cggatccctg gaagaacagt gaaatattgc
    22381 cagatatcac ggtcaagtcc agcagctgcg atttcttcac gcaagatagc atcagattcg
    22441 cgtacgattt ctagcttgtc ttcagtgatt tcgccaagaa cacgaatacc aagaccagga
    22501 ccagggaatg gctgacgcca aacgattgaa tcaggcatgc ctaactgagt ccctaattca
    22561 cggacttcgt ctttgaataa tgtgtttaat ggttcgatca attcaaattg catatcttct
    22621 ggcagtccac ctacattatg gtgagatttg atcgtctgtg ctgtttctgt accagattcg
    22681 ataacgtcag tatacaacgt tccttgtgct aggaaagaga cgccttcttc accagcaagt
    22741 tttgttgctt cgtcatcaaa aacatatacg aattcattcc caatgatttt acgtttttgt
    22801 tctgggtcag atacaccttt caacttgtct aagaagcgat ctcttgcatt gactttgatg
    22861 atgttcaagc cgaattttcc gcctagactt tccattactt gttccgcttc gcctttgcgt
    22921 agcagaccgt ggtcaacaaa gatagatgtc aattggtcac cgatcgcttt ttgtaaaaga
    22981 accccaacga cactagaatc aacgccacct gaaagaccaa gcaagacttt tttgtcacca
    23041 acttgttcac ggattttttc tacttgcata tcgataaagt tatccattgt ccagttacct
    23101 tcacagtgac aaacatcaaa ggcaaagtgg cgcagcaatt cgattccgta ttcggaatga
    23161 cgtacttctg catggaattg gataccataa aaattacgtg ttgtgtcttg gatagaagca
    23221 atcggacaat ctttgcttgt tccgactgtt tcaaagcctt caggaacttt agttaccaag
    23281 tcaccatggc tcatccatac tgtttgttgt tttggtgttt ctttaaacaa gacagcttga
    23341 tcgcttgtta cttctaacaa ggctttccca tattcgcggt ttttagcagg ctctacggaa
    23401 ccgccaagtt tgtacgtgat caattgcata ccatagcaaa tccctaatac aggaatacct
    23461 aaattgaaga tctcaggatc gatcccaaat gcattctcat catatacact gtttggtccg
    23521 ccagaaagaa tgattccctt tggattcatc gcttttactt cttctgcagt aatgcggtgg
    23581 ctcaataatt cggaaaagac tccaagatca cgaatacgtc ttgtgatcaa ttggttatac
    23641 tgactaccgt agtctaatac gataatcttt tcaacgttcg tcatatcggc aacgtttgtc
    23701 aaatttatta cccctatccc tttaaatttt atctcaaaat agtcaaacta ttttaaaatg
    23761 ctaatatttt cgcatgaaaa tcgaatcgat gatatgattt tcagttttat ggagaattat
    23821 atcggctctt cctcgtgtag gcaagatata ttcctgtaaa tttttcaaat tcacattttt
    23881 ccatacatct tttgccattt taaaggcttc ttcacgatct ccgatagcaa aacgataata
    23941 ataattctct ggattttgga aagccgtatc cagtaacgca ccaaaacgat ccaaatacca
    24001 tttttcgatc agcacgggat cggcatcgac atagacagaa aaatcaaaaa agtcgctgac
    24061 gtagatttgc tgattcgcag gtaattgaag cgtattgatc ccctcaacga tcaagatatc
    24121 aggctgctgg atcaattcgt acttgtctgg aatgatatca tacacatcat gtgagtaaac
    24181 aggtactttt atctcttcct gaccagattt tacacggttc aagaaatcga tcagcatctc
    24241 catatcataa ctttcaggaa atcctttacg gtccatgatt ccacgctctt ttaatatacg
    24301 atttggataa agaaatccgt cagtcgtgat cagctgaacg tttcttcgtt tgaaggtacg
    24361 agacaaaatc gtctgcagca gtctggctgt tgtacttttt ccaacggcta cacttccggc
    24421 gatcccgata ataaaaggcg gtacttctac gtatttatga agaaataaac ctttactcaa
    24481 gaacaaagat tcaaattctt tcatataaag ataaatcaga tgagcaagag gtacatagat
    24541 atctcgaaca tcctgcatgg aaatgcggtc attcaaactt ttgatattat ctagttcatc
    24601 ttgtgtcaaa ggtgcttgcc cattacgata aaattctcgc cattcttctc ttgccacacg
    24661 gtagtagttc attggatcat tcatattagc ctcctgcgtt ctcccatcaa tggaactatt
    24721 ttaacacaaa ataaacgcaa accccaccac ttaagagaga ttgccgatct ttttgtataa
    24781 tctttataat agaaagaaac ggagtcttat tcttgacttg cgcacggata cataaaagga
    24841 tagactgttg tcatgaaaga aatgagaagg atggaagaca tgacaaatca ttactattct
    24901 gaacgcccag atacggcgca cgattttgaa caatgggctt ttgagttaaa aggcagaacc
    24961 tttcaatttg taacagattc tggtgtattt tcacgtgaaa cagtggatta tggttcacgt
    25021 gtcctgattg atgctttcga ttgggaagag ttacctgatg aaggaaagat cttagatgtg
    25081 ggatgcgggt atggaccgat tgggttagct ttggcatttg cgacacagcg gtttgttgaa
    25141 atggtcgaca ttaatgaacg agcggtaagt ctagcgcaag gaaacgcaaa gcgtaaccaa
    25201 atcgaacatg ttgatatcca tcaatcgaat atctatgaag cagttcatga agaaacctat
    25261 gcagctatcg taagcaatcc gccgatccgt gctggaaaaa aagttgtaca tgaaattttg
    25321 acaggcgcat atcctcggtt gaagaagggc ggtacactga caattgtgat ccagaagaaa
    25381 caaggagcgc cgagtgcgca aaagaaaatg gaagaaacat ttggtaatgc agaaatcgtc
    25441 acaaaagata aaggatatta tatcatcaaa agtgtgaaag aataactagc tgaaaaatag
    25501 tggagcgacg aaagagtgga actgggcgtg catgtacggg tacgtatcag ttcttttttt
    25561 gttgagaagt ttttaaaaac aaagaactat tttttcttca aaaagaaata gtaggaacag
    25621 agtcgttgtt ttttacgata aaataaataa gatacagaac ttgtatagaa ggctgccaag
    25681 tcggtagata aaggaggttt ttatcaaaaa acatactttc cttttttctc tattcttttc
    25741 ttgggggttt tggtacactg atagggaatt tagatagaag ggagccaata ggatgaagct
    25801 gaccatcaga gatatcgcag aaatggcagg cgtatcagta acaactgtct cacagatttt
    25861 gaataacaaa ggaagcagat ttagtgataa gacaagaaaa aaagtgttgt cgatcgtgaa
    25921 tgaacatcat tataagcccg attatttcgc ttcaaatgtg atcaatcgac attcaaagac
    25981 catcggaatg atcgtccctg atgtcactga tttcttcttc tccaaactga tcgaaggtgt
    26041 agagagctat ttgaatcctt tgggctatgt gatcatgtta tgcaattctc gtcatagcca
    26101 agaaaatgag atcaagtatt tacaagagct ttcccaccgc tcagtggacg gaatcttgct
    26161 ggccacacca aatattttac ctgagaaata tgcattagac agcggttttt atcaaaaaat
    26221 gccaatcatt ttaatcgatc gcggattgaa tcgtcgggat aacggacggc ttatcgtaaa
    26281 ggaatatgag ggcgcctatc aagctgtttc gctgtttatt gaaaatggcc atacgaagat
    26341 cggcatgctg aaggaaacca ctggatacta tcaattagaa gaacgtttca acggatatcg
    26401 tcatgcgctg aaagatcatg gcctgccttt taatgggaaa tttgttgaac atggagagtt
    26461 gactgtccaa ggtggatata ctgcatcaaa aaaattactc aaacataaag atatcacggc
    26521 tattttttgc gggaatgatg ccatggcgat cggatgctat caggcgatcg atgaattggg
    26581 caaaaaaatc ccagaagata tctcagtcat aggattcgat ggattaaagc tgtcagaata
    26641 catgattccg caattgacga cagtgcagca gccaagtttt gatattggat tttatgctgc
    26701 acgtttcctg atcgatacga tcgaatttcc tcaaagaaaa gttccgaaca aagtgttcga
    26761 aacaaaatta attattcgtg agagcgtaaa agtattgaca aagggctaac tcggcggtat
    26821 attgcttatg taagcattta caaaggctag ttagtgcttt ttttattttt agtaaaccag
    26881 tttactaaag tggtttacct ttcctaaaaa taatgtataa taccgaatga agacaaggag
    26941 gatcaggcaa tgcgaatggt ggatctgatt gaaaaaaaga gggatggaaa cgagctgtcg
    27001 aaagaggaaa tcgagtacat cgtcacgaac tatacgaatg gaaagattcc agattatcaa
    27061 gtcagtgcat tattgatggc aattttttat caagacatga caaatgaaga aatcacgaac
    27121 ttaacattgg cgattgctaa ttctggtgat gtcatcgatt tgagttctct tgaaggaata
    27181 aaggtagata agcattcgac aggtggcgtt ggtgacacga ccacattgat tttagccccc
    27241 ctagtagcta gtgtcggagt gacagtggct aaaatgtctg gacgcggtct aggttacaca
    27301 ggtggtacac tagacaagct agaagcaatt cccggatttc agatcgagct ttcggatgaa
    27361 gaatttgtac gcattgttaa tgaaagtaaa gtagcggtaa ttggtcaatc aggaaacttg
    27421 gcaccggcgg acaaaaaatt gtatgccttg cgtgacgtca cagcgaccgt tgattctctt
    27481 ccgctgattg ccagttcgat tatgagtaaa aaaatcgcgg caggagcaga tgcaatcgtt
    27541 ttggatgtga ccactggaga cggtgctttc atgaagaaca tcgaagatgc aagacgtctg
    27601 gcaaagacca tgacgagcat tgggaaactg gctaaccgag aaacagtggc ggttatctca
    27661 gatatgtcag aacctcttgg cgaagctatc ggaaatagtc tagaagttgt cgaggcaatc
    27721 gaaacattac aaggaaatgg tccagaagat ctagtagaaa tgtgctacgc cttaggaagc
    27781 caaatggttg ttcttgctgg caaagctaag acaaccgatg aagcaagaac gttgcttcaa
    27841 gaagctctgg aatcaggtaa agcgttagca aaattcaaag aaatgatcca aaatcaaggg
    27901 ggagacccag cgatcgtgga acatccagaa cgaattttga ctgcacgcta cacaatggag
    27961 cttcctgcta aacaaagcgg agttgtgtca aaaatcgtgg caaatgaatt aggaattgct
    28021 gcaatgatgc taggtgctgg gcgtaaaacc aaagaagaag atattgatca cgctgttgga
    28081 ttgaaactgc ataaaaaaat tggtgacact gtgacaaaag gtgagtcact attgacgatc
    28141 tatagtaacg acgaagaaat cacttctgtc attgaattat tatataaaaa tattgaaatt
    28201 ggtgaatcgg caatgaagcc aacgttgatt catgacatca tcacagaata aaggaaaaaa
    28261 gcggacttta ccgttttaaa gaaaagggga aaagaaatgg aactaaaccg aatgatcgac
    28321 catactattt tgaaagcaga cgcatctaaa gaagctgtga tgcaaattat cgaagaagca
    28381 aaaaaatacc atttttattc tgtctgcatc aatccagcat gggttgcgct agcgaaagaa
    28441 caattacaag gtgagccagt agccgtatgt acagtaatcg ggtttcctct aggagcaaac
    28501 acacccgaga caaaagcatt tgaaacaaca gatgccatca ataacggtgc agatgaagtc
    28561 gatatggtca tcaatatcgg tgctttgaaa tcaaaggatg atcaacaagt ccaaaaagat
    28621 atcgaagcag ttgttgaagc agcaaaagat cgtgcgcttg tcaaagttat tattgaaaca
    28681 tcgttattag atagagaaga aatcatccga gcttgcgaaa tagcaaaagc tgcaggcgct
    28741 gattttgtca aaacatcaac tggtttctca acaggcggag caaaggtaga ggatgtccgt
    28801 ttgatgcgtg aaactgtagg accagaaatg ggtgtcaaag cttccggcgg tatccataac
    28861 gaagaagaag caatggcaat gatcgaagct ggtgctacaa gaatcggaac aagcgcagga
    28921 gtagcaatcg tatctggttc aactggtgaa ggctattaat tttttcaaag gagaagctca
    28981 tggcagaact caaacaagaa tggatcaaca cagctattga agcgttagat aaagcctatg
    29041 ttccttattc ccattttccg gtaggcgctt gtctcgtaac ggaatcaggc aagatttatc
    29101 aaggcatcaa cattgagaat gcatcatttg gattaacgaa ttgtgccgag cgcacagctt
    29161 ttttcaaagc agtatctgaa ggagaaaaaa catttacgca tctagtcgta gcggggcaca
    29221 cccccgatcc tatctctcct tgtggtgcat gtcgacaagt aatggcagaa ttctgttccc
    29281 ctgatatgcc ggttacgcta gtaggagaca atggtgtgac gaaggcaacg accgttcgtg
    29341 cactgctgcc ttatgcattt actgaaaaag atctataact catgttcatt cagtcagctg
    29401 actgttgaaa aataaaacaa ttattttagg aggctttaca gaaatgaaaa aagcaaaatt
    29461 atttggttta ggtgctgtcg cactagcagc agggttattt ttaggtgcat gcggcaacaa
    29521 cggctctact gattcatccg gtggcaaaag ctcatcagac acaacaactg cagcattgat
    29581 cacagacaca ggtggtgtag acgaccgttc attcaaccag tcagcttggg aaggactaga
    29641 aaaatggggg aaagatcaag gactttcacg aggaaatgat ggcttccaat atttccaatc
    29701 ttcaaatgaa tcagattaca tcccaaatat tgaccaagca ttgaatgctg gattcaaaac
    29761 gatttttggt attggttata aactaaaacc agcgatccaa gaacaagcaa caaacaatac
    29821 aggtacgaac tttgttatta tcgatgatgt catcgatgga ttagataacg ttgtatctgc
    29881 aactttcaaa gacaacgaag cttcttatct tgcaggtgtt gcagcagctt atacgactga
    29941 aacaaacgta gtcggcttta tcggcggtgt aaaaggtgaa gtaatcgatc gttttgatgc
    30001 tggattcaaa gccggtgttg atgcaggtgc gaaagaatta ggaaaagaaa tcaaagtatt
    30061 gaatcaatat gctggtgact tctctgctcc agataaagga cgttcaattg ctcaaggtat
    30121 gtatgcacaa aacgcagata tcatcttcca tgcttcaggc ggtacaggta acggtgtatt
    30181 ccaagaagca aaatcattga acgaatcagg cgacaaaaaa gtttgggtta tcggtgttga
    30241 ccgcgaccaa tcagacgaag gcgaatacac attaaacggc gaaaagaaaa acttcacatt
    30301 gacatctaca ctgaaagcag ttggaacagt agtagaagat ttggcacaaa aatcagcgga
    30361 cggtaaattc cctggcggcg aacacactgt ttatggattg aaagaagacg gtgttggtct
    30421 aacagaagga caactttctg acgaagcgaa aaaagcagtt gatgaagcaa aagaaaaaat
    30481 catttcaggt gacgtaaaag ttccagaaac tcctgaagaa aactaaaacc atttctatag
    30541 ccttgttaga cacatgtttg acaaggctat ggtttgatta gaacaagaat tgttcattta
    30601 tccaagctgc cttgtgacag tttggataag ggaacaactc cctgaagtaa tgtttgtttc
    30661 aaaagaagaa cgctcactaa gcgtgaatct tagtcaatcg ttgccctaga tagaaatcgt
    30721 taggatgtga aaaaaaggtg gttcaagaaa atattgtcat agaaatgcag aatattacca
    30781 aagaatttgg aacattcaag gcaaatgaca acatcaattt acaagtaaag gcaggagaaa
    30841 ttcatgcgtt gcttggagaa aacggtgctg gcaaatctac attgatgaac gtgctttccg
    30901 gattattaga gccgacatca gggaaaattt tgatgcgtgg gaaagaagta aagatcacaa
    30961 gtccgaccaa agccaaccaa ttagggattg ggatggtcca tcagcacttt atgcttgttg
    31021 atgcctttac tgtaacagaa aacatcgtgt tgggaagcga gcctagtcgc gcagggatgc
    31081 ttgaccataa aaaagcacga aaagagatcc aaaaagtttc tgaacagtat ggattgtcag
    31141 tcaacccaga tgcttacgtt cgtgatattt cagttggaat ggaacaacgg gtagaaattt
    31201 taaaaacact ttaccgagga gcagatgtac tgatttttga tgagccgaca gctgtattga
    31261 cccctcaaga aattgatgaa ttaatcgtga tcatgaagga attagtcaaa gaaggcaagt
    31321 cgatcatttt gattacgcat aagttagatg aaatcaaagc agtagctgac cgctgtacag
    31381 ttatccgccg tggaaaagga atcggtacag tcaacgttaa agacgtaacc tcacaacaat
    31441 tagccgatat gatggttgga agaacggttt cattcaaaac gatgaaaaaa gaagcgaagc
    31501 ctcaagaagt cgttttgtct attgaaaatc tagtggtgaa agaaaatcgt ggattagaag
    31561 ccgtgaaaaa cttgaactta gaggttcgtg ctggcgaagt acttggtatc gctggaatcg
    31621 atggaaacgg gcagtcggag ttgatccaag ctttgactgg tttgcgaaag gcagaaagcg
    31681 gacatatcaa gctaaaaggg gaagacatca ctaataaaaa accccgaaaa atcactgaac
    31741 atggtgtagg acacgtgcca gaagaccgtc ataaatacgg gttagtccta gatatgacat
    31801 tatctgaaaa tatcgcacta caaacctatc atcaaaaacc ttacagtaaa aacggcatgc
    31861 tgaattattc agtaatgaat gaacatgcca gagaattgat cgaagaatat gatgttcgaa
    31921 caacgaatga acttgttccc gcaaaagctt tatcaggcgg aaatcagcaa aaagcaatta
    31981 tcgctcgtga agtcgaccga gatcctgatc tgttgattgt tgcaaatcca actcgtggac
    32041 tggatgtagg tgcgatcgaa tttattcata aacgtctgat cgaacaaagg gacaaataca
    32101 aagcagtgtt actgatcagt ttcgaattag aagaaatttt aaatgtttcg gatcgtattg
    32161 ctgttatcca tgaaggagaa attgtcggta tcgttgatcc gaaagaaaca tctgaaaatg
    32221 aattaggtct attgatggcg ggctatacct tagaagaagc acgaaaagag ttagaaaagg
    32281 gggctggcgc acatgaatga tcgcagcgaa aaattccgta atttattagt gcctgtactt
    32341 tcagttgttt taggattgat cttaggcgcg atattgatgg ctgcttttgg ttttcagccc
    32401 atccaaggtt attcttctat gctagatgca gcccttggtt cgcaaagagg gataggtgaa
    32461 acgttaaggc aagcaacgcc gttgattttt acagcattag gtttttctgt agctaactca
    32521 gctgggtttt tcaatattgg gctttctgga caagcacttt gcgggtggat cgtcagtgtc
    32581 tgggtggcac ttgcgtttcc agatctgcca aaagttgttt tgcttccgtt atgcgtgatc
    32641 ttaggtgcct tagctggtgc gatggcagcg gctgttccag gtttacttcg agcatttttt
    32701 ggaacaagtg aagtgatcgt aacaatcatg atgaactata tcttattata cgtaagcaca
    32761 tttgctttac atgaagtgat gcctgaaagc tatcgctcaa gtttggactc ttccaatatg
    32821 atcagtcaaa atgcctcact gcggttacca tggttaacac aagcttttgg cggctctcgc
    32881 gtaaactcag gattattttt agcaatcatc gcgcttattt tcgtttggct gctgatgaag
    32941 aaaacgactt taggatttga aatccgttct gttggattga atccttttgc ttctgagtat
    33001 gcaggaatga gtagtaaacg tacgatcgtt ttgtcgatgg tcatttctgg cgctttggca
    33061 gggcttggcg gtgtggttga aggattagga acgtatcaaa acttctttgt tcaaacgact
    33121 tcgctatcta ttggatttga cggaatggct gtttccttgc ttggttctgg atcagcaatc
    33181 ggtattcttt tatcagcgat cttgttcagt attttgaaga tcggtggact tggcatgcag
    33241 acaggagcag gtgttccgtt tgagatcgtc aatgtatcga ttgctttgat tatcttcttt
    33301 gtcgggatca acttcctgat tcgtttcgtc atggctaaag tcttccaagg gaaaaaacaa
    33361 gaagagatcg ttgcgacaat agaatcgaaa ccaacgaatc aaaaccatga agggggcgaa
    33421 ctataatgtc gactatcgaa ttaattgcct tgatccttac ttctacactg gtttattcaa
    33481 caccgctaat tctaacgtca ctaggcggaa ctttttctga acgaagcggg atcgtaaacg
    33541 tagggctaga gggaatcatg gtcatgggtg cttttagttc catcgttttc aacttgacga
    33601 tgagtccatc acttggttct atgacaccat ggatcgctat tttagtgggt ggcgtcgtag
    33661 gtatcctatt ttctctgatt cacgcagtag caacagtcag tttgcgtgct gaccatatta
    33721 tcagcgggac agtaattaat ctgatggcac ctgctttagg tgttttcttg atcaaagcat
    33781 ggtatggtaa aggtcaaact gataacatca cgcagaatct ggggtatttt tctttcccag
    33841 gattagcaga tattccggtc attggaccaa ttttctttaa aaatacattc ttacctgctt
    33901 attgtgctat tttgattgct gtcctagctt gggtgatcat cttcaagacg aaattcggct
    33961 tgcgcctccg ttcagttggt gaaaatcctc aagctgccga cacattaggt atcaatgtat
    34021 atgctatgcg ttattcaggc gtactgattt ctggcttgtt aggcggtatg ggcggtgctg
    34081 tttttgctca gtcgatttcc ggtaactttt cagctggtac gatcgttgga caagggttca
    34141 tctccatggc tgctatgatc tttggtaagt ggaatccttt aggggcaatg ggtgcctcat
    34201 tgttctttgg ttttgctcaa agcttgagta tcattggcgc acaattacca gttatttctt
    34261 cgattccgcc agtattgctg caaattgctc catatttgct gacaatcatt gtgctggttg
    34321 ttttcttagg gaaagcttct ggtccaaaag caaacgggaa gaactatatc aaatcaaaat
    34381 aatcttttag cgaataaaaa gggtgggtta cgggaagtgt ttttcgtctc gccctttttg
    34441 ttttaaaggc aataaaaata aaaagaaaga aggaataatc atgtttaaac gcgtacatct
    34501 gatcgtcatg gattcagtag gaattggaga agcaccagat gccgataagt tcggtgatgt
    34561 tggttctgat acattaggac acattgcgaa agaagcagga ttgaacgttc cacatttaga
    34621 gcagcttggt ttaggaacga tccgtcctct tgaaggtgtg gaatcagtga aagatcatca
    34681 aggctatgcg acgaaattag aagaagtttc tgtagggaaa gatacgatga caggccactg
    34741 ggaaatcatg ggattgaata tcaaaactcc atttcgtgtg tttcctaatg gattccctga
    34801 tgatctgatc aaacaaatcg aagaattttc tggccgtaaa gtcgtatgta acaaacctta
    34861 tagcggaaca gctgttattg acgattacgg tgaacaccaa atgaaaacag gcgatttaat
    34921 tgtatatact tctgccgatc ctgtccttca gatcgcggca catgaagaaa tcattccttt
    34981 agaagaatta tatcggattt gccaattcgt tcgtgatata acaaaagatg atccgtatat
    35041 gattggccga atcattgcac gtccgtacgt gggtgaacca ggagacttca cacgaacaag
    35101 caatcgccat gattatgcgt tgaatccatt cggacacaca gtccttgatt ctttgaaaga
    35161 agcaggaaag gacgtgattg ctgttggaaa gatcaacgat attttcaacg gacaaggaat
    35221 cactgaatct gtccgcacga aaagcaatat ggatggcgtt gaccagctgc tgaaagttat
    35281 gaaaaacgat ttttcaggaa tcagctttac caatttagta gattttgatg cattatacgg
    35341 tcatcgtcgg gatgtagtcg gctatgcgca tgcgattgaa gaatttgact tacgaattcc
    35401 agaattgctt gaagcgatgg aagaagacga cttgctaatg attacagccg atcacggaaa
    35461 cgatccgacg tttactggta ccgatcatac gcgagaatat gtaccgttat tggtttacag
    35521 taaaaaaatg aaagaacaag gggcattgcc tcaaggatat tattcagata tttcagcaac
    35581 gattgctgag aactttagtg tttcttcgac tgaaaatggc gaaagcttct tgaaattatt
    35641 aaaataatct ttttaaatag gagaaagcaa atgaccaagt taagcgagat gttacaagaa
    35701 acgacccagt ttatccttga taaaggagta aaagaaattg attttggttt gattctaggt
    35761 tcaggattag gtgaattagc agatgaaatc gaagatgctg taatgatttc ttatgatgag
    35821 atcccgttct ttcctgtttc gacagtagtt gggcatgcag gaaagctagt ttatgggtct
    35881 ctggcaggca agaaagtgtt agccatgcaa gggagattcc actactatga aggtcattcc
    35941 atgcaaacag tgacctatcc agtacgtgtg atggccggac taggggccca ttcagtcatt
    36001 gtgactaatg catgtggtgg tgtcaacgaa tcatttgtac caggagattt gatgctgatt
    36061 accgatcata tcaattttac tggtgaaaat cctttgatcg gtccgaatga agatgcaatg
    36121 ggccctagat ttccagatat gagtcaagct tatacgcctg actatcaagc aacagcaaaa
    36181 gcagcagcag aaaaactagg tttggatctt aaagaaggcg tatatatggg ctattctgga
    36241 ccaacttatg aaacgcctgc ggagatccga atgtctcgga caataggagc cgatgcagta
    36301 gggatgtcga ctgttccaga agtcatcgta gcagctcaca gcggattaaa agtgttagga
    36361 atctcttgta ttaccaactt agcagcaggt atgcaagcga atctgagcca tgaagaagtt
    36421 gtagaaacaa ctcagagagt caaacaatct tttaaagcat tggttaaaga aacattgaca
    36481 ttattgtaat aggaggaaca ataaaatgag tgtgcatatt gaagcgaaag aaggcgagat
    36541 cgccgataag attttacttc cgggagatcc tttgcgagct aaatatattg cggagacttt
    36601 tttggaagat ccagtttgtt acaatcaggt acgcggtatg ttaggcttta ccggcaaata
    36661 taaaggagaa cgtatttctg ttcaaggaac aggaatggga atgccatcag ccaccatcta
    36721 tgcccatgaa ttgatccagt cgtatggtgt aaagaaattg attcgagtag gtacatgcgg
    36781 tgcattgtca aaagacgtcc atgttcgtga tttagtacta gcacaaggtg cagcgaccag
    36841 ttcttcgatg atcgaaaaaa atttccaagc ctttcatttt cctccaatca gtgatttcaa
    36901 tctattactg aaagcatatg agatagctaa agaaaagggc tatacggttc atgtaggaaa
    36961 tgttctttcg gaagattctt tctacaaaga tgatttgaca gagacgttcc aattagctga
    37021 acttggcgtt ttaggagtgg aaatggaagc agcggctctt tattacttag gcgcgaaata
    37081 ccatgtgcag acattaagtt tgatgaccgt tagcgaccat ttgatcaccg gtgaagaaac
    37141 aacagctgca gaacgtcaat ctacgttcaa tgaaatgatc gaagtaggat tggaaacagc
    37201 gatagcagaa taagaaggaa atgaaaaagc tgccctgcat taagtaataa gaacatccaa
    37261 gcaaaaatag ctcctcatgt ttttgacttg gctggactta ttattgcaaa tgtaagcttt
    37321 tgaacaccgt ttaccaagag gttgtgaatc tgccgtttaa ctctgagtca caaggaacaa
    37381 tttcaaaaaa cagcttttca tgtttgatga atattgtgac ttgtgaccga gaagttggca
    37441 ggagaaaacc gtttatacga aaaaagggac tgtgacaaat cgtgtcacag tccctttttt
    37501 atagtgtttt ttataggtag tattttttag caactgttaa gtcatcattt aattcataaa
    37561 caagtggttg acctgttgga atttcaagat ccatgatgtc ttcgtcagag ataccttcga
    37621 tatgtttagc tagggcgcgt aatgagttac catgtgcagc tactaaaaca gttttgttgt
    37681 ctagtaatgc tggagcaatt tcatcttgcc agaatggcaa agcgcgttct aatgtcactt
    37741 tcaagttttc tccaccagga atatcgcgtt tgtctaacat tgcgtaacga cggtcatttg
    37801 ctgcagaacc ttcgtcagtt tcttccatta atggaggaag agtatcgtaa gaacgacgcc
    37861 agatgtgcac ttgttcgtcg ccgtattttt cagctgtttc ttttttgttc aaaccttgta
    37921 atttaccata gtgacgttcg tttaagcgcc atgatttgat ttgtggtacc caaagttgat
    37981 ctgaatattc taagatcaag ttacatgttt tgattgcacg agttaaaaca gaagtgtaag
    38041 caacatcaaa ttcgattcca gcttctttga ttttgcgtcc gccttctttt gcttcttcga
    38101 ttccttctgg tgctagattt acatcagccc aaccagtaaa ttggttcaat gcattccatt
    38161 cactaagacc gtgacgagaa aaaactaatt ttggcatgtt tagctctcct tttaagatag
    38221 gtttatattt ctgaaatttt cagttctgtt ttattgtaca attttttgga agagatttcc
    38281 atcgaaaaat tagataagat tctatgagaa aacaagtaga gaatataaaa aaacgaacag
    38341 tgcccacgca actgttcgtt tttaggtatt agatgcataa ttgctcgatt tctttttcag
    38401 gtaaattgat atatttataa catgttccaa ctgaaacacc gcattttgaa gaaataaatt
    38461 ggatcgtttc ttttttttca taatagagac gtcggatttt tttgatcgtt tttgcatcga
    38521 tttttggtct tccgccgatt tttccttttt tacgagcttc atctaatcca actaatgtac
    38581 gttctttgat caatgcgcac tccatgtttg ctaggttttc cattaattgg aaatagattt
    38641 ttcccatttc gcgcgtatcg attccttcat caagactaat caagtgcagc ccgcgatctt
    38701 tgaataattg cgtgagttct gttaattgcc gcgtagattt gcctaatcga tgaagttggc
    38761 aaatgactag tgcatcgcct tgttgcatgt cagcgatcac tgactccaaa tgaacagcag
    38821 tagaatcatt ttgttccact tcatatgtct catggaaaat ttcttgacaa ccaaagtcag
    38881 ataattgatc aacctgagtt gttaaatcaa cgtcatttat ggttgtgcgt gcataaccaa
    38941 taattttcat ggtgattcct ttctagcagt gattttctaa ctggatataa cagtaaaaat
    39001 gtagcataaa gtacgtcaaa aagatagttt tttcgcaaat tttccgctgt ctttttttat
    39061 tggatgatca agcagttttt ctttatttac gacggattgc gtcaagaatc tcaacgcctt
    39121 tttctgagcc gacaactact ttagaaacca tgtttaggaa aagcccatgt tctactaccc
    39181 caacaagttc atctaaatag gtagctaagc tttctggctg ttcgatgact tctagatgca
    39241 gatcaatgat gtaatgacca ccatctgtgg ttaagacttc tccgttttcg tctgtacgca
    39301 agacgggttg gaatcttttt tcttcaaaaa tatgaagtag ctgttgggag ccataaggga
    39361 tcacttcaac tgggagtggg aacttcccaa gtttatcgac taatttagaa gaatcaacga
    39421 tccaaatcgt ttcttttgag tacgtagcga ctattttctc gaaaagcaaa gcagcgccgc
    39481 cgcctttgat cccttgaaaa tcagcactga tttcatcagc accgtctatt gtcaaatcga
    39541 ctacggggac ttcatcaata ctctttaacg gtattcctaa tttttccgct tgttcttttg
    39601 tcgcatttga agtagtaact cctgtgatac gtaaaccttc ttcacgcata cggcgaccaa
    39661 tctcttctac catataatag gcggttgaac cggtcccgag acctacgatc atcccgtcct
    39721 ttacgaattt cgcggcttca atgccagcta attgttttaa attcatcttt gcgtccacct
    39781 ttttttagtt tgagcatcgt gctttcctca ctattttagc gtgatttacg gtaaaaagat
    39841 accattcttt tttattccaa taaagctttt tcaaaaaaaa ttgcatctct tgttgacatg
    39901 ttttttcatt cgtgatattc taacaaaggt gctttatcta caggtttctg tgaagaaacg
    39961 tgctgactgt ttatcaaagc atatttgata aggatgcaga cattgcattt attttttatc
    40021 acaaaaaaag aaccacctgg atgtgtggaa ctagacgcaa atcgtgggaa ggaggaaaca
    40081 aggaatgcct acaattaacc aattagtacg taaacctcgt aaatcaaagg tggaaaaatc
    40141 taattcacct gctttgaaca aaggatataa cagctttaag aaaactcaaa ctaacgtaaa
    40201 ctcacctcaa aaacgtgggg tagcaactcg tgtgggtaca atgacaccta aaaaaccgaa
    40261 ctcagcttta cgtaaatatg cacgtgttcg tttgtcaaac ttaattgaag ttactgctta
    40321 tatcccaggg attggtcata acttacaaga acacagtgtt gtattattac gcggtggtcg
    40381 tgtaaaagac ttaccagggg tacgttacca tatcgttcgc ggtgctttag atactgctgg
    40441 tgttaacgac cgtaaacaaa gccgttctaa atacggaact aaaaaaccta aagcttaatt
    40501 ttaattatta aacaaatgaa acttgcttct actatataga agtaattact atgaacaata
    40561 tttcggaagg aggagttacg gatgccacgt aaaggtcctg ttgcaaaacg tgatgtttta
    40621 ccagatccta tttataactc aaaattagta actcgcttga tcaaccgtgt aatggttgac
    40681 ggaaaacgcg ggattgcagc taacattatc tataatgcct ttgacttgat caaagaatct
    40741 acaggtaacg atccattaga agtgtttgaa caagcaatga aaaacgttca acctgttctt
    40801 gaagttaaag cacgtcgtgt tgggggttca aactaccaag taccagttga agttcgccct
    40861 gaacgccgcg ttactctagg tcttcgttgg gtagtaaact acgctcgctt gcgcggtgaa
    40921 cacacaatgg aagaacgctt agcaaaagaa atcatggatg ctgcaaacaa cacaggtgct
    40981 tctgttaaaa aacgtgaaga cactcataaa atggctgatg ccaaccgtgc gtttgctcac
    41041 tatcgctggt aagattctct ctgtttggtc ggcttttata agtcgacctc agatagtgtc
    41101 cttattttta gcaactagat agtaaagaga ggagaaacaa ggagaatgac cagagaattt
    41161 tctttacaaa acactcgtaa tatcggtatc atggcccaca tcgatgctgg taaaacgact
    41221 gctactgaac gtatcttgta ctatactggt aaaatccata aaattggtga aactcatgaa
    41281 ggagcttcac aaatggactg gatggaacaa gaacaagaac gtggtattac gatcacttct
    41341 gctgctacta cagcacaatg gaagggtcac cgaatcaaca tcatcgacac accaggacac
    41401 gtagacttca cagttgaagt tgaacgttca ttgcgtgtac ttgatggtgc tgtaactgtt
    41461 cttgatgcac aatcaggtgt tgaacctcaa actgaaacag tttggcgtca agcaacaact
    41521 tatggtgtac ctcgtatcgt atttgcaaac aaaatggaca agatcggtgc tgacttctta
    41581 tattcagtat caactttaca tgaccgtttg caagcaaacg ctcacccaat ccaattacca
    41641 attggtgcgg aagacgactt cacaggaatt atcgaccttg taacaatgaa ggctgaaatg
    41701 tatacaaacg atcttggaac agagatcgaa gaaacagaaa ttcctgaaga ataccgcgaa
    41761 ttagctgaag aatggcgcga aaaattggtt gaagctgtag ctgaaactga tgaagaactt
    41821 actttgaaat acttagaagg tgaagaaatc actgaagctg agttaaaaga aggtatccgc
    41881 cgcgcaacag ttaacgtaga attctaccca gtactatgtg gttcagcatt taagaacaaa
    41941 ggggttcaat tactattgga cgctgttctt gattacttgc catcaccgtt agatatccca
    42001 gctatcaaag ggattgaccc taaaactgat gaagaagtag aacgtcctgc agacgacagc
    42061 gctcctttct cagctttagc atttaaagtt atgactgacc cattcgtagg tcgtttaact
    42121 ttcttccgtg tgtactctgg tgttttacaa tcaggttcat acgtacaaaa cgcaacaaaa
    42181 ggcaaacgtg aacgtgttgg tcgtatccta cagatgcatg ccaactctcg ttcagaaatc
    42241 tctgaagttt acgctggaga tatcgctgct gctgttggtt tgaaagacac aactactggg
    42301 gacacactat gtgatgaaaa gagtctagtt attcttgaat ccatggaatt cccagaacca
    42361 gttatccaag tcgctattga acctaaatca aaagctgacc aagataaaat gggtgtggct
    42421 ttacaaaaac tatctgaaga agatcctact ttccgtgctg aaacaaacgt ggaaacaggc
    42481 gaaacaatca tcgctggtat gggtgaactt cacttagata tcatcgttga ccgtatgcgt
    42541 cgtgaattca aagttgaagc taacgtaggt gcgcctcaag tatcttaccg tgaaactttc
    42601 cgtgctggca ctcaagccga aggtaagttt gtacgtcagt ctggtggtaa aggtcaatac
    42661 ggtcacgtat ggattgaatt tacaccaaat gaagaaggtg ctggtttcga atttgaaaat
    42721 gcgatcgtcg gtggggttgt tcctcgtgaa tacattccag ctgttgaaac tggtttgaaa
    42781 gatgctatgg aaaatggtgt cttagctggc tatccattag tagatatcaa agctaaactt
    42841 tacgatggtt cataccatga tgtcgattca aatgaaactg ccttccgtgt tgctgcttct
    42901 atggcattac gtgcagcagc taagaaagct aatccagtaa tccttgaacc aatcatggct
    42961 gtagaagttg ttatccctga agattattta ggtgatgtta tgggtcacgt aactgctcgt
    43021 cgtggacgtg ttgaaggtat ggaagctcgc gctggcggcc aacaagttgt tcgtgcgatg
    43081 gttccacttg ctgaaatgtt tggttatgct acaactcttc gttctgctac tcaaggtcgt
    43141 ggtacattta caatgacatt tgaccactac gaagatgtac caaaatcagt acaagaagaa
    43201 atcattaaga aaaacggcgg aaaagctgaa taatttcttg aaaccggata gtcctgcaaa
    43261 gagattatcc aaagagacta tatttttaat atagtttcgt gtaaaataat tatcgatgat
    43321 atgggcatgt ggtgtacctt gtgtacatca tatacctatc agacaaataa aaaatatatt
    43381 gtatttttag gaggacattt taaaatggca aaagaaaaat ttgaccgttc taaaccacac
    43441 gttaacattg gtactatcgg acacgttgac catggtaaaa ctacattaac agctgcaatc
    43501 acaactgtac tatctaagaa aaacggcggc caagctatgg cttacgatca aatcgatggt
    43561 gctccagaag aacgcgaacg cggaatcaca atctcaacag ctcacgttga gtatgaaaca
    43621 gatacacgcc actacgctca cgttgactgc ccaggacacg cggattacgt taaaaacatg
    43681 atcactggtg ctgctcaaat ggacggagct atcttggtag tttctgctgc tgacggccca
    43741 atgcctcaaa ctcgtgaaca catcctattg tctcgtcaag ttggtgttcc ttacatcgtt
    43801 gtattcttga acaaagtaga catggttgat gacgaagaat tactagaatt agttgaaatg
    43861 gaagttcgtg acctattaac agaatacgaa ttccctggtg acgatgttcc tgtagttgct
    43921 ggatcagctt tgaaagctct agaaggcgac gcttcatacg aagaaaaaat tcttgaatta
    43981 atggctgcag ttgacgaata catcccaact ccagaacgtg acaacgacaa accattcatg
    44041 atgccagttg aagacgtgtt ctcaattact ggacgtggta ctgttgctac aggtcgtgtt
    44101 gaacgtggac aagttcgcgt tggtgacgaa gttgaagttg ttggtattgc tgaagaaact
    44161 tcaaaaacaa cagttactgg tgttgaaatg ttccgtaaat tgttagacta cgctgaagct
    44221 ggagacaaca ttggtgcttt actacgtggt gttgcacgtg aagacatcca acgtggacaa
    44281 gttttagcta aaccaggtac aatcacacct catacaaaat tctctgcaga agtatacgtg
    44341 ttgacaaaag aagaaggtgg acgtcatact ccattcttca ctaactaccg tccacaattc
    44401 tacttccgta caactgacgt aacaggtgtt gttgaattac cagaaggaac tgaaatggtt
    44461 atgcctggcg acaacgtaac aatggaagtt gaattaatcc acccaatcgc tatcgaaaac
    44521 ggtactaaat tctcaatccg tgaaggcgga cgtacagttg gtgccggtgt cgttacagaa
    44581 atcaaagctt aattcactta agttttaaag taaagcaaca tttattcgga cgtaatcgct
    44641 cggaacgaag gtcttaggat ctttgttccg agctttttta tttattgcag gatcaggaaa
    44701 aaagacagga gtattataaa tagaagaaac acgaaataaa agagtcagta ttttctaaat
    44761 gaaactttat gaaaacaaaa tgttttttac aagaaaaagc cttgctttgt gagtttatat
    44821 atattataat gacaaaggtg cgtttacttt agtgaattgc acagacgtaa tcagaatgat
    44881 ttcgtcggct aagaaacgag aggttgcgac acgcccggac gctttgccac gaacgagcgt
    44941 gacggaaatt ttcgtggagc tatgtctact tttcaaaata ggcgaaggag ggaacaagat
    45001 ggcaaaacaa aaaattcgta tccgtttaaa agcgtatgaa caccgtattt tagatcaatc
    45061 agcggataaa atcgtggaaa ctgcaaaaag aactggagct agcgtgtctg gtccaattcc
    45121 attaccaact gaacgcagtc tttacacaat catccgtgcg actcataaat acaaagattc
    45181 acgcgaacaa ttcgaaatgc gtacacacaa acgtcttatc gacattgtga acccaacacc
    45241 aaaaactgtt gatgctttga tgaagctaga cttaccatct ggtgtaaaca tcgaaatcaa
    45301 attataaaac taaaacaaaa ataatggagg tgtactcatg accaaaggaa tcttagggaa
    45361 aaaagtggga atgacacaaa tcttcactga atctggtgaa ttaattccag taactgttgt
    45421 agaagctact ccaaacgtag tactacaagt gaaaacaatg gaaacggatg gctacgaagc
    45481 tattcaagtt ggttaccaag atatgcgtga agttttatca aacaaacctg cgaaaggtca
    45541 tgttgcaaaa gcaaacacgg ctcctaagcg cttcattcgt gaattcaaaa atgttgagct
    45601 aggagaatat gaagtaggaa aagaaattac agtagatgtt ttccaagcag gagacattat
    45661 tgatgtaaca ggtactacga aaggtaaagg attccaaggg gttatcaaac gccacggaca
    45721 aagccgcgga ccaatggctc acggttctcg ttaccatcgt cgtcctgggt caatgggtcc
    45781 agttgcacct aaccgtgtat ttaaaaacaa acgtcttgct ggccgtatgg gtggcaaccg
    45841 cgtaactatc caaaacttgg aagttgtacg tgtcgatgca gaaagaaatg ttatcttgat
    45901 caaaggtaat gttcctggag ctaaaaaatc tttaattact atcaaatcag ctgtgaaagc
    45961 taaataattg taggaagaaa ggaggaacta aggaatgccg aatgtagcat tattcaaaca
    46021 agatggaagc caaaacggtg aaatcacact taacgaagaa atcttcggaa ttgaacctaa
    46081 tgaaagtgtt gtttacgatg caatcgtaat gcaacgtgcg tcattaagac aaggaacaca
    46141 cgcggttaaa aaccgtagcg ctgttcgcgg cggcggacgt aaaccatggc gtcaaaaagg
    46201 aacaggtcgt gcacgtcaag gatctatccg ctcaccacaa tggcgtggag gtggcgtagt
    46261 ctttggacca acaccacgtt cttacagcta caaacttcct aaaaaagttc gtcgtttagc
    46321 aatgaaatct gtattgtcag aaaaagttgc tgaaaacaac ttggtagcaa tcgaaggctt
    46381 gaacttcgac gcaccaaaaa caaaagaatt caaacaagtt cttgctaact tatctatcga
    46441 ctctaaagta ttggttgttc tagaaaaagg taacgacttt gctgctttat cagcacgtaa
    46501 cttaccaaac gtttctgtag taacttctga taatgtgagt gtgctagacg ttgtatcaaa
    46561 tacaaaagtg ttagcaacac aaactgctct tactcaaatt gaggaggtgc ttgcataatg
    46621 aacttactag acgtaatcaa acgcccagtg atcactgaaa aatcaatgct tgccatggat
    46681 gacaagaaat acacttttga agtggacact cgcgcaaaca aaactttagt aaaacaagcg
    46741 gtagaagctg cttttgacgt taaagtcaaa aacgtgaaca tcgtgaacgt acgtgcgaaa
    46801 ttcaaacgta tgggcaaata tgcaggatat acaaaaaaac gtcgcaaagc gatcgttaca
    46861 ttgactgaag attcaaaaga aatccaatta ttcgaagctg ctgaataagc actaatagat
    46921 aactcattaa attaggaggg aaaaacgtgg cgattaaaaa gtacaaacct acctcaaatg
    46981 gtcgtcgtaa catgacaggt tctgattttg ctgaaatcac aacatcaaca cctgaaaaat
    47041 cattgttaca accattgaaa aaccatgctg gacgtaacaa caacggccgc atcactgtac
    47101 gtcatcaagg tggcggacac aaacgccaat atcgcgtgat cgacttcaaa cgtaacaaag
    47161 ataacgttgt tgcaactgtt caaacgatcg aatatgatcc aaaccgttca gctaacatcg
    47221 cgttagtaca ctatgaagat ggagtgaaag cttacatctt agcacctaaa ggactagaag
    47281 tgggtatgaa acttgtttca ggtccagaag cagatatcaa agtcggaaat gctcttccat
    47341 tagaaaacat tccagttggt actgttatcc acaacattga aatgaaacct ggtaaaggtg
    47401 gacaattgat ccgttctgct ggtacaagtg ctcaagtact tggtaaagaa ggcaaatacg
    47461 tattgatccg cttgaactct ggtgaagttc gtatgatctt agctgcatgc cgtgctacaa
    47521 tcggttctgt aggtaacgaa caacacgaat taatcaacat cggtaaagct ggacgctctc
    47581 gttggatgcg taaacgccca actgtacgtg gtagcgtaat gaaccctaat gatcacccac
    47641 acggtggtgg tgaaggtaaa gctcctatcg gacgtaaagc accagtttct ccttggggtc
    47701 aaccagctct tggttacaaa actcgtaaca aaaaagctaa atcagacaaa cttattgttc
    47761 gtcgtcgcaa aaataaataa ttactttgac catgtgtcgc acattttgag aggaggttca
    47821 ccatgggtcg tagtttaaag aaaggacctt ttgtcgatga gcatttaatg aaaaaagttg
    47881 aagctcaagc aggggttgaa aagaaaaaag ttatcaaaac ttggtcacgc cgttcaacag
    47941 ttttcccaag ttttgttgga tataccatcg cagtttatga tggacgtaaa catgtaccag
    48001 tttacatcca agaagacatg gtaggacaca aattaggtga atttgcacct acaagaactt
    48061 atcgtggaca tgctgctgac gataagaaaa cgaaacgcta atttgagggg aggataaatc
    48121 caaatggcag aacaaatcac atcagctaaa gcaactgcaa aaacagttcg cacttcacct
    48181 cgaaaagccc gtttagtaat tgaccttatc agaggtaaaa gtgtcgcaga tgcaatttca
    48241 atcttgaaat tcacaccaaa caaatctgct ggaatcattg aaaaagtatt gatgtcagca
    48301 gttgcgaatg cagaaaataa ctttgactta gatgttgaaa acttggtagt aagcgaagct
    48361 tttgttaacg aaggacctac aatgaaacgt ttccgtcctc gtgcaaaagg atcagcttct
    48421 ccaatcaaca aacgtacaag tcatatcacg gtagtcgtat cagaaaaata aggagggata
    48481 atcagtgggt caaaaagtac atccaattgg aatgcgtgta ggcatcatcc gcgactggga
    48541 tgctaaatgg tatgctgaaa aagagtatgc tgagttctta cacgaagatt taagaatccg
    48601 taaatttatt tcaactaaac ttgctgatgc tgctgtatca acagttgaaa tcgaacgcgc
    48661 aacaggtcgc gtaaacattt caattcacac agctaaacca ggtatggtta ttggtaaagg
    48721 cggttctgaa gtcgaaagcc taagaaaaga attaaacaaa ttaactggta aaagaatcca
    48781 tatcaatatc gtggaaatca aaaaaccaga tctagatgca aaattagtag gtgaaggaat
    48841 cgcacgtcaa ttagaaaacc gtgttgcttt ccgtcgcgct caaaaacaag ccatccaacg
    48901 ctcaatgcgt gctggcgctc aagggatcaa aactcaagta tctggtcgtc taaacggagc
    48961 agatatcgct cgttcagaag gatactcaga aggaactgtt cctcttcata ctttacgtgc
    49021 ggacattgat tacgcatggg aagaagcaga tacaacatac ggaaaactag gagttaaagt
    49081 gtggatctat cgtggagaaa ttcttccaac taaaaaaaac actgagaaag gagggaaata
    49141 atcatgttag tacctaaacg tgtaaaacac cgtcgtgaat tccgcggaaa aatgcgcggg
    49201 gaagctaaag gcggaaaaga agtagcattc ggtgaatacg gtttgcaagc tgttgattca
    49261 cattggatca caaaccgcca aatcgaagct gctcgtatcg caatgactcg ttacatgaaa
    49321 cgtggtggga aagtatggat taaaattttc cctcacaaat cttatactgc caaagcaatt
    49381 ggggtacgta tgggttctgg taaaggggca cctgaaggat gggttgcacc agtaaaacgt
    49441 ggtaaaatca tgtttgaaat cgcaggcgtt cctgaagaag tagctcgtga agcgttacgt
    49501 ctagcttctc acaaattacc aatgaaaact aagatcgtaa aacgtgagga aatgggtggt
    49561 gaatcgaatg aaggttaaag aaatcagaga attaaccact gccgaaatgc ttgatcaaga
    49621 aaaacaatta aaagaagaat tgtttaatct tagattccaa ttagcaacag gtcaattaga
    49681 aaacactgca cgtattaaag aagtacgtaa atcgattgca cgcatcaaaa ctgtgttgcg
    49741 tgaacaagct aagtaattat ggaaggaggc cattaagcgt atgactgaag gaagaaatca
    49801 acgcaaagtt tatcaaggtc gcgtggtttc agacaaaatg gataaaacaa ttaccgttgc
    49861 tgtcgaaaca aagaaaaacc accctatcta tggcaaacgc atgaactatt ctaagaaata
    49921 caaagtgcat gatgaaaaca acacagcaaa agttggcgac atcgtgagaa ttatggaaac
    49981 tcgtccatta tcagctacaa aacgtttccg tttgttggaa gtagtcgaag aagcagttat
    50041 tatctaataa cacgagattt tcctatatag attgaatgca aaatctgaaa ggaggataca
    50101 caacgtgatc caagcagaaa gtcgtttaaa agtcgctgat aactcaggcg cacgtgaaat
    50161 tttgacgatc aaagtccttg gtggatctgg tcgtaaaact gctaacatcg gtgatgtgat
    50221 cgttgctacg gttaaacaag caacgccagg tggggttgtc aaaaaaggtg acgtcgttaa
    50281 agccgttatc gttcgaacaa aatcaggagc tcgtcgtaca gacggttcat atattaaatt
    50341 tgatgaaaat gctgcagtga ttattcgtga tgataaaagc cctcgtggaa cacgtatctt
    50401 tgggccagtt gcacgtgaac tacgtgaaaa caacttcatg aagatcgttt cactagcacc
    50461 agaagtttta taatcttgag acacttatca aaggaggtgc gaaacagtta tgtttgttaa
    50521 aaaaggcgat aaagttaaag ttatcactgg aaaagacaaa aacaaagaag gcgttgtact
    50581 agcagcgttc ccgaaaaaag ataaagttat tgtcgaaggt gtaaatgtcg ttaaaaaaca
    50641 ccaaaaacct tctcaagctg ctcctcaagg tggaattgtt gagatggaag cgccaattca
    50701 tgtttctaac gtgatggtgg ttgactctac tggtgtagct ggccgagttg gctacaaaga
    50761 agtagacggc aaaaaagtcc gtgtttctaa aaaaaccggt gaagttttag ataaataaaa
    50821 gtttaaggaa ggagggtctt actgaatgaa ccgcctaaaa gaaaaatatc ttaaagaagt
    50881 aactccatca ttgatggaaa aatttaacta tagctctgtt atgcaaacac ctaaagttga
    50941 aaaaatcgtc atcaacatgg gtgttggtga tgcggtatca aacgctaaaa acttagataa
    51001 agcagttgaa gaattaactt tgatcactgg tcaaaaacca atgattacaa aagctaaaaa
    51061 atcaatcgct ggattccgtt tacgtgaagg aatgccaatt ggtgcaaaag ttacattgcg
    51121 cggagaaaga atgtacgaat tcttagacaa attggtttct gtttcactac cacgtgtacg
    51181 tgacttccat ggtgtaagta aaaaagcctt tgacggtcgt ggaaactata ctttaggtat
    51241 taaagaacaa ttgatcttcc cagaagtaga ttatgattta gtagataaag tacgtggtat
    51301 ggacatcgtt attgtaacaa cagcaaactc tgatgaagaa tctcgtgagt tgttgacaca
    51361 attaggcatg ccattccaaa aataattaaa ggaggcgaac tacgtggcta aaaaatcaat
    51421 gattgctaaa aacaaacgtc ctgcaaaatt ttcaacacaa gcttatactc gttgcgaacg
    51481 ttgcggacgt ccacattcag tttatcgtaa gttccatctt tgccgtattt gcttccgcga
    51541 acttgcctat aaaggtcaaa ttcccggcgt gaagaaagct agctggtaaa aagtaaattc
    51601 gcataagaag gaggtaaaag atcaatggtc atgacagatc caattgcaga ttttctaact
    51661 cgtatccgta acgcaaacat ggttaaacat gagtctttag aagtacctgc atcaaaaatt
    51721 aaacgtgaca tcgctgaaat cttgaaacgt gaaggtttcg ttcgtgatgt tgaatacatc
    51781 gaagatgaca aacaaggcgt gatccgtgtt ttcctaaaat ttggtaaaaa cggcgaacgt
    51841 gttatcacaa acttaaaacg tatctctaaa ccaggtttgc gtgcttatgt caaagctgac
    51901 gaagtaccaa aagtattgaa cggtttaggt atcgcaatca tttcgacttc tgaaggtgtt
    51961 gtcactgata aagaagctcg tgaaaaaaat atcggcggcg aagttatcgc ttacgtatgg
    52021 taatcaagta gaatctacaa ggaggtgtct ttaagtgagc cgtatcggaa ataaagtcgt
    52081 tgttatccct gaaggagtaa cagttactca agacggaaac aacgttacag ttaaaggacc
    52141 aaaaggtgaa ttgactcgta ctttttcagc agatatcaaa atgaatatcg aaggaaacga
    52201 agtaactttc actcgtccaa acgacagtaa agaaatgaaa acaattcatg gaacaactcg
    52261 tgcgaacttc aacaacatgg ttgtaggtgt cagcgaaggt ttccaaaaag cgttagaact
    52321 aatcggggtt gggtaccgtg cacaattaca aggatcaaaa cttgtattga acgttggtta
    52381 ctcacatcca gtagaaatca caccaccagc tggagtaact gttgaagtac cagctaacac
    52441 acaagtaatt gttaaaggtg cgaacaaaga agaagttggc gaattagctg caaacattcg
    52501 tggaactcgt cctccagaac cttataaagg taaaggtatt cgttatgttg gcgaatatgt
    52561 acgccgtaaa gaaggtaaaa ctggtaaata atcgtttaga aaaattgcat agaagccagc
    52621 agcaggaaaa aggcatttgg ctgaagttta ccttcaaaaa aatacatttt tacttgtgcc
    52681 gcagcttcta tttttcgaaa cgtatttact gcttgaaata gtagtacaat aaaaataaag
    52741 aggtgacaat tgtgattaca aaaccagata agaacaaaac acgtcaaaag agacatcgtc
    52801 gtgtacgtaa caatatctct ggtactgctg agcgcccacg cttgaacgtt tttcgttcta
    52861 acaaaaacat ctacgctcaa attattgatg acgtagcggg tgtaacgcta gcaagtgcct
    52921 ctaccttgga taaagaaatt tcaggtggaa caaaaacaga agcagcacaa gctgtcggta
    52981 aactagttgc tgaacgtgca gctgaaaaag gcattaaagt agtagtcttt gaccgtggtg
    53041 gataccttta ccatggccgt gtgcaagctt tagctgaagc tgctcgcgaa aatggactag
    53101 aattttagaa gaaggaggaa taccattcat ggtttatatc gatccaaaac atttggaatt
    53161 agaagaccgc gttgttgcaa ttaaccgtgt aacaaaagtt gttaaaggtg gacgtcgtct
    53221 acgttttgct gctttagttg ttgtcggtga caaaaacgga cacgtagggt ttggtacagg
    53281 taaagctcaa gaagttcctg aagcaatccg taaagcaatt gaagatgcga agaaaaactt
    53341 agttgaagta cctatggttg gttcaacaat cccacacgaa gtaatcggtg cttttagtgg
    53401 tggtagaatc ctaatgaaac ctgctgtaga aggttctggg gttgctgctg gtggaccagt
    53461 tcgtgccgta ttagaattag ctggggtagc agatatcact tctaaatctt taggctcaaa
    53521 tacaccaatc aacgttgttc gcgcaacagt tgaaggtttg aaacaattga aacgtgcaga
    53581 agaagttgca gaacttcgcg gcaaatcagt tgaagaatta atcggataag gaggacaaca
    53641 ataatggctg aattaaaagt tactttaaaa cgcagtatta tcggacgtcc tcaaaaccaa
    53701 cgcgatacag ttaaagcgtt aggtcttaca aagattaaca gttcagtggt taagccttct
    53761 aatgaagcaa ttaaaggcat gatcaatact gtttctcacc tagtggacgt tgaagaaatt
    53821 taatttagaa aaatcataac tagaacatta aggaggtgcc aaacctatga aacttcatga
    53881 attaaaacct gctgaaggtt cacgccaagt acgtaaccgt gttggtcgtg gtacttcatc
    53941 tggtaacgga aaaactgccg gacgcggaca aaaaggacaa aaagctcgtt caggcggcgg
    54001 tgtgcgttta ggatttgaag ggggacaaac accattgttc cgtcgtttac caaaacgagg
    54061 attcacaaac gtgaaccgta aagactatgc agtcattaat cttgatgtat tgaaccgctt
    54121 tgaagacgga gctgaagtaa ctcctgttgc tttagttgaa gctggaatcg tgaaaaacga
    54181 aaaagctgga atcaaagtat tagctaatgg ggaactaaac aagaaattaa ctgtgaaagc
    54241 agcaaaattc tctaaagcag ctcaagaagc aattgaagcg gctggtggat caatcgaggt
    54301 gatctaatgt ttagactatt aaaagatgct tttaaagtaa aagacattag atcgaaaatc
    54361 ctatttactg tatttgtgtt gtttgtattt cgcctaggtg cacatattac tgtaccaggc
    54421 gtaaatgctg cttcattgca aaacctttct tctttgccat ttttcaacat gttgaacttg
    54481 gtaagtggta gtgcgatgca aaacttttcc attttctcaa tgggggtttc accatacatt
    54541 actgcttcta tcgtcattca gcttcttcaa atggacatcg tgcctcgatt tgttgaatgg
    54601 tcgaaacaag gggaagttgg tcgtaaaaaa ctgaatcaag cgactcgata tctgacatta
    54661 gtattggcat ttatccaatc tgtcggtatc actgctggat tcaatcaata cgctcaatta
    54721 ggtttcgtga ataatcctaa cgtagcaact tacgtaacga tcggtttgat tctaacagcc
    54781 ggtacgatgt ttgttacttg gctaggagaa cagatcacag aaaaaggtat cggaaatggc
    54841 gtatcaatga tcatttttgc aggtatcatt tctagattgc ctgaaagtat cagagaaatt
    54901 tatgaagatt actttataaa tattgatcct tcagacatat ggaaatctgc tatttttgtg
    54961 gccattttac tagtagcggt cttgttgatc gtgacattcg taacattttt ccaacaagct
    55021 gaacgcaaga tcccgatcca atatacgaaa cgcgtagctg gcgcgcctac aagcagctat
    55081 ctgccgttga aagtaaatgc agctggagtt attccagtta tctttgctag ttcgtttatt
    55141 gctacgccaa atgctgtttt acaagcattg agcggtagat tcggttctga aaactggtac
    55201 aaagtgatga tggagatctt taactataat acagcacctg gtgctacgat ttatacgatt
    55261 ctgatcgttg ccttcacttt cttctacgcc tttgttcaag taaaccctga gaaattagcg
    55321 gaaaacttgc aaaagcaagg aagttatata ccaagcgtac gccctggtaa ggggactgaa
    55381 gagtatgtct caagattact gatgcgttta agtacagttg gtgcagtctt ccttggttta
    55441 gtggcattgc ttccaatcat tgctcaaatg gtttgggatc ttccacaatc aatcggatta
    55501 ggcggtacaa gcttactgat cgttatcggt gtagctttag aaactgcgaa acagttagaa
    55561 ggcttaatgc tgaaacgtaa atatgttgga ttcattgagt aagaaagcgt gttgaggttt
    55621 cccctcaaca cacgttctca cacatttatt aggagggaaa acaatgaacc tcattttaat
    55681 ggggctgcca ggcgcaggta aaggaacaca agctgaaaaa atcattgatg cttatggtat
    55741 tccgcacatc tcaacaggag atatgttccg cgcagcgatg caaaacgaaa cagctcttgg
    55801 cctggaagca aagtcttata tggataaagg tgcattagtt cctgatgaag taacaaatgg
    55861 aatcgtgaaa gagcgactag ctgaaccaga tacagagaaa ggcttcttat tagatggctt
    55921 tccacgtacg ctagatcaag caaaagctct ggacgcaatg ctaaaagatt tgaataaaaa
    55981 aattgatgct gtcatcgata tccatgttgg tgaagaaatc ttggtcgaac gtctagccgg
    56041 ccgatttatc tgcagcaatt gtggagcaac ttaccataaa attttcaacc ctacaaaagt
    56101 tgaagacaca tgtgatcgtt gcggtgggca tgaattctat caaagagaag atgataaacc
    56161 tgagacggtt aaaaatcgtc tggctatcaa catcaaaaat agtgaaccaa tcttggctta
    56221 ttataaagaa caaggtttgc taaacactat tgatggtgct cgtgaaatcg atgctgtatt
    56281 tgcagatgta caaaaaatca ttgaaaaata gcacgattgc ccgtagccga cttgcattat
    56341 gcagttactc ttgtcaagtt caataaatta tgatagaata tgtcagtccg acttctagag
    56401 aatcctctag atgatccatt ttgagaattt tgaggtggga actgcagttt ccgccatttt
    56461 atcgtgtgaa aatgcgaaac aagtacaagg aggtactgtg cgtggcaaaa gaagatatga
    56521 ttgaagtcga aggtacagtc gtcgaaactt tgccgaatgc aatgtttaaa gttgaactag
    56581 aaaacggaca ccaagttctt gctactgttt caggtaaaat tcgtatgcat tacatccgta
    56641 tcttacctgg tgacaaagta acggttgaat tgtctccata cgatcttaac cgtggccgta
    56701 ttacttatcg ctttaaataa ttgtactccg taaaactaca ggaggtatta tcatgaaagt
    56761 aagaccatca gtaaaaccaa tgtgcgaaca ttgtaaagta attcgtcgta aaggacgcgt
    56821 tatggtgatt tgcccagcaa atccaaaaca taaacaacgt caaggataat tggaggtgct
    56881 ataaatatgg ctcgtattgc aggagtagat attcctcgtg ataaacgtgt agtagtttca
    56941 cttacttata tctatggtat tggtaacact actgctaaaa agatcttagc tgatgctggt
    57001 gtatctgaag atgttcgcgt tcgtgaatta acgaatgaac aaacagatgc tatccgtgca
    57061 gaagtagata aattaaaagt tgaaggggat cttcgtcgtg aagtgaactt gaacatcaaa
    57121 cgtttgatgg aaatcggttc ttaccgtgga atccgtcatc gccgtggatt gcctgttcgt
    57181 ggacaaaaca cgaaaaacaa tgcacgtact cgtaaaggcc cagctcgcgc tatcgctggc
    57241 aagaaaaaat aattcttaag tgaaggaggt taaaacttca tggcagcaaa aaaagtgaat
    57301 cgtaaacgcc gtgtgaagaa gaatatagaa gcaggtattg cacatatcca ttctacattc
    57361 aataacacta tcatcatgat cactgatact cacggaaatg cattagcgtg gtcatcagct
    57421 ggttcattag gtttcaaagg aagcaaaaaa tcaactcctt ttgccgctca aatggcagca
    57481 gaaactgcta caaaagcagc aatggaacac ggattaaaga ctgttgaagt aacagttaaa
    57541 ggacctggtt ctggacgtga agcagcaatt cgttcattac aagctacagg tttagaagtg
    57601 actgcaattc gtgacgtgac tccagttcct cataatggtg cccgccctcc aaaacgccgt
    57661 cgtgtttaat gagtgccgct cattttgagt tttatcagta acgtcattga acaagacact
    57721 tttcgttttg aaaggggtaa agataagaat gattgagttc gaaaaaccaa gaatcgcaaa
    57781 aattgatgaa gaaaaagatt atggcaagtt catcgttgaa cctcttgaaa gagggtatgg
    57841 gactacttta gggaattccc tacgtcgtat tttattatct tctttgccag gtgctgccat
    57901 cactaatatt caaatcgatg gtgtactgca tgaattctct accatcaaag gtgttagaga
    57961 agacgtcact caaatcatct tgaacattaa aggcttagcg ctgaaaatgt atggccaaga
    58021 agaaaaaacc cttgaaatcg atattaccgg acctgctaca gtaactgctg gcgatattat
    58081 cgttgatagt gatgtagaaa ttcttaacaa agatatgtac atctgtagtg tctctgaagg
    58141 agctacgttc catgctcgct taacagtgaa acctggacgt ggttatgttc aagcagatga
    58201 aaataaaaaa gaagatatgc caattggcgt tcttccagtc gattcaatct acacacctgt
    58261 tcgtcgtgtg aactatcaag ttgagaacac acgtgttgga caccgtgaag attttgataa
    58321 attgacgatg gagatttgga cagatggttc aattgaaccg ttggaagcaa tgagtttgtc
    58381 tgcgaaaatc atgactgaac atttggatat ttttgtgaac ttaactgatg aagcaaaaaa
    58441 tgctgaaatc atggtcgaaa aagaagaaac acaaaaagaa aaaatgttgg aaatgacgat
    58501 cgaagagtta gacttgtctg ttcgctctta caattgtttg aaacgtgcag gaatcaatac
    58561 tgtacaagaa cttacaaata aatctgagcc tgaaatgatc aaagtccgta acttaggacg
    58621 taaatcatta gaagaagtta aagcaaaatt gcacgactta ggtttaggtt tacgtaaaga
    58681 agattaaaac cttttacgaa ggagggaaac caacgtgagt tatcgtaaac taggacgcac
    58741 atctagccaa cgtaaagcga tgttgcgtga tttaacaact gatttattaa tcaacgaacg
    58801 tattgtgact actgaagctc gtgcgaaaga agttcgctca actgcagaaa aaatgatcac
    58861 tttaggtaaa cgcggagatt tgcatgcacg tcgtcaagct gcggctttcg tacgtaatga
    58921 agttgccagc gtgcgtgaag aaaatgagga catcgtcatt gaatcagctt tacaaaaact
    58981 gttcaacgat attgcacctc gttacgcaga acgtcaaggc ggatacacac gcattttgaa
    59041 gacagaacca agacgcggtg atggtgcacc aatggttgtc ttagaacttg tctaaaatca
    59101 cactaataac atcactttat agatgattct tttagagtgt tatgatgttg gaagatattt
    59161 ttccgagtct agctcagcgc tgctcctcaa gcgaatatcg cttggggagt aagcactcat
    59221 cataaagtgt ttttttatac cttcaattac ctgtcatgac agatatgttt gaaggcataa
    59281 aaaaacattt taagcgagaa ataattgaaa attttgtctt tttttgatag tgttagtagg
    59341 aactttagga tgaagaagga gtaatcatgg agccaattat tgaattagaa aagataaatt
    59401 ataaatacca gccagatgat cttcgccccg cattgaaaga tgtctccttt acaattgata
    59461 aaggtgagtg gatcgctatt attggacaca atggttcagg aaaatcgaca cttgccaaaa
    59521 cgatcaatgg attgcttctg ccagaatcag ggatcgtgaa agtgggaaat caaatattgg
    59581 atgaagaaaa tatttggacg atccgacaga tggttggaat ggtttttcaa aatccagaca
    59641 atcagtttgt tggttcgaca gtagaagatg acgttgcttt tggtcttgaa aatcaaggga
    59701 ttcccagaga agaaatgcta gtgcgtgtga aagatgcact tgagaaagtt agaatggctg
    59761 agtttgcttc acgcgagcct gctcgtttat caggagggca aaaacaacgt gttgccattg
    59821 ccggcgtggt tgccttacga cctgatatca ttattttaga tgaagcaacc agtatgctag
    59881 atccagaagg tcgtgaagaa gtgatctcta cgatcaagaa gatcaaagaa gaaagtcaat
    59941 tgaccgttat atctatcact catgatattg atgaagcagc taatgccaat cggatactag
    60001 tgatgagaca aggcgaactt gtccgtgaag gtacaccaaa agaaattttt tctgctggtc
    60061 ctgaactgat cgacttaggt ctagatctac catttcctga aaaactgaag agcgcactga
    60121 aagaacgtgg ggttgatgtg cccagtgaat atatgacaga agaaaggatg gtggattggt
    60181 tatggacatc cgttttgaac aagtagactt cacttatcag ccgaatacac catttgaaca
    60241 aagagcctta tttgacatca atatgacgat caaagaaaac agttatactg cattagtagg
    60301 gcataccgga agcgggaaat caaccttact tcagcatttg aatgcgcttg ttaagccaac
    60361 aagcggtaca gtccatattg gagaacgaga tattcagccg gatacggata ataagaattt
    60421 aaagcccatc cgaaaaaaag ttggcatcgt ctttcagttt ccagaagcac agctattcga
    60481 agaaacggta gcaaaagaca ttgctttcgg tcctaaaaac tttggtgtca gcgaagaaga
    60541 agcactagtc ctagcaaaag aaacattaga acaagttggg ctggatgaaa gctatttgga
    60601 acgttcgcca tttgaacttt caggagggca aatgcgtaga gtagcaatcg ctggtgtgct
    60661 tgccatgagg ccggaagtac ttgtattgga tgaaccaacg gcaggacttg atccccaggg
    60721 tagaaaagaa atgatggaga tgttttggcg tcttcataag gaacagcaga tcactattgt
    60781 attagttacg catttaatgg atgatgtagc caattttgca gattatgtct atgtgttgga
    60841 aaagggacga atcgttaata gcggggagcc gcaagaggtc tttcaaaaca ttgaatggct
    60901 aaaagaaaaa caactaggcg tacctactgc caccgagttt gcagaagaat taatggctaa
    60961 agggatgaac tttgctacct tgcctttgac agctgaagaa ttagcagacg ctatcgtcca
    61021 ttatgctgga ggaaatgccc atgatgaata aattgatatt tggtcgttat atgcctggag
    61081 attccttgat ccatcgattg gatccccgag ctaaattatt agccagtttt tattttatcg
    61141 gaatcatttt tttagcaaat aattgggaaa cgtacctttt gttggcattt ttcacattac
    61201 tttctgtctt cttgtcaaaa gtagatttga aattttttat ccgaggcatt cgcccattga
    61261 tctggctaat cctcttcact gtagctttgc aggtcttgtt tacaagtggc ggagaaactt
    61321 attggagttg gggtgttttc catatcactg aatttggtgt gatgaacggc ctctttattt
    61381 tctgtcgatt cgtgttgatc atttttatgt cgactctact cacgcttact acaccgcctt
    61441 tggaattatc ggatgcgatt gagtacttgc ttcgtccatt gaaagccgta cggttcccag
    61501 tccacgaaat ttcattgatg ctgtcgattg ctcttcgttt tgtgcctaca ttgatggacg
    61561 aaacagaaaa gatcatgaac gctcagcgcg ctcgcggtgt tgattttggt gaaggaaacc
    61621 tagttcagaa aatgaaagca gtcattcctt tgctgattcc tttatttgtc agcagcttca
    61681 accgtgcgga agatcttgcg actgctatgg aagcaagagg ctacaaaggt ggggaaggaa
    61741 gaacgaaata tcgtgtattg cattggcata atagagacac gatggttatc attgcttttg
    61801 tattattaac tgtgctactg atctttttga gaggataaac gttcagtggg ccgctatcta
    61861 ttcttttctt gctgatctgt ttgcaagaaa ggatgcgagc agtgtatgac aagaaatatt
    61921 agggtctgtg gcagactaag gtcacaggcc tctttctttt atctgaaaag aaagaacgaa
    61981 aaaattttat aaaaaaatca ttattccaga taacctttta ggaacaaagg agagaaaaac
    62041 atggtacgtt acaaagcaat cattgcatac gacggaacaa attttaatgg attccaaaaa
    62101 cagccaaatg ggcgtactgt tcaagaagaa gtagaaaaaa cattacaaaa aatggcaaat
    62161 ggaaaagaaa tcacggtctt tggttcggga aggacagatg ccggagtaca tgcgattggg
    62221 caagtaatcc attttgatta tccagaggag cgtccgttag aacgaatgcg tttcgcgcta
    62281 gatacccagt caccagagga tattgctgta agacaagtag aaattgtttc agaagacttc
    62341 cacgcaagat atttggtcaa agaaaagacg tatcaatttc gagtggatat agggaaacca
    62401 cgcagtcctt ttcgacgcca ttatgcaagt tattttcctt accctcttga tttggaaaaa
    62461 attcagcggg cgcttcctga tttattaggg actcacgatt tcacctcttt ttgtgcatca
    62521 ggaagctcga tagaggataa agtacgtacg atctacgagg ctaagatgga ggtaaatgaa
    62581 acaaaagacg aattgttgtt tacatttagg ggaaatggct tcttgtataa gatgatacgg
    62641 atcttagtag gaacgctttt gaaaattggc aatggccgat tgcctgaaga tagtatccca
    62701 gatattattg cgaaaaaaga tcgtaatgca gcaggaccta cagcacatcc tgaaggactt
    62761 tatttgtatg aagtgaaata tgaataagag gttgtgacag aagtggtcag cttcaagaaa
    62821 taagaaggaa tttacgaaaa ttacttctca aaattttgca aaatttcggc ttattttcga
    62881 aggagctact tctggaacac cgtgaatcag aggttgtgaa aaagctgccc tgcatcaagt
    62941 aataagaaca accaaacaaa aatagctcgt catatttttc gtttggttgg gcttattacc
    63001 gcagatgcaa gcttttgaac accgtttaag gaagaggttg tgaaatcagc gttttgacct
    63061 gagtattaga gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttg ttgagctaat
    63121 accgaaggtc agctgattga acaccgttta agaaagaggt cgtgagcctg tcatttaact
    63181 ctgagtcaca agtaacaatt tcaaaaaaca gcttctcatc tttgatgaat atcgtgactt
    63241 gtggacgagg cgttgataag tgaatcatct ttttgttacc tattttttct gtaaccaaaa
    63301 aacgatggaa cgttgttttg attgccctta atgaggacag tcggaacagg tttgtcattt
    63361 ttatatttaa atggcacaaa tttttctaat tatttgtcat ttagcgctga aaatttttgc
    63421 tatttatcta aaaaagtgat aactacttaa gatgaagcag aatatttacg ccatacggca
    63481 tacaaccgcg aaaaatataa aaaaaagaaa acgattgaac gcgtttttgc agtcgcaaag
    63541 gaaaagcatg gaatgcgcta catcaagtat cgagacttgg aaaacaatca ggtgtatacg
    63601 ctgattgttt ttgctgcaat gaatctgaaa aagttgtcca cttggcagtt ggaacatatg
    63661 tcttcatatc ttttattata caaaaatagc aaaagcacca gtctacactc ttagtaaaga
    63721 ggaaactgat ccttttgtct acattcttaa agtacttaaa ctaagtactt tattttactc
    63781 tttaggattg atacagtagc atctatccct ttattaataa tcttttattt ttttaaataa
    63841 agatgttgtc tccatcttca ggcactaaaa ctttttcgga aattcctttt tctttattga
    63901 aagactttaa ttcttctctt gacagtcccc aatggtttac agcttccata tgaacggcaa
    63961 taattgtgga atctggtatt gctttatgca attcatataa atcgtctttc cccataataa
    64021 gagattctcc aactaaaaaa tgattatctc cagcatttgc tactatgatt tctggattat
    64081 actgatcaat agtttgttta acagcttcat accaaactgt atctcctgta aagtatagtg
    64141 tcttctcagt cgaatgtttg aaaacaatac cgcaaacatt acctacataa ttcaagattt
    64201 ctcctctgcc atgtttgcct tttgttttaa ccaattgtat agattcaaaa actgtgtctt
    64261 ctcgtagtac ctccacattt ttaaaaccat atagtcgaat ttcattcgca tcattttcat
    64321 cttgcacaaa taattttatt tctttaggta ggacctcttt cgctatatcg tcccaatgat
    64381 ctagatgtaa atgtgttaca ataacagcat caataccgtt gataatatct tcgactggca
    64441 ttggcaaatc aactagagga ttcatttgat cttttcttgg tgatggaaaa ggacctttcg
    64501 aaataaatgg tggaagtgtt cctttttccg ctaacattgg atcaattaaa aattttttac
    64561 ctccatagtc taagatagct gttgcattac gaatgtgatg tatattcata aacgttgtct
    64621 cctttttgtt gatatgaaat atttttagta taattcaatt ccatacaata aataaaccga
    64681 acaaaaaaag tcttttacta tttttactta atttatgaaa ggttgtttac catgttagac
    64741 caaacagata taaatatcat tgaggaacta tcaaaaaata gtcgaatcac aatgaaagaa
    64801 cttggagaaa aagtacattt gactggaccc gctgtctcgg cgagagtgac aaaactagag
    64861 gaaagtggag ttattgaaaa ttatacagta aaattaaata tggaaaagct agggttttcg
    64921 attcacgctt ttttaattat aattacgcaa aatttaaatc ataaacccta tttatcattt
    64981 attaaaaatc atgaaaaatt cttgattaga aattataaga ttagtggagg gggctgttat
    65041 cttttggaat gtagatttac ttcaaaaaaa tcaatgaaca gctttttgga acagcttaat
    65101 gaatatgcga attataaatt atctattgtt atagattaat aataaaacta gcagatggta
    65161 aaaatactaa tatgcgagac acacattcaa ccataactat ataacttatc aatttaaaac
    65221 taaactgatg gaaacaagta aggcaaaaac atttatattt tgccctactt atttttttaa
    65281 ttaaattcat tgatgattca tatttagaaa attctatgaa ggccaaatga gtatcctgtc
    65341 acttttttag ataaatagca aaaattttca gcgttaaatg acaaataatt agaaatattt
    65401 gtgccattta aatataaaaa tgacaccaag tatatcatga acgcacaaaa agaccaacag
    65461 ggtataccct gttggtcta
//
LOCUS       DBBGSP010000010        65020 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000010 DBBGSP010000000
VERSION     DBBGSP010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 65020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65020
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.010"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(1..120)
                     /locus_tag="ACIZE9_000759"
     CDS             complement(1..120)
                     /locus_tag="ACIZE9_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGC6092643.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            299..1960
                     /locus_tag="ACIZE9_000760"
     CDS             299..1960
                     /locus_tag="ACIZE9_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6092644.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSAALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2392)
                     /locus_tag="ACIZE9_000761"
     CDS             complement(2030..2392)
                     /locus_tag="ACIZE9_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HGC6092645.1"
                     /translation="MKEQSNEKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFL
                     WSLPFLIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLII
                     AGILIALSAIFMLFSLLG"
     gene            2460..3401
                     /gene="opp3b"
                     /locus_tag="ACIZE9_000762"
     CDS             2460..3401
                     /gene="opp3b"
                     /locus_tag="ACIZE9_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HGC6092646.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3402..4445
                     /locus_tag="ACIZE9_000763"
     CDS             3402..4445
                     /locus_tag="ACIZE9_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092647.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4451..5521
                     /locus_tag="ACIZE9_000764"
     CDS             4451..5521
                     /locus_tag="ACIZE9_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092648.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5511..6464
                     /locus_tag="ACIZE9_000765"
     CDS             5511..6464
                     /locus_tag="ACIZE9_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092649.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6476..7486
                     /locus_tag="ACIZE9_000766"
     CDS             6476..7486
                     /locus_tag="ACIZE9_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HGC6092650.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7771..8592)
                     /locus_tag="ACIZE9_000767"
     CDS             complement(7771..8592)
                     /locus_tag="ACIZE9_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGC6092651.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8689..8967)
                     /locus_tag="ACIZE9_000768"
     CDS             complement(8689..8967)
                     /locus_tag="ACIZE9_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092652.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9235..11244
                     /gene="metG"
                     /locus_tag="ACIZE9_000769"
     CDS             9235..11244
                     /gene="metG"
                     /locus_tag="ACIZE9_000769"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGC6092653.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11723..12310)
                     /locus_tag="ACIZE9_000770"
     CDS             complement(11723..12310)
                     /locus_tag="ACIZE9_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092654.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12485..13807
                     /locus_tag="ACIZE9_000771"
     CDS             12485..13807
                     /locus_tag="ACIZE9_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGC6092655.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13962..14738
                     /locus_tag="ACIZE9_000772"
     CDS             13962..14738
                     /locus_tag="ACIZE9_000772"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGC6092656.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14731..15300
                     /gene="rnmV"
                     /locus_tag="ACIZE9_000773"
     CDS             14731..15300
                     /gene="rnmV"
                     /locus_tag="ACIZE9_000773"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGC6092657.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15293..16177
                     /gene="rsmA"
                     /locus_tag="ACIZE9_000774"
     CDS             15293..16177
                     /gene="rsmA"
                     /locus_tag="ACIZE9_000774"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGC6092658.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16628..17257
                     /locus_tag="ACIZE9_000775"
     CDS             16628..17257
                     /locus_tag="ACIZE9_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092659.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17381..18490)
                     /locus_tag="ACIZE9_000776"
     CDS             complement(17381..18490)
                     /locus_tag="ACIZE9_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092660.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18699..19121
                     /gene="mgsA"
                     /locus_tag="ACIZE9_000777"
     CDS             18699..19121
                     /gene="mgsA"
                     /locus_tag="ACIZE9_000777"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HGC6092661.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      19308..19406
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            19444..19980
                     /locus_tag="ACIZE9_000778"
     CDS             19444..19980
                     /locus_tag="ACIZE9_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HGC6092662.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20020..21783)
                     /locus_tag="ACIZE9_000779"
     CDS             complement(20020..21783)
                     /locus_tag="ACIZE9_000779"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092663.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21786..23501)
                     /locus_tag="ACIZE9_000780"
     CDS             complement(21786..23501)
                     /locus_tag="ACIZE9_000780"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092664.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24280..24504)
                     /locus_tag="ACIZE9_000781"
     CDS             complement(24280..24504)
                     /locus_tag="ACIZE9_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092665.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24695..27472
                     /locus_tag="ACIZE9_000782"
     CDS             24695..27472
                     /locus_tag="ACIZE9_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC6092666.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            27553..27972
                     /locus_tag="ACIZE9_000783"
     CDS             27553..27972
                     /locus_tag="ACIZE9_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6092667.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            27984..28454
                     /locus_tag="ACIZE9_000784"
     CDS             27984..28454
                     /locus_tag="ACIZE9_000784"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6092668.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28471..29250
                     /locus_tag="ACIZE9_000785"
     CDS             28471..29250
                     /locus_tag="ACIZE9_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGC6092669.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29237..30058
                     /locus_tag="ACIZE9_000786"
     CDS             29237..30058
                     /locus_tag="ACIZE9_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC6092670.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            30075..31124
                     /locus_tag="ACIZE9_000787"
     CDS             30075..31124
                     /locus_tag="ACIZE9_000787"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGC6092671.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            31137..32141
                     /locus_tag="ACIZE9_000788"
     CDS             31137..32141
                     /locus_tag="ACIZE9_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGC6092672.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32774..33793
                     /locus_tag="ACIZE9_000789"
     CDS             32774..33793
                     /locus_tag="ACIZE9_000789"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGC6092673.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            33836..34717
                     /gene="galU"
                     /locus_tag="ACIZE9_000790"
     CDS             33836..34717
                     /gene="galU"
                     /locus_tag="ACIZE9_000790"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGC6092674.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            35017..35394
                     /locus_tag="ACIZE9_000791"
     CDS             35017..35394
                     /locus_tag="ACIZE9_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092675.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            36000..36614
                     /locus_tag="ACIZE9_000792"
     CDS             36000..36614
                     /locus_tag="ACIZE9_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGC6092676.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            37387..39126
                     /gene="yfcC"
                     /locus_tag="ACIZE9_000793"
     CDS             37387..39126
                     /gene="yfcC"
                     /locus_tag="ACIZE9_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HGC6092677.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            39283..40467
                     /gene="iadA"
                     /locus_tag="ACIZE9_000794"
     CDS             39283..40467
                     /gene="iadA"
                     /locus_tag="ACIZE9_000794"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HGC6092678.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            40578..40781
                     /locus_tag="ACIZE9_000795"
     CDS             40578..40781
                     /locus_tag="ACIZE9_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGC6092679.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(40882..41544)
                     /locus_tag="ACIZE9_000796"
     CDS             complement(40882..41544)
                     /locus_tag="ACIZE9_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092680.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(41557..43059)
                     /locus_tag="ACIZE9_000797"
     CDS             complement(41557..43059)
                     /locus_tag="ACIZE9_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092681.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            43607..45286
                     /locus_tag="ACIZE9_000798"
     CDS             43607..45286
                     /locus_tag="ACIZE9_000798"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGC6092682.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            45413..45892
                     /locus_tag="ACIZE9_000799"
     CDS             45413..45892
                     /locus_tag="ACIZE9_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGC6092683.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            46111..46791
                     /locus_tag="ACIZE9_000800"
     CDS             46111..46791
                     /locus_tag="ACIZE9_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HGC6092684.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            46799..48130
                     /locus_tag="ACIZE9_000801"
     CDS             46799..48130
                     /locus_tag="ACIZE9_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HGC6092685.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            48145..49107
                     /locus_tag="ACIZE9_000802"
     CDS             48145..49107
                     /locus_tag="ACIZE9_000802"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGC6092686.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            49218..49556
                     /locus_tag="ACIZE9_000803"
     CDS             49218..49556
                     /locus_tag="ACIZE9_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGC6092687.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            49635..50342
                     /locus_tag="ACIZE9_000804"
     CDS             49635..50342
                     /locus_tag="ACIZE9_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HGC6092688.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(50445..51926)
                     /locus_tag="ACIZE9_000805"
     CDS             complement(50445..51926)
                     /locus_tag="ACIZE9_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092689.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            52235..52771
                     /locus_tag="ACIZE9_000806"
     CDS             52235..52771
                     /locus_tag="ACIZE9_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6092690.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            52849..54219
                     /locus_tag="ACIZE9_000807"
     CDS             52849..54219
                     /locus_tag="ACIZE9_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGC6092691.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            54286..54621
                     /locus_tag="ACIZE9_000808"
     CDS             54286..54621
                     /locus_tag="ACIZE9_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092692.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(54702..55559)
                     /locus_tag="ACIZE9_000809"
     CDS             complement(54702..55559)
                     /locus_tag="ACIZE9_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092693.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            55665..56180
                     /gene="tadA"
                     /locus_tag="ACIZE9_000810"
     CDS             55665..56180
                     /gene="tadA"
                     /locus_tag="ACIZE9_000810"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGC6092694.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            56203..56287
                     /gene="ffs"
                     /locus_tag="ACIZE9_000811"
     ncRNA           56203..56287
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACIZE9_000811"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            56497..57882
                     /locus_tag="ACIZE9_000812"
     CDS             56497..57882
                     /locus_tag="ACIZE9_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HGC6092695.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSCLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            57919..58596
                     /locus_tag="ACIZE9_000813"
     CDS             57919..58596
                     /locus_tag="ACIZE9_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGC6092696.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            58604..59368
                     /locus_tag="ACIZE9_000814"
     CDS             58604..59368
                     /locus_tag="ACIZE9_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGC6092697.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            59370..60029
                     /locus_tag="ACIZE9_000815"
     CDS             59370..60029
                     /locus_tag="ACIZE9_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGC6092698.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(60059..60568)
                     /locus_tag="ACIZE9_000816"
     CDS             complement(60059..60568)
                     /locus_tag="ACIZE9_000816"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HGC6092699.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(60680..61678)
                     /locus_tag="ACIZE9_000817"
     CDS             complement(60680..61678)
                     /locus_tag="ACIZE9_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGC6092700.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            61879..62463
                     /locus_tag="ACIZE9_000818"
     CDS             61879..62463
                     /locus_tag="ACIZE9_000818"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC6092701.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(62540..63715)
                     /locus_tag="ACIZE9_000819"
     CDS             complement(62540..63715)
                     /locus_tag="ACIZE9_000819"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGC6092702.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            63797..64177
                     /locus_tag="ACIZE9_000820"
     CDS             63797..64177
                     /locus_tag="ACIZE9_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HGC6092703.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            64251..64613
                     /locus_tag="ACIZE9_000821"
     CDS             64251..64613
                     /locus_tag="ACIZE9_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092704.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT        21255 a        11197 c        13389 g        19179 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctgctgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgtggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt tttcatttga ttgctccttt atttttggtt
     2401 cattatctaa taatgtagcg aaacatctgt cagaagtcaa aagctagggg gaaacattag
     2461 tgaatagtta tatcaaatat gtattaaaac gtgtcttttt catgatcatc acgctttggt
     2521 taattgcaac aatcaccttt ttcttgatgc aattgctgcc gggcacgcca tatacgaatc
     2581 aggaacgttt gagtcctgaa acaatcgaga tgctaaataa acaagtcggt ttggataaac
     2641 cagttatcgt acaatatggg atttatcttt ctaatttgct tcaaggagat tttggaattt
     2701 ccttccaatt taaaaaccag ccagtcgcac atttgttagc tggaagaatc ggaccatcct
     2761 tgcagttagg gttacaggca attatctttg gaacagtcct agggacgatt ttaggaacga
     2821 tctctgccat gaagcaaaat acatgggcag atacatcttc tacactcgta gcgatattag
     2881 gtcgttccat tccaaacttt gtatttgctg ttttattaca atatatcttt gcaatcaaat
     2941 tacaagtttt gccaatcgca aaatgggatg gctttgtgta cacaatctta ccaacaattg
     3001 cgttggccat gtcgccgctt gctgactctg ctcggtttat ccgtacggaa atggtggaag
     3061 tactgcatag tgattatgtg gaattagcaa aagcaaaagg attgagccgt tgggaaatcg
     3121 cctttaaaca tggtcttcga aatagtttga ttccattgat gactttatta ggaccgttag
     3181 ctgtagcatt gatgaccgga tcactggtgg tagaaaatat ctttgctatt cctggtatcg
     3241 gggaacaatt cgttaagtca atcacaacaa atgattatcc tacgatcatg gctgtaacga
     3301 tcctttactc atttatgctg atttttgtta ttttgatcgt ggatctattg tacggtctag
     3361 ttgatccaag aattcgtgtt tcagaaggga gccgaggata aatggaaatg ataccaaagc
     3421 gttatgaaac agttgcagat atccctgcgg atgaatttct tccattacaa aaaaataccg
     3481 aagaagaacg tgaacagatt actgcacctt ctttgaattt tatccaagat tcatggcgcc
     3541 gtttaaagaa aaacaaagct gccgttattt caatggtttt actattggtc atcattttga
     3601 tctctgtgat cacaatcttt gtttctcctc atgatccaac tgcccaaaac gtggcttata
     3661 tcaatttgcc tcctcgtatt ccgggaatca atatcgatgg attgaatgga aaagcaatgg
     3721 ttggtggtga acttgttgat aaatatgctc aagcaaacgt cccttcaaac gtaaatttct
     3781 ttttaggaac agacggtttg ggacgtgatg tattaagccg cttatttatg ggaatgagaa
     3841 tctcgttgct gatcgcattt attgctgcat tactagatgt aacgattggt gtagcttacg
     3901 ggttggtttc tggtttgtta ggcggacgtg tcgataacgt gatgcaacgt tttttggaaa
     3961 tcttatcagg aattccaaac ctcgttgtca tgattttgat gttggtcgtt tttgaaccag
     4021 gaattttttc aatcgtggct gctatggcca tcacaaactg gataccaatg gcacgtatcg
     4081 ttcgtgcaca aacaatgaaa ttaaaagatc aagaatatgt tttagctgga ttgacattag
     4141 gtgaatcaag aatgaaaatt gcattcaaac atattttgcc gaatatctct agtgtcatta
     4201 ttattcaaat gatgtttagt attccatctg ctattttctt cgaagccttt ttaagcttta
     4261 tcggtttagg tcttacgcct ccgtcagctt cattaggaac gatgttgagc gaagggtaca
     4321 agacattcct gtatctgcct tatctattat ggattccggc agtaacttta tcggttatca
     4381 tgattggctt taacttactt gctgatggat tgcgtgatgc ctttgatcct aaaatgaaag
     4441 agtgaagacg atgacgaaaa ttttagaagt gaaagactta gaaatctctt ttgatacgta
     4501 tgctggaaag gtacgagcga ttcgcggtgt caattttcat ttgaataaag gagaaacatt
     4561 ggcgatcgtt ggggaatctg gaagtggaaa atcagtgacg accagaagca tcatgcgctt
     4621 gctgtcaagc aacgccaata tagatgctgg tcaaatcctc tttaaaggta acgatatcgt
     4681 tggaaaatca gaaagagaga tgcaaaaaat ccgtggtaaa gaaatagcga tgattttcca
     4741 agatccaatg acctctttag atccgacgat gcccattggg aagcaagtcg ctgagtccct
     4801 tagaaagcat aataaagttt caaaaaaaga gggacaaaaa gctgcattag aattgcttaa
     4861 attagttgga atacccgaag ctgagaaacg tatcaacagt tatccgcatc agttctcagg
     4921 aggtcagcgt caacggatcg tgatcgcgat tgcactggta tgttatccgg aaatcctgat
     4981 tgctgatgaa cctacaacag cgcttgatgt gactattcaa gcacagattt tggagctgct
     5041 gaaagaaatt cagacaaaaa tcgatacatc aattatcttt atcactcatg accttggtgt
     5101 agtagcgaat gtcgctgatc gtgtcgctgt catgtatgga ggaagaatcg ttgaagttgg
     5161 aacatcggaa gaaattttct acaacccgca acatccctat acttggggac tgcttggttc
     5221 aatgccgaca ttagatagtg cgaacgatcg attgtatgct attcctggtt ctccaccgga
     5281 tttattgaac ccgccaaaag gagacgcatt ctatccaaga aatgaattcg cgatgaaaat
     5341 cgatgcagaa caagaaccac cattttttga actatcaaaa acacacaagg cagcaacttg
     5401 gctacttgct ccgcaggcac ccaaagtgac accgccagaa gaaatccaac gtcgctgggc
     5461 tatctttaaa gagaaacaaa aacatactta cggtcaagga ggaattgctg atgccaaata
     5521 aactacttga agttaaagga ttgaaacagt atttcaatgt aggaaaaaag aatgaagtac
     5581 atgctgtaaa tgacatcagc tttcacattt atgaaggaga aacattcggt ttagttggag
     5641 aatctggaag cggaaaatcc actactggcc gtacgatcat tcgcttgaat gaacctactg
     5701 atggtgagat attattcgac ggtcaagata taacgaagat caaagataaa aaaggtttga
     5761 cgaaattccg gcatgatgtt cagatgatct ttcaagatcc atacgcttcg ttgaatcctc
     5821 gtatgaaagt cagagatatc attgccgaag gaattgatgt taatggacta gctaaatcat
     5881 ctgaagagcg tgcaaaaaaa gtcgatgatc tattgagaac tgttggattg aatccaagcc
     5941 acggtactcg ttatcctcat gaattttcag gtgggcaacg ccagcgtatt ggtattgcac
     6001 gagcattggc agtaaaaccg cgttttatca tttgtgatga accaatttct gcactagatg
     6061 tgtcgatcca agcccaagtg gtcaatttgt tgcaagatct ccaaaaagaa catcaattga
     6121 cctatctatt tattgcacat gatttgtcga tggttaaaca tattagtgac cgaatcggtg
     6181 taatgcataa cggcttgtta ttagagatgg gaacaagtga tgaaatctat aatcacggtg
     6241 ttcatcctta tacagaaagt ttgttatctg ctattcctct accagatcca gaccatgaga
     6301 gaaaacgcag aagaatcaaa tatcaacctg aaccagatga cggacaagta cgtcaacttc
     6361 gtgaaatcgc accagaacat tttgtctatg caactgagca ggaagtccca tattacgcaa
     6421 aaaaactaaa acgacaaaag gaatctcttc tggttgctaa ctaggaggga catagatgct
     6481 aaaagctttt aaattccgta tgtatccgac agaagaacaa aaacagcaat tgattcgtac
     6541 ttttggatgt gctcgattta cctataacca tttgctgaaa aagcggcaga aaagttggca
     6601 acaaacagga gtagccaatt tttcgctcac acccgctaca ttaaaaaaag aatacccatt
     6661 cttaaaagaa gtagacagtc ttgctttagc aaatgcacag cttaatttgg atcgggcttt
     6721 tcgcaattat ttcaagggac gtgccagctt cccaaagctt aaaacgaaaa aaagtatgtg
     6781 gcaatcttat acgaccaaca accaaacccg tacgatctat ctggaaaatg gctacttaaa
     6841 gttaccaaaa caaaaagaac taatcaagat aaatcagcat cggccagttg aaggatcgat
     6901 tcgctccgct acgatttctg ctcgatataa tgaagaattt tatgtcgcac tactttgtga
     6961 tgtttcgcca gtaaaaaaag aatctttagc taaatggatc gggatcgcct atcatccgaa
     7021 gacattgatc caaacatctc gacctctaga agtaacttta ccaaaatttc accagacaga
     7081 agaaaagctg caacatgcac agcggaaatt gaatgtgaaa gtccgctccg ctcaccatag
     7141 aaagatcagg ttagatcagg caagcaatta tcagaaacaa aagagaaaag taatggatct
     7201 ttatctgaaa caaaagaacc agcgagaaga ttatcttgaa caattatctg ggaaattggt
     7261 caaacaatat gactacttat ttgtagaatc ttttccaaaa gaagaggcac atgctgattt
     7321 ttctattcac gactggcata aattaataac aaaattgcgt tataagtccc aatggtataa
     7381 taaaaaattt cttttgatca ataccgacgg agcagaagaa agcaattccg taagaaagag
     7441 ccaagtagta gaaaaaatgg gcagacattc ggttatcaag ggataaaaaa tgaatgaaac
     7501 tgataggagc gttagggtta gccttgttaa taaaaagtct taatgacttt tgtttctagg
     7561 aatttttctt ttgaagaaaa gctcactaat tatgacaaac caataaaaca atagcagaaa
     7621 aagttcgtac gagctttttc tgctattgtt aattttttat tcagaaagtt tacgaataca
     7681 tcaaaattct gaaacaaaaa acgtaactca caaagagttg tttttgcgtt ttttcttgaa
     7741 tgattaggtc tgaatctttt gctcacaacc ttattcatgg tgccccggct tgagctgata
     7801 gatttttgaa ggacggccga ttcctacagg acgttcaccg atctcatcga aatattggag
     7861 catagctttc ttaaaattgg aatgatcgat cgttttataa tcgatcccta agaatttagc
     7921 aaatactttt cgagcttccg taatcgtgaa atctttacct aaaacttgta gaacttgcgg
     7981 ctcgtgttcc attttattga ctacacggtt gaatgctttc aagatgattt gactatggtc
     8041 aaaagccaaa gtatctttgc cagaagactc tccagtgact aaatcaagcg agatagccac
     8101 ttctccgcta gataaatgga tcttgttact atgacgttct agtgtgaacc agcgtacttc
     8161 cttggcatca tctccggcga ttagcggttc ttctccaata aaggctaagt agctgactgt
     8221 gacgacccag cctcgcggat ctcgattagg cgtactgaat gtatgcagtt gctcaatatt
     8281 ttcttttgaa ataaccacac cagtttcttc ctttgtttct cttaagacgc tttctccagt
     8341 tgactcatcc ttttggacaa agccaccagg caatgcccat gaatttcgat aaggatgccc
     8401 ttttctttgg atcaacaaaa ctttcagctg atcttcttct ttgttatagc acatcagtac
     8461 gatatcgaca gtcaaagagg gcttgtcata ttctggacgt tcctgttttt gataccagtt
     8521 aagaaattct tcttcacttg ctttatgttc ataatataat ttttcttctt ctttagaagc
     8581 aaaacggttc atctgaccac ctccattgac agtaaaagta ctttttacct tattgtagca
     8641 gactctgaaa aaaaaccaag gatttacttg aaaaatctag gttatcattt aaatatgaaa
     8701 aataaatgga agtatgagat tgaataaaaa gaaaagcaga taaaacggca atactttata
     8761 ccgctcttca cgaatggcaa agaagccaca aataacgata tatacgtcaa tgataaaacg
     8821 caaaatccaa gctgctgtca taaaactgtt caaatgccca tggaggttaa aataaccata
     8881 catacgaata taaaaatagc tgaatattaa atgtgctaat gaaagaaaag caatactaag
     8941 tgtaaaaaaa agatgtttct tctgcatgat tgttccagtc ccttactaag atagatagtc
     9001 tttattatac cacgtgtgag gggagaaata aaaagccgtt ttttagtaga tatgaaacaa
     9061 aacaaaaacc cgcatttatt caacctattc atccttttaa aggatagatt gaacgtagat
     9121 agaagtcgtt tatccagtct ttttcatttt gaaaaaaagc taacagcatg ctttttttat
     9181 ggtatactag caaggaaacg aattcgcatc atgcgataaa ggaggaagag ccccgtggca
     9241 gaaaaggaaa ctttttatat cactacgcca atctattatc caagcggcaa acttcatatc
     9301 ggcaactcgt atactacgat tgcatgtgac gcaattgctc gttataaacg gttgatgggc
     9361 tttgatgtgt tttatctcac tggagtggat gaacatggtc aaaaaatcga aacaaaagca
     9421 gaagaactag gtgtaaaacc gcaagaatat gtagataaaa tggcggctga tgtcaagaaa
     9481 ttatggaaaa cgcttgatat cagttatgat aaattcattc gcacgacaga tgattaccat
     9541 aaagcagctg ttcaaaaaat atttgatcgt ttattagaac agggagatat ttacttaggt
     9601 gaatatgaag gctggtactc tgtttctgac gaagaattct ttacagaaac acaacttgca
     9661 gaagtgtaca aagatgacga aggtaacgtg atcggtggta aagcgccaag tggacacgaa
     9721 gtagaattgg taaaagaaga atcatacttc ttccgcatga gcaaatacgc agaccgtcta
     9781 ttggaatact atgaagaaca tcccgaattc atccagccag aatctcgtaa aaacgaaatg
     9841 atcaacaact ttatcaaacc aggattagag gatcttgcag tttcacgaac aacttttact
     9901 tggggagtac cagtcaagag tgatccgaaa catgtggtgt atgtatggat cgatgcatta
     9961 tccaattata ttactgcact aggatatggc tccgaagatg aaagtctatt cgaaaaatac
    10021 tggcctgcag atgttcagat ggtcggtaaa gaaatcgttc gctttcatac gatctattgg
    10081 ccaatcatgc tgatggccct tgatttgcct ctacctaaaa aagtatttgg gcatggctgg
    10141 ctattgatga aagacggaaa aatgtctaaa tcaaaaggaa atgtcgttta tcctgaaatg
    10201 cttgtggaac gttatggttt agatgcactc cgttattatt tgcttcgtgc tgttccgttt
    10261 gggtcagatg gtgtctttac gccagaagat tttgtttccc gtgtcaatta tgatctggca
    10321 aatgatctag ggaacttatt gaatcgaacg attgctatga tcaacaaata ttgtgatgga
    10381 ctcgttcctg actatgcctc acttgtcact ccatttgata gtgaactgtc tacgacggct
    10441 gctaacgttg tcggacgtta ccatgatgca atggaaaaaa tggaattcaa tacagcattg
    10501 gctgaaatct gggtgctgat ttctcgtgca aacaaataca ttgatgaaac agaaccatgg
    10561 gtattagcaa aagacgaaga aaagaaagct gaattgaata gtgtcatgat ccatttagct
    10621 gaatctttgc gtatcgcagc gatattactt cagccaatca tgacagaaac gccagagaag
    10681 atcttcaatc aactaggatt ggactctgaa acaatgaatc ttgaaggatt acactttggc
    10741 gaatttcctt caggaacaaa agtagttgca aaaggtacac caatcttccc acgtttagat
    10801 atggaagaag aagttgcttt tattcaagaa aaaatgtctg aaggtactca aacaaacgaa
    10861 gatacagtca aatgggatcc agaagaaaca gaacttgttt caacgaaaga aaaacaaatc
    10921 aaatttgatg tatttgaaaa agtagaacta aaagtagcag aagtcatcaa ctgtcaaaaa
    10981 gtagaagggg cagataagtt gctgcaattc cgactagatg ctggagacag ccaagaccgt
    11041 caaatcttgt caggaatcgc tgaattttat cctgatccaa gcgaattgat cgggaaaaaa
    11101 gtcgtcattg tagcaaatct gaaaccacga aagatgcgtg gacaaatcag tcaaggaatg
    11161 atcctttctg cagaagcacc agatggctct ttacaagtaa tcgaagcacc aaaatccatg
    11221 ccaaatggct cagaaatcgc atagaaattc aaagggggta tgacactagt tgtgtcatac
    11281 cccctttttc cgaaatttga gaagcaattt tcgtaaattc cttcttatta cttgaagcca
    11341 atcatataat acagaaacag agaactatcc aaaataaatc ctagaaaaag aagtacgagc
    11401 ttcgctgatt tttgttaatt tagaataata ctaataggaa tcgtaaaaac agaaaaaaag
    11461 cataatgata aagggtcggg cagattttaa ttgattcatc tggtactctt ttttattgtc
    11521 cttacattca taaagtttga atgcaatgac tttattacat ctatatttat atctaacagt
    11581 agcgttgatg tgttaattat aagttctatc actttatgtt caattagttt gtgctcttat
    11641 atgtgtgatt gaaaatatag ataaaaaaac aatcatcggc tttgacttcg atgattgttt
    11701 tctttatttt gtaaaaatcc tatcacttga ttttatggta accttttatt tttgtcttca
    11761 aacggcttgg taagagagca gtaagcagtg caaatgggat cgaaaagaca taccagaaaa
    11821 tcgtacgtcc gataccataa tgttgataga gctttgtcaa catcacgtgt aacaagatca
    11881 accctaaaag caaggagcca gctataaacc aatgattatc ccaatgcatg acttcactaa
    11941 gtgccatcac tccaaaagga tagaaataaa aatagatccc gactaaggtc atccgccagt
    12001 tctttgtaaa tgttccgata ttcaataaaa agaaaatcgc tgaaagcaaa ataccgatag
    12061 gcggaaaaag cccaaccaaa aaggaataca acatccccca caagatcatc acaggacctt
    12121 tgatcaatgc aacgattgcg atgaacaaag tcagcaatat tagtttttgt gataacgttg
    12181 caacagtcat taatccaaat aaaattaatg tgaaccaatg ccaatgggac tgctgttgtt
    12241 ctttacggga aaaatcgacc cggttggata aataatctgc taatttcgga taagaacgct
    12301 taaaatccat aaactgttcc tccttcgtgg aaaaggtagg tttagtatac gaaaaataaa
    12361 aaagaaatac atccgtctta agagggagtt tttcactgaa agtggagaaa aaagaatggt
    12421 aaattaaaat attctcagtt atactgaaaa ttataccaaa tttcaaagaa gaaagaggat
    12481 gggaatgaaa ggcaaactaa aacgagaaat caatctgttt ggcgcattag ctaccgttat
    12541 gggaaccgtg atcggtgcag gcgtcttctt caaaactgct gctgttactg ctagtactca
    12601 gtctacaagt ttgacattgc tagcttggct tttgggtggt ttcttaacga tctgtgctgg
    12661 attgacagtg gctgaattag ctacagcaat cccggaaact ggtggagctg taaaatatat
    12721 tgaagctgcg tatggaaaat tgcccagctt tttattagga tgggcgcaaa gcttgattta
    12781 ctttcctgct aatattgctg cattatcgat tatctttgcg acacaattga cgaacttatt
    12841 acaattatct accgattatc ttttgttgat tgcagtgatc accgctgttt ctgtgacagg
    12901 gttgaatttg ttagggacaa aagtcggtgc ttctgtacaa tcagtgacgt tgattgttaa
    12961 attaatacca attgctgtga ttgtcatatg gggattattg accccaggac aaggaactgt
    13021 ccagttattt ccaatcgaag ctggaaaaga tgttactttt gtcgaaggat tgagcagtgc
    13081 gttgttagca acgttgtttg cttatgacgg ctggttaggt gtcggtgcaa tggcagggga
    13141 aatgaaacgg ccggaaaaag atttgcctaa agcaattatt cttggtttga gttttgtaac
    13201 agtcgtttat ctattgatca attttgtttt tttgaaaact ttgccgattg atcatcttgc
    13261 cggtaatttg aatgcagctt ctgaagcatc agacgtcatt tttggaggaa tcggtggaaa
    13321 gctggtcact attgggatct tgatctcggt atacggtgca ttgaacggtt atacactaac
    13381 tgggatccgc gtgccttatg cgatggcttt agaagacgag ctacctttca gtaaacagct
    13441 gacaaagctt tcaaagaagt ttacggttcc ttatgttcct gcggttttcc agttagcagt
    13501 agcttgtatt atgatgagcc ttggttcttt cgacttttta acagacatgt tgatttttgt
    13561 gatgtggcta ttcagtttac tgatttttat cggtgtcttt attttaagaa aaaaagcgcc
    13621 ggaattgcca cgtccatata aagtaccact ttatccaatc gttccgatta ttgcgattct
    13681 cggtgctatt ttcattttag gtatgacgat gatgacgcaa acgaaattag cattgatcgg
    13741 tataggtgtt accttgatag gtatcccagt ctattatcaa aaaaagaaaa aacgctcaga
    13801 agagtaaaat atttcaacaa cagacagaaa aagtacgaac taggtcctct agatcttcgt
    13861 gctttttcta tttcaataaa acaagttctt ctattttgat ttttgctact tctgcaagta
    13921 gtgcttatgt gctaaagtaa gaatgaaaag gagagataaa catgatattt gattctcata
    13981 cccatttaaa tgctgaacag ttcaatgaag atattccaga aacgattcag cgagcacaag
    14041 aaatgggggt aacgaaaatg gcggtcgtgg gcttcgatac gccaacgatt gaaaagtctt
    14101 tgcaattaag ccatgactat ccaaatatat acagtattat cggctggcat ccgacagagg
    14161 ctggcagtta tacgaaagaa atcgaaaata aattacaaga acaattgact ttaccaaagg
    14221 ttgtagcatt aggggaaatt ggcttggatt atcattggat ggaagacccg aaagaagtcc
    14281 aagataaagt atttcgcaga cagattgcta tcgcaaaaga aatgaaccta ccaatcagta
    14341 ttcatactag agaagcactt gaagacacgt atcaaatcct aaaagaagaa gatgttcgag
    14401 atatcggtgg aatcatgcat agtttcagtg gtgattatga atgggcaaaa cgatttcttg
    14461 acttagggat gcatatttca tttagcggtg tcgtcacttt caaaaaagca ttagacgtcc
    14521 aagaggctgc agcaaatgta ccaatcgaac gattacttgt ggaaacagat gccccttatc
    14581 tggcaccagt tccttttaga ggaaagcgaa atgaaccagg ctatactcgt tatacagtag
    14641 aaaagattgc tgaacttcgg aatcttccga cagaagaagt ggctgcccaa acatggacaa
    14701 atgcgcaccg attatttggt ctaagcgaac atggataaga tgaagatcca agagattata
    14761 gtcgttgaag gaaaagacga tacaagaagg ctgcgggaag tagttgatgc agatacgata
    14821 gaaacaatag ggtctgcaat caatgaagag atcctgatgc aaattgaaca tgcccaagag
    14881 actcgtggag tgatcgtttt taccgatcct gatttttcag gagaaaaaat aagaaaaatc
    14941 attatggaag ctgttcctca ggcaaaacat gcttttttgc cgcgcacaca agctaaacca
    15001 aagaaaaagg gaagccttgg tgtcgagcat gcaagtgatg ctgctatttt agaagcattg
    15061 aaaaaggtcg tgacgccaga catttcccaa acggctgttt ctgaaatcac tagacaagac
    15121 cttttagact atggtttaat agctggggca caagcaaaag aaaaacgaga aaaactaggt
    15181 gacgagttgc gcatcggtta cacgaacggc aaacaattgg aaaaacgttt gaagatgttt
    15241 cgtattacgc cgaaagaact cgcccaagca atgaaaatag tggaggaaca acatgagtga
    15301 atatcgtgaa attgcgacac cctctagaac aaaagagatt ttattgaaac atggtttttc
    15361 atttaaaaaa agtttaggac aaaattttct gactgaacca aatattttaa ggaaaatcgt
    15421 agaaactgcg caaatagatg aacatacgaa cgtgatcgaa gttggaccag gaatcggtgc
    15481 attgacggaa caattagcca agcatgcaaa acaagtcgta gcatttgaga tcgatgatcg
    15541 tttgatccct gtattggctg atacgatgca accctatgac aatgtgacta ttgtacatca
    15601 agatatttta aagaccgatt tgtcaacagc tgttagagaa acatttcatg aggagcttcc
    15661 gttaaaagtc gtagcgaatt taccttacta tattacgaca ccgatcatga tgcattttct
    15721 tgaatcagat ttggttgtgg atgaactagt cgtcatgatg caaaaagaag tagctgatcg
    15781 tatctctgct gaaccaggaa cgaaagctta tggttcatta tcgattgctg ttcaatatta
    15841 tatggaagcc agtttagcat tcatcgtacc aaaaacagta tttgtccctc agccaaatgt
    15901 agattcagcg attttgaaac tgacaagaag agatataccg gcagtcgaag tgacagacga
    15961 aaaagcattt ttccgattga caaaagcggc atttcagcaa agaagaaaaa cgctttggaa
    16021 taacttgcag cattcgtatg gcaaagatga ccagacaaaa gcatggttag caaaaagctt
    16081 ggaaacagct ggaatcgatc caaaacgtcg tggggagact ttgtcattac aagaattcgc
    16141 cgcattaagc aatgcgatgt cagaaaatat gcagtaaaaa aagaggttgt gacagaagtt
    16201 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa acaaaaatag ttcctcatgt
    16261 ttttcgtttg tttgggctta ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga
    16321 ggttgtgggc ctgccgttta actctaagtc acaaggaaca atttcaaaaa acagcttctc
    16381 atgtttttga gttagttggt cttattactt gatgcaagct tttgaccact attatgccga
    16441 acaaggagat gtgacacaaa ttttgtcaca tctcctattt ttgtttcttg atcaaaaaat
    16501 tcttatactt gatactcaca ctcattttgt atggatttag aaaagaatat gtgtcttgac
    16561 agttattagt aagtgagtta tactaagtcg acatttatgt gtcaagacat attaggagag
    16621 agaaaaaatg agaaaaaatt cagttcgaaa actaacgatt tctgctttat tgattgggat
    16681 gggggtcatt atcccaatgg tcatgcctaa aatcatgatt ccaccagctt cctttacttt
    16741 ggcgtctcat gtgccattat ttattgcgat gttttttaca ccaggagttg cagtggctgt
    16801 tgcgctaggt acgacatttg gtttcttttt aacaacgccg gttatcatcg cattgcgagc
    16861 attgtcacat cttgtgtttg cgttgattgg ggcttggtac ttgcaaaagc atccgagtat
    16921 cgttttaaaa aatggacagt ttacttttgc taattggcgt ttccaagggt tcaattttgt
    16981 gatcggtgtg attcattctt tagcagaaat gctagtagtc agcatctttt actttattgg
    17041 taatatgcct gaaacatatt attctcaagg atatttttat acagtattca tcttgatggg
    17101 gattggtggg cttatccaca gtttagttga ttataatatt gcttatttta tagcaggaac
    17161 actcagcaaa tattttgata tccccgtatt tacggcagca aaaaaagaaa atcggaaaga
    17221 gtcgattcaa gggtacgcga agaaaacgac atattagaca tgatctctca aaaaaaaaac
    17281 tctcatctag taatggataa taaatcctct aagatgagag ttttttgtcc taaaaagagc
    17341 tgcaccaaca tcttctggca cagctctaac agggggcaat ttatggaagt ttgatgactt
    17401 gttctgtttc tttatcaaag aagtggcctt tgctgatgtt gaaggcaagg tcgactattt
    17461 cgcctggttt atggaaatct cttgcatcta cttttgagat gaactcagta gaaccagttt
    17521 ttgtgtaaag catcgtttca gctccaagta attcggaaac gacaacttct gatttcacta
    17581 cggcttcagg tgaagcttca agggctactt gttcactgtg gatgtcttct ggacgaatac
    17641 cgaagataac ttcttttcct tcataacctt tttcaactaa tactttgttt tttccttcag
    17701 gaatacgaag cttaagccca tgtccatctg tgataacacc atttttcaat gtcacattaa
    17761 agaagttcat ggcaggagat ccaataaagc cggcaacgaa catattgacg ggtgtatcat
    17821 aaacttcttt cggtgtaccg atttgttgga taaatccgtc tttcatgata acgattcggt
    17881 cagccatagt cattgcttct gtctgatcgt gagtaacata gatggtcgtt gtttcaagac
    17941 gctggtgaag tttggcaatc tcagcacgca tggctacacg taatttagca tctaaatttg
    18001 ataatggctc atccattaag aagacttttg catcccgaac gattgcccgt cccaatgcca
    18061 cacgttggcg ttgtccacca gataaagcag ctggttttcg tttcaagtat tctgtcagac
    18121 ctaagatctc tgctgcattg tccacacgtt ttttgatgtc tgctttatca tatttacgta
    18181 atttcaagcc aaaagccata ttatcaaaaa cagtcatatg aggatacaat gcgtagtttt
    18241 ggaaaaccat ggcaatatca cggtctttag gtgccacgtc attcatgact tttccgccga
    18301 tatttagttc tccttcagag atatcttcca gtcccgcgat cattcgcaaa gtagttgact
    18361 ttccacaacc ggaaggacca acaaaaacga taaattcacg gtctttgatt gatagattaa
    18421 aatcagttac agaataattt tctgcattgt catatttttt atatacgttt ttcagagcca
    18481 tttctaccat aatacgttcc acactttctt ttttagtttt attaactatt taaagtataa
    18541 atgaaagcgt taactaactt caatgtcatg ttgaacaaga attttttctt ttttttgtca
    18601 atgtgctagt tttaagcttt aataaatatc cataagaaat aaaaactgat acactggagt
    18661 aaataagtat gttaacaata tcaaaaggag tgtctcttat gaaaatcgct ttgatcgctc
    18721 atgaccgaaa aaaacctatg atggtgaaat tagcaacagc gtataaaaca atattggaaa
    18781 aacatgaact ttttgctacc gggacgactg ggcagaggat cacggaagca accggcttgc
    18841 cgatccatcg gtttaaatcc ggaccgttag gcggggatca gcaaattgga gccatgattt
    18901 cggaggatca gttagatttg gtgatttttc ttcgagaccc gctggctgca cagccccatg
    18961 aaccagatgt aacagcactt atccgtttat ctgatgtcta tgagattccg ttagctacga
    19021 atatcggaac agctgaggtg ctactaagag gactggaagc cggcttccta gattttcgaa
    19081 gaatcgtcca tgaaatagac aagcatccac tttcattttg atggataagc gtatggaaaa
    19141 ataacgttta atgttcgcct atatgtagct ataaaagcta aacaaactga taatatgcga
    19201 tataatacga acgtattgga taatataaac aataatatta gtttttcgta tttgcagtaa
    19261 atgtgaaaat atgctatagt ttctgtggga aaagatccca aaaataatac agagtagaaa
    19321 ataaagcgtt aagtgctaag aggatgggat gttgcctctt ggacgaagga cgtaatgttc
    19381 gcggttttat tttcgcattc gctgcatgat acgatgtagc agctcttaaa ggagatgcta
    19441 aaaatgaaga aacaccggtt agacgcacgt atgattgcta ttatgggctt attgattgca
    19501 ttgatggtca ctttgtcccg actggtagca atcgagaccc catttattaa aatcagtgtc
    19561 acatttattc cacaagtgat catgggcatt ctttttggtc ctttttggtc agggataggc
    19621 gcagttttag ctgatttagt aggaatggcc ctcttctcga aatctgcatt ctttattgga
    19681 tttacattga atgcatttat tgaaggagca atctacggat tctttttcta tcgaaaagag
    19741 atcacttgga aaaatgccat tctggctacg cttagtgtca cgctgatcat caacttattt
    19801 ttgacaccat tatggcttgc gttgatgtac catgtgccat tgttcagctg ggtcgtttgg
    19861 gcgccccgcc tgttaaaaac agtaatatgg ttaccgattc aatcaattgc catttattac
    19921 gtaggacgta gtattcctta caaaaaaatt ttaagaagtt tagcgatcca cgctaaataa
    19981 aaaacaagca gtcttcccat cccagaagac tgcttgtttt tattgtgctg tgaattgtgc
    20041 ttgatagagc cgtcggtaat aaccatcttt ttgaagcagc tcatcatggg tgcccatttc
    20101 gacaatagct ccctgatcca tcactaatat ctggtccgca tttttgattg tggacaggcg
    20161 atgggcaatc acaaaactgg tttttccttc catcattgct aagaaggctt gttggatttt
    20221 tttctctgtc aatgtatcga ctgagctggt agcttcatct aagatcaaca tagggggatt
    20281 actgatcatc gttcgagcaa tcgtcaacag ttggcgttgt ccatctgata tctttaaccc
    20341 ttgaccgcca atcttagtat ctaatttttc cggcaaacgt tctacaaatt catacatata
    20401 agaggctttt agggcatcat tgatttctgc gtcacttgct tccggattcc caaaacgaag
    20461 attttctcgc aatgtactgt caaatagcca agtatcttgt aacaccattc caaaactttt
    20521 acgtaatgta tcacgttgga tagagcggat gtcatggtca tcgactgtaa ttgttccttt
    20581 tgttgtgtca taaaaacgca tcagcaaatt aacaagtgtg gattttccgg cccctgtttt
    20641 tcctactata gcaatggttt gacctggata agcagtaaaa ttgaaatctt cgatcaaacg
    20701 ctgcttgggg tcataagaaa aagaaacatg atcaaaagag acttttcctt tgatattttt
    20761 gggttccaag gcataggcat ctggcaaatc aggcttttct tctggctgat cgatcaaatc
    20821 aaatgctcgt tctagaccag aaaaagcggt ttgcagttgt gtcgtgattc cagaaagttc
    20881 gataaatggt ttagaaaact gacttgagta gatcgtaaag ctggaaatca caccaacagt
    20941 gattgacgaa ccactcttca atgccaatag gccgccaact aaaccaatcg ataaataagc
    21001 aaggtgatct acaaaacgag aagacgggtt tgtcaaggaa gaagaaaatt gtgcccgttg
    21061 tcctttttca tatagatcag catttagcag ttcaaattgc tgttgactag cttcttcttg
    21121 ctgaaaagct ttcacgattt tctggttacc gattcgttcg gtcacaaagc ccgagatatc
    21181 cccaataatc ctttgctgtc tatcgaaatt tgtttgtgaa gcacgagcaa cgatccaact
    21241 cacaaggaaa ataattggtg tagaacaaag aacgaccaat gtcagaagtg gacttagacg
    21301 catcataaaa ataaacgaaa gaatgatgat tgccactcca gaaaataatt gattgaaggc
    21361 cgcagaaatt gcaatggaaa tattgtccat atcatttgta aatcgactga cgatatttcc
    21421 gtgggagttt tgatcataat aacgaagtgg caatcgattc agatgagcaa atgcatcttt
    21481 tcttaatttt gcaacggata agtaagctaa ccgattgctt aacacttgga tgagccattg
    21541 actgactacg ttgattaaaa cgataccacc gaatagaata agtaaatgga acagtcgatt
    21601 gaagcggacc tgtccttctc caatcatttg atcgatactt tgaccaattt gtaacgtcat
    21661 cacaactgtt gcaatcccat tgatgattcc tagtatcaca gctagccaaa tgtcttttgc
    21721 ataggcagta aggtaaggaa tgaatcggcg gagcgtctgc aaggataatt tttttacttt
    21781 cataactatt cttcctcctg tgatgcgacg atttcctgat attctgctga ttgagcaagt
    21841 aattcttcat gggtaccctg agcagcaatc ttaccttgat ccatcactaa gatatgatgt
    21901 gcttcttgaa tagagcggac acgttgggag ataataatca ctgtactgcc aagataagtc
    21961 tgtagcgcct tacgcaaatc caagtctgtt tgataatcca acgcacttaa agagtcatct
    22021 aaaatcagta atgctggctt ggcaatcaaa gctcttgcaa tcgtcagtcg ctgtttttgt
    22081 ccgccagaga aatttttccc attttccatg acttttgtat ctaaaccatt tggaagctga
    22141 cggacaaatt cttctgcctg agcgattttc agagcttccc aacattcttt ttctgtggcg
    22201 tctttcttac cccattgaag gttttcacga atagtcccgg taaatagtac agaagtttgg
    22261 ggaacaagag caatttgctg acggagatga tccagctgcc aagaacgaac atccattccg
    22321 tccattataa ctgtaccgga actgacatca tagaaacgcg gaatcaattg tgtcaaagtc
    22381 gttttcccgc ttccggttgg accaatgatt ccaaggactg tatttcgctt cagctgaaat
    22441 gtaatatttt ggagagaaag accagaatca ggagtataac ggaagtcaac atggtcaaaa
    22501 gcgataattg cttcagaaga aaaatcggga gtagtactga cctcagcttc aagaatcgaa
    22561 ttttctgtgt ctagcacctc tttcacccga tttcctgaag cttcggcacg tgtgaagatc
    22621 acgacgaggt ttgaaacaac gatcagtgcc aaaagcattt gattcatata attgatcaaa
    22681 gcaagaactt gtccttgttg caagctacca atatttactt tgatcccgcc aactgtcagc
    22741 aaacagatga tcccgacatt catgatcaag gttgtagcag gtgataatag ggcagagata
    22801 ttggaaacac gtaaataatt gttcgctaga tcatttgtgc ttttatcgaa cttctctgtt
    22861 tctttttttg tctgcgcaaa tgcgcggatg acacgaacac cgctaagatt ctgactaacg
    22921 tgttcattga gctgatctag tttttcttgc actttttggt agagaggaac ggtttttttg
    22981 atgataaaaa ataaaatgat tgagaaaata ggcaataatg ctaagaaaaa cagacctact
    23041 tcccagtcga tcacaaaagc catgaccact gacccgatac ttaaaaacgg tgctctgatc
    23101 aataaacgaa tgaccattgc taaagctagc tgaagctgat tgatgtcgtt tgtcattcgg
    23161 gtgatcaagg tatctgttcc aaaatgattc aactcgttgt gagagaaagt attgattttt
    23221 ttgattagct gattacgtaa ctctgtacca aatccttgtg aagctactga agcatagtat
    23281 tggcaaatga tagcacaaat cagaccaatc acagacatag cgaccatcca taagcccatt
    23341 tcaatgattt ttcctcggtc attcattttt agtccattat cgatcaagga agccatcatt
    23401 aaaggcagga caagttcgaa gacagcttca agaaatttga agaacgggcc caaaatgatt
    23461 tgcttacgat agtcttttgc ataacgtaat aactgaatca tatgattcct cctattattt
    23521 atttgtccac aattgaaaaa acaagtacta ccacattgta gcttaggaaa tttagaatga
    23581 aaagagaaca agccttttca taaatgaaag ttttattatg aagaagcttt agaaattgaa
    23641 tagactattt tttttaaaaa aaagaaaatg agaaaacatg ccagtctctt cattcatagg
    23701 aacgtctatt ttacttaatt tttctataaa tgaattctgc ataaaaaata tatcaagtaa
    23761 atgtttatag atgaaactct atttacttct tttttaattt gttcttgcaa tcttttttgc
    23821 tacgtaattt ttgtaaaaaa gtgggttgag agaaatctaa ttgattttca aagaaggagt
    23881 atgaaaatga gaaaaatatt tattcgttta ttgtgggtac tatcttagag gaataaataa
    23941 tagtggagaa aactatggtt tggcgcagat tctatcaggt ttgatggaac gaagacaacc
    24001 tcccgacatc aagtcaaaag ccacttgaga ttttgatctg aaaataaaaa aagaaaacaa
    24061 ggtaggaaca tcaatgtttc taccttgttt tcgtaatcaa tgggaaaaaa ctaagagtgg
    24121 tgtacgtaat caataaaaag gatggtgaca acagtacctc tttactctct gaaagcatca
    24181 taactcgttt ttcctcatta tgccaataaa ttgttgttat accacatata aggatttgta
    24241 atagctaaaa acagacagga aagttgaaat ctgtgaatct tattttgtat ggaaggattt
    24301 atagaacgca aaaatcaaga taaagatgaa taaaaatcct gtttcggcta tatattgcgt
    24361 atctacgcca ataaaacgag tttgttctgt catagccata taaagcaaag gcaaaaatac
    24421 aactacagcg agataagatc cgatgatttc tcgaaaagtt ttccaggaag tatgtttcct
    24481 gtttttatat ttatccgatt tcattgaata gtcatagcct ccttattctt tcatatgttg
    24541 aaattccagt ataaaaactg gaaggaactg tacgtttttt agaataaaaa ttataaggga
    24601 taagtaggct gctgtctata ataagatata tttttcaatt ctttattaaa gattttattg
    24661 acaaaatgaa tccgttttct atgatggagg aggggtgaat aagttgttga agaaggaaat
    24721 tttatgttac ttagagaacc agacagcctt tttcgattta gaacatatga acgaggtctt
    24781 tacagcacaa aggttagctg atcattttgg ggtaaaaaga aacacagtca gtcattattt
    24841 gaaccagtta aatgatgagc aactactagt caaaatcaat tctcgaccag tgatttattt
    24901 ccacaaagaa gcttttgaaa aacaattttt taagttacgc acgaattttt atttttctat
    24961 cgatgatctc aaagaggaac agcctttttt cgcgcaacca aaagacttat tctcttttat
    25021 gatcggatac gacgccagtt tgaaagaaag tatcgaacaa atcaaaacag ctctttacta
    25081 tccagatggc ggattaccac ttttgattac aggcgaaagt ggcacaggta aaagttattt
    25141 agttaatttg gtctatcagt attgtctgct tcatgatctg ctagaagatt ctgcaccatt
    25201 catcactttt aattgtgcac aatatgcaga taatcctgaa cttttgacta gcaatttgtt
    25261 tggacatgtt aagggagcgt acactggtgc agaagaaaat aaaaaagggg cttttgaagc
    25321 agcagatggt gggatcttgt ttttagacga ggtacatcgc ttaacaccag aaggtcagga
    25381 aaaactgttc acctatcttg atcaaggtgt gatttatcgt atgggagaac ctaatttgtc
    25441 acgccggatc aaaacacgtc tcttttttgc tacgactgaa gagattacta gtcatttctt
    25501 aacaactttc attcgaagaa tacctatccg aatcgaacta cctgcactta atcagcgtag
    25561 tcgtaatgaa cggctagaac tgatttactc tttttttctc gaagaacaaa gaaaaatggg
    25621 gagccctttg tcagtcagtg gaccagcttt gtcactttta acaagtcaga aattatccgg
    25681 aaacatagga gagctgaaaa atatcgtcaa agtttcagca gcaaaagcat atgctgaaca
    25741 gcgtgaacag cctgaaatcc atgtcacgat ccatcatttg caaaaagaac tacttgcgca
    25801 gcctattact aaaaatacag cacagcaagg aatctatatt acgcaagacc agaccttaga
    25861 gcaattaatg gagaagcaac agcccgaaca gcagcgaatc gttaaaagtt ttgagcaaat
    25921 cctaattgat ttcaagaaaa ataactgtct gctatattct tgcgaaggaa aattaaagca
    25981 agaagtgatt caattatttg attttttgct gtttgagacc agtagacaag aaaaacacga
    26041 gctgctggtt tattggacac aatctatccg agagaccttt cgacaaatgg aaactgccta
    26101 tcaaatcaaa ttcgatggaa acagtgtcta tgccttgagt tactatctct atcagcgaag
    26161 cactatcaaa tggttaccgg aagaacatga tattatccaa ctaatcaaag aattagaaca
    26221 acaagtttct cagtcttatc catctagtta tcactatgtc caacgaattc tggaattaag
    26281 taagatcaaa ttagatattg aagacacaag tatggatcgg attttactga cgatctatct
    26341 aaaaaaagcg aaatggtcaa aagaaaaacg actgccaaaa gcgatgattg ctgctcacgg
    26401 ttatgcaact gctagcagta tggcaaatgt agtaaatcgt ttattacaag aggatctatt
    26461 tgaatcattt gatatgccac tagatgtcac accacagcag attgcttcag aaatccttga
    26521 ttattgcgaa aacagcgatg tttcaaatgg attgatcata ttagtagaca tgggatctct
    26581 gaaagaaatc catcagtttt ttaaaaaaca gttatccgta ccgcttttga ttttgaataa
    26641 tgtgacgaca cctttagcaa tcacagtagg ggaatgcctg caaaaaaatg tatcattaga
    26701 agagatagca gaagagactg ttcgacagat ccagccagaa tggcgactgc tctatccaga
    26761 ggaaaacaaa cccaaagcac tcattactac ttgcttcact ggaatcggta cggcggtcca
    26821 cttaagtgaa ctgctagaaa aaagcttacc tacggcttgt cagttgaaaa tcatcccata
    26881 tgaatatcag caattaaaag ataagaaaaa cagtgaccca ttattttcca tatacgaagt
    26941 cgtaggaatg attggcacca cagatcctga tatcaccaat atcgactatc tttcattaga
    27001 agacctcatc tcgggggaaa agatgtctgt actagctgaa tggttggaca ctactatgaa
    27061 tgcttcagag aaggaaatat tcaatcagcg catcattcgt aatttttcat tggaaaaagt
    27121 actggattcc gtgactattc tagatacaga gaaggtgatg ggagaaatcg atcattttat
    27181 gagagaatta gaggtgcagt tgaatcgaag catcagcaat cccaaaaaat tagcgttgta
    27241 tgtccatgtg agctgtctca ttgaacgatt gatccgacaa atgccaatcg aaacctatca
    27301 aggattagag aaatggaagc agtgtcaaaa agaagggtta tctgctatta aatctgcgtt
    27361 tagtgtcatt gaagagcatt atagtgtcat gatccccaat tctgagattg cctatatcta
    27421 tgatattttg agtgaagata cagagtttct ctcgatagaa gaagaatttt gaacataagc
    27481 aagttgttgc cactaatttt ggcatgcaac ttgctttttt agtatgtgta agtgaaaaga
    27541 ggagatgaaa aagtggatag agaaattatc ttagcttccc atggaaaatt tgcttcaggg
    27601 atattagatt cattagagct gatctatggg aaaaatcatt ctattactgt attcgattgc
    27661 tatactgatg agaattttga tttagcggaa acagtaaggc agctttttat gaggtacaaa
    27721 gataaagaaa tcattgttct gacggatctt tttggcggaa gtgtcaacaa cgaattctta
    27781 caatatatca atcgggatca tgtctatctc gttgccggat tgaatttgcc actattgatt
    27841 gagctagtat ctcggttgga cgctgaagta gagacaactg ttttgatcca gcaggtgcta
    27901 actgattcaa aaaaaatgat ccagttttgt aacgagcggc tcaatcagaa aatagaagaa
    27961 gacgaatttt aggaggaaga aaaatgattg tattgacaag agtcgaccat cggttattac
    28021 acggacaagt agctttttca tggacacaaa caataggcgc agactgtatt ttgattgcta
    28081 atgatgatgt acctacgaat gagatacgaa agacaacgat caaattagcc aagccacaag
    28141 gagtcaaact agtgatcaaa tcaattgatg actcgattgc cgcgttgaaa agcggggtga
    28201 cagataaata taagttattc atcgtagtgg aatcgatcga ggatgcatat aagctggcag
    28261 aagcgtatcc agaaatcaaa accatcaact taggagggat caaggcaaaa cctggtactc
    28321 gcagcatcgg aaaagcggta aatattttac cagaagagga ggaacgcttg aaacgattaa
    28381 ttgacaaaca aatagaagta gaaatccgtc aagtaccagc agataaaaaa gtggatgtaa
    28441 gagaagtttt gtaagaaagg aagaacctca atgattgtac aagcagtctt attaggaatt
    28501 gttgcatttg tcgcacaatc agaatatgca ctagggacat cgttgctttc tcgtccgatt
    28561 gtgacggggc tgtttacagg aatcgtgtta ggtgatgtaa aaactgggat cattatgggc
    28621 gcaactttag agttagcatt tatcggatcg ttctcagtag gtgcttcgat tccacctgat
    28681 gttgtgaccg gtgggatttt agggacggct tttgctatta cagctggagc cggtacagaa
    28741 accgcgcttt tactaggttt gccgattgct acgttgacat tgatattgaa aaatatttac
    28801 ttagggcttt tgattccaat tatgaaccat aaagcagaca attatgcaga agaaggaaat
    28861 tataaaggag tcgagcatat gcacttgctt gccggtatcg gtctttcctt gatgcttggt
    28921 gttgtggtaa tggtttctta tatggtggga agcaatacga tcggaaatct attaaatatg
    28981 attcctgact tcgttcaaaa ggggttgtca gtagctacag ggttgattcc agctcttggt
    29041 tttgcgatgc ttgctcgttt gctgatcaac aaacaagttg caccatattt tttcttaggt
    29101 tttgctatag cttcttactt agagattcct gtgaccggag tagctatttt tggtgcgatt
    29161 ttagcagttg tggtagtcaa tattatgaat gtccgtcaac taccacttca aacaactgca
    29221 ggggaggtag aagaagatga agaattctga gatcaaaaac agcaaaataa cgaaaaaaga
    29281 gctaaatcac gtattttggc gttcttttca aatggagttt tcttggaatt atgaacgtca
    29341 gatgaatatg gcttatgttt atgcaatgat tccgattttg aaaaagttat atcagtcgaa
    29401 agaagaaatg gcagcagctt tgaaacggca tctagagttt tttaacacga ccccacatat
    29461 cgttacactg attttaggaa tcacggctgc aatggaggaa gaaaataagg atgatcctga
    29521 atttgatgtg actgcgatcg atagtatcaa aacatctttg atgggacctc ttgcagggtt
    29581 aggagattct ttcttttggg gaactttgcg attgattgcc acaggtgtgg gtacctcttt
    29641 agccatgcaa ggaaatattt taggccctat cttgttcatt ttgattttca atattccgca
    29701 cattctgttt cgctatctag caacaggttg gggatatcgc ttaggaacgg gttttttgaa
    29761 aaagatccag gcaaacggta tgatggaaag tttgacatta ggcgcgtcta ttattggact
    29821 gatggtcgtt ggagcaatga ctgccacgat gatcaccatc aatattcctt taaaaatcgg
    29881 ttcaggagaa aatgctgtga ctgttcaaag tatttttgat gatatcgttc caaatatctt
    29941 atgtcttgga gcatttggca tagtgtttta tctattgaag aaagaagtga aaccattaac
    30001 gatcttgatc ggactagctt tctttggaat ttttggttcg tggataggga ttttttaaaa
    30061 aaggagcaga gaaaatgttt acgatgcaag attatatcta tgaagaaaag gaagtactaa
    30121 gtacgatctt gaaaaagaat gatttttcga caagagaaca tatgaaaaaa acagtgaatt
    30181 tactgatctt agcaacgggt tcatcttata acgcttgttt agcagcgaag ccagcattgg
    30241 aatcttatgg tgatcttact gtcgatattc aagaaccttt ttattttttc aattatggaa
    30301 aactttctcc ttcaatcgat actgtgattg ctgtgtcaca aagcgggaaa agtgcttcta
    30361 ctgttgaagc agtaaaaatg atacaaaaac aagggttacc tgttgttgct atcacaaatg
    30421 acgtgcaaag tccacttgct ttagaagctg cacaaattat tgatttaggt gccggggtag
    30481 aatcagtagg cttcgttaca aaaggctatt ctgcgactgt tttacagtta ctactcttag
    30541 ggataggaat tggaataagt aaaaataaaa tcagcaaaaa aatagaacaa gactacatgc
    30601 aacagttgcg caaaataatc aaccatttac cagcgattat tcaaaaaacg gaagaatttt
    30661 ttgatggata tcaaagttta tttcgtttag cacagcgttt cgtcaccatt ggatatggtc
    30721 caaactgggg aacagctaaa gaagcagaga cgaaattgac tgaaacaatc cgcgttccgt
    30781 cacaaggatt tgagttagaa gcttatatgc acggcccata cctggaggca gatgcttcgc
    30841 atttgctatt ctttattgaa ggggaaagtg taaataagga acgttcgcaa aagttgcaaa
    30901 gatatatgag tcggtacgtt ggagagactc tcaccattac cacaaaaaaa gcaagaaacg
    30961 agaaaacact tggattagca atagaatgtg atgaatatct gtctgtatta gcgcttgtcg
    31021 ttccgtttca actattcgct tataaaaccg cagtagctaa aggtattgac ttgaacaaaa
    31081 agatttttga agactttgat acagtcttga aaagtaaatt ataagaggtg gaaatcatgc
    31141 tgaaattcaa tgaagaagaa caaatcaaag caataaaagg cgcactagct ttacgtccgc
    31201 aagtagaaga aatcatcgat aaactttatg cggaaaaatt tgacgctgtc tattatctag
    31261 gaatcggtgg aacgtatgct tcctcgatgc aagctgtcac ttatatgaat gggaaaagca
    31321 acttgcctgt ctttgtacag catgctgcag aatattacac tactggaaac aaaagattaa
    31381 caaaagattc tatcgttatt ttgtcctctg ttaccggtac aactcaagaa gtagtgaaag
    31441 cagtagaaca aatcaagaaa gtaggagcga cactgattgg atttatcgat aaagcgaaca
    31501 gtaagttgtc tcagctatgc gattttgtgg tcacttatcc agctcctgga acagaacaaa
    31561 tcaaattttt tatggcagca gatcgattga tgtatttgaa tggagaattc gaagcttatt
    31621 cagaatacta tgaacagctc gaacgttatt taccaacagg gttagtggaa gcagagaaaa
    31681 aagcagatgc atttggctta tcatttgcag aaaaacatcg acgtgatagt atgcattatt
    31741 ttattggagc agggaatcaa tggggagctg tttattcata tgccatgtgt tactgggaag
    31801 aacaaagctg gcttccatcg aaatctatcc atgctgccga gtttcttcac gggacgttag
    31861 agatcgtaga agaaacaacc ccagtcacat tatttttagg cgaagatgaa cagagagtgt
    31921 tatctgaacg tgtggctaaa cttttgccaa aaatttgcag caattataca ttgatagaca
    31981 caaaagacta tccagtagaa ggtatcagtg aaaaatatcg cggacgtgtt ttgtctttct
    32041 tattgatgca tgtagtgaca caacgcatcg atgctcatgt ggagcagttg aactgccatc
    32101 cattagagat acgccgctac tatcgtcagt ttgattatta ggatagactg gataaaaaga
    32161 atataaaaaa taaagagagc agcgataact gctcccttta tttttttaaa atattggcat
    32221 caattacgtt ataaaacaca ttttttgcat tatctacagt tcaacttata atctgtttaa
    32281 tgggacatgt gggtgccaac cattttttgt tatgcaatag tactatttag ttgttgcatg
    32341 gatccgtagt aaaagtccaa gtacaacgag ttgcgccagt ttacatagcg ttttgtatcc
    32401 agaatgttga ctaaaacaaa agttcctatg tcaaccgtca acagagacaa tctgtccgtt
    32461 gcaggacctg acagatttag aaatgttcaa tctgtctctt atgtatttta aatcaatact
    32521 cactaggaga agtttcctaa cctcctaata gtaatgctgg tagtaacatt gtcaaaactg
    32581 cttcctctta ggaacaagca aagcataacg agtgtaaaaa taaaatgtag actattgtaa
    32641 catatcattg attatttcaa gtaaaaacga taaaagaagt aaacaaacac ttaaaaacaa
    32701 tggaaattag tcccaacttt aagaaatgta tactataatg gaaattatca attatttatt
    32761 tggaggaata tccatgaaac aaaaaatcgc agttcttggt cctggatctt ggggcactgc
    32821 tttagcacaa acattggcag aaaacgggca tgatgtccgt atttggggaa atgtacctga
    32881 acagattgat gaaatcaata agtatcatac aaatcagcat tttttacctg atttgacgat
    32941 cccagaatcg attatcggat ataaagaatt ggcagaagca gtggataacg cagatgctat
    33001 tttatttgtt gttccaacaa aagcgattcg ttcagtcgca caggaactta ttggtaaaat
    33061 gaatactaag ccaatcatta tacatgcaag taaaggacta gaacaagata cgcataaacg
    33121 aatctcagaa gttttggctg aagaaattcc agaagaaaaa agacaggcaa ttgttgtatt
    33181 atctggtcct agccatgctg aggaagtggc agtacatgat atcacaacaa ttacagctgc
    33241 aagtattgat caaaaagcag cagcctatgt acaaaaactg ttcatgaatg attatttcag
    33301 gatttataca aataatgatg tgattggcgt agaaactggt gcagcactga aaaatatcat
    33361 tgcaattggt gccggcgcta tccatggatt aggattcgga gatgatgcaa aagcagcaat
    33421 catgactcga ggattggcag aaatcagccg tcttggtgtc gcgatgggtg ccaatcctct
    33481 gacatttatc ggtttgagtg gtgtggggga cttgatcgtt acttgtacaa gtgttcattc
    33541 tcgcaattgg cgtgccggta acttgttagg acagggacat aagctggaag aagttctaga
    33601 aaacatggga atggtcgttg agggtgtggc aacgacaaaa gcagcagtag agctagctca
    33661 acagctaggt gttgagatgc caattactca aacaatctat aatgttttgt ataatggaga
    33721 agatatcaaa aaagcagcaa aagaaatcat gttacgtgac ggaaaaatgg agaatgaatt
    33781 ttctcttcgt taaatagatg atcaatagtt aatcgtcgtt taggaggaac agcaagtgaa
    33841 ggtcaaaaaa gcagtcattc ctgccgctgg gctaggaaca cgttttttgc cggcaacaaa
    33901 agccatggca aaagaaatgc ttccaatcgt ggataaacca acgatccagt ttattgtgga
    33961 agaagcattg gattcgggaa tcgaagacat cttgatcgta acgggaaaag aaaaaagacc
    34021 cattgaagat cactttgatg caaatatcga attggaaaac aatttgcggg aaaaggaaaa
    34081 aacagaatta ctcgctttag ttgaagaaac gactcaagtc aatcttcact tcatccgtca
    34141 atctcatcca agaggactgg gggatgccgt gcttcaagca aaagcattta taggaaatga
    34201 accgtttgtc gtcatgctgg gggatgattt gatgaaagat gatatcccat tgactcaaca
    34261 attgatgatg gattatgaag aaacacaagc ttccgctgtt gccgtcatgc gtgtaccaga
    34321 aaatgaaaca tctaaatacg gaattattga tcctaaaaca gatagcgaaa agggtcgttg
    34381 cagagtaaaa gggtttgtag aaaaacctga aatgggaaaa gcaccaagta atttagccat
    34441 tatcggacgt tatctactga ctcctaaaat atttgagata ttagaaactc aagaaccagg
    34501 agcaggaaac gagatacagc taacggatgc acttcagact cttaaccaga cagaggcggt
    34561 ctatgcgaga gagtttaaag gaaaaagata cgacgtaggc gataagttag gatatatgaa
    34621 gacaaatatt gaatatggac ttcaacattc ggaaattggg acttcattaa gtgcatatat
    34681 tatccagttg agtaaaaagc taagaacaga aagttaactg gaaataagtg gcctgctgag
    34741 aatgaaaggc tatttgttat taaagcggca gcttgtgcgt catttgcgca actgtcgttt
    34801 tagttttttg actctagatc agttgagtcg tggaaaacga aagatagaaa aagactttcg
    34861 tgaatagatt cagaaaatat tatgctaatg gtttaatttt tttttaagtt gtataaaaga
    34921 aaatgattac ataagagaaa tgaaagccaa gccagaagat tcatagtaga ataaaaaggc
    34981 gaatttttta attataaaaa aaggtgtgtg ttcactatgg gaaaattagt cgctgttgca
    35041 cagtcgctgc ttgatatact caagtggctg atggaaggaa gcaattggat atttgtgttg
    35101 ccactattgc ttattagtct atttatcatg tttcgcatgg tcagaaaaaa agaaacgttt
    35161 ctgattttta tctggtatgc agcatccgtt ggggttgcta ccttgatggt tgaattggcg
    35221 ttaggtagtt gggaagcttg cgtatttgct ttattttttg ctgtactgta tctaatcatt
    35281 tatatcccat atatgaaaag aaagtctcgg ataggcagaa aaggtagaca tacaactact
    35341 ttttctagta cagattctct cgaacaaagt agaagaacga gaagaagacg gtaatattta
    35401 gtaggtatac gcaaaaaaag ataaaataat ggataaacta ttgagatgag agatttattt
    35461 aattggtgga aaaaagcttt tttcacttat ataaaagaat cttttttaaa ggaatgcttg
    35521 ttgtatcggg ataagccatt ccttttttta tgttatttat atatatataa atcataccaa
    35581 tgtttttttg tattttcttg cttgcacttg gataagagat tacttacaat aaattcagat
    35641 agaaacagct gaataaaaaa aggctccctg acccttagtt ggcgctaaga atcagggaat
    35701 gaccagtcac acacatacac cctgaccgat cattttgcca tagtcaatgc agtgcatcga
    35761 cctaatttat tgtacctaat ctagggtgaa aattctaccc ctatgtagat attttccatg
    35821 gtctgcacgt tgttttattt gctatgtcaa ggtattgggc gtattcgttc aatgcctttt
    35881 ttgtgtttga aacagcaaag accacatgtg ttactgtcta actactgttt ttttatgtac
    35941 ttccttagat taggcagctg tttctattca tgtcaagtat agctaggcgg gagagataaa
    36001 tgagtttatg ttattttgac tattatcacc aattggaaga gaaattaagg atagaagagc
    36061 cgctgatgct tcaagctggc acttggatcg cgaaacaaat taatcaaggt ggtagattgc
    36121 agatatatgc tagccgcaca ctaagtggtg tagcatttga attttgggat caaaccccgg
    36181 atcttgtacc aagtatattg attgaaaatc cagccggagg tgtctatgaa acgctagaag
    36241 gtgcaggaca ggcaattatt gatcagcttt ctgtcaaatc agaagacatt tttcttcttc
    36301 tttcgaatga aggaagaaac ccggcaatca tcgaactagc tcagtggatc aaagaaaatg
    36361 gtcatccatt aatcattgtt actggatttg atttgtcacg aagtatcaaa tcgcaacata
    36421 gcagtggttt gcgattattt gaatttgctg atttggtttt ggacaaccac gccaatttac
    36481 atgatgcagt cttgactttg ccaaatctag atccagcgat ctgcggaaca gcctctcttg
    36541 caacgatctt tttgctgcag caagttttgt attttacagc aaaacagcta gtccaggaca
    36601 caagtggaaa atagttatcc acatgttgac aaagttcctt aaaaaaataa tgttccacat
    36661 aaaaatggag cgtttgaaaa aaagaaaacg attattaatg aggattaaca acgactactt
    36721 tttttgtttt agttatttta agatggatca tctttgattt taagcttgtt ttgtttaaag
    36781 tttgttattt ttataagttg tttcacagtt atgagaaatg agttataaga atatgtagtg
    36841 tcagaaaaat aaaaagtagt ggaaaaagag acaagaaaga atccatatgg attctttctt
    36901 gtctcttaat acacgttgat gaaagagtct tccccaaaac tctttacaaa gtaattatag
    36961 tacatttgtt atcattattg caatgaagtt tacctgatat aacaaaattg tccaacagga
    37021 tacctttttc taatagaaat aaaatacaca aaaattgaag gatagataat ggatatttat
    37081 aagtgtttat tatttttttt gcaatgaaat tcaatttttc aatgattgta aaatgaaaaa
    37141 aacaggacga gattttctct aatctaaaaa taaaaaaaga attttaagga aaaacagaga
    37201 aataaaatac ttaatataaa tggaaagaga aaaaaataat catacatagg agaaaaaaaa
    37261 caaaatagaa aaaagtgatt ttctaataaa ttattcatgt ggaaatgtca tttttactgt
    37321 ataattcatt tgattatcca ttttttattc atcaaaatta ctgaaaaaag aaaggaagaa
    37381 ataaatttga agaaaacaaa ttcttcagga aaaccgaaac gcgacttcac taaattatcg
    37441 acaccccata cgtatgtcat tatttttggt gtagtcatct ttgcatggat actgactttt
    37501 gtcgttccag caggaaagtt cagcacgcaa gatattgaat acaaagatgc aaatggcgaa
    37561 acaagtactc gtactgtttt acgtcaagat tccttccgtt atgcttacga gctggataag
    37621 tcgtatgtgt ttgatcaatt agaagaactg caagatcatc cagcagaacg tgaaaaactg
    37681 gatgttccgg aaaaaggatt ggaaaaagtc attgctgacg gagaaaaaaa tcttacgcag
    37741 gaaaaactag atgaaatctc cttgacagat gatgtgcttt acgatcagta cggcgaaaat
    37801 atctatgata cttctaaaaa attgcataaa acagccaaaa tatggggaac agatgatttt
    37861 ggcggctttg gtttcttaaa ttttgttttt gaaggactag tatctggaga taagtatgga
    37921 tctgctgtag ggatcgctgc attgatcctt gttgttggag gtgcttttgg tattattatg
    37981 cgtaccggag cgatcgacgc aggtatctat gcgtttatca gtaaaactaa gggactggag
    38041 cgtttagctt taccgctatt attctttgct ttttcattcg gtggcgctac attcgggatg
    38101 gcagaagagg taattccatt ctcaatggtg atggttccat ttgtcattgc gttaggatat
    38161 gactcgatcg tagcagtaac cgtgacttat gtcgcatctc aagtcggaaa tgcgacctct
    38221 tggatgagcc cgtttagcgt agcggtggct caagggattg ctggaatccc cgtgttgtct
    38281 ggtgcgacat tccgattgat tatgtgggta gttgttactg cattagccgc tggttatatg
    38341 atgatatatg cagaaaaaat ccgtaaaaaa ccagaaagtt cgttgactta caaatcagat
    38401 gattatttcc gttctcatat caaaaagaca tctgatgaaa ataaaaaatt catgcttggg
    38461 cataaattga tcttattaga gatgttagtt gtccttgtct ggatcgtttg gggcgtgact
    38521 caaaaaggct attacattcc agaaatcgct tctcaattct ttgtgatggg attagttgct
    38581 ggaatcattg ctgttctttt caaattagat ggaatgaaag tcaatgacat cgcttcttct
    38641 ttccaatctg gtgcagctga tttagctggt acagcaatcg tagtaggtat ggccaaaggg
    38701 attcttcttg tcttgggagg atctgatgca tctgttcctt cagctttgaa tacgattttg
    38761 catgggatcg ggacggcgtt gaccggtgtt ccagctgtca ttggtgcttg ggcgatgtac
    38821 atcttccaaa gtttgttcaa cttggttgtt acatcaaatt caggacaagc agctttgact
    38881 atgccaatca tggctccact ggcagattta gtaggtgtat ccagacaagt agcagttctt
    38941 gcttatcagc ttggttcagg ttttatggac gcttttacac ccgtatcagc cagcttgatt
    39001 ggtgtgctag gtgttgcacg gatcgaatgg gcaaaatggg caagattcca aatcaagatg
    39061 caaggattcc tgtttgtttt aggaactatt ttcatcatga ttgccattgc aataggtctg
    39121 cagtagtact ggagacctgt aaataaaaaa gtaatccaaa cagtagataa ggactccaag
    39181 aaccgtcatt ttacggtaaa atcaaaggag taaagatcct atcgtttgga ttatttttta
    39241 agatcctatc atcagttata cttaaagaaa gaggaaaaat gtatgaaaat cattcgacaa
    39301 attgaagtgt ttgcaccaga ttacttagga aaaatggatg tactgattgc cggtgggaag
    39361 attttggctg tagaagaaca gctagaaggc ggctacgaag gagtggaagt agaagaactt
    39421 tcaggtgagg gaaaagtact aaccccgggt ttcattgact gtcatttcca tattttaggt
    39481 ggaggaggag aaggcggtta tcaaaatcga acgccagaag tcacattgag ccaattgact
    39541 acagctggtg taacgacagt tgtcggttgt ttgggaacag acggagaagg tagagatatg
    39601 actgcgttga tcagcaaagc gaaaggtctg gaagcagaag gaatctccac ttatgtatac
    39661 gaaggttcgt accgattgcc ggtaaaaaca gtaacagatt ctatcatcaa agactttttg
    39721 acaattgata aaattatcgg aatcggagaa atcgcagtat ccgatcaccg ttcttctcag
    39781 ccaagttttg aagagttcgc tcgtgcagta gcagatgctc gtgtaggagg catgttatcc
    39841 ggaaaagctg ggatcatcaa tgtccactta ggcggaggaa aaagaaagct agagctattg
    39901 acacgaatcg tagaagaaac agaaattccg atcacacaat ttttgcctac tcatgcaaat
    39961 cgcacaccag aattatttga agcttgcgtg gcatttgcca aacgtggtgg cacgattgac
    40021 ttcactgcta gcgaagatcc tgatttttgg gagaagacag atggtgaagt tcgcttcagc
    40081 aaagcactga aacgattgat cgaggaagat gtttctttag ataatttcac gatgacctca
    40141 gatggacaag gaagcttgcc ttattttgat gaaaacaatc atttcctagg gttaggagta
    40201 ggaagtgcca aggcattgct agtagggatc aaagaagctg tgcaaaaaga aagtatccct
    40261 ttggaaatcg ccttacgagc tataaccagt aatccagcac gtatattgaa attggataaa
    40321 aaaggaaaaa tcgaaattgg tgctgatgca gatctgtgta tcttggataa agaaacgctt
    40381 gatattgata cagttatcgc taaaggagaa ataatggtcc aagaaaaaga agtcaaagta
    40441 tgggggactt tcgaaaaaag tttttaatca acagctctaa ctatcttttt tagaaaacga
    40501 gcgttctgtt tgtctgtatc tgttgttgat gttaccctga aggtagatca ataaacaaac
    40561 taagaggagg aagcacaatg gcagatttaa aaggacgttc taaagatatg aaagataaag
    40621 tagtcggtga aggaaaagaa gcatacggca aagcaacaga cgacaagagc aaagaaacag
    40681 aagggaaagc acaatcacta ggtgctgaca tcaaagaaaa agctcgaaat ttaggcgacg
    40741 aagtcaaaga caagttttct cgaaaagacg aaaaaaaata aaaaccactt attactaatt
    40801 gaatcaagca aataaaaaat ccgaaccata tctgcgagac agatatggtt cggatttttt
    40861 atttgatcat tatcctgttt tttaaacttc gattttttga aattttttat tttttagttc
    40921 aaagacttca tcacagcttt ttgctacttc aatctcatga gtcacgatga taatacagcg
    40981 attttgttca tgggcgattt cttggaaaag tttgacgata tcttgtgaag ttgtttcatc
    41041 tagatttcca gtaggctcat ccgctacgat tagttgatgt tcacagcaga tagcacgaac
    41101 gatagcgact cgctgctgct gacctcccga aagtttggtc acctgttttt ttgctaatat
    41161 ttcatcaatt cctacacgag ccagtcgatc taaagcaact tgtcgataat tctcttgctt
    41221 ggtcttagtg atttccattg ctgctatgac gttgtctaga gccgataaat aaggaagcaa
    41281 gttgtaagct tggaaaataa tcgagacatc atttttacga taacttctta acccgatttt
    41341 gttcagtgaa cgatcttgat agtatacctt tccttctttt ggtgcatcta gtccagaaat
    41401 aagcgaaaga aaagtcgttt ttccagaacc acttgctcct aaaatagcgt acatttttcc
    41461 agcttcgaaa ttcagttcta catctttata aagcgcatct tgcggatctt gataccaaaa
    41521 tcccaattgt tctgtccgta acatcaaatt cctcctttag tttaatagga tttttcttgg
    41581 gtttaatctt aatatcccta tagaagctaa aaagacagaa aacagactga ttccaaatgc
    41641 tactccggct aatagtccca attgtgcagg tttgacattg atttccaatt cgctgacttg
    41701 atcagaaaca gcaaatggat tattcgtggt tccttgttga ccatcgcgtt gaccgccttg
    41761 ttcttgtctg ttacctggca tttgtccacc gccaggagct tgctggtttt gtgtcgtggt
    41821 ttctgtctgt tggtcaagta gctgctgtcc cacggcattc gcgacgacgt ttccgctaag
    41881 cgaagcaact cctaatgcaa gaatcataca aatagccact tcggtaaaca attggagaat
    41941 gattttactt ctggattctc ctaaagatag caagacgcct aactcatgcc gacgctcccg
    42001 aatggtaatc ataatgatca gagtaagtat gataataccg gctacagcca ctagtaaaac
    42061 aacattttta gaaaaacttg ccacgttgtt taaaggttcc aacattgact gatacatgga
    42121 atcatttgat tgtaagctaa atgtatctgt gtcgatcagc ttctcagctt ctttgagaaa
    42181 ctcatccatt ttatctggat cagatagagt gtaaatagca gaatctatcg tgttatcgtc
    42241 agatgtccca tttagttcat ttgcaaaagt gtaagaagtg taaagtgtat tcgacggatt
    42301 catgaagttg aatttcatac ccatactgcc gcttgtttcg ctggattcat aaattccttt
    42361 gatcgtcatt tcataagtgg tatcttcatc ttcagtactc gtgattgtga aagtatctcc
    42421 gactgccagg tcatttgttt ctgctagagt agaatcaatg actacattgt ttgtgccttt
    42481 gtcgctgtca tctattcctt caccatccgt gatttttgct gttccatcag aaaaattact
    42541 attttgtgca gttgctgaca caccactgat ttgaaagtct gcttgagtca tttgcggatt
    42601 cccgcccatt cctccagcag gttcaccgcc tgcatcagta gtttctgaac tgtcttcact
    42661 tgaatcagaa ctagtgatgg cagttattcc atcttttgcc atagctgagg cggaactttc
    42721 aaaggaataa ctctttacat tatctaattc agctattttt tccgcgtccg ttaaggaaac
    42781 tggtgtaaga gaaaaactgc ctggatctgg acgttcttca gtggtagaac cgcttgaaga
    42841 agtttgttcc tgttttttaa atgaagcttc tcgattggca cttaaagtca ctgttgctcc
    42901 aacttctttt tgtgcttgat tcgctgcttc ttctgcagcg cttcgaatcg tgaggccagc
    42961 tagcacaaaa ataagaatgg ctgtgaacac ggcaaacaat aacaatgaac gtccccattt
    43021 tacttttgta cttttccatg cacgtttcat aaaattcata ttttgcatcc ctcctagtag
    43081 atgcatttga taatagacaa cctatcttaa agctagctta aatcttatgc tgtttgcaca
    43141 ccatcaacat gaggttctgt atatataaaa agtcactata gttattgcaa aaaatgtggt
    43201 aaaatgaaaa aagtatgttt caaaccgacg aagaagaaat gaaagaggaa tagcaaaaga
    43261 aatcctagat gctacagagg gatttttacg tgcatagttg ttctaacaat tgctgatact
    43321 agcgatttag tttatttgtt gtataataat ggggaacagc tgaatactta tataagtatt
    43381 ctggctatag cgtttcgcaa aagatccatt ttgttaatga agtatatcca aaataaaatg
    43441 cccatccaac tgtcagaacg cggatgtgct ggtaattttc ctgctgattc tccataagtt
    43501 gagaaatagt gattttgcat atgcttcatt ggaatggctc atatatttag ataaagaaga
    43561 aaatcgacat ctttaaactt ggatgtcata agaagaggtg aagtttgtga gtaccattaa
    43621 aattatccca ttaggcggcg ttcgtgaaaa tggaaaaaac atgtatgtcg cagaagtggg
    43681 cgaggatatt tttattttag attgtgggct aaaatatcct gaaaatgagt tgttggggat
    43741 cgacgtcgta atccctgatt ttacgtattt agaagaaaac attgatcgtg tagctggtgt
    43801 ctttttaaca catggacatg cagatgcgat cggggcactt ccttacttgt tgtcaaaaat
    43861 ttctgtacca gtattcggga cagagttgac gatcgagtta gcaaaattga atgtcagtcg
    43921 taatgaagca gccaaaggat ttaaggattt ccatgtggta gatgagcata cagaaataga
    43981 ctttggtgaa acagtagtga gctttttccg taccactcat acgataccag attcagtggg
    44041 gatcaatctg aaaacaaaag aaggtagtat cgtttatacg ggagatttta aatttgacca
    44101 aacggctatc ccaatgtatc aaacagatta tgcacgattg gcggaaatcg gcaaagaagg
    44161 agtcttagcc ttactaagtg aatcggcaaa tgcagaaaat cctcagcctg tagcttctga
    44221 agcccaaata gcagatgaag tatttgatac gatcaaatat tgggaagggc gtatcatcgt
    44281 cgcttgtgta gcaagtaatt tgcaacgagt gcaacaagta ttggatgcag cagaaaaagc
    44341 acaacgaaaa gttgtcttga ctggtcaaga tttcgaacga attattcgca cagcgatgcg
    44401 tttagaaaaa cttcaattac caagtgaaga tctgcttgtt acgttgaaag acatgaaaaa
    44461 ctatgatcca gaagaactga tcattttaga aactggccga atgggtgaac ccatcaagtc
    44521 tctgcaaaaa atggcaaacg gtacacaccg taatgtcaag attgaagaag gagatttggt
    44581 ttatatcact actacgccaa gcatcgcgat ggaaaccatc gtggcgaaaa cggaagatat
    44641 catttatcga gctggtggaa cagtgaagtt gatctctgag aatatgcgcg tttctggcca
    44701 tgccaatcct aatgacttgc aattaatgat caatttgatg aaaccaacat attttgtgcc
    44761 agttcaagga gagtatcgtg aattagctgc tcatgcagat ttggctcatg cagtagggat
    44821 gccatacaaa aatatctata ttactggacg cggagacgtg ctggaatata agaacaagcg
    44881 tatgagtgtt gcaggaacta caagtgcaga aaatgtaatg attgatggat taggcatagg
    44941 tgatatcgga aacattgttt tacgtgatcg aaaaatcttg tcagaagacg ggattttcgt
    45001 agcggttgtc actatcagtc ggcgagaaaa gaaaatcatt tcaaaacctc aaattacttc
    45061 acggggattc gtttacgtaa aagctagccg tgatctgatg aaagaaagca gcaatatgat
    45121 tgaaacaatc gttgagaaac atttagaaag caatgatttt gagtggagca aattaaagca
    45181 agacatccga gatcaattag gccgttactt atttgaacaa acaaaacgcc gcccagtgat
    45241 cttgccagtc attatggaag ctactcaacg tcgaaataaa aaataaacaa aaagagtaag
    45301 atgaacctct ctatagagtg ctcgtcttgc tctttttttg cgaaaaacaa ataatttttg
    45361 aatacagcat ccctcgcttt ataataaacg atagaataaa gggagtgaat caatgatgag
    45421 tcaaacaaaa gtcgaacgtt atttagaaga acaaaagatc agctatcaac cacttgattt
    45481 tagtcatgtg gtagaagaat ctttcacaga agaactacaa aaaagaggga ttgatccagc
    45541 tttgatatgt aaaactctcg tagtgaaagg aaacaaaact ggggtgatca tcgcattgat
    45601 tcctttgaac gatcacttag attacaaaaa aacgagacaa gtgacgaaag atcgtaaagt
    45661 tggttttcct ggaatggatt ttgtattaat gcatacagga tatccccacg gagcaaacac
    45721 ccctattgga ataaaactcg cacatcctga ttattgtttt ttagcagaca gttctttaaa
    45781 agaaaaagaa gaagtaattg tgtcaagcgg tgaaatcggg agaagccttc ggataaaagt
    45841 agccgattta gaaaagatcg tccatcctat ttacgctgat ttaattagtt aagggacgag
    45901 aagagaagct aagcagagca gagacctcaa acttgagatt atatctgctt ggtacttggt
    45961 gcatcctgta ttatctgtta caattgcttt gtacatactg tactatcaat ccaatgaaaa
    46021 tatatttagc agctatattt tttcattgat gtgcaagtga tgaaatcgtt tttaataaaa
    46081 aagatacaga gaaaacgcga ggtgtaaaat atgaaaatta cgtatcatgg acattcctgt
    46141 ttaacaattg aaatggaaaa tggccaacgc gtgatgattg acccgtttat tacaggaaat
    46201 ccattgacag acttaactgc agaagaagta aagacagatt ggttgctgat tactcatggt
    46261 catagtgacc acataggaga tatgattcct attgcaaaag aaaatcaagc cacaattatc
    46321 agtattgttg agattgctga ttatgcgaac agcagaggag tagattcatt cggtatgaat
    46381 atcggtggaa aacatgcgtt tccattcggc gtggtaaaat tcgtacatgc acagcatagt
    46441 tcaagctatg aagtagacgg tatcgttcag tatatgggcg agcctagcgg aattattatt
    46501 caagcagaag gaaaaacgat ttatcatgca ggggatactg cttatttcag tgatctagga
    46561 ttgcttgcag aagaattcga tattgatgtc gctttcttgc cgattggcga taactatacg
    46621 atggggccag aagatgcagc aaaggctgcg caaacaattc gtgccaagaa agtagttcca
    46681 atccattaca atactttccc tgtcattgaa caagatcccg aatcttttgt agagttactg
    46741 gaagatagtg aaggaaaaat aatgagcgtc tcggaaacgc tggaagtgta ggcagaaaat
    46801 ggcgacaaaa catgatttga ttttagaata tattgaaagt ttacctgttg gcaatcgaat
    46861 ttctgtaaga agcatcgcaa aagaattgaa tgtcagtgaa ggaacagcgt accgtgcaat
    46921 caaagatgca gaaaatgtcg gactagtttc aacaattcaa cgagtaggga ccatccgtat
    46981 cgaacgcaaa ttaaaaaaac atattgaacg tttgacattt ggcgaggtcg tcaggatcat
    47041 tgaaggggac gttttaggcg gggcggcagg attagacaag gtcttgaata aattcgtcat
    47101 cggcgcgatg actaaacatg ccatggaacg ctatattacg ccaggatcac taatgatcgt
    47161 cggcaaccgg gcggaagtcc aaaaattagc attggaagat ggcgccgcag tattgatcac
    47221 aggaggattc aatacgactg ctgagattgc aaagctagct gatgatcttg aaatgccgat
    47281 cttacgcacc tcttatgata catttacagt cgcaaccatg atcaaccgag cgttaagcga
    47341 ccaattgatc aaaaaagata tcatgcttgt cagtgatatc tatatgccag ctgaaaagac
    47401 tcattatttg cagcagacag atacgatttc tgattatcag cgtttgtcag aagaaacgca
    47461 gcattcgcgt tttccagtcg tcaaccgcca tcatcgtttg atggggattg ttacggcaaa
    47521 agatgtttta gggaaatcgc caaaccagat catcgatcgg gtgatgacga aagaaccaat
    47581 cagtgtaaag aaaacaatga gtattgcctc tgttagccat caaatgatct gggatgggct
    47641 agaagtcatg ccggtcgttt ccgatgactt gacattggaa ggcttgatta cccggcaaga
    47701 tgtaatgaaa gcgatgcagc ttgtccagcg acaaccgcag attgcagata cgatttcgga
    47761 tcagatatct ggaaatatcc atacgattga tactgaccgt gaaggaaatc gtttggaaaa
    47821 ccctaagttc aaattcgtag tagcaccaca aatggtcaat ggcgttggaa ccatttcttt
    47881 tggcgtactt agcgaaatca tttctgatgt cgcacaaaaa acaatggtga tgaaccaaaa
    47941 acgaaatatc ttgattgaac aagtgaacct acattatttg cggctgatcc aattggaaag
    48001 cgaattagac attcgtccac gtgtattgga aatcggcaga cgttccgcta aactggatat
    48061 cgaagtgttt attgaaaaca ccatagtttc caaagcaatc gttgtttgtc aagtaatgga
    48121 acgttcttag aaagcaggag tgaaatgaca gtacagcaag aaatagtaga tacaataaaa
    48181 aaatacgata aaatcattat ccacaggcat ttgcgccctg atcctgatgc attaggatca
    48241 caagtaggat tagccgaact attacgggaa agtttcccag aaaaagaaat acgtcaagta
    48301 ggtgaaacga ttgaagggct tcgcttttta gcagaaatgc aagaagttga agatgtcttc
    48361 taccaaggag cgctagtcat cgtgactgat acagctaatt cacccagaat cagtgatcaa
    48421 agatatcagt tggcagaaaa actgatcaaa atcgaccatc atcccaatga tgacccttat
    48481 ggagatcttg tgtgggtaaa tacaaaagca agtagctgta gtgagatgat tgcagaattt
    48541 gctttgatgt ttcctgaatc tttaaagatg aacgttaagg ctgcacggtt actttatgca
    48601 ggaatcgtcg gagatacagg gcgctttttg tatccctcca cgacgtcccg tacattagag
    48661 attgcttcga tattgagaaa ttatccattt gatgcaagtg ctttgaacag agagattgaa
    48721 caaatgccga tgaaagtcgc taaactttcc ggttatcttt atcaaaatat ccaggtggat
    48781 gaaaatggtg caggaagaat aatccttccg caagaaattc ttgataaata tggaatcgat
    48841 gattcagaga cagcttcgat cgtttcactt cctggagtga ttgacgaagt gctggcttgg
    48901 gggatttttg ttcagcagcc ttcagggtat taccgcgtac gtttacgttc taaggggccg
    48961 atcatcaatg aattggctaa acgccatcat ggaggaggcc atccattagc aagtggtgcg
    49021 aatgcaaaag atttagcaga agtagaggaa atctataaag agatccaaga tatatgccaa
    49081 tcgtataaga gcagaaaaac agaatgatac ttcgttcgaa aacgtgcctt ttgtagtaaa
    49141 aatcacaaat gtatcttttc aagatcttct ttttccgtta caatagtgct cactaaagat
    49201 tttaaaggag aaagaagatg acattaccaa attgcccaga atgtggctca gagtacacat
    49261 atgaagatcg aggcttgttg atttgcccag aatgcgggaa cgaatggaac aaagaagaac
    49321 aagaaactgt catagaagac ggattagtgg tattagatgc aaatggaaac cgtctgttag
    49381 agggcgatag cgtgacagtg attaaagact tgaaagtaaa aggtgcgtca ggtgccatta
    49441 aacaaggaac aaaagtcaag aacatccgtt tagtagaagg cgatcataat atcgattgca
    49501 aggtagaagg atttggaccg atgaaactga aatcggaatt tgtgaaaaag aattaaagaa
    49561 tattcaaggt cttttcacat tcttttccta ctactaatga taaaataaag taaacgaaaa
    49621 ggagtgaaac gaaaatgtat ggttatggaa tgtatggttt tttagatccg acatttcttt
    49681 tggtcattct tggattagtt atttccggaa ttgcgtcagc gtacgtcaat agtactttcc
    49741 gaaaatacga tcaagtgaga agcaaaaaca atgtgactgg tacacaagca gcacaatata
    49801 tattacaaag tcaacagata aataatgtcg gtgttcaaca aattgccgga gatctcacag
    49861 ataactacaa ttcaggtaat aagatgttga gtttgtctca agcaactgca cagtctactt
    49921 cagttgctgc gataggtgta gcagctcatg aatgcggaca tgcggtacaa gatgcttcgg
    49981 gttatgtccc attgaagatt cgtgcagcac ttgttccagc agctaacttt ggttcgatga
    50041 tttcgttccc cttgattatg gtaggtgtat tgcttagctg gaactctacg ttaatcaata
    50101 tcgggatttt cgctttttct ttagcattac ttttccaatt ggtgacatta ccagtcgaat
    50161 ttaacgcgtc tcggcgagca atccaaattt tgagtgaagg cggactactg acggaagaag
    50221 aagtaccgat ggcaagacac gtattatttg cagcagcact gacttatgtt gcagcagcgc
    50281 tttcgacatt cctgcagctg ttgcgcttga tcttattgtt cggcggcaac cgaagagatt
    50341 aaaataaaga agttgtgaaa tcagcgcttt gatctgagct aataccgaga gttagctgat
    50401 tgaataccat ttatttggaa taagaggatg tgacaagaat tttgtcacat cctctttgtt
    50461 ttgttctcat aacctttttt catatacagt tcatgaaccg cttttattaa cttgccaaat
    50521 aacactgtat tgtgcgttgt atccagatag aaagtctccg tttcatctga aattttctca
    50581 tgctgatctg taatgatcaa atcagcatgt tctgaatatg cggtaatttt aacagcatct
    50641 ttgcgaaata actgctgcaa atggctttga agatgataat ttcctgtaaa ctgtttggtt
    50701 atctgcaaat ggatgagtaa ctgctctttc gtttctgttt gtagtaagtg ttggatcaat
    50761 tgactaaggt attgactgat ttggtttctt tccccatttt ttgaaaaaat tgtatcgatt
    50821 ttttctctta atttcttttc ctgtataaaa gaactagaat gattggacgt ggcttctgga
    50881 aagcaaagtg tagaaaaact actgctggat tcacccaaca gttcgaaaaa aacaactgcc
    50941 aacacaagaa aataaaaata aattggtatt ttattttcta aatggttgag aggaaactgt
    51001 tgagttaagt aagtcatcaa ttgaccgact tgtcgacaaa taaggttttt gcttgtggaa
    51061 aataaaaaac caatctcctg tttttgtcga aaagagattt gatttggaaa aaaacaatag
    51121 aaaaaataat taaagtaggc tctctctgtt tctgtctctt cacaagggcg actcactgaa
    51181 aaagaagtaa agtattctga ataatcatgt gtatgctgca ataagtccat caattcagtg
    51241 atttcagaag aagtttttgg aaaatatgcc tgttgtttgt ttcgtaatat gaataaagtt
    51301 aacagcaagt agatattttt ttcttgtttt gaaatttttt ctatttgctc atctgtactg
    51361 ttcattttta gtgcatttaa ttcaagtgag gaaaatggcc aatcgttacc tccaaatgta
    51421 tctgaaagaa aaaagtaaag atagagacgg atagataact catttccttc aagagtacag
    51481 caatttttta cagataggat ccgtaaatgg aattttatta aggaatgatt gagctgtttt
    51541 gtcagttttt cgagatagga gggcgatata taaagttgtt caagtaaata tttttttggt
    51601 acagcagttt gtggataatt gattagtaac atcaaatagt taaaacgatt ggattctttt
    51661 aggtagcata attttaactt agaaaaaaca gctaactttt tagtttgatc ggtttctttg
    51721 gtttggatct ctcctttatg attagaataa ataaattcat caatcaataa aaattgcttg
    51781 agtgatacat ttatttttcg gatcagttct ttgattgtcc gttttggaat atgtaagtca
    51841 ttggataatt cttgtaaaga acaattattt ttttgaatga ccatttgtag aacaagtaac
    51901 tctttttttc ttgcttcaat tagcataaat acctcctttt tattctgttt ttgtatatag
    51961 ttagacaaaa actgtgagtg gaaagtcatt tcagtctgtg ttattctcac agagtgtcgc
    52021 cttctttttt atataacgtt atttaatttt tttgttacct tgtttattct attgtttatt
    52081 tcctagggta ttttgtcaag atattcttgt ttttaaggcg gaaaaattga tttttaatgg
    52141 atataactaa atatgttttg ataattatca ataatatttt tagaattatt tatgttattt
    52201 atttatgggt agatgaaaag agacggaggt aagaatgatg gggagagtaa caaattatag
    52261 taaagaatat ttgctgttca aaagtatggt atacgtggaa gaatatggaa tgaagtcaat
    52321 tactgcaaga gagttagcag agttctgcgg ttgttctaca tacccgattt atacacattt
    52381 caaatcaatc agcgggttaa aagagaagat attagaagaa atcactgttt attttgaaaa
    52441 ctacttagct gaatgcagtt ccgatgatgt tttaagcatt gtctacttat tgaaagattt
    52501 tttttctatc catgaaagta ttcgtgaaat cattgcaaaa tctgatttag acatggattc
    52561 gctatttaag cggccatttt tctcatatgt caaaggtcac acgaagatca aagaagaaaa
    52621 gtcgcttgaa ttggtatggc ttaatgcatt gggaagtttg cgctcagatg attcttctca
    52681 agattttctt gaaatgatga acgctgtttg ggataaaaac gaggtgacgg atgaatactt
    52741 ggaaaatatc ttaaaggaac agtcacctta ggcagcaaca tgaaaaagta gatcagccac
    52801 ctttattttt cgtaaaaaag attgtaaaat gtctaacgaa acattggaat gaaggaggaa
    52861 gcgacaacgt taccacagca atttatcaaa aaatatcgtc ttcttttagg cgaagaagca
    52921 tccgattttt tttctgcgct tgaacaagga agcgtgaaaa aaggatttcg gtggaatcca
    52981 ctaaaaccgg caggattgga catggtccaa acttaccata gcgaagaatt acaacccgct
    53041 ccctacagca atgagggatt tcttggcact gtcaatggaa agtctttcct ccatcaagct
    53101 gggtatgaat atagccaaga accaagtgca atgatcgttg gaacagctgc tgcagcaaaa
    53161 cccggtgaaa aagttttgga tttgtgtgcg gctcccggtg gtaaatcaac ccaattagct
    53221 gctcaaatga aggggaaagg gttattagtg acgaatgaga tctttccgaa acgtgcgaag
    53281 attttatcag aaaatataga acgatgggga gtttcgaacg caatagtgac aaatcatgca
    53341 cccgcagaac ttgtccctca tttttcgggc ttttttgatc ggatcgtggt tgatgctcct
    53401 tgttcaggag aaggaatgtt ccgaaaagat ccaaatgcaa taaaagagtg gacagaagaa
    53461 tctccgctat actgtcaaaa acgtcagcaa gagattttgt cttcagcaat aaaaatgcta
    53521 aaaaataaag gacaactgat ttattcgact tgtacgtttg caccagaaga aaatgaagag
    53581 atcattagct ggcttgtaga aaattatcca gtaacgattg aggagattcc tttgactcaa
    53641 tccgttagtt caggacgttc tgaatgggga agcgtagctg gtttggaaaa aacaatacgt
    53701 atatggcctc ataaagatca gggtgaagga cattttgttg caaagctgac ttttcatgga
    53761 caaaatcaga tgcataaaga aaagaagaca cgaaaaaaaa gtaaagtgca aatgacaaaa
    53821 gagcaggaaa aactctggac ggagttttca aatgattttc attatgaagc tactggaaga
    53881 cttttagtgt tcaacgacca tctttgggaa gttcctgagt tagccccttc tctcgatggt
    53941 ttaaaagtcg tacgtacagg tttgcattta ggagatttca aaaagaatcg atttgaacct
    54001 agctatgcat tagcgcttgc tacaaaaaag atagagaata taccttgctt gccgatcact
    54061 caaaaggaat ggcaatctta cacagcagga gaaacatttc aacgtgatgg gaatcaagga
    54121 tgggttttgc tagtattaga taagatacct gtcggatttg ggaaacaagt aaaaggaaca
    54181 gtaaagaact ttttccctaa aggattgaga tttcactgag tggattagtt cgtttatttt
    54241 tttgtctatg ctatgatgga gatagataaa aaggagctga tacttatgaa aacatcaaca
    54301 aaagtaacaa tcggattaag cgtagcagcc gctgccagtg tagcgacagc agtcgttgta
    54361 tcgggaaaag taatggaaaa gatccatcat atgactactc ggacgaaagt aaaaaaattc
    54421 gtctatgaca aatttgatgg aaatgaaaaa ttactagaaa tcgtagatgg tctttcagat
    54481 agtgacttgg attctttgat gggaatgtta gcaaaaatca aatcaggaaa aaagaaaatc
    54541 tctgtttatg gtgattcaat caaagattca accgaagatg taaaagaccg gctaatgcat
    54601 tttgttgaaa aaatgatgta agagaaacta gcttttgaac actattcatt cgaaataagg
    54661 ggttgtgaca aaattattgt cacaacccct ttaatctatc tttaattatg ttcatgaagc
    54721 aataaaagat agcaaaacag taaatcgttg gcttttttta gattgaaacc agactgttct
    54781 tgaaattttt cgattcgata ttttagagta ttacgatgaa gaaacagtgt ttttgcagca
    54841 gagctgacat tgcctaattc attccataat tcttgaatga tcacttccat ttcattttgt
    54901 ttgatcagtt ctatgtaact tttgatcaac ttactatctt ttacagtatc ttttgtatag
    54961 taatgtaaag ccacatcttg catagaaaaa gtacggctgt gagtataaag attgttttgc
    55021 tctgttaaaa aaatttttct ttcttcagca aacaaaggga cgaggtcggt gccaggtgaa
    55081 tggaaagaac caacgaatac agacgttgtc gtatcaaaat cagcatctaa agatagaaaa
    55141 ataccgttga tttcagtagc atcaagataa tcacggttta tttgttcgac taagagcgca
    55201 tctgtgtctg tataaaaaaa gaaatcagca gaatagcgaa ataattccaa aatagtatct
    55261 tgccattctt tttttaagaa ttctcctttt gattcgacgt gaagctggat caaacgaaag
    55321 cttttttctt gaacacaaga agcatcttta aaaagatagt gataccatgg gtgttttttt
    55381 tgatcgttga ttacagggaa taacgctttc aaaaggctgg tttcttgttg agataatgaa
    55441 tcttgtttga tccagataaa agcatcatca attgcaaaag aaaggatatc cgcttctgat
    55501 gctggagagt tttttttctg tgcttgtggg taaagagcaa gtaatttatc cattttcatc
    55561 ttgttcacct cttgtattta ttttaccata gaaaaaaagt tagttacagc ctttttatca
    55621 tatgctaaag taaaacaaga aaaaacaaag gcagggaagg gtaattggta aatacaaatc
    55681 ttgatgcagt agaaaaagaa aaatggatgc gccttgcatt ggcagaagca aagaaagcag
    55741 aaatgcttca tgaagttccg attggagcag tggttgtatt ggatggaaaa gtgattggaa
    55801 gaggatataa ccttagagaa accacgcaag atgctactac acatgcagaa atgcttgcaa
    55861 tcaaggaagc ctgtgaaaaa gtgggaagct ggcgcttgga agatgctgca ctttttgtta
    55921 ccttagagcc ttgtcctatg tgcagcggcg cgatgatttt gtctcgtgta gcagaagttt
    55981 atttcggcgc gtatgatcca aaaggcggaa cagccggtac cttgatgaat cttttggagg
    56041 acgagcggtt taaccaccaa gcatatgtag aaggtggcat tttagaagac gaatgtggga
    56101 tgattttgac tgactttttc cgaaagctcc gccagcgaaa aaagaaatta aaaaaagact
    56161 ggtcaacgaa tgaaaaataa ggtatactat tctttgccga aaggctagga caatggtggg
    56221 cttgtgaagc gtgtcaggtc tggaaggaag cagcactaag caggttccgc catgtgtctg
    56281 attataatga aacgacaaca gactttcggg tctgtttttt ttatttttat agtactgtaa
    56341 aaatgaatgt tcctgatttt ttagccagac tgatttatcg aatattgtac ttatacaatt
    56401 tgcttcaagg caggaaaaac tctgaaatag agcttgtttc aatggaagaa aaagctgcct
    56461 atggtatgat aaagataaag agaggcgaga gggtacatgg aaaaaatagt gattttacat
    56521 acgaatgatc tgcattctca tttagaaaat tggccaagga tcagaaggtt tttggatcaa
    56581 cgtaaacgag aaaacgaaaa gaaagaaaaa acgacaacga ttgcagtaga tctaggtgat
    56641 tttgtggatc gttggcatcc attgtcagaa gcaacgaatg gacaggaaaa tatcttgctg
    56701 atgaatgaag ttggttatga tgcagcgacg ataggaaaca atgaaggcgt aggaaattcc
    56761 aaagaagagt tgaatcattt atacgatcat gctgagtttg atatcatcct ggataactta
    56821 ttcgataaaa atacgctcca gccaccggca tggacgaaac catataaaat cattacaacg
    56881 aaacaccaga cgaaaatcgg actaattgca tttactgctc catttccgct tacttataat
    56941 ccgaatggct gggacatacg gaatccttat gatattttgc cagaattagt cgaagattta
    57001 cgttcacaag tggatgtttt agttttgatg agtcatctcg ggattcagga tgatttccaa
    57061 attgcaaaag aaataccagc aattgatgtt attttaggat cgcacaccca tcatttattc
    57121 agagaaggtc acgtaatcaa tgatgtccaa atagcagccg ctggaaagta cgggcagtat
    57181 gtcggtgaag tccatttaac catcgatgaa gagaaaaaaa tccttaagca ttcagccaaa
    57241 gccatcccta ccgaaacaat gacagctttt acagaagatg aacaagaaat aaatagttgt
    57301 ctagaacgtg ggcatgaatt attaaaagaa aaagaagtag cagatttgcc attttctctg
    57361 agtctagata tcttcaatga gcattcgttt atccaagtag cctttgaggc ggtgaaagaa
    57421 cgaggaaaga cggaagcagc aatattaaac agtggtctgt ttttaactga aattccaaaa
    57481 gggcgggtca atcaggatca gcttcacact gcgttgccgc atccgatgca cttgttaaat
    57541 gtcacattgg gtggaaatga tctgatccgc ttagttttag aaatagaaaa aaatcgtaac
    57601 tttttacgta actatcctat gaagggaatg ggatttcgcg gtaagatttt tgggcagatg
    57661 gtctataatg gaatcacata tgattctatt aaccatcaag tcttttggaa gaacaagcca
    57721 atcgatctga ataaaaatta tacttttact accgtagatc atttgatgtt tgttccattt
    57781 tttccaacga ttgagattgc tggaaaaaat gaatttttgt tccctgaatt tatccgaagt
    57841 gtggtaggag attacttgaa agctcactac ccaatcaaat aaaaacaagg tataataaaa
    57901 aagataggtg gtgaacgcat gtctgcaaaa caaaatgaac agcagaacgt tgagcataaa
    57961 acagaaattg ctaagaaaaa atcatcagct gaacaggaaa caacagtcac cgaagaactg
    58021 acagctgctt tggaagaaat cgttgaggag cctaaagcag aaaaagtcaa aggcgagcta
    58081 gtgacactgt tagatgacag taattttttg ataggtgaaa gacattatcg gcttgtgtcc
    58141 gattatcgtg aaggatttaa tgcagaaaag cttggagaac gttacagtga tgtactagcc
    58201 cgatatgatt atatcgtagg agattggggt tatgaacaac tacgcctaaa aggatttttc
    58261 caagcggata atcgacgggc gcatccagat cagcgaatcg attccttgga agactatctt
    58321 tacgaatatt gcaattttgg ttgtgcgtat tttgtcatcg agagaatcgg cggtaaaaaa
    58381 gaaaagacaa ctcagcgccg aaaaaagaaa aaaaaccata atcgtgcgta tatcgatgag
    58441 aaaaaaggac cagtcgcatc taatcgcaaa aaaccggtta ttaaaaatcg aaaaacagag
    58501 tcagcaaaaa cctctgaaaa agtaaaaaaa caagaacaac ctaaacaagt agaaaaaaca
    58561 aaaacagcat ttacgatcag aaaaagggaa gagtagtgga tgaatggact ataaaggata
    58621 tttaattgat ttagacggaa cgatttatcg tgggacacaa cccataccgg ccggtaaacg
    58681 atttgtggaa gaattgcaaa aaagaaaatt acctttcttg tttgttacca ataacacgac
    58741 taagtcacca gaaacagtag ctaatcgtct agcagatgag tttgacattc atgtagctcc
    58801 agagacagtc tacacagcta ctttggcaac aatcgatttt atgaaagcag atggaaaagg
    58861 gaaaaaagtc tatgttatcg gagaagcagg attgattgac ttgattttag ctgccggatt
    58921 tacatgggaa gaagaggctc ctgactatgt agtggtaggc ttagataatt atctgaccta
    58981 tgaaaaagta gttaaagcaa cacttgctat tcaaaaaggt gctactttca ttggaacgaa
    59041 cccagataag aatataccta ctgaacgcgg ccttcttcct ggagcagggt cagtcatctc
    59101 ttttgtagag acagcaaccc aaacgccgcc gatctacatc ggaaaaccag aagccatcat
    59161 tatggataaa gccgttgaag tattagggct gcaaaaagaa gaagtaatca tggttggaga
    59221 taactatgaa acagatatcc aagctgggat acgcaataat atagatactt tgctcgtttt
    59281 atcaggtttt acaaaagaag aagatgtacc tgggttgcct atcccagcta cctatgtgaa
    59341 acaatcactg gatgaatgga gcttctaata tgaaaaattc gagatggcag tggatggaat
    59401 atgctggatt gttcagccta tttctgacac tgatcagtct ggcagttggt gtgacgatca
    59461 actttcgacc actatacgta tttgatatcg gacatttgca aattttggat tatacttctt
    59521 tagatcaaga gacgttactg aaaaattttg atcacctaat gaattatctc aataatccct
    59581 tcaaaaccat cctcagcttg ccagatttcc cagtttctgc tagcggagcc catcactttt
    59641 atgaagtgaa aattttgttt ttagtggatt atgctgtgtt tttcatcact ttgatcccga
    59701 gtattttgtt tatcaaatat ttgcaaaaga atgatcggct ttggcggttg attcgtccgt
    59761 ttcaaatcgg catgttactg ccagttgttt tcggtttttt catgatgata ggatttgatc
    59821 gcttttttat cctttttcat gaaacgtttt tcaacaacga tgactggtta ttcgatcccg
    59881 ttactgatcc aatcatcaat gtacttccag aagaattttt catgcatagc tttatcttat
    59941 tttttgtatt attagaatta ttttttgctg tttttctttt cttaggaaaa aatagcttga
    60001 aacaaacaaa aaagaaagaa ctcgtctaaa tagacgtttt ctttcttttt ttgttgaatt
    60061 attgagtaag gcgacttctt ttttctggtt ctttgtgtgc taatcgactg gcagcagcag
    60121 cggcgatcgc tccgacgata tcatctaaga aggtatggac atgaacgcca tcgtggctgt
    60181 ttagttcttt taaaatacca ggtttcacct tgtcgatata accataattc gtaaagccga
    60241 tcgtaccgta aacattcacg attgacaagg ctaggatctc atcgataccg taaaggcctt
    60301 cgtcatcttc gataatatgt tgcaacggac tcatcaattt tttcttttct gctaatatat
    60361 ctaattggat tccagtgata atggcgttat gtacttcacg ctttgttagc acgctgttga
    60421 cactttcagt acaatccgcc aaagtcaaat cagaaatata gtctttttgt aaaaacatga
    60481 caagttgtgc gatatcttct acagttacgc cacgttcctt caatagttct cttgcctttt
    60541 cttctaaagt ctcagttttg acgaccatat tattgctccc cctttatttt ttctttctct
    60601 atttcatgtt aacggaacat gaaaaaaatg caagaaactg ctttcgggtt taacttgaaa
    60661 tgcaaagaga tataaaaaat caactaggac gaagattttt atcgtataag cttgtgctgt
    60721 gaccaggctg agttcgttcc tttggattaa tatagtgtaa agcgttgttc actgcagtag
    60781 gtgcttcacc gagcccagta gcaatcagtt tcacttttcc ttcataggta cagatgtcac
    60841 cagctgcata aacgcctgga atagaagtag acatatctga ttttacagta atggcatttc
    60901 tggtactatc aagtccccaa gaagaaagat gttctaaatt agaagagaat ccataattga
    60961 cgatcagaga atcaatcatc aaatcaatcg tctcgtcact tttcactttt tttaaccgga
    61021 tatctgtcag ttccccatta ttgcctgata atccatcgat gagataggga gtaagcaagt
    61081 tgacagatga agatttcaag cgtgatacac tatgttcgtg cgcacgaaat tccgggcgac
    61141 gatgaatcaa gtaaacttcg cttgcaatag gctctaacat caacgtccaa tcgatagcag
    61201 aatcaccacc tccagcaata gcgacttttt ttccagcata cttcatcaaa tcattcacga
    61261 aataatccaa tccgtggttt tcaaatgatt cagcattatc taaattcaat tttcttggct
    61321 ggaatgaacc atttcctaaa gctaaaatga ctgctttgga ataatggatg cctttatttg
    61381 tagtaatctc gataacttcg tcttcacgag taagcgagag aacttcttct tttaaatgga
    61441 atgtatggtt aaaagtagtt aattgttttt ctaattgatc gattaattca cttgctttta
    61501 ttgctggata cccaggaata tcgtaaatat atttttcggg atacaaagtt gctaattgac
    61561 caccaagttg aggtagactg tcaatgattt ttgttttagc ttggcgcatt cctgcgtaaa
    61621 aagcggcaaa catccctaca ggacctgcac cgatgattgt aatgtcatag atttccataa
    61681 aaattcctcc cttttcacac tatatcagaa tttaattgag aatgcttctc aaaaatgttt
    61741 gaattcgaaa tcgaaacggt aagttataga atgtatctag tgatgaaaaa taaaagaaaa
    61801 caaatctagt atttttacga gaggttaggt attatgttat tattattatg aagtatgcaa
    61861 atattaggag gaaacaatat ggcattccca caactagatt taaaaagtga aaaaggacca
    61921 aaagctgtta tcaaaacaaa ccgtggtgac attactgttc aattattccc tgaactagca
    61981 ccgaagacgg ttcaaaattt cattgaactt tccaaaaaag gttattatga tggcgtgatt
    62041 tttcaccgcg ttattcctga tttcatgatc caaggcggcg atccaactgg aacaggaatg
    62101 ggtggcgaaa gtatttatgg cgaaagtttt gaagatgaat tcagtcgtga actgttcaac
    62161 cttcgcggag ctttatctat ggcaaattca ggtccaaaca caaacggaag ccaattcttt
    62221 attgtaaata acacaaatgt gccagctaat atgcttggac aactagaagg tgctggattc
    62281 ccatcagaaa tcattgaagc gtataaaggt ggcggaactc cttggctaga tttccgacat
    62341 acagtctttg gacatgtact agaagggatg gacacagtag atgaaatcgc aaatgtacaa
    62401 cgtggtccac aagaccgacc tgtacatgat gtagtgattg aaacaattga aatttcagaa
    62461 tagtttggta tggtacggag taattatgaa aaaggacgaa acctagtaag gtctcgtcct
    62521 tttattttga ataaatgatt taatcgattg tctctaaagc atacttgatt cgattaagtc
    62581 cttccagtaa agtttcttct ggacaagcaa tattcaagcg catatgccca tgaccggaag
    62641 gaccaaacgt gatgccagga tttaatacga cttttccttt ccgaacaaga gtgttctcca
    62701 attcttggtc gtctgaaata taggcggtaa aatctaacca cattaagtaa gttccttcag
    62761 ggttcattat tctcactttc ggaagatact gttcaaaaaa ctgattaact gtttgaacat
    62821 ttttttctag ataaggaatc agttggctta accattctcc acccgtctca taagccgctt
    62881 gggttccaat cagtccaaaa gtgttgattt cgtgctgttg gttcatcact aaatgttttt
    62941 caaaatcagc tttcatctct ggatttttga taaataccat tgaatttttg attgcagcta
    63001 gattgaaagt cttggttgcg gaagtaaaag caactagtag atcatctaaa ttaggatcaa
    63061 tcgttagcat ggaagtaaat gtatgatcga ataaagttaa atcttgatgg atctcgtcac
    63121 taaacagaat cacttgatgt tttaaacaca attcgcttaa ctgtttcaat tcttctttgc
    63181 tccaaacacg ccctccagga ttgtgaggat tgcataaaat cattgctttt acattgtttt
    63241 cttcgatttt tttctccatg tcagacaagt ccatgatgaa atgattattt ttttctagca
    63301 aagagcttcg aacgatgtga cgttgatttg tttctataat agaggaaaat ggaggataaa
    63361 ctgggtcatg aatcaaaata gaatcgcctg gttttgtaaa agtttgtact gctgcagcta
    63421 aactggttaa cacaccactt gtaaaaacga tattttcttt cgtcaactcc acagcatggt
    63481 gttggcgttc ccaatgaatg atagcctgat atagtttatc agacagagtg gcataaccaa
    63541 agattccatg tttgatgtat tcactaaacg ctttagctac cccaccggga gacaagaagt
    63601 ccatatctgc tacccacaaa ggaagtaagt catccatttg atatgtctca gcaattgcgt
    63661 cccattttac actttctgta tcttttcttg aaatctgttt atcaaattcg atcatcttaa
    63721 gacctccagt cattttcgtc gcttcttttt ttgagctatt tacagtataa tgataaatgc
    63781 gaagagaggg aagtagatga cttataaaat tggacaaata attgaaggaa aagtgacagg
    63841 gatacagcct tatggcgcat tcgtttctct tgataacgag acgcaaggac ttattcatgt
    63901 ttcagaagta caatccggtt atacgaaaaa tatccattca ttgttaaaag tcggacagcc
    63961 agtaacagtt cagatcatcg acattgatga atattccaaa aaaatcagtt tatctttaag
    64021 aacgttagaa aaaacaaatc cagctgttcc atatcgcaga aaaaggtatt tcacgaataa
    64081 aaatcgtaag atcggattta ccactattgc ggagcagtta cctatttgga tagaagaagc
    64141 attatctgaa ctagaacgga aagaaaataa gaaataaaaa gtgtattttt tctgaaaatg
    64201 tgctagaatt tttatgtaag ccatagaaca agttgatcga ggtggaaatt ttggcaagca
    64261 aaagagttgc tggtacaatt atgttgcatt tggaggatgg tactaaaaaa tttttggtcc
    64321 attcaattga tgacaagttg gaatttgcgt tagcggaact ttctgaagga aagactggtt
    64381 tagcgaatat acttaatttc ttaaaagaaa tagttcatat cgatgttagc aagattagtt
    64441 tgatggaatt gacaaataca catattaaag aggaaaatgt tccgttgttt gtctttgaaa
    64501 ctgaacaaaa gaatcaaaga gaagaattag gcgaaggata tatttgggaa gaaccaggtc
    64561 aaatgcgctc tgttcttgga acttacgaag tagagggagt gcctttcttc taaaatacag
    64621 attaagcgaa caaagaagtt tgaatttttt tcaaacttct ttttttattg tttggtccaa
    64681 aaaatacaat gaaatgttct gctaaagata gttttttagt gcattttatt ttcaaaatat
    64741 gttgaaaacg gttgtataac gaataataat aattgatcga aaaatcattt cacaaagtaa
    64801 tgcttaattt atagttgacc aaggaagaaa tacatgataa atttaacagc gttgattctg
    64861 aagtggatgt tatatcacat ttctaaaaaa tttaaaaaat agttattgac atgttactaa
    64921 cgacatgata agataactga gtcgttaaaa aagaaccact tgcgaagctt gattctatcg
    64981 aaaaaaactt caaaaaagtt cttgacaaat aacaaacgat
//
LOCUS       DBBGSP010000011        64324 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000011 DBBGSP010000000
VERSION     DBBGSP010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 64324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.011"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(150..2303)
                     /locus_tag="ACIZE9_000822"
     CDS             complement(150..2303)
                     /locus_tag="ACIZE9_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HGC6092705.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2698..3546)
                     /locus_tag="ACIZE9_000823"
     CDS             complement(2698..3546)
                     /locus_tag="ACIZE9_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC6092706.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3770..5710)
                     /gene="thrS"
                     /locus_tag="ACIZE9_000824"
     CDS             complement(3770..5710)
                     /gene="thrS"
                     /locus_tag="ACIZE9_000824"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGC6092707.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(6047..6226)
                     /locus_tag="ACIZE9_000825"
     CDS             complement(6047..6226)
                     /locus_tag="ACIZE9_000825"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HGC6092708.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6273..8096)
                     /locus_tag="ACIZE9_000826"
     CDS             complement(6273..8096)
                     /locus_tag="ACIZE9_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC6092709.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8374..10653
                     /gene="helD"
                     /locus_tag="ACIZE9_000827"
     CDS             8374..10653
                     /gene="helD"
                     /locus_tag="ACIZE9_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HGC6092710.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10746..11393)
                     /locus_tag="ACIZE9_000828"
     CDS             complement(10746..11393)
                     /locus_tag="ACIZE9_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092711.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11572..12291)
                     /locus_tag="ACIZE9_000829"
     CDS             complement(11572..12291)
                     /locus_tag="ACIZE9_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6092712.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12422..13573)
                     /locus_tag="ACIZE9_000830"
     CDS             complement(12422..13573)
                     /locus_tag="ACIZE9_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGC6092713.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13790..14530)
                     /locus_tag="ACIZE9_000831"
     CDS             complement(13790..14530)
                     /locus_tag="ACIZE9_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6092714.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14534..14857)
                     /gene="rsfS"
                     /locus_tag="ACIZE9_000832"
     CDS             complement(14534..14857)
                     /gene="rsfS"
                     /locus_tag="ACIZE9_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGC6092715.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14914..15507)
                     /gene="yqeK"
                     /locus_tag="ACIZE9_000833"
     CDS             complement(14914..15507)
                     /gene="yqeK"
                     /locus_tag="ACIZE9_000833"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGC6092716.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15491..16141)
                     /locus_tag="ACIZE9_000834"
     CDS             complement(15491..16141)
                     /locus_tag="ACIZE9_000834"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGC6092717.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16151..16462)
                     /gene="yhbY"
                     /locus_tag="ACIZE9_000835"
     CDS             complement(16151..16462)
                     /gene="yhbY"
                     /locus_tag="ACIZE9_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGC6092718.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16478..17587)
                     /gene="yqeH"
                     /locus_tag="ACIZE9_000836"
     CDS             complement(16478..17587)
                     /gene="yqeH"
                     /locus_tag="ACIZE9_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGC6092719.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17584..18111)
                     /locus_tag="ACIZE9_000837"
     CDS             complement(17584..18111)
                     /locus_tag="ACIZE9_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGC6092720.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18291..19076)
                     /locus_tag="ACIZE9_000838"
     CDS             complement(18291..19076)
                     /locus_tag="ACIZE9_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGC6092721.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(19069..19938)
                     /gene="accD"
                     /locus_tag="ACIZE9_000839"
     CDS             complement(19069..19938)
                     /gene="accD"
                     /locus_tag="ACIZE9_000839"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGC6092722.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19939..21318)
                     /locus_tag="ACIZE9_000840"
     CDS             complement(19939..21318)
                     /locus_tag="ACIZE9_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGC6092723.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21326..21745)
                     /gene="fabZ"
                     /locus_tag="ACIZE9_000841"
     CDS             complement(21326..21745)
                     /gene="fabZ"
                     /locus_tag="ACIZE9_000841"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGC6092724.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21770..22246)
                     /gene="accB"
                     /locus_tag="ACIZE9_000842"
     CDS             complement(21770..22246)
                     /gene="accB"
                     /locus_tag="ACIZE9_000842"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGC6092725.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22249..23484)
                     /gene="fabF"
                     /locus_tag="ACIZE9_000843"
     CDS             complement(22249..23484)
                     /gene="fabF"
                     /locus_tag="ACIZE9_000843"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGC6092726.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23503..24240)
                     /gene="fabG"
                     /locus_tag="ACIZE9_000844"
     CDS             complement(23503..24240)
                     /gene="fabG"
                     /locus_tag="ACIZE9_000844"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGC6092727.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24252..25169)
                     /gene="fabD"
                     /locus_tag="ACIZE9_000845"
     CDS             complement(24252..25169)
                     /gene="fabD"
                     /locus_tag="ACIZE9_000845"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGC6092728.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25276..25500)
                     /locus_tag="ACIZE9_000846"
     CDS             complement(25276..25500)
                     /locus_tag="ACIZE9_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGC6092729.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25553..26515)
                     /locus_tag="ACIZE9_000847"
     CDS             complement(25553..26515)
                     /locus_tag="ACIZE9_000847"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGC6092730.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26525..26965)
                     /locus_tag="ACIZE9_000848"
     CDS             complement(26525..26965)
                     /locus_tag="ACIZE9_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC6092731.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27271..28236
                     /locus_tag="ACIZE9_000849"
     CDS             27271..28236
                     /locus_tag="ACIZE9_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGC6092732.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28293..28523)
                     /locus_tag="ACIZE9_000850"
     CDS             complement(28293..28523)
                     /locus_tag="ACIZE9_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HGC6092733.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28609..29496)
                     /locus_tag="ACIZE9_000851"
     CDS             complement(28609..29496)
                     /locus_tag="ACIZE9_000851"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGC6092734.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29585..30808)
                     /locus_tag="ACIZE9_000852"
     CDS             complement(29585..30808)
                     /locus_tag="ACIZE9_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGC6092735.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30825..31871)
                     /locus_tag="ACIZE9_000853"
     CDS             complement(30825..31871)
                     /locus_tag="ACIZE9_000853"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGC6092736.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(32035..33762)
                     /gene="ptsP"
                     /locus_tag="ACIZE9_000854"
     CDS             complement(32035..33762)
                     /gene="ptsP"
                     /locus_tag="ACIZE9_000854"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGC6092737.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(33762..34028)
                     /locus_tag="ACIZE9_000855"
     CDS             complement(33762..34028)
                     /locus_tag="ACIZE9_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGC6092738.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34507..36741
                     /locus_tag="ACIZE9_000856"
     CDS             34507..36741
                     /locus_tag="ACIZE9_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6092739.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36889..37209
                     /locus_tag="ACIZE9_000857"
     CDS             36889..37209
                     /locus_tag="ACIZE9_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGC6092740.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37414..37638)
                     /locus_tag="ACIZE9_000858"
     CDS             complement(37414..37638)
                     /locus_tag="ACIZE9_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HGC6092741.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37836..39416)
                     /locus_tag="ACIZE9_000859"
     CDS             complement(37836..39416)
                     /locus_tag="ACIZE9_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGC6092742.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(39817..41193)
                     /locus_tag="ACIZE9_000860"
     CDS             complement(39817..41193)
                     /locus_tag="ACIZE9_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGC6092743.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(41321..42409)
                     /locus_tag="ACIZE9_000861"
     CDS             complement(41321..42409)
                     /locus_tag="ACIZE9_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC6092744.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            42581..43015
                     /locus_tag="ACIZE9_000862"
     CDS             42581..43015
                     /locus_tag="ACIZE9_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6092745.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(43093..43626)
                     /locus_tag="ACIZE9_000863"
     CDS             complement(43093..43626)
                     /locus_tag="ACIZE9_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGC6092746.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(43720..44898)
                     /gene="mutY"
                     /locus_tag="ACIZE9_000864"
     CDS             complement(43720..44898)
                     /gene="mutY"
                     /locus_tag="ACIZE9_000864"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGC6092747.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(44891..45688)
                     /gene="recX"
                     /locus_tag="ACIZE9_000865"
     CDS             complement(44891..45688)
                     /gene="recX"
                     /locus_tag="ACIZE9_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGC6092748.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            45795..47177
                     /gene="rlmD"
                     /locus_tag="ACIZE9_000866"
     CDS             45795..47177
                     /gene="rlmD"
                     /locus_tag="ACIZE9_000866"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGC6092749.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(47351..47929)
                     /locus_tag="ACIZE9_000867"
     CDS             complement(47351..47929)
                     /locus_tag="ACIZE9_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HGC6092750.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            48251..48721
                     /locus_tag="ACIZE9_000868"
     CDS             48251..48721
                     /locus_tag="ACIZE9_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HGC6092751.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(48829..50055)
                     /locus_tag="ACIZE9_000869"
     CDS             complement(48829..50055)
                     /locus_tag="ACIZE9_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGC6092752.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(50809..51009)
                     /locus_tag="ACIZE9_000870"
     CDS             complement(50809..51009)
                     /locus_tag="ACIZE9_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC6092753.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(51143..51751)
                     /locus_tag="ACIZE9_000871"
     CDS             complement(51143..51751)
                     /locus_tag="ACIZE9_000871"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HGC6092754.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(51836..52306)
                     /locus_tag="ACIZE9_000872"
     CDS             complement(51836..52306)
                     /locus_tag="ACIZE9_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGC6092755.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(52354..53268)
                     /locus_tag="ACIZE9_000873"
     CDS             complement(52354..53268)
                     /locus_tag="ACIZE9_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HGC6092756.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            53414..54217
                     /locus_tag="ACIZE9_000874"
     CDS             53414..54217
                     /locus_tag="ACIZE9_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGC6092757.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            54395..55342
                     /locus_tag="ACIZE9_000875"
     CDS             54395..55342
                     /locus_tag="ACIZE9_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HGC6092758.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(55410..55703)
                     /locus_tag="ACIZE9_000876"
     CDS             complement(55410..55703)
                     /locus_tag="ACIZE9_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HGC6092759.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYNPNLEEPTYHFKKQ"
     gene            complement(55731..56396)
                     /locus_tag="ACIZE9_000877"
     CDS             complement(55731..56396)
                     /locus_tag="ACIZE9_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGC6092760.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(56536..57168)
                     /locus_tag="ACIZE9_000878"
     CDS             complement(56536..57168)
                     /locus_tag="ACIZE9_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC6092761.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(57175..58242)
                     /gene="liaS"
                     /locus_tag="ACIZE9_000879"
     CDS             complement(57175..58242)
                     /gene="liaS"
                     /locus_tag="ACIZE9_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HGC6092762.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(58239..58970)
                     /gene="liaF"
                     /locus_tag="ACIZE9_000880"
     CDS             complement(58239..58970)
                     /gene="liaF"
                     /locus_tag="ACIZE9_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGC6092763.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(59139..59618)
                     /gene="greA"
                     /locus_tag="ACIZE9_000881"
     CDS             complement(59139..59618)
                     /gene="greA"
                     /locus_tag="ACIZE9_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGC6092764.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(59754..60929)
                     /gene="mltG"
                     /locus_tag="ACIZE9_000882"
     CDS             complement(59754..60929)
                     /gene="mltG"
                     /locus_tag="ACIZE9_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGC6092765.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            61133..62302
                     /locus_tag="ACIZE9_000883"
     CDS             61133..62302
                     /locus_tag="ACIZE9_000883"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGC6092766.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(62569..64203)
                     /locus_tag="ACIZE9_000884"
     CDS             complement(62569..64203)
                     /locus_tag="ACIZE9_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGC6092767.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT        18773 a        13391 c        10779 g        21381 t
ORIGIN      
        1 atttttgtca caaccttttt tgccgagtaa acggtgttca aaagccagtt tctcggtatg
       61 aagtcaaatt taagcaaaaa tgtgagaagc tattttcaca aaatttttct tcatactcga
      121 aactaagcgg ctttttcacg acctcttttt tattttgcca tgaacatatc ataatacgcg
      181 tccattattt ctttagcaat cgtcaagttt atgtggtctt gttcgtctaa taagttcggc
      241 aagacaacac tgatggcaat ttccggattg tctgttggtc cgtatgccac gatattacta
      301 ttgactgtcg caatatctgg atgaccttcc gcaaccgttt ctgcagtccc tgtttttgcg
      361 gaaaggtcca ttttcgcact ggctaatggt ttggctgttg tgtaaggatc ggtaccatgg
      421 acaacttggt ggaatccttc acggaggatc gccatatttt ctgcagaaat attgaccgta
      481 ttttctactg ttgtgccaat ttctttcttc acttcaccca agtttccatt ttcgtcattg
      541 ccatagatcg ctttgactag gtgcggctgt actcgtttcc cgccattagc gactgttgaa
      601 gcatattgag ctaattggat tggtgtatat gtgtcaaact gtccaaatgc caaatcggta
      661 aagttacctg gagcatacca ttctttgcca ttatccgcat tgaacttctt catataatca
      721 acagaacgtg agatcccagg agattcattc ggcaaatcga tcccagtcgt tgtaccaaga
      781 ccaaactctt tgaaagagtc tctcaattgc tgataagctt tagcttcttc atctaaacta
      841 ggtagtccca ttccaggtgt atagtctagt cctaacatct ttaacgccac tttgatcata
      901 tacgtattag aagacaattc cgatgctttg actgcatcaa gagcaacttg tccgcttcga
      961 ttaaagacag agcttttttc tgaagcacct tgcagacgaa tcggctcatc aatcaaaact
     1021 tgatttccgc tgatcgcgtt acttgcccag cctgctgtca aagtaccagc cttgactaca
     1081 gaccctggat caaaggcgct agtaatcgtg cctaaagcat tctcggtgat ttctttggaa
     1141 ccttgttcat gactgaaacc agtcattgct agcacttctc ctgtctgagg attcatagcc
     1201 actgcataag caccaggcga atactgtgct ttgccgttgt tgatcaatgt ttgataattc
     1261 cttttcaaaa tttcttctac ttttgattgg aattctgcat tcatagataa cattaaatta
     1321 gaaccttttt ccccagagaa gatttctttt tgattcgaaa catttccttc attatcaagg
     1381 gaaacttcat attgggtttt ggttccttgc aggacatctt catattgttt ttccaaataa
     1441 ctttgtccta cacggtcatt ccgagaataa ccttttgcta ggtatttctc tgcttcatct
     1501 gctggaagtc cttgcttttc agtcgtcaca ctgccaagaa tacttttcag tgaacttgct
     1561 gcattatatt ctcgtgtcca gtctgtgcca gtcgaaactc ctggaagttc agaagcgcgt
     1621 tctgccacaa cagctaactc ttgatcagta acaccagagt ttttgatata gacagtgttt
     1681 aattcatatg cactattcat ccgtttaaag atggtagcaa tttttaattg ctcctcgttt
     1741 aaattaatct catcagctgt gactttattg accatcgcac tatattgttc gctgttccct
     1801 aattgctttt cttttgccga aagtcttttt gtggcttctt tcaaatgttt gggatcagcc
     1861 agccaaaaat cttttttatc tctatctgtc agattttcat ctaccggaac atcgatcagc
     1921 gagttcagct tcgttgcgat ttcaagcaaa tctttagccg taacttgtgt tcctctcgta
     1981 tatgtgatgg cctgattcgc tttattcgta actaaagctt ttcctgtgga gtcgtagatc
     2041 attccgcgag gagtactttc ttggaccgta atcgtagaag tagacttcac tcgcgcctcc
     2101 atctcttcgc cgttcacgat ctgcaaataa cccaatctag caatcaacgc aacaaataac
     2161 gtaaatataa tgaaaaaaag aaaatttaag cgaaaaggaa catgggaccg gcgaaacgtt
     2221 ttgttcttag gttcttgtgc accttttctt attttttcta accaagaagt atttaatatt
     2281 tttttcataa aatctttcat catttcctat ccttccgcct atttacattc atgcttcatt
     2341 gtacccaaaa acttcttaat aaacaagaag tatttaatat ttttttcata aaatctttca
     2401 tcatttccta tccttccgcc tatttacatt catgcttcat tgtacccaaa aacttcttaa
     2461 taaaaaagaa aaaatgggcg gagcaagaaa ttctttacct aatttcaaga taaaatcaac
     2521 tttttgtttc acagcaatca cttaaagtta catatccaac tatttttttc attaaaaaat
     2581 aaacttattt ttgaaaatta tgttttctta agtcgtgaaa cactttgatg gatcatttat
     2641 ttgtggaaaa ctacgttttg ttattctaaa aaacttatat aaaaaatagt aaggttttta
     2701 tttcgaatcc ataaaatatt cttggattgc ttctcgtgtt tttttcactt tttcgctaag
     2761 cttttcgttt ttagccatat agaaataaaa aatgatatcg atcgtagcaa attgggccaa
     2821 aagtgaatta gttgccgcac ttcgattcgt gatttctttt ggtctagatg tttgtacgag
     2881 tacatcggct atcttgctaa gcgggttatt tccaaattgc gtcaacgcaa tgatttcgat
     2941 attcatgctt ttcgccagct cggctaatgc gactacatct gcacttctac ctgagtttga
     3001 aacaagccaa agcactttct ttttctcatt gctgacaagt tgcgggagca agacgtggat
     3061 atctttttca aaaatgattg gcttaccgac acgagaccat ttttgcagaa tatcttctac
     3121 tactaaagaa gaggcgccaa ccccatataa aaaaacagtc tctgccgatt ccaaacactc
     3181 tacgactttt tggatcgttt cttcttctag aatatctact gtttctttta tcgctacttg
     3241 tgcattgtta ccaagtttgt ttttgataga gtaaaaggac tcatttgctt ctatatcact
     3301 aaaaccttca tcgattccag tctgtagttc tgttgaaatc gtgattttga agtccgtcag
     3361 actttgaaaa ccgatttttt tggaaaaacg tacaactgtc ggcgcactca acccggaagc
     3421 ttctgctaat tcattagctg tcattgtagg gaccttctca atattaccga taatgtagtt
     3481 ggccaacttt ttttctgctg aagaataatc ttccatcata ctttcaatac gactaattac
     3541 gctcataagt tcctccaccc ttttaatgat agtctatgta agtataccat atcagaccct
     3601 tattcacggt cgtatactgg ataaaaaaca aaaaaacaat ccgcccaaca gaatatctta
     3661 tcccatcaat cccacagatt ctattgagca tctgtgtctt tgaggaatac ctgttatcta
     3721 ttgttcggat tgctttctat ctactacttt tttacaggaa atttacctat tagttttctc
     3781 tgctgtaatt tttgacttct gcttccatag catcaataaa gatattcaaa tcttctacag
     3841 ctgtttcttt acttccataa cgacgtacgt tcactgttgc atcttccaat tccttgtctc
     3901 caacaactaa ttggtaaggg atcttttgtg tttgagaggc acgtatctta tagcccattt
     3961 tttcattacg atcatcaact tctacacgca accccttcat ttgcaaacgt tctttgattt
     4021 cataagcata atcgccatgt gcatcaacag aaacagggat gattgttgct tgtataggtg
     4081 ccaaccatgt tggaaaagcg cctttgtata cttctgttaa ataagcgaca aaacgttcca
     4141 ttgtagaaac aattccgcgg tggataacta ctggacgatg cgtattttcc ccgtcttctc
     4201 caacatatgt caaatcaaag cgctctggca ataagaagtc taattgtata gttgataatg
     4261 tttcttctgt accaagagct gttttgactt gaacatctag ttttggtccg taaaaggctg
     4321 cctcgccttc tgcttcaaag taatctagtt ctaattcatc catagcggct ttcagcattg
     4381 cttgggcttt ttcccacatt gcgtcatcat caaaatattt atctgtattg tttggatcgc
     4441 gatagctcaa gcggaaacga taatctgtaa tattgaagtc agcatatact gccaccatca
     4501 attcaagcgt acgtttaaat tcatctttga tttgatcagg acgaacaaat gtatgaccat
     4561 cattcaacgt catttctcgt acacgttgta aacctgacaa agcacctgat ttttcatagc
     4621 gatgcatcat tcctaattca gcgatacgaa ttggtaattc acgataagaa tggatcgtgt
     4681 ttttgtagac catcatgtga tgagggcagt tcattgggcg aagaacaagc atttcgccat
     4741 ctcccatatc cattggcggg aacatgtctt cttgataatg atcccagtgt ccagatgttt
     4801 tgtacaactc aacatctccc attattggtg tatatacatg ttggtaacct agactaactt
     4861 ctttgtctac gatataacgt tcgatcgtgc gtcggattgt tgcccctttt ggaagccaga
     4921 atggcaaacc agaacctact tctggggaaa ccatgaacaa gtcaagttct tttcctagtt
     4981 tacgatggtc tctttctttt gcttcttcac ggagacggat atattctttc aaagctttct
     5041 tgtcaaaaaa ggctgtcccg tatacacgtt gcatcatttg attgtttgag tttccacgcc
     5101 aataagcacc tgccactgat aataatttaa atacttgtat acggccagtg gatggaacat
     5161 gtggtccacg acacaaatcg atgaattcgc cttgttgata agcagtaatc acttcttctt
     5221 ctggcaattc actaatcagt tctactttgt acggatcact tgcaaaaatt tctaatgctt
     5281 cctgttttga aagaacacgg cgttcgatcg gcagattttc tttgacgatt ttcatcattt
     5341 ctgcttcgat tgccggcaaa tcttctgcag ttacttggtt ttgtccatta tctgtatcgt
     5401 agtaaaaccc tgaatcgata gctggtccaa cgccaaagtg gatatttgga tagaggcgac
     5461 gcatggcttg ggccatcaaa tgagctgctg aatgacggac taagccaagt gcatcttcat
     5521 ggtctggtgt gatgatctca atacttgcat cttcctcgat tggacgagtc aaatcaacga
     5581 gttttccgtt cactttacca gctaaagctt tttttgctaa gctttttgaa atgctttcag
     5641 caattgccaa tgttgttgtt ccagactcaa attctttgac tgcaccatct ggaaaagtaa
     5701 tttttatcat aatagtttcc tccttgaaat gttttgattg atcagatcat caagctgaaa
     5761 aacaaaaaaa tcctagcatc tcttgaaaag agatactagg acgaaaagtt cgtggttcca
     5821 cctaatgttc aaacgcaaat gcgttcctca agcgttgtaa cggtccgacc gcccttgctt
     5881 caacaagggt ttcgaaagtg gtcatccttt ggttttctcc tggaaaagtt tcagcctagc
     5941 ttttcctctc ttatcgaaga ctctcaaatt cagttggctt tctcatcaat caattatgtg
     6001 tttatttaac cactaataaa tagaaaaatc aagtgggaaa ctaaacttat tttttccatt
     6061 ccccatttac accgtatgtt ccttttttca tctcattgat gatgacatgg atgtgttctt
     6121 ttggtgcctg cgtgttttta tgaacagctt ccgtgatatc tttcatcata ttttctaatt
     6181 gttccggact gcgaccttct actaattcga catgtacgaa tggcataatg ctctctcctc
     6241 tttctgatcg ttcttttttc aactcgattc tatcatacta tgtttgtctt gggtactgaa
     6301 tcaggaaaaa tggctggatc tttttttgct ctcaaggcac tcaaaataga gaccgtatcc
     6361 acgacttctt gcaaaacagc tccgaataat gcggggatta gtcccgtact tgcaattaac
     6421 atcaaaaaaa tacaaataaa gatgccaatc agtacagact gtttcgctat tctcatcgta
     6481 tctcttgaaa tcactactgc ttttgctaca cgcaagagat catctttcaa gatgaccgca
     6541 tctgcacttt cactagcagc tgtagaacca tgagccccca ttgcaatacc gatatctgca
     6601 gcagcaagtg ctggtgcgtc attcacgccg tctcctacca tcgcaacagg tctttgatct
     6661 ttagggatac tttctaaaat ggtcagttta tcttgaggca agctacgggc atgtacagaa
     6721 tctaattgga ctttttctgc aatcgtttga gcaatggcag atccatcccc ggtgatcatc
     6781 atcaaatttt tcacatcaag ttttcttagc tccttgattg tctttgctgc ttctgggcga
     6841 atctgatccg aaaataggat cgttcctgca aaagatcgat caattgttac atagattgct
     6901 gtattggacg tttctatttc ttcagctgaa acaaaagagg cacgtccaat ctttacttca
     6961 tgattattga ctactgcttg gattccttga ccggtcactt ctttcagttg actaacagga
     7021 tacagttggc tgtttttcac gttgttcact aacgaacgag ctaagatatg gctagattcc
     7081 tgttctgcac tagctgcata cagaagtagc tcttcttttt ttattccatt gactggctga
     7141 atcgcctcta cttccaatat ccctttggta agcgttcctg ttttatcaaa agcaatcgtt
     7201 tttgtacgtg cgagcttttc aatcgttgtt ccagttttta caacgatccc gtttttactt
     7261 gaacggctca ttcctgcaac taaagcaatg ggcgcagcta gaatcagtgg acaaggtgat
     7321 gccactacca gtacctcagc aaatcgtaaa gggtcttttg agaaccacca agaaatacca
     7381 ccgatcaaat aagcaatcaa cgtgaaaggg actgcataac gatcagctaa acggacaaat
     7441 cgggcaggct tttcttttga ttcttcgact agtttaataa tcatttgata ctggctgtct
     7501 gcggcacgtt tttcagcgat catttggatc gatccgtctc catttaaaga ccctgacata
     7561 atctgatctc caggtttctt ggtttccggg cgggactcac ctgtcaaaga agattcatcg
     7621 accgaagatt ctcctttggt cactcgacca tctgcgggta caagttcgcc aggcttgact
     7681 agtaactggt catcaatatt tatttcatcg attactatat cctgcaattt tccttctttg
     7741 aatcgatggg caattcttgg ggtgttatct aacaaagact gcagttcttt acccgctcgt
     7801 ttattcgcgt aatcctctag actatctccg cccgtaagca tgatcaatat catcaaacta
     7861 gcccagtatt ctttgacggc taatgttgca aggattgcgg taatcgctaa tacatctacg
     7921 ccatatcttc ctgaacgtaa cgtcttgatc atttccaaaa acatcaagaa ggcgagaatc
     7981 cctccagtaa atgcgacaat cgcaaatgca agggccggct ggtgaaaaac aaattcactt
     8041 aataaagcta tcccaccaat aagcaaagta agtaaaaatt ttttgaaatg tgtcattgtt
     8101 ttttctcctc ttttatgtga cttagagagg ttagtaataa atttccagct gcctctttca
     8161 tcttaagcat agtccttgac tagcactttt taaaacaata ggccttaatt gaaaacaact
     8221 atcactatca gcgtttccaa aattcatcag ttctacaaac aaaaatattc agcaaggatt
     8281 actttttcga ttcatcagtt aaaaagtacc ttttttcgaa aaactatgct atacttttaa
     8341 ttcgttattt acggcggaag gagcaaacat gcgatgaatg agaaacaact agaacaaacg
     8401 cacgtggatg aaacgatcga actaatccag atcgaacaaa atatgctgga tacaaaacaa
     8461 caagaattga ctcaggaaat gaatcattcg acaaaagaca cagctaatca caagattcga
     8521 gctggttcca atgaagcttt ttatgaatct gctgttgaat atcgccaaca tgagcaggaa
     8581 ttgcttttga aataccatac tcttgaagca cagcaaaaac gcctgcaaac gttgtctgtc
     8641 atgaaagata gtccttattt tgcccgtatc gactttaaag aagaccgtga aacagaaaca
     8701 ttatatctag gtatcgcttc tttaagagat ctggcagaag aaacaatcgt tattgactgg
     8761 cgcgcaccaa ttgccaatct ttattatgaa ggtgagattg gtcccgcatt ttatgaaact
     8821 gaaacagata gaatagatgt cgatctgcag ttgaaacgac aatttaaaat ccaagaagga
     8881 cgtattttat ctatggtaga tacgtcggaa gtaatcaatg atgacttttt gctagagata
     8941 ttggatgaat catcaagcaa ccatatgaaa aacatcgtct ctacgataca aaaagcacaa
     9001 aatgcaatca ttcgggacac aacaagtaaa gtaatgctga ttgaaggaat cgccggaagt
     9061 ggaaagacat ccgctttgct tcaacgtatt gcttttctgt tgtatcataa tcgcaagtgg
     9121 ctcgaggctg aaaacgttct tctattttca cccaaccatt tgttttctga ttacatctcg
     9181 actgtattgc cttcattagg tgaaagcggc gtgcctacac agacattcaa aaattatttg
     9241 gtgcagctgc tgccagagtt ttctttacta gatgaacagc aacaagaaag tggttttttg
     9301 ctaggggaaa aagatccgat acaagtgatg aaaagcggat tgaccttagt cgatcagatt
     9361 gatcgctata tccaaggcat cacaaactac ggtcccttgt tccgtgatat gaaaataaat
     9421 ggccgtacga tcctatcaaa ggaatcgatt cgccaatggt ataaagaaac aaatgaacaa
     9481 ttacctttac atcatagact ttctctatta caaacgaagc tcctgaaaaa attaggcggt
     9541 ctgcaaaaag acgaaacacg tcagcaatgg gtcaaagatc tggcggaaga acagctccaa
     9601 gaactatacg caacagatcc aaatcttgaa tatacagaac aaaaggagcg ttcattacgt
     9661 aaaaaactgg ccaaccaaat cgtacgtaaa agattccgtc gaatccatcg agggatcatg
     9721 aattatcaat ttgtcaatat aacgaaacaa tatctccact ttctacaaac tgtgccactt
     9781 tctcttctaa cacgacataa aatcagcgag accaggtggc aggaacattt gacaactgtt
     9841 cgtacacact tgcgtcaaag agaattgcgt caagaggatg ctgtactatt ctttttactg
     9901 atgcgccgaa catatccagt gacggttaca cacaaagctc gctatatctt tattgatgaa
     9961 atgcaggatt tcgcaccatc acaagtggca ttgctgcaag ccttgttccc aaaagcaaat
    10021 ttgactttct gtggagatct aaatcaaaat gtctttggaa atgaaacgat cgttggatca
    10081 ttggaagacc ttttcgtgga ccgtgaagtc actcgtttcc aattaacgac aagctatcgc
    10141 tccacaaaag aaatcactga ttttgctaat cattttattg tgaaagaaca tcaagtagaa
    10201 acaacagcaa gaaaaggaga ccttcctttg ctcatccaag gaacaacaga tgatatcaaa
    10261 ttgaattggt tagcagatac cattcgaacg actcagggaa aagcccggta ttggcgtaca
    10321 gcaatcatag ctaaaacaca agaagaatgc gaagctcttt atgctcaact gccagacgag
    10381 ttgaaacaac aagtccagct gattttaaat gagagtgact ttatgaagcg ttccattatt
    10441 ttacttccag cctttttagc aaaaggtctg gagtttgacc gagttttctt gtgggatgta
    10501 gatgcagaac atttttcttc tcagcaagac aaattgatcc tttacaccat gtgtacacgt
    10561 gcgatgcatg aattgaccct ttttacctcc aataatgaaa gtcctttgtt aaacaatatg
    10621 gatatttcat cttatgagaa aaaagtactg taagtaaaaa gacaactgct atcattaatg
    10681 ttagcagttg tctttttatt tacaataata attgcagaaa aagtaattca atcatttaag
    10741 gtcatttatt ctatatataa atccaaatct gtttcaggat attttaattt gacaagcgaa
    10801 ataatcattt tcagttcttc catgttttct ggatattctg ggtcaaatac cttgctatga
    10861 cggccaatcc cgccattgtc gatcaatcgg taaattcgat tccattcaat gaattggtca
    10921 attgattgga aattgctgat tggatagccg ccacaatcca aaatctctga tacacgaaat
    10981 gctaggtatg cactatcgat cactttattt tttttcgtgt ctatcttctc atttctttcg
    11041 ataagaattt tttcaggacg atgtttcaag ctccactcta atagtagaaa gaaagcctcc
    11101 atccgatact cttcttcaaa taaccgaaag gctgaatcag aacgacgaaa aagcagcgga
    11161 atcagataat tttgtctata aatcagcatt ggtgcgcggt ccaccataca ctctaaataa
    11221 cggttcagat accctgtacc gacatagttt cctaatcgat agccttcaac gccgaatctt
    11281 gcgtattttt gcgctaattt tgaacaatca gttacgttca cagctaactc ttctactttg
    11341 cggtaaccgc ttaagatacg ttcaaaaggt tctaaagtga tttttgcttc catattcttc
    11401 cccgtccatc ttccacatac ttcatatcat ttcacatgat acttatgctc tcatcatacc
    11461 acaggttgaa ttagaaaaga aaataaatca cacaaaaaag caagacaatc tgttagtgag
    11521 attgtcttgc ttttcgaaaa agactgaata cttttcgtta aaactggttg cttagtcttc
    11581 taatgccaca ttatggaaca catgctgtac atcttctaga tcttccagtg catcaatcat
    11641 tttttcaaat gtttcttgat cttctggaga tagtgttacc tcgttttgag ggatcatttg
    11701 gatctcagcg attgaaaaat cagtgattcc tttttctttt aatgcttctt gtatactatg
    11761 gaaatccgct acttcaccgt aaacgatgat ttgtccttct tcttccatta catcgcgaac
    11821 atcgatgtct ttttccatta ggtattcaag gatctcgtca gcgtcttctc ctgcaaaagc
    11881 aaagattgct gtattgtcaa acatgtaaga aaccgctccg gaaacaccca tgttcccgcc
    11941 atttttccca aatgctgccc gtacgtctgc tgctgttcga ttcacattgt tcgtcaatgt
    12001 atcaacaatc accattgagc cgcttggtcc aaatccttca tagcgcaatt cagagtatgt
    12061 ttcatctcct gcaccttttg ctttttcgat tgctcggtca ataatatgtt ttggtacatt
    12121 ataagtttta gcgcgatcaa tgacgaaacg tagtttttgg tttgcatgcg gatcaggatc
    12181 acctgatttt gctgccgcgt agatttcaat cccaaatttt gcataaatcc ggctattatt
    12241 agcatcttta gcagttttct ttgctacgat atttgcccat ttacgtccca tattttcact
    12301 tcgctttctg atttgatagt ttcataacgc aaaaacgtcc tgttccatta tacttgtgaa
    12361 tcacgattct gtgaagcttt ttttctttct tccttcattc ttctcatttt tagtcaatta
    12421 tctatactcg gattgggatt tgcccgaaat tctgttccgg aatattgcct cccaattgat
    12481 agatttgatc acttctaact aacagttccg cttcttgtgc ctcttttttt ccgattcggg
    12541 aataaataga aatctctttt ttttctttta agaatcttct tccagcatcg gtaaatccaa
    12601 gtagtcgaag ataattttta ttttgttgga caggaatctc ttgctttttg atattcagca
    12661 agacataaca agataatcgt tggatccgtg tccatgtata tctttttgtt tttacctttg
    12721 acacaaaatc ctcaaaacta tcagcagttg cagctgctgt tttcatgcgc gattctattc
    12781 cttcggtcat ctgatagata tctgtcagtt ccagcaaagt agaagataac aaccgataac
    12841 gcaaatacgg ccaataagat tcccaagtct gcagcgaaca agttgaaaga tcttcttctg
    12901 tctgaggcgg cacaagtcca gctattcttt ttccttcttc taacgcatgg cgaatggctg
    12961 ttgcactggc tatcctctga tctgtgatga ttttttcatg atagcctgca cttttacgtc
    13021 ggatcggatg taattccata gggtggacat acttggcatt ttcctttgca taacttaatc
    13081 ccaagatatg atttggcgaa gaaaaatcaa gcgtaatatc gggatacaga ctgcgaaaaa
    13141 cctcagtcat tttttgcgga taactatacg tttgatcaga cagttcttga aatgcctctt
    13201 ctatcctatc ttgattctct tggacaaagc gtccgaaact gctgtaatca aacgaagtct
    13261 cttcttctgt tccaaaacac aaactgtcac agtccagtgt ttgcaagatt tttactgcac
    13321 ctttagcaaa atagtcagct gactgaaccg cccattcgac gggaagctcc actactaaat
    13381 ccacaccatt ttgtaaagct tcattcgcgc gatgccattt atcgatgata gccggttcgc
    13441 ctctttgcaa aaaattcccg ctcattacag caatgacgac ctctgctcct gttatttttc
    13501 gtgccatttc cacatgatag cgatgtccat tgtgaaaagg attgtactct acgataatcc
    13561 cgcagctttt catgcgcatc ctccttcata gttatcgata aaaaagaaat agagacaagt
    13621 aaaaaaaggc aaaaatcgga aaaaataccc gaactatata aactattctc gcaaacacaa
    13681 tacttctgcg acgaaaagct gcactgcaag agcaatgcct atatcgttcg gatatataat
    13741 ttatgttgaa gatttattct tttcttgtta actcgagcag gcaaaaccgc tagtctttgt
    13801 atgctacaaa gaaccagcgc tttgatttct ctgatgctgc ttcgtctgta aaatcagaaa
    13861 atgcttcgac tttcgaaaag ccgctgtttt ccagcattct taaataactt tccaatggat
    13921 aggtacgctc ttgatgtagt tcatcttcac gaataaatcg accagaccct tcttgttctt
    13981 caacgaaaaa ggtaagaaaa tgttcgatgc tgtgtttctc gcttcctgga taactatccc
    14041 acaaaaaagc aaaattatcc ccttgataat gatagctata ttctggaaaa acctcatcta
    14101 cttgataggt ggagtgtacg tcaaataaaa atcggccatt ttcttctaac gcttgataga
    14161 cttcatcaaa cacttgctgt acctcttgtc tatttttcat atagcacagc gaatcagaaa
    14221 aacaggtaat tgcctgatat tgtccgattt ctgataaatc gagcatattg ccttccacaa
    14281 attggatcga tgcgtcttct tcatatgctc gctggctggc aatcatcaac atctcttctg
    14341 aaaggtctaa ccctgtcact ttatatccat cttttgcaaa ggcaaccgct aatgctccag
    14401 taccgcatgc cagttccaaa atattttttg tgtcttcttg taaatgacgt ttcgaaaaag
    14461 ctaaccattg ctgataaagt gtttcgtcca tcacttcatc gtaaatgaaa gcaaatgttt
    14521 cataagccat atgttaatcc aaccattcac taagatcgac tagcggagca tctgaccata
    14581 gtttttccag attatagaaa tttcgttctg gcgcatggaa aacatgtacg atcacatctc
    14641 caagatcgat caatacccat tttccgcctt cttttccttc aatacgtttt acttcatatt
    14701 tgttttcttc ttctttatca atgatttctt ctgtaattgc gttgatttga cgttcgctat
    14761 ttgctgaaca gatcatgaaa taatctgcca acaaggaaac atttcgaacg tctaaagcga
    14821 taatgtcttc tgcccgtttt gaatctgctg cttcaatcgc aatttttaat tgttctttac
    14881 tatctatgat gatttcctcc taatatgagc agcttatttt tttgctaccc agtaattata
    14941 tgtttcgatt gtttttggat aaatctgttg ttcttgcgca agcaaatggg ccaatgtatg
    15001 ttttgtttca aatgctacag cttcgtctag atcagcccat gcaatggctc gtgcatcttg
    15061 taccccagga aaatctcgac ctggttcaat atagtctgct acataaatga ttttgtcaag
    15121 gagactcatc ttagcagccc cagtcgtatg cacccggatt gcatgaagaa tctctgcatc
    15181 ggtgattcct aattcccgct ctacaaacga agcgccaaca agaccatgcc agattgcatt
    15241 attataattc aataactccg gatcaaaacc gtctcttacg attaccattt tgaactcctc
    15301 atctggtcgt tcttttgcat aatcatgtgt caatgcagca atactagctt tttcaggaga
    15361 agcaccgtat tttttggcaa gagccacggc tgtttcttct actccaagca catgcttgaa
    15421 gcgttgttcg ctcattctca tctgtatttt ttgcatcagg ttttctctag aataagcagt
    15481 atattcatta ctatagtcca tattcataca acccttcatt ttgaatataa tcaattactt
    15541 tatctggaac aaggtagcgg atagaacagc cttctttgat cttttgacgt attttcgtgg
    15601 aactgatgtc gatctcaggt acatctaccc aaattacagg atatggagta tccgttgtgt
    15661 atcctggtcg acgtataccc acaaagttga ccatagaagt cagctcatcg attttatacc
    15721 attttggcaa atattctacc atatccccac cgataataaa gtaataatct gtatccggat
    15781 tgttttgcgt caattccttc atagtatcat aggtgtaact tttcccacca cgagctaatt
    15841 caatcgtttc aatctgcaaa aaaggattgt cttccaccgc taattccaac atgttgagtc
    15901 gatgttttgc atcaatcgtc tgtttctcat caacatgagg tggctgataa gaaggcatca
    15961 aaaatacgcg gtcaagacct aaattccggc cagcttgttc agccatcact aaatgtgcaa
    16021 ggtgaacggg attgaatgtt ccgcccaaga tccctacttg ctttttcttc tctaagaatt
    16081 gaggcatttc ttcaggaaat aattgtgaac gaacaaatgt cttagcttgc gtattcatca
    16141 tggtcactcc ttatattgct tttacttctt ttgatagcct ttgatacttt tcttttgtgg
    16201 aaggtttgta taatacaata acacgtccaa tgatttggac gatttcgcaa tctatttctt
    16261 tttctaatac ttgagctgct tcttctgcaa tctcatctgt attttgaagt aacgatactt
    16321 tgatcagttc tcttttttct aaagcttctt caatttgaac gatcattgct gaattgatcc
    16381 caccttttcc gatttgaaaa atcggctgaa gatgatgcgc tttgctacgt aaaaaacgct
    16441 tttgttttcc tcttaaactc ataattttcc ttcttcctta aatcaatgct ttgcgtttca
    16501 atacatctac accctttggc gcccagcccg caattactac tggcgctgtt acagtgatcc
    16561 agcctagacc ggcaaaaacg atgtctgttt tttctttcac agaaaactca aaacgaacaa
    16621 gctccggaaa tgcctcgact tcatcaggac gaggaggctg taataatcca cctacatgtt
    16681 tttgataaaa ttcgtctgct ttttccagtt tcgttcgatg aatatttaca tcatttgaca
    16741 cataagcaat aaatgaagca cgattgccgc tgataaaatc aaatcttgca agtccgccca
    16801 agaaaagtgt ttgcccttca ttcagctgat aaactttagg tttgatttct tttaacggtg
    16861 caatgatccg caaatctttt ttacctaagt agtgcgccat ttgatggcga tggataattc
    16921 ccggtgtatc aatcaaaaaa tgcccgtcat ctaaaggaat ctcgatttta tccaaggtcg
    16981 ttcctggaaa ctgcgaagtt gtgattacat cttgtactcc cgctgtattt ttgatgattt
    17041 gattgataag cgtcgatttt ccgacatttg ttactccgac gatatagaca tcccgtccat
    17101 cgcggtattc ttcgattttt tctaatagtt ccgtcatctc atgagatttc ttagcactag
    17161 ttaataatac atctactgga cgaattcctg cttcgtaagc acgttccttc atccattgtg
    17221 ttaatttagt ttttttcaat gatttaggta atatatccac tttgttccca actaaaagta
    17281 ctggattgtc accgacaaaa cggtgtagtc ctgggattag tgaaccattg aagtcaaaaa
    17341 tatccaccac attgacgatc aatgcatctt tttgccctaa ttcattcagt aagcgcaaaa
    17401 agtcgtcatc cgtcaatgag acatcttggg tctcattata atggcgtaat ctgaaacaac
    17461 gctgacaata gacttccccg gaagctaaac ctttttccaa agccgtttgc ggcgtgtatc
    17521 ctaattcacc gggtttgttt gtttgtataa cggcaccaca gccgatacat tgtaattctt
    17581 ctgtcattcg attccacctc gccagcccat atcagggtgt tttgctaata gataggccat
    17641 aattcttttt tcccaaaaac gattaaattg tgtcttccaa ctatctgttg cgataatggg
    17701 ttttacaagg atgctacgta tccctgcacg attggctcca cgtatatcag tcataatctg
    17761 atcgcctacc attactatct catcatctgc taaatccaat tgtttctttg ctatgttgat
    17821 ccctcttgct aaaggtttca ttgctcgtgc aacatacaaa agatcaaatt tttcaatcgc
    17881 tcgcgcgaca cgttttgaat tattgtttga aacaacaaca acagggattc ctgcattttt
    17941 catttctaaa atccaagtaa gcaactcttc tgttccatct ggattattcc atgcaatcaa
    18001 cgtattgtct aaatcggtca atactgcttt gatgcctaga ttctttaatt gggcaggtgt
    18061 aatctgatag atggcttcta ccatccatgt tggtttgtaa tttgaaaaca tgctgtctcc
    18121 tcatctgcaa aaaatgaagg agcacataaa gtactcctca accccgtatt atactgcata
    18181 tcagcaaaaa aaactacctc tatactcgtt cgtctttcag aaaaagcatt tctttacaaa
    18241 atgaccaaaa ataaagattg atcacagaaa aatttagaaa caaaaaacaa ctaatattgg
    18301 cggaacctct tgtatcgttt ttccagtaat ttatgctgat ctaatcgaac aagttccgtc
    18361 aatctttcaa tcaacgcttt tttcataatg tgtgcgactt tatatcgtgg caactgctcg
    18421 ccgttgaacg tttcaggaat aactcgatca acgattccta actcgcgtag ttctggcgca
    18481 gtaattttca tcaactcagc tgcttctgcg gcgcgactac cgtctttcca caaaatcgac
    18541 gcaaatcctt ctggagaaag cacagcataa atcgtttctt ccagcatcca gacttcatcc
    18601 gctaaaccta gagcaagggc accgccactt ccaccttcac caatgatgat ggcgatgatc
    18661 ggtaccttta aatcagacat ttcgagcaga tttctggcaa tagcctctcc ttcgccgcgc
    18721 tcttctgctc ctacaccgca atatgcacct gctgtattga tcaaggtaat caccggtcta
    18781 ttgaactttt ccgcttgttt catcagtcgt aaagcttttc gatagccttc aggatgggga
    18841 gaaccaaaat ttctgcggat attttcctgc agatcccgtc ctttttgaat accgatcact
    18901 gttaccggtt tgccatctaa tcgagcgatt ccaccaacaa tcgcttcgtc atctgcaaat
    18961 aaacgatcac catggcattc ctcgaaagaa tcgaagatct cttcaaaaaa atccaagctt
    19021 gtccatcgtt ctttagctct tgctaactga acgacatcat gtgctgtctt atccacgatc
    19081 tatccatcct ttctgtgtat gcaattcaag aagcgtatgg attttctgtt tcaattccat
    19141 gcggggaaca atctgatcga caaaaccatg agataataag aattcagcct tttggaaatc
    19201 ttctggaagt tcctgcttga tcgtctgttc gatgacgcgt cttccagcaa aaccgatcaa
    19261 gctttggggt tctgctagaa taatatcgcc ttccattgca aaactggcag ttactcctcc
    19321 ggtcgtcggg tccgttaaaa cagttagata aaaaagacct tcattgctat gccgtttgac
    19381 agcagcagag atttttgcca tctgcattag agaaaagatt ccttcttgca tccgtgcgcc
    19441 acctgaagct gtgaacaaga cgactggaag actttccttt gttgctcgtt cgaataatct
    19501 ggtgatcttt tctccgacaa tcgttcccat acttcccatg ataaaattag gatccatcac
    19561 tccaataatg aagggaatcc cctgaatggt tgctttacca gtgaggactg cttcatgaag
    19621 tcctgtttta tcttgcattt ttttaatttt ttccgtatat tcgggaaatg ctagcggatc
    19681 tttggttaca agatccgtat cccattcttc aaaacttttt tcatcaataa tcaaagctag
    19741 acgctgccat gcaccgattc gaaaagcgta tccgcaatga gggcatactt tttcttcacc
    19801 gatgtctttc gtataaagga tatgtttgca atttggacac tttgcccaca tgttatcagg
    19861 aacagatggc gagttagcag gtttgctctc tctattagga ttgatccgaa tatatttctt
    19921 tttcttaaac agagccatct atgcgcctcc tatctccgtt tctggtgtcc aattcggtaa
    19981 aaattcttct tgtaaaaatg ctgtgctgta atcacctgct atgactgcag gatgactaat
    20041 caaatccatc tgaaattctg cgttcgtgat gattccttct gtgataaatt cacttaaggc
    20101 tcgctgcatc ttcattaatg cttcaaaacg cgtatttcca tggacgatta tttttgcaat
    20161 cattgaatca taatatggcg ggatcgtata tcccgggtaa actgcactgt ctactcgcag
    20221 tcccatccca cctgctggaa gcagtaagtt ttggatcttc cctggagaag gagcaaaatg
    20281 gaaagcagga ttttctgcat taatccggca ttcgattgcg tgtccttgga atactacttc
    20341 ttcttgacac acattcaaag gctcaccggc tgctatctcc acctgttttt ttactaaatc
    20401 gattcctgtg accatttctg ttactggatg ttccacttgg attcgagtat tcatttccat
    20461 gaaataaaaa tcgccttctt catccatcag aaactcgatc gttccggcat tttcataatt
    20521 gactgcttta gctgctcgaa cagcagcgtc tcctagtgct tctctttttg tttgtgagat
    20581 cactacagaa ggagattctt ccagtacttt ttgattgttg cgttgtaaag aacaatctcg
    20641 ctcgcctaaa tgaatgacat gaccaaatcg atcacctaag atctgaactt ctatatggcg
    20701 agcaggataa atgatttttt ccaaatacat atcatcattt ccaaatgccg ctgctgcttc
    20761 ttgctgagct gaagaaaaat gctgtgggag ctcttctttt gattgaactt tccgaatgcc
    20821 tttcccgcca ccacctgcag ctgctttcag catcactgga taaccaattc tgtctgctat
    20881 ttccaatgct tcttctactg tagataatac accagtactt cctggaatga ctgggacatt
    20941 tgcttcttgc atcaattgac gcgcattgat cttatttccc attgcatcga tcgttgcact
    21001 tttaggacca ataaatgtga tattgcactc ttcacacatg gaggcaaatc ggctattttc
    21061 agataaaaaa ccaaatcctg gatgaattgc ttcggctttt gtcacgattg cagcgctcag
    21121 tacttcctga acattcagat atgaatcaac ggcttttgcc gggccaatgc agattgcttc
    21181 atctgctaac tgtgtatgaa gtgcttcggc atctgcttct gaatatatcg ctacggtttg
    21241 gatccctagt tcgcggcatg cacgaatgat acgtacagcg atttcaccgc ggttagctat
    21301 caatacttta gaaaacatat ttcacctatc caatcataaa ggttaattcc gcttcggcta
    21361 cttttttacc gtctacttta gcgattcctt tgcctattcc ggctgaagct ttcactttca
    21421 atatctcaac ttcaaggtat aaggtatctc ccggtgtaac tttcttacgg aattttgctt
    21481 tgtccaatcc gccgaaataa gccgtctttc ccttgaattg ttcaagagaa agtaatgcaa
    21541 ctgctcctgc ttgagccatt gcttcaacaa tcaatacccc tggcataaca ggttcttctg
    21601 gaaaatgtcc ttgaaaaaag ggctcattga tcgttacatt tttcttagca acgatccgtt
    21661 ctccttcaac catttcttcc actcgatcaa tcaaaagcat tggataacga tgtggaatga
    21721 tttcttttat ttcttgtatg ttcattgttt tccctctttc ctgctttgct tatttttgct
    21781 gaatcctaaa gagtggctgt ccatattcga caactgactc gttttctaca aggatttctg
    21841 tgatcactcc gtcggcctca ctagttatct cattcatcag tttcatcgct tcaataatgc
    21901 agataacttc tcctttggca acttgatcac ctactttttt gaaagctggt ttgtcgggcg
    21961 ctggttgcag ataaacgatt cccacgattg gcgaaacaac ctcgattcca tcaaatactg
    22021 ccgattcttt ttctttcatt atttctggag cagttgttgc ttgttcaggt atgacattga
    22081 ctggctccga aactggcaac gtttcgtttg tttgaaccat attcatgcct cgacttgttt
    22141 tatttttatt catatacaat tcaaattgac cttcacgcaa atcgaattcc gttagcgagg
    22201 attgatcaaa ttgactgact aattctctga tttcattgat atccaaaatt attcctccca
    22261 gcgtttcatg cacagaaccg cattatgtcc gccaaaccct aatgaattac tcattgcata
    22321 agtaaaactt gcaggtttgc tttcgttttt gacaactgtc aagtcaatct caggatcttg
    22381 tttttctaca ttgatcgtag gtgggataaa ttgatgttct aatgccagca aagttgccaa
    22441 ggcttcgatc ccgccggctg ctcccaataa atgtccagtc atcgatttcg tgctgctgac
    22501 gtaagtatct ctgaaatttt cacctaatgc gatttggatt gcttttgctt ctgcctggtc
    22561 attggctggt gtacttgttc cgtgagcatt gatatatccg acttgttccg gctgtacacc
    22621 agcttcttcc atcgcaagct tcattgcttt agatgcacca gaaccatctg gagtaggagc
    22681 tgtcatatgg taagcgtcac agtttgcacc gtatccaacg atttctccat agattttggc
    22741 accgcgagct tgtgcatgtt ctaaagattc aagaactaga acgcctgctc cttcacccat
    22801 cacaaaacca ttccgatttt cgtcaaacgg aatcgaacca cgattaggat cagttgattc
    22861 tgagagtgct gttaaagctg caaatccagc aatccccatc tcacaaatcg ttgcttctgt
    22921 tcctccagca agaatgacat cagaatagcc atgtttgatg ttacggaatg cttccccaat
    22981 tgaattcgtt ccgctagcac aagctgttac gatagctgta caaatacctt ttgcacctac
    23041 acgcaaagca atatttccag ctgccatgtt ggcaatcgcc attggtacga acattggaga
    23101 aactcgtttt gcaccttttt catgtagacg aataacttgg ttttcgattg ttggaagacc
    23161 accgatccca gatccgatga tgacgccaaa ccggtcttga ttcatttttt ctttatctaa
    23221 accgctcatc tccattgctt ctaaagcagc gtagattcca tagatcgaaa acatatccat
    23281 tcgtttgcta tcttttttaa taaaatattt atcgtaaggg aaatctttga cttcacccgc
    23341 taaggtaatc cctgtttctg aagcatcaaa tttagtgatc ggtgcgatgc cattcgtccc
    23401 ctcttttaag ctattcaaaa agctgtctgc gtcatttcca ataggtgaag tgactccata
    23461 gccagtaatt accactcgat tcatttgttt gctctccttt tcttatccgt gcatgaccaa
    23521 tccgccatcg acattgatga cttgtccggt gatatatgga ttttgtgcta agaaaactgc
    23581 tgtttgtgca atatcttcta cttgtccgaa acgctgcatc ggaatttgct tttccgcttg
    23641 ttccttgact ttgtctgcta aaacttccgt catatcagtt gtgatgaatc ctggcgcaat
    23701 ggcattacat gtaatgcctc tagttgcagc ttctcgtgcc acagattttg ttaatcctac
    23761 tacgccagct ttactagctg cataatttgc ttgaccaata tttccaatca acccagatac
    23821 actagagaga ttaatgatgg ccccttctcg ctgcttcatc atttttttca atacgtgctg
    23881 cgtcatattg aaggttccaa tcaaattgat atccagacat tttttgaaat cttctgcatc
    23941 cattcgcatc acaagtttgt catttgtgat tccggcattg tttactaaca catggatcga
    24001 tccaagcttt tcttctgctt ctttgatcat ttgtcccgct ttctcataat cagagatgtc
    24061 accggaaact cctacgcatt ttacaccgaa tgcttcgatt tcttctatct tttcttttgg
    24121 aatctctccg cgaccattca aaatgatatt tgctccagct tttgcaaaag ctaaggccat
    24181 cgctttgccg attcctcttg tactacctgt gataaataca ttttttcctt ttacatccat
    24241 aacgttcctc cttatagtat tgctattgtt tcatcaaatg tctgcttatt ctcaacacgc
    24301 agaactggta ttgttttatc gatttttttc ataaatccgc ttaatacttt tccggggccg
    24361 acttcgatga cttgttcgat gccgattgtt tttaacttat ggatactctc atagaaacga
    24421 acaggttgca tgacttgctg ttcaagtagt cccgcgattg tttctttctt cattatttcc
    24481 gttgttgtgt tgcttatgat aggaaaagaa ggttcagaga attgaatctg acttaggtcc
    24541 ttcgccagtt tttttgctgc cggttctaaa atagctgtat gaaaaggccc gctgacattt
    24601 agagggatca ttcttttgaa ccctttttct tttaatagta aaacagcttc gtctactgct
    24661 ttttcttcgc caccaatcac gatctgctga ggtgtattat aatttgcagg agatacgatg
    24721 ccgtacttgc tagcttcatg acagctttcc tcgatcgttt caatcggcgc attcatcact
    24781 gcaaccattt tcccgcttcc agctggggca gcttctgtca tataagcgcc tctttttgct
    24841 actaacgcaa ctgcttcagt gaaggatagc gcattactag ctactaatgc cgaatattct
    24901 cctaaactca gtcctaaagc tgcatctggg atgattccat gctccttcaa taagcgataa
    24961 tacgcgatgc tgactgttag aatagctggc tgtgtatatt gcgtctgatc caaacgttca
    25021 ttttctgtaa agcaaagttc agccatatcg tagccgagaa tctcacttgc ttcatcaaat
    25081 gtctgcttta caacggcttc ttcatataaa tcttttccca taccttgata ttgtgcacct
    25141 tggccactaa ataagaatgc tgttttcatg tttttctcca atatatccag aatatatgtt
    25201 tgattcttcc tattcaaaaa ggccgagaca ttcctatttc aggaaatgtc ccagccccca
    25261 acctaatttt aatgattatg cagtttgttt ttctacgtaa gtcactaaat cttgaaccgt
    25321 tttgattccg tcttctgttt cgattttcac gtcaaattca tcttcaattt cattgatgat
    25381 ttggaataaa tccaagctgt cagcttctaa gtcttcttgg atgtcagtag tcaatttgat
    25441 ttcttcagtt tcttttccta attcttctgc gatgatttct tgaatttttt cgaataccat
    25501 aataatatat tcctccgata ttgtttgctt tttattttta taatttaaca gtctacaact
    25561 ccatgagaat acttccccat gttaaacctc cgccatagcc tgtaaatatt actttctgct
    25621 gttttcctaa ggtgatcttt ccactagaaa ctgcttcatc caataagata gggatgcttg
    25681 cagcagatgt attcccatat ttatccatat tggtcaggaa cttttcttgc ggcatcttta
    25741 cttttcgggc aattttctca ataattctga ggtttgcctg atgcaaaagc agataatcaa
    25801 ctggtttgtc tttcatgact tcttggatat tgtttgcaac gtctcgtacg gcaaaatcaa
    25861 aaatatctct gccagtcatt tgcaaataat acgaaccttc tgaatcttct gaatagaacg
    25921 gatttttatt ttgctggtag ccagcggtca atgagctact tctggtaccg tcagctgcta
    25981 atttttcttt cagcaatttt ttctgtggat tcgcttctaa gagaatccca cctgctccat
    26041 cgccaaacaa cacagcagtc gtacgatcag accaatcgat tagcttagat agtgtttcac
    26101 caccaatcac cagtccctta gttgagccgc agcggatcat tttttcagcc atgcttaacg
    26161 cataaacaaa tcctgagcac gcagcactga tatcaaaagc gatagcatga gttgctccca
    26221 atttcccttg tacttgtgct gctacagatg gtgtcgtgta atcgggcgac attgttgcta
    26281 ctaaaataaa atccaaatct ttagggttta gatttttctg ttttatcaat ttttccgcca
    26341 ctaaaatgca taaatcagaa gtctcctgat ttgttacaca tcttcgttca cgaatacccg
    26401 tccttgacga aatccattca tcagaggtat ccatcatctt ggaaagatca ttattagtaa
    26461 taatcttttc aggaaggacg ctggctgttg cagtaatcat tccaaattgt tccattaaat
    26521 atcctcactt atagtcttgc aagaagtcgt gcaagttttt cagtgcatcc agcaaggcat
    26581 gctgttcctc cgtagccatt ccgtctaaga tgttcttgac catttcacga tgaaaatgct
    26641 gatggacccg aaatagtaac tttccttttt tcgttagtcc caactttaca acgcggcggt
    26701 catcttcact gcggatacgt tcgacatagc ctttttttac taacttgtta atagcagtgg
    26761 tcaaggtccc aacagtaatt gatagttctt tggctacttc tgaagttgtt tttttcttgt
    26821 acatcccgat tgcctcgatc gtgtgcatct ctgtgattga cagatctttg aattgagatt
    26881 ttttcagctc agactcttcg attgtcaaaa tatcattgaa gacactaaca agataatcat
    26941 ttactgtttt taaatctggt tccatgttcc accgtccact aattagtttg attatcaaat
    27001 cttttgatgt tcaaactata tcttaacttt tttcaaaatg caaccttaaa agatcatttt
    27061 tttactatat gagctttttt taagatttta ctcatttaaa acaactgata aatcagcatt
    27121 tataatttct tttattagaa aaatcatcta tctcacatat tttgattatc aaagtatttt
    27181 ctgtgaacag aactatagaa ttccctaaaa cttgtccatt atttcaaaat ttgttatagt
    27241 ctttttattc aaagcgtaaa aggagatcct atgttaaaag aaaaaatgaa aactctcccc
    27301 atgctgccgg gtgtctatct tatgaaagac cgagatggta aggtcatcta tgttggtaaa
    27361 gcaaaacggc tcaaaaatag agtaagcagc tattttcatc agaataaaca gcattcaaaa
    27421 aaagtattac gtatgattca tcatataaca gattttgatt tcgtcgtagt agacacggaa
    27481 ttagatgctt tattgctcga gtgtcaattg atccaacatt accgtccttt ttataaccga
    27541 caaatgaatt atttcagtaa ttataattat gtacatatta ccaataaggg atttgtatta
    27601 acagatactc ctacggctcg aacatacggg ccttttcgtc tctataaaaa aatgccgtct
    27661 attttgcgta taatggaaga aacttatcaa atgccttggt tgtctgaaat tagtttgtta
    27721 gctttgcgag tccagcttcc tgacctacag gaaatgactt ttgaacagaa aaaaaaggaa
    27781 ctccaagggc tgtttcaagg ccgaaataaa aagctactga cttacttgaa aaaaagacaa
    27841 caacatttca tctatcagtt gaatttcgaa aaagccggta tgcttcaaaa agatatcgaa
    27901 ttagttactt attttattag acggatccag gaacaaaagc agtttttaag aacaccatcg
    27961 ctcaccttca gcatgccatt agcagcagat gagagtcaga aaaagcacta cctcgtttgt
    28021 tatggtcaac ttgcagaaac aatgattacc tctggtgacg tttctcctga cttctattat
    28081 gaaaagaaag aagctcattt atctttgaaa cgtcaattgt caaaagaaga aatcgatcct
    28141 gtacaaatct tgatcagtta ccgcaaaaaa ttagaaaaag aacagtttga aattgaactg
    28201 ttaaacaaaa aagaagctga aaagcaacta aattagttgc ttctcggctt cttttaggca
    28261 tcttcaactt caaatgtcaa ttatcctaaa atttattgga ttaagtcata gatttccatc
    28321 gctacgatat cgatattatc aaattcgtat tgctgatgag tatctgtttc agttaattca
    28381 aatgtatcgg tcgctttatc ataagttact gtacacttct ctacgccttc tttttcaaaa
    28441 cggcgaactt gcagttcatt atctgctgac tcgaccatag cctccagtcg ttttatgatt
    28501 gcgactaatt gtgaatgtgt catcggaggt cctccttttc ttatttctgt tatattgtat
    28561 caaaagcata gcctacttgc attgattttc tctaaaaaaa ctcgtttttt atgatttttt
    28621 ttctggtatt tttccttcag gccaccaaag tttgatcaaa gcttgggttc cgtcattctc
    28681 aaaaccttta tctgccaact cttcatatag tttcaatgct tgggtagttg ctggcaatac
    28741 aagatccatt ttttctgctt cttctaatgc aatctttaaa tctttgataa aatgtttgac
    28801 aaaaaaacca ggtgtgtaat cttcttttaa aatacgagga gaataattgc ttaaagacca
    28861 gttagctgca cttccacctg aaagcgtctc aatcactttc tttaaatcaa gtccgttttt
    28921 ttgtgcatag acaagcattt ccgtcattcc tgtcatcgta cctgcaatca tgatctgatt
    28981 agccattttt gtatgctgac ctttcccagc agaaccatgc aatgtaaatg tcgtaccaaa
    29041 ttctttgaat aaaggcagta cttgatcata aacggcttct tctccaccga ccatgatcgt
    29101 cagtgtacca ttctttgctc ctaagtcacc accggatacc ggtgcatcta acgcatctgc
    29161 gcctttttct tttgctgttt ttgcaatttt ttctgccagg cttggtgtac ttgtagtcaa
    29221 atcaactaaa atatgtcctg agatatctgc agaaaaaatc cccgactgtc catagtagat
    29281 ttcttctaca tctttggggt aacctaccat tgtaaagaga atattacttt gttctgctac
    29341 cgcttttggt gtatctgccc agatagctcc ttctgttact aaaggatcag cttttgcttt
    29401 tgtccgatta tagacagcta cttcgtgtcc tgcttctagt agatggcgtg cgacagcact
    29461 tcccatgacg cctgttccga taaaaccaag tttcattttt tcgacctcct aaaaatcaaa
    29521 aatccttgct tctatgctag tatacgctag aaacaaggat tttttcataa aaaatgtttg
    29581 aattttatct tttaaatgaa tttaatttta ttttgattcg ttcaatcgag tcttcttctt
    29641 cttttcttcg catctcttct tcatgataaa caaccatgtc ttgataaaat tcgatcatag
    29701 cttcgccgaa atgtgtagat gaaatatcat aaagtttagc ttctaaaact tttggatctt
    29761 taggaacttc actggaaata taatcaataa gtgctggtgc aaagtcttcg tcggtttcaa
    29821 aagttttccc taatgaagga tgatcgaaca atcggttcaa ataagcattt ccttccacga
    29881 cacaaggtgt tccggctgcc atcgcttctg tataagtaag cccttgtgtt tctgaagtag
    29941 aagcactgac aaaataatct gccgctttat aataaagtgc tacatcattg ttgtccactt
    30001 ctcctgtgaa ctgcacaaat tcttctaact gcagttctga gatcaattcc tctaactctt
    30061 ctacataagg tccttttcct acgataacta atctggcgtt aggataagcg gagatgacct
    30121 gaggaaaccc attaatcaag gcttggatat ttttctcata agaaatcctg cttaaagaaa
    30181 gaatcatcaa atggttttcc tgaagaccta gtgactccct taatttgctg atatcctgct
    30241 gagtgatatc agaacgtttg aatttttcaa tgtcgatacc agtaggaatc acgcgaagcg
    30301 gtgctattac accatagctg cgtaatgtat caataacacg ttcacttgga caaactacac
    30361 ctgtcgtatg atttgcaaat aatctagaca agtattttac atgggattgc ctgatcactt
    30421 ttcctttacc gatataatga aggtagtctt catacatcgt atggtaagta tggatcagag
    30481 gtattttcaa cttcttagct accatcttcc caagtatccc tgctccgaat tctgtatggg
    30541 tatgaataag atctagttct agttctttgg caaccaaata agcataccac atgcctctaa
    30601 caacaactct tcgatccttg aaagaaataa atggtacact tggcattcga atcacatctt
    30661 tttccaactt atccgcatta ggatcggtcg ttgtaaaaat atagacttca tgcccatgtc
    30721 tttctaattc ttgttttaat gttttgatcg atgtagcaac tccgctgact tgcggaaagt
    30781 aggtatcggt aaaaaagccg attttcatgt ttttcgcctc caaactagtc cttgacctga
    30841 tttacttttt ttaatttgct agagactttt tcattcagta cactttcgta tacattttta
    30901 agttcttcac cgattttatt gatacttcgc tcttttgctg tttgataacc ggcttgtgtc
    30961 gtactcggta gttcttgatt ggtaatctgt tggatcagtc ggataaattc ttcgtttgtc
    31021 ttccccatat agcagttctt gctatcttct aaccagccat tatacactgg aatatctcga
    31081 acaagtacgt tttgtttgct tgctaaagct tctaaaacaa cgatcccttc tgtctcttca
    31141 taagaaggga aaaagaatag atctgcacct gaatacgcac cttctatgat ctctccacga
    31201 atgtaaccag gaaacaggac attttcagga tgatcttctt ttacaatttt ccggatgttc
    31261 cgaggaatcg agtacatggg aacatgacca aaccaaataa atgtgtattc gggcatcttc
    31321 ttagcaattt ctacgaaatc aatgattcct ttacgttcga aaaacaaacc gacacaaatg
    31381 attacttttt gatccggaga cagtttgaaa tattctctga acttttgttc tttcattgga
    31441 tcagggtgat atttctctaa gtcgatccca ttggaaatag cttgaatcgg cacacggata
    31501 ccatagcttt ccaacaactg ttttgaataa ggtgttggcg tgatcagata gtccgctttt
    31561 tggtacaatc ctaccagata tttttttacg ataggagaaa gctggttcga tctgataaag
    31621 gaatttcgga aatcttcctc tgtagaatgc gcatgataga caactttttt tccttctctt
    31681 ctggctttat tgaccatatt atgactattg attccgtatg tattgatgtg caggatgtca
    31741 taatcttctt tttcatctag tgtataagag ataccgactt ccgtcagagc acgtttttga
    31801 tgatcaagcg cacgcccgat tccagatttt gcaagcatct tttcactttc aaaatataat
    31861 aataccttca ccttacgtcc cccttcactt atatagtata acatagccta caaactgtca
    31921 ctcaaactta agccctattt ttgtctattc ttactgacaa aaacgttttc ttaaaaaaga
    31981 acaaaaaaac tggcgtagct cttttacaag ccacaccagc ttttgatacg ttgtttattt
    32041 tacatattca tgaacaagtt caacgacttc ttccatcata tcgcattctt tcaatgcacg
    32101 atcagcaagt tcagccattt tcgctgtgtc caagcgtttc attaaactac gcgttttaag
    32161 aatagatgtc gcactcattg agaactcatc tagacccata cctactagca atggaacagc
    32221 tgtttgatct ccagccattt ctccacacat acctgcccat tttccttcag cgtgtgctgc
    32281 atcaattaca tttttgatca aacgtaaaat tgatgggtta tatggttggt acaagtaaga
    32341 aacgcgttcg ttcatacggt ctgctgccat tgtgtattga atcaaatcgt tcgtacctac
    32401 agagaagaaa tctacttctt ttgcaaactt gtctgctaag actgctgctg ctggaatctc
    32461 gatcatgatg ccgacttgga tcgtatcaga tacttccttg ccttcactta tcaatttttg
    32521 tttttcttct tcaaagatcg cttttgctgc gcggaattct ttgagtgtag ctaccatagg
    32581 gaacatgata cgtaaattac catgaacaga tgcacgaagc aatgcacgca tttgtgtacg
    32641 gaacatttcg tcgccttgtt cagataaact gatacgcaat gcacgatatc ctaagaatgg
    32701 attcatttca tgaggtaatt gcagatatgg tagttcttta tctccaccga tgtccattgt
    32761 acgaacaact acaggttttc cttccatacc ttctaataca gctttgtaag cttcatattg
    32821 gtcatcttct gttgggaagt ctggagaatc catatacagg aattcagtac ggtacagacc
    32881 aactgcttct ccaccattat tatggacacc aactagatct tttggtgttc cgatgtttgc
    32941 agctaattca aaatgcttgc cgtcagctgt gacagtttct gcatttttta atttttccca
    33001 ttctgctttt tgtgctgcgt aatctgcacc tgctttttca aattcagctt tttgttcatc
    33061 tgtaggatcg atgattacat cgccttcgat cccgttgaca gccaaaatat cgccttcttt
    33121 gactttagca gtaatttctt ttgtcccaac gattgctgga atttctaaag aacgtgccat
    33181 gatagcagaa tgtgaagtac gtccaccaat gtctgttaca aacgctttta caaaattgcg
    33241 atctaattgt gctgtatcac ttggagtcaa gtcatgtgca acaacgacca cttcttcgtt
    33301 gatcattgat ggatttggta aagtaacgcc taataagtgc gctaaaatac gtttagcaac
    33361 gtcacgaata tctgcagcac gctcttgcat ataagcatta tcttccattg cttcgaacat
    33421 accgatatac atatccgtta cttcttttag cgctgattca gcatttacgc tgttgtcttt
    33481 aatattttgc ttgatttgac ctaccatttc tggatctgaa agaaccatca aatgggcatc
    33541 aaatacttgc gcttctgctt cacctaagct ttgcgctgct ttttcacgaa tttgctgcaa
    33601 ttcttcagta gatttagcta atgcagcatc caaacgagct tcttcagccg cagtatcttc
    33661 tactgttgcc ttactgaatg ttaaatccgg ttgaactagc aggtaagctt ttgcaacggc
    33721 tacaccgtca ctagcggcaa tcccttttag catttcaacc attattcaga taagccttct
    33781 ttcttcattg tttcaacgat tgctgccatt gcatcagctt cgtcagcacc ttctgcagta
    33841 atagtaacat cagaaccttg acctacacct aaagacataa cgcccatgat tgatttcaag
    33901 tttactgatt tacctttata ctctaagttt acatcagagt taaatttgct tgctgtttgt
    33961 actaatagtg tagctggacg agcgtggatc ccagtttctg ctactacgtg aaattctttc
    34021 ttttccatat taatcggtct cctttaagtg agtgttgttt ttatgtgagg gttttctttt
    34081 ttagtaattc agagaatcct aacaaatgcc accctttcat ctgtaaagat taacattttt
    34141 tttcgttaga tacaacagtt ttcattcaat ttcagataaa agtattcaaa ttattccgga
    34201 ttctttttca tccttttctt cacattttat aacaaacgtg tttatttcct ttttcttgtc
    34261 gctttctctt ctcctgacgt ttatcattct ttcctttgac cctctttgtt ttcatatgaa
    34321 acgaattact tgcttccctt tttattttta gtataataag agtcaaaggt caggaatggt
    34381 caatagagat ttcacctttt ctacctcata aatctcttaa aaaactaggg gttattcttt
    34441 tacctcatga aaaacgagat gtaaaatatg gatgtaccca tttttgtgaa aggacgtgaa
    34501 tgattcatgc tttgtcaaaa ctgcggcaag aatgaggcaa cgattcactt gtatgccact
    34561 gtcaatggtc agcggacaca actcgattac tgtcagagct gttatcaaaa aatcaaaaat
    34621 caacaaaatg gaggtctgac taatatggcc caaaatgatc catttggatt tggcagtttg
    34681 gacgatcttt tccgttccat gtctcgccaa atgcaacagc aaggaaatta tgagcaaaca
    34741 ccaccaacac aatttggcgg aaacaacaac ttcaatggtg gtcagccacc tcaaggcaat
    34801 acagaaggtt tattgggaga atacggaatc aatatcacag aacaagcacg acaaggtgat
    34861 atcgatcctg tgatcggacg cgatgacgaa atcaaacgag tcattgaaat tttaaatcgc
    34921 cgaaccaaga acaatcctgt cttgattgga gaaccaggtg ttggtaaaac agcagttgtt
    34981 gaaggtttag cacaaaaaat cgtagatggt gatgtaccgc aaaaattaat ggacaaagaa
    35041 gtcattcgtt tagatgtcgt atctttagtc caaggtactg gtatacgagg acaatttgaa
    35101 gaacgtatgc aaaaattgat tgaagagatc cgtcaagcag aaaatgtgat cctattcata
    35161 gatgaagttc acgaaatcgt cggtgctggt tctgctggtg atggaaatat ggatgctggt
    35221 aatattttaa aaccagcttt agctcgagga gaattgcaaa tggttggtgc tactacctta
    35281 aatgagtacc gcatcatcga aaaagacgct gctttagaac gtcgtatgca acctgtacgg
    35341 gtagatgaac caactgtcga agaaacgatc agtattttga aaggtttgca aaaacgttat
    35401 gaagactatc atcatgtaaa atatactgat gaggccatcg aagcagccgc aactttatcc
    35461 aatcgttacg tccaagatcg cttcttgccg gataaagcca tcgatttgct agatgaaaca
    35521 ggttctaaga aaaacttgac gatccaaatc gttgatccta aaacaatcga gaaaaaactg
    35581 caagaagcag aagaacaaaa agttttagct tctcgagaag aagatttcga aaaagcagct
    35641 tattatcgcg atcagatcaa taaacttcaa aaaatgaaag aacgtcagct cactgaagag
    35701 gaaacacctg tgattaccga aaaagatatg gaaaaaatcg ttgaacaacg gacaggtatt
    35761 ccagtgggtg aattaaaaga aaaagaacag acacaactga aaaacttagc agatgacttg
    35821 aaagctcatg tcatcggaca agataacgct gtagatcgag tagcgaaagc gattcgccga
    35881 aaccgtgttg gattaaacaa acagaatcgt ccaatcggct ccttcttatt tgttggacca
    35941 actggtgtag gtaaaacaga gcttgcgaaa caacttgcct acgaactatt cggttcacaa
    36001 gattcaatga ttcgtttcga tatgtctgaa tatatggaaa aacatagtgt ctctaaattg
    36061 attggttctc ctccaggtta tgtcggatac gaagaagctg gtcaattaac agaaaaagta
    36121 cggagaaatc cttacagtct tgtcttgtta gatgaagtag aaaaagctca tccagatgtt
    36181 ttgcatatgt tcttgcaaat cttagatgat ggtcgattga cagatgcaca aggaagaacg
    36241 gtcagcttta aagatacgat catcattatg acaagtaatg ccggaactgg taaagtagaa
    36301 gcaaacgttg gttttggtgc ggcacgcgaa ggtgttactc gttctgtatt gaaccaatta
    36361 aacaactact ttacaccaga atttctgaac cgttttgacg ggatcatcga attcagtgca
    36421 ttatcaaaag aaaacttgat gacaatcgtc acactaatgc tagacgatgt caaccaaatg
    36481 ctggcagcac agcaacttca catcgaagtt cctacgaatg tcaaagaaaa attagttgac
    36541 ttaggctatg atccatctat gggtgctcgt cctcttcgac gcacgatcca agaacaaatc
    36601 gaagatggta tcgctgaatt ttatcttgat cacccttcta tccatgagtt gaaagcaaaa
    36661 ctggataaag atggaaaaat catcgttact tctaaaccag aacgtttggc taaagaatca
    36721 gccgaagaaa cggctgaata aatccagttt tatagcgtga gacggtattt ctttgagaaa
    36781 tgccgtctca ttcttttttc agaaaagtca aaatactgtt cattttataa aaaagaaatt
    36841 ataataagag aaacaagcaa ttaaaaatac ataaaagagg tgagcgccat gaaattggta
    36901 aatgtaacaa acagccattc ccgtcttgta ttaaaccagc ttgaaaacac tgatgcccat
    36961 ctagtcaagg tctacacagc cggaaatacc actattgtct acactgaagc ccctgaacat
    37021 aatgaaattc tgctgatcaa tgacaaacgt aaaatccagc cgaaagaaat cgaagatgct
    37081 aaaaattatt tcttagataa aatcaaagac gccgtttacc acgaggatga aatcaaagta
    37141 atcgaattgg caggccttgt tgaaatctcg attccaaaac atgaattagg cgctacatta
    37201 gccgtgtaaa caaattttga acataataat taaagagcgt gggacaaaag taaagaacac
    37261 ttttgtctca cgctctaaac acgtataaac ggcgaaagca gaagcaactc cttcggaaat
    37321 aagctgaaat tcacgaaaat tgcttttcaa atttttgtga attccagctt atttcttgga
    37381 gttaaacgct tctgtctcag cctctttttc tttctagctt tttgattttt ctcttttctt
    37441 ttgtactttt ctcttttcat tttcagttct acgcgtgtct ttatttttaa ctttttcctc
    37501 tttatggatg attgatcgta ctttttgtgc aatttgctcg tttttgtccc agtcttttac
    37561 atctaataat cgacataatc gtaacatctc ttcttttttc tgtttttttc tttcacgtct
    37621 ttgccattct gtttccatgt gtcacactct cctttcttta atcatatgta cgcaaaataa
    37681 tttttatatt tttttgatta gacatttcta tgattttaat atagtaaaaa gagccgtcac
    37741 ggaaaatccg tcacggctct aaacaaaata tgagaggctg tttttgtttg gctattctta
    37801 ttacttgatg cagggcagct tgtgtcaaga cttctttaca tcaaactttt taattttaca
    37861 ttgggatatt tatccgcaaa ccagcgttct gcaaattggt tctcgaataa gaacaacggt
    37921 tggtcgaaac ggtcacgagc caagatattg cgacttgaac tcatcttctc atccaaatct
    37981 tctggatcga tccagcgagc gattttgtgt cccattggag acatgattac ttcggcgtta
    38041 tactcattta acatacgata ttggaatact tcgaattgta gctgaccaac agctccaatg
    38101 atatattctt ccgttagata tgttttataa agctgaatcg ctccttcttg aactaattga
    38161 tagattcctt tgtggaagga tttttgtttc atgacatttt ttgcagtcac tttcataaac
    38221 agctctggag taaatgaagg gagttcttca taagcaactt ttagttttcc ttcgaacaat
    38281 gtatccccaa tctgataatt gcctgtatca tatacaccga tgatatcgcc tgctactgct
    38341 ttttcgacgt tttctctcga atctgccata aattgtgtga cattgcttaa tttcagtttt
    38401 ttatttgtac gttccaacca gacatccatt cctcgttcga atgttccaga acagattcgg
    38461 acaaaagcga ttcggtcacg atgggctgga ttcatatttg cttggatctt gaatacgaaa
    38521 cctgaaaatt cttcctcata aggacttacc atctgatcat cttgtgtttt gtgtccataa
    38581 ggagctggtg ccaattcaac gaaagtctct aaaaaagtct gtacaccgaa gttagtcaat
    38641 gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa ttttttcttg attaaatgca
    38701 tctccagcct ctttgattag ttctacttct tctaagactt gttcatataa ggaattttca
    38761 gttagaggat gattttcggg aagcagtcca tcttcatcca attctactaa tcgttcatcc
    38821 tgataatttt ccggacgata aaactctaca cgattatggt agatatcata aagaccttct
    38881 agccctttac ccataccgat tggccaattc atcggataag attcgatatc taatagctct
    38941 tctaattctt ctaacaattc caatggttca cgaccatcac gatctagttt gttgataaaa
    39001 gtaaatatcg ggatgccacg tttttttaca acttggaata atttctttgt ctgtgcttcg
    39061 atcccttttg cactatcgat taccatgacc gcactatcca cggccatcaa agtacgataa
    39121 gtatcttcag aaaaatcttc atgtcctggt gtatccaaga tatttactcg tttcccttga
    39181 taatcaaact gcataacaga actagtaaca gaaatcccac gttgtttctc gatttccatc
    39241 cagtctgatt tggcaaaatt acctgttttt ttgcctttta cggtcccggc ttgacggata
    39301 gccccaccaa acaatagtaa ttgttctgta atcgttgttt tcccagcatc cggatgggaa
    39361 atgatcgcaa aagttctgcg attgtccact tgttgcttta attttggatt attcataacc
    39421 taactccatt tcttccattc aattatttat attttctcta ggcacagatt gtccgatctc
    39481 ttaaagaaag acaatttcat atagggctgt gacaaaagcc gtgtagcagt ctctttttcc
    39541 gagtaaacgg cgttctagag acagcctatc agcaataagc ccacccaagc caaaaatacg
    39601 aaaagctgtt tttgcttggc tgctcttatt acttaatgca ggatagcttt ttcacaacct
    39661 ttgtcaacta ctacaactga atcagtatag catggattca gcgaatgaaa aagccaccaa
    39721 accataagag tcaaatattt ttttgtcagc tgactaaaag aaaagacgtg ttgcttgttt
    39781 attcaagcaa cacgtctttc ataaccaagt ttccaattat cttcttggct cgtcatcttc
    39841 gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc gcttctgttt cttccggatc
    39901 atgaaaaatg acacggattt taaggattcg agaaccttcc atttcttcag aaaccagcgt
    39961 aatattatcg acatcaaacg ataacttttc gccttcatcc ggaatcatgc ctaatgctgt
    40021 aatcaaataa ccagccatcg tatctacatc actcatatgc agatcactgt caaaagcttc
    40081 attgaactca tcaatcagca tacgtccttg gatgatatat tcgtgttcat cgattttttc
    40141 ataaagattc tcaacttcat ctgattcatc atcgatttct ccgacgattt cttctaaaag
    40201 gtcttctagt gttgctaacc caacgacgcc gccatattca tctaataaaa tagccatctg
    40261 attctgcgtc tttttcattt catataacag atcatcaata aagaccgttt caggaacgaa
    40321 taaaggctcc tgcatgattt tcttgatatc taaattatca aagccgaatt tatgggcagc
    40381 ttttagtaaa ttctttgtat gaaggattcc gactacttta tctttgtctt cgttataaac
    40441 agggattctt gaatagtttt cggataaaac ttcattcaca ttttcttcca cagtgtcgtt
    40501 gatatcaatc ataaatgcat ccgttcgtgg gaccatgact tctcgggcaa ctttcgtatc
    40561 aagagaaaaa accccttgga gcatttctaa ttcttcatta ttcaatacgc cttcgttttc
    40621 aagcatataa cgcatttcat ctctggtcat ttttgaatct tcatcatcaa aagtcatcgg
    40681 cgtgatacgc gccaataaac ttgtggaagc agaaagcagc cagacgaagg gcttagctac
    40741 tacaccaatc aagcgtatca gccctgaagt gaactttgcg acttcttctg atttatttaa
    40801 agcaatacgt ttagggtaca attctccaaa aacaatcgat acataggtca aaatagccag
    40861 cacaatgata tttgcaatat tttttgccgc tgtgccgcca cctaataccg gagctaaccg
    40921 ttccgataaa gtattagcta gtgaagcacc agacaaaatg ttgaccaaag tgattcctac
    40981 ttggattgtc gataggaaat tatttggatt ctgcaatatt tttaaaagct tttgagattt
    41041 cacatctcct tcatcagctt tttgctcgat tcgattctta ttgatcgaaa caacagcaat
    41101 ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg atcaataata aaatctgcgc
    41161 taacagcgac tgactctcag ggtcagcatt cataatcgca ttctctcctt ataaaattaa
    41221 tttttagttt acgatagaaa aaaacgtggc actatagcca cgttaaaatg gtatcacaaa
    41281 gcaattttct ttgcaataaa aacaagtgta ctaaaactac ctacgaggtc gtagcaattt
    41341 tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt gattatatag gaaatgatcg
    41401 tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc aagcaatccg gcaatatttc
    41461 cagctactag aagaacgata atgatcgtta atggatggat tttcagtgat ttcccaatta
    41521 cattaggata aatgatattc ccatccaact gttggacgat tagcacaacc acacaacaaa
    41581 gtaatgcttt taccggatca ttgaagactg ttactagaaa tgcaggtgct agtcctagat
    41641 aaggtcctaa atatggaatt aggtttgtca atcccgcaat gaccccaaat aagaaagcat
    41701 aatccacacc aattaccata tatcctaaaa atgtgaaggt accaacgaat aaacattcga
    41761 ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag ttgccccaat aactccacaa
    41821 tttggtttct tcttttttct gggaaaaact gttggatgtt tggcactagt ttttctccgt
    41881 ctttcaacat atagaacaag atgaatggtg ctgtaatgat tactacggtt gccgaagcga
    41941 tcgttccaac gatcgaacct aaactattgg atactccact aaggaattgc tgaatgattg
    42001 tcccgtaaga aatgtctaat tgctcaaaat atttattgat atctacttcc ttgaacaaag
    42061 gcaattcggc tacctctttt aaccagcttt ctacctgttt gatgaaatca ggcatattag
    42121 atgccaatga ggaaatttgc tgtactagac ttgggatgac actaagtaaa atccaaataa
    42181 ttgctgcaac taaaaggagc agcacaattg cgacagccca tattcttttg atttttgctt
    42241 tcatcaacag cttgacaata ggattcaata aatagtaaag aaagcctgca atcagtacag
    42301 gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa aataaagttt atttctgatg
    42361 aaatcatgat caatgcagct atgatcaata attcaagcga ccaaaacatt agtttagact
    42421 gtctaagttt ttcaaacaat agatttcctc ctttctttct tactagtata tattatattc
    42481 gttaaaaatt cttttattct ttttttattt ttgaaaactt gccatacttt ttatttgttt
    42541 tattttccag tatactatac gaaaggaagg tggctagacc atgaaagttg tacaaacaaa
    42601 agatacaatg agcaatattt acttagatgc tgtacggatc aggcatcaag tttttgtagt
    42661 cgaacagggt gtgcctttgt ctcgagaaat agacaaagat gaagcccatt gtatccactt
    42721 cgtcctgtac tcagataaaa aagaaccgca aggaactgta cgtcttttgc ctttagaaaa
    42781 cggaaaaatg aaattacagc ggatggcgat tctttctgaa tacagacacc aagggttagg
    42841 aaaaatattg attgaagaag cagaaaactt tgctaagaat caaggctata atacgatttt
    42901 attaggggca cagtccacag ctgaaacttt ttacgaaaaa ctaggatata cagcttacgg
    42961 cgatcctttt gaagatgctg gcatgcctca tatttatatg aaaaagactt tataaaaatt
    43021 tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa atctctcact ggcttactgt
    43081 tcttttttgt gtttacttac gcgacaattg cttgtaacgg ttataccaaa tatcaatata
    43141 gccttccgag aacgggccat ctccattatt gatccagtca accagaatct tcacattttc
    43201 ttttaggatg aagtcaatat cgttcgggta attcatcatt ttgctgtgca tctcatattc
    43261 atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc ttgatatcca agtcatagtc
    43321 gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa gctagattac aataatagga
    43381 aacccccttt tctctgatca ttgctattac attgaaccag tattttttat gaaaataaac
    43441 aatcgctggt tcgcgcgtta cccatcggcg tccatcagat tcagtgacta atgtgtgatc
    43501 attcacgccg atcatagagt gttcgcttgt ttttaatacc atggtatctc gccacgttcg
    43561 atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca aactctcctt cttttggaac
    43621 tcccatagca acccttcctt aagcagcatt ttgtgctttg tgtttgggtg ttcattacac
    43681 cgacatcata attattatat caataaaaat gagctttgcc tagaaaggat tcctattgtt
    43741 tcgatttttc tctaactgat ctaccagttt catttggacc ttaggaaaaa cgaccgaatc
    43801 aaatgcatca ggcttcaacc acttcgaagt tttgttctcg gtaaattctt gttctgctcc
    43861 ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc agatgactaa aaatatgagt
    43921 aacttctcct aaatgtcgtg tctgccaaac aaagagttcc tgcttttcaa atgggagatt
    43981 ttgctcttct tctgctacta ggtcatcaaa cagatcgatt tctggctttg tttcccattc
    44041 ttttttcaat cgctcatact cctcttgtgt cacttccatc attggaaatg tccacatatt
    44101 cgccagcaat ttttggctat ctctttcttc aaaataatac gctccagaat gattttgaag
    44161 agctgcactg atataataaa cgtcttttgg ctttgctttt tttgttttta caggaaaact
    44221 cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg atcggacaag tctcacactt
    44281 tggagaagtt ggtgtacaga tagctgaacc tagatccatc attgcttggt tgaattcacc
    44341 tggatgcttt tcatcaatga ttttccgcat cgcttcatca aagattttcc tgctagaagc
    44401 ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact actcgcatca cgttgccgtc
    44461 aactgcaggt tctggaagtc caaatgcgat acttgcaatc gcgcctgtcg tatatggtcc
    44521 tattcccttc aatgagctaa tttcttcagg cgtttgcggc atttccccat caaattctga
    44581 catgatctgt ttagcagcag cttggatgtt ccgggctctt gagtaataac caaggccctc
    44641 ccatgctttt aaaagctttt cttctggagc atttgctagc tcttcaattg taggaaacca
    44701 ttccatgaaa cgataaaaat aatcgatcac tgtgtctact ctggtttgct gaagcatgat
    44761 ctcagagatc cagatacgat aaggatcacg attatagcgc caaggcaggt ttcttttttc
    44821 ttgttcatac cattgaatga actgatcttg aaattctttt gtttctttat ctgtccattt
    44881 ttcccattct ttattcactt tcctcttcct tttccgtaat gaatcgctgg atcatatcca
    44941 aatcaaatcc tttttgatat aagctttgct ttacttttag atttcttttt ttaggttcaa
    45001 accttaaatt tcttcgccat agtttatctc cttgtttgac taaataatca tattctattt
    45061 cttgatctgc ttcttgcgga agatcagcta tcgcttgttg gatcacttct tgagaaaagc
    45121 ctttcgtcat caatgtttgt tggatttttc tcaataattc tttttggctt tttccgtgat
    45181 tttttccaaa cgctttttcg gctgtctgat gtgcattttg aacttggtct tcaaatgtat
    45241 attggctgag cgcttgttca atgatttcag gtttcaaacc tttttgctgc atctgctgcg
    45301 ctaatttctt tggtcctttg tcacttaagc gcatattcgt gcgcacataa ctttccccat
    45361 agaccaaatc atcgacaagg tccaattctt ttaagcgggc tacgatttta tttcgatctt
    45421 cttgaaggat ttccttttct tttaagtatg ttcggatttc tttttccgat cgcaactgat
    45481 aacttaagta attcattgct aggtgaaaac cgaaatcagc tccgctactc ttcttgatct
    45541 cttggatagt ttcttcgtct aattcccgtc cttttaataa tcgatagcgt actaatacat
    45601 cttcagatac ttgtaaagct tctccttcag ataaatctac gcgatagaaa gggcctttgc
    45661 ctttactgat tctcgtaacg gttaacataa acatcctcct cgaacatata ttctctatca
    45721 taccacagaa aatccccgta atcaggtatt atatgttaga ataaaccaca gaaaaaagaa
    45781 aaagggagat acttatggca gaaacaattg tcaaaactgg acaaacggtt cctttgaaaa
    45841 tcaagcgttt aggcataaat ggtgaaggaa tcggttattt caaacggttg atcatatttg
    45901 ttccatatgc actaccaaaa gaagaagtac tagtgaaaat cacgaaagca actcctcgct
    45961 atgcagaagg agaattaata aaagtcaaaa aaacaagcaa agatcgcgta gtggcaccat
    46021 gtcctgttta ctatgaatgc ggtggctgtc aattacaaca cttagcttat caagctcaat
    46081 tggattttaa aaaggatctg cttttgcaag cattggaaaa attcaaacca gcaggctttc
    46141 gatcttatca acttttgccg acgatcggga tggatgagcc ttggcattat agaaacaaag
    46201 cacaatttca gttacgaaaa aataagcaga ctcaaaaaat tgaagctggt ttatacgaag
    46261 caaactctca tcagttagtc cctataacag actgcttggt tcaagaacct cgaacacaaa
    46321 aagtaatgaa tactgttgtt caactattga ataaatttga tgcacccatc tatgatgaac
    46381 ggacaaacag tggaatcttc cgcacaatca tggttagaat cggtgttaaa actggggagt
    46441 tacaagttgt ttttattact cgcagtaaaa aattcccgca aaaaaacgca atgatccgtg
    46501 agatcaatga acgactgccc gaagttgttt caatcatgca aaatgtccag gcacaaaaaa
    46561 cgtctctcgt gatgggggat gaaacgatcc acttatgggg aaaagaagcc attgaagaac
    46621 aaatcaatga agtgactttc gatctttctc ctcgtgcctt ctttcaactc aatcctcagc
    46681 agaccgaatt gctttatggc gaaggaatca aagcattaga tgtccagcct aatgaaacga
    46741 tcgtggatgc ttattgcgga gttgggacga tcggcttaag tgtagcaaaa caagccaaag
    46801 aagtacgggg aatggatacc gttcctcaag caatcgctga tgcaaaaaaa aatgcggaaa
    46861 gattaggata tcacaacact cgatatgaag tcgggacagc agagcaagtt ctgcctaaat
    46921 ggttgaatga aggttttcag cctgatggta tcatcgtaga tccaccacgt acgggtttgg
    46981 ataacgcatt gatccaatca ttattgaaat accctccaaa aaaacttgtt tatatctcct
    47041 gtaatgtttc tacacttgcc agagatctgg ttaatttaag taaaaagttc aagattgaat
    47101 atttacagtc cgtcgacatg tttcctcaga ctgcacgttg tgaagttgtc gtgaagatga
    47161 cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc tgccctgtat caagtaataa
    47221 gaacagccaa acaaaaatag ctcttcatgt tttatgaata ctgtacttgt gaccgaagag
    47281 ttaacaggag gacactattt atttaaaaaa agggttgtga catagttttt gtcacagccc
    47341 tttttgatta ttattggata ttcacgtcta tcacttgata aaatgcattt gtcgtatcgc
    47401 tgatattcca tactgctaaa atcacattat atccttttcg atcctgcgga agtgtgatcg
    47461 tttggttgac tgtttttggt ggaacagttg ctttgtcgtc tatttttgtg atcaattcaa
    47521 aatcactaaa tttcaaaggt tgattaggat tccaagttgg tttggtaatg tagtaatccc
    47581 aagtacttgt ccgatgttgt gctgttaaat tccaagtaat atttaatgtt cctggattaa
    47641 ccatgttttt atgccatctg ttagatgtct gttcatctaa aggctcaaag ccgctgactc
    47701 ctgcactagc aatttttcca tcaatgaatg tatttttggt agcttcgata ctttgcggtt
    47761 cccattgtgc tcttccgaca ttttgattta agtttcctgc tgctgatgtt cctaggtatg
    47821 cacggcttcc tggagaagta atataaccat gcgcaaaacc tggaatgcta aaaccgaaca
    47881 accctaaact aactaaccca ataaacaata acgtactaat ctttttcatg tagaaacctc
    47941 cttcatttga taaccacatt gtaaacgctt tattgtatta acacaaacat tatgctttta
    48001 taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat gcagattata acagaagtag
    48061 acgagaaaag tacaaataga aaacatgaga atcaaatcat atgatctttt tcaaaaacat
    48121 cattcatata aacaaatgtt caacttttta ataacaacaa ttatcaattt ttttcttact
    48181 tcacaaacta aatacaggtc ttgctgtgag ccttcatggt aaactaatat tatagaaagg
    48241 agttagtaaa atgaagatga taaaagatat tcgtttttgg gtttgtgtta taggaattgt
    48301 catattaggc tttttatcag ggttgcttag cggaaatccc ggaaaatatt actattcttt
    48361 gcaacttcca ccatttgcac cacctagctg gatatttggg ccgatgtgga ccttactgta
    48421 tatattgatg ggtatttctc tttatttgtt acttaatcac aacaacaaaa aacagcgaaa
    48481 caatcttgtc ggtctttttg tgattcagtt catttttaat tttatatggt ctgctctatt
    48541 ttttaattta agaaatattt tcattgcagc aatcgatatt acacttttag ttattttctt
    48601 gtcagtgctt atgtatcagt tgtggctgca tcatcgcctg gcaatgtggc tcatgattcc
    48661 ttattattta tgggtactat tcgcaactct attgaattat tcaatttatt ttttaaacta
    48721 agcgctaaaa agagacgtcc tgtaatttaa cacatagaaa aagtgccacc taagttagat
    48781 tttttgtcta atttaggtgg cactctttat taaccaaact atttttttct agtacccact
    48841 tgttgttcca tactcattat tctggtcata accataacca ttttgttcct gtccagcgta
    48901 aggatcataa ctttgagtat cttgacttgg tgtatagtac tgacttgtat cttctgtttg
    48961 ctgataatag gtattcggat cttggtactg atcatatgtg ttttctgaat aggaagaata
    49021 atcggtgtac ccttcactat tcgatccatc accgtttgtc gaatcgccat cttccgaatc
    49081 atcaaagaac atcattgaag cattctcatt tttcaaatta ggtaatgtat cgcttgtttt
    49141 tatatttaat tgtttcttca gttcattttg gatcgaaaga agatcatttt ttcctaaaat
    49201 ttgatagtag atatcattga tcatttgtcc ttcgccttgc aactggtctt gtttgattgt
    49261 ttcaaacgcc ggggtgtagt tcgtcgctac atcaagcatg tcatcccaat ctaagtccgt
    49321 cgtcacattg ttctcaactg cttttaaaat ttttctataa ttgcttacgc catctaaact
    49381 taaaacttta ttgacgattt tcgtcactac ttcccgctga cgacgttgtc gaccgatatc
    49441 gccttctgga tcttcgtgtc gcattcgaga ataggctaaa cctttttctc cattcaatgt
    49501 ttgttcacct actggtacat ggacaccatc caaagtaaag tcaattttat tattcacttt
    49561 gatgccaccg accgcattga tcaaatcttc catgccatcc aaattgatcg ttacataatg
    49621 atcaatagga atatcgagca gttgctcaat tgaatccatg gccatttcga caccaccaaa
    49681 tgcgtaggca tgatttaatt tatctaccgt tccataacct acgatattcg tataaatatc
    49741 tcggtccaaa ctgatgatcg ttgatttttt ttgtttcgga ttaactgtta ctaccatcat
    49801 cgtatcagaa cgtccttgtt ccgttcttcc taatccaccg gtatctaaac ctaatagcaa
    49861 aaccgaaaaa ggttctttgt catcaatgct tactctctca gaacgtttgg aggatattcg
    49921 attagagttt ttagaaattt tgtttactgt ttggctcgct tctcccataa atctgattcc
    49981 gtatgctgat aatccggcaa tcagcaaaac gaatacccct aacaaggtta atagaacttt
    50041 ttgccatcgc ttcataatac acctctgttt cacattttct aaaatattgt ctcatataac
    50101 tgttcaatca gcaaattcac tttttaatca taagaaaact ttaaaaaaca tttttgtgta
    50161 acgattatta ttttttaaaa tttctcaaaa ttcttaacta tcataccata ccgtgaaaaa
    50221 gatcgaaaga ccgaatacac gcagttcgca atcgttttat ctttttttat gtattttttc
    50281 cagaaaaagc gaacaacaag gtattttcca aataatcgtg cagtaaaatg atcgcacata
    50341 cctttcccat ctttttaaca gtctttgcct accgttcaga ttatcattcg atttcacgac
    50401 aatttcttcc tatgactggt ccttttgtta aacccatctt ctattcgttt tatttccagc
    50461 tcactgcatg gctcttaaaa tgactcgaac tagtgattgc attaccatca tcttttaatg
    50521 gatagatatg ctcctcttca aagtaaaacg attttctttt aaagtaatag aattgacatg
    50581 gtaatgagta tgtatactag tggtttcaca aatggtcttt tattcaacat ccaaaaactg
    50641 aaatttcttt aaaatccatt actaacgaag aaaatgttcc ttgcttgata attagttagg
    50701 acatgtcaag tgaacaaatg catttactta gccaaaaaat ctaaaaactt cataaataga
    50761 caaaaagaca cgactctcta agaagtcgtg tctttattca acaaattatt ataatttagt
    50821 cacttcagca gcttgaggtc cgcgtgcacc ttcaacaatc gtgaattcta cttcttgacc
    50881 ttcttctagg ctcttgaagc cgtctccttg aattgctgag aaatgaacaa atacgtcatc
    50941 tccgccgtct actgtaataa acccaaatcc tttttcattg ttgaaccatt taaccgttcc
    51001 gtgttccata aatgtatatc ctccaaaaaa gttcttgcaa gtaaccttgc aagaacatta
    51061 tacccaattt agaaaacgct agcaagcttt cgctctttta ttttccaaat tatttttaag
    51121 actgatatga cggaggaaat ggttattttg ctgcttcgaa acgtttgttt acttcatccc
    51181 aattaataac attccagaat gctgcaatat aatctggtcg gacattttta tatttcaaat
    51241 aataagcatg ttcccaaacg tccaaaccta gaattggtgt ctttccttcc atcaatggag
    51301 aatcttgatt tgcagtagag gtaatagcta attttccatt ttccattaca agccaagccc
    51361 atccagaacc aaatcgtcca gcggctgctt ttttgaattc ttctttaaaa gaagaaaaat
    51421 caccaaaagc ttcattaatc gcttctttta tttctcctgt aggttcgcca ccagcatttg
    51481 gtgccatgat ttcccagaaa aatgaatggt tagcatgtcc gccaccattg ttacgtacag
    51541 ctgtcttgat atctgttgga atagcgtcca tatcagataa taattcttct attgtttttt
    51601 cgcctaattc tgggtatttc tcaattgctg aatttaaatt cgtcacataa gtattgtgat
    51661 gcttatcatg atgcagatgc atcgtttctt cgtcaatata aggttccaat gcgtcatatg
    51721 cataaggtag atctggtaat gtgtaagtca taaaaaaatt cctcctcaat gttttcttaa
    51781 taatgtctac attacaaaga gtaacaaaga gaaggaaatt cttcaattgt tatgcctagt
    51841 cgtctttttc actttgacct acttcttctt caaaaacctc agtttcttta aaaataaaca
    51901 acttgctgaa aatatagttc gcaaggataa caataatttg agtgatgatt ttcgccacat
    51961 actcattgct gttcataaca ttgatcaaca ataccattgc ccccatgtcc aatccgtaag
    52021 aaaggatacg gtagaagaag aacttaccgc attcaataag tgcatgtgta aaattcggtg
    52081 attttgaatg gaatacccaa agtttgttcg ttacaaaagc aaacaataca gaacaaaacc
    52141 acgaaataga attggataag gccatactta aatcaaaata ttggcgtgcg agagcaaaac
    52201 taacaaaatt tacaatcgta gccaaaccac caaaaaagag atagactagt atctcccaat
    52261 atccttttgc ttctaaatat ccttttaact gtcgatactg cttcatgagc caacctacct
    52321 tattaaaaat tcttatttat catactctat atttcaataa ctttcatctt tatttaaaaa
    52381 aattaatttt ttttgatcct ttgcctttgt ctctgcttgg atcgtcacat gtgtaatacc
    52441 atattttaat tttaataaag aaattatacg aggatatatc ttttcaatct cgcttagtag
    52501 ctgatcttca aaatcaatat gtccgtcgaa aataattatc ttttcgctat actgccaaat
    52561 atggacatga tgaacatcct ttaccccatc gattgcttca atttcttgtt ccattttttc
    52621 atagtcgata gcaggtgcac tttgtatcaa aatagcggca gcttttttga tcaccattat
    52681 cgcttctatc aatatatata tcgaaatgat cagtgtaata actggatcga tccagtagat
    52741 atcgaaaaaa cggatcaaaa ttgctccgat aatcacactt accgaagaca gtgtatcact
    52801 taacaaatgc aaataactag attttatatt caaactttca tctgcttctt gtcgtaataa
    52861 taatactgag aacaaattcg cgagcaatcc aataactgct actgttagca tcaaatgact
    52921 atttatcttt tctggtgaag tgaaccgctt gaatgcttca acggttaaaa acaaggataa
    52981 tatgatcaat atgaatgagt tgatgaaagc actcaatatt tctaaacgct ggtagccata
    53041 cgtacgtttt ttatttgctt cttttcgggc cattttttgt gccccgtaag aaaaaataat
    53101 tgccaatgta tcactaaggt tatggaaagc atctgaaaca agagacaaac tccctgacat
    53161 aatccctcca ataaattctg ataaagtgat caccgcattc aaaaccacta ctccaaatag
    53221 tttttttgat gatctctgtg gctgtgtagg cactattcct tcctccattt tatttatatt
    53281 ggatagtctt tagacaagaa taacattttt ttgatatttc accaatcatt cagctgtttc
    53341 cttaaagcac ttgtatttca cttgatactt cgctagaatt gcaagtgatg acactactag
    53401 atgaggagta cttatgacaa caaaacaatt aattatcagt tcctttatac gattcaaaga
    53461 cctaaaggag gcgagaaatg tcccattttg gaaagccatt gtctatcttt tagttttgag
    53521 tataattatg gctttgccaa tctcttttca agtttttcaa gtcttaaaca acattcaatt
    53581 ggatgggcaa aagattgcta ctcgcattcc tgattttaca atccaaaacg ggcagcttca
    53641 aaccgaagaa aaagaaggat tcatttacca aacaaactcc attatcttca catttgatcc
    53701 agagggaaaa cgaacagaac aggacatctc tactgatttg atggggaatt ttgttagtgt
    53761 cgggatgtta aaaaacaaac ttatcatagc tcttcctaat acaggcacga cttctgcttt
    53821 gttgaacaat aaccaattag aacttcccta caccaatgaa tctttaaaaa acttaacagg
    53881 taagcagctc cgttcttttt taagtgaagc atctatacca ctttggataa aagtcctgac
    53941 atttatattt tctatttatc ctagttttct gaatctgctg atcactttgc tatttaccaa
    54001 cattgctgct tttctctatg cacgctttcg actaacaaaa gctacttttc ttgattgttt
    54061 aaaaacattg atctattcaa tttcattgcc tactataatt gcaacaatct tgatggtctt
    54121 tcttccttct tttgacacta gcgccttcat tgcttttgca ggaatcttta tttttgctca
    54181 agctgtcaaa ggatgggcaa aaatatcgat caattaagaa ataaagacaa ctcgttattt
    54241 ctacttcaat agaccctttt agaggttgtg acattttttt gtcacagccc cttttttatt
    54301 tgaaaaatat ttctttctca aaaaacaagc aaggcgcttc aaagttcttc ttgtatgcgc
    54361 tacacttaga gtaaagaaag gcgggaaatt aactatgtca gaaagaatca tttatgcaga
    54421 tcgtccattt cgtgatgaat ttatcgaaga aatccatact atagcgcctg gttatatctt
    54481 taaaacagaa ttacaaccag aggatctaca aaatgtagag atcagtttgg gctggaactc
    54541 agactaccaa gaaaaactat tagcctcttc taccttgaaa tgggtccaat ctatctcagc
    54601 tggtgttgat cagctacccc ttgagacttt ttcaaagaaa catattttac tttcaaatgg
    54661 tagtggcatc cacagtgaat cgattacgga gcatgtctta ggaatcatcc ttgggtattc
    54721 tcgtggtctt tttcaagcac aaaaggcaca gagtgacatg aaatggttag gttcatcggt
    54781 ccattaccaa tctatccaag ggaaaaaaat actaatcatt ggaactggcc atattggaaa
    54841 aatgattgca aaaaaatgca aagcattaga catgaactgc tatggaatca atacatccgg
    54901 tcatccagca gaaggaatgg aaaagacttt ttctttaaat caactaaagg aagttcttcc
    54961 tgaagtagat ttcgtagtca atatcttacc tctaacggag gaaacaactg ggctctttga
    55021 tcagcatatg tttgaacact ttgatccaaa atctgtattc atcaatgttg gccgtggtgc
    55081 ttctgttaag acacaagatc tggtgcaggc tttaaataac cagcaacttt cctttgcagc
    55141 attagacgtt tttgaggaag agcctcttcc acaagatcat cctctttgga aaatggacaa
    55201 tgtactgatt acttcccaca ttgcaggttt gacacctgat tttcaaaaga aattaatggc
    55261 tattttttta accaatctga aaagctactt tgccacccat gagcttcaaa ccaatcaagt
    55321 aaaattgtct gcaggatatt aatagctgaa aacaatattt tcaaaagaaa aaagagaagg
    55381 tgacaaaaat tgtgtcaccc tctctttttt tattgttttt taaagtgata ggttggctcc
    55441 tccaggttgg gattataatc aacaagtaaa tcatatcctt taaagaacca ttcatctgct
    55501 tcctcgataa aaaaaagtgt cccatcaatt tccactttct ttacaggatg ttctggctgt
    55561 tcaactgaca ttccaatcga aaaaccatca tgaacctctg ttttgccgta gacttttcca
    55621 aaaaaacgta ttccgtaagt ttctggcaga tcaatttctg agtcaaacca cttttgtgct
    55681 tttggcgtta ccgttaattt catcccaaca acctactttc tcttttcttt ctattgattc
    55741 atcttatcgt ctagaatatc cacatcgcct gtctctccaa taaccagtag attatcattt
    55801 tcacgaacat attcatctgc tgcaggagaa gcgataaccg tttgatctac tcttcgtatg
    55861 gcgactactg ttaagtcaaa acgttgcctg aaatttaatt cagctaatgt tttgttgaaa
    55921 aatttaggat tggagactcg gatttctgct aaagaatatt tatctgacaa ctctaggtaa
    55981 tctaaaatat tctttgacac taaattatgc gcaatcctta ttcccatgtc tcgctcggga
    56041 tggacgacgc gatcagctcc gatcttttca agtactctgg catgatactc attttgggct
    56101 tttgctaaaa tatttggtac gcccatttcc tttaccatca gagtaactaa gatactggct
    56161 tgaatatctt ctccaatagc gacaattaca tgatcgaaat ttcttatgcc taatgatcga
    56221 agtgtcattt catcctgtgc atttgccaca acagcatgag tggctatatt catatattca
    56281 ttgacccgat cttcattact atcaatagcc agtacttctt gaccagcttc gatcagtgtt
    56341 cggcagatac ttccgccaaa tcgtccaaga cctacaattg caaaattttg tttcaccgtt
    56401 ttcctccttt agtatcttct tttctcagta taacaaagcc tttacaaaaa caaaagcaag
    56461 catcattatt gtaaaaaagc caagaaaaat aatagttatt ttctcagctt ttgattatcc
    56521 tctttatcat cgtttttatt tcaccaaacc atgtttgaat gcatagatag cggcttgtgt
    56581 acggtcttcc acttctagct tagccaatat attggaaaca tgtgttttta ctgttttcag
    56641 tgtaataaac aattcgtccg ctatttcctg attacttttt ccttcagaaa tcagcattaa
    56701 aatttcattt tcccgattcg ttagttcttc atgtaataca ggctcatttc gccgactcat
    56761 tttttccatc atttttgttg tcacttctgg ttctaatact cgctcgccac gttgcgttgc
    56821 ccttatagca tcagcaattt catgtgcggt agaggtcttc aacaaatacc ctgctgcacc
    56881 tgcttcaatg gcaggataaa ctttttcgtc atcaataaaa ctggttacga taatgatttt
    56941 agcttctggc caatctttta agattgcttt tgttgattcg ataccatcca tttcttccat
    57001 gactaagtcc attaaaatga cgtccggtcg aagtgtcatc gccttctcat agccttgtcg
    57061 tccattttca gcttctccaa ttacttcaat gtcttcttga atagataaat aaaaagagac
    57121 gcctaagcgc accatttcat ggtcatctac taataaaact tttatcatcc ttatctatgc
    57181 ctccttcatc aaagggacct tgatttctac acttgtacct tgacctttaa aactaatgat
    57241 ttttactgtt ccaccaatac cagctactcg ttctttgata ttgttcaatc cataacttcc
    57301 cgttttcgtt tcattcatat taaaccctgt tccgtcgtca ataatacgta acaaaagatt
    57361 attgtctatt ttgtgcaaat atacctctaa ttcattggct ttagcatgtc ttaatgtatt
    57421 tgataacaat tcttgaacga ttcggaacaa gtgatcctca atggaactag atagttttac
    57481 atcttctaca tcccatttca gcgaaatctg gattttattt tgcaattcct tcaataactg
    57541 ctcgatacct tgctttaaac ttttctcttc taaattgact ggacgtagat gaagaagcag
    57601 cgcacgcatc tcagactggg aagcgttgat gatctctgct accattttca actgcttgcg
    57661 aaacatttct ggtgtctcgc ttttttctgc ttgctccgtc aatgccgaca tcatcatcat
    57721 tgctgcaaac aattgttgcg aaactgaatc atgcagctca cgggctaatc gatgtctttc
    57781 taattctaaa atttcttctt tggtttgtcc atctacatat tggggacggc tcgttacaat
    57841 ttgtaattca ctagatactt caatcatttt ttcttttatc ttagtgattt ccttatcaat
    57901 atctttgatg tataaatcgt ccgatgcact tgggatcgga agaagcaaca atttggattc
    57961 ataattgcca gaagaaagtg cacgcagctt ttcttcgatt ttcccgtatt ttgtcttttg
    58021 aataagtgat aataatagaa agacaattaa tcctacacct aaggaaatgg ctaacaaatg
    58081 gaagataagc ggaacatata ataaacgtgc acgcagtaat tctccccacc aatgactttg
    58141 attgctggca taaaaataag tgaaaagtga aaatagaata ataaggaaag ccgcaatccc
    58201 cgaataaaca gctagcatcg ctctggatat ttttcccatc atattcgtat cacctcgaca
    58261 tctccaatca aggtattagt aataatcttc aatctacgag ggttttcatc ataatcactg
    58321 ctgtagattt tgatttgttc atttttcaaa gaaaattgct cttcttcaaa caagacattt
    58381 cctactaatg tcgcatgctc taatcggatg gctacgccca aaggtactaa gatccgtgtt
    58441 ctgcctatcc cttttcttac aatcacaata ttatcatctt ttggcaaaag cgtattgccc
    58501 aaatctatga tagtatcacc agaaatgacg gcgatgttga tatcgtccca ttcatagacg
    58561 tcgtttccaa tacgttggtt accgaataat tgctgtcttt tccgctcatt attatgtgtt
    58621 tttaattgct ctgtttggat catcatgatc tgtttctttc gccaaaaagc atttttggtt
    58681 aaatctatcc ctgaaatctc tacacctttc agaccaataa ataaaacggc aaatacagcc
    58741 atcatccata aagcaggact gttgactaag ctaaaaaaaa tgaccaaact tcctaatatc
    58801 aattgaaaat tttgaaattt agtacgagga tgtttgcgca tagctagata tatattgaaa
    58861 ataccgaata tcactaaaag caaaagtcca gtattgttta cgatttgcca aacagcaaat
    58921 aacagcagta gtgcttcaac taccacaaaa aaacgccaag aactattcat cgctctttct
    58981 ccctcctgac acattctcat ttcatcatac ctattttttt aactgttggc tataggactt
    59041 tagatgtaag atcgtttgtt gaaatctaaa atacacaaag agaaaaagat ctagagtgta
    59101 tcatcagtaa gatgaactct ctagatcttt cagtcagact acgcttgttc tactttgacg
    59161 attttaacta acatatcgcc acctggagta gcaatagtta cttcatcatt tttacgtttg
    59221 ccaatcaatg cttgcgcaat aggagaatca ttggaaattt tgccagaaaa cggatctgct
    59281 tcagcgcttc cgacaatcgt gtactcttct tcttctccat ctggtagttc gatgaatgta
    59341 actgttttac caattgatac ctcatctgca tctacaccgt cgttatcgat gatttgagca
    59401 aaacgaatca tattttcaat tgttgtgatt cttccttcaa caaatgcttg ttcatctttc
    59461 gctgattcat attcagagtt ttcggaaaga tctccgaaac cgcgggcaat tttgattcgt
    59521 tcaatgattt ctccgcgttt gactgttttt agttcttcta attctttttc taatttttct
    59581 ttaccttcta gagtcattgg ataaactttc tctaccatgt gtaacgtctc cttttttcga
    59641 taaaataccg caaaaggtaa tcttttgagg aatatagtcc aaaaaagatt accacgcttt
    59701 tcttcaaatg taaatgtttt tctaaaaatg atcaatgtct agagcctgtt tttctaagaa
    59761 ttatttacat atttttccac taattccata tgttcttcat aagttttagc gaaataaaca
    59821 tttccagtgc tcgtatctgc tacgaaataa taatagtcat tttctgctgg ttctaatact
    59881 gccttgattg cctcttcgct tggattgtca aaaggtccag gtccatagcc ggtattggta
    59941 tacaaattat atggtgaatc tacagctgta tcttcatacg tcactaattc tttgtgttca
    60001 cctaatgcgt ataaaacaga gatatctgac tgaagtggca tatttgcttt gattcggtta
    60061 aagaagactt gtgcaatgtt tttacgatca ttttctttta cgccttcttt ttcaactaga
    60121 gaagctagag ttaaaacttc ttgtacagtc aaatttttct gcttgatagc tgaataatag
    60181 ttttgcatga ccgtattcgt cttgttcacc atttcaatca ctagatcctt aagcgaagta
    60241 ctcgtgtaat aatcatatgt ggctgggaat aagtaacctt ccaaacggta ttttgtgttc
    60301 tcagctttag atgcactttc caacagttct gggaattttt ggtgcaactc gttaaagaaa
    60361 gtctcatcat tcactaaatc taaaaattct ttcttgtctt taccagttac cttcgctacc
    60421 cgttcagcaa tctgatcgat atcgtaccct tctggaatgg caattttccc atctgcaact
    60481 tttgttggct cagaagtacc gccttcttgc aactgtttgc caatctcgtc aagagtcata
    60541 ttaggcgcta actgataata gccagcttga aagccagtta aatttttaaa ttttgtataa
    60601 taattgaaaa caatcccgct tttaataata ttgtccttct ccaaaatctc accaatctgc
    60661 ttgttagaag agccactcgg gatctcgact tggactaatt ggtcatctga tttatctaaa
    60721 ggcttcaacc cgctatctac ataacgatac acggtaaatc caagaaatcc gccaataatc
    60781 aataatgtaa gagcaatcac taaaatgatc ttcctcacaa tcttatcttc ttttttacgc
    60841 agatttctcc gcttgtcgat tatatctgct gtagctgcct tactggcttc ttttttatct
    60901 ttacttgggt gttgtttgtt tcctgacaaa acaactcctc cttactatca agttcgtaac
    60961 tttattcatt atacatgata tttgaattgg cgtgaatgat tttatttaaa tattctatca
    61021 aaaatgtaag tagtaaatcc attactataa gattaaaata aatgttatca agatacaagc
    61081 tattttagct ttattctttc tgtaaaaaag aaaggagact aaataaacta ttatgaaaaa
    61141 aggaaaacat gctaaaaaaa gaaaatattc atttttaatg atcgttgtcg tgttgtttag
    61201 ccttagtgcg ttctctacag gaactattct tggatggcaa ttttacaata atgaacactc
    61261 tcagatagtt gcccatgctc aatcagctca aaaaaagttg atactgacta ccaatgaaca
    61321 acagctcgtt gaaaaaatcg atcaactatt aagaaaaaat gattatattg gctcaattta
    61381 cgtaaagaaa aataatcgca tcatcatgga aaaaggctat ggctatgcga ataaactcac
    61441 gcaacaacca aatgatcctt ctctttatta tcagattggt tcggttcaaa aagcattgac
    61501 tactcttttg attttaaaac aagtcgagcg tgggcacctt tctttagata ctaagctggc
    61561 tcaattctat ccacaaattg ctggcagcca gcaaattact atccgtgact tgctgtatat
    61621 gcgctcaggc ttgcaccgaa ctgcttctcc aaccataccg atgactgatg aagaagtcgt
    61681 tcaatttgcg attcagcact taaaatttac agattatcag acctctcatt atgattcatt
    61741 gaactttacc atattgactg gaattttgat caaattaaca aatcaaccgt atgaaaaatt
    61801 attgaccgat gatatcatcg aacctttagg attacagcat acaaaatttt atgaccaagt
    61861 caaaaattca tccaatcatg cactatccta tcaaatgtct aaagaggatg attactttaa
    61921 accactgaca gaatctgaaa cagagatcca taacgaatta gggactggta atatcagtat
    61981 gtccgtctat gatttaaata cgctgtttac acaagtttta tctggaaaac tagtttccaa
    62041 agacttactc ttctcattat ggcgtgaaaa tgcgaatgga catccatata gtggtggggt
    62101 atatagcgga gataattata tcctgtcgca aggaaatatc gactcttttg atacatctgc
    62161 tatatttagc aaagattcac aggatgctat catcatggaa agcaatataa aagctgacaa
    62221 aactatcaaa ctgcctactg ctgatctaag aaaccaaatc tatgacctga tggaaggaac
    62281 tactaagttg gcaaatagct gatatgatga aaagatagca aatactactt ctttgaatag
    62341 catttgctta aaaaaagtac tcgactaaac gtaggaaaga gtgtgggaca aatctaaaaa
    62401 tcaatttttg ctacagactt taattccaaa taaacagaac agaaagaggt gttcttcttt
    62461 ctgttctgtc caaattattc taagatttct ctttaccaac attatttgac aaagggccta
    62521 ttaaatctaa aatagtatct ttagattgct aaaatatgtg ctagcaaatc attcatggct
    62581 tgttcttatt tttaatttta tgcaataaaa aagaagaaca attagcgtga ttatagaaat
    62641 aaataatgag attttagaaa aaaatgtgta tgaatacctg attgttactt tatttattcc
    62701 actttcactt tttactgtaa caaaaggacc tccttgtttt agtactgtag cattttttga
    62761 attaacagta accgttaatc ctttataccg gaatacaggt aaaactattg ttttgccttt
    62821 tgaagattta aacgtaaatg taatttcatc tttatttgga gaaaagctac tataaataac
    62881 ttgaccatct tctgtaactt gatggttttt caaaagcaat tgatcttttt tatagcctat
    62941 aggtacataa tcaaaattct caaattcttc aagtttattt tccatttgtt cattagaata
    63001 agttccttga aaattcattt ctttcaccat gttaactact gatgaataat ttaaaattga
    63061 aatagctaat attaataata gtataaaatt tcttctcctt gtataagaaa atttttccaa
    63121 ctgtggagaa ataaatagag atactgaaaa agatatgaac aatgttgaaa atatcataaa
    63181 acgccaagga gcttgaataa tatttaaagg agtattttgt aaggcaaacc atggaaatat
    63241 ttttgtacaa agtagaatag atattatacc cattatataa gtgattttag ataagattcc
    63301 taatttttta aagttaaatg ttagtataat taaacaaata agcaaagtta agccaatacc
    63361 aaatgatagt aattctgaat ctatacttcc aatcaaaaac tctttaccca gataaattgc
    63421 tcttttttgt aatatatcca cataaggtct attcagatct tgatacaatg tctgctcaat
    63481 cataggacct ataaacgcta gtgaaagaag taaagtaact atagcagctt ttattaattt
    63541 aataattaag aagatttcta ttttcttttt ccgataaaat tgaataatta aagcaattat
    63601 aatcattacc atagtcatag ctacagaaag aacatgagtg taaattaata aagtcatgct
    63661 aatcgccaac ataacccaag attctttttt tgagtcgtaa agctttataa acccgagtaa
    63721 aataagagga agtattgaca ttgcgagtaa ttcccccatt gcccctcgaa gaaatatttc
    63781 tacactccta aaagaagatg ttgtatatat aatagcgaaa aaggagctag taacatgttt
    63841 tttggtaatt tcatacatta cataatgaca tataaataga gtaatgagcg taacaatata
    63901 aagaaaaagg ttatagccta ttgctaaatt agtaaacttg atcaataaaa ataaaggata
    63961 tagagttaac catgggtaaa aattatttac ttgcatgcca tatgatctaa acgtttcaaa
    64021 attaataggg gagctaaaaa tagattctaa acttaacgca cgattaatgt gaaatgccgt
    64081 atcataaaag ccaaatattt ccatgttttt aaatgctgga aataaatata ataaactaac
    64141 aaatgcataa actataaata tttttacaga aaaaattttt ttcaaattca tataccacct
    64201 catgtttttt tatattacat atagtatcat ttattttttt taaacactag attagtcact
    64261 atataaaatg tgattaattt tattattaat aaaatatttt ttatattaca aaagtagtgt
    64321 ttca
//
LOCUS       DBBGSP010000012        59066 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000012 DBBGSP010000000
VERSION     DBBGSP010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 59066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.012"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..237
                     /locus_tag="ACIZE9_000885"
     CDS             <1..237
                     /locus_tag="ACIZE9_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGC6092768.1"
                     /translation="DATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKH
                     LPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(590..1438)
                     /locus_tag="ACIZE9_000886"
                     /pseudo
     CDS             complement(590..1438)
                     /locus_tag="ACIZE9_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1591..2703
                     /locus_tag="ACIZE9_000887"
     CDS             1591..2703
                     /locus_tag="ACIZE9_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HGC6092769.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(2781..3074)
                     /locus_tag="ACIZE9_000888"
     CDS             complement(2781..3074)
                     /locus_tag="ACIZE9_000888"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HGC6092770.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3242..3556
                     /locus_tag="ACIZE9_000889"
     CDS             3242..3556
                     /locus_tag="ACIZE9_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HGC6092771.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3577..5556
                     /locus_tag="ACIZE9_000890"
     CDS             3577..5556
                     /locus_tag="ACIZE9_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC6092772.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5569..5895
                     /locus_tag="ACIZE9_000891"
     CDS             5569..5895
                     /locus_tag="ACIZE9_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HGC6092773.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            5911..6429
                     /locus_tag="ACIZE9_000892"
     CDS             5911..6429
                     /locus_tag="ACIZE9_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092774.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6429..7781
                     /gene="celB"
                     /locus_tag="ACIZE9_000893"
     CDS             6429..7781
                     /gene="celB"
                     /locus_tag="ACIZE9_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGC6092775.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(7865..9370)
                     /locus_tag="ACIZE9_000894"
     CDS             complement(7865..9370)
                     /locus_tag="ACIZE9_000894"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGC6092776.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9462..10052)
                     /locus_tag="ACIZE9_000895"
     CDS             complement(9462..10052)
                     /locus_tag="ACIZE9_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC6092777.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10231..11877
                     /locus_tag="ACIZE9_000896"
     CDS             10231..11877
                     /locus_tag="ACIZE9_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGC6092778.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            11926..12645
                     /locus_tag="ACIZE9_000897"
     CDS             11926..12645
                     /locus_tag="ACIZE9_000897"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGC6092779.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13124..14071
                     /locus_tag="ACIZE9_000898"
     CDS             13124..14071
                     /locus_tag="ACIZE9_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092780.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14083..15003
                     /locus_tag="ACIZE9_000899"
     CDS             14083..15003
                     /locus_tag="ACIZE9_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6092781.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15044..16501
                     /locus_tag="ACIZE9_000900"
     CDS             15044..16501
                     /locus_tag="ACIZE9_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6092782.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            16846..17460
                     /locus_tag="ACIZE9_000901"
     CDS             16846..17460
                     /locus_tag="ACIZE9_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGC6092783.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17453..19177
                     /locus_tag="ACIZE9_000902"
     CDS             17453..19177
                     /locus_tag="ACIZE9_000902"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC6092784.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19174..20625
                     /locus_tag="ACIZE9_000903"
     CDS             19174..20625
                     /locus_tag="ACIZE9_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC6092785.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21098..23251)
                     /locus_tag="ACIZE9_000904"
     CDS             complement(21098..23251)
                     /locus_tag="ACIZE9_000904"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGC6092786.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23253..24299)
                     /locus_tag="ACIZE9_000905"
     CDS             complement(23253..24299)
                     /locus_tag="ACIZE9_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6092787.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24449..25738
                     /locus_tag="ACIZE9_000906"
     CDS             24449..25738
                     /locus_tag="ACIZE9_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGC6092788.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            25751..28453
                     /locus_tag="ACIZE9_000907"
     CDS             25751..28453
                     /locus_tag="ACIZE9_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGC6092789.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            28438..29295
                     /locus_tag="ACIZE9_000908"
     CDS             28438..29295
                     /locus_tag="ACIZE9_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGC6092790.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29366..30223)
                     /locus_tag="ACIZE9_000909"
     CDS             complement(29366..30223)
                     /locus_tag="ACIZE9_000909"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGC6092791.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            30434..32605
                     /locus_tag="ACIZE9_000910"
     CDS             30434..32605
                     /locus_tag="ACIZE9_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HGC6092792.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            32673..33014
                     /locus_tag="ACIZE9_000911"
     CDS             32673..33014
                     /locus_tag="ACIZE9_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HGC6092793.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33290..35044)
                     /locus_tag="ACIZE9_000912"
     CDS             complement(33290..35044)
                     /locus_tag="ACIZE9_000912"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092794.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35055..35891)
                     /locus_tag="ACIZE9_000913"
     CDS             complement(35055..35891)
                     /locus_tag="ACIZE9_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HGC6092795.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(35893..36576)
                     /locus_tag="ACIZE9_000914"
     CDS             complement(35893..36576)
                     /locus_tag="ACIZE9_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HGC6092796.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            complement(36735..38129)
                     /gene="uxaC"
                     /locus_tag="ACIZE9_000915"
     CDS             complement(36735..38129)
                     /gene="uxaC"
                     /locus_tag="ACIZE9_000915"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HGC6092797.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            complement(38168..39667)
                     /locus_tag="ACIZE9_000916"
     CDS             complement(38168..39667)
                     /locus_tag="ACIZE9_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HGC6092798.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            complement(39660..41081)
                     /locus_tag="ACIZE9_000917"
     CDS             complement(39660..41081)
                     /locus_tag="ACIZE9_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HGC6092799.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            complement(41141..42133)
                     /locus_tag="ACIZE9_000918"
     CDS             complement(41141..42133)
                     /locus_tag="ACIZE9_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6092800.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            42365..44563
                     /locus_tag="ACIZE9_000919"
     CDS             42365..44563
                     /locus_tag="ACIZE9_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092801.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            complement(45021..45893)
                     /locus_tag="ACIZE9_000920"
     CDS             complement(45021..45893)
                     /locus_tag="ACIZE9_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6092802.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            46193..47167
                     /locus_tag="ACIZE9_000921"
     CDS             46193..47167
                     /locus_tag="ACIZE9_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092803.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            47189..47881
                     /locus_tag="ACIZE9_000922"
     CDS             47189..47881
                     /locus_tag="ACIZE9_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGC6092804.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            47847..49355
                     /locus_tag="ACIZE9_000923"
     CDS             47847..49355
                     /locus_tag="ACIZE9_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC6092805.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            49429..50532
                     /locus_tag="ACIZE9_000924"
     CDS             49429..50532
                     /locus_tag="ACIZE9_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGC6092806.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            50535..51872
                     /locus_tag="ACIZE9_000925"
     CDS             50535..51872
                     /locus_tag="ACIZE9_000925"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HGC6092807.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            51859..52737
                     /locus_tag="ACIZE9_000926"
     CDS             51859..52737
                     /locus_tag="ACIZE9_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HGC6092808.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            52734..53657
                     /locus_tag="ACIZE9_000927"
     CDS             52734..53657
                     /locus_tag="ACIZE9_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HGC6092809.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            53654..54064
                     /locus_tag="ACIZE9_000928"
     CDS             53654..54064
                     /locus_tag="ACIZE9_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HGC6092810.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            54068..55636
                     /locus_tag="ACIZE9_000929"
     CDS             54068..55636
                     /locus_tag="ACIZE9_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HGC6092811.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            55876..57294
                     /locus_tag="ACIZE9_000930"
     CDS             55876..57294
                     /locus_tag="ACIZE9_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6092812.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            57306..58616
                     /locus_tag="ACIZE9_000931"
     CDS             57306..58616
                     /locus_tag="ACIZE9_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HGC6092813.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
BASE COUNT        19016 a        10316 c        12020 g        17714 t
ORIGIN      
        1 gatgcgacac cagtaacttt caagatcgaa aaagaacaag aagtggcgat ctttttaaca
       61 aaagagaata gaaaagttgc tgatagctca gatataagag gaaacaatcc aacaagcagt
      121 ggaaataagc atcttccaaa aactggagaa accatcatta gccagtttat attgtcaata
      181 ttgggtgtgc tacttgtttt catcagtata aaatttagaa agaaacgaaa tatatgagct
      241 aaaataaaaa attgaataag catagttttt aaaatcaact agtacccatc aattgaatgg
      301 aaactaccga ttttagaagg ggtatacaaa caaatattag tatcggagta gagaaggttg
      361 aacccaacca gtaaataagt aaagacaatt ttgtgctgcg ttgagaagtg aaaaataaac
      421 ctttgtagta atactagtta ataaaaaata tacaaaaaca ctgcgaaaat cattcttgag
      481 tttcgcagtg ttttttgcct aatgactcaa gtttattggg taatactttg attttctttc
      541 tacaaataat cagcgatcag ttgtaatttt ttctctagtt ttaatggctc tttgtcaata
      601 aggagaaaaa caagtcgggt cttttgtctc ggaaagcttc aaccaactcg tgaataaagg
      661 ttacgcctcc ttgaaaggcg tggaaaaacc aagtaatcga tcaatcacca atttcgcatt
      721 tggtagaaca tgtttggtga gctgaaagta ggtggcgttc atgtctgtaa ctaagaattc
      781 tatttcttta ggattagtgc agctaaggaa atagtttgtt aatcgaggaa ttttttgtgt
      841 aggtaaattt tctcgattaa tttttctgtc tcgccatccg cggaaataaa actcagttta
      901 tcctcaacgg aaacgtgaga acgaaattca caaccctcaa cactcaagac agaattcttt
      961 tggaagactt tggtaaatag cttctcaact ctttcaatgt gcgaataacg gttgtcaaag
     1021 atacctaaca acttttcgaa ataaaaaata acgacacttt ttcagtcagt aaagaagtga
     1081 ttttatgtct gacatgattt gaaatcgagt gccttggacg gataaaataa ctttgagcgt
     1141 tccaatggct tcgacagttt ttacaggtat agcgctgctt ttttaggcgt ataaccattg
     1201 gcatatgatt atattattca aagtggacaa tggtttcctt cttcttgttt ttcaccacca
     1261 ttaatttcct atttccatct accacagcag aaccacaatt tctacagaca catggagcag
     1321 ggaagagaac tgcagcaacg atcaatgttt ttttcttctg taaggtttcg taagagacct
     1381 ctgtaatcat caaatttttg tctattgatc tcagaatttt tttgatagaa ccattcataa
     1441 agcatatcgt tctctcagtt gtttattttg tggtgattta atcatacaag aaaacgatat
     1501 gtttttttat aaaaacatga ataggaaaaa tagttgacaa gaaaatgaca acgccatatg
     1561 atgttccata gtatttacaa cctgtcatag atgactgtaa aaaataaaag taaaaagaaa
     1621 ggacgacaac aggtggattt ttatcagtct ctacaactag atccgtttat tttaaaacaa
     1681 aaaatacgag aagcagcttc taaaaaagaa aagtgcatgt atatttgttc attgttttta
     1741 cgatcattat tcatcgtatt gtttgccatt tgttttatca ttataattac aacattattt
     1801 gaatcgaagc ataaaccata cgctgtggtt ttattctgta tgttgatgag tattcgtttt
     1861 gttgactttg gttataagat ttcccattcg atcataggtt tagcaatcgt catgttctca
     1921 ctattagtag caccgtatgt ccagctgatc aaatggtcag ttatgggcat gttgattcat
     1981 tttattttac taagcagcat attaatggca accgctagtg atcccaaaat ggggaatgct
     2041 tctttgtacg gcttttcata tctctttatt gtttattcgt tacctaaaga ttcgttgaac
     2101 aagaatttct ttacacaaac aagtagctta ttatttttgt ttttttgttg gttttcagtt
     2161 ctcctttaca gaaaacatcg agaaaagaac aaagacaaaa gcttgtttaa agagattttt
     2221 ttgaaaggca tgtattcgca ggaaaaaatt tggatgctca tctatgcatt tggcattagt
     2281 cttttgatcg ttgcaggaga gtatgtccct tttcagcgat tgatgtgggc agggtttgca
     2341 ttttcttcta ttgtatctag ctatggattg atgtcgattg gtttcaaaga acgagcagta
     2401 gaccgaatca ttggctcatt gattggatgt gttttattta ttggtatcag ccaatttatt
     2461 ccttttaact gggtcggtat attaggtggt ctagctttag gtgtttgttc tacctataga
     2521 tataaaacag tttttaattc ttttggtgct ttggcaatca ctgccagttt attcggggtt
     2581 ccaggagcag taacgatccg catttttgag aatatccttg gggtatgttt aggaatcatg
     2641 tatattgggg tgactgaaat acttatccga aaaataagag aaaaacacgg tttgaatcat
     2701 tagatgagat cgaataaaaa ataaggaaaa agtgaagata cacatggatg ataaattgct
     2761 atcattccat gtgtatcttt ttacggtaaa tcagtgaaac gttcgacttt catttttaat
     2821 ttatactttt tacggagttc gtttatttga gccatcattt cggatttgtg atgcttttcg
     2881 attgcttctt catctttcca acggtcgatc agtaaaagag attctggatc ttctagtgga
     2941 aagtaatagt catatttctc gtttccttct tctgcacgaa tcgctttgac aatgtttctt
     3001 tcgaccattt cttctgcaaa ttttctggct tgtccatttg tacttgtata caaaatattc
     3061 actgtgatac tcactaaatc ccctcctgaa aaaattctat cactagtata tcacggtgcc
     3121 agaaattatt attcaagata tgatacacat tttttccgca atgctacgga aatatatatt
     3181 ttgaatagaa aacgcttaca agatatgctt ggtttataaa aataaaagga gtgattgatt
     3241 tatgaaaaaa gcattgatta tttgtgcggc aggaatgtca tcctcgatga tggcctcaaa
     3301 gacaacggat ttctttaagc aaaaaagaga agaggtactc gtagatgcag tttcagctac
     3361 agaaggcgat aatatgatta agaatagtga ttttgattta tttctgatca gcccgcaaac
     3421 gacgatgttt ttggataaat tcaaaaaatt aggagaatct gttggaaagc ctgttgttag
     3481 tatccctttc caagcgtatg tcccaatccc tacaggcatc cagaagttag cagaggtgat
     3541 cgaagagaac atatgatgga ataggagtgg atgataatga aacagaagga aaaattgctg
     3601 ttgagatatt tgattgatca caagaaggag tatgtcacca gtcaacgttt agcttctgaa
     3661 ttgttattat ctgatcggac aatccgtaat tacttgcagc ggatcaaaga gttagtagaa
     3721 aaaaacggag gtaagatcat tgctaaacca ggttatggct accaactgca tattttacaa
     3781 agactgacat ttgacttgtt tttgagtcgg caagaaatag tacctggata tgctagagaa
     3841 ccgcaaggat tttatgagtc cgaagatcga caaaagtata tattgaacca attgcttttg
     3901 gaagatgcca ttctttttat ggatgatttg gcagaagagc tttatatcag tcgttccagt
     3961 ttgacaaagg acatgcaaga aatcaaggag cgattgattc catattcact aaaaatcgtt
     4021 tctaagcatg gtcaagggac atggatcgaa ggggaagaaa gaaatcgacg gcattttatc
     4081 atggatactt tttttggaaa ccattatgga aattcattga aagaatattt agggcaaagc
     4141 cgttttttcc cagacatcag ttttgaagag ctagtcatta tcattctcga tgaaacaaga
     4201 gaagctaagt taaaagtttc ggattttatc atacagaatc tgactttaca cttggctttg
     4261 gggatcaaac ggctccgaga agggtttgaa atcaaggaat taggcatcga acaagaagtt
     4321 tctaagcgag tagagtatca agtggcgcag cggatcgttc aacgtattga ggtaatcgca
     4381 ggtgtatcgt ttcccgaaga agaaattgct tatttgacat tacatctcat ggctaagtcg
     4441 aatcacaaag aaaatcaaaa tgatcaggaa ctatcaaagg aattagcgaa agttctgaaa
     4501 agattgtctc aggaatttca tttttcatta gtagaggatc tccagctttt caatggacta
     4561 ctcgatcatt tgtcaccgat gatgattcga ttgagccgag gtattcgcat tgagaaccca
     4621 ttgactgagg agataaagaa agaaaatccc aaagtctttg acgcagtaaa aaggcatttc
     4681 agcaacatgc cggctttgaa aaactatacc atcaatgaag atgaatgggc ctatttggct
     4741 ttgcatctca tggcggcatt ggaaaaagaa agagctgcgc ataaactaca tgcattgatt
     4801 atctgtgcaa cgggttacgg cagtgcccaa ctattaaaga atcgcgtagt cagtgaattc
     4861 ggtaaaaata ttacagtggt aagtgtaaaa ggctattatg agatcaatga aacaacttta
     4921 aaaggaatcg acctgattat ttcttctatt gatctttcga caatgttttt caaaattcca
     4981 gttttacatg tcagtatttt tttgaatgaa gatgatgttc gtaaaatacg aaaggtagtt
     5041 ggagaatcta taccctatca ttcctcagat agaccgatac cagcattttc tctacagcaa
     5101 aaaaagcaga tttacaccga acagttgtct gaaaaatttt tcaagactta tacgtacgaa
     5161 ccgaaaaagg aagaaattct tcatgatttg ctgcaaaagc tgagcataaa tgaagaagaa
     5221 ggatatataa gagaaatgcg aaagcagatc cagcaacgtg aaaatatggg acaaatcata
     5281 ttcagtgata cagtggcagt cccacatccc gctgttccag ttggaatcga aacaaaggta
     5341 gccgttgcat tgattccttc tgggatgcag tgggatcaat atcaagaaat tcattttgtt
     5401 tttttagttt cgccttctta tgtcgaaaat gaaggaatta cggtcgtgac taaagcaatc
     5461 gttaggttag ttgaccagct aaaagtacag caggaaatct tagctgaacc tatttttgag
     5521 aatttcagca gtaaatttat caaactgatc gaataaggag gaaaacagat ggctgaaaaa
     5581 ataaacagtg aaacactaca agtgacttct tttgatatca ttttccatag cggaaatgca
     5641 cggacactga tacatgaagc atttcgctcg atgcgtaaag agatgtttga agaagtagaa
     5701 gagaagttgc gacaagcaaa tgaagagatt cttcatgcgc atcagtcaca aactcaactt
     5761 ctgaaagaat atgccagcgg gacaaaaata gaaatggaaa ttatcatggt ccatgcacaa
     5821 gatcatctga tgacgacgat gacattattg gaagttgcac aggaaatgaa ttatttgtat
     5881 caaaaaaata aatagaaagg aaggatcatt gtgcaggata cagtaaaaag gaaaatcgaa
     5941 ttagaaaaaa agcaacttag tttgaaaaac atgtatttca atcgttatct aatcgtacgt
     6001 tacctgactg cctttttctt tttcatgaac atgcaatgga tgattctgct tctatcagct
     6061 aaaagtttag gaagtagttt accgatgatt ctgattttag ctattttgcc tgcagtagga
     6121 gaacaagtaa agctttatcg aaaacaccaa acgaacgttc catggacaaa gtggtatttt
     6181 ttgttccaga gtgtctttaa tttattagtg attccagtgt tgtttacctc aggatttaca
     6241 ttcttgtatc cttttatggc aaataacaat ggaggacagt tatttgtttt cattcttgtt
     6301 gtaagcggta tttttgccag tgcatttata cagtatcgtt taaagaaaat ttcactcaac
     6361 caagaccaac agtatatccg tattaaacaa tatgaaaaag cgttatattt aggaaaggag
     6421 aataactaat gtttgatttt ttgcagaaat acctgatggg acctatgggg aaaattgcgc
     6481 aacttaaaat cgttcgggct gtcatggcag cggggatggc ttctattcct ttcacgattg
     6541 taggctcgat gtttttggtt ttaaatattt tgccattacc gttcccattt ttagaaggat
     6601 tttttaatgc aacttttttc aaagttagtg acttgtacat gatcgtcaat acaatgacga
     6661 tggggatttt atctatttac tttgccattg tgtttgctta tgaattaacg tcaattgaac
     6721 gagatgaaca aaaattaaat gttaatccgc tcacgggggc attactatct gtttttgcat
     6781 tctttatgtg tatccctgaa ttgatcatga ctgatggtaa aatcagcttg attgcttcta
     6841 tcaatgagac agaaactgta gtaaatggta ttaggatggg ctcttttgtc gaacgtttag
     6901 gaacttcagg aatctttaca gctattatta tgtcgattat tgcggtcgaa ttgtattgta
     6961 tgtgtgtcaa gagaaattgg gtcataaaaa tgccagatgt tgttccgcca ggagtttctc
     7021 gttctttcac tgctctgatc ccaacatttg tcattgcgtt tgtggtgatg atcatcaatg
     7081 gattattagt tgcactagga acggatatct tcaaaatgat tgctatccca tttgggtttg
     7141 ttacgcagtt gacgaataca tggcttggtg tcatggtgat ttatttcttg atccatgcat
     7201 tgtggatcgt agggatccat ggagcgaata tcatcacttc tttcttgacc ccgatcgtat
     7261 tagctaatat ggcagctaac gcacaaggcg caaattatcc gttggcagga gaattcaaca
     7321 attcttatgt aaccgttggt ggatcaggtg cgactttagg attgatcatc tttattgcat
     7381 tcctcgcgaa atctgatcag ctgaaagtgt taggaaaagc ctcacttgta ccaggattat
     7441 tcaatatcaa tgaaccaatc attttcggga tgccaatcgt ctacaatccc tatttagcgg
     7501 ttccgttttt cttagctccg atggcttctg ctacactcgc ttattttgcc attcggctgg
     7561 aaatcgtcaa accgatgctt gcacagatgc cgtggccttc accagtcggg atcggagcat
     7621 ttgttggtag tggtggtgat tggaaagctg ctgtgttagc agtcatttgt gcaatcatcg
     7681 cattcattat ctggttccca tttatcaaat tctatgataa taaattatta aatgaagaaa
     7741 gagaaaaggc agcagaatta gctagtgaaa agttaaaatg atttctaaga aaaaaggaac
     7801 tgtgacaaaa aatcacagtc cctttttttc ttagaaatgg gaaaccacta gtatataaat
     7861 accattattc ttcaatcaac cgcttcacga ttgcataatc cccttcataa ggttcatcta
     7921 caccattgat tttttgatag ggatccacgc cttttcccgc aataacgact gaatcttgcg
     7981 gagcgctttc tgctaaagcg cgtcgaatcg cttcaggacg atccatttca taatgaacga
     8041 tcaaatctgg attagtaatt gcttcattga tttcttccgc gatttttttc ggatcttcaa
     8101 atgctgggtc atctgccgtc aaaaaggcga tgtcagctgt ttctgatagc acttttccaa
     8161 aatcatgtcg acgggagatt gctttgtttc ctgggctgcc taatacaaca attacacggc
     8221 catctggatg ttcatttttg gcaaattcca gcaatgtttt caagcttaga taattatgtg
     8281 catagtccac atagacatgc gctccattgg attggatcaa ttgatccatt cggcctggta
     8341 cacgagcttc ttttaatccg tcttgtgcat cttgactgga ggcacctgtt agtgctgcgg
     8401 caatgatcgc actggctgca ttttcttggt tgaatcctcc agccagcaaa atatcataag
     8461 cagtatcgca gatagctaag cgatcttcat gagaagataa agtaaaaccg tgagtacctt
     8521 tatctgaacg gatcacttga taattgcttt cttccgaacg accataagtg atcgttggaa
     8581 tctggaatag atcggctgtt tccctaagta aatcaaaata gtcactttca tgatttaaaa
     8641 caactgtttt tgaattcaag atcaattgtc gcttgcaata gaaatagtca tcaaatgtcg
     8701 gatgttcgat cggactgata tggtcaggcg agatattcaa gaagattccg acatctaaag
     8761 tcaagccgta tacgcgttgt gttttgtaag cttgtgaaga aacttccatc actagatgag
     8821 tcataccatt ttcaactgct tctgacatca tacgatataa atctaatgac tcaggcgttg
     8881 tcaaatggga tttgaaatat gttttgccat ctaacgttgt attcatagta gaaagcaatg
     8941 ctgttttttt atttgttgtg tgatccaaga ttgcttttgt aaagtacgca gcagttgttt
     9001 taccttttgt tccagtgaat ccgatcactt tcaatttatt ttgcggatag tcgtaaaaag
     9061 ccatagcaag aagcgccatt gctttacgga tatccgttac gatgattcct actgctgaat
     9121 tttcgtatgg ttgttctgat acataatatt gaataccctg ttcgattgct gaatccaaat
     9181 attcttcttt gaaattcatt cctttacaga aaaacaaagt agaagcatca gcttttcttg
     9241 aatcataact taactgaaga aattcagctt tttctggtac atcaagatgc cagcctcttg
     9301 ttgaaacaaa ttcttttaat agattttctt ttaatagtaa atgacggatg tcttctaaag
     9361 agaagctcat tgattgatcc ctcgctttat tcaatttctt ggtttattat agcacactct
     9421 ttttaatata tcgtttgttt ccgctatgac aaaatccagc tttattcaaa ttttcttgac
     9481 acaggggaca agcggatgag tattttcata aacaatgaac tgactgtaat agataggaga
     9541 acgaatagtg tctccaacaa tccaaaaaca taataattca aaaagacgat aagactattg
     9601 gtaagtaaaa gtccttgcgg cattggaagc cgaaaaaatt tgtggaaaat aatcggcggt
     9661 atcgttatac cgccatttga ggccccgact gtgtacaatg tgtaaacccc aagactgaac
     9721 aaaagacttc ctgaaatcag tgaaaagaaa tgtgaggaga tcatttccac ttttggaaca
     9781 atctctaaaa caacaggaaa aagcagactt cccgctacag tcttaaaaaa tactgatttt
     9841 cctaatagga cagcggctag aagcagcatc ataagattga tgctccaaac agtaactgag
     9901 cgttggatag aaaaggccgt ttcaactaaa tgtccgatgg cgcccactcc ggcggaagct
     9961 atatcgtgag ggagcaagaa ccaattcaat ccaactgtga taaagaaaag acctaaaaat
    10021 ataacgggta gtttttttat ttcttgtgtc attgatatct cctataaatg ttagccataa
    10081 aaggctgtat atttctttac tttaccaaaa aaacgaaacc gaattcaaaa aaacaattgt
    10141 tcttataaaa gttatataaa atcgattgcc agtttctgtt ttaccaatta aaatgatagt
    10201 aatgttttgt agaaagttgg aatctgaccg atggataatc aaagaaaacc agcattagat
    10261 caattaacac cgcaagaaaa aatggcacga ggctctgctt ggatgaccgc cagtaatatc
    10321 atttcaagat tgctaggcgc tgtctatatc attccctggt atgcttggat gggcgaaaat
    10381 gctaaggctg ccaatggatt attcaatatg ggatacaata tatatgcatt gtttctactg
    10441 atctctacag caggaatacc tgctgcgatt gcaaaacaaa ctgcacgcta taattcattg
    10501 aatgaatatg gcacttcacg acgattattt atccgtgcat tacagatgat gggcgggcta
    10561 ggcctgttgt ttgctttgtt catgtacatc gcctctcctt ggctagctca tgcttctggt
    10621 ggcggagaag aactgattcc aacgatgcgt tctttgagta tcgctgtatt ggtttttcct
    10681 tgtatgagtg tgatacgagg gtattttcaa ggcaatcaag aaatgatgcc ttatgcgctg
    10741 tcgcagattg tagaacaggt ggcacgtatt ttttatatgc tattggctac attcatcatc
    10801 atgaaagtca tggatggtga ctatgtgacg gcggtcacgc aatcaacttt cgcggcattt
    10861 atcggtatgc tagcaagtat tcttgtcctt ttgtattttt tgaagaaaca tcaagcgtat
    10921 acatcggcgt ttattcacta cagcgaaaac aaaataaata ttgcaacgaa ggaattgttg
    10981 ttagataccg ttaaagaagc gattccgttt attattgtgg gttcaggggt aacgatcttc
    11041 aaattagtcg atcagttcac ttttatgaag atcatgtctg catccaccga gtattccaat
    11101 gcacagttac tggatctttt ttcgattttt agtgccaatc cagataagtt gacgatggta
    11161 gttattgcat tggcaacatc gatcgcgtct actgggttac cgttgattac agaagctgtt
    11221 acgttgaaag atcgagtagg tctggcaaaa ttgacaagcg gaaatttaca gttgttttca
    11281 ttttttatgt ttccggcgac atttggtgtt atgttacttg cctatccgct aaatacatta
    11341 ttttatacac cggattctct aggaagtaat gtactgatcc aagcaagttt tgtaggactc
    11401 ttcctaggac tatatatgct agtttccaac atgctgcaag gaatgtttga aaacaaggcg
    11461 gcaattaatt atttggttat tgggtttcta gtgaaactcc ttcttcaata cccagccatt
    11521 cgtttatttg aagtatacgg ccctttattg gcgacaatga tcggatttgc tgtgtcttgt
    11581 accttgatct taaagagaat ccatgaagta gcccgcttta aaccaagttt tgtctggcgc
    11641 aggacattgc tgatctttat tcttaccttg attatgcttt tggcttcgtg gatcacaaag
    11701 atgatttttg gtgctttttt aaacgaagat agcaaattcc agtctctatt gttgattctt
    11761 gtagtagcag gtataggggc tttagtgtat ggttatttag ctttgaaaat ccgcttggca
    11821 gaaagactac taggaccagg aatagcgcgt ttacgacata aattaaaaat aaaataagtg
    11881 aatcagaaga gctagattga tgctcttttg aaatggggga aacgcatgcg tttagataag
    11941 tttttagcag atatgggact tggcagccgc aaagaagtca aaggattgat caaaaaagga
    12001 acgatcgaag tcaatggaca agtggtgaaa agcgataaag cgcaagtaaa tgaattcgaa
    12061 gatgcggtta cttatttagg agaaatcatt acgtatcaaa aagattttta ctacattttg
    12121 cataaacctg caggagtcat ttctgctact caggataatc atgatcaaac cgtaatcgat
    12181 ttattggaag accaggatta tcgggaagat ctttttccag tcggccgatt agataaagac
    12241 acagagggcc tcttgatttt aacgaatgac ggggtgtttg cccatcagtt actatcacct
    12301 aaaaaacatg tggagaaaga atatctagct gaggttagcg gtataatgac agaagaagat
    12361 atccgtttat ttgcagaagg actgattatt gatggcgatg agcagacatt gccggcaaaa
    12421 ctccaaattg atcaagtaga tcaagagaca gaaacttcaa ttatccgtct gattttgcat
    12481 gaaggaaagt ttcaccaagt taagcgaatg gtcaaagcag taggaaaaga agtcttatat
    12541 ttaaaaagaa tccgtatggg aaaattttgg ctgcctaaag atttgaataa agggcaatat
    12601 cgacccatga ccaaagaaga gctagaacaa gtgagagaaa aataattgaa tggatagcta
    12661 aaagaataag cagagtagtt gtagcgccat ctgaaaagca gacttgtccg tctgactttc
    12721 ggatggcttt tttgtgaaat ttcggcttat ttccgtagaa gctacttctg gaacaccgtt
    12781 tgttcggaat aagggactgt gacaagactt ttgttacagt ccccattgtt ccttgtgact
    12841 cagagttaga tagtaaggac acgatctccc taatactcag gccaaaacgc tgaattcaca
    12901 acctctgata aacggtgttc aatcagctga ccctcggtat tagctcaaaa aacggcaaaa
    12961 tatgaggaac tattttcccg tttttttctc taatactcag gccaaaacgc tgatttcaca
    13021 acctctccta tactttgttt cattttccct atactttgtt tatttattct cattattgaa
    13081 agcgctataa ttacgttgcg aatgaatcga aaggggtttt tagatgaaaa aacgaaaggg
    13141 gttcaatcat ttttttatga atctatggcg ttataaagca cttgtcctga tggctgtacc
    13201 gggtatgctt tggatgattt ttttctttta catacctgta atggcgaatg tcgtagcatt
    13261 caaaaatttt catatttcag cagatgggtt cttggctagc ttgagggaaa gtccttgggt
    13321 gggttgggaa aatttcaaat ttttattttc ttcggatcaa gcatttctca tcactaaaaa
    13381 tacaatttta tataatgtag catttatcct tttgaatctg ctgatctcag tcgtatttgc
    13441 aatcattatg agcgagttga gaaataaacg actcgttaaa gtttatcaaa cgatgtcctt
    13501 actaccttat tttctatctt gggtcattat cagttacttt gtttacgctt ttttaagtcc
    13561 tgacaaagga atattcaatc agtggatcac tggacatgga ggagaagctg tcaattggta
    13621 taatgaaccg aaatattggc cgtttatctt ggtgttcatt ggtacatgga aagggattgg
    13681 ttataacagc attatttact ttgcatctgt tatgggaatc gatccgactt attatgaagc
    13741 tgctatggtt gatggagcta gcaaatggca gcagatcaaa catgtgacga taccacaact
    13801 tattccacta atgacgattt taacgatttt agccgtagga aacattttcc gagctgattt
    13861 tggcctgttt tataacattc ctaggaattc cggtgcatta tatgatgtga ctcaagtttt
    13921 ggatacgtat atctacaatg gcctgacatc cacaggagat tttggtatga cggctgctgc
    13981 aggactttac caatcagttg tcggctttgt cttgttgatg atcacaaata cgatcgcccg
    14041 acgttttgat agcgattctg cattattcta aggaggaaaa aaatgaaaaa aaagaaagtg
    14101 gagagagtcc aagtccgctc tttcaataag acggctaatt ttttctctaa tataatgatt
    14161 gcactctttg ctatttcctg tattttgcca tttatatttg ttatcgccat ctcttttacc
    14221 gatgagtcca tattgtcgac tcacgggtac agtttttggc cagaaaagtt cagtatattt
    14281 ggttatacgt acttgttcga ccagatgcag gataaaattt tccaagcgct tttcgtcact
    14341 gtacttgtta ctgttttagg tacactgatc aatagcacgg ctacttcttt atatgcttat
    14401 gcgatttcac ggtcaaactt tccattccgt cgttttttta ccgttttttg tttgattacg
    14461 atgttgttct caccagggat ggtggccaat tatcttgtta tgacaaatct tcttcagtta
    14521 aaagatacga tttgggcatt gatcttgcca atggctgtca gtcccttcaa tattattgtg
    14581 atgcgcacat tctttaaacg ttcggtctct gattcgatta ttgaatcggc acggatcgat
    14641 ggagctagcg aactgcgaat atttgttcag atcgttttac cgttagctgt tccaggtatt
    14701 gcgacaatca gtttatttgc cgcattgggt tactggaatg actggttcaa tgctttacta
    14761 tacatccaag atgataagct agttccacta cagtatcttt tgatgaaaat ccaaagtaat
    14821 attcaatatc tgacacaaaa ttcaggagca ggaagccaat tgacaggcgg attagcctca
    14881 gttccaggag aatctgccag aatggcgatc gtagtcatct cgacgttgcc tattgcgatc
    14941 agctatccat ttttccagaa gcattttgtc aaaggtctaa caatcggcgg agtaaaagaa
    15001 taaagaaaca aaaatataaa tcataaaatt aggaggaaga aaaatgaagt tatggaagaa
    15061 actagccttt acaggtgttt cagcgttgtt gttgggaaca ttagcagcat gcggaggttc
    15121 tggttctaaa gaccaggcag aagctagcaa ttcggacact ttgcagatgt atcaaatcgg
    15181 agataaacca gataatttcg atcaattgat ggaagtagca aacaaacgaa tcgaaaaaga
    15241 gatcggtgta aaagtcaata tcaattacat tggctggggc gattacgaaa agaaaatgaa
    15301 cgtcatcatt tcttccgggg aaaattatga tatcgccttt gcgaacaact atgtttccaa
    15361 tgcccaaaaa ggagcctttg ctgatttgac tgaattagcg cctaagtacg ctgaaaaagc
    15421 ttataatgat ttagatgaag catatattaa aggaaatctg gtcaatggaa aattatatgc
    15481 tttcccagtc aatggaaatg tctttgctca acaagtactt acttttaaca aagctttact
    15541 agataaatac gatctttcaa ttgatggaat ccaatcttac gctgatgcag aaaaagtctt
    15601 gaaggaattc catgaaaaag aaccaaacac ggcagctttt gccattggac aaggcttcaa
    15661 agtccaaggg aactttgatt atcctttagg gaatacgtta ccatttgcta ttgatctgga
    15721 tggagatgat tcgaaaatca tcaaccaata cgataatgaa acgtatatcg gactgttacg
    15781 tacaatgcat agctggtaca aacaaggact cattccaagt gacgctgcaa cgagcaataa
    15841 ggattatcca ctagaaggaa atacttggct aatgcgtgga gaaacacaag gaccgtatga
    15901 ttatggcgat acaattttga caaatgcagc aaaacaagaa cttgtctcaa aagcaattac
    15961 tgttccacta aaatctacag ctcaagcaca aatggcaaat tttgtcgtat caaatacttc
    16021 aaaaaataaa gaaaaatcag tagaacttct agggctgctt aacagtgatc cagaattatt
    16081 gaatgggctt gtttggggga tcgagggaga agcatgggaa aaagtcgatg gttcagatga
    16141 taaaatcaaa ttgctagatg gttatcagcc aaatacacat atgtctgctt ggaatacagg
    16201 aaacaacaag attctatata cacaagagtc tattacggat gacatgattg ccaaacgtga
    16261 tcaatcgatt gctgatgcag aaacttcacc gattttagga ttcagcttca acactgacag
    16321 tgtcaaaaca gaattaagta atatttctaa tgtcatgaat caatatttag atggattgaa
    16381 tacagggact gttgatccag atgaaacatt accgaaattg aaagacgctt tggacaaggc
    16441 tggctatgat aaggtattga aagaaatgca aaaacaatat gatgagttcc gacaagaata
    16501 ataatgaata aagacaaagg ggttgtgaca aaagacgtgt cacaacctct tgttccgaat
    16561 aaacggtgtt caaaagccag tttctcggta ttaagctaaa tatatgtaaa aatgtggaaa
    16621 gccatattca caaaattttt cttactactc gaaactaagc ggctatttca caaactcttg
    16681 gtaaacggtg ttcaatcagc taaccctcgg tattcgctca caaaacgaca aaatatgagg
    16741 aactattttt ccgtttgttt ctctaataat caggtcaagg tgctgattgc ccaacctttt
    16801 tttgtataat gagaaagtat aaacttaatg tttggaggag aagatatgtt agggaaggtt
    16861 ttggaagagt tatttatccg gatctgggtc attataaaac taaccttgta tttctggata
    16921 tatacatttg ccggcgggat catctttgga ttaggtgcgg catggaaaac agtcaatgaa
    16981 ctattttatt tgtacggatt cgagtataaa gaaatcacaa taaaaagagg ctggaatata
    17041 tataaaagaa attttttaag aggcaatctg ctatttagtt tatttttatc tggtactgct
    17101 ttattgagtt acaatttata tttatctgtt caaatcaaag ggctcatttt tttagctatt
    17161 gattttattt tactttttgc cttgctctgc ctatttgcta cttatcaata cagtatgatt
    17221 ttagatagtg aatatacgat ctctgttcct aatctgctaa agctaagttt tatttcggtt
    17281 ttttccagct tttcgtcttt tctaaaaata attattggta gcggtataat tttaggcgtg
    17341 acttggcaat tcaaaggatt gatcctgttt ggtgtcattg gtcttttgac ggtttggaat
    17401 ggtacgatga caacacattg gcgtgaagaa ttagataaac agttggaaag ttatgaataa
    17461 gtttcggatt ctattttcaa aaggaacctt actaaatcgt ctgttgcgga aatacgcggt
    17521 tatcatgatc ggtgtaacga tgactgctac cgttattttt agtatccata cttgggaaca
    17581 aaatcaaaaa caggcagaaa acatgacaag tgatgccgtt caaagcacaa gcagaatgct
    17641 gaatgataaa acaaccttga gtaggatcat caaaaaccag cttgtaggga attccgaaaa
    17701 gatcgaaaat gtgacgacct acttaacaaa acccatagat cagtatctga tgtatgtata
    17761 cgaacagcaa aacagtaccg atgaattagt ttctttccca aatcaaatca aagatctcta
    17821 cgcaaattat gaagaactaa gtgcgatata tatcgtgttg aatcaactac cggagtatta
    17881 tgaatcttct agagaaaaca aaggtgggga aataaaaaag gggacaccaa aattactaga
    17941 cgccttttat atcaagttgc ctatcacaca aggaggagct gagtcaggaa gtatttttat
    18001 tggttttcaa aagaaagaac tagatatgat tttagaaaat ctaacgtcat tcaatggact
    18061 ctctttatac atgatttctg gaacgacaaa tcgactatac acattccatg ataataaaat
    18121 agctaaagaa acgtttgaaa gacaagaaat gatcatcaca gagagtctga agaaaaattc
    18181 acaattgccg attgacgatc tggaaaaaaa caattttgtt caacaccaag aactgtctga
    18241 tgattatcgt atattagctg tactagataa aaaaagtgta aaaatcgaaa cgggaaaaaa
    18301 tcttgccccg ctgatcattg gtatcattat tttagacaat atactgctta tctttcttta
    18361 taaaacattc aaacgatatt cacagcaagt atctatcgtc atgcaggcca tggatcaaac
    18421 agcagcaggg aatttagaga cgcggatcga cataacaaac acggaatatg aactgaagga
    18481 actttcaatc ggtatcaacg aaatgttgga tagcatcaat cagtttgtag aagacatcta
    18541 caaattagaa atcaaacagc aagacgcaca tatgcgggcg cttcaagcac agatcaatcc
    18601 acacttttta tataatacat tagaatatat ccgaatgtat gcaatcagcg aaggaagtga
    18661 agaattagca gatgttgtgt atgcgttttc cgctttgctt cgaaacaata cgaatcaaga
    18721 gaaaacgatc actttaaaag aagaactgga cttttgcgaa aaatatgtct atttgtatca
    18781 aatgcgttat cctaatcgag tagcctatca ttttatgatc gatcctgatt tggaaaagat
    18841 cgaagtacct aaatttgtga tccagccatt agttgaaaat tattttaaac acggtattga
    18901 ttttactcga ttcgataatg cgctaagtgt caaagtcttg caggaaggca aacgggtaag
    18961 gatcatcatc aaagataatg gaaaagggat gactgaaaaa cggctaaaac agattgaaga
    19021 aaaactgtct catcctaaag tggaacttca cggttctatc ggtctgcaaa acgtgaatga
    19081 acgtttacgt gccagcttcg gcagcagtta ttatatgtcg cttgagaata atgagacagg
    19141 tggactgacc gtttctatta cattcaagga gggatgagcg tgtatcaagt gttattggta
    19201 gatgatgaat acatgatttt gaatgggtta aaaaagataa ttgattggca aagtttaggc
    19261 tttcaaatag tagcaacagc agagaatgcc aaagaaggac tagctgtact tgaacagcga
    19321 cagattgatt tagtagtaac ggatgtgaca atgccagaaa taaatggact ggaatttatt
    19381 gaagcggctc aaaaagaacg tcataatttt gaatttatga ttttatcagg ataccaagaa
    19441 ttcgattatt tgaaaggagg tatgcaatta ggcgccgtga attatttgat gaaacccgtg
    19501 aataagttcg aattggttga aagcctcaag aaaatcaaaa cacggttaga tcagcaaaat
    19561 gaacaaaaaa atcaacaaga aatctatcaa gaactgttat tcagtcaatg gttgaatgaa
    19621 gaattggatg aaataagtga agaagaaata ataggacaaa taagtgagaa gcagcatagg
    19681 atagtattga ttcaactggc aagaactcat gatactctta tcaatagatg gttgcaagaa
    19741 cggcaacaaa tcttttacta tcaacgaaat tacggagacc gtgtattgat cacgttgttg
    19801 ttggaggcag atgaagttga tggcttctgt tgttttgttc aagaaaactt tcctgatcag
    19861 gaatggctga tcagtatcgg ggaagagaca gattctttgg acaaaatccc tgaaacattc
    19921 caacaagcga aagacaatct acagttgcat caattttatg gagataaaga cgagcatgtt
    19981 ttttacgcag tacaagcaga aacaaaagat caaaccatcg atttttcaag tttcagacgc
    20041 gtgctgcaaa ataaacaatt ggaagtcgct caaaaaatga tcactgattt ttttgaacag
    20101 tttcagttag cagccatgat gccggaagat atacgatatt ccagtttttt actgtttatg
    20161 gagattcaac gggaattgat tgatctggaa gatgaggaat atttacaagg aatcgaaaaa
    20221 atccatcagg caaaaacggt gcaagaactt cagcagctac ttctgtcatt catcaaaaag
    20281 catcagagac agaaaaagta cagtgacaat gtggaaaaag taatcgtaat cctgcaccag
    20341 cattatcaag aaccacttac actcaaagaa gtgtcagaaa acctgcattt aaatgtcatg
    20401 tatctaggac agctgttcaa aaaagaaacg aaaaaaagtt tttcagctta tttgaaccat
    20461 ttacgtatgg aaaaagcgaa acaactgctt ttgcacagta atcaaaacat caatgagata
    20521 gcaagtgaga ttggctacaa caacaccacg tatttctcta aattattcaa gaaaatcgtc
    20581 ggcagatccc ctaaagagta ccgagaaaac agtggagaat cataaaaaaa aaagccaatg
    20641 taatgaaata acttataaaa aattgtctag aaatctaatt ttgggctgtt cttattactt
    20701 gaggcaaggc agctttttca tgacctctcg ataaacggag ttcaaaagcc agtttctcgg
    20761 tattaagcca aatttatgca aaaatgtgga aagccatttt cacaaaattt ttcttaatac
    20821 tcgaaactaa acagcttttt cacgacctct ccactaaatg gtgttcaatc agctgaccct
    20881 cggtattagc tcaaaaaatg gcaaaatatg aggaactatt ttgccatttg tctctctaat
    20941 actcaggtca gaacgctgat ttcacaacct ctcaataaac ggtgttcaaa agcttgcatc
    21001 tgcggtaata agaccaacca aacgaaaaat atgaggatct atttttgctt ggctgttctt
    21061 attacttgat gcaggacagc tttttcacaa cctcttgtta attatagttt gataaggaaa
    21121 aaggcaaatc ttttgcttga tatttcttag ggtgagggat gatccctaat tggtaagaga
    21181 tcgtgccgcc tttcagcaaa tcttgatggg taaaatataa tttcgtatat tctctgtcca
    21241 tccgtttgat tttatggata aattgttgct gcggccgatt aggcgttgct tcaatcgtca
    21301 attcctttcc atttgacaaa agcaaaacag ccttgtcaat taatggcata ccgataacat
    21361 attcaccggt tccaggcgtg acaggataaa atcccagact attgaagata taccaagcgg
    21421 ccatacttcc attgtcctca tctccagggt aacccattgg agaatcgtcg aaggtctgag
    21481 tcatcaactg tttaagcagt ggctgtgcca tttcaggttg tcctatataa ctgaacaagt
    21541 aaggatagtg aaaacttggc tggtttgaaa tagctaattg tccaaattct atcgcggcca
    21601 tctcactcat ttcgtggatc tcaaaaccat atcctcctgg gtcaaacgtt gggggctgat
    21661 tgcacagctc aatgagtttt tctttatatc tctcactgcc accatatttt ccgatcagtc
    21721 ctgaaaaatc gtgataaaca gcaaagctgc tttgccaagc acttccttct gcataatctt
    21781 gtccccaacg attagctgaa aatggttctc tgaacttgcc atctttatct tttgaacgca
    21841 taaatcctga ctcatagtca aagatatttt gatagttcaa tgattgctgc tgatatttct
    21901 tcgtcatttc ctcttcttct agtaccttgg caacttggct aatacaaaaa tcgctataag
    21961 catagtctaa tgtgtgattg actgattcgt ggtagtgatt aggaacatag ccatatgtca
    22021 agtaatcttc tgttccttgg cgtccataat ttggatgttt gctttgaacc gtagcacctt
    22081 tttccattgc cgttagaaat tcaggcatca agtctcgtcg gatatctttt acagcagcat
    22141 ctgcaatgac cgcatcgatc aatgtcccag gcataagtcc acgttcatca ggagacagcc
    22201 attttggcaa atagccactt tctctatagc tgttcaaaaa accttccagc atttcttcgt
    22261 atttttctac agcaatcaaa gaataaagag gataaaccgt tttatacgta tcccaaaacc
    22321 cattatttgt atagagaaca ccaggtttta tagatcgact agtcgtatca tagtggattt
    22381 tttgcccact aggatcaatt tcataaaatg tttgtggaaa taaaaacacc cgatataaat
    22441 tatgataaaa cgtccgcaat tgttgttgat catggtgtgt gagctgtata cgatcaaaat
    22501 aggactgcca ttgttcttga ctgtgagcaa ggtaagtctc tttgctttgg ttttgttcta
    22561 gttccaggtt ataagctgct tgttccgagc tgataaaaga tgtcccaaat cggatagttt
    22621 gtttttttgt ctgttcaaaa tacaacggga tcgagtcgct atttttgttg gaaacagcta
    22681 actcatcaat tgttaaagga tattcaaatc tcaatataaa ataaaaagaa aaatcaggat
    22741 cttctgaacc agcaaaatgt gtgatttttc cttccactgt gtaaggatct ataacaaaga
    22801 gctgatggcg tcccggaaag gataaaagta aaccgctgtc atttttgctg taatcaatag
    22861 ataagattcc gccatacatg ctaggtatca atgtagaaca gatgccataa cgtaattgac
    22921 agatcgacag atgagtcggg caaaatatac tttcttctgg gcggtaagaa ctttgagcat
    22981 ggaaaagggt gttctcctgt agttttccat tgatcggcgt aaacagcata tgactgaaat
    23041 cacccatcca aggacttggt tgatgggtaa gacggtagcc ttgaaaaacg cggtcatcag
    23101 gatgaaacca ccagctgccg ttttgatccg tagtttgcgg tgcaaaataa ttcatcccaa
    23161 aaggaacgcc agtataaggc tggcagttcc cattagagaa atttggctga ttcgctgttg
    23221 catgtctagt atctatttga ccgatattca ttttatttct cctttgttga ttgtcttttg
    23281 atgaatgaaa ctggaaattt actatcggat ggtcgatctt ttgtctctaa ccaagtgacc
    23341 aaagcatctc ccgcaagctt acctaactgt tcaaaatctt gtgcgatggt tgtcagtggc
    23401 gggtcaacaa gagctgctgc ttggatatca tcaaatccga taattgaaaa atcttcaggg
    23461 atatgataac catgctgtct caagagattc atggtctgga tagcgacaac atcgttttca
    23521 caaacaaaag cagttacttc atacttagtg atataagaaa gcaattcatc taatgtcgcg
    23581 cttttgtcat ccagtgaagt gtggaaagtc aaaccagctt tgtccaatgc ttcaaggtaa
    23641 ccaaggtaac gctgtcgaac ggattgtgga tgagtctgcg taccaaacaa ataagcgatt
    23701 tttgaatgtc cctgttcgat caaataagag gcagcaagcg caccgccttg gaaattatcg
    23761 gaaagaacgg taggaaaagg taactcatag atttttttat ctaatatgac gacagggaat
    23821 tctttcaatg aaagctcaaa aagtaagtca agatgttgtt ctgtatcaag agcataataa
    23881 atcaatccgt caaattcatt gattagctct tttgctgttt tattttgtag aaagtcaagc
    23941 gtcgtcatca tgacatcaat ctgtttatct tgcatcacag ggttcaatcc cttgctaaaa
    24001 tcaccaacag acaaatcagc gacatatgga agaagaaaca gaatccgtcg tgtttttgta
    24061 ggagaagcaa gaatctgttc cggagaagcg gatttaacga aactgccttt cccgcgaacg
    24121 cgataaataa gtcctaattg ctctaattca gtcaatgcac gtttggaagt gattctgctt
    24181 actttatagg tacgtgaaag ttctttttca gttggtagtt ggctgtctac aggtaattca
    24241 ccagttaaaa tagccgtttg caaatcatta aatattgtct ggtacaatgg ttgagtcata
    24301 taaacacctc ttaatgatat atcatattca aataatacca taatggatga aaaagtaaat
    24361 aaaaagatat tttttgaaag cgtagacata attggctgta tgaagtataa tctttaaaga
    24421 tatatcaaat agaaagaagg ttttattagt ggtttataaa gatataccaa aatcggtgca
    24481 gaaatttatg gaagatatca cacaaaaatg tggggatatc catgcggact gggcaaagaa
    24541 ttttacagca gcatttgcca atactctgtt gacaacagtc aaaaagcaaa atgacggaac
    24601 caccttttta ttgacgggag acattccagc gatgtggtta agagactcta ctgcacaagt
    24661 tcgtccttat ttagtgattg caaaagaaga tgaggaatta gctgacatga tcagcgggtt
    24721 agtcaaaaag caattttttt atatcaatat cgatccatat gcgaatgcct tcaacgaaga
    24781 agctaacggt gctggccacc aaacagatca tacaaaaatg aacgattgga tctgggaaag
    24841 aaaatatgaa attgattctt tatgctaccc aatacagttg gcctatcttc tttacaaaaa
    24901 tacaggaaaa actgatcaat tcaatcaatc ttttattgaa ggtatcaaaa aaatcttgga
    24961 cgtgttcaaa acagagcaag atcatgaaca ctctccttat acatttgtac gagacacgac
    25021 aagaaaagaa gatacgctga tcaatgacgg gcgaggtgca aaaacagctt ttacaggaat
    25081 gacatggtct ggtttccgtc ctagcgatga tgcttgccgt tatggatatc tggtaccatc
    25141 caatatgttt gcggtggtcg tgttaggtta tgtggaagaa atttttcaaa cgatactcga
    25201 tgataaagaa attgtacagc aaacacagaa attgaagaaa gagatccaag aggggattca
    25261 gaatcacgga cgaacggtta atcaaaaagg gcaaacgatt tatgcatatg aagtagatgg
    25321 aatgggaaac gccacagtca tggatgacag taatgtgccc aatctgatcg ccgcacctta
    25381 cttgggatat tgttctgaac aagaggaaga ttatctgcaa acaagaagaa cattgttgag
    25441 taaagaaaat ccatatttct atgaaggaaa gtacgcaaaa ggaattggat cctcccatac
    25501 gccagaaaaa tacgtttggc cgattgcatt agctatggaa ggaatgacaa cgtcagacaa
    25561 atctgaaaaa gagcggatat tgaatttact tgtagcaact gacgcaggaa cacaccttat
    25621 gcacgaagga ttcgatgtga acaatcctga aaattatacg agagaatggt tttcttgggc
    25681 aaatatgatg ttttgcgaat tagtcatgga ttactttgat attagagtag aaaagtagga
    25741 ggtatcgtaa atgaaaaaga aagtatatat catttctcat agccactggg atcgtgaatg
    25801 gtacatggct tacgaacagc atcacatgcg actgattgaa ttgatagacg atctactaga
    25861 gctatttgaa gttgatccgt ccttcaacag ttttcatttg gatgggcaaa cgattatttt
    25921 agatgactat cttcaagtaa ggccagaaaa aagacaggca atccaacaag caatcaatga
    25981 aggaaaattg agaattggac cattttatat cttgcaagat gattttctta tcagctcgga
    26041 atcgaacgtg agaaatatgc tgattggcat ggaagaaagc cgtaaatggg gaacccctgt
    26101 catgttaggc tattttcccg atacatttgg aaatatggga cagacgcctc aattaatgaa
    26161 acaagctggt atttcagcag cagcgtttgg ccgtggtgta aaaccaattg gctttgataa
    26221 tcaagttttg gaagcagaaa actattcttc ccaatactca gagatgtggt ggaaaggccc
    26281 tgatcaaaca gcaatctttg gtctgctatt tgccaattgg tatagcaacg ggaatgagat
    26341 tccagtagaa aaagaagcag ctcttgcctt ttggaagcaa aaattagcgg atgcagaaca
    26401 atatgcctct acgaaccact tattgatgat gaatggtgtt gatcatcaac cggtacaaaa
    26461 agatatatca aaagcaatcc atctcgcaaa tgaactgttt ccagattacg agtttattca
    26521 ttctaatttt actgactatc tggaagcagt tcaaaaagat gtgccagaag acttaggctc
    26581 agtagaagga gaattgacaa gtcaagaaac ggatggctgg tatactttag ccaatacagc
    26641 atctgctcgg gtttacttaa aacaatggaa taccaaggtc cagcgacagc tagaaaatat
    26701 tacagaacca cttgcgacga tggcttatga agttagtgga aactatcccc atgatcaatt
    26761 agattatgct tggaagacat taatgcaaaa tcatcctcac gacagtattt gcggttgttc
    26821 agtcgattct gtccatcggg aaatgatacc tcgttttgaa aaagcagatg aagttggaaa
    26881 gtatcttgca caagattcct tagaacagct gaccgcagca atcgatacga ccggattccc
    26941 aaaagacagc tttccatttg tcattgtaaa tactgcagga atggataaaa ctggtgaagc
    27001 agaaataacc atcgaattag aaagaaaaag attcgctgaa ggaatacctg aacaactata
    27061 tcaagagtta gaaaatttgc ctaaacgtaa gtatcatgta gaaacaaaaa gtggggccac
    27121 tataccagct attttatctg aagaaactgt ccaatttggt tatgatttgc cgaaagaccg
    27181 tttccgtgtg ccatatatgg caagaatgat caaagtgact ttaccattag aaaacatgcc
    27241 agcattttct tgggaaacat tcgcgcttgt agaaggggaa gcgaaagcag aagaaaagga
    27301 aacaatgatt catcagagtg gacgaatcat cgaaaacggc cctctacatt tgacgattga
    27361 aaaaaatggt accattacaa tggaagatcg caaaaacaaa cgaaagttga ataatctgca
    27421 tatttttgaa gatatcggcg atataggaaa tgagtatatc tttaaacaac ctttctgtga
    27481 tcagccaatc ctatccagta acaaagaaaa ctctgaagta aaagtattag tagatacacc
    27541 ggaaatagca aaaataagta ttctacagga aatggaaatc cctgtttctg cagacgagcg
    27601 tttagaaaaa gaacagcaga tggttgtgga atttcgttat cgaaaagcag aacgatccaa
    27661 agaaaaacga atccttcaaa taaaaacaat catgacaatc agaaaagata gtaaaaaaat
    27721 cgactttgaa acgactctcg acaatcagat gaaagatcat cgcttacgtg tcttgtttcc
    27781 tacaaagtta catgtggaac atcacgaagc agatagtatt tttgaagtgg tgaagcgccc
    27841 aaaccatgtg tctaaaagtt gggaaaaccc cacgaatccg caacatcagc aagcatttgt
    27901 caatattcat gatgaagagt acggtgtaac agtcggaaac tttggtttga atgaatatga
    27961 agtaacagaa gacggacaaa tcgcagtgac gctacttcgc agtgtgggag aactaggcga
    28021 ttggggatat tttccaacac cagaagcaca gtgtctaggt gagcatcggt tcaattacag
    28081 cattgaacta catggaccag aagaaaaatt ctctacttat ttgcatgcat acgcagcaca
    28141 gattcctttt tccactcaac aaatcaaaca tcatgaagga acattgattt caaaacaaca
    28201 atatttaacg ataaaaagtg aaacgtttgc aattacagct ttgaaacgca gcaagtttag
    28261 tgataaagta gtagtaagag gtttcaatat gtctagtcat ttagaaaaat tggaaataac
    28321 taaagacaat ggaaaaactg tcatattgaa tctgcttgaa gaaccaacga agcaagcggt
    28381 tgtcccaata atccaacctt atgagattcg gacaatcgga ttcgaggagg aaaacgaatg
    28441 tatggcggaa tagaagcagg cggaacaaaa tttgtgtgtg cggtttcaga tggtggagaa
    28501 attttagaaa aattaagtat ccctaccaca acaccagaag aaacattgga tcaggtattt
    28561 gaattttttg atcgttatga attgaaggga atcgggattg gctcattcgg cccgattggt
    28621 atcgacaaaa caaaagataa ttacggatac gttttggcaa ctcccaaaaa agggtgggca
    28681 caattcgatt ttcttggcac aatcaaggaa cgctacaata ttcctgctgc ttggacaacg
    28741 gatgtcaatg ctgctgcata tggggaattg aagcaaggag cagcacaagg aaaaaatagt
    28801 tgtatttacc ttaccgtggg aacaggaatc ggtgcaggtg tcgtgatcaa tgaagaaatt
    28861 ttttcaggga tcgcacatcc tgaaatggga catatttggg tgaaacgcca tccagatgac
    28921 cattatgaag gtacttgtcc ttatcataaa gattgtttag aaggattagc agcaggaccg
    28981 tctattgagg cacgcacagg gatcaaaggg caagatctgc cgcaagatca tcctgtttgg
    29041 gctattcagg cttattatat tgctcaagca ctgatcaact atacgttgac gttagcacct
    29101 gaaaagatta ttttaggcgg tggggtaatg aatcaggatc atctccttca aaaaatccgt
    29161 cagcaatttg ttgaattgat gggtggttat atggaaacac ctcaagtaag tgaatatatc
    29221 gttcgttggg gactgccgaa tgaaagtggg attatcggta gtttgctgtt agcagaacac
    29281 gaacatcaaa agtaagcaga caaattacac aaaaagaaca gagtcttatc attatctgct
    29341 gataagactc tgttcttttt tatttctatt cccataatcc aggtaaagct ttaccgacta
    29401 ttttttcttg agtaaatgga tggatcatgt gcagttctaa tgcatggagc atcagtcgtt
    29461 cagctgttct attttggtag agagggtctc caacgatcgg atgtccctta tgagctaaat
    29521 gaactctgat ctggtgtgta cgtccggttt ccaaaacaca atagacttgt gtttgttcag
    29581 aaagtacttt gttgacagtg acatgtgtca aggcgctctg accattttta tcatctacga
    29641 ccctttttct ccgatcatgg cgatctcgtc caattttatt ggtgatggtc atatctttgg
    29701 caatttctcc ccatacgatg gcttgatatc tccgatagat cattttttgt tccaacattc
    29761 ttccaagtat cggcaagaca aatggatttt ttgcaaataa aacggcaccg cttgtttctt
    29821 tgtccaagcg gtggacaacg taaggtcgtt gctgtttagt gtcgagataa gcagctaaat
    29881 gattgagtaa ggtactgttt tctgtcggtt catttggatg agtcttcatt cctgcaggct
    29941 tatccactat aatcaaatgc tcatcttcat ataaaacacg gatgtgcttc gcatctccta
    30001 attgaacttc ttgataatta taatctgttt cttcgaataa caatgtgatc tggtcattgc
    30061 cctttacttc atgatggaac aaagcaggtt gttgattgat ccaaacgttt ttacgtatac
    30121 gcaaaaagtg tcgaaccttt ctaggaacta accattcctt ttcaagcaag tcgcgaattg
    30181 ttgtttcagg atggttcata ggtaaagtga tcgtgatttt cacaagtgta ctcctttcag
    30241 tgcaatcgca gactaattgt accattttta aaacatattt aagaaaaaac ttacattttt
    30301 ctgttcattc ttatgttact ctacttgcac taacgtaaaa aaacatattg aactacaact
    30361 taagcaggaa gaaaacactc tttcactatg gtaaaataag acgattgaat caaatagaca
    30421 ggagaagaag caaatggatt ttcaaagcat tttagaaaag ataaaagctg ctttgatcag
    30481 tttttggcgt tggatcagac catatctcgg acaattccat cgatggcgaa agcgcatctg
    30541 gaaaaaatat catgtgaaca aattgatttt gctgattggt ttgatctgtg tcttagtgac
    30601 aagtatctac ctctttattt tagcaaaaca agcaaatgtc gaaacgttaa aatcaggatt
    30661 aagccaatcg acagtcattt atgataagaa aaacgaagaa gctggcacac tgtacgccca
    30721 aaaaggaaca tatgtagaat taaacgcgat ttctccctat atccaagatg cagtaatctc
    30781 gacagaagat aggaattttt acgagcatca cgggtttgat atcaaaggga ttgcccgtgc
    30841 agcagtccga atggtcttgt ctggcggaac atcagggggc ggaggaagta cgatcactca
    30901 gcagcttgcc aaaaatgcgt atctgacatt agaccaaacg tttgatcgaa aagcgaagga
    30961 attatttttg gcaatcgaga tcgaaaagaa gtacagcaaa gaagaaatct tgaccatgta
    31021 tcttaacaat gcctattttg gcaacggggt atggggtgtc caagacgctt ccagaaagta
    31081 ttttggagta gatgcaacga atgttacgct gtctgaggct gctactttgg caggaatgct
    31141 gaaaggtcct ggtatttata atccgatcga tcacccaaaa aatgcgaatg atcggaaaaa
    31201 cacagtacta agtgtaatgg aagaaaacgg aaaaatcaca aaagaacaag aacaagcaga
    31261 aagccagaca gatatcagcg cgtatcttaa tgacacatac gataattcag attctggtta
    31321 tcgttatcct tattattttg atgcagtgat cgatgaagca gttaacgagt atggtcttga
    31381 tgaagaagat gtcatgaata aaggctataa aatctataca gctttagatc aggattatca
    31441 aaagcaatta gaagctactt atcaaaacag tgcattattc ccagcaaatg cttcagatgg
    31501 tgccatggtc caatctgctt cagtagcttt agatccgaat acaggtggtg tacaagcact
    31561 agtaggacga agaggagatc atgtctttag aggattcagc tttgctacac agatgcgtcg
    31621 ttcaccagga tcaacgatca aaccattaag cgtatataca ccagcactgg aagctggata
    31681 caagccttcc agtatcttga aagacgaacc gcaaagttat tacgatgcgc ataattttga
    31741 cgggacatac caaggagaag taccgatgta tcaagctgtt gcacaaagtt tgaatttgcc
    31801 tactgtatgg cttttgcatg agatcggttt acaaaaagga tatgataaag cagaagaatt
    31861 cggcctgcct ttagcaaaat ctgataagta ttatggctta gcccttggtg gactggaaaa
    31921 aggagtatct ccattgatca tggcgggtgc ttacagtgca tttgccaatg atggtcagat
    31981 gtatacgccg catcttatca cgaaaatcgt tgattcgact ggagcggtga tcgtcgataa
    32041 cacaaacaaa aaaccaaaac aggtcatatc aaaggaaaca gccgatgaaa tgaccagcat
    32101 gcttcttggt acattttcaa atggaacagc ggctgctgcg aatcctgcag gttatacgat
    32161 agcagggaaa acaggaacca cagaaactaa tttcgatgcc acaaaagcaa atgaccaatg
    32221 gatgatcggt tacacgccag acgtagtgat ttcgacatgg atgggttacg aagaatccag
    32281 caagctgcac tatttggaag ggacaagtgg aaatgttgtc gggaaagtct tcaaatcagc
    32341 ggcagaaggc atccttccgt atacttcaaa aacaggattt agtgtagcag atgcctatgc
    32401 cacaggagga caagtggtag ctgcagatca agttggaaac acaggaaatt ctaatggaga
    32461 gtctggaaat tggcaagata acttgaatca atatggtgaa caagcaaaag aagggctgaa
    32521 aaacttcggc gatatggtga aagaaggcgt tcagggaatt ggtgaagcgg ctaaagacct
    32581 ctggcggaaa tatcaaggag agtagcccct ttgaaaacga ataaccccat gttacaatag
    32641 agagtaacta ctaaaagaaa agagggcata acatgtcaaa catctacgat agcgcgaatc
    32701 aaatcgaacg tgagatccgt gaattaccag aattcaaagc gttgaaagaa gcgtacgaga
    32761 aagtacaagc aaacgaagaa gcacacaaac tgttcaaaga cttccaagcg atgcaaatcg
    32821 aattacaaga aaaacaaatg agtggacaag agttcagcga cgaagatgca atgaaagcac
    32881 aagaaatggc tgtgaaaatc caatcagaag aagtaatcaa tgacttgatg caaaaagagc
    32941 aaggcttcag tacaatcatc aatgacttga accgtatcat catgacacca gttcgcgacc
    33001 tttacagcga ataaaactat tttatgaaac aacagagggt gtgaaagaga cgttcggcct
    33061 tgagcgatga caaaattgct tcttattgcc gataggctgt ctcttgaaca ccatttacca
    33121 agaggtcgtg agcctaccgt ttaactctga gttacaagga acaatttcaa aaaacagctt
    33181 ctcatgtttg atgactattg tgacttgtga ccgaggagtt ggcaggagaa caccgtttat
    33241 tcagaaatag gagctacgac aaaagtcttg tcatagctcc tattttttgt cattcatttt
    33301 tcaagcggta gaaatagcct ttttgagcta acagtttttc gtaagtacct atttcaacga
    33361 tttttccttc atcgatcaca acgattttat ctgcctcttt gatcgttgaa agccgatgag
    33421 ccacaataaa agtagtgggt gtttctgtca ggtaattcag ggcttgctgg atttttttct
    33481 ctgactggtt atctaaagct gaggttgctt catctagcaa aatgattttt ggctgacgta
    33541 tcaacgctcg tgcaatggag atacgttgct tttggccacc agacagcttg ttgccatgtt
    33601 cgcctactaa ggtatccaga ccatcaggaa gctggtcaat cagtgaagaa agttgcgcag
    33661 cttcgatgac ttcatctaaa cgttcttttg atacgttttt caagccataa gtgatgttct
    33721 ctttgatcga agcggagaac aacaaagtgg tttgaggaac aacggctaaa taatttcgca
    33781 cacttcgcat atccagttca tccaaaggct gatcatctag aaaaattttt cctgaagtcg
    33841 gctggataaa tccaatcaat aagttaagga gtgtagattt tccagagcca gatggcccaa
    33901 caaaagcaat tgtttctcca gctttcacct ctagagaaaa atgatcgata atcggtttga
    33961 gtgagtccgg ataaagaaaa gaaacatcct caaaacgaaa atttccatcc aaatgttgga
    34021 tttttttctt accgtgataa gtttctacat cgccagcaat caacagttcg ccaatagaag
    34081 tgatagattc catgcctttt gaaatcgtag gaatcagcgt gatcattcca gaaacggaat
    34141 tgacgatcgt cgtgaaatac gtctgataca tcacgacatc gccgggttgg atgcgccctt
    34201 gtaaagctaa tatcccagtg aaaatcaaac aaatcagctg aaatatctga aaactagccc
    34261 agctgactga tccgaaaaca gattgcagga tatctaagtg gaatcctttt tcatagattt
    34321 gagtaaaatg cttatttaag cgagttgttt cgtgtttttc taacccatga gctcgagcaa
    34381 tcggtgctaa ttcgatcact tcgatcactt ttgcagaagt ctcttccatt tcttgcctga
    34441 agtctgagtt ggactgtctg atccttttac ggaaaaagag agtaacgaat gcggcgagag
    34501 gaacagtcaa taagaaaaac atgaaaacaa caggactttt ataaagcgtg atacctaaag
    34561 ctacgaataa attgacagcg atatttaatc cgctgacaaa tacttgagag gacaacgttt
    34621 ggatagcttc tacatcacgg atgatctttg actggattcg tccagattgc aattcttttt
    34681 gataaggaat agatagttct tggattttct tgataagggt cgctcttagt ccagcttcta
    34741 cttgacggat cgaagtgcta tggtatttta catgaaaata attcgtcaat atattttgac
    34801 caatcagaca agccatcaaa aaagcgttga aataaatggc ctgcaactga gaagaatctt
    34861 tcgatgaagc tgcattgatt acattggcaa tagcgatcgg cattaaccaa gatggaagat
    34921 gtttgataat aaaaaagagt cctgacatgg caaaacgcca ataatttccc tgataaagat
    34981 gcagcaatgt ctgaaaagca tttgcatgat atttttgata acttttctgt attcgttcct
    35041 ccataatctt ctccttaaca atcttggtaa ataaactgca agtgttctat tgcttcagga
    35101 acataaatct caggagtagc ttcaagagtg gcgtacatta gaggacgctc atatttgata
    35161 taatgcagta ccgggcggaa atctaaacag cccttgccaa caggtaccat gcggatcttt
    35221 ccattttcca tgatatagtc tttgagatga agcgctgtaa tataaccatg taaattgtcc
    35281 aaggcacctc ggatcacttt ttcctgatca gcatgatttt ctttatgcat caaattcgca
    35341 caatctaaaa tgatttttaa atttggtgaa gctacttcat cgattaaacg tttagctaac
    35401 tgatagttat agattggatg attgatccct gcttcaacag caacagttac gccaaaattt
    35461 tctgcatgag cgactaattc aatgatagaa tttctggcga tctgataagc ttcttcagta
    35521 aaattttctt ttgtgtaacc gacagagaca ctaccggttt ccgtagcaat catcttggct
    35581 tgataggcag agcacagagc aatttgctgt ttgaaagttg ccaatgcttg tgcacgaact
    35641 tcttgatttt tgctggatag gttgatatag catcctaaaa tggaaagttc gatattgttt
    35701 ttttggaagt attcaccaaa ataggcagca ctcccaagtg tcatgtcagt taatttaagt
    35761 tgttcaggaa atgctttttg tggtgcaaat tggatatggg acaagtgaag ctgtgatact
    35821 ttttgaacga tttcttcacg atttcgaaca tctaaatcgt gggcacggat gcctaaattt
    35881 aatggaaaca tctcaaactc ctttttgtaa ataattagca agaggcagac gggattcttt
    35941 tatcaattca acaattattc gggcaacttt atcagcgcct tctggactaa agtgggtatt
    36001 gtcttttagt ccttctgggt aatttttaca agtatcaggt ataagatgca ggtagaattt
    36061 ttttgtctct tcttttgaga aggtctggaa caattcttgt gatcttgaga acacatctaa
    36121 aagaggaata tggtgtttct cagcaaatgc acgcatcgct tttggatagt ctccaagtat
    36181 atctggattc aatgttccgt tttctaagta atctcgtcgc gtcacagatg tcagtaagac
    36241 catttggacg ttcgcttttt ttgcgcattc aaaaaatatc tgcagatttt ttaaatagct
    36301 accgaaggga agcgtacctc tttcttcttg gattttctgg tcgttatgtc caaattgtac
    36361 aaataagaaa tcattcggct gaaactgtga agctagacgg gctaaccttc cttcctggat
    36421 aaatgatttg gtgctgcgtc cattctttgc ttggttattg atctggatct cgggtgaaaa
    36481 ataagcagag attttttctc cccaacctgt ctcgggacgc ttgttttcat ctttttctgc
    36541 cgcagtagaa tcaccggcaa tatggatagt aggcatgtta tctcttcttt cataaaggtt
    36601 tataggcaat gaagcagaac agcaagagaa gaagacggag caaatttggt ccgtcttctt
    36661 ctctaaaacg tggataaacg gattccgtta tttcactatc ctgtttttga ttcgttactg
    36721 ttactattaa tcaattaggc aaaaaagcca aagtaatttt tagcatttgt ataactaatc
    36781 gcttgaacta gacttcctaa aagttgttca tcttcaggtg cttctcctcg catgaccatt
    36841 tcgcctaaaa attcacaaag aacacgacgg aaatattcat gtctagtgta ggacaggaaa
    36901 cttcttgaat ctgtcagcat gccgacaaaa ttccccaaag cactaccatc agcaaattgt
    36961 gtcaattgat cgcgcatacc agctcgagta tcgttgtacc accatccaga acctaactgc
    37021 agttttccat tctgttcttt ttggaaacag cccatcaaag ctaaaatcgc aggatagtca
    37081 ttcggattca atgaataaag gatcgtcttt ggcaactgat ccgtttcttc tgcacggttc
    37141 aataattttt gcagaggaat agtcaaagaa agatcattca ttccatcata gccggtatcg
    37201 ggccctaatt tttccaacat ttgtgtatta cagttacgat aagcatggat gtgcagctgc
    37261 atcgtccaat tatgagaatg atagaagtgg gtcaaatgta tcagtgtttc tgtacgataa
    37321 gcatcgattt catctgaaga taatagtttg ttagctcgtg ctttttgaaa aatctcttct
    37381 aatactgttt catccgcttc tttatagcgt aagatgtcta aagcgtggtc ggaaacacga
    37441 catccatgtt gatggaagta ttctatccgc tgccctaaga cttctatcag ttcttgatag
    37501 gtggtgatcg tttggtcagc tgcttcttcc agtagtgtga cccatgcatt aaatccttct
    37561 ttttcaatat tgagtgcttt atctggacgg aatgaaggta gaaccttcaa atctggttct
    37621 tcatgagcaa gcaactgatg atagtgcaag tcgtctgcgg gatcatctgt tgtacaaatc
    37681 acttctacat tcgatttttt tgcgatttcc cgacggcgaa aatcaggagc tgccaaaatt
    37741 tcatttgctt gtgtccaaat tttctctgca ttttcttcat ttatcaacaa gtcaataccg
    37801 aagaaacgct tcaattcaag atgtgaccaa ctgtaaagcg gatttccgat aatttttggt
    37861 acggtttgac accaagctaa aaatttttca aaatcagaag catttcctgt gattttttct
    37921 tcaggcacgc cgcaagctcg catcaagcgc catttgtaat gatcgcctcc taaccaagct
    37981 tctgtcagat tgctgaaatt gttgttttcg taaatttctt ttggatctaa gtgacagtga
    38041 taatcaataa tgggcatgtt ttttgcgtag gaatggtaaa gctttttcgc ccaatcgtct
    38101 tttaataaaa aatcatcaga taaaaacata aatcttcctt ctttcttttt atactgtttt
    38161 atgaaaatca aagtgttact ccgtttttaa aaatggcaat ttctcgaacg tcattttgtt
    38221 catttttcgt ttcttctcca ctagctacag cgatgatttt ttgaacaaac gattctaaga
    38281 ttacttccat tggttgttct aataagacgc ctgcattaaa atccatccaa tgacctttgc
    38341 gttcaaaaag agttgtattc gtagatacct tgaccgttgg gacatatgag ccaaacggag
    38401 tccctcttcc tgtggtaaac aagaccaact ggcaatcgga tgaagcaaga gcagaggcag
    38461 ctacaagatc attcccggga gcttgcaata aactaagccc tggttttctg attttttcgc
    38521 catattgtag cacatcaacg acaggagagc ttcctgattt ttgcgtgcag cctaaagact
    38581 tatcttctaa tgtagtgatc ccacctgctt tattaccagg agatgggttt tcgtaaactg
    38641 gttccccgta agacaagaaa tactgtttga agtcattgat caagtcaacg attgagtcaa
    38701 aaacttcttc attttccgct cgtgccatca atacttgttc tgcgccaaac atttctggca
    38761 cttctgttaa gatcgtgctg cctccttgag caatcaagta gtcagaaaat gcaccaagta
    38821 aaggattagc agttattccc gatagaccat cagaaccgcc gcatttcaaa ccgacattca
    38881 acttagagag cgggactgat atgcgctggt cattttccgc cgctgttaaa agctcttcta
    38941 atagagccac accttgttcg atctcatcgt aaacatcttg agccactaga aatttcactc
    39001 gttcttcatc atattcacct aaaatttttt tgaattcagg aactgtattg ttctcacaac
    39061 ctaatccaaa tactaaaact cctccggcat tgggatgatt tactgcgtcc gctaaaattt
    39121 ctcgagtatt ttgatgatct tttccaagct gcgaacagcc ataaggatgc tttaaaatcg
    39181 taatatggtc aaactgtccc agatctggat gtttttcctt gaactgtttg acgatcagtt
    39241 cagcaatgcc attcacacac ccaacggtag gtactaaaaa caaatcatta cgaatcccta
    39301 cttttccatt ttttcgcaag taaccttgaa atgttcggtt ctcaaaaagg taatgacttg
    39361 gatggacatc tttttcatat cgataatcca attcaccaga aagattggtt tttacattat
    39421 gagtgtgcag ccattgaccg gcagttacgt ctgtcgtcac atgaccgatt ggatagccat
    39481 atttgatcac gttgtctcca gctttcaaat cacccaatgc aatcttatga ccttgcggga
    39541 tatcttcaag agtggtgatc gtttgctgat caatcgtcag ttgtgtttgt tttggaatag
    39601 gggttaatgc gacgaccaca ctgtctcgtc gatttaattt cattgttggt tgcagggttt
    39661 caagcatgga ccatcgttcc tttcatttct tgtaatactg accggacacc tttttgatcg
    39721 atctttgcag ctatttcttg aactgtatct gtcacattcg gtatttgaga caaatcttct
    39781 ccccaaagcg cagcgttttg caataatcga ggaatagctg ttccattatc agaccaagca
    39841 tcagtaaatt cgcttatcgt cttttcatca tcatgtggct ttacttgatc gcctcgatac
    39901 ataagaagta gcgcagctag tgaaacagtg attaacggtg gtacctgatt ttgttcttcg
    39961 atatacttct tgaacactgg aagcagacgg gtgctgaact ttgaaacact atttaatgaa
    40021 atcgcttcta atttgtgatg ggcaaaagga ttcaagaaac gttctttgat ttggtcagca
    40081 taaatggcta attcatcttt aggtaaagaa agcataggaa tcaattctag attgaataac
    40141 tgatcaacat atgcggagaa taaaggatct ttcattactt cttctacagt ttccaattcc
    40201 gccaacaaag caagagggac catcgctgta tgcggtccat taagcaaatg caccttacgt
    40261 tcacgataag gagtcatatc atctgtgatg atgacattca agccagcctg tttgaatggt
    40321 agttgattct ccaattcttt aggcccttcg atcacccaaa gcatgaatgg ttctgctttg
    40381 accatcaatt gatcttcata gttatgccgt tgattgaaaa cacctgcatc ttcgcgagga
    40441 taacctggga cgatgcgatc aactaaacta caacagaaaa cattttcttt ttctaaccac
    40501 tcaacaaaag caggttctaa atcccatttt tctgcgtagc gtaaaatgat ttcttttaga
    40561 cgttcgccgt ttctgtcaat cagttcgcaa ggaatgatgg taaagccagc tttgtttaat
    40621 ttgaaacgtc ggtataaaaa ggctgtcagt ttgcccggga agctctgtgg gggagtatct
    40681 gttaaattat cagtctccac gaattggatt cctgcctctg ttgtattgga gacgatatag
    40741 gccaagtcgt cattttctgc tagagataga taagcatccc attcatcata aggattgatc
    40801 atttgttcta ctacggtgat aatctcggaa gtatcaacga tttcgccatt gctgagtcct
    40861 tgtaaaatga ccgtatataa attatcttgc tggttcatca tatttccaag accttgttct
    40921 aaaggttgaa tgattgcaac attaccttta aacaattgtt ggttattcag ctgctgaatc
    40981 tgccaatcaa taaatccacg cataaaattg ccttcaccaa actgaagaac ttttacaggt
    41041 gcttcgtttt ttttcactaa ttcttttgtc agttttttca tataaacttc ctttctgtgt
    41101 tatgcacacg ttaacatttt tatataaaat tacttgtagt ttacaagtaa ttgatcgact
    41161 cacgaaggat caacaaggtg gagagctcaa ttttagattg ttcgatcgtc ctgccttcga
    41221 tcaaatctag taaaagcttt gttccttctt gacacatttc tttcaaaggc ttacgtacgg
    41281 tggtaagcgg cggattgaga taggagacga ctggagaatc atcgaacccg atcagagaaa
    41341 tgttctgggg aacacggagg ccagctaaat gtacagctct caatgcacca atcgctatgt
    41401 cgtcgttgcc gcaaaaaacc agagtaggca ggtcagaaag tgataatagg tattccatgt
    41461 tttggaggcc gctttctaag ctgtaatctc ctgttaaaaa ataggctgga ttgacaggga
    41521 tgctcgcttt ttttagactt ttcaataccc ctttttcccg ttcttttgtc gaacgaaaat
    41581 ttttctttcc gccaatataa gcgatcttcg tatgtccgca tccaataccg taatctactg
    41641 cctgcataac accggccgca tcatcggcag tgacgttgat aaccgctgga tcattgatgt
    41701 gacgattgac aacaacgaaa ggaaattctt tttctttgag atagtcgatg aaaggctgat
    41761 catcatcact ttgactcata acgatcagtc catcgtagcg ttgcaggttg atttctgtta
    41821 aatcaacaac atcgatactt tcaacagata aactgtaatt tgtgtctaat actgaatgga
    41881 tgcctgcaat ggaatctgct aggaaatttg atgaagttcc tttatgcaaa cttgagaaaa
    41941 atagtccgat tagatatttt ttttgattca ctaaaccttt tgcactatag tttggcgaat
    42001 aattcatttc cttagctagt tgtcgtattt tttgttttgt ttcatttttt attaaactgc
    42061 tgttattcaa agcacgagaa actgtcgtat gagaaacgcc agctgcttta gcgatatctt
    42121 tgatcgttac cattccatca ttttccttac tttttcactt tttgttaacg cattcatcat
    42181 attacgataa ctacgataag tcaatagatc tttgatatga aaagattgca cacgttaaaa
    42241 attacttgga tttttatttt taattatgct attcttgaaa gcggggaatg ctcatttaat
    42301 tagatgagta tcaattttac agaaaaatga aagcctttta ttttaaaagg aggagaggaa
    42361 gaaaatgaag aaaagtacag tattttataa aatattttta ccgatgtttt tattaggagc
    42421 cgtacttgtc ataggattta gtttattcat ttaccagaat acctatgaat cgatcgaatc
    42481 gagttattta acagacaaaa agaatttgct caggcaagtt aaaactaacg ttgaatggaa
    42541 aattagaacg attgaatatt cgttttctac gtatggttcg accaaaaatt tctcggacat
    42601 attcaagcat ccgctgacat atacagatta ctccacttat tctgaaatca ggaaagaact
    42661 aaattttata gaaacgattg ttatggatga taataattat gatttagtca gtttggctgg
    42721 taaatgggga gtaatcaatg gatcgttgag tcaactgacc gaagaggaag ttgaaaagta
    42781 tcaacagaag tacataaata acaaaaataa tttattttgg caaaagaaaa acaaaggaat
    42841 cgaaatggtg atttctttgc caatgtttga aaaagaaaaa tatgcattgg gaattgctac
    42901 gatagagaaa catacaatag aacaagttgt tggtgaaagt ggagaagaca tactttctat
    42961 tgaaaacgaa gttggcaacc tttttactac tcagacagta aaaaataaag agcaaccaac
    43021 tgtattaacg gacgtggatc tagattacaa tcagctgaaa gtgataagag aaaaagataa
    43081 aacgtatata gtactgaaat cagattataa taattggatt tacagattag aagttgactc
    43141 tagtgcaatt ggcgcaatga tccgcaatct gagaatcggg ctagttgcag tgtctttaac
    43201 actggtagga ctcattggtc ttctttccta cttattttcg gacagatttg cccgtccgat
    43261 ttctcaaata caggaacgtc tgaatcttaa atcaaaagga ttcagtggga aagaactaga
    43321 tttggtcgct caatcagtca gtcggatcat aggagaaaaa gaagcgttaa gtgcacactt
    43381 agttacccaa aagccacagc tggaaacgct atttgtactt agtttattta gaaatcgagt
    43441 agaaaggcga gaactagatc agcggttgca gcaatttggt tatagttctc aaaatgactg
    43501 ctattataca gctttggttc aaatcgatct gttagaagat agtcacggtg gggagcgtga
    43561 tttgctactt ttagcgatca acaacatgat cacggaaatt gtgccaaagg aaaatcgaat
    43621 gctgccgatc gttttgaatg aagaaatgca agccactatt tatcgaatgg ataaagatga
    43681 tgcagaagca agcaaaaaag tcatggagta ttgccgactc attcaaaaac gtgtaaaaga
    43741 atacttgaat ttaactatca gtataggcat cagtaaccgg ttcgaaacgc tgaatgaaag
    43801 caagcaatcg gttgatcggg caaaagaagc cctgtattat cgtgtaaata ctggtccaag
    43861 ttcaattatt ttttatcagg aaatcgttcc tgctgctcat gaaaaaacac ttattagata
    43921 tccgatagaa gaacaaaatc gattgtttga agccattcgt tctggaaatc aggaagtgaa
    43981 gaatttagta catgaattga ttgatgcatt gtttgcacaa aataaaaatc ctttgagtcg
    44041 ggaagtagtt tcggtccgct tgatcaatga actcgttcaa ttaggacagt tattgggagt
    44101 agattcaaaa aactttgata acatgaaaca aatttatgta aaagcactga acaattatca
    44161 tcccaaagaa ctagaaaaac ttgttttaga acaattagtt ctgccaatca cagaatgctc
    44221 tcaagcaatc actgatcatg aatttaaaaa tttgtcggag aatattatgc atatcgtcta
    44281 cacagaatat gatcgtgatc tgtctttaga tgtgatcgct gataggttgc attataaccc
    44341 taactattta agtaatgtat ttaaaaagga aacaggagaa aaatttggtg attttgttca
    44401 aaatcatcgt ttagaggtag caaaaaaatg gttgaaagag actaacctct ccgtaaaaga
    44461 gattgcagaa agattgcaat atcgaaatcc gcaaaatttt attcgtttct ttaaaaagaa
    44521 ggaatcgatt acgccgggag aatatcgaaa aaaatatttg tgaatcaaga ggctgttttt
    44581 cttgtggact gattcaagca ataaaagaag ttagaataac cctagtattt gtatttatgg
    44641 atagttaaat ttcaaggcta agcacgcaaa aagaactgtg acaaaagtct tgtcacagtt
    44701 cttttttacg aataaatggc gttcaagaga caggctatcg acaataaggc ataattttgt
    44761 gaaatatggg aagctatttt tcaaaatcgc ttcttattgc tcctgtgggt tactcgtcgc
    44821 aatgtttgtg agagttttta tcatcgctca aggctgaacg tctctttcac aacctctgat
    44881 acacggtgtt ccaggagtag attcttcgaa aaataagccg aaatttcaca aaaatttaag
    44941 aagcaatttt cgtaaatgcc ttcttatttc ttgaagctga ccacttctga cacaactacc
    45001 attttgcgtt cagtacataa tcaccctttg acagaaccta cgagtgctcc tttgacaaaa
    45061 tatttctgaa caaaaggata aacaatcagc ataggcactg ttgcaataac gataacagcc
    45121 attttaactg tttgtgctgg tggaatcaca tcaacggcac tactttctgc ttgcatccca
    45181 cttgatacaa tgacgatttg gcgtaaaaga atctgtatcg gccatttaga tgaatcgttg
    45241 atatacaaaa tagcagtcat ataagtgttc cagtaagtaa cagcataaaa aagcgagata
    45301 gtagcaatag acggtaacgc taatggcagc ataattttga aaaatacacc aaaatctgtg
    45361 caaccatcca tttttgctga ttcttccaaa ctatccggca aggcttggaa aaagtttctc
    45421 ataatgatca tattcattgc attaacagcc acaggcagga tcatggccca gtaagaattg
    45481 accagcccta gagaacgaac aactaagaac gttggaatca tccccccgct gaacaacata
    45541 gaaaatacaa caagaaagtt gacgaaacct cgaccaaaca aatactttct ggaaagaccg
    45601 taggccatca gtgaagttgc acacatactg acgatcgttc cgacacctgt aacaccaatc
    45661 gaaacagcaa gtgctctaaa aatggtcggc gtagaaagaa tgtagcgata cgcgtctaaa
    45721 gaaaaggtag taggaaaaag gataaacttt ttcgcgacga cttcttgtgt agaagcaaaa
    45781 gatgtagcga tgatatttaa aaaaggaacg atacagatca aagctagcaa aattagaaac
    45841 gtattgttga aaagtgtaaa acttctttct cctatagaga ctttcttttt catatagata
    45901 ggctcctcct caaaataaat taaatgtttc tgtttctata tgttcaattt atcatcggtg
    45961 aaagattacg tatataatca tttcctatgc taagtgtcag atagaaaaaa atagaaggtt
    46021 tgctatgcgt agtttatttg tgaaaaaata cactttatcg ttttgtatag cacaaaaatc
    46081 attgctatgt aagcgttttt acttacggta aaaatgatta tatacgtaat tcagatagtt
    46141 atctatcatg aagtcataag cagcaaacat tcacaaaact aaggaggggc ttatggaaag
    46201 tgtaaagaaa caagaaccat ttcaactgac gctatcgaaa aaagaagaaa agctcagaag
    46261 acgaaaaaaa ataattgcag gaatcaaaac gaataaattt ttatatgtga tgattctgcc
    46321 gggagtcctt tatttcttga tttttaggta tcttcctatg gggggactcg ttattgcttt
    46381 tcaagattat caaccatttt taggaataat gggaagtcct tgggtcggtt tcaaacattt
    46441 cattcgtttg tttacagaac cgacattctt tacattatta agaaatacgt tgatcttgtt
    46501 cggattaaat atcttcgtgt tttttccgat gccaatcatt ttgtctttac tattaaatga
    46561 agtaacgaac aaacgattga aaaacgggat tcaaacgatc atttacatcc ctcacttcat
    46621 gtcttgggta atcattgttt cgattactta tgtatttttg aatgttgacg gaggggtatt
    46681 gaatgaattc cttgcaacaa tgggatttga aaaaatcagt tttctaacat cccctgaatg
    46741 gacacgcaca gtatatatcg gacaagtgat ctggaaagag ttgggctggt ctacgatcat
    46801 ctacctttca gcgataactg cagtcgatac acagttgtat gaagctgcag aaatggatgg
    46861 agcaggacgc ttacgcaaaa catggcatgt tacattgccg gcaattcgtc cagtaatcat
    46921 taccttgctg attctaaaaa tcggtcagac attagactta gggttcgagc atatgtactt
    46981 gttattgaat tcattgaatc gaagcgttgc agaaattttc gacacctata tttatacagc
    47041 tggattgaag aatggacagt taagtttcag tacagcaatg ggattgttta aaggggtcgt
    47101 aggattgttt atggtaattt tagctaataa gattgccaaa aagctaggag aagacggcgt
    47161 ttactaagat agaaagagag ggaaagatat gctgcagtca ttagataaaa taaacggaag
    47221 gctaaatcgt attttacagt tggtttattt gaattttctg tggggcggtt tagtcatcgc
    47281 aggtttggga gtttttactt tcggtcctgc atcgtatgcg atggttgcag tgattagaaa
    47341 atggctgcgc tcaaaagaaa cgtttccttt gacgaaaacg tacttcacat attttaaaga
    47401 aaactatcgt gaaaccttgc tgatgagctg gatatatggc gccatcggga ttgttttact
    47461 tgtggatctt tctttcatac acaattggta tcttaggatc gctttgtata ttgctgcgtt
    47521 catatatgtg ctctcagcac tctatatttt cccaatcatg gctcattatg attggaaagg
    47581 atattttttc aaaatgaaaa tggcattttt attcggattc tcacatcttc attactcatt
    47641 agtgttgata ttaagtatgg tagggattta tctgatgatc atccaaacaa tgccaggtgt
    47701 tttaaccttt atcggtggca gtctcttctt ttccgcagtc acgtggacag caaattctat
    47761 attttgccat ttggaatgga agaactcata tacagaaaaa acagaagaaa acaaaaatat
    47821 tattaaaaca gtgaaggaga aaatttatga aaaaagcaac gctcgtaaaa ttaggtctta
    47881 gttttgcagg aattctagca cttgccgcat gcggcagcag ttcaagtaac agttcttcag
    47941 agacagaaga tggaaaagct aaaatcactt ggttaaatat tttgcatcat gcttcaccgc
    48001 ctacagacac gattgtgaac ttgatcgaag aaaaaaccga tacggaactg acattcaact
    48061 ggattcctga tgcttcaaaa gaagaaagat taacaactgc attggcttct gatgaactag
    48121 gagatatcgt tacacttcaa attgcgatgt tgaaaaactc ttctgtccgc aatgcgttaa
    48181 aatcaggcgt attctgggat gtatcagaat atttaaaaga ctataaaaat ttaagtcaaa
    48241 tttctgaaga tagaatcgaa gctgcgagta tcgacggtgc cttgtacggc gtaccgatac
    48301 aaaaagacta cgctcgtgct ggcttagtca ttcgaaaaga ctggttggat aatctaggac
    48361 tagatgttcc aactaccatg gatgagcttt atgaagtagc taaacaattt acagaaaacg
    48421 atcctgatgg aaatggtgtg gacgacacag ttggttttgg cgatcgtgcg cctagtgata
    48481 ttcgttatac cagctttaaa cttttcactt cttattttgg agcaccaaat ggctgggctg
    48541 tagacgataa tggcaaattc actccagaat ttgatacaga agagtatatg aaagctttga
    48601 atttttcaag agatctattt gagaatggct atttggcaca agactttgca gttacccaaa
    48661 agactgatca gcaagaacaa tttgcacaag gaagaactgg aatctacact ggaatggtgg
    48721 atatcaagaa tctgaagacg atgggtcaag gtattcaaga tgatatggaa ttagtgcctg
    48781 taaacaagat ctcagatggt gaaggcggcg gttatcatgt ttggtcagaa ggaaatggta
    48841 ttggcggctt gctagcattt cccaaatctc aagtaaaaga cgaagcacaa ttgaagaaat
    48901 tacttcaatt tgttgatgat cttttagaag aagatgtgta taaattgatg actggcggta
    48961 tcgaaggaac gcattatgaa ttgaatgatg atggttctat cgaatttatc gatatggatc
    49021 tttggcaaca agaggtgcaa ccgttatcaa gctctcgtcc tagtgaagtg acgttctctt
    49081 tcaaagatac agaccctgaa aaagaattct ctaatcaatt gatcaaagaa aatgaagaat
    49141 ttgctgtaat ggatccttct gtgccattgg attcaccgac gaacaatgaa gtaggatcag
    49201 aaattgaaaa aatcgtcatt gatgctacgg tgcaatacat catgggacag cttgacgaag
    49261 atggattcaa aaaagctgta gaagactgga aagcacaagg aggcgatcga atcacacaag
    49321 agtacgagga agcatacaaa gcagcggcac agtaatatag acgattggga caaatacttc
    49381 ttggtatttg tcccaaatcc tattttaatt tttaaaggag agcaaataat ggaaaactgg
    49441 tcaaagaaat tagcaaaaag tatcatggaa agaacacctc gcttatatga agaaaagtgg
    49501 tataaaggaa aatggtctta tgactatggc gtcgtactta aagggttcca attactttgg
    49561 gaacgaaccc aagaaaaaat ttattttgat ttcataaaag acaatatcga ctatttcgtg
    49621 caagaagatg gaacgatccg tggctacagc gttgaagaat acaatatcga ccatgtaaat
    49681 acaggaaagc ttttcttttt attgtacaaa gaaacaggcg aagaaaaata taaaaaagca
    49741 gcagaactcc tttcccagca gttggcaaac catccacgca catccgaagg agctttttgg
    49801 cataaagaaa tttatcctta tcaaatttgg ttggatggct tatatatggg ttctcctttt
    49861 tatgctgaat ttatccagaa ttttagtgaa gaaaaagatt accaagatgt tttgagacag
    49921 tttgaaatca gttataaaca tctattcgat ccaaaaacaa atttgctgat tcatgcatgg
    49981 gatgaaaaga aggtccaacc atgggctgat ccaaaaacag gtctatccca tcatttttgg
    50041 agccgatcga ttggctggta tttgatggct gcagcagata cctatgaatt acttcatgaa
    50101 gaaacagatt gttctttgct gaaagaaatt ctagaaaaga cactggctgc attacttcca
    50161 tatcaagaag aaaacagcgg gacatggtat caagtaacaa cagaaacaaa acggaaagga
    50221 aattatctgg aagcttccgg cagtagtatg tttgtttacg caatggctaa aggaatacgt
    50281 ttgggactgc tgaacaaaga agaatggctt ccacaagtga agaaatcaca tcaaggatta
    50341 cttgatgaat ttgttctgga aacaaaagaa ggctggctga acttgaataa aaactgtcaa
    50401 gtagcagggt taggcggagc agatcagcga gatggttcat atgcttacta catcagtgaa
    50461 ccaattattt gtaatgatca aaaaggcgtt ggtgcattct tgcaagcatt gattgaagtg
    50521 gaggcattat aaatatgtat gatattttga catttggcgc atcaattgat gaattgaata
    50581 ctgaagcaat acaacaagcc attgatgctg cagcaagtga cggaggcggg accgtagttg
    50641 ttccagcagg tgaatttcta acaggagctt tatttttaaa aagcaatgtc gaacttcatt
    50701 taagcgcagg agcggttctg aaattctctg acgatccaaa agattatcct gttgttcatt
    50761 cacgttggga aggagtccat cgaaaagttt atgcttcctg tatctatgct caaaatgtag
    50821 agaacatctc tgtcactggt ttcggtacat tagatggaaa tggaaaaaaa tggtggcata
    50881 cttttagaaa tgaaccagat aatctcgctt atcctcgtcc taaattgatg agtttccata
    50941 actgtcatcg aattactgtg aaagatatta aattgatcca gtcaccaagt tggacgatca
    51001 acccgattct ttgcagtaat gcaacgtttg ataacttgac gatcttgaac ccagcggatt
    51061 caccaaatac agacggaatt gatccagaat catgcaaaaa tgtgcgtatt agtaattgcc
    51121 atattgacgt gggagatgac tgtattgcaa tcaaggcagg gactgaagat acgtacgaaa
    51181 ggatcgcttg cgaaaatatc acgatcacaa attgcacgat ggtccatgga catggcggtg
    51241 tcgtattagg aagtgaaatg agtggtagta ttcgtaatat taccatttca aattgtatct
    51301 tccaagaaac tgatcgagga atacgattga aatctagacg aggtcgaggc gggatcgttg
    51361 aagatattcg agtatccaat atagtcatgg ataatgtgat gtgtccattt atactgaatc
    51421 tttattattt ctgtggtccg cgagggaaag aaccgtatgt atgggaaaaa aaggcttatc
    51481 cgatagatga acggacacca gcattcagaa ggatccattt ttcgaatatc acggcaagga
    51541 atgtccatgc ttctgcaggt tttatttatg gattagcgga acaattcata caagaaatca
    51601 catttgacaa tatcgatgtc tcgatggccc aagatgcagt tcccggtgtt cctgctatga
    51661 tgacaggaat agaggaaatg agcagacaag gattttatat tggctttgcg ggtaaggttt
    51721 cctttaacca gatgtcgatt gaaaatcacg agggaccagc atttctatta gaaaatacta
    51781 aagaaatcag tattgagaaa ttccaatcaa atcaatcaga aaatatggat gaactggttg
    51841 ttcgtaaaaa ctttgcttat gcagttgaat gattttttag gtgctccatc tagcagacat
    51901 acccctagtg gaaaacgatt ataccgagaa aaacaaaacg gttttatgct tgaatactat
    51961 caattgtact taaatgaatt ggaaacagta ccagccctct atgcttatcc agaaaaagaa
    52021 ggaccgtttc cgccggtcct ttacctgcat tctcacggcg gagatttttc agtcgggaaa
    52081 agtgaattga tccatggtgc tccttactta gcttctccat cttttgcaga agtactgaca
    52141 ggaatgggat atgctgtttg gtcgattgat gcttggggat ttgaagaacg cggaggtatt
    52201 tctgaaagcg agttgttcaa acaattttta ttaacaggaa aaacgttatg gggaatgcgt
    52261 atttatgatg tgatcagctt gatcgattat ttggagacaa gggaagacac agatactcaa
    52321 cggctcgcaa cgattggtct ttctatggga ggcttattaa gctggtgggt gacagcattg
    52381 gattctcgtg tcaaagtttg tattgatcta gcggcacagg tggacatcga aatacttttg
    52441 ctacatcgcc gcctagatca tcatgggttt tattactatg tgccaaatct attgacagct
    52501 tatacaacgt tagcaatcca agaaaaaatc gctccgcgcc ctcgtcttag cttagttgga
    52561 aaaaacgata cgatgtgctt ggacgaaggc gtactgaagc tgagaaaagg gctggacaaa
    52621 aagtatcaat caatgggtag tccagaaaac ttttcttctt tttctttaac aggcggtcat
    52681 atggaaacac aagaaatgag aaatatttgg aaacaattca taagggagca tttatgagga
    52741 tgaaagacaa actgataatt ggaaagaatg ctatagatac cccgacggat tttgaaacta
    52801 tccaagaagg aatcgattat ttggcaggcc tgccggatag ccatccaaag gtcttgatag
    52861 taaaagaagg aagatatgat gaatatatag aaagcagatt atccaatttt aaacttgtgg
    52921 gagcaggaac agtagttatc tccggtaatc gttttgcaaa acaggagtat cttgacggta
    52981 gccagttagg gactttccga agtgctactt ttttcttaga aggatcgaat gtcgtattag
    53041 aaaatcttca catcgaaaat acagcaggtc caggagaaaa ggtaggacag gctgttgctt
    53101 tattcaattc aggagatcgc gtatctttaa aaaactgtcg actatctggt tatcaggata
    53161 ccttatgcac gggtccgttg cctgatttgc aaaaagatgg tactcctttt tgtacaccgg
    53221 cttctgccaa tcctgagtat tgtcgtcaga cctatgaata ttgctggatt gaaggaacgg
    53281 tggatttcat atttggtggg gcagatgccg tttttcatca gtgtcatatc catagcttag
    53341 ccagtaaaaa tcctggatac atcacagcag catctacgcc gaaaaatcaa aaaacagggt
    53401 atcgttttga aagctgtacc ttgactgcag aacctgatac tagaaacgtc tatttaggaa
    53461 gaccgtggcg tccgtatgca aatgtcttat ttgaagcgtg taagataggt gggcatgttc
    53521 acccaactgg ttgggataat tgggatgaca agaaaaatga acagactgtc aaattctctg
    53581 aacgtaataa caattatgaa acatcgatca aaagacctga atggatacat ttagaaaagc
    53641 agggggttca gaaatgaaaa gaaaatggga actattgcta ggaatggtcg gtggcagtct
    53701 atctttgatt ttctttggcg ggttagcagt tactttaagt aatatgtctg cgtcagagtt
    53761 taaaaaaagt tatcagtcgc ttgctgtaga tcattcaact ttgtctttag aaaatacatt
    53821 tggattatta caggacatga ctggtctgtt tgccgttgtg ttgtttattt cacttgcttt
    53881 tttagcagta gcattgtttt tgactgctaa aggaaaatac ttaacaactg ccactggttt
    53941 gtattttata acaggattca tattgttgat tggcactcag tttattgcgt ttccttttgc
    54001 atttttttat ttcgcagctg gggcattcag tttatatcga gtaagaatga gaaaaggagc
    54061 ctgaatcatg cagactatca aagtgaaaaa tcctatttta agaggattca atccagatcc
    54121 taatatatta agagtgaaag agcggtatta cattattgtc tcctcttttg aatggcttcc
    54181 aggaatccga gtatatgagt cgaaaaattt agtcaactgg tcacatacaa cggatatttt
    54241 gaccactcaa gtatctttgc aaggaaatcc tacaaatgga agtatatggg cgccacaaat
    54301 cagttatgct gatggattgt tttatcttgt ttacacagat gtcaaaagtg caggccgtcc
    54361 gtttaaagat gtccacaatt atttgatcac tgcatctgag atcacaggtc cttggtccga
    54421 accaatttat ttaaatagta acggctttga tccttctttg ttccatgatc ttgaaacggg
    54481 aaaaaaatgg cttgtcaatg aactatggga ttatcgtctg gacacaccga ataaatccag
    54541 cggtatcgta ttacaagaat atgatgcaga gaagaagaag cttgatggtc ccatctataa
    54601 aatatttgca ggtacagaat tagcgaaaac ggaggcacca catttgtatt ttcgtaacgg
    54661 gtattattat ttgatgacgg cagaaggcgg tacaggaaga ggacattcag ttacagtttg
    54721 ccgagcaaag aatattactg gtccttacga gcttgatcct ggttttccta tgctgacagc
    54781 tagtgacaaa cctgcttcta cattgcaatg tacaggacat gggagcttag tacaaacccc
    54841 gtcaggaaga tggtacatga catatctttg taccagacca ttaaacggtg cggctatttt
    54901 gggaagagaa accgctattc aagaagtgta ttggacgtcc gacgattggt taagacttaa
    54961 agatagccag acaactccga tggaagaaat aatgattgag acaaatgaag aggtacaaca
    55021 agaaaaagat catcagttta tggatacatt tgaaggagag ctaaagaaga actggaatgc
    55081 cagacgcatt ttgccaaatg ctgattggtg tgatacaaaa tgtagaccag gttttttacg
    55141 tctgatttcc ggtgaatctc ttcaatctac cttcgaacat catttgttag ctattcggca
    55201 aacggatttt acttttgatg cggagacagc atttgaatac atgcctaata attttaatca
    55261 gatggctgga ctggtactgt acttaaatga atccaattat atttattgtt atgttacttg
    55321 gaatgaggac aagggaaaat gcctacgtat gatagaatca gaaaacggag tagcacaaat
    55381 agaagattgg acgattccac tcacagaaaa gaagactttt ttgaaagtca ctgtaaagaa
    55441 agagacagca cagtttcatt tgaaagacgt atcaactgaa gaatggaaga aagtaggtcc
    55501 gcaaaaaaac atgtgtatac tctcaggagg gtttactgga aattttatcg ggatagcagt
    55561 gcatgatcta aataaaaaaa gaggaagtta tgctgatttt gagtttttca agtatgatgg
    55621 aaaagatcat ctgtaattta attctttaat aaatgaggtt cactaactta ttttcactag
    55681 ttagtgaatt tttttgtttg tatatattgt tatgtaaaaa aagttatcaa tcttatgcat
    55741 caatgttttt agattatttt ttgtttttta tctgtcaaga taatgcaata aaaagccaac
    55801 attgtgaata taaaaacaag aaaaaaagag ttataatttt gaaaacgttt actagaagag
    55861 gtaggaggaa ttcaaatgct ttcacaaaat gctgttacag caaatacaat aaaaaaagaa
    55921 aaaaaggaat ttgggatttc cgataagata ggctacatgt tcggtgatct aggtaactgt
    55981 tttattttag gtttagtcaa tagtttcttg atgatttatt atacgaatgt tcttggcgtt
    56041 tcaggggcaa tcgtaggtac gttattcttg atttcgagaa ttttggatgc gtttgctgat
    56101 gtgatggttg gaagattatg tgatgtctca gagttaacag aaactggccg atttattcct
    56161 tggatcagaa aaatgaagta tccattttgc ttagtgactg tcattttgtt tttgccattc
    56221 gtccaacatc ttccaatgac ggtgaagatt gcttatattt ttgtttcata cattgtttat
    56281 gggatttttc tctcaacaat caatatcccg tatggagcaa tggcagcagc aattagctca
    56341 aatcctaatg accgcacctc gttgtccacg ttccgaagca ttggttctgc gattggcgga
    56401 tcaactacag gattcttcat tccgatttta atgtataccc ataacaagag tggacaacaa
    56461 gtcgtttcag ggaatcattt cttttggatt tcaatcggat gtgctgcaat agcatttgtc
    56521 gcatatatgt taacttgtaa attgactact gaaagagtaa gagttgtcaa aaacgaaaaa
    56581 gtatctgctt ctcagttggt aaaaggtttg ttagctaatc gagcactgat tattttagtc
    56641 attgttgaca ttttcattgt gatcaatcag attttagctg ggacgaatat gacttattta
    56701 ttcaatgatt acttccataa taaacaagca atgtctgttg ctcttttatt tacttacgga
    56761 acagtagtag ttttagcacc atttgctaca aagctgacaa aattatttgg taaaaaggaa
    56821 gcaagcgtat ttgcgttact tgcttcttca tgtatgtact tgctgatgta tttccttcat
    56881 ataacaaatg catgggtata tctgattctt ttatttatcg ctactttagg atctggttta
    56941 ttcaatttga tggtctgggc attcattact gacgtgattg attatcatca atataagaca
    57001 ggcttaagag aagatggaac agtatatgga gtaaattctt ttgcgagaaa agtaggacaa
    57061 gcatgtgcag gagcggtagg cggatttatg ctggcactca ttggttacca atcgtctaca
    57121 acaggtggag ccatccaatc agttttagta caagaaagga tttatacgat ggcaaacttg
    57181 ttaccagcat tctgcttatt tgtatccgca atcattttgc tagtaggtta cccactgaat
    57241 cgttcaaaaa ctgtatttat tggtgaagaa ttgaaaaaaa tcaatgaaag atagggagaa
    57301 acgtattgcg gacaaaaaaa gggattatca atgctttgaa ctttaaaaca aacgacactc
    57361 aacaagatga tacaataata ctgcaaaaag caatcgatca aggtgcgaaa gaacacttac
    57421 ctgtatttat tccaaaaggc atttatttag tcggagccct ttttttaaaa gataagagtc
    57481 atcttatctt tgaagaaggt gcagtcctca aggggagaac agatatcgaa gcatttccag
    57541 aaatcgatac acgagtagcc ggcgtagaaa tgaaatggcc agcagcgatt ttgaatgttc
    57601 tctcggcgaa agatattctt atagaaggaa aaggaataat cgacggtcaa ggagaccatt
    57661 ggtgggagct gtattgggga aaagatcaaa aaagcgggac aagagctgaa tacgatcaaa
    57721 agggacttcg ttggattgcg gattatgcta ttaaacgtcc acgcgcttgt ttactgtatc
    57781 atgcagaaca tgttgttgtt cgtgatttga tttttcagaa atcaggtttt tggaacttgc
    57841 aaatcactta ttctaacgat gtattagtag aaaaagtaat catccgcaac aatgatggac
    57901 caagtacaga tgggattgat attgattctt caacaaatgt gcgtgtctat gaatgtgatt
    57961 tggcctgtgg tgatgattgt attgctatta agtctggcag agatggcaat ggtgcaagag
    58021 tcaatcgaaa atcatcaaga atcgaggttg ctagatgtaa aatccgttca ggatacggtg
    58081 taactattgg tagcgaagtt agtgctggag ttagtgacgt atatattcac gatatcgatt
    58141 tttttcagtc agactgtggt attcgaatga aatcttcaaa agaaagaggg ggagtgatcg
    58201 aaaatatcag ggtagaaaat ctgaatatga ttgatgtaca atttcctttt tcttggataa
    58261 tggactggca taatgaatac aatagaaaaa atagcaatga ccttgctcaa atgccagaaa
    58321 gttggcaagc agtggctgaa gaaatacctg aatcaaagca aatgacgaaa gtcaaagaca
    58381 tacacatcaa aaacgtacag gcatgccttt ctccaggtta ctcacttcct tcccgagctt
    58441 ttgatttagt agcatttcct gaaaagccta tagaagatgt ctgcttttct cattgccaaa
    58501 taactgcaaa agaattcggg cgaatcgaag cagtacaaaa cttatgtttc aaaagctgtg
    58561 atttatctat agaaactggc aacacagctg caaacaatac ttttgacaat cgttgaaatt
    58621 ataataaggt caagcttaaa taatatttta gcttgacctt tatttttttt aatgatatat
    58681 taaacaacgt tgtcgcgctt cattgaaaca ttttatgaaa attccaaaaa agagttgaca
    58741 catgttttta gacgtgataa gataactaag tcgttaaaaa gaaccacttg cgaagcttga
    58801 ttctatcgaa aaaaacttca aaaaagttct tgacaaataa caaacgataa gttatgataa
    58861 atgagttgct gaaagatttc gaaaaacgaa atcgaaaaaa acttttaaaa aagagttgac
    58921 aatcgtttgt ctctctgata tgatataaaa gttgctacgg cagccaaaaa tgaatcggga
    58981 aacactctcg atgaagtaga cctttgaaaa ctgaacaaag taagacaaac caaatgtgta
    59041 gggcgtcttg attcaattca agacaa
//
LOCUS       DBBGSP010000013        53902 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000013 DBBGSP010000000
VERSION     DBBGSP010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 53902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53902
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.013"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(73..1014)
                     /gene="ribF"
                     /locus_tag="ACIZE9_000932"
     CDS             complement(73..1014)
                     /gene="ribF"
                     /locus_tag="ACIZE9_000932"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HGC6092814.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(1018..1941)
                     /gene="truB"
                     /locus_tag="ACIZE9_000933"
     CDS             complement(1018..1941)
                     /gene="truB"
                     /locus_tag="ACIZE9_000933"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGC6092815.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(2309..4671)
                     /locus_tag="ACIZE9_000934"
                     /pseudo
     CDS             complement(2309..4671)
                     /locus_tag="ACIZE9_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
     gene            4836..5292
                     /locus_tag="ACIZE9_000935"
                     /pseudo
     CDS             4836..5292
                     /locus_tag="ACIZE9_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            complement(5449..5796)
                     /gene="rbfA"
                     /locus_tag="ACIZE9_000936"
     CDS             complement(5449..5796)
                     /gene="rbfA"
                     /locus_tag="ACIZE9_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGC6092816.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(5823..8129)
                     /gene="infB"
                     /locus_tag="ACIZE9_000937"
     CDS             complement(5823..8129)
                     /gene="infB"
                     /locus_tag="ACIZE9_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGC6092817.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(8142..8453)
                     /locus_tag="ACIZE9_000938"
     CDS             complement(8142..8453)
                     /locus_tag="ACIZE9_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGC6092818.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(8450..8743)
                     /locus_tag="ACIZE9_000939"
     CDS             complement(8450..8743)
                     /locus_tag="ACIZE9_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGC6092819.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(8765..9940)
                     /gene="nusA"
                     /locus_tag="ACIZE9_000940"
     CDS             complement(8765..9940)
                     /gene="nusA"
                     /locus_tag="ACIZE9_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGC6092820.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(9963..10436)
                     /gene="rimP"
                     /locus_tag="ACIZE9_000941"
     CDS             complement(9963..10436)
                     /gene="rimP"
                     /locus_tag="ACIZE9_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGC6092821.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(10581..14939)
                     /locus_tag="ACIZE9_000942"
     CDS             complement(10581..14939)
                     /locus_tag="ACIZE9_000942"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGC6092822.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(15151..16860)
                     /locus_tag="ACIZE9_000943"
     CDS             complement(15151..16860)
                     /locus_tag="ACIZE9_000943"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGC6092823.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(16928..18196)
                     /gene="rseP"
                     /locus_tag="ACIZE9_000944"
     CDS             complement(16928..18196)
                     /gene="rseP"
                     /locus_tag="ACIZE9_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGC6092824.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(18357..19157)
                     /locus_tag="ACIZE9_000945"
     CDS             complement(18357..19157)
                     /locus_tag="ACIZE9_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGC6092825.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(19154..19966)
                     /locus_tag="ACIZE9_000946"
     CDS             complement(19154..19966)
                     /locus_tag="ACIZE9_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGC6092826.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(20161..20718)
                     /gene="frr"
                     /locus_tag="ACIZE9_000947"
     CDS             complement(20161..20718)
                     /gene="frr"
                     /locus_tag="ACIZE9_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGC6092827.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(20721..21443)
                     /gene="pyrH"
                     /locus_tag="ACIZE9_000948"
     CDS             complement(20721..21443)
                     /gene="pyrH"
                     /locus_tag="ACIZE9_000948"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGC6092828.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(21579..22460)
                     /gene="tsf"
                     /locus_tag="ACIZE9_000949"
     CDS             complement(21579..22460)
                     /gene="tsf"
                     /locus_tag="ACIZE9_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGC6092829.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(22559..23341)
                     /gene="rpsB"
                     /locus_tag="ACIZE9_000950"
     CDS             complement(22559..23341)
                     /gene="rpsB"
                     /locus_tag="ACIZE9_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGC6092830.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            23700..24179
                     /locus_tag="ACIZE9_000951"
     CDS             23700..24179
                     /locus_tag="ACIZE9_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGC6092831.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            24396..25487
                     /gene="phnW"
                     /locus_tag="ACIZE9_000952"
     CDS             24396..25487
                     /gene="phnW"
                     /locus_tag="ACIZE9_000952"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HGC6092832.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            25480..25608
                     /locus_tag="ACIZE9_000953"
     CDS             25480..25608
                     /locus_tag="ACIZE9_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HGC6092833.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            25612..26157
                     /locus_tag="ACIZE9_000954"
     CDS             25612..26157
                     /locus_tag="ACIZE9_000954"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HGC6092834.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(26611..28302)
                     /gene="argS"
                     /locus_tag="ACIZE9_000955"
     CDS             complement(26611..28302)
                     /gene="argS"
                     /locus_tag="ACIZE9_000955"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGC6092835.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(28722..29669)
                     /gene="arcC"
                     /locus_tag="ACIZE9_000956"
     CDS             complement(28722..29669)
                     /gene="arcC"
                     /locus_tag="ACIZE9_000956"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGC6092836.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(29784..30803)
                     /gene="argF"
                     /locus_tag="ACIZE9_000957"
     CDS             complement(29784..30803)
                     /gene="argF"
                     /locus_tag="ACIZE9_000957"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGC6092837.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(30894..32123)
                     /gene="arcA"
                     /locus_tag="ACIZE9_000958"
     CDS             complement(30894..32123)
                     /gene="arcA"
                     /locus_tag="ACIZE9_000958"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGC6092838.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            32584..33285
                     /locus_tag="ACIZE9_000959"
     CDS             32584..33285
                     /locus_tag="ACIZE9_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGC6092839.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(33894..34910)
                     /gene="tsaD"
                     /locus_tag="ACIZE9_000960"
     CDS             complement(33894..34910)
                     /gene="tsaD"
                     /locus_tag="ACIZE9_000960"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGC6092840.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(34907..35371)
                     /gene="rimI"
                     /locus_tag="ACIZE9_000961"
     CDS             complement(34907..35371)
                     /gene="rimI"
                     /locus_tag="ACIZE9_000961"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGC6092841.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(35378..35920)
                     /gene="rimI"
                     /locus_tag="ACIZE9_000962"
     CDS             complement(35378..35920)
                     /gene="rimI"
                     /locus_tag="ACIZE9_000962"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGC6092842.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(35904..36626)
                     /gene="tsaB"
                     /locus_tag="ACIZE9_000963"
     CDS             complement(35904..36626)
                     /gene="tsaB"
                     /locus_tag="ACIZE9_000963"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGC6092843.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(36817..37797)
                     /locus_tag="ACIZE9_000964"
     CDS             complement(36817..37797)
                     /locus_tag="ACIZE9_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6092844.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(37821..39305)
                     /gene="galT"
                     /locus_tag="ACIZE9_000965"
     CDS             complement(37821..39305)
                     /gene="galT"
                     /locus_tag="ACIZE9_000965"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGC6092845.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(39317..40306)
                     /gene="galE"
                     /locus_tag="ACIZE9_000966"
     CDS             complement(39317..40306)
                     /gene="galE"
                     /locus_tag="ACIZE9_000966"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGC6092846.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            40554..40721
                     /locus_tag="ACIZE9_000967"
     CDS             40554..40721
                     /locus_tag="ACIZE9_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGC6092847.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(40783..42594)
                     /locus_tag="ACIZE9_000968"
     CDS             complement(40783..42594)
                     /locus_tag="ACIZE9_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HGC6092848.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(42591..42956)
                     /locus_tag="ACIZE9_000969"
     CDS             complement(42591..42956)
                     /locus_tag="ACIZE9_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HGC6092849.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(43119..43514)
                     /locus_tag="ACIZE9_000970"
     CDS             complement(43119..43514)
                     /locus_tag="ACIZE9_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGC6092850.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(43532..44494)
                     /locus_tag="ACIZE9_000971"
     CDS             complement(43532..44494)
                     /locus_tag="ACIZE9_000971"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGC6092851.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(44494..44706)
                     /locus_tag="ACIZE9_000972"
     CDS             complement(44494..44706)
                     /locus_tag="ACIZE9_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGC6092852.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(44727..45425)
                     /locus_tag="ACIZE9_000973"
     CDS             complement(44727..45425)
                     /locus_tag="ACIZE9_000973"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGC6092853.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(45445..45987)
                     /locus_tag="ACIZE9_000974"
     CDS             complement(45445..45987)
                     /locus_tag="ACIZE9_000974"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGC6092854.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(46119..47123)
                     /locus_tag="ACIZE9_000975"
     CDS             complement(46119..47123)
                     /locus_tag="ACIZE9_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGC6092855.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(47120..48109)
                     /locus_tag="ACIZE9_000976"
     CDS             complement(47120..48109)
                     /locus_tag="ACIZE9_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGC6092856.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(48106..48912)
                     /locus_tag="ACIZE9_000977"
     CDS             complement(48106..48912)
                     /locus_tag="ACIZE9_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092857.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            49078..50034
                     /locus_tag="ACIZE9_000978"
     CDS             49078..50034
                     /locus_tag="ACIZE9_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6092858.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(50111..50629)
                     /locus_tag="ACIZE9_000979"
     CDS             complement(50111..50629)
                     /locus_tag="ACIZE9_000979"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGC6092859.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(50717..50866)
                     /gene="rpmG"
                     /locus_tag="ACIZE9_000980"
     CDS             complement(50717..50866)
                     /gene="rpmG"
                     /locus_tag="ACIZE9_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGC6092860.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            51094..51540
                     /locus_tag="ACIZE9_000981"
     CDS             51094..51540
                     /locus_tag="ACIZE9_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HGC6092861.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(51735..53630)
                     /gene="asnB"
                     /locus_tag="ACIZE9_000982"
     CDS             complement(51735..53630)
                     /gene="asnB"
                     /locus_tag="ACIZE9_000982"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HGC6092862.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT        15122 a        11496 c         9439 g        17845 t
ORIGIN      
        1 ctgggcttat ttatcaccca ttttattgta attgctagtt atacataaac aagagatttt
       61 atgcataatg ttttattgct gagaaaaata ttcagctgtt gcttgttcat cctccttgag
      121 ttgttcaatc aattcctcta cactagaaaa tttcacttga tctcttaaaa attgattcca
      181 gcgtaccgcg acatgttcac catagatatc ttgattaaag tccaaaatat acaactctac
      241 agtcagctcc cgtccttcac cgaatgtatc attatgtcca attgaaccca tggctggata
      301 ccatgtttcc ccaattttta tttccgacac ataaacacct tctttaggca aatgaaccgt
      361 gctctttact ttgacatttg ctgtagggaa tcctagtagt ctgcctcgtg catcgccatg
      421 gacaactacc ccttctacct catatgtgca acctaatagt tttgctgctt cttttacttg
      481 tccgctgtct agtaatccac gaatacgggt agagctgatt ttttcacctt gttcttcttc
      541 tttagaaact gtgacgattt tgaatcttcc tttggcatat tcaggaaaat gagcgacatc
      601 tgcaatgtct tttggtccat acgtataatc aaaaccggaa acagcatatt ttgcatgtaa
      661 ccctacgatg tattgatcaa caaattcctg cggtgctaaa tgagcaaaag aagaagtaaa
      721 atcaacttca tataaataat ctatacccaa agcggccatt ttttcttctt tttgcttaag
      781 gctagtcaaa tatttcacgc tgctaggatc gatcttttta aagacaatag atggatgctg
      841 attgaaagtc atcaatgcta atttcaatcc ttctttttgt gcaatttcca tacctgtctt
      901 tatgactttc tggtgtccga tatgcacgcc gtcgaaaaat cccagcacta aaacgacatc
      961 gtcttctgga atttgttctg attggtaagg atgtctgatc ttgatgatat tcattcgtta
     1021 ttcctcattt ctcaatactt tactaggttt taatttgttt ttttctttcg ggtttggctg
     1081 ataaatactg acaacttttc ctttataaaa caaagcaatt tcttctgacg gcatttctgg
     1141 gagcgcaaat acagtataat caagtctcat accgtttttt actttctgcc atacttcatc
     1201 agtaatatct actcgtttga accgttccac tcctttttct attggcagca aacaatcatc
     1261 gattgtccca tttttcacag cttgagctac ttcttctaat gtcagagcat ccttctggga
     1321 cataccggca cttgctgttc gggtcagatc agacatgtgc gcagggtaac caagtttctt
     1381 gcctgtatct acagctaatg tgcggacata ggttcctttc ccgcattcta cttcgaagcg
     1441 ccaagaaatg gttcctgtca cttcgtctct tgtcaattca cttgtccgga taaaacggta
     1501 aatctgagcc tttctaacag gacgctccac tgtttcatta ttgcgggcat attcatataa
     1561 ccgcttaccg ttgactttta ccgctgagta cattggtggt atctgggtga tctcaccaat
     1621 aaatgaagcc atcacttcat ctattttttt ttcagataaa gacatatcta ctggttttgt
     1681 ttctacccgt tctccggatc gatcttccgt cgttgtactg aaacctagag ttatctcgcc
     1741 tacatagatt ttcccagaat ctgtcaaata ttcgataact tttgtggctt ttccaataca
     1801 aatgggcaac acaccgtcta cgtctgggtc aagcgtaccc ccatgtccga tttttttcgt
     1861 atgtaagatt tttcttaatt tgaatacgca atcatgactt gtcattccgc gttctttcca
     1921 taaaggtaat aacccgtcca tgtcttttct ccatttcatt tttgatttaa ctgaattatt
     1981 ataacacatt gcatcaatta ctgacgaatt tgacatcata atgaacggtt tttatttttc
     2041 ggcaataaaa acgtaacaaa attcatgctc acgtaaatag aaatcatgtt atgctttttt
     2101 aaaggaggga atagaatgga agattttttc tttgcaccat ttgattggat ttatgggtgg
     2161 cttacaggta aatagtttgg ttttcacttc ccaaaaacga aaaaaaagac tggccattct
     2221 tccagtcttt tttccgtttt ttttatttat tttttcagtt tcttaatcaa tgtaaaaaat
     2281 tctattttgc gggatcgatt ttatcatttt attggtcaag atttttccat ttccaatcca
     2341 atacttctgg cagatcaata ccattttcac gaatatagtt ttgatgttct tgtaatttct
     2401 gatccatttt tttcgcaaaa tcttctgctt gacttccttt gatttttaaa gctgcgtctt
     2461 ttgccaaatg ataacgatca agttcattta ctacacgcat gtcaaatggt gtcgtgatat
     2521 ctccattttc tttgtagcca tgaatcatta aatgatggtt atgacgatca aagaaaatcg
     2581 tgcggaccaa tgtttcataa ccgtggaaag caaataagat cggtttgtct tttgtaaaat
     2641 attgatcaaa ttcttcatcg ctcaacccac gcggatcttg acttggatga cgtaatttca
     2701 ataaatctac gacattgatg aaccgaattt ttagttttgg gaattcttcc agcagcaaag
     2761 ttacagctgc taatgcttct aagttagatt ccgttcctgc agcagcaatg accaattcag
     2821 gttcctcctc ttttgctgtc gaagcccaat caatgatttt caagccttca ttcactaaga
     2881 cggctgcttc ttctgctgag taaaattgag cacgcggatg tttggaagag atgatcaaat
     2941 tgattttttc tgacgagcgg aatgctttat ccatgactgc gagcaatgta tttgcatccg
     3001 caggcagata ttcacggatg aactccgcct tcttttctgc caaatgtgtc aatattcctg
     3061 gatcttggtg gctatatcca ttgtgatctt gctggaagac tgttgagctt gcaatgagat
     3121 ttagcgaagg ataatcattt cgccaagaaa ggtcatgtga tttccgcatc catttgaagt
     3181 gctgagtcaa catagagtca accactcgca agaatgattc gtaacttgca aaaaaccatg
     3241 ccgtccagtc agaacgtacc cttctaagaa cccttcatct tggtgttccg ataattgact
     3301 gtcgatgacg cgaccagatg gcgaaagcca ttcatcattt tctggttcga ttttttccat
     3361 ccattggcga tttgtcgttt tgaaaacttg attcaatcgg tttgattttg tttcatctgg
     3421 tccaaatata cggaaatttt ctggattttt ctcaatgatc tcgcgaacga atttaccaag
     3481 ttcggtcata tcttctgctt taacggagcc tggtttttca aattgcaaag tatatttttt
     3541 ccaatctggc ataataagcg gtcttggatc gattccacca ttggtgatag gattttttgc
     3601 cattctttgg tcaccagtag gcgcgatttc tctgatttct tctaaaatac gtccttgtgc
     3661 atcaaataat ttttctggtt cataggattt cagccaacgg agtaaagcat ctgcatgatc
     3721 catatgttct tgatctacag gaatcggtac ttggtgtgct cggaaggttc cttcaattgg
     3781 ttccccgtcc cattcttttg gaccggtcca tccttttggt gtgcgtacga tcaatactgg
     3841 ccattttggc atcacgacat ctgttgctgt cttcaggcga gcttcttttt ggatggattt
     3901 aattttctcg attgcttgat ccattttttc agccataaca ggatttaatt tttctgaatc
     3961 atttccttca ataaagaaag gttcccagcc aagtccgtta aagtaatttg ctaattctcc
     4021 atctgattta cgtgccaaga tcgttgggtt ggctattttt gcaccattta aatgaaggat
     4081 cggtaaaaca gctccatcta tcactggatt gataaagaca tttgagaacc agcttccagc
     4141 taaaggaccg gtttctgctt caccatcacc aatcacgaca gcagagatta cttcaggatt
     4201 gtctaataca gctccgactg catgtgaaag agagtatcca agctctccgc cttcatggat
     4261 agaacctggt gtttctggtg ctgcatgaga agcaatgcct ccaggaaatg aaaatcgttt
     4321 gaataatttt tgcattcctg tctcatcttc cgttacttct ggatagatct ctgtgtaact
     4381 tccatctaaa taagcattcg ataccatgac ttgtccgccg tgtcctggcc cttcaatata
     4441 aaacatgttc aaatcatatt tattgatgac tcggttcaaa tggacataaa taaaattttg
     4501 gccaggaatc gttccccaat gaccgattgg atgttttttg acatcttcgg gtttcagtgt
     4561 acgtctcagt aaggggttat ctttaagata aagttgccca acagaaagat aattagcagc
     4621 acgccaccaa gccgtcattt tatcaaagta ttctttacta gaataatcca tacataacac
     4681 tccttttcat tattactctt attctagcgc agatactccc aattgaaacc taataagcac
     4741 ttctgttcat ttgtttggat tttatatcta gccaaatgaa caggtataaa aaaccacgaa
     4801 atttttcctt tcgctgacgt tttttacatt gatccaaaaa acttgtcgtt atcacaatgg
     4861 ctgttccgca gttcatttcg ctcctcatca tgcataattt gctgaatgac gctgggccag
     4921 ttaacacatt gctggaaaac tggggctgga tcgagcaatt cctttcctga ttgatccgtt
     4981 ttatgtaaaa gtctctgtta tctttgtcaa tatgtgaatt ggtatcccag ctactatgct
     5041 aatttctaca gggattatcc aaaatttgga tcgtgaccaa atcgaagcgg cgtaatcgga
     5101 aatatcaata acttcaacgt gatttttctt ttaactgtca acggaccgac aaactcaaac
     5161 ttttatggtg caggttccac tgatcttcta gttacttggc tatacctgac tgtcactaaa
     5221 atagattaca atctagcttc cgttatcggt atcttgatct ttatctatat gcaaaaattt
     5281 atatactact agaaaaaaga aagtcgaatt ttttactttt ctttttctct tttttggtta
     5341 gctgacacgc cgcaagacta aagtcatgga actcttaggt aatacgtctt aatgaaaaca
     5401 aaaaaatccc gcaacccctg atttcacagg atttgcggga gtttttgatt agtctttgtt
     5461 caagtcgcga agcaattcat cgatatggtt gccatagaca actgattcat caagttcaaa
     5521 gaacaattca ggtgtcttat aaatacttag attgtgccct aactctcgac gaatcaatcc
     5581 tgatgcttta ttcaatccat cttgtgctgt tttcttatct gatgctaagt cagataaaat
     5641 gctgtaatag atcgttgctt gctgtaagtc ccccgtaact ttcacatctg tgatcgttac
     5701 gttctccaca cgagggtcac ggaccttttt gcgcaaaata tcattgactt cttttaagat
     5761 ttcttgaccg actcggcggt cacggtagtt agccataatg attggcctcc ttttatcagt
     5821 ttttagtcat ttttgacttc ttccatgata aatccttcaa ttacgtcatc tactttgatg
     5881 tcattgaatt tttcaatcat tgcaccacat tcataaccca ttttgacttc tttcacgtca
     5941 tctttgaatc gtttcagact tgcaagttgg ccttcataga ttacgattcc gtcacggatt
     6001 acacggacac cgctatctct acgaatatat ccttctgtta cataggcacc tgcaatcgta
     6061 ccaactttag aaactttgaa ggtttcacga acgatcattt gaccggtgat tttttcttca
     6121 aattcagggt ctagcatccc tttcatcgca gtttcgattt cttcgatggc tttatagatg
     6181 atacggtgaa gacgaatatc gacttcttca gtatcagctt gcacttttgc ctgcggtgta
     6241 ggacgaacgt tgaaaccgat gataatagcg ttgctggctg ctgctaaggt tacatcactt
     6301 tcattgattg ctccgacagc tgaatggacg atttttacac ggacaccttc cacatcaatc
     6361 ttcttcaatg atgcagccag tgcttctgct gaaccttgta catctgcttt gatgattacg
     6421 ttaacttctt tcaattcgcc ttctttcagg ctttcaaata agttatccaa agtcacacgg
     6481 cttgtggcag cacggttttc taataatgca cgtttcgcgc gttcttcacc cgctgcacgt
     6541 gctgtctttt cgtcttcgaa gactacgaaa cggtcacctg cttgaggtac atcattcaag
     6601 ccagtgattt ctactggcgt tgcaggtcct gcttctttat cgcgacggcc aagatcgttt
     6661 gtcattacac ggacacgtcc gtaagtatta ccgacaacga ttgggtcacc aacatgaagt
     6721 gttccttctt ggacaagtaa ggttgacaca ggacctttac ctttatcaag acgtgcttcg
     6781 atcactgttc cgattgcgcg ttgtgttgga tctgctttta aatcttctac ttctgcgact
     6841 aacaggatca tttccagcaa ttcttcgatg ttttggccga atttcgctga gatctcaaca
     6901 aagatcgttt ctccacccca tgcttcagga attaactcat actcacttaa ttcttgcata
     6961 acatgttgag ggtttgcacc tggtttatca attttattta cagcgacgat gattggaacg
     7021 cctgcagctt tggcatggtt gattgcttca actgtttgtg gcatgacgcc atcatctgca
     7081 gcaacaacta agatcgtgat atctgtgata cttgctccac gtgcacgcat acttgtaaag
     7141 gccgcatgtc ctggtgtatc caagaaagtg attggtttac catcaatatc gatctggtag
     7201 gcaccgatat gctgtgtgat tccgccggct tcgccgcttg ttacacgtga atggcgtaat
     7261 gtatccaata aagttgtttt cccatggtct acgtgtccca taatcgttac gactggcgga
     7321 cgtgagacta atttatctgg atcgacttct tctgcctcga agaatttatc gatatcagca
     7381 atgtcaactt ggactttttc ttgtggttcc atgccatagt ccgtcgctaa cagttcaatc
     7441 gtatctttat ccagtgcttg gttttgattg accatgacac caagcataaa taatttttta
     7501 atgatttctg ctggctcacg atgaattttt ttcgcaatat ctgctacgtt cataccttca
     7561 gtatactcta atacatctgg caattcacgg aatttgcgtg gtggtacagc tggtttagtt
     7621 gattgttgct gtttgccttt tttacctttt ttattataac gattacggtt attattatta
     7681 aatttgccgc gattgttatt gtttggtttg ttgttattgt tagtacggtt ttgattgccg
     7741 ccttggctcg ttccttgacg attttggctg ctggtatttc ccgtattatt ttggtttgtt
     7801 gttggttttt ttccttgatt cacttgaccg ctcccttgac cgcgatcttg ataactgcgg
     7861 ttatttttat ttttttgttg attgttcgtt gtttcttttt tacgttgatc gttcggctgt
     7921 tgattggctg gttttctgct tgcttgttgt gcagcttgtt gtttcgtgct tgggtttttg
     7981 aacgcttgtt gcaatttctt ctcatcattg ctagtaatcg cacccatatg gtttttcaca
     8041 tcgatgccaa gttgttgtgc tttttccacg acgtctttac tagatttttt gagttctttt
     8101 gctaattcat agattctttt gttgcccatg caatcacctt cctaaccttc aattagctcc
     8161 ttggtcttct tcgcaaatcc ggcatccatt attccgaata ccttgcgagg ttttccgatc
     8221 atctgcgtga tttctgcttc agaaaatagc tcaaagcaag gaacttcata atatgaactc
     8281 ttatctttta tcttttttct tgtattctcg cttgcatcgg ttgccacaaa caccaatttt
     8341 gctttttgtt tgcggatttc agcaatggtc agttcttcac ccgtgattag ttttcccgcg
     8401 cgcatcgcta gaccgatgag attcatggct ttttgccgat taactgtatt cattttccaa
     8461 ataactcttt acgtgctttt tggtgagtga catagtcaag aagttcttga taaaactcat
     8521 ctgttaatgt tgtttcgagt actcgatcga gaattttttt atcccaagct tgttgtactt
     8581 cttccggctc aagtgagaca tacgctcctc gtccaggcat ttttccagtt ggatcgatcg
     8641 atacttcccc ttcttttgaa cgggtgattc ggaccatctc ttttttaggt ttcatttcac
     8701 ctgaaaccac ggatttgcgt aaaggaattt tcctttgttt catctctttg cctccttact
     8761 aaagttaagc ttctggtttt tcttcgaccg tttcattgtt gaatgcaatt gtttcatatt
     8821 catcgtctgt taaatctgac tgaacgattg cttcatcatg cagttcttct gtttcttttt
     8881 gttgttcttg attttcataa aattccgtca tgtcagattc tgatttgata tcgattttat
     8941 ggttagtcaa tttagcagct aaacgtgcgt tttgtccgcg tttaccgatt gctagcgata
     9001 attggtagtc tggaacgaca actgtgcagg cctttggatt tgtctcatcg aagatcacat
     9061 ccatgacttg tgcaggattc aatgcatttg caatgaatac agctggatct tcattccatt
     9121 cgacgatatc catgttttcg ccttttaatt cattgacgat tgcttgaact cgttgtccct
     9181 ttggcccgac acatgtaccg actgcatcga tatttggatc atttgagcga actgccactt
     9241 ttgaacgatc gccagcttca cgggcgatgc tgacaatttc aacgattcca tcatagactt
     9301 ctggtacttc ttgctcaaat aagcggcgca ataggtctgg atggctgcgg ctaacaaata
     9361 cttgcggacc tttagacgta ttttctactc gggaaacata aactttgatt cgatcatgtg
     9421 gttgataaaa ttcatttggc atttgatctt gtttagaaag aactgcctca attttaccaa
     9481 gattgacata aatataacgt ttatcctggc gttcgacgat tccttgcatg atgtcttttt
     9541 cataagcact gaattcgtta taaataatcg ttctttctgc ttcacgtaca cgctgtaaaa
     9601 taacttgttt agccgtttgc gcagcgatcc gcccaaaatc ttttggtgtt acttcaaaac
     9661 ggatcgtatc accgatctca tatgctggat tgattaaaag tgcatctttc aatgagactt
     9721 ccaactgtga atccatcact tcttccgtta cttcttttac cgcatagaca tggatctttc
     9781 cttttttctg atcaaattcc acttcgacgt tttgtgcttg gccatagtga cgtttgtatg
     9841 cagaaaccaa tgctgcttct aaagcatcga tcacgatttc ttttgagatc cctttttcag
     9901 cttctaaagc gtctaacgca tttaacattt ctttactcat tttttctgat tcctctccgt
     9961 gattaaaatt ggatagctaa gcgagctttt gcaatatttt ttcggtcaaa agtcaattct
    10021 ttttctcgtg tttttatgcg tattttcaat gtaagctgtt cagcatcaaa tgattgaaga
    10081 aatccttcat attgtttttc gccatctact ggttggtata aggagacatg gacataatca
    10141 ccaagtgcct tttcatagtc gctttctttt ttcaatggcc gctctgctcc cggggaggat
    10201 acctccagga aataagcttg aggaatcgga tctggatctg ctgcatcaag tttttcactc
    10261 agtttctcac tgacaaaggc gcattcttcg atatcgatac cgccttcttt gtcaataaat
    10321 actcgtaaga accagctttt tccttctttt acaaattcga cttcgacaag ttcaaaattt
    10381 tgttcatcta aaatcggtgt caccatttct gtgactgttt caacgacgct actcaaaagt
    10441 ttcgcctcct taaaaaatta agtgcgtaat tccattaaaa agagtgagcg aaaaatccgc
    10501 tcactcacag ttagtatcat tacctataag aactatacca tactctgctt aaaattacaa
    10561 gcagacagga aaacagatgc ttatagcata tcgaataacg ataattgatt ttcatctggt
    10621 agatctttca atacgccatt gtcgttcata tattcgatca atgtttttga aactttaccg
    10681 cgggtggcaa gatcttcttt ggataaaaat ggaccgtctt ttcttgcttc aacgatttgt
    10741 tttgccacgt tggttcccaa acttgggaca gctctaaatg gtgcgatcaa cgtatcacct
    10801 tcaataacaa agttaacggc atccgattta tacaaatcaa tcattccaaa tttgaatcct
    10861 cgttccagca tttcattggc taactccagc actgtcagtt gattcttttc ttttacggaa
    10921 gcatctaatc ctttgtccgt gatttctttc attgcttgtt tcacagcatc ttttcctttg
    10981 cacatggaga ctagatcaaa gtcgtctgca cgtacagaaa agtatgcaca gtaatacaaa
    11041 atagggaaat aaaccttgaa ataagcgaca cgaagagcca tcaatacgta agctgcagca
    11101 tgggctttcg gaaacatata tttgattttt gaacaagaat cgatatacca gtcgggcaca
    11161 ttattttctt tcatcgccga tagataggtt tctcgcaatt catcagggat cttgttccat
    11221 tgtcctttac gaacagtttc catgatttta aatgccatcc cgctatctaa tccagcatgg
    11281 atcaaataaa ccataatatc atcacgacag ccgattactt ccgccagtgt cgcatctcct
    11341 cgtcgaatca attcttccgc atttcctaac catacgtctg taccatgaga tagtccggaa
    11401 atttgcagta gttctgcaaa agttgtagga tgcgtttctt ctagcatccc tcgaacaaaa
    11461 cgagtgccga attctggaat acctaatgtc cctgttttgg aataaatttg ttcctgactt
    11521 actccaagta cttcaggacc ggcaaatatc cgcatcactt ccgggtcatc cgtagggatc
    11581 gtttgtggat cgatccctga taaatcttga agcatccgaa taacagttgg gtcatcatgc
    11641 cctagaatat ctaatttcaa tacattatcg tgaatcgagt gaaaatcaaa atgagtcgtt
    11701 ttccattccg aattttgatc gtctgctgga tattggatcg gcgtaaaatc atagacatcc
    11761 atataatcgg gaataacgat gatcccccct ggatgctggc cggttgtccg tttgactcca
    11821 gtagcgcctt ttgctaatct gtcgacttct gcacttcgaa actgcagatt attgtccctt
    11881 tcgtatcctt ttacatagcc atatgctgtt ttgtcggcga ctgtaccaat cgttccggca
    11941 cggtaaacat agtcttcgcc aaacaatact ttcgtatagt tatgggcttc tgcttgataa
    12001 tcacctgaga agttcaaatc aatatcgggc actttgtctc catggaatcc taaaaatgtc
    12061 tcaaatggaa tatcatgacc gtctttgttt aagcgtgcac cacattttgg acattgtttt
    12121 tctggcatgt caaatccaga accatacgta ccatcttcaa aaaactcgga atattggcac
    12181 tctggacaat aataatgagg ggctaacgga ttaacttcag tgattcctgt catcgtcgca
    12241 acaaagctag agccaacaga gccacgtgaa cctactagat agccatcttc attactttta
    12301 tgcactagtt tttgggcgat cagataaata accgagaagc cattaccatt aatagaattc
    12361 aactcttttt ttaatcgttt ttgaatgatc tcaggtaacg gatctccgta catttgtttt
    12421 gcttttgtgt aactcaattc tgatatttca tcttctgaac ctggaatctt cggtgtataa
    12481 agttcatctt tgactggaat cacttcttcg cagatatctg cgattttatt cgtattttct
    12541 actacgatct ctttcgctgt ttcttcccct aaaaagtgaa atgcagttag catctcatcg
    12601 gttgttcgga aatggacatc cggcaaacta tgacgattca acggattcgc tccgcccata
    12661 gaattgatca aaatttttcg gtaaatggca tcttcttcgt tcagataatg tacattacct
    12721 gttgcaacaa cgattttatc caaacttttt ccgatttcta ccaaattttg gataatttct
    12781 tccaaatcat gttcattttt taccaattct tgctcgatca aaggcgcata gaccgctttt
    12841 ggcataactt caatataatc gtagaatttt gctcggtttc ttgcctcttc tacccctttt
    12901 tgcatcatgg cttcgaatat ttctccctta tcacaagctg agccgatcaa tagattttca
    12961 cgcatctttt tcaattggga gcgtggtatt cgtgggacgc gttcgaagta ttcgacattc
    13021 gacattgaaa tcagtttgaa caaatctttc agtcctgcct gattttttgc taaaatcgtt
    13081 acatggaaag gtcgagccct tttgtaagaa tctccttctc cgatatgctc atttagctga
    13141 tcatgataaa gcatgttatg attgtccatt gcctctttca caaagatcca tgctaagtga
    13201 ccagttgctt cagcatcata gattgctcgg tgatgctgtt ccaagctgac accaaatttt
    13261 ttagataaca cacctaatcc gaaacgtttg aattgaggat acagatatct agctaattcc
    13321 aacgtatcaa tgactggatt ggccgcttca ggaataccat accttgcgta gctagtattc
    13381 aagaacccca tatcaaaagc cgcgttgtgg gctaccaaaa ttgtatcttt tgaaaattca
    13441 aggaacatcc gcaatacttc ttcttccgac tttgatcctc gaaccattcc atccgtgata
    13501 ccagtcagat ctaccgttgt tcgtgacaaa ggatgtcctg gatcgataaa ttcatcaaag
    13561 ctttcgatca catttccttt atacattttg actgcggcta gctcgatgat cgtgtcatat
    13621 actgcagaca atcctgtcgt ttccacgtca aatacgacat atgtggcttc actcaatgct
    13681 tcatgtgcat cattataagc aattgggaca ccatcatcta cgacattcgc ttccacgccg
    13741 tataagattt tcacacctgc tttttttcca gcactatgtg cttccggaaa ggcttgcgca
    13801 ccaccgtggt ctgtaatggc gatagctcgg tgtccccatt tccctgcttg tgccacaaga
    13861 tcagagatgc tgtttgttgc atccatcgta ctcatattgc tatgaacatg aagctctact
    13921 cgtttttccc cttcaggagc ataatctttg cgaggtgtat gtttgacttc tatgatatct
    13981 tgcgcattca tgaccaaatc acggacaaac gtatcttctt gaatacttcc tcgtaccttt
    14041 aaccagctac cgacactgat cgcatcaaat acttgttcat ctttttcgcc gttcgagaat
    14101 tttttgacga taaatgatga agtataatct gtgattttca aagtcaagat cttgcgtttt
    14161 gaacgtagtt ctctgacttc tttgtcgaat acgtacccct caagtgtgac tcttcgttct
    14221 tcttcaacga tactgatcat tggtgtcgtt ggttcatcgg ctggaatatt tcgtcctagc
    14281 tggatgtgga tgggtccttc aagagctggc gattgctctt ttctttcctt tttcttttgt
    14341 tcgtggacaa ctagactttc agctgcttgc ttcataaagg cttctgcctg ttcttgtttg
    14401 cgttcttcaa aaagtttcaa tactcgttcc gcttgctgct catccacttc tggttcgata
    14461 cgaaattttg ggaatccgta actgacgaac aactcttcta ctaatggcaa gtattgttgc
    14521 ttcaaataag aaatagctcc tgtactgtcg attggcaaga tgactttacg atcttttatc
    14581 acaggtacct gcgttttcaa tacttgctgt gctagtggtg tatcgcattg ctgattttcc
    14641 aaagcttggg cccagtaatc ttgcaagagc tgttcatcga atgtctggtc atctgctaag
    14701 atattcagtt tgacttgtgc aatatcttta aaagcgatag tcagatgctg agtcaatgac
    14761 cgatatagca taataggcaa aattttggaa aaatgcagcg taaattccca taaacgcgat
    14821 ttacgatgga ccactacact atccatttca ccagcagtaa gcagtggatg atttttttct
    14881 gcttcctcta gttggatttg ttccaacagt ttttcaaata aatctcgttt ttctgacaaa
    14941 gatatacgcc ctttctgatg agaaacaatg caattgatcg catcttatcc tcttcttttt
    15001 cagtaccttt tagtatactc gttttttctg agttttacat taaaaaattg gaactgcgat
    15061 tcaaatcgca gttccaattt taaaagcgaa tcatcagatt gtcaaaaaca gctgattcag
    15121 ctatttttat tttctgtgtt ttaacgctta ttattcgcct tggttcaaga ggattggtaa
    15181 agtattcacc aattcttctt tacgtacttc aaccatttcg ccagttttct tgattttcac
    15241 ttctacgatt ccatccactg cttttttacc gacagtgatt ctgattggac agccaatcaa
    15301 atcagaatcc gcgaatttca ctcctgcgcg ttcatttctg tcatcaacca gtacttcata
    15361 gccagctttt gtcatcgctt cttctagttc attcgtcagg tttgtttggt attcgtcttt
    15421 tagattcatt tggacgatat gcaaatcaaa tggcgcaatt ccttttggcc agttgattcc
    15481 ttgttcatct gaatgttgtt ctacgattgc tgataataaa cgacttacac cgataccata
    15541 acagcccata atcacaaatt tttctcgtcc attttcgtct agtacagttg ctcccataga
    15601 ttcactgtaa cgagtgccga ttttgaagat atgtccgatt tcgattcctc gagtaaaggc
    15661 aagaacacca ttgttgtctg gtgaaggatc tccttcttgt acaaaacgaa gatcttcata
    15721 agaaagtaca gtgaaatcgc gttctggatt cacattttta tagtggaatc ctgtttcgtt
    15781 cgctccagta atggcattcg ctaaatcttg gacataacgg tctgcatata cttttacgtc
    15841 atctgaaaca ccgactggtc cgacagaacc aaactcagca cctagatatt tttgtgcttc
    15901 ttcttctgtt gcttcttcta aaaagtcagc agataaaaag tttttcagtt ttacgtcatt
    15961 gacttcatgg tctccgcgta ccaaaacaag gacaggttgt tcatccgcaa tgaacaatac
    16021 agacttgatg attttttgag gttcaacaga aaagaaatct gctacttcgt caattgattt
    16081 tacgttaggt gtagctactt tctccaattc aagctgtgtt tcatgcgatt tttttgatac
    16141 atagtagctt gtagccatct ccaagtttgc agcataatca ctttcagtcg aataacagat
    16201 cgtatcctcc ccgatttctg agatcgccat gaattctttt gagtctttcc cgcccattgc
    16261 gccaccgtct ccgataatcg agcgaaattc taagccacaa cgcttgaata cttcggtgta
    16321 ggctttttcg taatctttat atgtctcgtc caaactttct tccgttgcat ggaaagaata
    16381 cgcatctttc atgataaact ctcttccgcg aagcaaaccg aagcgaggtc gtttttcgtc
    16441 acgatattta ggttggattt gataaagatt taaaggtaat ttcttatatg aattgatttc
    16501 attacgcatc aaatcagtaa aagtttcttc gtgagttggt ccaaggatca tttttcgatc
    16561 attgcggtct ttgaaacgat acaagtttgg tccatatgtt tcgtaacgcc cggattcttc
    16621 ccaaagttct gctggcaaga tggcaggcat cagcatttct accgctccga ttttttcaaa
    16681 ttcttcccgc ataatgcgtt tcagtttttc caatacacga tttgctaatg gcagatatga
    16741 ataaataccc gctgatactt ggcggatata tccagctctt agcaagattt gatggcttaa
    16801 tacttctgca tcatttggaa cttcgcgtaa tgttggaatc aacatttttg attgtctcat
    16861 tctatatact cctttatttc ctcaaaatag ttatcgtttg ttattatacc ctatttgtca
    16921 actttttcta gaaaaagaat cgttgaatat cgttccatgt aactagcacc atcaacaaca
    16981 ttaaaaatcc aaagccagct aatgtcaata ttccttcttt ttcttgactt aatggtttcc
    17041 cgcgaatccc ttcaaaaata ttcaagacta atttcccgcc atctaaggca ggaatcggaa
    17101 gcagattgac gattccgaga ttcattgaaa gaagcgccat caaactaata acagttgtta
    17161 caccttgatt tgctgcttct gaagacaatt ggtacatcat gacaggtccg cctaatttat
    17221 ctaaactgaa acctgtaaat agtgatccta aggctttgaa aatttccaat gaaccgctga
    17281 aagcttgacg cgtccctcca atgatcttat ccataaaacc tgtattcatt ggggctttta
    17341 taccaagttg gccaactttt tcgccatttg actctacaga tttcggtgtc acgtcgacag
    17401 attgcacctg accttctcgt tcgatcttaa agtctaatgt tttatccgga tttttcgtaa
    17461 tgactgttgt cagatcattc catgaatgga tttcttttcc gtccacactg actacctcat
    17521 cattttcttt taagcctgct tctgccgcag ctccattagg catgatctct cctacgcgat
    17581 tagtgttcgt cacttgaaca ccaccttgca taaatgccag aatgatgaat aacaggattg
    17641 ccaaaataaa gttattcatg ggtccagcaa agttggtcag catacgctgc cacaatttag
    17701 ccgattggaa ctgtacgtct tttggcgcaa ttctgatttc tgttccgtcg ttttcaataa
    17761 tcgtcgcatc gtgatcaaca gggtaggtta ctacttctgt ttcgtctcca ttcacataac
    17821 cagtgatagt cagctcatct tctaaatcat aacggctcaa ttccatcggg atagcatttg
    17881 tcaattggat tttcttactt aaatttatct tctctacgat gccgtcagaa tttagtaaaa
    17941 gagaaagagg cattcctggt gccatttctg tttcatcatc cccattgcct gccattcgaa
    18001 cataaccgcc aataggtaat aggcgaagcg tatatgttgt cccgtctttt gcttgatgcc
    18061 cataaatttt cggacccata ccgatagcaa attcgcgaac gaggattcct gatcgtttcg
    18121 caaagaagaa atgaccaaac tcatgaacaa tcactaatat accaaaaacg atgataaatg
    18181 tcagaatcgt tttcatagct tttttctcct ttacttgttt tttgtgtttt ttataaaaca
    18241 acgataaaac actataattt taccatagta taccaaagac accaatagta tcaatataat
    18301 gaaaaataaa aacctgcgtc ttttatgaaa ttcacaaaga aacgcaggta tacttactaa
    18361 ataatgccaa ataaatgcat gataggaaat acaaacagca aactgtcgaa acggtctaag
    18421 attccaccat ggcctggtaa gatatttccc gagtctttca catcataatg acgtttgatt
    18481 gcagattcga ccaaatcacc aaattgtccg actgctgaaa aaataatcgt catcagaagc
    18541 atgacaaaca taccatgatt aaatagttct tttgctgggt atagcaataa ataaagaaat
    18601 gcgactacaa cagcactacc aataccaccg agcgcacctt caatcgtttt gttgggcgaa
    18661 atatcaggac ttaacttatg ctgaccataa cgtcgaccaa ccatatatgc tccgatatca
    18721 gttgcccaaa caataaatag accaaatatc aaaacagcca agctttctgt tcgtgcattg
    18781 acaaaattct ggaaacctat tcccacatac aagctgacaa gcacaggaaa acctgcttca
    18841 tcaatcgtat acgtattttt agaaataact gatgttccta aaagaatcat aactataaga
    18901 taaaataaca taaatgtact tacattctct ggaagaaaga aaaaccatct ttcttttggc
    18961 aaaacaagta acactgcacc aacggcggat aaaactcctt caaaacttaa gagtgtcaat
    19021 cctttcatcc gaaacagctc gtaaactcct attactgcta agattgctgc tgtaagctca
    19081 accgctatgc ctccgatcca tataatcgga ataaacaaga ctagcgccac ggctgctgtg
    19141 accacacgtt gtttcatgac tgatcccctt tctcatcttc tgtttttttt acaccgccga
    19201 atcgacggtc tcgattttga taagaggcga ttgcttcttc aagatgcgca ccatcaaaat
    19261 caggccaaag cgcttttgta aaatacagct cactatatgc gatctgccat aacagaaaat
    19321 tactaattcg ctcttctcca cttgtacgga tcatcagctc aggatcttgt aactctttag
    19381 gcaagaaacc tgtcattaaa tgcttagcaa tcaattcatc atcgatttct tctgcgtgta
    19441 tttctccttt tgctacttct tcggcaattt cttggacagc agtcacgatc tctgctctgc
    19501 ttccataatt caaagcaaaa ttcaatacca ttccagtatt gttttttgtt tgctcaattg
    19561 cacgtcttac agcatcttgc gtatgttctg gcaatacgtt ttcataaccc atgacatgaa
    19621 ctttgacatt ttctttaatc aattctggta cgaacgtatc aaagaagtcg acaggtagtt
    19681 gcatgagaaa acttacttca tcttttggtc gcttccagtt ttcagtcgaa aaggcataaa
    19741 gcgtcaacac tttcactcca agccttgatg ctttttttgt gactttcttt actgtttcca
    19801 tgccttcttt atggccagca actcgtggca aacgacggtt ttgcgcccaa cgaccattgc
    19861 cgtccatgat gatggcaatg tgctgaggaa ttggtccatc ggtattaaat tgaaattcgc
    19921 ttttttcttg aatatatttg tttttttgcg gaaaaaaacg taacattctt tttcctccta
    19981 tacttaaaag attcccacta tcttaagtat tatagcaata tctaactgtt tttcctatga
    20041 aatcattgtt tttttattta aaaactgaat aattttttct ttttttaatt tttaaataaa
    20101 agaaatataa ataaaaacag aggaagcgga atgatccgcc cctctgtttt tatgatttta
    20161 ttaaacttcc aataattctt tttctttatc agcagcgatc ttatctactt ctttgatgct
    20221 gttatctgtc aatgtttgta cgtctttttc taatccgcgc aaatcatctt cggtaatatc
    20281 accatttttt tgttgttttt tatattcatc gatcgcatca cgacggatgt tacgaatcgc
    20341 gatttttgca ttttctgctt cttttttaac atctttagct aattcttttc tgcgttcttc
    20401 tgtcagttgc gggataacta agcgaatgac atttccatca ttggttggac tgattccgat
    20461 atcacttgcc ataatagctt tttcaacatc ttgaagaatg ctcttgtcaa aaggtgtgat
    20521 cattaaaaca cgtgcttctg gaatttggat tgatgccatt tggttcaatg gtgttggcgc
    20581 accgtagtag ttcacagtaa tacggtccaa aaggctagcg ttcgcacggc ctgcgcggat
    20641 ttgcccaagt tcacgttgaa gattttgtgc tgcttttttc attttttctt ttgcttctgt
    20701 cataattgca tctgccattt ttatttcccc cttacagttg ttccgatatt ttcgcctaag
    20761 attgcacggc gaatatttcc gtgttcattt aaattgaaga caagcagtgg aatatcatta
    20821 tccatgctta gtgaacttgc agttgaatcc atgacttgta atcctttggc aataacttcc
    20881 agatgagtca gttcttcaaa ttttactgca tttgcatcta ctttcggatc agcagaataa
    20941 acaccgtcta cattgttttt agccatcagg ataacatctg cgccgatttc tgccgcgcgt
    21001 aatgctgctg ttgtgtctgt cgagaagtac gggttgccgg taccgcctgc aaagataacg
    21061 atccgtcctt tttctaaatg acgttctgct ttacggcgaa tatatggctc tgcgatttga
    21121 cgcatttcaa tcgaagtttg cacgcgtgtc ggtacaccca cgttttccaa cgtatcctgt
    21181 aaagctaagg cattcataac tgtagctaac atacccatgt aatcagcttg agcacgttcc
    21241 atgcccattt gtgctccgat ttgtccgcgc cagatatttc cgccgcccac aacgattgcc
    21301 atttcaacgc ccagctcgtg aacttctttg atttcttgga tgatttcttt gattactggt
    21361 ggtttgattc caaatcctgc gtccccagct aaagcttctc cactcaattt taagactaca
    21421 cgctgatatt tcggtgtgac catgttcatt cctccaatat tttctattgc cattttacca
    21481 tacttagatg atttcgacac tctaagactg gtttttcttg ttttgcttaa aaaaagggag
    21541 cgcacaaacc gtgcgttccc gtctgttatt caacagaatt attttttcac ttggctcata
    21601 acttcttcta caaagttatc ttcgcgtttt tcgatacctt cgccaacttc gaaacgtacg
    21661 aatgttttaa cagttgcgcc ttttgatgca acgtattttt caacagtcat atcaggatct
    21721 ttaacgaatg gttggtccac caaagcgatt tctgctttga atttcttcaa gcgtccttct
    21781 accatttttt caacgatatt cgctggtttg ccttcgttca atgcttgttc tgtaagaaca
    21841 gttttttcat gttctaattc agcttctgga atttgtgatt cgtttacata acgaggattg
    21901 atagctgcta cgtgcatagc tacgtctctt gcaactgttt cgtcagttgt tccatctaga
    21961 acagtcaata cggcaatacg tccgcccata tgcaagtatc caccaaatgc agcattgtcg
    22021 tctttttcta caacttcaaa gcgacggaag ctgatttttt ctccgataac ttgagttgct
    22081 tcgatcaagt cagattcaat tgtaccttta tctgttttga ttttcattgc agcttccatg
    22141 tctgctggtt tgttttcagc aacaagttct gcaatttctt ttactaaatc ttggaacatt
    22201 tcgtttttag aaacaaagtc tgtttctgag tttacttcaa cgattgctgc agtgttacct
    22261 ttcacagcaa ctgaagccaa tccttcagct gcaatgcggt catttttctt cgcagccttt
    22321 gccattcctt tttcacgtaa aagatcaact gctttttcca tgtcgccttc tacttcaact
    22381 aatgcttttt tcgcatccat cattcctacg ccagtcattt cgcgtagttc ttttaccatt
    22441 ttagctgtaa cgtctgccat gtttaactcc tcctgtgtgt ttttcttttt aaaaaaagct
    22501 gcttcaaagg agagtgaggc ttgtcgccca gcctttgaaa cagctccatc attcaaaatt
    22561 attctgctga agaattgtcg ccttcaacaa catctacgat ttcttcgatt gatgttgctg
    22621 tgttttcttc tgtgaaatct tcttcaacta cttgatcttc accttggttt ccttcgatga
    22681 aagcatcagc catttttgaa gtaatcaatt taacggcacg aattgcatcg tcgtttgaag
    22741 ggattactac gtcgatttca tctggatcgc agtttgtatc aaccatagct acgattggga
    22801 tatttaattt gtgtgcttct tgaacagcaa tacgttcttt acgtgggtca acgatgtaca
    22861 ttacatctgg gattcttggc atatcagcga taccgcctaa gaatttttca agacgttcac
    22921 gttctttgtt caaaccagca acttcttttt taggtagaac ttcaaaagtt ccatcttctt
    22981 ccattgcatt gatttgtttc aaacggctga tacgtttttg gatagtatcc cagtttgtca
    23041 atgttccgcc taaccaacga tggttaacga agtattgtcc tgcacgagtt gcttcttctt
    23101 tgattgcttc ttgtgcttgt ttttttgtac ctacgaataa tgctacgccg ccttcttcag
    23161 caacgctctt catgtaatca taagctgcat ctactaattt aactgttttt tgcaagtcaa
    23221 tgatgtagat tccgtttctt tctgtgaaga tatatttctt catttttgga ttccagcgac
    23281 gagtttggtg accaaagtgt acgccggctt ctagtaattg tttcatagaa attactgcca
    23341 tgtttgtttc ctccgatttg gttttatttt tcctcttctt atcttctacc ttgccggcaa
    23401 actttttcaa gcacctaccg acaatccaat aagaatgtgg atttgctgat gcataaagca
    23461 ccctcagcta ttatacagac aaaagatccg tatcgcaaga gcaaatatac ttttctgctc
    23521 aacattcaat agtttacctg aaagataaaa agaattcaag aaaaacagta gatttctctt
    23581 tgtttcttta ttatcctttt tccataaaat aattttaggt ataaaagacg aatattattg
    23641 ggcaatcctt cttttttttg ttatgataca tgtgaaatct ttcgtaaagg agaaagaaaa
    23701 tgcgcaaagc tcaaagacat ttgctgatta aacaagtcat tgaagaattc ccgatccgta
    23761 cgcaagaaga actattaaac aaacttgggc attatggcgt taccgccacg caggcaacga
    23821 tttctcgaga tatccgtgat ctaaaaatcg tgaaggcacc tgatgaaaat ggcgtttccc
    23881 gcttcgtatt gtttcgcgaa aaaggaactc ctgagactag gactgaggaa gaggatcggc
    23941 tggttcaaat gattgaagac attgtattga aagtcgaacg agtccacttt ttgacgatcg
    24001 tcaatacctt gccagacaat gctcatttat ttgcatctgt tttagatgag atcaaacctc
    24061 cctctattgt cagtacaatt gctggattcg atacgatcat ggtcatctcg gaaaatgagg
    24121 aggacgcaaa acgagtagaa gaatttcttc accatccaac tgaagtatca cttttttaat
    24181 cagagcacgt attcctaata tggaatgcgt gtttttttat tttcaatatt ttccttattg
    24241 aataaacctt tacactcttt acaaaaatac atcatttttt attcaaattt ttcaacacct
    24301 tgattgaatc acaataatca tcatttatat tggatgttaa caagagcagc ttcttgctct
    24361 ttgtgtattt caaaaaagaa atgaaaggaa atcatatgta taaattatta acttctggac
    24421 cattgacgac ttctgaaaca gtgaaaaatg ctatgctgat cgatcattgt acttgggatc
    24481 aagaatacaa agaaattaca caatggataa gaaaaaaatt attggatctt gctcaagtat
    24541 cggaaggaat atacacaacg gtcttaatgc aaggtagcag ctccttcggg gtagaatcgg
    24601 tattaagttc tgtgatcagg ccagaagata ctgtactgat ttgttcaaac ggcgcatata
    24661 gacaacgaat gatcaacatg tgcgaatgtc tgaaactgaa ctataccgtt tatgaggtat
    24721 cggaacatca aatcctccaa gctcatgtga ttacacagct gattgaagag aatccgtcta
    24781 tctccgcact agcaatggtc catagcgaga ctacttccgg tattttgaat aatttggaag
    24841 agattgctgc tgtcacacaa gaaagagatc ttttgtttat agtggacgcg atgtcaagct
    24901 ttggtgggat accgatttgt gtagccgaac tagggattga ttttttgatt tccagctcaa
    24961 acaaatgtat tcaaggtgtt ccaggctttt cttttgtact tgctaataaa gcggaactgg
    25021 aaaaacgaaa aaatgttagc cgaagtttgt cacttgatct atatgaccag taccgcgtga
    25081 tggaaaacga gaatggcaaa tggcgtttca cttcccctac ccatacggtt ttggcttttc
    25141 aacaagcgct gaaggaacta gaggcagaag gaggaatcga aactcgatat tcacgttatc
    25201 tcgccaataa tcatgtgcta cgacaaaaaa tgacagagat ggggttccag cctttcattc
    25261 aagaatatca ggggccattc atcacctctt ttctttaccc taaggactgg cgatttgatt
    25321 ttaatcattt ttatcagtat ttaaagcaaa atggatttgt gatctatccc gggaaaatca
    25381 gcgatcatga atgttttcgt atcggaaata ttggcgagat ctatccggaa gatattttgg
    25441 aactgacagc aattatcaaa gactataagg agaacgttaa tgattaaaac tgtaattttt
    25501 gattgggcag gaacaactgt ggactttggc tgtatggctc ctgtccacgc ttttagaaat
    25561 gcttttctag aaaaaggaat ccaactgact gacaaagaaa tccgctaacc gatgggaaaa
    25621 ttaaaatggg atcatatcca acagcttctt tccctccctt ctgtcaaaaa acaatggata
    25681 gctatttatg gacaactacc tcaggaaaaa gaggtggagg aattgtatca acaatttgaa
    25741 cattatctgt ttaaagattt ggtcaagcat tctaccttga aacccgacac attggaaacg
    25801 atcgaacggt tgagaaacgc tgggatcaat attggttcca cgaatggatt taatgctcct
    25861 atgatgacaa tcgtagcaga aaccgcaaaa aaagaaaggt attcaccaga cttcatggca
    25921 acttttgaag acgtcgaagg gtatggtcga ccgtttcctt atatgatcca taaaaacatg
    25981 cagtacttca aaaacaagtc ggttgatgaa gtaatcaaag tcggagatac ggtctcagat
    26041 atccaggaag ggaaaaatgc cggagtgttg acagtaggtg taattgaagg tagttcgcta
    26101 atggggattt cttatgatga gtaccaaaaa ttagagatgg ggaaaaagat cgtttaaaac
    26161 agtctgttgc tcttagattc caacaagccg gcgctgatat ttgtgtaaac aatttaaaag
    26221 agttaacaga atacattttg tacgctgaca tgaatccaga atgactttta tacaaaataa
    26281 gaggttgtga aaaagctgtc ctgtatcaag taataaaaac agccaagcaa aaatagctcc
    26341 tcatattttt cgtttggtta ggcttattac cgcagatgca agcttttgaa caccgtttat
    26401 tcgaaaaaaa aaagggagct gtgacacgac ttttgtcaca gtccccttat ttgcaaacaa
    26461 acagtgttta agagacaacc tctccactaa acggtgttca ttcagctgac tctcggtatt
    26521 tgctcaaaaa acgataaaat ttgaaaagct attttctctt ttgtttctct aatactcgga
    26581 tcagaacgct gatttcacat tctctttttc ttacatctta tctggtgcat gaagtcctag
    26641 caaacgaagg tcttctttca ataatacagt cactgcataa actagagcta agcgtgcttc
    26701 tttttgttca tcatcagcta aaatcttcgt atgagcatag tatttgttga atgcttgtgc
    26761 taatttgatt gcatgtttcg caatcactga cggttcgtat ttttccccag cagacaagac
    26821 cgtttcaggg tatttttgaa ctaatttaac cacttcccag ctggtatcgt cattcaatgc
    26881 atagtctgct gtttctgaag ggacaaatcc tgctttttcc aacaggctga ctgcacgagc
    26941 atgtgtatat tgcacataag gtccagtttc tccttcaaat cgaacaactt cttccaggtt
    27001 aaagtcaaat gtattcagtc gatcgttttt caaatcgtgg aaaatgactg ccccaacccc
    27061 aacttgttta gctacagcat ctttgttttc caaatcaggg tttttctcgc tgatttgttc
    27121 tttagcagat tggattgctt catttaatac ttcttctaat aagacgatct ttcctttacg
    27181 agttgataat tttttaccac cttgcgtgat caaaccaaat ggaatatggt gcatgtcgtc
    27241 agaccagtca aagcccattt ccttcaagac agctttcaac tgtttaaaat gatagctttg
    27301 ttcattccct actacatata gagattgttt gaagtcgtaa gtacgtttac ggtacaatgc
    27361 agcagctaag tcacgtgtaa tgtatagtgt cgcaccgtct gacttcttaa tcaacgctgg
    27421 attcaggtca taagcagata ggtcaacgat ctctgcacct ttatcctcgt tcagcaaatg
    27481 tttttcttct aaaagtttga cgatttcatc catcttgtca ttgtagaaag cttcaccgtt
    27541 caacgaatcg aaacgtactt ccagcagatc atagatttta ttgaattctt tcatcgattc
    27601 atcacggaac cattgccata attgaatagc ctctttatcg ccttcttcca gacgtttgaa
    27661 ccaagcacga gcttcttcat ttaattctgg ttctgtttca gctacttcat ggaattggac
    27721 gtataaacga agcaattcat tgattggttc tgctttaaca gcttcttctg taccccattt
    27781 tttgtaagcg acgatcagtt ttccaaactg tgttccccag tcacctaaat ggttgatgcg
    27841 gattggctga taaccgattt tttccataat gaaaccgatc gaattaccga taactgtcga
    27901 acgcaaatgt cccattgaga ttggtttggc aatattagga gaagacatgt cgattggtac
    27961 tgttccttga ttcccgatgt tgctatcccc ataatgttct ttttctttca ctactgtttg
    28021 caaaactttt ttgctgataa gttctttatt catgaaaaag ttcaagtaag gtccgacaac
    28081 ttcgattttt tcaaagttgg cagaatcgat tttttctgct aaatctgcag cgatttgctg
    28141 tggcgctttt cggtaaactt ttgctaatga aaaggctgga aatgcaacat ctccgtgttc
    28201 agctgatttt ggattttcta gtaattgctc gacttgttcc agtgttaaat catctttgac
    28261 agcgtcatag acagcttttg cgacaagatc tttattattc atctttattc ctcctaaagt
    28321 gttcccttga ttgttaaaca aaaaaaatct ctagcgacgg catacttagt atgccatcac
    28381 tagagacgag atttcccgcg gtaccactcc aattgtccta aaaaaggacc agctccatct
    28441 gatatcggta gacgaccgtc tgtttaaaac agaattctcc aagtgcgctt cgttgtatct
    28501 tcttcattcg gcttccacca cttccgaatt cgctagccaa gaatgataca agtactctct
    28561 tgttcaacaa atcttagtct tattaaactt tcttgaatta tatcagaaaa aaaaacgaaa
    28621 ggctagtcgt ttcataaaaa aacaatccag atggcctaaa ggagaagaaa taccacctgg
    28681 atagctataa atcatttcgt aaatacgaaa gacttaacaa attaatcagc tacgataatc
    28741 gttccttctt cagaagctaa aagattctcg atattttcta aagaagtgat gattgcctta
    28801 gcgtttggtt ttgcttcaac aaatgcaata gctgcttcta ctttcggaag catgcttcct
    28861 ggagcgaatt gcttttcatc aatgtattgt ttcatttctg aaacagtaac agtttctaat
    28921 ttcttttgat ctggtttttg gtaattgaca tacacattgt ctactcctgt caatacgatc
    28981 agcaaatccg catcgatgat ttcggctaat ttttctgaag caaaatcttt atcgattacg
    29041 gcttctcgtc cttctaatcc agtagctgtt tctacaacag gaatcccacc gccaccaaca
    29101 gagactgtga taactccttg atcgaccagc gtttcgatga cacgtgcttc tttaatcgag
    29161 atgggtttag gggaagcgac tacttttctc catccacgtc cagcatcttc tttgaatgtc
    29221 acagtggagt cagcattcat ttgttctttg gcttcttctt ccgtgtagaa tggaccgact
    29281 ggtttacttg gatttttgaa tgaaggatca ttttcatcca caataacttg agtgactaaa
    29341 gaaaccacat ctttatcgat ccctttttcc ttcagtactt cgcccatggc gttttgtaac
    29401 cagtaaccga tagatccttc tgtcattgca acacatgtat ctaaaggcat tgccggtgtt
    29461 ttctcagaat cagcagcttg ctgctgaatc aataggttac cgacttgcgg accatttccg
    29521 tgggagatga tcaattcatc tccttgttcg ataaatttca ctaaatactt tgctgtttcc
    29581 attaacgctt cttgttgggc ttttgcactt gcatccgtag acaagatggc attgccccct
    29641 aaagcgacaa ctacttttcg tttggccatt tcattcgtcc tttcttcagt tctaccgaat
    29701 tttctagata acaaaacgag ccagcgtttt gtgattttcc ctcaatgctg actcgttttt
    29761 tcgtgagatg aatgtggtta tgcttaaacg cgagggataa acaagttacc taatgttgct
    29821 gccatgatcg ctttgattga gtgcatacga ttttctgctt ggtcaaattg acgagcatat
    29881 ttgctgcgga agacttcatc tgttacttcc atttcagtga tgccaaagcg ttctttcatt
    29941 tgttcaccgt aaacagtgtt tgtatcatgg aaagctggca agcagtgcaa gaagatcaaa
    30001 cgatctgtgt tgtgtgtttt ttctaccatt tccatattga tttggtaagg tttcaacaat
    30061 ttgatacgtt cttcgaattt atcttcttca cccattgata cccatacatc agaataaagg
    30121 acgtctgctc cgtctacacc tttatcaaca tcgtcggtaa tcatcaattg tgcaccggat
    30181 ttttcagcaa agccttctgc cattttgacg atttcttctt caggttgtaa ttcttttggt
    30241 gcaacgatac gcatattcgc tcctaaaatt gcacctgtga ctaataaaga gttagccata
    30301 ttgtttcgac catctccgca gtaagcaaca gtgatacctt ctactgttcc aaagttttct
    30361 tggatagtta aaaagtcagc gatcatttgt gttggatgcc attcatcagt caagccattc
    30421 caaactggaa caccagagaa ttctgctagt tcctctacca ttttttgact gaatccacgg
    30481 aattcgattc cgtcaaacat acgtcctagt actttagctg tatcttctgt ggattctttt
    30541 ttacctaatt ggatatcatt tgcacctaga tattcaggat gtgcacctag atcgatcgct
    30601 gcagtagtaa atgcagaacg agtacgtgta gatgtttttt caaataaaag cgcaatattt
    30661 tttccttcta gatagtgatg tgggatacca cgttttttca agtctttcaa gtgttctgaa
    30721 aaatcgatca aatattgtaa ttcttctttt gtaaagtctt tttctgctaa taagcttctt
    30781 ccttggaata ctgattcttt catattaaac attctccttt agattgtttt tatttaagat
    30841 taaagaggaa atcccgacgg cagctgacag taagactgcc gtcaggaaac aaattacttc
    30901 aagtcttcac ggacaagtgg ttggctcatg cagcgtggac caccacgacc tcgtgacaat
    30961 tcacttgaat tgatttctaa cactttgatg ccatagctac gaagcaattc gttcgataca
    31021 taatttcggt tataagtgac tacaacacct ggagcgattg ccaatgtgtt tgatccatca
    31081 ttccattgtt ctcgaggtgc aacgatctca tctccattac cagttgggat cagtacaaga
    31141 tcatctaatc caagagcagc tttcatcgtt tcgtgtaagt tatctgaatg agtaatcttg
    31201 atatcatcac catctggttc gattgtaaag acatccatct taccgtcttt actttgaatt
    31261 gctggatgga tagtgaattt atcgtgatct accattgtaa atacggtatc caaatgcatc
    31321 attgcacggt tgttcggaat tttgattgcc aacacttttt caaatcctga attttttgcg
    31381 aataggtggc gtgctaattt ttctaaagct ttcgcattag ttcgttgaga aatcccaaca
    31441 gctactactt tatcgcttaa gatcaattcg tctccgcctt cgatatgatc tggattttca
    31501 cgatccaacc atacttcgat tcctttattt gcaaatcttg gatgatgttt caaaatatat
    31561 tctgtaaaca tcgattcacg acgacgtgct tcaaaagtca tcttattgac tgtcatccca
    31621 tttcccattg atgcggaagg gtcgcgtgta aagtacaagt ttggcattgg gtccatgtaa
    31681 aatggatagt catcgtctgc tgacagatca tatagactgc tagaacgtac ttcgatatct
    31741 tttgtacgaa ccccagccat gattttatct accatttctt gcgtttccat tgatagaagg
    31801 aactcatgaa gaccctctct tacagcattc gatgcaatat gagattcatc caacatttta
    31861 ttcaagaatt gttctttgac attgcctgcg tcaatcgctt ctgccgctaa tttttccaag
    31921 taaagagtct cgacgccttc attttgcaat gtcttcgcaa agttgtcatg ttcttcttga
    31981 gcaatcggaa gatatggaat atcatcgaac aacagacgat ccataatatc tggtgtcaaa
    32041 ttttccactt cttgtccagg ccgtttcagt aaaactgtct ttaatttccc tatttcagag
    32101 aaaacgtgaa taggtttatc catgttgtgt tgcctccttc tttttgatta catgtatagg
    32161 atatcctcct tttgtaatca ctttcataat tttgtctcat tcaaaatgag acattcctca
    32221 cattaatatt cgataattaa ataattaaac gtttttctat ttttaagcgt aatttattca
    32281 ttttttattc tgtatacact ttcaaaaaaa tatttattca ttgaaaaaat ttttttgaat
    32341 aaattaaaaa aataaattat attatcgttg ttagcgttta ctatatgtat tattgttgtt
    32401 ttttatacac aaatcattcg cttcaaaaca aattattcaa taccattgta tattttttac
    32461 ataataacaa attatatttg taaagtatta aaacttgttt ctaatgttgg tatgttaaaa
    32521 ctttacaaat tctttaaaaa aagtgacaat aaatatagtg aacaataagg agaggacttt
    32581 ttaatgcgtg ttaataaaat cgattttcac ttttcaaaac tcagatatca acctgatttt
    32641 gaacatttct cggatgaaga gttccaacag atcaaggaac atactgttct tcgttcttat
    32701 aaaaaaggac agatcctttt cgacgatggt gatcccagac aacggttgta tatcttgacc
    32761 aaaggactcg ttcgtttaga acgttatgat gaaagtgcaa cttattacta ctatgactat
    32821 gtgaatacaa ataacctttt tcctatgtca ggaatgtttg gagaagagac ctacacttat
    32881 acagctcaag cgatgactga tattgaaaca ttctaccttc ctgtttccta ctatgaaaaa
    32941 ttagcacgaa aaaatcccga acagttgatc tatatgatac aaaaaatttc taaagtagtt
    33001 gaaatacatg aattgcgtat ccaaatcgga ttgacctcta gcgcctttga ccgggtaaaa
    33061 caaaatttat tcattttgaa agaagaattg ggcgtaccaa caaaagatgg tcatatcacc
    33121 attccttatc cgatcacctt aaaagaatta gcagtgaata gcggcacgac acgtgaaact
    33181 gctggacaag taatcaaaca actacgtgat tccgggctgt tagattatga caaaaagcgt
    33241 tttactttct gtaagacagc tactactcca gctatgagag aataacgcga acaaaaataa
    33301 gcagtgaccc tgataaatat cagggtcact gcttattttc ctccctaaaa cttctgaaag
    33361 atccggcagt tttagatcac tggacaagac tcaaagattt tctatgtgtg tttcagttat
    33421 gtaatattca ctgtttgcaa aaaatactgt tagattaact agatgaagcg tcttgtcctc
    33481 atccgatcta gattattcga tattcctcga caataaacga ttactcagtg agggcaatca
    33541 gaggaacgga taatgataaa taagctgtaa aaaatagcaa aataacaata atgattaaaa
    33601 gtatgtaaaa aatagggctt tgacaaaaac gtgtcacagc cctatttcga ttaaacggtg
    33661 tgtacctgtc aactcttcgg tcacaagtca taatgttcat aaacatgagg agctgttttt
    33721 tgaaattgtt ccttgtgaat cagagttaaa cgacaggctt acgaactctt gattaaacgg
    33781 cgttcaaaag cttgcatacg cggtaataag aacagccagg tcaaaaacat gagaagccgt
    33841 ttttcctggg ctgttcttat tacttgatgc agggcagctt tttcacaacc tctttattca
    33901 gataaaacca agcttggatc agcattcaac tgatagctag caaaatttct tttttgcatt
    33961 tccacatgtg ctgctgctcc aatcattgca gcattatctc cacaaagtcg aagaggggga
    34021 atcactagtt ctacctcagg gagtttagct gccaaagcat cctgcaatcc ttcacgcaac
    34081 ccttgattgg ccgctacacc tccagctata atcagttgct tgactggata attttgacaa
    34141 gctcgaagtg ttttagtaat caatacatcg atcacacttg cttgaaagct agctgctaaa
    34201 tcatttttgt ctagatcttc tccacgctgt tgtgcattat gcaccaaatt gataaatgca
    34261 ctttttaatc cgctaaaact gaaatcataa ttatcttcat ggatcatcgc tcgcggaaaa
    34321 tggtaattat cttttccctg atgagctagc tgatcgattt cttttccgct tgggtaagaa
    34381 agacctaata ctcttccaac tttgtcataa gcttctcctg ctgcgtcatc tcttgtctcc
    34441 ccaatgattt catatgatcc atcttcttgc atatagacta attctgtatg tcctccgcta
    34501 acaagaagtg ccatcaatgg aaactggaat ggtttaacca gacgggctgc atagatatgc
    34561 cctgccatat ggtttacagg aataagcggc aattggtgtg cccaagcaaa agccttagct
    34621 gcagaaatac caatcagcaa cgagccgaca agtcctggtc cataagtgac agcgactgcc
    34681 gataaatctt ctgccgacac accagcttct accagtgcat cttccaagca taaggtgatt
    34741 tgttctacgt gatggcggct agctacttca ggtactacgc caccaaaacg tttatgactg
    34801 tttatttgag aagcaacgat gttagataag atctctgttc catttctaac gaccgctaca
    34861 ctcgtttcat cacaacttga ttcaatcgcc agaatcaatt cttcattcat ttcatcgtct
    34921 ccgtttttaa ctttctgctc ataatgatcg catcttccgt cggattgcga taatatgatt
    34981 tccgtttacc taatatacga aacttttctg attcataaag ttttcttgct gcttcattag
    35041 atagacgtac ttctaaaaaa acatgcagcg aatcttttat ttgttccgta atcagtaatt
    35101 gtaacaaatg ccgtgcatgc ccttttcctt gttctgaaac tgcaacagca atatttgtga
    35161 tctcgacttc atctattact ttcgagtatc caataaagcc acagatctgg ttatcttcag
    35221 ctaaaagcag ataatcagag tgaggctgtt ggatgtctgc caaaaactgc attttcgtcc
    35281 aaggtgaacc atgtggataa gcattttcgc taatcatcca tacgcattct gccaagtacg
    35341 cttcatcaaa atcttttttt ctgcaaatca actaatctca ctcattttct aaaagtttta
    35401 tcatatccaa cgcatcttct tttgtttcag tgtaatatct ttttttgatc gttgttgctt
    35461 gaaaccccaa tttccgataa agtctttgtg catcttgatt actcatacgc acttctaatg
    35521 acatcgtctc acagcgattc attatagcaa agttctcgat ttcgtcaata agcagcgaac
    35581 cgattcgttt acgctgatat gccggtcgaa cggcaatatt cgtgatatgg caatctaaac
    35641 cgaacgctct tgaaccgata aaaccaatca ttcttccatt atcaaagata cctagatata
    35701 gatgaggaag cggtgacttc aattctgata taaaggcact ttttgtccat ggcaattcgc
    35761 cattatagac ttctcgttcg acatccagca gctctttgat atcttctgta gtcaattctc
    35821 ttagtacgta acgacgatcg atttgttcga ctgttttttc tgtataaatc attttatctt
    35881 gaaaaaagct tctggcatac gctctaaatt ttttcaacat aactttcgtc tccaggtgtg
    35941 tgcgtctcca accatttttc ttctgcttct actcgtttta aatagcgagg aagaaaagct
    36001 tgtttctctg caactggttc aactaaagca cctaattgag ccacagttac accacttgga
    36061 atatcccatg ctggaactgt attaatcatc gcactaggca atatttcctt tatttcagag
    36121 aagaatttgt gacaatcact cccgacgaaa taaatagctt cattcagctt ttgtagttgt
    36181 gtgaacaaat cagaagcaga aatatgtaca tcttcaagta cagtttctaa tctattttct
    36241 ttccagcggt atgccccagc gtatacattt tttcttcgag catcaaacat gggcacaata
    36301 atattatcca caccgatgca attagccgcg atggttttca gactagatac tcctactagc
    36361 tctttatcta atgtataagc aatcgttttt gctgtcgtta cacctatacg aagccctgta
    36421 taagaaccgg gaccatcaga aaccgcgatt cggtcaatgt cttttggact tatttgaaga
    36481 tctgcaaaca attggtcgat tgcaggcatc agtgttacac tgtggttgcg tttgatattt
    36541 gtttgtattt gtccaagaat ttgttcgtct tctaccacac cgatcgccaa agtttggttt
    36601 gcagtatcta ttcctaatgt aatcatatat ttgatccttt ctgctatgac attctcgcct
    36661 tccattgtag catacttttt tattctgagg atgaaaatac caaaggcaaa actagtacaa
    36721 taatacatga ttatctgctg gcgggcaaat tttgcccctt cctgaaacac aaaaaagctg
    36781 cggtatcact ccattttccc acagcttttc catcttttat ttcgttgatt ctcgaataat
    36841 caactctgtt tccacaataa tctttcttga aaccggtgct ttggaattac ttaattgaag
    36901 aatcgtctcc actgctagct ctcccatcca ttcggtataa acttttacag tagaaagcga
    36961 gggcgttaca tatttcgcta cactgacatc attgaagccc atcacagaaa tatcttctgg
    37021 taccactaaa cctttttctt gaatcgcttt cagtgcgcca atcgctaatg catcattagc
    37081 tgcaaaaagc gcatcaggaa catgcggatt cgtttttaaa tattgcttca ctgcttgata
    37141 tcctgactcg acagaaaaat ctgcttcgat aattggacct tcgtcgtagc ctttttctgc
    37201 caaaacttgt tgaaatgcca taattctggg atcttttagc cgctgatggt ttttcttcgt
    37261 atattctgtt ccagcaagca tagcgatatg ttgcgcttta tgggagacaa agtgttcaat
    37321 gactttttga acacttgact taaagtcgac aactagagag tcgattcctt gagaagtgcc
    37381 gtcagaatct accaaaagca aggcattttg ggatcctttc atttctaata actgagcttc
    37441 gtcgaatttt cctagtgcga tcgttccatc tgccggaaga tcactaatgg aatcccacgt
    37501 ttctttcaat aaagtaacgt ttgcttcttc tgcctttttt tcgattccta ggcgaataga
    37561 taaataataa agatcttcaa gctcttccgt atcgtcgtac cactggatca ggcgaagcgt
    37621 ttgcttagta tttgctgcat ttttacgatg tttcgtataa tttaagcgtt ctgctgcttc
    37681 aaaaattttt tgctttgtgg ctaagccaac ggaaagatca ggatcatagt tgagaactct
    37741 tgaaacagta gcaggagaaa ctcctgccaa ctgcgcaatg tctttaattg ttgccatttg
    37801 tctctcctcc ttttttacgt ttataaaatc gcagtaaatc gttcaaacgc tgcctgtcct
    37861 ttttcatctc gcttgaatac tccagcgtct tccagtacac gtgcaaaaac ctgacctaca
    37921 gatttttgta cgacatcggt gaccgtatct ttcgtcaaat caggatgttc tttttttaat
    37981 tgttctgccc acggacgatg atattcagcc atctggtttt cttctcctaa taagaaatgc
    38041 tctacttcta ctagttctgg tttcaaacga ggtggtaaaa cagcaagccc cattacttcg
    38101 atcaacccaa tgttctcctt tttgatatgt tggacatctt tatgtggatg aaaaatccca
    38161 tcaggatgtt cttctgaaac attgttgtct cgaaggacaa ggtccaactc aaagtaattg
    38221 tcccttcttc gtgcaattgg cgtaatcgta tggtgtggtg taccatctgc tgaaaaagct
    38281 ctgatagata ctgtttcatc cgaatatgct ttccattttt ccaatactga gttagctgct
    38341 tcaataagca agtttttctc tgttgattgc aaacggatca cagacatcgg ccatttcacg
    38401 actcctgcga tgacttgcgg ataatcttct agtttgataa gtttttctat cggtgctttt
    38461 gccataggaa attcatgacg tcctgcctga taatgatcat gagaaagaat cgatcctcca
    38521 acaattggta agtcagcatt cgaaccaaca aagtaatgag gcaagacttc agtaatccga
    38581 agcagtctag caaatgtttc ctttgtgatt ttcatcgggc ggtgttgttc tgataaaatg
    38641 atcgaatgtt cattgtaata agcataaggg gaatattgga atccccagct ttcaccgtct
    38701 agattcattc gaataatccg gtgattggtg cgggctggat agttcaagcg acctctatat
    38761 ccttcgtttt ccatgcaaag catgcaggta ggatagtcta cttttaccgc ctcgcgttct
    38821 gctgcgattt gttttggatc tttttctggc ttagataaat tgattgtgat ttccagttca
    38881 ccatactccg actctgccgg aaatttgatg ttttttgcga tggctcttgt tttgatgtag
    38941 tcatttttct tacttaaatt aaagaaatac tcagttgctt cctctgggct tttcgaatag
    39001 tgctgtgcaa agaatgcatt gacgactgaa ggtggcggtg tgagaaaatc cattaattgc
    39061 gcttcaaaaa tctcttgttc tgctggcaat tctgaaagaa caccattttc tcttgcctta
    39121 gcgacaagct gatccaataa gtctacagat tcttccttaa ctggtcttac ttcaatgctt
    39181 tctagagcat cttctcctac catccctaaa agacgattct gtaaatataa gcggtccatt
    39241 tccatccatc cgccagcttc gatcgcaagt gtggcaaaat cacaaatcgt ttgactgatt
    39301 gacatatctc attcccctat tcttcataac catttggatg gctgacatgc caatcccatg
    39361 ctgttttgat aatcgctttg atatctgtgt attcaggttt ccagcccaga atctctctcg
    39421 ctttttcact tgaagcgact aatcggctag gatctccagc tcttcttggt gctatttctg
    39481 ctggaatttc ttttcctgtc acttctctag ctgcttctag catttccttg actgagtatc
    39541 ctttgctgct gcctaaattg aagaagttgc tttcatttcc ttctttcaag tattccaaag
    39601 ctaaaatatg tgcagcaatc aaatcttcta cttgaacata atctctgata catgttccat
    39661 ctggtgtatc ataatcgtct ccataaacag ccaaggcttt tctttgacca agagctactt
    39721 gtaaaatgat tgggacaaga tgcgtttctg gtgtatgatc ttctccgata gatgcatctg
    39781 cttttgctcc ggctacattg aagtagcgca aagcgacata gcgcatgcca tatgcttggt
    39841 cacaccactt catcattttt tccatcatca atttactttc accatacgga tttttaggat
    39901 tagctggtgt atcttctgtg attggagact ctttcggctc tccataagtt gctgcagtag
    39961 aagagaatac gattttattc acgttgaact cgtgcatgac ttcaagtaag atttgcatac
    40021 cgtatacgtt gttgttgaaa tacatcaatg gtttttcgac agattctcct actaaagagc
    40081 ttgcagcaaa atggattact ccttcaatcg gttccttttc aaatacggaa cgtagaaatt
    40141 ctttatcccg gatgtctcct tcataaaaat gagcatctgg atgtactgct tgtttgtgac
    40201 ctgtgagcaa attatctacc acagctactt gatacccctt ttgaactagc tggtctacag
    40261 cgtgcgaacc gatataaccg gctccgccta gtactaaaat tgtcataaaa aacactcctt
    40321 tgattagtaa aattgtgttt gttgattcta tataatttaa aaaacgaagt ttacttttat
    40381 ggtgaaaaca aacaaagtaa aatttcgtaa attcatatgg taaatttata ataaaacatt
    40441 tagtaaacat tttcaagggt tttttgcaaa ggtttacaaa caaacgtaaa actagccttt
    40501 ttttctcttt tgttccataa tagatataac aaataataaa tgaggtggat tcaatgaaaa
    40561 aatttgtatc tggaatatta gtaggaagtc tggcaacagc cgctgccgtt gctggtttgg
    40621 ttgcttctgt gaaaaaaaca gtgatcgatc caattgacga aaaagaagca atgatcgaag
    40681 aaaaccgtaa aaaagcaatg cgtaaacgcg tttctcgtta ataattattt aaaaatacgc
    40741 atgaagactt tctaaaaaac agataagtca tcatgcgtat ttttatttgt cagtcaatat
    40801 aagttgtgct attttatctg cctgtctcag attccatgga tctgtataag gtctagctac
    40861 tgctgcagtt agccaatcca caccttcaac aggtattcca tagcaataaa agtcagactg
    40921 gatttcccct gaagcatcaa tcacgcgatt cgtacctcgc tcaacatcta tagcttctga
    40981 atgataactt cctgtattat ctgaaaatga aaaagggcga acaagtttgt tttccttcaa
    41041 attttttatg acaggattac ttgaacgaga aaagcttgtt tgtggcaatc gagcttcaat
    41101 caaatagcga ctgctgattt ctttatcttg tagagaaata acatagcggt tgtgcttttg
    41161 ctgaatatca aatggcggtt cgatcaaatg aaaaataccc gcatctatca gtgctgctaa
    41221 ttctttcgtc cgaatgattg gcggaccgat cgttaaaaag ctatttagat gagtaaacca
    41281 tccccatagt atttctttgt attccttagc agaaaaaacg tgccattcaa tagcctgccg
    41341 gattggatca cgccagtctt ttaatgcatc aaatgttgaa gcaaatgctc ctgtgcaatt
    41401 gcctttttcc gcttctttta tctgcccttc aataaatatt cggctagctt ctgaaaaggg
    41461 ctcattctga taggcaagag gagtttctaa atacgaccaa tcccatctat aagggattag
    41521 tgctggatgc tttccgagac actcctctga agagagggag agaaaatcat gctcaaaatt
    41581 tttctttgga atcggcaagt gatattcttc gatgattttc ttgtaataaa acaactcaac
    41641 gtcttttttc agatagtcaa aaaatgtttc gccagtcaaa aatcccgact gatgccattg
    41701 ctccaggttt tcttttgtta gtaaccgtgg ccatgccatt gctccgcctt gcttttgatt
    41761 tcttcctcga gggtaataag ggagccccct tcttgatcca ctgtatacaa tcggttcctt
    41821 gcctgatgga tgatagacca gttttccctt ttcgttctcg aagcgccctc ctcttgatac
    41881 tgtaaacaat ccgacataat caaaaaaact taagcctaga cctcttaaaa agacattttc
    41941 tttaggcggt atcttcgaaa gatctacatc tgcaggatta gaaggaagct gatacagtaa
    42001 aacatttttc tttgcgtagt ctacccacac tctttcttct tctgtctcat cattttccca
    42061 gtgaccgctt gctaaaacaa gctgatcgat agaatagctt tgctgatctg tctgtaaaag
    42121 ataaccatct tttcttttgc ttactttttt tactaaagaa taaacaaact gaatagaagc
    42181 tggaaattct tcttgcaact ttgagaaaaa ccagcgttga tagagtccgt ataaacatcg
    42241 agtagattgc tgatcttttt ccagacgatt gatttcttct ataattagtt gcttattttt
    42301 ggttaccgtc tgttcgatat aatctgtagc aggtccttta ctccattgaa acaagttggg
    42361 tccctgtgtt accaatcctc cactggacaa tgtttcatct gtaaaaagcg tcacttgttg
    42421 agaaacagaa ttcattaata actccggtgg ctgattcaac cgccaaactc gacctccagg
    42481 accattggga tcgaaaagaa aaagttcaag agaatgtctg tcctgattat tatggagaat
    42541 cctttctgct acacttaatc ctctaggtcc ggcaccaatg atccctattt tcatttgcat
    42601 gcctccattt cgataaattt tttcaataaa acagcatggt tctgatgttc attttttgca
    42661 ccataaacaa aagtaatgac tggatgttct ttcataagtt gactgagttt aaaaatagct
    42721 tgcttctttt cttcttcgaa aatcaattct tgctggtatt tctttgcaaa tgaagcaaat
    42781 cgttctggta catggtcaaa agttttgcgt gcttcattac taggtgcaat ttctttcaac
    42841 cacagatcta actgcgcttt ttcttttgaa attcctcgtg gccagaatct atccacgagt
    42901 attctatagc catcctcttt ttcagcatca aggtaaacac gttttaattt gatcatagtt
    42961 gtttccttct ttctaccttt tcgcttagct tatatatgta gataatagca caaaataaaa
    43021 aaaatgaacg gcacaactat ccattgcgcc gttcatgtga tcttggtcaa aatctaatga
    43081 ttgattcggt ttttaaagct gtcatacaat catctgtttt atactttttt acttttgatt
    43141 tttccagacc atccgtcata tccaccctta agtaaataaa tctcttgata acctgcttta
    43201 cgtaatttat ttgctgtacg gatgctcaaa cttttctttt gatcgtaaat atagacaggc
    43261 tggtcttttc gaatagatcc taatgaatct ttcaaaacag tgtaagggat gtttcttgca
    43321 cctaaaatat gcccagcatc aaacacatct ttttcgcgaa catcgattac ttgtgctttt
    43381 ctcattcctt ctcgaaattc ttcttctgtc aaagtcgttg ctgaacgttt ggccattact
    43441 cgtagataga cttcccaaag gatgattgca agcacaatca atagcaaaat gatattaatt
    43501 acccataaaa ccatgtaatg cctccgtttt tttaagcaaa tttcaaggct aatgaggcag
    43561 caccaatgac accagcttca ttaccaagct ctgctaattt gatttttgtt gattctctta
    43621 cttgcgggaa agtaaattct ttaaaatatt tctctacacg gctacgtaaa aattctcctg
    43681 ctgccgatac tcctccacct aacacgatac ttgacggatt taatgtattc cccaagtttc
    43741 cgcaagctaa acctaagtag aagcatacgc gatcaacaac catcaatgca aacggatcgt
    43801 cttcttgagc catttcaaag atatctttac ttgttacttc ttctccgttg tctagcattg
    43861 ctttcagttt tgaatcccct gcgtattctt ctgccaagaa acgacctagg cgtaccacac
    43921 ctgtagcgct agatacagtt tctaaacatc cgcgtttacc gcaagtacat tcgaaccctt
    43981 caggatccac agtgatatgt ccgatttctc ctccagctcc gctcacgccg tgaatcaaat
    44041 ttccgccagc aacgatacct ccgccaacac ctgttcctag agtaacgaat acaacgtctg
    44101 gatcgttttc tccagcacct ttccatcgtt cacctaaagc agcaacattc gcgtcattat
    44161 cgatagcgaa tttgattcct gttcctgcct cgatcagttt tttcacaaat tgaacttctg
    44221 tccagtttaa gttatacgca ccaataaccg ttccagcttc gctgtccacg cttcctgggg
    44281 tacccatgcc gattccgata aagtcttcgg ctttcatatt atataaattc aaacgatgat
    44341 tgattgattc aatgatttca ggaacgatat gcttaccatc atccaaaata ttggtatcga
    44401 tgctccattt ttgctgaatc tctccttctg gtgttaaaat tgcaaatttt gctgttgttc
    44461 cacctaaatc aatcccaata atcttcttgt ccattacaaa tttcctttct ttcggctttc
    44521 ttcaattcgg tgctctcttt ttaatatgcg ccacgctgtc atgtatgtat catgatcaat
    44581 caaacggcta tcatacagat tacgcaattc gatagtcatt aattcaatgt catagatgcg
    44641 tgcacccaca tagataaaga tgccaaattt tttgaacagc tgctgtacat catataagct
    44701 ctccatcttt aagcacttcc ttcatattat acaagtaaac catatttttt taaacccagt
    44761 aaaatacata ttacaaaaag aaatacaaaa actagtgtag aaagaatcct ttggtgtatc
    44821 gaatagcttg tctgttgttt cggtagaccc aaaacattcc ctaacactaa tccgccaatt
    44881 agcccaccga catgtcccca aacatctaca gaggtatcca gaagaccaaa aacaaatgtc
    44941 aacacaataa ataaaagaaa atgtctgact agctgctgga tcgctgggtt atgtttaaaa
    45001 tgaaacccta agataaacaa cgcaccgaac aaaccgaata tcgaagtact tgcaccacca
    45061 gacagaacat tcgcttcgtt aaaagcaaag cttgctgtat ttcccattat cccgctgaac
    45121 atataaatca agaaaaaacg ccaatggcca tagattgcct cgatttgctg ccccataaaa
    45181 tacagtatca gtgagttcat tacgaaatgc atcagtccaa aatggatgaa gattggtgtc
    45241 actaaacgcc accattcatt gaagtgaaca agataaggac catacattcc ggcataataa
    45301 gggatctcaa gtcgcggaaa taattccatc atgaggaaga ccgctgtctg tatccctaaa
    45361 aaagcatagg tccataacgg tcgtcttaac catgcacgca attttatttg ctgttgataa
    45421 ttcatgaaaa cctcccattt cattttagtc aataaacaat tgttggatct tctgatcaaa
    45481 gctctccggt tgccattgtt cattcaattg ttcacgaaaa acaaggctac atgttttttt
    45541 atgaaaatta tttaaatacc ggtcgtaata accaccgcca aaaccgattc gataaccggc
    45601 tctattgtag ataatacctg gtacaatgag gagatcgatc atctccggca aatagagctt
    45661 ctctgattgt ggctcaagaa caccaaaact cgaacgtaca agaacggact gttcatccat
    45721 ttcataaaac gccatctgac gtttcggcaa agttttaggt acaactattt tcttttgttc
    45781 tttttctgct cgttggataa ccggctgtgt atccagttca aattcattcg ataaagtcgt
    45841 ccctatcact tttgctgact tccagtactc gctggcgaat agctgtttat agattcgctg
    45901 ttctttttcc tttttcttgc cacttttggc cagatttttc agcttttcga ttcctttccg
    45961 gcgtaatctt actttcaatt ggtccaaaaa ctcacccttc cttctctcat aaaatggtat
    46021 aggaaaaaaa gaaaaatagc aatcgaactt tcaaataaat gcataaatag aataaaaaga
    46081 agacctagaa atgattggcc ttcctttttt aatgaatttc aactgttcag cgcgtgtttt
    46141 tgtctgataa aaagtgcata cagaaaatat ggcgcaccaa aaagggcaat caaaattcct
    46201 gtaggtactt ccccacttgg tagaatcact ctagcaacca tatctgcact aagcagaaaa
    46261 atggaaccga acaaaccgct cagaacaaag gtccagttat tttctttacg tacgactagc
    46321 ttcgcagcat gaggagctag tagtcctaca aaagataaac tacctgtcac cgctacacta
    46381 ccgcttgcca aagcaacagc taacaacaaa aggatttttt gacttttagc cacgttaagg
    46441 cctaatcctt gcgcgcgttc ttgaccaaat gatagcaata caatcctctg tgcataaagt
    46501 cctcctagcg gaattaagat aaccgcccat ggaagcaatg cccaaacata aggccagctc
    46561 gcaccccaga ttgatcccgc taaccatgca ttcacaaatc cataattttc cttagataat
    46621 tggatcgtgc atagcaatgt taatgcagaa aggccggcat taacggcaat accggacaat
    46681 aagattcgat tcatacccaa aaagccattt cgatcatagg ccgcaagata gacacagcaa
    46741 gcagctaaaa caccacctag aaaggctaca actagcaata gaaacggcag cgaatagtgc
    46801 gaaaagaaac ctaaataaag catcactaaa aatcctgctc cggcattaat gcccaatata
    46861 ctagaatctg ccaattcatt tcttgttact ccttgcaaga tataaccaga aacgccaaga
    46921 caagctcctg ctaataaact gatcagtaat cgaggaactc gaaattctct aacaatcagc
    46981 gccaaagaag atgattcttt ccctatgaac gtggcaaaaa gctgatccag gtaaataaaa
    47041 ggcgtaccaa tcattaaact acctatagac aggatgacaa gtacaaaaag caagaaatag
    47101 aacgtccaat atattttttt caccgttgtt ccctccttac ttgtatcagt aaaaacggaa
    47161 cgccaatcaa tgcaatgact aatccaaaag gtgtttcaaa agggggattg atcatcctcg
    47221 ctgtaaaatc cgccaacata accaatccac cgccaactaa aaaagagaca ggtagaacat
    47281 aacgatagtc cgttccaacc attccgcgaa caactggcgg aaccaacagc ccaataaatg
    47341 aaacaggtcc gactaacgaa acggcaatgg ctgctaacac tgcaactaga cagaaaacaa
    47401 tcaaccgcgt tcgtttagga tgacttccaa gagctaatgc atgtgtttca ctcaaatgaa
    47461 tcaaagatat tgcttttcct aatgaaaaag aaaccaaaac agcaagtata tataaaggaa
    47521 acaatactgc taattgtttc catgtgatat tggcagctcc gcctacaaac caaaaagcaa
    47581 gatcctgctg cagattaaag aattgggtaa gtgcttggct gatagcagta aaaaaagaac
    47641 taatagctac gccagctaaa atcagctgta aaggattcat gcccattttc gaaaactgca
    47701 aaaaaccaaa tacgagcaaa gttacagcaa aagaacctgc caatgacatt agaaacacag
    47761 aaaaatcaga agctttaggc caaaaagcaa aactaagggc cattgccaac gaagcacccg
    47821 cgttgattcc tagtaagcct gaatctgcta aaggatttct tgtcactcct tgcatcaatg
    47881 caccgctcaa tgcaaaacaa ctccctacaa gaaatgctcc cgccacacga ggcaaacgaa
    47941 tatttcgtat gatttggtga ctttgttttg atctatcaaa atcaaacaac gcctgccaaa
    48001 aatctgcttt ttccacagtc gctgcgccat ttgaaagagc aacaaaaaaa ataatcaaaa
    48061 gaacaaaaca gaccaaaagc aggagtctat ttttcttcat agtcctcata attgatcctc
    48121 ctgctctttt ggcaacaaat cataggttag aaaaactggt ttatttgttc ttggaagcgt
    48181 gacaatcgtt gcatcaatct caaatatttt tttcatacac tcttttgtga tcacttcttc
    48241 aggtgtacct tctgtgatca acttaccgtt tttcattgct aataaataat ctgaaaaacg
    48301 tgaagcatga ttaatgtcat gaatcgacat caagatcgtt gtttgtttca tttgattgat
    48361 ttcagtcaat aactgtagga tctctaattg gtgtgccgga tctaaaaatg ttgtcggttc
    48421 atccaagatc aagatatctg tttcctgagc aagcgccata gcgatccaga cacgctgggt
    48481 ttgtccacca gacagcgttg cgatatcccg catacgaaat ccagctagac ctgtagcatc
    48541 caacgcccac tcaattgctt catgatcttg cgtgtccatg ccactgaaca gtttttgata
    48601 agggtatcgt ccgtaagata ctacttcttc tactgtcata cctgtagggt gttcactagt
    48661 ttgtgctaat aatgcaattt tttttgcaag ttcttttgaa ctgtatgtag agatatcaga
    48721 gttattgaca atgatctttc ctgatttcac aggtagtata cgggtaaaac ttttcaataa
    48781 agtagatttt ccacttccat ttggcccaat caaactagtg attttccctt caggaatcgt
    48841 aacagacatg ttttcaatga tttttttgtt ttcgtagccg gctgcaatgt cagctgctct
    48901 taatctcgtc atttcaccca tcctttcgct gaaaatcatt ctcaattatg acgctgtttc
    48961 aacatttcgt caagcgctac tttcatatct atagccaaat gaagcggttg acagcgttcg
    49021 aaatatcagg aataataacc aatgagaaag attctcaatt atgttaggag gaaagaaatg
    49081 aaattaaaaa caaaagtatt cacattatct agcatattgc tgctggctgg agtactgagc
    49141 gcttgctccc cctcttcaga taaagaaaca gctacaactg ccaattcgac gacttcatcc
    49201 aatagtactc atacagtcac agatacactt ggacataaag tagagattcc aaacgcgccc
    49261 aaacggatca tcggcagtta cttagaagac tatctgattg cactagggga aaaacctatc
    49321 gcccagtgga ctgttggcag tggttccatt caagattatc tgcaagatga tttaaaggat
    49381 gtcccaacga tttcttatga ccttccttat gagaaagtgt taagctttga gcctgatttg
    49441 ctgttgattt cttcttccgc tactgtcgaa ggcgggaaat acgaacaata tagcaaaatc
    49501 gcgccaactt atgttgtaaa aaacggaaca gatgtcacat gggaagaaca actaaaagat
    49561 gtcggcaaag ctttggcaaa agaaaaagag gcagaaaaaa tcatttccga ttatcaaaaa
    49621 tccatcaaga aaactcgaga agaactagca gataaaatcg agaacaagac agctgcagtg
    49681 ttgtgggtga ccaacaactc agcctttatg gtcagcaaaa atcggtcaag tggaagaatc
    49741 gtatacgacg atctggaatt tggtgttcct gatctagtgg aagaggtctc caaaaaagcc
    49801 acttctgact ggtctgctgt ttcctctgaa aagctagctg aattagatgc tgactacatc
    49861 atccttgtga acagtgacaa agatgctgcc atgttcaatg aaccaagctg gaagaatcta
    49921 aaagcagtga cagacaatca tgtactgcaa ttcggacctg aatctagttg gctatataac
    49981 ggacctattg ccagtcagga aatggtcaat gatatcaaag aaaaactaaa ttgattttaa
    50041 ctaaaaaaag catcttcacg attagtcgtg agatgctttt tttcttatta acaaactaga
    50101 cgcatagatt ttattcttct tttgaagcaa ccctattttt tactctttcc catttttgaa
    50161 aacgatgggc atatagattt tcttgatccg ttatcccctc atactcctct ataagggcga
    50221 agtctgaaaa atcaatattc ccaatatacg tatcgccttc aaacgtgcta tcgatcaatg
    50281 ttcgccagat ccgaccagtg taaggaagaa gttcttgaaa aatccgacta ccacccgaaa
    50341 catagatatc ttctgagatc gtttgactat acgacaaaag ttcatcgatc gaatgcatta
    50401 cttccgcatt ttctttcgtg cgaaaatttg gttgcgttgt caacacgatg atatggcgat
    50461 aaggaagtga aagatccccc attccttcat aggtctttct tcccatcact aaaattcgat
    50521 ccattgtatg ttcgcgaaag aaacgcatat catttggcaa tcgccatggt aacaaaccat
    50581 ttttgccgat cagaccattt ttatcttgtg cccacatgga aataaacata ttatccgctc
    50641 cttatgattt tagatgtttt gagataaaaa aagtctcaat tctttgacca gcaaggaatt
    50701 gagaacttta aaaacattat tttgtttcac ggtgcaaagt aactttgcgt tcgcgtgggc
    50761 aatatttttg tttttccaaa cgatcaggat tgttacgttt gtttttgctt gttagatagt
    50821 tacgttcttt acaagaagta cactctaaag tgatgtttac gcgcatgttt ttccctccca
    50881 tttttacaag aatcctctaa gatgactctc agacttgatt atcttaccat gattttttct
    50941 agattgctag tgtttttcac gattttgtta agtaaaacta cttgacgata aatacaacgg
    51001 ttttacttct caaacaaaat ctttttcttt ttgtataaat acccttacac ttgtttatat
    51061 agattatgtt ttttaataaa gggggatact aatatgccat ggaacatgaa ggactttcct
    51121 gcatcaatga aaaacttaga taaattgaca agaaaaaaag caatcgacat cgcaaatgca
    51181 ttattagatg aagggtaccc tgataaccgt gcgatcccaa ttgccattga tcaagcaaaa
    51241 aaatggtatg aagatgctag tgaatcagaa aaacgaactt tcgaaaaaga aaaaaatcca
    51301 agcaagacgg atgaacacga tacgaatcct cgtgctggaa aactgcttga ttcagatgtg
    51361 atcgtagaat atgaggaaga acaatggatc gtgaaatcta aaggggcaaa aaaggcaagc
    51421 aaccattttg atacaaaaaa agaagcaatc gaaaaaggaa agcaagtagc acaaaacaaa
    51481 gaatcaactt tgttcattta taaaaaagat gggacaaaag aaaaagaaat cgattattga
    51541 acatatgtaa aggggttgtg acgaaaatcg tgtcacaacc cccttatgtt cgaaacaatg
    51601 gtgttcctct gccaactccg aaccataagt cataatatct ataaaacggg aagagctgtt
    51661 ttttgaaatt gtttcttatc actcagtgtt aaacggtagg agaaaacctc ttttttattg
    51721 atatttgatt ttcatcaaac agtcacatag tcgattgctt ctgcttgcgg aatcgtttca
    51781 tctacaaagt agactttata ccatgtcaag aaactgaaga ttgtccagat ttttctttgc
    51841 tcttctttac gtccttcgtg atggtcatct agcaacttca tgattttttc ttgatcaaaa
    51901 aattcttttg caaaatctgc ttcgaataat gctttgactt gttcgtagcc gtgttcttct
    51961 ttcaaccaag ctttgattgg cacagggaat cctaatttca cacgattcga ccattcttcc
    52021 ggaagatgtt tgttcgcagc ttgtctgaaa atatcttttg tgttgttttg attcaataaa
    52081 aacttacttg gtatttgttg agccaatttc atgacttcga tatccaataa aggtactcgg
    52141 acttccaaag aacttgccat agaaagttta tctgccttta acaagatatc ttttggcatc
    52201 cattgatgaa gatcgacata ttgcatctta ttgacttcat ctttgattcc ttctgttttc
    52261 tcgtaatgaa cagtcatgat ttcatccaca gatggtgctg tttgatattt tggtgttaac
    52321 acttctgatg cttctgattc ttcgaacact cgagcatgac cgataaaata ttcttttgca
    52381 ggagcaagtg attcatataa atggatccgt ccatggaagt ttttcatttt tccgatttta
    52441 cgtcctaaat tatagcgtgt tccttttggt aattttttca atccttgagc aatcacacgg
    52501 atgaattttg aattcgtatg gaatccatac gtttggtatc ccgcaaacag ttcatccgcc
    52561 ccttctccag attggactac ccgcacactt tgtgaagcaa gatttgctaa aaagtacaaa
    52621 ggtacgcaag aaggatttga atcaggttca tctaagtgat actggatcaa agggaatgct
    52681 ttgaacgaca tgtctccgtc gatcactgct gctgtattat ctaagtccaa tagttcggtt
    52741 agttttctgg cttcaatcgc ttcattatag gttttatcat caaacccgat tgagaaagaa
    52801 tgatctggtt tcaatacaga ggttacataa ctggaatcaa ccccgctgga taagaaagaa
    52861 ccaacttcta catcactgac cgtatgtgct tcaatagaag cttgaacggt ttcgtcgatt
    52921 ttttcgatcc attcttgtcg ggaatgcgtt tcttttgttt caaaatctgc atcccaatat
    52981 tgctgaatgt ctatttttcc atctttatac gtataataat ggccttcagg caaacgatag
    53041 acatctttga agaatgtttc gccgtttaat ggagaatatt ggaaagtcat ataaggtttc
    53101 aacgcttctt tgttcaattc tttgttaaaa tcaggatgag gcagaaaact tttgatttct
    53161 gaaccaaaca taaatgttcc gttcatttct gcataataat atggtttgat cccaaagtgg
    53221 tctcttgcac cgaataactc attcttttca ttatcccaaa tagcaaaagc aaacattccg
    53281 cggatctttt gcaataattc tgttccccat tcttcgtaac catgcaaaag gacttctgta
    53341 tctgcatgtg tttgaaaaac gtggccagct gcaatcaatt cttctctcaa aggctggtaa
    53401 ttatagattt cgccattaaa aataatgatc tttgtccgat cttcattgta aataggctga
    53461 gtaccgccct ctaagtcaat aatacttaat cttctgaatc ctaaagcaac atgtttatcg
    53521 atatattctc ctgaactatt aggtccacgg tgaacgattc gatccatcat tgtattaata
    53581 attgtttttt tgttgtcctt gtcgttaaca aaacctacaa taccgcacat ttaactttca
    53641 catcctaata taaaattact gtttatttca ttcatatgca tcttatcata gaataaatag
    53701 cggacgaata ttttctctct tacaatttcg tcacgtgaaa acaaaagatg aaagtttctg
    53761 tttttacaga aaataaagtc ccaatatcta atttaccatg ttttcttttt tgaggctacc
    53821 ttattctctt cgtgttaaaa aaatattagt ggatgctatt tccaaaaaaa ccagcaaaaa
    53881 aagacacgac ctaaagatcg tg
//
LOCUS       DBBGSP010000014        51481 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000014 DBBGSP010000000
VERSION     DBBGSP010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 51481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.014"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            476..730
                     /locus_tag="ACIZE9_000983"
     CDS             476..730
                     /locus_tag="ACIZE9_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092863.1"
                     /translation="MYNVGDQIDEIVKIGNVKLVKSKYYISETEIIFNTESGCILIWK
                     LPFPKDETTLKKINTLKIRYCIHEIIDKNTYVINQVKVMG"
     gene            1127..2728
                     /locus_tag="ACIZE9_000984"
     CDS             1127..2728
                     /locus_tag="ACIZE9_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HGC6092864.1"
                     /translation="MLNSCEYADVLAKILKNGIKQFNSKNLVAFKKNSNKIGAIAGFT
                     SKTNMIKTKGLIYRSIDRVLEDSDVLTHWTPNVYSWLGGGENKTIFGHKEANLIQINT
                     FVADIDYPVGEKKTDLNLLVLYLLEEGLLPTLIVDTPKGYHCYFLIQNYNQETDSFDK
                     ASYISNSNDFKSLRVAKRISENIRKSIQNRLPQVDMGCNHFGIFRFPTKKNIVHYEPN
                     FVDTFEGYLKWSKDFEEKEYALKRSNLSLLAPNSTGKKGSKRQIDTKWYDFLIHTDIA
                     EGDRNKTIFTLALACKSSGLSIGECMDQLDQLQFNNDLSYSEVERTIRSAYRGDYKGA
                     KSSYVNEIIENYATPTEFEKYSINVNRQAVKRKGNRVDPSNWVKFAKPREERKYSHFE
                     ESKADLLAYLERKQRSLKKNELFLSVSMGTISEETQIPVSTLKVILKELRTANTVILR
                     TSRGRYGSTKIATSKFVEAKILNTVIQNKKDKQVFVLELLGTANSHVETILRRYEDKT
                     VPFHANILKEREKSKHAPIRGANTG"
     gene            2962..3261
                     /locus_tag="ACIZE9_000985"
     CDS             2962..3261
                     /locus_tag="ACIZE9_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HGC6092865.1"
                     /translation="MVIKKYVYSHPINVFIIGKLGLSVEVFCELYGFKQGTLSSWITR
                     EREVADLPISFLYALSLASGGNMNEVYDCLCEYEKEYKEYLKISAPKRNKKYIED"
     gene            3396..3773
                     /locus_tag="ACIZE9_000986"
     CDS             3396..3773
                     /locus_tag="ACIZE9_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HGC6092866.1"
                     /translation="MNIDGIYNESDFKKGIVDIDRKEYLFPDEIGLFKIVGETVCRYW
                     GKKGNIILLVDTIEGRKLKFSFWSNTKYCCEPVPKREVDVAKESVRFLPDRSKITLIC
                     ERTSNAKFTRIRDILLSTTSSQS"
     gene            3822..6185
                     /locus_tag="ACIZE9_000987"
     CDS             3822..6185
                     /locus_tag="ACIZE9_000987"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HGC6092867.1"
                     /translation="MAVVILAEKPDQGAKFASALAGKKLSKKSGKYEFKSEIFGDTIV
                     TWGIGHLVGLSLPEKYEWLPNKDKWHLDNLPFLPKFNELKYEVSKGKNQQFSIVKSCL
                     ENADEIIIATDPDREGENIAYNIFKLCKQSIFNKPIKRLWINSLVQKEIIKGFKNLRN
                     SEETISYFKEANARQIADYLVGMNYTELYSLKLQEKGISGVVSLGRVQTPVNTLVVEN
                     DLAIRNFRPEKYKTIECHTTDKQPKAIFKNSLEYFKLEKFEEDTKKFGLDSASTGIIK
                     KIEVSKKQTEPQKLFSLGGIQEYANKKWKYSAKKTDKIIQSLYDRGYLSYPRTDSELI
                     TTNEFEYLKANLDVYKSVLGISIDTPCLEPKKRFVDNDKVLEHYALIPTMDIPDIANL
                     TLDEKNIYEIVTRRACLMFAEPYKYENTKVTLDVNGLEFTTSGNVPISLGWKQVDTNL
                     DESDDKEETLPKFHEQETINIDIRFIDKLTKEPKRLTEGKLLGKTGIMAKLGLGTPAT
                     RSNIVDTLLNREYIKIENTNVYPTPKGYLLWDLTKNKDLLIGKPENTAIWEESLGKIA
                     QGSYTQEAFLRNIYNYINKTVSDLKKVEFTSDYLEKTVNQNKFDIGSYQVEEKKKVYS
                     ILNITSGEQFVIFKNISGKAINKKVLQELLLNNRTDKVLSGFKSKEGKAFNARLLFDP
                     NVMKVVMEFEKNSPKGDKKSKHDTVNGYEIVEKAKVFEIKELATGESFIFYKNNSGKT
                     LSSKTVKELLENGKTKEKVTGFISKDNKKYSAYLVFDNKNKVIKKEF"
     gene            6503..7102
                     /locus_tag="ACIZE9_000988"
     CDS             6503..7102
                     /locus_tag="ACIZE9_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type III toxin-antitoxin system ToxN/AbiQ family
                     toxin"
                     /protein_id="HGC6092868.1"
                     /translation="MNLKNTNSNKSTLYVISDDYINKLKKVDYRVQNNYREQRLYFKS
                     NLKISNKNEEINYYVPLASAKENQRSLTNKSVFKIYGDREEKDFLGVLHINNMIPVPK
                     DCAKVWTPNSPNVDEKYKMLVIKQAKYLKLHESEINESCELLYNSKLGKLDPSYFKKN
                     RKEVITYQKIMTNVESLEAVSIAESQRNIHVQTQSIDVE"
     gene            7223..7438
                     /locus_tag="ACIZE9_000989"
     CDS             7223..7438
                     /locus_tag="ACIZE9_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092869.1"
                     /translation="MARPRKYNTEEERKEAMKKARKKWVEKNQETIAYIRAKSFAKKF
                     IEMSEDEDIELLEKWLEDRKNNGQNDE"
     gene            7820..8026
                     /locus_tag="ACIZE9_000990"
     CDS             7820..8026
                     /locus_tag="ACIZE9_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092870.1"
                     /translation="MIENRVLGFVECKDNLDDTLEVLESIIFNTKVLDLKAINGDMTT
                     HIILDEISAKEIGETLIAWANKEL"
     gene            8106..8960
                     /locus_tag="ACIZE9_000991"
     CDS             8106..8960
                     /locus_tag="ACIZE9_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HGC6092871.1"
                     /translation="MMKSNFLGYVIAINMFKGGVGKSTLTQLMADILSARGFKVLVID
                     VDPQGTVTKKFQRQYDLKVVGKMTLFEAVINMSFLDCISPVKENLDIVLGSEQMSRFT
                     KVLRDMWRSTGFTDEGEEVFWNLFNYMIGNDNLRDQYDFILFDTIPTVSEFTDNVYVA
                     SDFLVIPTQTEQDSIDNLHSTVTNYQTAVKEVNGDLEILGIVPYLVDTKLKTGLELLS
                     ELQEEYGDLVYSHIVSERGVIKRWGREGLNKSIPHSKTAYSMYVDIVEETLVRLEKAT
                     GENILERV"
     gene            8973..9410
                     /locus_tag="ACIZE9_000992"
     CDS             8973..9410
                     /locus_tag="ACIZE9_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092872.1"
                     /translation="MMSKTKKVTSAGSNGSGNPFGIKSGSGGFNIGQQMLKGKAGIKS
                     TGDKRKSVRVPVELYDEVVKDLSYGAKYSLMTEILALFLKEFETHGNSIVTDFGKLKT
                     RPVKISEEAFKVLKVIKFETDQSNTNIIASALTWYLDKRKGKA"
     gene            9730..10173
                     /locus_tag="ACIZE9_000993"
     CDS             9730..10173
                     /locus_tag="ACIZE9_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGC6092873.1"
                     /translation="MQILEDIKIYWKRIIGYTLVLLVVNLFLSMIALVFVNQRKDNVT
                     ELVTFISFFISGIFAPFFEETLMRGIIQNQLELKTNLSTRSIYIIVAILFSLSHLNLY
                     FIPYFMTSLILSFVYDNSDKRLIVPVTIHCFYNLIVILLSVVFYT"
     gene            10318..10641
                     /locus_tag="ACIZE9_000994"
     CDS             10318..10641
                     /locus_tag="ACIZE9_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092874.1"
                     /translation="MARSRIAKIEQTKKDKKISKNKTKFFKAEDVKRIAWSVKTFDED
                     RYVKVSMNGLFVQLGNFSNFKTIDELYPEIRNIVDSKGLIVAKRKSRNSGLAYCKNKG
                     IMIPA"
     gene            11059..14688
                     /locus_tag="ACIZE9_000995"
     CDS             11059..14688
                     /locus_tag="ACIZE9_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC6092875.1"
                     /translation="MKKLKLISIALFSLITMSTARQSIVSAEGTSTKAVVEESGDKKV
                     AIDDKVKNEAEKATVVQGADGLMYVVVDENDPEKLLEAESPLKNQQENTGAVEVGVDE
                     KRQEKADKANEKVKNFDDIDYNDISSLQSALNDPKFPFLSEDELNEKLQKTKNTFESE
                     ALMKKTRGYFSQRILELSNNLNDVPKRAKVSRHALVSNRASQVSETRINPPNGYPWVI
                     YLIRSNGYSYTENYAIRRTIDGKEAFCLQAGVQATNTYTGSTSGYLSNSQREMISSIL
                     SAYKELGGWANNDAGKQRWIATQMLVWENSNEKPKSITVTPNWKNGATKWKNDLVARA
                     NAIRVRTKWDSTSKTVDEGDKATFKVTNTYGDHNLHVKSVSGGGKATISNGTLTVDTT
                     GATGNKITVDMIKGSHPSDAHPTTVWSNGSYQKLVTGSFYISTSVTVNVKRKGTVEVL
                     KVDSETKKPLSGATFRFSYSGKTKDVTTDSNGKAKLTERLKAGTVVKVKEIKAPNGYQ
                     LDSSEFSITVKENQNVTTTRTNKKSTGSVEIEKIGDLDGLGLPNVVFTIYNSDNKVVK
                     DNLKTDSNGKIKVDELQFGKYYAVEKQGVTGYDPDGKKYNFEISQDTPFTKPAKVKVT
                     NIYEVSISEKVSDMNESQVLKNNWSADPNDYLQYDITTGNLKKSGERNVQSFIIEGFY
                     DNKNVDVSKSEVYVGSTNVTNSFDINNDTNNGKVIAKAKTSVLTNNDFYNKSYNLRIT
                     MKIKKSTLENTEKQKNLTIVKNSKVTVGSKISKSASSNDVETVLYSRKVTINHIDEKD
                     KHLLKQDIDYKYDGETYEYKPRTDLFDKDGNNYKSDVIHKGKIDGKDIVLNTPYHIPV
                     LSVNVDRIQIDTARAVKNGYLPTKIELSKKEEYEKELEKIVFKVKITDIDNNKVVYDE
                     NFKYKEFNSHMSLDLPTEYLTKNKKINYSVDILLVDNPDKNKFETETKDLRTIGYTSS
                     EKVLTNKDMTNNQVNYSAVVRTVKERENNNPVKEFNESINYKFTDSTKTKTGYGISVD
                     LEPTYRNEIGKQIDMKVYSYPMNELIDSKIDEIYQSGGKETEVKMDRLKNDGKVESGI
                     STQNLSFQFPHMNIERKTGNIYADSQRNDESIKYELIDGGRKLYVPIWCDLGNYSIAI
                     KSSNFGGNYISLDMNQNIDVYAYMYATIDSETKKDDELLLEPVYPESTLPDGWSKNEI
                     DWLNK"
     gene            14748..15110
                     /locus_tag="ACIZE9_000996"
     CDS             14748..15110
                     /locus_tag="ACIZE9_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092876.1"
                     /translation="MRVQSYGNSVFDVKREFQDSRRKTKKLIAYFILSAIVFYIVKFV
                     LELNSIVFTDMVHKMLNGEPINFNFDYMLEKAQSNQIVAFIVSIYYFIEKSIFSLKDF
                     FFEMLTKLTTFYNKISKN"
     gene            15124..15276
                     /locus_tag="ACIZE9_000997"
     CDS             15124..15276
                     /locus_tag="ACIZE9_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092877.1"
                     /translation="MLDQNTDRSWWMIGAVIVGAILIGTAKVAFPEVFNIVITFFKNM
                     IPTNLG"
     gene            15365..15766
                     /locus_tag="ACIZE9_000998"
     CDS             15365..15766
                     /locus_tag="ACIZE9_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092878.1"
                     /translation="MDGSDVMLRDMPKMILLMFVGFFLILVIAYYSLNGYTQDSSVKG
                     MQETLRTTAIANRDDSIRVEKGRFALIKSDFEKDFKEKFGKSKNLNNETADYKFDYLT
                     DGKDGIKAIKVKVESGSKEYQATCILNVAND"
     gene            15778..17193
                     /locus_tag="ACIZE9_000999"
     CDS             15778..17193
                     /locus_tag="ACIZE9_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase, T2SS/T4P/T4SS family"
                     /protein_id="HGC6092879.1"
                     /translation="MRVVEEKKISPKIEETPKSKINIASIIKKNGIKENSEAIEGNLD
                     FLTKLLEEDSGNYEPPIEDAKLNMIRDDLTRNYSQEVLQALTDDEIRRKLVQVVLKEH
                     GTFFKKDKEVAEYVVRECIGTGIIERIMTNDEITDVGWNGSQLSIETNSNKWLFDGDK
                     LNITQEYIERVISKYAVVNDRAFNSGNPIMDGMFKNVRISATHIDNSPDGSTFSMRVA
                     RPRLALNKENFEDFAPDYILELFEKMMKTKANICISGETGTGKTELQKLLLSFIDNHD
                     RMIMIEDVQETHAKELFPDKDIFSWITTPKKAISDLVKASLRNNPRWIIVSETRGSEA
                     YEMLQAVLSGHYVVTTLHAVNARAIPRRFVNMCASGFKINENAVEEDINRYFDFGVHI
                     KKTVVDGKVIRYLNEIVEFSASEPTTVFKQKFINGKFVIENGSLSEDFKEKMAEKFIT
                     FEFPEDQTNTEESLPEEEEVI"
     gene            17195..18025
                     /locus_tag="ACIZE9_001000"
     CDS             17195..18025
                     /locus_tag="ACIZE9_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092880.1"
                     /translation="MKVQAMTKRKGLMDVSELNAYQVAYGKPLDYRDYLNYVGLPCLF
                     MGGFSFALCYYWWIALICGVIGGVYGFKVIMPKSIKRSYELKSLQERNKFINNMTQIL
                     TDDSKTVTRALSIAKQRTKGELREDIQILESRLQGADKFQIAEAFREINNKYYSDVVF
                     TQYFEQLETAIYEGRNNSDTMKQIKSYHNDVKRKTEGFMKIKDGYLQDMKQMMFIVAV
                     FIGAITFAFGFSTFYEGFARSPIGWVFGSIYFLIMVSFMKSFFKHYFDDEIMSLGVSN
                     "
     gene            18025..18822
                     /locus_tag="ACIZE9_001001"
     CDS             18025..18822
                     /locus_tag="ACIZE9_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092881.1"
                     /translation="MKVKALKKKRKSSISPLKITKTEHKSFWIKLLGDVYYQKLREMN
                     NSNIAIIKWQKQRLKKSLIFILVGFLMYLFLGKEWYYLAGGIATSVGFYVWQAKSING
                     IYNQFRFERHLQFSKFTRLLIPYLKQKKDGGNLYGVFAKIVKRLDYDTDKKLLMKLMQ
                     EMTDQPNDIRPFTEYAEQTSGTDMSVLFMSTVYDIRQGSADLDVIEELDRLASEELMA
                     GIDSIIDYKSRRFVFFPTKIAMTSFILVVGFAVGVLFMNLKDINFGQ"
     gene            18840..19202
                     /locus_tag="ACIZE9_001002"
     CDS             18840..19202
                     /locus_tag="ACIZE9_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4320 family protein"
                     /protein_id="HGC6092882.1"
                     /translation="MQEQSVMEIIKWFIGLMMIMAMVSIGLFCVQLQDINTFKQQVNY
                     QIERKGGLTTEAVEAIDKYSATNYDRRFTIESDKLNQKVSYGEEIDYTIKATIPIQIL
                     PLPDVTLSFNGNSVSQIR"
     gene            19216..19362
                     /locus_tag="ACIZE9_001003"
     CDS             19216..19362
                     /locus_tag="ACIZE9_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092883.1"
                     /translation="MQENNVSRIIYLIGGLIILSLAIAGLVEHWPEIKLLIRNFYDNK
                     MIKM"
     gene            19374..19595
                     /locus_tag="ACIZE9_001004"
     CDS             19374..19595
                     /locus_tag="ACIZE9_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092884.1"
                     /translation="MEAIQENRKDNQETSEKNKKKRKKKVDKFTEMTDKIIEKKGLKP
                     KDFDRQAIKEARQKLYDDFVKENISQLLD"
     gene            19614..19889
                     /locus_tag="ACIZE9_001005"
     CDS             19614..19889
                     /locus_tag="ACIZE9_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HGC6092885.1"
                     /translation="MKNLVISKFAMLPRMDFFDNVSKFMSNMTSKLQGISLSVIIFCI
                     VVTGLMFLFGEGPSRTAKKWLTYIVIGAIIIFGASTIGQTIKSVGGF"
     gene            19998..21824
                     /locus_tag="ACIZE9_001006"
     CDS             19998..21824
                     /locus_tag="ACIZE9_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092886.1"
                     /translation="MNQRFEYNFEDVEPKLLKKGKGLKKKNKYTLKQAEALVGWIQHN
                     WSDKTTITLICSDTEEGTKYAFDGIEITPFSIGGQEKLLFPDIEGQILQAPDSMISDP
                     NKLILDINDQYKHEPDVAEPTKESKSKLNLKLPSVVLPFAKKKNKLMNELIEPEETDI
                     YEEELEEQEEIEELVVSSEETEEVEEIETVSENEEETEEIFDFEDEEEVENVQKGDLS
                     TSSQNGLEAVNDPQVPPYISSQTPNYSPQYQAPNVLQPLRKHETVQLVTLKEYCDLGE
                     EIETSISQMVEKLKPESLFKFIGIPSTGLTNTRIDEYRSNHAMLRLAEVKFENLREHY
                     SRQIISFKAEALDRLRTAVDIAWKKPYDLDVKKNKAEELSKMEAEAEAKLNEFVKRQE
                     NNVNDKIKKFEIEQEIDLKNFIARQEADKAVFIATEKDRTQNLIDSKAESINADLLET
                     KDKFIDEEMYKMKIEMNKNLFDGKQKIKSELATELAKANDNVWENALKFIQEIQDEIE
                     AKTPIWAAEIKEFNSLEEQEHERMKQTKELQLKEESIEIKRLEAEMNLKRMEELDHEN
                     KMLKIKLETALSKNELLAMEQDTKQVVNGSNRVGALNLFSKR"
     gene            21837..22553
                     /locus_tag="ACIZE9_001007"
     CDS             21837..22553
                     /locus_tag="ACIZE9_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092887.1"
                     /translation="MSVFNNKVMLGNCYVNHIGFYDGGTYRVLFLRLSVFSYSKDGKG
                     HYENINAQISCPLDRNGETTTTSSHPKALMNKFIFEKLDRNLVEGMKISIHGNIRGTE
                     QVLLNSGWKNFGQLSPLEKEEYQKIPKNELVTRNQTYIYIEEVSMPEKEEFRKSQSKV
                     TKEDVEVAEPNQADEILSDDTDPVNDEGEVIEVFEAEIIEEEEEIKSFDKRMYREKPK
                     GYVNFEDMYYDEYSNEPPIN"
     gene            22566..25424
                     /locus_tag="ACIZE9_001008"
     CDS             22566..25424
                     /locus_tag="ACIZE9_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HGC6092888.1"
                     /translation="MKLVQNNEVKEIKNGFVKNSNKILGKLKKVGSFKKNKYHTGKIE
                     GEDLPKSLQDKLNVPLVFIGVFLGSIVFLAITYLLNFLKALLVAIGQSESGLLGVEFD
                     PKFSLAYLKPLGDTKQYFMCAVVAVIGVAYLIYGKLNHESEKNLVYGQKGDSRLSTIK
                     EIKRDYHEIPEKTEVYDGIGGVPISHYQDKYYIDRDTVNTVVLGASRSGKGETFVVPL
                     LDNLSRAKIQSNMVVNDPKGELFSASKETLEKRGYRVLVLNIDDPLESMSFNPLQLVI
                     DSWANKDYHEASKRANTLTSMLFASGMGTDNEFFYKSAKSAVNAIILTIVEHCFNNDC
                     IEKITMYNVAQMLNELGSLFYTDPKTGKEKNALDEYFNTLPQGNQAKIQYGSTSFAGD
                     KAKGSILSTASQGIEMFTSDLFGKLTSKMSIDLKEIGFPKSIQFKVNTNLVGKRISIS
                     FLRKENDVIRLIKKYRVKVKALGLCVLNFNEYLQDGDMLDIRYEEEKSRAWYRIEFPK
                     KQANSHDTSLVTKKFKSGKNYSDLEISTLRLKYTDQPTAVFMVIPDYDPSNHVLASIF
                     ISQLYTELASNCKQTPDKKCFRRVHFLLDEFGNMPAIDNMDGIMTVCLGRNMLFDLVI
                     QSYSQLETRYDKAFKTIKENCQNHILIMSNDEETIEEISKKCGHKTTINRSASSKHLD
                     TDSSVTSSAEQERVITVERASQLIEGEQIILRNLHRQDTKRNKIRPFPIFNTKETNMP
                     YRYQFLAEDFDTQRDINEIDIACEHINLSLQDNQIPYARFIKDLKTRLEYSIINNIPI
                     SEEDYQDYLNLSGSQQTINEEELLKLVNTEVKSQDMEGQVLSEQEMKINIYLKESQKE
                     AIELVKVINGRLADENSADMVIKTINSQILDTPFIQSLINDSIAIHNVQESKDQIMIL
                     EQQLANAYELAVFKTKNSILKNKIIKLKNAMTKLAKAI"
     gene            25442..28111
                     /locus_tag="ACIZE9_001009"
     CDS             25442..28111
                     /locus_tag="ACIZE9_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HGC6092889.1"
                     /translation="MTESINWRKLNVQWLKYKWPIIVSLIIILFMAYPQRVFALPWIT
                     DNKEVLKFLTKYQDYLQFTKGGFGSIVVQSLSWGLIRGAYFVCKSAENLVPQSLSLFS
                     FVESSSLGAVYQSVLNTVVVGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALIL
                     LMPTMISSGIQFAKTFYKDSTTITKADGGVAWSLIEDGVTDLVYINKNDAYDRLGKDG
                     VQKNALKEKNFFSYDFSEVITVDTAKDLEDDNKKAEYLQSRLTPDGEGNMQAVKIDDG
                     WMSMFSDSFKGGYYRFTKNTFALTLGLLSLAVAYVFSIFIIVTAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFVSYLGTGGGSSVNPFIKAVA
                     YVCAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATK
                     PFKSMREMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGTNTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIGV
                     RENLQSSSTSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQS
                     STSSQGFKTVDVRENVQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIREN
                     DKGSKPRRRFTYEDNELFRDTLNDPNPLFDNLN"
     gene            28159..28470
                     /locus_tag="ACIZE9_001010"
     CDS             28159..28470
                     /locus_tag="ACIZE9_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5592 family protein"
                     /protein_id="HGC6092890.1"
                     /translation="MMYRNPKNIKQEIKLFFFYLVDLGIVAGSVMASVYFAKLMPISP
                     MMKFALYLLAFVVGVWMCVRTPNHPKERNILMLYYLFKMDRNRYHEVEFKRNSRGKIE
                     L"
     gene            28467..29084
                     /locus_tag="ACIZE9_001011"
     CDS             28467..29084
                     /locus_tag="ACIZE9_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092891.1"
                     /translation="MIVAESNENKLSGVFDKFLELVIPKDKDMCELLPYKKILKDGTL
                     VTNDNKYQAFFKVKTTDLTSISEDGFMRMVNKLTYLNRVYLEPYKIYSLTYPTETVNQ
                     AIYWKHRIQEAKRSLLSNNDPNLETYLKWNLKLAYDNYERVDLVSTLPELMFVICVYG
                     KTQKEVKNHADVMKQAGGRELDLQRITEGDLINVITKLMNPNTSL"
     gene            29100..29567
                     /locus_tag="ACIZE9_001012"
     CDS             29100..29567
                     /locus_tag="ACIZE9_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092892.1"
                     /translation="MLKHCRKGFCKVIKGKNAADLIFEWKESNLINVRGKNGSGKTER
                     VMASIDNSRPRSRALVITDEKNHYKGIRTIEKKYLTNNDLKVVDDILNIYPDFNLVVF
                     DETIPVTEIKGFYQSFSNLANKYEEVLFVWITEEDSNSKSAFFSEKNAFLHSI"
     gene            29583..31538
                     /locus_tag="ACIZE9_001013"
     CDS             29583..31538
                     /locus_tag="ACIZE9_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion system protein"
                     /protein_id="HGC6092893.1"
                     /translation="MIVSKKLARNLVSEGYDLRLVEKYQPSGGIKFDERYISTGDGYV
                     TSIAVIEFAEDVNSRWLTDIMAIPNTIATFDVCTADKEDLLHKINTSIGELDYRSTNE
                     NRTTDKTDALLDKYNLEDFAQEITKRGEVVKTVHARIFVYSDSLEELEKRISEIRKDL
                     ASVNHKAIVPQFRMKDEWMSLFQDGMEQESKLFAKKGLTVPAKNIGGGIPFHHKSLKD
                     PRGFYLGTTSTGGAFIFDPFYSTKQRRSFNGFILGKMGFGKSTLIKQLQEGLQAKNCF
                     IRGFDKSGEFEGMVKKAGGVYVDLGGGDMVVNPLQIYATVMKKDQFGNDVVDESKSFQ
                     NHITKCSNQIRFLEPEIDTATVREYTLMLQDFYIHYGILPKEWREARDDNERNQLNTN
                     ICNLPNDSYPIYGEFLKFIENQQFKIKNATPERVRSIELIKLIVTDMCTTYPQIFNGV
                     TTMPNFDTTKIVYYNIDSISKMSAPVFHCQLFTALTTIWNSALQNGKIQKENFKKYGS
                     DYYKYAQDFMVLIDECHNVINSNNKYACEYVLSFEREMRKMRAGVYFATQTPEEIIPK
                     DSGSEVADVIRNIFNLCTFKCFFNLDSALLEDIKKVLGNTITDTEIMLLPELEVGQAV
                     VQTSSEDTYMINFDPYPEQIERFDGGQ"
     gene            31560..32696
                     /locus_tag="ACIZE9_001014"
     CDS             31560..32696
                     /locus_tag="ACIZE9_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HGC6092894.1"
                     /translation="MEQNKNNNVASTLARQGMKQVSKKIGLALKIKIGVVIGLITLVG
                     LLVIGSLATLQGTQTATNTGGAEVIGGNKPLSPEVQKWQKTVEKYAEKYGIKELVPYA
                     LAIMQCESGGKLPDLMQSSESAGLPVNTLQYEESIDQGLKHLSNVYNIAKSYGMESNY
                     DGIVQAYNYGIAYMHYLGKNKKTHTIETAEAYSKNVVAPSLGNTTGQTYSYVNEVSIK
                     YGKTYLYLNGGNFYYAELVKQYIGGGSGNPANPSEFWGKMKTEMEKYQGWPYVWGGKN
                     PTTGFDCSGLTAYLYQFSAGITIDSYTVTQYEATEAVSIKEAKAGDLIFFRGTYGAPD
                     FISHVGIYVNETTMYDSNSSGIGYHNWQDSYWQSHSPEIRRVKK"
     gene            32711..33361
                     /locus_tag="ACIZE9_001015"
     CDS             32711..33361
                     /locus_tag="ACIZE9_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGC6092895.1"
                     /translation="MIKRKNDNKWKYICGVLIIILVLGGLLSQLHTSNIQAKNKKLDQ
                     EVTQLEEQNSKLSKNISDLNANVEANLTNDDGSELNKQIAEVAKKFVELYPVYDIEKV
                     EEKKADLEKIATPSVADSIVPDDMITTSKKTLESKSTTQKGEAYSSDPTFKSKYKDSK
                     LYTNYVNANTINYFAEVNYKTESSSGDTENTVYMLFEVTNKDGQVLVDNYEIKYLK"
     gene            33375..34271
                     /locus_tag="ACIZE9_001016"
     CDS             33375..34271
                     /locus_tag="ACIZE9_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092896.1"
                     /translation="MNKKYSIHNKKEPNKKNKAQIDKVYKKTKGVKLYLGAILGFLAI
                     GMIIVFSPYVMGKSYDFETVKMSSAQNVTSSLNMYVDDMEINREAGLFKLVLRYQDDT
                     GTKSLSNIKSDYKLNFITNKNNEDVKTKVVKLSDEYTVIYYQNLPKDFGVISVTVNPR
                     YIYPELEPSNDLKEKEIKFYAVDKDIKSNAKLEVESTSDLQKDNFKYQIKAIENSIKD
                     EKKSIEKMNLANKVVQKDIDKANQNLEFQTLDEQTDTKNEISSMQTTIENNKSSIEES
                     ENKIKQFEEKIKQLEKSASRFE"
     gene            34307..34537
                     /locus_tag="ACIZE9_001017"
     CDS             34307..34537
                     /locus_tag="ACIZE9_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092897.1"
                     /translation="MCNSIVTIQEKAEEELMRIEAEYKEKRKAIKRKKNAELKKYKEE
                     QALKLGMMLCKYYDCYDINEVLKKANLNQFCE"
     gene            34888..35184
                     /locus_tag="ACIZE9_001018"
     CDS             34888..35184
                     /locus_tag="ACIZE9_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092898.1"
                     /translation="MDVSIRGIDPQYVKEIDKKVNKIQERTGKKFSRNDYFLAIIRQD
                     SEIDLIDYKKSEFDLVVEKLLLSNEQMVESISELTSVYERLFNFLISERSDLNK"
     gene            35181..35648
                     /locus_tag="ACIZE9_001019"
     CDS             35181..35648
                     /locus_tag="ACIZE9_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092899.1"
                     /translation="MNYPYFKVSATEDVKEKFNKCFEVNKSVFQTKSNMFRYVVSNLP
                     MLTKANQNFRDPEKEELAKNLEEAKLKISELETIIELQKQQLENFNKKEDSTHKDYSE
                     QLNSIEESVYKLLINSGLASKELEEERAEPEQESSRLGEGTMFSSPSLRFTTD"
     gene            35730..37250
                     /gene="mobP2"
                     /locus_tag="ACIZE9_001020"
     CDS             35730..37250
                     /gene="mobP2"
                     /locus_tag="ACIZE9_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HGC6092900.1"
                     /translation="MTEHIFNRKSASIILKAKFETGKSKKNNHMVELQKFVDYISRQE
                     AIRQDKLDHDYSEDELNELARIEKALEKIEQETDQPVIKDLREMDKYIDYMTRKKAIL
                     ENVDNEIVNGAFSNTKRYITKKDISKIKESVIEAKNNGSVMFQDVISFDNDFLVREGY
                     YNPETNELNENVLYEATKSMMGKMQEKEELVDPFWFATIHRNTEHIHIHVTAMERKNT
                     REIMEYDGVLQARGKRKQSTLDDMIFKFGSKILDRTNEFEKISKLRKEVPLELKQSVK
                     DSLIQLYVENNSRYDKELVKYLKELKKEIPSTTRGYNELPEETKEKIDEVTNYMTKDN
                     PKRKEYDRMTKEIDELYQTTYGKRYNPQEYYLNRKKDFNARMGNAVVGQIKLLKQSEE
                     KNLKSNELKNLLDGKKLNVKFDREKPEFKTKYAKQSYDDFQKRLEERQLAREKNEVHF
                     KKISEKFKDKKLIRKIDRVINDDLNMYRAKNDYEVAQRMIEQEKMRQAREFEIGMN"
     gene            37272..37601
                     /locus_tag="ACIZE9_001021"
     CDS             37272..37601
                     /locus_tag="ACIZE9_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092901.1"
                     /translation="MKNFDIVCSNTKNIYLRELLNSDSETIEDVKKIIVLFEKENMEL
                     ENWGLFEIPISGNYCFYNWKTEDDVAFANYFFDKNYFSPLYIDKHSNEQVASSIKEAI
                     KLERVRK"
     gene            37603..37866
                     /locus_tag="ACIZE9_001022"
     CDS             37603..37866
                     /locus_tag="ACIZE9_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092902.1"
                     /translation="MIDFRTVMDKLSNGDFRVLIELYLNVTSTVKEFLYSNPKTALVL
                     VAVLIVFAVISFIKKMIPLLIIGAVLILGLYFPEVLDQIKNIF"
     gene            38041..38907
                     /locus_tag="ACIZE9_001023"
     CDS             38041..38907
                     /locus_tag="ACIZE9_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092903.1"
                     /translation="MKKLRVIATIPMIFSFALLLSACGKEEAGAKSNEAHNISFIDSA
                     EQKDSRCWLVVETSSKNKTPIDKNEYVKAVIQTKDGKAKVFKTDMEQLTLEKVSKMSD
                     EEIIEQALNADKQKFNDKKKSDIDSYNATLDSVKTELENEEKQEFQNDQKIADFQDSI
                     PKIQADIEEIDGVQYSEPEWKMVSATIKMDNENKSPSMETVKLSYKYLDSPIWNLNSF
                     GEVSSEGELSYESTSMDLKLSIPVATTKVLDNFYSGYSNDELDQLLLTKVASKDNKVQ
                     LDSKGKNVSIVE"
     gene            39062..40888
                     /locus_tag="ACIZE9_001024"
     CDS             39062..40888
                     /locus_tag="ACIZE9_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HGC6092904.1"
                     /translation="MAYKKGNWKPKTKEQKQKELDDLIKASNSKIEQYQSNPEDMIEF
                     AKFMSKIHNYSPLNLSLIDEGFEGAIAVASYDGWKKLGFQVKAKEKGIGIYAHAPVTV
                     FIDENGEEKTLKEATNEQKEKIKNGELRSKKIKHFKKGYVFDISQTNATEADLPKIFP
                     NRVWNFNIDGELSVSQLEKGVNHLAESMNISIKDMNESGRGEMGSARGEYIQYVDGRE
                     EIVLNSRNSRTQNLTTSIHELAHKKLHNKNEHGSSYSTPIKEFQAEMTSFIVCHNYGI
                     DTSDFTIPYIANWTKNNEKIDPKNFRQIMQEVRETSIDFISTIDKKVLEEQQTAFNAL
                     KNSFVPNENKEQIQQKSDLEFHNFYDSTINDPDRTIHGSYLEAMVDYYRGKYGENSIE
                     LTHSNYDVTAKIGENYVTYYSDTKQFDVCDVYGVVFENPSENKHDRLLLDRSPENCDY
                     VEKFVVESLKACENHELKNDTLKLSEPLRSVVINEAVYNLSENANNYYNEKCWQEEIE
                     NQTNINDVKELNSCMTAEDFYESHKQEIENTITDFESVSGTNLRDTIDNESYKEVASV
                     VAYKLVATKVKYEMDEGTFKIPENSNLEKPTVKTAERSFEME"
     gene            40896..41969
                     /locus_tag="ACIZE9_001025"
     CDS             40896..41969
                     /locus_tag="ACIZE9_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092905.1"
                     /translation="MSNEQNYETGGTYRLFHGSMNKFDEFSLDHKGLNGTANGFGVYL
                     TPNKEMATMYAEQGSNGNNGFVYEVNVELEKPISMNERTITDEELSKVIDKLQESNDI
                     LNDYNDVSYYGEKVVKREVIASLSENENDVDLINDIGNTIGDHEATAKAFYDVGKYTH
                     IIAEEQLRQKDVVIVVLQPDKVKIETIHDLNEERNSLESSEDMTDKFVGHKVSEVPIR
                     EVVIKDFEQELETTNYYDKQAWQERIEYLENMEEPVSRLALDSDINEFYDSHKEEIET
                     KLTNLSEKLEIDKEELLGFPVDTSSTEYKKATSIMAYNGAMREIYNEIENDTFEIPPV
                     SEEMENKILKLTNFENTTKFEME"
     gene            41978..42238
                     /locus_tag="ACIZE9_001026"
     CDS             41978..42238
                     /locus_tag="ACIZE9_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092906.1"
                     /translation="MIEQENRNFLETQGEYRQINNSHFVICEDVQIAFKMALKYGKSI
                     RKKIIREKKSKKIGFWELSLRDGLNFIFCTEDYYEKYKCTLS"
     gene            42275..43279
                     /locus_tag="ACIZE9_001027"
     CDS             42275..43279
                     /locus_tag="ACIZE9_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3991 domain-containing protein"
                     /protein_id="HGC6092907.1"
                     /translation="MDLKKAKKVSIVDFCKQNGIGLKQDSREYYRLEDHDSCVISDRK
                     NLFKWNSKDLGGDIFDFIKAYYDCSFKEAKQKLEDSDYEVHSFNTKVKKAPYQYQKEN
                     EVPVSVAKSYLVNERRIDTALVEDFLSKGLIKQDKKGNVLFLWKKDQEIVGCTEQGTR
                     KFFHEGKQKDVTWKKIQENSKEYSGFNVTFGQPDKMYFFESEIDLMSYITQKPEKAEN
                     ATFVSMNGLKVGNVLYGVTEHYNKFKSLPSETVLCVDNDKAGRTFIETEFKEKGIGRE
                     GIGISEVKVDVPLREGFDWNDNLTRGKEAFKRFKLEDVSKIVNFTHKLSLNTPVYEME
                     "
     gene            43304..43660
                     /locus_tag="ACIZE9_001028"
     CDS             43304..43660
                     /locus_tag="ACIZE9_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092908.1"
                     /translation="MNDTIAILSDSLIDLDKTSTDYMIIEEQLKNKNPEFDIQEKSLR
                     IELPKFKQKKLITILFEIIERYGLTYYQIWTDKKDGQYTKGVSIEAVREDDQVSIKAV
                     QPLMGYNEELLNCLNV"
     gene            43822..44013
                     /locus_tag="ACIZE9_001029"
     CDS             43822..44013
                     /locus_tag="ACIZE9_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092909.1"
                     /translation="MEQTRMFWSDRMQDHLDCIYKTREQLNKLDTVRYYFTYFSENDE
                     QRWDIFHDGNYEEFFYTES"
     gene            44122..44340
                     /locus_tag="ACIZE9_001030"
     CDS             44122..44340
                     /locus_tag="ACIZE9_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092910.1"
                     /translation="MVNKKETFKVGMEVQGVVIGSGELIEGEVISLLANVAVVKAIGK
                     APVVMKKCSMMCLDGLNNPITQRFENVI"
     gene            44377..44694
                     /locus_tag="ACIZE9_001031"
     CDS             44377..44694
                     /locus_tag="ACIZE9_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092911.1"
                     /translation="MKDYASRKFIHLEPMKELVINGNEYNDYKSLFVKEQPKGGIRMK
                     NLPDFRFIEVNNLGIIEDYLDKLDEAIKQSIEKNGEDHILTVVLKDLKDRLEAEAEYF
                     NKD"
     gene            44705..44902
                     /locus_tag="ACIZE9_001032"
     CDS             44705..44902
                     /locus_tag="ACIZE9_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092912.1"
                     /translation="MRAMTEAVKELKKMYPDVLNMTVDDFHEALKNAESEEERTFYLT
                     LSSFVTRVDQKKVINQKDFKI"
     gene            44899..45867
                     /locus_tag="ACIZE9_001033"
     CDS             44899..45867
                     /locus_tag="ACIZE9_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HGC6092913.1"
                     /translation="MSLENEKPYYVVVGGVNGAGKSTIYQVQNLKRKELDTDRINADE
                     ILRSFGGNWKKQADINKSMREVLREIKGHFKEGKSFHHETTFGGNPYPDKMRLLKAKK
                     LGYESFLIYIGLDSPERAIERVKIRVAKGGHGVPEDLIRKRYEFSLRNLAELEKYFDN
                     VSIYDNSDEFSYIYVKENHTVVANNTQEYAWVPKAIQEKNAETPISKQIMMDISQEEM
                     NPKETLERIYSASDDFISDRFSKEAQVDDFYRNHKNEIKERILSISFSTGVSQDELVG
                     QDKRRNSCKLAYINSVGELLVKTDSELLSMELNRDRNIQKTDFEVE"
     gene            46111..47283
                     /locus_tag="ACIZE9_001034"
     CDS             46111..47283
                     /locus_tag="ACIZE9_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092914.1"
                     /translation="MTKKIEVYVDGSQEERDSFFGFFWKNSREYVKALNMVYKQLMFE
                     ELIENSIKELDHEYIKRELSLEERIDNLLSNEVIDQKKLDKTKRELSKLRIAKNKEAR
                     DVLTQAIGLKSQTRIRDIAKKLDFDYSDFIDSAKMKASKDFSNDFVGIVTGQRTPRIY
                     RNKNKYGLLPFRGRDIKIHKADKFYISLPKGFRFKVNLGRKPRKARDSALTLERIMDG
                     QYKLNQSNLIFEGKNLFLNLTISFEKDYHKLDFKEGAELTIKFTDLCSGKCLVNNQSV
                     IDFGDSKYISNFKNKIKAMKSREQSRGVFSKGGHGRKRKLDQDRWEAIKKRESNFVKT
                     YNNQCSAKIIQTAIRNKTQIICISEPDKNYGEWAYYQLKEQIINKGKRYGIEVKSE"
     gene            complement(47843..48220)
                     /locus_tag="ACIZE9_001035"
     CDS             complement(47843..48220)
                     /locus_tag="ACIZE9_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGC6092915.1"
                     /translation="MKKSYPVIFSAEENGYSVVFPDFAGATQGDNFEEAMSNAKEFLD
                     GILAYYIDEDISVPSPTDIHQLNNLGNNKIVSLIQSDPSPFIQKKTVRKNVTVPEWLV
                     ARGEKDKINFSKVLTDALLKIYE"
     gene            complement(48266..48454)
                     /locus_tag="ACIZE9_001036"
     CDS             complement(48266..48454)
                     /locus_tag="ACIZE9_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGC6092916.1"
                     /translation="MPLTGKKMLKLAKKNGWKVVRITGSHHIVAKEGFPPVPIPVHSN
                     QDLKKGTEQKLLKDLGLK"
     gene            48646..49167
                     /locus_tag="ACIZE9_001037"
     CDS             48646..49167
                     /locus_tag="ACIZE9_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6092917.1"
                     /translation="MNKKQDQEYYIEKLEKENLELKERIRYYETKFCKRGDCMKPNPV
                     ETGKRIKSIRSNFGMTMEQFADLIGNAQKGNINNWERGFSLPNKERLIKIAELSNKTI
                     DWIKWGTLEEYITSYLIGIGYELYIKDFPEIPHKVFKDIQEKYSDTFSLDKDYELLDS
                     IIKNIFTKYYSNG"
     gene            49362..50258
                     /locus_tag="ACIZE9_001038"
     CDS             49362..50258
                     /locus_tag="ACIZE9_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092918.1"
                     /translation="MEINLFEAGNRIKQIREKHGYTMADLGKLVDANSPSTINNWEKG
                     NNLPNRKRLEKIALLGGTSVEWIKYGDFSDYVYRLTQNIEEKILKEYGETTLNNYREA
                     LLDELTIEKITYEEDTKILAAAEKINTQNIFQEVKYMYSPDEDYRNIEVKPDLGLTDD
                     NKNIKMIGQRIRKIRKKENITLEEFGKLFSPTADKAVISNWENGKNLPNSERIKKIAE
                     IGGVSELYLMTGVDSSVAESMYFLSEVALDALERLSIEEVNRIIESFAGYLNVISKID
                     DPDKREISLNAICQLSLLDKMG"
     gene            50307..50681
                     /locus_tag="ACIZE9_001039"
                     /pseudo
     CDS             50307..50681
                     /locus_tag="ACIZE9_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353455.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            50961..>51481
                     /locus_tag="ACIZE9_001040"
     CDS             50961..>51481
                     /locus_tag="ACIZE9_001040"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6092919.1"
                     /translation="MTQTDFAELMGLSRSYIGDLENNRSNPSIKTLEAIARALDVPIV
                     ALINDSSTDNIVEPYESLTAENILLKQENEELKYEVESLRKRLYEIQQVVNQGAEKMI
                     PNLKDVSKRIKYIRKKLGMTMEQFGSHLSNSPKSTIATWESGRNIPSQKKLQLIAIVG
                     ETTTDWIKWGTLE"
BASE COUNT        19950 a         6372 c         9815 g        15344 t
ORIGIN      
        1 taaaaaacga gtatcaaatt cagttgcaat ttgatactca tttaggttta cattttcact
       61 ttttgtactc caaaactgaa ctacttaaat gaaaatgtct ttcctttttt tttgactaca
      121 agtagcctga aaatgaaatt tcaaaagact acaagtagtc ttttgtggca aaaataaaga
      181 gccaacgaaa gctaccaaca atcgttgact cgtaagactg ttcgtagtaa gaaaaatctt
      241 tggcaatcca cgaagtcttt atttcataat ttatataaat gattatacag tcactttcct
      301 gaatttgcaa gtaaaaaagc taagaaatat tgtttaagcg tttccttaaa agaatcttta
      361 aataaatttt tttccaattg aaaacatgac tacaagtaga ctatttcttt tattccaagt
      421 tgactacaag tagtcaaggt gatataatat atatatcaag aaaggagaaa caaaaatgta
      481 taacgtagga gatcaaatag atgagatcgt aaaaataggt aatgttaaac ttgttaaaag
      541 taagtactat atttcagaaa ctgaaataat ttttaatact gaatcaggat gtattctaat
      601 ttggaaactg ccttttccca aagacgaaac aacactgaaa aaaataaata ctttaaaaat
      661 cagatattgc attcatgaaa ttattgataa aaatacttat gttataaatc aagtaaaagt
      721 gatggggtaa aaatctttta aaaaaactct tgttaaaagt aattctatta gcttataatg
      781 ttggtattag ttctgaagcc aaaggaacac taaaaaattc tagtagaaaa gttagttaca
      841 gactctctac tatgtatgaa tgtaacgaaa aaaatagcga aaaagataat taaataagac
      901 taccaatctt atttaatgga acttctgtag taagaaaagc gatttggcaa tccacgaagt
      961 ccaccaagat gagctaccaa ctcattttaa tttttgcacg tttaaagttt agcatttaag
     1021 tgcttactct aaagacatag tgtaatttta ggactcctta ttacggaatc taaagttacc
     1081 ctatgtcttt tttgctattc aaaattgata gcaaggagaa agtgcaatgt tgaatagttg
     1141 cgagtatgcg gacgttttag ctaaaattct taaaaatgga attaaacagt ttaatagcaa
     1201 aaatctagtt gcttttaaaa agaatagcaa taagattggt gctattgccg gatttacttc
     1261 taaaacaaac atgataaaga ctaaaggtct tatatatcgt tctattgatc gtgtcttgga
     1321 agattcagat gtattaacac actggactcc taacgtgtat tcatggcttg gtggcggtga
     1381 aaacaaaaca atttttggtc acaaagaagc taacttaatt cagattaata cttttgtagc
     1441 agatattgac tatccagtag gagaaaagaa aacggatttg aatttactag ttctttatct
     1501 attggaagaa gggttattgc ctacactgat tgtagatacg ccaaaaggtt atcattgcta
     1561 ttttctgatt caaaactata accaagaaac tgattcattt gataaggcaa gctatatttc
     1621 taattcaaat gattttaaat ctttgagagt tgctaaaaga atatcagaaa atatcagaaa
     1681 atctatccaa aatcgtttac cacaagtcga tatgggctgt aatcattttg gtatttttag
     1741 atttccaact aaaaaaaata ttgtacatta tgaacctaat ttcgtagata cgtttgaagg
     1801 gtatttgaaa tggtcaaaag actttgaaga aaaagaatat gctttaaaga ggtctaactt
     1861 gtcattatta gctcctaatt ctactggcaa gaaagggtct aaacgacaaa ttgatactaa
     1921 atggtacgac tttttaattc atacggatat tgctgaagga gatagaaata aaactatttt
     1981 taccttagcc ctggcatgta aatcaagtgg cttatctatt ggcgagtgta tggatcaatt
     2041 ggatcaactt caattcaata atgatttgtc ctattctgaa gttgagagaa caataagaag
     2101 tgcttatcgt ggcgattaca aaggtgctaa aagttcatat gtcaatgaaa ttatcgaaaa
     2161 ttatgctaca cctaccgagt ttgaaaaata ctcaataaat gtaaatagac aagctgttaa
     2221 acgtaaaggg aatcgtgtcg atccgtctaa ttgggtgaaa tttgctaaac ctagagaaga
     2281 acgaaaatat agtcattttg aagaaagtaa agctgattta ttagcttact tagaaagaaa
     2341 acaaagatca ttgaaaaaaa atgagttgtt tttaagtgtc tctatgggaa ctatatctga
     2401 agaaacacaa attcctgtat ctacgttaaa ggtgatttta aaagagctta gaacggcgaa
     2461 tacagtgata ttacgaacgt ctcgtggtcg gtatggatcg actaaaatag caacaagcaa
     2521 atttgtggaa gctaaaatat taaatacagt tattcagaat aaaaaagata aacaagtatt
     2581 tgtcttagaa ttattaggaa cagcaaatag ccacgtagaa acgattttaa gacgttatga
     2641 agacaaaaca gtaccgttcc atgcgaacat actgaaagaa agagaaaaga gcaaacatgc
     2701 gccaattaga ggagctaata caggttagag ttctatttat ttttttgatt tttaaatagc
     2761 taaattgcca attaacatat ctagtgtttc tgcccactcc tattcctgtt ttagcgtata
     2821 ctaatgatta gtagttagta ctctctttta tgtatggagt gtatagaact atttttactt
     2881 gtgtcttttc ccttaatcca cgtgtacgga atacagctta taactgcgta tgcagttatg
     2941 tttgaaggag gaagattttc tttggtaatt aagaaatatg tttactcaca cccgatcaat
     3001 gtatttatta tcggtaagct aggtttatct gttgaggtgt tttgtgagtt atatggattt
     3061 aaacaaggaa ctctatcgtc ttggattact agagagcgtg aggtagctga tttgcctatt
     3121 tcttttttgt atgctttgtc tctagcttca ggagggaata tgaatgaggt ttatgattgc
     3181 ttgtgtgagt atgaaaaaga gtataaagag tatttgaaaa tttcagcccc aaaacggaat
     3241 aaaaaatata ttgaagatta gagaaagaag aaaagaataa tttgtttttt tgactacaag
     3301 tagacagata gctactctgt tttttgatag tttgatattg gctgtttttt tgttagaatt
     3361 aatatatatc aggtaaataa aaaagggggc tattaatgaa tattgatggg atttataatg
     3421 aatcagattt taaaaaaggc atagtagata ttgatagaaa agagtattta tttcctgatg
     3481 aaataggttt atttaaaatt gtaggtgaaa ctgtctgtag gtattggggg aagaaaggaa
     3541 atataatttt acttgttgat acgattgagg gaagaaagtt aaaattttcg ttttggagta
     3601 atacaaaata ttgttgtgaa cctgtaccta aaagggaagt agatgtggct aaagaaagtg
     3661 tacgattttt acctgatcga tcaaaaataa ctttaatttg tgaacggaca agtaatgcta
     3721 aatttacaag aattagagat atactacttt cgactacaag tagtcagtca tagagtaaga
     3781 acttttggtt aaaaatcaat tgaagaaagt ggaggaagta tatggcagta gttatattag
     3841 cagaaaaacc agatcaagga gcaaaatttg cttcagcatt ggccggaaaa aaattatcga
     3901 aaaagagtgg gaagtatgaa tttaaaagtg aaatatttgg agatactatt gttacttggg
     3961 gaataggtca tttggtagga ttatcattac ctgaaaagta tgagtggcta ccgaataaag
     4021 ataaatggca tttagataat ttgccttttc tacctaaatt caatgaatta aagtatgaag
     4081 tctctaaagg aaaaaaccaa caattttcaa tagtgaagtc atgtttagaa aatgcagatg
     4141 agataataat tgctactgat ccggatagag aaggagaaaa tattgcttat aatattttca
     4201 aattatgcaa gcagtcgatt tttaataaac cgataaaaag attatggatt aattctttgg
     4261 ttcaaaaaga aattatcaaa ggatttaaaa atctgcgaaa ttctgaagaa acgatctctt
     4321 acttcaaaga agctaatgct agacaaattg ctgactatct agtagggatg aattatacag
     4381 agttgtattc attaaagttg caagaaaaag gtatatcggg tgtggtatca ctcggtcgag
     4441 ttcagacacc ggtaaacaca cttgtggttg aaaacgattt ggcaattaga aattttagac
     4501 cggaaaaata taaaacgatt gaatgtcata caaccgataa gcaaccaaaa gcaatattta
     4561 agaatagtct tgaatacttt aaattagaaa aatttgaaga agacactaaa aaattcggcc
     4621 ttgattccgc cagtactgga atcataaaaa aaattgaggt tagtaaaaag caaacagaac
     4681 cacaaaaatt gtttagcttg ggtggtattc aagaatacgc taataaaaaa tggaaatatt
     4741 ctgctaaaaa aacagataaa attatccaaa gtctatatga tcgtggatat ttatcttatc
     4801 caagaaccga tagtgaattg ataactacaa atgaatttga gtatttaaaa gcgaatttag
     4861 acgtgtataa gagtgtttta gggatcagta ttgatacacc ttgtttagag cctaaaaagc
     4921 ggtttgtaga taatgacaaa gtattagagc attatgcact aataccaaca atggatattc
     4981 ctgatatagc aaatctgaca ttagatgaaa aaaatattta tgagatcgtt actaggcgtg
     5041 cgtgtctaat gtttgcagaa ccttacaagt acgaaaatac aaaagttaca ttagatgtaa
     5101 acggcttaga atttaccaca agtggtaatg tacctatatc tttaggttgg aagcaagtag
     5161 atactaattt agatgaatct gatgataaag aggaaacatt acctaaattt catgaacaag
     5221 agacaataaa tatagatatt agatttattg ataaattaac taaggaacct aaaaggttga
     5281 ctgaaggtaa attattaggt aaaaccggta ttatggcgaa attagggcta ggaacgcccg
     5341 ctacacgttc taatattgta gacactcttc taaataggga atatattaag atagaaaaca
     5401 cgaatgttta tcctactcca aagggatatt tattatggga tttgacaaag aataaagacc
     5461 tattgattgg aaaaccagaa aatacagcga tatgggaaga atcacttggg aaaattgcgc
     5521 aaggtagcta tacacaggaa gcttttttaa gaaatatcta taactatatc aataagactg
     5581 tttcagattt gaaaaaagta gaatttactt cggattattt agaaaagact gtaaatcaaa
     5641 ataaatttga tataggtagt tatcaagtgg aagaaaagaa aaaagtttat tctattttaa
     5701 atattactag tggtgaacag ttcgtgatat ttaaaaatat atcaggaaaa gcaatcaata
     5761 aaaaagttct tcaagaacta ttactaaata atcgtacaga taaagtcctt tccggcttta
     5821 agtcaaaaga aggaaaagct tttaatgcaa gattactttt cgatccaaat gtgatgaaag
     5881 tggtaatgga gtttgaaaag aacagtccaa aaggcgataa aaagagcaaa cacgatacag
     5941 taaatggtta tgaaatagtt gaaaaagcaa aagtatttga aataaaagaa ttagcaacag
     6001 gtgaaagttt tattttctat aaaaataata gtgggaaaac tttaagttca aaaacagtca
     6061 aagaattgtt agaaaatggg aaaactaaag agaaagtaac gggttttata agtaaagaca
     6121 ataaaaaata tagtgcttat cttgtctttg ataataaaaa caaagttata aagaaagaat
     6181 tttaattctt agtggcggaa atcatttgtt tttccgctta tttttattca aaagtgccca
     6241 aaatataggt atactgaatt aaggataaat acaaaactag ttagaggaca gttgaaaaaa
     6301 tacaaacaaa ttagattgct attttgttaa attggaagta gaataatacc gttttgatat
     6361 gtatagtgtg ttttaccaat aaaattacat aaacgtgaat atatttttat gaattaaatg
     6421 taaaatgaga gcaattagtt ttaaaaaaga ttataggctg ttaatcttag catatataat
     6481 ccattggaaa gggggagatc caatgaatct aaagaataca aactcaaaca aatctacact
     6541 atatgtaatt tcagatgatt atataaataa gctgaaaaag gtggactatc gtgtccaaaa
     6601 caactatcga gaacaacgat tatattttaa atcaaacttg aaaatttcta acaaaaatga
     6661 agaaataaat tattatgtac cattggcttc agcaaaagaa aatcaacgtt ctttgactaa
     6721 taaatcagtg tttaagattt atggtgatcg agaagaaaag gactttttag gagtacttca
     6781 tataaataat atgattcctg tgccaaaaga ttgtgcaaaa gtatggacac ctaatagccc
     6841 aaatgttgat gagaagtata agatgttagt aatcaaacag gcaaaatatt tgaaattaca
     6901 tgagtctgaa ataaatgaat catgcgaatt actttataat tctaagttag gtaaacttga
     6961 tcctagttac tttaagaaaa atcgtaaaga agtaattact tatcaaaaaa taatgacgaa
     7021 tgtagaatca ttggaagctg ttagtatagc agaatcccaa agaaatattc atgtacaaac
     7081 tcaaagtata gatgtagagt aagataggct aaacctatct tattttatta ttctattgga
     7141 tattatgata cattgaattt taatcgaata tgtatttaaa tgttattata ctgtagaaga
     7201 taaaacttaa aggatgattt ctatggcgag accgagaaaa tacaatacag aagaagaaag
     7261 aaaagaagca atgaaaaagg ctaggaaaaa atgggttgaa aaaaatcagg aaactattgc
     7321 ctatataaga gccaaatcat ttgctaaaaa attcattgaa atgtctgaag atgaagatat
     7381 tgaattgttg gaaaaatggt tagaagatcg gaaaaataac ggtcaaaatg atgaataata
     7441 accattgact acaagtagtc aatggtgtag aatggtttta gggatagaaa tatccctttt
     7501 ctaaaagtct aatgactaca agtagtcgat agagggatcg ggaataaaaa cagacgatta
     7561 tggcctaaag aaaggaggaa tatgaatatt ttgaggaacg atttattaaa tgagcgttga
     7621 taaatttcac taaatatttt cttaatatct atgtattgtt caagcgtaga aaaaaatatt
     7681 gaaattatta caaaaccgct cataatggaa aataacgaat tatattaatg aatcgttcac
     7741 ttttgacctt ttttactaga tttttttgta ggacttttag agaatttttt tgttatctga
     7801 ttataaggag gagctaaagt tgatagagaa tagagtactg gggttcgtag agtgtaaaga
     7861 taatttagac gatactttag aagtccttga aagtattata tttaacacca aagttctgga
     7921 tttgaaagca attaatggtg atatgacaac acatatcata ttagatgaaa ttagcgcaaa
     7981 agagattggc gaaactttaa tagcatgggc taataaagag ctgtaaaaga taattttaaa
     8041 ataaagtggc caattgacta caagtagtct gtatagtata ataaattatc aaaagtgagg
     8101 tatacatgat gaaatcaaat tttttgggat atgtaattgc aatcaacatg tttaaagggg
     8161 gagttggtaa gtcaactctt actcagctaa tggctgatat tctatcggct agaggcttta
     8221 aagttttagt tattgatgtt gatccacaag gaacagtaac taaaaagttt caaagacaat
     8281 atgatttaaa agttgttggg aaaatgacat tgtttgaagc agtaattaat atgtctttct
     8341 tagactgcat ttctcctgtt aaagaaaact tagatattgt gcttggttca gaacaaatgt
     8401 caaggtttac caaagtatta agagatatgt ggagaagtac tggttttact gatgaaggtg
     8461 aagaagtctt ttggaatttg tttaattata tgatcggtaa tgataattta agagatcaat
     8521 atgattttat tttgtttgac actattccta cagtttcaga atttacagat aacgtttacg
     8581 tggcgagtga ttttttagta attcccacgc aaactgagca agattctata gacaacttgc
     8641 atagtacggt tactaattat caaactgctg taaaagaagt aaacggagat ttagaaattt
     8701 taggtattgt tccatatcta gtggatacta aattaaaaac aggattagaa cttttatcag
     8761 aacttcaaga agaatatgga gacttagttt attctcatat tgtttcagaa cgaggcgtaa
     8821 ttaaacgttg gggtagagaa ggactaaata aatctatccc acattctaaa actgcttata
     8881 gcatgtatgt agacattgta gaagaaacgt tagtacgttt agaaaaagct acaggagaaa
     8941 atattttaga acgtgtttag gaaaggtgtt gcatgatgtc gaaaactaaa aaagtaacta
     9001 gtgccggcag taatggttcg ggtaatccgt tcggaataaa aagcggtagt ggtggattta
     9061 atataggaca acaaatgtta aaaggtaaag ctggcattaa gtctactggt gataaacgga
     9121 aatctgttag ggtaccagtt gaattatacg atgaagttgt taaagattta tcatacgggg
     9181 ctaaatattc attaatgaca gaaattttag ctttattttt aaaagaattt gaaacacatg
     9241 gaaatagtat agttactgat tttggcaagt tgaaaacgag accagtaaaa atttctgaag
     9301 aagcctttaa agttttgaaa gttataaaat ttgaaacaga tcaatctaat actaatatta
     9361 ttgcttcagc tttgacatgg tatcttgata aaagaaaagg aaaagcataa tgaaatgagg
     9421 taagactatg gatcataaat caaattattc atacaaagaa aattatattt ggaagtatgt
     9481 agtagccgtt tttctactgg taggtggaat tattgcattg gttaaatggg ctataattcc
     9541 taatgcttta gtatttatca attggtttgt ccctaatttt tggagttttt ttggctatat
     9601 attgataatc tggtttatgt ttaaagtact ctcttttttc tggtcgcctg tatattcttt
     9661 gcttggaaag tggtcgtacc taattttaat agcgacagct atttatatca ttatgcagat
     9721 taactaatta tgcagatttt agaagatatt aaaatttatt ggaaaaggat aataggctat
     9781 acattagttc ttcttgtagt aaatttattc ctttcgatga tagcgttggt ctttgttaat
     9841 caaagaaaag acaatgtaac tgaattagta acgtttattt cgtttttcat aagtgggatt
     9901 tttgctcctt tctttgaaga aaccttaatg agaggaatta tccaaaacca attggaatta
     9961 aaaacaaatt tgtctacaag aagcatatat ataattgttg caattttgtt tagtctatcc
    10021 cacttaaatt tatattttat tccttatttt atgacgagtt taattttgtc ttttgtctat
    10081 gataattcag ataaaaggct gattgttccg gttactattc attgttttta caatttaatt
    10141 gtaatactgt taagtgtagt tttttatact tgaaaaaaat agacgaaaac ctaaaaatac
    10201 aaggttttta tctatttttt ttattttgtt tttatctatc aggttgatag aaattgtcat
    10261 aaatgatata attaagtatg aactgattta gtaaaaaaat taaaggagtg atagctgttg
    10321 gcaagatcaa gaattgctaa aattgaacag actaaaaagg ataaaaaaat ttctaaaaat
    10381 aaaacaaaat tctttaaagc tgaagatgtt aagaggatag catggtctgt gaaaacattt
    10441 gatgaagatc gttatgttaa agtttcaatg aatggtctat ttgtacagct tggtaacttc
    10501 agtaatttta aaacgattga tgaactttat ccggaaataa gaaatattgt ggatagtaaa
    10561 ggtttaatcg tggctaaacg gaaatcaaga aactctggtc ttgcttactg taaaaataaa
    10621 gggatcatga ttccggctta aatcagtgaa attgttcttt gaaaacttaa tactactcgt
    10681 actgtagcaa tgttgctatg ttacagataa aagcgtaagg ctaataagca aaatagcaac
    10741 caagcatact gttatttcct ttgccaagag gtatgtaaat acgttagcaa tagaagtgat
    10801 aaggttagta tttcacgcca aaaaatacaa aagtcgatcc attgaaacta ctaattatga
    10861 ggtggcgtaa atggtaatta ttcagaattt ctatctagga agaacctatg aaaaccgtcc
    10921 tagagatcag aatattgaca ctaaaaaatt cagcacagta ataaatgtgc tagatacagg
    10981 gtaactcttt actacaagaa atgtagtaaa gagttgttat gattctttat tacatttctt
    11041 tctaaaggaa gtgtgataat gaaaaaacta aaactgatta gcattgctct attcagccta
    11101 atcactatgt caacggctcg ccaatcaatt gtttcggctg aaggaacgtc tacgaaagca
    11161 gtagtagaag agtctggcga taaaaaagtt gctatagacg acaaagtgaa aaacgaagcg
    11221 gaaaaagcga ctgtggttca aggggcagac ggcttgatgt atgtggtcgt tgatgaaaat
    11281 gatcctgaaa aattgctaga agctgaatct cctttgaaaa atcaacaaga aaataccggc
    11341 gctgttgaag tcggtgttga tgaaaagaga caagaaaagg ctgataaagc taacgaaaaa
    11401 gtgaaaaact ttgacgatat tgattacaac gatattagtt cgttgcagtc agcgttgaat
    11461 gatccgaaat tccctttttt atcggaagat gaattaaatg aaaaattgca aaagacaaag
    11521 aatacatttg agtctgaagc gctaatgaaa aagacaaggg gatatttcag tcaaaggatt
    11581 ttagagttaa gcaataattt aaatgacgta ccgaaaagag cgaaagtgag tcggcatgct
    11641 ttagttagta accgtgcttc acaagtaagt gaaacacgaa taaaccctcc aaatggttat
    11701 ccgtgggtga tttatttaat taggagcaat ggttatagtt atacagaaaa ttatgctatt
    11761 agaagaacta ttgatgggaa agaagctttt tgtttacagg ccggtgtaca agcgacgaat
    11821 acatacactg gttcaacaag tggttatctt tctaattcgc aaagagaaat gattagttcg
    11881 attttatcag catataaaga attaggcggt tgggctaata atgatgccgg aaaacaaaga
    11941 tggatagcaa ctcaaatgct tgtttgggaa aacagtaatg aaaagcctaa aagtataact
    12001 gttacgccaa attggaaaaa cggagctact aagtggaaaa atgatttagt ggctcgtgca
    12061 aatgctatta gagtaagaac aaaatgggat tctacgtcta agacggttga tgagggagat
    12121 aaagcaacct ttaaagtaac taatacttat ggagatcata atttgcatgt gaaatctgta
    12181 tctggtggcg gcaaagctac cataagcaat ggtactttaa ctgttgatac tacaggagcc
    12241 actggaaaca aaatcactgt agatatgatt aaaggttctc acccttcaga cgcgcaccct
    12301 acaacggtat ggagtaatgg ttcttatcaa aagcttgtta ccggttcttt ttacattagt
    12361 acttctgtta cggtaaatgt taagagaaaa ggaactgttg aagttttaaa agttgattca
    12421 gaaacaaaaa aaccattatc aggagcaaca tttagattta gctactcagg taaaacaaaa
    12481 gatgttacta ctgattcgaa tggtaaagca aaattaactg aaaggttgaa agctggaact
    12541 gtagtaaaag ttaaggagat aaaagctcct aatggctacc aactagattc aagcgaattt
    12601 tcaattacag ttaaagaaaa tcaaaatgtt actaccacaa gaaccaataa gaaatccaca
    12661 ggttctgtag aaattgaaaa gataggcgat ttagatggat taggactacc gaatgtagta
    12721 ttcacgattt ataattccga taacaaagtt gtaaaagata acttaaaaac agatagtaat
    12781 gggaaaataa aagtcgatga actgcaattt ggtaaatatt atgcagtaga aaaacaaggt
    12841 gttactggtt atgatcccga tggtaaaaaa tacaattttg aaataagtca agatactcct
    12901 tttacaaaac cggctaaagt gaaagtaaca aatatttatg aagtatccat aagcgaaaaa
    12961 gtatcggaca tgaatgaaag tcaggtatta aaaaataatt ggtctgctga tccaaacgat
    13021 tatcttcaat atgacattac aactggaaat ctaaaaaaat cgggagaaag aaacgtccaa
    13081 agtttcatta tcgaagggtt ttacgacaat aagaatgtag atgtgtcaaa aagtgaagta
    13141 tatgttggat caacaaatgt aacaaactct tttgacatta ataacgatac taacaatgga
    13201 aaagtaattg ctaaggcaaa gacaagcgta ttaacgaata atgattttta taataagtcc
    13261 tataatttac ggatcactat gaaaattaaa aaatctactc ttgaaaacac tgaaaagcaa
    13321 aaaaatttaa cgattgttaa aaatagtaaa gttactgtcg gttcaaaaat ctctaaatct
    13381 gctagctcta atgatgtaga aaccgtttta tattcaagaa aagttactat caatcatatt
    13441 gatgaaaaag acaaacacct tttgaaacaa gatattgatt ataaatacga tggggaaacg
    13501 tatgaatata aacctagaac cgatttattt gataaagatg gaaacaatta taaatctgat
    13561 gtaatccata aagggaaaat tgatggaaaa gatatagttt taaacactcc ctatcatatt
    13621 ccggtacttt ctgtgaatgt ggatcggatt caaattgata cggctagagc tgttaaaaat
    13681 ggctatttac ctacaaaaat agaactaagt aaaaaagaag aatatgaaaa agaattagaa
    13741 aaaattgtat tcaaagttaa aattacagat atagataaca ataaagttgt ttatgatgaa
    13801 aactttaaat acaaagaatt taatagtcat atgtcgcttg atttacctac agaatattta
    13861 acaaagaata aaaaaatcaa ttatagtgtt gatattcttt tagtggataa tccagataaa
    13921 aacaagttcg aaactgaaac taaagattta agaacgatcg gttatacttc ttctgaaaaa
    13981 gttttaacaa acaaagatat gacaaataac caagtcaact attcagcagt agttagaaca
    14041 gtgaaagaaa gagagaataa taatccggtc aaagagttca atgagagtat caattataaa
    14101 tttactgata gcactaaaac aaaaacagga tatggtatat cagttgattt agagccaaca
    14161 tatagaaatg aaattgggaa acaaatagat atgaaagtct atagttatcc gatgaatgaa
    14221 ttgattgaca gcaaaattga cgaaatctat caaagtgggg gaaaagaaac agaagttaag
    14281 atggatcgct taaagaatga tggtaaagtt gagtcgggta ttagtactca aaatctttca
    14341 ttccaatttc cacatatgaa tatcgaaaga aaaactggaa atatatatgc tgacagtcaa
    14401 agaaatgatg aatctattaa gtatgaattg atcgatggcg gtagaaaatt atatgtgcct
    14461 atttggtgtg atttgggaaa ttattctatt gctatcaaaa gtagtaactt tggtggtaac
    14521 tatatctcgt tggatatgaa ccagaacata gatgtttatg cttatatgta tgcaacgata
    14581 gatagtgaaa caaaaaaaga tgatgaatta ctgcttgaac ctgtttatcc agagtctact
    14641 ctaccagatg gttggagcaa aaatgagatt gattggctga ataaataagt ttgaaaagtt
    14701 tttatctatc tgatagaatt aaataatgat atagggatgg tgatagaatg agggttcaaa
    14761 gctatggtaa cagtgtcttt gatgttaaaa gagaatttca agattctaga agaaaaacca
    14821 aaaagctgat agcttacttc attctatcag ctatcgtttt ctatattgtc aagtttgttt
    14881 tggaattaaa ctcaatagta ttcacagata tggttcataa aatgttaaat ggagaaccta
    14941 ttaatttcaa ctttgattac atgcttgaaa aagcacaaag caatcaaatt gtggctttta
    15001 tcgtgagtat ctattatttt attgaaaaat ctattttttc tttaaaagat tttttctttg
    15061 aaatgcttac caaactaaca acgttttaca ataaaatttc aaaaaattaa ggaggaagtt
    15121 tgaatgttag atcaaaatac agacagaagt tggtggatga ttggtgccgt gatcgtaggt
    15181 gccatcttaa tcgggacagc taaagtagct tttcccgaag tgtttaatat cgtcattaca
    15241 tttttcaaaa acatgatccc tacaaactta ggatagttcc actaaaaaat tcacgtagtt
    15301 tgatgcgtag aaaaataata aagaatgaaa aaggctacat aaagtgattt atgtagcctt
    15361 ttttttggat ggaagtgatg taatgctaag agatatgccc aaaatgattc ttttaatgtt
    15421 tgttgggttc tttttaattt tagtgattgc gtactattca ttaaatggct atacacaaga
    15481 ttcgtctgtg aaaggtatgc aagaaacgtt aagaactaca gcaatagcaa acagggatga
    15541 tagtattcga gtagaaaaag gacgatttgc tttaattaag tctgattttg aaaaagattt
    15601 taaagaaaaa tttgggaaaa gtaaaaatct aaataatgaa accgctgatt ataaatttga
    15661 ttatcttaca gatgggaagg acggtattaa agcaattaaa gtgaaggttg aaagtggatc
    15721 aaaagaatat caagcaactt gtattttaaa tgttgcaaat gattagaggt gtgaaatttg
    15781 cgtgttgtag aggaaaagaa gatttctcca aaaatcgagg aaactcctaa aagtaaaatt
    15841 aatatcgcaa gtattattaa aaaaaatgga attaaagaaa actctgaagc gatagaagga
    15901 aaccttgatt ttttaactaa gcttttagaa gaagatagtg gaaattatga accaccaatt
    15961 gaagatgcaa aattaaatat gattcgtgat gatttaacca gaaactattc ccaagaagtt
    16021 ttacaagctt taactgatga tgaaattagg cgaaaacttg tacaagttgt tttgaaagaa
    16081 catggtactt tctttaaaaa agataaagag gttgcagaat atgtagtacg tgaatgtatt
    16141 ggaacaggga ttattgagcg aattatgacc aacgatgaaa ttacagatgt tggttggaat
    16201 ggctctcaac ttagcattga aactaactct aacaaatggt tgtttgacgg tgataaatta
    16261 aatatcacgc aagagtatat tgaacgtgtt atttctaaat atgctgttgt aaatgatcgg
    16321 gcttttaata gtggtaatcc tatcatggat ggaatgttta aaaatgttcg tatatcagct
    16381 acacacatag ataattcacc agatggctct acgttttcta tgcgtgtggc aaggcctaga
    16441 ttagcattga ataaagaaaa ctttgaagat tttgctcctg attatatttt ggagctattt
    16501 gagaaaatga tgaaaacaaa agcaaatatc tgtatatcag gggagacagg tacaggtaaa
    16561 acggaacttc aaaaattact gctaagtttt attgataatc atgatcgtat gattatgatt
    16621 gaggacgttc aagaaactca cgctaaagaa ttatttccgg ataaagatat tttctcttgg
    16681 atcactactc ccaaaaaagc aatttcagat ttagtaaaag cttctcttag aaataatcca
    16741 cgatggatca ttgtttcaga aacacgtggt tctgaagctt atgaaatgct tcaagcggtt
    16801 ttgtcaggtc actatgttgt aacgacactt catgcggtta atgcacgtgc gatacctaga
    16861 cgttttgtaa atatgtgtgc aagtggtttt aaaattaacg aaaatgcggt tgaggaagac
    16921 ataaatcgtt atttcgattt tggtgtccat atcaaaaaaa cagtggttga tggtaaagtg
    16981 atccgttatt tgaatgaaat tgttgaattt tctgctagtg aaccgactac agtttttaag
    17041 caaaaattta tcaatggaaa gtttgtcatt gaaaatggta gtctttccga agattttaaa
    17101 gaaaaaatgg ctgaaaaatt tattacgttt gaatttcctg aagatcaaac taatacagaa
    17161 gaatcacttc ctgaagaaga agaggtgatt taagttgaaa gtacaggcta tgacaaagcg
    17221 aaaaggtctc atggatgttt cggaactaaa cgcctatcaa gtagcgtatg gtaaaccgtt
    17281 agattataga gattatttga actatgttgg attaccttgt ttgtttatgg gtggcttttc
    17341 ttttgcttta tgttactact ggtggattgc tttgatttgt ggagtaattg gaggcgtata
    17401 tggctttaaa gttataatgc ctaaaagtat taaacgctct tatgaattaa agagtttaca
    17461 ggaaagaaat aaatttatta acaacatgac tcaaattttg accgatgata gtaaaacagt
    17521 tactagagcg ttatctatag caaaacagcg aacaaaaggt gaattaagag aagatattca
    17581 aatcttagaa tcacgtttac aaggtgctga taaatttcag attgctgaag cttttcgtga
    17641 aatcaacaat aaatattata gtgatgttgt ttttacacaa tactttgagc aattggaaac
    17701 agctatttac gaaggtagaa ataattcaga tactatgaag caaataaaga gctatcataa
    17761 tgatgtgaaa cgtaaaacag aaggttttat gaaaatcaaa gacggctatc ttcaagatat
    17821 gaagcaaatg atgtttattg tagctgtttt tattggagct ataacttttg cttttggttt
    17881 ttctactttc tatgaaggtt ttgctcgatc acctatcgga tgggtatttg gatctattta
    17941 ctttttgatt atggttagct tcatgaagtc atttttcaaa cattattttg atgatgaaat
    18001 aatgagtttg ggggtaagta attaatgaaa gttaaggctt taaaaaagaa aagaaaatca
    18061 agtattagcc ccttgaaaat tacgaaaaca gaacataaaa gcttttggat taaattacta
    18121 ggtgatgttt attatcaaaa attacgtgaa atgaacaatt ccaatattgc gattattaag
    18181 tggcaaaaac aacggttaaa aaagtcattg atttttatcc tagtcggatt cttaatgtat
    18241 ctatttttag ggaaagaatg gtattactta gccggtggaa ttgctacttc agtaggtttt
    18301 tatgtttggc aagcaaaatc aatcaatggt atctataatc aatttcggtt tgaacgacac
    18361 ttgcaattta gtaaatttac acggctattg atcccctatc tgaaacaaaa aaaagatggc
    18421 ggaaatttat atggtgtttt tgcaaaaatc gtaaaaagac tagattatga taccgataaa
    18481 aagctattaa tgaagcttat gcaagaaatg acagatcagc ctaacgatat tagacctttt
    18541 acggaatatg cagaacagac ttctggaaca gacatgtccg tattatttat gtctacagtt
    18601 tatgatattc gacaaggttc ggcagatttg gatgttattg aagagttgga tcgtttagct
    18661 tctgaagagt taatggccgg aatcgattca atcattgact ataagtcgag gcgttttgtc
    18721 ttctttccta caaaaattgc aatgacttca tttattttag ttgtcggttt tgcagtaggc
    18781 gttcttttca tgaacctaaa agatattaac tttgggcaat aaaggaaagg agaaagtcaa
    18841 tgcaagaaca atccgttatg gaaatcatta aatggtttat aggtttaatg atgattatgg
    18901 caatggtttc tataggactt ttttgtgttc aattacaaga tattaatact ttcaagcaac
    18961 aagtaaatta tcaaattgaa cgaaaaggag gtctgacgac agaagctgtt gaagcaatcg
    19021 acaaatattc ggctactaat tatgatagac gttttacaat tgaaagcgat aagttaaatc
    19081 agaaagtatc ttatggagaa gaaattgatt atacgatcaa agcaactatt ccaattcaaa
    19141 ttttaccgct tcctgatgta actttatcgt ttaacggaaa tagtgtttct caaataagat
    19201 gagaggaagg ataaaatgca agagaataat gtttccagaa taatttattt gattggcgga
    19261 ttgataattt tatccttagc tattgccggt cttgtagagc attggccgga aataaagtta
    19321 ttaataagaa acttttacga caataaaatg attaaaatgt aggaggtata gatttggaag
    19381 caattcaaga aaatcgtaag gataatcaag aaacaagtga aaaaaacaaa aaaaaaagaa
    19441 aaaagaaagt agataaattt acggaaatga ccgataaaat cattgaaaag aaaggactta
    19501 aacctaaaga ctttgaccgt caagcaatca aagaagcacg acaaaaactg tatgatgatt
    19561 ttgttaaaga aaacatatca cagcttttag actaacattt agggggaaat aaaatgaaaa
    19621 atttagttat cagcaagttt gcaatgttac caagaatgga ttttttcgat aatgtaagta
    19681 agtttatgtc aaatatgact tcaaaactac aaggaatttc actatctgta attatctttt
    19741 gtattgtggt tactggtttg atgtttcttt tcggagaagg gccaagtcgt actgctaaaa
    19801 aatggttaac ttatatcgtg attggggcaa taattatctt cggagcttca actatcggac
    19861 aaacgatcaa gtccgttggt ggtttctaag gggaagcttc ttagaactaa aaaattcgca
    19921 agtattgcat gaaagagcat tgagtgatta atgctctttt ttattttgaa aaactataaa
    19981 ctaaggagat ttaaactatg aaccaacgat tcgaatataa ttttgaagat gtagaaccta
    20041 agttactgaa aaaaggaaaa ggattaaaaa agaaaaataa atatactctc aaacaagcag
    20101 aagcattagt aggatggatt caacacaatt ggtcagacaa gacaacaatt accttgatct
    20161 gttcagacac agaagaagga acaaagtatg cttttgatgg aattgaaatt actccatttt
    20221 cgattggcgg acaagaaaaa ttattgtttc ctgatattga aggacaaatt ttacaagcgc
    20281 cggacagcat gatttccgat cctaataaac tgattttgga tattaacgat caatacaaac
    20341 acgaaccaga cgtagcagaa ccaacaaaag aatcaaagtc aaaattaaat ttgaagctcc
    20401 cttcagtagt attaccattt gctaagaaga aaaataaact tatgaacgaa ttgattgaac
    20461 cagaagaaac ggatatttat gaagaagaat tagaagaaca agaagagatc gaagaattag
    20521 ttgtgtcttc tgaagaaaca gaagaagtag aagaaattga aactgtttct gaaaatgaag
    20581 aagaaacaga agaaatcttt gactttgaag atgaagaaga agtggaaaat gtacagaaag
    20641 gcgatctatc tacaagtagt caaaatgggt tggaagctgt aaatgatcca caagttccac
    20701 catatatatc ttcacaaact cccaattact ctccacagta tcaagcgcct aatgtcttac
    20761 aaccattaag aaaacacgaa acagtgcagt tagttacgct taaagagtac tgtgatttgg
    20821 gagaagaaat tgaaacttca atttctcaaa tggtcgaaaa gttgaaacca gaatctttat
    20881 tcaaattcat agggattcct tctacaggtc ttacaaatac tcgtattgat gaatatagaa
    20941 gtaaccatgc tatgttgcga ttagctgaag taaaatttga aaatttaaga gagcattatt
    21001 cacggcaaat tatttctttt aaagcagaag ccctagatcg tttaagaact gcggtagata
    21061 ttgcttggaa gaagccttac gatttagatg tgaagaaaaa caaggccgaa gagttatcaa
    21121 aaatggaagc agaagcagaa gctaaattaa atgagttcgt gaaacgtcag gaaaacaatg
    21181 taaatgataa aatcaaaaag tttgagatcg aacaagaaat agatttaaaa aactttattg
    21241 caagacaaga ggcagataaa gcggtattta ttgctacaga gaaagatcgg actcaaaatt
    21301 taattgattc taaagcggaa tcaatcaatg cagatttact tgaaacaaaa gataaattta
    21361 ttgatgaaga aatgtacaaa atgaaaattg aaatgaacaa aaatttattt gatggcaagc
    21421 aaaaaattaa atcagaattg gctactgaac tcgctaaggc aaatgataat gtttgggaaa
    21481 atgcgctgaa atttattcaa gaaattcaag atgaaattga agctaaaaca ccaatttggg
    21541 ctgctgaaat caaggagttt aatagtttag aagaacaaga acatgaacgt atgaagcaaa
    21601 ctaaagaact tcaattaaaa gaggaaagta ttgaaatcaa gcgtttggaa gctgaaatga
    21661 atttgaagcg tatggaagaa ttagatcatg aaaataaaat gcttaaaatt aaacttgaaa
    21721 ctgccctttc aaaaaatgag ttattagcta tggaacaaga tacaaagcaa gtggtgaatg
    21781 gatcaaacag agttggtgca cttaatttat ttagtaaacg ttaaaggaga acggatatga
    21841 gtgtttttaa taataaagtt atgttaggga actgttatgt gaaccacatt ggtttttacg
    21901 atggaggaac atacagagtt ttattcttac gtttatctgt ttttagttac tcaaaagatg
    21961 gaaaggggca ttatgaaaat attaatgcac aaatttcttg tcctttagat agaaatgggg
    22021 aaaccacgac tacaagtagt caccctaaag ccttgatgaa taaatttatc tttgaaaagt
    22081 tggatcgcaa tttggttgag gggatgaaga taagtattca tggaaatatt cgtggaacag
    22141 aacaagtgct tcttaacagt ggttggaaaa actttggtca attatcgcct ttagaaaaag
    22201 aagaatatca aaaaattcct aaaaatgaat tagtaacaag aaatcaaaca tatatctata
    22261 tagaagaggt aagtatgcca gaaaaagaag aatttagaaa gtctcaatct aaggtaacaa
    22321 aagaagatgt ggaagttgca gaaccgaatc aagcagatga aattttatcc gatgatactg
    22381 atccagtgaa tgatgaagga gaggttattg aagtttttga agctgaaatt atcgaagagg
    22441 aagaagaaat taaaagtttt gataaaagaa tgtatcgaga gaaaccaaaa ggttatgtga
    22501 attttgaaga tatgtattat gacgaatatt ctaatgaacc accgatcaat tagtgggggt
    22561 caaatatgaa gctagtacaa aacaatgaag tgaaagaaat aaaaaacggc tttgttaaaa
    22621 actcgaacaa aattttggga aagctgaaaa aagtaggtag tttcaaaaaa aataaatatc
    22681 atactggaaa aattgaggga gaagatttac caaaaagttt acaagataaa ttgaatgttc
    22741 cgcttgtatt tataggtgtt tttttaggtt caatagtttt tctagcaata acgtacttat
    22801 tgaacttttt aaaagctttg ttagttgcaa tcggacagtc agaaagtggg ctacttggtg
    22861 tagagttcga tcctaagttt agtttggcat atctaaaacc acttggggat acgaaacaat
    22921 actttatgtg tgctgtggtt gcggtaatag gagtcgctta tttaatatat gggaaattaa
    22981 atcatgaaag tgagaaaaat cttgtttacg gtcaaaaagg agattcaaga ctttcaacta
    23041 tcaaagaaat taagagagat taccatgaga taccagaaaa aacagaagtg tatgatggta
    23101 ttggtggtgt gccaattagt cactatcaag ataaatatta tattgataga gacacagtaa
    23161 ataccgttgt tttgggagct tcacgatccg gtaaagggga aacatttgtt gttcctttat
    23221 tagataatct tagccgagca aaaatacaaa gtaatatggt cgtgaatgat ccgaaaggag
    23281 aattgtttag cgcttcaaag gaaacacttg aaaaacgagg ttatcgtgta ttagtgctaa
    23341 atattgatga tccacttgaa tcaatgagtt ttaatccttt acaactagta attgatagtt
    23401 gggctaacaa ggactatcac gaagctagta agcgagcgaa tactttaact tcaatgctct
    23461 ttgcttcagg aatgggtaca gataatgagt ttttctataa atcagctaaa tcagcggtca
    23521 atgcgattat tttaacgatt gtagaacact gttttaacaa tgattgcatt gaaaaaatta
    23581 caatgtacaa cgtggctcaa atgctgaacg aattaggaag cttattttac actgatccaa
    23641 agactggaaa agaaaaaaat gctttagatg aatatttcaa tactttacca caagggaatc
    23701 aggccaagat tcagtatggt tctacttcat ttgccggtga taaagccaaa ggttcgattt
    23761 tatctactgc ttcacaaggt attgaaatgt ttacaagtga tttgttcggg aagttaacaa
    23821 gtaaaatgtc tattgatttg aaagagatag gctttcctaa gtccatacaa tttaaagtca
    23881 atacgaattt agttggaaag aggattagta tttcattttt gagaaaagaa aatgatgtaa
    23941 ttagattaat taagaagtat cgagtgaaag taaaagcttt agggctatgt gttttaaatt
    24001 ttaatgaata tcttcaggat ggagatatgt tggatatacg atatgaagaa gagaaatcga
    24061 gagcatggta tcgtattgaa tttcccaaaa aacaagcaaa tagtcatgat acttctttag
    24121 tcactaaaaa attcaagtca ggtaaaaatt attctgactt agaaatcagc accttacgat
    24181 taaaatacac ggatcagcca actgctgtgt tcatggttat tccagattat gatccgtcaa
    24241 atcacgtact tgcaagtatt tttatcagtc aactttatac agaattagca agtaattgta
    24301 agcaaacacc ggataaaaaa tgttttaggc gagttcattt cttgttagat gaatttggga
    24361 atatgccggc tatagacaat atggatggga ttatgacggt atgtctagga agaaatatgc
    24421 tttttgactt agtgattcaa tcctatagtc agctagaaac aagatatgat aaagctttta
    24481 aaacaattaa agaaaattgt cagaatcata ttttaatcat gtcgaacgat gaggaaacga
    24541 tagaagagat ttcaaaaaaa tgtggtcata agacaacaat aaatagaagt gctagttcta
    24601 aacatttaga tactgatagc tcggtcacta gttcggcaga gcaagagcga gtaattacag
    24661 ttgagcgtgc tagtcaattg attgaagggg aacaaattat tttaagaaac cttcatagac
    24721 aagatacaaa aagaaataag attagaccat ttcctatttt taatactaaa gaaacaaata
    24781 tgccgtatag ataccaattt ttagcagaag actttgatac tcaaagagat attaatgaga
    24841 ttgatattgc atgtgaacat atcaatctat ctttacaaga taaccaaatt ccatatgcaa
    24901 ggtttatcaa agatttaaaa acacgtttgg agtattcaat tattaataat attcctatta
    24961 gtgaagaaga ctatcaggat tatctaaatt tatcaggatc acaacaaaca attaatgaag
    25021 aagagctgtt aaaactggta aatacggaag taaaaagtca agatatggaa ggtcaagttt
    25081 tatcagaaca agaaatgaaa attaatattt atctaaagga aagtcaaaag gaagcaatag
    25141 aattagtaaa agtaattaat ggaaggttag ctgatgaaaa ttcagcagat atggttataa
    25201 aaaccattaa ttcacaaatc cttgatacgc ctttcattca atctttaatc aatgattcta
    25261 tagctattca taatgttcaa gagagtaagg atcaaattat gatcctagaa caacaattag
    25321 ctaatgctta tgagttagca gtgtttaaaa cgaaaaattc aatactgaaa aataaaatta
    25381 tcaagttgaa aaatgctatg actaagctag caaaagcaat ttagagagaa gggaagaaat
    25441 attgactgaa tctattaatt ggagaaaact aaatgtgcaa tggttaaagt ataaatggcc
    25501 aatcatagtt tccctaataa tcattctatt tatggcctat ccgcaacgag tttttgcgtt
    25561 gccgtggatt acagacaata aagaggtatt aaaattttta acaaaatatc aagattatct
    25621 tcagtttact aaaggtggtt ttggaagcat tgtcgttcaa agtttatcgt gggggctgat
    25681 tagaggtgca tattttgttt gtaaatcagc agaaaacctt gttccacaat cgctaagttt
    25741 gtttagcttt gttgaaagca gtagtttagg tgctgtttat caatctgtat taaacacggt
    25801 ggttgtagga ttaatgatcc tttcattgat gtttgttggt tacaagatga ttactggaaa
    25861 aggaacagtg gatttaaaat cggttggaat gaacgtagtg atgtctatag cattaatact
    25921 tttaatgcca accatgattt ctagtggtat tcaatttgct aaaacatttt ataaggactc
    25981 tactacgatt acaaaagctg atgggggcgt tgcttggtca ttgattgagg acggtgtaac
    26041 tgatttagta tatatcaata aaaacgatgc ttatgatcgg ttgggtaaag atggcgtaca
    26101 aaaaaatgcg ttaaaagaaa agaatttctt ttcctacgat ttcagtgaag taatcacagt
    26161 tgatacagct aaagatttag aagatgataa taaaaaagct gaatatcttc aatctaggtt
    26221 gacaccagat ggcgaaggaa atatgcaagc cgttaagatt gatgatggtt ggatgtcgat
    26281 gttctctgat agtttcaaag gagggtacta caggtttact aaaaatactt ttgcattgac
    26341 tttaggatta ctttcgttag ctgtagccta tgtttttagt atttttatca tagtcaccgc
    26401 tattttagaa ctggcattta agcgtgtgtt aggggttctt gtttttgcaa cagatattga
    26461 gacaggacag cgttcaaaag ttgttctatc agatattcta cagtgctatt tgactgtagg
    26521 ctttcaagga tttggattat ccatgtttgc aatgtttgtt tcctatttag gaacaggcgg
    26581 agggtcttcc gttaatccgt ttattaaggc tgtagcttat gtatgtgccg tttttgtttt
    26641 aatcaaaggc agtggaacag tcatgagata ctttggtgtt gatattggac tcaaagaagg
    26701 ctatgggcaa cttgcttctg cttttggaat gggtgcaatg ctgtttagaa aaggatcaaa
    26761 tggatttaat cgtgccaaag gaagcggaaa cggaaatgga tcagacagcg gagaaggaga
    26821 agatcgaaaa ccagaaaaga atttcggtga aactctatca aaaaaagctg gcaaaactgg
    26881 aagagctttg ggatatgccc atgaacgtgg attatcaggt ttagcttcag atggagctac
    26941 aatggctagt gaaagagcaa caaaaccatt taagagtatg cgtgaaatgg ctaatgatac
    27001 taagaataag ttcaaagaag gtttagatga tggtacagtg tccgctatta ataaaaatag
    27061 caaacctatg ttagctaaaa ataaagaaga tgaaactgga aaatacgctg attccatgcc
    27121 aacacgtctt tcggatagaa aagatggtgc taaggttgaa aatgccgata gaattatgtc
    27181 tagttctgaa cgtatgcgtg aagcaatgaa aaataatgct gaatcgaata ataatcctgt
    27241 aagtgcaatt cagcaaaaag ttcaacaaga tattgaagaa cgtaaaaatg ctatgcacgg
    27301 tcaagctaag tctgctgaag aattaattaa tcagaagcga caagaagcta aatacacgcc
    27361 tgaagcaatg aatcgtgagg aaatgttaag gaaacgtgta gaagggcgta caggaactaa
    27421 tacggacgaa aaagaagcgt tgaccaaaga aagaatccaa gaagctaaaa actcaaatac
    27481 cggattagaa aaattggtca aagaaaatct acaaaattct acaagtagtc aaggtggtcg
    27541 atcagtagat gtccgagaaa atattcaagg ttcattgaat ggtcatgtcg gacggaatgt
    27601 tgatgtaaga gagaatttac aaagttcttc aaatggtcaa ggtactaaga caattggtgt
    27661 tcgagaaaat ctgcaaagta gcagtacaag tcaaccaaaa acagtagatg ttcgagaaaa
    27721 tgtacaaaat tctacaagta gtcaagggtt taaatcagtg gatgttcgag agaatgtgca
    27781 aggtagcagt gcaagtcaac caaaaacagt agatgtccga gaaaatgtac aaagttctac
    27841 aagtagtcaa ggattcaaaa cagtagatgt tcgggagaac gttcaaaaag atagtggaga
    27901 aatgaaagaa aaaacacaaa aaatcaatat cgttgaagac agaaagtcag cgaaaaaatt
    27961 tgattcaaat catgaaacag tgattattga tagtgaaatc cgtgaaaatg ataagggatc
    28021 aaaaccaaga cgaagattca cttatgaaga caacgaatta ttcagagata cacttaatga
    28081 tcctaatcca cttttcgata atttaaatta aattaaaagc cggcatgagt gattatgccg
    28141 gctttttatg aggtgaaaat gatgtataga aatcccaaaa atataaaaca agagataaag
    28201 ctatttttct tctatttagt cgatttagga atagtagccg gaagcgtgat ggcaagtgtt
    28261 tactttgcaa aattaatgcc aatttcacca atgatgaaat ttgcactgta cttattagca
    28321 tttgtagtgg gtgtttggat gtgcgttaga acgcctaatc accctaaaga gcgaaatatt
    28381 ttaatgctgt attatctctt taaaatggat agaaacagat accacgaagt agagtttaaa
    28441 agaaatagta gggggaaaat tgaattatga ttgttgctga aagtaatgaa aataaattaa
    28501 gtggtgtttt tgacaaattc ttagaactag ttattccaaa agataaagat atgtgtgaac
    28561 ttttaccata taaaaaaata ttgaaagacg gaacgttagt gactaatgac aataagtatc
    28621 aagccttttt taaagttaaa acaactgact taacttctat ttcagaagat ggatttatgc
    28681 gtatggtaaa caaactcact tatttaaatc gagtatattt agaaccatat aaaatttatt
    28741 cattaactta tcctactgaa acagtaaatc aagcgattta ttggaagcat agaatacagg
    28801 aggcaaagag aagtttattg agtaataatg atcccaattt agaaacgtat ctgaagtgga
    28861 atctaaagct agcttacgat aattatgaaa gagttgatct agtatcgact ttaccagagt
    28921 tgatgttcgt tatttgtgtt tatggaaaaa cacaaaaaga agtgaaaaat catgccgatg
    28981 taatgaaaca ggccggtggt agagaattag atttacaaag aattactgaa ggggatttaa
    29041 tcaatgtgat aactaaattg atgaatccca atacttcttt ataaggcggt gcttattatt
    29101 tgttaaagca ctgtagaaaa ggattttgta aagtaattaa aggtaaaaat gctgctgatt
    29161 taatctttga atggaaagaa tctaatttaa ttaatgtacg tgggaaaaat ggaagcggaa
    29221 agacagaaag agtgatggct agtattgata attcaaggcc tagatcaaga gcattagtaa
    29281 taactgatga aaaaaatcac tataaaggca tacgaacgat agaaaaaaaa tatttaacta
    29341 acaatgattt aaaagtagta gatgatattt taaatattta tcctgatttt aatttagttg
    29401 tttttgatga aacaattcct gtgacagaaa taaaaggatt ctatcaaagc ttttccaatc
    29461 tagcaaataa atatgaggaa gttctgtttg tttggattac agaagaagat agtaatagca
    29521 agtcagcgtt ctttagtgaa aagaacgctt ttttacattc tatttaaaaa ggagaattga
    29581 acatgattgt aagtaaaaaa ctagcaagaa atctagtaag tgaagggtat gacttaagat
    29641 tagtagaaaa gtatcaaccg agcggtggaa ttaaatttga tgagcgttat atttctactg
    29701 gtgatggata tgtaacttcg attgctgtta ttgagtttgc agaagatgta aatagtcgat
    29761 ggttaacgga tataatggca attccaaata ctattgcaac tttcgatgta tgtacggcgg
    29821 ataaagaaga cttattacac aaaatcaata cgtctattgg agaattagat taccgatcaa
    29881 caaatgagaa tagaacaact gacaaaacag acgctttact agataaatac aatttagaag
    29941 attttgcaca agaaattacg aaacgtggtg aagttgtcaa aactgttcat gctcgtattt
    30001 ttgtttatag cgattcttta gaagaattag agaaaagaat tagtgagatt cgtaaagatt
    30061 tggctagtgt caatcacaag gcaattgttc cgcaatttag aatgaaggat gaatggatgt
    30121 ctttatttca agatggcatg gaacaagaat caaaattatt tgccaagaaa ggcttaactg
    30181 ttccggcaaa aaatattggt ggcggtattc catttcacca caagagtttg aaagatccac
    30241 gtgggtttta tttaggaact acgtcaactg gtggtgcttt tatatttgat ccattttatt
    30301 ctacgaagca aagacggtcg tttaacggct ttattttagg aaagatgggt tttggtaagt
    30361 caactttaat taaacagcta caggaaggcc tacaagcgaa aaattgtttt attcgaggat
    30421 ttgacaagtc aggtgaattt gaaggcatgg tgaagaaagc aggcggtgta tacgtcgatt
    30481 taggcggtgg tgatatggta gtaaatccat tgcaaattta tgcaacagtc atgaaaaaag
    30541 atcaatttgg aaatgatgtt gtagatgaat caaagagttt tcaaaatcat atcactaagt
    30601 gtagtaatca aattcgcttt ttagaacctg aaattgatac ggcaactgta cgtgaatata
    30661 ctttgatgtt acaagacttt tatattcatt atggaatttt gccaaaagaa tggagagaag
    30721 cgagagacga caacgaacga aatcaattaa atacaaatat ttgtaacttg cctaatgatt
    30781 catatccaat ctatggagag tttcttaaat ttattgaaaa tcaacaattc aaaattaaaa
    30841 atgctactcc tgaacgtgtc cgttctattg agctaattaa gcttatcgtt acggatatgt
    30901 gtacaactta tccgcaaatt ttcaacggag taacaacaat gccaaacttt gatacaacaa
    30961 aaattgttta ctataacatt gattctatta gtaaaatgag tgccccagta ttccattgcc
    31021 aattatttac agcgttaacg actatttgga acagtgcctt gcaaaacgga aagattcaaa
    31081 aagaaaactt taaaaaatat ggcagtgatt attataagta tgcacaagat ttcatggttt
    31141 tgatcgatga gtgtcacaat gttatcaatt caaataacaa gtatgcttgt gaatatgtac
    31201 taagttttga gcgagaaatg cgaaaaatgc gtgcaggtgt ttattttgca actcaaacgc
    31261 ctgaagaaat tatccctaaa gattctggat cagaagtagc agatgtgatt agaaacattt
    31321 ttaatctatg tacttttaaa tgcttcttta atttagattc tgcattgttg gaagacataa
    31381 aaaaagtttt aggaaataca attactgata cagaaattat gcttttacca gaattagaag
    31441 taggacaagc tgtagttcaa acttccagtg aagacaccta tatgattaat tttgatccat
    31501 atccagagca aattgaacga ttcgatggtg gtcaataata gaaatcggag gtgaatttaa
    31561 tggagcagaa caaaaataat aatgttgctt caacactcgc tcgtcaaggg atgaagcaag
    31621 tatcaaagaa aataggtctt gctttaaaaa taaaaatagg ggtagttata ggactgataa
    31681 cattggttgg ccttttagtt ataggttctt tagctacatt acaaggaaca caaactgcaa
    31741 ctaatacagg aggtgcagaa gtcattggtg gcaacaaacc gttgtcacct gaagttcaaa
    31801 aatggcaaaa aacggtagaa aaatatgctg aaaaatacgg aattaaagaa ttagtacctt
    31861 atgctttagc aattatgcaa tgtgaatccg gaggtaaatt gccggattta atgcaaagta
    31921 gcgaatcagc cggattgcct gtaaacacac ttcaatatga agaaagtatc gatcaagggc
    31981 taaaacattt gagtaatgtg tataacattg ctaaaagtta tggcatggaa agtaactatg
    32041 atggaatagt tcaagcttac aattacggaa tagcttacat gcactactta ggaaaaaaca
    32101 aaaaaacaca tactatcgaa acggctgaag cctactctaa aaatgttgtt gctccaagtt
    32161 taggaaatac tacaggacag acttattcat atgtaaatga agtatcaatt aaatatggaa
    32221 aaacatattt gtatttaaat ggtggtaatt tttactatgc agagttagtt aaacagtata
    32281 tcggtggggg tagtggtaat ccggctaatc cttcagaatt ttggggaaaa atgaaaacag
    32341 aaatggaaaa atatcaaggt tggccttatg tttggggcgg taaaaatcca acgacaggtt
    32401 ttgattgtag cggattaaca gcttatcttt atcaatttag cgccggaatt acaatagata
    32461 gttatacagt aacgcagtat gaagcaactg aagcagtatc aattaaagaa gcaaaagctg
    32521 gtgatctgat tttctttaga ggaacatatg gagcgcctga tttcatttct cacgtaggta
    32581 tttatgtcaa tgaaacaact atgtatgaca gtaattcaag cggaattggt tatcacaatt
    32641 ggcaagattc atattggcaa tcacatagtc cagagattcg tagagtcaaa aaataggagg
    32701 aagaaaatag atgattaaga gaaaaaatga taataaatgg aaatatattt gtggtgtttt
    32761 aattattatt ttagttttag gtggattgtt atctcaactt catacaagta acattcaagc
    32821 aaaaaataaa aaattggatc aagaagttac acaactagaa gaacaaaata gcaagttaag
    32881 taaaaatatt agtgatctaa atgcaaatgt agaagcgaac ttaactaatg atgatggcag
    32941 tgaattaaat aaacaaattg ctgaagttgc taagaaattt gttgagctat atccggtata
    33001 tgatattgaa aaagtagaag aaaagaaagc tgatttagag aaaatagcta ctccttctgt
    33061 agctgattct atcgtgccgg acgacatgat tacaacgagt aaaaagactt tagaaagtaa
    33121 atctactact caaaaaggag aagcatattc aagtgatcca acattcaaaa gtaaatataa
    33181 agattcaaaa ttatatacga attatgttaa cgccaatact attaattatt ttgctgaagt
    33241 aaattataaa acagaatctt ctagtggaga tacagaaaat acagtctata tgctttttga
    33301 agtaaccaat aaagacggcc aagtgttggt agataattat gaaatcaagt acttaaaata
    33361 gtgaggtgaa gtatatgaat aagaaatatt ccattcataa taagaaggaa ccaaataaaa
    33421 aaaataaggc acaaattgac aaagtatata aaaaaacgaa aggagtaaaa ttatatttag
    33481 gtgctatact tggattttta gcaataggaa tgataatcgt tttttctcct tatgtgatgg
    33541 ggaaaagtta tgattttgaa actgtaaaaa tgagttcagc ccaaaatgta acgtcttctt
    33601 tgaatatgta tgttgatgat atggaaataa atagggaagc cggactgttt aaattagtat
    33661 tgcggtatca agatgataca ggtactaaat cactaagtaa tattaaaagt gactataaat
    33721 taaattttat aacgaacaaa aataatgaag atgttaagac aaaagttgta aaattgtcag
    33781 atgaatacac ggtaatttat tatcaaaatc tgcctaaaga ttttggtgta atttctgtga
    33841 cagttaaccc tagatatatt tatcctgaat tagaaccttc aaatgactta aaagaaaagg
    33901 aaataaaatt ctatgcagta gacaaagata ttaaatcaaa tgctaaattg gaagttgaaa
    33961 gtacttctga tttgcaaaaa gataatttta aatatcagat taaagctata gaaaattcta
    34021 taaaagatga gaaaaaatca attgaaaaaa tgaatttagc aaataaagta gtgcaaaaag
    34081 atattgataa agctaatcaa aacttagaat ttcaaaccct agacgaacaa acagatacaa
    34141 aaaatgaaat cagttctatg cagacgacta ttgaaaataa taaatcttca atagaggaaa
    34201 gtgaaaataa aatcaaacaa tttgaggaaa aaataaagca actagaaaag tctgcaagcc
    34261 gatttgagtg atcgtgttta aattatttta agggagttta gagagaatgt gtaattctat
    34321 tgtcactatt caagagaaag ctgaagaaga attaatgaga attgaagcgg aatataaaga
    34381 aaagagaaaa gcgattaagc gcaaaaaaaa tgcagagctt aaaaaatata aagaggaaca
    34441 agcgttaaaa ttaggaatga tgttgtgtaa atattatgat tgctatgata taaacgaagt
    34501 gctaaaaaaa gcgaatttaa accaattttg tgaatagaaa agagagtggc aaggtaaaac
    34561 ttgccactct ttttttgggc gtaaaagctt tagttactat gaccaaaact acggacgaaa
    34621 ctatgaccaa aagtaggtac tatattatga ccgaaaatag gtcgaaaatg gatttttttg
    34681 tgatagcaaa aaatatgaag ctattttgaa agaaaaccag ttggcacagc caacttagcc
    34741 accttccttt aggaaggtgc tatcagtttt cccttatgct ctttgtatta attccttggt
    34801 cttgtcttta aatctttaat tttcctttgg actttgatat aataatatat accagataga
    34861 taaaaacagc ttgaaagagg tgtgtgtatg gatgtttcaa tcagaggaat tgatccacaa
    34921 tatgtaaaag agattgataa aaaagttaat aaaattcaag aacgtaccgg aaaaaagttt
    34981 agtaggaatg actatttttt agcaatcatt cgccaagata gcgagatcga tttgattgac
    35041 tataaaaagt cagaatttga tttagtagtt gaaaaacttt tattgtcaaa tgaacaaatg
    35101 gtagaaagta ttagcgagtt aacttcagtt tatgaacgct tattcaattt tttaattagc
    35161 gaaaggagtg atttaaataa atgaactacc cttatttcaa agtatcagca acagaagatg
    35221 taaaagaaaa attcaataag tgctttgaag taaacaagtc agtatttcaa acaaaatcca
    35281 atatgttccg ttatgttgtt tcaaatttac caatgttaac aaaagccaat caaaatttcc
    35341 gtgatccaga aaaagaagag ttagctaaaa acttagaaga agcaaaatta aaaattagcg
    35401 aacttgaaac gataatagaa ttgcaaaaac agcaacttga aaactttaat aaaaaagaag
    35461 acagtacaca taaagattat agtgaacaat taaatagtat agaagagtct gtctataaac
    35521 tattaattaa tagtggatta gctagtaaag aattagaaga agagcgtgct gaaccagaac
    35581 aagaaagtag tcgtttggga gagggaacaa tgtttagttc accgtcatta agatttacaa
    35641 cggattgaac actaaaaaat tctaatgcaa cttagcatta agtacaaaac cgcctgtaga
    35701 aaaaattttt gaaaatggtg ggtgatgata tgactgaaca tatctttaac agaaaaagtg
    35761 cgagcattat tcttaaagca aaatttgaaa ctggaaaaag caaaaagaat aatcacatgg
    35821 tagaacttca aaaatttgta gattatattt ccagacaaga ggctattagg caagataaac
    35881 tagatcatga ttattcagaa gatgaactaa atgaattagc tagaatagaa aaagctttgg
    35941 aaaaaataga acaggaaaca gatcaaccag tgattaaaga tttacgtgaa atggataaat
    36001 atattgatta tatgacacgt aaaaaagcta tcttagaaaa tgtagataat gaaatagtaa
    36061 acggagcatt tagcaataca aaaagatata tcactaaaaa agacatttca aaaataaaag
    36121 aatcggtcat agaagcaaaa aataatggat cggtgatgtt ccaagatgta atttcattcg
    36181 ataatgattt tttagtaagg gaaggatatt ataatccaga aacaaatgaa ttaaatgaaa
    36241 atgttctata tgaagcaaca aagtctatga tgggaaaaat gcaagaaaag gaagaactag
    36301 ttgatccttt ttggtttgca acgattcaca gaaatactga acatatccat attcatgtaa
    36361 cagctatgga gcgtaaaaat actcgtgaaa taatggaata tgatggtgtt ttacaagcta
    36421 ggggtaagag aaaacagtct acgttagacg atatgatttt taaattcggt agcaaaatat
    36481 tagatagaac gaacgagttt gaaaaaattt ctaagttgag aaaagaagtt cctttagaac
    36541 ttaaacagtc tgtaaaagat tctttgattc aattatatgt agaaaataat tcaagatatg
    36601 acaaagaatt agtaaagtac ctaaaggaat taaaaaaaga aatacctagt acaacacgtg
    36661 gctacaatga gcttcctgaa gaaacaaaag aaaagattga tgaagtcaca aattatatga
    36721 caaaggataa tccaaaaaga aaagaatatg atcgtatgac taaagaaatt gatgagctat
    36781 atcaaacaac ctacggtaaa cgctacaatc cacaagaata ttatttaaat agaaaaaaag
    36841 attttaatgc tcgaatgggt aatgctgtag taggacaaat caaactttta aagcaatctg
    36901 aagaaaaaaa tttgaaaagt aatgaactta aaaatctatt agacggaaaa aaattaaacg
    36961 ttaagtttga tagagaaaaa ccagaattta aaacgaaata tgctaaacaa agttatgatg
    37021 atttccaaaa aagattagaa gaacgacaat tagcacgtga aaaaaatgaa gtccacttca
    37081 agaagatttc tgaaaaattt aaagataaaa agcttattag aaaaattgat agagtaatca
    37141 atgatgattt aaatatgtat cgtgcgaaaa atgattatga agtagcgcaa cgaatgatag
    37201 agcaagagaa aatgagacaa gcacgtgaat ttgaaatagg aatgaattag tagaaacgga
    37261 gaatagaaat tatgaaaaac ttcgatatag tgtgcagtaa tacaaaaaat atatatttac
    37321 gtgagctact taacagtgat tcggaaacta tagaagatgt aaaaaaaatc atagtgttgt
    37381 ttgaaaaaga aaacatggag ctagagaatt gggggctttt tgaaataccg attagtggga
    37441 attactgttt ttataattgg aagacagaag acgatgtagc ttttgcaaat tacttttttg
    37501 ataaaaatta cttttcccca ttatatatag ataagcatag taatgaacaa gttgcttctt
    37561 caataaaaga agcaataaaa ttggaaagag tgaggaaatg atatgatcga ttttagaacg
    37621 gttatggata aactaagtaa tggagatttt cgcgtattga ttgaactata cttaaatgta
    37681 acgtctacag tcaaagagtt tttatattct aatcccaaaa cagctttagt attagttgca
    37741 gtactgatag tttttgctgt gatctctttt attaagaaaa tgattccgct attaattata
    37801 ggtgctgtgt tgatattagg tttgtatttc cctgaagttt tggatcaaat aaaaaatata
    37861 ttttaggctc taaaagcttc cagtagaaaa ttttgggctt tgatatttgt attaagcggt
    37921 ttgaaataga aatttgataa actacatgaa aagacattat ataagagtat ctgtgtattg
    37981 gaataaaaat atgataatat aaaattatat atcagaccga taaaaaagag gtgcttataa
    38041 atgaaaaagt taagagttat tgcaacaata cctatgattt ttagttttgc gctattatta
    38101 tctgcatgtg gcaaagaaga agctggtgct aagtcaaatg aagcacataa tatctcattc
    38161 atagatagtg cagaacaaaa agactcacgt tgttggttgg tagtcgaaac aagtagtaaa
    38221 aataaaacgc ctattgataa aaatgaatat gtaaaagcgg tgatccaaac taaagatggc
    38281 aaagcaaaag tatttaaaac ggatatggaa cagcttacat tggaaaaagt ttctaaaatg
    38341 agtgatgaag aaataataga acaagcattg aacgctgata aacaaaagtt taatgataag
    38401 aaaaaaagcg atattgatag ctataatgcc actttagatt ctgtaaaaac agaattagaa
    38461 aatgaggaaa aacaagagtt tcaaaatgac caaaaaattg ctgattttca agatagtata
    38521 cctaaaatac aggcggatat agaagagatc gatggtgttc aatattcaga gccggagtgg
    38581 aaaatggtat cagcaacaat taaaatggat aatgaaaaca aatcaccttc aatggaaacc
    38641 gttaaattat cttataaata tttagatagt ccaatttgga atttaaatag ttttggtgaa
    38701 gtttcgtctg aaggagaatt atcttatgaa tctactagta tggatttgaa gttatcaatt
    38761 ccagttgcca caacgaaagt tttagataat ttttattcag gatattctaa tgatgaattg
    38821 gatcaacttt tgcttactaa agtagcttct aaagataaca aagttcaatt agatagtaaa
    38881 ggtaaaaacg taagtatagt tgagtagatg gtaaaataag aagggataag atggttacta
    38941 taactatctt atctcttttt tatttgcatt aagtcagtga aattagatag aagagttttt
    39001 atatatctgg tataatttaa ttaggtaatt taacttacct aaaaaagaaa ggagatagaa
    39061 gatggcctat aaaaaaggaa actggaagcc gaaaacgaaa gagcaaaaac aaaaagagct
    39121 agacgattta attaaggctt ccaacagcaa aatcgagcaa tatcagtcta accctgaaga
    39181 tatgatcgag tttgccaagt tcatgtctaa aatacacaat tacagtcctt taaacctatc
    39241 gttgatcgat gagggatttg aaggagcaat tgctgtagca agttatgatg gttggaaaaa
    39301 actaggattt caagttaaag cgaaagaaaa agggataggc atttatgcgc atgctccggt
    39361 aacggttttt attgatgaaa atggtgagga aaagacgtta aaagaagcga caaacgagca
    39421 aaaagaaaaa atcaaaaatg gagaattaag aagcaaaaag atcaagcatt ttaagaaggg
    39481 ttacgtattt gatatttccc aaactaatgc aactgaagct gatttgccaa aaatatttcc
    39541 taacagggta tggaatttta atattgatgg tgaattaagt gttagtcaat tagaaaaagg
    39601 tgtaaatcat ttggccgaat ctatgaatat atctataaaa gatatgaacg agtctggtag
    39661 aggtgaaatg ggaagcgcta gaggtgaata tattcaatat gttgatggta gggaagaaat
    39721 tgtattaaat tcaagaaata gcagaacaca aaatcttact accagtattc acgaattggc
    39781 tcacaaaaag cttcacaata agaatgaaca cggttcttcc tactcaacac cgattaaaga
    39841 gtttcaagcg gaaatgactt catttattgt ttgtcacaat tacggtattg atacgtcaga
    39901 ctttactatt ccttatattg caaattggac taaaaataat gaaaaaattg atccaaaaaa
    39961 ctttagacag ataatgcaag aagttagaga aacgtctatt gactttataa gtacgattga
    40021 taagaaagtc ttggaagaac agcaaacagc atttaatgca ctaaaaaatt cctttgttcc
    40081 taatgagaat aaagagcaga tacaacaaaa atcagattta gaatttcata atttctacga
    40141 tagtacaatc aacgatccgg atagaacaat ccacggtagt tatttagaag cgatggtgga
    40201 ttattataga ggaaagtatg gagaaaattc tattgagctt actcatagca attatgatgt
    40261 tacagctaaa ataggagaaa actatgtgac atattattca gatacgaaac aatttgatgt
    40321 atgtgatgtt tatggtgtag tttttgagaa tccaagtgaa aataaacatg atcgtttact
    40381 attagatcga tcacctgaaa attgtgatta tgttgaaaag tttgttgtag aaagtttgaa
    40441 agcttgcgag aatcatgaac taaaaaatga tacgttaaaa ttaagcgaac cgctaagatc
    40501 agttgttata aatgaagcgg tttataatct atctgaaaat gctaacaatt actataatga
    40561 aaaatgctgg caagaagaaa ttgaaaacca aacaaatatt aatgatgtaa aagaattaaa
    40621 ctcttgtatg actgcggaag atttttacga atctcataaa caagaaatcg aaaatacgat
    40681 tacagatttt gaatctgtgt caggaacaaa tttaagagat acaatagaca atgagtcata
    40741 taaagaggtg gcttcagtgg tagcttataa actggttgca actaaagtaa aatatgaaat
    40801 ggatgaagga actttcaaga taccagaaaa ttctaacttg gaaaagccga ctgtaaaaac
    40861 agcagaacgt tcttttgaaa tggagtgaaa aaattatgag taatgaacaa aattatgaaa
    40921 caggcggaac ttatcgcctg tttcatggaa gtatgaataa atttgatgaa tttagtttag
    40981 atcataaagg tttaaacgga acagctaatg gatttggtgt gtacttaaca cctaataaag
    41041 aaatggctac aatgtacgct gaacagggta gtaacggaaa taatggtttc gtatatgaag
    41101 taaatgttga attagagaag ccgatttcta tgaatgaacg cactattact gatgaagagc
    41161 tttctaaagt aatagataaa ttacaagaaa gtaatgatat tttaaatgat tacaatgatg
    41221 ttagttatta cggagaaaaa gttgtaaaaa gagaagtgat tgcttctctt agtgagaatg
    41281 aaaatgacgt agatttgatt aacgacattg gaaatacaat tggagatcat gaagctactg
    41341 ctaaggcatt ttatgacgtt gggaaatata cacatattat tgcggaagaa cagttaagac
    41401 aaaaggatgt agttatcgta gtgttacagc ctgataaagt aaagattgaa actattcacg
    41461 atttaaacga ggaacggaat agcttagaaa gtagtgagga catgacagat aaatttgttg
    41521 ggcataaggt ttcggaagtt cccattcgag aagttgtgat aaaagatttt gagcaagagc
    41581 tagaaacaac taattattat gacaaacaag cttggcaaga gcgcattgaa tacttagaaa
    41641 acatggaaga accagtttcc agattagcat tagatagtga tattaatgaa ttttatgata
    41701 gtcataaaga agaaattgaa acgaaattga caaatttatc cgaaaagtta gagatcgata
    41761 aagaagaact gctaggtttt ccagtagata cttcttctac ggaatacaaa aaagctacgt
    41821 ctatcatggc ttacaacggt gcaatgagag aaatttataa tgaaattgaa aatgatacgt
    41881 ttgaaatacc acctgtttct gaagaaatgg agaataagat tttgaaattg actaattttg
    41941 aaaatacaac aaaatttgaa atggagtaga taaatgaatg atagaacaag aaaatagaaa
    42001 ttttttagaa acgcaaggtg aatatcgtca aattaataat agtcattttg taatttgtga
    42061 agatgtacaa atcgctttta aaatggcttt gaagtacgga aaaagtatta gaaaaaagat
    42121 aattagagaa aaaaagagca agaagatagg cttttgggag ttatctctta gggatgggct
    42181 aaactttatt ttctgtacag aggattatta tgaaaaatac aagtgtacct tatcgtaatt
    42241 ttactagtga tggtctagta aagggggttt ttgtttggat ttgaaaaagg caaaaaaagt
    42301 aagtatcgtt gatttttgca aacaaaatgg gataggttta aagcaagatt caagggaata
    42361 ctatagatta gaagatcatg attcttgtgt aatcagtgat cgtaaaaacc tttttaaatg
    42421 gaactcaaag gatttagggg gagatatttt tgattttatc aaagcctact acgattgttc
    42481 atttaaagaa gcaaaacaga aacttgaaga tagtgattat gaagttcatt cgttcaatac
    42541 aaaagtgaaa aaagctccgt accaatatca gaaagaaaat gaagtgccgg tatctgttgc
    42601 aaagtcttat ttagtaaatg agagaagaat cgatacagct ttagtggaag attttttatc
    42661 taaaggacta attaaacaag ataaaaaagg aaatgttttg ttcttatgga aaaaagatca
    42721 agaaatcgtt gggtgtacgg aacaaggaac tagaaaattt tttcatgaag gcaaacaaaa
    42781 ggatgttaca tggaaaaaaa tacaagaaaa ctctaaagag tattcaggat ttaacgtaac
    42841 ttttggtcaa ccagataaaa tgtatttttt tgaaagtgaa atagatttga tgtcgtacat
    42901 tacacaaaag ccagaaaaag ccgaaaatgc tacgtttgtt agcatgaatg gattaaaggt
    42961 aggtaatgta ttgtatgggg ttacagagca ttataataag tttaaatcat tgccttcaga
    43021 aacagtcctt tgtgttgata atgataaagc cggacgtact tttattgaaa ctgaatttaa
    43081 agaaaaagga attggaagag aagggatagg aatcagtgaa gtaaaagtcg atgtaccttt
    43141 gcgagaggga tttgattgga atgataattt aacaagagga aaagaagctt ttaaacgctt
    43201 caagttagaa gatgtatcaa aaatcgtgaa cttcacacat aaattatctc ttaatactcc
    43261 tgtatatgaa atggaataaa aagaagaaag tagttgatgt gttatgaacg atacaatagc
    43321 aatcttatca gattcattaa ttgatttaga taagacgtct acagactata tgattattga
    43381 agaacaactt aaaaataaaa atccagagtt cgatattcaa gaaaaatcat tgcgtattga
    43441 attaccaaaa tttaaacaaa aaaaattaat aactattctc tttgagatta ttgaacgata
    43501 tgggcttact tattatcaaa tttggacgga taagaaagat ggccaatata caaaaggggt
    43561 aagcatagaa gccgttagag aagacgatca agtaagtatt aaagcagttc aacccttaat
    43621 ggggtataac gaagaattat tgaattgttt aaacgtctag tgtaaactag gcgttttttt
    43681 acattatttg gctacgaata gacagttaat taaactaaag aaaaccattg actacaagta
    43741 gtcattcctg tatgatatag ccatagacta caagtagtca aagactcaaa cccttgattt
    43801 aataaaaagg agagataata gatggagcag acaagaatgt tttggtcaga tcgaatgcaa
    43861 gatcacttgg attgtattta caaaaccaga gagcaattaa ataagttaga tactgtcaga
    43921 tattatttta cctacttcag tgagaatgac gaacaaagat gggatatttt tcatgatggt
    43981 aattacgaag aattttttta cactgaaagt taattatttg ttgaaatgat gaaggattct
    44041 atttgatgaa agggaacgga aaaccgttcc cctaaaaaat atccaaatga ctacaagtag
    44101 tcatggaagg agagcggaat aatggtaaat aaaaaagaaa cgtttaaagt aggtatggaa
    44161 gtacagggcg ttgttattgg gagcggagag cttatcgagg gagaagtaat tagtttgtta
    44221 gctaatgtag cggtagttaa agcaatcgga aaagcaccgg tagtgatgaa aaaatgcagc
    44281 atgatgtgtc ttgatggttt aaacaatcca ataactcaac gctttgagaa cgtgatataa
    44341 tagaaaaaag aagattttct actgggagag attattatga aagactatgc ttcacgtaaa
    44401 tttatccact tagagcctat gaaagaattg gttattaatg ggaatgaata taatgattac
    44461 aaatctttat ttgtaaagga acagcctaaa ggcggtattc ggatgaaaaa tttaccggac
    44521 ttccgattta tcgaagtaaa caatttagga attatagaag actatttaga taagttagat
    44581 gaagcgataa agcaatcaat tgaaaaaaat ggtgaagatc atatacttac ggttgtttta
    44641 aaagacttga aagatagact agaagctgaa gcagagtact ttaataaaga ctaataagaa
    44701 gggaatgaga gctatgacag aggctgtaaa agaattaaag aaaatgtatc ctgatgtttt
    44761 gaatatgact gtagatgatt ttcatgaagc cttaaaaaat gcagaaagtg aggaagaaag
    44821 gactttctac cttacacttt ctagttttgt gacacgagta gatcaaaaaa aagtaattaa
    44881 tcagaaagac tttaaaatat gagtttagaa aatgaaaaac cgtattatgt agttgttggg
    44941 ggcgttaacg gcgccggtaa gtctactatt tatcaagttc aaaatttaaa aagaaaagaa
    45001 cttgatactg atagaattaa tgcagatgaa attttgagaa gttttggcgg aaattggaaa
    45061 aaacaagcag acataaacaa aagtatgcgt gaagttctaa gagagatcaa aggtcatttt
    45121 aaagaaggaa aatcttttca ccatgaaacg acttttggtg gtaatccata tcccgataaa
    45181 atgagacttc taaaggctaa aaaattaggt tatgaatcgt ttttaatcta tataggacta
    45241 gattcaccag aaagagcgat tgaaagggtt aaaatccgtg ttgctaaagg tggccacggt
    45301 gtacctgaag atttaataag aaaaagatac gaattttctt taagaaactt agcagagtta
    45361 gagaaatatt ttgataatgt aagtatctat gataattcag atgagttttc ttatatttat
    45421 gttaaagaaa atcatacagt tgtagccaat aatacgcaag aatatgcttg ggttcccaaa
    45481 gctattcaag agaaaaatgc tgaaactcct ataagcaaac aaattatgat ggatatatct
    45541 caagaagaga tgaatccaaa agaaaccctt gaaagaatat attcagcaag tgatgatttt
    45601 attagtgatc ggttttcaaa agaagcgcaa gtcgatgatt tttataggaa ccataaaaat
    45661 gaaatcaagg aacggattct atcaattagt ttttctacag gggtatctca agatgaatta
    45721 gtaggtcaag ataaaagaag aaattcttgt aaattggcat atattaatag tgtaggtgag
    45781 cttttagtaa aaactgatag tgagctatta agtatggaat taaatagaga tagaaatatc
    45841 caaaaaactg attttgaagt tgaataaaag aagttgtagc tgaatcaatt aatagtaaat
    45901 aaatttaata aggagtgcga aagcacttct tattttttgg ataaagtgac tatatgtagt
    45961 cagaaggaat aatatattat ttttagtttt tgtttttaat ataattacta caagtagaca
    46021 attgatcatt gattatagtc taggaaatat gttactatta ttatatacca gatatataat
    46081 aatgaggtgc taaaattgac aataataact atgactaaaa aaatagaagt atatgttgat
    46141 ggatcacaag aggaaagaga ttcgtttttt ggtttttttt ggaaaaatag tagagaatat
    46201 gtaaaagcgc tgaatatggt atataaacag ctgatgtttg aagaattgat cgaaaattct
    46261 ataaaagaat tggatcatga gtatattaaa agagagctaa gtcttgaaga gcgaattgat
    46321 aatttactaa gtaatgaagt gatcgatcaa aagaaattag ataaaacgaa aagggaatta
    46381 tctaaactac gaattgcgaa aaacaaagaa gccagagacg ttttgacaca agctataggt
    46441 ttaaaaagtc aaaccagaat acgtgatata gcaaaaaaat tggactttga ttattcggat
    46501 tttatagatt cagctaaaat gaaagctagt aaggatttta gcaatgattt tgttggaatt
    46561 gttactgggc aaagaacacc tagaatctat agaaataaaa ataaatatgg attgttaccg
    46621 ttcagaggtc gggatattaa gattcacaaa gctgacaagt tttatatctc tttacctaaa
    46681 ggatttaggt ttaaagtaaa tttaggtaga aaaccaagaa aagccagaga tagcgcttta
    46741 actttagaac gcattatgga cggtcaatac aagttaaacc agagtaatct aatctttgag
    46801 gggaaaaatt tatttttgaa tttaacaatt tcttttgaaa aagattatca taagctagat
    46861 ttcaaagaag gagctgaatt aaccataaag tttactgatt tgtgtagcgg taaatgttta
    46921 gttaacaatc aatctgtgat tgattttggt gacagcaaat atataagtaa cttcaaaaat
    46981 aaaattaaag caatgaaatc aagggagcaa agccgaggag ttttttctaa aggcggtcat
    47041 ggtcgaaaaa gaaaattaga tcaagataga tgggaagcca taaagaaaag agaaagcaat
    47101 tttgttaaaa cctataataa tcaatgttcg gcaaaaatta ttcaaacagc tatccgcaat
    47161 aagacgcaaa taatctgtat ttctgaacca gataaaaatt atggggaatg ggcttattat
    47221 cagttgaaag aacaaataat aaataaaggg aaaagatatg gaatagaagt taaaagtgag
    47281 tagaataaga aatcgttgat ttggcaacga aatagtgagg ggacactcac tcactgaagg
    47341 gttagctctg tcaagttgtg taaccagacg gaaggacgaa tattgttgag gttttagaat
    47401 catgtaaaac aacacagttc tcaaatgtta cggataaacc gtttgcggga aatcaggttt
    47461 taaaaccatg taaaacaaca cagttctcaa ataaggcttt attgaattga tcagtagttt
    47521 ctgttttaga gttatataaa acgacatggc tcttaaatag gagctaacga agaaaaagaa
    47581 ggtactccgt tttggagtta agtagaaata aaaaaataga atcgttgatt tggcaacgag
    47641 ttgaaaaata cgcaaaacta tggtcaccaa gggataaccc tgaaactgat gatcgctata
    47701 tcttactagt agttaaacag tctaaatagt actcatttat tgtattgatt ctaagggaac
    47761 ctgcaataaa tgagtactat tttactttta attccgctat ctatgtcatt aggcaactaa
    47821 attgttatta atatatttac gtttactcgt atatttttag taacgcatct gtcaaaactt
    47881 tagaaaaatt tattttatct ttttcccctc tagctactaa ccattctggg actgtgacgt
    47941 ttttgcgtac ggtctttttt tggataaatg gagaaggatc actttgaata agagaaacaa
    48001 ttttgttatt gcccaaatta tttagttgat gaatatctgt tggagaagga actgaaatat
    48061 cttcatcaat atagtaagct agaatcccat caagaaattc tttagcattg gacatagctt
    48121 cttcaaaatt atctccttgt gttgctccag caaaatcagg aaaaactact gagtagccat
    48181 tttcttcagc agaaaaaatt acagggtaac tttttttcat ttccaccact cctttcgagt
    48241 taatccaatg aactaaagga ctgggctatt tcagccctaa gtcctttagt aacttctgct
    48301 ctgtcccttt ttttaaatcc tgattactat gaacaggaat aggaacgggt gggaatcctt
    48361 ctttggctac aatatgatgg ctgccagtta tcctcaccac tttccaacca tttttcttgg
    48421 ctagtttgag cattttttta ccggtaagtg gcattcgcga ctacctcctt acaaatatta
    48481 ttatacgcat tatgcgtata aaggtcaaga gtttttacat taaaagtaga atgtaagtgt
    48541 cacaataggg tataccctat tgtatcatat ggtaaaatac agtataataa ggtttggagg
    48601 tgtaacacta gggtgtaaca caatgtgaaa tttggaggtc attttttgaa caagaaacag
    48661 gatcaagaat attatataga aaaattggag aaagagaact tagaactcaa agagcgaata
    48721 agatactatg aaaccaaatt ctgtaaaaga ggtgattgta tgaaaccaaa tcctgttgaa
    48781 acaggtaaaa gaattaaatc aattcgttct aattttggaa tgactatgga acaatttgca
    48841 gatttaattg gaaatgctca aaaaggaaat attaataatt gggaacgagg attctccctt
    48901 cccaacaaag aaagattaat taaaattgct gaattaagta acaaaactat cgactggatt
    48961 aaatggggaa ctttagaaga atatataact tcatacctta tcggtatagg atatgagcta
    49021 tatattaaag actttccaga gatacctcac aaagtcttta aagacattca agaaaaatat
    49081 agtgatacgt tttcgttaga taaagactat gaattattgg attctataat aaaaaatata
    49141 tttacaaaat attactcaaa cggttgaatt gatagatgga ctcaaagaag aaaattcaaa
    49201 gttaaaagag aagataaaat actatgaatg tttatttgat ggtatagaga gtctgctgaa
    49261 ctcacgaaaa aatccctagt ttttatgaat gaccgttttg taaatctgat tgaaatagat
    49321 ttatatgatt tcggtatatg atatacatta ggaggtgtcg aatggaaata aatctttttg
    49381 aggctggtaa tcgaataaag caaatacgag aaaaacatgg atatactatg gcagacttag
    49441 gtaaactggt tgatgccaat agtcctagca caattaacaa ttgggaaaag ggaaataact
    49501 tacctaatag aaagcgtctt gaaaaaattg cactattagg tggtacttct gttgaatgga
    49561 taaagtatgg agatttttcc gattatgttt atcgcttgac acaaaatata gaggaaaaaa
    49621 ttcttaaaga gtacggagag actacactga acaactaccg tgaagctctt ctagatgaac
    49681 ttacgattga aaaaatcaca tacgaagaag atacaaagat attagcagct gccgaaaaaa
    49741 tcaatacaca aaatattttt caggaggtga agtacatgta ttctcctgat gaagattatc
    49801 gaaatataga agtcaaacca gatttaggac tgactgatga caacaaaaat attaaaatga
    49861 ttggacaacg tataaggaaa ataagaaaaa aagagaatat tacattagaa gaattcggca
    49921 aactattctc tcctacagct gataaagctg ttataagcaa ctgggaaaat ggtaaaaacc
    49981 ttcctaactc agaaagaatt aaaaagattg cagaaattgg cggagtttct gaactttatc
    50041 ttatgacggg tgtcgattca agcgtagcag aatcaatgta ttttctatct gaagtagcat
    50101 tggatgcttt ggaacgtctg tcaattgagg aagtcaatag aataattgaa agcttcgccg
    50161 gttatcttaa tgtgatttca aaaattgatg atccagataa gcgagaaata tctctcaatg
    50221 ctatttgtca actatcactt ctcgataaaa tgggttgatt cacaaaaaat attgaaagat
    50281 tactttactc acgaggaggc ttagctatga aacctaatct atcgttaact agtgaacgta
    50341 ttagaaaaat tatcgaatcc aaaggtctga cattagaacg attcggtgat ttaattggcg
    50401 acacaccaat aagttctgtt aataattggc ttagaggcgt gtctttaccc aataaaaata
    50461 ggcttttaac aattgcaaat attggaaaca ctagtgtaga ctggattaaa tggggaactt
    50521 tggaagaata catagcttca taccttatag attcaggtta tgagctatat attaaagact
    50581 ttccagagat accttacaaa gtctttaaag acattcaaga aaaatatagt gatacgtttt
    50641 cactagataa agactatgag ttattgaatc ctataataaa atttactata gggggcgtta
    50701 ctttgaatag aataaaattt tatattgatt ccagtaaaaa gaccattaaa caaattagta
    50761 cagaaactgg tattaactat acaactctta cgaactatta ccgtggtgag cgaaatccta
    50821 gaaatactga aacatggaat atccttgctg attatttcca tgttcctgta agttatttga
    50881 tgggattaga cgaaacaaat gttgaactca aaaaccttaa tattggaaac aacatcaaaa
    50941 atattagaaa aagtaaaaat atgacacaaa ctgattttgc tgagttaatg ggtctatcac
    51001 gatcatatat aggggattta gaaaacaaca ggagtaatcc cagtataaaa acactggaag
    51061 ctattgcaag agcattggac gttccgatag tagcattaat caacgattct tctactgata
    51121 atatagtaga gccgtatgaa agtttgacag ccgaaaatat ccttcttaaa caagaaaatg
    51181 aggaattaaa atatgaggta gaaagcttac gaaaaagatt gtatgaaatc caacaagtag
    51241 taaatcaagg agctgaaaaa atgattccca atctaaaaga cgtaagtaaa agaatcaaat
    51301 atatcagaaa aaaattaggt atgactatgg agcaatttgg ttctcattta agcaactcac
    51361 ctaaaagtac aattgctact tgggaaagtg gtagaaatat accttctcag aaaaagttac
    51421 agctgattgc tatagtagga gaaaccacca ctgactggat taaatgggga actttagaag
    51481 a
//
LOCUS       DBBGSP010000015        50389 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000015 DBBGSP010000000
VERSION     DBBGSP010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 50389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.015"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..434)
                     /locus_tag="ACIZE9_001041"
     CDS             complement(<1..434)
                     /locus_tag="ACIZE9_001041"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGC6092920.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQ"
     gene            680..1627
                     /locus_tag="ACIZE9_001042"
     CDS             680..1627
                     /locus_tag="ACIZE9_001042"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC6092921.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(1838..3910)
                     /locus_tag="ACIZE9_001043"
     CDS             complement(1838..3910)
                     /locus_tag="ACIZE9_001043"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HGC6092922.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(3843..4220)
                     /locus_tag="ACIZE9_001044"
     CDS             complement(3843..4220)
                     /locus_tag="ACIZE9_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGC6092923.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(4349..4909)
                     /locus_tag="ACIZE9_001045"
     CDS             complement(4349..4909)
                     /locus_tag="ACIZE9_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6092924.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            5059..6351
                     /locus_tag="ACIZE9_001046"
     CDS             5059..6351
                     /locus_tag="ACIZE9_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGC6092925.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(6411..7529)
                     /locus_tag="ACIZE9_001047"
     CDS             complement(6411..7529)
                     /locus_tag="ACIZE9_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HGC6092926.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(7543..8964)
                     /gene="arcD"
                     /locus_tag="ACIZE9_001048"
     CDS             complement(7543..8964)
                     /gene="arcD"
                     /locus_tag="ACIZE9_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HGC6092927.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(9210..10331)
                     /gene="mnmA"
                     /locus_tag="ACIZE9_001049"
     CDS             complement(9210..10331)
                     /gene="mnmA"
                     /locus_tag="ACIZE9_001049"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGC6092928.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            10735..11334
                     /locus_tag="ACIZE9_001050"
     CDS             10735..11334
                     /locus_tag="ACIZE9_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC6092929.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(11472..12758)
                     /gene="efmA"
                     /locus_tag="ACIZE9_001051"
     CDS             complement(11472..12758)
                     /gene="efmA"
                     /locus_tag="ACIZE9_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HGC6092930.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(13029..13373)
                     /locus_tag="ACIZE9_001052"
     CDS             complement(13029..13373)
                     /locus_tag="ACIZE9_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGC6092931.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(13510..14655)
                     /locus_tag="ACIZE9_001053"
     CDS             complement(13510..14655)
                     /locus_tag="ACIZE9_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGC6092932.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(14835..15809)
                     /locus_tag="ACIZE9_001054"
     CDS             complement(14835..15809)
                     /locus_tag="ACIZE9_001054"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGC6092933.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(15889..16764)
                     /locus_tag="ACIZE9_001055"
     CDS             complement(15889..16764)
                     /locus_tag="ACIZE9_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HGC6092934.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            16894..18801
                     /locus_tag="ACIZE9_001056"
     CDS             16894..18801
                     /locus_tag="ACIZE9_001056"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HGC6092935.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(19342..22620)
                     /locus_tag="ACIZE9_001057"
     CDS             complement(19342..22620)
                     /locus_tag="ACIZE9_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HGC6092936.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(22891..23436)
                     /locus_tag="ACIZE9_001058"
     CDS             complement(22891..23436)
                     /locus_tag="ACIZE9_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGC6092937.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(23448..24140)
                     /locus_tag="ACIZE9_001059"
     CDS             complement(23448..24140)
                     /locus_tag="ACIZE9_001059"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGC6092938.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(24159..24443)
                     /gene="macP"
                     /locus_tag="ACIZE9_001060"
     CDS             complement(24159..24443)
                     /gene="macP"
                     /locus_tag="ACIZE9_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGC6092939.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(24456..25019)
                     /locus_tag="ACIZE9_001061"
     CDS             complement(24456..25019)
                     /locus_tag="ACIZE9_001061"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGC6092940.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            25247..25909
                     /locus_tag="ACIZE9_001062"
     CDS             25247..25909
                     /locus_tag="ACIZE9_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HGC6092941.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            26033..27229
                     /locus_tag="ACIZE9_001063"
     CDS             26033..27229
                     /locus_tag="ACIZE9_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HGC6092942.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(27330..28706)
                     /locus_tag="ACIZE9_001064"
     CDS             complement(27330..28706)
                     /locus_tag="ACIZE9_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6092943.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(28743..29610)
                     /locus_tag="ACIZE9_001065"
                     /pseudo
     CDS             complement(28743..29610)
                     /locus_tag="ACIZE9_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
     gene            complement(29699..30724)
                     /locus_tag="ACIZE9_001066"
     CDS             complement(29699..30724)
                     /locus_tag="ACIZE9_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC6092944.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(30742..31416)
                     /locus_tag="ACIZE9_001067"
     CDS             complement(30742..31416)
                     /locus_tag="ACIZE9_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6092945.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(31600..32493)
                     /locus_tag="ACIZE9_001068"
     CDS             complement(31600..32493)
                     /locus_tag="ACIZE9_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC6092946.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(32567..34264)
                     /locus_tag="ACIZE9_001069"
     CDS             complement(32567..34264)
                     /locus_tag="ACIZE9_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HGC6092947.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(34257..35570)
                     /locus_tag="ACIZE9_001070"
     CDS             complement(34257..35570)
                     /locus_tag="ACIZE9_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HGC6092948.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(35570..39511)
                     /locus_tag="ACIZE9_001071"
     CDS             complement(35570..39511)
                     /locus_tag="ACIZE9_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC6092949.1"
                     /translation="MEKLDEPIVPSGQALQRIQRQLFNGILERLGPTATQDPYEYIYP
                     SGEVENEQHRYPKFTTNDYTKVLGNWTQSNERYQGDKGSPYDGENLIDDSDYTNGGAN
                     WRNYDYATNNGSTAGEEDRNVPAQTVQLWGNERNFENSYLDYNGAYIKKWVEPVLPSS
                     TASDLHPEDATTLYNVYLDVIGGEKKEISPIDIVFVLDKSASMSELTAGTNSQTKNAA
                     LIEAVNEMSKDLLSDPSLDIRIGMVNFYHNSTAINNHEQISSDIFPLTNDINRLTGSE
                     NTALNRTPIGGTPLTLGLKNGYETLYKDNGGENRNPEKILIVVGDGTPTFSYAPIQSS
                     YRTSTNGAWSNWTVMEDKIAEDNDVLFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDE
                     VNVHYRYGEVKEGDNKATHWVGDGSSNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQE
                     NPPSIFSIGLGIDGNVSGRQRLDAIGRNVLKNIADLEEDGVTPRYYNANNKNDIVTAL
                     EDISSTFKRTIQQATLYDETGFNVSPFGAGRSADIQFYHLDPGENGMKYQEPEIWDEE
                     RHGQAPPEVVATPTTYVGRENQAYKFSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVN
                     NMAYIQNLEDYENDITTGRMYFPSSSIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQ
                     NPESGEAEPIETSKTTTDGIAIFETKMPILGDETGAVSDIFWIREIAGPPRYQLVDET
                     YQFQIKKYAANEDEMLGHYELVDEYTSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNI
                     EGTEYDELYVKLEMRNEFKPIHMNINKLIEGSNMPINGAEFELYETDGNGLEIGYPVA
                     KGLSGVNEVEEEKGRLTFYSVDEDGKYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAE
                     YKIIESQNPEGFKEPDENDTWILRLYDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWV
                     AFTAYNTFDYREIRVRKLDHEGHTLDGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKR
                     LPGIGYFYSRAVGVEKYVDLNYDQPLHLSIGEYEVSESVAPNGYRLSDQVFQFALNEE
                     GKFIIEDTVIEDETAPLPEGYEIIDGVLQVTLEDELAPIDLELLKIDSMNSRRLEGAE
                     FSIEKQNSAGEYEIIEGGLAPDPNDSSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFI
                     LEISYREEPDIENDRVVPGKEAGTLKVEISYYPNEEAETPDLQQELEYELLETNRIRL
                     QLSVGNDPENPLPATGGSGRLFYILLAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(39620..40078)
                     /locus_tag="ACIZE9_001072"
     CDS             complement(39620..40078)
                     /locus_tag="ACIZE9_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC6092950.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(40376..40894)
                     /locus_tag="ACIZE9_001073"
     CDS             complement(40376..40894)
                     /locus_tag="ACIZE9_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGC6092951.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(40896..41513)
                     /locus_tag="ACIZE9_001074"
     CDS             complement(40896..41513)
                     /locus_tag="ACIZE9_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGC6092952.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(41510..42364)
                     /locus_tag="ACIZE9_001075"
     CDS             complement(41510..42364)
                     /locus_tag="ACIZE9_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6092953.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(42361..43272)
                     /locus_tag="ACIZE9_001076"
     CDS             complement(42361..43272)
                     /locus_tag="ACIZE9_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6092954.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(43313..44647)
                     /locus_tag="ACIZE9_001077"
     CDS             complement(43313..44647)
                     /locus_tag="ACIZE9_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6092955.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            44855..45685
                     /locus_tag="ACIZE9_001078"
     CDS             44855..45685
                     /locus_tag="ACIZE9_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HGC6092956.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(45929..46178)
                     /locus_tag="ACIZE9_001079"
                     /pseudo
     CDS             complement(45929..46178)
                     /locus_tag="ACIZE9_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(46369..46563)
                     /locus_tag="ACIZE9_001080"
     CDS             complement(46369..46563)
                     /locus_tag="ACIZE9_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092957.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(47068..47253)
                     /locus_tag="ACIZE9_001081"
     CDS             complement(47068..47253)
                     /locus_tag="ACIZE9_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092958.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(48103..48444)
                     /locus_tag="ACIZE9_001082"
     CDS             complement(48103..48444)
                     /locus_tag="ACIZE9_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGC6092959.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(48444..48674)
                     /locus_tag="ACIZE9_001083"
     CDS             complement(48444..48674)
                     /locus_tag="ACIZE9_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGC6092960.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            48961..49299
                     /locus_tag="ACIZE9_001084"
     CDS             48961..49299
                     /locus_tag="ACIZE9_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092961.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(49504..50066)
                     /locus_tag="ACIZE9_001085"
                     /pseudo
     CDS             complement(49504..50066)
                     /locus_tag="ACIZE9_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
BASE COUNT        14639 a        10699 c         8866 g        16185 t
ORIGIN      
        1 aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt cagttttcca
       61 ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt tcgatttgcc
      121 tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc tttatacgtt
      181 cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg aaaaggcgta
      241 cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa atattcttca
      301 aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc tgaaattggc
      361 tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa gccgataggt
      421 gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc ctttttctct
      481 atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa accgaggaaa
      541 catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac gtaaaatcaa
      601 attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat ataaacatac
      661 gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta atgaagaaaa
      721 aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg agttcgaata
      781 tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga agctagcctc
      841 agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag aagcggctct
      901 gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg ttgatctgca
      961 agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg atatcgattg
     1021 tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt tctttgcgaa
     1081 aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg gcgctcgtga
     1141 tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag aatacaaccg
     1201 attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt cttatgaaaa
     1261 ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca actactcgat
     1321 tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta tcggcgcttt
     1381 gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat tgttgtttgg
     1441 tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg gtggaatcca
     1501 attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag aaacgaaaca
     1561 gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat tgaagcctca
     1621 ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac tgtgacaaaa
     1681 gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt cttcggaaat
     1741 aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
     1801 agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt gctgctttta
     1861 gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt ttcagcaagc
     1921 gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc aatttttctg
     1981 tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg atttccattt
     2041 tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt ctgcggtagt
     2101 tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc tcgcgcagat
     2161 tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat tcttgtttgc
     2221 ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc aagaaggttc
     2281 ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt tctgtcaaat
     2341 ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta ggagatactt
     2401 gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg ataatctctg
     2461 cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag cttgcttctg
     2521 acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga ttgattctca
     2581 ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc catcctgctt
     2641 ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc gtaacttttg
     2701 tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca atcatttgat
     2761 agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca gttggcaaaa
     2821 gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg acgatggctc
     2881 cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc aatcgttctt
     2941 tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga taagtaacga
     3001 tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca gaatagccat
     3061 agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc gcagattccg
     3121 tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc aattgaacaa
     3181 gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc attttggctt
     3241 gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac tgctcgattt
     3301 tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct gctgataaat
     3361 tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc cagtccgctt
     3421 ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt cttagttgct
     3481 tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc ttcactggtt
     3541 tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct cttccggcat
     3601 ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg attgctttta
     3661 attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc attggcaacg
     3721 tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc aatcctaata
     3781 aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt ttgtgctttt
     3841 gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc gctagaatta
     3901 gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt tttcaacaac
     3961 gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg ctcatctccg
     4021 tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata attttgatgg
     4081 atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc gaatgtttct
     4141 tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt gtccccgaac
     4201 atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga ctcatcttag
     4261 tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta atgaacatct
     4321 taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag ttattgatca
     4381 tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat cctaaaaaac
     4441 gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga actttttctt
     4501 ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt tcatggattc
     4561 catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca tacactgctt
     4621 gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct tcctgaccac
     4681 tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt ttcgctgtta
     4741 gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga gccttgatat
     4801 ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct tctgctagtt
     4861 ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt tccatgtttc
     4921 ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag agaaaaaaga
     4981 gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga tgaaaatttt
     5041 cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag gaaaagagaa
     5101 acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg tatcggattt
     5161 agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta tagtacgtca
     5221 caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac tacgcttatc
     5281 tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct gttgcgtgct
     5341 tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt gtatcaatta
     5401 gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc cactgccctt
     5461 gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt agcaactggt
     5521 tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc agcgtttggc
     5581 tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt gttgagtctg
     5641 tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc tgccaaacag
     5701 attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac aacgatgatc
     5761 atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg ccaattgctg
     5821 catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc tgggattgcc
     5881 actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag tgaaagaata
     5941 cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt cgtcacgaat
     6001 gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg tctgctccct
     6061 gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg gatcttcagt
     6121 tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg ctccagtgtt
     6181 tccagtgcat ttggttatcg cggcgtcttt ctttcgactt ctcttcttgt tttggtcaac
     6241 ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc agaagaaaaa
     6301 gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata agcgtaaatg
     6361 aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt ttaggcctgt
     6421 tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt tttacaacag
     6481 taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa tagtactcct
     6541 gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc taatttaatg
     6601 aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt ggctacccat
     6661 tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa tattttttct
     6721 ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca aatcatcgtg
     6781 tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt ccagccaata
     6841 cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc tttttcatag
     6901 acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac ttcatctatc
     6961 aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt tttccgatct
     7021 agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt ttcaggtttg
     7081 actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt caaatgaaca
     7141 aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata agtaggaagc
     7201 atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag attagcacca
     7261 gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag agaagcgact
     7321 tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc gtttttgcgt
     7381 ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc taatgtcaat
     7441 gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt atttagccat
     7501 tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct tgatccagcc
     7561 tacagcaagc aacccgattg aaagcagtgc ggccacacaa atcagcccaa tcattacttt
     7621 ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga agcaaaaacc
     7681 aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa tgatgcccat
     7741 caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc cttcttttaa
     7801 agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg ccgctgtaca
     7861 taaagaatag gcaaattgat aggcataatc agtaactaag aaagtcaata agaatagatt
     7921 agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat tcgtttttcc
     7981 ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg ctgggagcat
     8041 cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga tcagcgctgc
     8101 tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg aaatagttgc
     8161 taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat agataaacaa
     8221 taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct tcgcgcggtt
     8281 ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca tcaaacaacc
     8341 tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat tatcagatac
     8401 gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata caaatattaa
     8461 aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga cgctcgctcc
     8521 ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg caaataaaat
     8581 agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg cgctcatcag
     8641 catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc aaccactgat
     8701 gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac catctagatc
     8761 tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac caatcccaac
     8821 gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat cacttgtgat
     8881 cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc cccatttgct
     8941 aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg aacaaatcac
     9001 ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc aactttattc
     9061 atattattgg atattatgaa ctttttacac aagtatttca agtataaaat gaataaaaat
     9121 taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc ttttgttagc
     9181 catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt tgtttcttga
     9241 tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa tacaactgct
     9301 tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg attatcatcc
     9361 aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc tgtacacttg
     9421 aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc caagcttgtg
     9481 gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt cgctagatct
     9541 tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc tagtccttga
     9601 cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc accatcaaga
     9661 gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt gaagttcttt
     9721 tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag gcctgcgcgt
     9781 tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat cgtttttgaa
     9841 agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt gtctactcca
     9901 cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg tccagtagct
     9961 acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt gatttctttg
    10021 ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag gaaatattca
    10081 aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat cccgatttga
    10141 gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc gttttcgtcc
    10201 gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc ctttaacaaa
    10261 agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg tgttttgctg
    10321 ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac gagttgaagg
    10381 tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca tcccttaatt
    10441 atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat gatagtcaac
    10501 caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc ataaaaaggg
    10561 ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt ttcaaaattg
    10621 cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag atgttatgag
    10681 ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag atacatgaat
    10741 tactttatca gtgatatgca ctttttccat gaacgcttat taggaaaaaa cgactttgct
    10801 ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag ctggaatgca
    10861 gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca tccgcaatat
    10921 gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac aatccacttg
    10981 atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa tgatcctagg
    11041 cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt taaattcgac
    11101 catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga cactatccgc
    11161 aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt caatgtaggc
    11221 gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac tccgttatct
    11281 gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc gtgaaaaaac
    11341 tgccctatat caagtattaa acaaataaag ataattactc atatttttca tttgagtagg
    11401 cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt ctgtcacaac
    11461 tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt tttctgtaat
    11521 tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca taataaaatc
    11581 ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa tggtcctgca
    11641 aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc taagacacga
    11701 cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt attgaaatat
    11761 ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc ttgactatcg
    11821 tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc tataataata
    11881 ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc taagagcatt
    11941 ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc aaagtaatct
    12001 agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac aaatgcacca
    12061 ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc aaattttgca
    12121 tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg gatcttcaca
    12181 aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat aaggtaattg
    12241 acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa attcgctgat
    12301 tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac gattgtcggc
    12361 ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat aaacaaagac
    12421 acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc taaaataagc
    12481 gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc ccagcgatcc
    12541 actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag taaagtagca
    12601 aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat cgcatattgg
    12661 acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa ataatttctc
    12721 ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct tttctttttc
    12781 attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa aaaatacctt
    12841 tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa taaatcagca
    12901 aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt
    12961 cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg tctttttata
    13021 tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc catcagaaaa
    13081 taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac tgctttcaat
    13141 ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac agtgattttt
    13201 aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg
    13261 cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc atcaggatgc
    13321 aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc catgattttc
    13381 acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt actaggtttt
    13441 tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat ataagaatga
    13501 cttcactagt tattttttga cagcacgaac taattgatca aggaaatact ggatgtcgtc
    13561 ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg gtgtatcttc
    13621 tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac aagctgaacc
    13681 agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat ttgcttcgcc
    13741 aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat ttacttgata
    13801 agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt tatatttgtt
    13861 gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca taccccagat
    13921 ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa
    13981 tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg gcccattgat
    14041 tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga tcgtttggtt
    14101 tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta aaagttcacc
    14161 gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca cagagaccaa
    14221 gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc ctttttcatc
    14281 tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg tattaagaac
    14341 agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac gcgagaacgc
    14401 tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga tgatctcgtg
    14461 aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc
    14521 gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca tgattgccgt
    14581 catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca gataaatagt
    14641 tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata aaatagcgaa
    14701 caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag aaaaaaggag
    14761 ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac aacttctttc
    14821 cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg actcatcggt
    14881 gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt aacgattgtt
    14941 aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca aatatctttg
    15001 attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg tgacgcacag
    15061 gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc aagcgttgct
    15121 cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc accgatcaca
    15181 taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt gctgttcaaa
    15241 tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac aactacgatg
    15301 tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat cgtaaataaa
    15361 ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc taaagtcagt
    15421 actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt gatcggttca
    15481 tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac gacattgatc
    15541 gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat atagtaatca
    15601 ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat actttcttcg
    15661 atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc taattctgtt
    15721 ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact aaaaatcttc
    15781 aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct ctattcttcg
    15841 atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt aaggaagtga
    15901 aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc agttgtcgtg
    15961 tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg
    16021 attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt tgccttcacg
    16081 tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac gctcatgatt
    16141 gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag
    16201 tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt
    16261 tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat aataggcaag
    16321 gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc atttcttata
    16381 cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct ttcctgacct
    16441 tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag ataactcgat
    16501 tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat aagtatattt
    16561 tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac tttgatcttc
    16621 aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct gagtgctggc
    16681 taatttttta atttttttat ctactttgaa atataaaggt ttatccacta cttgattcag
    16741 ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa atcagtttga
    16801 ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt gtaagataat
    16861 gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt gaaacaagat
    16921 ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc agataaacca
    16981 gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat gggagaaaca
    17041 gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca
    17101 tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca accgcttcaa
    17161 cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa gcaatttcca
    17221 gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc agatatgaag
    17281 aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc agataagacg
    17341 tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt tgatatggct
    17401 gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa
    17461 gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga aaacgcagat
    17521 tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac agataaactg
    17581 gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt gatcgtaact
    17641 gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt tccgttattc
    17701 aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc agaagaattc
    17761 cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag
    17821 aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg cgattactac
    17881 ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg
    17941 atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc aacaaaagaa
    18001 aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga taagatccca
    18061 gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt gctttcaaat
    18121 actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa caaaccagtg
    18181 gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca tccatttcgg
    18241 aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct agaacaatca
    18301 agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc ccatgcattt
    18361 gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg gacagaagaa
    18421 gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga tggtctgcct
    18481 tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc tgatgcaggc
    18541 ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat cgaggaattc
    18601 tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca acaactttta
    18661 ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt
    18721 gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct agcgccagaa
    18781 aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa
    18841 ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt ttcgaagaag
    18901 ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt caagtagtaa
    18961 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta ctaccgagaa
    19021 actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt
    19081 agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    19141 gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct gcatcaagta
    19201 ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga tagaaggaag
    19261 tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa ttgttttaca
    19321 tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa caactacacc
    19381 gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc ccgtttttgg
    19441 gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat gagaaggttt
    19501 tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    19561 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    19621 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    19681 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    19741 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    19801 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    19861 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    19921 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagacgg
    19981 tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    20041 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    20101 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    20161 atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    20221 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    20281 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    20341 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    20401 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    20461 actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga atccattacc
    20521 gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg agtttttgat
    20581 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    20641 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    20701 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    20761 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    20821 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    20881 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    20941 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    21001 tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa cgccttttgg
    21061 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    21121 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    21181 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    21241 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    21301 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    21361 atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca cctctcctgt
    21421 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    21481 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    21541 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    21601 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    21661 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    21721 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    21781 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    21841 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    21901 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    21961 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    22021 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    22081 aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    22141 cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg
    22201 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    22261 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    22321 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    22381 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    22441 ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    22501 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    22561 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    22621 gtgtattcct cccgtaacaa attagaaagc gtttacttaa agtattacct aatttatttt
    22681 tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa aaatataact
    22741 taagttgttg ataataaaga gatttattaa cgtaaaaaga ataagttttt ttaaaataac
    22801 gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc tcttctttta ttattttgtg
    22861 ctttttattt tatcaaatca ctttgttttt ttataaaatt tctgcgccta gtgtggactc
    22921 aaaatgtctc aatgcccatt catgtccaac gggatcgaaa cttgccacgg aatctttgaa
    22981 aatatggagt ttgtatccta gattatacgc atcgactgct gtatgcaaca cacagatatc
    23041 tgtacatacg ccggtcaaat aaatatctgt gatctggcgt tctcgcaaac ggatgtctag
    23101 atctgttcca ctaaaagcgg aataatgccg tttgtctatc caataaacat tttcctcttg
    23161 ctcatagtct tggtataaac tttttaaaga gccgtacaat tcccgtccac ccgttcctat
    23221 cacattatgc ggaggaaata agcggttctc cggatgaaag gaatcttttg gatcatgcgc
    23281 atcaatggca aaaacgacaa aatccttttg atcaataaac ttctttgtat gagcagtcag
    23341 ctttttttca attacttgtc ctgctgtccc agtagtcagc tttccatcct ctgcaacaaa
    23401 atcatatgtg tagtcaatcg agatcaatgc gttcatctta gtcctcctta tacgagatgt
    23461 ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg cgtcttcgat aaattcgtca
    23521 aagctttgtg tcgccgagtg atctgctgtg tcgctcattg cacgtacgat caaaaatggg
    23581 atattgaact gacgagctgt ttgtccaaca gcggctcctt ccatttcgca agctaatgct
    23641 tcagggaaat tcgttaagat ttctttgatt ttatctggcg agtcgacaaa tgtatcacct
    23701 gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt ttgctgcttt aaccatttca
    23761 ctgcgcaaat atgtgcttgc ttcataatat agaggcattc ctggtaattg tcctgggttg
    23821 tagccaaatc ctgttgcatc tgcatcaaaa taagctactt tgtctgatat aacgatgtca
    23881 cctacttgta agccttcacc gattccgcca gctgaacctg tattgatcac catgttcacg
    23941 ccgtattgtt ggatcaacag acttgtggta atagatgcta agacttttcc tataccggaa
    24001 cgtacgacga tcacttcgtg gttacctaat gaacctgaaa taaataaagc gcctgcgcgt
    24061 tcccatgata atggttcgct taggttctct ctcaaaattt ttacttcttc ttccattgcg
    24121 ccgataatac cgattttcat ctttttaatt ccttctttct atataaatgc gattgctaaa
    24181 aaaaccacac ataacattag gataacaata ataagagatt tcatcaaaaa agagttccat
    24241 ttggtcgtct tttcccgttc gctgatcctt gttttcgtga ttggtttatt ctttttgctt
    24301 tctttacgat aaaagctggc aatctttttt tcttcttgct gataagctgt ttctgctttt
    24361 cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc gcttgcgaag ttcgcttcgc
    24421 gtaataagcg gtcctttggc cataagccga tccctctact ttcctttggt caatagttcc
    24481 cagtattgaa tcgcataaat cgtctttgca tcacaaatca actgatcttt catcgcttgt
    24541 tgcgcctctt caagagttag atgatacaac tccagtactt cgtcttcatc ttgtgctaaa
    24601 ggattctcga ccttctctac cccttgtgca tgataaatat gaaggacttc atttgcaaaa
    24661 cctggtgaaa gatacatcga agtaagatgg ctcagcgact tcgcacgata gccagtttct
    24721 tcttctaatt ctctagctgc tgtcatttcg ggattttgtc cttctcctgg atcgattttt
    24781 ccagctggaa tctccaaaat cactttttct aaaggttttc gaaattgttt gacaagaagc
    24841 agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc caggatgaaa taccagttct
    24901 ctcttcgaag ttcctccatc tggcaaacga acttcgtcta cagcaacatc aataattttt
    24961 ccgctataga tttctttgcg actgattgtt ttttcttcaa attgctcatt gttcagcata
    25021 tcttctcctg ctttctttgt aatcataact gctttttttt catttttcaa tttttctcaa
    25081 aaactcctta ttagtttacc atagataaac cttagatttt ctctaaatat agaaaatcct
    25141 tctttagtcc gatactcttt ctagtagtcc gtatgctaaa ataagtatgt aatcgaataa
    25201 cgaaaagaat tcaatactca acgataaatg acatggaggg tttattatga taaaacgaaa
    25261 ttggccgtgg cttctagcat tggtcttgct atttctcttt gtccgaaaca atagtttttc
    25321 ttttgttcta ggacttttat tgataggtgt agttttagtt ttgtggggac tctttggttc
    25381 gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg actgacgaac ttgaaactca
    25441 ctatgaaaaa agcggtatga cagcgaatga aatttcattt tttcgacaaa caatgaatca
    25501 aacaaaaaat gagatcaatc aattgcaaat gaatatgcag cagacagcca aacttaaagc
    25561 aatcgatctc cgccatgatc cagtcaaagc agcgaaagct ttattcaaag aattggtgaa
    25621 agaaccaaac cgactgcatg aagcaagtca gtttctttat acgcatctgc cgaatctagt
    25681 tgatttgaca aataagtata atgagatcaa tgaccatgag atcaaaaaca aacagaccta
    25741 tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg tcagctttaa tcgcacaaga
    25801 ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac gtagagatat ctgttgcgaa
    25861 acagagctta aagcgtgata ataaatatga accagaacaa aaggattaac tcttttgttc
    25921 ataaaagaag actcggaaca ttcagatgat gtctggctgt ttcgagtact ttttctaaag
    25981 tagagacatt catgtaagaa tcgagaacag attcaacaag gaggaatttt ttatggatca
    26041 taaaccgact gaaacaaaag atgttacacc agttaacgat acacttgaag atttattgaa
    26101 caacccgttt tcaactccaa cagatacgct gaccacttca caacaagcgg agattgatca
    26161 gctccaagag caacagacag ctgctcgttt aattgacaaa ctaccggcgg aacgccaaga
    26221 acaagctaaa cagctagcag caaaaatcga tgctaatgat gcacagtctg tcatcagcta
    26281 cggatcggct gcccaagcaa aattaagtga attctcacaa tcgatgttga atcatgtgca
    26341 agcacaagat attggtcctg taggagattc cttaactgaa ctgatgtatc gtctccaaga
    26401 agccaatcct gacgaactgc gtgccggaga agggaacatc ttccagcgtg tcttcgggaa
    26461 ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa aagattggtg cacaaattga
    26521 caagatttca gtgaaattag ataaagaaaa agacggtctg ctaaaagata atctgatgtt
    26581 agaacagctt taccagaaaa acaaagacta ctttgatgca ctgaatattt atatcgctgc
    26641 tggagaattg aaaatggaag aacttcaaac aacgatcatt ccagaagcga tgaaaagagc
    26701 agaagaaact ggcgatcaga tggatgttca gattgccaat gattacacgc aattcctaga
    26761 tcgtctggat aaacgtacgc atgatcttcg cttagctaga cagatcacga tccagcaagc
    26821 accacaaatc cgtttgatcc aaaacacaaa tcaggccttg gctgaaaaga tccaagcatc
    26881 tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg atcgcattga ccttgcttcg
    26941 tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa acaacaaacg acttattgaa
    27001 gaaaaattca gaaatgctga aaatctcagc catcgaaaca gcgaaagaaa atgaacgtgg
    27061 aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat ttgatcgaaa caatccaaga
    27121 gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt catgcagaag tagagcttgg
    27181 acacatggaa gaagatctga aacaaaaact gttggattta acccaataga tcacctttcg
    27241 cttgttacta aaacaaacgc ccaacaacag tttattacaa ctgttgatgg gcgtttttct
    27301 tatctttctt ctaacttctc cattggagtc tatttctcat tcatcttgct gtgtccatag
    27361 ccatagccaa aataaatgat cagtccaata accattacga taccgaacac gatccatgtc
    27421 acagtttgca gacgaagcat caatacaata caagtcaaaa tggagacgat tggcaatagc
    27481 ggaacgaatg gcactttgaa ttctccagct tttggtttgc caaacatttt tctcaacttc
    27541 agtaagccta gactaacaag catcaaatag gcgagcgcca tgatattcgt tagttccgct
    27601 aatacattca atgggaaaaa tccggcaaag aatacagctg ccacaccagc ggcataagtc
    27661 gcttttttcg gtgtacgatg cttttgatcg atttctgtca taaacttagg aagtaagcca
    27721 tccttgctga cagcaaacag taaacgagca agtgaataca tcatcgagat cgttaccgtc
    27781 agtagcgtta aaattgcccc tacagcgatc accgcgccca ctgttccatg tcctacatac
    27841 ctcattgcaa aagccactgg gtcattgact cctagttcag tatacggaac gattcctgtc
    27901 aagatcagcg tcacgatgat gtaaaggaca gtagcaatca gtatcgaacc aatgattcct
    27961 cttggcacat ctttttgcgg gtttttgact tcctcggctg ccattgcaac ggcatcaaat
    28021 cccaagaaag caaaaaacac aagagctgca ccatctagca caccggaaaa accaaaaggc
    28081 atgaatggct gccagttatc aggtttaacg aaaaatattc ctacaatgat aaacaacgcg
    28141 atgataccaa atttgacata taccatggca ttattcaaac gtaatgcttt cttggcttca
    28201 agcgacacga tgtaagtgac gaatatcact acgagcaccg caatcaagtc aatgtatgta
    28261 ccattttccg gattgtaccc gccagttaat gcttgtggaa gttcggcccc taaacttttc
    28321 aaaaaacctt gcatatagcc agaccatccg gaagcaacag aggaaaccgc tagtaaaaat
    28381 tccccgatca acaaccaccc tgtcagccag gcagcaaatt caccaaatac aacatacaga
    28441 taggcatatg gcccaccaat cactggcact cgcgaagcaa attctgcgaa acttagtcca
    28501 gacaaaatga caacgattgc agctaagaca aatgaaagtg acagtgctgg accagcattt
    28561 tgattggccg caacccctgt caccacaaat attcccgtac cgatgatcgc accaattcca
    28621 agcatgatca aatcagacgt ttttagttct tttttcatct cactcgtatg attgagattg
    28681 atctctttct tacgaaacaa atccattgaa gttcctcccc attttaggtt ggaaaacagc
    28741 gattaaactg ttttcatata ccctaaaagg gataccacct aaaatgacta aaaggcaacc
    28801 aacaataaca taaatgagct cttttttcgt ttttctttcg ccaaggatga aaatcccacc
    28861 taaagtagag ataatgatcc ccatttgtga aagtgagaag ccaacagcta aaccaagtga
    28921 tttgactgtt agaagcatgc agatgtttcc taagccccat aataatccac agatcatgtt
    28981 tttccacaca aactgatcga ctttaacttt acggaaagca aagaagcttg cgcctaagat
    29041 cattccgata ctttgaggta agataattga catcgcatcc aaattcgccc agttgacgat
    29101 gatggtatat acaccataac caatcgtaga gaagatcaat gctctaaaac ccttaccaaa
    29161 atcaagcatt ttattatctg tatctatttt tccttcgtca tcttgtcggg cagtcaaata
    29221 cgcaccgctt acaagaagag ctaaagcaat aataccgtat acataatctt tcgtttgtgt
    29281 ccattcatgg aagaaaacgg ctcccgcaat cgtattcaaa attaattgaa aaccagtaga
    29341 caatggtagc cctacagaaa cacccatgta cttcattcca tggaactgtc cattttgtcc
    29401 aacactccaa gctaagccgg ataaaaatcc gatcaagaaa atccaagggg tgattacagg
    29461 actaacaacg aaaaagacaa ctaaagaaaa cagaaatgca ccgatcgtca ttcctagtgt
    29521 ttgttgattg gcatcgccac caattttacc acttactaaa ccaatactac cccatgccaa
    29581 catagggact aatgctatta aaatttccat aaccaatctc cttttatttc acatgataag
    29641 aaacttatca gcgaaaacgt taacaacaca agcacttttt ttcgtttcta acgattttct
    29701 aacgtttttc attataaaaa tttaagattg ggaaaaataa agtcattgtt gtcccttttc
    29761 cttcagttga ttcagccgtc aaatggatac ctaatttttc ggccagattt tttgctaaat
    29821 aaagtcctaa tcctgttgaa tgtgttttgc taagtcgacc atttctccca gtaaatccct
    29881 tatcaaagat ccgtttcaag tcttccgctg ggataccgat ccctgaatct ttaactgaaa
    29941 ggctgactcc ttgcgcttcc ttttctatgc tcacaatgat gtttccgtga tccggcgtat
    30001 atttgatggc attactaagc aattggttga agataaaagc gatccattta gcatcggtca
    30061 aaacagtatg atcctcacca acgatctcgt agcgaatatt tttttggata aaataatttg
    30121 cctgactgcg tatcacaggc tgaatgattc cttttagtcc atattcttgg atgaggtagt
    30181 cccgcgagaa actgtcgagt cttgcataat acaaaacttg ttctacgtat tcatcgattt
    30241 ttgataattc attttctagt aatgtatact tttgatcgtc aatatcgaac tcgatcgaac
    30301 gaactagcaa tttagaagcg gaaagtggca ctttgatttc atggacccat gagtcaatat
    30361 aatctttttg gtcttgttga ttactgattg ctgattgcat tacttcttgg tgttcacgga
    30421 tcagctgatt gatatattct tctaccagtt tttcttcttc tgtcctccca ccactcaaat
    30481 aattttgcaa aggggaagtt ttttgtatgt cggctaattt tccccaccat cttctcttgc
    30541 tcaagtaacc acccagcaga taaaaaatca gaaagacgcc ctcaatcaaa gctaaataag
    30601 caattgtgct caaatcaact ttgatgtttg gcgccagcca catcacaaag atcgtcaatg
    30661 caataaaaaa cagccatccc aagatcaatg tccactgatc tttcaaatat ttaaaaaaat
    30721 tcatcttaac cgctcatcct ttcagggaac gatatatccc tgtcctactt ttgtttcgat
    30781 atatccttgg atacctgcct gttcgatttt tcggcgtaac cgattgatgt tgactgtcaa
    30841 tgtattgtca tctacaaatc gttcgtcatc ccacagtgct cgcagcaatt tttcccgact
    30901 taagatcttt ccattgtgct tcatcaaaat aaataataga cgatattcat ttttgctcaa
    30961 atcaatgatc tctccgttga tttccatact tccgttgtca acattcaacg taatgccatt
    31021 gtggctcatc atttcactag ataattctgt gtagttgtaa gaacggcgaa gtaatgcatt
    31081 gatttttgca atcagtacat cgatttggaa atgttttgtc acaaaatcat ctgcccccat
    31141 gttcatagcc atgatcatat ccatattcgt attcctgctg gagataaaaa tgatcggtac
    31201 tttcgatact tcacgtattt tttgacacca ataatagcca tccaaaacgg gaagattaat
    31261 atctagtaat acaagctgtg gttcttctct ttcaaagtct gagaacactt gattgaaatc
    31321 ggtcgttcca aaggtttcaa attgccattt ctcaagttcc tccatgatca attgtcgaat
    31381 gatctcttcg tcttcgacta ccatgatttt tgccataaaa aatccctcca tctttcttct
    31441 tgctactaca atatcaaaga agcccttgtg aaacaagttg gcttacctgg aaaatgtcat
    31501 tttagcaaac gttaaaaaaa actggaaata tgcgatttaa tcgcgtttgt ctcttccaag
    31561 cagcttaaat ttattatgtt attcttaata attggtctat tatctgttat ttttctttcg
    31621 ttgtttttgt cttttaaatt ttcgataaca ccaataaccg aaaagcgtta gcactagcaa
    31681 tatacctaga aggagtataa gtaatcgata aagatggtat ttttttgtct gttctatctt
    31741 tgaagagact tcttctgtaa agggaactcg tcttcctgtc actagtaatc ggtgagtgtt
    31801 cacggtgtaa ggtgtacaag tgataagtgt gactagatcc tgcttttctc taattgctaa
    31861 tgtatttgtt tttgttggaa ggacaacaat tttctcaacg acttcataag cgagcatccg
    31921 accatacact tcaagataga atcggtcatc ttgctccatt tcttcaagat ccgtaaagag
    31981 ttttttctca gcaataccgc tatgggcggt aatcacggaa tgtgtactct ctcctccagt
    32041 tggaaaagag gtgccttgca ggactgtcgc tcctctatct aacaaaagat cattcgtttc
    32101 atcaaataaa ggcaagctaa cattgatttt cggaatatag atggctccga tcatatgttg
    32161 ttcgtaatat tcttttcctg gattttggac atttctaacc gcttgctcaa aaggatcttt
    32221 gacttgtccc attcctggga ttactgatgt atgagcaagc gtctgatttt tcttttcatg
    32281 cactgctaat tgttgctcat gtttttcttc tttatcgcgt tcaagctgct tttgataatt
    32341 ctcgatcctt ctttgatcca aataattgct gagagcatct gctaaaaatg gatatgtaaa
    32401 aactgcagct ccggcaagaa acatcactgc cataaataat tgtaataaaa gactgatttg
    32461 ggtttgaggt ctattaccta ttttcttttt cattttcttc accttcttat ttaaaaaaac
    32521 tgcagcaacc tttataaaac cgattgctgc agcttatttt tgttgcttat acttcagact
    32581 tcattttaga tttacggtac cagctgtacg ctccaatcat caaacttatt ccgattagta
    32641 agaatgccaa gagcccgttc ccaccagtag caggaagtga cccgcgtttc atattcggta
    32701 ctctttctgg ccctggattt tctactccta cgatctgaat ttcttcatta tagcttccat
    32761 aagagatgat aaattcagta aaggctgcct cacctgttgg aagtacataa ccttctggcg
    32821 ccatggtctc tttcatttga taggttccat aatctaaccc ttgaacctca aagtatccat
    32881 ttccatctgc gacaaattct gttgcttgtc cgcttgttgc ccactcaatt ctatctgctc
    32941 ctgattcata aacagctaaa ggcgactccc ctttataaaa tattgcgtat tcagaacggt
    33001 cttcattcca caattcgaat cttgcatctt taagcaattc actgcttgat gcatcatatt
    33061 tttcaaactt tcttccacct gttgtgactt tctctggcgg ctctactcct tcttcataat
    33121 caaattcatc atttcgtccg atttcaataa ccgctgtgtt gttatggaaa tcatccgctt
    33181 ctagttctgt ggaaaccttc aaattatacg tgatcgttaa atctcctcca cgtgcatctg
    33241 ctaatctacc taaagtatct actttggcta ctccattttc ttctgtcaaa atcgtcacga
    33301 caaacccgtt gcttactact tctactatat aatcttgtcc ttttgttaaa atcgtctcgc
    33361 cggctcgcac ttctatttcc tgatcataat aagttagacc aactgtaggc gtatctgtga
    33421 ttttgtaatt tttgataaca gcgcttccgt tttcaaggac agaatcgatg aaataaggaa
    33481 taggtgctgt gatcgtgtaa gaagccgttt ttcctctttc tagatcaata taagaaatcg
    33541 tttcttgttc tccagcttca ttaataatcg ttacttgtct aaggtcgctt tcctctacat
    33601 tcatctgttt atctgcttct ctgatttcgt ttttcggata caaatgcaca tctgtattgt
    33661 atgtgtcttt ccatgtagaa ccatcccaca cgccatccac catatcaggc atcatcactg
    33721 gcatcataac aaccattgga gacgcgattc tggaaatatg agctggcgaa taagtttcta
    33781 agaaaagata gactttatct ctagaagaag gtgcttcttc cgtcacttgg acggtagaga
    33841 ataccgcttc tccagcttca ttcgttgttt gtttgtcaat acttgtcagt cgatatttta
    33901 aaaaccaact ttctgtgtgc cgtttttgaa tccattcaat cgcttcggca gaattaagac
    33961 cgtcttctcg ttccggtgtt aaaggattat ctcgaatcaa atcgtaatat acttccgtta
    34021 cgtcaaacaa atcaaaatcg actcctggaa tattttcttc accaaaatcc gtagaaacca
    34081 atccgctatt cggtcgttct tccggaacag atgagaaacc ttttttgtgt aatgtaatcg
    34141 tcacttcact tggtttttgt gcgacttctt cggctttgac tagttttccg ttcccgaaaa
    34201 tccctattcc cgcagtaacg agtaacagta cactcattcc cgtgacaatc atttttttat
    34261 tcattttttt ctccccgttc tttttttatt aataaaacag cacctaacaa taaaagaatt
    34321 cctagtaaag aaatcaacgt tcttgcttca ttcgtttgcg ggaatacgga ccattttcct
    34381 gattgacctg gattgcttgg accactcggc tctttcggtt tgtccgttgt ttcttttacg
    34441 gtctcgttat aaacacgtgg tgttgcggat tcataggcag agactggaac tttcccggat
    34501 tctaattcag ccatctcctg tccgttaact actacatatt gtggttggcc ttttgcatcc
    34561 acccaaaatt cagggatgat gacctcgatt ctcttacttg cttcatccat ctcgtaacct
    34621 tccacacctt ttaattcttc aaaataatag gtgccagaag gcaagaaacg ttgtcctgtc
    34681 gtaacaaggc cctctttatc cgaaatgaat ttgcttacat ttttgtcatt caaaggatca
    34741 ttgtctgctg gtttgatcca ttgatttttc aagtcattag caggagccat atctaaataa
    34801 tatttccccc cttctatcat ctgatataga gcaaaaacag caccttctaa tggttttcct
    34861 ttttcagttg ttcctctttg acgtccatac ttgaagaagt atggatctct tagataaccg
    34921 acatttttag gatagatatg aatctcttgc agttcctcgg ttgattctgt cgggtgataa
    34981 attggcaaaa tagcagcaat tgggatagct gtctgatcga tatcaacatc caatccaact
    35041 tctggatcaa tcgattcttc gaaaatcaaa taaactgcat cccgatcttg gtttttctta
    35101 ggtgctttga tacgtgcaat cccgtctcct aatccgccaa ccgtatcttt cccagttgtt
    35161 accgaagtcc ctatttggac aagcctttct tctgtgatta gctgacggat attgtttctg
    35221 ttcgtttcag cgatttgctg gacgaattct ttaggagtca tgttttcagc agcttttttt
    35281 tcatgataat aatcggtcat gtcgtaaatg gcaaatgtcg ctccatttag tggcaccgtc
    35341 tgtgaaatga tatctgctgt ttcccctgct tcctcagaga tagccaagcc atcattttca
    35401 tggtattcaa attgatcgtt ataatcgata tctcgaatca tccgtttatg caacacgaat
    35461 tccacgacat cttcccctga ttcttctgcc gacatcgcat gtggaagaag gactgctgca
    35521 agcggtagta aaacaagtaa ttgaagcatc aaacacaaca gctttttcat taccttgctc
    35581 cctccttttt agattgtctg acaaacaaac cataggctgc tcctgcaagc gccatgaaga
    35641 atgcagcaag caggatatag aataatcgtc cggatcctcc tgtagcaggc aacggatttt
    35701 caggatcgtt cccgacacta agctgtaatc tgattcgatt tgtctccaaa agttcatatt
    35761 ctaactcttg ctgtagatca ggcgtctctg cttcttcgtt tggataatac gaaatctcaa
    35821 cttttagtgt acccgcttct tttcctggaa ctacccgatc attttctatg tcaggttctt
    35881 ctcgataact aatttctaaa ataaagtaac ctggaagttt tctatagctg tcaggtgact
    35941 tcacttcctt gatccgatag accccttcca acaagtctga agcattgaat agggaagaat
    36001 cgtttggatc tggtgccaag cctccctcga tgatttcata ctctcctgca ctattttgtt
    36061 tctcaattga aaattctgcg ccttcaagac gtcggctatt catactgtca attttcaaaa
    36121 gttccaaatc gattggcgct agttcatctt ctaaggttac ttgtagtaca ccatcgatga
    36181 tttcatagcc ttccggcaag ggagcagttt cgtcttcgat gaccgtatct tcaatgataa
    36241 acttaccttc ttcattcagt gcaaactgga acacttgatc agatagccga tacccatttg
    36301 gtgcgacaga ttccgagacc tcatattcac caatagacag atgcagaggt tggtcgtaat
    36361 ttaaatcgac atacttttct actcctacgg cacgagaata gaagtatccg atcccaggca
    36421 aacgtttcga ttcttctggt tctaacggat taccagtgta tgctcgatac agcgggaagg
    36481 aagaatcccc cactttcctg atatcgaaac ctgcaccatc taatgtatgg ccttcatggt
    36541 ctaattttct aactcggatc tcccgataat caaacgtatt gtaagcagtg aatgctaccc
    36601 ataaacgatc ctcttcatct gttgtatacg tgagatattg ccaattttct tcacctgttt
    36661 gcttgagttg gatagtccct atagcattat cgtaaagtcg caagatccat gtgtcatttt
    36721 catcaggttc tttgaaacct tctgggttct ggctctcaat gattttgtat tctgcatagt
    36781 tggtagtttc ttcactatcc ttataaacaa atgaatctgg ctctccgatt ggatgaataa
    36841 ctttctcacc atccacgatt acatatttcc cgtcttcatc tactgaatag aacgtgagtc
    36901 tccctttctc ttcctctact tcgttcacac cagaaagccc tttcgctact ggatatccga
    36961 tttccagtcc gttaccatct gtttcataaa gttcaaactc tgcgccattg attggcatat
    37021 tactgccttc aattagttta ttgatattca tgtggattgg cttgaattca tttcgcattt
    37081 ccagtttgac atacaactca tcatactctg tgccttctat gttaggctct tgtacaacag
    37141 aaagcttgtg atattctcct tcataatagg aattcggatc tttaccttcc ggtccgccga
    37201 ctctcgaacc agatgtatat tcatctacaa gctcgtagtg acctaacatc tcatcttcgt
    37261 tggctgcata ttttttgatt tggaattgat acgtctcatc tactaactga taacgtggtg
    37321 gtccagcgat ctctctgatc caaaatatgt cgctgactgc tccagtttca tctcctaaaa
    37381 tcggcatctt cgtttcaaag atcgctattc cgtccgtggt agttttactt gtttcgattg
    37441 gttcggcttc cccactctct ggattttggt catataatgc aaattcgact ccagccaacg
    37501 gctcgccatt ttgacccttc ttgctgactt ggaaattacg gcctttatgt tcgtaacgaa
    37561 tggaagaaga tgggaaatac atccgtccag tagtgatatc attctcataa tcctccaggt
    37621 tctgaatata ggccatattg ttcactgtgc aaaaatttcc gtcttgagct cccgcatcaa
    37681 gttttacttg gtacttgatc ctgaccattt ccccttcacc taaagaaatc ggagaaaatt
    37741 tataagcttg gttttcccgt ccgacatacg ttgtcggagt cgccactact tctggtgggg
    37801 cttgtccatg acgttcttca tcccatattt ctggctcttg gtacttcatg ccgttttctc
    37861 ctggatctag atggtaaaac tgaatatctg ccgatctgcc agctccaaat ggtgagacat
    37921 taaaaccagt ttcatcataa agtgtggctt gctggatcgt tctcttgaag gtagaagaga
    37981 tatcctccaa ggctgtaaca atgtcattct tgttgttcgc attgtaatat cgcggtgtta
    38041 cgccatcttc ttctaaatca gcaatatttt tcaatacatt tcgtccaata gcatctagtc
    38101 gttgtctccc gctaacgttt ccatcgattc ctaaaccaat ggagaagata cttggcgggt
    38161 tctcttgata cttgtttttc agccaatgat gataagcaac tgtgttgatc gcagatgact
    38221 tttcttgcga agtaggactg ccattcgtat tgttattaga agaaccatca ccaacccagt
    38281 gagtcgcttt attatctcct tcttttacct ctccataacg atagtgtaca tttacttcat
    38341 cttctggacg gttaaagtca gatgcatagg taactggatg agtaaaccct gcattagaag
    38401 tattcccaga aaactcctca aaatttctga acaaaacgtc attatcttca gcaatcttat
    38461 cttccatcac agtccagttg ctccaagctc cattagtgct cgtacgataa cttgactgaa
    38521 tcggtgcata actgaaggtc ggtgtcccat ctcccacaac gattaggatt ttttctggat
    38581 ttctattttc tccgccattg tctttataca atgtttcata gccattttta agccctagtg
    38641 taagcggagt tcctccgatt ggtgtacgat ttaatgctgt attctcactt cccgtcaaac
    38701 gattgatatc atttgtcaat ggaaagatgt ccgaactgat ttgctcatgg ttattgatag
    38761 ctgtactatt atggtaaaaa ttcaccatac cgattcgaat atccagactc gggtcagaga
    38821 gcagatcttt actcatttcg tttactgcct caatcaacgc agcattttta gtttgactat
    38881 tggtcccagc ggttaattca ctcatactcg ctgacttatc tagaacaaaa acgatatcga
    38941 ttggactgat ttcctttttc tcgcccccga tgacatctag atagacattg taaagggttg
    39001 ttgcatcttc aggatgtaga tcagatgctg tgctgcttgg cagaacaggt tctacccatt
    39061 ttttgatgta cgccccgtta taatccaagt aactgttttc aaaattccgt tcatttcccc
    39121 aaagctgaac ggtttgagct ggaacgtttc tatcttcttc gcctgcagtt gatccattat
    39181 tagtagcata gtcgtaattt cgccagttcg ctcccccgtt tgtataatca ctatcatcga
    39241 tcaagttctc tccgtcatat ggcgagcctt tgtctccttg atagcgttca ttgctttgtg
    39301 tccaatttcc taacactttt gtatagtcat tcgttgtaaa cttcgggtag cgatgctgtt
    39361 cgttttcaac ttctccgcta ggatagatat attcataggg gtcttgcgta gctgttggcc
    39421 caagacgctc caaaataccg ttgaataact ggcgttgaat gcgctggagt gcttgaccgc
    39481 tgggtacgat tggttcgtcc agcttttcca tctcattttc ttcgctacgt tgaatttcag
    39541 cggaatcttc tgtatcagtt tcattttctt gtaattcttg gttatctatt ctttcatcaa
    39601 ccaccacttg aagaggtagt tacccttcgt tcacatcggg gatcttttct gtttcaaaaa
    39661 tcaatgtgcc ggtttctgct tcttttgaat aaacttttcc gacataccat tcttgaccat
    39721 cgatcgtctc gacttttagg tcttctccat cttcatcata ggaggataga cctgttccac
    39781 gaacgttttt tacggtacca atcccggcgg ctgccgcatc gattgctaaa cgtattctac
    39841 cttcattggc actttccttt ttttcaaaag ccagatgcca ttcaagggtt tcttcttttt
    39901 caatatactt cccttcaatt tttgcatagt cctcatctaa gaatacctca tcctcctttg
    39961 tttctgttga ctcagcagct acatccaggg tcgtcatatg atagactgac tggaaatatg
    40021 gtccaaatag caaactgaca gttactaact gcaaaagctt caattttaac cctttcacat
    40081 ccttatactc ctttcaaaaa tatttgtctt ctttcacaac aatcaacaaa acaatgccca
    40141 tctaattata atttaattta attttaattt taaatcaaat gatatccttt ttagttaaaa
    40201 aacaccaatt atacaacatt tattattaaa attaaattat aaaattttat aacgttctca
    40261 tttaacaaaa cttaagttat taagacaaat gaataaacaa ctacgctttc ctcgaaacaa
    40321 aaaaataaag cacaaatgcg catttacgca ctcatgcttt attcgtacaa ttaattcaga
    40381 taacggcagc gcataggatg ccaataacac ttcctaaaat agctcctcct aaaatgtcag
    40441 taggataatg taaaagtaaa aaaatcctcg aataagcgat caaacaagca aataaaaagg
    40501 ctaatattcc tgcaactgga cttaattcga acaacgcagc tactgataaa aaggctagcg
    40561 ctgtatgtcc tgaaggaaaa gaagaagtct tcggtttact tgtgtaaagg acaagccgac
    40621 gatttttttc ataaggtctt ttccgtcttg tcgttttttt gataaaaagc aaaccaacaa
    40681 aaaaatagat caaactgccg ataagaatgg ctagaccata ttctctagta tcaggtatca
    40741 agactaaaac agcagcaagg agcaaccaaa taaaaccacc attagagata ttactgataa
    40801 atttcaaaaa attgattttt cgactatccg ttttccgttg cttggcgaac ttgttgataa
    40861 tactatcatc gattttagca atcaaacgca acatgttatt cctccttttt aagaaccttt
    40921 tcttgcgtac gatggataaa aagcaggact tgaaaataaa acaagaaact gaaacctaat
    40981 aaagcaaaat agattggtcc tgcaaaccag aatgcgacaa gaaggatcaa cgtgcctgcc
    41041 aaatagaaaa gcgcgctttt gaaatcatta aaaaacaaga aaaatgcagt aatccaagaa
    41101 gcttcttttt gttccagttg aagcaagatt ttgtaactaa agagaagcgc gcttaataga
    41161 agcaaaaaca acgtagtata catcaatgta tagccaattc ccccacccca atagcggaaa
    41221 atctgataat cgatcaatag aagaagaaaa taaacacttg ctaaactatc ttgctttcca
    41281 taaagagaga agttctcacg aaactttttc cagaatagtg aaccgagctt tttctcttca
    41341 ttttttttgt aatgataaat catatacaga actgttcgac ttgcagttcc taatgtgaaa
    41401 acaggcaaga cgcacaggaa ccatagtagc tgtaaatgga taagacgtgg aatccattca
    41461 atgatttcta agaaataatc attggctttt ttaccaatcg atcgattcat catccttttg
    41521 aacctcctgt caaatccatc ccttcaatga aataacgttg tgcaaaaaag aacagcaaaa
    41581 tcgtcgggat caagacaagt gttgctcctg ccatcagata attccattgt gtcgttgctt
    41641 ggttctgaaa aacttgcaag ccaatctgta acgtgtattt ttcttgatct tggatatata
    41701 acagaggacc taagaaatca ttccaagctg cgttgaagga attgatcgca atggtaatca
    41761 aggcaggttt cgtcaatgga agcatcaaat gactccaaat atacaaatga ttcgctccgt
    41821 cgatttcagc agcttcgatc aattcattat tgatcgataa gtaaaattga cgcatcagaa
    41881 atatattgaa cgcattgccg aagaacgatg gaacgatcag gggcaaataa gtacctaccc
    41941 agccgatctt ggagaataat acatattgag ggatcatcgt tacaaacccc gggatcatca
    42001 tcgtagaaag aaccaaagca aacatcagct ttttcccagg aaaatcaagc ttcgcaaatc
    42061 cataagcaat aaaagaattt gaaaggacat taccgatcac tactagcaca gtgatgaata
    42121 atgtatttct tgcatagcgc caaaaaggaa aggcggcaat cgtatccaga tagttttccc
    42181 atacgatttt ttctgggaaa aaggtcggag gataacgaac gatttcttcc attggtttca
    42241 atgaagtaaa caccatccaa agcaatggaa tgatcaaaat gattcctatt actgtcatga
    42301 ggacataact tagtattttt tttgtttgcc gattcacact ggtctttttg aaataatcca
    42361 tcatttgccg tcacctccag aataatagac ccacttaggt gcaagcttca aattgacaaa
    42421 cgtcagaacc aacacgatca gaaacaggat cattgacata gccatcgcat aacccatatc
    42481 aaaagctacg aacgccttgt tccacatatg cagattataa aaaagcaaag aatttgcagg
    42541 tccgcctgtt ccatttttcg tcatgacata agcttcttga aaaatttgga aagaaccgat
    42601 cgtagaggtg atcacatcgt aaaaaataat aggagtgatt aatggcaaag taatactttt
    42661 gaactttccc caaacgcctg ctccatcgat ttctgctgat tcatataaag atctaggaac
    42721 attttgtaat gtagctaagt aaagtagcat tgctcctcca gaactccata ttttcatcaa
    42781 aatcaacgca ggtttcgtcc attgtggatc aaacagccaa gctggtccag ggatatggaa
    42841 ccagcccaga aatgtgttga tcaatcctgc agatggagaa agcagctgca tccataagat
    42901 gtagactgct actcctgata agactgccgg taaatagaaa gctgtacgga atacactgat
    42961 tcctttgatt ttttgattga gtactgtggc taaaaacaca ctgaaaatcg tcgtcagcgg
    43021 tacattgaag atgacgaaat aaacggtgtt gtataacgat ttccaaaata aatcatcgtg
    43081 aacgaacatt cttttgaaat ttgctagacc aatgaaattc atcttggatg tcaaattata
    43141 atcggtgaaa ctaccaataa ctgaaaaaag cataggccct agcataaata ccaagaaccc
    43201 gataataaaa ggcgagataa ataaataggc ccatcttgct tcttttttct ttcggataga
    43261 taaacgcttc aaattttctt gcctcctctg tacctagaca gtcaaaaatg gattattgat
    43321 tttgcttgac taagttttct actgcttttt gtgcatctgc caatccttct tttggtgatt
    43381 ttgttcctaa aagaatctgg tcaatctgtt cattcactaa tgtcgtgtaa tccggagcat
    43441 ctaaaggaac tggtgtgatc accgtatttt taaagttttc gtccgccatt tgatagatca
    43501 tttttccttt atccgttagg ttgtcattat tcactaaatt ctcattggct gtcttgctcg
    43561 ccatgatatc aaaacttttt tcgccgaatt tttcttgtac ttctggagaa gaaagatatt
    43621 tgatgaattc ataagaggcc tcaggatctt ttgctccgta tggtacttcc aagacgaatc
    43681 cgccacccca cgaccaatgg cctgaacctt cttctttttc tgggagctgc atcacgccaa
    43741 aatcaaaatc atccggtgca ttttccatca aactagagta ataattgata ttttgggcac
    43801 gcatggctac taatccggaa ataaatggat cagatacacc agacccaaat tcggcttcta
    43861 atttattgat cgtatttttc ccataataat cttgccagtc ttggatccac tccaaggctt
    43921 ccactttatt tttagtatca atcttgactt tttcatcttt gtcaaaccaa ctagtcccgt
    43981 tatctgcgtt tagcgcccat acatcagccc ctaaattcca taatggataa aaaccgatgc
    44041 gtgtaaattc ttttccttct tttttatcta gtttacgtgc tgtttcttct aattcatccc
    44101 aagttgtcgg tagatcttgt tcactgattc cagcttcttt aaataacttt ttattataaa
    44161 aaatgacttg tgtatctgta ttgaatggga tcgcataagg atcaccttca tattctactg
    44221 tatcccaaag ctgcggataa aaatccttag aagtgtcttt ttctacatat ttggagagat
    44281 tagttgcttg ctgtgcttct gctctttggg caacggaatt tatgtcctgt acaataacat
    44341 cgggtgcatt tccagctgtt attgcagata aagatttagt ccagatgtca ccccatggct
    44401 gatacttata atttacatgg atctcgtttt gtgattgatt gaaatcctca atgatttctt
    44461 cgatagcttc ttttcgtgca ccggatcccc aaaaggacca gaaatcaata ttttttcttc
    44521 catcacttgt tttttcagaa gaatttgctg cacttgaact ggcatcgctt gcattacttg
    44581 atccgcatcc tcctaataaa aacaatgctg aacttgccag caaccctgta aacaataatt
    44641 ttttcatatt ttacctccaa attttaatgt aaccgatgcc ggttttaata taacgatatc
    44701 attttgttct gaaaataaca atttataagg tatgattcta aaaaaattat taatgatacc
    44761 aatactttat ataattcgcg agcgctttct ttgaattttt taatctttcg tagcagaatg
    44821 agaatgtatt aaaaatagat taggaggaat tttgatgttt agacaccaga aagaattgca
    44881 gtttgaagca aaaccagatc gtccgaatcc attaatcgcg aaatatctgc aggagctgat
    44941 cggcggccaa tatggcgaga tgagtgtagc tatgcagtac ctgttccaag gctggagctg
    45001 ccgaggagaa gaaaaatata aagatatgct gatggacatt gcaacagaag aaatcggcca
    45061 cgtggaaatg ttggcgacaa tggttgctcg tttattagag ggtgcgcctg ttgaagatca
    45121 agaagcagcg atgcaaaaag atccaacaat cggtgccatt atctctggaa tgaatccaca
    45181 gcacgcgatc gtagctggct taggacctcg tcctgctgac agcgtgggca atccatggag
    45241 cggtgcctat atcattgcga gtggcaactt gttagcagac tttagagcta atttaaatgc
    45301 cgaatcacaa ggaagacttc aagtagcacg tatttacgaa atgatcgatg atcgtggcgt
    45361 aaaagatatg ctgtctgttc tccttgcaag agatagctat catcaaaatc tatgggaatg
    45421 tgcagtgaaa gaattagaag aaaaagaagg ttcaatctta gtcccaagta ctttcccgcg
    45481 tgacaaagaa cgaaaagaca ttgcttatga cttctataac ttctcagagg gagaccaaag
    45541 tagtgaaggt tcttgggcta gtggcaaagc actggatggc gaaggcgaat atcaatggtt
    45601 gaaagaacct aagatcgaag gcgctgcacc aaaattagaa ccagtaacac caaaaatgta
    45661 tgggacacct ccattcaaga aataaatatc tacccgtaga aacacccgtt ttttgttcca
    45721 cacgctttgt gagcaaaact gactaaagtc attaatcata accacccttc aaaagggtgg
    45781 ttttctctag agctataagc tcaaatcacc ggccagcgcc taaagacgct ggctttcata
    45841 ttttatgttc aagccatatt gcctttgcca gttttgccca cctcttaaaa ggtttatgta
    45901 ctactcctta gcccttaaaa ggatcgtctt actctcgtac actcagctta tctaacgcac
    45961 tatcatgttt ttcttgttct tgaatgtact ttttgatggt cgcttcattt tgtcctactt
    46021 ttgtcacata gtatccttcc acccaaaagt gtcgataccc aaatttatat tttagatttg
    46081 cacaatctct tgatgatctc ctgaatattg gctcgatatt gattataaat tatttttctt
    46141 ctatactttg gtgtgaatac aatgtggtat ttacacatct actttgtacg ggctaaacta
    46201 tttcccttta ttgctccacc cgcatagcaa gtggttttgt atttcaatcg ctcggcgcgc
    46261 tcaattaggt ctaaagacaa taaatctaaa aacccgctgc ttcactgaca gaaacaacgg
    46321 gttttcagaa aaaaatgaaa tgaaaaagat ctcttacggc aatctatttt atttttttga
    46381 ttttttataa atggaaaatg cttcaagaag tccaagaaat aaagccgtat aaaaacaaga
    46441 acctatgaaa tctttattta ttagatattc aacagaaatc ccgataacac tagccaacaa
    46501 tatatttatc agaagtgtaa aataaggatg ctttttatag aatagaacta gtgttgtttt
    46561 catagactct cctttcttca tatttccaat taatcacaaa ttcacggcat tactagaaaa
    46621 attaaagggg cgcagaagtg gaaaaatact cttcgacttt ccctacaaac caggccatct
    46681 tgtgtttaat aactatacca aatctaaggt acctctaaat ctaaattcca tttgtggcgg
    46741 tgacctccaa tttttaactc ttctatctcc catccagtat acataacctt gatacttcga
    46801 ccacttatat atcgaacaca caaataccta tccattgcag gagtactacc taacttagtt
    46861 gctacttgca tctaaataac agctgaaaag ataggactta ctcttagtaa agtatctgaa
    46921 ctattaattt ttaaactatc atttttatcc tcaactacat gcacatctgt tgcaacttca
    46981 ctttctgtct catccagata aatgattaag gaatcgggaa ttgcaatatc ttcagctgac
    47041 gctggaatag ttgagctaaa ttagtcatca tatctttatt ataaaataac caacagcaaa
    47101 aaatacaatg aaaaacaaac ttggaactaa tgtatcatta ataaatgttg aaaaattcag
    47161 caactcatta ctgtatgatt ttagcagccc aaccaacata taccctataa aagctaataa
    47221 gatggttagg aatcctttag aatttttact cattcataga cacttcctta aataactttt
    47281 attatagaag gtattgtaaa taataatatt gacaaaaagt gactcaaaat aaaaaaaacc
    47341 ttacattata ctggaatgaa ctgtattgat agtgtaccta aaagctctac tgacataaga
    47401 tcgtgtaatc ggtaaagtaa ttttattaat tatacgggat gtaatcaatt agagaataaa
    47461 ctaatcataa aaggtacttt tacattcata attgtcgctt tgagattcta ctttggttca
    47521 ctatctgacc caattgcaca ttttcgatca ttacaagtat tggtgtcgtt agaacaacta
    47581 aataaaaact agcggtagat ttttcagaat ctatgctaat ttctgtatgg atgttccagt
    47641 gatggcaaat ttctcttttc attgtttttc ttgtcgcatg atatgccttt ttgtgttatt
    47701 cagttaaact atagaaattc tttcctagac agatcttgat cccaaatttt acgtttttga
    47761 gcatcgatat agtttaaaat gacattactc atatctaaag agtttagatt ttttaggact
    47821 aaaactgtca gttgttcttt ttcttctttc tgttaaagta ttgtcgcgac ttttcgtata
    47881 cgttaagata tgtcgtgaaa aaacaagttt tgtgacacaa aaaaacgaat gacttgagga
    47941 aatcacctca atcattcgtt taaaatgcta tatattcttt agtttaagat acggaaatta
    48001 atgccatcga ccacactagt agaatgaacg acatttactt ggcctttttt taatttcgtt
    48061 atgtttagca tataaaaata ttatagagtt tacttacaat gcttaaaaca tatactgtat
    48121 aatctgatca attttagcca tgtcttgcaa tggtaagttt tctatttttt tgagttttcg
    48181 ttccttaaaa tcaagagatt ttaattgtgt aataattact tgtcctttta tatctagctc
    48241 ttcaggtaat gagtaacgtg tcggtaaatt ctttatagtg gaagtaattg gacatatgac
    48301 cgaaaacatt gttttacggt taaattcata acgagagacg actagtcctg gtcgtctttt
    48361 ttgaatttct tttcctacgg agggatcaaa atcaatccat acaatatcac cttttttagg
    48421 aatataaatt ctttcttctg acactataaa atttctctcc cttcaggagt taaatcttcc
    48481 cattcgtctt tctcataata ctcggcctct tccccaccac taaatggatc ttcaattttt
    48541 ggaactaacg taattgttcc atcatcagaa tacacaacga tatattcttg gttttctgaa
    48601 ggtttctttc cgttatcaga aggtaaagtt accactacag aacttccttg taatctagat
    48661 tttgtaacaa gcattatcat cactccctta ataaaagtat actatataac actaagtaac
    48721 gcaaaattcc cctttgtaaa ctatctagaa aattgttttg tttaaagtat atcttattgg
    48781 atataaatag aaataaattg tagccagttc attttttctt taactaaaaa aataatccaa
    48841 gaaacattga acctatggat ccaaaagcta cccaaatact atagctaacc ccccgctacc
    48901 ttcaattttg cagataaaac gctttgggag aaaatttcaa agacaacagg ccatcctatc
    48961 atgcccgatt ataaacaaaa agctggctat tccttttgct ctgacaaatt tcaattggga
    49021 aagttcacga aactagcagg tgaagaagtt tcaactgttc ggatcaaaga atgcccgctt
    49081 caaatagaaa cattggttca acgaatttca actagacaag actttgctat tgtagaacgt
    49141 gagatcgtag ctatttttgt agaagaaggg attttacatg atccaactca tatcaatgtg
    49201 gataaatggc aacctcttat ctataaattc agagaatata caactgccaa ccagtcgtta
    49261 actttgaatt ttagattcca agaattcaaa gagtcataat gataaacatc gttaggtata
    49321 aataaaaaag actcgcagca cgagtaaaaa acaaatagaa gctatacatt agaaaggtcg
    49381 actgtgaccc tatagatgca gtatatgcag cttatgagca tttcttctgt tctctttgtt
    49441 tttgggatct gtgctgaagt ctttttcgtt ttttgccgct ctttctttga aaaatcgatt
    49501 atgttatacc ttctccatta ctaattcagg catctgctga gtaatgattt ttcgcgcaaa
    49561 agaaatatct gttacccaag gttcgatttg ttcttcagtc aagacaagcg gcattcggtc
    49621 atggattggt gcgactgtgc ggttaggttc agtagtcatt atgattgatt ctgccatttt
    49681 ttcatcctga tggctacgat aaaaaccgcc aatatacact attttttcct tatttgaaaa
    49741 cataaatttg tctttttctt cattccactc attgggaaaa cacaacgatt ttgcaaaaat
    49801 ggttgatgaa aggtcttttt ttcttctact gtctctgcac gggcattaat catcaattgt
    49861 ccttttttaa atccggtaaa tccccacttc atgatttccg gagtgaggat gttttcttcc
    49921 tcttttctta acgtcacaac aagatttgac ggaaaaactt ctccagctgc taattctgct
    49981 gcctgcttcg gttgtttcgt ctgggcttct cgataataat tctgaaggag ctctgactct
    50041 agatcaaaaa aataacgacc acacatccta atccctccca atcttttttt ctatcataca
    50101 ctgcaacaag aagttcgcac caacaaaacg ctttcaattt ttgtagaact aaaaaagttg
    50161 tgacaagtga caaactctcc agtgaatggt attctcctgc caactcctcg gtcacaagtc
    50221 acaatattca acaaacatga gaagctgctt tttgaaattg ttccttgtga ctcggagtga
    50281 aacggcaggc ttacgacctc tgggtaaacg gtgttcaaaa gccagtttct cggtattaag
    50341 ccaaatttat gcaaaaatgt agaaagctat tttcacaaaa tttttctta
//
LOCUS       DBBGSP010000016        49999 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000016 DBBGSP010000000
VERSION     DBBGSP010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 49999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.016"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(2..1012)
                     /locus_tag="ACIZE9_001086"
     CDS             complement(2..1012)
                     /locus_tag="ACIZE9_001086"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC6092962.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1192..1536)
                     /locus_tag="ACIZE9_001087"
     CDS             complement(1192..1536)
                     /locus_tag="ACIZE9_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGC6092963.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1529..1963)
                     /locus_tag="ACIZE9_001088"
     CDS             complement(1529..1963)
                     /locus_tag="ACIZE9_001088"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGC6092964.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2101..2838
                     /locus_tag="ACIZE9_001089"
     CDS             2101..2838
                     /locus_tag="ACIZE9_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6092965.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2831..4042
                     /locus_tag="ACIZE9_001090"
     CDS             2831..4042
                     /locus_tag="ACIZE9_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6092966.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4246..5028
                     /locus_tag="ACIZE9_001091"
     CDS             4246..5028
                     /locus_tag="ACIZE9_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HGC6092967.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5098..5760
                     /gene="trmB"
                     /locus_tag="ACIZE9_001092"
     CDS             5098..5760
                     /gene="trmB"
                     /locus_tag="ACIZE9_001092"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGC6092968.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5858..7612)
                     /gene="ade"
                     /locus_tag="ACIZE9_001093"
     CDS             complement(5858..7612)
                     /gene="ade"
                     /locus_tag="ACIZE9_001093"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HGC6092969.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7744..8673
                     /gene="comGA"
                     /locus_tag="ACIZE9_001094"
     CDS             7744..8673
                     /gene="comGA"
                     /locus_tag="ACIZE9_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGC6092970.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8630..9679
                     /gene="comGB"
                     /locus_tag="ACIZE9_001095"
     CDS             8630..9679
                     /gene="comGB"
                     /locus_tag="ACIZE9_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGC6092971.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9676..9954
                     /gene="comGC"
                     /locus_tag="ACIZE9_001096"
     CDS             9676..9954
                     /gene="comGC"
                     /locus_tag="ACIZE9_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HGC6092972.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9929..10399
                     /gene="comGD"
                     /locus_tag="ACIZE9_001097"
     CDS             9929..10399
                     /gene="comGD"
                     /locus_tag="ACIZE9_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGC6092973.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10371..10718
                     /locus_tag="ACIZE9_001098"
     CDS             10371..10718
                     /locus_tag="ACIZE9_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092974.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            10681..11106
                     /gene="comGF"
                     /locus_tag="ACIZE9_001099"
     CDS             10681..11106
                     /gene="comGF"
                     /locus_tag="ACIZE9_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGC6092975.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            11078..11437
                     /gene="comGG"
                     /locus_tag="ACIZE9_001100"
     CDS             11078..11437
                     /gene="comGG"
                     /locus_tag="ACIZE9_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGC6092976.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11609..12616
                     /locus_tag="ACIZE9_001101"
     CDS             11609..12616
                     /locus_tag="ACIZE9_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6092977.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12641..13825
                     /locus_tag="ACIZE9_001102"
     CDS             12641..13825
                     /locus_tag="ACIZE9_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HGC6092978.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14262..15845)
                     /gene="abc-f"
                     /locus_tag="ACIZE9_001103"
     CDS             complement(14262..15845)
                     /gene="abc-f"
                     /locus_tag="ACIZE9_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HGC6092979.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIVLVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(15950..16078)
                     /locus_tag="ACIZE9_001104"
     CDS             complement(15950..16078)
                     /locus_tag="ACIZE9_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092980.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(16423..16566)
                     /locus_tag="ACIZE9_001105"
     CDS             complement(16423..16566)
                     /locus_tag="ACIZE9_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HGC6092981.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16789..17268)
                     /locus_tag="ACIZE9_001106"
     CDS             complement(16789..17268)
                     /locus_tag="ACIZE9_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGC6092982.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17341..17625)
                     /locus_tag="ACIZE9_001107"
     CDS             complement(17341..17625)
                     /locus_tag="ACIZE9_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6092983.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17703..17897)
                     /gene="ssrS"
                     /locus_tag="ACIZE9_001108"
     ncRNA           complement(17703..17897)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACIZE9_001108"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17969..19255)
                     /locus_tag="ACIZE9_001109"
     CDS             complement(17969..19255)
                     /locus_tag="ACIZE9_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGC6092984.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19393..20064
                     /locus_tag="ACIZE9_001110"
     CDS             19393..20064
                     /locus_tag="ACIZE9_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HGC6092985.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20030..20518
                     /locus_tag="ACIZE9_001111"
     CDS             20030..20518
                     /locus_tag="ACIZE9_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGC6092986.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20531..21478
                     /gene="prmA"
                     /locus_tag="ACIZE9_001112"
     CDS             20531..21478
                     /gene="prmA"
                     /locus_tag="ACIZE9_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGC6092987.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21479..22243
                     /locus_tag="ACIZE9_001113"
     CDS             21479..22243
                     /locus_tag="ACIZE9_001113"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGC6092988.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22476..24689
                     /locus_tag="ACIZE9_001114"
     CDS             22476..24689
                     /locus_tag="ACIZE9_001114"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HGC6092989.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24700..25146
                     /gene="dtd"
                     /locus_tag="ACIZE9_001115"
     CDS             24700..25146
                     /gene="dtd"
                     /locus_tag="ACIZE9_001115"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGC6092990.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25317..26576
                     /locus_tag="ACIZE9_001116"
     CDS             25317..26576
                     /locus_tag="ACIZE9_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HGC6092991.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26665..27612)
                     /locus_tag="ACIZE9_001117"
     CDS             complement(26665..27612)
                     /locus_tag="ACIZE9_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGC6092992.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28006..29298
                     /gene="hisS"
                     /locus_tag="ACIZE9_001118"
     CDS             28006..29298
                     /gene="hisS"
                     /locus_tag="ACIZE9_001118"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGC6092993.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29313..31082
                     /gene="aspS"
                     /locus_tag="ACIZE9_001119"
     CDS             29313..31082
                     /gene="aspS"
                     /locus_tag="ACIZE9_001119"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGC6092994.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31191..32066
                     /locus_tag="ACIZE9_001120"
     CDS             31191..32066
                     /locus_tag="ACIZE9_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC6092995.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32332..34215
                     /locus_tag="ACIZE9_001121"
     CDS             32332..34215
                     /locus_tag="ACIZE9_001121"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGC6092996.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34290..34574)
                     /locus_tag="ACIZE9_001122"
     CDS             complement(34290..34574)
                     /locus_tag="ACIZE9_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGC6092997.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34564..35298)
                     /locus_tag="ACIZE9_001123"
     CDS             complement(34564..35298)
                     /locus_tag="ACIZE9_001123"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGC6092998.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35427..36050
                     /locus_tag="ACIZE9_001124"
     CDS             35427..36050
                     /locus_tag="ACIZE9_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGC6092999.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36242..37363
                     /locus_tag="ACIZE9_001125"
     CDS             36242..37363
                     /locus_tag="ACIZE9_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HGC6093000.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37370..40498
                     /locus_tag="ACIZE9_001126"
     CDS             37370..40498
                     /locus_tag="ACIZE9_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6093001.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40517..43711
                     /locus_tag="ACIZE9_001127"
     CDS             40517..43711
                     /locus_tag="ACIZE9_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HGC6093002.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43857..44564)
                     /locus_tag="ACIZE9_001128"
     CDS             complement(43857..44564)
                     /locus_tag="ACIZE9_001128"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6093003.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            45329..45727
                     /gene="spxA"
                     /locus_tag="ACIZE9_001129"
     CDS             45329..45727
                     /gene="spxA"
                     /locus_tag="ACIZE9_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HGC6093004.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            46059..46712
                     /locus_tag="ACIZE9_001130"
     CDS             46059..46712
                     /locus_tag="ACIZE9_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGC6093005.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            46938..47936
                     /locus_tag="ACIZE9_001131"
     CDS             46938..47936
                     /locus_tag="ACIZE9_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HGC6093006.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            48112..49920
                     /gene="pepF"
                     /locus_tag="ACIZE9_001132"
     CDS             48112..49920
                     /gene="pepF"
                     /locus_tag="ACIZE9_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGC6093007.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        16177 a         8741 c        10454 g        14627 t
ORIGIN      
        1 tttattttga tgaatcagtt gtttcttcag ttgaagattc ttttgttgaa tcagttgatt
       61 ttgtgtcaga actctttgtt gaagctgtag tttcacttga gtctttcgta cttgatgaag
      121 ttgttgtgaa tgcactcaac acattttcaa aggcatcatc tttgattttt acatttgcat
      181 cttttaattc ttcaccgatt actttagttg tgaatgcatt gtcacttagt ttagtttcag
      241 tagcgatatc ttttagttga tctttgtatt tatccatgtc attgccttta ttttggtttt
      301 tcaccatttt gacaacgtag tattctgtcg cataagaagt aggatttgtt gtagtaataa
      361 catcggagat ctcaccgtct ttcaatttga aagctgcttc ttttacttct gcaggaatag
      421 ttgttgtcgt tgagtcgaat ttaactttac cgccatcttc ttttgtctct gtatcagttg
      481 atttgtcttt ggctaattta gagaaatcat ctccatcatc cgctgatttt ttcacatctt
      541 ttgcttcatc ttcacttgat aatttgatga tttgtgcttc tacttctgga tggaaagatt
      601 tccaagcagt tttcaaatcg tcatctgtaa tatctacgtg agctttcaag ccagcttcaa
      661 aagctaaatt gttacgaata tattctttat aagtatcttt cgtatatcca gcagcttcta
      721 attgtgattc aaaagtatca cctaatgatt tcgcttgttt gtcgtattct gcatccactt
      781 gcttatcggt tactttatcg ccatatttgt tattgaatac tttataaatg atcatccgtt
      841 gtactaagga ttggttcgat gattcaagtt ttgcttcatc atagaaatca gatacagtga
      901 tcgttccgcc tttcatcgtt gcgatatctt tattagtatc gcctgaacaa gctgctagag
      961 ttaaaacagc caacgcacta gtagctgcca aaataattga tttttttttc attaaaattt
     1021 gcactcctgt aattagttat tatttttata tattaactat accatatccc atttccttta
     1081 aaaacgttgt cgtggtagtt tcaaacaaaa ttcaaaattt catcacattc ctaggaaata
     1141 cgcaaacttt tctcacttat atagttaaat ctgttgagaa aataatcatt attatatttg
     1201 ttcaggatac tctggcagat cagcttttag tttttctact tgttcattga tttgtgtgat
     1261 acgtggttcg gcttggaatt taaaatcttc gatatctttt ttgattgctt cttggaaagc
     1321 aggaatcaca gattcagctg tttcttttgt ttcgatcaat gcgcttttaa aatgattcag
     1381 gctgttattt aaatcatttg tcagagttgt tgcttcttcc aattcttcga tcagtttctt
     1441 tcttgtttca ttcccgctcc tgggcgccaa taacagacct ccgacagtgc cagcagcagc
     1501 tccaaataac agtcctttga aaaagttttt aatcatcgca ggacacctgc tttacgattg
     1561 tttcttgaat agcttttagt tcttccgatc cataactatc ttgatgattg acaaagtgaa
     1621 tagaaaaatc atcctctttg ctgtagcgag ggactaaatg gatatgtgaa tgaaaaacag
     1681 attgataggc tagttcacgg ttgttattca agatattaag acctttcatt tctggaaaag
     1741 ctttttccaa tgcttgagca atcttaggca cacgcgaaaa aacctctcct gcaagttcgg
     1801 gatcatattc aaaaatatct gctacatgac gtttaggcac aactaatgtg tgtcctttcg
     1861 ttgcttgaga gatgtctaaa aaagcataga ccttgtcgtc ttcatatatt ttatagcttg
     1921 ggatttcttg attgatgatt ttgcaaaaaa tacagttttc catataaaac atcctttcta
     1981 taaagaataa atacttcagc ttaactttac cataagttaa agctattgta aggaaaaaaa
     2041 caaaataccg tcattttctt cgtggtataa taaataaaaa taaatggcgg aggaaaaaga
     2101 atgagtttaa ttatcgatca tgtcacaggg gggtacggac atctccctgt gttaaaagat
     2161 atcagtttcg atgtacagcc tggagagata gtagggttga ttggactgaa cggagcaggg
     2221 aaaagtacga ccatcaagca cattatcggt ctgctggaag cttcaaaagg aacgatagaa
     2281 atcaatcatc tatccttaaa gaaaaatacg gaagaatatc gcaaacaaat tgggtatatt
     2341 ccagagactc cttctttata tgaagaattg acattgagag aacatatcga agtcactgcg
     2401 atggcctacg atatacctat ggatatagca atgaaaagag cagaaaagtt gttggagact
     2461 tttcggttat ctaatcgtct tgactggttc ccagctaatt tttcaaaggg aatgaaacag
     2521 aaagtgatga tcttatgcgc ctttttgatc gagccttctt tatatatcat cgacgaacca
     2581 tttttaggct tggatccact agctatcaat gcattgcttg aattgatggt agaaatgaaa
     2641 aaagaaggag ccggtatttt gatgtctacg catattttag ctactgcaga aaaatattgt
     2701 gatcgttttg tggtcttaca taacggagag atacgagcag acggttctct tgagatgttg
     2761 agaaaagaat ttcagctgcc ggattcttct ttggacgaaa tctatattgc tttaacaaag
     2821 gagcaggcac atgagtagtt tttttcaaaa acgtttagca agacatcaaa agaaaatgat
     2881 gaaatatatg cgttatgtat tgaacgatca ttttgtttta gtttgtcttt tcttgattgg
     2941 cggtgtggga ttatattatt ctaattggtt gaaaaccctg cagccaccgt ttgcaattgg
     3001 agggctcata atctctgtat tttggatgct ctgtttattc gtgggtaaga tggctacttt
     3061 tgcagaggca gcagatattg tttttttact tcctaaagaa aaagaaatgc aaacctattt
     3121 ggaacgagct tttcgctatt cttgcatttt tccgttgatc tttttgatat tggcatgcgg
     3181 attggccatg ccattagtgg tggttagtac ggagcaatcc ttttcgatgt ttttcgtcta
     3241 tctgatcata ttatggagtt tgaaattcag tcatctgcaa atcaagagag cagaattgtt
     3301 tcgactagat caacaagtta ttcgttattg gaaattaggc tggttttttt cttctctgat
     3361 ctttttgttt ctatcatttt attggctaat atgggcagga atagcaggtg cattagtaca
     3421 ggcaagtcta tattactggt ttttgtggaa gcaacaagaa aaaggattgg attgggagaa
     3481 aatggtgcat gtagaagaac ataggttgca tcagatctat caatttatca atttattcac
     3541 agatgttcct gaaattacgg caaagatcaa aagaagacgc tatttggatc ctatattgac
     3601 tcatattaaa agagaatcaa aaaacactta tctttacttg tttgcaagaa gattggcaag
     3661 aggttctgat tttagtggtc tttatttccg attagtaatt ataggtgggt tattgattgc
     3721 cggagtagtc gacttttatt ttagtctgat tatcggtttc ttatttttat atttgatcgg
     3781 tttccaactg ttacctttag cgaaccagtt ccgctatatg gttctcgttc agctttatcc
     3841 aatccataag aatcagaaga agcaggcgat tcagtatcta ctcacatggg tattaattat
     3901 cgcgtcggtt atttttggtt tgattgctgc agtcgtatta gatgggcagc agcgatgggt
     3961 tccgctagcg gcttatttga ttgttactat gctctttgtt aaactatatg taccaactcg
     4021 tttgaagaag atgtcagact gaaaacaaag ctgtgtaggg taaaaatgag aatgaaaaat
     4081 agagcgttga cagtaagaat gctgttcgtt ctattttttt tgagaaaagc tggttttttg
     4141 aatggcaatt aaatgaaaaa gaacgtatat gtgcttgacg tgtagtgttc aggcgactag
     4201 aataataagt actgcaaaac aaagagtaag aggacgggag aatgcatgat ggagtttcag
     4261 ttagaccaag agtggcggtt acgtcccatc aaaggcgaca caggaaaaac atacataggc
     4321 atgcgtgatg aggacaaagt ctttattaaa cgaaacacga ctccgatgtt ggctgctctt
     4381 tcaagggaag gaattacacc aaaacttgtt tggacaaaac gaacggggaa tggcgatact
     4441 ttgacagcac aagagtggct ggaaggtcgc ttgctgactc ctaatgagat tggtcaaaga
     4501 aacgacgtga ttgatgtttt gtaccattta catcattcaa attctcttaa aaccatgctg
     4561 acccgtatcg gtggtcgtgt catgacgccg gagaagatgc tgcaaaaata tgaaaaagaa
     4621 ttaccggaag aactccagaa aaatcaattt ctgcaaattg tccatcgttt tcttcgtgag
     4681 cagatcccgt caatagataa ggaaaactta tcagtagtac acggagatgt aaaccatcgt
     4741 aattggttag tatgtaaaaa ttatttatat ctagtcgatt gggattcaat catgtttgca
     4801 gaccctgcgg tggatattgc aacgatttta ggaaattatg tgccactgtc tagctggaat
     4861 cagtggctga tcagttatgg catacgcccg actgacgaaa tgcttgaaaa atttcattgg
     4921 tatgcggcca tgaatttgct ccaagaaatc accagatatt gcaaacgtga agatcatcga
     4981 cggatgaacg aagaaatttt acaattaaaa cgaattttca gtggctgagg tttggcccaa
     5041 actctgcgga gatttggcca gaccttttta attagaggaa aggaatggag ataaataatg
     5101 cgtgtccgaa atcgtccggg agcagcggaa atgttagcgg ctcacccgaa ttttgtaatt
     5161 agtgatccaa cattgtggaa gggaaaatgg aatgaattgt ttgaaaacga tcatccaatc
     5221 cacattgaga ttggtatggg gaaaggccag ttcatcactg gaatggcaaa agcccatcct
     5281 gaaatcaatt atattggagt agaaatgcag gtcagtgttg tttcgattgc actagacaag
     5341 ttgatcgaac aaccgcttcc taacctgaaa cttctacatg tggatggatc agcgttgaca
     5401 gagtatttcg ctgacagcga agtagatcaa atctatctga atttttccga tccatggcca
     5461 aaaaaacgtc atgaaaaacg gcgattgaca tataagactt ttcttgctgt agatgaacag
     5521 attcttcgtc caaatggaga aatccatttc aaaacagata atcaaggatt gtttgagtat
     5581 tctctggcaa gtttttctca atatggcatg atcctcaaac aggtatggtt agatttacat
     5641 caaagtcaat ttgaaggcaa tattatgacg gagtatgaag aaaaattttc ttcaaaaggt
     5701 caacgtattt atcgagtaga agctcaattt caagataaga ccaaaaagaa aagtctgtga
     5761 aactaacttt ctgctttcat aaaaacatta atatccataa ataaatccca gaaaatgaac
     5821 attacagatg taatgtattt tctgggattt atttgattta aaatgtattt atttcatcgg
     5881 tttttccaca aggtggaatc aattggaagc gagaaaatga aaataatcct ttgtcggtga
     5941 tcttcaattc gggtatgaca gataatgtta agaaagaaag tgtcaaaaaa ggatcaaagg
     6001 ttttagctgc tcctagttga tgtgctttag ttattaattc attcaactgt tcatagacga
     6061 tcgaaaaagg ttcctgtgtc atgattccgc ctataggaag agaaacacaa gctatttcct
     6121 gctgattgtt gacaacggtc atcccgccac ctttttgaat caaaagatta gcagcataca
     6181 gcatatcctc gtcgtttgtc ccaacgacaa ctagattatg cgagtcatgg gcaatcgttg
     6241 tcgctatcgc tccttgtttc agctgaaatc ctttcactat gcctaatcca atgtttcccg
     6301 tttgatggtg acgctcgatc accgcaatct ttaattggtc tttttcgatt gaaggaatga
     6361 atcgttcgcc ttgtcggtcc actttttcta ccaaatcttt agtcactaga ctattcggga
     6421 taatttcgat cacatgggct tgtgaagaag aaagaagcag ctctaacgaa tgtggattta
     6481 atggttgagc gtttagtttt ggcagacaac acgtatatga atttgaatga tcagcaaata
     6541 aatggtcttg gagttgccca gattgaacaa ctaatgttcc cttatagaaa acttcatgaa
     6601 ttggcagctt ggtaagatcg tctgttaaga agaaatcagc ttgataccca ggggcaatcg
     6661 cacctagtgt tttcaaatca aaacattctg ctgcattcaa tgttgccatc tgaatggctt
     6721 gtaatggatc gattccaagt gcaatagctt gacggacgat atgatcgatt gatccttctt
     6781 ttactaaatc attgatcagt ttatcatcgg tgacaaagaa gcatcttctt gaattttcag
     6841 gtgtgatcgc cggtagtagc gatgccagat cttttgcaac ggtcccttct cgaaccatta
     6901 aatacatacc aagatccaaa cgttctttag cttcttttgc agttgtagct tcatgatccg
     6961 tccgaatacc tgctgcagga taaacattta actcttccat gccgatacca gctgcatgcc
     7021 cgtcaatttt tttcttatgc tggtgcatca attggatctt ttctaggatg tctgtttcat
     7081 tatttgctac tgcttgatag ttcatgactt cagctaagcc taaaacttcg ggtttttgta
     7141 aaaaaggggc taattttttt gcatttaaat ttgcaccatt ggtctcaaaa ggggttacag
     7201 gtacacaaga aggtagcata aaaaagatat tcatgagtgt ttgtcttgca tcttctatca
     7261 taaactcaag acctgtactc ccagcaatgt ttcctatttc atggggatct gtcactacag
     7321 tagtaactcc atgaagcaag gatacttttg aaaattcgct tggtgataaa agtgagcttt
     7381 cgatatgcac atggccatcg atgaatcctg gcactagata ttgcccatta gcattatgta
     7441 cgctttttcc ttcgtattca ccgattccta cgatcattcc ttcgcagatt gctacatctt
     7501 tttccatgat ttctttcgta aagacgttga cgatcttagc atgcttgatc actaggtcag
     7561 caggcttttt tttacttgct acttcgatat atttccttaa tgttgtttcc aatggagtgc
     7621 ctcccaagat aaatttttat aagtataaca taaattcggt ttttgccaat atttttttgt
     7681 aaattcattt tatttgaaac aaaaagatca aaaagacgta tgttttttgt ggaggggaga
     7741 ataatggaaa taaaacgatt atcggatcaa atgataagtg aaagttttgc caaacatgcc
     7801 caagacgtat atatattgcc agcttcagaa gtattttaca tctattttcg ctatggaaaa
     7861 aaacgaacat tctggaagaa agtctcttcg gcagatggac agcaactgat ctcaagattt
     7921 aagtatttgg gacagatgga tatcggagaa aaaagaaaag ctcagttagg tgcatttact
     7981 tattctttag aaaaacagga agttcgtctg cggttgtctt ctgtaggaga ttaccttcaa
     8041 cgagagagtt tagtgattcg gctattatac ggtacttttg aaacacccca tcgttgcttt
     8101 agttctcgag attttgcaac tattttacag aaaaccgtca gacgtggatt ataccttttc
     8161 agcggaccag tcggatcagg caagacttct ctaatgtatc ggttggcttt ggaagaaaaa
     8221 ttgcaagtga ttactatcga agatcctgta gagatagaag aaccgttttt tctgcagcta
     8281 cagatcaatc cgaaaatagc acagacttat gatacacttt tgagactcgc attacggcat
     8341 cgtccagact tgctaatcat tggcgagata agagatgaat caactgcaca tgctgcggta
     8401 agagcagcac taacagggca ccgggttttt gcaaccgtac atgcacgcaa tcttgaaggt
     8461 acattggtca gaatccatga actgacaaag aaaaaagaag agctatctga atgtttagct
     8521 ggtgtcattt atcaagaact tttggaagat gccaatcacc atccttctgt tttatggagt
     8581 tatcaattta tggaggaaga atcagtaaaa aaatcatggg aggaaagtta tgaagaagct
     8641 caggaaaata tttggcagtc agaactattc taaaggatta acaagaagcc agcaaaacca
     8701 gtttgcacaa accatgggag aactgctttt atctggtttt agtctgcaag aatcccttta
     8761 tttattactc acgatccgtt cgtttccacc tgttattttg gcaaatatcc aacatcagct
     8821 aaaggaaggg caagcgttta gtgaggtact ttcgcaaata ggatatggag cagagcaact
     8881 ggtacagatc gagttagctg aacgtcatgg gaatctgccg acaactttgt tggaaattgc
     8941 caaacagttt cggcttgttg aaggatttcg caatgatttg aaaaagctgc ttgcatatcc
     9001 gatgctattg ctcacctttt tgctaggtat cttgtttagt atgcggttgt tcgttttgcc
     9061 tcagcttatt ggttcaggaa tggtcatgca agagcattgg ggtattcagc tgatacaagt
     9121 ctttcattgg tatgttctac tattcatcct agcggttact ctattggctt tactagtaag
     9181 gtatcgtctg atgaagttgt ctcctgttga tcagagtgaa tggataagca gacaattatt
     9241 gattggaccg atatattcct tgtatcaatc ggcttatttg tcactagaga ttggaaagct
     9301 ttttcatgaa ggtttcgaat taaggcaaat catagtctgc ttaaaggaaa cgaaacaaga
     9361 aagtctgatt cagcatcttg cctctaagtt gattcaagga ttggaggcag gtatgtcatt
     9421 ggctgagcag ttccagaatt atcgttttct atcagaagaa ttcagtaaaa ttgttttaca
     9481 gggagaggca aagggaagtt taggtaaaga actgattttt tacagcgaat ggacaagaaa
     9541 acagcttttc aaacgtcttc atcactggat gcattttatt cagccaatca tttttttggg
     9601 cgtagcggct ttgattttat tagtttatgc cgctgtttta ttacctgttt acggaagcat
     9661 agaggaggtt ttgccatgaa aaagagaaaa atatcttatt atagcggttt tacattgatc
     9721 gaaatgctaa tcgtcttact gatcatcagt gtattagtgt tgttgttcgt ccctaatttg
     9781 tcgcgttata ggaatcatgt agaccaagaa agtcgtgaag cgatcatcca gttggtagac
     9841 acacaaaaag agctctatgc gcttcaaaat aatggaagag ttcctactgt ggaggaattg
     9901 ttgaatgaag gctatatcaa acgagaacat gcagaaatct atcagcggcc ttgaaggtaa
     9961 ggttttagca tcaggatata cgttgtttga atcactctta ctgattttat tacttacaac
    10021 gatcctttct tttccagttc tcgcattttc tgcatggaag aatgaattgg cagtctatca
    10081 atttttcggc caatttgaaa aacgaatcta ttctacgcaa aaaatcgcta ttgtgaatca
    10141 gatccaaaca ggcttttatt ggaatagtga agagaatcaa atcatttttc atgttccgaa
    10201 tccagataaa ataaattggg aagtattaga tattcctgat gagattacct tgaaacgcca
    10261 tgcttctatt acttttgctg ctagaaccgg gaatgaaagt tcactaaaag cttatcaatt
    10321 ttattgggaa gaaaaagagc ggacgattac gtatcaattc cagataggga gtggtcgcta
    10381 tacaaaaaga attgaataaa acaggatttg ttttgttgga gtcccttaca gcgcttatga
    10441 tcgcttctgt ctgtgtctac ttagtgagct ttggccagct gtttttgctt caggcagaaa
    10501 agaaaagtgg ggaggaactg ctatttattc gaatgattta tgaagatatc aagacgcagc
    10561 ggatgtatca caaaagacca gagcgaaggg aagaaatgat cccatacgat atccaaattg
    10621 tcgataataa tggagtaatc gaaaaagtgt ttgtcaatat ggagaaagaa gcgatcagta
    10681 ttgaaaaaac aagtaattcc agcatttacg ctgattgaat gtctaattgg actgatgata
    10741 ttgagcagtc tattgctcac attcaatctt ttgattcagc aaaccatcca agtaagtgaa
    10801 tttttgcagc gtaaagatca aaaagagtgg ctaatatttt tagcacaatt agaagaagaa
    10861 ctcaagagca gtcacaatgt ctctgtgaaa aatcagcaac tgcactacac gatcgaggat
    10921 aaacagtata tcatcgaaag atatcaggca atgatacgta aaagaagaac ttccggcgga
    10981 catcaaccta tgttaacaag tatcactgag cttcaattat tggaaaaaga acacacaatt
    11041 tctttttatg tacactttga aaatggagaa gatggatatg ccatatggac aaaaaacgat
    11101 cagtagaaaa tgttataagg gctctatttt attttctgtc ttgcttttat ttcttttatg
    11161 tacgttttta ttgatggcag cattagaaag ctaccgtttg tcaatggatc ttaatatacg
    11221 aatcaaaaat tattatatag caaaaataat gaagcagatg gctttatcgg aacagtctac
    11281 gcttgccgaa agttcggaag gagtttttta ctacacaact ggatctgtaa catatcagtg
    11341 ggtacaacag tccctattct tagaggtgga agtctcaccg tttatctttc ggttcacaga
    11401 agaagtaaaa aatgatacag atactagtac agaatgatgg aatgttcgtg aaaacgccct
    11461 cttttctgtt ataacactgt ttttaataaa aaaatgtttg ccgtttcaca aataaaaaac
    11521 agtgaaaacg attgaaattt tgtcaattgt tcgatagaat taaacaggtg aaaaaattgt
    11581 tataatatat ctagaaatga ggtgcaccat gttaccagaa aaaatggaac aagggtttaa
    11641 tcaaaacctg gaagctattc agcttttaca gaatgcattg ggaacttcct ttttagaagc
    11701 ctatgtcgaa aatgcagaaa atttaataga tgattatcaa gtacgtgtgg tggatggagt
    11761 gccgacaaaa gagacaacgc aacggatcac agctctttat gaagagttga agaaactttc
    11821 tttcgagcca gaagaatggc gcagactgtc tcaattactt ttattgaagg gcagccagac
    11881 agaacatttg caggcgaacc atcaactcac tcctgatagt atcggttttt tatttgtttt
    11941 tcttattgaa caactataca caaataaaaa agcaccggtt aagattctgg atattgcggc
    12001 aggaatgggc aacttgttat taacagttct tttaaaccta tcgaatgcgg ggtaccaaac
    12061 agaaggaatt ggtgtggata ttgatgatac attgttggct gtcgcagctt ctacaagtga
    12121 tttgacacaa gcaaatgttc aatactttca tcaagacggg ttgcaggaat tattaataga
    12181 tcctgtcgat tttgcaatca gcgatttgcc aatcggttat tatccgaatg acgaaaaagc
    12241 aaaagagttt ttaacaagta ccgaagaagg ccatagttat gcacatcatt tattgctaga
    12301 gcaatcaatg aaatatgtga agccggatgg ttttggtttg tttttgatgc cgagtggatt
    12361 tttagaaacg gatcaaagtg aagaaatcaa aaaatggttt aaagaagaag gttatcttca
    12421 aggaatgatt caattgccag atgaattgtt ccgtaataaa caatcgcaaa aaagtatttt
    12481 gatcttacag aaaaaaggac cacaagcaca acaagtaaaa gaagtcttgc ttgtgaaact
    12541 tgcttcatta aaagaaccag agaaggtgac ggaatttttc aacgagttta aaaactggaa
    12601 atcatctgct ctgtaatcat tcaacgagaa ggagagtcat atgtctaaaa caattgcaat
    12661 caatgctggg agttcaagtt tgaaatggca attatatcaa atgccagaag aaaccgtagt
    12721 tgcgaaaggg atcgtcgaac gtatcggttt acaagattct atttttacca tcaagtacgg
    12781 cgataatcaa aaattcgaac aaatcatgga tatcgaaaac cacgaagtag cagtaaaaat
    12841 gctgttagat cagttgattg aactgcaaat tttaagctct tatgatgaaa tcaccggagt
    12901 agggcaccgt gttgttcacg gaggagaaac ttatggggat tcagtagtga tcgatgagaa
    12961 agtaatggac cgcattgctg aattagcaga atttgctcct ttgcataatc ctgcaaactt
    13021 aatggggatc aaagcgttta aaaagatttt acctgacatt ttgagtgtgg ctgtattcga
    13081 tacatctttc cactcaacaa tgccaaagca aaattattta tatagcttac cggtgtctta
    13141 ttatgaagat ttcaaagtaa gaaaatatgg cttccatggc acaagtcatc gttatgtgtc
    13201 ggaacgtgcg gcaaaattat tgaacaaacc gatcgaagaa ctaaaaatca tcacttgcca
    13261 cttaggaaat ggtgtatcga tcacagcagt cgatggaggt aaatccatgg atacttctat
    13321 gggattcaca ccattagctg gggtgacaat gggtacacgt tcaggtgata tcgatccagc
    13381 tgttctccca tatttaatgg aaaaattaga gattgatatt gatgaaatga tcaatgtttt
    13441 gaacaagaaa tctggtctgc taggcctaac aggattgtct agtgatatgc gtgatcttga
    13501 aaagaactat gaaaaagaac atattcgttt agcttatgac attttcgtgg accgcatccg
    13561 aaaatacatc ggcggttatg tgacaacgat gaatggtgtt gatgcaattg tctttactgc
    13621 tggtatcggc gagaatgacg gacatgtacg tagtgaaatc atcaaaggta tgtcttggtt
    13681 tggttgtgaa atcgatccag cgttgaatga attgcgtggt gaagaagtag atatctctac
    13741 aaaagaatca aaagtaagag tattagtgat cccaacagat gaggaactaa tgattgcccg
    13801 tgatgtggag cgtctgcgcg gctaagccaa agcattcgtt aggataaaag atgaaacgca
    13861 tgcaagaggg aattcttgca tgtgtttttt ttgcggagaa gaccgcaaaa tggtaattta
    13921 acttcaattt cccttctttt ttacaggatc ttcttaggga attttgcttg gaaaagtggt
    13981 caaaagggaa aagactggca ttttatttat tgattttcag gaaaatccca atattttatt
    14041 ttcattcatc tttataaggg acattacata tgtaaaaaga aaaaacattt ttagatcagc
    14101 ctcgtgggct gtcgacttta ttcttcgctt tatgtttagc tagaaaaccg atccgaaaca
    14161 ttcattgatc gaataataaa aacttgattt tccacctgta ctttgcctga atcgtgaaag
    14221 cacaggtatg aaaatcaagt tttttgttgc gaaaaaacgt cctagtcaat cagttggccg
    14281 agcggctggc ggctgatctg ctcctgatca ataacgagtg cttcttggaa gtgttgctgc
    14341 aaaaagtagc ggtcatggct gactgctagg agcgttcctt gatagtcttg cagcatttct
    14401 tcaatttctt ctcgagcata gctgtcgagg tgattggttg gttcatccaa aatcaggacg
    14461 ttgatttttt ctaaaaagag tttcagcaac gccaaacgga ttttttcacc accggataaa
    14521 tctttgatcc gtttacccac atcgctttga taaaagccac ttttggctaa ttgccgtcga
    14581 gcgacttctt cgtttccagt caatgtgatg gcgtaagcca gcaaacggct atcgggatcg
    14641 gcaaactgca gctgctgcgg caaataaccg atttgcaagc tactacctaa tttgatggtg
    14701 ccaccgtaag gcttttcctc accgagtaat aatttgagta aggttgattt tcctgcacca
    14761 ttgtcgccga tgatggctaa atgatctcca cgatagactg caaaactgct gtctttgaat
    14821 agtacttgat cagcgtactg ctggtgcaag ttttgaatga tgaaaacttc tttgccagat
    14881 tttccaccat tagacaagct ttgcagccga tttttcgggg gaggtggcgg tttgacgagt
    14941 gtcagtttcg ccaggcggcg ttccagttct ttggcttttt tgaagaagga ctcattgtct
    15001 ccttcatgtg cccactgacg aaaacgacga atcatgactt tcaaccgctg gacttctttt
    15061 tgctgcagtt cgtaattttt tgtcagctca gccaagcgag cttctttcaa gactcgaaaa
    15121 cggctgtagt ttccgggata ctcaatcaat gcaccttctt ccagttccca tgtttttgtg
    15181 gtgacttgat cgagaaattg ccgatcatga gaaacgacca gaaccgattt ttttgtattc
    15241 tgtaaatagt tttccaacca gcgaatactg ttaagatcta aatgattggt cggttcatcg
    15301 agtaaaagta aatcggcatc ggctgctaaa attttggcta aagcgacttt aactcgttcg
    15361 cctccgctaa gttctgttaa ccgtgcttcc tgacggtgtg gaatccctaa gccttgcaag
    15421 atcgctgcaa tccggtcttc taatacgtaa ccgcctagtt cttcaaagcg atgctgcagc
    15481 tcaccgtaac gggccagaca cttctctaag tttgtatctg gttctgtcat caatgcttcg
    15541 tagcgactca tttgctgttt gaggtcctgt atctcagcgg cagaatggag caagtagtgg
    15601 ttgacggtcg cttcggaaac tgtaagttct tgttcgaccg tcccgatctt taagcctttt
    15661 ttgcgactga taacaccgct gtcgacacct tctctgccgg tcaagatttg taaaaaggtt
    15721 gatttgccag ttccgttgat accgactaag acaatttttt caccagcttc aatttgacag
    15781 gataaatcct caaataatgg attcccgccg attgtttttt taatagaaat tgcttgtatg
    15841 atcatgatct ctctccttga gaccactcaa aaaggccatg gttatccatg gcctgtgtta
    15901 tttaaactca gattatcatg agaaaaatac cttgagatgg ccattgattt tacgtgaatt
    15961 caactgtttt ggacaaactt gtcccgtcaa cagcaactgt aaaaccaatt gcatggctaa
    16021 atgcgatatg gtatcgttgg taattttcat tacttgttat tttagtcatg cgcatcatag
    16081 tattttccct ccttcgtgta gttgtctttt ccagtgtacc tgaaagtgtc agaaagttca
    16141 actagcgctg acatttactt aatatttatc gatgtgtaat tctgtcagag agcttttttt
    16201 atctgactga gggtaatgtc tcgtggacca catcattgta ttctgagcta aaccagcgtt
    16261 caggcgaaat catatggtgt ttgataaaaa actttgtcta catgacttcc ttttgccatt
    16321 tgcttaatac cgttgcatta aacagctctt ctctttggaa atctcaccaa catcgcgttc
    16381 aggagtatcg ttgtggttgc aatggcaagc ggtagccttt catcaattct tgaatgattt
    16441 accgaatgta gcacttgcct tctcgcggta cccgaacccg aaataaaatt ttagtttggc
    16501 gataaaatcg gtatccgcca tcgatacttc atattttttc gtatcagatt catcggaaac
    16561 ttccacattg acgaaccaat aagctttggc atgcttaggt cgttttaaac cacaccaggg
    16621 cgactaatcg ccctggtgtt cacttttttt tattttactt gaactcattg actgttttcc
    16681 ctttatttta aacattataa agaccgatga gtgcttgccg cgtcttttgt ttttatcacg
    16741 gttttttgtg caaaaaaacc tgccgatagt tggcaggtcg tctacgtgtt aagctttggt
    16801 gtggtcttta gctggcaatt ggttttctaa atcagttcgg acaacaagca catcgcaagc
    16861 tgcgtttcta ataacatatt cagaaacaga accaataaat aaacgttcta cagcattcaa
    16921 tcctgtggct cctaacataa tcaaatctac ttgattatct tctgggattt ctctggcaat
    16981 aatttgtttt ggtgagccat attctacgac agaggttaca ttattcaagc cagctttctt
    17041 cgcattgctt tcataatctg ccaatgtttg ctttgccatt tcagtagctt gttctgcaag
    17101 cattccatca aaggatgaaa cggtttggaa agaacgtgtg tcaatgacat gtgctaatag
    17161 aagttctccg ttatttcgga tagctacatt gaccgccttt ttaaaagcta attcagcttc
    17221 atcagaacca tctacggcaa ccatgatttt tttgtattgt tgtaacataa gcattcactc
    17281 ctcaagtcaa tcgtattgta ctcttttatt gtagaacact ttagggaaaa agagaattat
    17341 ttactgcttt ggttcagcaa ttttttttgc aaatcggata ctgaaggtgg cagaaacaat
    17401 aattacgatc agtaaaaaga ccaaggcaat aaagcgttga ttgaaaaaag ctgttaaaat
    17461 acccattacg cctaaaacag catatgcagc tccgtaaaat tgtaggaatc cttgattttt
    17521 atcatttttg ttgatcaata caaaaaagat atcctgttta ttaaataaat aatagctaac
    17581 gaataataat actaaagtgg cgataatcat taaaatccta atcatgaaca aatcctccaa
    17641 aataagcaac aaatagaaaa agcaatttgc caagagcaaa ttgctttatt ctttaaaaga
    17701 tggtaatctc cgttaatgcc gttgtttgtc ctgtagtatt gatcccgcga attcaagcag
    17761 gtgggtccca tggtcgtagc ttcgaactac caaatgataa ggcatgttac cagcagtgac
    17821 acaagacggg tcccaagata tcaataaaaa tgttcggtca acacacaaag aggacaattc
    17881 gaacatcaca gatttcccac ctctatagta gcatatgaat ttaaaaagag caatgagaga
    17941 gctcgcagaa acagaaccgt tttcttgtct agttttttgg aggatgcttt ttccactctt
    18001 ttatacggta atactgttga cccagagcct gttcatattt ccctgtatct tttggctgat
    18061 aatactgagc attcttcagt ttatctggta aatattgctg attgacccaa gcctgatcaa
    18121 aatgatgagg atactgataa cccacgccac ggttgagtga tttcgcacct ttgtaatggc
    18181 tatctctcaa atgatcagga acatctccag ctttgccctc tcgaatatca gcaagtgctg
    18241 catctaatgc catgtaggca gaattggatt ttggcgacaa gcaaagatcg acgacgacgt
    18301 ctgctagtgg gatacgtgcc tcaggcaatc ccaatttttc agcagctaat acagcgttca
    18361 ctgtacgagc cgcagcagca ggattaccta aacctatatc ttcataaccg ataaccatca
    18421 gacgccggca aatacttgcc agatcacctg cctcaactaa acgggcgaga taatgaagtg
    18481 cagcatccac atcacttcca cgaatcgatt tttgaaaagc cgaaataacg tcataatgag
    18541 catctccatt tttgtcatgg gtaagagctt ttctttggac acattcttca atgatcgaca
    18601 gtgtaagatg aatccttcct tctttatctg aaggagtcga tagtgtagcc agttccagcc
    18661 cattcaatgc actccgcaaa tcgccgttcg ttgcacgcga aaggtgaaga agagcatctt
    18721 cgtctaactg gattgcttgt tgtccaaggc cgcgttcttt atcccttaaa gcatgttcga
    18781 ctgccaactg gatgtcttgt tctgttaatg gtttgacttc aaagatctgt gtacggctgc
    18841 ggatcgctgg attgatggta atataaggat tctcagtagt cgctccgatc aagatgattc
    18901 ggccactttc taaatgagga agcagaaaat cctgttttgt tttatctaat cggtgtactt
    18961 catccaataa gaggatcact gtaccactca tttttgcttc ttccgctaca acttgtagat
    19021 ccttttttga atctgtagcg gcgtttagca tgcgaaatgc ataattagta gagccggcga
    19081 tcgcacttgc gatactcgtt tttccagtac caggaggtcc atatagaatc atggaagaga
    19141 gcatgcgagc atcgaccatg cggcgtatga tttttccttc cccgactaga tgctgctgac
    19201 caacgacttc atcgatcgtt cgaggtctca tgcgataagc caatggctgt tgcataggat
    19261 tttcctcctt cttgttttta cgtcccttaa ttatatcata tttagcaaga tgcctagaaa
    19321 gaacagcctt ctgttgtttt gttttcatag cttatccaac taatattgtg tatgataaag
    19381 taggtgagaa aaatgacgga taaacaaaag atagatgaat ttttttggaa taaaacgacg
    19441 ccagaagtgg cacgggattt attggggatg tatttggagc atgacacacc agaaggaaga
    19501 ttagctggat atattgtaga cgcggaagca tacctaggtc cagaagacga ggccgcccat
    19561 agctatggtt taagaagaac accgcgtgtg cgggcaatgt atgaaaaacc aggtacgatc
    19621 tacctttaca cgatgcatac tcatcggatt ttgaacatca ttactcagcc agaagggatt
    19681 cctcaaggag taatgatacg tgcaatcgaa cccgccgcaa tgattgatca aatgagtaaa
    19741 aatcgtggcg gaaaaactgg tccagatatc agcaacggtc cgggaaaatt agtggaagca
    19801 ttagcaattc ctcaagaact ttatggtcag tctatagcag atagttcgtt acgcttagtt
    19861 tttgagaaaa aaaagacacc aaaaaagatc aatgctttgc ctagaatcgg tatcccaaac
    19921 aaaggtgtat ggacagaaaa gccgttgcgt tttgttgtgt cgggaaatcc ttatatctct
    19981 ttacaaagaa aaaaccaaat cgagaaagat tggggttgga ggaaagaaaa tgaaaaagaa
    20041 ggatctatta acatatttag atgaaataat tgaaaaacaa gtgacagact atgatgtagc
    20101 tttagattgg gatacaaaaa atcatacgat cgagatcgtt gttcgcttgt ttgcagaaaa
    20161 taaagcacaa tttgagattg atgatgcaga agggatcgtt tcgcaagaac caattatcga
    20221 atttgaagac ggcgtacttc tttttaatcc tcagaaatct gtttttgatg aacgcaatta
    20281 tctagcagta atcccttatg aaggaaaaaa agggttggca aaatcagtag ctgattcttt
    20341 agtggaatat ctaaatgaag tattagctca agggcaaagc gatttgcttg attttttgga
    20401 tgaagacgat gacgaagctg tattcgagct tcactgggat aatcagcaac tagcagaatt
    20461 agtagaagta aaacagcaaa atgaagcaga tacttattta ccgtacccaa gttattaagg
    20521 agtgacagat atgaaatgga atgaagtaaa agtagaaact gaaagtgaag cagtcgaagc
    20581 agttgctaat attttgatgg aggcaggggc gagtggtgtc gcgattgaag attctttaga
    20641 tgttgaacat tttcagtcgg atcaatatgg tgagatttta gataaaaatg attttacatc
    20701 gctgaaagaa ggcgcactag tcatggctta ttttccggaa acgactttct taccggaaat
    20761 cttgcctttt atcaaagatc gtatcacaca attacctgag tttggtctag ctattggaaa
    20821 aaataaagta acagttagtg aagtagagga aagcaactgg gcaacagcct ggaagaaata
    20881 ctatcatccg gtgcgtatta cgcgaatgct gacggttgcg ccaagctggg aaaactacca
    20941 gacagaagat cctctagaaa aaattatcac actagatcct ggtatggcat ttggcacagg
    21001 cactcatccc acgacttcct tgacattgac agcactagaa acagtcttgc gtggtggtga
    21061 aacattgcta gatgtgggaa ctgggtcggg cgtgctaagt attgcagcaa aatatcttgg
    21121 tgcaaaagat gtctatgcct ttgatttaga cgaagtagcc gttcgttcgg cgaaagaaaa
    21181 tatggatatg aatgaaatag ccaaagatgt ccatgtatca gctaacgatc ttttgacagg
    21241 aatcgagatt gaaagtgatg taatcgttgc gaacatttta gcagatatca tcttattgat
    21301 gatcccagat gcttggcgtt tactgaagca aacaggcacg ctgatcgttt caggaatcat
    21361 tgaagagaag aagcaaatgg ttctggatgc catgttagaa caagggttta tcgtggatca
    21421 aattttccag caaaaagact ggtatgcaat tattttgaaa aaaccagagg tggaatagat
    21481 gcagcggtat tttttaaaag aatcatatga atcaaaagac tattttgttt tagaagggga
    21541 aaactatcac cacattgtac gggttatgag gatggaaccc gaggatgaag tttttttggc
    21601 attcaatgat caaatagcca ttgttgcaga aatcacggag attactgaag aggctgttta
    21661 tctgaaagaa attaaaaaag aagaaaatca aaaggaactg ccaagttcga ttaccatagc
    21721 gagtggctat cctaaagggg aaaagctgga ttggatcgtt cagaaatcca ctgaattagg
    21781 agcgcaagct tttcttggtt tcccggcatc agcctctgtc gttaaatggg atgcaaaaaa
    21841 acgtatgaaa cgacaacaac ggcttgaaaa gattgctcaa gaggcagcgg aacaatccca
    21901 tcggcagatc gtgccatcag tagagttatt ggaaacgaaa caagatttat ttgagcggct
    21961 agatgattat gacgtggtct tggttgctta tgaggaatca gcaaagcaag gcgaaaaatc
    22021 aaatgcagcc aaaattctta gtgaaacaaa accagatagt cgaatcttag ctgtctttgg
    22081 accagaaggt ggattatccc gcgatgaagt cgattatttt gtagaacaca aagggatact
    22141 ttgtggatta ggaccaagaa tccttcgtac agaaacagca cctctttatt tattaagtgc
    22201 tgctagctat caatgggaat taatgaatcc ttctttcagc taacgttctt cattaataaa
    22261 agagtatcga cagaaagaat tgaaaaaata gtcaacaatt tgtataatag aaacaattat
    22321 ttatacaatg gatacgaaaa atcgtttgaa aaagctttta aaaagcgaac atttccgtaa
    22381 aaaaacgtat aactgcacgg attttgggac aattatcaaa cagatatttg tcccgattcc
    22441 cgttttaccg aaaaaagaaa gggggatcga ttcctgtgac aaaagaagaa attttaacgg
    22501 gacccggtgt cataaagctc gttagtcaat acatgggtcc cgaacatgta gcatttgttg
    22561 agaaagcatg cgaatacgcg actgctgcac atgacggaca gtttagaaaa tcaggcgaac
    22621 cctacattat tcatcctatc caagtcgcag gtatattagc agatttaaaa atggatcccc
    22681 atacagtggc tacaggcttc ttacatgatg ttgttgaaga tacagaaatc actttagaag
    22741 atctgagaga agaatttggc gatgacgttg ctatgttagt ggacggcgta accaaattag
    22801 ggaaaataaa atataaatcc cacgaagagc agctagcaga aaaccaccga aagatgctgc
    22861 tagcaatggc tcaagattta cgagttatca tggtcaaatt agctgataga ctacataaca
    22921 tgcgtacgtt gaagcacctg cgagaagata agcaaagaag gatcgctcag gaaactttag
    22981 aaatctatgc gcctcttgca catcgtctag ggatcagccg gatcaaatgg gaattagaag
    23041 atacagcact tcgttatcta aatccaaaac agtattaccg tatcgtccac ttgatgcaga
    23101 cgaagagaga agaacgtgaa aaatacgtaa gtggtactgt tgaagatatt cgaatagcga
    23161 cagaagagct ggggattttt gcagaaatct atggacggcc aaaacacatt tattcaatct
    23221 atcgtaaaat gaaagatcag aaaaagcagt tcaacgaaat ttatgacttg ctagctattc
    23281 gagtgatcgt agattcaatc aaggattgtt atgctgtatt aggagcaatc cacacaaaat
    23341 ggaaaccaat gcccggcaga tttaaggatt atattgccat gccaaaagct aatatgtacc
    23401 aatctttgca tactaccgtg atcggtccgg caggaaatcc ggtagaaatt caaatccgaa
    23461 cacaggaaat gcatgaaatc gctgaattcg gggttgctgc acactgggcc tataaagaag
    23521 gaaaaaatga aaaagtagaa ccagatggta tgacgaaaca attaagctgg ttccatgaga
    23581 tactcgaact tcaagacgaa agctatgatg cttctgaatt tatggaaggc gtaaaaggag
    23641 atatctttag tgataaagtc tacgtcttca caccaaaagg agacgttact gagttaccaa
    23701 aaggatccgg accattggac tttgcataca gtatccatac agatatcggt aacaaaacca
    23761 ctggtgcaaa agtaaatggc aaaatggtgc agcttgatta caaattgaaa aacggagata
    23821 tcattgagat catgacttct ccaaattcat ttggcccaag tcgcgactgg ttgaaattag
    23881 ttgctactag caaagcaaga aataagatca aacgtttctt caaagcccaa gatcgagaag
    23941 aaaatgtgat caaaggccac gaatccgtgg tcaaatgtat tacagatcta ggatttacgc
    24001 ctaaagatat tttgacgaag aacaaactgc aagaagcact cgatcgtttt aattatcaaa
    24061 cagaagatga tctctatgca gctgtagggt atggagaagt tagccccttg acgatggcca
    24121 atcgtctgac tgaaaaagaa cgtaaagaac aaaaaatcga gcagcaaaag caagaagcag
    24181 aagaaatcat gaatcagccg aaaaaagaac ctgacaaaat gaaagtacgt catgaaggtg
    24241 gcgttgtcat tcaaggggta gaaaacttac taattcgtat cagtcgctgc tgtaatccga
    24301 ttcctggtga tgatatcgtt ggttatatca ctaaaggcag agggatatcc attcatcgtc
    24361 gagattgtcc gaatgttcag cctgacaaac caaatgtagc agaacgtttg attgaagtcg
    24421 aatgggaaga tacatcgaat acacgaaaag agtatgatgc agatttggaa atttacggct
    24481 ataatcgttc aggcttattg aatgatgtac ttcaaacagt caatgcgcta acgaaaaatc
    24541 tcaacagcgt tgaagcacgg acgaataaag ataaaatggc gacgatccat ttgacggttg
    24601 gtatccagaa tttatcccac ctaaagagta tcgtggataa aatcaaagca gtacctgatg
    24661 tctacagtgt acgccggacg aatggatagg aggacagata tgagagcagt tgttcaacgg
    24721 gtaagtaaag ctgctgtgtc agtcgatcag caagaaattg gaaaaattgg ctacggccta
    24781 cttgttttat taggcattca tgaaaccgat acgcaaaaag atgtggacta tctggtaaaa
    24841 aaaattgcac aaatgcgtat ttttgaagat gaacaaggaa aaatgaatat tagtgtagaa
    24901 gatgtgggag gacaaatttt aagtatctct caattcacac tgtttgcgga tacgaaaaaa
    24961 ggaaatcgac caagctttgt ggaagccgca cgaccagaaa cagctattcc tttatacgaa
    25021 tcattcaatg aaggaatcag aagtcgcggc atcacagtcg ctaccggaca attcggagca
    25081 gatatgtcgg tttctctcgt caatgatgga cctgtaacga tcattattga ttctaaaaac
    25141 aaataaagta atctggtttt cactagtaaa aactatgaaa cacgtcgctt aagttagact
    25201 gataaactct aacttaagtg gcttttttgt ctgcaaaaag cgcttctttt gtcagcagtc
    25261 ggaaaaaaag ttaagcttaa attatacaag ttatttttta taggaggttg ctgaagatga
    25321 aagaagtacc agtagtagat atcaaaatca cagatttaaa aaaattgtat caaaaaggat
    25381 acaacatgtt ggaggagtta cgccatgaag cggacgctcc cgtcgtcaaa gcaaagattt
    25441 tcaataaaga agctatcacg atctacggat catcagcagc aaaagtattt tatgatccaa
    25501 ggaatttcaa acgaaaaggt gctatgccaa aattagtatt gaagacactt tttggtcaag
    25561 gtggagtaca gactttggat ggagctgctc atcaccatcg gaaaaatatt tttatggatc
    25621 taatgacacc ggaaagaatg gaagattatc atcgtatctt agataagaat ctgacacaag
    25681 cacttgaagc acagcatggt caatttgaac tatttgattt aagtaagatg gttttcttta
    25741 catctatttg cgagtgggca ggtatcaatt tatcagcgat ttctaaagat gaggtcgaaa
    25801 aattagcaga atatcaaatc tctatgatca gcggaacgtt tacttctccg attgatcaca
    25861 taaaaggtgt cgaaaatcgc aaaaaatcag aaaaatgggc gcaaggcttg attgaagaag
    25921 ctcgacaaaa tcctgtggct ggaaaagaaa atgtggcatt atatgctttt gccaatgcca
    25981 cagatttaga tggtcagctt ttacctctgg aagtggcagc tgttgaatta ttgaacatca
    26041 tccgtccaac ggttgctcta actgtgtggg cggcattgat gggacatgca cttttcagta
    26101 gaccagattt gtatcagcaa ttaaaaaatg acttttcgac gttacaagat ccgtttattc
    26161 aagaaatgag acgctattat cctttcttcc caatgctacc tgcgatttcg ctgaaagaag
    26221 tagaagtaga tggttatcgt ataccagaag gcagttgggt tattttagat ttatatggaa
    26281 cagaccatga tgaacgaaca gttgaagcgc cagattcctt tatgatcaaa cggtatgtag
    26341 ggaaagcaaa agatatttcc tataaagaag aatatgagat gattgcacaa ggcgggggaa
    26401 attttcgaca aatgcatcgc tgtgcaggag aatggatcac tcttcatagt ctacgtgtgt
    26461 tttccgatca gctagtaaat aagtttgagt tctctgtacc tgaacaagat tggacgattc
    26521 cattcaatca gtttccgact tatccgaata gccgagcgct actttacaag aattagatta
    26581 gcataaactt atcgaaaaaa aggaagatca aacagtgctg atcttccttt tttcatatta
    26641 ctataaattg ataaggtcaa ttgatcaaaa tccacgaaat gcttcatcaa tggtttgata
    26701 atcttcattg gataaatgca aatctaaagc ttggacattg tcagatactt gctctggacg
    26761 cttagctcca ggtataacta cagacactcg tggattcttc atgtaccaag ctaaaacaag
    26821 ttgcgcagga gtggcttggt atcttttagc aatggggcga agtacatcga cagcggttaa
    26881 aatttctctg aaacgttctc cttggaaatc tggatttctt tttcgaggat ctccttcacc
    26941 aaattgtttt tcctcaccaa gttcatattt tcctgtcagc aaaccggaag caagaggaaa
    27001 atagggaaca aaactgattt tgtttttttc aagataaggg aataattctt tttcagcctg
    27061 ccgatggatc aaactgtatt tatcttctac tacatcgaca tatccatctg cattcgcttc
    27121 tttcaattgt tctaacgtga agtttgacac accgactgct cggatttttc ctgcttcttt
    27181 taattcgtgc aatgtagcaa ctgattcatt ttttggtgtg ctttcatccg gaaagtggat
    27241 ataaaaaatg tcgatgtaat cagtttgcag acgttttagt gcatcttcca ccgattgttt
    27301 gagaaactca ggagaattat caaatgttcg ccctttattt ggtacatgag cagcttttgt
    27361 agcgatgacg acacgtgagc gatcatattc tttttccttc agtacctcgc caatcagttc
    27421 ttcggaacgg ccgtttccgt aagcataagc ggtatcgatc aaattgatcc cgctattcaa
    27481 agctgtacga actacttgtt ttcctgtctc atcttccaaa ccgtcaaaaa gattatgtcc
    27541 tccaacggca tttgctccta atccaagctg ttctgcgtag acttgtgaat gtccgattct
    27601 tatttctgcc atagctgatt cctccttttt gtctagtcta aaacaaaata ccaaaaagct
    27661 gaactaaaac gtttttgtga ggggaaatag tcagatatct cttgactttg agactggttt
    27721 ttagtaggtt ataagtaata tcgaatgtca atgaaagagc gagtaagttt ttgaaacttt
    27781 acaagagagg atcatcgagg ctgaaaatga tctaaagttt cattagccta aagacactct
    27841 ggagatggac gagtgaaaag ccgtcccgcg tacgagcgtt attcgtaaga ggaaagagaa
    27901 atctttcaaa attaggtggt accgtgtatg aatttcattc acccttgttc atgatgaaca
    27961 agggtgattt ttttatttac atagctaaga aagggagaga aaactatgag tttccaaaga
    28021 ccaaaaggaa caaatgatat tttgccaggc gaatcagaaa aatggcagtt tgtcgaagaa
    28081 acagcacgtt tattattcag agattatcag tataatgaaa tgcgtacacc gatttttgaa
    28141 cactatgaag tgatatcccg aagtgtaggg gatacaacgg atatcgtttc aaaagagatg
    28201 tatgattttt atgacaaagg ggaacgccat gtgacgcttc gaccagaagg tacagcacca
    28261 atcgttcgtt cttttgttga gcataaattg ttcggcccag agtatgcgaa accgttcaaa
    28321 actttttata tgggaccaat gtttcgctac gaacgccctc aaaaaggacg gttacgtcaa
    28381 ttccatcaaa tcggagtaga agcatttgga tcagaaaacc ctgcaactga tgtggagagc
    28441 atggtgatgg cacttgattt cttcaaacag ttggggatca cgcaaatccg gctagtcatc
    28501 aattcattag gtgataaaga aacgcgtcaa gcctatcgtc aagcattgat cgactatctt
    28561 ttaccttttg aatcagagct gagtgaagac tctaaacgcc gccttcatga aaatccatta
    28621 cgcgtattgg acagtaaaga caaacgagat caaaaatttg tggcagaagc tccatctatc
    28681 ttagattatc taagcgagcc tgctcaaaaa cattttgata ccgttgtttc catgctggat
    28741 gcattggctg ttccttatga aatcgacagt aatatggttc gcggactaga ttattacaca
    28801 catacgattt ttgaaatcat gagtgacgca ccaaaaatgg gggcacaagc aacgatttgc
    28861 gcaggcggac gttatgacaa tctagtggaa gaactaggtg gtccttcaac acctggcttc
    28921 ggatttgcaa tgggtatcga gcgattactc ttgactatgg aggcagagga agtagttatc
    28981 cctgcattta atgagttgga tgcttacgtg gtcgcactcg gagacgaaac aaatatcgaa
    29041 gcattgaaag tggtccaagc gattcgaaac tttggttttt cagctgaccg cgacttcatg
    29101 aaccgtaaag caaaagcgca atttaagaca gcagataaag cgaatgccaa attagtattg
    29161 gtgatcggtg aagatgagct tgctagtcaa acgattaatg tcaaagcaat ggcaagccga
    29221 aaagaaaaaa gttttccatt agaagagata tatgaacatt ttgatgaagt ctatgatgaa
    29281 atgactttat tcgagtagga ggaaaaaaat aaatggcaca aagaacgatc tattgcggat
    29341 tagtttccga acaacaatta gaacaaacag ttacattaaa aggatgggta caaaaaagac
    29401 gagaccttgg gggagtaatc tttatcgacc tacgtgatcg tgaaggaatc gttcaaatcg
    29461 tctttaatcc tgaaatcaac aaagaagcat gggaaatcgc ggataaatgt cgcagtgaat
    29521 acgtgatcga agtgactggg gaagttagaa gacgcggaga aaatgcagta aatcctaaaa
    29581 tggccactgg tgaattcgaa gtgattgcaa gtgaaatcgt gattttgaat caagcaaaaa
    29641 ccccgccatt tcaaattgaa gatgatcaag caatcagtga cgaaatacgt ttgaaatatc
    29701 gttatttgga tctgcgtcgt ccaaaaatga ctaaaaacat caaattaaga aatgcgacaa
    29761 caaaagcgat tcgtcattat ttagatgata atgactttct cgatatcgaa acaccttacc
    29821 tagggaaatc tacaccagaa ggcgcaagag actacctagt tccttcacgt gtccatgctg
    29881 gacatttcta tgcgttgccg caatctcctc aattgtttaa acaattgctg atgaatgctg
    29941 gattcgaccg ttattatcaa atcgttcgtt gtttccgcga tgaagattta cgtggagacc
    30001 gtcagcctga atttacgcaa gtagatattg aaacaacgtt cttaacagca gaagaaatcc
    30061 aaacttacac agagggattg attgcgaagg taatgaaaga agttcgcggt atcgaagtca
    30121 cattgccatt tcctcgtatg acctatgatg aagcaatggc tcgctacggc agcgacaaac
    30181 cggatacacg ttttgatatg gaattgatcg atctaagcga tacagtcaaa gaagtagaat
    30241 tcaaagtctt ccaaatggct cttgaaaacg gcggtgtcgt gaaagcattg aatgctaaag
    30301 gcgctgcaga tcgctactca cgaaaagaca tggatcagtt aggtcaatat gtaggacaat
    30361 tcggagctaa ggggcttgca tggctgaaag tagaagaaga cggattgaaa ggtccaattg
    30421 ctaaattcat gggagaagca acagaagcaa tcattaaagc aacagatgca aaaccaggtg
    30481 acttgctgat gtttggcgca gataaaagtg aaatcgtcgc tgctgcatta ggtgctatcc
    30541 ggacacgttt aggaaaagaa ttaggactaa ttgatgaatc gaaattcaat ttcttatggg
    30601 taactgattg gccacaattt gaattttcag aagaagaagg tcgatatgtc tctgctcacc
    30661 atccattcac gatgccaaaa gaagaagata tcccgttatt ggctgaagac cctgcaaaag
    30721 tctatgcaga agcttatgat atcgtcttga acggttatga actaggcgga ggttctatcc
    30781 gtattcatac tcgtgagctt caagaaaaag tactagaaac tctaggcttt acaaaagaac
    30841 aaatggaaga acaatttggt ttcttgttaa cagctttaga ttacggattc cctccacatg
    30901 gcggtattgc attaggattg gaccgttttg caatgttatt agccggagaa gataatattc
    30961 gtgaagtcat tgcctttcct aaaaacggaa aagcagcaga tgtgatgagt gatgcaccaa
    31021 gtatggtttc gcctttacaa ttgttcgaat tgaatattga tgtaacgaat atagaagaat
    31081 agccgataaa aaggtaaaaa ggatttgtcg aatacgcttc ttttgacaac cttgatttaa
    31141 ttgaaaaaca ctttataatg aagccataac atataaagcg gggcttttcc atgaaaaaaa
    31201 cattcgaaaa ttgggcttat catgattaca cgaccaagct ttcggtatct atcgtttatg
    31261 cgttgatcgc atcagtcgca ttgaatttct tttatcagcc aggacatatt tattcaagtg
    31321 gtattactgg tctagctcag attttgacga ctttgtcaaa atcactgata ggattcgaag
    31381 taccggtatc aacaactttg tatttactga atataccttt gtttgtattg gcgtggttaa
    31441 aaatcgggaa gaagtttaca attttcactt ttatcacagt cactttgacc tccctttgta
    31501 tccatatttt accggaaaca gtcctatcta ccgatccaat catctgtgcg ttgtttgggg
    31561 gggctgtgat gggactaggt attgggctag cgttgagaaa cggcctatca tcgggcggtc
    31621 tagatatcgt gagtatcacg attcgtaaaa aaacaggaaa gtcgattggt tctatttcga
    31681 tctacttcaa tgcattgatc gtttttgttg ccggaattct atttggctgg caatatatgt
    31741 tttacagtac gttgtctatt ttcgtcagtg gaaaagtaac tgatgtcgtt tatactaaac
    31801 aaaagaagat gcaggtaatg atcgtaacga aacatccaga aaaagtagta aatgaaatcc
    31861 aaaactgtat gcgtagaggg atcacgatca tcaatgaagc agaaggtgct tataagcatg
    31921 ataagcagac agtattgatg acgatcgtta cacgatacga actgcctcta cttagagaag
    31981 caatgaaagc ttctgatcca caagcttttg taagtattgc agaaaacgtc cagatacttg
    32041 gtcgtttcta tgaggatggc atttagatcg agtttgacaa aaattcatga aatactgctg
    32101 tagacagacg ttcgtttgtc tgcagttttt ttctaccata gtagaatcag caaagaaaaa
    32161 ctgctttttt atttgaaatt ttcttaaagt tgaaaaaaag catgtttatt tttttaaatt
    32221 tatgggatga tagaaaaaaa tagtagagaa aggacacgat tctacttgct attttcactt
    32281 aatacccgta tattacgaat gaaaaaagtt tatgaaaagt tggaatattg aatggaaaaa
    32341 caaaaaaggt taaaaaacag ccgctacatc actgggtttg atgggctccg ttcattagct
    32401 gtggtgggtg ttatcttcta tcaccttctg ccaactagta tgaaaggcgg ctatttgggc
    32461 gttccgattt ttttcgtcgt atctggttat ttgatcacgg atctgctgcg gcaggaatgg
    32521 gaacaaaatg gaaaaatcaa tatttggcaa ttttatgtca gaagaatgaa gagactctat
    32581 ccggcacttg tttttatgct tgtgacagct tcggcttata tcactttgtt tcagcgaggg
    32641 ctgttaaaca atcttcgagg agttgtggtc agcagcttac tgtatgtcaa caactggtgg
    32701 caaatcaata acggtttatc ttatttcgat cgatttgcta atgagtcacc gtttacgcat
    32761 atctggtctt tagcagtaga aggtcaaaac tatttggttt ggccgatctt gtttgtattg
    32821 ttgatggtat ttgttcgtaa aagaaaatgg atcttttata ctgtgttagg tacatccttc
    32881 ctctccgcca tcttgatgat gatcttgtat acaccaggag gcgatccaac ccgtgtttat
    32941 tacggtaccg acactcgtct gttttctata tggttgggaa gtgcgcttgc gtttgtttgg
    33001 ccaagtacgc gtttaaagaa aaacatcccg aaacaagcga aaaatattct gaatatcgct
    33061 ggaggaatct cgcttttggc actgattctt tgcttcttct ttttagatga tcattacaat
    33121 ttcatctatt acggaggaat gctcctagtg agtctgttat gcgtagtgct agttgcagtg
    33181 acagcacacc ccggagcaag tttgaatcga tggctgacaa atccagtatt tacttggatt
    33241 ggcaaacgaa gctatggcat ttatctgtat cagtttccag ttatgatttt ttatgaagca
    33301 aaggtgactg atattgccga tcatgttttg ttgcatactt tagtggaaat cacattgatt
    33361 ctaatcatca gtgaactttc ttatcgatat gtggagcgtc cgctagcacg ttttgattat
    33421 ggtcgtacat tccaagtgat gaaaggatgg ttcagcaaac cgatcatcag taagagcaaa
    33481 ccatgggttg ttccaggcac attacttgta gcaattgcac tcgttggttt cgttacggca
    33541 ccgaaaaacg ctgtaacagc cgatcaaaaa caactgcagg caaaaatcgc tgaaagtaaa
    33601 aaattagcag aagaaaccag aaacaattca gaaaacacca ctagttcggt tgaccaagcg
    33661 atccttgata agtacgagtt gtccaaggca caagggaata aggcacaaaa attagaacta
    33721 acggcatttg gtgattcagt tatgttggat gctgcaacgg atctacaaga actttatcca
    33781 aaagtagtgg tagatggaga tgtcggacga caattatatg ccagtgtacc gtacattgaa
    33841 aaattaaagg aacaagattt gttgaaagac actgttctga tcggactagg aacgaatggc
    33901 tcattctcgg aagctcagtt tgatagtgtg atggatgcaa tcggtgatcg aaaagtatac
    33961 tgggtcaatg tccgagtacc gacgaagcgc tggcaaaatg acgtgaatgc gatgcttgaa
    34021 cagatgacga aaaaatacga caatatgacg ctgattgatt ggtacagcta cagtaatgac
    34081 catagtgact ggttttatga tgatcaagtc catccaaatc ctgaagggat gacacattac
    34141 attcacttag tcagcgaagc cttgctagga ggaagttcaa gtacgaacag cagtgagaca
    34201 aacgtgacag aatgatagct acaaaaaact tcaggcaaaa acatttgttt ttgcctgaag
    34261 tttttttata tttaccgtgt ttttaacatt catatagatt caggaagcaa aacggttgag
    34321 tgtgtctgta aataacgttc tttttgtttt cgggtgagtt ttttgaatgc agcttctgct
    34381 tttgttgctt cgcttcttga agaaaatact tctgcatgga tcatcttaac aggtcttctt
    34441 ttttgaagac gagtatattt agcaccagta ccattgttat gttcctctaa tcgtctagaa
    34501 agatcggttg tatatccacc ataaaatgtc tgatctttac agaataatac gtaaaaataa
    34561 tgttcatttg ccatagagca tctcacgaat ctctgcagtg tattctccat ccatattgta
    34621 agtgatcaat ggtggagcga ctttgaatcc gtctaatttg ccttctttga ttccttcaac
    34681 taacaaaata tttgcctctt ttccaggttt tgggtaaaca aattggatcc ttttaggtgc
    34741 aattcgatag tcttccatga cctgaatgat ttctaagaac cgatcaggac gatggaccat
    34801 agtaaagcgt ccatttgttt ttagtagctt acttgaaata tcgatcactt cttctaacgt
    34861 cgtatgaatc tcatgacggg cgattgccag gtgtttatta gggttcgttt tatttgttgg
    34921 cagccctttg aaataaggtg gattacagac gactaagtca caagaattat gtcgaacgac
    34981 agataagctg tctttcagat cgatggtgtg gacagtcatt tgttcattta aatggttaag
    35041 cgcgatacta cgtcttgcca tgtctgctag acgaggttga agttcgatag cgtcgatagc
    35101 cgcctgggtt cgtttactta aaaaaagtcc aactgcgcca tttcctgcac aaaggtcaac
    35161 aatcttccct tttttaggta cacgggaaaa gtgagcaagc agcacagcat ctaaagaaaa
    35221 agaaaacact ttggaacttt ggataatctt gatatcttct gcgtataatt ggtcgattcg
    35281 ttcgtcttcg tgaagcatgg attccctcca aaatgaaaaa aatagtcgtc tgtattatac
    35341 tatttttatt aaaaagaacc aaggtggctt gtcaaacctc tattttttat gcatactatg
    35401 accataagaa gggaaaggaa gagactatgt tttatcgatt tatgcgcggg gtagttcgag
    35461 tactattagc cttagttaat ggaaatgccc gctatgagaa taaagaagtt ttaccgcaag
    35521 atgagaatta catactagtt gctccccatc gtacttggtg ggacccatta tatctggcgg
    35581 tagctgcagc acccaaggaa ttcagcttta tggcaaaaga agaactgttc aaaaatccag
    35641 ttctgcgatt tatattaact cgatccaatg cttttccagt taaaagagaa aatccaggac
    35701 caagcgtcat taaaacacct gtaaagattt tgaaatcgac aaatttgagt ttgatcatgt
    35761 ttcccagtgg gacaagacat gctacagaac ttaaaggcgg aatggcattg atttccagaa
    35821 tgtctaaagc gaaaatcgtg ccagctgtat atcaaggtcc gttgacactt ggggatctgt
    35881 tcaagcgtca gagagtgaca gtgcgtttcg gcgaaccaat cgacttatca gatatcaaga
    35941 aaacggataa agaaggtatg gcggagatcg aacgacgaac acaagcagct tttgacaaat
    36001 tggacaaaga agtgaaccct gatttcaaat atgaagtcaa aaaaaaataa aatgataagt
    36061 ttatgcgtgg gcggtctttt gaatctactg tcctgttcag ttcagacttt ttcaatgaaa
    36121 acgagggaga gacgtcaagt ctgccctctt tttgcgttcc aatatgtaaa atagaagaca
    36181 ggtgtcatgt aatggatcaa agtgttataa taattagaag gacatttttt gaggtgattg
    36241 aatgcgtttt ttacatacag ccgattggca tatcggaaaa aaactacaag gttatgactt
    36301 gattgaagac cagcgtcatg tactatcttc tatactagat atcgcgaaag aagaaaaagt
    36361 agaggcaatc gtgattgccg gagacttata tgataggagt gtcccagctg ttgatgccgt
    36421 agaattatac aatgaattga tggtcgattg gaatttaaag gaaaagatcc cgatttttgc
    36481 tatatcagga aatcacgata gcagtacgag actttcagcg ggtacgccat ggttcagtta
    36541 ttcgaactat tttttgcgaa cacagctagc agaagcattt gaaccagtcg agtttaaaaa
    36601 cgtacaattt ttctttcttc cttactttga accaattgca gcgagattat attttgaaga
    36661 tgacaatatc cgaacgatca agcaagcggt agccaaggtg atagataaaa tgcaggagct
    36721 atttgattca gaaaaaaaac aagtattgat tagccatttt tttgtaatgg gaagtgtaaa
    36781 atctgattcg gaaacgaaaa tcgaagtagg cgggttggat tcgatccctg gtgaactact
    36841 tacaccgttt gattatgtag cactaggaca tttgcataat caagctgctt tgagacagga
    36901 taatgctcgc tatagcggtt ccccattgaa attctcttta tctgagatca accaaaaaaa
    36961 aggcgtatgg atcgttgacc tgacaacagg cctggagttg aattttaggg agatcgaacc
    37021 cctgcatgat attgaagaaa taacagcgag tttcaaagaa ttgctggatc ctgcctttta
    37081 tcagtccgtc aatcgggaga attacatcta tatctatctc actgatagaa cgatcatccc
    37141 gaatatgatg aaccagcttc ggcaaatata tcctcgtatt ttggggattg aacgggcaaa
    37201 cggtcgagca gaacaaacaa agcgcaaacg aaaagtacta gaaatgaaag atcctcaaaa
    37261 attagcagaa gcatttttta gtgaaatgac ggaagagcag ctaactgcaa accaagaaaa
    37321 atggctcgga gaaacgttgc aagaaatcat ggaaatggaa tgatcaagaa tgaaaccgaa
    37381 aaaattacaa cttaaaaatt ttggtccttt tatcaatgag accgtagatt tttcacgttt
    37441 gacagaagca ccgctttttt tgatcagcgg gaagacagga gctggcaaaa cgacgatttt
    37501 tgatgggatc accttcgcac tttttggtga aacttccgga agacttcgct ctggaaaaga
    37561 gatgcgttct ttgtttgcta caccagacga agaaacaagc gtgacttttt cttttgaaca
    37621 tcagcagatg agctatgaaa tcgaacgaaa accagaacaa gttttagcaa aacgaaaagg
    37681 aaacggaaca aaaaaacagg cagccaaagt aacgttgacc atttttgatg ggaaaggaaa
    37741 agaaataaaa caaatcacaa aacgtacaga agcagatcag ttgatcagag aactgatgaa
    37801 tctcgatgcg aaacagtttt ctcaaatcgt tttactaccc caaggagaat tccgtaattt
    37861 tttggtttca tcaagcagtg ataaagagac tgttttacgt catttattcg gtactcaatt
    37921 tttccaacag ttcaatgagc gattaaaaga aaaagcaaaa caacagcaac aaaaattgga
    37981 tcatttagag caagagctgc atcttctgca aaaaaggttt gttttagtca aagaagagga
    38041 accagcagca gggtttgaag ccgttttagc ccaatggaca aaccatcagg caatactcga
    38101 aaaacaaatc acggaagaaa aagaagctct aacggaactt caggaaaaac aaaagcaact
    38161 agaaaattcc tactatcgtt ttgaaagctt gaaaaaaagt tatgaagaaa aaacgatatt
    38221 aataaacaag caaaaggaat tagctgctca aaaagacgaa atagaggaaa agaaacgatg
    38281 gattgggtat tatgaattta cgcaacgatt agtcgaacca atccagcgcc tacaagaaat
    38341 aaaagttgaa aaaatagaac tgtcacaaaa aagtagtgag caaacaaaga aactagcgat
    38401 gactacgcag aattatgaag agtggcaaaa aaatgaagca aaccgcgtac gccgacaaac
    38461 aaaaatcaaa gaagctgctc aaaaactgca aaacaaacag atgatggtgc caattgtcga
    38521 atccttacgt agtaaaaaac aagacgcaga acaattaaca atttcattgg ataaagaaga
    38581 attgaatgcc gagaagctgt atcaaaatct cgctatctat caggaaagaa ctcgaattct
    38641 tcaagaaaat ttactggatc aggaaaaact gcaagaagat cgtcttgctt ttggacagtt
    38701 aaaatatcta gatgaaaagc agcaagaaat agaaaaacaa aaagcaaaag acactgggtc
    38761 gctcgcacag ataagagaag aactcaaaaa agcaactgaa gaaataacaa aaaatagtca
    38821 gctattgaaa gaacagacag aacaagcaga acagctgaaa agccaatggg caaagcagca
    38881 aattgctcgt cttcagcttt ttttgcgtcc aggggagcca tgtcttgttt gtggatcaac
    38941 ggaacacccc atacaacaat taaaacacga acagccaaat aaggaagata tcttaaaagt
    39001 agaacaacaa ctggcagaag ctgagtctgc tgtagaaaga actcagcaaa tcattgccaa
    39061 aagtgaagca catgaaaata atcttcaaca acaattatca gatttagaac aaaaaatcat
    39121 ggcaacgaat atacaattgg ctgaacaaga agaacacttg caacaggctt tgaaaaaggc
    39181 atttcctgag ataacagaac aaaaaacaaa aacaactctt gtagtaatcg aacaatcttt
    39241 agatagacga aaaagcaaga tggccaatgc aagaatagag ctggaagaaa taagacaaca
    39301 agcagaaaag ctcgaacaac aattagctgt ctacaaacag cagcagacag aaaaaaataa
    39361 tcagctccag caactgcaag gagaaatcaa aagtttagaa caacaattgc aagatacgga
    39421 tagtaactgt ttagaagagg agatacgacg acttgaaaaa cagttagaag aagactcgaa
    39481 tcaactagct gttgagcaga aagcaggagt gcaattgttg caagatcttc atacgcttcg
    39541 gacacagctt gatcttcaac atgaacaaat agaaaaaata gatgaaaaaa tagaaaagga
    39601 acaagaaaga atagctaaaa agttagaaag ccagtcgtat ttttcaacaa ttgaagaaat
    39661 ctgtgcattt gcacaacagc aagcacaata taaagaaaac caacgtacag ttacttctta
    39721 tcatgaagag caattagtga cagctgaccg gctgcgtcaa ttagaaaata tccagctaac
    39781 tgagacattc ccagatacag aagagatcag ccaacagtta gaagaaataa gacgtatgat
    39841 cgaaataaag caagaaaaga tatacggttt acaagaacaa aaaattagta atcaaaaaat
    39901 ctacgatgaa tgtctttcga tttatcacac aagccagacg aaattagatg agcttacgca
    39961 attacagcag ctttcgcaaa cattcaacgg agaaaatcct aagaagacta gtttggaacg
    40021 gtatgtgctt caggtttatc ttcaagaagt gttacaagta gcaaatgatc atctccaacg
    40081 tttaacgaaa aatcgttatc aatttgagct agcggatacc attggcagtt atcgagggaa
    40141 aaccggatta gaaatcaata tctatgatga tcaggcaggt atgtctcgaa gtgcgcatac
    40201 cctgtctggc ggtgagagtt ttattgcagc actttcttta gcattagctc ttgccgatgt
    40261 gatccagaca caagctggtg gtgtagcaat cgatgcattg tttattgatg aaggatttgg
    40321 gtcattagat gaagaagctt tggaaatggc aatggaagct ttagaaacga tcgaaagtga
    40381 aggaagaatg atcggcatca ttagtcatgt aagagaattg aaagaacgag tattacaaca
    40441 aataagaatt gatacagaag gtagcggaca aagcaaaata cgctatcaac ttggataaaa
    40501 agggagattg gtaactatga aatggagtat tccagaaaaa gtcattgcac gtggacgtca
    40561 atacttgcaa gaaggccgag tgttatcggt tgtccctgac caagaagaaa acgtgtggca
    40621 tgcagaagtc ttgggcagtg aattgtatat ggttgatttg gatggtacag caaaagagat
    40681 agattactgc caatgtccct attgggagga acataaatat tgtaagcata cagttgctgt
    40741 ggaactttat ttacggtcga aaaatctatc tcgtatcatg aaaaaagacc agccaatgct
    40801 agaaccggta aaagcaacaa gtgagggaga aatcattgca aaaggttttt ctcgtctaaa
    40861 aacacaaaac aatcctcaag cggtgcaacc tttgattatt gaataccaag tagaaacgat
    40921 tgagactaat cagtatcacc cagagctttc tattttggca ctttacttgc gtatcggttc
    40981 attggcatca ccgaaaaaaa catatatcgt aaaaaacatc tatgattttt tacaagctta
    41041 cacagaaaaa gaaacttaca ctgttaataa acagtaccag tttcgtctag ataaacgggc
    41101 gtttcaaaaa gaagatcaaa aaatactcac gcatcttgca ggaagtgctc agacgcatca
    41161 attattaggt acgaacggct tacaagtcaa aggaaaacta gataaaagat atctgcttct
    41221 cccagtagaa caagcccgct tcctgttaga gcagatgaat cagactacac gtttgcatct
    41281 gcagataaat gaacaaaacg atcaaggaat acaattttcc gatcaaaaca aacctttatc
    41341 attcaaagtg gaaaaatttg gagaagatta tttgctgcaa gcattgaatg attttgattt
    41401 tttctttatg cattatcagt ggggagttat ccaagggaca ttttattctc tgacgaaata
    41461 tcaacaaacg gtttatcaaa cttggaaaca attgattcgc cgattggaga aaccagaagt
    41521 agtgttcaag aaaaaagaat taccgtcttt gtttaaagag attatccctc tgctgtcaga
    41581 gatcggcgac gtagctattg cccctgcagt agaagaggaa gtagcagata tccccgtcga
    41641 atttattttc tttttccgaa aagcaaaagg aaaaatccaa gctcgagtcg atttcgtcta
    41701 tggcgaagtc atctattcga ctgacccgaa gcatgaggtc tcgacagaac aggcttttca
    41761 ggtgttacgt gacacagtag aagagaaacg agtacttgat ctattcagaa tgtatcgcta
    41821 ccagaaaaat gaaactggtt atgaacgtcc attgccaagc ggggaagaac tatatgcctt
    41881 tttccgcaca gaactatctg tcttccgtca gtttggtgaa gtcagacttg gaagaaaatt
    41941 gcgagagttg tatttagatg cgcataaaca tcaaccgaaa atcgaagtaa ccgagaccgg
    42001 ttcatggctc gatattcgat tcgatgtgac agggatagag gagcaagaaa tcgatcatgt
    42061 cctgcaaagc ttgctgagaa atgatgcttt ttatacatta gaaaatggtc aggttctttc
    42121 ttttgattca gaagaatttc aacaaacaag ccaagtgttg caacaattac gggaatcgat
    42181 acgtacagaa gaaggaacga tccatgtacc taaaaatcaa ggattgatca ttcaaaatca
    42241 attggaaaaa agcaatgcta cttttagtga atcgttccaa acgatggtac aagatctcat
    42301 tcatccagaa agataccagg cacagcttcc caaaggattg aatgcaacga tgagagatta
    42361 tcaaaagcaa ggttttcgat ggttgaagat gttaggtcat tatcagtttg gcggtatttt
    42421 agccgatgaa atgggacttg ggaaaacact acagacaatt gcctttttac tttcggaaaa
    42481 agaagaacgg aaaagcttct ctgctttgat cgtagcgcct gcgagcttaa tttacaactg
    42541 gcaggcagag gtgagaaaat tcgccccttc tttaagtatc caagtaatca atgggaataa
    42601 aaaagaacgt gaagaattac tggctaaaga cacagatatc cgagtgactt cttatgccag
    42661 cttaagacag gatctagcta attatcagtc gcaaaaaatt gattatttga ttcttgatga
    42721 ggcacaaatg gtcaaaaata gcagtacgaa aactgcacaa gcattgagag aattagctgt
    42781 acctcagcgg tttgcactga gtgggacacc aatcgagaat aatttagaag aattgtggtc
    42841 attgtttgca acgattatgc caggattttt cccgactaaa acaaaattca gggaacttgc
    42901 cgcagaagaa attgcgcaaa tgattcgacc gtttatttta cggcgagata aacaaactgt
    42961 gttgaaagac ttgccggaaa aaacagagat gaatctatat tctgcactta cagaagaaca
    43021 aaaaactgtt tatttagctt acttgcgtca aatgcgtgaa gaaatcacat caatggattc
    43081 tgaagcattc aagaaaaacc ggatcgggat acttgctggt ctgacaagac tgcgacaaat
    43141 ttgctgcgat cctcgtctgt ttattgaaga ttaccaaggc ggttccggca agctcgaaca
    43201 agtaaaagat ctactggtag ctgccaaaga gaacaaacga agagttttgc tgttttctca
    43261 atttacaggg atgctgacta tcttgcaaga agagttagcc gagctaggga tctcgacatt
    43321 ttatttaaga ggcagtacga aaccacaaga tcggttaagt atggtagacg catttaatgc
    43381 tggcgaaaaa gatgtttttc tgatttcctt aaaggctggg ggaactggat tgaatctcac
    43441 gggagcagat acggtcatct tgtatgacct ttggtggaat cctgccattg aagaacaagc
    43501 tgctggacgt gcacatcgga tcggacaaaa aaatgtggta gaagtgtggc gtatgatctc
    43561 tgaaggaacg attgaggaac gcatggattc actccagcaa gaaaaacgcg aactgttcca
    43621 aaaagtgatc caaggtaatg aagaacagtt gacgaaactg actgaagaag acatccgcat
    43681 gattttaagt gtaggagaaa tcgaggagta agagactcga aaaagcgttc agtaatgggt
    43741 aagaaagcct ttctaaagaa gcgattgttt atttgattta aaaaatagca aggaggctgg
    43801 gattccattt tatcccagct tccttgctat cattttttta tttctatttt taaaggttat
    43861 acaaagattg tcttcattgt ctctaacagc tgatcaaaag aagaaatctc gatatcgcaa
    43921 attggagtct gttcaatttt gcgttctcga tggttgaacc aaagcgcttg ccagttagca
    43981 ctttttgcac ctagaacatc attgtcgtaa ttatcgccaa cgtataaggt ctcttctgga
    44041 agcatatgaa attctttctc agctagctga aaaatctctt tttctggttt ttggaaacct
    44101 gttgcttgag aaatgagcat attgcgggaa ggaatccaat tgttcaattg aagttgcttc
    44161 agtttttttg tctgatggtc agtcggccca tttgtgataa ttcctaatgg gacattcttt
    44221 tccttcaaga aatcgagggt ttttttgacc tcctcatgca agcagatatt atcaagttct
    44281 tcctcgtaaa ttttttgaaa taagaggcca tcttcttccg taatatgagg gtagtctaaa
    44341 tcttttagtg attggctgat ccgatgtgct cgcatatatt ctagtgtcca atctcctgcc
    44401 attacttttg ggaagttttc atcactatga tggcggaacc ggatatatag tggatgcata
    44461 tctgcatctg aaacaagcgg aacgactctt ttgaccgcgt ttcgaaatgg ctgctgctga
    44521 tcatacatcg tatcatcaac atcaaacaca actgatttaa tcaaaatttt acacgccttt
    44581 cggttttcat tgattttttc acaaatcctt gactattgta acagaaaaaa ttgtctaaaa
    44641 aagctgataa ataaaggttt ttcttactat atttctattt ccttgacaga ataaggtttt
    44701 tatatttcag tttttttcac taaaaatcgt gaaacacgtc aataagtttg atgaacaaat
    44761 taatcattat ggtagaagtc gattgattta ttttaatgca atctctgtgg aattttcgaa
    44821 agatttattt ttttaataca gtctcaatat aactattcaa acataaaata acgttatttg
    44881 atttatttgt ttatagtaaa ttttatttag taatcattgc tttaaaatac tacgcttata
    44941 taacagagaa aataagcgtt ataataaaga acagtattat ttaaaatgac agaaaacatt
    45001 actattaaag aaataaaaaa cataaaaaat cttaagaaat cggtttcatt tagcttttga
    45061 gataaaataa tagtacagtt ttatacgctg tttcatatgt ttagaaaatt tgaattagat
    45121 ttgaaaactc taatttttaa atgataaaaa aagcgagaat gctggtttta ctgtatatta
    45181 accttagata actttcattt ttttaaaaaa attatgaaaa aaaggtagct atttaaaagt
    45241 tgattatgta taatagaaac agatgggaga ttattatgat cttctgttac aaaaaagtga
    45301 ttcttatcac gaaaaggagt ggtgcacgtt gttaacatta tatacttccc caagttgtac
    45361 ttcctgcaga aaggctcgtg cgtggttgca agaacatcag attccatttg ttgaacgtaa
    45421 tattttttca gaaccattga acagttctga attaaaagcg attttacaaa tgacagaaga
    45481 cggaacagaa gaaatcatct cgacacgttc caaagtattc caaaaactga acatggattt
    45541 agatgatctg ccgttacaag aattattgga acttgtgcaa aacaatcctg gattgcttcg
    45601 ccgtccaatc atgattgatg ataaacgtct gcaagttggt tttaatgaag atgaaattcg
    45661 tcggttccta ccgcgcgatg tacgacaatt agaattacgt caagcacaat tgatggctgg
    45721 attatagaag gataatacga aacttggaaa agactattac aaagatagtt tttccaagtt
    45781 tttttgtttt tacaaaaagt attcttgatt agatgtataa aaaggtagta gaagatgatg
    45841 attgcacgaa aaatagagag ggaaaattag ctgaaaagtc ggctatatag tattcgtctg
    45901 ccaaaaatgt tatagttaaa taagatagct tgaaaggttg aaaaatccgc tggttttatt
    45961 aaattcgctt aacagcgaga ttttttttct ttacatttaa gctgatttcg ctacaatgaa
    46021 tctatattaa acattgtggc aaagtgaggt gtagcaaaat ggaaatggaa catattaatg
    46081 aaaatacgat ccgtgtacta attggtcatg aagatttaga ggaacggggc gtttcatttt
    46141 tggatttact tggcaatcac aaagaaatcg aaaatttctt ttatagtatt ttggaagaag
    46201 ttgatatcga agaggagttc cgaggaagcg aagctgtcac tttccaagtt ttgccaaaag
    46261 gagacggatt agaactgttt atcagtaaaa atcttccgga tgaagaaatt tctcaatcag
    46321 aagattctac tgttgattca gaagatgtga gtgactttct tcgtcagcag attattggca
    46381 gcgatccgga ggaagaatta tctggaagcg ccctagaaga acaggaaaga caagcaactt
    46441 ttgcttttga agattttgaa caagtgatcc aacttgcaac agatgtcgaa ctagagtctg
    46501 cttggactga tttgtattta ttcgaagagc gctattacct agtcgttcac ttctggatgg
    46561 aaaatctcaa ccaagcggat gtagagaatc agattgctcg aattttggag tttgctgaaa
    46621 agagcgatcg tacaccagaa acattgaatg aatatggaca atgtctgatg gcgcgtaatg
    46681 ctatcgagcg aacgaaattt tattttgtat aaatcagcat tatagtaaga gactgtgaca
    46741 aaaattgtgt cgcagtcttt ttttcgtata aatgtgttca aaagcttgca tctgcggtaa
    46801 caagcccaac caaacgaaaa atattgggaa ctatttttgt ttagctgttc ttattacttg
    46861 atgcagaata gctttttcac gccctctttt ttcgtgtaaa taaattctta gacgtaaata
    46921 agttcagagg gagaaaaatg ctgcttgcaa tgaatgaata taataagtgc tgttttgcta
    46981 aacatgcaga aaaaggaaag aaatattatt gtcgtggctg tcgaaaaaga gtgattttga
    47041 aaaagggaaa gaaaaaatgt gctcattttg cccatcaaaa atcagataac tgttcggtct
    47101 ttagtgaaag agaatcaaaa gagcacttac agttaaagga atgcttcatg gattggctgg
    47161 gacagtcagt agaaccagta tttttggaag cctatttgcc gaggttgcgg caaaggccgg
    47221 atattttgtt ggcgaatcta gcaatagaaa tccaatgttc tagactgtct caccagagat
    47281 ttattgaaag aacccaaaat tatttgaata acagttacca agtatggtgg atacttggta
    47341 attcttttct tggacaatcg caattctcat tgatagaaaa aagttgctgc tactataata
    47401 gaaaaagagg agtgcattgc tggaaagctg atctcaagaa acaaaagctt tatttgtatc
    47461 atcatattac agagactgta tcagggcata tttccttttg cagtagctgc tggacttttt
    47521 ctagtaggga ccttaaagaa atattcacta gtaacgaaat taaaatgaac caaatgaaaa
    47581 aaatagaaaa agtgagtgaa gatgggaaga aatggctgac acgccaactt attcacaagc
    47641 aaaagaatac agtatccata caagaacaat gctacttgcg tcataaacat cttttgcatc
    47701 tatcatcgtg gatctatcaa aaaagtcggt ttttctttta tttacaagaa caggtttttc
    47761 tttatcgaat gttgtacgaa gaagccttgg aaaaccagaa agttcctgat ttcaactcat
    47821 ggctttgcca aataaaagaa cataaaaggg aatggctttt tcctatgatt gatgaagaga
    47881 tggtctatca gcagtttttt aacgaatgca tacacttgtc ttctttgaaa aaatagtaag
    47941 tataaaaata ggctaggaat cggttttcta tgtaaaacaa gatttagtta tgctaaaatt
    48001 gatggaagca gacacatgaa tgagtagaaa agttagatgc tgtgacatgt ggatgttaga
    48061 ctatgatcta ttttgataga tagagctaag ggaagaaaag gagtggattt catggaagta
    48121 aagcagttgc caaaacgaga agaattgcct gaaaatttaa cttgggactt gaccaagatc
    48181 ttttcaagcg accaagagtt tgatgagaaa tatttggaat tatcagaaga gttaaaacaa
    48241 tctgaaaaac acaaaggaac acttgatcaa ggcgcttctc aatttttaaa tgcgattgaa
    48301 ttcgtattga gggtttatcg ccaaactgaa gtcatttatg tatatgcgca ccttaaaaac
    48361 gatcaagaca ctggaaatac agattaccaa gcgctttatg caagagcaag cagtctgttt
    48421 tcgaaagtta gtgaagccgt ttcctggttt gaaccagaaa tattgcaatt gtcagatgac
    48481 cagatttggc aatatttcaa agaagaacca aaattggaag tctatcgcca ttatatccag
    48541 caaatagtag ataatcgagc ccatgtctta tctgctgagc aggaatctct tcttgctgga
    48601 gcaggtgaaa tctttgatgc ttcaagtgat acatttgctg ttttgaataa tgcagatcta
    48661 gtttttccaa cgattgaagg agaaaatggt gaaatagtcc aattatctca tggcgtgtat
    48721 ggtcagttgc tagaaagcac ggatcgaagg gtgcgcgaag cagcatttaa ggggttgtac
    48781 agtgtttacg aacaatttag aaatacattt gcttctactt taggcacaca tataaaagga
    48841 cataatttta aagcgaaagt ccgtaattac agctctgcca gagaagcgtc tttgagcaat
    48901 aatcatattc ctgaaagtgt atacgatact ttggtagacg tggtaaacaa gcatttgcct
    48961 ttgttacatc gatacatgga attacggaaa cgtttattag aagtggaaaa actgcacatg
    49021 tatgatcttt atacaccggt cttaggggaa gctccaatta cctttacgta cgaagaagca
    49081 aaagaaaaag ctttagaagc actgaaacca atgggtgaag aatacatggc catcgtagaa
    49141 aaagcattct ctgaacgttg gatcgatgtt gtcgaaaata aagggaaacg aagcggtgct
    49201 tattcttcgg gaagctatga cacaaatcca tatattttat tgaattggca tgatacgctg
    49261 gatcagctat ttacgcttgt ccacgaaatg ggacatagtg ttcatagtta tttcactcgt
    49321 tcgaaccagc cttatgtgta cggcgactac tccatctttt tagcagaaat tgcttcgaca
    49381 acgaatgaaa atatcctaac ggagtattta ttggaaacag aaaaagaccc tcgtgtacgg
    49441 gcttatgtac tcaaccatta cttggatggg tttaaaggaa cagttttccg ccagacacaa
    49501 ttcgctgaat tcgagcattt catgcatacg gaagatgaaa aaggtgtgcc attgactagt
    49561 gaatacctaa gtgatagtta tggtaaattg aatgcaaaat attatggtcc agcagtcgaa
    49621 gaagacccag aaattaaatt cgaatggtca cggataccgc atttttatta taattactat
    49681 gttttccaat actcgactgg cttttctgct gcttcagcac tggcgaagaa aatactaaac
    49741 caggaaccag aggcactaga gaactacttg gcttacctaa aagcaggtaa cagcgattat
    49801 cctgtggaag taatgaaaaa agcaggagtt gatatgacac aggctgcata tattgaagat
    49861 gcaatgtcga tgtttgaaca acgtctaaat gaattagaag aattgatcga tcgtttataa
    49921 ggctttctat ttttgatttt ctcgaataga aacgaaaaaa atacgtcggc tctcttgtaa
    49981 gggagtcgac gtatttttt
//
LOCUS       DBBGSP010000017        48296 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000017 DBBGSP010000000
VERSION     DBBGSP010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 48296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.017"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="ACIZE9_001133"
     CDS             complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="ACIZE9_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HGC6093008.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="ACIZE9_001134"
     CDS             complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="ACIZE9_001134"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HGC6093009.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(2298..2960)
                     /locus_tag="ACIZE9_001135"
     CDS             complement(2298..2960)
                     /locus_tag="ACIZE9_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6093010.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            3144..4790
                     /locus_tag="ACIZE9_001136"
     CDS             3144..4790
                     /locus_tag="ACIZE9_001136"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HGC6093011.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            4781..5863
                     /gene="uxuA"
                     /locus_tag="ACIZE9_001137"
     CDS             4781..5863
                     /gene="uxuA"
                     /locus_tag="ACIZE9_001137"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HGC6093012.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(5971..7524)
                     /locus_tag="ACIZE9_001138"
                     /pseudo
     CDS             complement(5971..7524)
                     /locus_tag="ACIZE9_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            7672..8813
                     /locus_tag="ACIZE9_001139"
                     /pseudo
     CDS             7672..8813
                     /locus_tag="ACIZE9_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(8939..10018)
                     /locus_tag="ACIZE9_001140"
     CDS             complement(8939..10018)
                     /locus_tag="ACIZE9_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC6093013.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(10121..10561)
                     /locus_tag="ACIZE9_001141"
     CDS             complement(10121..10561)
                     /locus_tag="ACIZE9_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC6093014.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(10618..11028)
                     /locus_tag="ACIZE9_001142"
     CDS             complement(10618..11028)
                     /locus_tag="ACIZE9_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HGC6093015.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(11208..11642)
                     /locus_tag="ACIZE9_001143"
     CDS             complement(11208..11642)
                     /locus_tag="ACIZE9_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6093016.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(11742..12590)
                     /locus_tag="ACIZE9_001144"
     CDS             complement(11742..12590)
                     /locus_tag="ACIZE9_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC6093017.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            12979..14745
                     /locus_tag="ACIZE9_001145"
     CDS             12979..14745
                     /locus_tag="ACIZE9_001145"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HGC6093018.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            14847..16106
                     /locus_tag="ACIZE9_001146"
     CDS             14847..16106
                     /locus_tag="ACIZE9_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC6093019.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            16253..17554
                     /locus_tag="ACIZE9_001147"
     CDS             16253..17554
                     /locus_tag="ACIZE9_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6093020.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            17557..18408
                     /locus_tag="ACIZE9_001148"
     CDS             17557..18408
                     /locus_tag="ACIZE9_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGC6093021.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            18421..19236
                     /locus_tag="ACIZE9_001149"
     CDS             18421..19236
                     /locus_tag="ACIZE9_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HGC6093022.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            19387..20553
                     /locus_tag="ACIZE9_001150"
     CDS             19387..20553
                     /locus_tag="ACIZE9_001150"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6093023.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            20783..21430
                     /locus_tag="ACIZE9_001151"
     CDS             20783..21430
                     /locus_tag="ACIZE9_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HGC6093024.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            21514..22458
                     /locus_tag="ACIZE9_001152"
     CDS             21514..22458
                     /locus_tag="ACIZE9_001152"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGC6093025.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            22593..24044
                     /locus_tag="ACIZE9_001153"
     CDS             22593..24044
                     /locus_tag="ACIZE9_001153"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HGC6093026.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            24065..24901
                     /locus_tag="ACIZE9_001154"
     CDS             24065..24901
                     /locus_tag="ACIZE9_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGC6093027.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            24901..25560
                     /locus_tag="ACIZE9_001155"
     CDS             24901..25560
                     /locus_tag="ACIZE9_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGC6093028.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            25686..26375
                     /locus_tag="ACIZE9_001156"
     CDS             25686..26375
                     /locus_tag="ACIZE9_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093029.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            26381..27337
                     /locus_tag="ACIZE9_001157"
     CDS             26381..27337
                     /locus_tag="ACIZE9_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HGC6093030.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            27381..27893
                     /locus_tag="ACIZE9_001158"
     CDS             27381..27893
                     /locus_tag="ACIZE9_001158"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6093031.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(28149..28697)
                     /locus_tag="ACIZE9_001159"
     CDS             complement(28149..28697)
                     /locus_tag="ACIZE9_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGC6093032.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(28786..29967)
                     /locus_tag="ACIZE9_001160"
     CDS             complement(28786..29967)
                     /locus_tag="ACIZE9_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HGC6093033.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(30203..31711)
                     /locus_tag="ACIZE9_001161"
     CDS             complement(30203..31711)
                     /locus_tag="ACIZE9_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGC6093034.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            31870..32061
                     /locus_tag="ACIZE9_001162"
     CDS             31870..32061
                     /locus_tag="ACIZE9_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093035.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            32264..33181
                     /locus_tag="ACIZE9_001163"
     CDS             32264..33181
                     /locus_tag="ACIZE9_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HGC6093036.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            33174..34247
                     /locus_tag="ACIZE9_001164"
     CDS             33174..34247
                     /locus_tag="ACIZE9_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093037.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            34395..34913
                     /locus_tag="ACIZE9_001165"
     CDS             34395..34913
                     /locus_tag="ACIZE9_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093038.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            34894..35286
                     /locus_tag="ACIZE9_001166"
     CDS             34894..35286
                     /locus_tag="ACIZE9_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HGC6093039.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            35362..36297
                     /locus_tag="ACIZE9_001167"
     CDS             35362..36297
                     /locus_tag="ACIZE9_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HGC6093040.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            36430..37209
                     /locus_tag="ACIZE9_001168"
     CDS             36430..37209
                     /locus_tag="ACIZE9_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGC6093041.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            37202..37519
                     /locus_tag="ACIZE9_001169"
     CDS             37202..37519
                     /locus_tag="ACIZE9_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGC6093042.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            37763..39373
                     /locus_tag="ACIZE9_001170"
     CDS             37763..39373
                     /locus_tag="ACIZE9_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGC6093043.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            39530..40378
                     /locus_tag="ACIZE9_001171"
     CDS             39530..40378
                     /locus_tag="ACIZE9_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGC6093044.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            40609..41088
                     /locus_tag="ACIZE9_001172"
     CDS             40609..41088
                     /locus_tag="ACIZE9_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HGC6093045.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            41121..43349
                     /locus_tag="ACIZE9_001173"
     CDS             41121..43349
                     /locus_tag="ACIZE9_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6093046.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            43478..45121
                     /locus_tag="ACIZE9_001174"
     CDS             43478..45121
                     /locus_tag="ACIZE9_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGC6093047.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(45194..45739)
                     /locus_tag="ACIZE9_001175"
     CDS             complement(45194..45739)
                     /locus_tag="ACIZE9_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGC6093048.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(45762..46247)
                     /locus_tag="ACIZE9_001176"
     CDS             complement(45762..46247)
                     /locus_tag="ACIZE9_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGC6093049.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(46237..47049)
                     /locus_tag="ACIZE9_001177"
     CDS             complement(46237..47049)
                     /locus_tag="ACIZE9_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HGC6093050.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(47188..>48296)
                     /locus_tag="ACIZE9_001178"
     CDS             complement(47188..>48296)
                     /locus_tag="ACIZE9_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HGC6093051.1"
                     /translation="ILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAHS
                     MGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKVV
                     HMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTSM
                     AQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLPE
                     NTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLIE
                     TINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELPR
                     LNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        15895 a         8764 c         9360 g        14277 t
ORIGIN      
        1 tcttgtcacc atcctttttt ccgctctctg actttttaca atcttcatag ctcaagtgcg
       61 catcagataa tcgaatgctc ctaaagctgc agtagctcct gaacccattg aaacaatgat
      121 ttgtttgtat ggactatctg tacaatcacc agctgcgaaa acgccgggga tattcgttgc
      181 gccatttttc tcggtcacta tttcatttct tggattcatt tcgatcgttc catctagcca
      241 atccgtatta gggagtaagc cgactagaat gaatactcct gaaacagcta gtgtatgcat
      301 ctccatcgta cggcgatcga tataggagag agattctacc tgattcgtac cgctgatttc
      361 tttcgtcgct gcatgtttga taacagtgac attcgcaaga gagactagtt tatcctgtaa
      421 gatttgatct gcttttaatt ctggtaagaa ttctagaaca tatacatgtt ttgctaaccc
      481 agccaaatcg attgctgctt caacaccaga attaccacca ccgataacag caatctcttt
      541 tcctttaaat aaagggccgt cacagtgtgg gcaataagca attcctttat ttttaaactc
      601 tttttcgcct ggtacattga tagaacgcca gtgcgcacct gtcgcgatga tggcggtttt
      661 tgctttaagt gatataccgt tagctaagcc aatattaata aaatgttgct ctttatttaa
      721 ggaaacggcc tgttgattca tcataatgtc gatagggtaa ctacgcacat gactttctac
      781 ttgctgcatc aattttggac cttctgtgta agaggtacca atcatatttt caatccctag
      841 tgtttcaacg acttgtccgc cgaaagaatc agcgacaagt cctgtacgga ttcctttacg
      901 tgctgcatag atagctgcac tactagctgc tggtccaccg ccaatcacta atacatcata
      961 aggttctttt tcaaacaact cttcttcaat caaagggcca gtgatttttt caacaatttg
     1021 ttcgatcgtc atgcgtccgc tactaaattc ttctccattt aaaaacacag ttggcactgc
     1081 catgattttt ttatcatcga tttctttttg gaacatccca ccttcaatca tcgtatgagt
     1141 aatatttgga tttaatacag ctaatatatt caatgcctgt acaacgtcgg ggcaattatg
     1201 acaagtcaag ctaacataac tgtcaaaatg caatgtttgt gttatttttt tgattttaag
     1261 actcaaagat tcactgattt tcggtgcccg tccactaatt tgtaacatag ccagtaaaaa
     1321 agaggaaaat tcatgaccga gggggatacc agcaaaaacg attccacttt ctttgccaac
     1381 tggattgata gaaaaactag gtgtgcgcat cgaatctctt ttttcccaag agattttagg
     1441 agacatttct gctatttcct tcgtaaattc agctagtttt tgactatttt cactattatc
     1501 caaactaaca gaaaaaacaa taggagattc aatcagtgct aaatattgtt cgagattttg
     1561 tttagtttct ttgtctaaca tatccaccac ctaaatcttt ccaacaagat caaaacttgg
     1621 tttcaatgtt tcgccacttt ctttccattt tgccggacaa acttcacctg ggtgggtacg
     1681 tacatattga gcagcgcgaa tcttatcaat cagtgcacta gcgtcacgac cgattccatc
     1741 tgcattgatt tccatagctt gaacgattcc gtctggatca ataataaatg ttcctcgctg
     1801 agctaatcct tgctcttcat ccaaaacatc aaaaatacga gaaatctgat gagacggatc
     1861 accgatcatc acgtattcga ttttaccgat agcatctgat gtatcatgcc atgctttgtg
     1921 agtaaagtgg gtatcggtag agcaagaaaa gacttcaaca cctaaagatt tcaatgtact
     1981 gtattgttct tgtaagtctt ctaattcagt aggacaaaca aaagtaaaat cagctggata
     2041 gaagcaaaga atactccagt tccccataag atctttttca ctgacttcta aaaattctcc
     2101 ttgatgataa gcatgtgcat taaattcttc gatttttttc ccaatcaatg acatagtaaa
     2161 acctccaata ataattattt atttataatt attgtaattt agttggagtt gcaaagtcaa
     2221 tggatatttt gttatttaat aaagattact caaaaacgaa ggttaattat aaaaatagaa
     2281 gaggtcgcaa gaaaatgcta ctgctggaaa tactcgggat aacgttgagt aacagtttcc
     2341 tgttctttca gcatcatgtg taagtgcaat cccgtttgaa atcgagcttc ttctggtttt
     2401 ttatcaacta aagccttgag taaatcataa tgttgttcca tgatcgtttc ccatggaagc
     2461 ccctgaatgg tcactcgtaa ccagcggaaa cgttctaaat gggtattatg gtcatctaac
     2521 cagttccaaa cttcttttct tcctgcaatt tcgaaacaag cttcatgaaa taaattatct
     2581 gcacggaaaa aagcgcgttc gtcatttatt ttgactgctt tttcttgttc ttctaaaatc
     2641 gtttctagca ctattcgtgt ttgtgtgtcc aatttggaac aacattcaat catgatttgc
     2701 tcttccaact gttctcggac aaagcgagca ttttctgcag aaacaagatt aattttggaa
     2761 acatacgtac cactttgagg tatcgtatac acgagttctt gctgacgtag ttgaatcaat
     2821 gcttcgcgaa tgggagtccg gccgatagca agatgttcct ccagtgcctt ttcagatatt
     2881 ttccttccag gttctaagtc agcatagata atttgtttac gaatcgcttg ataagcttgt
     2941 gattgcaagc tgcttttcat ctttattcct ccaaaatcat ttctatgaac gtagtataac
     3001 agaagaggtc tgaaaaacaa tctggtatgt cacattaact agtaaatttg tataaatagt
     3061 aaaattttgg ttgacatagc gatttttatt gcataaaatt cacttgaata caaaaactaa
     3121 tatgttagtt taggagggga aaaatgattg atttaaacaa ctggaggaac tttatccctg
     3181 aattatctca aaaagaagta gaaatacctc attttgaccg tgcatcatta agagaaaatg
     3241 gacaaaaaaa tcctgtctgg atccatttcg gtggcggaaa tctttatcga ggatttcatg
     3301 cagaaatcgc tcaacgttta gcggatctag gcgaattgtc cactggtgtc attgtttgtg
     3361 aaacattcga tgaagaaata attgaaaggg cttaccaaga ttttgatgat ttgattcttg
     3421 aagtggtcat gccaagcagt ggagagttcg tcaaacgtat attagctgcg acagctgaca
     3481 gtctgtattg tcatccagat tgttctgaac actttgataa gatgattcga cactttgaaa
     3541 atcctagttt acaattagtt acttttgcta ttactgaaaa aggttatcga ttgaaagata
     3601 caaataataa atatatagga ccgattgcag tcgatataaa aaatggtcca aagaagccat
     3661 cacatacaat gagtattctt gctgtgctac tttataaacg ttttttatct ggagcttggc
     3721 cgattgcact tgtctctaca gataattttt cacaaaacgg tagtcaatta cgtacttctt
     3781 tgctaacgat cgcaaaagaa tggcaaaagg aaggttatgt acaaaataca tttatccaat
     3841 acttatcgaa tgaagaaatt gttgcgtttc catggacgat gattgatcgt atcaccccga
     3901 atccttcctt gtcagttagc aaaatgttgg caaaagaggg cttttcaaat atgtcgattt
     3961 tccaaaccgc aaaaggaaat aatattgctc catttgtcaa tacagaggac atccattatt
     4021 taatcatgga agatcatttt cccaatggac gtccgaaatt cgaaaaagct ggggtattct
     4081 tgactgatcg tgcaacggta gataaagcag atacgatgaa ggtgacgact tgccttaatc
     4141 ctttgcatac gtctttagct attatgggtt gtttactggg gtataggagc atagctgagg
     4201 agatgaaaga tccagattta tcgctgctag tttctgaaat cgggtacaat gaaggcctcc
     4261 cagttgtgga gtctccaggt atcattgatc caaagatctt tctggaagaa gtaattactg
     4321 tgcgcttttc taatccaaat attcctaata tgcctcagcg aatcgccacg gatacctctc
     4381 aaaaggtggc gattcgttat ggtgagacga ttaaaaaata tatggaaata gaagttaaag
     4441 acccgcagac acttgtattc ataccattga ctctcgctgc ttggcttcga taccttattg
     4501 gcattgatga tcaaggaaaa ccattcatcc cgagtccaga cccactattg acagaccttc
     4561 agcataagct ttccgatatt caactgggta cgcaagatac atcacatatt catgagaaaa
     4621 tggctcctat tttgtcaaat aaagaaattt ttggtgtaga tctttaccaa gcagagcttg
     4681 gcagaaaaat agaagaaatg ttcatcaaga tggtagcagg accaaatgcc gtacgaaaaa
     4741 cattacagga ttacttacaa gaacatggag gaaatttatc atggaaatga cttttagatg
     4801 gtacggatca caggaagaaa agattacctt agatgaaatc agacagattc ctgcggtcaa
     4861 agggattgta ggcacattga tggatatacc agtaggagag gtatggccta gggagaggat
     4921 caaagaacta aaagaagaaa ttgagtctcg tgggttaaca ctaaaagtaa ttgaaagcgt
     4981 caatgtgcat gatgccatta aaattggatt accttcccgt gagcagtata tcgaaaacta
     5041 taagcagaca atccgaaact tggcagaata tggaatagaa gtcatctgct ataattttat
     5101 gcctgtattt gactgggtga aatctgacct tgactaccgc ttagaagacg gctcatccac
     5161 gttagctttt atatctgatg atattccaga tgatccaaga gaaatcgtcg cgcgcatcga
     5221 acattccagc aatgaatttg gattgccggg atgggaacct gagcgcttag ctcctatcaa
     5281 atccttgctt gaagcctatg catcagtaga cgaagaaaaa cttcgagaaa attttgccta
     5341 ttttctccaa tcaatcatcc caacatgtga agaggtaggg gtcaaaatgg ctgtacatcc
     5401 agatgatccg ccatactcga tttttggatt agctcgaatc gtaaagaatc gagaagattt
     5461 agattggttg tgtcgcatag tagacagccc ttataacgga atcactcttt gtacagggag
     5521 tattgcagaa gatccagaaa atgatgtata tgggatttta gcagaatttt gccaaagaga
     5581 tcgaatccca tttgcacatg ttcgaaatat taaattttta gctaatcgag atttctatga
     5641 ggcaccacat aaatccgaat acggttcatt agacatgtac cgcatactaa aaacaatgta
     5701 tgacaacgga tttaacggat acatccgtcc tgatcatgga agaatgatct ggaatgagac
     5761 aggaagacca ggatacggct tatatgatcg agcattaggt gctgtttatc taaatggatt
     5821 atgggaagca atcgaaaaag gaaacaaaag taaagataat tagtgaaaaa aactgtaatt
     5881 ttattatgta aataagaagg atgttcaaat tcttgataca taaatccgga ggttgttaat
     5941 aagcattcgg atttatgtat cttatttggt ctaggaagta acttgatttt cttttttcga
     6001 ttgatccatg agtgcttctt cttttaattc aaagatatat tctgagatcc tcataatcac
     6061 ttttttccag tcttctggtg tgatgattcc ttttaaaata tagatttttt tgatatgaga
     6121 aggcaattgt ttcaaagggc agtcgctgat aacgatgttg cagttctcca taaaatcatt
     6181 ttgtattttg atcgattcat ttgaaaaaat ttgttctatc ttaacgatca gatctttact
     6241 gatataaaaa tcacgcgtat agttcacacc aatcacaatt cgcggctgtt ttttgtagcg
     6301 atcatacaaa tgtactaggt cttcaaccat ccattgcaca ttttcctttt ctaaaataac
     6361 tggtaacaag tgttgatttt gttctctgaa atccatataa aattgttcaa tggcggtttg
     6421 gacttctttc aatacgctat gttcttgata aagcatgaaa gtaggaaggg gcgtatttgg
     6481 ttgattgaag ttaagaaatc cattataaag tttatttcgt gcgaatgcca atgagtaaag
     6541 aatcttttct ttttcaggta taaacaaatc aaatacagta caaagggact ccaccatttc
     6601 tcttgaataa agaacatgag gaacgtttgc tttttttaaa agtttgtatt gctccaagct
     6661 tgtttcttcc gattcgattt tcgtgataga aagtcgagct aaaatattca ctaagatgcg
     6721 ttgttcgcga caaattggca gattaggtcg caaaatatct acagagagat caataaaaaa
     6781 gtcaatatat tcatactctg tgaattcttt ttgtacgtct ttcacagaag ttgcaggaaa
     6841 attctcttta catattttta atagaaaata taatttatct atcataccgc tatttagtcg
     6901 gtcaagtact tcttttttaa aaaaagtatt catcataaaa gccactactt gcggatcttc
     6961 atcataaaat tctgtagcag tacttgaaaa gatgttccaa taaatatcta atgctgcata
     7021 ttgaatttgt acctcttttc cagaaaaaga ctttctgcca ttattagaaa aggagataga
     7081 caaaccgtac tatgctaaaa atgcattaat ctttttcatt ttcgtataca aataagaggc
     7141 actatagttt gtttgctgac tgaaactgat aatcgaattt gtctgacagc tgaacaaaga
     7201 agtcaagatc tgataactga ctgattcgtt gcagtatctt ccaaatagac gataatagca
     7261 gtaagccgga tcaattcctt caaaattcaa ctttaaaaaa ggtttttgct tatcaatatg
     7321 cagttctgtt agattgagac gctcaaagtc ttgttctaat tctttgatgt atagtaaaaa
     7381 atttgattca gacatatgga aatgatctgc taaatattgt gtagtaataa agaaacgatg
     7441 ttcagatagg aaaagaaaaa tatctaattt tgtattgctt tttttcttca agataaacgt
     7501 tttaatcgct tcttgagttt gcatgaaaga ggctcctttt tacttaaatt gttaaaactt
     7561 gaaaatatta ctgttttttt cataaattta gacaaaaaaa cagtaaacat ataggtagaa
     7621 tctctactat cttatttctt gcatacaaaa aaatcaagga gtgagagagt tatgagatat
     7681 tcaaccatct taatatcaac atttgcagcc ttaagcttat cgcttactat aaatcagaca
     7741 gtccacacag aggagacaga aacagccaaa tggacagaaa ccaagtgggc caacgtcaat
     7801 cgaattacct ttcaggatga attttcatcc ttcaattcag gagtcgcaaa attaagaaaa
     7861 ggacaaacag cgaccatcaa agcaaaaatt gactattcgg gagacttagc acctatacta
     7921 caatcagctg ttacatttga gaatgttgat cccactttgt cgattggcta tgacgagaac
     7981 actttgacta tccaacacaa gcaagcgata tttaccttca ccgttacatt aaatcaggac
     8041 ttgttaaaac cagcgctttt tactgtcaag gtatcagatg gactaccgaa cgatcatcat
     8101 ttaacgccgt atagtcagcg gcagacaatt gagcaagatt cagccatcga ctcaggagga
     8161 gatcttgttg aagaaccaac agataaacca gaaaatgaaa ataagccaga agtaccgcct
     8221 acagaaaatc cagacggaga acagaaaccg gaaatagaac ctggagaaga acccgataca
     8281 gaaactcaac cagagccaga caataaatca aaacctgaaa taacccctgg agaaaaacca
     8341 gatgtaactc cagaaccaga tacggattct ggaaaccaaa cagtaccgga aacaaatcca
     8401 gacacagata atgaaactga aaatccagaa aaaccagagg tagatccaga agaaaaacca
     8461 gatgtgactc cagaaccaga tacggacgca agagaccaag gaataccaga aaaaataaac
     8521 aaaaaaacaa ttcaagagga tggaaaaaaa gagagtaaaa aatcaaatct agcaattcta
     8581 aaaataaatg aagagcagct gaataaaaaa tcacgaatat ttgatagcgc ccaatcagct
     8641 gaaaccttaa aaagtagcaa ggatacaacc tttgctgtcc tgaaacgaaa aataaacagc
     8701 taccaaaatc cggagagtca caaaacaaag ttatactgtg gagcggaatc attctattaa
     8761 gtatagcaac aatgctttct gcaaaaagat ttaaacaaaa cagatctctc taacatttga
     8821 ataatgtctg tgaacgcatt tttcaaataa aaagaaatat ccagaaaatg accccaaaat
     8881 accagattga aatctgatat ttggggtcgt tcatacttta tctttcttca tatttatttt
     8941 aagggatatc tgtttctttt ggaagatggt tcgggatctt tttcactttc aatacatcta
     9001 aaaagaaggt aaagatcgga atgccgacaa tcaagcccca aacgccaaag aaccgttcgc
     9061 taacaagtaa gaccacaaat gtataaaaaa tcggcagttc tgttttgctg gacatcaact
     9121 tcggattcag cacataagac tcaattagat ggacaatcaa aatcgtaatc aggatataaa
     9181 caacatctcg gatgcctcct tgggaataag ctatgaaaga tagaggaata caagaaatga
     9241 taacacctgc tactgggatc agacttaaaa tgaaaatcat gatcgctaaa ctcagcagct
     9301 gatgaaagcc aaatacagcc aaggcgattg tagtgagcaa cgtatttaaa agagcgacaa
     9361 caaattgagc ttctaatacc aaaccaaatg tattgacaaa cttatcggca aaatagtaaa
     9421 tatcttgaaa gaaccaagaa aattcacttt ttaaaaacaa tcttgagaat acaattgttt
     9481 ttttcttttc aatcataaaa aagaaactta agatgaatga catagcaaac gccactgcca
     9541 tttttcctat atcctgtaaa tagccaagcg caatcgaagc gccattttga agctgttcaa
     9601 aaaaatcgtt tcgctcaata taagtatgga tatattgtaa aacaggatct gcatcttttg
     9661 gctgatgctc gtaaaaatta ataacggact ggatcatgtc aaatgtttga tgaataagca
     9721 tcgggatata ctttgtgaat gccagataga taaggtaaac gatcagtgta taaatcatga
     9781 tagctaaaac acctgtaggg attcggacaa atcgctgaat gatttgaaca agatgaatca
     9841 tcaaataagt aaagataaat gtgagcaaaa tggttgtaat catacttcta actaagaaaa
     9901 gaacaaaaac gacaaataat aaaacagtga gacggcgtat tttttcattc gccaaaaaac
     9961 gctgataaac ggtcaaatcg acaacctcca aataacaaaa aataaacacg ttattcatta
    10021 tatgatggaa tatgaaaata agaaagagca aaaagaaaaa ccgctaaatg acgttatctt
    10081 atgagttggt tttcctcata aaatcgttca tctagcagtt tcagcccttt ttctggtctt
    10141 gatgaaaatt atctagcatt tttcgggtca gatgttgcag tgtatccaat tcttcctgtt
    10201 caagtggaag ataagacttg atcttttgtg gaataccttc tgcttgtttt tgcaacgcag
    10261 caccttgagc agtcagcgta acatttacga ttctttcatc acccgtttca cgctgacgat
    10321 taatataatt tttttctgct aactttttta gtaagggagt cagcgtacca gaatccagac
    10381 acaaatcatt tcctagctct ttcactgaag tctttttctt ttcccataaa actaacatca
    10441 caagatactg ggtataggta agattcagcg gcttgaggag gggagtgtag tgtctaatga
    10501 tttctttaga ggcggcatat aaaggaaaac atacttgatt aactaaatat agatcttcca
    10561 tttttccacc tccgctgttt tactatagtg tatcatagcg gatttacaca aaaaagtcta
    10621 ttcactaact gctttcagag taacttctat atttccagct gtagcttttg aatacggaca
    10681 cactttatgc gctgcctcta ataattcttg cgtttcttcc agagaaagac cttcgataga
    10741 tccttcaatc tctacaccta agacaaagct cgtttcactt tctgaataaa gggaaacttg
    10801 tgcactgaca gtagaagccc cagagatatt tttttgctgt ttgatcaatt ctaatgcact
    10861 gttaaaacat gcactgaaac cagctgcaaa caattgttca gggttggttg cattttcgac
    10921 gcgtttacca ggagctgcaa tattcaattc gaatgtacga tcgggattat gcacttctcc
    10981 agagcgtccg cctgtgttga tcattttcgt agaatacatt tttttcataa agttaccacc
    11041 tttaattata ttttatacaa ttgaatttta cacaatataa ttgtggaaag caaagaaatg
    11101 gattggcata agataaataa gagaaagcac atgaaacaga cgcgctttct cgaatagcaa
    11161 acatatacaa aaaatatcag agacaaaaaa taatctcatc ataaacatta catatatttc
    11221 tcaaaaagtt gttttctttc ttcaaaaatt acttcacgat ggacctgatg aagcatccat
    11281 aaataaccaa aaggatctct gaacattgag ttagtcacac caaagtccat catttctgtc
    11341 atttcttgaa tctctacaca gccatttcgt aatgctttat tatgtgtgtc ctcgatatca
    11401 gagacgatga tattgaacca gatcgtattt ggatgttcag cagtaggagc agtcaaacca
    11461 agagacgtgt tttcatccag catatggaat ctcgtaccat acaaggtaaa aatgacttca
    11521 ttattgcctc tagggtaatc tgttgcctca atcagttgta tttcatcaaa gattgtttga
    11581 tacagttcta gtgctttcaa actatcattt aatacaaaat cgatttccgt tcctttatgc
    11641 ataaagatct cctctccttt tcagtcgaac agttactaga ttcttttatt ataccagcta
    11701 aagaaaacgc attcaaaaaa atagcggatt tacttaccaa ctcattcgat tggatgataa
    11761 gtaaatccgc gtcccattac ttctgctacg ctgctgacaa tgacaaaggc acttggatcg
    11821 atttcttcta tcaatggttt cattcgggaa aattcatgat cagtcacaac gatcaataaa
    11881 acctcttttg actttcgatt atacccgcct tttgcctcta gcagggtaag gccacgtcca
    11941 atctcagcac ttaagcgaag gcggatgtct tccaaataat gttcactcat gaccataaca
    12001 gatttctttc gattgatacc tgtttcgata taagtcatga caattgaagt gattgcaata
    12061 gataaaatag cataaagaaa ctcttctatt ccaaaaataa acagattaag agaaacaacg
    12121 aatgcgtctg taaaaaataa gccaatcgaa gtattcaagt ggaaatattt tttaaaaatg
    12181 aggggaggga tcgtcgtacc gccgctagaa gagttgtttt tatataaaat cgcaactcct
    12241 aaagcaaaaa tcgcacttcc aaaaatgaca gacaacaacc gatctgaagt aatcattgtt
    12301 tctggaacta ttgcaatgat taaaggaaaa accaagcttc cgaaaagtac tttaaaaaag
    12361 ggttttttac ctaaaaatag aagagctagt accaacataa cgatattcaa cactaaaata
    12421 actatagctc ggtcaaagcc taaagcagct tccagtaata ttcctagacc gctgacacct
    12481 ccagcagcaa tatgatgagg ccctaaaaac atattgatag cgactcctaa tatgaagagg
    12541 gcaaaaataa tcttaatgta tgtccatata aattgtctcg tttctttcat ttattcactt
    12601 ccttaattca ttaataatac tcttatctta ttataactta cttttcacct taagttaact
    12661 ttaattaata aaaaaattag gctagtctaa attattatgt ttcattcttc tagaatatac
    12721 ttctacgcca aaaactgtta aaaaactttt actttagaaa attggagaaa ttgatcgctt
    12781 aagataaatt caggacacta aatagtacag gaagtagact aaaactttta aaagttttaa
    12841 gtctatctat ttggcaagtt taaaaaataa aaattcggta tcaaaaaact gttaccgata
    12901 acatttttga aagcgttgtc ttttgcttct ctatcactta tagtgatgac gtcatattaa
    12961 aacacaagga ggaaatcaat ggatacagct gcaatttatc atcgaccgga aagtgaatat
    13021 gcatttctat atacgaatac aagatttcgt attcggcttc gtactaggaa aaatgatatc
    13081 aaaaaagtat atgtgctatg tggagatcca tataccataa caactgaaaa atggtatcaa
    13141 aaacaacgac caatgaaaaa atgtctaagt accaatgttc atgattattg ggaaattgaa
    13201 gtgacgagcg aaacaagtcg cttacagtat gcgttccatg ttgttgggga agataacacg
    13261 gactgttttt acggtgatca aggaattttt ccttatcgag aaaatgtgat tactgaacca
    13321 aatttttatt ttcgaatacc ttattttcat caaatcgatc gattcactat tccagaatgg
    13381 gtaaaagaaa cagtatggta tcaaattttt cccgaaagat ttgcaaacgg ggacaaagca
    13441 aatgaccccg aacacacttt accttgggga agtaaagatc cagaccgaga agactttttc
    13501 gggggagatt tgcaaggtgt gatggatcat ttggattact tgacggacct tggcatcaat
    13561 ggcatctatt tttgtcccat atttaaagcc acatccaatc ataaatacga tacgattgat
    13621 tattatgagg tggatcccgc ttttggcgat aaaaaacttt taaaaaactt gattgatgaa
    13681 gcacataaaa gagggatacg tatcatgttc gatgctgtat tcaatcatat gggtgtccat
    13741 tcaccacagt ggcaagacgt tctcaaaaac ggagaaaaat cgatctataa agactggttc
    13801 cacatccgtt ttttcccagt agattcttat cagatgactg acttaccaga aactgctgaa
    13861 aatatcccat atgatacttt tgcttttact ccattcatgc cgaaactaaa tacagcaaat
    13921 ccagaagtgc aaaaatattt gctggatatc gcaacttatt ggataaaaga attcgatatt
    13981 gatggatggc gtcttgatgt tgctaatgaa gtcgatcatc atttttggaa aaaattcaga
    14041 gaagcagtta cagaaatcaa accagacatc tatatccttg gagagatttg gcattcctct
    14101 caagcttggc tgcaagggga tgaattccat gcagtgatga attatgcatt tacagattcg
    14161 attaaagatt attttgcaaa aaagaaaatc acagcttcac aaatggtcag tggaatgaat
    14221 catcagcaaa tgctttacag agatcaggtg aacgaaggaa cattcaactt attagattct
    14281 catgatactg ccaggatctt gaccctttgc caaggtaaca aagaattgat gaagtctgtg
    14341 atggccttta tgtttcttca aaaagggtct ccttgtatct attacgggac agaaataggg
    14401 atgactggtg aagatgaccc ggattgccgc aaatgtatga tatgggagaa ggaggaacaa
    14461 gatctagagc tattcggttt tataaaagaa cttgtttctc taaggaaaca gttgtctaag
    14521 attatttctg aaggttctac tcagtggcta atagtaaatg atcgtgaaga taagctctat
    14581 ttcacacgga aactagaggg acagatcatc tatgtttact ttaatcagtc aaaagaacct
    14641 tgggtagtag aacaggaaaa tgaggtgatt cttagtcaaa attgtcagtt gttagaagac
    14701 gggaaagcag agatacgaca atacggattt ttgatcatgt gttgaaaact gttaccggta
    14761 acaacaagaa agcgtttgca aatgaagatt tgtgcccatt ataataaggg tgtaacagca
    14821 cgttgaatac aaaggaggaa atgaagatga aaaaaagaag tgtgaaacag ttgggtttag
    14881 ggttaatctc tttaggaatc ttaggcggat tagcggcttg tggcaatggt aactcttcag
    14941 cagaagggga agccgatgaa ggaaaaacgt taacagtttc cgttgattct ggatataaag
    15001 attatataaa cgaaataaaa aacactttcg aaaaagaaaa cgatgtgaaa atcaagctag
    15061 tagaaaagga catgttcgat cagttggaat cattagcgtt agatgggcct gctggaaagg
    15121 gacctgacgt tatgatggca gcatatgacc ggatcggtgc gttaggacag caaggacatc
    15181 tggcggaagt aaaactggga aatgaagcag cttacgatga aacagacaaa gcccaagtga
    15241 cttatgatgg aaaaatctac ggagaacctg cagtaatcga gacccttgtt ttgtactata
    15301 acaaagattt agtcgataca gcaccatcaa cgtttaaaga tttggagaat ctatccaaag
    15361 acagtcgttt tgcttttgag tcagaagcag gaaaaaatac aggattttta gctaaatgga
    15421 ctgactttta ttattcctat ggtttaattg caggttacgg tggctatgta tttggtgatg
    15481 atggcacaaa tccttcagat atcggtttga ataatgcagg tgctgtagaa ggaatctctt
    15541 atgcaacaga ttggttcaaa aatgtttggc caaagggaat gcaagacata aaaagtgcag
    15601 gagacttcgc cagccagcaa ttcatgtcca ataaaactgc agcaatcatt gacggtccat
    15661 ggcaagcgca aacatacaaa gaaaacaata tcaattatgg tgtagccaaa attcctactc
    15721 taaataatgg acagccttat caaccgtttg gcggaggaaa aggatgggta gtcagcaatt
    15781 atgctaaaaa caaagacctc tctcaaaaat ggcttgatta tgtaacgaat caggaaaatc
    15841 aagaaaaatt ctttgaaatg gtaaatgaaa tccctgcaaa ccaacaagct agggaaacag
    15901 caaaggctaa aaacgatgaa ttaacaacag ctgtgattga acaatatgaa acagctcaag
    15961 cgatgccaaa catcccagaa atgggcgaag tttggacagg tgcagaaaac ttgatgttcg
    16021 atgcagcatc aggttcaaaa acaccaaaag aatccgcaga tgaagcagta aaaacaatca
    16081 gtgaagccat agaacaaaaa tactgattaa aatgataacc gtccattttt ataaaaaatg
    16141 gaacaggtgc ttcagataaa agtggcaaga gcgagatgga aaattatctt gctcttgttg
    16201 ccattatctt aaaagcagtt tgcggtttag caagtttaga gggggcattc agatgcagca
    16261 agataaaaca agcaatatca acgaaaaaaa aatcacgctt tgttcactta ttccagggat
    16321 ggggcagttt gtaaatggcc aagcttttaa aggtatcgtt tttttcgcca tattcgtcct
    16381 attcattggt cagatgcttc tgggcggatt tcatgcattg gtaggattgg ttactttggg
    16441 aagtatacca atggaagatc attcattatt tattttgatt gaaggcactt tgcaattcat
    16501 cattacaatc attttcttga ttttttacgg tttgaatctt ttagacgctt atcgagtagc
    16561 gaagatgcgt caagagggca aaaaaatcaa tcggacgatg aaggaagtca tacataatat
    16621 aggtgatgaa ggttttcctt atctattgac acttcccgct tatcttctca tgatttttac
    16681 gatcattttc ccagtcctag ttacattgtt cactgcattt actaattatg acttcaatca
    16741 tattccacca gccagtttaa ttgattgggt aggggctaaa aactttttta gtatcttctt
    16801 tttaagctca tatcgtaata ctttttttgc agtcttttcg tggaccgtga tttggacttt
    16861 atgtgcaaca actttgcaaa tcacccttgg tattctcaca gcggttgttg ctcaccagaa
    16921 atttattaaa ttcaaacgta ttttcggtat cattttctta ttaccatggg cggtcccagc
    16981 ttttattact atcatgagtt tttcgaatat attcaacgat agcgtaggtg ccatcaatac
    17041 tcaagtgatt cctttcataa accagcttcc ttttgtagat atcagtgcaa tctcttggaa
    17101 aacggacccg aactggacga aagtagcaat tatcttagtg cagggctggt taggatttcc
    17161 ctatatctat gtgatggtta caggaatctt acaatcgatt tcagaagact tatatgaagc
    17221 agcaaaaatc gacggagcaa atgcatggca gcgcttttca aacatcacgc ttcctgctgt
    17281 cttcctagtg gcagcgccaa catttattac acagtatacg gggaatttca ataatttctc
    17341 catgatctat ctgtttaaca atggcggtcc cggaagcgta ggcggaggag ctggttctac
    17401 tgatattctt atttcctgga tctataaact tacgactgga acttctccgc agtattctat
    17461 ggcttcagca atcacgttga ttatctccgt catcgttatc tgtgtgtcat tgctggtatt
    17521 taaaaagaca aatgcgttca atatggggga ttaacaatga aaaaatttca ttcgagtgct
    17581 cgattccaaa aacgactttc tcactttttt acttactttt ttcttttaat actgtcagtc
    17641 attatcatct atccgctttt gatcacagca agtactgcct tcaagtcagg aaatattgca
    17701 gcttttagtt tagatctttc aagtgactgg actttaggaa actttactcg gctattcagt
    17761 gaaacacttt acgggacttg gtataaaaat acattgatca tttctgtcct aacaatgatc
    17821 gtacaagtga ctgtagtaac tttggcgggc tatacttata gtcgctatcg ttttatcggc
    17881 cgcaaatcaa gtttgatgtt ctttttagtg attcagatgg taccgactat ggcagcattg
    17941 actgcctttt atgtcatggc tttcttatta gaagcgctcg ataagtactg gttcttgaca
    18001 atgatctata taggcggtgg aattccaatg aatacttggc tgatgaaagg atactttgac
    18061 actgtaccaa tagatttaga tgaatctgct aaacttgatg gggcagggca tttcaggatt
    18121 tttttccaga ttgtattacc gcttgtcaaa ccgatgctcg ccgttcaagc attatgggct
    18181 tttatgggac cttttgggga tttcatgtta gctaagttcc tgcttcgaac acctgaaaat
    18241 cagactgttg ctgtcggctt acaaacattt atttctgatg tgacaaacca aagagtctct
    18301 ctttttgctg ctggggcaat tttgattgca ctaccgattt gtctattatt cttcttttta
    18361 caaaagaact ttgttaccgg cctgacatct ggcggaacaa aaggatagga gcagagtatc
    18421 atgcaaacat ttccgttaaa ctatttttcc gcattacgta cgccaactca agtgtttgcg
    18481 ggacgcaaac tattatcatg gcctaaattt ttcttgatat ttgtattttt agtttccttg
    18541 atggtcatgc ctgtgactct tttttatgcc aatcagatcc aagcgattcc attagaacaa
    18601 tttctatccg ttcattcgct gatcgatgaa caaggaaccc aaaaattttc tgaacttgaa
    18661 ttatctgaaa ctgggttaca agcatcgcaa caaacgatag ctgtgacccc tgaaattttg
    18721 gtaggtgtgt ctttatctga gaaacaacaa tccgatcatg gaacttttat tgattttgag
    18781 aaggaacaat gggtgatcca acaaaaggat aaatctggta tacgccgcta tacgatgaat
    18841 tatagcccat ctttccaacc agattctgta cgtacgcccg aagatttcca acgattttta
    18901 gaaagagaat tttatgccag taatcgtcca acaatcattt tatcttatag tttaagtctt
    18961 ggtcttgtcc tatttgtcat gacgagtctc attttattcg gggcttcctt tttcttgtgg
    19021 atgacaagaa aaagccaact ttcatccatt catacattca aagagagtgc aaatttgatg
    19081 ctgaatgtta tgggaatagg ttccatggca gcagcagttg tagggtttat ccactttgac
    19141 tttatcttga tgctaagtgt ccaaacaacg ataactgtct tgctgctttt atgggttttt
    19201 gtcaaaacaa gattcaaaga taagcgtgtc gaatgacaag tttaagcgat ttatgcgaca
    19261 atgaatgtga aaaaaatgaa aaataaagta gtttttgaaa aatttctgaa aaaattaaac
    19321 ttcttagttg attcttttct tttttagtat taacgtaata gggtagtttt tttaaggagg
    19381 aaaatcatgt tagagaaaac tttatacaat caattatttt cacgttcttt ctcgctccct
    19441 gtcgaagtaa attattggga cggtacaacg aaacaatacg gagatacgga cactcctccc
    19501 caaatcaaaa tcaatatcca tgaagaaatc ccaatgaaag agattacaag taacgcatct
    19561 ttggcactag gagaagccta tatggatcat cgaatcgaga tcgagggaag tatccaagca
    19621 ttgatcaacg atgcttatca gcaagcaaac agctttttac gaggaaaaga ttatctaaaa
    19681 tggctgccaa agaaagaaaa acatacgaaa caaaaaaaca aagaagatat ccatgcgcat
    19741 tatgacttag gtaacgactt ttataaactt tggctagatc caactttgac ttattcttgt
    19801 gcttatttca atacacctga agatacgttg gaacaagcac aaatcaataa agtccatcat
    19861 atcttagaca aactctttat caaagaaggc gaaacgttgc ttgatatcgg ttgtggctgg
    19921 ggaacattga tgttcactgc taccaaagag tataatgtca aggcaactgg gatcacacta
    19981 agtgaagaac aatacgattt gattaccaaa agaataaaag aagaacattt agaagataaa
    20041 tgccgtgtat tattaatgga ttaccgcgaa ctaaaaggcg aaacgtttga tcatatcaca
    20101 agtgtaggta tgttcgaaca tgtaggttct gaaaatcttg aaggttattt caaagtggta
    20161 aaagatttat tgaaaccaaa aggaacagct ttgatccatg gaatcagccg acaacaaggc
    20221 ggtgcgacaa atgcttggat caataaatat attttccctg gcggttatgt ccctggtgtt
    20281 actgaattag ttgataatat tacaaaaaac gatttgcaac tgattgattt ggaaagctta
    20341 cgtcgtgact accaattgac attagaacat tggacaaaga attttcatca agtccaagat
    20401 caagtcacga aagaaatggg tgattccttc tatcgaatgt gggatctata tttacaagct
    20461 tgtgcagctt catttgaatc aagtaatatc gatgtgattc aatatttgct tgttcaacct
    20521 ggaaacaatg acatcccaat gcatcgtgca taattgaggc aaaagtactg tttaaagact
    20581 atttaaaaag aagctaagtt ttatgatgct ccagaagtga acttttttgt ctaacttcta
    20641 ggattgtctc taaagcttag tttctttttc tttatatttt cataataaaa gtttggttct
    20701 ttaattttta aacatgacag aaaatttttt cttcgttata cttgtaatag aatactattt
    20761 tataacaaag gggatcgaat caatgaaaaa aactgttatt tatactagtt tatttgcagc
    20821 tttgttttta gctgcttgtc aatcaaatac caatcaaggc acatctggga atacgtcttc
    20881 cagtagcgaa cagcgctctt cacaggtatc ggactcctca acaaaagcaa gcacatcttc
    20941 gtctagccag acaaaaagtt ctagtgaagc aagtactcag tcagatatca aagtgtctgc
    21001 agctcgtgcg atcgaattgt tccaagataa atacccagat actgcaatta ctagtttgga
    21061 attagatagt gattggggat cttacttcta caagatagaa ggtgtcgatg atcaaaaaga
    21121 atacgaagca agaattgatg ctcaaaatga aaaaatggag acagagaatc cagaaactct
    21181 agatcgagat gaacaaaatg gtcaaaagaa aaaagaagat ggtctggatg ttgataaatt
    21241 gatcacgatt gaggaagcag caaaaatcgc cgtcgacaaa gtaggaagcg gtacggcaac
    21301 agattgggat ttggataaag atttaggtac tacttattgg gaagtcaaag taaaagacgg
    21361 caatcaaagt acatcagtca agatcaatag ccaaacaggc gaagtactgt caactgaaca
    21421 agatgattaa gaatttcttc ggaaaacaag agttgatttt tcttttagtc atgatacact
    21481 agacaaaata acttgtttga aggagcgatt tacttgagtt tagaaacgac ctttgccaat
    21541 catatctttg ccaatccttt gatgaatgca tctggtgtcc actgcatgac tacccaggaa
    21601 ttagatgaac tggctcattc agaagcagga gcatttatca ctaagagctg tacgatcaat
    21661 gaacgaaaag gaaatcccga accacgctat tttgatgttc ctttagggag tatcaattct
    21721 atgggacttc caaacttagg tttttcttat tatctagagt atgctcttgc gtatgaaaaa
    21781 gtgcaggaaa accaaaatca accgttattt ttttccattg ccgggatgag tgtccaggaa
    21841 aacttggaaa tgcttgagaa aatagaaaaa agtgggttta atgggatcac tgaattaaat
    21901 ttatcttgtc ccaatgtgcc tggaaaacca caactagctt acgattttga ggccacttat
    21961 gaaacactga aagaagtatt cagcatcttt tctaagccgc taggaatcaa attgcctcct
    22021 tattttgatt ttgctcattt tgatcagatg gctgatatct tgaatcagtt tccattgacc
    22081 tatgtcaatg ctatcaacag tgtgggcaat ggtttgtata tcgatacaga acaagaagca
    22141 gtagtcatca aaccaaaaga agggttcggc ggcattggcg gagagtatat caagccgact
    22201 gctttggcga atgttcgcgc tttttataca cgtttgaaac cagaaatcca aatcattggt
    22261 acaggtggga ttcggacagg acaagatgca tttgaacatc tgctatgtgg cgcaagcatg
    22321 ttacagattg gtaccgagct tcataaagaa gggccggaaa ttttttctag aatcataaaa
    22381 gaattaacgc agattatgtc agaaaaagga tatacgtcaa ttgacgaatt taaaggcaaa
    22441 ttacgcacca tttcatagca aagagacgaa ggtcatgatt gatcttcgtc tttttttata
    22501 aaaaacactc gtctgttcat tcctgtgcaa gcgtactcat tgtatgttag acgaacttgt
    22561 gggaaaataa cagaggcaaa aaggaggata atatgaatga tgcaacagaa ttagcaaaag
    22621 agcttaaaga aaaagaattt agttttcaag aactagttac ggatatacag aaaaaaataa
    22681 agaagcaaaa tcatgaattg aatgcgtttg tcgcgcttga accattcgag agtaattccc
    22741 acgagctatt gattccccag tcagaaaaag ggccattggc tggtatccca tttcctttaa
    22801 aaatgctcgg tcaagaaaaa aagggatggc tagctacttc aggatctcgt ttatttgaaa
    22861 cacaccgagc ttctcataca tctaattatg tgcggcaagc agaagcgata ggtctagttc
    22921 cttttggaca aaccaatgcg ccagagtttg gtttcaaaaa tattacagac ccagtcatct
    22981 atggcccagc aagaaaccct tggaaccttg aatgtacacc gggcggatca agtggaggag
    23041 ctgctgctgc agtttcatca ggaatcgttc ctttagctgg tgctagtgat ggcggtggtt
    23101 ctattagaat acccgcttcg ttttgcggat tgattgggct gaaaccttcg cgagggacga
    23161 tgccagttgg tccatatgct tggagaggat ggcaaggagc tgctattgat ttcggcttga
    23221 cagtttctat gagagacacg gaggctttat tttatgggat gagaagtatc cattccggtg
    23281 cgccatatca agtatcgcca gttgagtggc aaacacatcc aagaaaaaaa cggttgaaga
    23341 tagctttttg tgttgattca ccgatccact cacagattag tgaagaggca gtacttgctg
    23401 taaaaaaagc tgtagatttc cttggaaaag aagggcatga tttgacagag attccttacc
    23461 cactagatgg tcgtaaactg atcacgtctt attatcagat gaatggcgca gaaacagcag
    23521 caatgatccg ctcgattgaa acaggcatcc agcgagctgt cagaaaagaa gaacttgaac
    23581 ccatttcttg gactttgttc caatatggtc agaagctctc tgccgctact tacatcgatt
    23641 ctctgcatgt atgggatgaa gcagcaattg tcatggaaaa cctacatcaa gaatacgatc
    23701 tattcctttc accaacgact gcatttaccg cccctaaaat cagcgaagat ttgcaaagtg
    23761 atgcgataag agcacagatg gaacacatca gtgattgttc tgaagtagaa ggtttagacg
    23821 ttgtttcttc catgtttgag gagagcttga agatcacacc ttatacacag ttggctaatc
    23881 tgactggaca accagcaatc agcttgccta ctcatttgac aaaagaaaac atgcctctag
    23941 gaatccaatt tatggctgcc agaggaagag aagatttgct atttcaaatc ggctatctat
    24001 ttgaagcaaa tcatcagttc catttaccaa atccatggaa atagcagaaa caaggagaag
    24061 aagaatgaag aaaaaaagat tgtttgctct aataactagt gcctttttta ttttaagcgc
    24121 ttgcggtaca gctgccgcta atcaggaaga taacagctgg agtaatgtag aaaaaaagaa
    24181 agaattagta gtagcgactt ctggcacact gtttcccgca tcttattata atgatcaaaa
    24241 tgaattagtt ggttatgatg tagatttggc aaaagaggtg gctaaacggt taaatgtcaa
    24301 aatctccttt aaagaataca acgtggatgg acaaatcact tctgtttcaa aaagagaatc
    24361 agattttgct gcgaacgatt ttggtatcac aaaagaaaga gaaaaaaaat tctccctttc
    24421 agagactttc aaatattcat ttgacagtat gatcgtacga aaaaaagatg attcaggaat
    24481 ccactcactt gaagatctta aagggaaaaa agcagctggc gaacccaata ctagctatat
    24541 gcgtttagcg gaaaaacacg gagctaaatt agtcacatat gacaatgcca cgaatgatca
    24601 gtatttaagc gatgtagcaa atggtcgaac agatgttatt ctaaatgatt attatctgca
    24661 gaaaatggcc gtatctgctt taccagatat ccctgtaaaa atactggaga acgtttattt
    24721 caatgaaaac gaaagtggtt ttttattgaa agaaggaaat gatgctctga aaaagaaaat
    24781 cgatggcgta ttaaaagaga tgaaagaaga tgggacgaca aagaaaatat ctgaaaaata
    24841 ttttcaaact gatgtttcag tcaaaccgaa agaaacgatg gctgagtcgg tgagtgagtg
    24901 atgtactttc ctctaattga tttttccctc atgtggactt cacttccttt cgtactgcaa
    24961 ggcttggtat acacattagg gattggcttc gtgtcgtttc ttttaggaaa tctggtaggg
    25021 ttgcttttga cagttttagg tcttttggat tggctgcctc tgaatgtatt tattcgtttt
    25081 tatttatcgt tctttagagg cattcccgca ctagtcctgc tgtttctgtt atattttggg
    25141 ttaccttatc aattaagtgc cttaacggct tcagtcatct gctttacgat taccagcagt
    25201 gcatttattg gtgaaatcta tcgaggatca ctagcaggcg tttcttcagg tcagtgggac
    25261 gctggtttag cttctggttt ttctttcttt ggggtattga aatatatcgt tttgccgcaa
    25321 gcttttcgaa tctcagtacc ggcactcagt aacgtagcta tggatctagt gaaaggtact
    25381 tcgttagcag caacaatcac agtgccagaa atatttcaaa aagcaaagat cataggcggt
    25441 cggacattcg attatttttc tctctatatt ttagttgcac tgatttattg ggtcatttgt
    25501 atcgggatcg aaaaagtgca acagtattta gaaaaacgtt ctatgcatca gtcaatctga
    25561 aaaatagaaa tggtgctagc gtggctggca ccatttctat tttttgtttc ttgtatattc
    25621 tgcctagtat tttaaaacca tttcatgtaa aatgtaaatc gaaaatatgt tcggaggtag
    25681 aaaacatgaa gaccccgcta accatcgaaa tagaatcctc gttataccaa tattgcatcg
    25741 agcaaggcgg cttggttgta gaagaagtca cgatgcctga tgaccaagga attgtagata
    25801 cgcttagctg cttgacaaaa tttgatggaa gccgagaatg gcgatgctat gagctgaaag
    25861 tgacaaaagc agattttcgc tctacagcca aactgtcatt tgttggacat tataattatt
    25921 ttgttttacc aagtaaacta tatgaagaag taaaaactga aatccctaca ggaataggtg
    25981 ttttagtgta tcgtccgtac acggttgaag aggagatgcc tgcctctggt acatttctga
    26041 ttgcgaaaaa agcagcaaag aaagagcttg ctgtaccgga agaagctttg acaaaccgct
    26101 tcatggcttc tttattcagg gaagtaagaa aagcaaagca aatggagcga ggcgtaaaat
    26161 attttccaac agatcaattg tacaaagaat tgaaaagacg ttcagaaaat caagatccat
    26221 tttctaacga acgatattat gaacggtttt tagaggaaat agctagtcag gcaatcaatg
    26281 agttgcaaga agaagttatc gcgcttcagc atgattatga atatttgagg caacaacagc
    26341 agatccgtcg gttgcctaca gagccattgg agtgaaaaat atgtactatc cttatttaag
    26401 aggaaaacaa tttgacctat tagcattaaa agaagcactg tcgcgaggat tgctctccaa
    26461 taaaatccaa ccagtgatcg aaccagtacg tgattccgct acgcttaaaa atgtgatcga
    26521 attatttcaa aaaaagcacc atcgaatcgc tgtgatccaa aatccccaag taggacaatt
    26581 caaattattc gatcagcatg tgcacagttg gacagtcaaa gaaaatagct ctgtcgtccc
    26641 tgcacagatc ttaacgccag aaaatctcag tgaagtactg gattcacctc cagcgtttct
    26701 tgttttcgat ggacagcact acccaaaaga tacagaggtg tggaaacagt tggcaggagt
    26761 tgattcgaaa tttttgatac cagatactag tcgctttcgc atctggctgc ccgaaaacaa
    26821 aattgtgatc cgtgactctt ttcaaacgag aaagcatgtt gaaagttatg cagataaaac
    26881 agatgacttt tttagtgatg actatctttt tttccacgca gacggatata ttggattttc
    26941 tgatttcacg atcgaaggta gccgttattt cgataaaggg ttccctagcc gagcgcttgc
    27001 tatccatcta acgtatattg atgcttacgg caatatacgc gtgaaacatt ttgtctctga
    27061 cagtaacgac tctgctaaag accaagcatt gaagtttctt gaagcaggag ataaaatgaa
    27121 aaaatggatc atgcgtcacc atcatcaact cttgattact tcaggaatga ttgaattatt
    27181 ggctctttac cagcaacaaa aattccctgg actgggagtg ttgaaaaagt ggtcacttat
    27241 gcatcatttg gaacttatta gtcacctgct agatcatcca aaagattggc ttaaatatta
    27301 ttcaaaagtt caggaactat atgaagtgat ccaatgatta gataatgtaa atgaaaaagg
    27361 aatagaaaag aggaaactgg atgtatattc ggcaaacaag gaaagaagaa gtagaagaag
    27421 tggtagaaat cattaatgcc gcagcggatt tcattgcttc gcaaggctct cctcaatggc
    27481 aaaacgggca gaaaccaaca aaagaaacga ttttgaacga tattgaaaga aaagaaagct
    27541 atgtattaat agtggaagat caaattgctg gaacagctgc attagtctca agcgtggatc
    27601 ccgtttacac aaaaatagat ggtagttgga aagaatcaac tggtccttat ttatcgattc
    27661 atcgtgtcgc tttagcagaa agtactcgag gaaaaaaact agcaaaaccg ttcttagaac
    27721 atttgttgac gattgcagcc agcaaaaata tccaagatat ccgtatcgat acttatccag
    27781 ctaatgaacc gatggaaaag accatctatt ctgctggatt cacttatcaa gggatgattg
    27841 aatttccttt tgaacacggc gaaagaaaag catatcaaat aatcatcaat tgactataaa
    27901 atcatctgag caaagataaa gacattaaca ctactgaaaa aaacaatcat atgatagcca
    27961 agaggttgta acagaagtgg ccagcttcaa aaaacaagaa agaatttccg aaaatgcttc
    28021 tcaaattttt gtggaatttt agcgtatttt acgaaatagc ttctttctga aactcccttc
    28081 atcgagaggt cgtgacatag cttttgtcac gacctctcgg cttatcctac gagtattatt
    28141 cgatacattt atatcaataa tccttttttt attttatctg cagcttcttg gaacgctcca
    28201 tcgtttgaca cgactaaaag tgaggggata gctttcaaac gtttcaactg tgctaaatct
    28261 tctacataaa ccgccagtct ggctgaaatc tgttcagatg aatctccacg ttttttcagg
    28321 cgcgattgca atgtttcttt agagatcgta ataaagatag gacggactac cgtcccgaaa
    28381 tactcatata aatgccaaaa accatttgct gtcaaaacgg cgtaacaatt tcctactgtc
    28441 agtttctttt taatttctgc tttactggaa ccatatttat gttgagcata ttggtcccac
    28501 tctgcaaact catttccctt gatcatctga ttgaatgtat tgtcagaaac aaaataataa
    28561 tcctcttgat ctttttcccc aggtcttggt gatcgattcg tgtaagtaat gatcttttgt
    28621 tccggctgaa aaatagcttc tgcgagtgaa gtttttccag aaccagaagg accgataaat
    28681 acatagcaat aattcattgt catttctcct ttgatgattg aacaagtgaa aaagctttgg
    28741 aaaatatttc caaagctttt aaaagtaact ttgctttttt gtatattata ccagcaagcc
    28801 agtcacaata gcacttaaaa agctgactaa agtcgctgtt agcaaaattt tcaatccgtg
    28861 ttttgcgaca agatttcctt tttcttcatt taatcccttc atcgcaccag aaatgatccc
    28921 gatagaagag aagttggcaa atgaaacgag gaagacagat ataattgctg ttgtacgctc
    28981 agtaaaatgg aaattaccat ttgctaattc tgtcatagca acaaattcat ttgtaaccag
    29041 tttagtcgcc atgatactac cggcatccac tgcttctttc catgggattc cgctgatgaa
    29101 ggcaagaggg gcaaagatgt aacctaggat ctcttggaaa gtgatgccga atatcccgtg
    29161 gaagatagca ttgatcatgg caatcaaagc aacaaaaccg ataagcatag cagcaaccgt
    29221 gatcgccaca tggaaaccat caagaatgta ttctcccaac atttggaaaa atgtctgttc
    29281 tttgttttct tcaatgatca gctcatcttc tttttcttct aatacatagg gatttacaat
    29341 tgaagccaga atataaccgc caaataagtt caaaacaagg gcagtgatca catatttaga
    29401 atcgatcagt gccatataag atccgacgat cgacatagaa actgtagaca tagccgatac
    29461 actcatggtg aacaaacgtt tctcagatag gaagggtaat tcctttttta tggaaataaa
    29521 aacttccgat tgtcctaaaa tagcagaagc tactccatta taagattcca atttgcccat
    29581 cccgttgatt ttacttaatc ctagaccaac agctttcata aataatggaa gaatcttgat
    29641 atagcgtaga ataccgataa tagcagaaat aaatacaatt ggcatcaata cggaaagaaa
    29701 gaaaggtgca cttcctttat ttgctacacc ggcaaaaaca aagtcaacac cttgcccagc
    29761 aaaagcaaga agatgatcaa acatttttgc caatacagaa acaaccgctg taccaaaagt
    29821 tgtacgtaat aatacgaaac caagaacaag ctgtaaaacg aacatcacaa ttagtggttt
    29881 caatttgatt gcttttttgt tactgctgat caaaaaagca agccctaatg tgacaaataa
    29941 accaataata cctaataaat aactcaaata atcactccta ttccaaattc cgttttattt
    30001 tacctgtttt gcaaataaaa tactaatctt tagtgaaatt ttcattactt ttttagagtg
    30061 aaacgcattc attttccatt agaaaataaa gcgaacaaaa taaaaggttt aaaaagtgta
    30121 acgtcttagt aaagtctata aaaaaacgaa actatcgatt aagctaatag tttcgttttc
    30181 aacatttata agtaaacttt ttctattggt aatatagatt ttcggaaggg tagacaggtg
    30241 cgcaggtaat atcgattcct agttttttca atgtttgttc atcattttta ttgaccatca
    30301 cagtagagtg ggcttgtgct ccctcaagtt cagctagttt atcataagca acttgagcga
    30361 ttggattcgt tactgcactg attgataaag cgatcaagac ttcattgatg cttagtgcat
    30421 ccaaagagga atgaagtgtc tttgatttca atccttgtat tgtttcaaga actaatggtg
    30481 acaataaagg aatgtcatct gcgatatggg ctaaatgttt tactgcattt aagataactg
    30541 ccgctgacgc atccatcaat gaacttgtac gcccggtaat gatgacttca tctggtaatt
    30601 cgattgcaat cacagcagaa ggatcttttg taggactttg cgcttgaatc ttatctgcat
    30661 agtcatgggc agggactacc acgtttcggt cttcaggacg taaaccgact tcttccataa
    30721 tcagtttgat tcgattaact gcttcttcgt cgatcaatcc ttttttgaag tcgcattctg
    30781 tttggaaata acgacggatg atttcttgtt tagaggcttc ttggacaacg gtatcatcca
    30841 cgatcccaaa tcctacacga ttcacaccca tgtcagtagg agattgataa acagattctt
    30901 taccagtaat tttttcaata atacgtttga ttacaggaaa tgtctcaaca tcccgattat
    30961 agttcacagc tactttattg taggcatcaa agtggaagga atcgatcata ttgacatctt
    31021 ttagatcgac tgtggctgct tcataagcaa tgttcagcgg atgtttcaac ggaacattcc
    31081 atactgggaa agtttcgaac ttggagtaac cagctgcatg tcctttttgg ctttcatgat
    31141 acagttggtt caaggaagta gcgagctttc cacttcctgg gccaggagct gtcactacaa
    31201 cgattggttt agttgtttca atatactcat tttttccaaa accatcttct gagacgattt
    31261 tttctacgtt gactggatag tcttcgattt ctgagtgttt atagaccttg atgtttcgtc
    31321 tttctagttt attgataaag actttcgtgg caggctgtcc actatagcga gtgataacga
    31381 cactgttgat taataagcca taaccacgta attcatcgat taaccgcaag atatccatat
    31441 cataagtaat cccataatca ccacggatct tattacgttc aatatctcca gcatagacgc
    31501 aaatcagtat ttcagcttga tctttcaatt tttgcagcaa tttgattttc gcatcttctt
    31561 caaatcctgg aagtacacgt ttcgcatgct tgtcgtcaac tagcttccca ccaaattcta
    31621 aatataattt gtcatagtgg ttcactcgtt ccaaaatata cgctgactgc tcttcaatat
    31681 atttttctga atcaaaacca atttttttca ctaggttccc tccttaagta ctaaagcatt
    31741 ttttcatttt tttgaggatt cgtcaactgg aagagcgaaa ttcctcaaaa aaacaaagaa
    31801 aatggtttaa accaacttgt ctagatagtt attcattggt atgatagttt ttgataagga
    31861 aggtgctaca tgaaaaaaag acagaaaaag aaaaacgcat ataaacacta tatccgttcg
    31921 atttttaccg gttatgaaag aatgcttgaa gatcccgaat tggaacaatt gacgtttact
    31981 tatctaaacg aagaaacgca gctaactcgt gatgagcatc agcgcattca tttcacaaca
    32041 agagatctgc ctagtaaata aaaaataaga taaaggtcat cggattcgat tctgtcctat
    32101 cagatggaaa gactagttga tcgaaaaaaa ggctgtacca aattttggtg cagcctgttt
    32161 tatggagcat tgcccgctct tttttataac aattttttac agaaaatggt actattgaag
    32221 tattaataag tgaaaaacag atgagtaaga ggaggcaagt agtatgaaag agccagatac
    32281 aaatgcaaat tatgagccag acgaactaga ggagacgaat gcggatcagg atacaggaca
    32341 agaatcgtct tctttttacg atatcaaaga aaaagcaagc atgaatcttt cccaattatt
    32401 agaagactta caggcttttg aaaaagctgt ccgcgaagaa gatatccctg agatctaccg
    32461 tttatacaat ggccgattga atgaagaatt aaaaagaagc tcaaatgaaa atcacgagat
    32521 cgatcaattg ctgatgcgta agatccatga tcgtttttta caggaatttc cttttatgga
    32581 acaagtagaa aacatctcgc caacgatgag ctattacaaa atcggcactt attaccatga
    32641 tcggcccacg gtcggtattg atgcaagtct gccagaaatt tttgttttgc ctaagatcga
    32701 tgaagagtgg gagaaatatt cccaaccgga gtcaacggac tatgacaaaa aaatcaatga
    32761 gctagacgca aaggtgatca ctgctcagac agaaattgaa cgtttagatg aacaaataaa
    32821 agaaatcaat cgacaaatga ctgatttgaa cgacaataaa ggattcttga atcgtaaaaa
    32881 aatcgaggaa gaaattcaag aattagagaa gaagaagcaa gtactatcta atgaaaaatt
    32941 aggctggctt ccttatattg agacgcctga aacaatccag cagcaaaaag aagcattgaa
    33001 gcaagaagca agagcagacc agcttcgtgc agccatcgta gaaaaagaac aaaggcaaat
    33061 cagacgctat ttcggtagca aagagggatt cggtcaagca atccatgaat tcttgatgaa
    33121 ttatcttggc aatgagaatc ctaataatca atctaatgaa ggaggttccg agtatgaatg
    33181 aacacgatga agcagaatgg acaaaaaatg aagaacaaac agaagatcat gaagaaacga
    33241 acacttcatt ggaagaacaa acaagtaatc ctctggatga cacagaagaa atccctatgc
    33301 tagaggaaac aaaaatacac gaaaaagaaa aagtaactcc gacgaatacg aatactgcag
    33361 aaaacaccca tgcttacgaa ataactgaaa atcccgggta tttagaagga aaagagcaag
    33421 atcatcaaga tatcgtcagt ttgattgaaa cagcggaagc agaattagcg gatttacgta
    33481 tgagaaaaga tttgatcgaa tcagattttc cacaattatt agaatcatat gatcgtttta
    33541 tattgaatga agaaccaatc tccacgatcg gaaagacaag cctgatcgaa tacttcacgt
    33601 atgaattact gaaaccgttg aatgatattg gtctggaacg gtcaaattca gcttatgaca
    33661 catggaaaac aagacatttt tcgatcaatt atacgttgaa tggacaaaac gaattagtct
    33721 tttcctttgt attaccgacc atcgatcaac gataccaagt ggaatcgatg agtctcctaa
    33781 acgtatcacc agagacaatg gaaatcaatg tccaagatga ccgggtgctt tctttgatcc
    33841 gacactggtc agtggatcga gtattctctg cagggcagat cacgatattc aatcacaaat
    33901 tgaatcaatt attagcccat gcaagaacac ttggttttac cgttaatcag acattactag
    33961 acaatacgaa gccacttcgt ttgaatcttc agagcgaatt tgaattgacg aatgaagtat
    34021 tggatgatat ttttatcgtg gcaatgaaaa atccatccta cgatatggaa aagatcaacg
    34081 aaactactta tcaagtacga ttagataaag gacagtcttt aacgataaca acaaacgaaa
    34141 aagatcaaac agtcttgtcg atctcatctg gagactaccc acgatctgtc attgatttct
    34201 ttatcaatta cgaattcttg gtcccattaa tggtgagaaa gtcctgattg gataagttgg
    34261 attaccagat gtcattcaga taattctgtt ccaaaggact tgcggcagtt atccagaata
    34321 attgtcacaa gtcttttctg tatgtactaa atggacgtga ataacttgct gatgaaggag
    34381 ggatttcatt aggaatgtcc acaaataaaa tagcacagct tagcttattg tctgctgctt
    34441 gtgtagcagg taggatcgct tttcaattta ttccgaattt ccagccaatg actgctattt
    34501 ttttatttat agtactttac ttaagcttaa aagatgcgtt aattgtcatg agtctttcta
    34561 ttgcgatcag cagtttttat tttggtgttg gaccatgggt catcggccaa tggatcagct
    34621 atactgttgt tctgagtttg ttttcaatcg tctgcttgag aaaaacagtg caaaggaatc
    34681 tatggttaaa gggagtctgt ttttttctgg cgggcatggt ttacggaata ggtatgaccg
    34741 tttttgatac gctgttatat cgtttgcctc aaccttggat ctattacctt caaggggtgt
    34801 cgtttgattt gatgcacagt ataggcaatg ttgtgttctt tcttgttttt ctgccagtcg
    34861 tcaaacgttt ttacaatcat tcaggaggaa aaaatgaaaa aaataattta tagtttgctt
    34921 gcaatgagtg tcagtatact cattttgaca agttgcagta caacctatac acaatcggct
    34981 tccaaccaaa aggaggaagt aaaaacatcg caaaaagcaa caatcacgtt acaagaaaat
    35041 ggtcaaaact tttcggaaaa agaagtgttc ttcaaaaaag gcgatgattt actgagtatt
    35101 ttgaaacgaa attttgaagt caaagaagat aacggcttca tcacttcgct tgaagggcac
    35161 tcacaggatg agaaaaatca actctattgg atgtttactg tggacgggaa aagtgctact
    35221 actggtgcca aagagatcaa attgaatgat ggacaatcgg tcattttcaa tttgtctaaa
    35281 ctataagttt cataaaaaac tgttaaaggg cgaatattgc cataattcag tgagttcagt
    35341 tgatgaaaga aggaaaataa catggaaaat tttaaaaaaa gcggaatgtt ttccgtaatt
    35401 gctgctctag gggctaatat tctagttgct atcagcaaat ttgtcggcta tgcaatcagt
    35461 ggcagtgccg ccatgctaaa cgaaagcatc cacagtatcg ttgattgcag caatcagatt
    35521 ttgctgttat tcggtgataa acaagccaat aaaggacaga gcgagttgca tcaatttggt
    35581 gaaggacgag caaaatactt tttcagtaca atcgtcgcaa tgatgctttt cttcggcggt
    35641 ggggcacttg gggtgatgga agcttttgaa aagttgacgc atccatccca tgaagtgggt
    35701 aatccgatca ttgttatagc aatactgtta tttggtttgg taatcgaagg aagttcgtta
    35761 cgcgtggcaa tgaaagaaat caaagaattg aatactgaaa aactttccac gatgcgcttt
    35821 ttgcgcgaaa gtcgacacag tgaaatactg attattttta cggaagactt gtgtgctgta
    35881 atcggtttgg tcttggcttt agcaggaaca atattgactt atgcaaccgg gattgctgca
    35941 tttgatgcga tcagcggatt gctgatcggt ttcttgctga tgggagccgc cattttccta
    36001 gcaaaagaat tttatagtct gatcatcggt gaaagcgtga cagcaagcga tttatcaaaa
    36061 atcaagttag cttttgaacg tcctgagatc agtcggctga tcgatataaa aacagttcat
    36121 ttaagtccaa cggagatttt agttgcagca aaagcagata tcgttggtaa caaagagaat
    36181 gaagcttact cggtcatcaa tgatattgaa aaaaatatgc gtcagtctct tcctgacaag
    36241 aagatgtata tatacattga aacagataaa tatgacccaa attattctcg taaataaaac
    36301 gtttattcat gaattgaagc aaaaatgaga aaaatataat cttgttttta aataaaacgg
    36361 ctacaattta gcgaatttat gttacaatga gtccgctgtt tatttgttgt aattaaagga
    36421 gatattttaa tgaacaaaaa gaaaagtgcg ccatggcttc aagctttgca tgcagtgatg
    36481 ccactttgta taagctatat accagtagga ttagcttgcg gagtattgtt gcaaaaagtt
    36541 ggatttgatc ctctcttatc aggactgtta tcgattctgg tcttttccgg tggcgcgcag
    36601 tttttagttg catctatgct tacgacgcaa gcatcatttg caacgacatt attgatggtt
    36661 ttctttttag aattacgcta tacattatta ggagcaagtc ttgccggttt tatgaaaaaa
    36721 gaaaagcgga cgtttttggc tgtcttttct caatcactga atgatgaaaa ctatgcggtg
    36781 aactacttaa agttttcaac tgacccttcc tggaataaaa gaaaggcttt atatgtcaat
    36841 tggttctcaa tgactgcatg ggccggtagc aatatgatcg gtaatttttt cggctcggtg
    36901 attcgagtag atgctgacct tgtccatttt gctttgacgg ccatgttcat tttcatgttt
    36961 atcatgcaga tgaaaagcgc actactgatc tttacaggtt tattctcagg cgtattaggg
    37021 gtcgtattca tggtattatt ccaaaatact ttcggattga ttgcagcaac agtcattgct
    37081 tcatttgccg gatttatgct ggagaaggca ttcaaaaaag aaaaagctaa gaaactaaga
    37141 gaccgcggta aagatgtcaa tgagccgctc ttcaacttcc cggaacagga ggccaatcac
    37201 catgactaaa ctatatttgc tacttttagt tgcttgtctg ttcatcgtgg catatatccc
    37261 gcgcttgttc ccgatgcttt attttactca tcgaaaagtg ccatcctggt tcagtgactg
    37321 gatgaaatat gtaccggtgg cattatttgc ggcgttagct tttaaagatg ttttcattac
    37381 tcatgaacat ctggatattg cttggaatat caaaatagct gcaatgattc tagtagcagg
    37441 cgtggcttac aaaacacgtt cgatggcgtt gtcagttttg acaggacttg cgtctgtctt
    37501 tttgctgtct atgctttaaa ctgttttatt ttattaaaaa cagagattgc gacataagtt
    37561 gttcaaactg atctatccga actgcatttg caacagtcaa ttctggatgc aagtttattc
    37621 gtagggataa aaaagattag tgttggctta tgatgcaagc tcttttttat tttaggaatt
    37681 agagagggat ttgtccttct atgatttttt gctataatag ggaagatgtt tattttatga
    37741 aagaatagtt gagggaattt aaatgaataa aaaattgatg caaggaacat tttggctaac
    37801 ctttgctaat cttctatgta aagttttagg ggtagtctat ttgattccct ggctaagtat
    37861 gatggggaac aatcaagatg gtatgcttgc tacgacattg tataatgttg gctatcttcc
    37921 ttatggattg ttcctgatgc ttggtacagt cggatttcca aatgcgattg caaaaaaagt
    37981 agctgtagcc acaaaagaag gagataacgc tgcttgtcgg ctgattttta gaagtacgat
    38041 caatatcatg tttgtcatcg gtatcgcctc tgctgcactg atgtatttat ttgctccttt
    38101 actagccgga atcagtccga ttgctaacgt taataatggg atactagcta tcagaagttt
    38161 atgcccatct ttgattgcta tcccaattct tagtgcaatg agaggatatt tccaaggaaa
    38221 aaatgatctg cggccttatg gaacttcttt gattatcgaa caggctgtgc gagtgatcgt
    38281 tatcttggct ggtacttatt acttgcgcgt attgactgac ggaaccatat tagaagctgt
    38341 attgatcagt acagtcgctt ctttcttcgg tgggttagct gcgattatcc atatgtatat
    38401 cgtcggacgc agaaaagact tcttcgaact taaagatttt ttgatttcca gccgttattt
    38461 cgaaagagaa aaccgatctg cctctgtctc tatcattcgg gaaacactac cgtttatttt
    38521 tgtcggctca gtcattacta tcgttcaaat gatcgaccaa gtaacgatga aaccactgct
    38581 tcactttttc cgtccagaga tcgcagatca gcaactggaa ttcttattca gccgtgcttc
    38641 tgtcaatcca aataaattga cattgatcct gatctccatg gtaggaacag tagctataag
    38701 cagcttgcca atattaagca cgatgaagaa aaaagatcgg atacaaatcg aaaaaacagt
    38761 aggagatagt ttttcgattg cgttattgat tcttcttcct tcattgactg gaatgtcttt
    38821 attagctgga ccactataca cattgttttt tggctatgat cctgaaagtg tcggatattt
    38881 ccaaatggct ttgctagctt ctttgttttt ctctttattc acgatcctat ctacgatgct
    38941 tcaatctttg aatcaccatc gttttgcgat ccgattaact gtagaagcaa ttatcctgaa
    39001 agtcatcttc caagtaatcg gattaggatt agttggcgga tacgggatga gcttatcaaa
    39061 tggcttagca ttcggtattg tctttgttcg cggctatcac tttatgtgca aagaataccg
    39121 aatagcacct ttagcaaaga tcagcaattt tttcttaaaa actttccgct ccaccctgat
    39181 tatgcttgca gtatgttttg ccgttttctt tttgctgaat cagcgattgt caatggaatc
    39241 aaaaagctat gcaatgattt attgtgtggc tgtaggaagt attggcggct tagtattttt
    39301 attttctcaa ttcggaaaaa atgggtttcg aatgttgaaa aatgttaaac atcatagcag
    39361 aagcaaagaa taggttaact aatcgttttt tgctgtcact tgaaaaacgg caactcgtat
    39421 gattacgctt gtcgtttttc tattttccaa ttttagtttc atatctaatc ttacttatga
    39481 tatagttata aggtctggaa aaattctttg aaacgaggaa attaaacaca tgaaacttgc
    39541 agtagttaca gatagttcgg catatctgcc ggaacgtatc aagaaccatc ccgacttatt
    39601 cgttattcca atccctttga ttatggatgg gaaaatttat aacgaaggaa tcgatatcga
    39661 agcggatgaa tattatggac ttttaaaaaa cagtaaagat tttcctacta cttcacaacc
    39721 tgtcgtaggg gaagttttgg gtttatatga ggaattgaaa gagaaagggt atgacacgat
    39781 tttaagtatc catctttctt cagggatttc tggctttgtc aacacattat ttgcgatgaa
    39841 agatgacatc agcggagtaa cggtcattcc ttatgactct aagatcacta gtatgccgat
    39901 gggacacatg gtagaagctg ccttagactt aaatgatgaa ggtcagtccc ttgatgaaat
    39961 acttgcacat atcgatcgaa tccgagataa tacctacgct tatctgattg tagatgattt
    40021 gaacaattta gtacgaggag gacgtttgac aaatggtgca gcgctgattg gcagcttatt
    40081 aaaaatcaaa ccgatcctga cattttctga agggaaaatt gttttattcg aaaaaatccg
    40141 ttcaagtaaa aaagcatttg ctcgagctga agaaattatt ggtagaagaa ataacgaaat
    40201 acaaccgcca gtcaaacttt acgtgataca tgcaaataat ttagaagtag cgattgcgga
    40261 gaaagagaaa ttgcagaaaa aatatccaaa tgcagaaatc gaaattggtc atttcggacc
    40321 agtcattggt acacatttag gtgaaaaagc catcggcatt gccatttcag cgcaataatt
    40381 ccttttattc aaaaaacata ccaaaaatat tccaacatca tcttggactt tctacatgtt
    40441 actaatgagc gtgtaaaaga acgagatggt gtttttattt ctatcaatga agctcttttt
    40501 ctttgcaatc ctcacttcaa tcctctataa tgtcgcatat agtttagtaa atgagtaaac
    40561 tactaattta cttatttact aaaaataaaa ggatgaggag ttaaaataat ggaaatacca
    40621 acaaatttaa aacataaacc agtaatcgtt gtagaagact atgataaagt tgatggaaga
    40681 aatgcattaa atacggatgc aaaagggctt tcactgggcc ttgctcagtg gaatgatcgt
    40741 ggaaaagtcg atatctcagg caaggtatgg cgacatactg gagaaaaatg gtcacgacag
    40801 tcggaagaat taccaatcac acgtatttta gatttagcga tcttagctgc acaaggaagt
    40861 ttatacttcc aagatgctta tcgttatgaa aaattttatg atccagaaaa tccagtcgta
    40921 gacatcattg gattacaagg gaaccgaatg acggtagaag tagataccaa aaatccaaag
    40981 atcgatgaag acatcatttt gtattacgat acactacaaa aagacggaga actgattggg
    41041 gaacgattcc gtattttaaa acgtctttta gatgagctag gatattaata gacagagatg
    41101 atcaaaaggg gaagagaagc atggagaatt tctcactaac agaaaaccga accttttcac
    41161 ggctagaaaa gcaaatgatc tggaagaaac cgaaaagcca tcggacaagt gcagaagaat
    41221 ggcggatcgc ctccgaaatc aaagggaatt ggcaagatcc tgaaatgaaa atcagtaacg
    41281 tacttttgga aggagatgcc gggtcgggga agacacaatt agccaaagca ctatctgctg
    41341 atctgcaact tccctataca aaagtgacct gttttgcaga tatggacaaa tcagatgttt
    41401 tcggagcctt attacctgta gtagattcta ataaggaaca agaccaagaa ttactagaag
    41461 ctatttacca aacagataca cttgaagctg tactgacact gatccagaac cattacggca
    41521 ttgatccttt ttctgctaaa gaaaaattag cagagctagt tcaaaggatc gaagctgatt
    41581 atccagatgc aatccattac agctattacc cttctgaaat cgttcgagcg attgaaaaag
    41641 gatatttatt agagattcaa gagccgactg tcatccgaga tgcctctgtt cttgtggcac
    41701 ttaactcagc gctcgaacca aatgggatgt tgaatttacc gacaggaatc attcgtcgcc
    41761 atccagattg cgtcattgtg atcactacaa atcgaaatta ccaaggaaat cgcccattaa
    41821 atgaatcttt aagagatcgg atgcaacatg cggaaaaaat ggatcttcct gccttagaag
    41881 tcatggcaga acgtgcgatg gcgaaaacta tgatccaaaa acaagaactt ctcttaaaga
    41941 tggcagagat tatccgtttg ttggatgaaa ctgcaaaagc taacgccatc aaaggtgtag
    42001 caggaatgcg ttcttatttt tattgggcaa atacctataa gcaaggacaa gatttactcc
    42061 agtcgattta tccaaaagtt ttgtataaat tatccactga ttcagatgaa ttggcaattc
    42121 ttgaacaagc tttgtctgac agtggattgc tactggaact tcaggacata ttgagaaaag
    42181 aaaaatgggg tcatcctcaa tctgagcata caaaaggaag aaccattagc gccgaagaag
    42241 caaatgaacg aaacatcact gaaaatgctg aagaaattct gcgcttagat gaaaagaaat
    42301 cgttgtctgc tgaagaacca aatgagggag aagagaaaca agaagaaaca atagaaaaaa
    42361 acgagattcc tcctcaaatg caaaaagaac gcagtagcga tatcgaagga aaaaatcaaa
    42421 aagaacaaca aacaggagat gattctcaag aaatgtctgc ttctgacatg gaagcacatg
    42481 ataaggaaat caagaagcaa ctgaataaag aagcgcgaca aatcatgaag gaaacgattc
    42541 atgaaaaaga aggtctcatc gttcaccgac cagctttcca aggaaaaacg ccggaagcac
    42601 gtgagctaca catgcaagta atgccaatag tagaatcact tagccggcaa attttagagt
    42661 tactggataa tgaacaaaca gagacgtacc aaaaaggaaa atacgaaggt cagcggttca
    42721 atgcaagcaa agtagcatat ggtgatttga gaaattttga caaaaagaac ccgccacatg
    42781 agcaaccttc tttagcggta gctgtacgga tcgatgaatc tgggtcaatg atacgggatg
    42841 atcggatcga agcggcaaaa aaagcagcga ttgccattgc cgaattttct aagaaagtcg
    42901 atatcccatt gttgatttac ggagatacag cagaccgttc gtcaagagaa aagacttctt
    42961 tgttttctta taaagaattt gaagacggat ttcaatggtt aaatgaaaaa ttagtcacta
    43021 tgaaaccaag gcaaaacaat cgtgatggtg ctgcacttcg tttagcagca gaaaaattaa
    43081 acagacaatc cgcaacaacc aaactgttgc ttaatattag tgacggtcag ccaaaagcgt
    43141 tgccggatta tacaggcaaa aaagcaaaag aagatatcca gtctgttttg aaagaatatg
    43201 aacgtcaagg aatcctattt gtctccgcag ctattggcca agacaaagaa gaaatcaagt
    43261 cgatctacgg tgaaagtcgt tttgtagata ttactgactt gaatgaattt cccaagcaaa
    43321 tgattcaact gattgcccgc tatctatgat aaaataaagc tcaacgaacg cacttagcag
    43381 attcgttgag cttttcgttt ctagttaccg gtaacaagga tacttctaaa atagaatcgg
    43441 ttataatcaa gagggaccgt taaaggagtg aaacgatatg atacaagaac aaaaatggtg
    43501 gaaagaagca gtaggctatc aaatctatcc tgctagtttc aaagatagca atggcgatgg
    43561 tcaaggagac atcaatggga tccgtgaaaa acttaattat ttgaaagatc ttggtatcgg
    43621 ctttatctgg atcaatccga tctatcaatc tccatttgtc gataatggtt atgacgtaag
    43681 tgactatcaa gatatagaag agagattcgg aacgatggaa gattttgatt tattgctaaa
    43741 agaagcacat gaattaggga tcaaagtgat tatggatctt gtcatcaacc atagttcgga
    43801 tcagcatcaa tggtttgaag aatcgaaaaa atctaaagaa agcccgtatc gcgattatta
    43861 catttgggtc gacggggtag atggcaaaga accgaataat tggacatcga ttttcggcgg
    43921 ttctgcttgg gagtattctc atgaaactgg acagtattat ctgcatgttt ttgcaaaaga
    43981 acaaccagac ttaaattggg aaagcgagaa attgaaagaa gaactattca atatgatccg
    44041 atggtggttg gataaaggga tagatggatt tcgtttagat gcgatttctc atgtaaaaaa
    44101 agatgaatat tcagtaaaag ccacagagaa ccctttctca ccctttcaaa atgtctcagg
    44161 aatcgaagaa catttgaccg atttgaaaca tgtttttgaa gagtacgata tcatgactgt
    44221 cggagaagca agtggtgtca ctgcagaaga aggaccacaa tgggtaggga aagacggtta
    44281 tttcgatatg atattcgaat ttgatcatat ccatatctgg cagcaagaaa aagaagggca
    44341 attagatgtc cttaaattga aacttgcatt aagcgcttgg caaacttcat tggatggtat
    44401 cggatggaac gctttatata tggaaaacca tgatgttcct cgtgccgttt cagtgtttgg
    44461 agatactcgt cccgattttt gggctatgtc tgcaaaagca atcgctatga tgtatttctt
    44521 tttgcaaggt acgccattta tttatcaagg acaggaaatc ggaatgacga atatgccctt
    44581 tgaatcgatc gatcaagttg atgcagtaga ttcgaaaaga ctttataaaa ggctgcttgc
    44641 ggaaggtaag acaagagaag aagcattgga tatcattcgt gaaacaacga gagacaacag
    44701 caggacaccc atgcaatgga cttcggaaca atatgctggt ttttctacac atgaaccttg
    44761 gctgatcact aatccaaata ccaaaacgat caatgtagaa caacaagaat atgaaccaga
    44821 gtcggtcctg caattctata agaacatgat ccgcattaga caaaccaata aaggtctgat
    44881 atacggttct tataaagaat atcttcatga acatccacaa ctttatgtct atgaaagata
    44941 tttagaagat gaacaatatc ttattatggt aaacttaaca gaatcacttg ctgactatga
    45001 acttccaaaa gaagcagatc agtcctggac attactcttg tcaaattcct ctagcggaga
    45061 atttgaagct aaaggcatac tagcacctta tgaagctcgg ttatataaaa caaacaagta
    45121 aaacttcctc gttaaagttc attagttgga ctttgcgagg aagtttttca gattgctctg
    45181 tcaattactc atttcaataa ttcgctctag gaccaccgat atatttagga cgagagcgaa
    45241 gggctgtcac gtgagcttgt ccaagggttt tcaaacgagg tctgacaggt acttggacat
    45301 gtttgatatg cataccgatt gatgtgtcac cgatatcgat accggcttgt ccaactacgt
    45361 gttccacttc gacaggatca ttgaactggt caaaagcagc aacagaacaa gcacctccag
    45421 catgtagtgc aggaacaaca gagacaattt cgaaattttt tgcttctgcc actgttcgtt
    45481 ctactactaa tgctcggttc aaatgttcac aaccttggac agctagcgca atttctttag
    45541 gatccaacaa ctcttttaac gtacggatga tccattgacc aacttccgca ctggaatttt
    45601 ttccaatatg tcctccaacg acttcgcttg tgctgcatcc taaaacaaaa agatcacctt
    45661 ttttcaagtg tgcctcagcc aatatgtcat taactatttc agtcaattgg tcttttaatt
    45721 ctttttctga caacttcatt ttctaaaacc ttctttttca attaatattg cttccgtgct
    45781 tgaatacgtt gaagacttgc agttatagga aaggcaagtc ccattccaat cagattttgg
    45841 aagatgtttc ctggtataga agccactcca gccggccaat catataaaat ccaaccggcg
    45901 ataccatagc cgatgatcat aactaagctt cctaataaaa gccctaatcc ccacatacga
    45961 gtagaagatt tgctgaaaga accagcaaca tatccttgta acccgtggat cactaatgaa
    46021 aaaactgccc actgcggata tcctgaaatc aaatcgatca atagaccact ggaagcacca
    46081 acaactaatc cacccgttgg accataaaga aaagcagcgg tatagatccc ggcctcgcat
    46141 aatgtcacaa atccattcgt agccggtaca gggatcaaaa ttgttaatga aagggcaact
    46201 gtcaacgcaa tcagcatagc atagatcgtt aattgcttag ttttcatttc tcattcctcc
    46261 tttttgaata ccgccagacc agacacttcc ggtatgatcg ttcatcagca cgccattaga
    46321 aatacaatgg gcaacaaatt ttttactttc tgctactgct ttggtaaaat ctgcccctaa
    46381 cacaagattc gctgttattg cagaagaaaa ggcacaaccg gccccgttta ctgttgtagt
    46441 gtcgattttt ttatgagaaa atacctcata atgatcaatt gaatagagaa gatccacagc
    46501 ttcatctcca gccatccttg tgccgccttt gatcacaatg ttttttgttc ctgaagcagt
    46561 gagttcttta gcgagatgga tcatttctgt taacgaagag ggaagagctt gaccagaaag
    46621 taaagcagct tctgccaaat taggcgtaat catcgtaaca agtggaaaaa gttcttcgat
    46681 gagctgcgaa atatacaatt gattgatcac agcttcagtt tctttgaatg ccaaaacagg
    46741 gtctaaaatg attgggatat tttgttttgt ttttatgaag tctcgaacaa ccatgattgc
    46801 ttcacttgaa ttcaataacc caattttgat accatctaat gaagtcattt tatcaatcga
    46861 aactaactgt cgtttaagca attccaaaga tatagattcc agcataaatc gctcattaat
    46921 atctagtgcc cctatagaag tcaaggcgct tagtccgaat agaccaaaat tctcaaaagt
    46981 ttttaaatct gtttggattc ctccaccagc aaatggatca gaaccgccaa ttgtcaagat
    47041 tcttttcata acattttcct ccatgaataa gagtataacg aaattttcaa aaaagaaaaa
    47101 cagccaattg gcatattttt atctcatcca atttaaaaaa acaaaaagaa aagaaagacc
    47161 aaaatggatc tttctttcct taaatagtta ggacttttgt gattttaatt ctttctcgat
    47221 ttgaagccgt tgcactttca ttgtagctgt tcgcgggatt gcatcaaaat cacggatgat
    47281 agggacgttc aagcgaggaa gttcatggac ttgctcccac catcgattcc aatccatttc
    47341 tttatcagga gctaaagcaa taatcggttg tggagaatga tttttatccc ttacaatcac
    47401 tacttctgcc aaaaaatcta acgaatctaa taaaaagtct tcaatagcta atgtactatt
    47461 gatcgtttcg atcaaatcca cttgccgatc tttcaaaaat aggtggccat gcttatccat
    47521 aaaaccgtaa tctccgctat cccaccaatc gccataaaca ttttcctgga accgtgcatc
    47581 ttccttgtaa taagtcaaag cccgtccttt agacagtaat tgtatatgac catctgtgtt
    47641 ttcaggtagg acattcccaa ctgaatctgt aatccgagcg cttgtcatgt cttccagtcc
    47701 aacgcccata tctcttgcat cacttgtttt caaactctct agtgtatgag ccttaagaat
    47761 cattggtccg cattcacttt ggccatatac ttgaagaaat accgcatcct gtgccatcga
    47821 cgttcgcaaa aatgtcttca ttgtctggtt gtttatagca tcaaaagtgg agtgatagta
    47881 tcggataccc gaaaaagctt ctggatgctc cttagcagta aaacgccact gaacaaagtt
    47941 attcggatgg gtctctagtg caattggccg gtgagcttcc aacatatgaa caacttttga
    48001 actttgtgcg tttgctaaag gcatcatagg aaatcccatg gacatcaaag aagagatacc
    48061 aatattgaat ctggaatgca ctggagagat gtgaaaagcg attaatttct tttccgaaat
    48121 ttttgtgaaa actgtttttt gccatttcgt ccgccatccc atagaatgag cagaatgaca
    48181 aataagttta gggataccag ttgtaccaga agtatgggtc atataagaaa tttcattttt
    48241 gtctaaaaat gattgagaaa cagacaaagc aggttgttcc attaaataaa gaatag
//
LOCUS       DBBGSP010000018        47396 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000018 DBBGSP010000000
VERSION     DBBGSP010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.018"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="ACIZE9_001179"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="ACIZE9_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HGC6093052.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2944..3378)
                     /locus_tag="ACIZE9_001180"
     CDS             complement(2944..3378)
                     /locus_tag="ACIZE9_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093053.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..4600)
                     /locus_tag="ACIZE9_001181"
     CDS             complement(3395..4600)
                     /locus_tag="ACIZE9_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HGC6093054.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5294..5680
                     /locus_tag="ACIZE9_001182"
     CDS             5294..5680
                     /locus_tag="ACIZE9_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGC6093055.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5774..5965
                     /locus_tag="ACIZE9_001183"
     CDS             5774..5965
                     /locus_tag="ACIZE9_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093056.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6479..6811
                     /locus_tag="ACIZE9_001184"
     CDS             6479..6811
                     /locus_tag="ACIZE9_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC6093057.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            6721..6915
                     /locus_tag="ACIZE9_001185"
     CDS             6721..6915
                     /locus_tag="ACIZE9_001185"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGC6093058.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            6954..7100
                     /locus_tag="ACIZE9_001186"
     CDS             6954..7100
                     /locus_tag="ACIZE9_001186"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093059.1"
                     /translation="MMDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            7538..8878
                     /locus_tag="ACIZE9_001187"
                     /pseudo
     CDS             7538..8878
                     /locus_tag="ACIZE9_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9119..10735)
                     /locus_tag="ACIZE9_001188"
     CDS             complement(9119..10735)
                     /locus_tag="ACIZE9_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HGC6093060.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKKIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            10853..11071
                     /locus_tag="ACIZE9_001189"
     CDS             10853..11071
                     /locus_tag="ACIZE9_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093061.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11266..11727
                     /locus_tag="ACIZE9_001190"
     CDS             11266..11727
                     /locus_tag="ACIZE9_001190"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6093062.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11920..12159)
                     /locus_tag="ACIZE9_001191"
     CDS             complement(11920..12159)
                     /locus_tag="ACIZE9_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093063.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12183..13706)
                     /locus_tag="ACIZE9_001192"
     CDS             complement(12183..13706)
                     /locus_tag="ACIZE9_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HGC6093064.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(13724..13846)
                     /locus_tag="ACIZE9_001193"
     CDS             complement(13724..13846)
                     /locus_tag="ACIZE9_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HGC6093065.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(13876..14859)
                     /locus_tag="ACIZE9_001194"
     CDS             complement(13876..14859)
                     /locus_tag="ACIZE9_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HGC6093066.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="ACIZE9_001195"
     CDS             complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="ACIZE9_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGC6093067.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(15053..15430)
                     /locus_tag="ACIZE9_001196"
     CDS             complement(15053..15430)
                     /locus_tag="ACIZE9_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093068.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="ACIZE9_001197"
     CDS             complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="ACIZE9_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGC6093069.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="ACIZE9_001198"
     CDS             complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="ACIZE9_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGC6093070.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16448..18214)
                     /locus_tag="ACIZE9_001199"
     CDS             complement(16448..18214)
                     /locus_tag="ACIZE9_001199"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093071.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18174..19928)
                     /locus_tag="ACIZE9_001200"
     CDS             complement(18174..19928)
                     /locus_tag="ACIZE9_001200"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093072.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(20038..20607)
                     /locus_tag="ACIZE9_001201"
     CDS             complement(20038..20607)
                     /locus_tag="ACIZE9_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGC6093073.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20625..22040)
                     /locus_tag="ACIZE9_001202"
     CDS             complement(20625..22040)
                     /locus_tag="ACIZE9_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093074.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(22051..22719)
                     /locus_tag="ACIZE9_001203"
     CDS             complement(22051..22719)
                     /locus_tag="ACIZE9_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGC6093075.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(22849..23433)
                     /locus_tag="ACIZE9_001204"
     CDS             complement(22849..23433)
                     /locus_tag="ACIZE9_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6093076.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23764..23997)
                     /locus_tag="ACIZE9_001205"
     CDS             complement(23764..23997)
                     /locus_tag="ACIZE9_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGC6093077.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(24012..24962)
                     /locus_tag="ACIZE9_001206"
     CDS             complement(24012..24962)
                     /locus_tag="ACIZE9_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HGC6093078.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(24959..25801)
                     /locus_tag="ACIZE9_001207"
     CDS             complement(24959..25801)
                     /locus_tag="ACIZE9_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGC6093079.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(25803..26522)
                     /locus_tag="ACIZE9_001208"
     CDS             complement(25803..26522)
                     /locus_tag="ACIZE9_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGC6093080.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            27070..27372
                     /locus_tag="ACIZE9_001209"
     CDS             27070..27372
                     /locus_tag="ACIZE9_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003013637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093081.1"
                     /translation="MTIAANNDTSVRLAVNWGEVKFLCAYPKQFKNFITTILGDDFIE
                     SRVYLNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKDFMNTFKIT"
     gene            27444..28670
                     /locus_tag="ACIZE9_001210"
     CDS             27444..28670
                     /locus_tag="ACIZE9_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6093082.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(28758..29150)
                     /gene="rpsI"
                     /locus_tag="ACIZE9_001211"
     CDS             complement(28758..29150)
                     /gene="rpsI"
                     /locus_tag="ACIZE9_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGC6093083.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(29166..29594)
                     /gene="rplM"
                     /locus_tag="ACIZE9_001212"
     CDS             complement(29166..29594)
                     /gene="rplM"
                     /locus_tag="ACIZE9_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGC6093084.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(30128..30595)
                     /locus_tag="ACIZE9_001213"
     CDS             complement(30128..30595)
                     /locus_tag="ACIZE9_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGC6093085.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(30715..32253)
                     /locus_tag="ACIZE9_001214"
     CDS             complement(30715..32253)
                     /locus_tag="ACIZE9_001214"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HGC6093086.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            32333..33019
                     /locus_tag="ACIZE9_001215"
     CDS             32333..33019
                     /locus_tag="ACIZE9_001215"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGC6093087.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(33220..33747)
                     /gene="msrA"
                     /locus_tag="ACIZE9_001216"
     CDS             complement(33220..33747)
                     /gene="msrA"
                     /locus_tag="ACIZE9_001216"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HGC6093088.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(33831..34508)
                     /gene="pgmB"
                     /locus_tag="ACIZE9_001217"
     CDS             complement(33831..34508)
                     /gene="pgmB"
                     /locus_tag="ACIZE9_001217"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HGC6093089.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(34505..35635)
                     /locus_tag="ACIZE9_001218"
     CDS             complement(34505..35635)
                     /locus_tag="ACIZE9_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGC6093090.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(35635..37818)
                     /locus_tag="ACIZE9_001219"
     CDS             complement(35635..37818)
                     /locus_tag="ACIZE9_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HGC6093091.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(37815..38840)
                     /locus_tag="ACIZE9_001220"
     CDS             complement(37815..38840)
                     /locus_tag="ACIZE9_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6093092.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(38885..39712)
                     /locus_tag="ACIZE9_001221"
     CDS             complement(38885..39712)
                     /locus_tag="ACIZE9_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HGC6093093.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(39709..40776)
                     /locus_tag="ACIZE9_001222"
     CDS             complement(39709..40776)
                     /locus_tag="ACIZE9_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HGC6093094.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(40802..41638)
                     /locus_tag="ACIZE9_001223"
     CDS             complement(40802..41638)
                     /locus_tag="ACIZE9_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6093095.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(41635..42504)
                     /locus_tag="ACIZE9_001224"
     CDS             complement(41635..42504)
                     /locus_tag="ACIZE9_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6093096.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(42574..43857)
                     /locus_tag="ACIZE9_001225"
     CDS             complement(42574..43857)
                     /locus_tag="ACIZE9_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6093097.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(43871..45556)
                     /locus_tag="ACIZE9_001226"
     CDS             complement(43871..45556)
                     /locus_tag="ACIZE9_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HGC6093098.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            45831..46856
                     /locus_tag="ACIZE9_001227"
     CDS             45831..46856
                     /locus_tag="ACIZE9_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6093099.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
BASE COUNT        14662 a         9300 c         7514 g        15920 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaatg gaccaaataa gtaatatctg gttttaaaca
     4381 tgtatagaag aaacatctca ttaaaatcac cagtaaagaa atggaaatct ttagtttttt
     4441 taatattatc agttagtaac tttttataat cataaaaaaa ataagtagtt ctatctgagc
     4501 gatactcttt tataatactg aattcggaat taaaaaccac gataggtaac tttaaacaaa
     4561 catgaagaga ctttaataag acttctttat ctgaaaacac ttttgtttct ctctttcctt
     4621 tctacatcat taaatagtat tttatacgtt atctaaaata ctattcctct gtcaaaataa
     4681 gctaacttac ttcattataa aatatccact tatcgctttc atgtatattc caccgtaaaa
     4741 agtacatttt atcaccgaga actcatcatt tttcatcatg atgaatacta tttacatata
     4801 tctagttcaa agacaataat tattatgatc cgttattatc taagcactat acagataata
     4861 ggaatttttc gtttctaaat attccaattt gggaatccaa taaaaatttt cgttcaaata
     4921 cgtgtctatt cgaactcttt tctagttgtt aattatgaag ggggaagaaa taaaaaatac
     4981 aatctataca cgaataagaa tattatccaa aaggaggttt tagaaaagat ttattatacg
     5041 taaaaagctc aagacatttt cttagccata aggacatgtt tgatatttaa gaagatatat
     5101 gaattttctt ttctaagtat aaagataact atccattatc aactaaaaaa acatttttga
     5161 aaataaacat cagcagtcct atcaatgcat gtgagcttat agaagttatt cgcagcgcag
     5221 cataattgca ttagcttctt ttcgtgtttt ttgcctcttt tccctttaaa tcttaatgga
     5281 ggaggtgtgc aatatgtcag ataacgacga acgcgtaaat gcccagttga ttcgattctt
     5341 tgaaaaggtc attttgaaca ccgctaatac ttattataaa aaacaagaag aaattcaaaa
     5401 acatgaacaa cttgatcaac tcccaccata tttgtttact aaagatacta taaaatttaa
     5461 acaaccgatt aatgttttaa atgtgactct ccttgttgaa gatataaaat tagcaaaaat
     5521 ccttcctttg ttgaaagaac ctgaacaaat ttttcttatc gaaaaattta tctttgataa
     5581 aactgataaa gaaattggaa aggttctggg gattacaaga cagggtgcga caaatttaaa
     5641 acatcgactt tacaaaaaaa ttcaaaaaat gctggtttaa tatctgcata ataactaatt
     5701 ttgtatgctt ctttgctcgt tctcctcctt cccaaagaaa tagattataa gtccatggga
     5761 agaaggtaga tttatgaatt ctttaaaaga agatttcatt ttagcaaagg ctggaaatga
     5821 agaagctgtt gaggcaattc tcaaaagatt tagctctttg attcataagc aatcctggag
     5881 aactggaaaa tatgatcaag attgttatca agaatgtatg cttgcaatat atctagctat
     5941 ctcgaaattc gaaattaaag aataactcaa ctaagggagt ctgtgacata agtaaaaaga
     6001 tagtttcaaa tttcgaacaa taaatttgaa actatcttct ttataattat aaagtatcga
     6061 ttttacagcg ttctataatg attcatagaa tctaaaacga atgattttaa ttatcaacgt
     6121 tttttaattc gtttttagct taaaaataac ttttgtcaca gtctcactcc taaaattact
     6181 ttatttacgt atgaagtggg caggaggtcg aatccagaac tgggctatgg tacttcaacg
     6241 aggacttctc ctctagaatt gaaaagcatg cgatttacct tccgtaacga cggtagattt
     6301 attcaactat gtgtccaatc aaaatttgtc tgatttcaaa aatagtcaag agaattttgg
     6361 ttgttaaaaa ctcttatcta tcaacttcca cagtttagtt gacaaaccct gatactaagt
     6421 tgggctatga tacacttttc ttgactatca gttacgttac cggaaggaat gaactctatt
     6481 gagaaaaaca tatgatcgta aatttaaact aaagatttca caggatatcc ttgagaaaaa
     6541 agtaactacc aagaaaattg ctgaagaata caatatctct cgtccaacaa tttcccgatg
     6601 ggtttcagaa tatcgtcgat acgggaaaaa tgcttttgct ggacaaggaa aaagattacc
     6661 tgataaagca gatttctaca ttcttgaaca ggaaaataaa cgactaaaag aggaagacga
     6721 gtgttctacg aacacaaaga tcgatacgga tctccaggga tcactcaaaa actttacgat
     6781 gaaggaatcg aaatcaataa acgtgttgta gctgttctta tgcgtgaaat gaatttatgc
     6841 acaagaggat ttcatcgacg caaatcttct catggtagag aaaaaacaat caaagaaatg
     6901 gtaaaaaaat gttgaatcga taatttgaac agaaccaaat tgatgctgtt tgggtgatgg
     6961 atattactta cattccatgt aatgacggtc gcctctattt gtccacctat attgacttag
     7021 caactcgtat tctacgttac tatatggtag attcacacat gaaaaaagag attgtcgtcc
     7081 gtccattaca aatttattaa ggagaattgc ctacggtaat tcattccgat agaggtagcc
     7141 agcatcggtc ttttatttat caagagctgt tgaacgacca ccacatcaca cattcagtga
     7201 gccaaactgg gactcctgtt gacaatgcag taattgaagc gtttcatcga tcaatcaaat
     7261 gagaattaat cgactccaac aaatataaaa gtaaaataga gatgaaggtg ttaatccaag
     7321 attatttaga agactactac ccaaacaaaa gaatccatac aaaatttatg atgactcctt
     7381 gacaatttga agcgaagaaa ataagggatc tataatatct agtgttggtg acgccttctg
     7441 ttgccaatac tttttctttt ttctaataaa cgcaaacaga caccttaaaa tcctttagaa
     7501 taaagtcgac gaaaaccatt caaaggagtg tttcaagatg tcctattcag agtttaccaa
     7561 agagttacta gatattctag acctaaatct tatctttcat gaagatgcct ttcgcaaaga
     7621 gcgaatcaat gacgaaacat gttttgtttt tgatggcaca ttgacctatc aaccggagga
     7681 atgctttcat cgccactatc aaaatgaaca aacgatcatt aaatagggct ggaaaaaagt
     7741 atccatctta ttgaatgatg tcagtaacta caagaccatt ctgcggatta acaaacagcg
     7801 cttcaaatgt aaacactgtg gaaagacttt tttagcagaa gattcagtta gtgatcgtcg
     7861 ctgctccatt gctcgcagag tcaaacaagc cattcttgag ctattaagcg aacctctttc
     7921 tatgtctttg atcgcacgta tgaagcacat ttctccgacc actgtcattc gaatacttcg
     7981 cagccttcgg cctaaaacca tttctttgag ccagctgtta ccagaagtgg tgtgtttcga
     8041 tgaattcaaa tcagtgaaaa atgtctcggg agccatgagc tttgtcatga tggacggcaa
     8101 gacccatcaa ctgattgata ttgtggaaaa tcggcaactc aatcctttac gcgactattt
     8161 cttgcgctac cctataaaag tccgtgaaca agtgcgtcta gtggtttcag atttctatac
     8221 accctatcgc acattggtga aagagtgttt tccgaatgcc cgaatcgtcg ccgatcgctt
     8281 tcatattagc caacacattg gtcgggcttt taccaaccac cgaattcaag taatgaagac
     8341 ctttaaaaaa ggggatcgtc ggtcgaagca cttaaagaaa tactggaaac tacttcaaaa
     8401 gaatgcgtgg gaattgaaag gtcagcatcg ctactggcgt ccgtcatttc gagatcatct
     8461 gacagaagca gagatagtcg atcggctatt atcttatgat gattccttaa agcgaggcta
     8521 cgaagtctac caggattttc tttccgttat cagaagacaa gatgttcctg aattcgtcgc
     8581 gctcctaaaa gaagactaca aggagttgcc agagcactac caaccagtgt tcacgacctt
     8641 caagaaatac caaacagaaa tcaaacgagc gttgcgcgtt ccctattcca acggccctat
     8701 agaatgtttg aataaccata tcaaagtact aaaacgaatt gcctatggct atagaaactt
     8761 tcaaaactac cgagaacgaa tctttttata tcgaggaaaa tattttaaga aaactaagaa
     8821 tactacccaa ctgactaaag ccagaacaac aacacggcta gacaagatag ctgtctagcc
     8881 gtgtgagtat ctcgattatt ctattgaatt tcttcaccaa cactcattga cgaagagcca
     8941 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
     9001 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
     9061 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
     9121 agtaaatgta gtaatctgtg ctttcttttt tctcaatact aataactaac ttatggggta
     9181 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
     9241 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
     9301 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
     9361 tttccttgcc atcaattcga acgatggcat atttgatagc atcttcagtt gtttcattct
     9421 ccttttctat agagaataca aataagggaa taaaagaggt aataatcaaa atgccaataa
     9481 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
     9541 taaacatatt agactttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
     9601 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
     9661 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
     9721 cgggattttt ttgtataatc atttgacact caattttagg taaactagct acccaataat
     9781 ttaatgattc aatactttta tagctacccg atgtttcaaa gatcgtcgaa aaatcactat
     9841 gttgggcaaa ccaaagaaac ccttttgctc ttgtaatatt gccaggaaaa tttttatccg
     9901 taagatgggc aaatttttgt gcgtcaagga gtaaccgatt tcgatagata aaacttgaga
     9961 taccatattc ttctgtttca ggaatatgat tttgatagcc aagctctaac tctttgaacc
    10021 agcccactga ataggaagtc tcatctatat taaaaagatt tgtatttaga attttcgata
    10081 agtctacttc acctttaatt gtcctaatta ttttggcatt ggactgtaac ttagcaatta
    10141 gaccgttaat tttgtaaatc gtcttggttg acactaagtc actattattt aaaagtaata
    10201 tgttacaaca ctcgaattga tcaattaaca agccacgaat atcctgttct tcttcaacta
    10261 cattaccttc agcttttctt tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac
    10321 gttttacatc cactactata ataatggcac caatctctaa tcgttgggtc aaatcaatgt
    10381 ctaaagggtt tttagctaat ataattgctt gaataattgg aattggtttg ctgattcctg
    10441 aagcttcaat aacaatttga ttcaagtcag aaaattgcac taattgatct agttcaacaa
    10501 tcaaatcttc gcgtaatgta caacaaatgc atccattcgg catcgaaaca agtttttctc
    10561 cagttctttt aaaacctttc ttgtcgacta ataccccatc aacatttact tcccctatgt
    10621 catttacaat gacagcaatt ttctttccgt gatcaccgta cagaatatga tttagaagta
    10681 tcgtttttcc tgaaccaaga tagccagtta agattgtaat aggtattttt ttcataggga
    10741 acctctttct ataccttgaa tttacacttt aagtgcaaca cataaaaatg agtcataatc
    10801 gatatccaac tagtataagt ttgtcgagaa cactcctaga aggaaaataa ttatgagcca
    10861 gtatcgtcat cttactatac tcgaacgaga aagaatcttt ctgcttcacg aagaaggatt
    10921 ttctattagt ataattggca acgacattca gcatagcccg tttactattt tacatgaact
    10981 gagaagaaac aagaaaaaaa ctattcacct tccaaagcgg aaaaaaatta tgcttatcga
    11041 agaaaaaaat gcggacgtta tcacattcta aatgatccgt gagtttggtc aattgttcgt
    11101 catttatttg tcgattttca gtggtcgcca gaggaaatct cgaatcgttt gaagcatgaa
    11161 catatggact tttcaattag ttttatcacg atctaacgtg caatttgcaa tgatcttttc
    11221 gatacagaac ccctctcaca cggcaataaa ggcctgatcc gttcattgca ccatcgagga
    11281 aaaacaagac atacaaaaaa tcatgtcgag tctcgtggaa agatttgcct tactcattcg
    11341 atccatggcc gtccaaaatc cgcagatgat agaagtgatt ttggtcattg gaaagccgat
    11401 attgtagctg gcaaaactgg tggtacttgt ttagtgactt tgacagacag aaaatcatgc
    11461 ttccttttag caggaaagaa ggtccccaga aagaaagccg cttatgtgag cgagaaaatg
    11521 attgaacttt taagcagtat tccaaatgag gcggtcaaaa cgatcactcc agatagagga
    11581 aaagaattct ccaatcattt cgcagttaca gaagcattga ataatatgcc cttttatttt
    11641 ccagatcctc atgcccttgg caacaatgaa caaattaaaa tacgaataga ctcattcgag
    11701 aatacttgcc aaaatcgaaa gagatagcta cggtagataa ctcaacgata aatcagatga
    11761 ttgaaaaact gaataacaga cctagaaagt gtttagattg gagaacacct tatgaagtct
    11821 tctttgataa agtgttgcgc ttgatttgac aattcaagac ataataaaaa gcagatcaaa
    11881 tccaaataag ggaaaaatga tctactctgg tattatcaat taattggcca agctattatg
    11941 ccgttttgct aaacgtctac ttcttccagt attgaccttg ataaaacaac aatcaggatc
    12001 ccgttttaat actctatgaa ctgtgtcaat actaacatgt aaagttgcag caatatcagc
    12061 taatgtactc ccatttaatc tcatttgctt tgcaaatcga taacgccgat aagcatcaat
    12121 attcttggaa tccatagaca ataatacttt tcttaccatg tatttcctcc aaaaattgaa
    12181 ttttaatgag ccatcatttc ttgagcaatt tcatgtttag acaatgaagc tggatagaaa
    12241 gtaggccaat tatgcaattc attatagagt ttttcttgac tttctccacc aaagaaaata
    12301 tggaaatgct ctgccttact tggtgcaatt ccatgatcac taaattgaat atatttaaaa
    12361 cgaccagcac ctgcatcatc agtttcaaaa ttaaaacgaa caccacggtt tcctttttca
    12421 taattcaaaa ttttgtatcc aacatatttg tatgtgtatt gatgatgttc accgttgact
    12481 acaaaatcaa tggtgttgtc tttaatgttg atagtatcaa tatctgtctt atagccagta
    12541 gtataataat ctttgtactc ggcagctgtc atgtctttat tgatttttgc tttgtaatcg
    12601 aaaacttcat ccaaaattcc atcttttaac aacggataaa cagattgcca ttcgcctgta
    12661 taatcactca attcgcgatc cttcacatcg gcatctttaa agtacccatt agcaactgtc
    12721 ttttcatcct tcgcttcttt ttctggaact acctcttcac cagcaaccat agttgttttt
    12781 tctaacgctt ttagattgtc ttccattact gaaacataat cttcaccatt atccatttgt
    12841 tcttttgtaa gactttcaag aggattcagt acttccaatt ttatcccagc ttcgttggcc
    12901 aaagtttttg caattttatc attagcattc ttttcaaagt aaatataatt gatcttattt
    12961 tttttaacat actcttttaa ttcagctaat cgaccagaag atggctcttc ttcaggactt
    13021 agtccagcaa taggaacttg tttcaatcca taatccaaag ctaaatatcc aaaggctgcg
    13081 tgttgcgtca caaaactttt ttgtttcgct tctttaagac tagtggtata gtcagcatcc
    13141 aaccgtttca gtttagtcaa atacttttca gcatttgtct caaatacttt tgcttttttc
    13201 ggatacaatt taactaactg atccttgata tttgaaactt ccttaattgc cattttgggt
    13261 gaaacccacg tatgaggatc tagttcatga tggtgatctt cttctccgtg atcatgatct
    13321 tcttcttcac tacctggcaa taaaatcatg tcttttgttc cttctactac attaggccca
    13381 gctttcttcc aactttcttt agcttttggt acccatgatt ccatgttttc gttatgatat
    13441 acaaaaacat cagcatcatg agcttttgcc atatccttag ctgagggctc atagtcatga
    13501 ggttctgatc ccgctggaac cattaaatcc acgttcgctt catcgccgac gatgtttttg
    13561 gtgaaatcat acattggata gaatgttgtt acaatttcta attttccatc tttatcattc
    13621 gatacttttg catcattagt gctggagcaa gctcccaata atcctagagc tgctatccca
    13681 ataagtccta cactgatttt cttcattctt tttccttcct taattatgct aatttcttca
    13741 ttttatttcg tttatgttct ttgataattt ttaatgccct ttttctagtt ttaatattcg
    13801 ggcttttaag tcgtcgatat gcactagata tatccgtttt ctccattaga aattaccccc
    13861 aatcactact tatcattatt tgctttccgc cagtaattta tcaaaactct gtttgatcct
    13921 ttcttcatcc aacatttttc cgattagaat aatagtggtt tggtcttttt gtcgagtggt
    13981 gtattgaaaa ttaacctgtt cgtttacctc ttgcatggca actataaaat cctgctcttg
    14041 taaagcaatc aatcctttaa aacgatacag gctcccttgg ttggttaaaa tcagccagtc
    14101 aatccattgg agtaaaaaat ctttttttat gtcttgatct gaagttaaga gaattgattt
    14161 aaactcatgt acttgatggt gttgatgata gtatttgcca ttatagtgat tttctgatga
    14221 atcactttca aaaactaagg gatgattaaa ttttttcaaa ttataaaaat cctttttttg
    14281 aatcgtttca ctatgtgtga acattcgaat atcggataaa gggttaatac ttttgatttc
    14341 tctctgtaat ttttttagtg cagataaatt caagttttgt tttctagaca caaaaatgcg
    14401 atctgccatg acaagttgct taagggcttg tggttctctt tcaataagtt caaaactgtc
    14461 actatcaata acagtcaata aactatcgat atatactctt cctcttagtt gaggcgctgt
    14521 taaaagtgtt tgaatgattg gttggggatc tgctatacct gtagtttcaa tgatgatttg
    14581 tgaaattggt tgttgatgtt cttctattgt ttccagtaaa gaaatcaata ttgctaataa
    14641 atcactgcga agactgcaac acatacatcc attatttagt tgtaacaccc gttcctcgct
    14701 atgaactaat aatttgtgat caatcccaac ttcaccaaac tcattttcaa ttataataat
    14761 ttcttccctg gggtagggtg agacttgcaa ggcttgattg attagcgttg tttttccagc
    14821 ccctaaaaac ccagaaacga ttgtaactgg tatgcccatt ttgtcacctt tttaccactt
    14881 agctatttca cttctttaaa aattgcccgt ctgcgcaatt ttggcgaata cttttttaat
    14941 tctaaccgtt cagggttatt ccgtttattt ttgctggtga gatacagacg ttctccagtt
    15001 tcgacacatt ccaaaataat attttgacgc ataaatcttc ctccttcaat acttatcgat
    15061 cttcaagata tgcttgaatt tgttgtgcat cttcaaaagt taactcgcca gattccaatt
    15121 gtgaaactaa attttctttc atatcaacag gtatctccca ataaccatcg atacattgaa
    15181 ataactcctc gtcatactct tcaaaaattg gatagattct taaaaaatca tcaaatgata
    15241 agccttggtc ctcatagtaa tctttgacta atccattttc aattgcctgt tgggtcggta
    15301 aacccgtttc agtaataatt cctctctcta ccatcgaacg ataaaaagtg catttatcta
    15361 gcgattgctg ggtcgtttca agataatact ttaatccttc ttcaactaaa ggtgggtaaa
    15421 taatttccat tttgattccc tcctaaaagt tatatattaa actattttga agctccttta
    15481 attactttct ttccattata gtaccctttt aaagatacat gatggctacg tctataatca
    15541 ccattcgctt cgtcaaatga aatttctggt tttactacag tttgatgagt tcttcttaac
    15601 cgtttcttcg ccttagatgt ttttcttgct ggtactgcca tgatatttcc tccttttacc
    15661 aacttgcttt ttttactcca ggaatcaacc cttgatgggc aagttctcta aacttaatac
    15721 gggacatacc gaactttcgc atataccctc ttggacgacc atccgtctga tcacgaagcc
    15781 tcagacgatt cggatttgaa tctcttggca atttagcgag agcggtgcga tctcctgcgg
    15841 cttttaattc ctgacgttta tctgcatact tttcaatcat cgccatttgt ttctttgctt
    15901 tagcaatttt cgactttttt gccatatacc tttatactcc ttttattttg atttagacac
    15961 ctcaaatcgt aatcgttacg ttttgacact gatactttac caacaagagt tgctcttgtc
    16021 aacaataaat aacatgaaat aaaactcata tgaatagata actatttgaa aacgaattta
    16081 tcggtacata gagataatca aatcatttaa aagaatatgc agtttaggct ctgaaaaata
    16141 agaattcact tttattagtc caatcaaaca caaataccgt tttaagtagc ttttcctcta
    16201 cttaaaacgg caatatgaaa gaaactataa ctttttattc aatcttttat gtttaactgg
    16261 tttatcgcca attttttaaa actttgatta ttccttatat tataagaata gacattaagt
    16321 gaactaattc aatcatactg attctttcgt gtattcaaaa ttagatgctg tttaataaaa
    16381 ttattctttt tgaaaaagaa ttataactat atcccaaaaa ttgtaggtta atttaaagcc
    16441 tatttcatca tcgtgattga gcttcttttt catagacgaa tttctcagat agtttagttt
    16501 tctttatgag atttttgtat atttctgacc ttcgatacaa ctcattatga gtaccttgat
    16561 caactagttt tccttgatcc atcactacaa ttttatttac cttttcaata gacttcaagc
    16621 gatgcgatat aattagtact gtcttatctt gtattaaacg atttaaactt tcctgaatac
    16681 gtttttcatt ttccgcatct aaactggcag taatttcatc taaaattaaa attggcgcat
    16741 ttttcaaaaa agcccgtgct atggataggc gttgtcgctc tcctccagaa agtgaacttc
    16801 cgttttctcc gaccaatgta tgataaccgt caggtagttt ttcaataaag tcttcgcagt
    16861 tagctaaacg agctgctttt ttcacttcct catctgacgc ttgactattt ccaatacgta
    16921 tattttccaa aatacttgta ttaaacaaag ttacctcttg aaaaacaata gcgattttgc
    16981 taaacaaaga agctggagat acacgtttaa tatcataccc atcaattaaa atacagcctt
    17041 catcataatc atacagtcta gacactaatt tcaagatact agttttcccg gaaccactag
    17101 cacctactaa cgcagtcact tctccttgtt tagccgtaaa agagatatga tctaaaattg
    17161 gggtattgtt atcatatgag aaagagacat ctcgcaactc aatgtcaaaa gatttcagag
    17221 gactatctga tccctcttgg atactggttt ccttcatagc tctaattcgc tgtattttag
    17281 gagctaaata aaatatttca agcactgctt ctttcataga atcgaaggaa tcctttattt
    17341 ttattgcggc tagtaagtaa ccaacgacgt agagtatagt cacttcaccc gttaacagta
    17401 agtgaacacc tactagaatg actactgcta aactaacata tgagaaaata gaggataagg
    17461 ccatgactga aaaagtactt aattctacct ttaaatgaat cctttcactc tcttccattt
    17521 ttttgaaaag tctgtcttga acttttttag atagattaaa gctattaatc tcttgctgca
    17581 attctatagt ttcttgaaat tcttccgagt tctctctcaa agtatcgtaa tatttagtat
    17641 tggctttcgt ttgggatttc tttgataaca agattaagac aaaactaaat aacgttggca
    17701 aaataacagc taatcccatt ttgacattac caaccaaaag catcactgaa ataaaaggga
    17761 aaaacagagc cataccgccg gctttaggta ttgcatgact catcgcatgc tcaatacctt
    17821 caacgtcaga catgatagtt tgagataaat ctgataaatt atgttttgaa aaataggata
    17881 atggtaaatt tgacaaatcg tctgcaattt gcactcttaa atgcgcactt tctttataag
    17941 tactattata taagttttca tactccctat ctaacaacca atacatgaaa agcaaagtaa
    18001 caaacgatac ggcaaaataa agccaacggg gctttgtatt ttctaaaact aattcgtcta
    18061 tcagcatcat tataatgaat gctggtacca tattaatgca gtatacaaaa aaactagaaa
    18121 tagaagcttt agttaaagct tctgcgccct gatcacttaa agcaaatttg tttttataaa
    18181 aacttttcat tgtcaagcct ccaatcattt gcattctcat aattagtgac caattgttta
    18241 tacacttgat gtttagccat taattcatta tgatttccac gttctactat tttcccttct
    18301 gacaagacaa gaatttcatc tacagattta atgctggata atcgatgagc tatcataata
    18361 actgtttttt ctttcatcag atgttgaaaa gccttttgta gttcatactc attatctgga
    18421 tcaatagatg cactggcttc atccataata acaatctttg catcttttaa aattgctctg
    18481 gcaatagcta tacgttgttt ttctcctcct gacagataaa ctcctttact accaattaag
    18541 gtatgctctc tttcgggaaa tttttctaaa atcgattcgc aaccggctaa tcttagcgcg
    18601 tcaaatactt tacttgctgg cgcttgagga tttgctatag aaacgttatc gtaaatactc
    18661 tgattgaata gtttcgtatc ttgaaagaca aaagcaattg tgttaataat tgtgtctttt
    18721 gaatagtgat ttaaaggctt accaccaatt ttaatctgtc ccttatccac attgtagaaa
    18781 cctgaaatta gtttagctat cgtactcttt ccgcttcctg attttcctac taatgcataa
    18841 attctttttt gttctaaaac taagttgaaa ttttctaaaa cacactcttc tttgtatgaa
    18901 aagctgacat tttcaaatgc aatgtcacaa tttttaatct gtgtctcgtt cccatatttt
    18961 agttggtctt gcttcatttc taaataaagg gagtctagtg tttcgactgc atatcttgct
    19021 tcaaacaagt gcatacttac atacattatt ctcatgaaag aaacaaaaat aattccactt
    19081 aaaaaaaaca acatcaacaa gtcaacagct aatatcttgg gagtggtaag agaagttata
    19141 aaaaaggtta taggaactat caaaatgcaa actatgccaa aaaatagcca ttgaaaaaga
    19201 acaaaaggtg ttttcccact caaagaatac ttatatgcaa acttagcata atcgttaatt
    19261 gctttattca aggctttaaa tgatgttact ttagcaccaa atatctttat aacttgaatt
    19321 ccgcggatat attctaccgt ttcagagctt aacacatcta acgattcttg atatttttga
    19381 ataaaatttg tattctctgt cattttcttt aacaagaata caccaattac taacatggcg
    19441 attagaacca atccaatttt aaagttaatg aaaaagccta aggcaactga taaaacaggt
    19501 gttactatgg cttgagcact atctggaatc aagtgagcaa ttgccatatg tgttttagcc
    19561 gcgttgtcat caattgtctt tcgaatatat cccgaagaat ttaaatcaaa aaaacgaaaa
    19621 cttgcttctg ttaaaccgct aattcccttt tttctcaaat tagtctctaa gcgaaaccca
    19681 aggatatgag aaaataagcc agaaaaaata taaaataaag ctcctaaagt taaccaagca
    19741 acagtttgaa ccgcataact cttagctaaa tattcatctc ctacaataat tagagactga
    19801 agaaatttgt aaatactgta atatccatag actgttaata cgacagaaaa atcagaaaat
    19861 aaagtggcta accatccgta gtatttcatt ttagggacat aactaaataa ttttttgtat
    19921 actttcattt tttcctcccc cgcattcaat ttcttctctt attcgtttac aactgttaat
    19981 gctttccgta atagcgtaaa ttagagatgt acaaacagat aaaaggtaaa ctacgttcta
    20041 ttttttgtat ttttttaaga cttttcttcc aatcaataca ccaatcatag ataaacttgc
    20101 tacaactaac actgaaatga ttccccatat acctaccgca tagtggatca ttgcatccat
    20161 tgttgcagca gattgtcctt tatctatcca atcttgacga aaacgatctg taaagaacca
    20221 tataggaatc cactgtccgg cagcactgcc taattgcatt agagcccaag acgcaacttg
    20281 aggaattgct cgatcatatc caaatacaga tagaataata tcagctaaga tcgccatact
    20341 aatcgaactg ataaaccaag gtaagtacgc cccgcccatt aacgtaaaaa ataacaataa
    20401 aacaattgtg taaatagtaa aaattccttt tctagggtag ttatagctaa tataaacaaa
    20461 tatgattcca gataataatc caaaaatccc gggggatatg ctgtgaccaa acgccccacc
    20521 aatactacta accattattg aaaaaaagta aattactagg gaaataactg tagctaaacc
    20581 aataaaaata taatcttttg ttttcatata tattctcctc aattctattt cgttatgtca
    20641 ttaaaaatct gttctatcaa agttgaatct tctactctaa gttttatatc tttttttatt
    20701 ccaccatttt ttaaataaat aattctattg catgttttat aaagaaattc cggatcatga
    20761 gtagctataa ctactgcacc cttttctttt aagtctttaa taaggtcagc aatcctttcc
    20821 atattaatat aatccaaccc acttgtaggt tcatcaaata gaaataaatt agtttttgac
    20881 aatgaagcta tagaaaccaa taatctttgt ttttctccac cggataaatc aaacggtaat
    20941 tgatctttca ttttataaag ttccattttt tttaaaattt tttcttgctg atctttacta
    21001 actatttcat tccccagggc taactcgctc ctcactgatt ctgtgaaaaa ttggtaatcc
    21061 atttcttgca ttactaaaaa cggcgatgac aaattttttt tattttcgat tatctttcct
    21121 ttggtagggc gaataatctt catgagtatt cttagtaagg ttgttttccc cacaccgttt
    21181 ttccctacca aaccaataac atctccaact ttgacatcaa aatttatgtc ttttagaata
    21241 ttttcataag taatttcttc aacttttaat acatctgcac ttaccttttc gatataggga
    21301 acttcaatcg aactattaaa aatgtcaaat ttccttaatg cgttattgtt ttcagttttt
    21361 aacaactgaa tagttgtagt ttttacagtt ctatttttaa caaatagaac ttgatcaatt
    21421 aattctttca aatagtaaaa acgatgttca gctataacaa tagtaaatcc tttatttttt
    21481 aaatcacaaa gtaagtcagc aagtttctta gtcgctttga agtccaaatt tgaagacggt
    21541 tcatccaata taattaattt agagtttagc gataaactac atccaataga aattttctgc
    21601 cgttcaccac ttgatagcga aaaaatgttt ttatctaata tatttgaaag atctaataat
    21661 tcagctaatt cattgattct tttatccata tgctcttttg taaatccaaa gttttccatc
    21721 gaaaatacta actcactcgt tgtatttgtt gtaaagaatt gtcctctagg atcttgactt
    21781 acgtagccaa tattttttga tatactttct tgtgttaagg attgtagcga gttattttca
    21841 aataaaattt ccccaaccaa ttttccgtca taaagtcttg gaataagtcc attcattaac
    21901 tttaatagtg tggatttccc actcccagaa gaaccagtaa tcaatgtaag actgcctttt
    21961 tttattgaaa aattaaggtc aacaagcgct tgttccttaa catccttata tgaaaaagaa
    22021 acattgttaa attcaaacaa ttctttcacc tcaaatcaaa atacttaaga aaaaaatagt
    22081 aacggaaaac aggatgatat agtctaataa gctcatgttt gttttatagt aagaacttct
    22141 tttcacagga gattctatcc cctttgttat tgcattagcg gtcatttctt cagcaatcat
    22201 agttgcacgt ataagaacgg gaactaacag aaattccaaa tattgcagag gctgaaaaaa
    22261 agacaagcga atgtttctca tttttaaaga ttctttaatc attcttattt cagaacgata
    22321 agtcggaaag aatctgatca ctactgtaat acttaacatt atttttttcg gtaaatgtat
    22381 tttttctaaa gaggataata attcattgct agtatagaca ctaaccaaca accatgagat
    22441 cattacgacc ggcaacattc gaaatacaat atataaggat gtcgcaaaaa atatagtaaa
    22501 aaactctatc ttgatagcat caataatttt cattactaaa aacagaactg aataaatcaa
    22561 gatgaaataa atacatgtct ttattttacg aaacatcaat actaaaactg tagcaataat
    22621 gaaacacccc acttgaaata tatttccctt tcctaaaaaa ataatgaccg gaaaaaaaat
    22681 atttaaagta atcaaggtta acggattgat ttttgacact ctttcacctc caaaaaataa
    22741 gatcgcactg ttatcttaag ctgataaaaa tgcaccgtta ttcagataac agtgcgatct
    22801 tatcaaaaag cataactgag aacaattctc aatgcaagct ttttttaatt aactcagtaa
    22861 ttcaatccac ccaggaacag aaaattgata caatcttctg gttaatagca tagtcttttc
    22921 ttttgaatag ctatgcttca atatatcata gaatgtagcg tagaatgagt aaatgtagaa
    22981 gtggatttct tcttcattaa agactaaatt ttgattgatc attccgatag tctttaactt
    23041 atctagacaa cagactgtct ttttcgtcac aaatgatgta attttttcaa caatatcttg
    23101 atatttggtt ccagctgatt ggaataaaat caaatcgaat atacgtttat tctcaaaaat
    23161 ataattaata aatggatcta attcattgaa gttctctctc caacttttct ctatatctat
    23221 attttctaag tttaagaggt atttggtaaa ctcttcatta tacatattaa taagcgcatt
    23281 aatatgcggc tgaataattt cttcaaataa cgcttcctta gaagtaaaat gtttataaaa
    23341 agcacccgta gttacgcctg cggtcaggca cagttgcctt atcttagttt gctgaaatcc
    23401 ttctttttca aaatggctta gtccactttc tattaacttt tggtgagtta taatataatc
    23461 tctggtttct atgggtactt cctcctaata agatgaatta actttattat cttacacagg
    23521 acttgaagtt tcaatcgtta acgtttatta ctgaactcat tccttagagc taaactaatg
    23581 agaaagagca gaataactga tacaaaaagc aatcctacaa gaattaatag actcatctaa
    23641 atcattcacc ttttctaaaa taatccgaga aagatttaaa aaaattatat ccagctatta
    23701 ggataagtcc tatcataatc actccaatag ccattttctt atcctcccta aaaataaagt
    23761 cttttactta aaaccttttt tgtaatcgtc aataaatttt ttccctttat cagttaattg
    23821 aaatcctata tctaaatagt cctcatatct aagtttagcc agcatctcac ttacagatgc
    23881 tggactaaca cttagaactt ttgctaaatc attatttttt aatttctttt ttctttttga
    23941 taattcctga attgctagta aataaattag tatagtagtc gttttaattt gtaccatacc
    24001 taccctccaa attatttcga aaggccttca gcaattttat ccaggttcca tttcatcatc
    24061 gcatagtaac tatcaccatc ttgtcctttt tctgcaattg aatcagtaaa aatcgttgaa
    24121 tagataggaa tattggtatc ttttgatact gttttcattg gtctatcatc cacactgctt
    24181 tctacgaata aggagggaac ttttgttgtg cgtaattttt caactaagtg ttttatttga
    24241 tctggtgttc cttcttcttc agtgttgatt tcccaaatgt aagcagaagg cacattatac
    24301 gctttcgaga aatatttaaa gcatccttca cttgtaacaa tcattttttt atcattcgga
    24361 attgaagcaa atttagattt agcttctttg tctagagaat ccaatttttc aatatactta
    24421 tctagatttt ctttatagaa ttttttatta tcaggatctt tttccgctaa ctgtttttca
    24481 atatttttag cgtaaataat accgttttct aaatttaacc aagcatgagg atcttccttc
    24541 cctttctcac tctgaccctc taagtaaata acatctatgc catcacttgc tgcaaaatag
    24601 tctttgtttt cctctttgtt cgcattttta actaattttg taaaccaagc atttcctcca
    24661 gtttccaagt taacaccgtt ataaaaaatc aaatctgctt ttgaagtttt ttgaacatct
    24721 tcaggcaaag gttcatattc gtggggatct ttcccaatag gtacgatact gtgtaaatca
    24781 attttatctt ttgctatatt ttcggtaata tctgctaaaa tcgaattagt aactactact
    24841 tttaattttt cgttcgaagc cactttatct ttgtctttac tatttattga acatgccccg
    24901 aatataaaaa gagcaatcaa aatccccaga cttcccagta ctgctttcca ttttctcatc
    24961 ataacgatct ctccttcttt cttaaaaatt tttgttttgg tgagattaga aaactaatta
    25021 caaataagaa tgccgctgtt aaaacaatac ttgatcctgc tgctatgtta aaactataac
    25081 caataaacaa tccaagcaat gatgaacttg ctccgactgt tgcagaaata aatatcatag
    25141 ttttcaagct atttgcatat aaatatgctg tagctgctgg tgtaattaac attgcaacaa
    25201 ttaatatagt tcccacactt tgcatagctg ttactgctac taaagttaat agaaccatca
    25261 atagataatg ataaaaactg acattcatcc ctattgcttt tgccattaat ggatcaaaag
    25321 aagtgattaa taattcttta aaaaatagaa ctactataac caacactaaa accgaaacgc
    25381 caattgtaat ccacttatca atatcttgta cagctaaaat atttccaaat aaaatatgaa
    25441 ataaatccgt tgagctattt gcaactccta taaggataac tcctagtgct aaaaaagaac
    25501 tgaaagtaat accaattgct gtatctcctt ttattacact attgcttttt ataaaagtaa
    25561 taatgataga agctaataga ccaaatacaa tcgcaccaat aaaaaaatta atacctaaaa
    25621 tataagaaat tgctactcct ggcaaaacag catgagaaat agcatcaccc ataagagaca
    25681 ttcctcttaa aataataaaa caacctactg ttccagaaac aatccctata actacagatg
    25741 taattagagc attctgtaaa aagtgaaagt catacagacc attaataaaa ttttgaagca
    25801 tattattccc cctctccaat aaatatagta tctccatagg ctttttttaa attttcttca
    25861 ttaaatacag attctacact tccgtgagca attagatttc gattcaaaag aataatatta
    25921 tcaaaatact tctttacctt gcttaaatca tgatgcacaa ttagcactgt ttttccctga
    25981 tgtttcaatt tttttaacgt atccataatt attcgttcac taactaagtc tatccctaca
    26041 aatggttcat ctaaaaatat gaaatccgca ttttgagcaa gacatcttgc taaaagtaca
    26101 cgttgaaatt gtcctccaga taattctcct atttgatgat tagaatattt tcccatatcg
    26161 accttttcca aagcctttga aactctttgc cattctgcat ttttaattct ttgaaaaact
    26221 ttcattccgg catatgttcc catagataca cattctttta cttttattgg aaaagtaaaa
    26281 tcaatatcag ctttttgctc tacatatgca atcttcacca gttttttatt gatatcttca
    26341 ttattaatgg agacctctcc ctgatgaggg ataatattta acattgcttt aagcaatgtg
    26401 gattttccag caccatttgg accaataata cctgttaaag caccttcttg tatttttaaa
    26461 gaaatctcgt tcaatgctaa aaaatcgtta taacaaacat taagcttttt cacttctaac
    26521 ataactttct ccttctaaat gataatgatt atcacgatca tatggtatac aaaaattata
    26581 ttttagtcaa ccctaaattt tatagtttag atttttttct gttgctgaag attagaatga
    26641 caaaactatt tgaaactacg cgtatagtaa gtagctttca aaatatataa aaaaggagcg
    26701 ttctcaaatg agaacatgct cctaaaacta ctttattggc gtatggaaaa attatacttg
    26761 aagtggatag cgggttgaat aagttgataa gcatcaaaac atttataaaa attattcaag
    26821 actatgtctg ttccatatac aaatatgaaa atcagtaaac tccatttaac ttttttcgta
    26881 gtgtgtcttt ttatacatgt ttatcgttat taatagtgaa taggaaaaaa actatttttg
    26941 atcattgaca attaaataca atttttgaat aacgatccct gctattcgag ctagaaactc
    27001 aagtacgcca tgacctgatt agcgacaaat acttagagat ttctttttgt tctgggaaaa
    27061 caaaatgcca tgacaatagc agcaaataat gatacttccg taaggctcgc cgtaaactgg
    27121 ggagaggtga aattcctatg tgcttaccca aagcaattca aaaatttcat aactactatt
    27181 ttaggagatg attttataga atccagagtc tacctgaata aaaaacaaac ctgtgcattt
    27241 ctaggaatcg ataataatac tctagataag tggattcgta tatataattt cccagtaata
    27301 agagttggtg gtgtagttcg ctttgacgta gaagatatta aagactttat gaatacattt
    27361 aaaataactt gaaattttct tctcgccgca tatactaaaa ttagtgaaat atactgcctt
    27421 acttttttta aggagtgagg attttgccta caaagctttc aaatgggaaa tataaaacta
    27481 atctgagata tccaaaaagg tttaaagaaa taacaggaat tgcatcagaa aagtatcaaa
    27541 aaacatttcc aaataggcaa ttggcgatta aagccgaaaa tgatatgaag aagaaaatag
    27601 aaaaagtttt gagagaggag aatgcaaact cattagaatt aaaaggaaaa ataacgttta
    27661 aaaaatttta cgaatctaaa tggcttccta gatatgaatt aggtcaaaca attagatcaa
    27721 acaggcctcc tagtgatata accattagta atacaaaaga tatatttcgg ttgcatattt
    27781 tacctatgtt tggtgaatac gcaatgaatt atctaaatat caatactgag ataatatcag
    27841 atgaattaac caaaaaatcg aaagaatatg caaatataaa aatcataaaa ggatatgttc
    27901 gttccatgtt cgatattgca gaaatactaa attatatcga atttaatcga actactaaaa
    27961 ttattcaaag tatcactgca cctaaaaaaa atgctttaga agaaaaaaga atacaagaag
    28021 gtaagcaagc actatcatca aaagaactta ctaattggat agaagcagta aatgatgatt
    28081 ttaataatca tttacttact tttcatgatt acacactttt tatgattacc ctgtatcttg
    28141 gtgatagaaa aagtgagact tacgctttgc aatggaaata tattgatttt gaaaaacaaa
    28201 cggtccgtct taaacatact ttagataaat atcaaagaaa aaagtttaca aaaggtcgaa
    28261 aagataccgt cattcaagta ccagaagttg taatgacatt gctaagtgaa tggaaatcgg
    28321 tacaagctga tcaattgttg aaattaaaaa ttaagcaaac gttagatcag tatctcttta
    28381 cttatactaa accatctgga gaagtaaatt gtcctgttca tgccgattac ctaaactatc
    28441 gaatcaattc aattaaaaga aggcatcctg acttagttca tttatctcca cacaaactcc
    28501 gtcatactta tgcaactata gctagacaag gtggagcaga tatgaatcaa atttcaaatg
    28561 ctttaacaca ctcagatatt tctacaacaa agatatatgt gaacacacca gatatagttg
    28621 ataaggctgt ttttgaagct tttcagagag gattgaataa gtgtgattga tatgtgttct
    28681 taaatgtgtt cttaaaaaca aaagaagcac tttccaaata attgaaaagt gccagaaacg
    28741 ttgatatata aaggatatta acgttttgag aattgtgaag ctttacgtgc tttcttaaga
    28801 cctggttttt tacgttcgac catacgtgcg tcacgagtaa gtaagccagc acgtttaaga
    28861 gctaaacgga agtcaggatc aacttctagc aatgcacgag cgataccatg acggatagct
    28921 cctgattgtc cagcgtatcc tccgccgttt acgttaacaa atacgtcata tgcgcctttt
    28981 gtttcagtaa cagcgaaagg ttgattgatt acttcacgca agtcagcatg tggaatgtat
    29041 tcttcaacat cttttttatt tacagtaatt ttgccagttc ctggtactag acgtacgcga
    29101 gcaactgcgt ttttacgacg gcctgtgccg atatattgaa cttgtgccaa tgaaattccc
    29161 tcctattaga ttaagtttgt gatgtctaaa acttctggtt gttgtgctgc atgtggatgt
    29221 tctgctccac cgtatacgtt caattttgta aattgtttgc ggcctaaagt gtttttagga
    29281 agcatacctt ttacagaagt ttcgatcaaa cgacgagaat ttttagcacg caattcgcca
    29341 gcagtgattg atttcaatcc tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc
    29401 gcttttttac ctgttaattt cactttgtct gcattgatga cgatgacgaa atcgccagta
    29461 tccaaatgag gtgtgaaagt tggtttattt ttaccacgta gtacagatgc aacaactgtt
    29521 gaaagacgtc ccaatggaac atcagttgcg tctactacat accatttacg ttctacttcg
    29581 cctggtttgg ccatatatgt tgtacgcacg ttattttcct ccaatttaag ttctgatgtt
    29641 tgacatacac ttcgagtttc cggggctctt tgtggggcaa acaataccat ttaacatatt
    29701 acccgctaat ctagtcaatg tcaacgtttt tctgcttgat tgaaaaattt atatgaaact
    29761 ttacttcttt tctttctttt atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa
    29821 gaggctgtga caaaagtctt gtcacaaccc cttattttga ataaacggtg ttctcctgcc
    29881 aactcctcgg tcacaagtca caatatccat aaaacataag aagctgtttt ttaaaattgt
    29941 ttcttgtgac tcggagctga acggcaggct tacaacctct tggtaaacgg tgttcaatca
    30001 gctgaccctc ggtattagct caaaaaacgg caaaatatga ggaactattt tgacgtttgt
    30061 ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttttcggtc aagttcaaca
    30121 acagttttta cgcgtcgatc tctggcgctt tgcccaaatg agcttggatc atccagatac
    30181 gtttttctgt ggctgttttg aattcgataa agatatcttg tgttggatcg tcgccttctt
    30241 ctccagaaac ttcgattcct ttttggtaaa gatctgctag ataacgatag cctgcaacaa
    30301 gtgtttccaa acgttctgga atagtacgat cccagcggcc aatttcatca gggatttttg
    30361 tgttatctgc aaattcacgc aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt
    30421 cggatacttc atctaactga gcgttcaaat catccatgaa ctcatccatc attgggtgca
    30481 atgtaaggaa acctggtcct ctcatgtacc aatgtgtttg gtgaacaaca acagacattt
    30541 ggcttagatc tgcaactaat tgatttaata cttctttggt ttgttggaat ttcatctttc
    30601 ttgcctccta acattttctt acacttaaaa taatagtaga ctttcaatga aaagtacaac
    30661 aaaatcattt acctgagaac gattttcagt tcgctttttt atccgtaaag ccaatcattt
    30721 ttcagaatca gctaattctt ctcgcagttg agcaaattgc tgataagtct gtgctaaatg
    30781 cttttgtgtc gaaacaaata atggatagat tttctgatat tttttatgat cagtttcttg
    30841 tactccaact tgctctttca attctatcaa ttcctgtgct tcactgatac tttggatctt
    30901 tccgatgctt ctccagccta aaatcacagc tcctaatgcg gatgcttctg tgacagtagg
    30961 gaaaacaagc gggtaaccca gtacatcagc catcatctga cgaaaaatcg gagattgagc
    31021 aaacccgcct gtagcacgga tctctgtgag ctgattttcc tggcaaactc cttttaaaat
    31081 ccgataaagg ttgagacaga tcccttctag aatcgccttc atcatttctt tttctgtatg
    31141 ttgccgctgt aaaccgataa aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc
    31201 accaagtaaa tagggatgaa aaatcagacc attggcaccc gctggcacaa aagcgatagc
    31261 cgaaagcagt gcatcatatg gattttctcc tttttcttta gcagattgaa cgacttcctg
    31321 taaaaatgta tgccctgccc aatcaaagat gccagcacca ttgctagtcg ctcctcccac
    31381 tacccaatgt ttctgatcca gaacataaca aaacgtctcc atttctggat ggaactgagg
    31441 ctgagtagta ataaaacgaa gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc
    31501 accaaaagca cctaacccta gattagaaag cggcccgtct gcccctccca aaacaaatga
    31561 tatatcattt ggcaaaccta gttctgctgc tgtttttgat ggtagacctg ttacttgata
    31621 ggtggaagga aagacttgcg gcaattgctc tattcgaatg ttcaagtagt caagcacttc
    31681 ttctgcccat tggaattcat ggatatcaaa atatccagtt cctgaagctg ttccgtagtc
    31741 gctgatcagt tcgccaaaca atctataaaa gatatagtct ttgataccga caaaataagc
    31801 agtttttttg aataattcag gttggctgtt ttgcagccac ttgattttgt tcaatggtgt
    31861 cattggatga atcggcgtcc cagtctgccg ataaaattct ttgccaagca cggtatattt
    31921 cagtttttct gcttcgtccg ctgctcggtt atctgcccaa gtgatcattc gagataacgg
    31981 tgttttctct tcatccaaca atatcaggcc atgcatcgca gaggagaagg agacaaattg
    32041 aatgattgtg tctgaaggca actgtttaat tacttctttt ataacggtgc agacaccttg
    32101 aaagatcaat tcctgatctt gttctgccat cccttgtgtt tcttggatca aagggtagcg
    32161 aaaataagcg gatgctgctt cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt
    32221 ggttccgata tctaatccga ttgaaacgtt cattttttca cctcaaattt tatgtatgta
    32281 caaaaattta gtttaagctt gcgtatcttg gttttgaaaa gggggagatg gcgtgttact
    32341 ttattttatc attggttgct gtatcggatc atttttatgt ttaaccgccc agcggattcc
    32401 gttaggtcac tctattattt atcctagatc tcattgtgtc aaatgctgtc gttcgctttc
    32461 ttggtatgaa ttgattccga ttctctcgat catcgtccaa cgatttcgct gccgctattg
    32521 caggtgtcgg ttgcccttct actatttgtt ggcagaagcc ttatgtggtg gtctttttgc
    32581 ctggttcttt actttttctt ccgcaagaaa tttttcgacg ttcatatgga tgctttcggc
    32641 tttgctattt tcgttgatgg atttatttta cttcatggtc cattctcaca cgctattctg
    32701 ttcttgggca attttatgga ttttttggtt gcaggccggc gtcttccaat ggcaaagtgt
    32761 gctgttaacg tttatcgtag gcggtgtgtg ccttcgctat ggtcaatcct atctcggagc
    32821 tggcgatact ctgttgatgc tttcttggag tggtggcttg tctctagaag agttgcttca
    32881 gatcttgttt cttgctagtc tgtttggaat atccgttttt tctgtttact ttatctgtca
    32941 taaaaaaaag ttggaaaagc tgcctttcat tccttttttg agcagtgcgt tgctgattgt
    33001 ccttcatctt aggtattgaa aaaaggttgt gacaaacgac ttgtcacaac ctctgatata
    33061 tagtgttctc ttaccaaatc cttgtgactt ggagctaggc gacaggttca caacctctcc
    33121 actaaatggt gttcaatcag ctgaccctca gtattagctc aaaatgctgg ttttacaacc
    33181 tctgatatac ggtgttccat aagtagcttt ttcggcttct tatttcttga cgccccaatg
    33241 tcgacgaagg aaacctgcac gtccagaacc ttctcgataa agattgtaat ggagcttgtt
    33301 tttcttgtaa taatcctgat ggtaatcttc tgcaggataa aattcgcttc ttggttcgat
    33361 ttttgtcacg attggcttat cgaatcgccc gctgtcttgc aatgcttgtt ttgaacgctc
    33421 tgcaatattt cgttcttctt catcattata gtagatcact ggacgataag aatcaccgcg
    33481 atcagcgaac tgtcctaatg cgtcagtcgg atcggtttgc tgccaataga tttccaccaa
    33541 ctgatcataa gaaataactt ctggatcata ttcgatctct actgcttctg tatgccctgt
    33601 tgtgcctgtt gttacttgtt cataagttgg atttggtaca tgcccgccag tataaccgga
    33661 tgtcacagaa atgatccctg gctgctcttc aaatggtttg accatacacc aaaagcatcc
    33721 gcctgcgaaa actgcttttt ttgtcatata aaatccccct tttttctcat cataccttga
    33781 tttccaaaag gaggataacg ttttgcttgt gacagaaaaa acggaaacta ttatatacgt
    33841 gatacggctt ctgataaatg ccaaaacgaa cgtacttgat caaaaacggt taaatcagga
    33901 atcacatatt cagcagaagg aagatttatg ttttcaccta ttcccaatac atgcatgtta
    33961 ccagccaaag ctgcttgaca accagcttct gaatcttcaa tgaccaagca tgcatttggc
    34021 ggtacattca attgctgtgc tcctttgaga aaaacttctg gatcaggttt tgcttttgat
    34081 acttgcgtgc cgtcaataag gacatcaaaa taacttgtca aattcgtttt ttctaaaatg
    34141 aggcgtgcat ttttgcttgc tgatcccaat ccgatcttga tgtttgtttt tttcaagtac
    34201 tcaagaacag ctattgcacc aggcaaaacg gatgtttcat ccattttttg aatcgcttga
    34261 agatatagat tgtttttttg ctcagcaaag gctgatttct ctttttctga gaatttctgt
    34321 tccatttttc caaatgacag caatcgctct agtgactcgg ttctggatat tcctttcagt
    34381 tgctcgtttt ctttctcagt gaatggaatg gacagctggt tagctaaaac cagccacgct
    34441 tcgtaatgat aacgagctgt gtctacaaga acgccatcta aatcgaatag tgctgctttg
    34501 attttcatcg attacctcct tgaaaatgaa cgacttgaag taaagatgcg atgtttttag
    34561 ctgtgcgatg aagattatca gtggcttgct gtaaagcttc ttgtaaaggc acagctgcag
    34621 gaaggatcgg aaaaacggcc gaaatgccaa catctgctgc tttttcgctt cctttaccaa
    34681 cacttccgca aatagctatc acaggaacgc cctctggtac tcttctagca atcccaactg
    34741 gcgcttttcc ttttagactt tgtccatcta gacgtccttc gcctacgatt acgaggtctg
    34801 cttgctgtac ccgtttatcg aactccagta aatccaatac gtagtcgatg ccagagacta
    34861 ttttccctga agcaaatgct aacagtcctg cacccattcc accaccagca ctactgcccg
    34921 atgcctcgat tacttgaggg gcaaatctca tataaaaatc atgcatggct tggtcagcca
    34981 ctgctaattc attttctttc aagccttttt gtggtccgaa aacaaaagaa gcgccttctt
    35041 ttccgcataa aagattagta acatcagtaa tgacagtgat tttggcttta atcagctcaa
    35101 taggcacgtt cgttttatca actgtagcaa ttttacctag attttctccc agtgcttcta
    35161 ctttttgatt atcttgatcg taaaaagcat aacctagacc ttctgccatg ccgatgccgc
    35221 catcgttggt actacttccg ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca
    35281 attgtcgtat cagttctcct actcctcgcg tggataacct aagtggctgt tgttggttta
    35341 gtgggacatc tttcaatccg acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg
    35401 aagcgtactg gatttctttg tttttgccaa atgcattagt aacgactgct gtttgccgct
    35461 tcaaccttaa actgtctgct aatgatgaaa ccgttccttc tcctccatcg cctataggta
    35521 gcagatcata ttcagcctga acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg
    35581 cctctaaggc tgtcagactt tctttgaaag aatctggcgc aatcagaata cgcattattt
    35641 tcccctccgt tccaagatca gttctttttc cagctggtat tggtctccat tgacaaaaat
    35701 aggtaatgtt tctttcgtct ctttttttat tactatttgt ttttttgtca aaacaaatag
    35761 caacctgtga tttttccaaa taaaaggaaa agaaattttt tcccatgctg aaggaagtct
    35821 tggagaaata gaaagagttc cattcgttac tgtaatacct gaaaaaccaa atataactgc
    35881 tagccatagt gctcctaatg aagcagcatg aattccgtca tctgatgaat gcggatctgg
    35941 tcctaaatca atcaggcacg cttcttggaa taaatgatac gcccattcca tttcttggat
    36001 acggcaagcc tctatggcgt gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt
    36061 ttcatagtaa tgcaaattct tagaaacgat tggttgagaa aaatactcag gtaataagta
    36121 taacagcatg acaagatctg cttgcttgct gacttggagt tcatttactt cgctacgggc
    36181 ataatcaagt aaaatagact ggctgccagg acgttctttg taagtggtca aatcaataac
    36241 tggcttactg agatacgtgt catcttgcgg aatcagctgt tctttgttag gcactggcaa
    36301 atataactta tctaaaaaat tttgacattc tttcaaaaaa agcggatcgc cagcttgata
    36361 tttaacagct aaggccacat tataatgcgc cagatagttc gtatatgcat tattgtcgat
    36421 atattctgtg tattcatctg gaccaatgac tctgtgtatc tctaaatgat catcgacttt
    36481 tacagctctg ctcagccaaa aagctgctgt ttcatgaatg agcgtttttc cctttgtttc
    36541 taaaaacgat tgatcctctg ttgcttggac atactcttga acggcataag caaggtctgc
    36601 actgatatga tgttctgcgg cagctgaagc aacttcttgt cttgttccgg ttttgatatt
    36661 caatgcagca aatttgggtg tctcttcctg accagtgtgt gcgctttccc atgggaaaag
    36721 tgcaccttga tagtgataat ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg
    36781 gtacagcagc aaattctttg ctacttcagg aaactgatat aaaaagaaag gcaggataaa
    36841 aatttccgta tcccagaaaa catgcccttt ataaccttcg ccagttagtc ccttcgcccc
    36901 tacactaaca cttggatcat tgcggggagt cataatctgt aaatggtaag cagcgaagtc
    36961 catcgctaac tgatcgaaag aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa
    37021 atctgtccaa taagacatcg actgctctaa aatttctgta taactaacgc ttttctgggc
    37081 ttgggcaata cttttcttaa acgggtctgt ttgctgaaga gaggtagaga gcacgatgat
    37141 cttctccagc gtaaaggacg tattttttct gatcttttct gaaaaggaag cggtgatccg
    37201 gcgatttttt gcttggaata cacctgcttt attgaattta gctgcaatcc caatatcaat
    37261 tttactttct gttgtctggt aggatgcact gatcaaatcg tcaccaaata ctcgcagttc
    37321 tttttcaacc aactgctgtg taccaaaatt ggtttgctgt ccatcgatac ccgttttcac
    37381 atctacttgg cagtcttcgg tcaacggctt gatgaccact ttcagggctg cctgatggag
    37441 attattttga tcagcaacac gacaagtaat gacttccact ttttttcctt gagcagtttc
    37501 aatgagcgca tagcgtttaa gctctcccat ttctaaatct agtgcccgct cgtatgcaag
    37561 aactttcatc gtctcaagag aaaaatgttc accgtcgatt tttatttccc atctgatgac
    37621 atctgggaga ttcactaact cggctgattc tgctcctaaa ggtcggttat atacaccagc
    37681 tgcaaacatt ccccttactt gattccgata gtcttcctcc tggcttcctc tgataccaaa
    37741 aaatccattt ccaatggtca tctgactcgc atacttattg atatactcta aatcaaactg
    37801 tttttcttct actttcataa ggtaataact tctcctgttt ctgccgaacg atataaattt
    37861 tccaccagat tctggatgac atatccttgc cagccatctg caatcatctg agtctggtca
    37921 ccgagcgccc gattcacaaa atgagccata cttagttcat gtgggtcatt aactggcgtg
    37981 gtcttttgta aggaaaccag ctttccatct acatcttcga atagttcgcc tggatacaga
    38041 ttagcacctg cctgatcgcc acaaaaagcc acattcagtt tgtcttctct gatattcaaa
    38101 gcaaacgaag tattcagttg gatgatcttg ccgttttcta attccagtgt gccaaaaatt
    38161 gcatcttcta ctgtgaattt gcttggatcc catttcccga atttccctga attttttttc
    38221 gtaccaattt tttggaagct gtacgcccga acgcttttta ctttaggaaa tccagtaata
    38281 tacatcgctg tatcaagcat gtgaatgcca taatcgatca aaggcccgcc tccttgaagt
    38341 tctttgtcga taaacgttcc ccagcctgga acaccagacc gacgaagcgc attcgcttct
    38401 acgtaataaa tatccccgag aacatcaaga tgattcttga tcattgttgc ttcgtcagaa
    38461 aaacgatgct ggaatccata agccaaaatc tgcccgtttt tatcggctgt ctctgccatc
    38521 tttcttgctt gatcagctgt catagctggt ggtttctcgc acatcactga agcattagct
    38581 tcgagggcag ccaatacatg ttcgaagtga aagcgattgg gtgtacagac actcacgata
    38641 tcgggagaaa tctcattcag catttgtgta actgatgtat acgcatgaga aaatcctgta
    38701 cgtcggcaaa agtcttctgc tcgctggctg actggatcaa ccacagcggc caattctaag
    38761 acatctgatc ttttttgata ataagcagca tgtacttttt ctgctacttg tccagcgcct
    38821 atgattgcta ctttcttcat ttatttctcc ctcctttgct tatttactta ttgttattct
    38881 ttctctattc tttctctaaa tcatttaaat gacgcgctgt ttccagacag tttttcaagt
    38941 attgcaatga ttcctgataa attttcactt cattttctcc tcgcaaacga cattcatata
    39001 ccatataacc ttcatactca ttttgaagta gcgtttgaaa atggcgagta aaatcaattg
    39061 cgccagatcc tggttggtag cgatgattat ctgctaaatg gatatgaccc acatactctt
    39121 tttgcgtagt caatgctttt gaaatatcat cttcttcaat attcatatga taaaaatcag
    39181 cgatgatctg cacatgtttc aattgattag agtcaatgta atgacgcgca tccgctaaca
    39241 aattgatcat atggtcttgg tatcggttca aaggctccaa ataaataacc gtacctgttt
    39301 cttcggctac tttatctaaa taacgaagtg attcgctgac tgctttatag tctccttctt
    39361 tgcttcgggg tgaaaccatc ggcggtaatc gataagtgaa cattccccaa gctgctggga
    39421 taacgattcc tttgcctcca acctcgctta gtgcacgcaa aatctcagca atttgacgta
    39481 caccattaag acgccgttct tcgataaagt caccgatcca cccatcgtag ccgttacaag
    39541 ctgtcactac tgggatccct gtttctttga ttgcctgttt gactgtgtcg atattttcta
    39601 ttaacaactt accgtcgatt tcgtattctt caaatccaca gtctttgata aatctaaatt
    39661 tttctaaaat gtctcttggg aaaaatgctt gatcttgcgt accgaatttc attgttctcc
    39721 tcctcggact tgaacgccca ttttgatact ttcttctggg tgctggtcta cataacgcat
    39781 gtaagcttct gcgctttctg caaatggcac aactggatca atgatttctt cacaatccaa
    39841 gtaaccgttc atcaataatt cccaacatgt gtcctcgatt cgtttacggt tccatcttgg
    39901 gtaatctggg tttggttcac tagatgctcg agcaaagacg atttttgcat tattgaaatg
    39961 tgcttcgcga ccaagattaa acccagctgg aaaaggttta gcaaaggcaa cataagaaat
    40021 gatcccgcca tagccgatcc ctcttaaaga agcttgtaat gcggcagcac tgccactcgt
    40081 ttcaataact gaatctactc cacgtttatc tgtcaattcc tttagacgaa aaccgacatc
    40141 tgctttcata ggatctagcg tgtaatcggc accgtatttt tctgctaatt ctctacgctg
    40201 cgctatggga tcgatcccaa cgatggtagt agcacctgct tttttagcta attgaatcgc
    40261 aatttgcccg atagcgccta aaccgaagat tgctacagca tcacctgctc gaacatgtgc
    40321 ttcccggata ccacctaaag cgaattgagc aggatcgtaa catactgcat ttttccattg
    40381 atccaaccga tcaagtttac gtagtttata attatcaaca ccgtttgtaa tcagcgtttc
    40441 acgaatgggt ccataagtgc agactaactc tcctttttga tactctgtca ccaaactgcc
    40501 cgtttcttcg atcgtaccga caatcatatt tcctaattga aattcgccaa ataccacacc
    40561 gcgttggctt ccttcttctc ttggcaagaa taggcgccat tcttctgaaa attcttcatc
    40621 gataaatgga cttaatcctc taaagtcgac aatttctgtt cctggttttg gagtagcgaa
    40681 aattactcgg atacgtactt cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc
    40741 ggctattctt ggttctaatg caactaattt tttcatcttt tctttcctct ttcttttctt
    40801 tttatccttt tacgccgcct tcgactaaat cacctttaat aaatcgttca gataacgcat
    40861 acataatgat gactggtaaa gcggtcacca atgaagcggc catcattcgt ccccaaatgt
    40921 agtctggtgt actgaataat gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg
    40981 acaggaaaat cgaagcaaat aaataatcat tccacgaaac cataaagcaa taaacgaaga
    41041 cagaaatgat tccagaaata gccaatggta taatgatccg aataatgatc tggatccggc
    41101 taagaccatc gatcattgct gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt
    41161 ttagcatgaa tatcgcagta ggaagtgttt gaacgaccat cgtgataatc agtgctgtat
    41221 tggtatcata caaacctaga ccggaaatga ttttaaataa tggaacaacg atcaaaatac
    41281 cggaaaacat ataaacggtg taaaagctag cattgatttt cgagcgagct ttgaagcgta
    41341 gttttgacaa agcgtatgcc ccgctgatcc caatcactac tgcagttacg gaggctatca
    41401 aggagatcac taaactattt ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa
    41461 tatcctgata atgttcaaaa gtccattctt tcggaaaaat agtttgtgtc gttgcaattg
    41521 cttcttgtga atccttgaat gatgtcatca gcatgatcaa aaatggaaac aaattgacag
    41581 ctaatagcaa caaaatcgtc gcgtaaaata agattttcct gctcttttta tttttcattt
    41641 caagtccacc ttctttcgtg agagcaagac gaccgctgca ataatgatga acaatagaat
    41701 cgatatagct gctgcttttc caagatcatt gaacgcaaag gctgtctgat acaaataaac
    41761 gcctaagata ttgactttat tcgtcagtag atagacatct gtaaacatat agaacatcca
    41821 gatagatcgt aaaacaatca cagttgctag tactggtttg attgccggca gtgtcacgat
    41881 cttgaacttc tgccaagcat ttgcaccgtc catttcagct gcttcataaa gcgttttgtc
    41941 gactgtttgc aaaatagcca aaaatgaaat aaacgcatac ggatagtatc tccagatagc
    42001 aaacaaaacg accataaaga agctagcaac tggctggtcg aaccacagcg gtgcttcgtt
    42061 gaaaagctgc aacctatcta ctaacagatc attgacgatt ccataactat tattgaacat
    42121 atatttccaa gcaaaaatca aagaaataga tggcgtaaca taacttaata aaatcagtga
    42181 acgcaccgtt ttcctaaatc tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa
    42241 agctgtactg cctgctacaa ctaagaatgt gtaagcaact gttaaaccta aagaacgata
    42301 aaattcacta tcacttaaaa tttcaagata attgcttaat ccgataaaaa cggcgtctga
    42361 gttaggattc agcggcatat cgaaaaaact gatctgaata ttggaaagca ttggaatcag
    42421 cactaaaaca gctaataaaa gcatgcttgg tgctaaaagt cccatggcta attttaagtc
    42481 agaatgtttc cttggacgat tcattgaaac ctccccctga taatctgcca atagctatct
    42541 acttttttcg aacaccattg gcagaacttc ttgttatttc gtattttttt gtgcgtcagc
    42601 taaagcttga tcgacatctt cgtttccgac agttacttgg ttcactgctt ttccgatcac
    42661 acctgagctt gtgatatctc ccattttcgt gaaattcttt tccccgacta gtccaaagac
    42721 ttgtacttca tcaaaagcac tagcaatctc agatggcagc tcgccaaaag acttgatgac
    42781 ttcattttct ttgtaaccat ccagttcgac tacttgttta ttcactggtt gagcaccacc
    42841 aggagacatc aagacccact tttccatgtt tttcggttga gataagaaag ctgtgaatgc
    42901 ttcagcagcc tctttttgtt tctcgtctag accagaagaa atcgtcaatc cagatactgt
    42961 gccatagaca gcttgatctt tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc
    43021 cgcttcataa acagaaggca aaatgtaagt tgaatagatt gccattggtg ctgttccatt
    43081 catgaaagca tctttgattt ctgtcacatc attagagcct ggcatcgtgt attgggataa
    43141 gttttgataa aacgacaatg cttctctcat cttttccgta tcgatcgtta cctcgccttc
    43201 atcatccaaa acatttgctc catttgacaa agcaaattga gagaacgctt gctcactcat
    43261 tgttccttca gcagtaggca tagcaattcc atattgttta ttctctttat ctgtgaaatg
    43321 ttgagcaatt tttaaaatat catcccaatt ttctggttct gaaaaaccag cttctgataa
    43381 tttttctttg tcataccaaa taccttgaac ccagccgcta attggtgcag caatatagct
    43441 ttttccatct tctgaacgaa caaggttttt ggctccgtca taataattat cttctccagc
    43501 ttcctcgata acgttttgga ctgccgtctg atcaatcagt tcatctttat ccatcacttt
    43561 agcaaaatcc tgactgactt ccattacttc tggtaattta ccggaacgag ctaacgtaac
    43621 gatttttgta ttgaacgctg attcttctac cggcacttgc ttgattttga tgtctggatt
    43681 ttctttttca aaatcagcaa ccagttcatt gatcacactt aatcgttcct gttcgacaga
    43741 agagtgcatg aattgaatcg ttgtctgttg tgattcgtta gagctttgac tttcaccaca
    43801 agcagtaaga agaaatccag tagctagcag acaggtagta acaataattt ttttcatttt
    43861 tttccacctc ttattttatt attttcagcc acatatattc atacggctgg aatatcaact
    43921 ttcgttcttg actgcaatgg ataatttgtc cagaaaacag gtctaggtaa tctccttttg
    43981 gtaaaagata acctgctgat tgattggaaa aattatggat aactaagact ttctcttcct
    44041 tcgcttcgcg aataaaactg ataaaagaat ctgctgagtc cagtaagtaa atcaaactat
    44101 tcggatggaa ggctttttct ttttttcgaa tagatagcat ctgggtcaat tcaccatata
    44161 ctgctgttct taatggatct gtctgcaact ctttctcaat atctgctaac aaaaattttt
    44221 gccgattgat ttttcgattc tctcctgttt tttctacgcc tttgtaatca tttcgacttc
    44281 ccagcacact ttgaatataa attgccggca cgcctggtaa cgttaccaaa aatgaatgag
    44341 cagctaaaaa gcgtttgctt ctccattccg tcgtatctgt tggagaactt aacgcatcta
    44401 gatacgtagc gtttatctca tatggactgg tcgttccatc tgggtttttc ttgtagttta
    44461 ctcgggtacc ctctttcttc agctgttcca ctaattcaag gatcgttttt tccggcagaa
    44521 tacctcgtac cggattcaat ccgataccgt catgggaggc taaaaaatta aaaaaagttg
    44581 tttttttcga tgcgaaatcg atggttttta accattcttt caacttactt gtattacccg
    44641 aacgaatcgc ttgaagggtc aaaggtggta gcgaaaactg atagaccatc tgtgcttcat
    44701 tctcgccatt cccaaaataa ctgatattat ctttgtgtgg cacatttgtc tcagtgatca
    44761 ataccgttcc tggagctgct tcatcagcga ttgcacggaa taattggatg attttatgcg
    44821 tttctggcag gtgtatacaa gaagttccta gttctttcca taaaaatccc acagcgtcca
    44881 agcgaataaa tgaagcgcct ttttctaagt aaaacaaaag aatatcgatc attttcaata
    44941 aaacttctgg atttttaaaa ttcaagtcta cttgatcttc gctaaaagtc gtccatacgt
    45001 gtttttcttt cccgtttttg tcaatgaacg ttgtaagtaa cgggctggtc cttggtctag
    45061 tcacgctgct tgtatctgta tccagtggca aatcaataaa aaaatctttg tacgtatcat
    45121 tcaagtttaa atattcctga aaccaagtac tttcggcaga catatgattg cagacaaagt
    45181 cgaacattaa ccgtgtttcg cttctcattt cttctatatc ttcccatgtg cccaaacggt
    45241 cgttgattgc ctgataattt acaacggaga aaccatcatc agatgtatat gggaaaaatg
    45301 gcaagaaatg tacaactcta aatgtatctg ccaaatactt ttgataaaat ttcttaaatg
    45361 tacgcaaagt tggttgctgc tcttcaaaaa attgatcccc ataagtaatc aagaaaatat
    45421 cttcttcgtc ccaatgcagt ttgcctgcct ggcctttctt ctgctgataa acactgactt
    45481 tttgttcaat catagaggcg gttttctcag acaaatctga gtcgcgataa atcgcttgta
    45541 aaagttttgt atacatcgga ttcccctttc ttttttggga gcgttcccaa cgatttgatc
    45601 atattatgga aaacgcttac tgtcaatagc atttttttaa ataattttga tatacacaaa
    45661 aatacaaata agaaagctta tgtatcaata attaatagct tcttaaaaaa atatggtctc
    45721 tcatgatcat gcaagctatt cctaaatttt caaaatcata gacaaaaaag aatgtctatt
    45781 gtactatgga attattctaa aacgctccca aaaaggaggt gcatataaaa ttgaaaccta
    45841 ctatttatga cattgcgaaa aaagctaatg tctcaaaatc aactgtctcc agagtattaa
    45901 ataaccagcc aaatatctct gataaagcaa aagcaagtgt acttcaagca atcaaagaat
    45961 tgaattatga accgagcaaa attgcaagag gactgtcagg aaatggtttt gacgcgattc
    46021 tagcattatc tcatcgtact tctcatacga cctatggcaa tccttttttt tcagatgtta
    46081 ttcaatccat ttctgccgtt tctgaacaaa ataacttcga cttgattcta caaacggcaa
    46141 aaacaccaga agaagagcta gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag
    46201 gaattattat tttaagctct acgatggatg aaacacttct ttttgaattg gatcaataca
    46261 atattcctat tgtggtaatc ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg
    46321 acacggataa tttccaggat agttacgatt tggtggaaac actgatcaag aatggacacc
    46381 gtcatatcgg ctgtctccat gctccgacag aagtttatgt atccaatgat cgtctcaatg
    46441 gttaccgtca atgcttattt gatcaccacc tagatatccg taatgaatgg attatagacg
    46501 gcggctttcg cttagaagat agcatggcag caatgaatga tttaatgaag ctacgagaaa
    46561 gaccaactgc gattttttct accgatgcat taaaatcatt gagtatttac aaagtggcag
    46621 aacaatctgg aaagcagata cctgatgatc tttcgatcgc aggattcagt gatcccttat
    46681 tgtcctccct attttcgcca cagttgactc ggatagacat tccgacaaat cagttaggaa
    46741 tcaaagccac agaactttta ttccaactaa tccaccacca ataccctgaa gaaaaaagaa
    46801 tcattctttc aaccgagatt actctcacag attcgatcca acaacaagaa atgtagaaca
    46861 gaattataaa agaacagaaa cactgaggat aagtcagtta ctctgttctt ttttcaatca
    46921 ctcatccctc gttaccccct cccggtattt tagcgaattt ttcttatttt ccatctgttt
    46981 tagatagctg tggataacta taatgtttgt gttaaactat tttttccaca gggaagaaaa
    47041 aactattttt aaccacgttg tgtataagtt tttatagttc gtttttttaa acacatttac
    47101 ccttatttca atccatgtta tttggggata cttatctcta aaacataaat agaataacag
    47161 acatgtctac tggttttgtt ttattcgagg aattattcaa taatagctag caaaatatta
    47221 aaaataaccg ctctatcttc ccatcaattt attttgcatt caaaaaatga tctatcttta
    47281 cttttgttga ttgacttctc ttggaagatg atcgttccga taccttaatt ggatacgaac
    47341 cgatgttgtt aagatccttt cccacttttc ttctagttag acaaattatt ttagac
//
LOCUS       DBBGSP010000019        47373 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000019 DBBGSP010000000
VERSION     DBBGSP010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.019"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(28..1260)
                     /locus_tag="ACIZE9_001228"
     CDS             complement(28..1260)
                     /locus_tag="ACIZE9_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGC6093100.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1515..2084
                     /locus_tag="ACIZE9_001229"
     CDS             1515..2084
                     /locus_tag="ACIZE9_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6093101.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2262..2702)
                     /locus_tag="ACIZE9_001230"
     CDS             complement(2262..2702)
                     /locus_tag="ACIZE9_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGC6093102.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2860..3624
                     /gene="map"
                     /locus_tag="ACIZE9_001231"
     CDS             2860..3624
                     /gene="map"
                     /locus_tag="ACIZE9_001231"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HGC6093103.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3656..4579
                     /locus_tag="ACIZE9_001232"
     CDS             3656..4579
                     /locus_tag="ACIZE9_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGC6093104.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4804..5043)
                     /locus_tag="ACIZE9_001233"
     CDS             complement(4804..5043)
                     /locus_tag="ACIZE9_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093105.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5048..5467)
                     /locus_tag="ACIZE9_001234"
     CDS             complement(5048..5467)
                     /locus_tag="ACIZE9_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HGC6093106.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5694..6932)
                     /gene="mef(H)"
                     /locus_tag="ACIZE9_001235"
                     /gene_synonym="mefH"
     CDS             complement(5694..6932)
                     /gene="mef(H)"
                     /locus_tag="ACIZE9_001235"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HGC6093107.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7039..7674)
                     /locus_tag="ACIZE9_001236"
     CDS             complement(7039..7674)
                     /locus_tag="ACIZE9_001236"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6093108.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(7788..7880)
                     /locus_tag="ACIZE9_001237"
                     /pseudo
     CDS             complement(7788..7880)
                     /locus_tag="ACIZE9_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(8016..8651)
                     /locus_tag="ACIZE9_001238"
     CDS             complement(8016..8651)
                     /locus_tag="ACIZE9_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6093109.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9163..10305
                     /locus_tag="ACIZE9_001239"
     CDS             9163..10305
                     /locus_tag="ACIZE9_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC6093110.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10298..10504
                     /locus_tag="ACIZE9_001240"
     CDS             10298..10504
                     /locus_tag="ACIZE9_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HGC6093111.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10583..11776
                     /locus_tag="ACIZE9_001241"
     CDS             10583..11776
                     /locus_tag="ACIZE9_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6093112.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11981..13120
                     /locus_tag="ACIZE9_001242"
     CDS             11981..13120
                     /locus_tag="ACIZE9_001242"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HGC6093113.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13113..13913
                     /locus_tag="ACIZE9_001243"
     CDS             13113..13913
                     /locus_tag="ACIZE9_001243"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC6093114.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13913..14740
                     /locus_tag="ACIZE9_001244"
     CDS             13913..14740
                     /locus_tag="ACIZE9_001244"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC6093115.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14745..15452
                     /locus_tag="ACIZE9_001245"
     CDS             14745..15452
                     /locus_tag="ACIZE9_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC6093116.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            15552..16418
                     /gene="rfbA"
                     /locus_tag="ACIZE9_001246"
     CDS             15552..16418
                     /gene="rfbA"
                     /locus_tag="ACIZE9_001246"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HGC6093117.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16432..17004
                     /gene="rfbC"
                     /locus_tag="ACIZE9_001247"
     CDS             16432..17004
                     /gene="rfbC"
                     /locus_tag="ACIZE9_001247"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HGC6093118.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17026..18054
                     /gene="rfbB"
                     /locus_tag="ACIZE9_001248"
     CDS             17026..18054
                     /gene="rfbB"
                     /locus_tag="ACIZE9_001248"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HGC6093119.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18152..19003
                     /gene="rfbD"
                     /locus_tag="ACIZE9_001249"
     CDS             18152..19003
                     /gene="rfbD"
                     /locus_tag="ACIZE9_001249"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HGC6093120.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19037..21070
                     /locus_tag="ACIZE9_001250"
     CDS             19037..21070
                     /locus_tag="ACIZE9_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093121.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21114..22394
                     /locus_tag="ACIZE9_001251"
     CDS             21114..22394
                     /locus_tag="ACIZE9_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HGC6093122.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22604..23410
                     /locus_tag="ACIZE9_001252"
     CDS             22604..23410
                     /locus_tag="ACIZE9_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6093123.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23422..24642
                     /locus_tag="ACIZE9_001253"
     CDS             23422..24642
                     /locus_tag="ACIZE9_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093124.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24632..26218
                     /locus_tag="ACIZE9_001254"
     CDS             24632..26218
                     /locus_tag="ACIZE9_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6093125.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26257..28395
                     /locus_tag="ACIZE9_001255"
     CDS             26257..28395
                     /locus_tag="ACIZE9_001255"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC6093126.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28763..29746)
                     /locus_tag="ACIZE9_001256"
     CDS             complement(28763..29746)
                     /locus_tag="ACIZE9_001256"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGC6093127.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30124..31515
                     /locus_tag="ACIZE9_001257"
     CDS             30124..31515
                     /locus_tag="ACIZE9_001257"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGC6093128.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31531..32571
                     /locus_tag="ACIZE9_001258"
     CDS             31531..32571
                     /locus_tag="ACIZE9_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC6093129.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32590..33675
                     /locus_tag="ACIZE9_001259"
     CDS             32590..33675
                     /locus_tag="ACIZE9_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HGC6093130.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            33708..34670
                     /locus_tag="ACIZE9_001260"
     CDS             33708..34670
                     /locus_tag="ACIZE9_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HGC6093131.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            34663..36090
                     /locus_tag="ACIZE9_001261"
     CDS             34663..36090
                     /locus_tag="ACIZE9_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGC6093132.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            36092..37162
                     /locus_tag="ACIZE9_001262"
     CDS             36092..37162
                     /locus_tag="ACIZE9_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysialyltransferase family
                     glycosyltransferase"
                     /protein_id="HGC6093133.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            37149..38570
                     /locus_tag="ACIZE9_001263"
     CDS             37149..38570
                     /locus_tag="ACIZE9_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGC6093134.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            38583..39590
                     /locus_tag="ACIZE9_001264"
     CDS             38583..39590
                     /locus_tag="ACIZE9_001264"
                     /EC_number="4.2.1.115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050377 - UDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase family
                     protein"
                     /protein_id="HGC6093135.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            39602..40606
                     /gene="neuB"
                     /locus_tag="ACIZE9_001265"
     CDS             39602..40606
                     /gene="neuB"
                     /locus_tag="ACIZE9_001265"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HGC6093136.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            40603..41751
                     /gene="neuC"
                     /locus_tag="ACIZE9_001266"
     CDS             40603..41751
                     /gene="neuC"
                     /locus_tag="ACIZE9_001266"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0006047 - UDP-N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HGC6093137.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            41724..42401
                     /locus_tag="ACIZE9_001267"
     CDS             41724..42401
                     /locus_tag="ACIZE9_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HGC6093138.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            42352..43533
                     /locus_tag="ACIZE9_001268"
     CDS             42352..43533
                     /locus_tag="ACIZE9_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGC6093139.1"
                     /translation="MAIQLKLRKKELILNSRILLSSPHMGGTEEKYVAKAFKDNWIAP
                     LGENVDKFEESITKYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATV
                     NPILYQGAVPVFIDSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYER
                     ILAIANQFNVPVIEDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSD
                     KKYVEHSRFLATQARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIF
                     NRYKEAFSGIDRIEMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRA
                     LWKPLHLQPVFQGVKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIF
                     K"
     gene            43546..44523
                     /locus_tag="ACIZE9_001269"
     CDS             43546..44523
                     /locus_tag="ACIZE9_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6093140.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            44523..45431
                     /locus_tag="ACIZE9_001270"
     CDS             44523..45431
                     /locus_tag="ACIZE9_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HGC6093141.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            45432..46184
                     /locus_tag="ACIZE9_001271"
     CDS             45432..46184
                     /locus_tag="ACIZE9_001271"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HGC6093142.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            46189..47136
                     /locus_tag="ACIZE9_001272"
     CDS             46189..47136
                     /locus_tag="ACIZE9_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HGC6093143.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT        15836 a         7485 c         9104 g        14948 t
ORIGIN      
        1 attttttgca tgtgtgcgaa agtatactca agcccaatcg ccatttcgga aaatcggtac
       61 tgtagagcca tcttcacgga ttccgtcgat atccatcttg tcagatccta ccatgaaatc
      121 tacgtgggtt tgacttctat tcaatccagc ttctgctaat tcttcatcgg acatttctgt
      181 accgcctttc acactgaagg cataagcaga acctagtgct aagtgattcg atgcgttttc
      241 atcaaataat gtattgaaaa agatgatgcc agattgagaa ataggtgaag ggtcaggtac
      301 aagtgcgact tctcctaaac gacgcgcacc ttcatctgta tcaagcagtt ttgctaagac
      361 atcttctcct tgttcggcag aaaaatcaac aacttttcca tctttaaaag taaatttcat
      421 acccgagatg atggtgccag cataactcag tggctttgta cttgaaatgt aaccatctac
      481 tcgatgactg tcaggtgctg tgaacacttc ttccgtcggc atatttgcca tgaatttttc
      541 tccacgagca ttatagcttc cagcgccttc ccaaagatgg tttttaggca atccgataat
      601 gatatctgta ccgggagcag tatagtgaag ggcagaaaat tgttctcgat tcaattcttc
      661 tgcttttttt gctaattttt catcatgctt cttccatgct aagacagggt cttcttcata
      721 gacacgagtc gttttgaaaa tctgatccca taatgcctca acttgttttt cttctggcag
      781 ttctgggaag acttttgctg cccattgttt accagccgca gccacgacag tccaactgac
      841 tttatttgct tgagttgcct tgcgtaaatt cattagtgct ttgccattcg ctgattgata
      901 agacgctact cgatggctat ctacaccagc aaatgcatcg ggatcggcag aaacaacgct
      961 gatcctgctt gctccttttt caagccattc atccgcttga tcgattttag attgtggtac
     1021 attctcaata cgatccgttg cagcatgtaa aagaaattct ctttggatct ggtcgtcagt
     1081 ccattgaacg ataacctcag cggctcctag tttataagct tcttgtgtga tcaatcgagc
     1141 aaggggtgcc tgttccacgc tgatctgtaa aacaactgtg tgtccttttt ctgtggctac
     1201 gccagtttct gcaattaagc gtgcatattt ttttagaagt tcattaaaat cagataacat
     1261 aataaaaatt cctcctcacc attttttctg gtaactatta gcatgatacc atttaattat
     1321 gattcaaaca atgaggcttt aaataaaaaa aggaggttat ttttttaagg ttaagtttca
     1381 tgatatatgt tactacttgc tatttcagct tgtgaagaaa atcaaaaact aattttgcat
     1441 atcaaaaaaa acatgttaca atgaaattaa tcaatggtgg aagcgttata aaaaaattaa
     1501 ggagattaaa aaatatggca agaaaaaaga cgattactag agaacagatt ttggcagctg
     1561 cttatgaagt agctgccacc gatggattta cacgatttac tgcgagaaac atcgcgaaca
     1621 aaatgaattg ttccacgcaa ccgatttatc ttgagtttaa aaatatggat gacttgagac
     1681 aagctctttt tgagcagatc tatgatcatt tacaatatga agtgttcact gttgagcata
     1741 cagggaatac gattatcgat cttgctttta attatatcca ttttgcaaga agagagaaga
     1801 agttgtatcg ttcactgtac ttagaagaat atggtggagg aaaagagatg cagaatttct
     1861 cttatactta ctttgtgaat acagtgaaac gcgatccagc ttatgtgaat ctttcagaag
     1921 agcagatcga atctttgtat aatgggacat ggatcatagc tactgggatc gcagctttga
     1981 tgtcttcaag catcatccat ccaactgatg aacagattga aaagatgatc caagacagta
     2041 tagatgctat cttgaaattc aaagaaccaa tcgaaatcga ttgaatatac tcaaaagttc
     2101 cacaaatcag taggtaacaa gagatgtgtc aaaataagga aaagttcgtt tttcttacag
     2161 cgtatgcatt tttaactccc gaagaactct tccatgaatg caatgaataa aagagccata
     2221 cagattgaat aaatctggat ggctctttta ttgcaagtat attaaatttt tgcgactagt
     2281 tctttagcga aagcttctaa attttcgata tcttcttctt cagcattcag atccacttta
     2341 acattttcgg ctccttttga tgcgcctgtt tttgcaaaag cagcatcgaa atcatccacc
     2401 gatttgcaga attcatcgta aaaagtatca ccagatccgc agacaccgta aatttttccc
     2461 aatagatcca attcttgcaa gtcttcataa aagtctacga tctcatcagg cagatcgcca
     2521 tcatcgtatg tataagtagc tactacgcaa atatctgcct cctcgaattc atctgcatct
     2581 acttgggtac attcgttgat ttcgacttcg atatccagat tttcaaatgc ttctgcaaca
     2641 atatcggcga tttcttcagt gtttcctgtc atgctagcat atacgatttt tgctaaagcc
     2701 atgatgtgcc tcctcgttta taattattta acaattatga attataccaa aacatcattg
     2761 aaaagaaaat aaaacctaga gacacctggg gaatgtcatt tggctaaatg tatgccgcta
     2821 tgttaaaatg agagggattt gtaaaaagga gacgaaaata tgattacttt aaaatcagca
     2881 cgtgaaattg aaatgatggc agaatctgga gctttattag cagatgtaca taaaaatctg
     2941 cgtgatttta taaaaccagg aatcacaagt tgggatattg aggtatttgt cagaaactat
     3001 atcgagagtc atggcggaat tgctgcgcaa attggctttg aagggtatga atatgcgact
     3061 tgtatcagta taaatgatga aatttgtcat ggattccctc gtaaaaagcc tttgaaaaac
     3121 ggtgatttgg taaaagtcga tatgtgtatc gatttgaaag gcggcatttc tgattcttgt
     3181 tgggcctatg tagttggaga atctacacct gagatcgacc gattgatgga agtaacgaag
     3241 aaagctttgt acatcggtat tgagcaagca caagtaggga atcggattgg tgacatcggt
     3301 catgctatcc aaacttatgt agaaggcgaa aatctagcga tcgttcgtga ttttattggt
     3361 catggcgttg gtcctacgat tcatgaagaa ccagcagttc ctcattacgg agaagctgga
     3421 aaagggttgc ggttgaaaga aggcatggtt atcacgatcg aacctatggt taataccgga
     3481 acttggaaaa tgaaaatgga tcctaacggc tggactgcgt atacaagaga cggcggactt
     3541 tcttgccaat atgaacatac attggctatt actaaagatg gtccaagaat tttgacatca
     3601 caaggagaag aaggcactta ttgatctatc cagtcaatag gtacgggaga ggtacatgaa
     3661 agtttggaac aaaataaaac aaaatgaaaa tctgatgcgc tttattgaga cgactcaaaa
     3721 gcgcatcact gattcagaaa tgagtacgac ctctgtcgtc gttgcttatt atttactctt
     3781 gtctttattt ccattgatta ttgcttttgg taatatttta ccgtttctcc acatcgatca
     3841 agagactgta ctgacctatt tacgagaagt gattcctgag accgtttacc agtttatcgg
     3901 tcctgcaatc aaagaccttt tgacacaaag ttcaggaggc ttgttatccg tttctgcatt
     3961 agcggcttta tggtctgcaa gtcaaagtat caatgctttg caaattgcga tgaataaagc
     4021 gtatggcgta gaaaatagaa aaaatttttt gatcgtccgt ttcttctcac taattgtcat
     4081 tgtcttgttc atgattgcta ttagtggggt aactatcgtt cttgggttgg gacagctgat
     4141 tttggatgct attcagccaa tcgtacaaat acccgtgaac tttatcgatc agttccaaac
     4201 tttgaagtgg ccaatcacat tggtagcttt atttgtcatc atgttcttga tttatttaat
     4261 tgtccctaat gctcagttga agttgaagac gatcattccg ggcacgatct tcgctactgt
     4321 cggctggatg ctgttatcac aagtgtttag tatctatgct aggtattttg caacgaggat
     4381 cagcggttat cagatcatag gaagttttat tgtactcatg ctttggctta attttgctgc
     4441 tacgatcatc attttgggcg gaatcatcaa tgcagttgtt caagaatacg tgacgggtca
     4501 tcaaatcaaa aaacgtcgag atccaagccg aaaatggttc aataaattga aaactaaatt
     4561 ttctcataaa aaaaagtaga aacaagagtt cttattgtaa atttatatca gtaatttatt
     4621 tgaaatttta tatctaattt tcaattatcc gcataaacac tatacattca agcattttga
     4681 agtatagaaa aacactcatc ttaccacgaa tttaccacga ttgaatgagc cttgatatga
     4741 ccgtaaaact actaagggag atagcacgaa actgtgtatc tcccgatttt tttatacagt
     4801 tgattacttc actccgattt caaatttcaa tattgctttc atcatgtctg tatgaatttc
     4861 tccttttagt tcttcatcaa cctgcataat gattttacca ctttcagagt ggtaaaaagg
     4921 acgcaagcat aatttagaaa tataaccgtc ataaaacttc aaaatctctt taactgccat
     4981 ttcatctccg cttgacgctt tgcaaatcaa ttcaaaagag ggatagccat aatctttact
     5041 catttcttta cttcctttcg ctcaaaagca tttttaactt ccttagtcct ctagttcttc
     5101 tactgcaaat agcagaacgt gatacatggt acagttctga aatttctctg tcgttcattc
     5161 cttgaaaata acgtaataaa atcgcactac gctgtttttc tgacagtcta tgtaaaactg
     5221 taccaagtgt ttcatcagat acataaattg taaagtgcaa gactttaaat gatacacaat
     5281 cataaaaaca ggtatcaatc gttccacgtt caacttgttt cgtttcggct atttcacaaa
     5341 acaatacttc acgtttagaa tgtcttgcaa gctgtctgtt tcgacttttc actttgttct
     5401 taatgacaat cagcattaaa gaattgaact gtaatctgac gatatgctcg aaagaagatg
     5461 tcctcataat ctcaccccct ttctgctaat gctgaaatat ataaacggaa taccgtttat
     5521 accctttaga aatacagaaa aatggtaaga aaaaagccca cacaaaacat atatttgtgc
     5581 gagccttaaa tactgcaata ttactctttc ttttataaca ctatcctttt agcagatttc
     5641 aaattttctt ttatatattg tttttagcct aacatactat ttaacccctt gtattatatc
     5701 tctaactttt gaaaaattct ttttgaatat attgaaatca tgattgaagc aatagaagct
     5761 acaaacataa caacccatgt ttcttgtata aatacatcga ataaaatacc gtaaaccatt
     5821 tgtccaatag gttgaccgca catagcaact gctaccagcg tagccattat ctttcctact
     5881 aattgcggtg gtgtttgtgt ctgaacaaga gtgtaaattt gaacaacaaa catagtagat
     5941 acacccatag ccacaaagca catcactgta actacccagt aggaaactat tgcaggcaat
     6001 tctaaaaata gcgaaattcc cataagtaaa acagaaacag aacaaataag taacaaggta
     6061 taaaggtttt ttagttttaa ctttgaagca acaagagctg ttaaaatacc accacataaa
     6121 ccacctaatg ataatgctga ttgtgaaaaa ccatatagtg tatctggcat ttttaaaact
     6181 tcagaaatta agataggcag accaacaatt aaaacagcac ttaaaaccaa attgaaaatg
     6241 caaaccaaaa agattacgga tataaaaatg ggtttctcct ttttcaaaaa ggtataacta
     6301 tcttttaaat cgtttttagc aactgcaatt acacctactt cacgaggtct tttttggtgt
     6361 ggaatatgga taaaaatttc cataatggct gaaaaagtaa aacatataat actaacaatt
     6421 aaaatgggat tgataccata aaattgaaaa actactccgc ttatagctgg tccgataaag
     6481 tttgctaaag tatttacttg atttattata gcattaccga cggtaagttt atctgatgat
     6541 accaatagag gaatacttgc ttgtaccgct ggttgatatg caccagaaat accataaagt
     6601 aacatcaaag caacaataaa caaaggtatg ataggaattt ttcccaatga caaataaaat
     6661 actaaaatta tgattgctgt tacaaaatct agtatgacca taatgtttct tttatttgtc
     6721 ctgtcagcaa taataccacc taccagcgac aaaataacca taggtaaaaa agagcaggct
     6781 gtagcaatac caaacaaagc tgatgaacca gtttctttta acaaatagta cggtaatgca
     6841 aatcgtagga tagcgtttcc aaataaagaa attatctgtc ctataacaac aagtataaaa
     6901 tcacgattaa aaagtttttt ttctgcttgc ataaaatctc tcctttttat ttaatcaaac
     6961 agaccgtcgg tttatataat ggtttaaata aactgctctt ttatagagca gtctatcgta
     7021 tagggataac aaatacagtt atttacaaaa ctgtataaat gcagaaattg tttcttcgtc
     7081 taataatgtg tctatgccta ttccatttaa aagggcattg aatgtattgc aacgtttttc
     7141 cataccctct ttatccgtca tttcaactaa tgggttgagc catacattac ttaataccat
     7201 gataacttct gcaatttcat gtgaattttc aatctccaaa gacttatcct tgataccttg
     7261 ttctaaaacg ggttcaacaa attcaggtac tacaatttca tacatttgtt ctatttgcat
     7321 agcaagaaaa cgaggattgt ttaatagttg aggagaaact gtcaataaaa cgctttggtt
     7381 agaattgaat accgctgtct taaatatttc tcttaacttt tctaaaccgt ttaaactatc
     7441 gttatctcta attttagcaa atattactgc attttcattt ccaattcttt gaaaaattgc
     7501 ttttaaaata tcttcctttg aatcgaaatg atgataaata gcacctttag aaagttttgt
     7561 ttcattgata atatcttgca atgatgtgtt atcatatcct ttttcacaaa acatttttgt
     7621 agaaacatct aaaatgagtt ttactgtttc ttctggatat ttatttcgtg ccataactta
     7681 cctccaatac aaaccgttgg tctgattaaa gtatatctta gtattttatg cttgtcaata
     7741 taaagacttg caattttata aaaatgcaga atgcaagcct ttttcattta ttctacaatc
     7801 ttccagttgc tttccttatg cggtgtcaat tcatactgtg atacctgcgt tgcctttgcc
     7861 tgatttacca caaatcagat tttatccctt tcttcctctt gattgcccac aacagaaaag
     7921 aaaaagccct gtcaagagct ttgccaccat tggtggtgct ttgcactctt gatcgggctt
     7981 tttgtttgct gtatcttctc gcaagaggaa aaaagttact cgtcctcatc atcaaaattg
     8041 ttattcctta atacttctcg taacagttcc atatcttctt ttgagttcgg gtttatcatt
     8101 ttcacgactt gataaggtgt cttatactta tgtccctcta tgctttcccc aaacatatcc
     8161 atactgtata aatcatcata gcggtctaat aatttttgaa acttcaaatg ctggataaat
     8221 tctttgattg ggtaaaggtc ggacgcttca atgcttttcc cgttgatata gtctgtaata
     8281 tattcccgta acttttctaa ctcatattcc agccattctt cctcgctgtc aaagaagtta
     8341 tcatagtgtc catgtttcag ttctgcattt agacgttctt cggctcttaa aaactgacag
     8401 acttcctttt cagattgatt gacatacttc cattctcccg acaacaattc attgggcgta
     8461 acgtccagca cttccattat cttttccagc gtttcatagg caggatagtt caaccctctt
     8521 tcaatcttgg aaaggctctg catattgata ccgattttgt ccgcaagttc ctgttgtttc
     8581 attcccctaa attttcttat ggtctgtata ttatttccta aatggcttat tttcattgca
     8641 taaccctcca tatctcgtta tatcttcgct attataagtc tatcatgctt aatatgattt
     8701 gtaaaggcaa aaaaagatat tgacaaataa gcatataaga attactatgt tcttgtaatc
     8761 gaataagcac aatagaatga aatataaaaa cattcaaaaa gaaataccta tctgattaaa
     8821 tccgtagata tgaatatcgg ttgaaatgga acttgttaga aaaggcaaaa cagaacttgc
     8881 tgacaaagta tttctgacac ggtggcggaa gcctctcagg cttaccgcca tgacaccttg
     8941 tgtcaagggg aagaaatgct ttgtcggctg gcgagcctgc gagccttgtc tgtgcccccg
     9001 ttatctaaca ggggggcact atttcacaaa agacaagtca aaaaccatac acccccaaac
     9061 ctgtgagtag taatgagagg ttttaagaag atagtacata tcacactttt tgaaaggtgg
     9121 tttacaggta tttcaaggct attgtgggat tggaggaata caatgaacaa tttagaattt
     9181 gcacttgaaa tgaagaacaa acgtcttgcc agcggtcttt cacaaggaga acttgcaagt
     9241 cttacccatg tatcaagata tagtatcaac cgctttgaga acggaaaagc taacgccagc
     9301 aaggaaacac agaacattat cctgcgttgt ctgaattact atatctgcga taagcctttt
     9361 tatctgctcg ttgattatct gtctgtccgt tttccaacga ctgacgcatt ggaagttatc
     9421 cgaaaggtgc ttggcatgaa agcagattat tttatccatt atgactatgg gtattatggc
     9481 tataaggagc attatgctta cggggaaatc aaggtcatgg cttctgatga tgaacacatg
     9541 ggcgtatttt tagaattaaa aggggcaggc tcacgcaaca tggaatatgt cttacaggca
     9601 cagaacaggg actggtattc attcttaaac cgctgtcttg actgtggcgg tgttatccga
     9661 cgttttgact tggcaatcaa tgatatgtgc ggtctgctgg atattcctgt gctatctgaa
     9721 aaatacagaa atggtggtgc ggaatgtcgc tgtaaaaact atgaaaatgt acaaggtgga
     9781 aaattaagcg gaaaaaaccg taatttagca agtacccttt atatcggctc aaaggcaagc
     9841 acaaaatatt tctgcctgta tgaaaaacaa aaggaacagg caacgaaaaa gaaacatacc
     9901 gatattatca accgttttga aattcgtctg cgtgacaaaa aggcggtaca ggcagttgaa
     9961 gaactgttat tgacgtataa ccctcatggg ctggtgtttt atctcattac cgattttgtg
    10021 gaatttcctg actatccatt gtgggagata ttcatttccc atgacagttt accttttgaa
    10081 atgaaccctg tacctgtcaa tatggaacgc actctgcaat ggctggaaag acaggtcatg
    10141 ccgtcaatcg tgatgataga ggaaatcgac aggctgacag gttcaaacta catgaaaatg
    10201 attgatgaat gtacccacct ttctgaaaaa caggaaatgc ttgtggaaca gatgtgtacg
    10261 gacatatcag acgtaatcga aagtgagggg gtgttttatg agtaatacac aggatattcc
    10321 cgtatgggaa aaatacaccc ttaccattga agaagcgtca aagtatttcc gcattggaga
    10381 aaacaagtta agacgattgg cagaggaaaa caaggacgct ggctggctca ttatgaatgg
    10441 caaccgcata cagattaaac gccgacagtt tgaaaaggtt attgataaat tggacgcaat
    10501 ctaatgcaaa tgagccttgt atgtgttatg atgaacacaa gtcatatcaa ggctctttcc
    10561 aacaaggaaa ggagcagaca ccatgaaaga aaaaagacgg gataacaaag gtcgtatcct
    10621 gcatactgga gagagccaac gaacagacgg aaaatactta tataaatatg tagacgcatt
    10681 gggaaacaca aaatatgtgt atgcttggag attgacaccc acagacccga caccaaaggg
    10741 aaaacgggaa aaaccctcac ttcgagaact ggaacagcag ataagacggg atattgagga
    10801 cggtatcgac agcacaggca agaaaatgac gctttgccaa ctctatgcca aacagaacgc
    10861 acagaggaca aatgtgaaga aaagcacaca gaaacaacgg gaacaactca tgcggttatt
    10921 aaaagaggac aagttaggtg ctaggagcat tgatacgata aaaccctctg acgctaaaga
    10981 atgggcgtta cgcatgaaag acaaaggctt ttcctacaat accattaaca accataaacg
    11041 ctcgttaaaa gcgtcattct acatagccat acaagatgat tatgtgagga aaaacccttt
    11101 tgatttcaag ctaagtgaag tcatagaaaa tgataccaaa gagaaagtcg cattgacaga
    11161 ggaacaggag caagccttat tgtcatttat taagacggac aacgtgtatc acaagcatta
    11221 tgatgatgtg ctgatactgt taaagacagg acttcgtatc tcggaactgt gcggactgac
    11281 agtagccgac attgatttca agaatgaagt tgtgattatc gaccaccagt tactaaagag
    11341 taaggaacag ggctattata ttgaaacgcc taagacgaaa agcgggataa ggcaagtgcc
    11401 attaagcaaa gaaacgatac aggcatttca acgggttatc aacagccgac caaagataaa
    11461 gtcgatagag gtagacggac acagcggttt tgtgtttatc aatccgaaag gtaatccaaa
    11521 agttgccatt gattataacg ccttatttat ccgtatggta aagaaataca acaagcacca
    11581 caaggacaat cccttgccac atattacacc gcatacgcta cgccatacat tctgcacaag
    11641 gctggcaagc aagaacatga acccgaaaga tttacagtat atcatggggc attcaaacat
    11701 cagtatcaca atgaactggt acgctcatgc gtccatagat accgcaaaat cagaggttca
    11761 gcgtctaatc gcatagaagt atttaccacg attttaacca cgattgacag ggaaaatata
    11821 agaagataga cctagatatg cgaggtttac cacaaaagca aaatgcccgt agagccgata
    11881 aaataaggct ttgcggacat ttgagaagat ataaaaagat agtcaaaaag acatatataa
    11941 tttataataa ttatgactct taattaaagt aggtgcccat atgcttgttt cttttagtat
    12001 ggttataaga ttttttctga caattttatt atcactgata ttaacacctg tattcaaaat
    12061 catttcagta caaacaggta tggtcgacaa accaaatgaa agaagaataa ataaagttcc
    12121 aatgccttca gcgggcggac tgcctatctt tatttcattt gttatatcga ctttattctt
    12181 attccgtaaa attatccctc aatcgtatat tgtaccgatc ttgattgctt ctttagtaat
    12241 catagtcaca ggagtgctcg atgataaata tgagctgaca cctaaacaaa aaagtatagg
    12301 gatcttgatt gcttctctta ttatttattt tgtagcagat atacgtattg attccttcac
    12361 gcttcctttt attggatata tccaactagg ctggcttagt tttcccgtaa cgattttttg
    12421 gatcttcggt atcacgaatg cggtcaatct gattgacggt ttggatgggc tggcggcagg
    12481 gatttcattg atcggtttaa ttacgatagg aatcattgga tattttttcc tccatgcttc
    12541 tacagtgtat attccagttg ttattttctg tcttgtagca agtattatcg gtttttttcc
    12601 ttacaatttt tatccggcaa agatttattt aggcgataca ggagctctat tcctagggtt
    12661 tatgatggcc gtcctttcac tacaagggct gaagaacgtg acttttgttt catcgatttc
    12721 tttgctgatc gtcatgggag tgccggtaac agacacgttt tttgctatca ttaggagaaa
    12781 agcaaaccgt gtttcttttt ctacagcaga taaaaaacat cttcatcacc gactaatcag
    12841 tttaggcttt actcataaag gtgctgtcct gacgatttat gcgatggctt tgatgttttc
    12901 tttcacagct atggtcatga attatactgg aagaatcgga acgatcatat tgattattgc
    12961 catgttgttt gctgcaattt tattatttga attgattggt ctgatcaatg agaaacatca
    13021 gtttatttta aaaacattgc gatttttagg gaataaagag taccgtacgc aagtaaaaca
    13081 gaaatatttg aagaaatgga accgtcatat agatgaataa caaattaaac cagccgatcc
    13141 ttattagtat tgtgacggca aacagtgata aaatttttcg gacactagat aattttattt
    13201 caactgtaaa agatgaaaca gcagtaaaaa tccgaatttt tgacaacaat tcacttcccg
    13261 agtacaaaaa aagactaaca gagtatagga aatatcccta catcgatatc tattttcatg
    13321 atgaaaattc cggatttggt tatggacata atcacaatct gatagctagc gattctcgct
    13381 atggcattat ttgtaaccca gatattttag tggatgaaga gacagttaca gcattggtct
    13441 tgttattgaa agaacatccg gaatgtgcga tgttagcacc taagattctt aatgaagatg
    13501 gaacaactca gcacctcatc cgtgagcagc tggctgtttt tgattacgtt ttgcgctttg
    13561 tgcctttcaa atgggtcaaa aaaaagtttg acaaacgact ggctgtgttt gaatgccgag
    13621 gattgcctac tgatgctaat agttatgtac ggatgatctc aggtagtttt atggtagctg
    13681 atattgataa atttaaagag ataaaggggt ttgatgagcg tttcttcatg tactttgaag
    13741 acaacgactt gtgtttgagt tttgaaaaag caggttacaa gttattgtac acaccctttt
    13801 atgcagttat ccatttttac gggaagggtg cgcatcgaaa tgcaaaactg tttcgcgtgt
    13861 ttttgacttc tatgatgaaa tttttcaata agtgggggtg gcgttttttc tgatgaaacc
    13921 agaaatatta gtagtcgttg tgctttatca gcaactattc agtcaatctc cagcttatgg
    13981 accattaagc aaagcactta gcgaaaagca aattcagctt attatttacg ataatagtcc
    14041 tcaaaggcag caaaatgagc tgtttgaaaa agaaaatatc gtttatcatc atgatccgca
    14101 aaatcctggt ttagcggtgg cttataattt tgcgttgtct caagcagatg aaggaacacg
    14161 ttgtctcgtc actctggatc aggatacgag gctagtcgac gattattttg aactattgcg
    14221 taaagtaacc tttacagatg aatgtgttgc tgcagttccg atgatttttt ctgggagccg
    14281 acaagtttct cccctatatt cagatcgtta tatcaatcgt acagctcaag cagtagaagt
    14341 tgaaggccca acagctgaac gaatcatggc aatcaattca ggtgttgcct ggtctgtcaa
    14401 atttctaaaa aagattggcg ggtttaatcc tgctttttct ttagattttt tggatcattg
    14461 gctgttttgg aaagtggatc agttggaaaa aactgtggag atccttcctg tacgaatgga
    14521 acatgatctt tcggttttag actatgaaaa agtttcaagt aatcgatacc gttctatttt
    14581 acaagcagaa aatcgatttt atcatgaata tgatcaaagg catttatcca gtcaccgacg
    14641 acaattattg ttaagaacag ctaaacagtt cttgaccgtc aaaaaccggc atatctggcg
    14701 gatgactttg cgctcatatg ttaagaattg gaaggtgtga attcgtgcgt tcggtttgta
    14761 tagctacctt taatggaggc agatatttaa gagagcagtt agatagtatt ttatctcagc
    14821 tttcagcaga agatgaagta gtcatttctg atgatgggtc agtagatgat acatgggata
    14881 tattaactga atacgcagaa aaagataagc gaatccagct tttttcgggg cctcgtcaag
    14941 gattgatcgc taattttggt tatgcgatcc agcagacgaa aggagatcta atctttttgg
    15001 cagaccaaga tgatgtttgg ttggagacaa aagtgaaaaa gatcactgac tattttgagc
    15061 agaatccgga tcagctagta gtagtttctg atttaatcat tgtggacagc gagctgcaag
    15121 agatccatga ttcgtatttt tcgtttcgaa attccaaaga aggatggctt aataatgtga
    15181 taagaagtca ctatattggt gctggtatgg ctttccggtc ttctttaaaa cccgatattt
    15241 tgccgatccc gtcagaagtg ccgatgcatg atatgtggat tggtttgctg ggaggaaaga
    15301 agactgggtt cctaagagaa ccgttaactc tgtaccgaag acatgattta aacgcgagtg
    15361 agattgaaac acattctaaa ttacggcaaa aaatttcttg gcgtgttcat ctgattacgg
    15421 cgttgatcaa acgaaaatgg tttaaacgtt gataaaagat gtttaaatcc ttaatatttc
    15481 catgacaaat ataacaattg atgagataat aacaaagtga aatttgaaat caaaaaggag
    15541 agcagatatc catgaaggga atcattcttg ctgggggcag cggaacacgt ctgtaccctt
    15601 taacaaaggc aacatcgaaa caattgatgc cgatttatga caaaccaatg atttattatc
    15661 caatgtctac tctgatgttg gcgggaatca aagaaattct gattatttca acgccacaag
    15721 atacaccacg tttcaaggaa ttatttggaa acggaaatga tttaggactg cagatcgaat
    15781 atgcagtaca agaaagtcca gatggattgg cacaagcgtt tatcattgga gaagaattta
    15841 ttggagatga tagtgtctgc ttggtattag gggacaatat ttactatggt ggcggtctgt
    15901 ctaaaatgtt gcaacgagca gcttcaaaag atacaggcgc gacagtattt ggctatcatg
    15961 tcaatgatcc agaacgcttt ggtgtagtag aatttgatga gaatatgcaa gctttgtcga
    16021 ttgaagaaaa gcctgctcag ccaaaatcaa attacgctgt aactggcctt tatttttatg
    16081 acaatgaggt aatttctatc gctaaaggta tcaaaccttc agaacgtgga gaactagaga
    16141 ttacggatgt caataaagca tatttggata aaggaaaact atccgtagaa cttatgggac
    16201 gcggatttgc ttggcttgat acaggaacac atgaatcatt gcttgaagca tctaccttta
    16261 tcgaaacaat tgaaaaacgt cagaacttaa aagtggcttg tttggaagaa attgcttacc
    16321 gtatgggcta catcgataag gaacaattgc tggcccttgc acagccattg aaaaaaaatc
    16381 aatacggtca atatttattg aatttggccg ctgaataagg agtccttaca gatgaaagta
    16441 acagatacaa aattaacaga tgtcaaaatc gtagaaatgg acgtctttgg cgatcatcgc
    16501 ggtttcttca cagaaagtta ttcaaaagca aaatttgcag aacatggatt gaaatatgac
    16561 tttgttcaag acaaccattc actatcagct gaagctggtg tccttcgggg gcttcatttc
    16621 caaaaaggag aagctgcaca gacaaaattg attcgggtag tcactggagc agttttagat
    16681 gtagtagtgg atatccgcaa aggtagcccg acttatggtc aatgggacgg atttatctta
    16741 tctgaacata atcatcgaca gttgcttgta cctaaaggat atgcccatgg attcgttact
    16801 ttgacaccaa atgtgaactt cctttataag tgtgataatt actataatgc agaagcagat
    16861 gggggcatcg catttgatga tccagattta gcgattgatt ggccaattga tccatcaaga
    16921 gcgattatgt cggaaaaaga tcaccgtcat ccgacattaa aagaatttga agcagaaaat
    16981 ccatttgttt acggagaaat ctaagaatta aggagaaatt ttcttatgaa aaacatcatt
    17041 gttaccggag gtgccggatt catcggctct aatttcgttc attacgtggt aaacaatcat
    17101 ccagaagtgc atgtcactgt tttggataaa ctgacttatg caggaaacaa agagaacttg
    17161 gctggacttc ctagcgatcg cgtagaattg gtcgtaggag atgttgcaga tgcagaatta
    17221 gtggaccgtc tagtaaaaga agcggacgca gttgttcatt acgcggcaga atcccataac
    17281 gataattcat taaaagatcc tttcccattt gtacaaacga atatcattgg tacgtataca
    17341 cttttagaag cttgccgcaa gtatgatgta cgctatcatc acgtatctac tgacgaggtt
    17401 tacggcgatc ttccattacg tgaagacctg ccaggacatg gggaaggcga aggagaaaaa
    17461 ttcactgcgg aaacaccata taatccttca agtccatatt cttctacaaa agctggttca
    17521 gatctgttag taaaagcatg ggtgcgttct tttggcttac gtgcaaccat ttcaaactgt
    17581 tcaaacaact atggtcctta tcagcatatt gaaaaattta ttcctcgcca agtaacgaat
    17641 atcttaagcg gtattcgtcc aaaattatat ggcgaaggaa agaatgttcg tgactggatc
    17701 catacgaatg atcattcttc agcagtgtgg ctgattttga cgaaaggcag aattggcgaa
    17761 acctatctga tcggtgcaga cggtgaagaa gataataaga ccgtgatgga attgatctta
    17821 gaaatgatgg gtcaaccaaa agatgcgtac gaccatgtaa acgaccgtgc aggacacgac
    17881 ttgcgttatg caatcgattc gacaaaatta cgggaagagt taggatggaa gcctgagttt
    17941 acgaacttcc gtgatgggtt ggctgacacg atcaaatggt acgaagaaca tgaagactgg
    18001 tggaaaaaag aaaaagaggc cgttgaagca gcatatgcca aaaatggaca ataatacaga
    18061 gaaaatgtca ctgtattaat ggaaaaacac atgtgaggca ggcgctcgcc tgtctctttt
    18121 ttaaaataaa aatcaaggag cggataatca tatgttttta ttaactggag gaaatgggca
    18181 actaggtaca gaattgcgcc atttattaga tgaaaaaaat ctgcaatatg tttcaacaga
    18241 tgcaaaagac ttggatatca cagatgccga gaaaacaatg gcttacatca cagaattaaa
    18301 acctgatgtt attttccatt gtgcagctta cacagcagta gataaagcag aagaagaagc
    18361 aaaagaatta gatgagaaga tcaatgttga tggtacaaga aatgtagcac ttgcagcaaa
    18421 agctgtgaat gctcaattcg tctatatcag tacagactat gttttcgatg gaaaaaacaa
    18481 aaatgtagaa tacgaagtag acgaccaaac gaatccacta aatgaatatg gtcgtacgaa
    18541 attattaggc gaaaaagcag tagaagagat tttagaagac tattatatca tacgaacttc
    18601 ttgggttttc gggatctatg gacacaattt cgtcttcacg atgcaacgcc tagcggaaac
    18661 ccgcgacaaa ctgactgtag taaatgacca gtttgggcga ccaacttgga cacgtacttt
    18721 ggcagaattt atggtatatg tcatcgaaga aaaagcacca tttggtattt atcatttgtc
    18781 gaacgaaaat agctgttctt ggtatgaatt cgcaaaagaa atattgaaag atacagatgt
    18841 agaagttgca cctgttacgt cagaagaatt tccgcaaaaa gcaacacgtc cgcagtattc
    18901 agtcatgagc ctgaaaaaga cagaagagtt aggatttgtc ataccaactt ggcaagaagc
    18961 acttgcgcaa atgctggaag ctgccaaaaa aatgaataag taatttcctt ttatcaaata
    19021 gaatttggag catgatatgg aaaaacaaac aagaagtgca cgacgaaaag aaaagccaaa
    19081 agcgaaccag gcagattcga atttggtgct tgacctgttt ctaaaactcc gctatcttat
    19141 tggcgtttta gtcatcgtgg tcatcgttac ttttaattta aacggaagtt cacttggtgt
    19201 ttgggataaa tatgtgtcgc aaagagacga tgggaaaaaa actgatgtga tttttggaca
    19261 gaatcgggaa gtgcggtcag acgaatggct ggtgcagaca cctttttacc tctcacaagc
    19321 tgaagaggac tttccgttgg tgaacgagga ttattcatta aacggacaaa acatgatcat
    19381 tgcgtataat tctcctgtaa aggatattac ggttatcgga aaaccattca actggggatt
    19441 ctttttcctc ggaagagatc gaggactttc cttttattgg gcgatgaaat tagtcgtcat
    19501 ggtcttgctt ggattcgaag tactgatgat attaacgaag agaaaaaaag ctctatcgct
    19561 aatcggtgca tttgcgctga cattttctcc agcagtccag tggtggttca tgcaacatgt
    19621 gggcgatttg attttcttta ctttgggact gatgactgct ttttatcatt atttctacaa
    19681 tcatgataaa aaatggctac gaacgttgat gatgcttttg gtggttattt tcggtattgg
    19741 gtttatttta gtgatttacc cagcccatca agtgatgctg gcgtacttgc tgatttttta
    19801 ttttgttggc ctgcttattt actatagcaa gaaagtttca tgggatctgt tggatgtagt
    19861 gttgattgga ggggcagttt tatttattgg cggagtcatg gttcatttct ggctaacgtc
    19921 aaaagacgca ttgttagctt ctttgaatac cttatatcca ggaaaacggg taagtactgg
    19981 aggaaagtgg acgattggcg aatttttttc tttccttaca aattggaaaa ttccttttga
    20041 agatatcaac tattcgaata actctgaagt ggccctgttc tatcactttt ttccaactgt
    20101 attcctagca agtccatttg tgttatttgg caaaaaagat agcgaacaaa agttactggg
    20161 acgtattttg atgatttttt gtctgttttc tatcttttgg attaccgttg ggttgccaaa
    20221 atggctagca gaaatcactc tgctgtctta tgttcctcca ttaagagcca tccttacttt
    20281 tagttttgcg gcttgtttat tatcgatctg gtttatcgct tatatttgga gagaagatgt
    20341 tattcctatt tggtataaat tcattttgtt ggcagtaaat gcatggtctt atttctatgc
    20401 gattacgcat tcgaaaatgg ataattattt ttcggatttt gaaaccatcg cagttgctgt
    20461 gttgggaaca gtgattttag cttttgcatt atttggctgg agacgcttgt tttacctcgc
    20521 ttttgccgcc ttagttatcg tatctggctt tttcgtcaat ccagtcgtag aaggtacagg
    20581 agcgattttt gaaaaaacac tggcaaaaga aatccaaaaa atcgatcaac aagatcctgg
    20641 taaagtttgg ttgtctgaag atgaattata taacttcacc ccaacattgg gagtgaaatc
    20701 cttcaataca gtacgctttt atccagatat agctgcatgg aagaaaatcg atccgaaaga
    20761 agaatacgag aagtattata atcggtatgc tcatacaaga gcttttatcg ctaaggaaga
    20821 tacaaagttc attttagatc gtccagatat gttttcggtc acgttgaatt ttgaagacgc
    20881 agaaaaatta gggatcgact atgtgatcag taaacgacca ttaactgatt acaaccaatt
    20941 atatgaagcg cagttcacgc agctatatgg accggataaa gacggttata tgatttttaa
    21001 agtagaatat ccggattatc cagatgtacc acaaacacaa actcaggaaa atcagctagt
    21061 cgtacagtaa taggctagct gagaataatc ctgaaatgtt agtagaaagg agagtggaga
    21121 taattcaagc aatcgtacaa aaatttgtca acaaaatgag tgtcggtttc ttgcttttgt
    21181 tactgacgct agtctttttt gtttggacag cagggttagg ttttccagca actttgttta
    21241 tatataacaa tagttcatta cttatcgctt ttagtgtggc tattttgctc attttaaatg
    21301 tttataaagc aaaaggcgtc gattttcttt atctaggtgt tgcgcttgcc cttttcattt
    21361 tcttttctta ctttcgggaa ttaagaaatg agtctttatt tggagactta ctgtttcctt
    21421 tgattatttt attttgttta gtaattaaat ggatcgagtg gacaaaatgg gatcgcggta
    21481 tttatctgat tgtcttttcg gtcttcctcg gaatcacgtt atatcgtgta tttacagaga
    21541 tccaagtacc agaaggacaa agcatctggg ctccaggcaa ttcgctttct gatatttgga
    21601 tcaatacgaa tataatcgga agttctttga tgactcttgc tttattgatc agtggatttg
    21661 ccagttcttt tgaacgatgg tatgtacgaa tcatcggtgc agtagcagtt gttgcagctt
    21721 ttctcgggat ttgggtctgc caatctagag gtgcattagt cgcgttgatt gtttttgcga
    21781 tattggatct tttacctaaa tcgttgatgc gtgtcattcg tgcgccattt attgcttaca
    21841 cggttacgat tcttttagct ttgccgattt cttatctggc ggctgtctct gaaaaagtca
    21901 atttgtttac cggtcgagaa gatatttggc ataaattcta tcagacgcta ggagaaaaat
    21961 ctgaacaaat tttactagga atgaaaacat ttatcttcca acgaggaaac caatttttag
    22021 gaaaccacaa tagttataat tctattttga atatctatgg attgatagga tttgggattg
    22081 ctgctttgct gcttatcctt tttattggtc gcttaacgtt gaaagcagat ttatccaacg
    22141 ggcagatgac ttttatctgg gccttttttg cggtgatgat gcagtcattt atggaggata
    22201 cattgacttc atacccatgg gttccgatta tttatatcct gttggctatg gccgttcatc
    22261 gatatgatga accagaagtt gcggaggaat tctatgttat ggaagaggca tatgacgata
    22321 tgacttatga tgatacatct tatgaggaac aaccagatag cgctcattct tccaggatcc
    22381 aacgctatca ttgataggca caaaatacga gagaggctgt gacaaccgtc gcagcctttt
    22441 ttggtttatt gcaattgtct agcatcttct gtaaaataga aacgttagag aaaatcttgt
    22501 atcatagaaa attaagaaag aaataagaac gcagctcggt accaaaaata tggtaaaatg
    22561 gcacttgact gtaattcact gaaaatcgct tggaggaaca caaatgttta aagatttgta
    22621 tttatttatg aaggacattt atcagaacag aaaattattg ctacagtttt cgatcaatga
    22681 cttcaaatca agatatgcag gatcgttttt aggaatctta tgggcgttta tcaatccgct
    22741 atttactgta ttgatttatt ggctggtatt tggtgttgga ctgaaagcac aaatgatcga
    22801 tgcaaaatac ccatttatcg tatatttagt taccgggatg attccctggt tcttcttctc
    22861 agatgcattt gcatcaacta cggttgtttt tcgggaatat acttatttag taaagaaagt
    22921 cgtattcaat attcgtatct tgcccacgac gaaaatccta tccaatctgt acacccactt
    22981 attcttcatt ctgattggca tagctgtcgc gcttataaat ggtatatatc cttcagcaat
    23041 gtctttacag ctgatttatt atttattttg catgtgtgct ttcttgacag gattgacttg
    23101 gctgacggca tcgatccaac catttttacc tgatatcatg caattaatta cgatcgtgct
    23161 gcagttgatc atgtggacat taccgatatt atggagccct aatcagtttg attcaggtct
    23221 tgtaagcata ttgaaattaa atccgctgta ctatgttgtt caaggttatc gtgagtcatt
    23281 tttaagtgaa gcttggttct gggagcatgg aacatatact ttgtatttct gggttttcac
    23341 gttagtaatg ttcgtaatcg gctctgcagt gttccgtaga ttgaaaccac atttttcaga
    23401 tgtgctgtaa ggagaatagc tatgacagaa tatgcaatta gactaaaaga tatcacaaaa
    23461 tcttataata tgtacgcaaa accttcggat cgatttcgtg aagccctcaa tccttttaag
    23521 aaatcctatc atgatgtatt ttatgcgttg aaaaacgtga atgtagaaat aaaaaaaggt
    23581 gagatgatcg gtttcgtggg agaaaacgga tcgggaaaat ctacaatgtt gaaaatcatt
    23641 acgggagtac tgacaccaac atccggcacg atggaaatcg aaggaaaaat ctcagctttg
    23701 ctagaactag gatcaggatt caatcctgag tattctggct atgaaaatat ctatttaaat
    23761 ggaatggttc taggattttc aagagaagaa gtcgatgaaa tggtcgatga tatcattgaa
    23821 tttgctgaca tcggagacca tatttatcaa cctgtaaaaa cttattcaag cgggatgttc
    23881 gttcgtctag cttttgctgt agcaatcaat gtgaatcccg atattttgat tgtggatgaa
    23941 gcattggcag taggcgatct tgaatttcaa ctaaaatgta tggaaaaatt tacagaaatc
    24001 aagaactcgg gaaagacgat tttattcgtt tctcatgata tcagttcgat tcgtcgtttt
    24061 tgtgatcgtt cctattggtt gaaaaacgga gaagtcgtcg aatatggcga tacgatggaa
    24121 gtaacgacga attatgaaaa ctttttaaag aaaaaatcag ttaaaacagt ggatcggaat
    24181 aaaaaccaag tagaacggtt cgccgctcca gatatcgtcg acgtgacgaa agcggaattg
    24241 ttggataaag acaaaaatcc ggtggatatg ctggaacaag gagaaaaact atacgttaaa
    24301 gtaacttatg aagtaaaaga tgatacaatc aaaaatccgg ttttaggaat tgcgctacga
    24361 acagtcgaca atttttatgt atgcggactt aatactctac tagatggtat caagattcct
    24421 tggaaaaaag gagagaatat cttttatctg gagtatgaaa agttaggttt gttagctggt
    24481 gaatattatt ttgacgttgc ggtctttgaa gaaaatgcaa cggttccttt ggtatataag
    24541 acaaagtaca tgaacttgtt tgtcagcggt tcttatatcg gagaaggcat cgtggtctta
    24601 gaccataaat gggaagaagg gactcatagc aatgaaatat gattttgaaa tggacctaga
    24661 tgaacaaagc agtgtgggaa aaattgccgc acagatcaaa ccaggaagta aagttttaga
    24721 gtttggtccc ggaaacggcc gattaacgaa acatttaatc ggagcaaaac aatgtgaagt
    24781 gagcattgtt gagttagata aggaattgtt cgattttgtc agcgaatttg ctcaagatgg
    24841 attttatggt gatatcgaaa gttttgagtg ggcaaactat tatgctggac agacatttga
    24901 ttacgtcttg tttgcggatg ttttagaaca tttggtagat cctggaaaaa cattgaagaa
    24961 agtcagagaa tttttgaatg aagaaggaga gatcctgatt acattcccta acttggcgca
    25021 taattctgtc atgatcgatt tgttcaataa ccaattgccg tgggcttctt atggtctcct
    25081 agatgaaacc cataattctt tttatactca tgatggcttc caaaaagttt ttgaaaaagc
    25141 gggattattc attaatattg aagattattt gtacttagct gtaggtgata cagaattaaa
    25201 atcaacttat gaagaattgc cggaagctgt acgctatgat ttcaaaatgc gaccatttgg
    25261 tgaagtctac caatactttt tctcattgat gaaacatcca gtagcacaaa gttccattgc
    25321 agagccacaa aattctaatt atgtaaaagt gttagaagta acccagcaaa cgaaacaaga
    25381 tgaaacaatc caacaaatac cattcaataa tttcacaggg gaaaatgaga cactaagttt
    25441 ccccgtatca gaaacaacag aaagaatggt gtttcgcttc gcgcaacaac ctagctttat
    25501 cgaattcagc gcagaagctg ccggagaaaa actaacattt atcgattcga atgctgtagt
    25561 caaaacagta aatgattgtt atttgtttga tgggaaagaa ttaccagagt tcgttctaac
    25621 ggatatttct gggaaagaag tgactatcca ttgtcactat cgctttatcg gggaattgac
    25681 accaacaatg aaagaattgt tggaaacgat tcgtcccatg gctgaagtca caaagcagct
    25741 ttctgagaaa aatgacgaat tagaaagaga aaatcatcat cttcttgagg aaaatacaag
    25801 actagaccat acgttaaaaa caaccacaaa tcgctattgc acattgttgg aaagtgatga
    25861 atggacaata aaacatagac taggacgacg taagaaagaa acttcgaaaa aaatccaaga
    25921 aaaagaactt tctatatgta ttgacgagaa aatctgggat gcagaaacaa aaatattaaa
    25981 aatcatcgga tggggaatcg ctaattcgga tcgccagccc ttgtcctata agttatcagc
    26041 tgaccaatcg ccatttttcg aagcaattcc tgtttcacga gaagaagtca atcaagcaga
    26101 acagctcgca aaaggaacag aagcgggatt tgagttacga atcctttgcg agcaagaacg
    26161 ttcattctta gtggaagcag tagctcaaaa tggccaatca tggatcattg aaatgtaaat
    26221 aatgattaac ttataaagat aaggagtaaa cgaatcgtgc aaaaaaaaga aattgccgta
    26281 tttatcgatc aaatcactcg tgaacgggcc actggcgatt tgcttattgt gggctgggca
    26341 attgatgaag tgaccaaaga aatccctacg ataaaggtag aaaaagaaaa tgtgattgct
    26401 gaagcaacac atgtcgtaag attggatatc aatcatttat ataatcttga tgttaagacc
    26461 caaagcggtt ttaaggtacg tttatcaggg aaaatgagag gaaaagccat cttagacttc
    26521 caaacagcga gacatcaaaa tggcatagct gtgaaattaa acggtaaata cccttatgat
    26581 gacggcattg aatcttcatg ggaaagaaaa aaaagattac tgaaaaaagg gataaattat
    26641 gcaaggactc atggcgtaaa aaaagcgatc cgtcgggtca aattggaatt gaagccagga
    26701 tcgatcgact atgcagagtg gatcagtcgt catgagaaac cagatttgaa agagcaaagg
    26761 aaagaagcac aaggatttgc gtaccgtcca ttgatttcca tacttatgcc tgtctataac
    26821 gttgaaatca aatggctcga aaaatgcatt gattcggtac tggatcaaac gtatgatcat
    26881 tgggaactat gtatcagtga tgatgcttct actgatccag ctatccgaaa gtgtctggaa
    26941 tcctatcaag caaaagatga tagaatcaaa gtcgttttcc gaaaagaaaa tggacacatc
    27001 agtctggcaa ctaattctgc attggaaata gcagaaggag aatttatagc actcttagat
    27061 aatgatgatg aattaccgcc atttgcatta tatgaagtgg caaaagtgct aaacgtacat
    27121 ccagaactgg atgtgatcta cagtgacgaa gataaaatcg atgcagatgg caatcgcttt
    27181 gatccgcatt tcaaagcaga ctggtcgcct gatacattga tgggaaataa ttatatctct
    27241 cacttaggcg tatatcgaac aagcattgtt aaagaacttg gcggtttccg taaaggctat
    27301 gaaggttctc aagattatga tttggtcctt cgtgtgacag aacaaatccc tgcagatcat
    27361 atttaccaca ttgaccgagt cttgtatcat tggcggacga tcccaggatc aactgcaagt
    27421 aatggcgaag ccaaaagtta tatctatgat tccggagtga aagcattgac agatgccctg
    27481 tctagaagaa acatcaaagg aagcgtacgt cctggcagaa tttctggatt ttatgagatt
    27541 gcttatgacg tcttgcaaga ggatttggtc agtgtgatca ttccaacgaa gaatggctat
    27601 gaagatctaa aaacttgtgt ggattcgatc atcgaaaaaa cgtcttattc aaattatgaa
    27661 atcattattg cggataacgg aagtacagat ccaaaaatgc aagaattatt tgcagaatac
    27721 aagcatcagc tgaaagaccg ctttatcgta gaattgattg acattccatt caattattct
    27781 cgaattaaca atttagcagc agaaaaagca aacggcaaat actttttatt cttgaataac
    27841 gatacagaag tgattgagcc agattggatg acggtgatgg tttcttatgc acagtttgat
    27901 cgaatcggct gtgtaggagc aaaactgttt tatccagatg atacaacgca gcatgcagga
    27961 gtattattag gaatcggtgg tgttgcaggg catgcattga ataactatga tcgaacacat
    28021 tgtggttatt tcggccgatt ggtcattgac gtcaattact tagcagtcac tgcagcttgt
    28081 atgatggtca aggcagctga cttcaatgct gttaacgggt ttgatgaaac attagaagta
    28141 gcattcaacg atgttgactt gtgcttgaaa gtttatgaac tgggtcgtta caatgtctat
    28201 gcacatcaag cagaattgta ccatttcgaa tctaaatcaa gaggttatga agatactcca
    28261 gaaaaacaaa gacgttttgc tggtgaaatc aaaaaaatgc aagataaatg gccagcatat
    28321 attgcgcatg atccatttta caatgataat ttaacaaaag aaggaatcgg cgacttttcg
    28381 ttgagaccag attaaactat aataaaaagc tgttatgttg tgattcgctc gcacataacg
    28441 gctttttata gttttttgtc aaaaaaaggc agaaggtgcc gactcaaaaa aataagtcga
    28501 ggttgggaca gaagtgttta actccgagaa ataagaagaa attcacgaaa attgcttttc
    28561 aaatttttgt gaatttcggc ttatttaaga agaagttgct tctgctccca ccgtttattc
    28621 gtttttaaag aatgagacaa aagtgtttct tacttttgtc ccacgctctt attcatgctc
    28681 agagcgccaa tagatacaaa atcatagcca aagtttcacg aaccctagct gtcaaagaat
    28741 cgatatttta ttttaatata ggctatttta aaataaatgg tttaaggtat tcctctacaa
    28801 aagccactct atcaattatc atgggtttaa aataagaagt gatggagata accagattgt
    28861 tcttagcgtc aatataaaga acatttccac tattaccaat tgctgaatat atttcgttct
    28921 cagaatctaa tacccaccat aaatagccat atctcatatt ttgtaagtct tctaaagcac
    28981 tggttctagg tttgaacatc tcgtttatcc acatgggtgg tacgatttgt tttcctttat
    29041 acatcccttt atttaggcat aatacaccaa tttttgccag atcacttgcc gataaacaca
    29101 aaccatatcc tgccgtcccg atatttagtg gatcacaaaa ccagacattg gttttaggag
    29161 acttatccat tgtaaactgc ttatgttctt cagctgtttc agcataataa ttgacatggt
    29221 ttggtatccc tataggatca aatagatact tattggcaaa atcaacagtt gttagcttac
    29281 ttgtctgata caacaagcca gttaatatgt gtaaacagac agtttgatag ttgaattcgc
    29341 cggttatacc ttttcttcct cccaataaat ctagtgatgt ttttgtccaa tcttcacttg
    29401 aacagacttt tgtccatgga tcgcctttac atttgtaggg tgctttcatt gttagcaagt
    29461 gcttgattgt aatagcgtaa atagttttct ccccgcgttt cactttatac tctggaaaat
    29521 aatctaatac tttatcatcg atacttttga ttaatccttg ctctaaagca atgccaatca
    29581 gcaaagatac aatacttttc gttgctgaca tgatatgaca agtatcgtct tttttataac
    29641 cattccattc atctgtataa acttctaccc catccttata tgcgacaatt tgacatatat
    29701 ttggttgtcg aaaaccaata aaatcatgca actcttgttt attcataaga tattacctca
    29761 ctttcttcta taagcataat gtcattaaaa atcgatttca attttttcga ttcttcacgt
    29821 aatacaggta ttcttatgga ctagacagcg ctttgggaag atggattctc tgaaaaatat
    29881 aaaggttcac tttatgagtg gataaaaaaa gcagcaaata cttcgacttc tttaatttac
    29941 caacattagt gaaaatcgat tcatctggag atttgtaatt tagagtcctt gtcttgatta
    30001 gaggtgtata aagcttttta ttagacattt ttaaattcca ttacaatttg cttataaact
    30061 aggtttttaa aggtgactat ggtaagataa tagagatatt attttgtgat taggagtgta
    30121 tatatgaata aaaatggaga atggagtgct gcacgacgga tattcattat attaatggat
    30181 gttattgtat acaatgcagc aatatatagt agtttcttac tgaagtttcg tggagagatc
    30241 ccattacgaa atttagaaac tttccaacac tcagcaatta ttatttcagt gatttttatt
    30301 gcgttgaaca ttttgttggg tgcatatgtt ttttataatc gaatgatcag tgacatcgtg
    30361 tttgtcacag tcatcggtca ggtattgatg acactaggga tcatggtagt gacttttgcg
    30421 ggccgctggt ttgcttttcc acgtcttgtt atcttacttt catttgttct cggtacgctt
    30481 ttcttaagta tctatcgtat tctcgtatat aaactttatt tacgcgtaag tcgagataaa
    30541 aaggtcgtca ttattgggtt agaaaaggat gtcgcaccag caatccaaaa ttttggttca
    30601 aagaaaaaca acaaacataa agtcgaagca gtcattcttg ataactatta tgcaaacatc
    30661 aaaaatatga ttaaagacat cgatattgtc tatcttgctt ctcatatcga agaaactgaa
    30721 aaaatcaaaa tctatcaatt agttactaaa aatgaaaaaa aattgttttt gaatacaaca
    30781 tttgaaaact tgacattgat caatccaaat attatgaatt tcgaagatga aagtattatt
    30841 gaagcatctg gatttagaat ccaacctgaa tatgaactat tcaaacgttt gtttgatatc
    30901 atcgtttcac ttgttttatt agttattgct tcaccattta tgttattcac agcaatttta
    30961 gtcaaagtga catcaccggg accaatcatc tataaacaag tgcggatcac aaaaaatcaa
    31021 aaggaatttt caatctataa attccgctcg atgaccgcca cagccgaagc aaaatctgga
    31081 ccagttttag ctaagagcaa tgatgcacga gtaacgcctg taggtaaatt tattcgagct
    31141 gtccgctttg atgaattacc acaaatcttc aatgtgctga aaggcgatat gtcgatcgta
    31201 ggaccacgtc ctgaacgtcc tttcttcgtc gatcagttca atgcagaaaa cccttattac
    31261 tacttacggc ataatgttcg tgctggtatc actgggtatg cacaagtcta tggaaaatat
    31321 gtctctgatt acaacagtaa attacgtttt gatttacttt atatcaaaaa atattcattg
    31381 atgcttgatt taaagatctt gctgcaaacc atcaagatcc tatttgataa aatgtcctct
    31441 caaggacttg aagaagacga aaatgtgatc tcattggcag aaattgcttt tccgaatgaa
    31501 aaaatctttc gctagttggg aggcgtaaaa atgaacaatc cgaaattcag cataatcgta
    31561 ccagtataca atgcagaagc aactattggt cgaacgattg atattctaaa agaattggat
    31621 tatgaagagt acgaagtcgt tttagtaaat gatggatcaa cagatcaaac acaggaaatc
    31681 attcaagaac tgattgaaaa tgatgaacgt tttgaattga ttactacgac caatcaaggg
    31741 cccggattag caagaaacga aggaataaga cagtcaaaag gagaatatct cttattcttc
    31801 gatgcagatg acacgccagt aaaaacgatc ttgtcagatt atgatcattt gctagaaaag
    31861 agtccaaaag cggatcttgt tgttagttcg tttgtttttc gtacaatgga cgagggaaga
    31921 atcgtttccg aaaaagaaaa cttagttaca gaatgtcact atctaactca cgaagagttt
    31981 ataaaagaca tgtatcagtt aatgaatgaa cagttgatgt atgttgtatg gaacaaatgc
    32041 tatcgtagcg atattctgaa aaataaccaa attctattta aaacttataa tagttgtgag
    32101 gatcgaatat ttaacttaca ttattatgaa tactgtcatc aagtgatcat gaacccaaaa
    32161 gtagaatata tttatgaatt tgaaggtggg aaggggatca ctaatcaata ccgacctaac
    32221 aagttcgaaa catttaaaga attctattca ttagcaaata ctgtaacaga cgatattaat
    32281 aaagacggta tggcggcgct tcttttaaaa gggacaactt cagttatttt ttctatttat
    32341 agtacctctg caagaacttc aaaagagaag aaagacgaag caaagcagat attgagtgat
    32401 ccagtgatcc gagaagccaa gcaaattgct aagacggatt cttcagcaaa aaaaataaca
    32461 aagttgcttt acaatatgcc agctccacta tttttatctg ctgtaaaagt tggaagcttc
    32521 gttgaagtga aaatgccagg gttaatggct gctttgaagc gagtatatta gttaatggag
    32581 gaaaatataa tgaaaagaat tttgcatttt cagggacgaa tgggtttagg tggagcagag
    32641 tctttcatga tgaatttata tcgtaaaatt gatcgtacaa actatcaatt tgattttttg
    32701 atttatgaag attatgcaga tgttcaagac tatcattcag agattgaaag attaggaggc
    32761 cgtatttttg ttgtacctaa tcctaagaaa aatattttta aatatttaat agaagtgaat
    32821 aagttactaa aaaaagaatc tttttctata gttcacaatc aggtttattt tggcggggga
    32881 attaatttat ggttagccaa aaagaatgga atcagacaga gaattgctca tagccatgca
    32941 actgaagatg gaaaatctca aaatattgta atgaatgtat tgcgtaaatt tttaaccaaa
    33001 ttgttgttac aaaatgcaac agactacctt gccgttagtc aagaagctgg tgaaagtctg
    33061 tttcaaaacc acccctttga gatagttcat aatggtattg atttagagct ttatagtaaa
    33121 aattcagaag ctaaggttaa taagagaaaa gaattggata tctcaatgag tacttttgtt
    33181 gtgggaaaca ttggacgatt agagaaacaa aaaaatcaat cttatttgtt agagattttt
    33241 ttagaaatac taaaaatgaa ttctgattct tacttgattt tagtaggtga agggtcactt
    33301 agaaataaac tgaaagccaa agcagtagaa ttggatatag agaaaagagt aaaattttta
    33361 ggagaaagaa acgatattcc cgagttatta tctgtgatgg atgtttttgt aatgccttct
    33421 ctttatgaag gtctgccaat ggttggatta gaagcacaag cagcaaaatt aaaattagtc
    33481 ttagcagata ctatttccaa agatacaaag ttaacaaata atgtggattt tgtatcatta
    33541 gatgaaacac cacaagaatg ggcaaaaaaa gtaataaaag agccgtatgc taataaaata
    33601 acacaagaac taaagagtta tgatgtttcg tacactactg aacaaatgga gagtatatat
    33661 agtagagatc attaaaaatg ttcaagatat tttaggagtg attatttttg aaaatatgtt
    33721 atttgatatt ggcatacaat gatattggca acttaaagag attggtcaat cgattgaacg
    33781 aaaatgcagt ttttattatt catatagata aaaaaactga tatagaacca tttattgaag
    33841 catttaaatc atatgataat gttgaatttt tatgtaataa aaaccgtgtt aaaatttatt
    33901 ggggtggttt ttccattgta caagcagaaa tcaatttagt aaagagagca ttacaaaatg
    33961 agaaatattt aaaatatgta ttattatctg gtgctgatta tccaatcaaa gataatgagt
    34021 atatttataa ttattttaaa aagaatagtt cagtggagtt tattcgtgga atagatctag
    34081 atcaaattaa acataaagaa ttttattata aacatataga tgtatatcaa aaacatgatt
    34141 atcctagaat taataggaat aacacaactg catttaaaat ttttagagct ataattaatc
    34201 gttgtctgag gatgattaaa cttcccccaa aaattagaca ccataaattt gatttgtatc
    34261 atggttctca atggtgggct ttgtcgaaag aatgcctaac agaattaata caaatgtatg
    34321 aacaaaatca acaagactac ctgaatttta aaataggtat gtttgcccca gatgaaaaat
    34381 tttttcatac actttttttt aattcctcgt tcaaaaataa aaatgttatt ggaggaccag
    34441 atttaccact tgaattgaaa aatattgaag aaactacttt acaaacttcg aaattagcaa
    34501 atattcatat tattgatcct tccatgaaca aatggtttga tgaaagggat atagatcaaa
    34561 taaaagaaag tgaaaaatta tttgtaagaa aagttaaatc ggattactct gataaactat
    34621 taaatagaat tgataaagaa attttgaaag ttggaaatat agatgaatag aatagtacct
    34681 gttttagaga agagtttatt aagtcgagat gcgtttcgag taataaattt aatcatttgt
    34741 ctgctttatt ttatgcctag tacttttaat gtaactaata tcccgatgaa aatagctttt
    34801 gcttggggtg gaattatagt tttgtatgag gtttttataa agaaaaattt ttttaaaatg
    34861 cgtttttctt ggctactgat tggagcaatg attagtttta tcttaactat aatcattaac
    34921 agagaaaatt ttttaattcc atctatttat aattttggat atttgctgat tactttgata
    34981 gtaatttttc ctgcagactt ttcacaaagt gaagaggaaa aaaagaaaaa aatggtgtat
    35041 tttaataatg ttttcattat cataattttt ttagctgcgc taatatctat ctatcaattt
    35101 atttttttga tttcttatca tgtcccaaca ggaacgccag gattacttgc aagacaaggt
    35161 tttattgaac atcggttatt tggtgtctat acaagtccaa atgttggagc tatgtttgga
    35221 tatacttcta ttattttaag tttaattagt gtattaattt caaaaataac aaaaacgatt
    35281 cgtgtttttt atatgatgaa ttttatcgta caaatatttt atattacact ttcttcgtct
    35341 agaggtgccc aggtagtaat ttgttctttt ttagtattat ttcttttgtt gtttgccaat
    35401 tcaaaattta gaaagagcat tagagaagta ctacctgtaa aaatcaaatg gatggtaagc
    35461 atattattag ttctattggt atatttttct tttggtacta attatgctaa ggatttttta
    35521 gcaacaattc ctgtatcgat tgatagaaaa gtagaagtta tagagtcaaa tgaatcagat
    35581 aaaactccac ttccagaaaa agaagtaata ttacagcatt ctagtgataa ctccgaaatt
    35641 tcagctggtc gttttacgat ttggaaagct gcgcttaaag ttataagacc aactttgtta
    35701 tttggttatg gagagaccga tttctatggg aatagcgatg caaaattttt gaaaaaagta
    35761 gatcttgata ctacagatgt gaatgaacta aaaagagcac atggaaacat gcataatgga
    35821 tttcttcaag tacttgtatc aagtggtata attgctttta tatgtatcta tgctttctat
    35881 gtgttaaata tctttagttt actcaaaaca ttttttagaa gtaaagtgaa ttatgcgttt
    35941 cttggtattg ttttaatttt tatactatct atttttatag atgaaatggt ggaggctcat
    36001 gtacttttca ataagcgcga tgtcatttca attgttttct ggtattattt gggaagcatt
    36061 tcttacttgt atttaaaaaa ggagaattaa tatgaagaca gctttcattg cttggactcc
    36121 tttacatttg attaatatat taaatgttta tcaaaatttt taccgagaat caaaaggaga
    36181 tttatttatt tattctgaat ttgaaaacgc tagaagatat agtgagcgta taaaagaatt
    36241 agggctattt aatgatgttg tttttgtgaa tcaccggaaa atcggttctt cctttaaacg
    36301 taaaattaac ttgttaacta accataatca atttttctcg gatgatttat ccgtttatga
    36361 tgaaattttt atacaggggg aaaattattt cacaaaaata cttttctcca atgtttacaa
    36421 aaaaaatcca gatgtaaaac taaattatat agaagatggt ttgggtactt atttgaagaa
    36481 gagtatattt tcaacaagta aaaacgttca aagagttttt aaaatattaa ataaaaatag
    36541 catcttcaaa aaaaaaattg acgattattt tgtctattgt ccggaattgt tactttatga
    36601 tgtaaaaaat ataaaaaaaa ttcccaaaat agatgaaaac agtaaattga tgaaaaacat
    36661 acaatcaatc tttgggatag aagaagtttt tgtcggagat aaatgtatct tttttgatca
    36721 acctttatta tctgatggtt atggcataga tgaaacagat attttcgcta aagtaaatag
    36781 tatattttct ggaaaaaaag aaactttaat taagcttcat cctagagcaa ggacaaatcg
    36841 ttatggtgaa aaaaacatat tgaattccag tttaccgttt gaagtcttgc tacttgaaaa
    36901 tgacttctct tcaacacttt tgattagtcc tatatctaca atttcttttt caccatctat
    36961 gatgtttgaa aagacgatca actctattat gttggctaaa ttaattttaa atgaatatac
    37021 agcattatct gaagataaaa aagaaacatt gacaaatatt gttcttttct gtgaacatta
    37081 taaccgtcta tcagaagaaa aaattttact cccagaaaac tgggcagaat taagaaagtt
    37141 ggtagagtat gggattattt aacacacttt ccaagtcaaa attagttaag tccagtttct
    37201 ggtatactat agggaatttt tttattaagg gaatttcatt cataactatt cctatttttg
    37261 taaatattac tactcaagca gaatatggtt tgattaataa tttcacttca tttgtatcaa
    37321 ttttttcgat tcttgttggg ctaagcctaa attcggcaat taataatgca agttttgact
    37381 ataaagatga cataaatgaa tttatgtcat cggtactttc tctagctaca ctttcgttaa
    37441 ttgtgttctt attaataggg aacatatatt ttttgttttc aaatgctttt tttgatatga
    37501 accaacttgt atttaatttg atgttattac aaagttttgc tagttttgta attagttata
    37561 tccagtctta ttttacgatt aactttaacc attttaaata tttgatttta tcttttatat
    37621 ctactttttt gaatattgca atctctgtag ctttgatgca gacattatat tttgatgata
    37681 aatatgttgg cagagtagtc ggcggaacac tgtcatttgt gttgataggt ttagtaattt
    37741 atttaagaat aatgataaag ggtgctcatt tttttgataa aaaacagtgg agatacgctt
    37801 taaaaatctc tttgccgcta atcccacatt ccttagcaaa tatagtttta gcacaattcg
    37861 atagaattat gattaattct tatttaggtc ctgctgcggg gggaatatat tcctacatta
    37921 gtaacatagg tattattcta agcgtaatat ggatgtctac taataacgcc tgggttccat
    37981 ggttctatgg tgagatgagt aaaaataatg aaaaaaaagt gaagaaagtt agtaactatt
    38041 atttagtagt ctttactttg attacgatga ttgtaatggt agtttcgatt gatttagcaa
    38101 aatttatggc tccgaaagac tattattctg ggttatcttt agtggttccg ataaccttag
    38161 gctatttctt tcagttttta tatagtttac cagttaatgc tgaattttat gagaaaaaaa
    38221 catcgtttat tgcgattggt acagtagcaa gtgctatagt taatatacta ttaaacatga
    38281 ttttcatacc taggttagga ataattgctg ctggatacac aaccgtattt acgtattttt
    38341 tactttttat ttttcattat aatatcgcta aaaaaattac gaataaacaa ttatttgaca
    38401 caaaaaaaat atgtatcata ataatttttg tatcaatttt ttctttgata cttcatattt
    38461 taatcaatca aatgttgatt cgttacgttt tgacatcatt attgataatt agtttagtta
    38521 tatatttttt aaagattaag aatcgaatta tagatgacta taattcatag gaggagatat
    38581 aagtgtttaa aggaaaaaca atattagtaa ctggcggaac tggttccatt ggaagtgaaa
    38641 ttgttcgtca gcttttaaaa tatgaaccaa aagctatcag aatttatagt agaggtgaag
    38701 aaaaacaatt ttatatgcaa caagagctct caaatcacac taatttgaga tttttaattg
    38761 gtgatatcag agactctcaa aggattgatt atgcatgtcg tgatgtggat attatttttc
    38821 atgctgccgc aatgaaacac gttccagcaa gtgaatataa tcctatggaa gctgtaaaaa
    38881 caaatgtgat gggaactcaa aatgtaatag atgcagcgat caaaaataat gtaaaacatt
    38941 ttgtaggtat cagtacagat aaagtagtga gtcctactaa caccatgggt gcgacaaagt
    39001 tattgagtga aaaattaata atagctgcca atcagtataa aggaaaaaca gaaacaatat
    39061 tttcttgtgt aaggtttgga aatgtcatgg ggtcaagtgg atctgttatt cctcttttta
    39121 gtaaacaaat aaaaaacaat aaagatatta ctttgacaga tgttgatatg acacgattta
    39181 tgatgtcaat accggatgct gcaagattag ttctgtctgc tgctatgaat tcaaaatttg
    39241 gagaaacata tgtcttaaaa atgccggcaa tcaatatttt aactttagct caatcattaa
    39301 taaaaatata taatgataca catgatgaaa aatatagagg tgaaataaaa gttgtaggta
    39361 tcaggccagg agaaaaatta tatgaagagc taatgactac agacgaaatt gaacgctcat
    39421 atgaaaatga taaaatgtat atcattccac cacactatca tgctactgac gaactgtaca
    39481 aagattatga aaaaattaaa atcactgcat actcttcaga tgcaacagaa ttaatgagtg
    39541 gacaggaatt tattagaatc gcaaaagaga ataatgtcgt gacttggtaa ggagttttat
    39601 gatgaaatca gaagtatatg taattgcaga aattggtgta aaccataatg gaagtctaga
    39661 tttagcttta gaaagtattg ataaagctaa agaatgtgga gctaacgcgg ttaaatttca
    39721 aacatttaaa acgaataagc tagtttccaa aaaggctcca atggcaaaat atcagaagga
    39781 taatcttaaa gaggacagtt ctcaatttga aatgctaaaa aaattagaat tatctcaatc
    39841 tgattttatt agaataaaag attattgtat acaaaataaa attgattttt tgtctactcc
    39901 ttttgatgaa gaaagtgcag actttctaaa acaaattggt gtacaaggat ttaaaattgg
    39961 ctcaggagat ttaacaaatt taccttttct tagaaaaata gatatgtatg ggttgccagt
    40021 tttattatct acaggtatgg ctgatattca tgaggtcagt gaggctgtag attgtttcat
    40081 agatagtcca gttactattt tacattgtac ttcaaattat ccggctagtt ctgaagatat
    40141 taatttattg gcgattaaca cattaaaaga aatgttcggg atacccgttg ggtactccga
    40201 tcattcattg ggatatgatg ttggtatttg tgctgttgcg atgggtgcta aggtaattga
    40261 gaaacatttt accttggata aggaactacc tggtccagat cataaagctt ctttagatcc
    40321 tcaggaattt gcagattttg taaagcatat tagaaacact gaaatatttt taggtgatgg
    40381 tgttaagcga gcaatgcctt ctgaacttag tacaaaagaa gtatcaagaa aaagcctagt
    40441 ggtcactgag aatttaaatg tgggagatat tcttacagag aaatctctta caataaaacg
    40501 tcctggaaat ggaatagctc ctaagttttt atatcaatat attggcaaaa aagttaaaag
    40561 accaataagt gcagatagtg ttctgcttga ggaagatgtt gaatgaaaaa aatacttata
    40621 gtaagtggaa cacgagctga ttatggaata tataaacctg ttgctgagaa tttactacaa
    40681 gataattggg atgtatcatt tgttgtttct ggaatgcatt tatcccataa atatggattt
    40741 actaaagaat tgatcttagc tgacggattt agaattagtg gagaagttca aagtttgttt
    40801 ttagagaaca ataagggaaa catggctcgg tctgtggcat tagagataaa tggtttcaca
    40861 aatatatttg aacaaactag ccctgatttt gtattattac taggggatag aggagaaatg
    40921 ttggcagctg cgatagcttg tttgtatctt ggaatcaaaa cagcacatat tcacggaggc
    40981 gaagtgtctg gtactgtaga tgaatcaata agacatgcca taacgaaaat agcatctgtt
    41041 cattttgctg ctacggaaaa aagcaaagag cgtttaataa aaatggggga agattcttgg
    41101 agagtttttc ccgtcggagc tcctagaata gatactattt taaataatag attacctagt
    41161 tttagagata taaaagaaaa atatcatcta aaatttgaaa agaaaaaata cgttttgcaa
    41221 gtatttcatc cagttgtaac cgaactagaa aatatagaaa aacaaatttt agctttgatc
    41281 aattcaatgg aacaacaatc tcaaccaatt atttgcattt tacctaatag tgatgctggt
    41341 agcgaaatta tcagaaaaat gtaccagaaa tatttaaaaa cggatattat ttatattacg
    41401 aatttagagc cggaggaata cctgactata ttaaaagagt gcaaatttat gatcggaaat
    41461 tcttcttctg ggataattga agctgcatca ttcaaaatac cagtaataaa tttaggaacc
    41521 agacaaaatg gacgagaaca atctaaaaat attataaatg caaatctaaa tgaaaatgaa
    41581 attgaaactg ctttgaataa aatacaagat cctcagttta taaaaagctt gaaaaatgtt
    41641 aagaacatct acggtgacgg caacagttct agaagaataa caaaaacatt gaatcaaata
    41701 ttgaatgatg gggaagatat taagtggatt caaaaacaaa tagcttatta aaatatacta
    41761 gtgatccata cattattatt ggggctggcg gacacgcaaa agtcattatt gaaaccttaa
    41821 gattagaaaa taagttaata tatggatttt ttgatgataa gcaaaataaa atgcaagatc
    41881 tgaaatatct tgggaaaata aacgaattga atagctgggc ggatagcaaa aaaaaaatct
    41941 ataaatttat tgtagctatt ggtgactgtg tagtaagaaa aaagattata aaaaaattga
    42001 atatgccaag tgagcaatat ggaatagctg ttcatccaag tgctatagtg gcaaaagaaa
    42061 tttcaattgg ttatggaact gttatttttg cgaatgctgt aattaaccca gatgctgtaa
    42121 ttggagagca tgctataata aacacaggta gcattgttga gcatgattgt agaattaata
    42181 actatgttca tttatctcca ggtgtatgct tagcgggtgg agtacatgta ggtgtaggaa
    42241 ctcaaatagg aattggttct caatgtatcc agatgaagaa aattggatct tggtgtatga
    42301 taggcgcagg gagcactatt gttaaggata ttccctcaca ttccttagct tatggcaatc
    42361 cagctaaaat taagaaagaa ggaattaatt ttgaattcta gaattttatt atcaagtcct
    42421 catatgggag gaacagaaga aaaatatgtt gctaaggctt ttaaagataa ttggatagcg
    42481 ccattaggtg aaaatgtgga taaatttgaa gaaagtatta caaaatatac tggttctaag
    42541 ggcggagctt ctgcgttaag ttcaggtaca gctgccatac atcttgcctt aagactgctt
    42601 aatgttggaa aaaacgatat tgtctttgct ccttcattta cttttatagc tacagtaaat
    42661 cctattttat atcaaggggc tgtaccagtg ttcattgact cagaacctaa tacatggaat
    42721 atgagccctg ttgcactaga gagcgcatta gaagaagctg aaagaaacaa ccaattacct
    42781 aaggcaatca tcgtagtgaa tttatatggt caaatggctg attatgaacg aattttagct
    42841 attgcaaacc aatttaatgt tccagtgata gaagatgcag cggaatcgtt aggttctact
    42901 tataagggaa tttcgtcagg cttatttggg acaattggga tctattcatt taacggtaat
    42961 aagatcatca caacctcagg tggaggagct ctagtgtcta gtgataaaaa atatgttgag
    43021 cattcaagat ttttagcaac acaagcaaga gatcaagcac cgtattatca acatagcgaa
    43081 ataggttata attaccgtct aagcaatatt tctgccggta tcggacgtgg acaaatggaa
    43141 gtattgaatg atagagtagc taaacgaaga gaaattttca atcgatataa ggaagctttt
    43201 tctggaattg atagaattga aatgatgcca gaagtggatg gcatggtgcc aaatcgttgg
    43261 ttgtctactt taacgatcaa tgattataat tctattgatc aagtagttaa cgtaataaat
    43321 aaactaaatg aaaaaaacat tgaaacaaga gctttgtgga aaccactaca tttgcaacca
    43381 gtatttcaag gggtaaaaat gtattaccat gataataatc ttagtgtgtc agaaaagtta
    43441 tttaatagcg gcttatgctt accttctgga agtaatatga cagatagtga acaagaattt
    43501 gttattgatg agtttaaaaa aatattcaag taggtgtgat attttatgaa cataggaatt
    43561 attggtttag gttccatggg gaaaagaaga cttagactca ttcaagaaca ctttaatgat
    43621 attttactat gtggtgttga tactaatgag gcgagacgaa aggaagttga aaaggaattt
    43681 ggaataccaa cttataatag tctaacagag gcaaaaaatt tgtttgaaat aaattcagtt
    43741 tttgtttgta catcccctat aacccatgaa tttattataa aagaggcttt aaatttagat
    43801 tgtaatatct ttacggaaat caatttatta aatgaatatt atgatgaaat aatcgaagta
    43861 gctaaaaaga aagatagatt actttatcta tcttctacat ttttgaagag aaaagaaatt
    43921 caatatatta agtctaaagt gacgcataat aaaaaaattt cttatcaata ccatgtagga
    43981 cagtatttac ccgactggca tccttgggaa gattatcgca atttttttgt ttcaaacaaa
    44041 aaaactaatg ggtgtagaga aatattcgct attgaattac cttggattat agatacattt
    44101 gggaaagtta aatcgtttac tgtaatgacc cagaaattat ccaatcttga tattgattat
    44161 tcggacagtt tcactcttat tattgagcat gaaactggta tagttggaac tttaagtgta
    44221 gatgttgttt caagagtagc taaaagaaat ttaactataa ttggtgaaaa gattttaata
    44281 gaatgggaag gtaacccgga ttctctattt tcatggaatg aagaaacttc tagtatgaca
    44341 gatattcaat tgtacgatga ggttatgcat gataataatt attcacatac tattattgaa
    44401 gatgcatatt tagaggagat taaagaattt ttcacgcttt tggaaaagaa aatggaaccc
    44461 caatatactt ttgaaaaaga taagtatatt attaacttaa ttaacgacat tgaggtaaat
    44521 taatgatgaa agtaattttt tttgggttag ggtcaattgg aaagagacat ctaaaaaatc
    44581 taataagcta tggaaaaaag aattctatta attttgatat aacagcttat agtagcagtg
    44641 gaaaaaaaga gtttgaagaa ataacgtata ttcaaaatag agacgatttg gatacacatt
    44701 atgatatagc ttttattaca aatccgactt ttaagcatct ggaaacacta aatgtaattg
    44761 ttgaaaaagt tgattacata tttttagaaa aacctgcttt ttctgagagt attgatctta
    44821 ctcaatataa ttatgattac aaaaatattt atgttgctgc tccactgagg tataaaaata
    44881 tcatggaagt tgttcgtaat agtattcaaa gtaaaaaagt atattctgta agagctattt
    44941 gttctactta tcttcctgat tggagaaaag gtactgatta tagaaataat tattctgcct
    45001 ttaaatctat ggggggagga gtagaattag actgtataca tgaattggat tatattataa
    45061 acctatttgg tttccctaaa tcagtaaaaa aacagtttgg taaatattcg aatcttgaaa
    45121 ttaacagtaa tgatttagca acatatatat tgagatacga tgataaaatt atagaaattc
    45181 atttagatta ttttggaaga gttcctacaa gaaaatttca attgtttact ttagatgaat
    45241 gtatcaatgt tgacttatta aataataaaa taagttttga agaaaacatt gttaaagaaa
    45301 tgcctgaatc tgctaatgat atgtatgaga aggagttgaa atatttcttt gaaaacgtag
    45361 taacaggcaa agaaaactgg aatgatttat atcatgcaaa cgaagtattg aaaatagctg
    45421 aggagaaata aatggaaatt ttatttacta tttgtggtag agctgggtct aaggggttta
    45481 aaaataaaaa tttgaaatat ttggcaggaa agcccctagt ccatttcgct ttagcaatga
    45541 tagatatcta tcaacaaaaa catcctgaac ataattgcac gacttgtttg aatacggaca
    45601 gtaatgagtt agtagaattg acgactaagt taaatccgtc tgtgaaaatt gtagaacgta
    45661 aacctgaatt agctacagat actgtaggga aaattgaagt gatacgtgat tcattcttac
    45721 aactagaaag agaagataat atatttgatt taattataga tttagatttg acttcacctt
    45781 tacgtgaagt ttctaatctt gaagaattaa tagatgaaca tctaaaaaat ttagataaag
    45841 acgtctactt ttcagttgtt tctgcaagac gtaatcccta ttttaatatg gtaaaaagaa
    45901 ttgaaaatga agttactata gttaataaat caagatacac atctaggcaa cagacacctg
    45961 aagtttttga aatgaatgcc tcaatgtatt cttttaaacc tgaatttcta aaaaaaagta
    46021 attatatttt tgatgggcaa tgtgggataa taaaaatgag agattatcta attttagata
    46081 ttgatagtga agaagatttt aaatggttag aatttttgtt tcctaaattt ttagaagatt
    46141 cttcggagct tcaagatatc tataattatt tatatcggag gtaaaaggat gagctgttat
    46201 cttatcaccg gtggggctgg cttcattggt tctaccttag ccaatcattt aggagaagaa
    46261 catgtggtaa tcgtcgtcga tgacttatca atgggaaaag tagaaaatct tgatatgacg
    46321 aaaaatatca cttttattga gggagatgtc gctgagaaat ccttgatgga agagatcatg
    46381 aaagctaata aatttgatta tatctttcat ttagcagcag ttgctagtgt ggcagattca
    46441 gttgcccgac cagtagaaac acatcgtgtg aattttgaaa gtgtattaat gattttagaa
    46501 ttgatccgca agtatcaacc tgatttaaaa cggatcgtgt ttagttcttc agcggctgtt
    46561 tatggggatg aaccgacttt accaaaaaaa gaagagtccg tgattcgccc attgacgcct
    46621 tatgcggttg ataaattcgc tgcagaacaa tatgtgctag attattgtca tttatatgat
    46681 gtacccggta gcgcagttcg ttttttcaat gtctatggtc caaatcaaaa tccgaattct
    46741 ccatacagtg gtgtgatttc tattctcgta gatcgctata agaaacaaat cgtaggagaa
    46801 gcaacttcat ttacattatt tggtgatgga agccagtcta gagactttgt ttatatagat
    46861 gatgtaatcc aagcattact tttagttgcg aatgaggaag ctgcactggg gaaacaattc
    46921 aatgttggaa cgggtaaagc aaccacactt ttggaattga ttcatgcaat caatgaaatt
    46981 ctcggtgtag aattgacact tgaatacaaa gaagagcgtt cgggtgatat ccatgactct
    47041 ctagcagata ttactaagat ccagtcaatt ggctatcaac cgaaatatgg tattttaagt
    47101 ggaatgacta attatttgaa aactgaaatc aattaaaaca tactaagata agattagagg
    47161 gtaaattcag gctctttgtc aataaggact gatgagtttt gtaaaatcaa atctgggata
    47221 gaagggctct ttgtcaaatg atgttggtaa agagaaatct tagaataatt tggacagaac
    47281 agaaagaaga aaacctcttt ctgttctgtt tatttggtta aaaatgtttt gccatgacga
    47341 atcataattc gtagtttgaa attgtaaaag ttg
//
LOCUS       DBBGSP010000020        45419 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000020 DBBGSP010000000
VERSION     DBBGSP010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 45419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.020"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            246..1115
                     /locus_tag="ACIZE9_001273"
     CDS             246..1115
                     /locus_tag="ACIZE9_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6093144.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1324..2349
                     /locus_tag="ACIZE9_001274"
     CDS             1324..2349
                     /locus_tag="ACIZE9_001274"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGC6093145.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2388..3338
                     /gene="manA"
                     /locus_tag="ACIZE9_001275"
     CDS             2388..3338
                     /gene="manA"
                     /locus_tag="ACIZE9_001275"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGC6093146.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3432..5135
                     /locus_tag="ACIZE9_001276"
     CDS             3432..5135
                     /locus_tag="ACIZE9_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6093147.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5137..7170
                     /locus_tag="ACIZE9_001277"
     CDS             5137..7170
                     /locus_tag="ACIZE9_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HGC6093148.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7181..7621
                     /locus_tag="ACIZE9_001278"
     CDS             7181..7621
                     /locus_tag="ACIZE9_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6093149.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7821..8948)
                     /locus_tag="ACIZE9_001279"
     CDS             complement(7821..8948)
                     /locus_tag="ACIZE9_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6093150.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8951..9628)
                     /locus_tag="ACIZE9_001280"
     CDS             complement(8951..9628)
                     /locus_tag="ACIZE9_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGC6093151.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9892..11658
                     /locus_tag="ACIZE9_001281"
     CDS             9892..11658
                     /locus_tag="ACIZE9_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HGC6093152.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11673..12110
                     /locus_tag="ACIZE9_001282"
     CDS             11673..12110
                     /locus_tag="ACIZE9_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6093153.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12123..13274
                     /locus_tag="ACIZE9_001283"
     CDS             12123..13274
                     /locus_tag="ACIZE9_001283"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGC6093154.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13336..14034)
                     /locus_tag="ACIZE9_001284"
     CDS             complement(13336..14034)
                     /locus_tag="ACIZE9_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HGC6093155.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(14027..15379)
                     /locus_tag="ACIZE9_001285"
     CDS             complement(14027..15379)
                     /locus_tag="ACIZE9_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HGC6093156.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15602..17002)
                     /locus_tag="ACIZE9_001286"
     CDS             complement(15602..17002)
                     /locus_tag="ACIZE9_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGC6093157.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17163..17900
                     /locus_tag="ACIZE9_001287"
     CDS             17163..17900
                     /locus_tag="ACIZE9_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HGC6093158.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            18025..18504
                     /locus_tag="ACIZE9_001288"
     CDS             18025..18504
                     /locus_tag="ACIZE9_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HGC6093159.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18501..19268
                     /locus_tag="ACIZE9_001289"
     CDS             18501..19268
                     /locus_tag="ACIZE9_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HGC6093160.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19498..20067
                     /gene="lepB"
                     /locus_tag="ACIZE9_001290"
     CDS             19498..20067
                     /gene="lepB"
                     /locus_tag="ACIZE9_001290"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGC6093161.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20171..20773)
                     /locus_tag="ACIZE9_001291"
     CDS             complement(20171..20773)
                     /locus_tag="ACIZE9_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HGC6093162.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20879..21109
                     /locus_tag="ACIZE9_001292"
     CDS             20879..21109
                     /locus_tag="ACIZE9_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093163.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            21100..21348
                     /locus_tag="ACIZE9_001293"
     CDS             21100..21348
                     /locus_tag="ACIZE9_001293"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6093164.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            21454..22038
                     /locus_tag="ACIZE9_001294"
     CDS             21454..22038
                     /locus_tag="ACIZE9_001294"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGC6093165.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            22041..23114
                     /gene="prfA"
                     /locus_tag="ACIZE9_001295"
     CDS             22041..23114
                     /gene="prfA"
                     /locus_tag="ACIZE9_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGC6093166.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23107..23946
                     /gene="prmC"
                     /locus_tag="ACIZE9_001296"
     CDS             23107..23946
                     /gene="prmC"
                     /locus_tag="ACIZE9_001296"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGC6093167.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23939..24118
                     /locus_tag="ACIZE9_001297"
     CDS             23939..24118
                     /locus_tag="ACIZE9_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093168.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24140..25165
                     /locus_tag="ACIZE9_001298"
     CDS             24140..25165
                     /locus_tag="ACIZE9_001298"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGC6093169.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25356..26600
                     /gene="glyA"
                     /locus_tag="ACIZE9_001299"
     CDS             25356..26600
                     /gene="glyA"
                     /locus_tag="ACIZE9_001299"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGC6093170.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26753..27700
                     /locus_tag="ACIZE9_001300"
     CDS             26753..27700
                     /locus_tag="ACIZE9_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HGC6093171.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27834..28463
                     /gene="upp"
                     /locus_tag="ACIZE9_001301"
     CDS             27834..28463
                     /gene="upp"
                     /locus_tag="ACIZE9_001301"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGC6093172.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28602..28844)
                     /locus_tag="ACIZE9_001302"
     CDS             complement(28602..28844)
                     /locus_tag="ACIZE9_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093173.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            28965..29037
                     /locus_tag="ACIZE9_001303"
     tRNA            28965..29037
                     /locus_tag="ACIZE9_001303"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28998..29000,aa:Thr,seq:cgt)
     gene            complement(29156..29794)
                     /locus_tag="ACIZE9_001304"
     CDS             complement(29156..29794)
                     /locus_tag="ACIZE9_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGC6093174.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29917..30549)
                     /locus_tag="ACIZE9_001305"
     CDS             complement(29917..30549)
                     /locus_tag="ACIZE9_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HGC6093175.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30900..31199
                     /locus_tag="ACIZE9_001306"
     CDS             30900..31199
                     /locus_tag="ACIZE9_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGC6093176.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            31694..33859
                     /gene="acm"
                     /locus_tag="ACIZE9_001307"
     CDS             31694..33859
                     /gene="acm"
                     /locus_tag="ACIZE9_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HGC6093177.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(34131..34616)
                     /locus_tag="ACIZE9_001308"
     CDS             complement(34131..34616)
                     /locus_tag="ACIZE9_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HGC6093178.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    34706..35051
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            35096..35737
                     /locus_tag="ACIZE9_001309"
     CDS             35096..35737
                     /locus_tag="ACIZE9_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGC6093179.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            35756..36391
                     /locus_tag="ACIZE9_001310"
     CDS             35756..36391
                     /locus_tag="ACIZE9_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGC6093180.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            36409..37224
                     /locus_tag="ACIZE9_001311"
     CDS             36409..37224
                     /locus_tag="ACIZE9_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6093181.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            37543..38979
                     /locus_tag="ACIZE9_001312"
     CDS             37543..38979
                     /locus_tag="ACIZE9_001312"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6093182.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKSSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            39168..41600
                     /locus_tag="ACIZE9_001313"
     CDS             39168..41600
                     /locus_tag="ACIZE9_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGC6093183.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPI
                     DSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPT
                     VDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVG
                     VKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNH
                     PDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEV
                     KLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNI
                     SGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGI
                     HMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLP
                     MGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELF
                     EEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQE
                     ETSETLPDDNDM"
     gene            41830..42897
                     /gene="rlmN"
                     /locus_tag="ACIZE9_001314"
     CDS             41830..42897
                     /gene="rlmN"
                     /locus_tag="ACIZE9_001314"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGC6093184.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            42887..43093
                     /locus_tag="ACIZE9_001315"
     CDS             42887..43093
                     /locus_tag="ACIZE9_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093185.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(43090..44193)
                     /locus_tag="ACIZE9_001316"
     CDS             complement(43090..44193)
                     /locus_tag="ACIZE9_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HGC6093186.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            44745..45293
                     /gene="aac(6')"
                     /locus_tag="ACIZE9_001317"
     CDS             44745..45293
                     /gene="aac(6')"
                     /locus_tag="ACIZE9_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HGC6093187.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT        15538 a         7783 c         9271 g        12827 t
ORIGIN      
        1 atctgcggta ataagcccaa ccaaacgaaa aataggagga gctatttttg tttggctgtt
       61 cttattactt gatgcagaac agctttttca caacctcttt ttataagagt ttttactcat
      121 taatttacaa aaaacaagca aaatgcgaat tttctcacat tttttttaac aaaatcaaag
      181 ttattgcttg aaagaagaag aatccatcgt taaaataaag cttgacgtag aggggagcaa
      241 gaaatatgaa agattttcaa ttgggggctg ccacctattt aaaaagtgta gccattcggg
      301 tgaaagaccg agataaaatg attgattttt acaagaacgt tgttggcttt gatttgaaaa
      361 gagaagaaaa cgaattagcc attttaggaa cagaagaagc tggaagtgaa atgttgctgc
      421 tggaagaaag tcctagagcg aatgatcaca tgggggtgat caaaaagctg aaccgttttt
      481 cattgattat ccctagcaca gaagaaatgg cagatatcct ttgtcgtatc cgtaaaatga
      541 attatccaat caaagaagct ttagaagatc atggacgtat ggggattttg ctcgtagacc
      601 cagaagagaa tgaattggaa atttaccatg aagagaataa gaacgaccaa agagaaattc
      661 cagaaacaat ggatcaagaa gcattattaa gaaaatctga agaaaaattc agtaaactat
      721 caacaggttc ttattttgaa aaaatccatt taaatgttac taacttaaca aaagaacgcc
      781 aatttcttaa tcatgtactt ggtttgaagg tacataatga agaagagggc atccatgtat
      841 tgaatgaagg agatttccat gttggtttga cagaagctag cggaggcgca attgatttgc
      901 ctacagatga agtgattgga cttgattttc tgaaattcat gatcgatact gaaagcatgg
      961 aaggactgat tgctcacttg cagcaactat cagttgattt cttcttagac aaaaagcaca
     1021 cagtactcac aatctatgat gctataggaa tcgaatggtg gttcgtcagt gagccaaaag
     1081 aaaagaataa aactgacatt cgatgcgacg cttaactttt tctttcttaa cgattgtcgc
     1141 atgtctcgtc attttatgaa cggtcatact atcgcttatt ctagagatag aaagagaaaa
     1201 tagtataccg ggggaaactg cgcggttttt cgcgcagttt ttttgtgtaa aaaaggttga
     1261 ttcctcatag attaagcttt aagcttggac tgtaagaatc tgatagaaaa gcaggagaaa
     1321 aagatgtatc cacacacgaa acagcttatt ttgaaaaaga tggaagaagg attttatcca
     1381 ggtgtagcag tcgccttcat aaaagaaaat caagtagaaa catttacagc cggctttgcc
     1441 caagtcgttc ctgaaaagca gctgatgaca gaagatctgt tgtttgatgc agcctcactg
     1501 acgaaagtcg ttgcaaccac ttcattagtt ttacgtctat tagaagatgg aaagatagaa
     1561 ctcgatcaac cgcttcataa atatcttcct gaatttgaaa atcagacaat cactttgcgt
     1621 catttactga cacatacttc tgatatcaaa acatggatac caaacagaga taagctatct
     1681 caggaagaat tgatcgccgc ttatttgaag ctagaaccag gtgagcaact aggaaaagaa
     1741 gtaaaatata cagatgccgg tacgattctt cttgggttga tgctagagga aatttaccaa
     1801 gaaactgcag tggaaatctt tcaagaacaa gtattggaac cattaggaat gatgaacagc
     1861 ttatttcttc cttttccttc caaaaaaatc gttcccacag aacaactgcc ttcgggtgag
     1921 gttttgcgtg gacaaactca tgatccgaaa gcaagagttt tggctgaaca tgcaggtaac
     1981 gcgggtctct ttattgattt gaaagacagc attacttttg tccaaatgta tttgaacaag
     2041 ggaaaaatcc gtaatggtcg ttttttagaa gaagagacga ttgattcttt actgcaagat
     2101 caaacaccga aaaaaaatgg ctatcgttct ttaggatggg acttaaaaaa ggatgtagaa
     2161 gacggtcatg cgattctttt tcatactggt tatacaggta cgtttttctt gattgatata
     2221 aaaacacaag aagcgttgat atttttgtca aatcgcgtac atcctgtcga tcatcgtgcg
     2281 gagtatctca tatgtcgaga tgaaattgtt gaaaactttt tgaaagagaa agcggtatta
     2341 ccgaaataat gctataatag ctatgaaaaa tgagaggagt ttgaattatg caggaaccta
     2401 tgtttttaaa accagttttt caagaaaaaa tttggggagg aagtcgttta cgttcagtct
     2461 ttggttttga tatccctaac gataaaatcg gagaagattg ggcgatcagt gcgcatcctc
     2521 atggtgtcag tgtagtagaa aatggcgaat tcaaagggaa aagattagat gaactatggt
     2581 cagaacacaa ggaattgttt ggccatcctt cagaaccagt gtttccatta ttgatcaaga
     2641 tcttagacgc agaagatgat ctatctgtac aagtacatcc agatgatgcc tatgggatga
     2701 aacatgaagg tgaattagga aaaactgaat gctggtatat catcgatgct gaacctggtg
     2761 cagaaatcat ctatggtcat catgcaaaga caagagaaga actagctgag atgatcaaag
     2821 atgggcgctg ggatgacctt ttgaagaaag taccagttaa aaaaggtgat ttcttttatg
     2881 taccaagcgg aacgatccat gctattggta aaggaatcat gattttagaa acacagcaaa
     2941 gttctgacac gacttaccgc gtgtatgact acgacagaaa agatgcgcaa ggacaaacaa
     3001 gagagctgca tatccaacaa tcgatcgatg taacaactgt ccctgcgaaa acaccagaat
     3061 tacaaatcaa agaagtccga aaagggaatt catcgatcgt cacttattta gaaactgagt
     3121 ttttcaatgt atatgagtgg gatattaaag gaatcacatc tttcaaaaaa caagcccctt
     3181 atacattgat gacggtaatc gaaggagcag gagaccttgt cgttgacgga aaaacatatc
     3241 cattagaaaa aggaacaagc tgtattattc caaatggcgt ttctgagtgg gcggtccaag
     3301 gtgaactagc aatcattgcg tctgaaccag gcaaatagtt cccagatagc tgaaagcagc
     3361 agacggtttt tcgtttgctg ctttttctac ataaaatccg tccatcaata aatagaagtc
     3421 tggtgaaaaa gatggaatac aaatggaaag caaacaacag cagtcgcgtg tctatgaaac
     3481 aactgagaaa agctggacat cacttaaatg aaatgatcat gccaaatcta agtctgttta
     3541 tcgcttgggg aatcttgtca ttagcaacaa aaggtgtgtc tggcgatttg cacaccacat
     3601 tagaagaggt atgccattgg atgatccagc tgcttttacc catcttgatc agttattcag
     3661 gcgggaaatc ggtaggggga caaaaagggg cagtcgccgg tgcaattgct tctttagggt
     3721 tgatcgctcg ttccaatgct ccacaaatcg taggagcgat gattatcggg ccgcttgccg
     3781 gcatcgtata tgaacaattt gtttctagat tccatgtgaa attcaaggct ggatatgaaa
     3841 tgcttgtcag caacctacta gtaggactga ctggtagcgt tatttgtata attggaatcg
     3901 tttttattga accagtttta aatagtgttc acttgttgct cgcctccgtt gtgtcttggc
     3961 tagtcacaat gaatctgtta ccacttgtca gtctgatctt agaacctcta aaagtactat
     4021 ttttcaataa tgcaatcaat catggtgtat tgacaccttt aggaatcgaa ttctcacaaa
     4081 cagtcgggta ctcttcctta tttttgatgg aggcaaatcc tggacctggt ttagggatct
     4141 tactttctat cctttgtttt gcagaaaaac aggaaaaagt aaatgcgagt ggagcattga
     4201 tgatccatgc gattggcggg attcacgaaa tctattttcc atttgtcttg ctgcgaccgt
     4261 atctattttt agctgtaatg gctggtgggg caagcggcac gttgatattt caatggttag
     4321 atacgggatt agctgcacct gtatcgcctg ggtcactact cgtgattttt gccaatgcgc
     4381 cttatccaca actagctggg gtaagtatag ggatagcaat cagtacattt gtgaccttca
     4441 tttgtgcagc gatactattg aaattaccaa ataaagaaaa agagaacaaa acggtcaaag
     4501 aaaggggaga aatcttggaa ccatctatca ttcattccgt catttttgct tgcgactcag
     4561 gtatgggatc aagtgctatg ggagccgccc tgctgaaaaa gaaattagca gcagaaaaaa
     4621 tcgatctttc tgtcggatac agctctatct atgaattgaa taaccaagta aatcagctgg
     4681 ttatcgtgca acatgaacta gcgggtcttg caagagaaaa agtacctcaa agtcaaatct
     4741 atgtactgga tcactttttg gaaacagata tcttgctgtc acgaataaaa gaagcgatcc
     4801 aatttccaaa gcgggaagaa aaaaaagaga tagcagatat cacagaacaa aaaacgtcgc
     4861 ctgctaatat tgtatttttg tataaaaaca acagacgcgg ctcacaaact atgggcatga
     4921 cgattttaag tcaattagca aaaaaagcga aaaaacagtt tgttatctca aaagaatcaa
     4981 tagaaaaaat caaaatccaa gaagaaacga tttatatcgc acaaagagaa ctagctgtaa
     5041 ctgaacagct agaagaaaag atccctcggc tagttctagt tgaacattgg gtagctacga
     5101 atgaatacga aaaactcgtg aagggagaaa tataagatgt atttatcgcc cagagaaaaa
     5161 caattattag cagaatttct cagtagcccg tcacctgtat ctatccaaaa aatgatgaat
     5221 ttattgaagg tcagtaaacg gactatttac cgcgaattag ataatcttga agtctcattg
     5281 aaatcggtaa atgcttcttt gaaaaaagca gctagaggct catttgtcat tgaggcatca
     5341 gaagaagtat tagagcaatt aaaagaaaat acagatggga aaagtaatga cttatccact
     5401 gctaaacgac aacacgcgat tttagccgag ttgttactga cgacagagcc gttgagtctt
     5461 gctcatttca tggaatcata tcgcatcagt aataccactt tttatgcaga tatcaaacag
     5521 ttggaagaaa gtattcgcca actgcctttg gaaatcattc ggaaccaggg atacgagatc
     5581 gaaggaccgg aaaaataccg ccggcttctg acagcgaatg tattagaatt agaaatcaat
     5641 gaatatgaac tttttcatag tatttctttc gatgcatcac tgaattattt ttttcgattc
     5701 gttgatccgc aacatctatc tcttgcacgc aaagtaatcg gggaagaatt gatccaaaaa
     5761 aagaccaatc taagtgatag aaagcttgaa catttggttt tgatgctgac attgacgatg
     5821 gagcgtgtga cgaaaaatca tttactgaca aatgagacat ataatagtct ggcaaacaaa
     5881 gaattactac agacagctaa acgattgttt tcacggatcg cttctgagac aaaacaactt
     5941 tatccagtaa atgagatcgt cttttttgca ggattattaa atgacttcac gaactcattt
     6001 gatcagaatt tctttgaaga gacgttcgat acacagcttg cttatttagt aaaacaactg
     6061 attcaagaag taagtgaaga gacgaatgtc catttttatg aagatgaaac tttgtacaaa
     6121 atgctgttga ctcatttatc tggtgtgttt tcaagagccg ttttacaaga agagacactg
     6181 accaatccga ttttagaaaa aatcatggtt caatacgagg aagttgcgaa tgcaatccgt
     6241 aaagcagtag agcggatttt tcaagaaaaa aaattatccg aagaagagat cgcttatatg
     6301 gtccttcatt ttgcgaattc attggaacga agtccgaaag aaagcaatat cagtattgca
     6361 ggattttcgc caagtggatt agcttctact agcatgttgg aactacgatt gaaaaggtat
     6421 tttcccttca tccaacaaat tcatttctat cggattgctg atttaaaaaa aatcgattta
     6481 caagaagaat atgatgttgt tatttctaca tctattttac caggatacgg tggaaaatat
     6541 attttagtct ccccgctact gctagaagat gaagtcaagc agctaaaaga agctttttcg
     6601 catattgaga agaaaaaaag gcaaaaaatt acgtataaca gcaataacga gtggatgata
     6661 gaagatactt atgaggaaac aatgcatttc atggatcaaa tcaatcaatt actcggtcgt
     6721 ttttttatcc aagaactgga taatcctgag acgatttccg aaacgattcg cagcttattt
     6781 ccttattttc ctgaaggact agtaacggat gaagaggtgg ttcatcgccg gctgcttaag
     6841 cgatatgaac aagcacctat cggtattcct catacaaata tggggttatt ccatacatcc
     6901 agctcattga tttctaaacc gatcttttgt attttcaatt tgaaacatcc gttgaccatt
     6961 gaagggatgg atagacagcc agtcgatttg tcccgtatgt tagttatgct ggcgccttcg
     7021 ccaatccaag aaaaagacgg gattctttta ggaaagatca gtggagcaat catcatgaat
     7081 gacttgaaca ccgagatctt ccgctcagga aataaagaaa tcgtttatca gttgttagcg
     7141 aaaatcctga ttgaagaaat aaagaaatga aggtgaaaag atgatacagc taccagcaga
     7201 aaaaatattg ctcgatcaat cctatcaaaa ttggaaagaa gcgttgaccg agatcggcca
     7261 gtggatgacc caacaagggg gaatcaaacc ggcatatatc caatcaatga tcgaaagaca
     7321 agaaaaagcg agtgtctata tcgggaattt cgtagccttg ccacatggga ctgacaaaga
     7381 tgaagaagta gtagaagaag gaatctattt agtccaagtg cctgatggtg tggactttgg
     7441 aacaaaagag gaaccaaaaa tcgcgacact cttatttgta gtggctttaa aaaaagaaca
     7501 tcagttagcg gtgctccaag atttagcctt tttctgttca gacatcgacc aagtaatggc
     7561 gctcagtgat gcggaaacca ttgaagaagt ccaaatgatt tttgaacatg gacatatata
     7621 accaatgttc acagtaaaaa aagctgcctt gcatcaagta ataacttcaa ccaagataaa
     7681 aataagagga gctatttttg ttgggaggtt cttattactg cggatgcaag cttttgaaaa
     7741 ctatttattc tagaaaaccg tttatttgaa ataggggacg gtgacaaggt ttttgtcacc
     7801 gcccctatta tttttgtgtt ttaatagctc ttttttatat agatagtgcc catacctatg
     7861 aataataaaa cgatactcca tataccaagt gtcaagatac cattcatgaa agtaacctgt
     7921 tctgaagcta gtggcgagaa aatatctcct cctatgatca cattttgaaa atcaacataa
     7981 gaagttggca agtaatgact gattgattct atccatccaa tcgaagaaaa caagcgatac
     8041 tctgctaaga aaagacaaag aagtgtacct aaaagattga ctagagaatg ttcaaataaa
     8101 gcagatagaa gaaaactgat tgtacttaaa aagagcaccc acaacaacag gaacagaaag
     8161 ctctggaaaa gatactcata catcggcagg attcgtatct cctgaccaat gatcgttcct
     8221 acaggataac ggaagtctcc caaaccattt ttgattatta ctagtataga gacgatcaaa
     8281 aatggcatca cgagacttag catagctgca ccataataaa tggtaaaacg gatgctatgt
     8341 ttctttacca tactatccag taatagattg actagagaga ttacctgctt tcttttttca
     8401 taagagatga tggaagaaag aaacaaggcg gttatacata aaatcaaaaa actagaaatc
     8461 attcctgaaa aaatattttc gtagtaattt gctaaagaga gatgcgctgg caagtcaaaa
     8521 atagaatatc tttggatctg atgttctttc atataacgga gcaactcgac acgtttttgt
     8581 tgttcaatga ttggaattcc ttgtctttga ccagaaatca gtcgatccag tatatctttt
     8641 tcataatgat aagttgcttc gaccatttgc tggacattcc ctgtgttttt tgcatgtaag
     8701 attgcttcga tcagtttgtt gcttttctct aaactttcca caaattcttt ctcattctca
     8761 tcttctttca acgtttcaat caaacgttgc atctcttcat agttatgatt cagttcatcg
     8821 aattctgtat aagcaagttt atgatcaaaa aaaagtggga atgcaaagag cacgaccaac
     8881 aatagaggaa ataaaaagtt tactttgttt tttagtaaga gattgcgttc aaatgtaagt
     8941 aaagacatag ttacacctca tataatttac gataaatagc taaaatctct tccatatttg
     9001 aggattctgt gacgatttct ccatttttta gaaaacatgc tttagaacaa atcgattgga
     9061 tattcgcgat agcgtgggaa gaaagaagaa tcgtcttccc ctctttctgc cattgtctga
     9121 tgaggctatt caagatatca atacttcctg ggtctaatcc gttcaacggt tcatcgaata
     9181 acatgacaga tgaatcactg atcaagtaag cagcaagcaa gacatgttgt ttcattccta
     9241 gagacatttt tccaatcggc aaagtaaggt actcagtcat cttcaatcgt tggaaaacag
     9301 tttggcattc tactttgctc tgccaatagt atttgatcaa agtcaaataa tcaacagccg
     9361 atagatagtc ggataactga ttcgttgatt ctagaaaaaa gaaagaccgg cgataatctg
     9421 tataagcagt aggagagatg ttgtgaaggg acaattgatc ataagttgtt ggcagcagtt
     9481 gggcaatgcc attcagcaaa gttgttttgc caaatccgtt cggggcaatc aaagcagcta
     9541 cttctcctga ttctactaaa agattcaatt gtcgaatcac acgtttttta ccacgtttca
     9601 tgttcatgtt tttgatcagt aatgtcatag ataggcctcc aatataaaat ttaataacat
     9661 aatagaatgg aaaacatcta aattaaatgc taacaaaagt tattgtttgc atattataaa
     9721 aaaattaaaa taacagtttt atttaaaatt gaagttttct gataccgaaa tctttttatt
     9781 ttgctgacat actcaaacct ttggcacaaa gtttcgtgcc aaagtacgac tatttctctt
     9841 tttagtaagc ggatacaatt agagtatcaa aaggagagag ggagagacaa aatggaacgg
     9901 acgattccca aaaacaacat ttcgctaaaa gcgagggtac aaaaattagg cagtacttta
     9961 tcaagcatgg tcatgccaaa tattggagca ctgattgcct ggggtgtatt aacggctcta
    10021 tttatcccag atggttattt accaaatgag gctttcgcta ccatggtaag cccaatgcta
    10081 acttatctga ttcctttatt gatcggttat actggcggaa aagtaattgc tggtgaccgc
    10141 ggatcagttg ttggggcaat tgcaacgatg ggtgtgattg tcggaacaga tattccaatg
    10201 atgctaggcg cgatgatcat gggacctctt ggtggatatg ccatcaagaa atttgatcag
    10261 ctattccaaa aacggatcaa atccggtttt gaaatgctag tcaataattt ttcagcaggt
    10321 cttatcggtt ttggattagc gttattaggt ttttctgcga ttggtccagt tgtcgatgca
    10381 ttgactcaag caatggcaaa aggtgtagag atcattttat ctgcccattt gattccattg
    10441 acaagtattt ttattgaacc agcaaaaatc ttatttttga ataatgcaat caatcatggg
    10501 attttgacac cattgggaac tgaacaagta gcagaggctg gaaaatctat tctattcttg
    10561 cttgaagcaa atcctggtcc aggacttggc gtattacttg cttttacttt gtttggcaaa
    10621 ggagcagcaa aatcttcagc accaggagcc atgatcattc actttttagg cgggatccat
    10681 gaaatctatt ttccttacgt tatgatgaaa ccgttattat tcttatcagt tataggcgga
    10741 ggaatgtcag gaagtttcat tttccaattg atggatgctg gactaagagc gccagcttct
    10801 ccagggtcga tcattgcgat tctagcgatg acaccgttca attcttacct tcctgttatt
    10861 ttgggcgtga ttgttgccgc agctgtttcg tttggtattt ctgcagtaat tttgaaagcg
    10921 gatgcgaaag atacaaatga agacttcgaa aaatctgttc aagagacaaa ggcagctaag
    10981 caagcttcca aaggtgccca aggtattcct caaggagcta cattctctgg cgtacaaaaa
    11041 atcatttttg cttgtgatgc aggaatggga tcaagtgcga tgggcgcttc gatcttgaga
    11101 aaaaaagtac aggaagcaga cttgcctcaa acggtgacca atcaagcaat cagccaactg
    11161 acagatgact cgaatacatt gatcgttact caggtcgaac tacaagaaag agcaaaacaa
    11221 aaagcaccga gcgcgcgttt tgtctcagta gaaaactttt tgaattcacc tcgatatgat
    11281 gaaatcattc aagaattaag cagcaagcag aaaacatcag tttctgaaat tgagaatgag
    11341 ccagcagaag agtttctttc agcaaacatc aaacaaatca aagagattct acttgtccac
    11401 gatgatcgtt ccggatcagc aacaatgggg atgaccgtgc tcaaagatat attagacaag
    11461 aaccatttaa ctatcccgtt aagaaaagtc aatatccaag atttaaaaga tgaacctgat
    11521 tcactgatcg tagccaaaga aagtttagcg gaaaaagtac agatggctgc acctcaatcc
    11581 attcatttat cagtcaacag catggtcaat ccgcaaaaat acgaatcgat tgcacaatat
    11641 ttgaaacaga cagcttaagg gaggaaaaca gcatgcaaag tttgccattc gacatgatcg
    11701 agctcaatcg atcttttaaa accaaagaag aagcgatccg ctattgcggt cagatgcttg
    11761 tagaagcagg gtgcgttgat gaggaatata tcgatgccat ggtagataga gacaaaatgt
    11821 tatctgttta tatggggaat tttatcgcga ttcctcatgg aacagatgaa gcaaaaaaat
    11881 atgtgaaaaa atccggcatc tgtgtcgttc aagtaccaga tggtgtagat tttggtaccg
    11941 aagaagaaga aaagattgcg actgttttgt tcggtattgc aggagtcgga gatgagcatt
    12001 tgcaacttgt acagcaaatc gcactttatt gcagtgatat ggacaatgtt gtccagctag
    12061 cagacgcgct cagcaaagaa gaagtaacgg aaaatctagc aattgcttaa ggagagagaa
    12121 aaatgagagc agtacatttt ggtgcaggaa atatcggtcg aggatttatt ggagaggttt
    12181 tggcagctaa tggatttgag attactttcg tagatgtgaa tcacacgatc attgatgctt
    12241 taaatgaaag aaaagaatac gaaatcgaat tagcagatga atcaaaagaa aaaatcactg
    12301 taaaaaatgt caaaggaatc aacaatcaaa caaatccaga aaaagtaatc caagaaatcg
    12361 ctgaagcaga tttagttact accgccattg gcccgaatat cttacctttt attgctgagt
    12421 tgattgcaaa aggtatccaa gaaagagaaa aggaaggaag cacaacatct ttagatatca
    12481 ttgcctgtga aaatatgatt ggcggttcag catttctaga aaaagaagtg tataaatatc
    12541 ttccggaaac atcatttact gacaaatata tcggctttcc aaatgcagca gtcgatcgaa
    12601 tcgtcccatt acaacaccat gaagatcctt tattcgtcca agtggaacct ttcaaagaat
    12661 gggtcattga cgatagccaa agaaaaaata aaaaaatcca attaaaaggg gttttatatg
    12721 tagatgatct agaaccatat atcgaacgca aactatttag tgtcaatact ggtcatgcga
    12781 ctgtcgctta tacaggtgcc ttgttaggtt accagaccat tgatgaagca atgcaagatg
    12841 cgttagttgt ggcacaatta aaatcagttt tgcaggaaac aggaagtttg ctgattgcca
    12901 aatgggggtt tgatgcagag cagcatcatg cgtatattga aaaaatcatt catcgcttcc
    12961 aaaacaaaaa tatctctgat gcgatcacac gtgtcgctcg gacaccatta cgtaagttag
    13021 gttatcaaga aagatttaca cgtccagtga gagaactaca agaacataac ttgacttgcc
    13081 cacatttgac ggcaacaatg gggattattt ttaattacta tgatcctgaa gatgaacaaa
    13141 gccgtcaatt gcatgaaatg aagatccatg aaaacttgga acaattgatt caagaagtca
    13201 caggaatcaa tgatccgaaa acaatcggga atatcaagca aaacgtgaac cgttatgcca
    13261 agcaagtcgc ttaaaatagg atacgaaaaa ggggaatgtg acgaaatttt tgtcacattc
    13321 ccctttttcg aataactagg ctgtttgtcc ttcaagatag ggcagatcca attctttacc
    13381 gtaacgttgt tctaaagcta ggcggatcaa acgagctgcc aggttctcat ttcttgcaag
    13441 gataggtcca tggaaataag aaccgaagac atttcggtaa atgacacctt cagattggtc
    13501 ttcaccatta tttccttgac cttgtaccac tttccccaaa ggtcgttcac cttcacctaa
    13561 gaaagtccga ccattgtggt tttcaaatcc ataataagtt tcattgaatt cttcgttatg
    13621 gataacgata tcaccgataa accggttatt ttcctgactt aacgtgtagt gatccagtgc
    13681 actgattcct tggatctttt ctccattagc tcccatgtag tagtgaccta gcaattggta
    13741 gccaccacaa atggctaaca tgacgccatc attttcgata tagttgatca aagaatcttt
    13801 ctttttctgg atgtcttttg aaatgattaa ttgctcaaag tcttgaccac cgccaaagaa
    13861 aaccaagtca tatttatcag catcaaaagg ttcatgtata ctaacgatct ccgtatggca
    13921 agaaaccccc attttttctg ctatatattt caacatcaaa aggtttccgt tatcaccata
    13981 tgtgttcatc aaatttccat aaaggtgggc gatattgagt tcataattag ccacggttca
    14041 ttcctccttt gataaatcct tgagcagcta gttctttacg aagctgcaat acagcagtgt
    14101 aagtagctaa aatatagaca tgctcagttg gcaattcttt gattttttcg attacttctg
    14161 gtaattcttt tgtttctgtc aatttatttt ctggaatccc ggcaactttt agacgtaaag
    14221 tcatatctgt atgacggtct cctccagaaa taacagctgg gatatccata tcggcaaagt
    14281 tttcaaaatt accatcccaa atccagctga catcgattcc gtctgcgtaa ttggcattta
    14341 ataaagccac taaagaaaat ggataaggag ctagaccaat catatcgatt acttgattga
    14401 tacctacagg atttttgaca agtactaatg tacatttttt cccattgata ttgatgactt
    14461 cttgtcggcc gaatactttc tcgtcatatc ctaaaccttg tttgatttta tcaggatcga
    14521 cattgaagta ctctgccact gcagtagctg ctaaagcatt gtagacatta tacataccgc
    14581 caacttcgat tccgtattca tgaccatcga tcacgaaatc tgctgacaca ttgtccatcc
    14641 gtaccatatc agttaatcga taatccaatt caggacgttt gaagtcacaa tttggacagt
    14701 aatatttccc taagtttgca taagtgatca ttttataatg caagatgtga tgacaatttg
    14761 gacataagac accgtctgta ttgtaatgag ccatttgttc acgatcttct tcatggtcaa
    14821 agccataata ttttctagga ttgactgttt cgatagaatt gaagattggt gaatcaccgt
    14881 tactgataat cgttgcattt ggtgactttg cggcaccgtc tacaatcatt ttataggtcg
    14941 tatagatttc tccataccga tccatttgat cacggaaaat atttgtaaat aagaacagtt
    15001 ctggtttcat atattctgtg actttgctca aacttgcttc atctatttct aggacagcaa
    15061 actttttctg tccttttttt ggttttgcct gcaagaaagt cgatacaatt ccctgtacca
    15121 tattcgcacc agtagggttg gttagaactt catcgaattg ctggcgcaaa atattgactg
    15181 ttaaagcggt agtcaatgtt ttaccgtttg ttccggtgac aacgacgact tggtagtctt
    15241 ttgccaaact atctagtata tgtggatcga ctttcagcgc tagtttacct ggtaaacttg
    15301 atccgccttt aaaaaaagtt tttaatgccc attgcgacgt ttttccaact gcaatcgcaa
    15361 aatgactgcg tattcccatt atgtaacctc caaaaacgat ttgctgacga ataaattcaa
    15421 ctaatcatac catatgttga aaaaaaggtt aaattgcttt tcttattctt aagaaaaggt
    15481 tacggctgaa agtgcatgaa atcggacaaa atcgcatgat ttaacaaaaa aacagcttga
    15541 aacaaaatga ttgtttcaag ctgctgtgat tttattattc cctcttacct atattcccat
    15601 tttaaccgat aataattttc tcgcttggat attcatagcc tagatctcgt gtttcttttg
    15661 gcacgaataa catcaatgta tatagcattc cgatccgccc aataaacatc agtgtagcaa
    15721 tcgtgatttt gcccacaaca gacaagtctc cggtaatccc taaagataaa ccagttgttc
    15781 caaacgcaga agttacttcg atgatgatcg agatcagcgt ttgttcttct gtagcagata
    15841 aaaaaacgat acaaaagaaa cacataccaa gagaaagcat aaagacaacg actgattttc
    15901 gcacatcatc ttgatcgatt ctccgtccaa aaatattgat gttatcttca cttttgagga
    15961 aggaatatag atacaaaccg atgattgcta cagtagttgt tcgaatcccg ccgcctacag
    16021 aactaggact gcatccgata aacatcagta aagaaaaaat gatcagtgtt gtgatttgaa
    16081 aatcacccaa atcgtgaatc tgcagaccag cattacgagt cgtaatcgaa taaaacatcg
    16141 aattgatcca tttgacactc atattggaat cttggaataa atggtccttt tccaatagat
    16201 aaatcaagac agttcccgaa acaaacaaga taacaaaagc taacacagct aatttggtaa
    16261 acaaggaaaa acgaaacgga agcttcgcat tggaacgttt gtataatagc cattcccggc
    16321 actccatcaa tacaggaaaa ccaattcctc cgacaaaaat caaaaacatg atcaggatca
    16381 agaaaaaata gtcatgtgca aagggcttga tggaatcccc agtgacgtca aacccagagt
    16441 tcgtgacagc cgatatcgcc tgataaaaac cgtaaaaaac ggcatcacgc caacgatcaa
    16501 aatagcctct gtaataaaaa taaatagaaa agaatgtccc aaaaagtaat tgaaaccaga
    16561 ttaaaatagc aaaagtgatc cgaatcagtc ggacgatacc agacaaacgc ggttgattca
    16621 tatccgtcat gatcagctgt cgctgtttca gtgtgatccg tcgtttagaa aaaatgacaa
    16681 aagcagtaga aatcatcatg atccccaaac caccaacttg aaataatatt tccagcagta
    16741 taataccgtt atcattgaac acagaattga tatcaaaagt cgatagtcca gtcacactca
    16801 ctgtactgat tgccatgaac agcatgtcca caaaagaaac atggctatct ggttcgcgaa
    16861 aaatcggcat ataaaataga acgagtgata agaccgtcat caatatataa taaaaaacga
    16921 tgatttggat cgatgagaaa tgattggcag caaacttctg tcctcgccgc tgcagccttc
    16981 gaaagaataa atcaacatgc acagtactat cctcctgaca atagtcgttt ctaccagtat
    17041 acaaggggaa ttaggaatac tcaaagaaat tatcaaacag ataacaatac agctttcgat
    17101 taaaatagaa atggcttata ataaggaaaa tcctagaaaa aagaaggagg aggaataaca
    17161 aattgattaa tgctcaacaa atcgtagaaa aaatgaaaaa tcaaaaaata aattatgata
    17221 cagttctgaa aaaaatgatc atgcaatggg agaaagaaga agtaaagcct aagatattaa
    17281 tacatacatg ctgtgctcct tgcagtacgc acacattgga attcatgtct caatatgcag
    17341 agatcacgtt atttttttca aattcgaata ttcatcctaa aagtgagtat ttgcgaagat
    17401 tacatgaaca aaaacgattt gtagaccaat ttaatgagaa aactgaccat catgttgcgc
    17461 taatcgttga tgaataccgt ccaaatgaat tcaccaaaat ggttttaaca aaccatcttg
    17521 aaaacgaaaa agaaggtggt gctcgctgca gtgcatgctt caatatgcga ttagatcttg
    17581 ttgcgcaaaa agcgcaagaa ctaggatacg attactttgg aagtgccctg accatctcgc
    17641 caaagaaaaa tgcagctttg atcaatcaga tcggaatgga tatccaaaag atttacggga
    17701 cacaatactt gccaagtgat ttcaagaaaa acaaaggcta tgaacgctct ttgcaaatgt
    17761 gcaaagagta tgatatttat cgccaatgtt attgtggttg cgtgttcgct gccaagcagc
    17821 aaggatgcga tctgaaagaa atcaatcggg aagcaaaagc ttacttaaaa acatcaaccg
    17881 tagtttttga ggaaaattaa agaaatcttt cggaaaaacg taagaaaaaa ataaagaatt
    17941 tatggtagaa ataaggtaga ctgtataatt tgtccgtagt aaagtaagga aacaagaata
    18001 aatttcaatg aaggaagaga taagatgcga aaagtagcac ctattttgaa gccaatcgct
    18061 gtattaacaa tctcgacgat tgtcgcgact actacaggta ttgtgaatag ttccagctac
    18121 cgtgcaccaa gttcaagttc tagtactgta gaagaaacaa caccaactac ttcagtctcg
    18181 acatctgaac caacaacaac ggaaagtttg aatgaaacca ctacgacaag tacatgggac
    18241 gatacaacaa ctagttcgtc gtatgatgag acatatacaa ctgacagctc aagcgaaaca
    18301 agtaatacgg taccagatgg cactccatcg gattcaacca atccaagtac aagtccggat
    18361 acaagtgcta gctccgaaac gataccaagc agtacgactg tagatgataa cacgcaaaat
    18421 gatgatgcag cacgtacagc acagcaaaac caagattcag gaaataccca aacgtataac
    18481 cagcaagcag gtgattctca atgacatttt tactagacct tatcaacggg gtgcataaat
    18541 tccttggcta tttagacatc agtcctaaat atcttaaccg tggatatacg attttaagtg
    18601 tgattcccac gctttattta ttgagaattg tttatggact ttggcaaaac caaaactatc
    18661 ttcaattttt cttatatgga cttgcatttc tagtgcttgt ttattttact gttttaaatg
    18721 tattttatta ctttttagat aaaaacacga aagccgatgt cactcagctt tttgtgaagt
    18781 atttacctga tgaagcgttc aacatccaga cagaagaatc gatagataat ggaaattcga
    18841 tcgataaagt gaatacacaa gaggtcatgg tttcttatga cgaagattat caattgaaat
    18901 tagccgagaa tatgcggtat ttgattggaa atggtgagat caaaacaaat gaactcggtc
    18961 gcatggatgg atttctggtc gatagaaata cattgtatcc ttattactat gtcaagaaaa
    19021 caggagagaa agagtatgtt ctaaatattg gacgaagcta ctcggacatg gaaaaagtag
    19081 ggaccattcg acttgactca acagaagaca cattggaacc tgtcggattg ttcatcgtcg
    19141 gcggtgattt tgtcaaagac gggttacgct atcatgagcc ttatcgtctg aaattgattg
    19201 caaaaaaggc acagtcgcag gaagaaccag tggtttatag tcgtagccaa agaagaagac
    19261 attcataatg tgatgaaacg ccgtgtatca gtggttgcga taaaaacgtt tattcggaat
    19321 aagggggatg tgacacgtct tttgtcacgt tcctttttta tataacgaga aagataagac
    19381 gaacacatca cttattcttt cctttcattt ataaacattg tagaataaag aaagtacaac
    19441 gaagtattgt gaaaaaacgt aataaataac gaggaaaata caagtaggag gtaagctgtg
    19501 aaagaatttt tgaaaaattg ggggattttg atccttgtat tagcggctat tttattagct
    19561 agagtgtacg tgtttacacc agttactgta aacgggcatt cgatggaccc tacattaagt
    19621 gatggacaac gattgatttc atctaagatc tcaaactatg aacgaatgga tattattact
    19681 acaaaggaac cgggggatga agaacggatg attgttaaac ggatcatcgg tatgcctgga
    19741 gatacagtca agatggaaaa tgaccagttg accattaatg gcaaaaagta tgatgaacct
    19801 tatctggatg agttcaaaaa agaattttca gaagataagt tacaaggaga atatgcttat
    19861 agctcaggat tccaagcaca agcagaaagt tcatccacct ttacgagtga ctttgaatat
    19921 actgtgccaa aaggaaagta tcttgttcta ggcgataacc gcttgatttc aaaagacagc
    19981 cgaatgtttg ggttagtcga caaagatatg atccaaggaa aagttgtttt ccgttattgg
    20041 cctctttcag aaattaaaat catgtgatga aaaaataaaa agaagctgtg acatgttttt
    20101 tgtcacagct tctttttccg aaaattcctt cttatttctt ggagttgctc actttttttg
    20161 caatctcatt ttaagctttt tggctgatgg ataagaaaag cgaagcgttt ttgttcataa
    20221 atagcttttc cccacgatgg aaggtatgac tagtagcaga gacaaagccc gttttttcca
    20281 atcgattatt caattcttct tggctaaagc cattatggac tttcggatga ctaatttgtt
    20341 cattcttgtc aaagtctacg atgatcaatt gaccgccagg agctaaaatt tcataaagtt
    20401 ttgtaagaat attctccgta tcaggaatgt gtaaaagtac aagtgataga aggatgagat
    20461 tagcttggac agcaggaaat tcgacagaag catcagcgtg gatcgttcgg acatttttca
    20521 gatctgctgc ttggatcttt tcttctgcca ttttcagcat agtttctgaa gcatcggcaa
    20581 tgatcagttc tttgaatctt tccgcaagcg gtaaactaac aagcccagtt ccgcctccgt
    20641 aatccagcag gactttttgg tggctgtcgc gcggtagata agtagttagt tcttcgcgaa
    20701 taatcttggc taatgcttga cggtcagggg aatcataatg gttagcgatg gaatcaaaaa
    20761 tattttttgt catcaaatag ctccttacgt aaaactttga aattttaact tattatagca
    20821 cgtgaaaaga aagaaagcat gctatactca attcaaaaag ggagaatcta gaaagaatat
    20881 gccgatatcg tttgtaaaag atagagagga aaaaggaaag tgtgtccgag aaatattact
    20941 agacttgcct gagtggtttg ggcttcctga atcaacggaa aaatatatcg aggaatcaag
    21001 taaactacct ttatggtgtg aaaaaagaaa agaagaatat ttaggcttta tcactctttc
    21061 acagacaagt gaagatactg ccgaaatcta ttctattgta tgggaataaa aaaagactat
    21121 catcaccaag gattaggaac aaaacttttt aaagaagcag aaggttacgc agcaaaacat
    21181 tacaaatatt tgcaagtgaa gactgtagac gaggggcact actctatata tgatcaaact
    21241 atttgtttct acgaatcatt aggattttca aggttggaag tttttccaaa tttatgggat
    21301 gaatggaacc catgtttagt tcttgtcaaa aaattggaac aaaagtgagc aatagattta
    21361 atactaatct gtgcttgatg aaaattctca ctgtaaaaaa tgctgaaaat caagtataat
    21421 accataggaa caaactggaa ggtgaaaaag agcatggcac aactattttt taagtatggc
    21481 gcaatgaata gcggcaagac gatcgagatc ctaaaagtcg cacataatta tgaagaacaa
    21541 aataagccag ttgtcttaat gacaagcggt attgatacaa gagatggttt aggcgttgtt
    21601 tcaagccgaa tcggactgaa acgtaatgcg atgccgatat ttgaagaaac agacgtattt
    21661 gacgtaattc agaaaatgga aagcaaaccc tattgtgtgc tgatcgatga agcgcaattc
    21721 ttaaaaaaga aacatgtcat tgcttttacg agaattgtgg acgaattgga tattccggtt
    21781 atggcatttg gtttgaaaaa tgattttcga aacgagttat ttgaaggatc aaaatattta
    21841 ttgctttatg cagacaaaat cgaagaaatg aaaacaatct gttggttctg ccacaaaaaa
    21901 gcaatcatga atttacatta tattgatgga aaccctgttt atgaaggcga tcaagtgcaa
    21961 attggcggaa atgaagctta ttaccccgtt tgtcgaaaac attactttca cccatcaatg
    22021 attacagaag gagaataagc atgtacgatc aattacaagc aattgaagac cgttatgaag
    22081 agcttggaga acttttaagt gacccagaag tgatttctga tacaaagcgt tttatgcagc
    22141 tttcaaaaga agaagcaaac acgcgcgaaa cagtcgaagt ttatcgtcgt tataaagaag
    22201 tagtacaagg aatcaccgat acagaagaac tgcttggtga aaaactggat gatgaaatgg
    22261 ctgaactagc aaaagaagaa ttatctgaat taaaaaaaga aaaagaagtc ttagaagaaa
    22321 aaatcaagat cttgctttta ccaaaagatc caaatgacga taaaaatatc atcatggaaa
    22381 tccgtggagc agcaggcgga gacgaagcag cattattcgc tggcgatctt ttcaatatgt
    22441 accaaaagta tgctgaagca caaggctgga aaacagaagt gatggaagct aacgttaccg
    22501 gaatcggtgg atataaagaa gtgatcatga tgatcaccgg agacaacgta tattcgaaat
    22561 taaaatatga aagtggtgcg caccgcgtcc agcgtgttcc ttcaactgaa tcgcaagggc
    22621 gtatccatac ttccaccgca acagttgtcg tgatgccaga agctgaagaa gtagagatcg
    22681 atattgaaga caaagatatc cgtacagata tctatcatgc ttcaggtgct ggcggacagc
    22741 acgtcaataa aacagcatct gctgtacgtt tgactcactt accaacaggg atcgttgttg
    22801 ctatgcaaga tgaacgttct caaatcaaga accgtgaaaa agcaatgaaa atcttgcgtg
    22861 ctcgtgtgta cgataagatc cagcaagaag cacaaagcga gtatgatgcc aatcgaaaat
    22921 cagcagtcgg aactggggat cgttcagaac ggatccggac gtataatttc ccgcaaaatc
    22981 gtgtgactga tcatcgtatc ggattaacta tccaaaaatt agatcagatt ttagcaggga
    23041 aattagatga gatcgttgat gcattgatca tgtatgatca aacatcaaaa ctggaagcta
    23101 tgcaaaatgg gtaaaatgac ctatcgagaa gtcctgtcac gggcttcttc ttttttagag
    23161 gatcatggga aagaagcata tagtatccaa tttttatttt tggaacgaaa acaatggaaa
    23221 aaacttgatt ggctccttca tatgaacgaa gagatttcag aagaagaaca gcggttgatc
    23281 gaaaccgatc tgcgacttct gcttgcagat catccacctc agtatttgct aggatatgca
    23341 gatttttatg atcatcggtt aaaggtaact gaagcaacac tgatccctcg accagaaaca
    23401 gaggagttag tcgaatggtg tttagacgag acgcctggtg taccgttaga agtgatagat
    23461 attgggacag ggactggagc aattgctatt agtttgaaag cagcaagaaa aaattggcat
    23521 atatctgctg tggatctttc agaagaagca ttagaagtag cgaaagaaaa tgctcagaaa
    23581 gaaggaacga aaatcagttt ttatcatgga gatacattag gaccagtaat ggatcagcaa
    23641 tttgatgtga ttatttctaa tccgccgtac atcagtcgga atgaatggga actgatggat
    23701 gaaagtgtcc ggtcattcga acctaaaatg gccctttttg ctgagaacga tggattagct
    23761 atttatgaaa aaatagcagt tgaagcacca agcgtactaa aatcaaatgg aaagattttt
    23821 ttagaaatcg gatttcgcca aggtgaagca gtaaaaaaaa tatttcagca agcatttcca
    23881 gataaaaaag tggcgataaa aaaggatctt tttggcaatg aacgaatgat ccaagtttat
    23941 ggttgaagtt gtggatgaaa aattttttat ttgttttttt attataaaaa aacacttatt
    24001 tgacaaggat gtaaacgact ttttggttta tcaacaagtt tatccactat tgacaaatag
    24061 attatccaca aacagtggaa aacttgagga taaactcaga caaaataaga atgtatgaaa
    24121 aaggggttgt ggataaactg tggaaacgaa acgatatgat gaaacagaat tgcaagaggc
    24181 agccgaagca ctgaaagaag gagaacttgt tgcttttcct accgaaacag tatacggatt
    24241 gggcgccaac gctcttttac caaacgctgt caagaaagtg ttttctgtaa aagggagacc
    24301 gcaagataat ccattaatcg tccatgtcgc ctcttttgaa caagtaaaag agtatgtgga
    24361 caactttcat ccggcagcag agaagattgt gaagaacttc tggcctggac cattaacttt
    24421 gatatttaag atcaaaaaag acactttgcc ctcagttgtg acgggaggat tatccacagc
    24481 tgcatttcgt ataccggata acaaaaaaac actagaagta atcgaacttt ccggtgttcc
    24541 gcttgtcggt ccaagtgcaa atacgtcggg aaaaccaagt ccaacgactg cagatcatgt
    24601 atatcatgat ctacaaggaa aaattaccgg gattattgat gatggagcta cgcgaattgg
    24661 tgtagaatcc actgttcttg atttaagtga tccaacagcc atgcctatga ttttacgacc
    24721 aggtgcagta acgaaagaac aaatcgaagc agtcatcgaa tctcctgttg ctattgatca
    24781 gcatcttgta aaagaaaatg aaacaccaaa agcccctggg atgaaataca aacactactc
    24841 acccgataca cgtgttctga tggtcagaga tggcgattgg tcaactgcag ttcaatgggc
    24901 aaaaaataag aagatccgtg caggtgtcat agcaagcccc gaaattgcgg atcaagtgcg
    24961 gacagatact gcagctgttt atatgtataa cgacaactca gtagaagcgg cggctaaagg
    25021 attgtttgca ggtctaagag gattagatga accaacactt ggattagatt tgatttttgt
    25081 acaagtgtat ccagaaactg gattggggaa tgcttacatg aatcgcttga aaaaagcagc
    25141 aggacaaaat tattttgaaa aatgatcaat tggttattgt cgcattcttt tagtatgata
    25201 caatgctatc aagtaaatct tctatcagtg aacgaaaaac taagcgtaac taatcgtaat
    25261 agaagagata cgaatatttg gcaatttgtt tttgatggga aaaataaaat tgtaggaaaa
    25321 taaaattgta ggaaaataaa aaggagctgt tgtttgtggt agattacaaa acgtttgacc
    25381 ctgatctttg ggctgcgatc gccaaagaag aagaaagaca agaacataat ttggagctga
    25441 ttgcctctga aaactttgtc tccgaagcag tgatggctgc acaaggaagt atcttgacaa
    25501 ataaatacgc agaaggttat ccagggcatc gctattatgg tgggtgtgaa tttgtcgata
    25561 tcgttgaaaa tttagcgatt gaccgtgcaa aagaattatt cggagcgaaa tttgcgaacg
    25621 tccagcctca ctccggctct caagccaaca cggctgctta tctcgctttg gtagaaccag
    25681 gggacacgat cttaggaatg gatctttccg caggcggaca tctaacacat ggatcaccag
    25741 tcaacttcag tggcaaaacc tatcactttg ttgcttacgg tgttgatccg acaacagaag
    25801 ttattgatta taatgtggta cgtattttag ctagaaaaca tcaaccaaaa ttgatcgtag
    25861 caggtgccag tgcttacgga cgaacgatcg actttgcgaa attcagagaa atcgcagatg
    25921 aagtaggcgc aaaactgatg gtagatatgg cacatatcgc aggattagta gcagcaggac
    25981 ttcatcctaa tccagttcct tatgcagata tcacaacgac taccactcat aaaacattgc
    26041 gtggccctcg aggcggcatg attttgacaa acgatgaagc attagcaaaa aaaataaata
    26101 gtgcggtatt tcctggtatt caaggcggcc ctctagagca tgtgattgcg ggtaaagcag
    26161 tagcattcaa agaagcatta gatcctgcat ttaaagaata tagtgaacaa atcatcgcca
    26221 atgcaaaagc aatggtcaaa gttttcaatc aagcaattgg aaccagagtc atttcagggg
    26281 cgacagataa tcatctgatg ttgatcgatg ttcgcgagtt aggtataaat ggaaaagaag
    26341 cagagagcat tttggacagt gtgaatatca ctgtaaataa aaactcgatt ccttttgaaa
    26401 cactaagtcc attcaaaaca agcggtattc gaatcggcac gccagcaatc actactcgcg
    26461 ggttcaaaga agaagatgct gtaaaagtgg ctgaactagt tgtcaaagca ttacaagcaa
    26521 aagatgataa cgctcaacta gacgaagtca aaacaggtgt acgcgaatta actgaaaaat
    26581 ttccgttgca taaaaaataa aaatttaaat tccattagta aacagaaaag ttcaatgttg
    26641 ggcttttctg tttatttttt gggaaaacgg attctttgac aatatcggtg atgctctcta
    26701 gtatatgagg tgtaatttta gtcttcacac taaatctcag ggaggaaaag tcatgactga
    26761 tcgtatctcg ttagaaaagg aagcagtagc attcagtgat gcaaatgcgc ctcatccgcg
    26821 tatctatgaa ctagcaccgg aagaaggaag agttttacta gaagaagtac aagaatcacc
    26881 tgtgaacaaa tattccgtcg atattgaaga cttgatggtg gatactggcg aatggggaaa
    26941 actcaatatt cgtctcgtac gaccagaagg gaatatggat aaattaccag ttatttttta
    27001 tattcatgga gcaggctggg tttttggcag tgctcaaacc catgataaat tgatcagaga
    27061 acttgcggtt cgtacgaatt ccgtcgttgt ctttccagaa tatagtcgat caccagaagc
    27121 aaaatatcca acagcaattg aacaaaatta tgctgtgttg caacagctga ataaattagc
    27181 caagtcaaaa aatctggatc tcgagaatct aatcgttgca ggagattcag taggtggtaa
    27241 catggctaca gtcatgacga tcttaacaaa agaacgaaag ggcctcccaa tatccaagca
    27301 attgctgtat tatccagtca caaacgctga ttttgataca gattcctatc atgaattcgg
    27361 agaaaactat tttttgacaa gagaaggaat gatgtggttt tgggaccaat atacgacgaa
    27421 tgaagaagag cgtgctgaaa tcacagcttc gcctttgaga gcaaatataa atgaactaaa
    27481 tgatcttcct tcagcaatga ttttaacggg agaagcggat gtattaagag atgaaggtga
    27541 ggcttatgcg cgcaaacttc gtgatgcagg ggttcctgtt acacaagtac gcttccaagg
    27601 aatcatccat gattttgtca tggtaaatgc tatggatcag acaaaggcaa cgcgtgcagc
    27661 aatggcatta tctacttctt ggatcaagaa aaaagaataa gctttgcttg tccgcaggaa
    27721 aacttctttt caaaaacgga ttttcttagg aaaaatggcg agtttgacta gtcaatcact
    27781 tgattttgtt ttacaattaa aaagaaacga cagaacaaag gagagcttaa aaaatgggca
    27841 aatttcaagt gatcgatcat ccattgattc aacacaaact aactattatt cgggacaaaa
    27901 actgcggaac aaaggttttt cgtgaagtag tcgatgaaat cgctatgttg atggcatatg
    27961 aagtatcacg ggatatgcca ttggaagaca tcgtgatcga aacaccgatc actgaaacaa
    28021 cacaaaaaac gttgtctggt aaaaaagtag cgattattcc aatcttgcgc gcaggtattg
    28081 gaatggttga cggtatcttg gaattgattc cagctgctaa agtgggacat atcggtcttt
    28141 atcgagatga agaaacattg gaaccacatg aatatttcgt caaacttcca gaagacattg
    28201 atgcacgtca gttgtttgta gtagatccaa tgttggcaac aggcggatca gcaatcatgg
    28261 caatcgatgc attgaaagaa cgtggcgcgt cgaacattaa atttgtttgt ttggtagcag
    28321 cacctgaggg agtaaaagct ttgcaagaag cgcatcctga tattgacatc tatacagctt
    28381 ctctagatga aaaattgaat gaacatggtt atatcgttcc tggactaggg gatgcgggtg
    28441 accgtttgtt tggtacaaaa taagtaaata cgaaaaaggg tgtgacacaa cttttgtcac
    28501 atcctttttt ggtcattttt aacgtttgat gcagaacagc tttttcacag ctttcgtttg
    28561 catataaaaa aaccatccca aaaatgcaga gatggtcaaa ttcaaatctt ttttagttct
    28621 ttgtagttaa cgattactac acccttactt tgcgtcatca agttcgcatt ttctgcagtt
    28681 tcatcaatct caacaacagc ggaatttttc aattgctttg aaatcgttcc agtttgcgac
    28741 ttgccgtgaa ttgtgaacat tacgtgagta ttgatcttga atttttcacc aatttccgat
    28801 ggtacgatag ttgtatcaaa ttttccaaaa gttgccattt tcataaaacc tgcctttcac
    28861 atcaattata ccacgtttta tgaaaaatat catgaaatta aactaatttt ccatcggact
    28921 ctttacaatc agccaaatag agtatataat ttcttttgga taaggccagc ttagctcagt
    28981 tggtagagca acgcactcgt aacgcgtagg tcgtaggttc gatccctata gctggcatta
    29041 aaagagaaga cagatatatc aaggattttt aatccattga tacatctgtc tttttgttta
    29101 aaggaaataa agtatgcttt cttagcaata gagcatgtat tatttctata aaaatttagg
    29161 agaataaaac gactagcaat atagctgtga aatcaaatat cacatgaact gcccaacttg
    29221 taatgatcga gttgctttta atggcagctt ggttgaataa caatcttgcc accccttgta
    29281 tcaaaaggat gtgtgctaca gtgtgtaaaa tatttccatt atcataagta ctgtaatgga
    29341 taaatccaaa gatgattgct gacaagaaac tagcgacagg aatgctgaac ttactagaaa
    29401 aaatagcgag aaaatacact gagaacaatt cttctccaag tatcatgata ggcaaaataa
    29461 taaataataa cgggctgaaa gcctcattta ttggattgcc tgttaaaccc catttcaaaa
    29521 tttgttgcaa aaataccgag actgcggcac tgattactac attgataaaa aaatatttgg
    29581 ctatattttt gacaggagcg acaggtttcg agaacatttt tttcgtatct tttttaccaa
    29641 aaacaagtgt aaatgctata aatccagtga tagttaaaga aaaaatgcta ataatggatg
    29701 gcgcaaatag caaccctaac aaaccgagta caacgacaat agtgcccaat atcccttttt
    29761 taagttctat tttttttcct aaaatgttat tcatgataat aactcctact attcagtttt
    29821 tgaagataga gtcagtatac atgaagagtt aaaataggca atgttttttt atggatattt
    29881 gtattgctaa aaatttatct tatatattca ttttgattat actactttta tttgtaaaaa
    29941 ttttctagca aaaccaagtg cttgcaactg attaagcgta caatttttta gatgttccga
    30001 gcgtacttca atcatttcaa aggagttgct acttaaatcg atatttttta aatcagtatc
    30061 aaaaaagcta gcattttcta aatcattagt agaaaacatt attttagtga gggaacagtc
    30121 tacaaaatct gcgcttgata agacagagtg ctcaaaggta ctttctttta tgtttgaacc
    30181 agataaattt acatagtcca ttttacaatt ctcgaataac gtgttcccaa tataactttc
    30241 catcaattta gtacctgtta atttacaatt gacaaatttc acgcgatgca acatgctttt
    30301 tgtcaatata cagcctgaaa aatcacagtt ttcgaatata cagtcggtaa tctccattct
    30361 ttgaaaatca ttggaagcaa aaaatgcata cttgaaaata gatttgtaaa taattggatg
    30421 gcagattatt tggttttcga tgacctcttt ttgtgaaagg atattataca gttcaaaatc
    30481 ttcgttttca tagatatgaa aaaaggatcc tttattcaag cttgcttcat taactttagg
    30541 aaaaatcata tttaattacc tccattttca taaagtcata ttaacaaaag ctaaaccaac
    30601 ttacattagc agaaaatgag ataggttttc gcctttttcg ataacgatag tgtcgctatc
    30661 tcttgaaacg ttcttagaat tgccctgaga gacacaaatt aggcgtaatt ctaataaaaa
    30721 tcttagaata aaaattttta ctgatttaat ttagaatgtt tttaaaataa aaatcgttgc
    30781 cataacagtg tattgaaagg ttttaacaat ccagtaatga tttaaaaaaa tctagatgta
    30841 gcgtatactt tgtttataga atgtagtggg aagaaatata tttttgggag gaaatcgtga
    30901 tgtctaaaag tgaagaaata gaaaacatgg tactaaaatt atatgatctc gttttaaatc
    30961 cagagatcaa agaaaaggaa cgtatacttt tgatagacgc aaagacaggc ttagaaaaag
    31021 gtcagtatta tcctaaagtc ataaataatt tggaacgtag tttacgtccg ttagcaatca
    31081 ggggagaatt gtctaaacca gtatcaccgt tttatatgga gatatcaaca ataggaaaat
    31141 ttgaaaaaga attaggtcga ggaatggctt cggcaccgat tacttttggg catttataaa
    31201 aacgagttat tcatctcaat gaattaaaaa gtatagtcaa tctcataatg caggctaggt
    31261 tcatttattt gaacagagtc tgtatttttt tattctaaat aaagaaacag atgtttcttt
    31321 atattgtatt ttatccttta attaacacaa aaacagctag tataaactaa taatgttaat
    31381 taaaagtgta ttttatgaaa ctatcgttat ttattaatgt tgcatttttg taagttaaaa
    31441 attggaaata tagattgaaa aaatgaaagc aataagtaaa ataaaatgaa tatatgcgaa
    31501 aaaataattt acattaggaa aaaccttgta aaaacagttt tttggcatat ttatttttta
    31561 taaatatttg taaaataact atcaattttt tagttaaaag attggaaatg agtgggggag
    31621 gaattgaaga aaggattttt gagagatgat atagtaggtt ttatttttag ttaaaatagg
    31681 ggagatagaa aaaatgaaaa agtgtagaaa tattatttta tcaatgttat ttattattac
    31741 taatataaca tcactgattc ctgttcatgt ctatgcggat gcaggcagag atatcagcag
    31801 taatgtcact tcgttgaccg tggacccaac gaatattaca gatggaggaa acataaaagt
    31861 aaaattctcg tttgacgaaa aaaaacaaaa tatccaacca ggtgattatc tttggatcaa
    31921 ttggccaagt gaaggaaata ttcgcggtga aggattccaa aaagaaatcc cattaatgat
    31981 tgaaaataaa aatgttggaa ctttaacggt cagaaaagat tctgcgcagg ttgtgtttaa
    32041 tgaaaatatt aaaaacctag actcagtaga aggttggggg caatttgaga tacaggccag
    32101 aaacgtaacc gataccggtg aagaaaatac gggaccattc accgtgacga gcggtgataa
    32161 aacagctact gtaaatgtga caaagccagc ttctggttct tcttctagcg ttttttatta
    32221 taaaacagga gacatgctac ctgaagatac taagcacatt cgatggtttt tgaatattaa
    32281 caataacggc acttatgttg aacaaccagt taaaatcagt gatgaaatcc aaagtggaca
    32341 aagattagat ccaagtacgt ttgaaattaa tcaaatacac ttaggtgaac agaaggttta
    32401 tagaggagaa gagggaatcc aacaattttt acaagatttc cccagcgcta catttaattt
    32461 ttcagtaact gataattaca ttgaaataac tataccaaaa aactttgtca atcttaggaa
    32521 aataatggtg agttataaga cgatcataga aaacccagaa caaataaatt ttgagaatca
    32581 ttcggaagct tggtttaaag aatttaataa acctgctgtt gatggagaaa gtttcaatca
    32641 tacagttaaa aatatttcag cttctggtgg agtcaacggt acagttagag gcgaattgaa
    32701 gattttcaaa tatatcaatg acacagagat tggtatccca aatgtgactt tcgaattaag
    32761 acgagcagat gaacagccta ttcaaggaca gtctagtatc ctgttgactt cgaatgaaca
    32821 gggagaagct agtatcaaag gcctgcaagt aggagactat gttgtaaaag aaaaagaagc
    32881 acccaattgg attgattttg atccactaag ttcaaatgaa ctcaaattct ccataaacga
    32941 aaatgataca gagggagtca gtttacctat ttataacaag aaaaaggtta cgaacatcac
    33001 agcaactaaa atttggaacg gtggaaccac tccaagaccg agtatttatt ttaaattatt
    33061 cagagcaagt acaaacaatt gggaaccagt tcctgatgca gaaacaaaac gattagacaa
    33121 tggaataact tcagtgactt gggaagatat ccaacagtat gatgatagtg gaaacgaata
    33181 tacgtttaaa gtgcaagaag tagatcaaaa cggaaatgat tatgtccctt caggttatca
    33241 aaaaattgaa aacgggctag tcgttacaaa tgagaataaa gaagtcattt cagtctcagg
    33301 acaaaaaaca tgggaagaca atgagaacca agacggcaaa cgaccgacga cgatcacagt
    33361 aaatctatta gccgacggtc aaccgatcca acacaaagaa gtaagtgaaa aagatgattg
    33421 gcgctatcgt ttcacaaatc tgccaaaata cagagacggg caagaaatca tctatactgt
    33481 aacggaagac aacgtgcccg aatacagtac gacgattgac gggtataaca tcaaaaacag
    33541 ttatacaccg gaaaaaacaa atatatctat accaggtagc catataacac cgtggaaaaa
    33601 ttttccagag aagacagaga gagagaaaat tagaaatcta ttctctcaaa aattgcaaat
    33661 atttgctcat acaggagaat ccagcgaaca aagaagcaat tatattagta agagagctgt
    33721 acctaaacag ataacaaata aatcaaaaag cattcttcct aaaacaagta gtaaaaaatc
    33781 tagttttgct gtaatcattg gtttattgat agtaactatc tgtgctggga tattcttaca
    33841 aaaatataaa aaagtttagt tagaatataa tattttttgt taaatatgac tgaaatcaaa
    33901 agaataaaat tccgatttat aatcgaaaaa agaagcattt ttatatatgc ttcttttttc
    33961 gtagaatcaa taaatatgga tttggctaac tatggaagaa tactcgtatt agttttcagc
    34021 gttcatacta gttgttacat tgtttgattg gccaaaagaa tttctgatat attttgtgct
    34081 aaataaagaa aaagacgctt gaattgggaa ataagaaaac tactctatca ttacaaattt
    34141 tcataaactg gcagatgttc taagtaaaca agtatctttt caaagtcgga aaaatccata
    34201 atcaacgtag tggtattgat atttggatga aagcctacgg tatcttgacg atcaatagca
    34261 gcatcgatca cgacttggat ttttttctct ttgtcgtgca tcaatgctaa tggagtcact
    34321 gtacctgctg gaacgcctag gaggtcagga agctgttctt cagaaacaaa agataagcgc
    34381 ttttctttta attgttcagc tagttgtttt aaatcggcgt gcttttcatc aggcaagatg
    34441 acaagataga tttgttttcc ttttcttgat ttcaataata gattttttac ttgcggacca
    34501 ggtagggaaa aagggacatt tttgactgac gtaatcgcag gatgatcgac tttttgaaaa
    34561 gagataccca gtttttttag tagttcataa gcttcttgtt cggttgcacg actcatcgcg
    34621 catcaccctc ctttttttat tagtgtatca taaaaaagag ttgacaaatg aaaaataatc
    34681 atgtaaatta cacgtaaagt taaaacaaat gacatcgaaa agaagagtag ccgttaggtg
    34741 tttttagaga gtctctggtt ggtggaaaga ggcagcagtt aaccgtgaaa cacatcttgg
    34801 agtcgatttt ctgaagcgta tagtaggaaa atccggggag cccgttacag ctgcggtcgt
    34861 tgctagatga ccagataagg ctggcttttc cgtgaggagt cggtaaaaaa aggtggaacc
    34921 acgtgattaa cgtcctttga tcttcggatc aaaggacttt ttgttttcat ctgaacggca
    34981 acgactgtgt gaggtttttt ctgcaaggaa aaaataaaca gaggtggaac cacgtataat
    35041 acgtcctctt ggcatttgcc aagaggattt ttttatttta aaggaggaaa agaagatgga
    35101 gtatttgatt gaagttatgc cgcaattatt agtaggagca ctcacaacat tgaaattatt
    35161 tttatttacc ttgattggct cattaccatt agggattgtt ttagcattag gattgtcttt
    35221 gcattttaag ccgctacgct acttgcttca aacatatgta tgggttatgc ggggaacacc
    35281 gctgttgttg caactgattt ttatttttta tgggttgccg acgattggga tcgtttttga
    35341 tcgtttcgaa gcagcactca ttgcctttat cttaaactat gcagcttatt ttgcagagat
    35401 ctttcgtgga gggatacaat cgattcctca aggtcaatat gaagcagcgc aagttttgca
    35461 attaagtccc tttcaaacgg tgacgaaaat cgtcatccca caagtgacaa agattgtttt
    35521 accttctgta gggaatgaag ttatcaactt ggtcaaagat tcttccttga tctatatatt
    35581 aggtttaggt gacgtaatgc gtgctgggaa aatcgcgatg gaacgcgacg cgactttact
    35641 gcctttgcta ggcgtggcaa tcatctatct tacattgact ggtattctaa caatcgtaat
    35701 gaaacaagtt gaaggaaaat taaattatta ccgctaactg ataggaggaa gaaatatgat
    35761 tgaattgaag aaagtgaaca aagcatttgg tgaaaaaaaa ataatcaaag atttgaatct
    35821 aatcattcca gatgggaaaa cattagctat cgtaggtcct tccggtggcg gtaaaaccac
    35881 gcttttacgt atcttggctg gcttagaaag ttctgacagc ggagaatttt atttagacgg
    35941 tgtaccgttc aacccattcg agcttaaaat gaaagaacaa gttgtaggag tcgtattcca
    36001 agacttccag ctatttccac atctgaatat ttttgaaaac attaccttag caccaaaaat
    36061 ggtattgaaa cagacaaaag aagaatacac caaaaaagca gaagaattag cggcttcatt
    36121 agggattagt gatttattga atatctatcc ttatcagctt tctggcggac aaaaacagcg
    36181 ggtagcgatt gccagagcat tggctatgaa tccacgggta ttggcttatg atgaaccaac
    36241 aagtgcttta gatcctgaat tacgccagca agtcgagcgt ttgatcctat cattgaaaga
    36301 agatggggta acccaaatta ttgtcaccca tgatttagta tttgcagaaa atgtcggtga
    36361 tcaattacta aaagtttccc caattcatta agaaaggaga agatagagat gaaaaaaacc
    36421 agttttctat tcgctttgat cgcaggtctt cttctttttg caggctgttc gaacaaaaaa
    36481 acttcagcag ataattgggc gactatcaac gaagagaaaa aaatcgttat aggtttagac
    36541 gatacatttg ttcctatggg atttagagat aaagacggga agctcacagg atttgatatt
    36601 gatttagcca aagcagtctt tgaacaatat gggattacgg tagactttca gcccattgac
    36661 tggtcaatga aggaatttga actgaacaat ggaacgatcg atttgatatg gaacggctat
    36721 tccaaaacgc cggcaagaga aaagaaagtg caatttacaa aaccttatat ggaaaacgat
    36781 caagtgctga tcacacctaa agaatcagga atcacaaact ttggacaaat gaataataag
    36841 agattaggtg cgcaaaatgg gtcatctggt tatgatgtat ttacgaaaca accagaagta
    36901 ttaaaagaga tagtcaaaaa ccaagatgct gttttgtatg atagttttaa tgaagcattg
    36961 atcgatctga aaagcagacg ggtcgatggt ctgctgatgg ataaagtata cgcagactat
    37021 tatttgaaac aaagaaacga actagaagac ttcaacataa caaaaggttc ttatgagagt
    37081 gaggattttg cagttggtgc acgcaagtca gatagtacat tagtgaaaaa aatcaatgaa
    37141 gccctagatc aactagagaa aacaggtgaa ttccaaaaaa tatccgataa atggtttggc
    37201 gaagatgtta cgccgagaaa ttaacaaata ggggactgtg acaaaagacg tgtcacagtc
    37261 cctttttccg aataaacagt gttctcctgc caactccttg tgactcggag ctgaatggca
    37321 ggctcacaac ctcttggtaa acggtgttca aaagccagtt tttcggtatt aagccaaatt
    37381 tatgcaaaaa tgtagaaagc cattttcaca aaatttttct tactactcga aactaagcga
    37441 ctttttcaca acctccttta cataatttta ttttgttgtg gaaggggttt cgtgttattc
    37501 taaaagagga acgattgaag gttataggaa aggaagagat gaatggaaca caaagaactt
    37561 acctcatttc caaaagattt tctgtggggc tctgcttctg cagcgtatca agtagaagga
    37621 gcttggcaag aagatgggaa aggagaatca gtctgggatc gatttgtacg gatacctgga
    37681 aagacattta aaggaacgaa cggtgatttg gcagtagacc actatcatcg ttataaagaa
    37741 gatattgctt taatgaaaga acaaggtctg aaagcttacc gcttctctgt agcttggaca
    37801 cggatttttc ctaatggacg aggagaagtc aatcaagctg ggctcgcttt ttatgagaga
    37861 ttgatcgacg aattgattga aaacgatatt gaacctatgt tgactttata tcattgggat
    37921 cttccacaag cattgcaaga tgaatataat ggttgggaat cacgtcagat cattgaagat
    37981 ttcactcatt atgcagaaac attatttgag gcattccgcg ggaaagtcca ttactggatt
    38041 agtttgaatg aacaaaatat cttcacttca ttaggttatt tgttagcagc acatccgcca
    38101 ggtgtgacag acccgaaacg aatgtatgaa gttaaccata ttgctaattt agcaaatgca
    38161 tctgtcatca ataaatttca cgagttagaa atgcctggaa aaatcggacc aagctttgcg
    38221 tatacgccaa attatccaat tgacagtaat cctgaaaatg ttctggctgc tgaaaatgca
    38281 gaagacctga tggccaatta ttggatggat gtctatatgt ggggaaaata tccgattgct
    38341 gccatgaggt tcttagaaga aaaaggatgg gcaccaacga ttgaagctgg cgatgcagaa
    38401 ttgctagaat ctgctaaacc agattttctt gggatcaatt actatcaaac ggcgacgaat
    38461 gcattcaatc cattaaacgg agttggtgct ggaaaaatga atacgacagg aaaaaaaagt
    38521 tcatcagaag aaactggagt tcctggaatg tataaaaaag ttgagaatcc atttgtcgaa
    38581 cgaacaaatt gggactggga gattgaccca gaaggattaa ggatcggact gcgtcgtatc
    38641 acaagccgtt accgcatgcc ggtactgatt acggaaaatg gcttaggaga gtatgacaag
    38701 ttgacagaag ataaacaaat ccatgacgac tatcgaatca attacttaca aagccacgtc
    38761 aaagccatca aagaagcaat ttcggatgga gcagaagtcc taggctattg cacctggtct
    38821 tatacagatt tgcttagctg gctgaacggt tatcaaaagc gatatggatt tgtatatgtt
    38881 gatcaagacg aaacacaaga aggatctttg gaacgatata agaaagacag ttattactgg
    38941 taccaaaaac tgattgaaga aaatggagag aacctttagt tcacatactt aaaacaagaa
    39001 ggtacggctg gatatggccg tgccttttct tgataaaatc atttagaaat taagaaaaac
    39061 tgtaaaataa gctgaaaaat gaaagaaagc gtcagttctt tcaaacaaaa ctttagttcc
    39121 cttacttttt tttgtataat gaaacttgat gaaatgaggg ataataaatg gcacaaaaga
    39181 aacggcctac taaaaaaagg aaaaagacga aaaaaacgaa aaagcaaaaa cagcagcagg
    39241 aacaaatgct gacgattggt gttgggtttg ccttgatttt atttgctgtc ttcggctttt
    39301 taaaattagg ttttttagga atattgattg caaacggctt tcggatcatt gcaggaaata
    39361 cttaccaaat cctctgtctt ttattagccg tattaggatt ttggattgtc attaagaata
    39421 cagagttttc aattggtaaa aaccgacgct ggtttggcgg catactcttt tatttcggta
    39481 tcttattatt gttacatgcc catttatttg gcaaactcca tactggggaa ccaaatatca
    39541 tggggacgac atgggatttg ttagccagtg atataaaaca aagtcaagta gacaataacg
    39601 ttggtggtgg gatgattgga gcaatccttt atcattttac ttacttcttg attgcacagc
    39661 ctggaagtta tttagcagca gtgctattac tggcaggagg agcattcctg ttcagtaatc
    39721 tggaaggcta tcagctgtta aatggtatcc aatcaattgg agaacgagta caggaattat
    39781 tggaaggtga tcctgccaag caagctcgaa agcaagcggc aaaggaagag agaatgaaac
    39841 agcgcgcaga agcgaaagaa gcaaggcgct tagctgcaaa agaagctgca gaatatgaga
    39901 agaaaaaagc ggtgagccag caaagggaaa atactgctga tgaatggcag gaaccagaaa
    39961 atacagagcc ggagcagcta agttttgttc caatcgacag ttttcaagaa aatatccatc
    40021 ctgcgaatct agagaaacca gtaccagata caccaaaaca gaccaataca gcagaaggtt
    40081 tttcagatga gttgccagag gatgacggta cctcattaga atttgagatt gaagcagaac
    40141 aggaaaatca agactatgaa ttaccgacag ttgatttgct tgattctata ccaactgtgg
    40201 atcaaagtga tgagtataaa aaaattgaaa aaaatatcgg cgtattagaa caaactttcc
    40261 aaagtttcgg tgtcgatgcc aaggtcgtca aagccagctt aggaccatcc gtcacaaaat
    40321 tcgaagtcca gccggctgta ggggtaaaag taagtaaaat tgtgaactta acagatgata
    40381 tcgcgcttgc tttagcggcg aaagatgtcc ggatggaagc accgattcca ggtaaatcac
    40441 tgattggtat tgaagtacca aatggaaaga tcagtatggt ttcctttaga gaaatcatcg
    40501 aagcacaacc aaaccaccca gataaattac tagaagtacc tttaggacgt gatgtttctg
    40561 gacgggtaca aacggctgat ctttcgaaga tgcctcactt actcgtggct ggttcgactg
    40621 gtagtgggaa gtcagtagca attaatggga ttatcacaag tatattaatg cgtgctaagc
    40681 cccatgaagt aaaactgatg atgatcgatc cgaaaatggt tgaattgaat atgtacaacg
    40741 gcatacctca tctgttgacg ccggtcgtga cgaaccctag aaaagcagcg caagccttac
    40801 aaaaagtagt acaagaaatg gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa
    40861 atatttctgg ttacaatgaa tttgttcaac agaaaaactt ggaaaacgga acgaaacatc
    40921 caaccttacc attcatcgta gtgatcgtag atgaattagc tgatttgatg atggtagcca
    40981 gcaatgaagt tgaagatgcg attattcgtt tagcgcaaat ggctcgggca gcggggattc
    41041 atatgatcct agctactcaa cgtccaagtg tggatgttat cacaggaatc atcaaagcaa
    41101 atgtaccttc cagaatggca tttgcggtat caagcggtac agattctcgg acgatcattg
    41161 attctaatgg ggcagaaaag ctcttagggc gaggagatat gctattcttg ccaatgggtg
    41221 agaataaacc gatccgtgtg caaggagcat tcatttctga ccacgaagta gaacgggtcg
    41281 ttcaatttgt tacagatcag caagaagctc attatgaaga gaaaatgatg ccgacagatg
    41341 aagttgaaac gacaggtgct ccagaacagc cacaagatga gctgtttgaa gaagcaaaag
    41401 cacttgtcgt tgaaatgcaa acggcaagta tttcccttct ccaaagaaga tttcggatcg
    41461 gttacaaccg agcagcacgt ttagtagatg aactggaagc tcatggagtt gttggcccgt
    41521 cagaaggaag caagcctcgg aaagtattca ttgagcagga agaaacatca gaaacgttgc
    41581 cggacgataa tgacatgtaa aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa
    41641 aaagacaagg catgatgata ccaaaagaaa aaatggtttt tttccatctt ttctaatacg
    41701 gtatgatgtc ttgtcttttt agtttttgtg agattaaagt tctattcgat ttatttgtga
    41761 agtattgcat taaggaaatg aatcatgtat agtatgtagc gaaactttga gaaaaagagg
    41821 gaaaatactt tggaaaaaca gtccatttat ggcttgacga atgaagaatt aatcaattgg
    41881 tttatagaaa acggcgagaa aaaattccga gctgcccaag tttgggaatg gttgtatcaa
    41941 aaacgtgtaa gtaatttcac agaaatgacg aatctatcga aacaattgat cgaaaaatta
    42001 tcggagcatt ttatcatcaa tcctctaaaa cagatggtcg tccaagaagc ttcggatggt
    42061 acagtaaaat atttgtttga actccctgat aaaaacatga ttgagactgt actgatgaga
    42121 caagaatatg gcttgtcagt ttgtgtgacg acacaagtag gatgtaatat cggctgtacg
    42181 ttttgtgcaa gcgggctgct caaaaagaac cgtgatctga ctgctggaga aattgttgca
    42241 cagatcatga tggtccaaca ttattttgat gagcgcaatc ttggcgaacg cgtttcacat
    42301 gtcgttgtaa tggggatcgg tgagccattt gataattacg acaatgtaat ggactttttg
    42361 catatcatca atgatgccaa aggattggca attggtgctc ggcacattac agtttccact
    42421 agtggattag cacacaaaat caaggaattc gctaataacg gcttgcaagt caatctggct
    42481 atttccttgc acgcgccgaa taatgaggtg cgaacatcga tcatgcggat caaccgaagt
    42541 ttcccaattg agaaattgat ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga
    42601 atcacgtttg aatatatcat gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa
    42661 ttagcagatc tattaaaaga taagaaaaaa ttagcatatg tcaacttgat tccatataat
    42721 ccagtcagtg aacatgatca atattctcgc agtccaaaag ctgatgtatt gagattttat
    42781 gatgtattga agaaaaacgg cgtaaactgt gtgatacgta aagaacatgg tacagatatt
    42841 gatgcagctt gcggacaatt gcgaagcaag caaatgaaaa aaacagttgc caaataatcg
    42901 tatcctactc gttttttcaa ttaccataaa aggagcagtt ttcttaatta aggaactgtt
    42961 caacttaaat aagagaaaag attctatagc gaaagctata aagctttttt tgacaagaaa
    43021 aaccctcatc aagcaaagaa atgtcctcaa tttgatgaca gcctgcttga tgggggtttt
    43081 agcaattatt taactgattt tcttatatcc ttgctggctt tcttgtgtag catgataagt
    43141 ttctacgtca agaatggcct gtttaaattt ttctcgggtg atttcataag gcacatgttt
    43201 aatatcattt gttgccatgg ctttatctaa gattgcttct aaatcggtcg tgacattgag
    43261 attcatgtcg gttaacgata ctggaagttg gttctttttc ataaacacat agattttatc
    43321 aaacaaatcg aactgctgat ccatcatcaa taaggtcagt acaccataac tgacagatgc
    43381 tccgtgaagg tatccctcca ttttttctag aacagtcgta ccgtaataga atgagtgtgc
    43441 catagcagaa ttatagttat tgttaactaa aacagaaacc aatccggtag taacaatgat
    43501 atccgaaacg acttgttcaa ttgcatatga gggacgatcg tcggcactat ctttcaatgc
    43561 ttgcgtacca taagtcaaga gacgatcaat gcacattttt ccgatttgga ttcctaatct
    43621 atccgtgtag cctagatcat cgccacgagc agaaaaagta gattcgactt ctttggataa
    43681 agcatcgcca atacctgccc ataagtattt atcaggtgct tcggcaataa ttgctgtatc
    43741 aatgaaggtg tgtacaggtg gttttgaagg aaagaagagt ccgtccatta cgccttcttc
    43801 gttatagatg acacataccg cagtgacggg cgaacagttc gaaccaatag tgggaaaggt
    43861 gaagactggt ttagctagtt tttcaccaat gacttttaca gtatcgcaag cacggccacc
    43921 accgactgca aacaggacgt ctgctttttg gacactttca tgctggatca actgttcaat
    43981 atttccataa gttgaattac ccccgtacca gagactggcg acaacctcta tttcctgtgt
    44041 caaagctact tttattttgt tttctgcctt tgaaagtgca gtcttccctc caatcagcac
    44101 tacttttgtc ccatattctt tgacgattcc atttgctttt tcatacgcat ctgttccaat
    44161 ggtataattt ggtaagaaaa cactttgact catattcatt tccttctttc ttcgttgaaa
    44221 cgggttaaaa ttttaaagag tgatcgatct gactgcggct gtagatggag tagaggtgaa
    44281 cctaagacag gataagtgat gaataaggtg gcatgaacac cttgaaatca tcaataagta
    44341 tcctaaaaac gaacaagtac aaaaacattg aaaacgacaa taatgaattt ttgttcctct
    44401 tagtatttct accgattccc tttgcttttt tgtaattatc taaaaattct aaaaattaag
    44461 attattatat gaaaacaggt tttatttgtc aattcataat tggttttttt taaagcaaaa
    44521 gataatctat atcatgatga acaaacagag ttttttcctc caattgatgg ctttcctgat
    44581 ctttcctatt ttgaataaag tgtttctgta taatttttta ttttataagt aagataaata
    44641 atgaaagaat agagatactg attggtagct aaagattttt gagcgagaac atttcgtttt
    44701 ttcaaaagga ctgttagaat aagcaagaac aagggggaag acgtatgata atcagtgaat
    44761 ttgaccgtaa taatccagta ttgaaagatc agctttctga tttactgaga ctgacttggc
    44821 cggaagaata tggagacagc tcggcagaag aagtagaaga aatgatgaat ccagaacgaa
    44881 tcgcggtagc agcggtagac caagatgagt tagtaggatt tattggtgca atccctcaat
    44941 acggtatcac aggttgggaa ttgcatccat tagttgtaga aagctcccga cgaaagaacc
    45001 aaataggtac tcgattagtc aattacttag aaaaagaagt agcttccaga ggaggaatca
    45061 cgatttattt aggtacggat gatttagacc atggaacaac gttaagtcaa acggacctgt
    45121 atgagcatac atttgataaa gtggcttcca tccagaacct tcgtgaacat ccgtatgaat
    45181 tctatgaaaa attaggttat aaaatcgtag gtgtcttacc aaatgcaaat ggctgggaca
    45241 aaccggatat ttggatggca aaaacgatta ttcctcgacc aaattctcaa taataaaaag
    45301 aggttgtgac agaagtaatc agcttcaaga aataagaagg aatttacgaa aattacttct
    45361 tgaatttttg tgaaattcca acttatttcc gaagaagcta cttttggaac accgtgtac
//
LOCUS       DBBGSP010000021        43680 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000021 DBBGSP010000000
VERSION     DBBGSP010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 43680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.021"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(105..629)
                     /locus_tag="ACIZE9_001318"
     CDS             complement(105..629)
                     /locus_tag="ACIZE9_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGC6093188.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="ACIZE9_001319"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="ACIZE9_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGC6093189.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="ACIZE9_001320"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="ACIZE9_001320"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGC6093190.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="ACIZE9_001321"
     CDS             complement(2351..3031)
                     /locus_tag="ACIZE9_001321"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGC6093191.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="ACIZE9_001322"
     CDS             3157..4026
                     /locus_tag="ACIZE9_001322"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6093192.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="ACIZE9_001323"
     CDS             4052..4567
                     /locus_tag="ACIZE9_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGC6093193.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5177)
                     /locus_tag="ACIZE9_001324"
     CDS             complement(4614..5177)
                     /locus_tag="ACIZE9_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6093194.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="ACIZE9_001325"
     CDS             complement(5232..5411)
                     /locus_tag="ACIZE9_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093195.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="ACIZE9_001326"
     CDS             complement(5488..5997)
                     /locus_tag="ACIZE9_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093196.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="ACIZE9_001327"
     CDS             complement(6093..6473)
                     /locus_tag="ACIZE9_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6093197.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /gene="pnuC"
                     /locus_tag="ACIZE9_001328"
     CDS             6803..7552
                     /gene="pnuC"
                     /locus_tag="ACIZE9_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGC6093198.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7736..9013)
                     /locus_tag="ACIZE9_001329"
     CDS             complement(7736..9013)
                     /locus_tag="ACIZE9_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093199.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="ACIZE9_001330"
     CDS             complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="ACIZE9_001330"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGC6093200.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9936..10880)
                     /locus_tag="ACIZE9_001331"
     CDS             complement(9936..10880)
                     /locus_tag="ACIZE9_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HGC6093201.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10882..11568)
                     /locus_tag="ACIZE9_001332"
     CDS             complement(10882..11568)
                     /locus_tag="ACIZE9_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HGC6093202.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            12042..12362
                     /locus_tag="ACIZE9_001333"
     CDS             12042..12362
                     /locus_tag="ACIZE9_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HGC6093203.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            12516..13421
                     /locus_tag="ACIZE9_001334"
     CDS             12516..13421
                     /locus_tag="ACIZE9_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093204.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            13418..14191
                     /locus_tag="ACIZE9_001335"
     CDS             13418..14191
                     /locus_tag="ACIZE9_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGC6093205.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(14372..15796)
                     /locus_tag="ACIZE9_001336"
     CDS             complement(14372..15796)
                     /locus_tag="ACIZE9_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HGC6093206.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            16007..16453
                     /gene="nrdI"
                     /locus_tag="ACIZE9_001337"
     CDS             16007..16453
                     /gene="nrdI"
                     /locus_tag="ACIZE9_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGC6093207.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(16518..18500)
                     /locus_tag="ACIZE9_001338"
     CDS             complement(16518..18500)
                     /locus_tag="ACIZE9_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HGC6093208.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(18514..19410)
                     /gene="murQ"
                     /locus_tag="ACIZE9_001339"
     CDS             complement(18514..19410)
                     /gene="murQ"
                     /locus_tag="ACIZE9_001339"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HGC6093209.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(19413..20474)
                     /locus_tag="ACIZE9_001340"
     CDS             complement(19413..20474)
                     /locus_tag="ACIZE9_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HGC6093210.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(20685..21212)
                     /locus_tag="ACIZE9_001341"
     CDS             complement(20685..21212)
                     /locus_tag="ACIZE9_001341"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGC6093211.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(21279..22781)
                     /gene="eat(A)"
                     /locus_tag="ACIZE9_001342"
     CDS             complement(21279..22781)
                     /gene="eat(A)"
                     /locus_tag="ACIZE9_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HGC6093212.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(23039..24160)
                     /locus_tag="ACIZE9_001343"
     CDS             complement(23039..24160)
                     /locus_tag="ACIZE9_001343"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGC6093213.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            24286..25227
                     /locus_tag="ACIZE9_001344"
     CDS             24286..25227
                     /locus_tag="ACIZE9_001344"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HGC6093214.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(25377..26273)
                     /locus_tag="ACIZE9_001345"
     CDS             complement(25377..26273)
                     /locus_tag="ACIZE9_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HGC6093215.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            26542..27882
                     /locus_tag="ACIZE9_001346"
     CDS             26542..27882
                     /locus_tag="ACIZE9_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6093216.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            28100..28543
                     /locus_tag="ACIZE9_001347"
     CDS             28100..28543
                     /locus_tag="ACIZE9_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HGC6093217.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(29047..30465)
                     /gene="nhaC"
                     /locus_tag="ACIZE9_001348"
     CDS             complement(29047..30465)
                     /gene="nhaC"
                     /locus_tag="ACIZE9_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HGC6093218.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(30868..32091)
                     /locus_tag="ACIZE9_001349"
     CDS             complement(30868..32091)
                     /locus_tag="ACIZE9_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGC6093219.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(32122..32961)
                     /locus_tag="ACIZE9_001350"
     CDS             complement(32122..32961)
                     /locus_tag="ACIZE9_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGC6093220.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(32978..33658)
                     /locus_tag="ACIZE9_001351"
     CDS             complement(32978..33658)
                     /locus_tag="ACIZE9_001351"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGC6093221.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(33660..34733)
                     /locus_tag="ACIZE9_001352"
     CDS             complement(33660..34733)
                     /locus_tag="ACIZE9_001352"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGC6093222.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(34789..35027)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(35070..35303)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(35380..36051)
                     /locus_tag="ACIZE9_001353"
     CDS             complement(35380..36051)
                     /locus_tag="ACIZE9_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6093223.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(36138..38786)
                     /gene="mgtA"
                     /locus_tag="ACIZE9_001354"
     CDS             complement(36138..38786)
                     /gene="mgtA"
                     /locus_tag="ACIZE9_001354"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HGC6093224.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(39128..39302)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            39475..39912
                     /gene="ndk"
                     /locus_tag="ACIZE9_001355"
     CDS             39475..39912
                     /gene="ndk"
                     /locus_tag="ACIZE9_001355"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGC6093225.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(39934..40800)
                     /locus_tag="ACIZE9_001356"
     CDS             complement(39934..40800)
                     /locus_tag="ACIZE9_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGC6093226.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(40960..43053)
                     /locus_tag="ACIZE9_001357"
     CDS             complement(40960..43053)
                     /locus_tag="ACIZE9_001357"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HGC6093227.1"
                     /translation="MTQLKKMCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT        12613 a         9151 c         7717 g        14199 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct attttttata
     7741 gtaattcctt cagatacttt cttgcctcat cattgaaacg cagtgattct tctaacttct
     7801 gataatattc caacgcttgt ttctgagctt cagtaaaacg ataatgtttt cctttccatt
     7861 tgtcgattgt ctcttgcaca tttccagatt ggatatcttt cactactagt tgccattttt
     7921 cttttgagac tgtacggtct ttcttatcag cagattgtat agcttctcgt tctttacgca
     7981 atacttttaa aaaaccattt ctgactatcc gaggaatgct gtcgaagaac ccttctgtaa
     8041 aaccatagcg acaatattgc ttccaaataa atagatagat ttttggttgg atgaatcgtt
     8101 ggtttttcgc aaaatattcc atctgagcag tgacttctgg tgttcgttga cgttttgtct
     8161 ttctcaacac ggaaataaat gtttcaaaat aagcattagg atgtactggc acttcttcat
     8221 atacgatgga ttgccaatct ttacgtaaaa atgcgcgata gttgatcaag aattcttcta
     8281 catcctttac taattcttct gcaaagtcgt caaatagttc tttttttatc tgtcgctttt
     8341 ttgactgccc attgatgtgt tcacttattt tcttgatttc attttccaat gcttgataat
     8401 ccgctatgta aatcggcatt tctacttggc gaaattctgc gagccgctga gctaatttta
     8461 tatccggtaa atatggctgt ttcatccgac gattttggta caagacaaaa cagtattttt
     8521 gccatagtcc ttcaggaaaa tcgatattct tctgcttaag ccataataat tcgtctaagg
     8581 ccagatcaac ttttgtcatt ccctgatgga tcgaagctgc cactgtcgga gagacatgca
     8641 ggtgatcggc aaagtggttg atgcctagtt ttaggatctt tccggttttt ggcgatttaa
     8701 cgatgtattg cacttttaat tctctaccac actcacaata caatttttgc tggcttcgtt
     8761 ttgttcgaaa aaacggattg atcttgaagt cagaaaacac ccaatctgtt gcagctaaat
     8821 aatgttcttc cataaaacga gagctgatta gatatcggcg gtgcttatcg actagttccc
     8881 gctgtttttt cgttaatttt gcatagatct cccaacgttg actgcttgtg tattgtttag
     8941 aaattttgat gggatagctt ttgctgattt cttttggaaa ccattcttca aagacggatt
     9001 gccattcttc cacggctgtt tctttccttt ctaattacaa aaagctggct actaacataa
     9061 cgttagcaac cagccagtgt ttcttgctaa attagtgagt tgttccggca tttccggaaa
     9121 tatcttcttt attttctact gctgcttcaa ctgcataagt caaagaagaa gcaatgtctt
     9181 ctaaagacat agaaggcgta cccactggac gatcgatcac ttgatcgggt gagaatggca
     9241 cgtggatgaa cccacctcga attgccggga attgtgtttc gatcaaatga agcaaacgat
     9301 acatgatatc attgcagaca aatgttcctg ctgtataaga gatgtacgct ggtagaccat
     9361 gatcttgtac attttttgtc attgctttga ttggcaatga ggtaaagtaa gcggctggac
     9421 cgttttcttc taaagccgta tcgaatggct gatttccttc attatcaggg attcttgctt
     9481 ctgctagatt gattgcgaca cgttcgaacg agactgctga ccgcccacct gcttgtccga
     9541 cacagatcac gacatctggt tggtgctgtt ggatggcttc tttgactact tgactgcttt
     9601 tttcgaatac ggtcggtact tccactttga tgatttcagc accgctgatt tcatctggca
     9661 ttttttttac tgcttcatag gctggattca ctttgtcccc accaaatgga tcaaaacctg
     9721 ttactagtac tttcatctgt tgttcctccg tccgattgat ttaacatatg gttatctttt
     9781 atcataccat tttccttgaa cagcgtaaat aaaggaaaca atagtttaaa taacataaca
     9841 gatcaaactt aatatattct tataaaaaaa atagtgttcc actacaatgt tagaagaggt
     9901 tgcgacaatt attctgtcac aacccctctc ttctattatt taaatagaat catataagca
     9961 atttggaaaa ctagcataaa taacgcaata aacaactggt ttttgatcac tccgtatttg
    10021 tctttcatct ccagcatcgc tacaggcacg atattgaagt tagcagccat cggtgtcagc
    10081 agggtcccac aaaaaccgca agtcaatgca accattccta ttaacgctgg attcgctcca
    10141 tgactaaata cgaatggtgc accgatccca accgtcatca cggtgatggc cgcaaatgca
    10201 ttccccatga ttaccgtaaa tatcaccatg ccaagagcgt aaatgatgat gccgatgttc
    10261 acatttcctt ctggaacgat cgtacctact gcattggaaa tcactgtccc aactccagcg
    10321 cttgtaaata ccgcacctag agaagctaaa agcattggca acatgcttaa cggccctact
    10381 gtgcccagca tatctgctgc atcatctaaa aatgtacttg gtcgattatc tcgagaaaag
    10441 aacatcaaga ttagcatggc tgcaaaaaca ccgacgccca cgccgactaa agcacctaaa
    10501 ttggtaaata gagcaaacaa gatcgcaaag acaccgatac tcaaagctgg aataaaaatt
    10561 ttcattccta gtttgtctga cattttttcc atatattctt ttgatggaag ccggctttct
    10621 cctttgctga ctttcttagc aattgctggt atggtcatcg caaagatcaa gccaccgttc
    10681 acgattgccg gaagccatct tcctcctgca ataactaccc ctaagaccgt ccagaaaaag
    10741 gctgacccat aacgatgagg attggtttta tctgttaaat ttcttactcc agtgtaaatc
    10801 aatacgagtc ccatcacgat ataaaggatc tccagtaatt tatcgcctaa taaaatatca
    10861 ggatttgtaa aaaagtccat cttattgccc ctttcctgga taatatttct tcgctaattt
    10921 cttttcttta agatagaagt agacacttgc cacaactaaa gccgtgatag ccactggaac
    10981 ttccactaaa gcaagctgtc ccaatgttac gtcatatcct agatctttca gtgttgattg
    11041 gactagcaac gcccctgctc ctccgatgaa tagtacttgg ccaaagaacc agcagacatt
    11101 ttccatagct gaagccatac cttttagttc ttcttcatgc ttaggatgga cttctaaccc
    11161 ttttgattcg atggtcccca atgccatcgg taaaatgatt ggacgaacaa atccagcaac
    11221 tccaccaaaa ctcacgttaa aagccgcaaa gatcattcga aagatcccat aaatatctac
    11281 aatcatacca gcagatactt tcttgaatcg cttgatcaag gaagccgctg attctttcag
    11341 accatttctt tcaagcgttc ctgttgccaa cataatgatg ataaaaatcg ccatcccgcg
    11401 attgtttaca aaacttgtac ctaaaagttc taacattcct tgaatgccaa gaccgccagt
    11461 caaagctgta acaactaaag caaccattac gatcaatatc gagtctaatt taaatgcaaa
    11521 cccgagaata acaatcaaga cgcctaaaag gctaagataa ttttccatat attttcctcc
    11581 ataaaatgac aatatttttt taattataaa gcaaaacaca taaaaaatat agttgttttc
    11641 tcacgaaata gacactattt ttaaatattt ttcgttattt ttttatcaca aaaattatct
    11701 tacttattgt aaggtaaagc tttttttaat ttattgcccg ataatatata gaaataaggt
    11761 ctagttactg ttttttttaa atgattaata aataacaact tctttctatg aaattgcaaa
    11821 gcattcatct tcttttccgc taacgatata tccgtcagtg cttggtacac tttactaaaa
    11881 agtatgagat tgccgatatc tggataggtg tgctatacta cagaaaaaga tatacaatct
    11941 gccaccgggt aggataaaga ggatgatcat tccattaggt ctttgaaggg atgattttcc
    12001 tctttttgtg tattttttta tagttaagga ggaatgtaag tatggcatgg atggaattaa
    12061 tcatagcagg aattttggaa gtattctggt caacgatgat gaaatggagt gatggttttt
    12121 ctaaaatcaa ttattctttt tacacagtga ttggcatgat tgctagtttt tactttttgt
    12181 caaaggcaat caaaagtttg ccgatgagtc tctcttatcc tatctggaca gggattggcg
    12241 cagttggttc ggtcataatt ggtgtggtct tgtttcatga taagctgaat ctttccactt
    12301 ggttctttgt ggggatgcta ctcatcagta tcattggcat caagattact agcggccact
    12361 agacacttgg aataagtact gatcagaaaa aataagcctt tttatttaat attcaatttt
    12421 tttatgaaaa aataagaaat aagtccaatg acctagcgac ttctccactc atcaggtgta
    12481 tgcttgtact atctatagaa aaggagtgaa tatttttgaa aagtctttcg gtccaagaat
    12541 tatccaagaa ctttggtcac aaacaagccc tcagcgatgt cagttttagc ttatcccctg
    12601 gcaaaatcgt tggattagta ggtcctaatg gcgctggaaa aacaacgatc atgaaagcta
    12661 ttttaggact gatccattac tcagatggaa caatctgtat tggtgaaaat gagatttctc
    12721 cctctagtca taaagggttg gaacaagtag gagcattgat cgaatacccg ggtatctatc
    12781 cattcttaac aggctatgat catctgaagt tattctctga aaccaacgat gtatctgcta
    12841 tcgacactat cgtgaatcag ctcaagatgg aaaagtacat tcacaaaaaa gcgaaatcct
    12901 actcgttggg aatgaaacaa aaattgggaa ttgctcttgc cttactgaac catccgtcta
    12961 tcgttatttt agatgagccg atgaacggtt tggatccaca agcaacaaga gatgtgcgaa
    13021 aaatcattac cgacttggct actcagggca cctctttctt gatctccagt cacttactca
    13081 gcgagcttga aaaaatggtc gatgagctga tcctgatcaa tcaaggaaag atcatcaaac
    13141 aatgtacaat ggctgaattg aaccaaacag cgcaagattt catcgttatc tctacaacaa
    13201 atgatctagc tgctcgaacg atcttgacag aagctggata tactttggaa gatcctgata
    13261 aaatcaagct tttaaaagaa aacgaagaat tattaggaac cgtgatccag ctattgtctg
    13321 cacaaaatat ccatgtgaca gacgtccagc atctgacgaa tgatttggaa tcttctctat
    13381 tggaaattct ggattcagta aagggggaag aagaaaaatg acattgcttg taaaacaaga
    13441 attatttaaa ttgatcaaga aaaagtcaac tgctgtttta tctgttctat tagttgtttt
    13501 gctcatagga acagcacttc tagccaaaaa atacacgacg atcattgatc cagttgaaat
    13561 gactgctcag ctttttagtg ccacatcttg gattgtcttt atcatgattg cagctgcaag
    13621 cacgatcatt tcgatggaag cacaatatgg tacattgaaa aatctccttt atcgaaagta
    13681 ttctcgagga gaaatattag taagcaaatg gatcacatta gttatttatt ctgtttattt
    13741 atacctttta gctattattg tcactgtgtt gatgaaactg attcttttcc cttcgatttc
    13801 cttcacggag aaggtttcta ctggtcaaac actgatccaa agcttgttca cttatacttt
    13861 gggtagttat atcggtttat ggctgatttt aagtttagtg ttgatgattg cttgctttat
    13921 caatagttcc ggcgcatcca tctcagcagg aatcgtcttt tattttgctt cgtcaatcat
    13981 atctggtatc cttattgcac tcatccaaaa atgggagtgg atcaaatgga atccgatcag
    14041 tatgttgaat ctgcaaaacc aaattggaaa cgaagagatc atgaagcaat tgactcatct
    14101 ttctactaat caaatgctat tcggtaattt agcttacatc gttttgttct tagcattagg
    14161 atatctcgta tttaagcgaa aaaatgtatg atgactcatc aaaaaagagg ctgtgaaaga
    14221 gacgttcagc cttattgccg attggctgtc tcttaaacac cgtttattct gaaaaaggag
    14281 ctgtgacaac atttgtgtca cagctccttt cctagtatgt ttttgaataa acgacaggct
    14341 cacaacctct ctttatactt cttttatact tctatacgtg aagcatccca gtggcaaata
    14401 aaaccattgc aatcactccg accatcgtca cacctataag taaaatctta tctaagtgga
    14461 tatgttgtac aggctcgttt tgctccttac gtgctttgag gtaaaaataa atgcctggca
    14521 agaaaagaac aagaacaagc attacttcat taaaggctac gactagcata gcccatactt
    14581 gaaaggcact tgctaaaagc cctactaaaa attggaccca ttctttccgc tgataagaaa
    14641 gtttcatttg gtacaatcct aagaaaagcc acgtgaagaa aatagctgct gtaccaagtg
    14701 tgtaagcaaa gttataagca ctgtcagtga ataataatga aagtaaaaag acattcgtac
    14761 ataacgtcgt caatacgata gcataagttg gtgccccatt tttgttgagt tttccccatg
    14821 ctttaggcaa aagtccgtct tcagccatgt ttcccattgt ttcaatcggt aagatcgtcc
    14881 atgagagcca aacaccaact aaagaaatga tcaaaccgcc gttgatcacg actgctcccc
    14941 atttaccaac catcatttca aacacatagc ccatagcagg ctgcgccttg atcgtttgca
    15001 gctgattcat cgtcattgtc ccatatggaa gcatggaaac caagacgtaa ataataatca
    15061 agccgaatat ccctagaatc gttgctttcc caacatctga ttgttttttt gctcgtgaac
    15121 ctacgacaga ggctccttca ataccaacaa atacccaaag catcaccatg atgcaactca
    15181 atacttgact ggaaaacggg atcggctgtc cattcgcatt caatataatg tcgctagaaa
    15241 agttatcaat gaattgttgg atcgaaaacg tgctgatagc tactacaata aataaaaata
    15301 atggcactaa tttacagaat gtgacgatag cattgacgaa actagcattt tcgactcccc
    15361 gattcactag ccatgcatat ccccataaaa agactgtact catcacgatc gatgccagat
    15421 tttgcccacc ttcaaatact gggaagaaat atcctaatgc gctcatcaac aatgttgcaa
    15481 aagctacgtt gcctaaccag catgtgagcc agtaacccca accgctgata aaaccagcga
    15541 aacggccaaa accttcttct gcgtaactaa agatcccgcc ttttaaatct ggacgttttt
    15601 tattgatatt attgatcgac aaggagagca tcaacattgc tgttcctacg agtacccaac
    15661 tgaaaatagc tgggccgcca gccgatccgg agatgtccgt cataatacca aatacgccac
    15721 ctccaatcgc tgaaccaatt actaaggcag caagtggaat taaaccaatt ccttttttct
    15781 gttgctctgt atccatgtaa gcatcctcca aaataaaacc gcttttatca aaaagtataa
    15841 caaacctttt ttatttttac ttaattaata aaaactttaa tagaaatata attctaccgg
    15901 cttttttctc attatacaag caaagcgcct agtccctttc caaattacac caccaaaaaa
    15961 cttaaaaaag atgctatact aaaaggaaag aattggagga tgatccatga acattttata
    16021 tatatcgatt tcaggaaata cgcgtgcctt tgccaaacat ctagcagaat atgctgaaaa
    16081 aatgcatgca gaagatcctg tcaatcctga agttacttta aaagaaatcc atgaaaatag
    16141 tgattttacg aaagaaacag aaccattttt tactttcgtt cctacttatt tagacggcgg
    16201 aaatggttta gataacggtg atacagaaat cttgaccgaa acgatgcgtg aatatctgga
    16261 acatgaagac aatcataaac tttgtcttgg tgtagtcggt agcggaaata aaaacttcaa
    16321 taatcagtat tgtctaacag ccaaacaata tgcacaaaca tttggctttc ctttcttggc
    16381 agattatgaa ttacggggaa caccatctga tgtgacacga atttatcaga ttttagcaga
    16441 aaacaataaa taataaaaaa gaagaagctg aaaaatagat ttcagtttct tctttcgttt
    16501 ctattgtttc tatcatatta agctttgaca tccatcacag gtgcttttgc ttttgcttta
    16561 cctgtttttt ccaagacaaa gttttttaca cgatccatat tggttaccaa gacgatcatg
    16621 gatgtttctt tgcctgctgc tttgatcgct tctaagtcag cttctgctac aagcgtatca
    16681 ggtgtcactt gctgcccttc tgttactttc acatcaaatg gcgtaccgcc taagtcaact
    16741 gtgttgattc ccatatgaag caagatttct aaaccatttg gcgttgtgat cccaatagcg
    16801 tgtttcgttg ggaagacaga gctgactacc ccagtaactg gagaatagat atgtccgttt
    16861 tctggttcta caaagtagcc ttcacccatc atcttttgtg caaaaactgg atcacttgct
    16921 ttatctaaag aaacaactgt tccgtcagca actgatgaga ggatagtcac actttcagct
    16981 gaagtttgag gtactacttt ttcaggcact tcatttactg tggctgtttc agtcgctaat
    17041 tcttcttttt ctaaacggtc tttaggaata ccgaagaaga atgtagcaac gaagccacca
    17101 gcataagctg ccaataatcc aaggatgtag cctaaccatt taccgtcaga gatcaatggg
    17161 atcaaagcgg ctcctgaagg tccaatagcg atagccccga catttccgat cattccgatc
    17221 actgccccgc cgatacctcc accgatacaa gcagtaataa atgggcgtcc tagaggtaat
    17281 gttactccgt aaatcaatgg ttcgccgatt cctaggatcc cgactggtaa agctcctttg
    17341 atcatttctg ttaattcttt atcttttttg cagcgaatcc ataatgccaa tgctgcaccc
    17401 acttgtcctg caccagccat cgcaagaatt ggaagcaata gcgtacgacc agtttcatca
    17461 atcatttgca catggattgg agtcaaaatt tgatgcagtc cgaacataac catcggcaag
    17521 aataatgtgc ctagaacgaa gccggcaaat gctccaccaa cgccaagtac ccagttgatc
    17581 ccaccgacca tgccatcaga aatgaaacct gctaaaggca tgatgaagaa aatttcaatc
    17641 agaccgatgg caatcaatga aagagttggt gtaacgatga tatctaccgc atcaggtact
    17701 actttatgca gttttttctc aacgattgac aatagccaaa cagcgaagat gacacctagg
    17761 atcccacctt gtccagctgc aagagcttca ccagtaaata agtttttcag tggtgcttcc
    17821 ggattcatcc ctgtcagcat cacaacggcc ccgataactc caccaagagt tggtgttgca
    17881 ccaaaaactt gtgcagcatt gatacctgta tagataacta ggtagctaaa catcccgttt
    17941 ttcaagatgt tcatcacatc gatatattgt tgccatgttg ctgcatcaag tgttccggct
    18001 gtgactaagt ttgctaaaac tgcggcaatc cctgccacga tcccagtacc gacaaatgca
    18061 ggaatcattg gcacaaagat attagaaatg tcttttaata ccgatttgat tttagatggt
    18121 ttttgtttcg atttttgtgc cgctttcatt tcttgtgccc gttcgtttac acggtctttt
    18181 ccagatgctg atgaatttgc tgtagctgta cttacagaag aaagtttttc tcctaatttc
    18241 acgcctgcca aatcaaccat ttgctgtgct actttgttca ctttcccagg tccgatgatg
    18301 acttgaagct gttcatcttc tactacacca agcactcctg gaatcgcttt taattcagag
    18361 acatttacaa gatcatcatt gatgatcttc atacgcacac gagtcatgca gtggacaatg
    18421 ctttctacat tgcccatgcc gcctgcccct ttataaattt gttttgccag ttcttccaaa
    18481 gtcagttcgt tttttgccat ggtcttttcc ccctcataag gtccctttta caaatccgtt
    18541 tgcttcagct aattttgctt gagcttcctc tttatcacta tttgtcaaaa tcatgacgat
    18601 agccagctta acattttgat ctgcttcttc aaagtacttt tcagctgttt cgtaatcagc
    18661 ttctgtcgct tgcatgatga ttcgttttga gcgttcgatt agtttttcat ttgttggttt
    18721 gacatcgacc atcaagttat tgaatacttt acctatacca atcatactga tagtagaaat
    18781 catattcaag ataagttttt gtgctgttcc tgacttcaat cgagtagagc ctgtcaaaaa
    18841 ttctggacct gcatcgactt cgattgggaa atccgcgtgt ttactgattt cggcttgttt
    18901 attgcaagaa atcgttcctg tgacagcacc gatcgatttt gcgtaatcta atccaccgat
    18961 cacatatggt gtacgaccgc tagctgcgat accaataact atatcatttt ttgtcaaatt
    19021 cagcttgatt agatcttctt gccctagctc ataagaatct tcggcccctt cgacagctac
    19081 agtcattgct tcttctccac cagcaattag acctatgacc atttccggtt ctacaccgaa
    19141 tgtcggtacg cattcagcag catctaacac acctagtctt ccacttgttc cggctcccat
    19201 ataaatcaga cgtccacctt ttttaaagga ctcaatcgtg ttagcaatca ctggttcgat
    19261 acttgtcagt tctttttcaa ccgcagcggc cactttctga tcttctttgt tcattagttg
    19321 aacggcttga gaaatactca tctcatctaa tccaaaagtt tcttggtttc tgcgttccgt
    19381 tgttaggttc tctaaattga ttttgctcat ttttatcttc cttcttttct tataaattga
    19441 tagttcatac cagctttgat ttggttgatc aatggtagct cttctttgat aactttagct
    19501 actacattca ctttttcatc cgctggcaaa tcatatttgg ttaattggat ctcacccata
    19561 tagcgcaaat acttttcgtt atctaaagta atagaccctt tcatacgcgt agctgtattt
    19621 cttgctggga taggcggaat ctctcgaaaa cgtgcatcta cgcttcgtat gacatctctt
    19681 gcatcgtctt gccgattcgt atgcttccct aatatatatt cgtaaaattc ttcatctaca
    19741 ggttccgtat ggagcaagac tgtctgttct ttttggaaag aagcaaattg ctcctgaacg
    19801 ttttctgaca gacctgcatc tccgatgtaa acaatatccg tgttacttgc taatagatct
    19861 agagcgcctg caagaggatg gatccctcga tgttcttcca aagttggcaa tccttgatat
    19921 agtgggcctc tcaactctgt atctcctggt acaaaacctt ggacaaggag accttgaatt
    19981 ttgagccatt gatttttttt ctgataccat tctttgtcca gccctgtttc gggacgtgga
    20041 taataattat gccaagcttc aatctgtgag aaatcagctt ctgcttcttt caattcatcg
    20101 atatctttag gcgtgatcgt gctagcattc aaactgattt tcaattgatg tgaccagtcg
    20161 gcaatctgct gattggaaat atgataatcc attcttaaac ctgttacacc aattgctttc
    20221 aaaggcgtta gatcttctaa tgaaaaaccc gctcgttcca atgcctctcc tgaaatatcg
    20281 accatcaatt ctagtttatt ctttttcgct tcgcttccta gttcgatcaa tcgcttttga
    20341 tatgccgaaa catcatcttc tggtatatgc atggaagtga aaataccgac aaagccattg
    20401 gatgccattt ggcggatata ctgtttcttc tcttctgaca aagaatcgtt cataaatatt
    20461 gaaaagccaa acatattatc cctctttttc tgtatccgtc ttcatttcta tgactagagt
    20521 atatatctaa agaaacaaaa tttcaatact tttattaaaa taattaaatt tcatttctaa
    20581 aggttgagtt tatattatca aaagaattgt cataacctaa aaaaggcact gctaagcaaa
    20641 agcagtgcct tgaaatattt tatttaaata acacaaaaac ataattactc ataagaaacc
    20701 aattctgtat tatctaccat gaatgtaaag aacccctcat taggcatcgg atgaaaataa
    20761 gcattgatca ctcttatcaa ggcattatgg caaactaaca gatagacatt ttcttcgtct
    20821 tcgatgcatt ctttcaataa aggaacgatc cgtgcataca catctaagac tgactcccca
    20881 tttgggaatc gtacagcgaa cgctaaacgt gctttttgaa agttctcatc tttgcttggc
    20941 agtccatcat aatccccaaa atccatttct accaatcgtt catcaacggt cagcggcaag
    21001 ctgagacgat cagcaactgc ttgtgctgta tctcttgctc gttgaagagg ggaatggatg
    21061 attttcgtga ttggaacagg caaatctact accttttctg ctagtttctg tgcctgcatc
    21121 tgtccttttt cagtcagcgg cacatctgcc cgtccgcaaa ctaatccttg tgcgttccaa
    21181 gttgtttctc cgtgtctcgt tacataaagc atgtgattct ctccttcgtt ggcaaagttc
    21241 cccttaacca taccttgttg ttcttgagat tacaagggtt agattctctc aagagaaata
    21301 atctcagtag atactttatc caggaaggtt tgatcatgtt ccactagtaa catggcaggt
    21361 ttcacgttca agatcagttg ttctaattgt tcttgattga agacatccaa ataattcaat
    21421 ggttcatccc atgtatatag ttcagctggc tgtgataaag atttagccaa ttccactttt
    21481 ttccgttggc ccatactcat ctgctcgatc ttgttatgaa aaacatctct ttccatccca
    21541 agctttcgga ggttgttcaa aaatgcttgg tagtctactt ggtttttctc tgcaaattcc
    21601 gccaacgttc ctcgattgtc ttcataattt tggcttgcat aactaatgct cagatgtttt
    21661 ggctggtatt tttctcctat aaccttgccg ttgaatgccc ccagaagata atggataatg
    21721 gatgactttc ctgcaccgtt aggacctgaa atcgccaccc gctgatgagg ctcgattgta
    21781 aaatgaattg gctcgaataa cagattttca taccctaatt gaagatcttc tacgcttaaa
    21841 agtcgcttat ggtgagacgc ttggctattc atcgtcaaag aatcgatata ttcgatatct
    21901 tttaatagtt tttctttctc gctgatctgg gtctccatcc gattcacgat tgctttggat
    21961 cgtttcatcg tccgtgcagc atcagcaccc actgctcctt tattcactcg tctagattca
    22021 gtatcgatga atccgacttg tttctttgtt ttatctcctt ctcgggaacg agaccattcg
    22081 gctttttcag ctgctgtttt ctttagccta ctgacttctt ttttcaattt ttcattttga
    22141 gccatttcaa attcatcacg aagttttttc tgttcttcat agatagagaa attcccttga
    22201 taaagttcca gttgactttt ttcgattgct aaaacatggt ccactacttc atcgataaat
    22261 ccccggtcat ggctgaccac gatgaagcct tgttttttct ttttcaaata agccgctact
    22321 tgttttctac cagagatatc caaatgattc gttggttcat cgattaacgg gaaatgagtg
    22381 tcatccacaa ataaaagtgc cagtaggact tttgtcttct ctccccccga tagtgtgctg
    22441 aattctctcc ataagatttc aggatctgtt tgcatcaatt ggagctctct ttcgatttcc
    22501 catatctcaa aatccgtaat atcatttaac acgtaatagg ttaaacgttc tttatctttt
    22561 gtctgttgcg ggaaataggc aaattcttgc tgatggatta cttgcccttg ataaggtagt
    22621 ttgttttgta gaatattcag taaagttgtc tttcctcgac cgtttcgtcc gataagtcct
    22681 agtttccatt gtgtgtcaaa atttagattt gcttgttcaa ataataatgt gccttggctg
    22741 tcgtagccga atgtcagatt ttttatttcg attttagaca ttttccatca cctcgtaaaa
    22801 aaagaccagt cctattttca gaactggcta aagaggatgc aagggttgga tacacacaaa
    22861 aagacccata catcgaaaaa accaagccaa tcccgaaaat ctgcacactg cttccttgtc
    22921 tccacaaggt acagtctgaa tgcagctttc atcaatcgac ttaatttttc aatgcacgga
    22981 tccctcactt tgtcctatat ttgaaattac gatagcataa agaaaatgat tttgtcaact
    23041 acttcgggag gatggtgaaa aatctgctaa gtgtctgtcc taagattttt gttttttcta
    23101 atgtttgcct gtgttccatt gcttcttcta aacctattgg acccaaatga atacttaaga
    23161 caattgggag aaaatcagaa agtccttcta gctcttggtc tctacttccg caaatagcga
    23221 ttattggttt tcgatatttt tttgcaagca ctgctacacc gtatggaact tttccgtgga
    23281 tcgtttgctg atcgatccgc ccttctcctg taatgatgac atctgcttgt tcgatctttt
    23341 tttccaatcc agtgatttgg ctgactaaat cgaaaccaga aaccatcttc gctcccaaca
    23401 aaaaaagggc tccaccaata ccgcctgctg ctccacttcc tggaatatca tctaaatcca
    23461 cctcccagaa atcttttatt tgctgagcaa tctttcctgc ttgtttatct aagaaagcta
    23521 gcgtcgtatc tattcctcct ttttgtcttc caaattgcca agcagctcct tgttgacctg
    23581 tatatggatt ggtaacatct gcagcgataa tcaattttac tttagaaaca agaacgtttc
    23641 ttcgatcaaa atgaagtttt ttagtagata ataaaggatt tccttctgtg tacccttcta
    23701 aagaagcacc caaggattgg agtaatccta gaccaccatc gctacacccg cttcctccta
    23761 aagtgacaat aatttgttct acttcttgaa gcagtgcatc tttaataagt tctcctaagg
    23821 cataactgga agcaagtcgg atagtttgat ccgttggttt atcaagtaga tctaacccca
    23881 atgcttgtgc agattcgatg actgcggtgt tttttccttg ccaagttgtc aataaatagc
    23941 tgatttttcg ctgacggaat aagagatcca tcccatcaat ggtacgccat gttcccctga
    24001 gcgcgtaata gattgcttct gcagtatttt ctccgccatc tgcaatcggc acattgattt
    24061 ttcttccttt acgatcttcc cagccattta gaactgcctg atttagttca aatgaagaag
    24121 cacttccttt aaatgaatca attgccgcca aaatatccat ctgtatccct cactttcttc
    24181 ttaagtaaga cacttttttt catttttttc aaacaaaaca atgctatttt cttccatttt
    24241 tctatatact aaaagggaac tcattgaata aaggagagaa aaaacatgaa aatcgcaata
    24301 gctggggccg gagcaatggg cagccgaatc ggattgatgc tacatcaaag cggaaatgag
    24361 gtcctcttga tcgatcgttg gcctgctcac attgaagcca ttcgtacaaa tgggttgatt
    24421 gctgacttta acggtaaaga agtggtcgca aaactgccaa tctattcacc agaagaaatc
    24481 atcgaaagca acgaacacgt ggacttgatc gtagcattaa caaaagccaa tcaattagat
    24541 gatatgtttt gttcgatcca atccattatt actgacaata cttatgtttt gtgtttacta
    24601 aatggattag gtcatgaaga tgtactggaa aaatatgtgc caaagaaaaa tatcttattt
    24661 gggatcacga tgtggacagc tggtctagct ggtcccggaa aagtcacatt gttaggtgat
    24721 ggagaaatcg aactagagaa cttggaacca gaaggcgaag catttacaaa aaaagttgta
    24781 gaagtctttc aagaagcaaa tttaaatccg atctatagcc ataacgttcg ttattccatt
    24841 tggcgaaaag cttgtgtaaa tggaacattg aatggtttat gcacgatttt ggattgtaat
    24901 attgctgaac taggcgcgca aaaagcggca gagagcatgg ttcgaacaat cgtatctgaa
    24961 tttgcttcta tcgcagcaaa agaaggaatc atactagatc aagaagaagt gtaccaacat
    25021 attgcttcta cttatgatcc tgacaacatc gggttgcatt acccatctat gtaccaagac
    25081 ctgatcaaaa accatcgttt gactgaaatc gactacatca atggtgccat ttggcgaaaa
    25141 ggacaaaaat atgatattgc tacaccatat tgtgcctttt tgacccaatt agtccatgca
    25201 aaagaaggaa tccttggcgc agaataaaag gctctctgat gagaatcagc tgaatcagca
    25261 gctggttctc tttttttaag cccaataaaa gatcaaaaag aaaacacaac tctcatgatg
    25321 ccataagaat tgtgcttgtt tgtttcagta cataatctct tcaaaatgta ggttttttat
    25381 ttgttttcaa cagaggagag gtcatattcg tattgctcat aaatagtgga atcgttagtg
    25441 ataaatcgtt ttgcccaatt ttctgcatca taaaattcca atagctctga taggattggc
    25501 ttaaatggtg tatgcagaaa ttccggtaat tcatctaaat cacgttctcg aagcaaaaaa
    25561 atattttcag gacgataaaa atgataatga gcaatcgctt gattatccgt cactagtttc
    25621 ttttgaaaat acatggattc aaatgtccgc aaagtcactc cttgctgacc ctcccgcaac
    25681 agttccagaa tcccgcgcga ttcccctgtt tttttcaggt actcttcata agtaagatat
    25741 ccaggttgtt cattccctcg atgtggaaga atgaaatagt tggtcgtaac atctcttttt
    25801 ataaattcct gcttatagct ttctgctcgt tcttttctcc cattattcgt tgcaccaaaa
    25861 aatagatccg tctttggttc gctagaagaa aaattcatat gtttcgaata aaatgaacta
    25921 ttatgtttca gcccaagttc ttttgcttcc aaaaaatcaa aatgataaat ctcatcgatt
    25981 gccggttcat cttgtgcctg cttcagcatc gcctcgtgtt ctgctttgaa gtgattccaa
    26041 aaaaataaca caatttttgc attggtaaat gggcgcacgc gtcgagccat ctccatatca
    26101 aatccataat ctaaaaaaac gatcagctga taatttgcca actgttgtct agctgattta
    26161 atgaattccg actgtagtaa atcttttccg gaccaaacat ctaaagagcg gatggaaggc
    26221 aaaaaataaa gtgatttatt ttttgcaact agcagtacgt catttttgtt catcttttcc
    26281 gcctcacttt ctctgtcact ttttcctatg atagcctgtt taaatagtaa aaagccagta
    26341 aaacgtttcc tatatttgta tgaaaattta acatttgtat gaaaatatga tgaaataaat
    26401 cattcttcta ttaaaattcg cctaaaagtt ttctgaatag ttgtaattgt ctgaaaattt
    26461 gttatcatta gtcattgtta aatattgcta tttattctta atataaattt tgattgtgaa
    26521 tttaaaagaa agaggtcatt tatggaagat aaaaaattga aaaaacaact tagctccaga
    26581 catatcacca tgttagcttt aggtggagca atcggtgcag gtctatttaa aggaagtggc
    26641 gaagcgattg ggatcgccgg cccttctgta ttgattgctt ttttgattgg tgggctgatt
    26701 ttatatatcg tgatgaaagg tctgggaaaa atcgttttaa gcggtggcga cacgcatcac
    26761 ggattatctg gtttgatacg cccttatcta ggtgctcatt ctgctgattt tactgattgg
    26821 gtctactggt ctatgtggat tatcaatatc atcgctgaag ctgttgcagc tgcttccttt
    26881 ttgcagttgt ggttcccgca cattccagcc tgggtatttg tttttatgtt ggctgtttta
    26941 actacgatca tcaatcttta ttcggtacgg ttattcgcag aaacagaata ttggctggct
    27001 tttgctaaaa tcagtgtcat tatcttactg atcatttttg ctacttatct tgtcggtcag
    27061 caaatgttgg gcacaggcgt tttccctacc cttcagcaat tgactgacca tggtgggttt
    27121 actcctcatg gtatgaaggg aatcatcagt tctttgcttg tagttatcta ttcttacggc
    27181 ggttctgaac tgattgctat cacggtaagc gaagcagatg atcctaaacg tgcgattcct
    27241 aaagcaatca aaggtgtcat gggaagaatc atttcctttt acatcattcc tttgtttttg
    27301 cttttgattc tttttccttg gaatacttta gcaggcacga atgtcagtcc ttttgtgatg
    27361 gtatttgaaa aaatgaatat cccatttgca gcggatatcg tcaattttgt gattgtcctt
    27421 gctttgttct catctatcaa ttcgggtgtg tatgcatctt caagaatttt gttcttccgt
    27481 ttgaaggatc gaaaaggttc ctctagaaaa ctagctgttt taaacaagca tcaagtaccg
    27541 caacgtgctg ttttattttg taccagtgtt ctttatcttg gtgtagctct ttcttatttt
    27601 gtcggtgaca aattatttgg ctatctggca ggttcccttt cgtatacagt attattgatc
    27661 tggatcatta tcagtgcggc atcctttgta ctggcactaa gaaaaggaac attatgggat
    27721 aaaggaatca gcttttttgc attagctgtc ttaggattga ttttccttgg tatcctgttc
    27781 acgaactcca ttggggtaac tgtattgact ggcctgcttt acctgttcat ttatttcagt
    27841 tatcaaaaaa agaatgatgc gttcgtattg acgaatgaat gaaatcgata gaaaatttta
    27901 ttttatttat gtggaataga tggagctatt gaagaaagga gttgtgacaa aagtcttgtt
    27961 gcaactcctt tttccgaata aacagtctca tgacctcttg gtaaacggtg ttcaaaaacc
    28021 ctctgtgcaa aataattgat tgttctccat gctcatgaca tgatagaaga aaggaatgaa
    28081 aaaaaggagt ttgttttaaa tgaaaaagta ttggaagttt ttgttgatga tcggtgtttc
    28141 aacggtagtt atgtttggta tgatgtactt gaatgtctat gcgctcgatc atatcttctt
    28201 cagtcgtaca cgagtattca tggcgttgat gatgggtgca gtcatggcag tcatcatgct
    28261 gttgttcatg tggaaaatgt atgaaaacaa aaagataaat gttatgatct tagccgctag
    28321 tcttcttgtt tttgccggtt ccttgtttat ggtacgaagc caaactactg tcaacgacac
    28381 agcttggatg aaggccatga ttcctcatca ttctatcgct atcctggcaa gtaaacgagc
    28441 tgatttaaaa gatcctgaag taaaaaaatt agcggaagaa atcattcagg cacaagaaga
    28501 agagatcgac aaaatgaaaa aaatgatcaa agaaatggaa tgaccattat ccgtccaaat
    28561 aaaaaaagag gatgttccag aagttatcag cttcaagaaa taagaagaag ctacttctgg
    28621 aacgccgtga ataaggggtt gtgaaaaagc tgccctgcat caagtaataa gaacagccaa
    28681 acaaaaatag cttctcctat ttttcgtttg gttaggctta ttaccgcaga tgcaagcttt
    28741 tgaacaccgt ttattaagag gttgtaaaat cagcgttctg acctgagtat tagagagaca
    28801 aatggaaaaa tagttcctca tattttgcca ttttttgagc taataccgag ggtcagctga
    28861 ttgaacaccg tttatcgaga ggttgtgaaa aagtcgctta gtttcgcgta ttaagaaaaa
    28921 ttttgtgaaa tggctttcca catttttgta taaatttggc ttaataccga gaaactggct
    28981 tttgaatacc gtttattcgt aaaagggatt gtgacaaaag tcttgtcaca atcccttttt
    29041 atgtttttat tgttctaatt gcgctgtctt gcttactgct tcttgcggtt tcacaaattt
    29101 ttttgagatt ccccaacctg tgaaggcact gaccatcgaa aacacaggag aaagcaaact
    29161 gaaaaatacg aatggcaagt aagtgagtgt aggaatacca aatgtacttg ctacgaaact
    29221 tccggcaatt ccccaaggca ctaagtagtt gattactgtt ccaccatctt ctagcgttct
    29281 acctaataca gttggatcaa atcctgcttt ttcataagtt tctttaaatg cattaccagg
    29341 cagaataaca gataggaatt gttcaccaat aaaaatattt actccgatac ttgtcatcaa
    29401 tgttgtaaaa atcaaatttg gtgtgttcgt catctttctt gatactcgtt ccatcacggt
    29461 tgagatcaag ccaaattcga tcaacaatcc acctaatgac aaagttagaa taatcaatga
    29521 cacagtaggc atcatacttt cgattcctcc gcggctaagc agtgaatcga tttgttggtt
    29581 tccagtattt gaaacaaacc ctgattcgat gaccccagcc aacttcgtta aggaagtttg
    29641 tgggttttga ataaaaatca ttcctactgc tacagcgata ttcaacaaaa tcgttaaaat
    29701 tgccggcacc tttttccatg cacacagtaa cattaaaaat aaaggaatca gtgaccagat
    29761 tgaaatagta aagtttgctt ctagaacatc agtcacttca cgaatagatg aaagacttgc
    29821 ggctttactt gtgtgtccta aaatcatgaa taaaaagaaa gaaacaacaa atgccgggac
    29881 agttgaccac atcatatgct tgatgtgttt gaacaaatcg gcatcaacaa tagctgctgc
    29941 tagatttgtt gattcggata atggagacat cttatctcca aaaacggcac ctgaaacaat
    30001 agctccaaca accagcgctg gatttaagcc tagtgttgtc ccaataccga aaaatgcaat
    30061 cccaatcgtt gacataacag taaaggcact ccctacagcg ctacctacga ttgcacacac
    30121 aacaaataca gaagggacaa accactggac actgatcaat ttgaacccaa tgaccattag
    30181 agttggaatg atccctgctt gtatccatac agcaatcaat gaaccgacta aaataaaaat
    30241 aaagattggg atgattcctg gtttgatgcc attgatgatt ccttcgtgca gccaatctgt
    30301 cgggtatctt tttatcactg catacaacat gaccattccg atcgctgcta agatcgtgat
    30361 attaggtgag acctttaatc cgacaacgcc aatcgcaatg cctaaaacaa taaccattaa
    30421 tacaagtgtt gcttctaaaa aacttggtgt tccttttttt cccatgataa tctctccttt
    30481 tttagttgtt cttatgttct aaaaaagtta agatatcgga ttactccgcc gcaattcatc
    30541 cgcgattcct cctttataaa aataaaaaga cctgttttaa actaaggacg aatgactccg
    30601 cggtaccacc ttaattaaaa acagatctgt ttttcacttt caaactttta ttcaaatgta
    30661 tggactttcc atgtaattcg tcaattaggc ttgatcggtt cacagcgacc accgactttc
    30721 tgaacaaaac acctaaccgc tactgcgtga aaagttgact tgtacgaagt ttaccttcca
    30781 taagatcatt tgtcaatgaa aaagaaaata ttttttcatt tttctgaaaa ttatttttat
    30841 aactttcaca cacaagttta ttttttacta gaaagtagcg ccctcttgtt tttttcttgc
    30901 tactatttct tgatgttctt gcttgattct ttctaatagc tttggctctt tcaacagatc
    30961 aagagctgta ttggcgagta gttctgctgc aatcgcaata gaagcaaggc ctttgtcact
    31021 tttagcagca gctttgaatt cttctgtgtg tccggcaata tatgtctcag agattgctac
    31081 cgtaggctgg attgttggta tgacttggct gacatttcct acatcagaag aaccgagact
    31141 tgttctttgt tccgtttcta tttcttcatc tggaacacct gcttcttttg catgctggaa
    31201 gaataagtca tcaaaagaag gagtaacgat gacatcatca actgcatttt ggaacaatcc
    31261 aaactcaaaa gtcgtgcccg tacttatcgc agcacctcgt acgatatttt ccactttttc
    31321 atatacttta tctaatgttt gccgatttcc tgcacgtaaa tagaaacgtc cagcagcgta
    31381 atctggaatg acgttggcag ctactcctcc gtctgtaatg atcccatgga tattgacatc
    31441 ttttggcaat tgcaagcgta gagcgttgat tccattaaac acttggatca atgcttccaa
    31501 agcatttact cctttttcag gtgctgctgc tgcatgggaa gcgacaccgt aaaatttgat
    31561 gtcgactgga tcattcgcta aagattctgt cgttttccca taacgaaaag ctggatggac
    31621 gcataacgct acatcgacat cctcaaaaaa accttctcga acaaagctgc ctttagctga
    31681 tccgttctcg cccccttctt cccctggggt gccatataca cggatttctc caccagtttc
    31741 atcaatgaat tgcttcacta tgctggcggc taatacggag taagtaccaa acaaattatg
    31801 cccgcatgca tgaccaatac ctggtaaagc atcgaattct gccaaaaagg caattgtggg
    31861 accgggttta ttggaaatat aacgtgcatc aaaggctgtt cggtgtccag ctacttcttt
    31921 ttctacccaa aacctttctt tttctaattg tttaatcaac gctgctgagg aataaaactc
    31981 atagttactt acttcaggat gttcgtggat atctagagca agtgcttgat attctggtaa
    32041 acgatattgg attagatcct tcaattggtt tgttgagatt gttgttgtca taaaaaattc
    32101 ctcctatgct agtcattttt cttattttct cccgaatgtt tcccatgcag gcacgcttga
    32161 tccttttgat gttttctcga ttactttgac tgtgtcttct gtttgataag cgtctactat
    32221 tttttgatac gttttattgt tttcatcttc ttttcttgca acgatgatat tcacataagg
    32281 acgtgcatgg tcatccactg gttctaagaa gatggcatca gaagcaggat taaatccagc
    32341 atctacagct acaccgctat tgatcactga aatgtctaca tctgacaaag cacgtgctgt
    32401 ttgggaagca tctaattcag aaatgtctag attttttcta ttctcggtaa tatcagaaac
    32461 agtgggcgct tgtccttttg ccttatccac tttgatcaat ccagcagttt gcaataacag
    32521 aagagctctg ccgccatttg taacatcatt agggattgct acttttgctc cgtctttgat
    32581 atcagctaca tccttcaaag tgttagaata aattcccagc ggtgcattga cagtatttcc
    32641 gatcgatact aaatcagttc cgtgttcttt attgtaattg tctaaaaaga attgatgttg
    32701 gaaagaattc aaatcaatcg atccatctgc taaagccaca tttggttgat tgtaatctgt
    32761 aaatttcacg tattccaaat taatgttctc ctttttcaaa cggtctttca cgttgtccca
    32821 tacatctgta tcttctccaa taatccctag ttttacgata gtttcttttt tgtcagttgt
    32881 atctgctttt ccttggctac accctgccaa ccaaataatt gctacaaatg taatgactac
    32941 aaaacgaata atttttttca ttttttctcc tccactttca atgtgtaatt tttttaatca
    33001 gttgattact gataaattga cttaaaaaaa ctaagattag aatcaataat gtagccacaa
    33061 tcgttacatc tgtttggaat cgattatacc ctctcgatat agcaagattc cctaatccgc
    33121 ctgcacctac tgctccagcc atggtagtca gtccgatcac gttgatgata gtcaacgccg
    33181 agacccgaat gataccaggc aaaccttcta acaaatacac acgtaaaatg ataccgattg
    33241 gactggttcc catcgcttct gccgcttcga tcaccccagg atcaacttct agcagtgcgt
    33301 tctcgatttg acgagcaaaa aacggaacaa ctccaaaaat caatggcact aaagctgctt
    33361 tcgcaccaat cgtcgttcca actaagaaac gagtagtcaa tgctaaaaga gaaagcaaga
    33421 taatgaaagg gatggaacga atgatattga tcagcttatc aagtatttca aatagcagac
    33481 ggttagctag taatccatta gggcgtgtca ctactaacgt cacacctaag atgattccaa
    33541 tcatcccgcc aatgaatgct gtccaaaaag acatatatag tgtttgcttc gtcgcttcga
    33601 caaattcatc cggaatcaaa taaacattgg gcaaatatgt tttaaagaaa tcagtcattt
    33661 tatcttcctc cttcgatcac tttgatacga ctatctaaat cgtttttttg taaaatattt
    33721 atttttacac cagatttgat caaataatcc aatgcttttt tccgctgttt ggtttctcca
    33781 gctaaagtaa cgatcaaact ccctaacggc gtttcttgta ataactctac attgccatat
    33841 aaaatattcg ctgttacttg atatttgctg tacagatgag cgattagagg ttcgttcgtc
    33901 tgatttccaa tataacttaa ttccaccagc catttattgg cgatctgatc ggcaaaagca
    33961 gaatgggcaa tgatcgtttc taatgcttgg tcaagatgag tagctgttcg aataaaatct
    34021 ttggtcaatt cttcttcagg attgctgaag atctggatgc tgctaccttt ttcaacgatt
    34081 cttccatctt ccataaccgc taccttgttg cagatttctt tgacaacttg catctcatga
    34141 gtgatcagga cgattgttaa acctaactgg cgattcaatt tttttaacaa tgcaaggatc
    34201 tgaagggtcg ttttcggatc aagtgcactg gttgcttcat cacataataa taccttaggt
    34261 tcattcgcca aagctcgtgc gattgctact cgttgttttt gtccccccga cagttgttta
    34321 ggataagcag atgctttttc ttccaaaccg acaagttcca gtagttcatt cactttttga
    34381 cgacgttcct gtttcgattt tccagaatac tttaaagaaa aatcaacgtt gtcaaaaata
    34441 gttcggcttt ccattagatt gaaatgctga aagatcatac cgatggcctt tctttctttt
    34501 cgcaattctt tgggagagag ctgactcaga ttcgtctgat tgacaatgac ttctcctgct
    34561 gttggtttct gcagcaaatt catcacacga actaacgtac ttttccctgc acctgagtaa
    34621 ccgacgattc cataaacatc gcctttttca atcgttaaat ctacagaatc tactgcctgt
    34681 atctcttttt ctttttgttt gaaacataca gaaacatctc gcaattcaat cattaaaatt
    34741 cctccttatc taaaaaaagc gtcctcaaga aaatgaaaat gtcattttct tgaggacgct
    34801 tttttgcgtg ttaccacctc atgttcaagc tgtgttcaca cacaactcct cttcaagtac
    34861 gatcatactc tagcaagata tcggtcgcag ccgtcatcgc cttacatcta tgctcgggat
    34921 gaattgctcg atggccattt tccaatagtc gttccttgct tcttctcagc taccgaagct
    34981 ctctgtcaaa ggttcttcta tcgtacttac catttcaatg caaataatat tcaaaaaaaa
    35041 agtcctttta ctaacataaa ctatgtcagt aaaaggacga cgtatcgcgg taccaccttt
    35101 tttcggaagt ttccttccct caagcccaac atctcaaaaa gagagattgg cgttcgtttt
    35161 aacggtcgaa cagttccgaa tttgcctact tatcgacaaa ttattctcca aggccatttt
    35221 cagcttttct tacttgactc ttctcaccag ccagagcctc tctgcaaagt ttccaaactt
    35281 actttccttt tcaacgaaat cgatattttg ttgttgggat taatctacat gaggaaaact
    35341 gaaaagtcaa gtacgaaatt caaattattt tttctatatt tatttttctg tttttttatt
    35401 taacatttca ataacagttc gaagatcttt tccttccgca agaagtttca atttttcctt
    35461 ttcttcgacg gtataatttc ggacaaaact ggaatcaggt atcaaaacaa cgcctaatcc
    35521 tgctcgtgaa gcagctgttg ctcctactaa agaatcttcc actgcaaagg ctgaactagc
    35581 ttctaatcct gttcgttcca aagctgtcag ataaggaatc ggtgaaggct tgttctccga
    35641 cacttcgtct ccgaatgtaa acgtgtccaa gtaatcagct aatttaaagt gatccaagat
    35701 atctgttgct cttttcgtaa cagtggtcgt agcaatgcct agtttcatat gacgttcttt
    35761 taagtctgcc aatatttctt ttgcatatgg ttttaagtgg atggctccgc ttgtcagctg
    35821 ttgataaaaa tattcttcac gcttcgctcg gacttcctgt actttttcag ggctacctgc
    35881 tgctttcact aaaatatcaa aactttgttt ccagtttttt ccgccccaag cgtcaacgat
    35941 ttcttttggg atatggatat caaattgctg aaatccccaa agccagccat cacgatacgt
    36001 tttttctgtg tcaactaaca aaccatctaa atcaaatatt gcacctttca tctatacatt
    36061 aatcctttcc aaaacaatac acatagttta gcacgactgg tccaaaaaga acagaagcaa
    36121 agaaccagcc ttctcgttta taagagttct tggaatcgac ggatatagat tttcttcaca
    36181 gctgtcacaa gcgccagata agcgatgact gtagcaaata accataacca gtaattgcca
    36241 ggaagtggca tcaagcctaa ttcagcacca aaacttgtaa aaggaaggac agaaccgaca
    36301 ataattccta atgtagtgat aacaaacatg gcaaatgttg cgttgctttg gataaatggt
    36361 actttcggtg tacgcagtgc atggagcact aaggtttgtg tccatagtga ttcgacaaac
    36421 catcctgcat ggaataatgc gatgaaaatc actcgctgtg aactatccaa tgtatggaaa
    36481 cttccgccca ctacagcagg acaaataaca aaatacatca acaagtaagt agtaatatca
    36541 aatatcgaac ttgttggacc aaagtaaacc atgaattccc caatactaga tgcattccat
    36601 ttttttggct cgtccaaata ttctttatcc atccgatccc atggcaagga aatgcaggaa
    36661 acatcataga tcagattcaa aaacaaaagt tgtaaaggca gcattggtaa aaatggcagg
    36721 aacgtacttg caatcagcac ggaaaacata ttgccaaaat tagaacttgc tgtagccttg
    36781 atatatttca tgatattccc aaaagtttct cgtccagaaa gaaggcctct ttccaaaatc
    36841 gtcaaatctt tttctaaaag gatcacgtct gcagattctt tcgcaatatc cacagctgta
    36901 tctacagaaa taccgatatc agccactttc attgcaggag cgtcattgat accatctcct
    36961 aaaaatccga cagtatgacc atttttacgt aaagctgtcg tcaaacgtgc tttttgctga
    37021 ggattcaatt ttacgaatac ttcatggtct tcagctactt gtgctaattc atgatcactc
    37081 atttccgaga ttttctcacc ggtaaccaat tcattgatct ctagacctac ttgacggcac
    37141 actgaacgtg taactaattc gttgtcccca gtcagaactt ttacagctac accatgttct
    37201 ttcagagctt tcaacgcctg tttcgttgtt tcttttggtg gatcaaggaa agcaagataa
    37261 ccaatcaaaa ccatgtctga ctcatctttg actgaaaatt ctccaacgac gcttggattg
    37321 gtcttttgtg cgacaccaat cactcgtaag ccatcttcat taagtgactg tacttttgca
    37381 agtacggctt cttttcgttc ttttgttaat ggtgtaacag taccgccaag atcaataaat
    37441 ttagaaatgt tcagcatttc ttcaatcgcg ccttttgtga tcatttgtgt tttaccagct
    37501 ggatcagcaa ccacaacact catacgacga cgttcaaaat caaaaggaat ttcatccact
    37561 ttttgataat tgatcttatc tgtatctaaa gtttctgttg cttcatcaat gatagccaca
    37621 tctaacaaat ttttcagccc tgtttgatag tagctattta gatacgcatg gcgcaaaaca
    37681 cgatcatctt catttccttc acaatccata tgatattcaa gaatgatttt atcttgtgtc
    37741 aatgtccccg ttttatccgt acataacaca tcgattgcac caaagttctg gatggcattc
    37801 aaatttttga tcactgttcc ttttttggcc atcacacttg ctcctttgac caaattcgtc
    37861 gtaacgatca ttggaagcat ttcaggtgtt agaccaactg ctacagatag tccaaaaaga
    37921 aaagcttcta gccaatcccc ttttgtaagc ccattgatga cgataactgc tggagccatc
    37981 aatgacataa atttgatcag tagcatggat gttttatgga tgcctaattc aaagcttgat
    38041 tgaattggtt tttcagatag cgtttctgct acatgaccaa atagtgtttc atttccaaca
    38101 gaaacaatga ttccttccgc acttccactg atgacattac ttcccataaa gacaagattt
    38161 tcgtaacttg tttcgctttg ctgatcgtct tcacatactt tcgcatgctt ttctactgga
    38221 tagctttccc ctgtcaatgc tgcttgggaa atgaataaat cctttgcgga caataaacgc
    38281 atatccgctg gtatcatatc ccctgctgaa agccgaacaa gatctccaca gacgatttct
    38341 tccataggaa tctctgtgta ctttccatta cgttttacag ctgccgttac tttcacaagt
    38401 gatttcagtt tttcagccgc ttgattggaa cgtacggact gaatcaacgt cattgtcccg
    38461 ctgacgataa ccatagtgaa gataatggct acaccgaaaa gatctttatc tccaggagct
    38521 gctaatacat attccgtgat gaatgaaata attcctaatg cgatcaacac taatgtaaat
    38581 ggcgtgatgt atgctttcaa tatttctaca atgaatggtg tttttttgcc atatgaaatc
    38641 gcattttcac cgtaattttc tcttgaacgt tcgatttgtt cttctgtcaa tccatttgct
    38701 gatgcatgga atagttcaaa taattcttgt ttcgtttttc cagcaaaagc tgcatagatt
    38761 ttttgtgtat ctttcttttt ttccatctca atctctcctt tgtgtccaaa agacagctgt
    38821 tctcgctgct tttggtcttt agctattcat cggatcgata gagaaaaaac tgaaaggggc
    38881 tgagaacaga tagataatag ccctggcctt tcctctagat ccttgttttt cgaatgactg
    38941 tcatccattt gttctcatct cctttactaa gtaattttaa ttcatgactt ccaatcattt
    39001 ttcgaatagt tatttttcca attagaccac ctccttttta tttttcaccg atggggattt
    39061 gcggcaacaa aaaaacctct cgccaaatac tcagcgaaag gtttgaaaaa gcatattaaa
    39121 aaaagcttct cagatctcat cgttgagttt tgacactgta caacgtaaaa agcagatacc
    39181 tgcttttagc taccttatga aaagccttat ctcgacaatt cctgttctac ccattggcgt
    39241 ctctcgacgt ttttgggcag tagcctatgt ttgtatagga gcctcaccta acaaatctta
    39301 ttcggttttc cttcgttaat ataacaacta aaaaagagga tgtcaaatca attttccatg
    39361 tttttcatac tttttttaaa atacacacgt tatattcctg tctcacgcgg ttttatttgt
    39421 ctcattttcc acctcccgct ataatagaaa tatagtagga aacgaggtgc tgttatggaa
    39481 agaacacttg ttattatcaa gccagacggc gtgagacgcc atttagtcgg aagcatcatc
    39541 caacgttttg aagcaaaggg actggccatt gctgaaatga agtttgaaac tatgactcct
    39601 gaattagcaa aagaacatta tcagcacttg actgagcgca gtttttttga tgaactgatc
    39661 gattacatga cttccggtcc tgtcgtttat cttgtgctgg tcggcgagga agtgatcgat
    39721 atcgtccgta agatggttgg agcaacaaaa gctgccgatg ctgttccagg tacgatccga
    39781 ggagactacg cgctgccggg gactgaaaac atcattcacg cttctgattc ccgtgatgct
    39841 gcggtaaaag agatcgcccg ctttttcccg ccattcgata taaacaaacc gtctgaaaaa
    39901 gcggcgaagt gatacaaatt ctaaactgct ggtctagttg ctgggttcag caatggccag
    39961 cagttttttc tctaaggacc tccgttgatt ctttcctaac atatattcga gcactgtgaa
    40021 gaattcttgg tagtctttcg tcttttcttc ccctaaagca gcagaaatca atctttgata
    40081 ataatctgcc atcaatgttt catagatcac tgtacttctt tctttatgtg ataagctccg
    40141 tttcatatct tcattcacac tacgtgcctt tttcaaccga ccattttcta tataaaacga
    40201 agtcaggttc attaaaaaag taaagagata ctgctcatga ttgttcaact gtgctaatcg
    40261 tcgcattctt tttttgattt tcaaataatt gttctcaatg aaccgatcac tgaatatcca
    40321 aggaaaatca gctagaatag atagttcaaa ttgaccatag tctggtatct gcatcaagta
    40381 ttcttcaatg attcggcatt cataacgtaa aaattcaaat tctgtctcag atacttctgt
    40441 tttttcgacc atgtgaagat tcaaaaccaa ataatacaga tcttctgttt tcttaaaatg
    40501 cctacggtta ttgctgatct ctttataagg atcaaagctg tcttcttgta cccgatctag
    40561 cattcgtctt tttttcttta actttattgg ttcatccagc tggtttcgca tccattcata
    40621 ttctgcaagt gtcatgttca ttcgctctaa aaatgatctc aatgttacaa atgacatttt
    40681 tttcactgaa tttgtctcaa tcccgactag agaagtctta aaacagattc cttccgctaa
    40741 ttgggactgt gtcaacttct tgttgactcg aagtttcttg atcaattcac catcatacat
    40801 aatagttctc ctttttaatt taaatttttc cacattcaat aaatagatac gttaaaaagg
    40861 aaaaatacac gaaaaaaata aaaaaatgtt tttttcataa aaaataccaa ccttcaagca
    40921 ttagaatgtt gtctaactac tgaaggttgg tttgattgtt tattgattat ttttttgctg
    40981 ttcaacgtct gttcttgtta ctggatataa gttggttgtt gttttattac cattttttga
    41041 aaagacactt gtcgaatgtt cgcctttttg cttttcgatt gcttcattac gttccgcttc
    41101 atttttatag tcatattttt tcggatcaat cgtctcaaat ccgtttggca cataaaaccg
    41161 caagagattt tcctgattca gcttatctga aagacttaac gcagtcttga ctttttcctg
    41221 atctttggag atttcctcat cgattcctgc tgctttcgta tcgatgattt ctcctgtctg
    41281 attattgtaa gcttttcctc ctaggacggt gtatttgggt gtcacaaagt tcccatttcg
    41341 aaaagcaact acttgatcat gctgagaaga taataagtct gtaccaaaat gaagataatc
    41401 tttatcatcg attcccaata gatgtagtaa tgtcggcaaa acatcgattt ctccaccgta
    41461 ttcatgattg actgtccctt tagtataacc aggcatatgg atcatcaatg gcactcgttg
    41521 catctgtgcg ttgtcaaatt catcccatgt atctggatct ttaccaagag cgcttgctaa
    41581 atctttatta tctgtattcg agatcccaaa atgatccccg taaatcacaa agattgaatt
    41641 ttggtaaata ccagattttt tcaaatacgt aaaaaattgt tccaatgatt gatccagata
    41701 atgtgccgtt cgaacataat tatctactgt gctattgcca gtattcaaag atggaaagtc
    41761 gaaattcttg tcatccgtat aataaggcgt gtggttggtt acggaaagaa atttcgtgta
    41821 aaacggctgt tgtagatgct caagatattg ggcagattct ctgaataaat ctttatctaa
    41881 tatcccataa cctaacgttt cgtcggattc atcaaaataa gatcgatcaa agaaattgtc
    41941 ataacctaag tttttatata catgatctct attccaaaaa ctagctacat tcccatggaa
    42001 aacagcgctt gtatagcctt gcttttgtcc aaggatcgct ggtgcggctt gaaagacatt
    42061 gtctgaccca agttctgtga ataatgagcc ttgaggtaaa ccaaatgtgc cagtttccaa
    42121 catattttca gcatcacttg tctttccctg tcctacttca tgaaagaaat tgtcaaagct
    42181 gatcgttgct tgattctgga aaatactatt taaaaacggt gtgacttctt gtccgtctac
    42241 cttcatatta atcaaaaact gctggaaact ttctaaatgg agaacgatca catttttccc
    42301 tttagcgatc ccaaatgttt cgggatttgg ctctgcataa tgtttctttg tataatctaa
    42361 aacttcatca atcccattac tgcttgcatg cgcgcgaaca ctgctagtca ttcctgtttt
    42421 gattccgtca taaatagtat acgcatcgat tcctagatat ttgacaatat atgaacggtc
    42481 aaatgttcgc tgcagcaatt gtggacggtt ggcttcgctc agcgctagat ttcctgaaaa
    42541 aataagccct gaaagacagg taacagcgat agccatcggt ttgccgacag ggttgctttt
    42601 gataggtatt ttcttgacct tcaaccaaac cagtagccca atgaacacag cgatatccag
    42661 ccagtagatg acatcatggg gcttcatcaa agaaaaggag cttcctgaca atccttgcga
    42721 cactttcgaa aagcctaata cagatttgac tgtaatgaaa tctgtgaatt cccgataaaa
    42781 aataatattc aagtacaaca aaagcgtatt taaaatatca atgatcaaaa gaatagctaa
    42841 cgctggcttt ggctttttaa tatacaaaga aaggccaaaa aacaataagg tagtcgcaat
    42901 tgggttgatc cacaagataa agtactggat cgtaccttcc acacctaatg aaaaatctgc
    42961 atagtaggca atgatcgtct tcagccagaa aaagaaaaca gctgtcaaaa cgattgctaa
    43021 acgattttgg cacatttttt taagttgtgt cacgtatatc acttctctct attcacattt
    43081 tttcttattt tgctcctgaa aaatgaaaat ttcctaaaaa agttgttatc ttaagatttt
    43141 tttattcttt ctaaagatta ttccgtccac ttttcacagc ataaaaccgc tgcgatgtaa
    43201 gcgattaaac taatgaagag ataaaagtct tgtggtgacc gcttcactcc acggtattca
    43261 aaagccagtt tctcggtatt cgtacaaaaa aagaggctgt gacaaaattc ttgtcgcagc
    43321 tccttatttc ttgatgcagg acagcttttt cacaacttct tccttaaacg gtgttctcct
    43381 gccaactcct cggccacaag tcacaatatt tataaaacat gagaagctgt tttttgaaat
    43441 tgttccttgt ggctcagagt taaacggcag gctcaagacc tcttgataca cggtgttcaa
    43501 tcagctgacc ctcggtatta gattatgtca ggacgctaat tttacaacct cttggtaaac
    43561 ggtgttcaaa agcttgcatc tgcggtaata agcccaacca aacgaaaaat ataaggagct
    43621 attttttgaa attgctcctt gtggctcaga gttaaacggc aggctcaaga cctcttgata
//
LOCUS       DBBGSP010000022        41406 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000022 DBBGSP010000000
VERSION     DBBGSP010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 41406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.022"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            174..518
                     /locus_tag="ACIZE9_001358"
     CDS             174..518
                     /locus_tag="ACIZE9_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGC6093228.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            519..938
                     /locus_tag="ACIZE9_001359"
     CDS             519..938
                     /locus_tag="ACIZE9_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGC6093229.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1030..1380)
                     /locus_tag="ACIZE9_001360"
     CDS             complement(1030..1380)
                     /locus_tag="ACIZE9_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093230.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1346..2677)
                     /locus_tag="ACIZE9_001361"
     CDS             complement(1346..2677)
                     /locus_tag="ACIZE9_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HGC6093231.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2933..3499
                     /locus_tag="ACIZE9_001362"
     CDS             2933..3499
                     /locus_tag="ACIZE9_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6093232.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3644..3731
                     /locus_tag="ACIZE9_001363"
     tRNA            3644..3731
                     /locus_tag="ACIZE9_001363"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3676..3678,aa:Ser,seq:cga)
     gene            complement(3783..4988)
                     /locus_tag="ACIZE9_001364"
     CDS             complement(3783..4988)
                     /locus_tag="ACIZE9_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HGC6093233.1"
                     /translation="MAKKEIDKRIKKHLTKKGEEKYQFSLYLGVDPLTGKKRKTTRRG
                     FSTPLAAERALKRLEADIQEKGLQASTAQKSKKFEYVYGLWFENYKKTVKESTWSSTK
                     QIFDTHILKVFGDKFIDKIDVFFCQEAVNTWSDSHPKIFKKIKNYTSNVFDYAASLQI
                     ITSNPMKLVSIPRGEALDIEDKNIEFYTKEELIKFLEAIRNDDDERYLFFSLLAFTGI
                     RKGEAFALTWSDIDFKSKTLNINKTVTRGYQGRLIVNTPKSKSGKRKIYLDNDLISLL
                     RKYYTKNKTIVTIQRENLIFHHDGLLYNPTVSRSWLNVIYKHHPELTKRITTHGFRHT
                     HASLLFESGASLKDVQERLGHADIQTTSNIYTHVTETQNKKVINNFVAFMKNSTQGES
                     KGESKNILG"
     gene            complement(5126..5263)
                     /locus_tag="ACIZE9_001365"
     CDS             complement(5126..5263)
                     /locus_tag="ACIZE9_001365"
                     /inference="COORDINATES: protein motif:HMM:NF013630.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGC6093234.1"
                     /translation="MTLQPGEGTKQIAERAGITVDQLFALNGMDPNNYMLYPGQELRV
                     K"
     gene            complement(5565..6014)
                     /locus_tag="ACIZE9_001366"
     CDS             complement(5565..6014)
                     /locus_tag="ACIZE9_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein LysM"
                     /protein_id="HGC6093235.1"
                     /translation="MKKVITSLLVFASLLLFTACGKKVTTEDLKANDWLIEATKDDEP
                     NMIVSFSDHVVSFSVDTSSMKSTSSNDWEAMGEEFAKSLVDQMNYKFEYTLEGDVMTW
                     KDDKDKDNDAKYTVSKEDKNIILTPEKPNKSDDNEKLVLKPYKKEKN"
     gene            complement(6101..6301)
                     /locus_tag="ACIZE9_001367"
     CDS             complement(6101..6301)
                     /locus_tag="ACIZE9_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093236.1"
                     /translation="MKIGMRKPSIKKSISARTTGKAKRKVKKAVIPGYGKKGSGWIKD
                     PKKAAYNKVYKKTTFSFWDLFK"
     gene            complement(6330..6752)
                     /locus_tag="ACIZE9_001368"
     CDS             complement(6330..6752)
                     /locus_tag="ACIZE9_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGC6093237.1"
                     /translation="MYLPQIDNKINKLVKLYQTRNPFRIARELKILVLEEDLGEIYGY
                     YSKFKQIKMIHINSSLDEMGKWITCSHELGHCVLHPNENTPMLSKKTLVSELKIEKEA
                     NYFATHLTIDPTLDGFDHMTKYEKLVCFGLPDEFDRFL"
     gene            complement(6769..7191)
                     /locus_tag="ACIZE9_001369"
     CDS             complement(6769..7191)
                     /locus_tag="ACIZE9_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6093238.1"
                     /translation="MTTFERIKELAKNKNKNLQQVAKDLKYGENYFYSLNAGKQPTAE
                     KLQEIADYFDVSVDYLLGRTEKKRYYDLTEKDERDIQKELQSLIDDLSNADGMAFSKK
                     DNEMSEATREALIISLENALRIAKIEAKKKYTPKKYRD"
     gene            7482..7673
                     /locus_tag="ACIZE9_001370"
     CDS             7482..7673
                     /locus_tag="ACIZE9_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093239.1"
                     /translation="MSNLDNGRAAIKEFMKENGITMDDLATAYGHTRVRMQQILDGHW
                     SGPKANRTILEIIRDYRIR"
     gene            7684..7950
                     /locus_tag="ACIZE9_001371"
     CDS             7684..7950
                     /locus_tag="ACIZE9_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093240.1"
                     /translation="MNILSEEFLTRLRIAIVEVVKDALSQLSKKNLSETRYLKKIEAR
                     KYVGGVNDQGFEKLIAHGLKEIRIDGFLRYDKKDIDELMAKYKI"
     gene            7962..8132
                     /locus_tag="ACIZE9_001372"
     CDS             7962..8132
                     /locus_tag="ACIZE9_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093241.1"
                     /translation="MGKFNRTLVFSAPLIIYALGLWGSRQALIGTIVYMLWIFIGLDE
                     AEYRAKKPVGRD"
     gene            complement(8191..8670)
                     /locus_tag="ACIZE9_001373"
     CDS             complement(8191..8670)
                     /locus_tag="ACIZE9_001373"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093242.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
     gene            8715..9422
                     /locus_tag="ACIZE9_001374"
     CDS             8715..9422
                     /locus_tag="ACIZE9_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HGC6093243.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFDKKHRHVLTAIDELKEGVAEN
                     WADLFWEDTYVHPQNKQSYRIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKE
                     LKDQLPSIPATKREMALLALAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMV
                     RNKIRVICNQQHLNSKAKAELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMP
                     STATMTIIKQMELLEDE"
     gene            9415..9543
                     /locus_tag="ACIZE9_001375"
     CDS             9415..9543
                     /locus_tag="ACIZE9_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093244.1"
                     /translation="MNRAEALKIGVIIANRWWRHNKPNILSQQHIDKQKAWQQIKK"
     gene            9601..9942
                     /locus_tag="ACIZE9_001376"
     CDS             9601..9942
                     /locus_tag="ACIZE9_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093245.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            9935..10681
                     /locus_tag="ACIZE9_001377"
     CDS             9935..10681
                     /locus_tag="ACIZE9_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HGC6093246.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            10687..11373
                     /locus_tag="ACIZE9_001378"
     CDS             10687..11373
                     /locus_tag="ACIZE9_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HGC6093247.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            11380..12213
                     /locus_tag="ACIZE9_001379"
     CDS             11380..12213
                     /locus_tag="ACIZE9_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGC6093248.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEY
                     VINWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLP
                     I"
     gene            12230..13081
                     /locus_tag="ACIZE9_001380"
     CDS             12230..13081
                     /locus_tag="ACIZE9_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6093249.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            13078..13437
                     /locus_tag="ACIZE9_001381"
     CDS             13078..13437
                     /locus_tag="ACIZE9_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HGC6093250.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            13452..13613
                     /locus_tag="ACIZE9_001382"
     CDS             13452..13613
                     /locus_tag="ACIZE9_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HGC6093251.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERIKAVMVNETARKAINLHIVNL
                     RREIRRLEE"
     gene            13616..13915
                     /locus_tag="ACIZE9_001383"
     CDS             13616..13915
                     /locus_tag="ACIZE9_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093252.1"
                     /translation="MGKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPKRK
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            13915..14229
                     /locus_tag="ACIZE9_001384"
     CDS             13915..14229
                     /locus_tag="ACIZE9_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HGC6093253.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKAKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILNEYFE
                     ED"
     gene            14406..14717
                     /locus_tag="ACIZE9_001385"
     CDS             14406..14717
                     /locus_tag="ACIZE9_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HGC6093254.1"
                     /translation="MDELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            14714..14932
                     /locus_tag="ACIZE9_001386"
     CDS             14714..14932
                     /locus_tag="ACIZE9_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HGC6093255.1"
                     /translation="MISLTIFWCVIGGLLAMLGAYLIYESAKGKKYTAVGIILFVVGI
                     LVAIGAEINLYLNGTTEELMWFLLWTRR"
     gene            14945..15226
                     /locus_tag="ACIZE9_001387"
     CDS             14945..15226
                     /locus_tag="ACIZE9_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093256.1"
                     /translation="MGDMGEYWKDIKPHLKERRKQHVRKMGNSATKNIETLGFEFTHY
                     PNNHQFAINTHNGIIDYWGTTGTWIERKTKKRGKGIRSLRKYINQEDSK"
     gene            15223..15549
                     /locus_tag="ACIZE9_001388"
     CDS             15223..15549
                     /locus_tag="ACIZE9_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093257.1"
                     /translation="MNYTQQELTDLCPKHVAEFINNEVLPKYADGLNTAENVTDFMIN
                     DAIDRLIFLEIDCIAYYRLHAEVALIDPYIALSQNRKILVAYIDTKQILEGRDVEIEI
                     DEEEVG"
     gene            15546..15743
                     /locus_tag="ACIZE9_001389"
     CDS             15546..15743
                     /locus_tag="ACIZE9_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093258.1"
                     /translation="MKAYTIKFYGNKTYVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEAE"
     gene            15740..15949
                     /locus_tag="ACIZE9_001390"
     CDS             15740..15949
                     /locus_tag="ACIZE9_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093259.1"
                     /translation="MKIYVVKFGNKFYRSDERSIGANTLFIVDILQSARWFDSLEEAN
                     QVSRRLGGLTQVYELVTVDHEEVER"
     gene            15946..16233
                     /locus_tag="ACIZE9_001391"
     CDS             15946..16233
                     /locus_tag="ACIZE9_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093260.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKKRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMKAI"
     gene            complement(16266..16517)
                     /locus_tag="ACIZE9_001392"
     CDS             complement(16266..16517)
                     /locus_tag="ACIZE9_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093261.1"
                     /translation="MTMWSMLLFWIPVCIGIVAFCYFVKHSRTNKLLMLSFLPIVFFI
                     VQIVKYTYIESQEIFIFYVVGLFISVVFFIMILSYFYKK"
     gene            16825..17292
                     /locus_tag="ACIZE9_001393"
     CDS             16825..17292
                     /locus_tag="ACIZE9_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HGC6093262.1"
                     /translation="MVLFDVKKYETPEAKDVDMDRTKHNVGVFLSAYLSARCRIGQPR
                     EPKVTASYSLVPPSTANNTFEAERMMIEREEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            17591..17932
                     /locus_tag="ACIZE9_001394"
     CDS             17591..17932
                     /locus_tag="ACIZE9_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093263.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDPRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(17925..18116)
                     /locus_tag="ACIZE9_001395"
     CDS             complement(17925..18116)
                     /locus_tag="ACIZE9_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HGC6093264.1"
                     /translation="MVKNLYFVIREATNGQYYFVIKSDNNEVVATSETYLTKYSAEQT
                     INSIKNGITKDSQVIDVTK"
     gene            18466..18678
                     /locus_tag="ACIZE9_001396"
     CDS             18466..18678
                     /locus_tag="ACIZE9_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093265.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQAKYFYDQL
                     ILQGFNDAQAMEFMMRTFSASNQQKE"
     gene            18685..18909
                     /locus_tag="ACIZE9_001397"
     CDS             18685..18909
                     /locus_tag="ACIZE9_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093266.1"
                     /translation="MRNYWYVSLSNKYPQPNADDPIRVVQSVQIKKKYSIIEMTREAT
                     PKEIDKYNLRYCGHGYFSEQNIQTNIERYC"
     gene            18936..19469
                     /locus_tag="ACIZE9_001398"
     CDS             18936..19469
                     /locus_tag="ACIZE9_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HGC6093267.1"
                     /translation="MVNLTPKQKAFADEYIKNGGNATQAAIKAGYSKRSARVIGKENL
                     TKPNIIQYINERLNPIEKKRKLSAEDALNELIDIWQGEVQISVSKQIDRLEKNKVIKH
                     MQYEYTPDLESKLKALDLYLKYKSLLSQTQLEKAQTEIKLMQAKLEQLQINSERSTEE
                     KLDELLEKISGELDGTS"
     gene            19456..20700
                     /locus_tag="ACIZE9_001399"
     CDS             19456..20700
                     /locus_tag="ACIZE9_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HGC6093268.1"
                     /translation="MALVDIYNPKQIDVLNKTIKNDWFITLLHGAKRSGKTKINNDLF
                     LFELRRVRKIADEEDIKEPMYILAGVSSATIQKNILQELYNMYSIEPKFDKHGNFKLF
                     GVKVVQAYTGNIGGVGAIRGMTAYGAYINEASLARQEVFAEIVSRCSGTGARILADTN
                     PDNPEHWLKKEYIDNSSKNIQSFHFELDDNTFLSERYRNNIKESTPSGMFYDRDIKGL
                     WVSAEGVVYRDFDASKHYIQSKDLPPLSNFYCGVDWGYEHWGSIVVIGETDDGTAYLI
                     EEHATQFEEIDYWVDVAKGIQERYGLRVPFYCDSARPEHVARFVREKINAKNAHKARL
                     SGVEEVAKRFKQDKLFICQDRVMKFRDEIYQYIWDKKKGEPIKEYDDVLDSVRYAIYT
                     HELLKKPKVNVNEKIKRIKRMF"
     gene            20713..22212
                     /locus_tag="ACIZE9_001400"
     CDS             20713..22212
                     /locus_tag="ACIZE9_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0046798 - viral portal complex [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0051027 - DNA transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGC6093269.1"
                     /translation="MDKVNEFEYGADIHYSNDVNTNYVKFSVDSNLHYRFSSAEDLLN
                     DLDTLAAMIKHHHEYQVKRLSVLDDYYKARNTNIMDNRRRREKEKADHRSAHNFGKVL
                     CTFDVGYNTGNPIKVQIEDTNQQKEIEEFNTNNDIDGLNAELWLDMDKYGRAYEIIYR
                     DSDDTDYVDLANVFETFVVYDTTVKREPILAVRYPKTRFNKDADKQYIQPIVYTKEKS
                     ITYDETTLTAIELKNPQDEPHEYKEVPITEYSPNRFRMGLYEDVLSLIDLYDAGQSDT
                     ANYMTDLNDALLVISGDIEAAGLSTEDAIKQKEANMLLLESGTDVNGNKTSVTAGYIY
                     KQYDVNGVEAYKYRVRKDIHEISMVPDLTDDNFSGVQSGEAMKYKLFGFEQMTATKQR
                     LFKKGLMRRYRLLFSLKSSISEMDNSDLKGLRVIFTPNLPKAILEELKSLVDAGAELS
                     QETILGLASFVPDVQAELKRVNKETQKQIGIFDSDGEEVINNKKDETGG"
     gene            22217..23143
                     /locus_tag="ACIZE9_001401"
     CDS             22217..23143
                     /locus_tag="ACIZE9_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HGC6093270.1"
                     /translation="MNSQEYWIKREKEWQKQQIKDDKKRMAEIKSRMQYAQDAIQKEI
                     DAQWDSFSNGQKITRSEAMKRASEMDVKAFARKAKKYVKEKDFSPTANQELKLYNLTM
                     RVNRLELLKANIGLELISLFNELDKYFSNELTKAGLAELKRQAGILEMTIASSGYAKL
                     IELVINSSFLSDDVSFSDRLWMYQSELKSELDRLLVRSITMGKNPKQLASKLAEYLTA
                     EGRENTKFNTQRLMVTETTRVQVGIQERSYRDAGITQYIYIAEPTACKLCIPLNNQVF
                     DVADMQPGSNAPNMHPFCRCSTAPYIERISSR"
     gene            23270..23872
                     /locus_tag="ACIZE9_001402"
     CDS             23270..23872
                     /locus_tag="ACIZE9_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HGC6093271.1"
                     /translation="MKKRLFMPMNLQFFSEPGDGGSGDEGQQGNLPAGSQETPPEAKE
                     ENNTGKTFSRDEVAKMIAAETNKAKAAWEKELAAKKEEAKKLAKMNAEEKLQHELEQK
                     EAEIAELKRGQALSEMTKEASKMLTDANLPHDDDLLGLIVSDDADATKQAVAVITNFA
                     SLIKRENARQTPPNEGGQFTASKNTKETVAKLAAKNRIIK"
     gene            23885..24808
                     /locus_tag="ACIZE9_001403"
     CDS             23885..24808
                     /locus_tag="ACIZE9_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGC6093272.1"
                     /translation="MKKKQLLPMNLQMFAQTWDPDNVLVYETKEGKIPDKYNTLILSE
                     VMENSKIMQLAKYEEMTDKEKKFEYFAEGPGAYWVGEGEKIKTSKPKWMQATMTAKKL
                     GVILPVSREYLNYKLSDFFEEMQPKIAEAFYKKFDAAALLNKENPFPQSLDGSVISAG
                     NVVEGGLTYDNILALEDKLAENEFEPNAFISNRKNRTELRSAAQTVGSNVEFIYDRST
                     NTIDGLPVVDLKSLDKGTLYAGDFNYMFYGIPYNISFKISEEAQLSTLTNEDGTPVNL
                     FEQELIALRATMDVGFMIVKDEAFGKISPKA"
     gene            24826..25089
                     /locus_tag="ACIZE9_001404"
     CDS             24826..25089
                     /locus_tag="ACIZE9_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093273.1"
                     /translation="MPNQKTWTGKVGDTKTFTISAVPADASDAAAVVAATTATSSDGA
                     IATVTKNENGGFDGTIAAEGSATFTFTSGEFTTSINVTGQPAS"
     gene            25101..25430
                     /locus_tag="ACIZE9_001405"
     CDS             25101..25430
                     /locus_tag="ACIZE9_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HGC6093274.1"
                     /translation="MMIADDIKKLLKGTIDEKLEVIERRTNERMKTLLNTQEVPKEFE
                     TVVYEVSLKRFNRIGQEGMQSYSQEGLSMAFPDSDFSEYQNEIDEFKRKDQEELYKPK
                     RGRFKFV"
     gene            25427..25753
                     /locus_tag="ACIZE9_001406"
     CDS             25427..25753
                     /locus_tag="ACIZE9_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093275.1"
                     /translation="MRFTDEIIFVKRSSDSKYDPDLGEWVEGKPERTRTEANVTDIGT
                     DRSVTIFGSVEEGAKVIRTQPLFSIPTFDYIEIEGKTWQQKTARNPAYRNSLIVQEVV
                     LDEGTT"
     gene            25737..26075
                     /locus_tag="ACIZE9_001407"
     CDS             25737..26075
                     /locus_tag="ACIZE9_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HGC6093276.1"
                     /translation="MKAQLEYKGIDQLMRHLKKAATLNDVQKVVKSNTAEMTERMQKG
                     APVDTGYLRRSINMNLLEAGLTGIVGPTADYAPYVEYGTRFMSAQPYVRPAFNYQKVK
                     FMAEMKALVK"
     gene            26075..26467
                     /locus_tag="ACIZE9_001408"
     CDS             26075..26467
                     /locus_tag="ACIZE9_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HGC6093277.1"
                     /translation="MIKTRDQSIFDELFKISQNKLGYKTYDYKTLEDVGYPFVEFENT
                     QTIHEVNKTDIKGSVIVVLSVWGLQKKRKQLSDMASALFNEARLIEATEGYYWALNYQ
                     ASGIQVMDDTTTNTPLKRAVVTLEFRIR"
     gene            26478..26990
                     /locus_tag="ACIZE9_001409"
     CDS             26478..26990
                     /locus_tag="ACIZE9_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HGC6093278.1"
                     /translation="MEALKGIDVILLYRLLKKETQEAAWKMAFQTEHENGLSRDSDST
                     VTKDGNVQSLSPVEYDFSATSIVAKGDSHVDEMKQALLNGDIIEIWEINKAEQGTDDN
                     ANKYKATYYQAYVSEFTPSAAAEDNVELSLSFAVNGVGQDGYATLTEDQADVVQYAFK
                     DTVKATSTGA"
     gene            27036..27404
                     /locus_tag="ACIZE9_001410"
     CDS             27036..27404
                     /locus_tag="ACIZE9_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HGC6093279.1"
                     /translation="MKLKIKGKEYSFKFGTKFVRELDKVMPFVDGNMEFGMGLSAKVL
                     PELRSYNVNTLSRVLEIANRTEDESITLDELDDYIDEVKDIEKLFDEVLKELAESNAG
                     KLAVRNLNQKLKEAEKQQVE"
     gene            27458..27745
                     /locus_tag="ACIZE9_001411"
     CDS             27458..27745
                     /locus_tag="ACIZE9_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093280.1"
                     /translation="MTNISDIERMTLYEYNIRMTAAQLSWLDKEKLIHELAWANQQVQ
                     AEKKVGKKTVPVYRSFEEFFNYQKIEDSIMGVSELSKQDKKFQSLLTKANS"
     gene            27762..30881
                     /locus_tag="ACIZE9_001412"
     CDS             27762..30881
                     /locus_tag="ACIZE9_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HGC6093281.1"
                     /translation="MEQFSVEALLKATDSGFVKTFKDAQDAVKTFEKNSNSMTTAVGK
                     VMQGTGAAMTKYITTPLIGVGVAAAKVGGDFEAQMSRVKAISGATGDTFEQMKQQAID
                     LGAKTAFSAKESAAGMENLASAGFSAQEIMKAMPGLLDLAAVSGGDVALASENTATAL
                     RGFGLEASEAGHVADVFARAAADTNAEVGDMGEALKYVAPVANSMGISLEETAAAIGI
                     MSDAGIKGSQAGTTLRGALSRLARPTKAMQDTMDNLGVSFYDADGKMKPLKTQVELLK
                     KAFEGLTPEQQQNALVTLYGQESLSGMMALIDKGPDSLGKLTKSLKDSDGAADDMART
                     MQDNMNSSIEQMFGAFESAAIVIQKILAPSIKKVADAISGLVEKFVSAPESTQKLVVA
                     IGAIVAAIGPLIFMIGSVIIWINRVKVAFKALSESSKLFSGLSKAMGLLTNPVFLVIA
                     AVALLVVGFIYLWNTSEDFRNFWIGLWEGIKSAVSSAVEWIQNAWKSTGEWFNNLWKS
                     IKEGADNVWTTVQEAPGKAADWIKNKWTGTKEFFSNLWSSIANSASEIWNSLKEGVIS
                     VIDDLVSSAGEKWEGFKNTISTAWKTITSKIKSGFDFILKYIGPFVSSFSDVFSNIVK
                     AITSIFAEVKNIIVNAWEIIKSLIAAPLLFIIDLITGDFEQMKEDLDLIWNTLVQSVV
                     NIWTSVKNIFTEYIGAIVNSAVSLWTGFIQSISNIWNEVVYQATMIWIDLKLFFTNLW
                     IDIKYSAIQMWINLKFSIIQTWIDTKYGAIELWNNLKQWFFQTVNNIVQTLIKSWNSL
                     KQGTIDLFNNTVQGAKDIWTSFKSWIGDLITGTKDNIIQGWENLKQGTIDTFNNLVNG
                     AQEAWDNLVNAVSDTVDRVTGWFDNLKNIDLLAAGKAIMDSFLEGLQNAWKSVQDFVG
                     GIGDWIREHKGPIQYDRKLLIPAGQAIMNGLNKGLTGGFNDVQNTVGSMADFIAELFN
                     ANSDVDIAANLKNANKNIGAQVEHKINMGGSTKPAVFKINLGRQSFRLFMDDISQAMG
                     EGADINLEF"
     gene            30893..31681
                     /locus_tag="ACIZE9_001413"
     CDS             30893..31681
                     /locus_tag="ACIZE9_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="distal tail protein Dit"
                     /protein_id="HGC6093282.1"
                     /translation="MDQRENKMYSFKDTTINLTSSKRFLPTSAMMYDGMYLEDLIDGY
                     QTLTVEGREMLSVEVEQQEIQIGSIITNQKIPSRTLKITYKLEDRDPEKLQFKFKELL
                     NYLYRNEDVEIRFHDELDYYYYGRYTSTDTVPGDSNSIISSFNVFCADPLKYTKECVS
                     DGYIGNPIQFPITPRKIEVTLSMNNSIKITNGEQNITITDAAIKTGDVLVFDFSDEQV
                     TVNGEDCTSMIDLESDFENFYLKQGQKITSNNGKLKIFYRGATI"
     gene            31678..34509
                     /locus_tag="ACIZE9_001414"
     CDS             31678..34509
                     /locus_tag="ACIZE9_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HGC6093283.1"
                     /translation="MSETVYFFDHLQKLIKRKNTRSLIEVSQEKEISSDKSDLMKDTL
                     YVTTKYDKEIEDARYMAIRENESSFSLYRITKVSDPFETLEFTGLGFATNELDAYIIK
                     DIRPSGQPLKNVLDRLIEFTEGNWRVGHVEAMLPTVTATFYYVSVKEALKELQTLGME
                     FVFRCSLNSDGIKDKWIEVYEQIGEESNTRFVYGSKALTVVREIDRSSISTSMIGRGR
                     GEEVGDGYGRRIEFTDVEWKKSNGDPLDKPKGQNWLEDPESTQKYGIPQKDGSMRKRE
                     TVVVFDDIDDPTDLLKNTYSTLIDSARPLVQFKAEVTGGDVIGNTVTIHRYDKGYHYK
                     TRIYKTTFNRLTGQTNIELGDNLTQDVRKQTASIVNNINSLESSKMTFYESTEIGKYQ
                     DDIMRGAGDNGGSIYWVNGIEAGVSDSREIYETVYMDGPNIPRSRFFMVQNNSGISFK
                     QCKKGEWQTIQDVHNGDSTTAWTLDGTFNANFIRAGILSGILVQGVALKTFDDKDFQL
                     VAEGGELSFEKQVKSTGLDDVHGERLGSIVSTYGSKGINGFAVWKEPNYIFSINAGDG
                     GDRGNPIFQIPADVTADKRKYNLYGDGNFSEGNITIDGRLDVKELYVNGTKIDTNGGG
                     NSGGNDNGWNGQYPPEVTTDRDKRYWQIWATAIGAGFTQQAAAALLGNAQGESDANPT
                     ADEGNGAPGFGYGVWQWTDSSGATSGRVYMINLMTKAGISDDPDTITAQFKLLMWHAP
                     NGQWIATSAYPYTWTQFMNLTDINTAAQAFVANFERPRDPHPERTAWSQEWYDKFKDL
                     EIPVSKGYMKPIADPITVTSEFGWRTSPITGAQEFHNGIDLVNGNPNTPIFASADGEV
                     IVAGDANYFDWYGNWTVIKHADGMYTGYAHQSRVDVSKGQKVTAGQQIGLMGTTGPST
                     GEHLHFQFMDEFYPSSSGHFHNARDYIDF"
     gene            34484..36241
                     /locus_tag="ACIZE9_001415"
     CDS             34484..36241
                     /locus_tag="ACIZE9_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HGC6093284.1"
                     /translation="MQETTSISKGGIVMAETQHKMVLSTTEPNNGINLVRIRQGDVLT
                     QKFVVEVVEHGKLKTFEGLVPFFINTTKFGENQPVEQKVQEYSPAQARLVYTLSEPDW
                     QWGGENTAHFSFRSLNGDGTWSEQFSTQDFTYRVISGISRSQLRDSGYVWTFEDLLRK
                     FKDYMDQGKNDWEQWLEDNREILENIDPGGMIINILNEAKGDYESLADRLNQKYQVPV
                     GSSQIRETTRFFDYDTMKYVDLVPRNLNTVVNSVNNSKFNFSFITDIHADNHNLRIDG
                     VGYKDASYLRHWRAIPQFQKLGNKTDVMIYGGDNIDGGLGSLGSDIGIIDEWSARHSM
                     LGTLKRFTNAAVAGQEKPVIICKGNHDACFDPAWRKRKGMLCNADFEEYWNGLYGGVL
                     FPDKNAAIYRFDTCDFYEGGTGDKYVDGYSDTAPGAFSAKQINAFGEWLVNVPRNYHV
                     ALVGHTPLGLSKFPVRNENMISTLIEGFKSGSPVTIDWSKLGQPNDGSFGGLKTFAMN
                     TKGAGVVVGYFCGHWHEQVEGAFGTVKMILCDVGFSHTASQVDTPDELAFYKIEVDTA
                     TRKVTSKGVGRARDFTYNY"
     gene            36258..37040
                     /locus_tag="ACIZE9_001416"
     CDS             36258..37040
                     /locus_tag="ACIZE9_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093285.1"
                     /translation="MLDFQSKPNIFEEMSYEEAVKWLLRQAAIHYDGSDHDAHVLATE
                     SNAGFATPETVMQARGRWLRDYKLPQKYPNILDIPPGKYATKAGWGADNPDGIEDDSF
                     VEMMVFADHDSRKLIVAFARYSGEIYIKMTHNSEPVEGYNSLGWRRVYTTSVLFEGEL
                     RKGQSVNLPDDTFRYQTLRIHYTDGDGDFVEEVKRQRYARITKANLWNGDAGVTFIEF
                     ELTIEARKITMSNGRALDISSGNVSNPAMSNNVKITKIEGVK"
     gene            37040..39226
                     /locus_tag="ACIZE9_001417"
     CDS             37040..39226
                     /locus_tag="ACIZE9_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HGC6093286.1"
                     /translation="MAHVIKKGSIKVPTQPKDYDLQATGLVFKSYDNQIALEFNVEQQ
                     NGTPADLLGANLRLLMFIYDEVDGMITKEPIPFITKNLITESFLNGQVVYILPEAMKA
                     YNGMVEAYVYIEYPDGSTSDNLGFTFRMKRSAIDGLAQDKADYFIADFQQLLDGVKQE
                     ATDAVNAALTNVDSTIEKANQQINEFVEGATQAIDQTVDEVTEQLQATQTKIDTVSQN
                     VTSAQNNLKAVEDKMNQTNQQIGDLGKLKKMYSNSIDFGNYDYSGNPNLMSKLKSSDF
                     NVGYHGSLTSDNEKLHFTSDGTGSIIMFTRINTPQLASGKTYTLSAKVRFDEGTTGAI
                     DKLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYMSISFV
                     DRDKINGGFKLYDIKIEEGSTATPYQPNLLDDPYWLGKAPLGENIANKSVTFPIKSSA
                     YSLYQANMEEEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRYGNLEPVEGLVDTWG
                     LTFTPQKVGVNYPKRLTIIQYPQSTTGACQIDWLKIEKGDTRTPNISQFKYFGEGLKD
                     SNNPNDYSWDVTPEYTEKGLNDAVNVYDPQRVEGLKNFADGIQIAGDKVISENDCTVY
                     TLTKDNSQSFIDGYATFIKHGKEVIVNGTVKFKKAYAFGVPLDDEVPDEFVAKIVHGM
                     LTGPSGTSSVSKAMYVRKDLGTIITNSEFAANEWFTFHGNYWVGEE"
     gene            39229..39675
                     /locus_tag="ACIZE9_001418"
     CDS             39229..39675
                     /locus_tag="ACIZE9_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093287.1"
                     /translation="MKNIWKYGRTGGEYAGQVLDDMVMTVPFTDVPPLEGIRADGEPL
                     TIADQMFDPKLNQWIVLVNVLDHNDLNNLKAMYESLENENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADGLAQINSKTMLASFQNSKDIAEIKEQLNPASKGGE"
     gene            39677..39814
                     /locus_tag="ACIZE9_001419"
     CDS             39677..39814
                     /locus_tag="ACIZE9_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HGC6093288.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEAEKIINKDKSA
                     S"
     gene            39851..40144
                     /locus_tag="ACIZE9_001420"
     CDS             39851..40144
                     /locus_tag="ACIZE9_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093289.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERSR"
     gene            40167..40364
                     /locus_tag="ACIZE9_001421"
     CDS             40167..40364
                     /locus_tag="ACIZE9_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HGC6093290.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            40375..41394
                     /locus_tag="ACIZE9_001422"
     CDS             40375..41394
                     /locus_tag="ACIZE9_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGC6093291.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGPNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
BASE COUNT        14537 a         6663 c         8604 g        11602 t
ORIGIN      
        1 aaataaaaaa agcgttagca actatgctta aaaagcatat cgactgaata aactaagcat
       61 tggacaggct gaaagactac atttaaaatg aaatgcgaag aaacaataga aaataaagtt
      121 gccttagaac catagttgaa tcacctaaca gtcgtgaagg gagaataaga gaaatggcag
      181 aaaaacaaac cgcaggacga gatcaattag gagattttgc accaaaattt gcagaattga
      241 atgatgatgt tttatttgga caagtatggt ccagagaaga attatctgct catcagcgta
      301 gtatcatcac catatctgca ttaatttcag gaggaaattt tgaacaattg ccagctcatc
      361 tgaagattgg caagcaaaat ggcattacta gtgaagaaat agcagaaatc attacccatt
      421 tagcttttta tgtaggatgg ccaaaagctt ggtcagcttt tagtttagca aaagaaatct
      481 atttagaaga aaatagcgaa gataagaaag aggcgtaaat gacgacaaaa cacgaagaaa
      541 tacacaatgg cgtgattttt ccagcaggtg aaaaaaacga agcttacgct caagtattta
      601 ccgggcaaag ctatctgaat atgttagtga atgatcccga agtttctgtt ggtgtaggta
      661 atgtaatttt tgaaccaggt tgtcgcaatc actggcatgt ccataaagac ggctatcaaa
      721 tcttacttgt gaccggagga gaaggctggt atcaggaaga aggaaagcca gcaagacgat
      781 taatggctgg agatgtcgtc gtaacgcaca aagggattaa acattggcat ggtgcgacaa
      841 aagacagttg gtttgaacat ttggcgatca ctgctggtaa ttcagagttt ttagaacctg
      901 taacagatga agtgtatgaa ggattggaaa atcaataatg tcaagcttga acagctcctg
      961 aaagtagatt ttaatcgaac tttcaggagc tgcttttttg attcagtctt ttataaatag
     1021 aaaatagggt taataatagg aatgagaagc acgtcgaaag atcttaatat tgataatcgg
     1081 ctgggcatac atgatttcca cgtcatcaat caaactacct aacagatgat aatcttcccg
     1141 atcatgtcgg ggattaccta atagttcttg atagtagatt tccatactag ggtcccgagg
     1201 attgttcagc aaatcagcaa gtacatctaa atcttctggc tgagtttctg ccgtaccctg
     1261 tatctctatg aaaagccctt cctcagcaaa ttctactcca atacgtattt cagttatttc
     1321 atgggaatat aaataagtaa gaagctcatc gatgattctt tttgataatt ctttttccaa
     1381 gtgtcttttt ttcctttctg acagcggtaa agttatctag tatcggtaca aggatacctg
     1441 caacgaaacc agttgaaaaa ccactgttat atagatttag tcctccgtgc aaagtgctga
     1501 cgttatggac aagagcaata tgtagtacac cagctattac accgtaaaaa ctgccgtaaa
     1561 aaccgcttat gggcgcgaga cctgtcccaa acacagctgc aacaagcatg ccagtactgg
     1621 tgatctcatg aaaagttcca aacaaagaag caataaatat tccgactagt atcggaaaac
     1681 tgttttttaa atgacaacca aaagcactga aacccaccgc agataaaata gcaccgatga
     1741 caggtccatt taactgaccg ccaaccagca aaacataaga agacagcatc agaccaacta
     1801 agcctatgtt gatcaaagta gcaccaatac cagaattagc aatgaaatca gttgtcaatt
     1861 ttccagatga atcgaaaatt tctcgaatcc ccaaaagccg aaaggaatta taatagaaac
     1921 caattccgac tgtcagcgaa aaaaagccaa aaataatcca aatgagagga aagtgatatt
     1981 cattgaaaac caatgtattt tcgacgattg aatagctgaa taacctcaaa acagcagtaa
     2041 aagtcatcgc aatcaaccca gaggtgaatc caatattata aagtgtgaat ccacgatgga
     2101 aaactaaagt ttgagcagct aagggcggaa gaagtagacc aattgctatg ccagctaaat
     2161 tccccaataa aatacctatc agtaaaggaa aacgcatacc aaaagtgata taactaacga
     2221 ccggtgataa tgcgctacca aacagtccga tcatgatgta ctgagaaaaa ggtttattga
     2281 caaatacagc gtatagatac acacctaaaa tgattgagat agaattataa aggtttttgc
     2341 caaaaaaaga gaaaccggta actgttagaa tcgaagcaaa taagggaccg tttaaaatca
     2401 ccttgtgccg ataagctaaa agcacagaaa gtaaggtcaa aatccctaca tttatgaatg
     2461 cgcttccgaa accgcctaaa gcaaaataat ctgtcaaaag attgcttggc gaggtaagaa
     2521 tagttagcaa tccactccaa ttatcagtag gagtattaga aagcaagcca ataaaaagaa
     2581 aaaaaacacc tgtaaaacca agataaaaat actttctttt ctgtgaaacg attcgttttt
     2641 gaggatgaat ataaataacg tcagtttcgt tttccattac acaccttctt tttcattttc
     2701 tttaactata acttgaaatg aaagatttgg acaactatca tttaggtcaa aactaaaaat
     2761 gtaagggaac ccattgaatt taaccaaatt tttttaattt tgcaaaaaaa agttaaagaa
     2821 gactgaaaaa aaatttaaaa tataacgttt tgagtaaaat gtttgcaaaa aatgctaaaa
     2881 atagggtaca ataaaacaac atatactgca gtaaagaagt gggggagttt taatgagaag
     2941 aaaagtctat accaaggatc aaattctaaa agctgcttat gatgttgttg caaaggaagg
     3001 gtttaaagga tttactgcga gaaatattgc taaaaagatg gggatttcga cacagccgat
     3061 ttatctggaa ttcaaaaaca tggaagattt aaaaaatacg ttgctggatt ctatctttga
     3121 acaactaaaa gaagatgttt tccctattga acgtactggt gataaaatca ttgatctcgg
     3181 tttgaactat atctactttg caaaaaagca tcatagtctt tacatggcat tgtacattga
     3241 tgaacatggg gacggaaaga aaatgcatga tttttcatac aattatttcc gtgaaatagt
     3301 taaagaagat gaaagataca atcaattatc ggatgaatat gtcgatgctc tgcatactgg
     3361 tacatgggta gcagtgactg gcttagcgtc attgatgtca tcaaacatca tgcatccaac
     3421 agaagaacaa atcattgcac tgatcaaacg gacaattgac tcgattttag cattagataa
     3481 tcctgaaata atcagatagt gttctatcag tatgaatttg atcggtaagt ccgttggctg
     3541 caaactgtca atggactttt ttgctaaaaa aagcgatttc tgttatttat ctattagaaa
     3601 taggcttgac atttcgtgaa aaaagtttaa aaatagtact tacggaaggt tggcagagtg
     3661 gtaatgcacc ggactcgaaa tccggcgaac cggctaatac cggcgcgcag gttcaaatcc
     3721 tgtaccttcc ttatatatca acgattagac acgatttcga tcgtgtcttt tttgttgtat
     3781 atttagccta aaatgttttt tgactcccct tttgactccc cctgagtact gttcttcata
     3841 aatgctacaa aattattgat gacttttttg ttttgagttt cagttacatg agtgtaaata
     3901 tttgaagtag tttgaatgtc tgcatgccct aaacgttcct gaacatcttt taaagaagct
     3961 cctgattcaa aaaggagaga ggcatgagta tgtcgaaaac catgagtagt gattctttta
     4021 gtcaattctg gatgatgctt atatatgaca ttaagccacg aacgtgaaac tgtagggtta
     4081 tagagaagac catcatggtg aaaaattaag ttttcccttt ggattgtaac gatcgttttg
     4141 ttttttgtat aatactttct caataaactg atcaaatcat tgtccagata aatttttctt
     4201 tttccagatt ttgatttagg agtatttacg atcaatcttc cttgataacc tcttgttaca
     4261 gttttattga tattgagtgt tttgctctta aagtcaatat ccgaccaggt cagagcaaaa
     4321 gcttctcctt ttcttatacc tgtaaaagcc aatagggaaa agaataaata tctttcatca
     4381 tcatcgtttc ttattgcttc taaaaatttg attaattctt ctttagtata aaattcgata
     4441 tttttatctt cgatatctag agcttctcca cgtggaatag aaactaattt cataggattg
     4501 ctagttataa tttgtaaaga agcagcgtaa tcaaaaacat tagatgtgta attttttatt
     4561 ttcttaaaaa ttttaggatg gctatcggac caagtgttta ctgcttcttg acagaaaaaa
     4621 acgtctattt tgtcaatgaa cttatctcca aacactttta agatgtgtgt gtcaaaaatt
     4681 tgtttggtgg aggaccaagt gctttcttta actgtctttt tataattttc aaaccataag
     4741 ccgtaaacat attcgaattt cttgctcttt tgagctgtag aagcttgcag tcctttttcc
     4801 tgtatatctg cctccaatct ttttaaagct ctctcagcgg ctaatggcgt actaaaacct
     4861 cgtctcgttg tttttctttt ttttcctgtt agaggatcaa ctcctaagta cagactaaac
     4921 tgatattttt cttcgccttt ttttgttaag tgctttttaa ttcgtttatc aatttctttt
     4981 tttgccatct ttatctttcc tttcgtacgt ttgttcggtt gtacagcgga tttcgagatg
     5041 gtaaaatagg gtacaacaaa tagacctact ttaccgtagc tctttgcaca tttgcgttct
     5101 tggtcgggcg gcaaatgtgc tttttttatt tcactcttag ttcttgtcct ggataaagca
     5161 tgtagttgtt tggatccata ccgtttaatg caaacagttg atctaccgta attccagctc
     5221 gttcagctat ttgtttggtc ccttcaccag gttgcaaagt caaggtttcg gtttcagatg
     5281 aagaaggtgc cgttggttga gcttgattag ctggtacata atcttgtggt actgattgct
     5341 ccgttgaact gggagtgggt gaaacttgtt caacacttga actaggagta gcttctgcat
     5401 agttttctac actttcagca gagtaagtac tactagtttc aggaggcgta ttctgcgcaa
     5461 tagcagcttg ttctacagta ctagaagatg caatagtact ttctgttgta gtcgaagatg
     5521 attgttcgtt gctacttgtt gagctagtag ttgttctaga ttctttagtt tttttccttt
     5581 ttgtagggtt tcaaaactaa tttctcatta tcatcagatt tgttaggctt ttctggagtt
     5641 aaaataatat ttttatcttc tttgctgaca gtatatttgg catcattatc tttgtcttta
     5701 tcatctttcc aagtcataac atcgccttca agtgtatact caaatttgta attcatttgg
     5761 tcgactaagc ttttagcaaa ttcttctccc atagcctccc aatcgttact tgaagttgat
     5821 ttcatagaac ttgtgtcaac actaaaagat acgacgtgat cagaaaatga tacgatcata
     5881 ttaggttcgt catctttggt tgcttcaatc aaccaatcat tagcttttaa atcttctgta
     5941 gttacttttt taccacaagc agtgaaaagt aacagagaag caaaaactaa taaacttgtt
     6001 attacttttt tcatttttta ttcctcattt ctatgatatg atttttattg gggaatctta
     6061 gaaataaggt ttcgagtccg tgttgctgca cgggcttttt ttatttaaat aaatcccaaa
     6121 aactgaatgt agttttcttg tatactttat tgtaagcagc cttttttggg tctttaatcc
     6181 agccgctacc ttttttccca taaccaggaa taactgcttt ttttactttt ctttttgctt
     6241 ttccagtggt tctagcgctt atggattttt ttatacttgg ttttctcatt cctattttca
     6301 tctatatcct ccttacgttg tattataatt cacaagaaac gatcgaattc atctggtaat
     6361 ccaaagcaga cgagcttttc atattttgtc atatgatcaa agccgtctaa agttggatca
     6421 atagtcagat gagttgcgaa ataatttgct tctttttcaa tttttaattc agatactagc
     6481 gtttttttag acaacatagg tgtgttttca ttcggatgca aaacacagtg gcctaattca
     6541 tgactacaag ttatccattt tcccatctca tctaaactag aatttatgtg gatcattttt
     6601 atctgtttga atttactata gtaaccataa atttctccca aatcttcttc taaaactagt
     6661 atcttcaatt ctcgtgcaat tctaaaagga ttgcgtgttt gatatagttt taccagctta
     6721 ttaattttgt tatcaatttg aggtaaatac ataaacaacg tactcctttt aatcgcgata
     6781 ttttttaggt gtgtattttt tcttagcttc tattttagct attcgcaaag cattctctaa
     6841 agaaataatg agagcttcac gtgtcgcttc actcatttca ttatctttct tcgaaaaagc
     6901 cattccatca gcattagata aatcgtcgat taatgactgc aattcttttt ggatatcacg
     6961 ctcgtctttt tctgttaaat catagtatct ttttttctca gtacgtccta gcaaataatc
     7021 tacagatacg tcgaagtagt cagcaatttc ttgtaacttt tcggcagttg gctgttttcc
     7081 tgcgtttaaa ctataaaagt aattctctcc gtacttcaaa tctttagcga cttgttgaag
     7141 gtttttattc ttgtttttcg ctagttcttt tattctttca aatgttgtca ttccaacgtt
     7201 cctttccaac acgaaaaaat aatttacgaa aaagagtaaa aatagcttta caattttacg
     7261 atatagagtt attatttatc cgtaagttaa tttgatagaa aaaagcaaac taaaaacaca
     7321 ccttatagca taaagtttgg cgaccaagtg caaataaaag gttttgttat aggcttattt
     7381 ctctatgtat tcattttact ctatagtgta aaaatgtcaa tggaaattat attttttcta
     7441 tcattttaac ttacaaattt ataaaaaaag gaagtgggtt aatgtcaaac ttggataacg
     7501 gtcgtgcggc gatcaaagag tttatgaaag agaatggaat aactatggat gatttggcta
     7561 ctgcttatgg tcacacgcgt gtacgaatgc aacaaattct tgatggacac tggagtggac
     7621 caaaggcaaa cagaactatt ctagagatca tccgtgatta cagaattcga taggaggcaa
     7681 gtcatgaata ttctaagcga agagtttttg actcgtttaa gaattgcaat tgttgaagtt
     7741 gtaaaggacg cacttagtca actttcaaaa aagaatttgt cagaaacacg atatttaaaa
     7801 aagatcgaag ctagaaaata tgtgggaggt gtaaacgatc aaggttttga gaagttaata
     7861 gctcacggtt taaaagaaat tcgtatagat ggctttttaa gatatgacaa aaaggacatc
     7921 gatgaactga tggctaaata caaaatttaa aggaggtcaa catgggaaag tttaatcgaa
     7981 cattagtatt cagcgcgcca ctaattatct acgctttagg tctatggggt agtagacaag
     8041 cattaatcgg cacgatcgtt tacatgcttt ggattttcat tgggcttgat gaagctgagt
     8101 acagagcgaa aaagccagtc gggagggact gactaaaaaa gtctaatgtc tataagaaag
     8161 gtttgacaat aaatgaaaga attatttttt ttaataactt tcatcatttt ttctatcagt
     8221 gttttctaca ttaacctttg cgttgctaga tttgctttga aaagttttag gaacagcaaa
     8281 cgaaaataga gctataaaag atacgaatgt agtagctacg ttaaattgct ctttagaaaa
     8341 cgtcaatgtc attggaatga taattgatat cgatgagaaa atctttgcga taataactat
     8401 ccatttttca attataaaca tttttaaatt aagcaccatt agacaaaatg tagttcctat
     8461 atagaggata aatgaagata gaaataaaca tattagtcca gttttaaaaa aagagaagta
     8521 atctatgtgg gcaaattctg ttaatatgct tttttgattt aacacaatca aactactgtt
     8581 ggacaaaaat gacagtaagg aaagagttgc tccgattact aaataaaaaa tagttgttaa
     8641 caatattata ttatcaattt ttctgctcat gttttcaccc caccagaatt atatcaaaaa
     8701 ggagagaaga aataatgcaa gaattagtaa ttttgaaaaa taaagaagct gtgactacga
     8761 gcttacaagt tgcagaaagc ttcgataaaa agcacagaca tgttttgacg gctattgatg
     8821 aactaaaaga gggggttgcc gaaaattggg cagacctatt ttgggaagat acttatgttc
     8881 atcctcaaaa taaacaatca taccgaatta tttatatgaa tagagacggc ttctctctat
     8941 tagcaatggg cttcactggt aagaaagctt taagttttaa acttcaatat attgaggcct
     9001 tcaacaagat ggaaaaagaa ttaaaagacc aattgccatc aattccagca actaaacgag
     9061 aaatggcatt acttgctcta gctgcaaacg aagaaacgaa tgaaagagta gacgctatcg
     9121 agtctgattt aaacgatttg aagaacaatc aacttctagc tgaaccagat taccgaacaa
     9181 tttctaatat ggttcgcaac aaaattagag ttatttgtaa tcagcagcat ttaaatagca
     9241 aagcaaaagc agaattgttt aaagacttga atggcggaat taagcgaatc actggagcag
     9301 tagctagaaa tcgtatcaag gcaaaacagt tcgatgatgt tatcgatttt attaacaatt
     9361 ggatgccttc tacagcgacg atgacaatta ttaagcaaat ggagttgtta gaggatgaat
     9421 agagctgaag cgctaaaaat aggcgtaata attgctaatc gctggtggag acacaataaa
     9481 ccaaacatcc taagccaaca acatattgat aagcaaaaag catggcaaca aataaaaaag
     9541 tgactcagcc gaccaaagca atgagtcaca aagaaaatac atctaaggag atgttaccac
     9601 atgaaaaaag aactttccac tctagatcaa tatttgactg atcctagttg gggcaaatcg
     9661 aatatcaagg aaacaagcaa tcgaaaaatc agacgtaatc ttttgacgga tgaagaacta
     9721 gcatgtgatc aagacgattt gggaaatttt gtgagtattt gggatcatgt ctatcttatc
     9781 catttatcga ggaagtccaa aaaaactgaa tatatctatg tcatcgaaga tggcttgatt
     9841 gatgcgctag aagagtatga cagagataac ttgattgata tctcttatta cggatcaggt
     9901 aagaaataca ttgctgaaat ggaggcagaa tttgatgagt gaaaaggaac aacctttgaa
     9961 aaatagaagt gataatacgc tttttaatac cttatacaaa ataaatgtga aagatgttac
    10021 tgaaaaacga aataacctca cttatctttc gtgggcatgg gcttgggcag aagttagcaa
    10081 agtgtgtgag gcagtagatt atgaaatcta tcatgatcca gaaacatatc tgccgtatgt
    10141 ctttgataag aaaacaggct atatggtttt taccagtatc acagtcaacg gagtaaagcg
    10201 tgacatgtgg ttaccagtca tggatggtgc aaacaaggca atgaaagatg agccatatac
    10261 ctacgaagtc aatgattatc agtggaataa cgaaacgaag aaaaaagaga ttgttggaaa
    10321 aatcgaaaag cgagttgaag cagcaactat gtttgatatc aacaaaacga tcatgcgctg
    10381 tcttgtaaaa aatctagcaa tgtttgggct agggctatat atatttgctg gcgaagatat
    10441 gccagaagat gtctcgatgc ttgaaccagc tactcaaaga agcaaaaagc tattcttgga
    10501 tgctttacaa ctggttgcta acaagtacga aaaatcaatt gatgaagcaa ttgttgcatt
    10561 gactgatgcg gcttctataa ccgctgatga cagtaaatgg accaagagag acttgggcat
    10621 tctaaaacga ggcgttaact ggattgaaga tcagtacaga gaagaaacaa aagagaagtg
    10681 atatgagtgt ttaaaccatt gatcgattca tattcagcgg ttctgaaaaa gttcaaagga
    10741 aaagacatag gtgcaacgat caatgaagaa gtgaacattg atcgactaaa gacgatgtat
    10801 gacggatatg atggcgatcg gattattgaa gttcgattta ttgatccacg tcgatttact
    10861 gtgcagcaac gaaacttcat ctatgcgctg ataggcgata ttttcatcga tacaggcatg
    10921 ccaacggact tctggaagga attcttttac ttccgttttg aaggcgtcac agggcgcaaa
    10981 ataagcctca aagacgaatc gaatacaact gtgagtgatg ctaatgtctt agcaaatatc
    11041 atcttagatt tcatctttga acatcatatt cctttcaaag aaggctatga gattttacca
    11101 gcgaatcaag aatattactt ctacaaatgc atcacaaaaa gagtctgctg catctgtggc
    11161 aaaacaggag ctgacatcga tcactttgac aaagcgctag gaagacgaaa gcgcaaagaa
    11221 gttgatcatt cagagtacac atttgcagca ctctgcagga ttcatcacac ggagaaacac
    11281 aatataggtg tgatcaattt caaaaataaa tatcaaatca aagggatcaa gttaaaccag
    11341 gaaacaatta agaaacttag aataggaggg taaaaaatat tgtctgacaa caaacgctac
    11401 tactatttaa aactaaaaga gaattttttc gatagtgacg agatggttct cttagaaagt
    11461 atgccagatg gctatattta ttctaatatt cttctcaaac tttatttaag aagtctaaaa
    11521 cacgaaggta agttgatgtt taatgacagg attccattta actctacaat gctcgcaact
    11581 attacaagac attctgtagg agtcgtagaa aaagcggtac aaattttccg tgatttgcag
    11641 cttattgacg tattagataa cggagcaatt tatatgtctg atatacaaag tttcattgga
    11701 aaatcctcaa ctgaagcaga tagaaaaaga gaatacagaa agaaaataga agaggcaaaa
    11761 cggaatttaa taactggagg acaagtgtcg gacaaatgtc cagacaaaac tacaccagag
    11821 ttagagatag agatagagaa agatatagat atagataaag aagaaaagaa aggtaagtat
    11881 tctgacgaac acttacgcct tgctaaaaaa ttgcaaagta atttaactga agattttcca
    11941 aaagaaatga acaaagtaga tatcgaaaaa tgggcagaca caatcaggtt gatggaagaa
    12001 agagataaag cgtctataga agcgattgag tatgtgatca attggctacc tacaaatgaa
    12061 ttttggtttg gaaatattag aagtgctaag aaattgagag aaaaatttga gaagctcaaa
    12121 ttcgaaatca aagcagacaa gaataatcat aaaaagcaaa gtcaaaaact acagtacagc
    12181 aatcctagtg aatatgacga cttgccaatt taaaaaggag atgcatcaca tggaaagcct
    12241 agcaaatgct atggagaaac taataagaag agtattagtg caaagcggga aatgtccaga
    12301 atgtagcgaa cctttgtata gttggcgagc taaaaataag gatggttcag aacgttgtaa
    12361 accaacatgc atgagttgtg gttataaagc gttacgtgtg aaagaggata tacagaccga
    12421 acggatatat aacgacagct taaaagcacg agcgttgagt ttttttcaaa atggttcggt
    12481 attaacagat aaaactttgt ttaaatgcaa aatggagaat tatcacgtag tggaccaaga
    12541 aacgaaaatt gctttagaaa gagctaaaag ctttgtaaat gatgtcttac tgaaccatcc
    12601 tgcacatttc attctatcag ggaaatcagg aagcggaaaa agccacttgt caatggcgac
    12661 agcttgggaa atacttgagc gctcaaatta tgacaagaaa atacttttta taagctatca
    12721 agagttatta gagcaaataa agttttctta taacaatgct gaactgagaa aagaaattga
    12781 aggatcgctt atagccgata tcaaaacaac tgatttggtg gtttttgacg atattggagc
    12841 tgaattaggt agcggggtat caaatagtag gcagtttaca aacaacacgt taaacacgct
    12901 cttagaagcc agacagaaca aggcaacgat catcacaaca aacttatccg gtcctgaact
    12961 aagagaagcc tacggcgaaa gaattgtttc tagaatattt aagaattcag aaggttatgc
    13021 gctgaaattc caacaaacag cagacaagcg cataaaacca gtgaaaggta gtatcgcatg
    13081 aataaatacc gtaataagaa aactgttcat cgaggtatca agtttgattc tatcgcggaa
    13141 gcagagtatt acgatttagc cttgtggcaa gcagaagcga acggctggaa agtaaaactt
    13201 caggaaagat ttgagctgat gccgaaattt gaactagatg gaaaaaagta tcgcaagatc
    13261 gagtatattc ccgacttcac attttataaa aacggcaaac ttgtcaaagt cgtagatgtc
    13321 aaaggaatgc agacaaaaga ctttaagatc aaggcaaagt tgttctgtca tcaatatcaa
    13381 gtgccgttga tattagctaa aaaatatcgg aatacgttca aggaagagcg tttttaacga
    13441 ggtggtccat catgacaaca gaagaagtga ttcaaatgcg tattcgaagc cttcaacgtg
    13501 agattgacga tctggaacgg ataaaggcag tgatggtcaa tgaaacggcg agaaaggcaa
    13561 tcaatttgca catagtgaat ttaagaaggg aaattcgtag attggaggaa tgagcgtggg
    13621 taagaaagca gcaatgaaac gaatcattga actgacacat tctgagaatt ggcaagaaga
    13681 caaagaaata gttgcagaag tccaaaagct cggtaaatca atgtggactg aaaagcctaa
    13741 acggaaaacg ccgagaaaaa ttgcaatctg gcatggtgat cgaattctag taacgggtac
    13801 agctgaacag ttatctgaaa ttactggact gagcaaaaac atcatctggg atagagctag
    13861 gagcttatgg attgattcaa aggggcgaca gtttaggtat gtggaggaga aataatggat
    13921 ctcattacac aatacagtga tatcatcctc aagaaaatca tgatgaagat tcagaaagat
    13981 aaaaaagcaa aagaacgagc ggaattagtt aagttggaaa tggctgaaac aggagcagga
    14041 gtgcgaagta gcaggcattg gaaagcagca gcaaacattg aattttatta caacgaaatt
    14101 caaaaagggt tcgatcagat gcgtgagctg gatcggcaaa caaattggag caagaaactt
    14161 catcaggatc gtttcaaatt tgtagaaaag tatagagaga tactgaatga gtatttcgag
    14221 gaggactaga tgtttaattc aacgttagcg tcaattcact ttttattcta tataacgata
    14281 tttgtagcta tattaattaa tgcgataaaa agcggttttt taacaccaat cggcacaatt
    14341 ttaacattag cttcatttgt tacaagttgt attatccaac ttaaatatat aaaggagaat
    14401 gaataatgga cgaactaatc acaaaagtag agcagtgggc taaagataag ggattggatc
    14461 aagctgattc cagcaagcaa atgttaaaaa cgatcgaaga gatcggggaa gttgccgctt
    14521 ctctagctag aaaagatgaa catggtttaa gagacggaat tggagatgta gtagtaacct
    14581 tgattatttt agctatgcaa aatgatatgg atttgtacga gtgtctgaac caagcataca
    14641 acgaaatcaa aggacgcaca ggaaaaatgg tagatggtgt attcgtgaag tcgagtgatt
    14701 tggaggacag caaatgatca gcctaacaat attttggtgt gtaattggcg gcttactagc
    14761 gatgttagga gcatacctca tttacgagag tgcaaaaggc aaaaaatata cagcagtagg
    14821 gattattttg tttgttgtcg gaattttagt tgcgattggt gcagaaataa atctttattt
    14881 aaacggtacg acagaagagt tgatgtggtt tttattgtgg acaaggagat aggaggacag
    14941 cgaaatgggc gatatgggcg aatactggaa agatattaaa ccgcatctaa aagaacgtag
    15001 aaaacaacat gtcagaaaga tgggcaattc agcaactaaa aatattgaaa ccttgggatt
    15061 tgaatttact cattatccaa acaatcatca atttgcaatt aatacccata atggaattat
    15121 tgactactgg ggaactacag gaacgtggat tgagcgcaaa acaaaaaaac gtggtaaagg
    15181 gatacgtagt ttgaggaaat atattaatca ggaggacagc aaatgaacta tacacaacaa
    15241 gaactgactg atttatgtcc aaaacatgta gctgagttca tcaataatga agtcctgcct
    15301 aaatatgcag atggtttaaa tacagcagaa aacgttacag attttatgat taatgatgct
    15361 attgatcgtt tgatattttt agaaatagat tgtattgctt attatcgtct acacgcagaa
    15421 gttgctttga ttgatccgta tattgcttta agccaaaatc gaaaaatact cgtagcctat
    15481 attgatacca aacagatttt agaaggcaga gatgtcgaga tagagatcga tgaggaggaa
    15541 gtgggatgaa agcatacaca atcaagtttt atggaaataa aacctatgta tacatcctaa
    15601 gcggtctcag acttgatttt agaggctatt caaaagaaga ccttttagaa tccttatatg
    15661 gttacggata tttaaatgaa gatgaactaa taagcttaga gaaatttaca aatgcttgga
    15721 cgattgagga ggaagcagaa tgaagattta tgtagtaaag ttcgggaata aattttatag
    15781 aagtgatgaa cgctctatag gggctaacac attattcatt gtagacatac tccaaagtgc
    15841 gagatggttt gatagcctcg aagaagctaa ccaagtttca cgacgacttg gtggattaac
    15901 acaagtatat gaactggtca ctgtcgatca tgaggaggta gaaagatgaa attaaaagac
    15961 ggattttacg ctagtagtca tggtatcggc ggtttaatgc tagatatgcc gacaaagaat
    16021 cctaaaaaac gtaagaaacc aaaattcaaa gtcggtgaca tggttcgctg cgaagcagaa
    16081 gggttcatct atccatttcg tggatatgta gaacacgtct ataatcactc agcgatcatt
    16141 cgtattgaaa acacgatgga atgtgataag tggttagcga aaagcaaaga gaatttagct
    16201 gtagcgagat tggtggatat gaaggctata taaacagcga aaaaatgtac ttctaagaga
    16261 aaaatttatt ttttataaaa ataggaaagt atcattatga aaaagaccac agagataaat
    16321 aaacctacca cataaaaaat gaatatttct tgcgattcaa tataggtata tttaacaatt
    16381 tgtacaataa aaaatactat aggtaaaaaa gataacatga ggagcttatt tgttctagag
    16441 tgtttgacaa agtaacaaaa tgcgacgata ccaatacaaa cgggaatcca aaataacagc
    16501 atgctccaca tagtcactca accatctcct atacgcttta ttatcaatag ataatatcat
    16561 ttttcgtaat aaagataaaa aaataagtaa ggcttctcat taaaatataa aaaagacagc
    16621 cgaccactgg ctgtccttag cagaatattg aaatagtgag ccatctgttt tccgccagat
    16681 agctcaacat gtatatgggt aacgagtgca acctcgctac ttgaaaagct tagcataagc
    16741 atgggtataa aaaaagccgg attcctccga ccttaattaa taattctgac acaattatta
    16801 tatcataaat ggaggaatca atggatggta cttttcgatg taaagaagta tgagacacca
    16861 gaggcaaaag atgtggatat ggatcgcaca aaacataatg ttggtgtttt tctttcagca
    16921 tatctgtcag ctagatgtag gataggtcaa cctcgggagc ctaaagtaac ggcatcttac
    16981 tccttggttc caccttctac agcaaataat acatttgaag cagaacgaat gatgattgag
    17041 agagaggaag cgcaagaaga atttgagtac ttgcacaaat tatttgttcg tggctattca
    17101 gcaattcagc atccgcataa acctgatgta acagaaaggc gcaagaagat attctatgat
    17161 cgttatatca atggtctgcc catttatgta actgctcaaa ggaataatac tagcgaagaa
    17221 tcggttaaag tagaatcaaa cagaattatc atccaatttg cttcatcgtt agaactggtt
    17281 gcttttaagt agccagtttt tacacttttt ataccctttg attacccatt tggtttccat
    17341 tttatacctt ttttatacca atcacttacc tggtaaatga tttattatga tagtgtcgaa
    17401 agattagtga taggtctgag acaaaataat aataaaagga acatcgtttt attattgttt
    17461 cacaattaag cttcgataga cagcaacgga aatattaaga ataaggatgt gaattccaac
    17521 tccttctaaa ttgttcttat tatctatcat ccgttgctgt ttattaattt atgtattgga
    17581 gggaaaacga atggaagtcg agcaaataaa gtatcaaggt atggatcggg aacggttgat
    17641 tgatattatt gagcaacaac gtttagaatt gatccaaaaa gaagctgtat gtaaagagta
    17701 caaaaaacat ttagaacaag taattgagta tcattcagta gaaaagtaca gatcagtggt
    17761 gcaaaaaaat agagcaacga gtcctgatcc tcgtcaagat gtatcgatta gtatcaagac
    17821 gccagtattt aattctgtta aatcagaaaa gctagaaagt atctcaactg ctttggtaga
    17881 aaaagcagct gaaatgaact ccctagcaaa tgaagttagt cgtcttattt agtcacatcg
    17941 ataacttgag agtctttggt gattccgttt tttatagaat taatggtttg ttcagcggaa
    18001 tatttagtca agtatgtttc gctagttgct actacttcat tgttatcgga cttaataacg
    18061 aagtaatatt ggccattagt tgcttctctt ataacaaagt acaaattttt caccaccttt
    18121 taatttattt cagcggacca ctcgctgata aataaaatta tacacttagt atttattttc
    18181 acaatattaa tttgtcactg tggcggaaag ggtagacgct aagcatgtgt gttaggtcaa
    18241 tgcttcggca accatgcaag gttcgattcc ttgccagtga ctttggcaac tgagggttgg
    18301 aaatgggcgc tcaaagtaca cgagcaaggc gaggtcgata gtaatcgatg gaatcggtgt
    18361 aggttgcttg atagaactat aactgcatct cgtttatgag gtgtagtttt tacatattag
    18421 atcactcatc gagtggtctt tttattttgg aaggggagta aaaaaatgaa cgaaaaccaa
    18481 ttaagagagt tgtttaaaac gaatgaagca aacaaaacaa tggaggcgac attctacgaa
    18541 actcaaaaaa gcttagcgtt aatcgcaaaa caagctaagt atttctacga tcagcttatt
    18601 ctgcaaggat ttaatgacgc acaggctatg gaatttatga tgcgaacctt ttctgccagt
    18661 aaccaacaga aagagtgata cgtaatgagg aactactggt atgtatcatt atcaaataaa
    18721 tatccgcaac caaacgcaga tgatccaatt agagttgtcc agtcagtcca gattaaaaag
    18781 aagtactcca tcattgaaat gaccagagaa gctacgccaa aagagattga taagtacaat
    18841 cttcgttact gcggccatgg atattttagt gagcagaaca tacagacaaa tattgagaga
    18901 tattgttaat aaaattgaaa ggtggtggct tgaatgtggt aaatttgaca ccaaaacaaa
    18961 aagcttttgc ggatgaatat ataaaaaatg gtggtaatgc tactcaagcc gccattaaag
    19021 caggttatag caaacgatca gcaagagtaa taggtaagga aaacctaact aaacctaaca
    19081 taatacagta tattaatgaa cggctaaatc ctatcgaaaa gaagcgcaaa ttaagtgccg
    19141 aggacgcttt aaatgaattg atagatattt ggcaaggaga agtacaaata agcgtgagca
    19201 agcaaataga ccgcttggag aaaaacaagg ttattaaaca tatgcaatat gaatatacac
    19261 cagatttaga aagcaaattg aaagccttgg atttgtattt gaagtataaa tcgctgttat
    19321 cacaaacgca attagaaaaa gctcaaacag aaataaaatt aatgcaagca aaattagaac
    19381 aattacagat aaactcagag cgttctaccg aagaaaaact tgatgagttg ttagaaaaga
    19441 ttagtggtga attagatggc actagttgat atttataacc caaagcaaat cgacgtgtta
    19501 aataaaacca ttaagaatga ttggtttatt actttattac atggagcaaa acgttctgga
    19561 aaaacaaaaa taaacaatga tttgttcttg tttgaattgc gacgtgtgcg aaagattgcc
    19621 gatgaagaag acattaagga accaatgtat atcctagcag gagtttcaag tgcaacaatc
    19681 caaaagaaca tcttacagga actatacaac atgtacagca tagaacctaa attcgataaa
    19741 catggaaact ttaagctatt tggcgttaag gtcgtacaag cttatacagg aaacattggc
    19801 ggtgttggcg caattcgtgg tatgacagca tatggcgctt atatcaatga ggcatcgcta
    19861 gctagacaag aagtatttgc tgaaatcgtt tcacgttgtt caggaacagg agcgagaata
    19921 ctagctgata caaaccctga caacccggaa cactggctaa agaaagagta tatcgacaat
    19981 tcaagcaaaa atattcaatc gttccacttt gaattagatg ataatacatt tttatctgaa
    20041 cgatatcgta acaatattaa agaatcaaca ccaagcggca tgttttatga tcgtgatatc
    20101 aaaggtttat gggtttctgc agaaggtgtc gtttatcgtg attttgatgc tagcaagcac
    20161 tacatccagt caaaagactt accacctttg agcaactttt attgtggtgt tgactgggga
    20221 tatgaacact ggggttcaat cgtagttata ggtgaaacgg atgacggaac agcttattta
    20281 atcgaagaac atgctactca atttgaagag attgattatt gggtagatgt ggcaaaaggc
    20341 attcaagagc gttacggctt acgagtacct ttttattgtg actctgcgag accggagcat
    20401 gtggctaggt ttgtaagaga aaagattaat gctaaaaatg ctcataaagc acggttatct
    20461 ggagttgagg aagtcgccaa gagatttaaa caagataaat tgtttatctg tcaagataga
    20521 gtgatgaaat ttcgggatga aatttatcaa tacatttggg acaagaaaaa aggcgagcca
    20581 ataaaagaat atgatgatgt gctagactcc gttcgatatg cgatatatac tcatgagctt
    20641 cttaagaaac caaaagttaa tgtcaacgaa aagattaaac gtattaaacg catgttttaa
    20701 ggagtgtgaa aaatggataa ggtaaacgag tttgaatacg gagctgatat acattattct
    20761 aatgacgtga acacaaatta tgtaaagttt agcgtagact caaatcttca ctatagattt
    20821 agctcagcag aagatttact taacgattta gatactttag cagcaatgat aaaacatcat
    20881 catgaatatc aggtaaaaag gctaagtgta ttagatgatt attataaagc tagaaataca
    20941 aatatcatgg ataaccgtag gcgcagagaa aaagaaaaag cggatcaccg atcagcacat
    21001 aactttggaa aagttctttg tacgtttgat gttgggtaca acacaggcaa tcctataaaa
    21061 gtgcaaatcg aggacacaaa tcaacaaaaa gaaatcgaag agtttaatac taataatgac
    21121 atagatgggt taaatgctga actctggctt gatatggata agtatgggag agcctatgag
    21181 attatctatc gagattcaga tgatacagat tatgttgatt tggctaatgt atttgaaacg
    21241 tttgttgtat atgatactac agtaaaacga gagcctattt tggctgtacg gtatcctaag
    21301 acaagattca acaaggatgc tgataaacag tacattcaac caatcgtata cacaaaagaa
    21361 aaaagtatca cttatgatga gacgacacta acagcaattg agttaaagaa tccccaggat
    21421 gaaccgcatg aatataaaga ggtacctatt acagagtatt ctcctaatcg ttttcggatg
    21481 ggcttgtatg aagatgtact atctttgatt gatctatacg atgcagggca gtctgatacc
    21541 gccaattata tgactgatct aaacgatgct cttctagtta ttagtggtga tattgaagca
    21601 gcaggactat ccacagagga cgccatcaag cagaaagaag cgaatatgct tttgcttgag
    21661 tctggaactg atgtgaacgg taataaaaca agtgtgactg caggatatat ttacaaacaa
    21721 tatgatgtga acggtgtaga agcatacaaa tacagagtac gcaaggatat tcacgaaata
    21781 tccatggttc ctgatcttac tgatgacaat ttttccggag tgcaatcggg agaagcaatg
    21841 aaatataaat tatttggatt tgaacaaatg acggcaacaa agcaaaggct attcaaaaaa
    21901 ggccttatgc ggcgttatcg tcttttattt agcctaaaat caagtatttc tgaaatggat
    21961 aactccgatt tgaaaggctt acgtgtaata tttacgccta atctacctaa agccattctg
    22021 gaagagttga aatctttggt tgatgctgga gctgaactca gtcaagagac gatcttagga
    22081 ctcgcttctt ttgttccaga tgtacaggca gagttgaaac gagtaaataa agaaacgcaa
    22141 aagcagattg gcatttttga ttcagatggt gaagaagtaa ttaacaacaa aaaagatgaa
    22201 acaggggggt gattaaatga actcccaaga atattggatc aaacgggaaa aggaatggca
    22261 aaagcaacaa attaaagatg ataaaaagcg catggcagaa attaaaagtc gcatgcaata
    22321 cgcacaagat gcgatacaaa aagaaataga cgcgcagtgg gacagtttct ccaatggcca
    22381 gaaaatcact cgtagcgaag cgatgaagcg tgctagtgaa atggatgtca aagcattcgc
    22441 tcgcaaagca aagaagtatg tcaaagagaa agatttttct cctacagcaa accaagaatt
    22501 aaagctatac aatcttacga tgcgtgtaaa tagattagag ctcttaaaag ctaatatcgg
    22561 gcttgaattg atttcactgt ttaatgaatt ggataagtac ttttcgaatg aattaacaaa
    22621 agctggttta gctgaattga agagacaagc cggtatttta gaaatgacta ttgcttcaag
    22681 tggatatgca aagctgatag aactagtaat aaacagctcc tttttgagtg atgacgtgtc
    22741 ttttagtgat cgcttatgga tgtatcaatc tgaattgaaa tcagaattag ataggttgtt
    22801 agtcagaagt ataacgatgg ggaaaaatcc caagcaactt gcatctaaat tggcagaata
    22861 tttaacagct gaaggacgag aaaacactaa gttcaacact caacgtttga tggtgactga
    22921 aacgactaga gttcaggtag ggattcaaga acgaagttat agagatgcag gcattaccca
    22981 gtacatctat atagcagaac caacggcgtg caaactatgt ataccgttaa ataatcaagt
    23041 ttttgatgtt gccgatatgc agccaggaag taacgctcct aatatgcatc cattttgtcg
    23101 atgcagtaca gcaccttata tagaacgaat atcaagccgt taacacaaat taacggcttt
    23161 ttattgtgcc ttcttacagc ttacaggcgt taaagagaaa gctattttcg gctgaccggc
    23221 gtaactggtc aaatttatcg ggtagcggcg taaccgtgga ggattaatca tgaaaaaacg
    23281 tttatttatg ccaatgaact tacaattttt ttctgaacca ggagatggtg gatctggtga
    23341 tgagggacaa caaggaaacc taccagctgg ctcacaagag acaccgcccg aagcaaaaga
    23401 agaaaacaat actggcaaaa cattttctcg tgatgaagta gcgaaaatga tcgctgctga
    23461 gacgaataaa gcaaaagcag cgtgggaaaa agaactagca gcaaaaaaag aagaagctaa
    23521 aaagctggca aaaatgaatg cggaagaaaa actacagcat gagttggagc aaaaagaagc
    23581 tgaaatcgct gaattaaagc gtggacaggc actatctgaa atgacgaaag aagcttctaa
    23641 aatgctgaca gatgcaaatt taccacacga tgatgattta cttggtctga ttgtttctga
    23701 tgatgcagat gccacaaaac aagctgtagc agtcatcact aactttgctt ctttgattaa
    23761 gagagaaaac gcaagacaaa caccaccaaa tgaaggtgga caatttacag catcgaaaaa
    23821 tactaaagaa acagtggcta aactagctgc taaaaatcga attatcaaat aggaggaaaa
    23881 cttaatgaaa aagaaacaac ttttaccaat gaacttgcaa atgtttgctc aaacatggga
    23941 tccagataat gtcttggtat atgaaacgaa agagggaaaa attcctgata aatataatac
    24001 gctcattttg agtgaagtta tggaaaattc taagatcatg cagttagcaa aatacgaaga
    24061 aatgactgac aaagaaaaga aatttgaata ctttgcagaa ggaccaggcg catactgggt
    24121 gggtgaaggt gaaaaaatta aaacgtctaa acctaaatgg atgcaagcta cgatgactgc
    24181 aaaaaaactc ggtgtcattc ttccggtttc tcgtgaatat ttaaattata aattatcaga
    24241 tttctttgag gagatgcagc caaaaattgc tgaagctttc tataaaaaat ttgatgcagc
    24301 tgccttatta aataaagaaa acccatttcc tcagtcacta gacggatcag ttattagtgc
    24361 ggggaatgtg gttgaaggcg gattgactta tgataatatc ctagccttag aagacaagtt
    24421 agcagaaaat gaattcgaac ctaatgcgtt tatttcaaac cgaaaaaatc gtacagaatt
    24481 acgttctgca gctcaaacag tcgggtcaaa tgttgagttt atttatgatc gctctactaa
    24541 tacaattgac ggattaccag tagtagacct taagtcttta gataaaggaa cactttacgc
    24601 tggagacttt aattacatgt tttatgggat cccatataat atttcattta agatttctga
    24661 agaagcccaa ttgtctactt taactaatga agatggaacc ccagttaact tgtttgagca
    24721 agaactgatt gctttgcgtg caacaatgga tgttggattt atgattgtaa aagatgaagc
    24781 atttgggaag atttccccaa aagcgtaacg cctgctaccg gtattgtgcc aaatcaaaag
    24841 acatggaccg gtaaagtagg cgatactaaa acatttacta tttcagctgt gcctgcagat
    24901 gctagcgatg cagctgctgt tgttgcagct actacagcaa cttcaagtga tggagctatc
    24961 gcaacagtga ccaaaaatga aaatggtggt tttgatggaa cgattgcagc agaagggtca
    25021 gcaacattca catttacttc tggagaattc actacttcaa tcaatgtgac aggtcaacct
    25081 gctagttagg aagtaaaaat atgatgattg cagatgatat taaaaaactt cttaaaggaa
    25141 caatagatga aaagcttgaa gttattgagc gaagaacgaa tgagcgtatg aaaaccttgt
    25201 taaatacgca agaagttcct aaagaatttg aaacagttgt atatgaagta tcgttgaaaa
    25261 gattcaatag aattggtcaa gaaggtatgc agtcatattc tcaagaaggt ttatctatgg
    25321 cttttcctga ctcggatttt tcagagtatc aaaatgagat tgatgaattt aagcgtaaag
    25381 atcaggaaga gttgtacaag ccaaagcgag ggaggtttaa atttgtatga gatttacaga
    25441 tgaaattata tttgttaaac gttcatctga ctctaaatat gatccagatc tcggtgagtg
    25501 ggttgaaggc aaaccagaaa gaacaagaac agaggcaaac gtgacagata ttggcactga
    25561 tagaagtgtg actatttttg gtagtgtgga agaaggggcg aaggtcatta ggacgcagcc
    25621 tcttttttct atccctacat ttgactatat cgagattgaa ggaaagactt ggcaacaaaa
    25681 aacagctaga aatccagcat atagaaatag tttaattgtg caagaggtgg ttcttgatga
    25741 aggcacaact tgaatataaa ggaatcgatc agctgatgcg acatctgaaa aaagcagcaa
    25801 cgcttaatga cgttcaaaaa gtcgtgaaaa gtaatactgc tgaaatgact gaacgaatgc
    25861 aaaaaggtgc gccagtggat acaggttact tacgaagatc aataaacatg aatcttttag
    25921 aagctggttt aactggtatt gtaggaccga cagcagatta tgcaccttat gtagaatatg
    25981 gcactcgatt tatgtcggca cagccttatg ttagaccagc gtttaattac caaaaagtca
    26041 aatttatggc tgaaatgaaa gccttggtga aatgatgatt aagacaagag atcaatcaat
    26101 ttttgatgaa ctttttaaaa tatcccaaaa caaacttgga tataaaacat acgattacaa
    26161 aactttagag gatgttggtt atccttttgt ggaatttgag aacactcaga caatccatga
    26221 agtaaataaa actgacatta aagggtctgt gattgtggtt ttatccgttt ggggattaca
    26281 gaagaaacga aagcagttgt cagatatggc atctgctctt tttaatgaag ctagattgat
    26341 agaagccaca gaaggctatt attgggcttt aaattatcaa gcaagtggaa ttcaagtgat
    26401 ggacgacaca acaacgaata caccgctaaa acgggcggtt gtcacacttg aatttagaat
    26461 tagataggag gaagaacatg gaagcattaa aaggtattga tgtcattttg ctttatcgct
    26521 tattgaaaaa agaaactcag gaagccgctt ggaaaatggc atttcaaaca gaacacgaaa
    26581 atggtttatc aagagattca gactctacag tgacaaaaga tggaaacgtt caaagtttaa
    26641 gcccggttga atatgatttt tcggctactt caatagttgc taaaggagat tctcatgtag
    26701 atgaaatgaa acaagcttta ttaaatgggg atatcattga aatttgggaa attaataaag
    26761 cagaacaggg aacagatgat aatgcaaata agtacaaagc tacttattac caagcatatg
    26821 tgtctgaatt tactccatcg gctgctgcag aggataacgt tgaattaagt ttatcatttg
    26881 cagtaaatgg tgttggtcaa gatggttatg caaccttgac agaagatcaa gccgatgttg
    26941 ttcaatatgc attcaaagat accgtgaaag caacttcgac aggagcataa gagggcttag
    27001 atgctctctt ttttatttta ggaggatgaa aaacattgaa attaaaaatt aaaggtaaag
    27061 aatattcgtt taaatttggc actaaatttg tacgtgaatt agataaagtg atgcctttcg
    27121 tcgatggaaa tatggaattt ggaatgggac tctccgcaaa agtcttacca gagctacgtt
    27181 cttataacgt taacacgtta tcacgagttc tggaaatagc aaatagaact gaagatgaat
    27241 ctattacatt agatgaattg gatgattaca tcgatgaagt taaagacatt gaaaaattgt
    27301 ttgatgaagt cctaaaagaa ttggcggagt cgaacgcggg aaagttagcg gtccgaaacc
    27361 tgaatcagaa attgaaagaa gcggaaaaac aacaagtgga atagattctg cactggcata
    27421 cgaacaaatt cttatcaatt cttttcgata tttgggaatg accaatatct cagatatcga
    27481 aagaatgacg ttatatgaat acaacattcg tatgactgca gcccagttat cttggcttga
    27541 caaagaaaag ttgattcacg aattagcgtg ggcaaatcag caagtccaag cggagaaaaa
    27601 agtaggcaaa aagacagttc ctgtatatcg atcctttgaa gaattcttca attatcaaaa
    27661 aatcgaagat tcaatcatgg gagtttccga actttcaaaa caagataaaa aattccaaag
    27721 cttactaact aaagctaact cttgaggaaa ggaggagaat catggaacaa ttttctgttg
    27781 aagccttatt aaaagccaca gatagtggat ttgtaaagac ttttaaagat gcacaagatg
    27841 ctgttaaaac ttttgaaaag aattcaaata gtatgacaac cgctgttggt aaagtgatgc
    27901 aaggtactgg tgccgcaatg acaaagtata ttaccactcc tcttatagga gtaggcgtag
    27961 cagctgctaa agttggtggc gacttcgaag cacaaatgag tcgtgtaaaa gctatatcag
    28021 gagcaaccgg cgacacattc gaacagatga aacagcaagc gattgatcta ggagcaaaaa
    28081 ctgcttttag cgcaaaagaa tcagctgctg gaatggaaaa cttagcttct gctggattta
    28141 gcgcacaaga aatcatgaaa gcaatgccgg gtcttttaga cttagcagct gtatctggag
    28201 gggatgtggc tctagcttct gaaaatactg ctactgcttt gagaggattt ggtttagaag
    28261 caagtgaagc aggacatgtc gctgatgtat ttgctcgtgc tgctgcggat accaatgctg
    28321 aagttggaga catgggagaa gcattgaagt atgttgctcc tgtagctaat tcaatgggga
    28381 tttctttgga agaaactgca gcagctattg gtattatgag tgacgcaggc attaagggtt
    28441 ctcaagcagg tacaacgttg cgaggagcat tgtctaggtt agcaaggcca acaaaggcta
    28501 tgcaagatac aatggataat ttaggtgttt cgttttatga tgctgacggt aaaatgaaac
    28561 ctttaaaaac tcaagtagaa ttacttaaaa aagcttttga aggcctgacg cctgaacaac
    28621 aacaaaatgc tttagtaaca ctatatgggc aagaatcatt atcagggatg atggctttga
    28681 ttgataaagg acctgattca ttgggcaaat taacaaaatc tctgaaagat tctgatggtg
    28741 cagctgacga tatggctcgg accatgcaag ataatatgaa ttcttccatc gagcaaatgt
    28801 ttggagcttt tgagtcagca gctattgtaa ttcaaaagat tctagcacca tccatcaaaa
    28861 aagtagcaga tgccatatcc ggcttagtag aaaaatttgt aagtgctcca gaatcaactc
    28921 aaaaattagt agtggccata ggagcaattg tcgctgctat aggaccgtta atttttatga
    28981 ttggttcagt aattatatgg atcaataggg tgaaagtagc ttttaaagct ttaagtgaaa
    29041 gttcaaaatt gtttagtgga ttaagtaaag caatgggtct tcttacaaat ccggtttttc
    29101 tggttatagc tgcggtagca ctactcgttg taggtttcat ctatctttgg aatacgagtg
    29161 aagattttag aaacttttgg attggcttat gggagggaat caagtctgct gtaagctcgg
    29221 cagtagaatg gattcagaat gcatggaaat ctacaggaga atggtttaac aatttatgga
    29281 agtccattaa agaaggcgca gacaatgttt ggactacagt tcaagaagcc cctgggaaag
    29341 cggcagattg gattaaaaac aaatggactg gaacaaaaga gttcttttca aatttatggt
    29401 caagtattgc aaactctgct tcagagattt ggaatagttt aaaagaaggt gtcatatcag
    29461 ttattgatga tttagtttca agtgctggtg aaaaatggga agggtttaaa aatactatat
    29521 ctactgcatg gaaaacaatt acaagtaaaa tcaaatctgg ttttgatttt atactaaaat
    29581 atattggtcc atttgtaagt agcttttcag atgtgttctc taatatagtg aaagcaataa
    29641 caagtatatt tgctgaggtt aaaaacataa tagtaaatgc ttgggaaatc attaagtctt
    29701 taatagctgc gccactactg tttattatag atttaattac tggtgacttc gaacaaatga
    29761 aagaggattt agatctaatc tggaacacac ttgtccaatc agtggtaaat atttggacat
    29821 ctgtaaaaaa tatatttacg gaatatatcg gtgcaatagt aaatagtgcc gttagtttat
    29881 ggactggatt catacaaagt atttctaata tttggaatga agtagtttat caagcgacta
    29941 tgatttggat tgatttgaaa ctatttttta ctaatttatg gattgatatt aaatacagtg
    30001 caattcaaat gtggataaat ctaaaattct ccataattca aacttggatt gatacaaaat
    30061 atggtgcaat tgaactttgg aataatctaa aacaatggtt tttccaaacg gttaataata
    30121 tcgtgcaaac tcttataaaa agttggaaca gcttaaagca aggaacgata gatttattca
    30181 acaatacagt tcaaggtgct aaagacattt ggacttcatt caaatcttgg attggtgatt
    30241 taattactgg aaccaaagat aacatcattc agggatggga aaacctaaaa caaggtacta
    30301 tagatacttt caacaattta gtaaatggtg ctcaagaggc atgggataat ttagtaaatg
    30361 ctgttagtga cacggttgat agagtaactg gctggtttga taacttgaaa aatatcgatt
    30421 tactagcagc cggaaaagct atcatggata gttttctaga agggttacaa aatgcatgga
    30481 aatctgtgca agattttgtt ggaggtattg gtgattggat tcgtgaacac aaaggaccta
    30541 tccaatacga tagaaagcta ttgattccag ctggtcaggc tattatgaac ggtctgaata
    30601 aaggtctgac aggaggattc aatgacgtac agaatactgt tggaagtatg gcagacttta
    30661 tcgcggaact tttcaatgca aattctgatg tagatatagc tgcaaatttg aaaaatgcaa
    30721 ataaaaacat tggtgcacaa gttgaacata aaataaatat gggtggctct actaaaccag
    30781 ctgtatttaa aatcaatctt ggaagacaat cgtttagatt gtttatggac gatatttcac
    30841 aagctatggg cgaaggtgca gatattaatc tggaatttta ggagggaata ttttggatca
    30901 acgagaaaat aaaatgtact cattcaaaga tacaaccatt aatctcacta gttctaaacg
    30961 attccttccg acgtctgcca tgatgtacga tggaatgtat ttagaagatt tgattgatgg
    31021 ttatcaaaca cttacggtgg aaggtagaga aatgctttct gtagaagttg aacagcaaga
    31081 gatacaaatt ggttcaatca ttacaaatca gaaaatacct tcaagaacac taaaaataac
    31141 atataagctg gaagatagag atccagaaaa actacagttt aaattcaaag aactgttgaa
    31201 ttatttatac cggaatgaag acgtggaaat taggtttcat gatgaattag attattatta
    31261 ctacggtcgc tatacatcaa ctgatactgt tccaggagac tccaactcga ttatttcgag
    31321 ttttaatgta ttctgtgcgg atccactaaa gtatacgaaa gagtgtgtta gtgatggcta
    31381 tattggaaat ccgatacagt ttcctataac accaagaaaa attgaagtta ctttatccat
    31441 gaataattca atcaaaatta caaacggaga acaaaatatc acgataactg acgcggcaat
    31501 aaaaacagga gacgtgttgg tttttgattt ttccgatgag caggtaactg taaacggaga
    31561 agattgtact tctatgattg atttagaaag tgattttgag aacttttatc ttaagcaagg
    31621 tcagaagata actagcaata atgggaagct taaaatattc tatagggggg cgacaatttg
    31681 agtgagacag tttatttctt tgatcacttg caaaaactta ttaaaagaaa aaatacaaga
    31741 agtttgattg aagtctccca agaaaaagaa attagttctg ataagagtga tctaatgaaa
    31801 gatactcttt acgttacgac aaaatatgat aaagaaatag aggatgcaag atatatggcg
    31861 attcgtgaaa acgagtcgtc tttttcgttg tatcgaatta ctaaagttag cgacccattt
    31921 gaaacattag agtttacagg gttaggattt gcgacaaatg aattagatgc ttacatcatc
    31981 aaagatatta ggccgagtgg gcagccctta aaaaatgttc ttgatcgatt gattgaattt
    32041 actgaaggaa attggcgcgt tggtcacgta gaagcaatgt taccaacagt aactgcaact
    32101 ttttactatg tctctgtaaa agaagcgttg aaagaattgc aaaccttagg tatggaattt
    32161 gtctttaggt gttctttgaa ttctgatgga ataaaggata aatggatcga agtatatgaa
    32221 caaattggcg aagaatcgaa tacacgtttc gtatatggta gtaaagcatt aacagttgta
    32281 agagagatag atagaagctc aatctcaact tcaatgatag gtcgtgggcg aggcgaagag
    32341 gttggtgacg gttacggtag aagaattgaa ttcactgatg ttgaatggaa aaagtcgaat
    32401 ggtgatcctt tagataagcc taaaggccaa aattggcttg aagatccgga atcaactcaa
    32461 aagtatggga taccacaaaa agatggatca atgagaaaac gagaaaccgt agtagtgttt
    32521 gatgatatag atgatccaac agatttactt aaaaatactt attcaacctt aatcgattct
    32581 gctagaccgt tagtacaatt caaagctgaa gtcactggag gagatgtgat aggaaataca
    32641 gtgactattc acagatacga taaaggttat cactataaaa ctcgtattta taaaactaca
    32701 ttcaatcggc ttaccggtca aacgaatatc gaactagggg ataatttaac acaagatgtt
    32761 agaaaacaaa cggcttctat tgtcaataat attaatagtt tagaatctag caaaatgaca
    32821 ttttacgaat cgacagagat tggaaaatat caagatgaca ttatgcgagg tgcaggagat
    32881 aatggcggtt ctatttattg ggtaaatgga attgaagctg gtgttagtga tagtagagaa
    32941 atctatgaaa ctgtttatat ggatggacct aacattccta gatcacgctt ttttatggtc
    33001 caaaataact cagggatatc tttcaaacaa tgtaaaaaag gtgagtggca aacaattcaa
    33061 gatgtacaca atggtgatag cacgaccgct tggacgttgg atggaacttt caatgctaat
    33121 tttattcgcg caggcattct gtctggtatc ctcgtgcaag gggtagcttt aaaaacattt
    33181 gacgataaag atttccaatt agtggcagag gggggagaac tttcttttga aaaacaagtc
    33241 aagtctactg gactagatga tgtacatgga gaacgcttgg gctcaattgt atctacttat
    33301 ggttctaaag ggattaacgg ctttgctgtc tggaaagagc caaactatat tttttccatt
    33361 aatgctgggg acggtggcga tcgagggaat cctatttttc aaattccagc agatgttact
    33421 gctgataagc gcaaatataa tctttatggt gacggcaatt tttcagaagg aaatataacc
    33481 atagatggac ggctagatgt aaaagaactc tatgttaacg gtacaaaaat tgacactaat
    33541 ggaggaggca attccggagg gaacgataac ggttggaacg gacaataccc accagaagta
    33601 actactgatc gggataaacg atattggcaa atttgggcaa cggcaatagg tgccggtttt
    33661 acacaacaag ctgctgcagc cttacttgga aatgcacaag gagaatcaga tgctaatcca
    33721 accgctgatg agggcaatgg cgcaccaggg ttcggttatg gtgtatggca atggaccgat
    33781 tcttctggcg caactagcgg acgtgtctac atgatcaatt taatgacaaa ggctggcatc
    33841 agtgatgatc cagacacaat cacggcacag tttaaattgt tgatgtggca tgcaccaaat
    33901 ggtcaatgga tcgcaactag cgcttatcct tacacatgga cacaattcat gaatctgacc
    33961 gatatcaaca cagcagcaca agcattcgtg gctaactttg aacgtccacg tgatccacat
    34021 ccagaacgga cggcatggtc acaagaatgg tatgacaagt tcaaagattt ggaaattcct
    34081 gtatcaaaag gatatatgaa gccgattgcg gatccaatca cagtgacgag cgaatttggc
    34141 tggcgcactt ctccaatcac aggagcacaa gaatttcata acggtattga ccttgtaaat
    34201 ggaaatccta atacacctat ttttgcttca gcggatggcg aagtgattgt tgcaggtgat
    34261 gcaaattact ttgactggta tggaaattgg acagtgatta aacacgctga tggaatgtat
    34321 acaggatacg cgcatcaaag ccgagtagac gtctcaaaag gtcagaaggt aactgctggt
    34381 cagcaaattg gactgatggg gacaacagga ccatccactg gagaacatct tcattttcaa
    34441 tttatggatg agttttatcc atcttcttca ggtcatttcc acaatgcaag agactacatc
    34501 gatttctaaa ggagggatag tcatggcaga aacgcagcat aaaatggtcc tatccaccac
    34561 cgaaccaaac aacggaataa atttggttcg aattcggcaa ggggatgttt taacgcaaaa
    34621 gttcgttgtt gaagtggtgg aacatggcaa actaaaaaca ttcgagggcc tagtgccgtt
    34681 ttttattaat acaacaaaat ttggcgaaaa ccaacctgtt gaacaaaaag tacaagaata
    34741 cagtccagcg caagcaaggc ttgtttacac cttaagtgag cctgactggc aatggggtgg
    34801 tgaaaacacc gcacatttca gtttccgatc acttaatggt gatggaactt ggagtgaaca
    34861 atttagcaca caggatttta cctatcgagt catttctgga atatctagaa gccagttacg
    34921 tgactctggc tatgtgtgga catttgagga tttgctaaga aaattcaaag attacatgga
    34981 tcagggcaaa aatgactggg agcagtggtt agaagataat cgtgaaatac tggaaaatat
    35041 cgatccaggt ggtatgatca ttaacattct gaatgaagct aaaggcgact acgaatcatt
    35101 agctgatcgt ttaaaccaaa aataccaagt gccagtcggc agctcacaaa ttagagaaac
    35161 aacacgcttt tttgattacg acacgatgaa atacgttgac ctagtgccgc gcaatttgaa
    35221 tacggttgtc aacagtgtta ataacagcaa atttaacttt tctttcatta cagacattca
    35281 cgcagataat cacaacttgc gtatagatgg cgtcggttac aaagatgctt cttatttaag
    35341 acattggcgc gcaatccctc aatttcaaaa attagggaac aaaacagatg tgatgattta
    35401 cggcggagac aatatcgacg gcggacttgg ttcactcggc agcgatatag gcattattga
    35461 tgaatggagc gcgcgacatt ccatgttagg cacgctcaaa cgcttcacta acgcagcggt
    35521 agcaggacaa gaaaaaccgg ttattatctg caaagggaat cacgacgctt gtttcgaccc
    35581 cgcgtggcgc aagcgaaagg gaatgttatg caacgctgac ttcgaagagt attggaacgg
    35641 tttgtacggt ggcgtgttgt tcccagataa aaacgcagca atttaccgtt tcgatacttg
    35701 tgatttttat gaaggcggca caggcgacaa gtacgtggac ggttacagcg atacagcgcc
    35761 gggagctttc agtgccaaac aaattaacgc tttcggagaa tggttagtga acgttccgag
    35821 aaactatcat gtggcgttag taggacatac gcctttaggt ctcagcaagt ttcccgttcg
    35881 caatgaaaac atgattagca cgttgataga agggtttaaa tctggtagtc cggtaactat
    35941 cgattggtct aaattaggac aaccgaatga cggttcgttc ggcggattaa agaccttcgc
    36001 aatgaataca aaaggcgccg gcgttgtagt aggttatttc tgcgggcatt ggcacgaaca
    36061 agtcgaaggg gcgtttggaa cagtaaaaat gattctttgc gacgtcggct tctctcatac
    36121 agctagccaa gttgatacac cggatgaatt agcgttttat aaaatagaag ttgacacagc
    36181 aacaagaaaa gtgacaagca aaggcgtagg gcgcgcgaga gacttcactt ataactatta
    36241 aggcggtgaa caattaaatg ttagattttc aaagcaaacc aaatattttt gaagaaatga
    36301 gttatgaaga ggctgtgaaa tggttattgc gtcaagcggc tatccattac gacggctcgg
    36361 atcacgacgc gcacgtccta gctactgaaa gcaacgcggg ctttgctaca ccggaaacag
    36421 ttatgcaagc gcgtgggcgt tggttacgcg attataagct accacaaaaa tatccgaaca
    36481 ttttagacat tccgcccggc aaatacgcaa ccaaagccgg atggggcgca gacaaccctg
    36541 acgggattga agatgacagt tttgttgaaa tgatggtatt cgcggatcac gattcgagaa
    36601 aattaatcgt cgcttttgct cgttatagcg gcgaaattta catcaaaatg acacataaca
    36661 gcgaaccggt agagggttat aactcgttag gctggcggcg cgtttacact acttctgttc
    36721 tttttgaagg cgaattaaga aaaggacaat cagtcaatct gccagatgat actttccgtt
    36781 accaaacgct tcgtatccac tacacagacg gtgacggaga ctttgtagaa gaagtgaaac
    36841 gtcaaagata cgcgcgaatt acaaaagcga atttatggaa tggagacgcg ggagtgacgt
    36901 tcatcgaatt tgagctgaca atcgaagcgc gaaagataac gatgtcaaac ggcagagctt
    36961 tagatatttc atccggcaat gtttccaatc ccgcaatgag caacaacgtg aaaataacta
    37021 agattgaagg tgtgaaataa tggcgcatgt catcaaaaaa ggctctatca aagtacctac
    37081 acagccgaaa gactacgatt tgcaagcaac ggggcttgta tttaaatcat acgataatca
    37141 aatagcgtta gagttcaacg tcgaacaaca gaacggcaca ccggcggact tgctaggagc
    37201 taacttgcgc ttgttgatgt ttatctatga tgaagtagat ggaatgatca cgaaagagcc
    37261 aatccctttt atcacgaaaa acctcatcac tgaaagcttc ttgaatggac aggtcgtata
    37321 tatcttgcca gaagcgatga aagcttataa cggtatggtg gaagcttatg tttacatcga
    37381 gtatccagac ggatcaacaa gtgataactt aggcttcacc ttccgtatga agcgttcagc
    37441 aatcgacgga ctagcgcaag ataaagcaga ctactttatt gcagactttc aacaattact
    37501 tgatggagtc aaacaagaag caacagatgc tgttaacgca gcattaacaa atgtggattc
    37561 tacgattgaa aaggcaaacc aacaaataaa tgaatttgta gagggagcca cacaagcaat
    37621 tgatcaaact gttgacgagg taacagagca actacaagct actcaaacta agattgatac
    37681 cgtttctcaa aacgttacat cggcacaaaa caatcttaaa gcagttgaag acaagatgaa
    37741 tcaaaccaat cagcaaatcg gcgacctcgg caagctgaaa aagatgtaca gtaacagcat
    37801 cgacttcggg aattatgatt atagtgggaa tccgaattta atgtccaaac taaaatcgag
    37861 cgattttaac gttggttacc acgggtcact aacttcggat aacgaaaagc tacattttac
    37921 ttctgatggt acaggaagca ttattatgtt tacgcgtatt aatacacctc agcttgctag
    37981 tgggaaaacc tatactctga gtgcgaaagt tcgatttgat gaaggaacta caggagctat
    38041 tgataaatta cgtttggtgt atcgtacatc accaggagaa aagatattat tggaagcaaa
    38101 tagtacaaat attacaacag atgatgtagg gaaagaaata acaatcaaag gtacagctaa
    38161 cgttaattat caaatcacaa atttagatcg attttatatg agtattagct ttgttgacag
    38221 ggataaaata aatggcggat ttaagttgta cgacatcaaa atcgaagaag gctcaacagc
    38281 caccccatat cagccaaact tacttgatga cccttactgg ctaggtaaag cgcctttggg
    38341 tgagaatatt gctaataagt ctgttacgtt tccaatcaaa tctagcgcct acagcctata
    38401 ccaagctaac atggaagaag aatttgtttt aggtcaaacc tatacaatta ccatgaaggc
    38461 aaccaaacca cctatccaaa cgttcattgt ttacaacgag gatagtggag attatagata
    38521 tggtaactta gagccagtag aagggttagt tgatacatgg ggtctgactt ttacaccgca
    38581 gaaggttgga gttaactacc ccaaacggtt aactattatc cagtatcccc aatcaacaac
    38641 aggtgcatgt caaattgact ggctcaagat cgaaaaaggc gacacacgaa ccccgaatat
    38701 tagtcagttt aaatactttg gtgaaggctt gaaagacagt aacaatccca atgattacag
    38761 ttgggatgtc acacctgaat atactgaaaa aggcttgaat gatgctgtta atgtgtatga
    38821 tcctcagaga gttgaaggtt tgaaaaactt tgccgatggt attcaaatag caggagataa
    38881 agtgatcagt gaaaatgatt gcactgttta tacattaact aaagacaaca gtcaatcgtt
    38941 tatcgatggg tatgcaacat ttattaaaca cggaaaagaa gttattgtaa atggtacagt
    39001 aaagttcaaa aaagcttatg cttttggtgt accacttgat gatgaagtcc cagatgaatt
    39061 tgtcgcaaaa attgttcatg gcatgcttac aggtccgtca ggaacaagta gtgtatcaaa
    39121 agcgatgtac gtgcgaaaag acttaggaac aattattacg aatagcgaat ttgctgcaaa
    39181 tgaatggttt acattccatg gtaattattg ggtaggggag gaataaaaat gaaaaatatt
    39241 tggaaatacg gacgaacagg tggagagtat gctggacaag tgcttgatga tatggttatg
    39301 actgttccat ttaccgatgt tccaccactc gaaggaattc gtgctgatgg ggaaccacta
    39361 acgattgctg atcagatgtt tgatcctaaa ctgaaccaat ggattgtttt agtgaatgta
    39421 ctagatcaca acgatttaaa caatctcaaa gcgatgtatg agtcgttaga aaatgagaac
    39481 ggcgatttaa aacagctcaa cgccaaactc atgctaagcg atgtagcgat taaacaggaa
    39541 aatactgcat tgaaagaaaa agcggatggt ttagcacaaa tcaattcaaa aacgatgctt
    39601 gcttcgttcc aaaatagcaa agacattgca gaaattaaag agcaactaaa tccagcttca
    39661 aagggaggtg agtagtatgt ttagttttag cgatgtgaaa atgatgtatg attggggctg
    39721 ttttactgac gatcaagttc gactattcgt tccactatgc attacagacg aagaagcaga
    39781 aaaaatcatt aataaagata agagcgcatc ttaagtgatg cgtttttatt taaggtaaag
    39841 gagttgtcac atgattaatt taggagaatg gggaacaatc gcaggatcaa tcactgcgat
    39901 tgtttctttg attttattag taataagacc agtcactgca tctttctcga agattactga
    39961 aactctttca aaagtaagtc acaatttaga tttgctgact aaagatttag aatcgagcaa
    40021 atcagatcga ttgatgattc atgaagaact aaagaaacac gatgaaagat tagatacaca
    40081 tacagaaaaa ttggtagaac acacacaaca aatcaaaact ttatttagag aaagatctcg
    40141 gtaaaaaaga aaggagttaa gaagaaatga ttttacccga taagtattat caagtcatta
    40201 aatggacagt tttaacagta ttgccagctg catctgtatt agttgcaaca ctaggcaaag
    40261 cgtatggatg gaatggaaca gatatgacag tactcactat caatgcagta gcaacatttt
    40321 taggcgttat cactggcgtg tcggcttata atttgaaaaa ataggaggaa acaaatgaaa
    40381 aagaaaatta ctattactgc gatgagccta ttaacggctc tttttttatt gccaattaat
    40441 gggtttgcct atacgattaa caatgaattt aatttaggcc caaacgaagg tagctcacaa
    40501 gtagcaaata atcagtacat tttactgcat gaaacggcta atgaaacagc aacaggacgc
    40561 aatgaagcgc agtatatgca acgttcatgg actagcgctt atactgctta tattgtggga
    40621 gacggcggaa ttgtttatca agtcggtcaa cctggttatg tacagtacgg tgctggttcg
    40681 tatgctaatg caaatagtcc tgtgcagatt gagttacaac acacacatga taaagcaacg
    40741 tttgagaaaa actacaaggc atacgttgaa ttagctagag attcagcaat gaaatatggt
    40801 attccactta cactagacac accgtataat caaccaggga tcaaatcgca tttatgggta
    40861 acacaaaata tttggggcga tcatacagat ccttacggtt atctttctga aatgggcgta
    40921 agtaaagaaa aattagccta tgatttggct catggattta ccgatgaaaa tccgacaact
    40981 tcagatgata aaccagtcat tgatccaact cgagcaggtg ctgcaaatcc taccctgaca
    41041 gatggaacaa attacgccca cattgatcag ttcggagaaa tcgaaaacgc aaacttacat
    41101 gtggctggtt ggcacatcgc taactataaa tacgagtata tcttcattat ggattacaat
    41161 actgggaaag aattagctcg agtaaaagct gatggaatat atagaccaga tgtaaatcaa
    41221 gcttataata ctttaggaaa tgttggctat catgtatctt ttaacatgcg caacttccct
    41281 aataagaaag tctatgtaat gatgcgggca acgaatgatc cagaagggaa cactaaaggc
    41341 ggagcacaag attttcatga taaacgctgg tatttaaata ttccgcaacg ataaaaatag
    41401 cccctc
//
LOCUS       DBBGSP010000023        40814 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000023 DBBGSP010000000
VERSION     DBBGSP010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 40814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40814
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.023"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            23..646
                     /locus_tag="ACIZE9_001423"
     CDS             23..646
                     /locus_tag="ACIZE9_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093292.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /gene="trpX"
                     /locus_tag="ACIZE9_001424"
     CDS             1096..2145
                     /gene="trpX"
                     /locus_tag="ACIZE9_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6093293.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="ACIZE9_001425"
     CDS             2142..3023
                     /locus_tag="ACIZE9_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6093294.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="ACIZE9_001426"
     CDS             3026..3796
                     /locus_tag="ACIZE9_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093295.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="ACIZE9_001427"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="ACIZE9_001427"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGC6093296.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="ACIZE9_001428"
     CDS             5107..6270
                     /locus_tag="ACIZE9_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGC6093297.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="ACIZE9_001429"
     CDS             6387..6797
                     /locus_tag="ACIZE9_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6093298.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="ACIZE9_001430"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="ACIZE9_001430"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HGC6093299.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="ACIZE9_001431"
     CDS             9370..9654
                     /locus_tag="ACIZE9_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093300.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="ACIZE9_001432"
     CDS             9814..10050
                     /locus_tag="ACIZE9_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGC6093301.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="ACIZE9_001433"
     CDS             10047..10445
                     /locus_tag="ACIZE9_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGC6093302.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11112..12056)
                     /locus_tag="ACIZE9_001434"
     CDS             complement(11112..12056)
                     /locus_tag="ACIZE9_001434"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGC6093303.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12352..13296)
                     /locus_tag="ACIZE9_001435"
     CDS             complement(12352..13296)
                     /locus_tag="ACIZE9_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGC6093304.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13517..14731
                     /locus_tag="ACIZE9_001436"
     CDS             13517..14731
                     /locus_tag="ACIZE9_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6093305.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14753..16768
                     /locus_tag="ACIZE9_001437"
     CDS             14753..16768
                     /locus_tag="ACIZE9_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HGC6093306.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16851..18224)
                     /locus_tag="ACIZE9_001438"
     CDS             complement(16851..18224)
                     /locus_tag="ACIZE9_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGC6093307.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18250..18534)
                     /locus_tag="ACIZE9_001439"
     CDS             complement(18250..18534)
                     /locus_tag="ACIZE9_001439"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6093308.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18536..20551)
                     /locus_tag="ACIZE9_001440"
     CDS             complement(18536..20551)
                     /locus_tag="ACIZE9_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC6093309.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20730..21035)
                     /locus_tag="ACIZE9_001441"
     CDS             complement(20730..21035)
                     /locus_tag="ACIZE9_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HGC6093310.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21124..22155)
                     /locus_tag="ACIZE9_001442"
     CDS             complement(21124..22155)
                     /locus_tag="ACIZE9_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6093311.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22362..23237
                     /locus_tag="ACIZE9_001443"
     CDS             22362..23237
                     /locus_tag="ACIZE9_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC6093312.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23389..24231)
                     /locus_tag="ACIZE9_001444"
     CDS             complement(23389..24231)
                     /locus_tag="ACIZE9_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC6093313.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24323..26200)
                     /locus_tag="ACIZE9_001445"
     CDS             complement(24323..26200)
                     /locus_tag="ACIZE9_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HGC6093314.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26197..27618)
                     /locus_tag="ACIZE9_001446"
     CDS             complement(26197..27618)
                     /locus_tag="ACIZE9_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HGC6093315.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27621..31010)
                     /locus_tag="ACIZE9_001447"
     CDS             complement(27621..31010)
                     /locus_tag="ACIZE9_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC6093316.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31267..32658
                     /locus_tag="ACIZE9_001448"
     CDS             31267..32658
                     /locus_tag="ACIZE9_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093317.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32731..33378)
                     /locus_tag="ACIZE9_001449"
     CDS             complement(32731..33378)
                     /locus_tag="ACIZE9_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6093318.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33386..34072)
                     /locus_tag="ACIZE9_001450"
     CDS             complement(33386..34072)
                     /locus_tag="ACIZE9_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093319.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34078..35151)
                     /locus_tag="ACIZE9_001451"
     CDS             complement(34078..35151)
                     /locus_tag="ACIZE9_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6093320.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35373..36047
                     /locus_tag="ACIZE9_001452"
     CDS             35373..36047
                     /locus_tag="ACIZE9_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6093321.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36052..37392
                     /locus_tag="ACIZE9_001453"
     CDS             36052..37392
                     /locus_tag="ACIZE9_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGC6093322.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37541..38527)
                     /locus_tag="ACIZE9_001454"
     CDS             complement(37541..38527)
                     /locus_tag="ACIZE9_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HGC6093323.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            39251..40282
                     /locus_tag="ACIZE9_001455"
     CDS             39251..40282
                     /locus_tag="ACIZE9_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6093324.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            40391..>40814
                     /locus_tag="ACIZE9_001456"
     CDS             40391..>40814
                     /locus_tag="ACIZE9_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HGC6093325.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
BASE COUNT        12670 a         7412 c         7662 g        13070 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctatcaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag
    10681 tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc
    10741 catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg
    10801 tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt
    10861 agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca
    10921 ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga
    10981 tacattttcg gaccgattaa ttttaaccat tctatttatt tgcttaccta ttagatatca
    11041 ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata
    11101 ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg
    11161 aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg
    11221 tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa
    11281 gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta
    11341 ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta
    11401 cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca
    11461 atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca
    11521 ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg
    11581 atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt
    11641 ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca
    11701 acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac
    11761 gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg
    11821 ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt
    11881 tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga
    11941 ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata
    12001 cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat
    12061 aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca
    12121 ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa acgaattcct
    12181 gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca
    12241 aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca
    12301 atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt
    12361 atttctccat tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt
    12421 cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat
    12481 cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa
    12541 atacattttc aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc
    12601 ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt
    12661 ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat
    12721 cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata
    12781 aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg
    12841 aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag
    12901 attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa
    12961 gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc
    13021 aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca
    13081 tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc
    13141 atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat
    13201 ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc
    13261 acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat tcagctagtt
    13321 ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca cgctgtactg
    13381 ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg gacatgaact
    13441 tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga taagcgctta
    13501 caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc tgctgtcagt
    13561 ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta tgtcagctac
    13621 ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct cttttatggt
    13681 cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa aacaaactgt
    13741 gatcatcgga ttagtgattg catcgatttg tggtatcctc cccctcttct cacaaagtta
    13801 cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga tcaattcttt
    13861 ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta tgattggttt
    13921 tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag gacagctagt
    13981 acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta ttcttgtctt
    14041 gtttgttttg tttgttccta cacctgaaac aactgaactt caatcgcatg gcacagcccc
    14101 aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt ttctcttgct
    14161 ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga cgacttattc
    14221 tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg caagtatggc
    14281 tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc ttacactttc
    14341 tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc tgtatgtgat
    14401 tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt acttattcaa
    14461 ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa tcttattggt
    14521 tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct cttttgcttc
    14581 tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt tgattagcgc
    14641 gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa gagtagatga
    14701 agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta aaatgacaaa
    14761 tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc gccatggact
    14821 gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact ggtacatgga
    14881 tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac cttccatgtt
    14941 taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac atccatgtgg
    15001 aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag gacatacatc
    15061 agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg gctggacagc
    15121 aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg atatcgcaaa
    15181 agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg aaacggagat
    15241 tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag aactaatatc
    15301 tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg tagaagctat
    15361 ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga aagctcgtaa
    15421 acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc aacttcaagt
    15481 ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt cttctttact
    15541 gaatcagatc tggtcagtat cagaagaagc cttcaagtta tgtagtgatt tgttttttat
    15601 cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat cattcatgat
    15661 caatcaatat cttttttttg acgaggaaat caataaacga acgatattag cattaagagg
    15721 acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct tgtggttgat
    15781 tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca tcgtctaccc
    15841 taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag ggtttattta
    15901 tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag aaggaacgct
    15961 tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt gcggagatat
    16021 cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc aagaaaaata
    16081 tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg gcgcttttat
    16141 cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt tcgctgtttt
    16201 attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct tattgaatga
    16261 cactatcaca cagattacta ctccatattt caaattctat gaacaagatg ctttatgcaa
    16321 actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag ggatgttatc
    16381 tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa atgaaaagta
    16441 cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag caagcccaat
    16501 ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt atgaagaatt
    16561 tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac ctatcaaaga
    16621 tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg atagaacagg
    16681 cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc cacttgtctt
    16741 aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat atcagaagac
    16801 tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc ttaattctgt
    16861 tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa tacgacaagt
    16921 aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc tagtttccca
    16981 agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc gattttaaga
    17041 tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct attgaaagca
    17101 gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc agaagcagct
    17161 ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa gcctatcata
    17221 gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa tacagcatta
    17281 ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg tacgagtttt
    17341 ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac cccttgaagg
    17401 acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat tacagcgttg
    17461 tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc aagtgcgaca
    17521 tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa gctgaaactt
    17581 ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt tccgatccat
    17641 ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt gtttccagtg
    17701 atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt tccttcgaag
    17761 accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac taaaatgact
    17821 gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa tttatatctt
    17881 gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa agcagtaggt
    17941 gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac tactccttga
    18001 gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact gattaaacca
    18061 gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg gatcacttct
    18121 gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac gaggatggag
    18181 ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag ttcctccctt
    18241 gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt cttcgctgtc
    18301 aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg tatctttcaa
    18361 agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa catccgtatg
    18421 acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt tgatgttcat
    18481 ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt tcatatcatt
    18541 cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt aataaatctt
    18601 gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga agatgtgcct
    18661 cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga ttatcaagca
    18721 gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg ccatcttctg
    18781 gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca tactgctcca
    18841 cgcgctcgat catagctttg atataacttt cttctatttt attttctgat aatagcggct
    18901 gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat tggatcattt
    18961 cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct aaaagtttgt
    19021 tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct tttaattcga
    19081 tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat cctggtatca
    19141 gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc atgattggat
    19201 gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta gaaaaaataa
    19261 tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc tctgtaaaaa
    19321 agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag ctaatgccac
    19381 ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc gcttttctga
    19441 tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg ctcttcccta
    19501 ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa gcatattgat
    19561 gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata cgaaaatagg
    19621 cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca aattctacgg
    19681 ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa aaatcaagtg
    19741 caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa aatataatct
    19801 ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta atgtcagtga
    19861 ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt tttccaattc
    19921 gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt gcgaatcgaa
    19981 gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa taatcaatgg
    20041 aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc atcaaacgag
    20101 cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc ctaaaaccag
    20161 ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt atctttttga
    20221 tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga aaaacagaaa
    20281 cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct tgttcggtat
    20341 acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt gctcggaatt
    20401 tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat tgtttgatcg
    20461 cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt tctcttggtg
    20521 ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac ttatattcta
    20581 gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg atttttttta
    20641 cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg accaaatgtc
    20701 tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt ttttgaggtc
    20761 agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt ttcaaagtga
    20821 ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa agctgtttct
    20881 ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc ttctgtttca
    20941 ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat tgaacctctt
    21001 aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag tagttctata
    21061 ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat tcttacaaat
    21121 atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca aaattttcat
    21181 ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta atgtctcgta
    21241 aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt cttcatgata
    21301 actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat cgataccaaa
    21361 gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat cttttgtttg
    21421 tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt tgatgcggaa
    21481 ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat cgaagtaatc
    21541 attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat ctggttcgcc
    21601 gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat agctgttcgc
    21661 agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat aatgcatttc
    21721 tacttctaaa atatccccta attttccgct ttcgattact ttttggactg tcaagaagtc
    21781 agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt ttgctaatgc
    21841 aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta gtacattctt
    21901 accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg tagtgatgac
    21961 aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat attcgatgtc
    22021 ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat tgattttgtt
    22081 cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat tgccaagata
    22141 agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata tcctagaaaa
    22201 gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac acttgttatc
    22261 attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga tagtagcgga
    22321 accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt gaagaaaaac
    22381 taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac atccgtagga
    22441 atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg tatacttccc
    22501 attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa gaattccgtt
    22561 tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg attgatccta
    22621 attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg gcggatttat
    22681 cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta gatcaaatcg
    22741 gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat tctcaaatca
    22801 cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc atggctgaag
    22861 aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc gccattttta
    22921 ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg aagcatgtag
    22981 aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa caggctgata
    23041 tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact ttctcctctc
    23101 aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct caaaattttg
    23161 aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc cttcttaaag
    23221 aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag tgtttgatag
    23281 gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac ctcagcctgt
    23341 ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct aacttctgtt
    23401 tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca gtatacatgc
    23461 agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta cttctttttg
    23521 aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat gactgttgac
    23581 catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga ttctcagatc
    23641 ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga gtgtccgtcc
    23701 attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg tgaacaactt
    23761 tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc cccccgtagg
    23821 ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat tcgtttcatc
    23881 aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg tatgtttctc
    23941 aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat ctgcacctgg
    24001 atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt ggattttagc
    24061 catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga tctgctgatc
    24121 cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta ttcctgagag
    24181 aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca tttgtgttct
    24241 ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc cgctgctcct
    24301 ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca aagtacagtc
    24361 cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc ttaccgcctg
    24421 ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc aactgtcctg
    24481 ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat ggaacatatt
    24541 tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct gtcacatcga
    24601 ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat acccagctga
    24661 cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct tgatcacgaa
    24721 cgacgaattc tgctccagca agtgtttggt ctgatgtaac gtcaccatct actttaacaa
    24781 atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt gtatgcccgt
    24841 tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg ttcaaatgca
    24901 tatagtaaac gaatttcaat gtaccgccag gagttaatga aggaatataa ttcggatcaa
    24961 ctgaaaccgt gaatccgtct gtttgctcag tgacagaata atttactggg tcgatttctt
    25021 tatttccatc atataaggca taagcatacg ttcctgaaga atcattatca aatgttaaag
    25081 cagcgtcatg agtatcgata agtttgaatg ttgtgtactt gttttgcgtt ccttctttat
    25141 cagcgatacc taatgggata ttgacagaaa tctcatattg aattttttca ccgattgcga
    25201 catcttttcc attcaattga ggtgttgttt tatcaacttt agacgtatca tttttgatgg
    25261 tcttttctac tggtgtttgg ctatttgcca ggatctcaaa aggcgtgatt gtttgctttt
    25321 caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt ccaacttcta
    25381 aatgattaac gatcaactgg cctttttcaa tagatgcctc ggcaaagtca ttgttgccga
    25441 tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatcagtt gtccaagtgt
    25501 acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtgttcct tcttctttag
    25561 aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt tttgtaactt
    25621 tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta tctagttctt
    25681 ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca gggaaagcta
    25741 aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc gtgtagactg
    25801 catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca gcatctgtcg
    25861 ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt gctgcatcca
    25921 cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa actgaaaatg
    25981 aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg ctgttttgga
    26041 ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga gctgctgtct
    26101 cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa ataaggaaaa
    26161 ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc ctgttctttt
    26221 tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc ctaaaagtgt
    26281 atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt tattgactac
    26341 tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg taaacggaat
    26401 ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc gataacttcc
    26461 tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt gaagcgcatc
    26521 tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat ttcctgcttt
    26581 gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg tctcgatttt
    26641 gacaaattgc ttactccctg tatatacaga gactttcttt gtactgacac caaaaccaaa
    26701 atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc ttagctgcat
    26761 ctgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga tcgaaaataa
    26821 aacatcaaat ccgtgaggtt tcttgtgtat gacaaagcct tctgtcagct tttctccatt
    26881 cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac tatctgacaa
    26941 ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg aataagtgat
    27001 tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa aaggtggatc
    27061 agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt tttgattgtt
    27121 ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga cgacttctgg
    27181 tactttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt tagcggccag
    27241 agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt ctgcggtaaa
    27301 cataccggaa gacgcaccgt tttttgcgat ctctgcttgt gcttcttcta ccgttttgcc
    27361 cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg tgacaccatt
    27421 taatcctcga tacgtttgta ataaagcttt ttcttgtccg tcatttggat gatttttcgg
    27481 cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt ctgtttctgt
    27541 ttctgttgct acctgagtaa aagctggttt aaatagtaac aagaagagac acatactaag
    27601 ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa aagataccaa
    27661 atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc aattcctccc
    27721 gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg gttgtttttg
    27781 gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga cccatcttcg
    27841 tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt aaaagtttcg
    27901 gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt ttcttgtcca
    27961 tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc tccttttaat
    28021 gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag tcgattttga
    28081 tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta aatgattttt
    28141 ccatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc ggcaggacca
    28201 gctgtttcaa cgactcgata tttaccaggt gtgagtgaat caaaactggc aagacctttt
    28261 tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt tttctgtagg
    28321 gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc atacttacgt
    28381 actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt atcatcggaa
    28441 gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt gatttcccaa
    28501 gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag cgtataggtc
    28561 atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc atgatctgtt
    28621 agtaaagtat caatagaatc tcctgttaat ttgaaaacag cgccaataag atccttttca
    28681 cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt agtatttttc
    28741 catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc tttgattgtt
    28801 tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat ctcttgataa
    28861 ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacgt atttgttgta
    28921 tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc atttgtcgta
    28981 tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt gttgtcaaat
    29041 tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga tggtataccg
    29101 aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc gttcatttga
    29161 taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg gtaatggatt
    29221 tggatttctt ggtcttttcc taaatagatc tgattgctct tgatggtatt tccttctatg
    29281 gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga aagtgtacca
    29341 ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct tacagttgct
    29401 gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg atcagctgat
    29461 tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg agactctact
    29521 tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag accatgtatt
    29581 tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa cgtactgtcg
    29641 attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat tagagaagta
    29701 tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct gcttgattgt
    29761 gcgtgtaccc gctgtacttt ataggaaaat gttggtacac catccgtcag caaaacgatc
    29821 acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag tgctttttgt
    29881 gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt tttcactgaa
    29941 tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct tgagtagccg
    30001 acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc gacaaaacga
    30061 tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc tgaccagtct
    30121 acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg agcattcaaa
    30181 taaacatcaa acaatccggg tgtacttgtt tcctttgcat actttcgtat cgcatagtct
    30241 gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt aggatctcca
    30301 ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg atgatcaaga
    30361 acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg atcatctgtt
    30421 gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa ggataatgta
    30481 ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc ttctatttcg
    30541 tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc aataatgtca
    30601 tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc tggatcgatt
    30661 ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt aattttcccg
    30721 ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact taagtaattt
    30781 tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc atttagcttg
    30841 atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat tgtttctaaa
    30901 actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt tgataaactc
    30961 aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat ttttcccctc
    31021 ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa acaggcgtta
    31081 cataatttta tttattttaa tatgataatt attatacgaa gggcgctaaa gggaatcaca
    31141 ccaattttca taccaattgg tttcatttat gaagttgatt ccttcgatta atgagcgttt
    31201 cattgaaaga aaagggttga gggagaaaaa catatgatca ggttgttgga aggaaactat
    31261 agaaagatgg aaaaaatcat tcgaattctg tccatttctg acaagtggat gactaaaaaa
    31321 gaacttgcca aacgaattgg tagttcagaa tctacatttg taaggtatat cgaagagatc
    31381 aaaatccgct ggggaacgga tgtaacgatt caatcttcac aaaaattggg gtatcgtctt
    31441 gaacatttga atgtaccagc ttatttaaat gttctgatgg aaatgtcgca aagttctaca
    31501 aacagtcgtt tattaaatga gattattgtc aatccgggta aaacgattga gtattattgt
    31561 gaaaaaattt ccatcagccg gtcttctttt acacgtaagt tgaaacaatg caatcaaatt
    31621 ttagaaagct atttattaaa agtgatcgtt gaccaaggtt ttcagttaac tagccttaaa
    31681 agtgagctcc agttgcgtat ctttgttacc tttttctttt taagttacta cggaagacgc
    31741 acgttgccat ttccaatcga aaaaaagaag atcaaagaaa ttatggtcaa gaataattgt
    31801 cagatgaatt tgtttcagga agaaagccca tatgagcaat ctttctttat tatgtatttt
    31861 gttgtgcatc tcatgagaga atcccaagga actccatttg aatggaaagc tggagactct
    31921 tatgtacagt tgataaatat cgataaaaaa gacttcttaa tcttgaaaaa tctcttagga
    31981 aaattgaagt acagcagcta tataaaagta gtgaactatt ttgtcaatac gattttttca
    32041 gaattttcgg agaaagaaaa aaatgaaatc agtgagcaga tacgaaaaaa tatgtcctac
    32101 tgttcgtttt catccgctga ttgcaaagaa aaaaacgaag aatatgttgt tcaattatta
    32161 acgcaaattt attttttctc ccgtattttc ccatacgata cgactcattt gacgatccgt
    32221 gcaacttact ttgcacagca gatgcaacac cgccagatac gtctatatgc tggatttcgt
    32281 gcagaacttc aattttattc cactctactg aatcagaatc tgatttatta tttatctagc
    32341 tatatctttt ggatgcttat cggtaatcct gaaattcacc attatacttc tgataaaaaa
    32401 atactgatta tcagcgactt aagtcttcga catagtcaat atattgaaga atatatcagt
    32461 gatattcttg ctgtgcataa aattcactct gagacaactg ctattactga agatcagctg
    32521 tcgaaataca atcttctcga gtatgatctg atcgttacga atcaacccat tttgaatgcc
    32581 catgttcctc atatattgat tgatgatagt gtgtcattcg caaatgaaga agaactcatc
    32641 cgcttattcg agttatgaat aatcaaaaaa cagctatgta taaaccaccc tgataaaaat
    32701 ttcaggacaa atacacatag ctgtttcttt ttattgtatt ccttcagcaa tccaacgaga
    32761 tttatagcga aagtctttta acaactcttc ttttgtccaa ttatttgcaa tgagatccgt
    32821 caaagtgttc attacgaggg tcatggaaaa gtataggaaa ctaactgctt cttccgacga
    32881 ttgaatggag aaatgattga ttcttaataa ttccagccat ttttcgttca ttggagaatc
    32941 agccgatagt tctctacgtt tggttgtctg ctgatcattt cgctgggtta acaagtataa
    33001 cctttgccaa tagatacttt cgtgatctaa gtcgcagcac cactctaaat atttttcgat
    33061 ccccaaaaag aaatgttgtt tgttttcgct aatgaatttt aagatatctt gatggactat
    33121 gtgagaactg cttttgatcg tatacaaata agcatcttcc aaatcttgaa aatatttata
    33181 aaaagcaccg cgcgacatcc ccatcttgtc aacgatttct gagactttga cttggctgat
    33241 gtgctgtgag caaaatatct ccagtaatag gtcatcgatt ctctgtttct ttgcgttcga
    33301 taaattgaaa aaagtttctt ttggcatcca catctctcct ttatctctga ttatacgtgg
    33361 atagcccttc attgtcatga aggattcatt ccttcttttt ctcttcttct gtcaagtacc
    33421 catcttccat tcgataaacg cgatcactcc attgaatcat acggacatca tgagtaacca
    33481 taatagtcgc tttttgtttc tcatgagctt ctttaactag taatttgacg acttcatatg
    33541 catgatctgt atccaaacta gctgttggtt cgtctgctaa gatcaagctt ggctcattat
    33601 ataaagcgcg agcaattgcc actctctgtc tttctccacc agaaaggtct ttaggataac
    33661 tatttttaag tgactggata tctaaagatt gcagcaagga atcgattttt gttgaatctt
    33721 ctttttttga agtaacttgg tcaactagtt caaattgttc ctttaccgtt aaaaaaggaa
    33781 tcaaattaga gctttggaga ataaatccta tttctttaaa gcgtaaatct gctcgttttt
    33841 tttctggaag ctcagttagt gagtgaccgt tgatcactat ttctccggaa gtcggtgttt
    33901 gcaatcctcc tgaaatggta aggaaagtac ttttacctga accagaagga ccaatgatgc
    33961 tgacgaattc tccttccttt acataaaaat caattgcttt caaagctgag acctttgtat
    34021 gaccagaacc aaatgttttg gtaacttttt tcatcgttaa tatttttttc atttttatta
    34081 acctcctatt gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa acaatccgcc
    34141 tagcattgcg acaatgatca aaatcccact atatagcaac cattgtgacc aaaaaacagc
    34201 aaaaggcatc gcgcttggta aaatcagact agtcaaataa gcaaacaaaa gagcaagcag
    34261 aacgcctacc accccaacaa taaaggactg tgctactaaa gatttagcga tgaagaaatt
    34321 tttgatccct tgtgctttca ttactccaaa aatagcagtc ttctgaagtg tcatcacgta
    34381 catgaaaata ccgaccacgg cagcaaccac taagaacaaa aagtatatca tcgcatttaa
    34441 ggtcatattt tgggcagaat agccaggaat actttcaatg aatgtcccaa tagttaataa
    34501 ctgtagaccc ttcgatgctt tttctttcga aattttagct gaatccttta ttacgatccc
    34561 attgatcggc tgttcttctt cagaagcaaa cggctgttgt ccatacttca aagcagtcca
    34621 cgtatctagg gacgcataga tgacgggaga aactgtgtaa taagtttcag gaaagatacc
    34681 gacaatcgtc aaaggatcgt cgtaactgcc aattttgatc gtatctccaa ttttatagcc
    34741 tgaatcagcc agattttgag agatgatgat ttcattcttt gttttaaatt catgcccttt
    34801 cgtgagtttt ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa cattttcttt
    34861 gttttttcct ttgattgctc cgctgtacaa tccgattggt gctttctctc ctccttcaat
    34921 gtatttcaga tctcctcttg ttaattgtga agctgcaaat acttgatttg catcctccga
    34981 caaaacaatc tcttgtgcgt cccaatcatc gattgctttt ttaaactctt ctgaaagtcc
    35041 attcgctagt cctgacaaca tgaatacgac atacgcaatc aagaacataa taccgacgat
    35101 caagccatat cgtaatttag aatagcgaat ttctttgata gctagaaaca tttgtttttc
    35161 ctccctatga tagattgata gtgacaaaat gtcacttgtt gaatagtgta actctaaagt
    35221 gacaatttgt cacttgtgtt gtttttttct tatcaataaa ttgtctaaga catctttcga
    35281 taaaacctta acatgagtca taaaaaattt atttaagcct tatttatgct ttccatgata
    35341 aactaaagtg accaaatcaa tgaggtggga aaatgattaa actattagta gtagaagacg
    35401 ataaagtatt atccaataat ataaaagaaa tactcgctgc aatcggcgag ataacacaag
    35461 tttatgatgg tagtgaagga ctgttcgagt tggaaagtgg agtttatgat cttgcaatct
    35521 tggatttgat gatgccggaa atgaatggat atgaagtgtt agcaaaaata cggaaagaaa
    35581 aaatacagac tccagtattg attttgactg caaaagatag tttggaagat aagattgaag
    35641 gatttgaacg aggtgcagat gattatctaa caaaaccttt ctatcgagaa gaactgatca
    35701 tgcgcgtgaa agcattattg aaacgctcgc taggtctctt tgatgaaaat gttctgaagt
    35761 ataaggatat cagttgtgat ttaaaaagca atgaagtctt gtataaagaa caagttttgc
    35821 ccatacaagg aaaagagttt gaattgctcg tttatttttt acaaaataag ggaatcattt
    35881 tgacaaaaga gcagatattt gaccggatct ggggatttga ttctgatacg acgattacag
    35941 ttattgaagt ttatatgagc aacttacgaa aacatctgcg aagtactgga ttggataaag
    36001 aaatcaaaac cttacgtaat gtcggttata tactgcaaag ggtgtgatgc aatgaatgga
    36061 gatattacac gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc atttgctttt
    36121 atcttttttc ttttgggatt cattacttta cagatattaa accaatctgc atacagagaa
    36181 acagatctgt cattagagaa aataaatttt gattctcgaa cagtacaatt agagatacaa
    36241 agatatcagc aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa cagaacaaac
    36301 atggaacagc cattaatgga accatcaaat gaccgtttta acactcaagt gatcttgtgg
    36361 tctaaaaatg gtgagatatt gaataaagca gctattggtg ggcgtttcaa ccaaatcaaa
    36421 gaattaaaaa tggatacgaa aaatctgaat accatccaaa atattgaatt aaatgaagac
    36481 agtggctcat ctgccctctc tttccgttcg attacgaaaa aagcggagac gaatcaagat
    36541 ggcgttgcct acatccaaat tttagaaaat acaaatcaaa tcaagaattc attagcgact
    36601 tttcgcacga ttatgatttt gtgtatgatt gttttttgga ttctctctat tggtatcagt
    36661 tattacttgt ctagtctaag catgcgccct attattcttt cttggagaag acaaaaagaa
    36721 tttgttgaga atgcttctca tgaattgcgc acaccgttaa cgattattca aaatagtttg
    36781 gaacatcttt ttaccaagcc taatcatact attattgaag aatccgaaag catcgctcaa
    36841 gcattgtcag agacgaggcg cctcactgga ttgacttcgg atttgctgac aatcgctcgg
    36901 aatgattctg atcagcagct gctttcaaag caaatgatca atacacaaga atatatcgaa
    36961 caacttgtta aaccatttca agagatggcc atcatagatg gaaaagagtt tattctccat
    37021 aacgatgcaa cattagaagt accaattgat gaaaaaaaaa tccatcaagt tttggttatt
    37081 ttgctggata atgcattaaa atatacgaat ccagaagata agatcatttt ggattcatct
    37141 gttaaccata aagaatggct gattcacgta aagaatactg gcccttctat cagtgaagaa
    37201 gatcaagcaa ggatttttga tcgattttat cgggaagatc aatctcgggc gaaagagact
    37261 ggcggatacg ggcttggctt ggcaattgca aaacaggtaa tcgaacagca tcatggacag
    37321 atttctgtat ccaattatct tccacaagga gtcgatttta aagtccaatt gccgttgaag
    37381 cctaaaaaat aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt cacagccctt
    37441 ttttgttgcg aataaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttct
    37501 ttaagctgac cacttctgtc acaacctctt tagcttacgc ttacgatttt ttattgcggt
    37561 cttcaatgtg tacatcaccg cttgtgtcaa tatccaattc ttctcggcta acatcttctg
    37621 tcactttttc aacatcttca tgttcttctt tatgaatccc aacttcttca cgaataactg
    37681 tatgtttgct tacatctact tgctcttctt tgattgggat agtaatcgtg tcatcttcca
    37741 atttttcgtc tgttccctgt gaagattgat ctgttactgg tttgcgttcg atgacgattt
    37801 cttcacgttt gaccggtact tctaccgttt cagtatcgtt gaccacatgt ttgtggatgt
    37861 cgacttctcc agttgtcaca tcatgtgtat ttacatctaa tttttcttct tttagttgaa
    37921 ttgtatcatc atctagattt ggtttgcgat cgatgtcttc agtcttgctt gtacccattg
    37981 tatcagtctc gccaggtacg tccatcggat cagttcctgg tgtcatattc aatggatccg
    38041 ttgtattttg aaagcctgtc gtgccaccta cgtccattgg atctgttcca gtgccagttt
    38101 ctaatccagt ccccattgtg cttgctgggc taacagtatc ttgtgtatcc attgtatctt
    38161 ctgttgtttc tggctgacga tagcctttta ctgtgatgac aaattttcca tcagaaatat
    38221 ctcctctata ttgatataaa ggatcatttt ctggtgtagc cgtctcagaa tcataggtat
    38281 caaaagaaaa agtatctttt attttttccc ataaagaacg gtcttcttca ccatccatcc
    38341 gattttcatc tgtttcaaca tctataccag acaatccgtc aaatcctagt ctagatgctg
    38401 cttcatcagt agtataaata acgatatcat ctcgttcata cccttcgtta cgcaaccgtt
    38461 caattactga taatgcttct tccctcgtac tatagcttcc gatgaccgtt aaatttttct
    38521 cttccatgta aattcctcct agcaaataga tttatgattg gtatattgtt acttataaat
    38581 ttattctata ggagacgatt gttttctaca aatatttaga ttggaatttg attaaaacaa
    38641 tttaattgaa atttgaaaac atttatgtta atgaaagtca tattctaata aaatgtcatt
    38701 tgtttctata tgaattttta tgaaaaattt catataattt ccactcgttg tgatggttta
    38761 atttatccaa tccatcaata agcaaacaac ttatataaaa aaggattaat tctcaatata
    38821 attgctccta ccatagaata aatcttcatg taaagtaatg aagtaccaac tatttctaat
    38881 acttctttaa gaattatccc aacaatatcg ttagacaaac cattattgaa taaatggaga
    38941 gccaatcgat tctgaaaaaa tgttttctaa tttttcggaa ataaaagaaa gagcctcctg
    39001 ccattagaac gaaccaaatc catttcattg ctcatgaagt aaccacatag ctaaaaagag
    39061 gataaatcaa ttaaaagatc aaaagaatga ctgcactaat aaaataacta aaaatgtatc
    39121 ttcttacttc atatctttta gctagtactt agttaaaaat ttgcttccta agatcaagac
    39181 aaactgtcta tcttcatttg atgaaatgcg gtaaaatata gaaaatgaac actattggag
    39241 ggaatttgta atggacagca aaactagaaa acaactgcaa gaaaagttaa agcaacgtac
    39301 acacttgctc ccttccgtct ttcaacagtt tttagaagaa aatcgttctt ccctttcatt
    39361 aggcagtcgc tatgaatacg caaaagattt tcatctgttt actgattatt tgagaaaagt
    39421 attttctgaa gaagtggatg atcagctgat tatccattta gaaaaacaag attatcagaa
    39481 tttcttagct aaaatctatc gacatactcg ttcgttccaa actacagcga accaagaaac
    39541 ggagcaattg tttgaaaata gctattacgg gatttcaagg aagcaatatt cattaaatca
    39601 ttttttacga tttttgtatc aaaaaggact gattgaagaa gagatttctc ttttgggtac
    39661 aagtttaccg gaaacaacca aagcagctcc gcgatatatc gatgcagaac ttttcaaaga
    39721 ttttgagcat ttgtttatcc cgattgaagg ctttcaaaca agcagagaag ctagctttga
    39781 agaaaagaat agaccgagga accttgcaat tactgccatt cttctgtatt gcggattaaa
    39841 gatccatgaa gtagtagaac ttaaacgtaa agatgtatct ttgaccaagc agattcttaa
    39901 tctgaataga aaagaaaaca gactgaataa agtaccaata ccaaaagaag cgatgccatt
    39961 tctggagaac tattttaagt taacagcaca aaatacggac gaaaattctt ttgtttttcg
    40021 ttcctcacat gatcagcaaa tttctcctcg gactattcgc caaattttga gcaaaattac
    40081 agtatataaa aacgtatcgc cagaactatg cagaaaaaca tatcgttatt atgcagaact
    40141 atatttagat gatgctgacg cggtaaatta tttatgtggt aatcgatacc tctcatccca
    40201 ttcttttcaa gatatctggg aaaagatggt tgatttttct tatcacgaat tagcggcatt
    40261 cgttcgggtt tcttccatat aaaacaaatg tatgatcttt ttttcacaat aaactatgtt
    40321 attatataaa ggattatgtt acgattatct tgaatttgta tattacttaa caaaagataa
    40381 tggagtgtga atgatggaga ccataacgta ttcccctttg aacttattta cgaattttca
    40441 agaagctgca gctaactttt ccgagacccc gattatcttt gatgagccac tttcagcttt
    40501 cccagaatta ggacttgaaa caacttacaa aaaatgctgc gaaagtgtgt tgaaacgggc
    40561 ttatcaattg gctcatcttg gagtgaaatc cggagacaaa gttattattt ataagagttc
    40621 cgcttttgac acataccttc tagctgtttc tgtgtcttac cttggtgcag tgcctgtcat
    40681 gacttcttat catctaccaa caacaacaat ggaagtattt atcgatcgtt tagaagaccc
    40741 tttcatttta tttgatgatg agacaaaaaa gcgagtgaga gaaatttcaa atggaacaaa
    40801 atcaaaacag attc
//
LOCUS       DBBGSP010000024        37143 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000024 DBBGSP010000000
VERSION     DBBGSP010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37143
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.024"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            2..74
                     /locus_tag="ACIZE9_001457"
     tRNA            2..74
                     /locus_tag="ACIZE9_001457"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="ACIZE9_001458"
     tRNA            78..150
                     /locus_tag="ACIZE9_001458"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="ACIZE9_001459"
     tRNA            155..225
                     /locus_tag="ACIZE9_001459"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="ACIZE9_001460"
     tRNA            238..311
                     /locus_tag="ACIZE9_001460"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="ACIZE9_001461"
     tRNA            323..394
                     /locus_tag="ACIZE9_001461"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /gene="metK"
                     /locus_tag="ACIZE9_001462"
     CDS             660..1853
                     /gene="metK"
                     /locus_tag="ACIZE9_001462"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGC6093326.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="ACIZE9_001463"
     CDS             1983..3455
                     /locus_tag="ACIZE9_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HGC6093327.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="ACIZE9_001464"
     CDS             3538..4326
                     /locus_tag="ACIZE9_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6093328.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="ACIZE9_001465"
     CDS             complement(4393..5061)
                     /locus_tag="ACIZE9_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HGC6093329.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="ACIZE9_001466"
     CDS             5176..6888
                     /locus_tag="ACIZE9_001466"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093330.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="ACIZE9_001467"
     CDS             6891..8663
                     /locus_tag="ACIZE9_001467"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093331.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(8745..9866)
                     /locus_tag="ACIZE9_001468"
     CDS             complement(8745..9866)
                     /locus_tag="ACIZE9_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6093332.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(9938..11218)
                     /locus_tag="ACIZE9_001469"
     CDS             complement(9938..11218)
                     /locus_tag="ACIZE9_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HGC6093333.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEETLSDLNKQITMLKNDINLLKKEKEDLNDEINQKYDETLKNVYSSLIVSN
                     IEETSSSEIKNKLSLLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            complement(11309..11761)
                     /locus_tag="ACIZE9_001470"
     CDS             complement(11309..11761)
                     /locus_tag="ACIZE9_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGC6093334.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(11774..12184)
                     /locus_tag="ACIZE9_001471"
     CDS             complement(11774..12184)
                     /locus_tag="ACIZE9_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6093335.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            12459..12671
                     /locus_tag="ACIZE9_001472"
     CDS             12459..12671
                     /locus_tag="ACIZE9_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiprotein-bridging factor 1 family protein"
                     /protein_id="HGC6093336.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            12674..12886
                     /locus_tag="ACIZE9_001473"
     CDS             12674..12886
                     /locus_tag="ACIZE9_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093337.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            13026..13181
                     /locus_tag="ACIZE9_001474"
     CDS             13026..13181
                     /locus_tag="ACIZE9_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093338.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(13178..13402)
                     /locus_tag="ACIZE9_001475"
     CDS             complement(13178..13402)
                     /locus_tag="ACIZE9_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HGC6093339.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            13480..13668
                     /locus_tag="ACIZE9_001476"
     CDS             13480..13668
                     /locus_tag="ACIZE9_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093340.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            13665..13838
                     /locus_tag="ACIZE9_001477"
     CDS             13665..13838
                     /locus_tag="ACIZE9_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093341.1"
                     /translation="MKKTDTLFIGFILGLLVIVAHQSIIGGSLFAALMVLINLLDSKE
                     RSNYGTRRSAKNR"
     gene            13807..13935
                     /locus_tag="ACIZE9_001478"
     CDS             13807..13935
                     /locus_tag="ACIZE9_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093342.1"
                     /translation="MAREEALKIGKVIADNRWGNSRPIILSKQHIEKQKAWQQIKK"
     gene            13994..14329
                     /locus_tag="ACIZE9_001479"
     CDS             13994..14329
                     /locus_tag="ACIZE9_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093343.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            14562..15503
                     /locus_tag="ACIZE9_001480"
     CDS             14562..15503
                     /locus_tag="ACIZE9_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lambda-exonuclease family protein"
                     /protein_id="HGC6093344.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            15505..16395
                     /locus_tag="ACIZE9_001481"
     CDS             15505..16395
                     /locus_tag="ACIZE9_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HGC6093345.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            16438..17238
                     /locus_tag="ACIZE9_001482"
     CDS             16438..17238
                     /locus_tag="ACIZE9_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HGC6093346.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            17253..18104
                     /locus_tag="ACIZE9_001483"
     CDS             17253..18104
                     /locus_tag="ACIZE9_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6093347.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            18305..18766
                     /locus_tag="ACIZE9_001484"
     CDS             18305..18766
                     /locus_tag="ACIZE9_001484"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6093348.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            18792..19244
                     /locus_tag="ACIZE9_001485"
     CDS             18792..19244
                     /locus_tag="ACIZE9_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093349.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            19350..19544
                     /locus_tag="ACIZE9_001486"
     CDS             19350..19544
                     /locus_tag="ACIZE9_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093350.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNGFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            19575..19961
                     /locus_tag="ACIZE9_001487"
     CDS             19575..19961
                     /locus_tag="ACIZE9_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093351.1"
                     /translation="MKKLHQLISEKESELQNLEDSLGLGFPIVEQAKMTQISHLRLEL
                     EDLRQIEKSIQLNDNQKIVLEWLKSETILTREAPILSVNAFSDKNLLGKLPDKVRKAY
                     KLLACKQEYEVLSAFAQWGLEQEEAE"
     gene            19958..20161
                     /locus_tag="ACIZE9_001488"
     CDS             19958..20161
                     /locus_tag="ACIZE9_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HGC6093352.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASNAIRKFGISILNDDRKWEEMR"
     gene            20158..20454
                     /locus_tag="ACIZE9_001489"
     CDS             20158..20454
                     /locus_tag="ACIZE9_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093353.1"
                     /translation="MKIKDGFYASSHGIGGLMLDMPIKNPKTRQKSKFKIGDMVRCKA
                     EEFIYPFRGYVEHVYNHSAIIHIENTMECDKWLAKSKDNLAVARLVDMELINDK"
     gene            20530..20946
                     /locus_tag="ACIZE9_001490"
     CDS             20530..20946
                     /locus_tag="ACIZE9_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HGC6093354.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            21207..21344
                     /locus_tag="ACIZE9_001491"
     CDS             21207..21344
                     /locus_tag="ACIZE9_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093355.1"
                     /translation="MDKEIKVTVKLDLTELKELLNKASDQVEQLQETLDEIANFKIQV
                     S"
     gene            21754..21984
                     /locus_tag="ACIZE9_001492"
     CDS             21754..21984
                     /locus_tag="ACIZE9_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093356.1"
                     /translation="MRNYWYISLTNEYPRTIDDCSVRVVRSVQIKKKYSIVEMTREAT
                     PKEIDKCKLLYCGHGFYDEPNIQNNINKNLRD"
     gene            22143..22976
                     /gene="terS"
                     /locus_tag="ACIZE9_001493"
     CDS             22143..22976
                     /gene="terS"
                     /locus_tag="ACIZE9_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit"
                     /protein_id="HGC6093357.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELKSNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPKRNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            22969..24384
                     /locus_tag="ACIZE9_001494"
     CDS             22969..24384
                     /locus_tag="ACIZE9_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HGC6093358.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPENMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTTVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            24396..25925
                     /locus_tag="ACIZE9_001495"
     CDS             24396..25925
                     /locus_tag="ACIZE9_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGC6093359.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEYMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKDPTAKAEYVTKKLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            25843..26895
                     /locus_tag="ACIZE9_001496"
     CDS             25843..26895
                     /locus_tag="ACIZE9_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HGC6093360.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            26897..27214
                     /locus_tag="ACIZE9_001497"
     CDS             26897..27214
                     /locus_tag="ACIZE9_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093361.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            27341..27964
                     /locus_tag="ACIZE9_001498"
     CDS             27341..27964
                     /locus_tag="ACIZE9_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HGC6093362.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            27979..28869
                     /locus_tag="ACIZE9_001499"
     CDS             27979..28869
                     /locus_tag="ACIZE9_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 family protein"
                     /protein_id="HGC6093363.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            28892..29107
                     /locus_tag="ACIZE9_001500"
     CDS             28892..29107
                     /locus_tag="ACIZE9_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093364.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            29119..29460
                     /locus_tag="ACIZE9_001501"
     CDS             29119..29460
                     /locus_tag="ACIZE9_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093365.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            29460..29831
                     /locus_tag="ACIZE9_001502"
     CDS             29460..29831
                     /locus_tag="ACIZE9_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093366.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            29824..30219
                     /locus_tag="ACIZE9_001503"
     CDS             29824..30219
                     /locus_tag="ACIZE9_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HGC6093367.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            30221..30598
                     /locus_tag="ACIZE9_001504"
     CDS             30221..30598
                     /locus_tag="ACIZE9_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HGC6093368.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            30599..31207
                     /locus_tag="ACIZE9_001505"
     CDS             30599..31207
                     /locus_tag="ACIZE9_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HGC6093369.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            31207..31548
                     /locus_tag="ACIZE9_001506"
     CDS             31207..31548
                     /locus_tag="ACIZE9_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093370.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGPVVEEAAEVMEG
                     MQNAVDGKSVSEALSRAYSFIADILFEGQFTGEDYRQGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            31790..34579
                     /locus_tag="ACIZE9_001507"
     CDS             31790..34579
                     /locus_tag="ACIZE9_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HGC6093371.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            34569..35309
                     /locus_tag="ACIZE9_001508"
     CDS             34569..35309
                     /locus_tag="ACIZE9_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGC6093372.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            35306..>37143
                     /locus_tag="ACIZE9_001509"
     CDS             35306..>37143
                     /locus_tag="ACIZE9_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HGC6093373.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT        12787 a         5537 c         7545 g        11274 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattatttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaactgt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcacgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacctcgtt ataacggggt tctttttata
     8701 tattttatgt tgtttgtttt tataaggggc agaaaagggg caatttaaat ttctattttt
     8761 cctagttttt ctactagttg attttgcata tttttagttg tatgagtata aatctttaat
     8821 gttgtttttg aatcttcatg tcctacacga tccataatgg cttttaatgg gattcctaat
     8881 tctgtaagta gagaaatgtg ggaatgcctt aacatgtgag aagaaacttt tttatctagg
     8941 tttaattctt tggatactgc tcttaaagat tgattatatg cttgaataga tatcgggtta
     9001 ccatttttag agatgaaaat gtatttatct ttattattct taattaattt gttttcttca
     9061 attaattgat ctatgatttc tttagcatta cttgataatt caatggttct ataagaacct
     9121 gtatttttag ttgttgtttt aatttttaac tcgtaatcat aagtaccaga aaccgtaatt
     9181 ttattaccat cataatcaga ttcagtcaaa gatatcaatt caccataacg tagtccagtt
     9241 aaaaacaaaa atttagtaat taaagaataa cgtgactgtt gatgtgaact tttttgttta
     9301 ctagcaatca tttgaacttc ttcttttgat aaataaccat ctttttcttt ttttatttct
     9361 tcgtttgtct taggttttct tgctaaagaa accccattta cgggattata ttttaatcca
     9421 tatcgacggt tggcgaattt aaaaatcatt cctgtaaaag tttttaaatg tattacataa
     9481 ttatatgata aatttttttc aaaatagtag taatctagca tatcttgtat aagattacta
     9541 ttaacgtttt ttacaagtac atcatctttt atatattttg aaattaatga tagataaacc
     9601 tgagttgttc gataggaact ttcttttaca gttggcttgt atttttcatc ccatttagtt
     9661 tttaattctc caaaagttag tggtaattct tcatttcgtt ttattttttc tgcgattttt
     9721 tcattcaaaa gtaagttagc ttgattccaa gcttggcgtg aattgctaga taaagtaacg
     9781 gacacttttc tctttttttc agttaaggga tccgtataac gttcggtgta cttaaatttt
     9841 ttgtcattta ttttttctaa ccacattatt tctattcctt tcgaatatac gttcctatta
     9901 attgttaaaa gaaaaagccc gaaggctttt tatatattta atcttttgac aattctaaag
     9961 atcgtctata ttgttcagct ttagctaatt ttgtaaatgt tactgttcca ttataatttt
    10021 ctaaaacaac tttctctatt tcgtctagtg aaactttgaa aaattctttt ctttgattaa
    10081 ttttattaac ttcttgtttt ctaaaatgat tatgcaattt agtttccaaa gacggagcgt
    10141 cctctgaaaa aatcatcgca tgaacgtcaa attcaaatgg aaccgatgca ctactcaatt
    10201 cttttattct atccataggt tctaatcttc tagtcatacc aattttatat atgtcttcac
    10261 caaaagaccc aatattacta attacataca cataaccggc tctagtattt aattctcttt
    10321 gtaatacatt ttcacgtata acttctaatt cttttaattt ttcttccagt tcttgaattt
    10381 tatttgcata taattctttt tccacatctg cattagcttt ttgcatatat gcgattaatt
    10441 tggaaatttc agaattgaat tgacgttgtt ctttatcaat acgtttcttt tcacgatcaa
    10501 tttctctacg aactttttcc tcttctatca tctgttcttt tattgctttt tgttgttctt
    10561 tttcttcggt aattttcact aaataagagt aatgaagttc tagttcttga agtttaaact
    10621 ctaaaagacc cttccttaat tcagcattgt cattcttgaa taaattatta attttatcaa
    10681 atatttttat gattttttcc ctagtcgagt ctatattaga aatagttagt ttattgagta
    10741 atcctttcac ttctgaatca aatggaatga gcattttttt ctttaaatta tttttctctc
    10801 gtttatttaa aataagaggg acagaaacag catcgtcaat aatatattcc ttttctttta
    10861 attttaacaa agaaagctta ttttttattt cagaagatga agtttcttct atatttgaaa
    10921 cgataagtga agaatagaca ttttttaatg tttcatcata cttttgattt atttcatcat
    10981 ttaaatcttc tttctctttt tttaataaat taatatcatt ttttaacata gtaatttgtt
    11041 tatttaaatc tgatagtgtt tcttccttac ttaatataaa tctttctcta tcatgtaatt
    11101 tatttagttt ttcatcattt ttttgttcta attcataagc ttcttttttt attgtgttag
    11161 ctttcgacag tttagtgatt cctataatta ataaaataag tccaatcaat aataacattc
    11221 aaaactcctc atttctttga tataattatt gtagagttta ctcagaaatg aggaaagagt
    11281 ccatgtgaaa gcatgggctt ttttattttt aatgttgtaa tactaaatgt tcaagattat
    11341 gaggaagccc taaatattca ataatttgga actgactcat atcagataaa tcttgttcat
    11401 ctattgttct agttaacatt tcaattgcaa acatattagc ttcagcttct ataccataaa
    11461 tcatacaact aaggttgttt gctctaaaag ctgctgtgca aataccttta tggagtctaa
    11521 cgtgggctat ttcatgccat aatacaaatc ttttcataga aggtgatagg ttttgattaa
    11581 ttaatatcac ataacatctt ttattgtgta tcgtttgtcc taatgtttta ttccctaaat
    11641 cagtttcaat taaatctata tcagaatatt tgattatttt atatggatta atcgcatcag
    11701 atccaaactc tacaaataat ttttctattt cttctaatat ccagtatttg tttaaatgca
    11761 taccaaagcc cacctattga cgatattttt taggagtgaa ttttttcttt gctttaactt
    11821 tggttaaggc aagtgcaagt tgaatggcat cgtataattt ttccttatct tcatcgtcta
    11881 aaggttcacc ataataattt gtttcagcat ctgaattcaa gccttcaagt aatttttcag
    11941 cttgtaaagc aatatcttgt ttatcttttt ctgttaaatc ataataatgg cgtttatcag
    12001 tacgtcctaa aagataatca gttgatacat taaagtaatc tgcaactttt tgtattttat
    12061 ctccagatgg agtactttta ttccatctag acatgcttcc atttccgaaa tttaactttc
    12121 tttcaagttc tgccaacgtc attgaacgtt cttttaataa gatttttata cggtctaata
    12181 gcataggata tgcattcctt tcaaaatacc gacaaaaaaa gtatttttct gcaaattatc
    12241 tatttacaaa tagagaattt gcagttatac tagttttgta agcaagatat ttacggcata
    12301 caaagactaa aagcaataaa ctaatagtct ccccagacat cagtaagctc gctttttgtg
    12361 cgctgtattt tgtatgctta cataatagca tatttgcagt ttttgtcaaa cttattagac
    12421 aaaaatatta gaaaatattc gataaggggg tatgaagcat gactttaaaa cagcaagtat
    12481 taattgcttt agtaaagaaa ggttggagtc aaagagagtt agctcgacga atgggtatat
    12541 caattactta tttacgagat atcttcatcg aaaaaagaaa acctaaggaa cgtttaaaac
    12601 aaatcgaaga acttttggat atcaagttag aagtagattc taatgatcag ccatcagaac
    12661 aggaggcgta aaaatggtac aacgtttgag caaagcggag tttaaagaga aatataagta
    12721 ttctgaaagt acttatcaaa gaagaatgaa ggaatttaaa aaatcacgtt ttagtgaggg
    12781 gtataacgca gttacttcca aagaaataac aattgatgtc gatttatatg aacagtttag
    12841 aacatggcgt tctaaaaatc gatttagagt tagagctgtt tgttaatagc taaaaaatct
    12901 aaattcacca cttctgaaaa gaggagttgc tgctctcctt tcaagtttgc caaagtccac
    12961 gttttttcat tttggcaact cctcttcttg gaggtggtga cggcgagaga cgaaggaggg
    13021 atgacatgaa ggaagaatca aaaataggga ttttgaatga gaacaattac acaagattaa
    13081 ttattgaaac agaagaaggg aaaaaagtag cagaagttac attgaccgat gcaactcctg
    13141 ctgacggtta tcgtattcga ttaactccta aatatgatta accttttggt gggtgtggat
    13201 cgtttccgtg actatcacgg ctttgaattt ttccatctct gccatgaata aatagctcag
    13261 atccttgatt tttagaaatc tctctagcga tttttactgc ttctgatttt gtattagtat
    13321 gtgcagtcgc tttagaattt ccagcacctt tgacattcca accaccattg gaattaggta
    13381 caacatgttg attttttccc atagttttca cctccatttc tatagaaata ttttatcaaa
    13441 tagaaatgga gaaattcaat aaacgaaagg agaagtgata tggcatatac cttgcaacaa
    13501 gaacatcaaa ttctcggttt gattaaacaa cgcaggaaac aattacaaga tgaccgtgca
    13561 gcgcttagaa aagccgatga gctatcagat aggcaagctg aactaattgc ttctgaactt
    13621 gaggatttga gaatgctaga aataaaaaat agggagatta gattatgaag aagacagaca
    13681 cactttttat aggattcatt ttggggttat tagtgattgt agcgcaccaa agtattatcg
    13741 ggggaagctt gttcgcagca ttgatggttt taatcaatct gcttgattca aaagaaagga
    13801 gcaactatgg cacgagaaga agcgctaaaa atcggtaaag tgattgctga taatcggtgg
    13861 ggaaatagcc gccctattat tttaagcaag caacatatcg aaaagcaaaa agcatggcaa
    13921 caaataaaaa agtgactctg ccagccagca aagagtcaca tacaaattta taaaactagg
    13981 agaattatat cacatgaata agaaaattga aaatcttatc gaagaattga aacgtgaatg
    14041 ccaaaagcaa ggtgtttcta ttatttgtac agcccaaaaa gaaggggaac ttaaaagtct
    14101 cgtttatggt gagacaacag aaattttact ttgtcttgct atgcaagaag aacatttaga
    14161 tgaaaatctc ccattgtcag cacatattat gcgtagaatt gctgtggatg cttacgaaca
    14221 agcgaaaaat gaagaagaaa atcaaccttc aaatcatact tttgttatta ataacaagga
    14281 agatttagct gatgtgatga ctcgtattct caagggggaa tttcaatgat gaatgaaaaa
    14341 acaattgatc tactcattat tttatttttc acgttagtga ttgtagcgaa aagttatgta
    14401 atctttggct tgttattcgc aattaccatg cttgtgcttt gcgtgttagc aagcagaaaa
    14461 gaggttaaac atgaacgagt tagcaaatct tgacaactat ttaactgatc ctgattatgc
    14521 taaaccacca tatgaagcac caattgatga ggaggatgaa gatgagtaaa tctaccttag
    14581 aaatgagcca tcaagaatgg cttgaagacc gtaagaaagg catcggaggt tcggatgttg
    14641 gaacaatttt aggattgaat aaatggaaat ctccttatca actatggcta gaaaaaacag
    14701 gacaagtagt acttgaagaa tcaggaagtg agcccgctta ttggggtaat gttttagaag
    14761 aagtggttgc taaagagttt caggaacgta caggcaaaaa agtacgcaga agaaaccaag
    14821 tatttgaaca tccattacat ccatttttaa gagcaaatat tgatcgggaa gtagtgggag
    14881 aaaatgccat tctggaatgc aaaacagcta atcaatttct cggtaaagaa tgggaaggcg
    14941 aagaggtacc gcttagctat ctctgtcaag ttcaacatta catgaacgtt ctaaacaaag
    15001 actattgtta catcgctgtc ttaatcggtg gtcaaaaatt tatctggaag cggattgaac
    15061 gagatcaaga gctgatcgat acaatcactg aacaattagt agagttttgg gaaacaaacg
    15121 ttcttggagg tatcgagcca attattgatg gtagtcaagc gacagctgat ttcttgaaag
    15181 agaagtatgc agatgttgaa gacgttcaaa cgacgttacc aattcatttc gatgaactag
    15241 ttgaacagaa aaacgaactc aaacggacta agaaagaaat tgaatcagct atccgtcaag
    15301 tagacaacga gattatcagc gagctaggta aacgtgaagc cagtatcggt atcactcaaa
    15361 aaaacatcat cagttggaaa tttgtccgta cgagacgtat gaactcgaag aaactagcag
    15421 agaaatatcc agatgtcgca aatgatgaag agatttataa cgttactgaa tcaagaaggc
    15481 taaccgaaag ggagatcaaa taatatggca acaaatgaat cgttaaaaaa tcaattggca
    15541 gcaaagccac agaaacaagt tgcaccaggt caattaggac ttaaagcttt gatgaataca
    15601 ccaacaatga gaaagaagtt cgaagaggtg cttcatgaca atgctaatgc ttttatgtcg
    15661 aatgttatga ctcttgtatc taatgacagt tatcttgcag atagtgaacc gatgtctatc
    15721 atgagtggtg cgttaactgc tgcaacatta aatcttgggc tagataagaa tttaggttat
    15781 gcatatttag ttccattcaa tagtaaaaac aagcaaacag gaaaatggga aaagaaagct
    15841 caattcatgc ttggctataa aggatatatc caattagccc aacgatcagg taaatacaaa
    15901 gcattaaatg tgatcgaagt ttacgaagga gaactaaaaa gctggaaccg actgacagaa
    15961 gagtttgagt ttgatccaaa tggtagaacg tctgatgaag tcattggata tgttggctat
    16021 ttcgagttac tgaatggatt caaaaaaact gtctattgga ccaaacaaga aatcgaagct
    16081 catcggattg ctaacaataa agatcgcgat aagacaaagt taagtggtgt gtgggcatct
    16141 gattacaatg caatggcacg aaaaactgtt ttgagaaatc ttctttctaa atggggaatc
    16201 ttgtccatcg aaatgcaaga agccaccaca tcggatgaga gagtccaaag ggttcaagaa
    16261 gacggcagca ttattgctga aacagaagtt gaagaagata ttcctgaaag aaaagaagca
    16321 gaggttatat ctgaagaaaa tgaagatgta caaactggat tatttgatgc atctaatccg
    16381 ccgttaaaca aataatgagg gagctttctc ccttgctttt ctagaggaga aatacgaatg
    16441 aacacaggat atgtcaaatt acatcgaaaa gtgatgaatt cattcgtttg gaccaatcct
    16501 tatatgtata aattatggaa cttgtgtttg atgaaagcga gtcatgagaa tcgcaagata
    16561 ctttttaatg gaaaagagat acaagtgaac agcggagaat tcgtcacagg gcgcgatgct
    16621 atcacatctg agatgaacga aggcgtgaaa cgtgaacatc aagtgaacag cggttctgta
    16681 tggagatggc taaaacaatt tgaaaaaaac ggaatgttga acatcaaatc aactacgaaa
    16741 tacagcgtta tatcaataaa aaactggtct ttgtaccaaa gcagtgaaca acaaatgaac
    16801 atcaaacgca caacaagtga acaacaagtg cacacaaaca agaatgaaaa gaattataag
    16861 aatgaaaaga ataataaaac atcatcgtcg caaccacgca aaaagcgtgt ttacgacacc
    16921 gactcagttt actacattct cgcggaggag ttattcaaac agatttgtca gaatcaggaa
    16981 atcaaaaagc cgaatctgca aagttgggca gataacattc ggaaaatgat cgagatcgac
    17041 aagcggaccg aaaaccaggt acggggaatg attgaatgga gtcagcacaa tgtgttttgg
    17101 gcatcgaata ttttatctgc taaaaaattg cgagaaaaat acgacacaat ggcagcgcaa
    17161 gccaatcgtg attataaaac aaaacaaact aaaacgcttg aatacgagaa atttagcaca
    17221 gatgagttgc ctatttgaga ggaggcgtag gcatggaaac tgttggggaa atcatggaaa
    17281 agctgataca gaaagtgctt gtccaacgtg gcgaatgtcc tgaatgcgga cagcctttgt
    17341 atggatggcg tacgaagaac cctgatggct cagaacgttg taagccaacc tgtatgcaat
    17401 gtgggtataa agcattgcga gttcaggaag acttacaaac agaacgaatt tacaacgaga
    17461 gcctgaaagc aagagcaatc aattttttca aaggtggttc tgttgtgcct aatcaagcgt
    17521 tgtttgattg cacattgcag aattatcaaa ttgtcgatca agaaacaaga caagcggttg
    17581 aagtaaccaa acgctttgtt aattcagtct tgttaggaaa tccaagtcac cttgttttaa
    17641 ctggaaaaca aggaacaggt aaaagtcacc tagcgatggc agcggcttgg gaagtcttga
    17701 agcgatcaaa ctacgataaa aaaatcttat ttatcgggtt acaggaaatg ctggatcaaa
    17761 tcaaattttc gtacaacaat cctgaactca gaaaaacgat tgagggatcg ttgattgcag
    17821 atatcaaaac agcggattta gtcatcattg atgatatcgg ttcagaacta ggaaaagatg
    17881 catcagatag tcgagcgttt ggcataaaca cgctaaattc gttcttggat gcacgacaga
    17941 acctagcaac gattatcaca acgaacttgc ttggtgaaga actgaaaaaa gcttacggta
    18001 cgagaacaat atcaagaatg tttgtcaact ctgatggatt tacgatggta ttttctcaaa
    18061 cagcagacaa gcgcataaaa ccagtcaaag gagcgatcgc atgaatttga ctaaacaaga
    18121 aaaaagaatc tgtcgtcaga taatgttgca aattataggt gatcgtgaca tggacgaatt
    18181 atctcaacaa gagagtcgaa tggttcggaa gataagtaag ctaattattt atcgggatac
    18241 agaaagattt ctcactgttt taggtaacgt ctacgagaat ccagagttat tggaggtaga
    18301 gtaattgcca aaaatattag atgcatgttg cggtagtaga ttgttctggt ttgataagaa
    18361 caattctgac gtaacattta tggattgtcg tcagcagtat gaagaattat caacaggtca
    18421 tgtgatcaat gttgatccag atgtggtcgc agactttcgc gatatgcctt ttgaagatga
    18481 tgtgttcgat atggttgtat ttgacccgcc acacttaaga catgtcggcg aaaactcatg
    18541 gcttgccaaa aaatatggaa aattagacga actttggcca gaagacatca ggcaaggttt
    18601 tgcagagtgt atgcgagttt tacgaccttc aggaacatta atttttaagt ggaacgagga
    18661 acagatacca ctttctgatg tgttagaggc tattggagaa cagccattgt ttggtaataa
    18721 acgaagcaaa acacattggc ttgtgtttat gaaaaaattc agctaacgga ggaaacaaag
    18781 gaggaaaagt aatgaagatt gtattaaata aatgttttgg tggctttggg ttgagccatg
    18841 aagcaaaaat ggaaattttt aaaagaaaaa atattgaagt attcccatac atcaataact
    18901 ttagctatga ctcagatgat gaatacacga gatacacagg ccaaaagcta ggttcgatgg
    18961 attttatcta ctatttcaaa aaagacccga aaatcgacaa agttacagga atttatagcg
    19021 aaattgaccg actgtacgga attgctgatg attccagttt ttcaagtgat tcaaacagag
    19081 gtgataagga cctcgttgct gttgtcgaaa aactaggaag tgaggccagt ggaccatatg
    19141 caagtcttaa agtcgttgat atacccgatg gggctgagtg ggaaataagt gattatgacg
    19201 gcgttgaaac tgcacattat ggttttcaaa caggtagtat ttagtccact aatgacaact
    19261 aaagaggagg cagaaggatg agtgaagatg aatactttga acagtagtct attaacgaca
    19321 gagattttta actggaaagg ggtgtagtca tggacgcatc ggaagtagta aataaaatta
    19381 atagtctcaa agaggttttc ggagacgtcg aagtagtgat aaacgcacaa ggctatgaca
    19441 acggattttt taagcagatt accgacatta gcattcagca aggaatggaa gacgaagatg
    19501 gaaactttat cgatgaagta gccattttag tgacttgcga gtaagtaatt gacagctaaa
    19561 gaggaggcag aaggatgaaa aaattgcacc aactcatatc tgagaaagaa agcgaactcc
    19621 aaaatttaga agatagtttg ggattggggt ttccaattgt tgagcaagct aaaatgactc
    19681 aaatcagtca tctacgactt gaattggaag atttaagaca aatagaaaaa tcaattcaac
    19741 tcaacgacaa ccagaaaatc gtgttggagt ggttgaaaag cgagacaatt ttaactagag
    19801 aagcaccaat attatctgtt aatgcttttt ctgataaaaa tttactagga aaattacctg
    19861 ataaagtacg caaagcttat aaactattgg cttgtaaaca agaatatgaa gtcctatcag
    19921 cattcgctca atggggatta gaacaggagg aagcggaatg aacaacagac atcgcagaat
    19981 aacaaaacta agaaaacagg aactgaatgt actaaagaca aagtttgaaa aagaatatgg
    20041 aatttcagca gaagaaacat ataaagtggc aagtcagttt gttgctgatg cgagtaatgc
    20101 tattcgtaag tttgggattt cgatattaaa tgatgatcgt aaatgggagg aaatgagatg
    20161 aaaataaaag acggatttta cgctagtagt catggtatcg gcggtttaat gctagacatg
    20221 ccgataaaga accctaaaac acgtcagaaa tcaaaattca aaatcggtga catggtccga
    20281 tgtaaagcag aagagttcat ctatccgttt cgtggatatg tagagcatgt ctataatcat
    20341 tcagcaatca ttcacattga aaacacgatg gaatgcgata agtggttagc gaaaagcaaa
    20401 gataatttag cagtggctcg tttggtggat atggaactaa tcaatgacaa ataaaaaagc
    20461 cggatcgctc cgactgattc aataaatcca acacatttat tatatcacat aaaggagcgg
    20521 tttgacttga tgcaattgtt acgagaggta gatttcaaac agacaagatg taatgcgaga
    20581 gatgtgctga agaactttcg gcgtttggag cggatggcag gtcgctcttt gatagatatt
    20641 aagtcgccga ttattacgga tatgccgaag gcaccgaagc acggcaataa ggcagaagac
    20701 gcgatcattc agatgatgga tatagaagcg gagagagacg caatactagc ggctttgatg
    20761 gctcttagtc tgattagccg tcagatactc tactacagct tctgtgacgt aaacaagcac
    20821 tctaattatg aaatagggca attgatacga ggatacggag agaagaatgt agagaagttg
    20881 aaatccatcg cattaatcga atttgcagaa gcatacaaaa aaggcgtgtt agttcagtat
    20941 cgttgatttt gtagggtttt tgtagggata gtgtagggtt tttgagcggt ttaacgtgat
    21001 attatggtag tgtcgaaaga ttagtgatag gtctgagaca aaataaaatg taagggagga
    21061 aatctccctc atcgttttaa cttaagcttc gatagacagc aacggaaata ttaagaataa
    21121 ggatgtgaat ttcaactcct tctaaattgt tcttattatc tatcatccgt tgttgtctat
    21181 taatttatgc atcggaggaa aaacgaatgg ataaagaaat caaagtaact gtcaaattag
    21241 atttgactga actaaaagaa ctgctcaaca aggctagtga ccaagtcgaa cagttacaag
    21301 aaactttaga tgaaattgct aattttaaaa tccaagtttc ttagcagtat attttttagc
    21361 agctgcactc ataaaatcat accaagtatc agaaaaatat aacttaacta aataattaaa
    21421 aaaggtgggt aaatagaaat gacggcgtta ataatttcaa tttttgcgct ctgtcttaat
    21481 gtctatatga ttggatttaa aaatggacaa aataaaaaat agtagcagcc gagaataatt
    21541 ttatagtgtc actgtggcgg aaatagaaga cgcaaaggtg gaggtaggaa gcgtatggcg
    21601 cactatcggg accttgtaca aaactagaaa ggactagtac gtgtgtggtg cgagccctag
    21661 ggaggaacag gataaccgcc tgtgtgtagg ttgctattac atattagatc actctttgag
    21721 tggtcttttt atttacataa aggaggctac ataatgagaa actactggta tatatcgcta
    21781 actaatgaat atcctcgaac cattgatgat tgttcagtgc gtgttgtgcg ttctgtccaa
    21841 atcaaaaaga agtactccat tgttgaaatg accagagaag ctacgccaaa agagattgat
    21901 aaatgcaaac ttctttattg cggtcatggt ttctatgatg aaccaaacat tcaaaataat
    21961 attaacaaga atttgaggga ttagaatgca agaaatggct taaaaatctc caatcaggac
    22021 aaatcaagtt agacaaagtt tccgatttaa agatattgat tgaagctgat ttaatgctaa
    22081 aagatattga aaattagaaa acaaaactca acctaagaag attgcgaggt ggtgtgtatt
    22141 gaatggcaag acaacgtgat ccaagacgtg atgaagccaa aagaatttgg ttagaatcca
    22201 acggagaaaa gcagttaaag gaaattgcat ctgaattaaa tgtttcagat tctcaggtta
    22261 gaaaatggaa atcgcaagac aaatggagcg ctgaattgaa aagtaacgtt accaatggca
    22321 aaagtaacgt tactaatcaa ggtggcgctc ctattggtaa tcaaaatgct aaaggtaaca
    22381 aaggaaacag cagagcatca ccgccaaaga gaaataagaa tgctcttaaa actggtgagt
    22441 atgaaacaat attttttgac acgttaaccg ataatgagaa ggacatctat tctagtttga
    22501 atgatgatcc ttcttttgct ttgtccgaag aaatacgact tcttaaaata agacaacttc
    22561 gaatgatgaa aagaatccaa caagctgaag ctggactaaa tgatgaagaa gtcgaacgat
    22621 tgcagcagct aagaaagatt aaaactccga ttgaaaaaaa tggtaaaaag ctagaaatca
    22681 agcgtgaggt tatgcaagat gtgcagatta gcagaaaaaa acatcgcaaa attgatgata
    22741 ttctttcaat tgaagattca ttgactcgga ttagcaacca gttagctaaa gccatcaagc
    22801 aaatgaatga actttatatg aatgaataca gaactgattt aattaaagct cagactgata
    22861 agatccaagc tgagacaaat gaaattggcg gaaataattc aggtgaagaa atagaagaat
    22921 ggaaacaggc agttttaaat gccgcaaaca aacgggcggt gaaagaaaat gaataatgaa
    22981 tttattcctt ttgctgatat tggttctgcc attgattatt actatgataa accagtagct
    23041 ttttgccaag atattttgca tttgaatcct gatgaatggc aagaaaatgt tttaaatgat
    23101 ttagctgaat tttcaaaggt ttctgttcgt tctggtcaag gagttggaaa aacagcatta
    23161 gaagcaggag caatactttg gttcttaacg tgtcgaccct acgctaaagt aatagcaaca
    23221 gctccgacaa tgaagcaact ttacgatgta ctttgggcag aggtagctaa atggttaaat
    23281 gatagcttga tcaaaaactt actgaagtgg acaaagacca aaatttatat ggttggtgat
    23341 tcagagcgtt ggtttgctac ggctagaaca gcgactaaac cagaaaatat gcaaggtttt
    23401 cacgaggacc atatgttgat tgtggtagat gaagcttctg gtgtgtctga tccaattatg
    23461 gaagctattc ttggtacgct atcaggtttt gataataagc tgttgatgtg tggaaaccct
    23521 aataatattg aaggtgtctt ttacgattcc cacaattcag accgtgataa atacagagtt
    23581 cataaagtat caagctatga tagtaaacgt acaaacaaag acaatataga aatgattctt
    23641 aaaaaatatg gaaaagaaag tgatgttgct cgtgtccgta tttttggaga atttcccaaa
    23701 ggtgcgttgg attcatttat cagtcttgaa acggttgaat tggctacaga aaaacaaatt
    23761 agtgattctt tagtcaataa aacaacggtt gctcatattg gtgttgacgt agctcgatat
    23821 ggtgatgatt ctacgattct ctttcctaga attgctacca gggcattgga gtatgagaag
    23881 tattcaaaac gtagcactat ggaaacaaca ggatatgtca tcaacatggc caagaatcta
    23941 atgagtcaat atccgagtat tgataaagtg atgattaaag tcgatgacac tggtgtcgga
    24001 ggtggtgtaa ccgaccgcct agaagaactt atagaagaca agcattatcc ttttgaggtg
    24061 tttggagtga ataacggttc aacatcagaa gacgattttt acgataattt aggtactcaa
    24121 ctatggggaa acatcaagga aatgttagaa gaaaatatga cagcaaatct taacggagaa
    24181 cagcctgtta ttgaattgcc ttctgatagt tcgttaatca aagaattaag tactcgcaaa
    24241 ttcaaaatga caagtagaag tcgtatacgt ttagaaagta aagatgatat gaaaaagcga
    24301 aatattggta gtcccgatat tgctgacgca ctggctttag cgttttatga gccaccaagt
    24361 cactatcaat ttattcaatt ttaggaggtg agtttttgat tagtacagta ttatctttag
    24421 agagatataa gaagctacgt gttaaatatg caacacaaat tgaagatgga atgtttgatc
    24481 cgaatggttt tatagaatat atgaaaccat tttttgctga tcgcgaaaga aaatatctag
    24541 cttatactag cgaaaagaat gaaatagaca atagaccaaa gcctaacact gatattgtaa
    24601 aagttaataa taaacttcat gctggtatgt attcaattgt cgtagaccaa gcagtcaatc
    24661 attttactgg tatacctatc aaatgggatt acgatgtatc ggaacaaaaa agaacactca
    24721 ttcaaagatt aaaagataaa ttcttaaaaa atgatataga acttccaaca gttccagaag
    24781 cttttaacaa attaacaagc aatcttgatt ccatgagatt cgcaatgctt gattctgaaa
    24841 ctgcaacttt tcaaggagct tgtggagtag ctttccgatt gttagagcct gtggaagaag
    24901 atgatggttg gaagttaaga gcaagtaata ttgaaccttg gagagcagaa agatatggaa
    24961 atgccggaat ctatatcaaa gaaaagtatg actcttacca gaaaaaattt tttcaagaaa
    25021 tgaaagttat gacaagaaat aaaattctga catatgcttg ctatggtgat ttgaattttg
    25081 ttacaagcgg aacgttcaaa aaaattgatg agaccgataa ccctttgggg acgattacct
    25141 tggcagaatt taaaaataat acgaatcgtt attgtgattt tgaagtagct gaggaaattg
    25201 gagatgcaat tgatcgtgct ttgtctgatc aacaaaacga aatcgaacaa tttaagcttg
    25261 cgtacatgct tgttactggc acaacaatga gcaaaggcac tgctaaagaa atgatgaatc
    25321 agctagggat tatcaactta aaagacccta ctgcaaaagc tgaatatgtc acaaaaaaat
    25381 tagcaaaaga tttcaatgaa tatcatatgg atctattgaa aaaacagttt tacaccattt
    25441 gtaaagcaat cgattttaac gatgaggtgt ttaaatcaaa cagttctgga gaagctcgca
    25501 agtggcaaat cattagccta gaagcgaaaa caaatactaa agagcaatat tttagagaag
    25561 gattgaaaga atgcgcagaa acaattgctg cttttcttaa gtttcatgac aaagtagaaa
    25621 ttgagcctga aaaaattatt tttactttct ctagatcttt gccaactgat ttaagttatt
    25681 tagctgaagc tttacctaaa cttgcaccat acgtatccaa acgaactatt cagagccaaa
    25741 ttccatttgt aacagatgtt gattatgaaa atgaaatgat ggaattggaa agtggaagtg
    25801 cttatccaga tagtgaatac aattttggcg gaggtggcaa tagtgacgat agaaacgaag
    25861 tattggacca aacgtcgaga actggaggat caagcaaggc tcaaacaaga aaatcagaca
    25921 cttaaaaaat taactagtgt atttcctgaa gcactgaaag agatacaagc aaaactatta
    25981 tcacaagctg acttacacaa tatcacttat ccagaaatga tggagtttta cagtacaagt
    26041 aatcagaaaa aatatcgtga atatgtggaa aaaaattata agtcattaaa aatgtatgat
    26101 gcaaaataca aagagtttat cgatgaattt tttccaccat ttgactatgc aaaagtcaat
    26161 cgcttattac aaatacgatc agatgtattt aaaattcttg cagaatatgc gatggatgca
    26221 gatgtgaatc aatatttttc tgatcgctta gaggaaattc ttcaaagaac atattcttct
    26281 aatgctaatg tttttgttca acttttaaac gttgatatac caaattattt accagaaaat
    26341 gaaattaaac attatttgaa ctatccatgg tcaggaaaga cattttcaag aagactttgg
    26401 ggaaatattt catcgcttga acagaaactc tctaatgcta ttgtaaaaag tgttgctagt
    26461 ggagaaggcg ttatacacgc attaaacacc atgagattag actcagaaat ttgtgacatg
    26521 tttaagttag aagaatcaaa gtataacaaa gcgatagaaa atctcgttcg aacggagtat
    26581 gcaaaatttg cacaagatgg tattgaaaaa tcatatttag aaacaggtat tgaggaatac
    26641 aacgtattga ctgcaaaaga tgagagagtt tgccggattt gtggaggaaa ggcaagtaag
    26701 aatccctata aactgaaaga tgctgtcata ggtgaaaatc gagcaccttt ccatagtcgt
    26761 tgtagatgta cggatgttcc taatttacca aaattaggaa aggatattga tgaagaatat
    26821 gaccgtttat ttggcgattt attagatgag tttgcacatg attcttttgg aattaatttg
    26881 aaacggagga agtagaatga aagatttttt tgaagcagta ctaacaatta atgtaaatgc
    26941 tgatattgca gaagcctaca aaacagctat tgagtctgag aaccatccta atggcttgag
    27001 agaccattgg aatggcaatt atgcctacgt ggttattggc gatcaaactg ttaattatca
    27061 agataatact ccagttgata agaataccgt taatttaacg attcaattat tatctcattc
    27121 attaccaaat ttaaaagaaa cagttgattg gtatgaaaag atgggatgta ttgttgttag
    27181 aactgactac aaagaaggaa agtctagtaa ttaggctttt ttattttgtc cgaaatgacg
    27241 ttaaactagc gcaatactgg gcttggttga atggtggggc gcaactatta aaactcaaag
    27301 caatgcgggg cgtgaaaacg aatcgtgggg cgaaaggaga atgagcatga aacacaaatc
    27361 attaatgcca atgaatttgc aatactttgc cgaaggtgac gatcaaaagt tttcttttga
    27421 tgacttcaaa tcttttgtgg aatccaatga agaagctcaa aaatttattc agtcacaatc
    27481 tcaaagtgtt gccgacaaac aattggaagc ttggaaacaa aataacttag ataaaattaa
    27541 acaggatacc atcaaggaat atgaggaatc taagaaaaac aagtcacctg agcaaattca
    27601 actggaaaaa ctacaagctg aatttgaagc agaaaaagcg ttgcgtgtga caagtgataa
    27661 taaagcattt gttgcagaac aaattgctgg attagaacta gatggagagt taaaagagtc
    27721 tatttctcaa tttatgctaa ataatcttgt tagttcggat acagatttca ctaagaatgc
    27781 tgttgaaggt tttacaagtg ttttgaatgc aattaatgag aaacatgcag atgcattaaa
    27841 agaactacaa atgaagtctg catttggtgg aactcaacaa tcgaataacc aggttcagca
    27901 gaacaatgaa acattaacaa atccagaaga acaattagga caaattcttc aacaatttaa
    27961 ctaggagagt gaaaaattat gaaaaaaaca tctttaaata atttagagta tttggatatt
    28021 tcaccagcga ttaatgctat gcaagtacca aatacacctt ttttaagcta tttacttggt
    28081 gctggaaaaa cagagccagc aaactcgaca gaaattaaat ggcgtgaata tgatatcaac
    28141 aacgatgatt cttctgaaaa acttgagggc ggagaatatc cagatgctga atcaggtcga
    28201 acttggttta acaactatac tgaaattttt agaaaatcaa cctctgtatc tggtacatta
    28261 gatgctatta atgtgaatgg agtcggaaat gaattaacta atcaagtagc actacgtggt
    28321 atggaaatga aaattgattt gaaccgaaaa ttgattactg gtgtaaaagc tgatgaaaat
    28381 ggttctaaag gtcgtcgaat gaatgggatt ttgaacttga tcaattcagc aaataaggca
    28441 gaaacagcca ctgcgggtgc agtaacaaga aaagatatcg atactttatt taaattgatg
    28501 tatgaaaaag gttatatggg agaaaaacta tgcttgattt ctccagatat gcaggagtta
    28561 atgactgatg agttagatgg aaaatcaaca aaaattgttc agttcgggga aagagtaact
    28621 tttggattgc aaattggaaa tatcgtgtct aattacggta caggtattgc tctactagaa
    28681 ccatcattgc caaaaggaac aattgccgca atcgatacta attatgtgaa actacgtcca
    28741 ttacgtgaat ggagagcaga agaacttgca aaaacaacgg attctagacg tatcggtctt
    28801 gtaggtgaat actctcttga atacaatgct tcaaactctg gggcaatttt aaatttaaag
    28861 tctgaataaa agggagttag tactcccttt tttgatagga ggaattacag tggtaaaaaa
    28921 agatgaaact aaaaaagatg aagtcgtgaa atatagagta ggtaaaacta aaaattttgt
    28981 tgggtttgtt catcctaaaa ctcgtagatt tatcacagca gattcaaata acgaatttat
    29041 catttctata gatgataaag aagcaattgc aattttggaa gatgcaattg atgttaatga
    29101 aatttaggaa gtgatctgat ggatgaatcg ctaaaaacgg aaatcattga gtctacaaaa
    29161 gaagattttc cagatttgag tgaagaacgc ataactaatt tattagaaat aattttgcta
    29221 gaaattgaat catacaacac ttgtaaaaat gatatttcat gggaaaagtt aaaaagcgtg
    29281 attagtgaag tgttgtataa aataataaaa aatgaatcag aaaaaacagt atcttcagtt
    29341 agacgtggcg atacaacgat tagttatgct tcaacaacaa atgatgttag tgagttactt
    29401 ctaggctatg gtgatttgat acgaagagtt attggttgtg gaggattgga gtttttttaa
    29461 tgaatgaagc agatatttta gaaactactt atgaagatag ttgtattatt gaaagactga
    29521 cggacattga agattctaat acaaatatta ctattcaaga ttacaaaaaa gtatatgata
    29581 atcctatttc ttgcgctctt tcacaaggtc aaatcgatgg actagcagtc atagaagatg
    29641 gagagatggt aaatgtttca actgacacat ataaattatt tgttcatcct aagattaaac
    29701 taaaaaaagg agatcgaata acaataactc aaaaggccag tggcttaatt ttttctctat
    29761 ttgctactaa gcctttttac tatcctagtc attgtgaagt gaatttgata ggaagtgaga
    29821 aaaatgggta atctcaaata tgaatcaaat gcagaaaaga tcattgagaa ttttaaaaat
    29881 atgactgtaa ttgctcaaaa agaaggaata tccttcgtta acgattcaat gaataaagtc
    29941 gttagtttag ctaaaccatt aactcctgta aaatcaggta atttaaggcg aggatatcgt
    30001 gtagtaaaag ctagaaaact atcaagcggt cgaattgttg gagcagttat aaacaatgaa
    30061 cattatttta aatatgtaga agaaggtcat aggactaaaa atggtggctt tgtcaaaggg
    30121 aaattcatgt taactcgtgc aacgaatctt gcaaatatgt cttatattcc tcgaagattt
    30181 aaacaaatgg caataaaaat cgttaagaaa ggaaagtaac atgaaagatg aaatcattgc
    30241 tgcaatcagt agcaaattaa aagaaatcta tcctgatggg acaatatatc ttgattcagt
    30301 tatgcagtca actaaagatt tttatttcgt tttatcagta atggaatctg gaactgaaaa
    30361 tgtaggaatt gatattcaaa atgtttcttt cttaattgat attgcattga ttgataataa
    30421 acctaataga aatttaatta atgaattagt ctcacgttgt gggacttttt ttaatacgat
    30481 tacaatcgat gagcaaatat tatttccaaa agcctattta cctgatgaag cagatggtgt
    30541 tcaacatatt cgttttacat tagaatttcc acaatatatt gaatggagtg aaagataaat
    30601 gggagaaaaa agaagtaaaa ccggaattat ttctgtcgaa aaacctactt ggtttccttt
    30661 ggaagatgag acagggaatt ttccggtata tggtactgcg ttgccaatgg gaacagcagt
    30721 aagtatcaaa ccaacagcta attatgaaac aacacaagat tatggggatt cagtggttca
    30781 agatcaattt acagcttttg gtggtgcaga agttgaactg gaagcaaatg gatatactca
    30841 taaagtttta tctacaatta ctggagggaa aattgttaaa ggtggtgcct tgcgttctgg
    30901 agaagatatt gcgcaagatg gtgcgtttgc atatagacgt aaaaaatcga atgggaaata
    30961 ccgttatacg gtcttttata aaggacagtt tgctctagat tcagatgaaa catcaacgat
    31021 tgaaggaagt aaagtaagtt ttactcatcc aacttggaag ggttcatttg tagatgtacc
    31081 aggacttgga tatatgtatt cagttgatga agatgatgaa ggcgtggata aagcaatgat
    31141 cggaaattgg tttacaaaag tagcaattcc aattgaagaa gcagaacttt caggaggtac
    31201 agaataatgt caaaatatca aacaacgatt aaattaacga aaaaagatga agaaggtaaa
    31261 tatgagcaag tacaatttaa atctgctgaa tttctaccag gcccagtcgt agaagaagca
    31321 gcagaagtaa tggagggaat gcaaaatgct gtagatggaa aatcagtatc agaagcatta
    31381 agtcgagctt attcatttat tgcagatatt ttgtttgaag gacagtttac tggtgaagat
    31441 tatcgtcaag ggatcgatgc tcgagaaatt gcttcgttga caggtaagtt attaaaatct
    31501 gttactgcag gctttgatga aacttataca gaaacgaaaa aaaagtaagc gaagctctca
    31561 aatatccttt ttttaaacat tcgattactt atcgagaatt agatttaaag acgcaattac
    31621 tcgaagcagg ttggacgtta ccagaaattg aacgtactga ctttgacgag ttaatgcgtc
    31681 tttttgcttt tcgagatgca gtaaaagagc atgaggatgt tgagtactac gataacttca
    31741 cccaatttta ggaggtgata ctttgaataa cgatgaccta attctgaaga tgatactaga
    31801 tgaatctggt tttactgccg gtatgaataa tgctgtcaaa aagttgaact cttttgatga
    31861 aacaatcgaa agaaaaagta gaaatagtgg cagttcatta ggtagtattt ggaaaatatt
    31921 tgctggaagt tttctagcta gcggagtaac tagaatcgta ggagctggct ttgatctaat
    31981 caagggttcc ataagtggag cggttgatcg agtagatacg atgaataacg ctctacgaaa
    32041 tttccaaaat atgggattta gtaattcaga aattatgaag aatatcggaa agaatgggct
    32101 tttatctcaa ggtattcaag gacttcctac tgctttgaat gatgcgataa gtcatgttca
    32161 acttcttgct tcttctacag gtgatttaac tcgttcaact caaatattta aagctttaaa
    32221 tgatggaatt cttggtttcg gtggttcaac tgatcaagtt aatgaagctg ttattcaatt
    32281 atctcaaagt ttctcaaacg gaaaagtaga cgcacaaact tggaactcaa tgatcaacgc
    32341 tcaacttgga cctactcttt ctgctattgc taaaaagatg ggaattacaa tgggagatct
    32401 gaaagaaggt ttatctcaag gtaagatttc tgttgaagaa ttccaaaatc aattaataga
    32461 aatggatacc aaaggtggcg gaggacttaa atcattaagt caaatcgcta aagattctac
    32521 taagggaatt aaaacctcta tacaaaatgc aaaaacagct gttacacgtg gtgttggtga
    32581 ggtaatagaa ggattaaata aagcattagt agattcagat ttaggtggat ttaagggaat
    32641 tattgataaa gtgggcagtt caatggaatc gttcttaaaa gtaattgctg caaatattcc
    32701 tacagcagta tcatttttaa gtaatttatt taacgaaatt caaaaatttg gttctgcttt
    32761 gaaattcatg atgccctttc ttgttcctgc agctaccgct tttggagcgt tcatgtttca
    32821 acttaaaggt ataccagcaa taataaaaag cttcaataat tttaagaatg ccataattgg
    32881 cgttggaaat tcattaaaga ttatgggggc aatagctgct gctaattcat ttgttttaat
    32941 tattggtgca gtcgttggtg caatagctgt tttcggttac tttatggcaa ccaatgaaga
    33001 gcttagaaac aaggttatat ctatttggaa tgatgtgaaa gattccgtaa ttggtgtatt
    33061 aaaaaatata aaggactggg gaattgatac ttggaattct gctaaagaaa tggcatcaaa
    33121 tgcagttgag ggtgtcaaag atgcttggtc aggaacaaag gaatggtttt ctaacacctg
    33181 gaaaggtatt aaggatgggg ccacaggttt atttgataaa acagtagaga cttcaagaaa
    33241 tgcagtcgat agtgtaaaaa atgcatggtc taatatgaag aaatggtttt ctgatacttg
    33301 gcaaagtata aaagattcag ccagagaaaa atggaatgga atcaaaggtt ctattatgtc
    33361 agttgctggt ccattgatta caggtataaa gaatgcattt ttacatgtta ctttttatct
    33421 agagacctta tggaataatt tagttgagat tggtaaaaac gtctttgaga ttttaaaaaa
    33481 tgttatactt gcgccggttt tgtttattac ctccatgatt tctggtggat gggaagaaac
    33541 aaaaaataat atgattgctg tttggaataa tattaaagaa agtgccataa atatttggga
    33601 atctataaag aatatatttg taagttattt tacaaatatt tattttgctg cactcaatat
    33661 ttggacaggg ttcaagctta cattgataaa tatttggaat gaagtggtaa atcaagctaa
    33721 atcgatttgg ttaaacataa agtatttttt tattaatctt tggattgata taaaatattt
    33781 tgcaattcag aaatggattg aattgaagtt ttctattatt caaacttgga tcgatttaaa
    33841 atataatgcc attactactt ggaataatat taaacagttt ttcaaagata cttggaaaaa
    33901 tattaaagat acggcataca atacgtggat ttctataaaa aataccatga ttaatacatg
    33961 gaataacatt aaggactctt tctggaatat tgttactgga attgttaatt ctgctgaaaa
    34021 tgcatggaca aatctaaaaa atggtgtttc aaatgctatt aatcgggtaa aagaaatctt
    34081 taattcgtta agggaagtca atttatttga aattggcaag aacatcattg atggacttat
    34141 aaatggtgta aaagaaaagt ggaatgcttt gaaagatact atcaaaggta ttgcaggtaa
    34201 tatcaaaaat tggattaaag gagctttaga tattcattct ccatcaagat ggatgcgtga
    34261 tatggttggt aaaaatattg ttcaaggtat tatcgttggt attgataaag agcaaagtaa
    34321 gttagatcaa accatgacaa atttagtaaa aacaccgtct gttcaacctg tagtaaatgg
    34381 aataagtcac ctaccaatta cacaaacaaa gcaaaatata tctgctagtg aaacaaaaga
    34441 aattcattta catttaaatg tttatggaga tttacctgat tcaatggttc gaaagattac
    34501 tacaaaaatt aaaacagaat tgacaagaca aatgaaacga gatgctggtg cagtaggagg
    34561 aacattatat gcaacttaag agaggacaat tttttattaa tcaacattat tcttctgaat
    34621 ttaatgtgta tattcaaaac aggcctgctt ctgtttcagc tagtcgagta attgaattga
    34681 gagagcgaga aggaaatgat tctatcatta ttgataaagg ctattacaaa aatgtgacta
    34741 gaaagattga gtgttactat aaagcacctt caattgatat ggtgcaggag tgggaagatc
    34801 gaatcactga atggttagat atgtcgtctt atagtgattt tattctttac tatgatgaac
    34861 aatatattta tcaagctgta gtaatagaag gacctgaatt taaaggaaca agaaaaacag
    34921 gaaatattgt cccttttgaa tttacagtga gtattcgacc atttaaggaa aattacaatg
    34981 gtagatttac tattcgacaa acagaaactt ttgaaattta taacccagag aagtattctt
    35041 caaaaccgct tattaaattg agtggttctg gagatgcttc tttttatatt aataaggata
    35101 aatatgattt gaaatcgttg gacagagaat tatttataga ttctaaatta gaagaggctt
    35161 atcgaaaatt agatggtaat ttagaacatc aggatcaggt caccttattt ttagattttc
    35221 catttttata tcctggaaaa aatgaaatta aatggacgaa aaatattcat tcatttgaaa
    35281 taatgcctag gtggtggaga aaagtatgaa accaagaata tatagtccta ctgaaacaga
    35341 tttctcaacg aatggcttag gaattttaaa ggattgtaca agatgtgaaa tatatgaagt
    35401 agctaatgga aaatatgaat tagagttgga ttatccttta ggaactagat ttgatgaata
    35461 ttttgaaaat gactatcaaa taaaagcaaa gccaaacgat caagaagagt atcatatctt
    35521 ttttattgat gataaagata tagatacttt tttaaataca gtaactattt atgctcagag
    35581 tcgtacaaat cgacttggaa gacgggtagt cactcttgtg gaagtggact ctaaaactgg
    35641 tcaagaagcg atatcaatta ttgaaactaa aatggataaa aaatctgaca tacgacttta
    35701 ttctgatatt acggctgttt ctagcacaat ctttgaagcg agaaatgttt taaattgtat
    35761 tgctggtgaa caaggatcat tgcttcaata ttggggcgga gaaattaaac gtgaaccatt
    35821 taagctttct ttgttaaagc gaagaggtcg caataatgtt ggaacgattc ggtatggaaa
    35881 agatatgtct ggtttgaagg tcaaattaga ttggacaggt ataaaaacaa gaattattcc
    35941 atatgctgat cctcaaagtg aagtaggtac gactaatcga atttatggtt cgccagtaga
    36001 tagtgcctat attaataact atcctgatgt ctatacagaa catgttcagt ttacagaaga
    36061 acaaggagta aaagacatta agagcttaaa taaaatagct aaaaattact ttaaaacgat
    36121 caatcctggc tgtgataagc ctaaagtttc tattacggtt gaatttgata agttgactga
    36181 tagtgaagaa gcgaaagaat ttgcgaagat tagaaattat ggtctgtttg atacatttaa
    36241 aatatatcat aaaaaatata atatttatct tgaatcaaag gttagtggac tacaatacga
    36301 ttctttatct gaaaaaactt tgaaattaga agcaggagac attcaagttg ctttttatca
    36361 gcaacaagct gtaactattc aggataaatt aaaagattat gcaacgaata attatatgag
    36421 tgattttaat gattatgttt cttcaatgat tacaggtcaa ggcagtgcag gaggatatgt
    36481 agttttatgg ccaaaagaaa aaccttccaa catctttatt atggataatc cagatttaga
    36541 aaaggcaaga gaagtactaa gaatgaataa aaatgggatt gctttttcta agaaaggatg
    36601 gcgggggcct tttaattcag cttggacatt agatagtata tttaatgcca attttataca
    36661 aactggatta atcaaagcag atatctttca aaattctttt aacaagactg gagatgtatt
    36721 gaaattagtt aatggactac tccaaatttg gaacaacaaa aagaaaataa tggagttaac
    36781 taaaaaagga atggaatttt ggaattctaa gggttcaatt ggaacgattg gaacaactga
    36841 ttctgttggt aatccttttc ctggggcttc tactccaacc cctattgaag ataattcttt
    36901 agttattcgt acaaatggag acggcaaata tattttgatt tctcctaaag taggaaaagg
    36961 attagtttta ttaggaaatg gtaaagcaat ttattttgga gacttagatg tacaaggaaa
    37021 acttacagtt aaaggaaaag aaataattcc tggacaaggt ggtggtccat cgggaggtgg
    37081 agaatctact ggtgggtatc ctagtgaatt aaaaacagat gcagaaaaga gagcttggag
    37141 aat
//
LOCUS       DBBGSP010000025        35438 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000025 DBBGSP010000000
VERSION     DBBGSP010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.025"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..1152
                     /locus_tag="ACIZE9_001510"
     CDS             <1..1152
                     /locus_tag="ACIZE9_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HGC6093374.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="ACIZE9_001511"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="ACIZE9_001511"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGC6093375.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="ACIZE9_001512"
     CDS             2728..3003
                     /locus_tag="ACIZE9_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGC6093376.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="ACIZE9_001513"
     CDS             3009..3776
                     /locus_tag="ACIZE9_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGC6093377.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="ACIZE9_001514"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="ACIZE9_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGC6093378.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="ACIZE9_001515"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="ACIZE9_001515"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HGC6093379.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="ACIZE9_001516"
     CDS             7920..8222
                     /locus_tag="ACIZE9_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HGC6093380.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="ACIZE9_001517"
     CDS             8225..9388
                     /locus_tag="ACIZE9_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGC6093381.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="ACIZE9_001518"
     CDS             9414..12842
                     /locus_tag="ACIZE9_001518"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HGC6093382.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="ACIZE9_001519"
     CDS             12863..13987
                     /locus_tag="ACIZE9_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HGC6093383.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13968..14414
                     /locus_tag="ACIZE9_001520"
     CDS             13968..14414
                     /locus_tag="ACIZE9_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HGC6093384.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="ACIZE9_001521"
     CDS             14398..14736
                     /locus_tag="ACIZE9_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGC6093385.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="ACIZE9_001522"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="ACIZE9_001522"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGC6093386.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="ACIZE9_001523"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="ACIZE9_001523"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGC6093387.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="ACIZE9_001524"
     CDS             15893..16936
                     /locus_tag="ACIZE9_001524"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGC6093388.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="ACIZE9_001525"
     CDS             17095..17823
                     /locus_tag="ACIZE9_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGC6093389.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="ACIZE9_001526"
     CDS             17939..18184
                     /locus_tag="ACIZE9_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGC6093390.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="ACIZE9_001527"
     CDS             18181..18399
                     /locus_tag="ACIZE9_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HGC6093391.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="ACIZE9_001528"
     CDS             18535..19074
                     /locus_tag="ACIZE9_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HGC6093392.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="ACIZE9_001529"
     CDS             19067..21340
                     /locus_tag="ACIZE9_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGC6093393.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISAAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="ACIZE9_001530"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="ACIZE9_001530"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGC6093394.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /gene="rpsT"
                     /locus_tag="ACIZE9_001531"
     CDS             complement(22513..22767)
                     /gene="rpsT"
                     /locus_tag="ACIZE9_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGC6093395.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="ACIZE9_001532"
     CDS             complement(23167..23436)
                     /locus_tag="ACIZE9_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093396.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23698..23826)
                     /locus_tag="ACIZE9_001533"
     CDS             complement(23698..23826)
                     /locus_tag="ACIZE9_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093397.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            complement(23906..24361)
                     /locus_tag="ACIZE9_001534"
     CDS             complement(23906..24361)
                     /locus_tag="ACIZE9_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HGC6093398.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="ACIZE9_001535"
     CDS             complement(24499..26427)
                     /locus_tag="ACIZE9_001535"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC6093399.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26624..27457)
                     /locus_tag="ACIZE9_001536"
     CDS             complement(26624..27457)
                     /locus_tag="ACIZE9_001536"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGC6093400.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27649..28353)
                     /locus_tag="ACIZE9_001537"
     CDS             complement(27649..28353)
                     /locus_tag="ACIZE9_001537"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGC6093401.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28376..29002)
                     /locus_tag="ACIZE9_001538"
     CDS             complement(28376..29002)
                     /locus_tag="ACIZE9_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGC6093402.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29328..31703
                     /locus_tag="ACIZE9_001539"
     CDS             29328..31703
                     /locus_tag="ACIZE9_001539"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HGC6093403.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(31727..32218)
                     /locus_tag="ACIZE9_001540"
     CDS             complement(31727..32218)
                     /locus_tag="ACIZE9_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HGC6093404.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32405..33325
                     /locus_tag="ACIZE9_001541"
     CDS             32405..33325
                     /locus_tag="ACIZE9_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC6093405.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33479..33823
                     /locus_tag="ACIZE9_001542"
     CDS             33479..33823
                     /locus_tag="ACIZE9_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGC6093406.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34013..34513)
                     /locus_tag="ACIZE9_001543"
     CDS             complement(34013..34513)
                     /locus_tag="ACIZE9_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6093407.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35041..35124
                     /locus_tag="ACIZE9_001544"
     tRNA            35041..35124
                     /locus_tag="ACIZE9_001544"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35075..35077,aa:Leu,seq:cag)
BASE COUNT        11775 a         6169 c         7297 g        10197 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tgcagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttgtttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgctg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa
    26581 aaaccagaac atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc
    26641 aataaccaat caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt
    26701 ttttcttcaa atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga
    26761 atgttcctac aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat
    26821 atttgacgat cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa
    26881 actctgtagc gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag
    26941 aacgggatgt tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt
    27001 ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga
    27061 caataataaa ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga
    27121 aatttgcttc taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa
    27181 cgatcacttt aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag
    27241 aaaatgggtt taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga
    27301 taacgacatt gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg
    27361 ctaggatcaa atgaccagta ctactgatgg gcagccattc cgttattcct tcaataatac
    27421 cgagaatcac tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag
    27481 atacatctta tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga
    27541 aaaacttgag aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt
    27601 tcagactttg ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga
    27661 gtcgcgacta tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga
    27721 aaatcgaccg tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac
    27781 aggctgttta ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac
    27841 taaaacattt ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca
    27901 tacacggtct cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac
    27961 agcattagca atttgttcaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa
    28021 attcaataca cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc
    28081 gaaacaccat tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg
    28141 ttctcctaga ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa
    28201 tgaaaagtcg acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt
    28261 tgtgaggggt gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc
    28321 gtgtcgtacg atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac
    28381 gattgaaaaa aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg
    28441 gatagactgc aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt
    28501 gttctaaatt ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc
    28561 cagaaacgac aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag
    28621 ggacgacgcg aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg
    28681 caggcgagac aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa
    28741 tcggatcacc tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg
    28801 cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta
    28861 ccggctgttg gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt
    28921 caatgatcaa aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg
    28981 tttttaatct ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca
    29041 ttagtataac gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc
    29101 tgaattatca gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt
    29161 catagcattt taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc
    29221 ctatatccct gcctaatcag cagggtgttt ttttatgttt ggaaagagag ctctttttgc
    29281 taaactaggt tttttcaggt aatcttagag agaaagaggt ggtggaaatg atcaaacagt
    29341 caaaaatatc tgtgcggcac ttagtagaat ttattttgcg acgtggaagt atcgacaatc
    29401 gtaaaaaaag taaccatact gcattagaag gagcgagaat ccaccgcaag ctccaaaaag
    29461 atgcgggaga aaactatgaa aaagaagtct ttttaaaaac aacagttcaa ttagatgaat
    29521 attacctgat cgttgaaggc cgtgcagacg gtattttcaa aagagacggt atttattata
    29581 tagatgaaat caaaacctcc gaaccacgat ttgaagattt agaaccagaa caagtggaac
    29641 ttttctttca tcaagcaagg gtgtatgcct atatctatag tcaagaacat gatttacaag
    29701 aaataaatct gcaattgact tacttccaga cggcagaaga agtgatcacg agaaaggttg
    29761 aacatcagac aagagagcag ttagaaactt tttttaaaaa gctgactgaa gattataaag
    29821 aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa tgcctctttg atggctttga
    29881 aattccccca tgatgagtat aggaaaggtc agcgtgaact agcggtagct gcttataaaa
    29941 cgatccgtac gaaacagaaa ttgtttgtag aagcacctac cggaacagga aaaacaatct
    30001 ctacgttatt ccccgctttg aaagctgtag gggaagaaga gggagaaaag atcttttatc
    30061 taacggctaa aacaataact agacaagtag ctgaagatgc tatgacagca ttaaaagata
    30121 caggagctga agtaaaaagt gtcactttga cggcgaaaga caagatctgc tttttagatg
    30181 agacgacctg taatccagat cagtgcccat atgccaatgg ttattacaat cggattaatg
    30241 aaggtttatg ggatcttttg aatcatgaga atcagatcac tcgtgaagtc atcgaaactt
    30301 atgcaagaaa gcatacactt tgtcctttcg aactatcatt agatgtcagt atctggtgtg
    30361 acgtaatcat tggggattac aattatttat ttgatccaac tgtttattta agacgttttt
    30421 ttgaagatga aaaaaacgag gactatctgt ttttgattga cgaagcacat aatttggtga
    30481 atcgttcccg agagatgtat tcggcagaac tatcttatga aaaaacgaaa cgaagtaagg
    30541 aagctatacc aaaggaattc aaaaaacttc atcgccgttt caacaaacta ttaaaagaat
    30601 ttgattcgat ccgagaaata gcaaaagaag atcattggga ttatcatcat caaaaagcac
    30661 cggctgaatc tttagtaaag gcaggttatc aattaagcga aaaaattaaa gaatggctgg
    30721 cagaatttcc tgagcaccca tcacaagaac aattgcttcc ttattatttt gatttgcttc
    30781 attttttgaa ggtcagtgaa ttttatgatg atcactacga aacaacagtc gaaaaaacgt
    30841 atcgcgatct gatagtaaaa gagttttgta ttgatccaag cttgtttctt gagcagtcgt
    30901 tggataaagg aaaaagcagt attctttttt ctgctagttt ttcaccactc tcttattatc
    30961 aggaaacact ggggggacaa aaaagtctgg cttacaaact gccgagtcct ttcccagaag
    31021 gaaaccagca agttttcatc gcaaattacc tagagacgac ttatcgaaaa agggaacaca
    31081 gtctggcaaa attagtagag acgattcatg cttttgctga tggaaaggtc gggaattatt
    31141 tcgttttctt tccttcttat caatatttag atcttgcggt ggaagcattc agacagcaat
    31201 atcccgacag caatgtgcta atccaagaaa cggacatgaa tgaggaagaa cgcgaacgat
    31261 ttttaacaaa atttcaaaca aatcccgctg aaacattgat tggattttgc gtacttggcg
    31321 ggattttttc agaaggaatc gatttgagag gggaccgatt gatcggcagt atgatcgtag
    31381 gtgtaggttt gccgcagatg aatcatgagc aggaactgat caaatcatat tatgatgaga
    31441 aggaacacct tggatttgct tacgcttatc agcttcctgg aatgaacaaa gtcttgcaag
    31501 ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat cgttgtattg gcagatcaac
    31561 gattttctag tttttcttat cgacgtttat tcccacaaca ttggcaaaca gcaagagaag
    31621 tacgaagtgt tggggaattg gaagaaggaa tacagcgttt ttggttatca aaagaagcag
    31681 taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt ttttgattaa cgatagttag
    31741 tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa agcaatcaca gcttgtagat
    31801 catcacggtt cttacctgtc actctaatct gatcttcttg gatttgtgct tttactttca
    31861 gtttttcatt tttgatagct gtagtgattt tcttcgcgtt ttcacgatcg attccgttga
    31921 ccaaatcggc agtttgtcga gctttgccac ctagagcgtg ttctgattcg gaaaaatgga
    31981 tatttttgat tggcacattt cttttgatca gcttaccaaa taatacatct ttgatctgtt
    32041 cgattttgaa atcatcatcg ctcaatacaa ctagattgct gttctctaat ttgatttcta
    32101 ctgtagaatc cttgaagtca aagcgattgg acaattcttt tgttgtttgc tgaatcgcat
    32161 tttttacttc ttctgtattg acttctgata caatgtcgaa gctagcatct tttgccatag
    32221 gaaccctcct gatatacata taaatattta ccatacatct atcttatcat aggattaggg
    32281 cagattctta cctgtttgct aaaattcttc tcatttgagt tcgaagtatt ttattttaat
    32341 agataaactg ttattcttac atttggaata ccaaagtagg ggagaggtgc ttgtgagtaa
    32401 aattatgact gcgtatcata aaaatgaaag attaaagaaa atagtggtta ttttgataac
    32461 cggattgacc gctgcggtcg ctttaaatta ttttttgatt ccagccaatg tcttttctgc
    32521 agggatgaat gggatcgctc aaatcatttc ctcgctttta tatgaatggt ttcatatcaa
    32581 gatagacaca ggaacattta tttttctttt gaatatccct gtgtttgtat tagggtttct
    32641 caaagtagga aaacgagcaa cgatccttag ttttgtgaat gttgtatgtg tatcggtgat
    32701 gacgatgctg cttccagtcg gacagatcac tgataatatt ttgatgaatg ccctagtagg
    32761 cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa atgggcttta caactggtgg
    32821 gatggatatc atctctcttg tactttcaca aacaactgga aaaacagtcg gaaactacat
    32881 gctgattcta aatggtatca ttgtagtcat cgcaggcttc ttctttaact gggaaagtgc
    32941 cttgtatacg attatttcca tttatgcaat gactcaagta attgatgcca tccacacgag
    33001 tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca gaagaggtaa cagaagaact
    33061 agcaaaacgg atggtacgtg gaatgacatt actgccgtct gtcggtggct attcaaaaaa
    33121 acaagggaac atgatcatga tggtcatcac ccgctacgaa atgtatgatc ttgatcagat
    33181 cgttcatgaa atcgacgacg atgcatttat caatatttta ccaactcatt cagtatttgg
    33241 ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca actggcgtat tgccagaaat
    33301 aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt ttagaataaa tttaatctat
    33361 tacatctaat aagaacattt ttataaattt aaacgagaat cttacttcta aattctcatt
    33421 tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt gttaaggagt gtcgtacgat
    33481 gagcgaagca aaccaagaac ggtctggaca agaaatagaa ctaatcaaag aacgtattct
    33541 tgctgccttg gaaatggtga ttgatcctga attaggaatc gacatcgtca atttaggctt
    33601 gatttatgat atagaattca atcctgaaaa tggagaaaca gtcattaaga tgactctaac
    33661 aactatgggc tgtccattag cagatatttt aacagaatct atccatgacg cattaaaaga
    33721 agtgccagaa gtaacgaaag cagaagtcaa actagtctgg tatccagcat ggacgacaga
    33781 taagatgagc cgttatgcac ggattgcgtt ggggatacga tagaaatctt ggctgactag
    33841 ctatgagaag caaataggaa aaacaaaaaa gccttttatc ctttctagaa gaaaagagat
    33901 aaaaggtttc tttgtttata aaattttgtc tgctatatta taagttaatt aaataaatgt
    33961 gttctattga taaaggacat tcaaatccct ttccttttgg aatccttctt ttttacatca
    34021 gtttgatttt cgtatagtat tctttctcat cttcacgata aatcgcagcc ccattttttt
    34081 gttgtgcttt aagactgcca agattttttt tatttacaga caaaagtgcc tcatcaatgc
    34141 cgattttttt tgcctcttgt agtactaatg ctaatccttg tgtggcatat ccttttttac
    34201 gataattagg ggagatgccg taaccaatat ggccagcgcc gtttcttaat gtttcgttca
    34261 gtttatggcg caaattaaaa attcctacat actcatgttc atcactttct aaaataaaga
    34321 cggttgcggg aacgtaactc tcaggaagat cgattcctaa agacgttttt tcgcattttt
    34381 ttacataatc taaaaattca gcaaatgtat agccataagc attgttgata aatccactct
    34441 catttggtcc aaagctagtt tgtagctgat aagctttctt taaatctgct tcccatagtt
    34501 tgatcagttt catcgtattc acctctttaa gtaaccttat tcatttgttt tctactatag
    34561 cactattgtt gtaaatagcc atgcctattt ttatttattg tgtcatatcg tattaagaat
    34621 catcgaacaa tacaaatatg aattacaata aaaaaattat ttgaagttcg ttcattcgtt
    34681 acttatgatc tctagaagaa agaaaacgtg aattacttca gcgtctagaa ttccagaagg
    34741 atagtaatca acagaagaaa taatcaatat ccaaatgaaa gaagatagct gaatcgagaa
    34801 aaagaggaaa aaagaaatga agaaaaaaat aaaatagtta ctaatcccag agtcgttcgt
    34861 ttaacattga aatcgatcat atggataaaa cagatttttt caccaaccct caatagatga
    34921 tggagttgct cggatgaatt atttgtgtag atggcataag ggagggcgta cagaaatgaa
    34981 aaagaacaaa aatatgttct tgacaaaaaa cacatgtaat cctaaactaa aagatgtgat
    35041 gcggctatgg cggaattggc agacgcgcta gcttcaggcg ctagtgaggg tgacctcgtg
    35101 gaagttcgag tcttcttagc cgcataattt gtttttttat aaagagaagg tacacctgga
    35161 gcgatgagaa agaaaataac atattatcta aaagaatata ggaaaaattt taaacaacgg
    35221 aaccagattc aaataaatca aaaaaaattt gtgtgaaggt gggacagttt aaaacctaat
    35281 agattgattc aaatagtaga tttatagatt ctgatacaag aaatactggc aaacgatagt
    35341 taaggaataa agactaaact taaactcaaa aagaggtcat gcgaaagaat aaatcgcatg
    35401 acctcttact atattttgaa tgtgtttaaa cgttcaaa
//
LOCUS       DBBGSP010000026        34962 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000026 DBBGSP010000000
VERSION     DBBGSP010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.026"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="ACIZE9_001545"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="ACIZE9_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HGC6093408.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="ACIZE9_001546"
     CDS             complement(2020..2922)
                     /locus_tag="ACIZE9_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC6093409.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3611)
                     /locus_tag="ACIZE9_001547"
     CDS             complement(2919..3611)
                     /locus_tag="ACIZE9_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HGC6093410.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="ACIZE9_001548"
     CDS             complement(3654..4295)
                     /locus_tag="ACIZE9_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HGC6093411.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="ACIZE9_001549"
     CDS             complement(4333..4647)
                     /locus_tag="ACIZE9_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093412.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5264)
                     /gene="pyrE"
                     /locus_tag="ACIZE9_001550"
     CDS             complement(4635..5264)
                     /gene="pyrE"
                     /locus_tag="ACIZE9_001550"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGC6093413.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="ACIZE9_001551"
     CDS             complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="ACIZE9_001551"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGC6093414.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5984..6916)
                     /locus_tag="ACIZE9_001552"
     CDS             complement(5984..6916)
                     /locus_tag="ACIZE9_001552"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGC6093415.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="ACIZE9_001553"
     CDS             complement(6913..7689)
                     /locus_tag="ACIZE9_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGC6093416.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="ACIZE9_001554"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="ACIZE9_001554"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGC6093417.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /locus_tag="ACIZE9_001555"
     CDS             complement(10933..12009)
                     /locus_tag="ACIZE9_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGC6093418.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="ACIZE9_001556"
     CDS             complement(12014..13294)
                     /locus_tag="ACIZE9_001556"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGC6093419.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="ACIZE9_001557"
     CDS             complement(13313..14239)
                     /locus_tag="ACIZE9_001557"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGC6093420.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="ACIZE9_001558"
     CDS             complement(14252..15535)
                     /locus_tag="ACIZE9_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGC6093421.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="ACIZE9_001559"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="ACIZE9_001559"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGC6093422.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="ACIZE9_001560"
     CDS             complement(16323..17234)
                     /locus_tag="ACIZE9_001560"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGC6093423.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /gene="lspA"
                     /locus_tag="ACIZE9_001561"
     CDS             complement(17231..17695)
                     /gene="lspA"
                     /locus_tag="ACIZE9_001561"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGC6093424.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="ACIZE9_001562"
     CDS             complement(17700..18398)
                     /locus_tag="ACIZE9_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGC6093425.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="ACIZE9_001563"
     CDS             complement(18385..18771)
                     /locus_tag="ACIZE9_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093426.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="ACIZE9_001564"
     CDS             complement(18918..20588)
                     /locus_tag="ACIZE9_001564"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGC6093427.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="ACIZE9_001565"
     CDS             20771..21004
                     /locus_tag="ACIZE9_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC6093428.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="ACIZE9_001566"
     CDS             complement(21103..21534)
                     /locus_tag="ACIZE9_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HGC6093429.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="ACIZE9_001567"
     CDS             21613..22026
                     /locus_tag="ACIZE9_001567"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HGC6093430.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="ACIZE9_001568"
     CDS             complement(22064..23212)
                     /locus_tag="ACIZE9_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HGC6093431.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="ACIZE9_001569"
     CDS             complement(23334..23930)
                     /locus_tag="ACIZE9_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGC6093432.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="ACIZE9_001570"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="ACIZE9_001570"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGC6093433.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="ACIZE9_001571"
     CDS             27160..27591
                     /locus_tag="ACIZE9_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6093434.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="ACIZE9_001572"
     CDS             complement(27636..28985)
                     /locus_tag="ACIZE9_001572"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGC6093435.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="ACIZE9_001573"
     CDS             complement(29055..30218)
                     /locus_tag="ACIZE9_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGC6093436.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="ACIZE9_001574"
     CDS             30347..30670
                     /locus_tag="ACIZE9_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093437.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="ACIZE9_001575"
     CDS             complement(30853..32202)
                     /locus_tag="ACIZE9_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGC6093438.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="ACIZE9_001576"
     CDS             complement(32271..33224)
                     /locus_tag="ACIZE9_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HGC6093439.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="ACIZE9_001577"
     CDS             complement(33326..34516)
                     /locus_tag="ACIZE9_001577"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HGC6093440.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            complement(34716..>34962)
                     /locus_tag="ACIZE9_001578"
     CDS             complement(34716..>34962)
                     /locus_tag="ACIZE9_001578"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093441.1"
                     /translation="IRKNRTVTRLLSQSFFRIQQVKLLRNIQRVKLKIADKRRWKFYV
                     FLLVYAINKLNIQNTIDFNERASINGCVIFICPGRVK"
BASE COUNT         9952 a         7641 c         6120 g        11249 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaac ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg
    34621 attatgagaa ttatttaacc acatttttta tttacagtat ctttttactt tcaaatgact
    34681 tatatagtat gaacaattac cttttagata atgatctatt ttactctacc tgggcagata
    34741 aatataacac aaccattgat agaagccctt tcgttaaaat caattgtatt ctgaatattt
    34801 aatttattta ttgcatagac caataaaaat acataaaatt tccatcttcg tttatcagca
    34861 atttttaatt ttactctctg aatatttctt aaaagtttta cttgttgaat tcgaaaaaag
    34921 gactgtgaca aaagtcttgt cacagtccta ttcttccgaa ta
//
LOCUS       DBBGSP010000027        34661 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000027 DBBGSP010000000
VERSION     DBBGSP010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.027"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(313..2205)
                     /locus_tag="ACIZE9_001579"
     CDS             complement(313..2205)
                     /locus_tag="ACIZE9_001579"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093442.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2202..3929)
                     /locus_tag="ACIZE9_001580"
     CDS             complement(2202..3929)
                     /locus_tag="ACIZE9_001580"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093443.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3945..4595)
                     /locus_tag="ACIZE9_001581"
     CDS             complement(3945..4595)
                     /locus_tag="ACIZE9_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HGC6093444.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4799..5095
                     /locus_tag="ACIZE9_001582"
     CDS             4799..5095
                     /locus_tag="ACIZE9_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGC6093445.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5287..5907
                     /locus_tag="ACIZE9_001583"
     CDS             5287..5907
                     /locus_tag="ACIZE9_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGC6093446.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5999..7165)
                     /locus_tag="ACIZE9_001584"
     CDS             complement(5999..7165)
                     /locus_tag="ACIZE9_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC6093447.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7177..7530)
                     /locus_tag="ACIZE9_001585"
     CDS             complement(7177..7530)
                     /locus_tag="ACIZE9_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HGC6093448.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7658..8680
                     /locus_tag="ACIZE9_001586"
     CDS             7658..8680
                     /locus_tag="ACIZE9_001586"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGC6093449.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8699..8860
                     /locus_tag="ACIZE9_001587"
     CDS             8699..8860
                     /locus_tag="ACIZE9_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093450.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9119..9553)
                     /locus_tag="ACIZE9_001588"
     CDS             complement(9119..9553)
                     /locus_tag="ACIZE9_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093451.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9663..11522)
                     /locus_tag="ACIZE9_001589"
     CDS             complement(9663..11522)
                     /locus_tag="ACIZE9_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HGC6093452.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            11523..11663
                     /locus_tag="ACIZE9_001590"
     CDS             11523..11663
                     /locus_tag="ACIZE9_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HGC6093453.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(11640..12800)
                     /locus_tag="ACIZE9_001591"
     CDS             complement(11640..12800)
                     /locus_tag="ACIZE9_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGC6093454.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13107..14531)
                     /gene="araA"
                     /locus_tag="ACIZE9_001592"
     CDS             complement(13107..14531)
                     /gene="araA"
                     /locus_tag="ACIZE9_001592"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HGC6093455.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14547..15245)
                     /locus_tag="ACIZE9_001593"
     CDS             complement(14547..15245)
                     /locus_tag="ACIZE9_001593"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGC6093456.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15202..16863)
                     /locus_tag="ACIZE9_001594"
     CDS             complement(15202..16863)
                     /locus_tag="ACIZE9_001594"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HGC6093457.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17081..18481
                     /locus_tag="ACIZE9_001595"
     CDS             17081..18481
                     /locus_tag="ACIZE9_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HGC6093458.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18733..19812)
                     /locus_tag="ACIZE9_001596"
     CDS             complement(18733..19812)
                     /locus_tag="ACIZE9_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6093459.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19898..20857)
                     /locus_tag="ACIZE9_001597"
     CDS             complement(19898..20857)
                     /locus_tag="ACIZE9_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HGC6093460.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSKKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20869..22380)
                     /locus_tag="ACIZE9_001598"
     CDS             complement(20869..22380)
                     /locus_tag="ACIZE9_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HGC6093461.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22402..22965)
                     /locus_tag="ACIZE9_001599"
     CDS             complement(22402..22965)
                     /locus_tag="ACIZE9_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGC6093462.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(22971..23834)
                     /locus_tag="ACIZE9_001600"
     CDS             complement(22971..23834)
                     /locus_tag="ACIZE9_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6093463.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23848..24744)
                     /locus_tag="ACIZE9_001601"
     CDS             complement(23848..24744)
                     /locus_tag="ACIZE9_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6093464.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24919..26208)
                     /locus_tag="ACIZE9_001602"
     CDS             complement(24919..26208)
                     /locus_tag="ACIZE9_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6093465.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26180..27697)
                     /locus_tag="ACIZE9_001603"
     CDS             complement(26180..27697)
                     /locus_tag="ACIZE9_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HGC6093466.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27895..28785
                     /locus_tag="ACIZE9_001604"
     CDS             27895..28785
                     /locus_tag="ACIZE9_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HGC6093467.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28858..29682)
                     /gene="nadE"
                     /locus_tag="ACIZE9_001605"
     CDS             complement(28858..29682)
                     /gene="nadE"
                     /locus_tag="ACIZE9_001605"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGC6093468.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29694..31166)
                     /locus_tag="ACIZE9_001606"
     CDS             complement(29694..31166)
                     /locus_tag="ACIZE9_001606"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGC6093469.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31803..32165)
                     /locus_tag="ACIZE9_001607"
     CDS             complement(31803..32165)
                     /locus_tag="ACIZE9_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGC6093470.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32388..33140
                     /locus_tag="ACIZE9_001608"
     CDS             32388..33140
                     /locus_tag="ACIZE9_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC6093471.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33280..34203)
                     /locus_tag="ACIZE9_001609"
     CDS             complement(33280..34203)
                     /locus_tag="ACIZE9_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6093472.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34218..34490)
                     /locus_tag="ACIZE9_001610"
     CDS             complement(34218..34490)
                     /locus_tag="ACIZE9_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093473.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10230 a         7212 c         5979 g        11240 t
ORIGIN      
        1 caagaggttg tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc
       61 ttctcaggtt tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
      121 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa
      181 tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg
      241 tttattcgga aaaagggact gtgacacgac ttttgtcaca gcccctaaaa aaaataataa
      301 atttgtacta ttctatgaag cttcttcttc agaaaactga ctgttataaa gatctgcata
      361 gaatccgtct ttttccatca atgtatcgtg gtttcctgtt tctacgatcg aaccatgatt
      421 catcacaata atgttgtctg catcgcgtat tgtagacaag cggtgagcaa caacgaaact
      481 tgtccggttt tccaataggc ggttcatcgc tttttgaatc agtatttctg ttcgtgtatc
      541 tacactagat gttgcttcat caaggatcag gacatctgga tttgctaaga atgcccgcgc
      601 aattgtgatt agctgacgct gcccttgcga aatattgctt gcatcctcgt ttaatacagt
      661 gttatatcct tctggcaatt tacgaacaaa atcgtctacg tgagcagctt tagcagcctc
      721 aatgatttgt tcgtctgttg catcgtcgtt cccatatttg atattgtcat agatacttcc
      781 tgtaaacagc caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt catcacgtga
      841 aagatcacgg gtatctacac catcgtaacg aatactacct ccagaaacat cgtagaaccg
      901 ttcaagaagg ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa tagcgaccat
      961 ctcaccaggt ttgacatcca agttaaaatc agtcattagc aagttatctg gtgtgtagcc
     1021 gaattgaaca ttttcaaaac gaactttgta tggtgtatct ttttcttctg gaaggccaga
     1081 tttttcattg gacatctctt cttcatccaa cacttcaaat acccgttcgg ctgaagcaac
     1141 tgttgattgg atagtgttca tcaaacttgc aagttgagtg attggttgag agaactgtgt
     1201 tgtatattgc aagaacgctt gaacatcccc taatgtcatg ttcccatttg caacttttac
     1261 tccgcctagt acagcgacga acacatagcc tagattttta acgaaattca tcaacggcat
     1321 gatgattgcc gaaataaatt gagctttcca accagcggca tacagattct gattttcttt
     1381 ttcaaatact tcctggtctt tttcagtatg attgaatgtt ttaacaatgg tatgaccacc
     1441 atatgtttct tctacttggt tattcaataa acctaaactt ttttgctgat ctgcgaaaaa
     1501 cacttgtgat ttcggcgcta cgatcatcac gatgatcaag cttaaaggga tcatcaataa
     1561 cgcgactaac gtcaattgcc agctgattga aagcatcatc acgatgaccc caatcaatgt
     1621 gactgcacta gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga tgttatccat
     1681 atcattgatt gctcgagaca tgatatcccc atttgtatgt gtatcataat aggaaatcgg
     1741 tacacgattc attttggctt ccaaatcatg acgtaattca taaactgttc gttgggaaac
     1801 acgtgtcata ataaattgct gtaaaaagtt gaatacagca gaaatcaaat acatcacgat
     1861 tactgtcgca atgatctgcg cgattttatc aaagtctatc ggaaattttg ttacttgttg
     1921 gccttgttgc atctgttgag cgccagccat tacacctttg aatatttctg tggttgcttt
     1981 ccccaagacc tttggtgttt ggatttggaa gatcacggct gctattgcta gtacaaatac
     2041 agcgatgatc gcaaccatac gtttagacat atagccaaac aatcggcgta ccgttcccca
     2101 gaaattttta ggcttttcac cttttacacc gagatttctg ccaggtccac catgtcctgg
     2161 accgcctgct ggtccatgag agggacgtgt gtttgtttta ctcatgctaa gtcctcctct
     2221 cttagttgtg aatgaacgat ttcttgataa gtttcgtttg ttgctaatag ttcttcatgt
     2281 gttcctttgc caaccagttt tccttcatct agcacaagga tcatatctgc atccattact
     2341 gtacttactc gttgagcaac taaaacggtg atactttctt tcatattcgt tttcaatgct
     2401 tggcgaagat tggcatccgt tttgaaatcc aacgctgaga aggaatcatc aaacacatag
     2461 atatctgctg ttttgactaa tgcccgtgca attgccagac gctgtctttg tccaccagag
     2521 aagtttcctc ctccttgttc cacatggcta tctaagccat cttccatctc tgaaacaaaa
     2581 tctttagctt gtgcgatttc taatgctttc caaatcattt catctgttgc atccggctta
     2641 ccatactgca tattgtctcg gatcgttcca gagaacagaa ctgctttttg aggaacaaag
     2701 cccattaatt ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc atttatttgg
     2761 atcgaaccag attcgatgtc atataatcga gggatcaaat tgactaaggt cgttttacct
     2821 gaaccagtcc cccctatgat tgcgacgatc tcgcccgact tggcttggaa atcaatatct
     2881 tccaatgcaa gtttttctgc tccatgatat cgataattga catgattgaa ggccaatgtt
     2941 gcgttttttc cagcaaaaga aactgtttta ggattttcag ggtcatggat accgattttt
     3001 tcatccaaca cttcattaat acggtcagct gaagcttgtg cacgaggcac catgataaaa
     3061 atagcggaaa gcatcataaa gctgatcaag atctgcatcg cataagtcat aaatgcaatc
     3121 agattaccga cttccaaagt catatctgct atgtagtgtc caccaaacca agtgattgct
     3181 acgtttgtac cgctcatgat caatgtcatc attggcatca tcaatgcgac gatcgtatta
     3241 actttgattg ccgtatttgt ataatcttta ttcgctaaat caaaacgatt ttcttcaaag
     3301 cgtgtcttat cgaatgctcg aatcactctg acccctgtca atccttctcg aaataccagg
     3361 tttaaacggt cagttttctt ttgcatactt ttgaataatg gaacagcaaa gtacatgatt
     3421 ccgccgatca aaataatcat tactgggatg acaactaaga agatttttgt caactgatga
     3481 tctttttgat aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt gatcatcata
     3541 cgtaaaaaca tttgtgtaac catttggatt tgagtcacat cattggtcgt tcttgtgatc
     3601 aaagaggccg ttccatattt atcaaacgca tcttttgtca gactctctga ttttttatag
     3661 acatccgtac gcaattgctt acccagtttc tgtgattcac gagtagcaaa aaatgtattt
     3721 gcgatagcag ctaagatact gatcaaagaa aagccgatca tcacaaaacc tgtatgccaa
     3781 atataatcga catctccttg cgctacccct ttatcaataa tattggaggt aagtgtcggc
     3841 aaatataaat ctgccagtac ttggatcacc atgaaaactg cagctgcaat tgctgaagtc
     3901 aaggagatcc gttttacgat ttttagcatc tagttccctt ctttctattt atatactccg
     3961 tttttcagcc aagaaagttt caaattgaat tcactgattg cttgctctac tgagtaatct
     4021 tcagatgttg aaaataagcg atacgaatgc gcaattgttg taaatacagt attcatcact
     4081 aattggatca gtaattccaa ttcatgatca ttttttactt tcagcttcgt ccgatcgatc
     4141 aattcaagca actcttttgc atcttgtttg tgttctttat gtggatcgtg aggcgttttt
     4201 tggcgactcg tatgaggagc gacttttctt gaggcacggt aatccatgtt cataaacaag
     4261 ttacgataaa aagaagcatt ctcgccttcc aaaatctcat aaatcatttt agaaaaatag
     4321 gattcgaatc ctttgaatag atcaccatcg gattctttca ttagttgtaa catatcttta
     4381 gagctgtcac gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt atcttcaaaa
     4441 tactgataga aactgcctct agggatatcc gctaatttga cgatattagc aatcgaagct
     4501 tcttttaagg gtactctaga aaactcgatt ctcgcagcct cgattagtct tttttgtttt
     4561 tctttaggca aatggaaaaa tgtctgtgtc ggcatatgga ttctcctttc tttcaagatg
     4621 acacattgtc atatgacgct atgtcattat aacacctcct acctgttttg caagacattt
     4681 gcatagtttt tttcattatc atccgataca ttaaaaaagt gataagagga atccttccat
     4741 ttgaattaat gagagttgcc cattaaaata gccacatact aaacaaagga tgagataaat
     4801 ggcccaatca attagtgtcc aagacttcaa taaattgcct ctcgatgctg acagcatcgt
     4861 tttagataca agaaatacct tagattacac aaaaaaccac ttaagccact cgctttctat
     4921 ccccgctgct atcttgccaa gacaattaaa aaatctagat ccaaagaaac tttattatat
     4981 tctaagctat acaggcaggc gatcagaagc attagccgat caacttactg ctaatggttt
     5041 tcgtgctgtt tatatcattg gtgggatgga agctcttcag tcgagtgttg cttgaatatt
     5101 gcttgttaga ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct tttataccct
     5161 gtcttttttt agttatttat tcttcaacct tatcaatatg acttgatagc cttttctttt
     5221 tcgagtaaac tgattttgtt agtcatagtt ataacaatca tagcaataaa aggagaaggt
     5281 aagcatatgg catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc
     5341 acagttaagg cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa
     5401 gtgactgttt tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca
     5461 ggttgggaag cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa
     5521 aaaattgctc gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc
     5581 gcaaacgcct tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc
     5641 aatgtagctg gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt
     5701 aaaaaagcac tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct
     5761 caatatgtaa aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc
     5821 gaaggaatcg attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa
     5881 gctgctgctt taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag
     5941 gaaaaaatct tcaaagcagc atttgtgcct tggatatttt cccatctgtc tctttttgtt
     6001 attctttctg ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt
     6061 caaaaacatg agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac
     6121 cgatgattcc gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga
     6181 ttgctaactg attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta
     6241 ctgcaaaaac gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga
     6301 tagccggaat catcgctaaa aatgatccta agtaagggat caggtttaaa aaacccgcaa
     6361 taatccccaa cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga
     6421 ttgccacagc aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca
     6481 tttcactcag cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat
     6541 aaggtgctaa ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca
     6601 gagccactaa aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct
     6661 tagatatatc ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca
     6721 actgttcgcg aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa
     6781 tcgtatctac atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag
     6841 ggatgatcac tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga
     6901 tactgtaaag ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt
     6961 aatacaagat tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg
     7021 gtgcaaacaa atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa
     7081 caagtaaggc tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc
     7141 tgttcttctt attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc
     7201 caaaccaata gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc
     7261 ttctggacaa gcatcaaaaa tcaatgatac gtgagctact gtctttaaat tcccattggc
     7321 catcggaccg acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc
     7381 tttcaaagaa aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc
     7441 agctgttgct gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt
     7501 cccaatttct gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa
     7561 cagtataaca cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg
     7621 aaaactattt cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg
     7681 aacctatacg cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga
     7741 agaattagcc aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag
     7801 taaagctggc aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta
     7861 cgataaggat tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt
     7921 agcggttgat gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa
     7981 tgtctaccat atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga
     8041 agcgacaggt cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc
     8101 tgaccaacga ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc
     8161 cgaaaacggc aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg
     8221 ccatcttgtc tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac
     8281 agtccgcgtg ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc
     8341 gaccttgcca gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga
     8401 tggcaagttc ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt
     8461 tgaagatggt tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg
     8521 cgatttcgca ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa
     8581 tctgacatta tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt
     8641 ctatgtacca gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat
     8701 gaatcagcaa gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg
     8761 gaaaatcgaa gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca
     8821 gaactacttt gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg
     8881 aaaagaacat caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa
     8941 accgccgaga tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca
     9001 aggttgttgt tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa
     9061 aggtaatatt acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt
     9121 attttttcaa caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt
     9181 ggtcttgttt tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga
     9241 tactttggat catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt
     9301 tatgaatgcc cattgctttt gctggtggac gcaaagtact gactttcata agcattgccc
     9361 gatatttttt tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca
     9421 gttcacttgt ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc
     9481 cttctccgat tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa
     9541 tattcggtaa catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg
     9601 tttttatcct caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat
     9661 tcttattcgt gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca
     9721 tattggatca attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct
     9781 ttataccact gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct
     9841 aatgataaaa gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc
     9901 gctgcaaaat aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct
     9961 ttactgtcga acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg
    10021 atcgtatctg aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta
    10081 gaaagattct tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct
    10141 tgcagataat tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct
    10201 agattatcat actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac
    10261 tgaggtgttt tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa
    10321 atatatggat tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg
    10381 tcaaatccta atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg
    10441 atcgctgtcg tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc
    10501 atttttggta caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa
    10561 aaaccagtca atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc
    10621 atattgccac tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat
    10681 acttctacgc cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg
    10741 ttcggcgact cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca
    10801 gtgatttctt tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc
    10861 agattgtaca aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa
    10921 ggtatccata gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa
    10981 ttactgatat accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg
    11041 aatcgccttc cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt
    11101 cctgcggcag ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg
    11161 atttcagtga tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc
    11221 atataatttg caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg
    11281 acagatcctg ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag
    11341 aagaattttt ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca
    11401 ttttgacacc actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt
    11461 gctgctgttc cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc
    11521 aaatgcttgc tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta
    11581 cgaaattcga aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt
    11641 tatggccttt ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc
    11701 tgttgtttca cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag
    11761 acatgctcat tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc
    11821 agagaaaata tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac
    11881 ggcgcttgga aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac
    11941 aaaagataat cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga
    12001 gtcgatcccc ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct
    12061 ggaaaatcag tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat
    12121 ttatcaacaa tttcacttct tcctacattg ataagtacag catctttttt cattttttct
    12181 atattcgcct gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg
    12241 taatccgagg tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca
    12301 tcgcggatag aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt
    12361 gtgcctatcg ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca
    12421 taagcacttc ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc
    12481 atacgacttg cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct
    12541 tttactgcat tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct
    12601 ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt
    12661 gtaagccatt catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca
    12721 tctattattt tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca
    12781 atcaaatgaa cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc
    12841 aattagacaa ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt
    12901 aggctgagtg ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag
    12961 caaaatattg agggtgagat atcttgataa atggtgttcc gttagctgac attgataata
    13021 agactaaatt tcaaaaaagt tgaaaagcaa atttcgtcaa tctcttctta tttcttaaaa
    13081 ctaagtggct ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat
    13141 tttgcccacg tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg
    13201 ccacctgcct gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac
    13261 acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg
    13321 atcagcagtt tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct
    13381 ttcccatcaa atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca
    13441 acgattcttg gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag
    13501 attgcttctt ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc
    13561 cctcgagcca tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca
    13621 gcaaaaccgt atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt
    13681 ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg
    13741 cgaataccga tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca
    13801 taatcaccat agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct
    13861 tcgtctgata cgcgatcgat tacttgtaca agatctccga taccaaaata atcaacagtc
    13921 caaccaaatt gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg
    13981 ttgtcaccaa aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc
    14041 atccaatcag caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta
    14101 ttttgtttat ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga
    14161 tttaaattca tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta
    14221 gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt
    14281 gagaaagtat gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc
    14341 atgatttttg tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc
    14401 aattggccat tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc
    14461 agtgcttctt ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca
    14521 atattcaaca taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg
    14581 tgttttcgta aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg
    14641 agctgtctgg taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc
    14701 gcactttgcg catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga
    14761 attgctaagg gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca
    14821 tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca
    14881 taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag
    14941 atcgtcgccc atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat
    15001 aaaacagcat gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg
    15061 tccaagtcca caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt
    15121 ttgataacga aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg
    15181 acgagtccgt gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc
    15241 agcattttct atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat
    15301 cccctcacgg taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt
    15361 gatggtgatt ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt
    15421 cccatgtcga tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc
    15481 ggctgtgtcc atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac
    15541 ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga
    15601 tttcaatata tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat
    15661 gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt
    15721 tactcctgta atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt
    15781 atcgccttct agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat
    15841 acccaaagaa ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca
    15901 gttattcgta tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc
    15961 cggatggaca ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc
    16021 cgaaatgttc cctgtccctt tggctacact gttcgtagcg accataccgg ttcctgcatc
    16081 cccttctggc ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata
    16141 agcccctgat tcgcttaact tgccagcttc ttctcctgct actagaactt taggcaaaat
    16201 gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat
    16261 ttcttgatgg taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac
    16321 gcctagtact ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa
    16381 attaatttct ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact
    16441 ccatctctgc ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt
    16501 gattgtattt cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag
    16561 ataaccgtgc atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata
    16621 gatttcgaat acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc
    16681 ttctaatgaa taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc
    16741 ggcaatagga gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc
    16801 aatccctaaa gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt
    16861 cataatgatt taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc
    16921 ttacaatgat tattgtatac ttttgtacgt acatgtcaag cagttattta caagaataca
    16981 ataaaaaaca cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg
    17041 atcaaccgcc ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt
    17101 ttcctcatcg tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat
    17161 tggtgttatg accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc
    17221 ttctttgata ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt
    17281 atctggtctt ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat
    17341 ttttatggct ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat
    17401 tgcagcaagg attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta
    17461 tatgtctgaa atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat
    17521 gattgcttct ggcatgctcc tttcctatgt tgcagattat ttgctaaaag ggttgcctga
    17581 aacgatggct tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt
    17641 cggtgtttta gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga
    17701 ggcaaaaaga gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca
    17761 aatccagctg aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt
    17821 agaaaaatat cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca
    17881 aggagctaat gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc
    17941 agcgagcgat gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt
    18001 gctctttttg gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag
    18061 cgtgatggga ctttctttca tcctaccagc tgttttagga actgtactgg atgctcatac
    18121 aaattcgttg ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg
    18181 ggctccactg acatgggtaa tcgtaggcga aatattccca ctagctgtcc gcgggcgagc
    18241 atctggccta gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc
    18301 tgtgatgact gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt
    18361 tttaggggtt ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga
    18421 aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta
    18481 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag
    18541 tcacaaggaa caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac
    18601 cagttggtag gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc
    18661 gatgacaaaa gctctcacaa acattgcgac gagtaaccgt aggagcaata agaggcggta
    18721 aaaacccgtc tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc
    18781 atagagaata tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc
    18841 atcttgtccc aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg
    18901 gcttaaagaa gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt
    18961 ttctgtcaac ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc
    19021 taaagcttgt tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc
    19081 cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct
    19141 gataaaacct ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag
    19201 acgctgatgt ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc
    19261 taaacaaata taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat
    19321 gccttgttct ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt
    19381 aggctcaacg atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc
    19441 caattcgtga tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc
    19501 attttcgatt cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac
    19561 accgatcgtt tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata
    19621 tgtgcccgac cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg
    19681 ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt
    19741 tgtatttact tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg
    19801 atattttgcc atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg
    19861 caaggtttat tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt
    19921 caccaaattc tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat
    19981 taggattgtc taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa
    20041 tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat
    20101 tttttttaga agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa
    20161 gattcttgtg ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac
    20221 cagaatacgt aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg
    20281 aaaaaccccg tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta
    20341 acgtccaagg attatccatt tcggatagat aaagattaga attcccagta atttcaggat
    20401 cttgttgggc ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac
    20461 tgaaagtttc ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat
    20521 ctatatgctg attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt
    20581 tatgattgct tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg
    20641 cccagatcaa ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag
    20701 catgttctaa ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa
    20761 ccgatcctgt aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt
    20821 gccgaacgat aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt
    20881 tattctaatt acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc
    20941 tattgaaaaa tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc
    21001 caacagatcg ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg
    21061 ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt
    21121 gccgttatct acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata
    21181 aacagggcaa atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg
    21241 catcacataa taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg
    21301 tattgtgttt actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat
    21361 agccagccct aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat
    21421 gggactaccg acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc
    21481 atcaaacgct agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt
    21541 agcaacgatt tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt
    21601 atcatcacgc tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata
    21661 gttatgcaaa gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca
    21721 ttcagggtac gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc
    21781 atccactaac ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact
    21841 cttagccccc acttgccatg gaccgtctag ctcattccct aaacaccata atttaacgcc
    21901 aaaaggcttt ttttgcccat tttttattct taaatcactc cagaaggttc cttttggaaa
    21961 attacaatat tctactaaat tttttgcttc atcaattcct tttgttccta aattcaccgt
    22021 gaatatcggt ttcgcttgta catgactgat ccatttaaaa aattcgtgga gtccaaaaga
    22081 atttggttct atacctcgcc atgctaaatc aatttttttt ggtcgttgtt ctttcctacc
    22141 tacagtatcc acccaatcat aaccagatgt aaagtttcct ccaggatagc gaatgacacc
    22201 taattctaat tcctttacat aagagaggac atcttgtcta aacccgtcac catcagctgt
    22261 ttcatggccc ggttcataaa tccctgtata gacgacactt cccatatgct caacaaatga
    22321 gccaaacagc cgagaactga tctctcctac cgtaaaatcc tctctgattt ttactttcac
    22381 ttcttcgtcc aacagctttc cctacctttc atttcctata gtcaagataa tagatacaag
    22441 tttccatacg ccaccagcaa agataaaaat aaaaggaggg aaaagaaata tgagcagtac
    22501 aaatcctaat aacaatacgc aacaaagaat atttctcaaa aaatcaaaaa atactttcca
    22561 tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg ttttcagaaa tcacatatat
    22621 ccaggataaa agaaacatgg aataaataag taaaactaca tatccactaa ttgaaagtac
    22681 gattgtctgt tcttctaata attgattaac aagaaaataa ataatgatcg ttaacagact
    22741 aaggaacaag ttcttaccaa aatgttgctt tattccttga aagaaaaaat aaatgatatt
    22801 tcctgatccc tcacctttcc attgcgccat tacataaaaa acagcacatg tagcaggcac
    22861 gatagtaata acaggcaaac acacgattac ccagagaata cctaataaga tgtaatcaga
    22921 aaccacaatc aactgtccat aaagtttagt ctcaactatt ttcatcttcc tcactctttc
    22981 attccagaca tagctgttcc ttgaacaaaa tatttctgtg caaaaatata aaccactagt
    23041 aatggcagca ttgaaataac cgttccagcc attacaggtc cataaaaaga aatgttctgc
    23101 cctgtaaata aagctaaccc tgctggtaaa gttctcattt ttgaactact tgtcaatatc
    23161 aatggataaa gcaagtcatt ccaactattc atcagcgtga aaatccctaa tgataaaaga
    23221 gtaggtttgc tcaatggcaa catgattttc aaaaaaatat taaactcact taatccatca
    23281 atgcgtgctg cctcttccaa agaatctggt aaagtaataa aaaaggaacg catcatgaag
    23341 ataccaaatg cagttgtcat acgaggaatg atcaaacctg cataagtatc aagcatgcca
    23401 agcaaattga cttcaataaa tagaggaatc atgaagactt ggaatgggat catcattgtc
    23461 agcaaaacga aatagaacaa aactgatttt cctttgaaac gcatacgagc aaatgcatac
    23521 cccgcaagag aatcaaagaa tacagaagtg atcactgtcc ctccagcaaa aatcactgta
    23581 tttttgatgt aatctaataa agggatcgtt gtccaaacct taatatagtt atctagggta
    23641 tagctatctg caaatattct aggcggaaat gagataatgt ctttttcgtg tttaaaagaa
    23701 gaaataatca gccacaaaaa aggaaacgca ataaccaaca atataactag catactaatc
    23761 gttcgaatga tttttttacc actaactgct tttcgactat tcacagtaac tgtaatcgag
    23821 ctttctggtg ccatacaggt ttccctccta tttcatttgt ttttctttcc gtgacatgta
    23881 cacattagtg gagatagcta tagttgcaac aatgataaac aaaaccgaag acagtgctga
    23941 tgcatagccc aattcataag gtgctgtaaa tcctcgactg taaatatatt gaacagctgt
    24001 ttctgtctta aattgtgggc caccagcggt tgcaacatat acttggtcaa acacttgcat
    24061 cgaaccaatc agattcgtta aaatacaaaa acctaaggag ggaacgatct gaggtagcgt
    24121 aatgttaaaa aactgctgtc gatttgttgc accatccatt tgagcagatt catacaaaga
    24181 gggagagatt ccctgaatag cagtcaagag aatcgtcata gtaacaccaa aattcttcca
    24241 aacagtcatg atggctaccg tcggcatagc aagggttgga tcgcgaaaaa attgagggat
    24301 cggcaagccg acttgtgaaa acaagtaagg aatcgcccct acattcggat caagcaacat
    24361 agaaaaaata atcgcaattg acgtcaatga acaaataact ggaatgtaaa atgtcgaacg
    24421 acaaaaacga ttgaatctgg tatttttaga taatgctact gctgctaata aaccaacgat
    24481 aatttgtgtt ggcgtttcga gtacggtgaa atataaagaa tgaatcaacg aattaactgc
    24541 tcgttcatca ctaaatatac gtgtgaaatt ttcaaaactt acaaaatttc ttgatgtaaa
    24601 gaaaatattc aaatctgtaa aactaatagc aaatgttcct aaaagcggta tgacagtaaa
    24661 taataataaa actaaaaaag atggagttaa aaacaaatac gcagcacgat caggacgatt
    24721 ccaatatttg gtgaatccgt tcatatagtc cacctcatct ttcattttga taaaatatac
    24781 aatcttggtt taaacgaatc tgaataagat atccgaacaa tcgctgtgat ttttgcaata
    24841 acacctatct gcaaatacta ggtcgatcat tcagatatct gtatcttgcc aacagtctat
    24901 cctgtataaa gttctgtact atttttgcag taattgattg atggcatcat ctgcatcgtt
    24961 catgagtgtc tcaggatctt ctcctgctaa taatttttca atcagtggat tgatgatatc
    25021 gttattgatc gcagagattt gggtaaaacc tggtaaatat ggctctgcat agtccatttg
    25081 tttcgataat tcagatacaa taggatcatt ttttacttct tcatcttttg ctactgaatc
    25141 caagtaggca ggaaaaccat tttcgatact ccatttttta ccaatttcag ttgtattcca
    25201 atatttcaaa aactcataga cagcttcttt tttattatta tctgtacttg ccggaatggc
    25261 atatcctacg ccatctaaaa tagctgtttt tttgtctgaa tcactccctt gtggtaaggt
    25321 agtcacatta taatcaatct cgtttgcttt caatccgtta tttaaccatg gcccattgat
    25381 ttcaatggct agttgaccag cattcattaa attgtccatt tcggcgccag aaatcgattc
    25441 tggaccagtc ttgtctacat ggatcatttt ttggatcgct tttaacgttt taaggttctc
    25501 aggagacgca aattcagact tagtataatc atcgttcact aatttaccgc catttgctaa
    25561 catccagtta tataacggtg cagttccatc cttattgaag acaaaacctg atacattttt
    25621 actactatca gttaattttg gtgccatttc tgtcaattct tcccaagtag taggtggttg
    25681 ttcagtatct aatccagctt gtttaaacaa atcattattc caatacatat acatgccttg
    25741 tacctgcatg gggacaaaat actgtttacc ttctacttca cctaattcaa tagccgtttc
    25801 tttaaaatca gatttatcta ctccatcata ttcccagaaa tcgtctaatg gttgtaccgc
    25861 tccgttttct acatactgtg caaaatctgg ataatttaat gcaataaagt caggtgcttt
    25921 tttagaagaa atcgctgtag gaagtttttc attcaaattg gcccaagtca tgatatccat
    25981 ttcaattttg atgtttttat catttgtttt attaaattca ttaacgattt cttgcaatat
    26041 ttcaccatca gatgcagtaa acccattcca aaaagtcaaa gtcacttctt tatcagaatc
    26101 agattctgct gaacttccgc caccgcaagc tcctaaaata cctgttgcag ctaccaacaa
    26161 agagccaatt aaccattttt tacctttcat tttttgttcc tccttcatct gataaacgac
    26221 atctgaccac attccaagat agcggtttca ataaacaatt gattttccca tcttcagctt
    26281 ttacatttgt tgaatgactt ggttttactt gttcactttt aggaagatta gttgcttttg
    26341 tatcaaatcc actcatttca gaaaaatcaa tcactccctc taatgataat tcagacaagt
    26401 gaacagttag attcatttct tcttctccac ggttaactgc aaatatgaca agttctttgt
    26461 catttattac ggctatactt tctaaatacg gcacttcttc aaaatcttcc gtcgcatagt
    26521 ttgctgaacg aatttgtggg cttaacacct ctccttgtcc atacacagca gcttgcataa
    26581 atggataata gatcgtctgt ctccaagctt ctccgtttgt ttctgtcctg attggtgcaa
    26641 taacatttac caattgagca agacaagcaa tctttactct atctgcatgt ttcaataaag
    26701 tgattaatag acagcctaat agtaatgcat cttcaaaatt atagttatct tctagtaaag
    26761 gaggagcaat ctgccaaggc gctgcttgct catcttgttc cgctgaatga taccaaatat
    26821 tccattcatc aaaggacagg ttgatctgct tcttactatg tttcttcgcc ttgactgtat
    26881 cgcacatcgc tgtcacttca gaaatgaacc gatccatgtc taaggaacgt gcaagataat
    26941 gagaaagatc atttttttgg ttgccataat attgatgcag agacaaataa tctatttgat
    27001 cgtacgcttg atcaagaact gttaactccc aatcaccaaa tgtaggcatt tgccgattcg
    27061 aacttccgca taaaaccacc tcaattgaat catctacgag tttcatcgcc ttagccgttt
    27121 cctctgctaa ccgtccatat tcttccgctg ttttatgtcc aatctgccaa ggaccgtcca
    27181 tttcattccc taaacaccat gtcttaattc caaaagggct ctcttgacca ttcgaacgcc
    27241 ttaaatcact ccaataagtt cctttaggaa aattacaata ttcgactaaa ttacgagctg
    27301 catctactcc acgagtaccc agattgacag ccatattgat ttcggccccc acatgctgac
    27361 accagttata aaattcatga atcccaactt cattcgtttc aattgtccgc caagctaaat
    27421 ccaaccttct aggtctattt gctatgggcc caatactgtc ttcccaacga aatcctgaca
    27481 caaaatttcc accaggatat ctaatcatgg gaatgttcaa ttcttttacc aagtgaatga
    27541 cgtcttggcg aaatccactt ttattagctg atggatgatc tggctgataa atcccttcat
    27601 atactgctcg tcccatatgt tcaataaatg aactgtacaa ccgcggatca actttgccta
    27661 cacgcttgac actactaatc aacattgtgg cttccataac tgacctcctt taatttatac
    27721 atgaataata cacctcgttg aaagcgttgt caataatata aatgttaaac ttacttattt
    27781 tttatcgatt ttaattaacc aaaatattaa taatgattaa aacaaataat ttaatataac
    27841 ttttattaac aaatatgtta atatataaga aaaacctttt aagaggtgat atatatgcaa
    27901 ctacaaataa acgaagaatc cttaccggta tatgaagcat tagctagtaa aacaaggatc
    27961 aagatcatcc agctactttc caaaaaaaag atgaatgtca aagatttggc aaaagaactt
    28021 ggagtgagca gtgctatcac gacgatgcac gtgaaaaagc tagaggaagc aaacatcatc
    28081 aaaacagaaa aagtaggaca acaaaaaatt tcgagccttc gtgtcgataa aatcgatatc
    28141 agttttccag aaaaaatatt caatgctttt gatacgaaag aaacatcgat acctattggt
    28201 cactatacaa attatgcaat tgaaccaaca tgcggtttag ctacgatcca tgattttatc
    28261 gggaaagtgg atgaaccacg ctattttatg gatcctcgaa ggatggatgc ccgcattctc
    28321 tggtttacca gcggatttgt cgagtatcag gcacctaatt ttttaaatac agaggataca
    28381 ttggagatgt tggaagtttc tgtggaaatt tcttctgaat ttcctttttc aaatgacaat
    28441 tggccttcag atatcacttt cagcctaaat ggtgtggagc taggaacatg gacgagccct
    28501 ggagattttg ctgatatccg cggtaaatat acgcctgatt ggtatccaga taatcttaat
    28561 caatacggct tgctgaagac gatccgaatt accaaacact tgacgaatat gaatggagaa
    28621 cccttgtcaa acatcacgat caacgacatc cctaaagagc aagacacttg gcatttgcga
    28681 atcgaagtga aagacgatgc caaacatgtg gggggctgta ctttatttgg taaaggattc
    28741 ggtaattacg atcaggatat caaattaaaa gtttactaca gctgatattt ttcttttcta
    28801 ttttataaaa caaaaacagc caatccctat gaagggacgg ctgtttttgc tttattgtta
    28861 tttccagaaa tcatccaaaa cggaaattgg caaatgtcgt ttatgttgtg tcttgttcca
    28921 ccatgcttcg attttttctt gtgcttgagc gggaacttct tttccttcta gataatcatc
    28981 aatttcatta tatgtgacac ctagtgcgac ttcatctgca atcattggtt tcccatcttc
    29041 aagatctgca gtcggaattt ttgtgtataa tttttccggt gcattcaatg cttgaagcaa
    29101 ttgtttccct tgtcgtttgt ccaaacggaa taatggcaaa atgtcggctc caccatcacc
    29161 aaatttcgtg aagaatccag taatgttttc tgcagcatga tctgtcccta atacggctcc
    29221 tgctctttct ccagctacgg catattgcgt aatcatacgt tgacgtgctt tgatatttcc
    29281 tttgttaaaa tcgctgattc ccacacctgc ttcgcttaat acttgtactt gtgcatcaac
    29341 agctggtttg atatttactc gcagactaac atcgggctgg ataaagtcaa gagcagcttt
    29401 tgcatcttct tcatctgctt gttcaccata aggaagacga acagcgataa attgatagtt
    29461 ttcatctttt gtttcttcac gcatttcttc catcgttagt tgcgccaaac ggcctgctaa
    29521 agtagaatct tggccgccgc tgatacctag tacaaaagtt ttaagaaacg gatatttttt
    29581 caaatatgct ttcataaagt caatactttt acgtatttct tcttttggat caattgttgg
    29641 tttgacacct aattcattga taatttctgt ctgcaggctc atttattctc ctcctatgct
    29701 tctgtatgaa gttctgctac gctttttttc attcgttcca tgatagccat tttatggttc
    29761 cagcattcag tagacagatc gactgggtat ttttgcggat tcaagtctcg tttatactct
    29821 tcccatagtg aatctagatt ttcttttgta tattctttga tttcgtttag tgcaggtaat
    29881 tcgtaaactc tttttccttc gataaagata tcttgtaaaa ctgggcgagc tgtaaagtct
    29941 cgaacagttt tattgataaa cgtatgcact ggatggaaca tgaagatagc ttcttcttct
    30001 cgagggtctt catcccataa tgtcacgtag tctccttcag atttcccatc aaaatttcga
    30061 gtgatgcgcc acacttgttt tttccctgga gtagttactt tttctgcatt gcttgataac
    30121 ttgatcgtat ccatcatttt tccttcatca tcttcgatcg atactagctt gaatactgca
    30181 ccaagggctg gctgatcata ggctgtgatc aattttgtcc caacacccca tacatcaatt
    30241 ttagcttttt gcatctttaa attcaaaatc gttgcttcat ccaagtcatt cgaagcatag
    30301 atttttgctt ccgtaaatcc ggctgcatct aattgttccc gaacacgctt agatatatag
    30361 gccatatctc cactgtcgat gcgtacgcct tggaagttga ttttgtcacc taattctttc
    30421 gccacgcgaa tcgcacttgg cacacctgat ttcaacgtat cataagtgtc gactaagaac
    30481 acgcagtctt tatgggtttt agcgtaggcc ataaatgctt cataatcatt tccataagat
    30541 tggactaacg aatgagcatg ggtcccgcta gctggtatcc caaatatctt cccagcacgt
    30601 acattgcttg ttgcatctgc tccgccgata tatgccgctc tagttcccca gactgctgca
    30661 tccagttctt gtgcccgtct agttccaaat tccaatagtg gatcttctcc gatgacagat
    30721 ttgatacgag ctgcttttgt cgcgatcaac gtttggaaat tgaccatatt caacagtgct
    30781 gtttctacta attggcagtg cgctaaaggc ccttccactt ggattaatgg ttcatttgca
    30841 aaaactagtt ctccttcacg agcagaacga actgttgctt taaattcaaa attttgtaaa
    30901 tactccaaaa aaccttcagg atagacttct aatccacgca agtaagcaat atcggaatca
    30961 ttgaacgtca gattctctaa ataattgact aaccgttcca atcctgcaaa aaccgcgtat
    31021 ccgtggttaa aaggcatttc tcgaaagtaa cattcaaaaa cagcatgtaa atcagctcga
    31081 cctaattccc agtatgtctg catcatattg atttgatata gatccgtatg cagcgtcaaa
    31141 ctgtcgtctg ggtaagtatt attcatcttg tattactcct cttggcaagt tttcatttcc
    31201 tacccattat aacaaaaaaa attaatagga aaagaaatct tccatttttt ctgaaaaagc
    31261 acatgtttta cggatatttc ttgctaaaaa tgaactccat ctgctaaaac tatcctttct
    31321 tattggtatt taacctaaac gagaaagaat acttatttta ttcaatgtat ccgagacacg
    31381 aagaaattag cgttttctat ttttcttact tgataaaata agtagatttt cctactacaa
    31441 tcgtagccgt taagataccg atgattgaac aaatataacc aaatgtctct acaacataat
    31501 caatggcaaa agtttttgaa gcaataatac gtctttcctt ttttgcttct tatccccaaa
    31561 gaaacggata taacttatta tgtattgaat ttttttggaa aggcgaatta tgacaagata
    31621 taccttgcgt tgaaaaaact cgcggaaaaa atatcacacg tttttaaaaa gatacaaagt
    31681 aagaaagcag ctgtcaatag aatggaaaca aaaatggcga gacatcaatc agtctcgcct
    31741 tgttttttat tgtatacatt agatatggag caggttacca taaagatgat tattagtcgt
    31801 tattaaatag aatccttcgt atttttttgt tctatcacta caatatcttt atttggacgt
    31861 ttgaattgta ttccggcacg ttctagctcc tgtttcactc ctacatggac tttgacatct
    31921 tctcgtgtca tttttaaaac gtgatgaatc gcatagtcga tttcttgcct tgtgattttt
    31981 ttcttcgtat tgatcatcac gacttgcttt ttatcatatg tgtctaccaa tagcagttgt
    32041 gttcgatcta acgaaaataa tttgtaataa ttaatagccg tattcccaaa aaagaattcc
    32101 actactttag gataaaatgt cttaatattt aaattactat tcacaggtgt ttcgattagc
    32161 ttcatctcat tcctcttttc tatatagtcg atttagatcc aatcttaagt tatgttacca
    32221 tctttcctag cattaaggaa tcggttacaa ttgaaccttt aaagacaaaa ggatttacct
    32281 tttatcactt aatagtataa cataatttcg tgagaaaaaa atacaatttt ttcttgacca
    32341 tctcgttacg taaaggatta tgcttacatt tgtcaggagg aaaaataatg gagtacacaa
    32401 taaagaaaat gtcagagata tcaggagtca gtccgagaac cttgcgcttt tatgatgaga
    32461 ttggactgct aaaaccagct aggatcaatt cttcaggtta tcggatttat ggcaaaaaag
    32521 aagtcgatcg tctgcaacac atcttatttt atcgaacaat ggcattcaag ttggatgata
    32581 tccaagaggt cttagacaat ccatcttttg accaccagaa agctttaatc aagcatcagc
    32641 aaatgttgct ggaaaaacgg gcacaaatcg ataccctctt gacaactgtc caacagacac
    32701 ttgatatgta cgaaggagga agaaaaatga gtgacaaaga aaaatttgaa gggtttaaac
    32761 aacaaaagtt gaaagaaaat gaagaatcct atggacaaga gattcgacaa aaatacggaa
    32821 aaaaaaaggt tacagcatcc aatgaaaaat ggatgaatat ggataaagaa acgtatgaag
    32881 aaatgcaaac tgttgaaaag cagatgttat ttgatctcac tctttactta aaagaaccag
    32941 aagatgaaag cttagcagac cgtatcttcc aagctcataa gaagtggttc tcttacagct
    33001 ggcctgaata tcagccaaaa gcgcataaag gactaggaat gatgtacgaa gccgatgaac
    33061 ggttcactgc atattatgac gagcgaagtg gtcatggtgc agcaaaagct ttaaatgaaa
    33121 ttatccaaaa aaaggcgtaa tcttttacat gatccaacaa aaaagtacac gtaaaatgac
    33181 ctaataacaa aacagcagac acccaagtta gatttttatg ctaacttttg gtgtctgctc
    33241 cattctttca caagtttttt catcctactt taaatatatt catcgttgaa taaacgtata
    33301 aggtattttc actttatcct ttttttctgt aagaaacaat tgaaatgcca tttctccgca
    33361 agcttccaga tggtggtcga tggttgggaa accaagaagc tcgctgatca gcaaattatc
    33421 gcgtccaatc accactggtg tcttatcttg cagatagctt tgcaagatgc ctgctgcaac
    33481 catatccgaa tttgtaaaga caccatcaac tccaagctct ttaaaaaaga agcctgcttg
    33541 ttttcctttc tctgcatcta tacaatccca aaaaacaagt gattcatcaa aagatggaaa
    33601 aagttgatga catagctgca aagtgatttt tgagttataa cttagcctgc cacttcgccc
    33661 caacgtgatg cccaattgct ttataccttg ctgcttcaaa taagtaagac cttctgtaat
    33721 tgattgttct cgatcaataa agacacagct tgcctgtttt cccttgattt cttcacaaaa
    33781 aactagaggt ccatattttt gatatgccaa taaatcatct agtgtattgg cacgagacgt
    33841 aatgatcaat ccatcgaaag ctttagctgc aaattcttca agataccttc gctctttttc
    33901 tttatgatag cccgtcggta aaagtgtcac tttgtaatca taatcaaacg ctgcttcaat
    33961 gatcccactg atcaactgat caaaatacgg atgattggta taaggcagaa tcactccaat
    34021 gcttttcgtt tttccataac ttaactgtct ggcatttgca ttagggatat aatcgacttc
    34081 tttcatgacc gcaagtattt ctttcctttt ttcctcatct acatatggat gtccattgat
    34141 tacacgtgaa atagtagaaa ctgaataacc tgtgagcttt gcgatatctc gaatgtttgc
    34201 cactgctgct tcgccaccta tacaaaaaga ttttcttgta aatagtctac cacagctgga
    34261 ccgcattcaa aaaactgata catttttcct tcatgcgaaa aactgatccg ctgcccgccc
    34321 caatatatat cttttgtcaa attttcgatt tcattcattg gtatttcttt tactatattc
    34381 ctattcaacc cttgaaaact gtacaacgtt aatacggatc ccttgaactc gacaaacgca
    34441 taaaaataat tgttcgttgt gccatctgtt atctctacat aagtattcat tgcaagccct
    34501 ccttttgata ctttgagtat agtgtatgaa acgcgtctca tagcaaggag tttgttttgc
    34561 caaagaaaag ttttattcct ctttcattat taccaaagtc tcttatttta aattgaatac
    34621 attataatga tactgtaaat atatctttat tattagtgaa t
//
LOCUS       DBBGSP010000028        34651 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000028 DBBGSP010000000
VERSION     DBBGSP010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34651
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.028"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            581..1270
                     /locus_tag="ACIZE9_001611"
     CDS             581..1270
                     /locus_tag="ACIZE9_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC6093474.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1257..2465
                     /locus_tag="ACIZE9_001612"
     CDS             1257..2465
                     /locus_tag="ACIZE9_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGC6093475.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2759..4030
                     /gene="serS"
                     /locus_tag="ACIZE9_001613"
     CDS             2759..4030
                     /gene="serS"
                     /locus_tag="ACIZE9_001613"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGC6093476.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4579..6063)
                     /gene="guaB"
                     /locus_tag="ACIZE9_001614"
     CDS             complement(4579..6063)
                     /gene="guaB"
                     /locus_tag="ACIZE9_001614"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGC6093477.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6568..7263)
                     /locus_tag="ACIZE9_001615"
     CDS             complement(6568..7263)
                     /locus_tag="ACIZE9_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGC6093478.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7353..8453)
                     /gene="ychF"
                     /locus_tag="ACIZE9_001616"
     CDS             complement(7353..8453)
                     /gene="ychF"
                     /locus_tag="ACIZE9_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGC6093479.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8462..8653)
                     /locus_tag="ACIZE9_001617"
     CDS             complement(8462..8653)
                     /locus_tag="ACIZE9_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HGC6093480.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8674..9564)
                     /locus_tag="ACIZE9_001618"
     CDS             complement(8674..9564)
                     /locus_tag="ACIZE9_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGC6093481.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9551..10318)
                     /locus_tag="ACIZE9_001619"
     CDS             complement(9551..10318)
                     /locus_tag="ACIZE9_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HGC6093482.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10330..11043)
                     /gene="rsmG"
                     /locus_tag="ACIZE9_001620"
     CDS             complement(10330..11043)
                     /gene="rsmG"
                     /locus_tag="ACIZE9_001620"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGC6093483.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11275..13176)
                     /gene="mnmG"
                     /locus_tag="ACIZE9_001621"
     CDS             complement(11275..13176)
                     /gene="mnmG"
                     /locus_tag="ACIZE9_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGC6093484.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13193..14590)
                     /gene="mnmE"
                     /locus_tag="ACIZE9_001622"
     CDS             complement(13193..14590)
                     /gene="mnmE"
                     /locus_tag="ACIZE9_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGC6093485.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14889..15272
                     /locus_tag="ACIZE9_001623"
     CDS             14889..15272
                     /locus_tag="ACIZE9_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093486.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15440..16198)
                     /gene="jag"
                     /locus_tag="ACIZE9_001624"
     CDS             complement(15440..16198)
                     /gene="jag"
                     /locus_tag="ACIZE9_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGC6093487.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16216..17034)
                     /locus_tag="ACIZE9_001625"
     CDS             complement(16216..17034)
                     /locus_tag="ACIZE9_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HGC6093488.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17031..17387)
                     /gene="rnpA"
                     /locus_tag="ACIZE9_001626"
     CDS             complement(17031..17387)
                     /gene="rnpA"
                     /locus_tag="ACIZE9_001626"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGC6093489.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17505..17639)
                     /gene="rpmH"
                     /locus_tag="ACIZE9_001627"
     CDS             complement(17505..17639)
                     /gene="rpmH"
                     /locus_tag="ACIZE9_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGC6093490.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18162..19496
                     /gene="dnaA"
                     /locus_tag="ACIZE9_001628"
     CDS             18162..19496
                     /gene="dnaA"
                     /locus_tag="ACIZE9_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGC6093491.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19694..20824
                     /gene="dnaN"
                     /locus_tag="ACIZE9_001629"
     CDS             19694..20824
                     /gene="dnaN"
                     /locus_tag="ACIZE9_001629"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGC6093492.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21053..21295
                     /gene="yaaA"
                     /locus_tag="ACIZE9_001630"
     CDS             21053..21295
                     /gene="yaaA"
                     /locus_tag="ACIZE9_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGC6093493.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21282..22406
                     /gene="recF"
                     /locus_tag="ACIZE9_001631"
     CDS             21282..22406
                     /gene="recF"
                     /locus_tag="ACIZE9_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGC6093494.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22403..24349
                     /gene="gyrB"
                     /locus_tag="ACIZE9_001632"
     CDS             22403..24349
                     /gene="gyrB"
                     /locus_tag="ACIZE9_001632"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGC6093495.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24369..26840
                     /gene="gyrA"
                     /locus_tag="ACIZE9_001633"
     CDS             24369..26840
                     /gene="gyrA"
                     /locus_tag="ACIZE9_001633"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGC6093496.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27076..27375
                     /gene="rpsF"
                     /locus_tag="ACIZE9_001634"
     CDS             27076..27375
                     /gene="rpsF"
                     /locus_tag="ACIZE9_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGC6093497.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27425..27937
                     /gene="ssb"
                     /locus_tag="ACIZE9_001635"
     CDS             27425..27937
                     /gene="ssb"
                     /locus_tag="ACIZE9_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGC6093498.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27963..28199
                     /gene="rpsR"
                     /locus_tag="ACIZE9_001636"
     CDS             27963..28199
                     /gene="rpsR"
                     /locus_tag="ACIZE9_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGC6093499.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28342..30315
                     /locus_tag="ACIZE9_001637"
     CDS             28342..30315
                     /locus_tag="ACIZE9_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGC6093500.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30321..30773
                     /gene="rplI"
                     /locus_tag="ACIZE9_001638"
     CDS             30321..30773
                     /gene="rplI"
                     /locus_tag="ACIZE9_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGC6093501.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31047..32414
                     /gene="dnaB"
                     /locus_tag="ACIZE9_001639"
     CDS             31047..32414
                     /gene="dnaB"
                     /locus_tag="ACIZE9_001639"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGC6093502.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33194..34486
                     /locus_tag="ACIZE9_001640"
     CDS             33194..34486
                     /locus_tag="ACIZE9_001640"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGC6093503.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10563 a         6733 c         6850 g        10505 t
ORIGIN      
        1 ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac aagtaattgt
       61 caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc aactcattta
      121 tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc gatagaatca
      181 agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat ttccaacatg
      241 tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac aaataataat
      301 atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca tttctagctt
      361 acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc gagagacgta
      421 aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc aactagatgt
      481 ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg cttttttttg
      541 ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt tgattgctga
      601 cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg ggtatgaagc
      661 agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc ctgatattga
      721 attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag tgaaagagct
      781 acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg atatggataa
      841 gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta atccgttaga
      901 agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg ccccagatca
      961 gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg aagttaaaac
     1021 aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct acttgcttgc
     1081 tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt ggaaacaaga
     1141 aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag ataagattga
     1201 agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct ataaaattga
     1261 cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact tcaaaagaaa
     1321 tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta ttaaatgttt
     1381 ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg aatgcgattt
     1441 gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg aacggccgga
     1501 attttattat tccctttttc tttctattag atattggtgt tttgtattgg cgcttgattc
     1561 gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac atcgcaaacg
     1621 gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga gtggtaacaa
     1681 gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt aaaatcgaaa
     1741 aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca ctcacgtcca
     1801 tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa gatcttttaa
     1861 agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg gacgacttat
     1921 ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc tttgacatga
     1981 tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa aaaaatatcc
     2041 aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc gaaaaacttg
     2101 tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga gcaacgaaga
     2161 tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa aataacggag
     2221 caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt gtagaagaat
     2281 ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa agcattgtgg
     2341 ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct ttcatcatgc
     2401 accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt attgacgaaa
     2461 gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca cagaacccag
     2521 tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag gataatttgg
     2581 aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa cagccgttat
     2641 gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc agactgattc
     2701 gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag gaaatcatat
     2761 gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat tgatgactcg
     2821 gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc gtcgtaagct
     2881 actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg agatcgccca
     2941 attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag aagtcggtgg
     3001 caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga aacaaattgc
     3061 aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg aagaggacaa
     3121 tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa aaccacactg
     3181 ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag tagccggtag
     3241 ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct acaacttcat
     3301 gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt atatcgtcaa
     3361 cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg ttttccaatt
     3421 ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta actattataa
     3481 tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa gccctgcttt
     3541 tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc ttcaccaatt
     3601 caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag aattggaaaa
     3661 aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc gtgtgatggc
     3721 cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag aagtatggat
     3781 acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag atttccaagc
     3841 acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata ctcatactct
     3901 gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa actaccaaaa
     3961 tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga atctgaaagt
     4021 tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa aaattttgtg
     4081 aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact ggcttttgaa
     4141 caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga gaaaaaaatg
     4201 gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc agctgattga
     4261 acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca aggacaaatt
     4321 caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg tggcaaggga
     4381 acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa ataagaagaa
     4441 attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga aggagttgct
     4501 tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt tacttttgtc
     4561 ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt ttgtgatttg
     4621 tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa attgcgcttc
     4681 atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac gcaaaccgcc
     4741 gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac cttcgattcc
     4801 ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt cttttgaacc
     4861 tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac gtccttggaa
     4921 gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta gcatcactgc
     4981 atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc ctccgtctgc
     5041 aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag ctgtgagctg
     5101 aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc cgataccaac
     5161 ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg tcgcaacgtt
     5221 tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt ttcggatcac
     5281 acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg cttctaataa
     5341 agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta caagcaatcg
     5401 accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt ctttgatcgt
     5461 gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga ttttatgttt
     5521 ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca ctaagttgtc
     5581 ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca tgtcgcggtt
     5641 tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca caccactgat
     5701 acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg ttaagaagaa
     5761 cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat ccgcttgctg
     5821 gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca tagcaatggc
     5881 catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat tcaacttaat
     5941 atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac tttctgctgg
     6001 tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt cccagttgga
     6061 catttttagt accactcctc taatttagtt tatctattaa aataattgat tttttcattt
     6121 aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat ataaagcgtt
     6181 tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag taataagaac
     6241 agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac cgcagatgca
     6301 aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt cgagtagtaa
     6361 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta ataccgagaa
     6421 actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt tgtcacagtc
     6481 ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc ctagatatct
     6541 agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac ttccaataat
     6601 cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga taatgataac
     6661 tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg cagaaaacag
     6721 tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca ttcctggttt
     6781 cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca tcatataaaa
     6841 gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag ctggcgttgt
     6901 tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa gcaacagcaa
     6961 cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg ctggcttatt
     7021 gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg ttcttccgcc
     7081 tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt tttcttcttc
     7141 agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt gatttctttt
     7201 ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt gttctggttc
     7261 cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca aaagacattc
     7321 taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa taacattacg
     7381 tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc ttcttttgct
     7441 gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc acggataaat
     7501 ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat tccttttttg
     7561 aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa gcctaacaaa
     7621 tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa agcttctaaa
     7681 aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg agcactgacc
     7741 acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac ataatgattc
     7801 gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat tggttttgtc
     7861 gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc gatcgttcgg
     7921 gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag ttctgccact
     7981 gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt gttgatagat
     8041 tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag tggatcaaca
     8101 cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg acaaatagcg
     8161 tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt acttgcgcct
     8221 tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt tttcggatgt
     8281 acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc tacgttgggg
     8341 tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat cgcattaaac
     8401 aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc cataaattta
     8461 ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca aaatctcgac
     8521 gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct gcgcccattc
     8581 gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca acgatatcgt
     8641 gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt gaatattcaa
     8701 gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga tcttaccttt
     8761 cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac gatcttcgct
     8821 ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct tttcttttcc
     8881 atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta aattttcagt
     8941 tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta acagcgtacg
     9001 ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat ccggtaaaga
     9061 aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac tagctacttc
     9121 tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt cttctaacgg
     9181 attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg cttcttcgtc
     9241 aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg ctcgaaaacg
     9301 tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga tgatgggttg
     9361 aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt cttcaaatgt
     9421 tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga caacggtatc
     9481 atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat cgattcctcg
     9541 gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct tggtagactt
     9601 cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta ggtgcttctg
     9661 ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag tatttacgta
     9721 cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc agtaagactc
     9781 cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta ttcagtaatt
     9841 ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc gaatcacttg
     9901 ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc aaaatataat
     9961 catactgact gcttacttct gctaaagatc cttttaatct tgattctctt gccatcattg
    10021 acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata ctcaaatttt
    10081 cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga acatcataga
    10141 tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt ccttgtgcat
    10201 ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct agattcaccg
    10261 tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt tgtgccatct
    10321 cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg ggtatttctt
    10381 tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga cattcggcaa
    10441 ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt gttttgcttc
    10501 tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt cttgtttagc
    10561 caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag cagtgacaag
    10621 gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt catgatataa
    10681 ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc gtttattcag
    10741 agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta tgctaggaaa
    10801 ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta cttcaaatgc
    10861 taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg taatagctgt
    10921 aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga attgattcat
    10981 ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt cttctggtat
    11041 cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc cctactttaa
    11101 cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg aaaagtaaga
    11161 aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga agagagaact
    11221 agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta cgtattacgc
    11281 tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga tacttaggtc
    11341 tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt ggattttctg
    11401 caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga tgttttctgg
    11461 aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt ttttgatgta
    11521 gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca attcttcatt
    11581 ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta aaaagtcgct
    11641 tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt cttggacttc
    11701 ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa ctgcttcttt
    11761 tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt gacccatttc
    11821 tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag cacgtgaagt
    11881 cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca tgacaccgat
    11941 gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca aagctgcatt
    12001 gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac catttgtttg
    12061 tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga gctggtgtgg
    12121 ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt tttctaatcc
    12181 agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag ataaaccttg
    12241 aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat gacgtggttt
    12301 gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc ctaccccttc
    12361 aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt ggtgagtcgt
    12421 ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac tatctggtgt
    12481 gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa cagaatagtc
    12541 gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga tagcaaagcc
    12601 aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg gacctgatga
    12661 atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg taataacaac
    12721 tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa caccatcttc
    12781 gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt tttcgatcgt
    12841 atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg ctcggacagc
    12901 tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga tattcttacc
    12961 catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg gtccgcctac
    13021 agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta ataatgtttt
    13081 tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg cgccaacaac
    13141 gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc ttttattttc
    13201 ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg tcgccgacaa
    13261 cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc acaggcattc
    13321 ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct aacaacgcga
    13381 tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg ctgaagaata
    13441 aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg gaaattgaaa
    13501 aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt gctggcaaat
    13561 ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat aattgttcat
    13621 cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct gcttctgcta
    13681 atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt tcccgaattc
    13741 cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct tcgattacat
    13801 ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac aaatggttta
    13861 acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac ccttcccgca
    13921 gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg atcatctgcg
    13981 ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct ggataatcaa
    14041 tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag cggatcaaag
    14101 cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct gtttttgccc
    14161 gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc aagaatgctc
    14221 gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat agctgcaaaa
    14281 tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct tcccgcgtaa
    14341 atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga ttgctcttgg
    14401 gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat cgtttgtttc
    14461 cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa cgaacgatac
    14521 tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat tctaaagtaa
    14581 tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc ccactccacc
    14641 ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga ttaaattctg
    14701 gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta gatgaagttg
    14761 agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct ttgcgttctt
    14821 tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta aaaaaaacgg
    14881 tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa tatgtgagcc
    14941 cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat gtcgttttat
    15001 ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt gtggaatgct
    15061 tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta acaacgaaga
    15121 ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac tgtcattttg
    15181 agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct tatggaacag
    15241 tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa gcggatcaaa
    15301 actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt catcgtatac
    15361 tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt caacgtgatt
    15421 tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact aaataacgat
    15481 aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat gcagcatgga
    15541 tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct gtccgtttta
    15601 ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt tcacggtaat
    15661 tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg aagacttgtg
    15721 ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg ccttgctttt
    15781 gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg acaagagctg
    15841 gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt aaagctgctt
    15901 catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg ttgactacct
    15961 cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct actgtttcag
    16021 aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga cccattccta
    16081 ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg gccaaaccca
    16141 aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa atcggcatta
    16201 gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct taagagcacg
    16261 ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt tgaaagggtt
    16321 gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt ataatgaaag
    16381 accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga aattcatgat
    16441 cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac ttgcaaaagt
    16501 aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta agttcaacca
    16561 taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata acgccatcaa
    16621 gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc cattttctgc
    16681 atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc ttgaactata
    16741 ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca tgctctttgt
    16801 ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata aaatgatccc
    16861 tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat aaacaatata
    16921 acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac cggataagac
    16981 gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct tcacttactc
    17041 ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt ggagcgaacc
    17101 tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc caactccgga
    17161 tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac ttcattgcgg
    17221 tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg aggctgtccc
    17281 ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc cgtatggaac
    17341 acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag ttttctttcc
    17401 ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc tttcatcatt
    17461 tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc tgaaagaact
    17521 tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt actcatacgt
    17581 ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt tcttttcata
    17641 tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt tgatagtata
    17701 acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa acttatccac
    17761 aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg gattatccac
    17821 agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta atccacaatc
    17881 aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt tttatccaca
    17941 gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta gtggtgtgga
    18001 aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt gtggataatt
    18061 gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa atgctaaatt
    18121 agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc ctcgatgctt
    18181 tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc tataatacat
    18241 ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt gaggttccta
    18301 gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt gaagtcggtt
    18361 atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa gcagagcaag
    18421 aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta aaaaaagcca
    18481 tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac cagatggctc
    18541 atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg ctcttctttt
    18601 atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat caaatgctgc
    18661 aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct aatgatttca
    18721 tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga aatgttgatt
    18781 tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa gaagagtttt
    18841 tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc agtgatcggt
    18901 tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca tgggggctgt
    18961 ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt aaaaaagcgg
    19021 cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga caaattgatt
    19081 ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct gcgatgaata
    19141 gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa tcaggaaaag
    19201 gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat tatcacatcc
    19261 aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct agacaaatcg
    19321 ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga gctgaattcg
    19381 gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag ctgatggatt
    19441 ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta aattaatttg
    19501 tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca aaagttatac
    19561 acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt ttccacagaa
    19621 tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa caaacattca
    19681 aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg aattgcaaac
    19741 tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg taaaaatcac
    19801 actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa ttgaaacttt
    19861 tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt ccattgtttt
    19921 acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat ttactttaga
    19981 agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta tcgtaaatgg
    20041 attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc agatgaaatt
    20101 acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct cacaacatga
    20161 gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt tattagctgt
    20221 agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag cggctgatca
    20281 ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat taacaaatga
    20341 agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa cagaaacgat
    20401 gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt tgattccttc
    20461 aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga tcgaacgggc
    20521 ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc gtccagatgc
    20581 ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct tgagttatac
    20641 agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga aagcagcgtt
    20701 gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc gtccatttac
    20761 attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg tacgtacaaa
    20821 ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa aaaataaaat
    20881 tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg tttaaatcac
    20941 cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt tttattgcga
    21001 aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg cattgaaaca
    21061 acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag aagtcacagt
    21121 tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt tagtcgatgg
    21181 cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg aagttccaga
    21241 agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg aataagctgt
    21301 atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag aacctcgtca
    21361 tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc tacgtattag
    21421 ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg actgacgatc
    21481 aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta gaaatcttat
    21541 tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag ttaagtactt
    21601 acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta gtaaaaggca
    21661 gcccgcagat caggcggaag tttttagata tggaattagg ccagatcaat ccaatctatc
    21721 tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac ttgaagcaat
    21781 tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa caactagcag
    21841 cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg gagttttggg
    21901 ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc gagtatctca
    21961 ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa tttctcgcac
    22021 ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt ggtcctcatc
    22081 gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga tcgcaaggac
    22141 agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt aaagaagaga
    22201 caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat gataatcgtc
    22261 aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca acaacgacac
    22321 ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt caacaaggga
    22381 aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac gcgctaaaga
    22441 gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta aacgacctgg
    22501 catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg aaattgtcga
    22561 taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga ttattgaaaa
    22621 agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata tccaggcaaa
    22681 aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag gaaaattcgg
    22741 cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg ttgtaaacgc
    22801 gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact atcaagaata
    22861 tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc gccatggaac
    22921 aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt ttgatttttc
    22981 aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc gtatatcgat
    23041 tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg gcgggatcaa
    23101 aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac ctgtatattt
    23161 ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag acggctacca
    23221 ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggtggaa cacatgaatc
    23281 aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac aaaagctgat
    23341 gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga cagctgttat
    23401 ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat tgggcaattc
    23461 cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat tcttgctgga
    23521 aaacccaagt gtgggccggc aaattgttga aaaaggatta ctagcttcca gagctcgtct
    23581 agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga ttagtaatct
    23641 gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat tgttcatcgt
    23701 cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt ttcaagccat
    23761 cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca agatcttggc
    23821 aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag aagattttga
    23881 tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg tcgacggcgc
    23941 gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta ttgttgaagc
    24001 tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga agaatattac
    24061 gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg cttcacttcc
    24121 tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg atgatcatca
    24181 actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca gtgtggacga
    24241 tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag aaccccgtcg
    24301 tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat catgaaggag
    24361 gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta accagcgaaa
    24421 tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca cttcctgatg
    24481 tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac gaattaggtg
    24541 taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc atgggtaaat
    24601 accatcctca tggagacatt gcgatctatg agtcaatggt acggatggca cagccattca
    24661 gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac ggtgacggtg
    24721 ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa atgctgcgtg
    24781 atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa aaagaaccag
    24841 ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg atcgccgtag
    24901 gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct atcgatttgc
    24961 tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct ggaccagatt
    25021 ttccaacagg tggtttggtt atggggaaat caggaatccg aagagcgtat gaaacaggta
    25081 agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat ggtaaagaac
    25141 ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc gaacggattt
    25201 ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac gaatcttccc
    25261 gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatcc gttatcttga
    25321 ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg ttggcgatcg
    25381 aaaaaggtgt gccgaaagtt ttgagcttga aacaaatcct tgaaaactat atcgaacatc
    25441 aacgcgaagt catcacacga cggacggtct ttgaaaaaga aaaagcagaa gcaagagcac
    25501 acatcttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt gcgattatcc
    25561 gcgggtctaa atcagatgac gaggcaaaag caacaatgat cgaacggttc gatttatccg
    25621 atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt ttggaacggg
    25681 aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta actgacattc
    25741 tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac ttgaatcaac
    25801 gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt ctggaagatg
    25861 aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt tacatcaaac
    25921 gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc caaggaatgg
    25981 gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat gatacattgt
    26041 tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt ccagaatacg
    26101 ggcgtacagc caaaggaatc ccaatcatca atttactagg tatcgattcg agtgaaagca
    26161 tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc ttctttacga
    26221 cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc cgaagtaatg
    26281 gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta ctgacagatg
    26341 gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc aaagaagaag
    26401 cagtccgcga tatgggacgt acagcttccg gggtcagagg gatacgcctg cgtgaggaag
    26461 attatgtcgt tggggcagcc ttaatgaagg aaaatcaaga agtattagtg atcacagaaa
    26521 aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc ggaggtaaag
    26581 ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg accactgttt
    26641 ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt ttcaacgtat
    26701 cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag atggaagctg
    26761 atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa acagttgaag
    26821 aacaaggatc agaagaataa ccatcaagac taagtgtgta agctagcaag aataaccgat
    26881 taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct taaaatattc
    26941 gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataattag agcttgtgag
    27001 tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg aaagtccaca
    27061 gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat tcgtccaaac
    27121 attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt gaaagataac
    27181 ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta tgaaatgaac
    27241 ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc agcaaatgct
    27301 gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca catgattgtt
    27361 aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag aggagatgac
    27421 tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag atttgcgtta
    27481 cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta attttacaaa
    27541 ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca aatcagcaga
    27601 aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac gtatccaaac
    27661 tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag tagctgacaa
    27721 cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg gcggattcca
    27781 aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc aaacatctca
    27841 atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg gctcaagttc
    27901 aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag gagggaaata
    27961 gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac attgctgcta
    28021 accatattga atatatcgat tataaagata tcgaattact aaaaagattt atttcagaac
    28081 gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa cgtaaaatta
    28141 ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc gaagactaat
    28201 aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct ttttttctgt
    28261 aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa aatcaaatta
    28321 gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc gaaacctctc
    28381 ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc atttcgtttt
    28441 gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg gttgaaaatg
    28501 aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac tgtagctgaa
    28561 accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta tcagccatca
    28621 agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca aagtggatta
    28681 acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa aaaccaagtc
    28741 tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt tgtttatttt
    28801 aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca gccggtgatt
    28861 ggtattttat ctattgataa ctatgcagat gccattgata aattagatga caaagagatt
    28921 tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga ataccatgtc
    28981 tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat cgatctgaaa
    29041 aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc tgaaaaacag
    29101 agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct cgatgaaatc
    29161 ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga ccaagttgtc
    29221 gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc tgctaagaat
    29281 gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg gatttttgat
    29341 gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc tttaggctct
    29401 gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat cgttatcaat
    29461 gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa gcatcctgaa
    29521 ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga agaggacctc
    29581 ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct atatgagcaa
    29641 tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc aagtaaacct
    29701 ctgctgactt atattgaatc ttcagcttct tcagcttcag agctagtttc tgagctgatc
    29761 caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt attgcttgca
    29821 gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac ttttgacgtt
    29881 gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt attgagctcg
    29941 gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta tgtgacttct
    30001 gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat agcagcaaaa
    30061 acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat tacaaagcgg
    30121 acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt ccaaatcatc
    30181 atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact ggaaaatacg
    30241 acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat gaatcaaata
    30301 tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa ggaaaaggta
    30361 aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta atcaaaaata
    30421 acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa aagaaagcac
    30481 aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa ttcttggaaa
    30541 aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt ttgtttggtt
    30601 cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc aaattagata
    30661 aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac gtacctgtta
    30721 agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa taacaaatct
    30781 tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac cgaaatttat
    30841 ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag attgatttcg
    30901 gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa aagagaacta
    30961 tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt gtaaaatgaa
    31021 gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga atcccaccgc
    31081 aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca gaaacgatca
    31141 ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat caaattattt
    31201 ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt actgtcaaag
    31261 accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat ctctcagact
    31321 tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc gttgaagaaa
    31381 aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa ggattcgagc
    31441 aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg gaggtttcgg
    31501 aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc acgattgaaa
    31561 atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact ggctatcaag
    31621 gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt gctgcacgtc
    31681 cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga acaaaaacag
    31741 atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta aatcggatgc
    31801 tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt tcggaagaag
    31861 aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt tttatcgatg
    31921 atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta gcgcaagaaa
    31981 aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt aacggtaaag
    32041 agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg gcgaaagagc
    32101 tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag cgacaagaca
    32161 aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat gcggacatcg
    32221 tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac gatgatggaa
    32281 acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga agcggtgcac
    32341 gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg ctttcgccaa
    32401 gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct ctcgtaagaa
    32461 gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat ctccaaaggg
    32521 attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc aatcagctga
    32581 cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg tttgtttctc
    32641 taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt gttctcctgc
    32701 caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt ttgaaattgc
    32761 tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg gtgttcaaaa
    32821 gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta tttttgtttg
    32881 gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca cggtgttcca
    32941 aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag caattttcgt
    33001 acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt ttaataacca
    33061 ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata aaaatcattc
    33121 gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa ataatataga
    33181 acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg atgaagggaa
    33241 aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt accaaggtgg
    33301 cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc atttgattcc
    33361 ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg tagtcaatcc
    33421 taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa caagtaattt
    33481 gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg accaattaca
    33541 agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg gacctgccta
    33601 tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata aagaaatttt
    33661 tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa aaatgtttga
    33721 ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg gacaacaaat
    33781 caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg caggcaaacg
    33841 cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa cttatccttt
    33901 tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg tagggccttc
    33961 aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg gtgatggacc
    34021 atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag gacgagaata
    34081 cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag ttatgcgcca
    34141 ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg tattaagtgg
    34201 attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa tctaccacta
    34261 tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat tgccaggctg
    34321 gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg cacgtaacta
    34381 tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg tcggacctga
    34441 tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat aaaaacgacg
    34501 actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg ataataataa
    34561 cttgaagagg tagtgaaaga gacgtttagc cttattgccg ataggctgtc tcttgaacac
    34621 tgtttattca gaataaggga ctgtgacaaa a
//
LOCUS       DBBGSP010000029        33674 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000029 DBBGSP010000000
VERSION     DBBGSP010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.029"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            214..498
                     /locus_tag="ACIZE9_001641"
     CDS             214..498
                     /locus_tag="ACIZE9_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HGC6093504.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(815..1198)
                     /locus_tag="ACIZE9_001642"
     CDS             complement(815..1198)
                     /locus_tag="ACIZE9_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HGC6093505.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(1200..1784)
                     /locus_tag="ACIZE9_001643"
     CDS             complement(1200..1784)
                     /locus_tag="ACIZE9_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HGC6093506.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="ACIZE9_001644"
     CDS             complement(1831..3306)
                     /locus_tag="ACIZE9_001644"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HGC6093507.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="ACIZE9_001645"
     CDS             3487..3798
                     /locus_tag="ACIZE9_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093508.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="ACIZE9_001646"
     CDS             complement(3913..6249)
                     /locus_tag="ACIZE9_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HGC6093509.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="ACIZE9_001647"
     CDS             6391..7059
                     /locus_tag="ACIZE9_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6093510.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="ACIZE9_001648"
     CDS             7062..8105
                     /locus_tag="ACIZE9_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6093511.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="ACIZE9_001649"
     CDS             complement(8342..9223)
                     /locus_tag="ACIZE9_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC6093512.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="ACIZE9_001650"
     CDS             9382..10110
                     /locus_tag="ACIZE9_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HGC6093513.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="ACIZE9_001651"
     CDS             10266..10583
                     /locus_tag="ACIZE9_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC6093514.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="ACIZE9_001652"
     CDS             10576..11184
                     /locus_tag="ACIZE9_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGC6093515.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11239..12030
                     /locus_tag="ACIZE9_001653"
     CDS             11239..12030
                     /locus_tag="ACIZE9_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HGC6093516.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            12168..12656
                     /locus_tag="ACIZE9_001654"
     CDS             12168..12656
                     /locus_tag="ACIZE9_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HGC6093517.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="ACIZE9_001655"
     CDS             12707..13579
                     /locus_tag="ACIZE9_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGC6093518.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13755..14117
                     /locus_tag="ACIZE9_001656"
     CDS             13755..14117
                     /locus_tag="ACIZE9_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HGC6093519.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14126..14878
                     /locus_tag="ACIZE9_001657"
     CDS             14126..14878
                     /locus_tag="ACIZE9_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093520.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14892..16694
                     /locus_tag="ACIZE9_001658"
     CDS             14892..16694
                     /locus_tag="ACIZE9_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6093521.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16971..18011
                     /locus_tag="ACIZE9_001659"
     CDS             16971..18011
                     /locus_tag="ACIZE9_001659"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGC6093522.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18063..20207)
                     /locus_tag="ACIZE9_001660"
     CDS             complement(18063..20207)
                     /locus_tag="ACIZE9_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC6093523.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLRLDKSFWLDLPLKK"
     gene            complement(20564..21937)
                     /locus_tag="ACIZE9_001661"
     CDS             complement(20564..21937)
                     /locus_tag="ACIZE9_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6093524.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="ACIZE9_001662"
     CDS             complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="ACIZE9_001662"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HGC6093525.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="ACIZE9_001663"
     CDS             complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="ACIZE9_001663"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HGC6093526.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23385..24398)
                     /locus_tag="ACIZE9_001664"
     CDS             complement(23385..24398)
                     /locus_tag="ACIZE9_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGC6093527.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24479..25078)
                     /locus_tag="ACIZE9_001665"
     CDS             complement(24479..25078)
                     /locus_tag="ACIZE9_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HGC6093528.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25264..25965
                     /locus_tag="ACIZE9_001666"
     CDS             25264..25965
                     /locus_tag="ACIZE9_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093529.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25975..28686
                     /locus_tag="ACIZE9_001667"
     CDS             25975..28686
                     /locus_tag="ACIZE9_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGC6093530.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29137..30765
                     /gene="treC"
                     /locus_tag="ACIZE9_001668"
     CDS             29137..30765
                     /gene="treC"
                     /locus_tag="ACIZE9_001668"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGC6093531.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30825..32006)
                     /locus_tag="ACIZE9_001669"
     CDS             complement(30825..32006)
                     /locus_tag="ACIZE9_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC6093532.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32258..>33674
                     /locus_tag="ACIZE9_001670"
     CDS             32258..>33674
                     /locus_tag="ACIZE9_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HGC6093533.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYA"
BASE COUNT        10659 a         6038 c         6850 g        10127 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttattt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt taggacggat
    13621 tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg aaagaagaat
    13681 gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata taaagtaaga
    13741 gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc gttgtggtac
    13801 ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac tatgtacaaa
    13861 ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa acagtcaact
    13921 atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg gacttcaagg
    13981 gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg aacaaaaata
    14041 aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca gcactggaaa
    14101 aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga atgtaacaaa
    14161 agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca gcttcgatgt
    14221 agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt cgacactttt
    14281 gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca atcaaaaaga
    14341 tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga ttggctttat
    14401 tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg ctgttcctct
    14461 ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa ttgcagaacg
    14521 tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg gacaaaaaca
    14581 acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag gggatgagcc
    14641 tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg acgaattgaa
    14701 tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg caagttattg
    14761 ccaacgtatt ttattcatca aggatggcgg tatccatcaa gaagtgaaac gtggagatca
    14821 aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg aacagtaggg
    14881 ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt ttaagagact
    14941 acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg tttgaatcaa
    15001 tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca gttatcattt
    15061 tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta tatgcaaatt
    15121 cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg ggagcaaaag
    15181 gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc gcagctactt
    15241 tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta ttagtggatc
    15301 agttagatct caatatttcg cattttacac cttttagtat tcacgggttg ttgatcactg
    15361 ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt tcgattgtca
    15421 aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc aagcagcata
    15481 aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc ggttactata
    15541 tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta gttacgatcg
    15601 tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca ttactaaaga
    15661 aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag ttaaactttc
    15721 gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc ttggcactgg
    15781 gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca gaaaacaatt
    15841 ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa atcaaagaac
    15901 tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg atttactata
    15961 atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat ggaacaccgc
    16021 cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact gtacaagagg
    16081 aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta gtcagtcaat
    16141 cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag gtaaaagact
    16201 tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg aacaatccat
    16261 ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg tataatggtc
    16321 tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg accatgcttg
    16381 ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct cgttatgaaa
    16441 tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt agagaagtag
    16501 gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc ggattacaaa
    16561 tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt acgatattct
    16621 tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga atcgtattga
    16681 aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa gcaaaaatag
    16741 ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16801 ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc acggtctttt
    16861 attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag aaaacggttt
    16921 ccatgtatac tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac atggaaatca
    16981 atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa aatgggacat
    17041 ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata atcgataatg
    17101 aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa aaagaccctt
    17161 atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca ttcaaattag
    17221 atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta catggtggtg
    17281 cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa aacgaagcat
    17341 cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga actttagatg
    17401 tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc caagggatca
    17461 gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta accggtgatc
    17521 cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt gctacgctca
    17581 ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca tttgacttcc
    17641 aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca atgatagtgg
    17701 gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat gctgcggaat
    17761 tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca ggaatcgtga
    17821 tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa ttagtaaatc
    17881 atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt gaaagttttg
    17941 gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac aaaataaata
    18001 taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct ttttaattta
    18061 ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaccttaa caaggttagt
    18121 acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg tcttgccgta
    18181 aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc gttgttgacg
    18241 cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt ccatttgatt
    18301 ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc agttgttgct
    18361 gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat cgcgttcaat
    18421 ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt tgcttctttg
    18481 tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc agtcagtcca
    18541 tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata tttacggaat
    18601 tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg
    18661 ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc gcttgataat
    18721 aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga tgcgtagatt
    18781 ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt
    18841 gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga tgagccgcct
    18901 gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc aaaatcaggc
    18961 gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc atggataaat
    19021 tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg tccccagaag
    19081 acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata ttgctgttcg
    19141 cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata agtcaaacca
    19201 gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc aagatgcttg
    19261 aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca
    19321 attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat accgctttga
    19381 tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga accattgttt
    19441 ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg gtttgtttga
    19501 ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt tgaaccatta
    19561 ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg tgtactaggg
    19621 acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc tttaaattct
    19681 gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata atttacttct
    19741 ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa
    19801 gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat atccaaaggt
    19861 tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat caaagaagga
    19921 gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc agccggatca
    19981 atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg gtcttctgta
    20041 aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt tgtgactgtt
    20101 tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac agacggagca
    20161 atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat aaactagtcc
    20221 ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt tggaacagat
    20281 aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa ataaaacaat
    20341 ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta ttgcatagac
    20401 cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg taaattatac
    20461 caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa gaaaaagact
    20521 gaaatatgtg ataaacatct catacttcag tctttttcat taactattca taagacatta
    20581 ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga ctaacagcca
    20641 gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac
    20701 caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca ccagcagctg
    20761 caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg taaacagttg
    20821 gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc gaacgggttt
    20881 ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca aaattggctg
    20941 ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg atcatgacag
    21001 ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca gcgatgattg
    21061 cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct aaaccttcgc
    21121 caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg
    21181 aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg aggaattttt
    21241 caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac gtatactgca
    21301 tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct gaaagtaaag
    21361 aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat ccattcactt
    21421 taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag acggcattcg
    21481 acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca atcgtagtcg
    21541 ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg atcggcgtaa
    21601 agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct ttcggagctg
    21661 aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga tccatgatta
    21721 tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc tgttttaatt
    21781 tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc gcacatggaa
    21841 ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga atctgctcgg
    21901 acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc cactcactaa
    21961 tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac agttattcaa
    22021 ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta acaataattt
    22081 gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt caatcgattg
    22141 tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa gaccgtttga
    22201 gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat ccccgatact
    22261 taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat tgattacttt
    22321 tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg attgttctaa
    22381 agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa cagaagaggc
    22441 tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa gtgtgctgct
    22501 taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca ctttaaaagc
    22561 agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc ctagtgtaat
    22621 gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca aactgttatg
    22681 atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta taatgatatc
    22741 tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt
    22801 tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta agctactttc
    22861 aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta ggacttcttg
    22921 ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc ctgctgcgtc
    22981 taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc cagatgtatc
    23041 gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc
    23101 tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt tggcaccttt
    23161 acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt
    23221 ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg tgttcatttt
    23281 acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa acgttttagt
    23341 aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt caagggtgca
    23401 gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc tttttctggg
    23461 aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa gattggttgt
    23521 gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc atagccaata
    23581 atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata taatccaaaa
    23641 gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag ttctgctgtg
    23701 atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg
    23761 atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac attttccggt
    23821 ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc
    23881 gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc ttcagatttt
    23941 ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt gattgcatct
    24001 gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt gagctcggct
    24061 agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt gacgaaattc
    24121 tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg attcgtgata
    24181 tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct agcaaaatag
    24241 tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt tttcggactg
    24301 aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac gccggaaagt
    24361 ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct atctaaatcc
    24421 tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt
    24481 atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt gcagttttcg
    24541 gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg caagcatctt
    24601 cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt
    24661 ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga agttgaagat
    24721 caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac atattatctg
    24781 tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca gaagcagtca
    24841 ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct acgttcacta
    24901 aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg tttgtcagaa
    24961 tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt tgcatgtcga
    25021 tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa tcattcatga
    25081 tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc gtttatttgt
    25141 caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa aataaataag
    25201 tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa tggaggaatc
    25261 agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg agaaacgacc
    25321 attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt gattatactt
    25381 ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat ggatacacct
    25441 gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga taaacagctt
    25501 actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct cgttcctaat
    25561 ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc gcttgatcct
    25621 gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc gtcccaatta
    25681 tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa tcccaaactt
    25741 cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca agtattgaaa
    25801 ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac acataattct
    25861 gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt aaggtctgtt
    25921 gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga ttttatgaaa
    25981 acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg acgattcatt
    26041 gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa aactgctgga
    26101 cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc tgatttgcaa
    26161 atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa gatcccagat
    26221 gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa cgaagtgatt
    26281 caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac tgatggaaaa
    26341 ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga agggtataaa
    26401 atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta taccatcacg
    26461 ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc gaacgtcgga
    26521 aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac agatatttat
    26581 tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag caaagcttac
    26641 aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga tcgacccgaa
    26701 gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc acagcaaaaa
    26761 atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga tgctaaaaaa
    26821 cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg aacaatcgct
    26881 gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca attagttgag
    26941 aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga aaaaattgaa
    27001 aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg ttttcaagaa
    27061 tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt tttctttttc
    27121 tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga aaaccgcagg
    27181 gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa aaaatatgca
    27241 atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt aggaacgaat
    27301 cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg gagtgcgctt
    27361 attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat tgccgcattt
    27421 ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc attgcttcaa
    27481 ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc gctgtggtca
    27541 cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa gtcaagaatg
    27601 cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg cgtgggattg
    27661 aaagattctc taagttctgt ttcagccaaa caatttggac cgatcattga ctatcaagca
    27721 atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga tatgctgcag
    27781 aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga attgagaaaa
    27841 aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc tgatttggat
    27901 cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa aacaggaatc
    27961 gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca tatttcgctt
    28021 tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa aaactatcta
    28081 ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca atcgatgatg
    28141 gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga aatgctttcc
    28201 gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa acaaatcgaa
    28261 acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt cgtattatca
    28321 ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc cgagcgtgta
    28381 cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac gatgtacatt
    28441 gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg tgtaggatat
    28501 atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt tccattagtg
    28561 atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac ggttattgtg
    28621 atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt gaaatcgaat
    28681 gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga aacaaacggc
    28741 aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag ctgattgaac
    28801 accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa tactcaaata
    28861 aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa aagcttttga
    28921 acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga tagacaaata
    28981 catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat aaagataaat
    29041 tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat ataagttgtg
    29101 gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga caaagtcatt
    29161 taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg agatttaaaa
    29221 ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat ttggctaaac
    29281 cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta cacagccatc
    29341 gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc aaagaaatac
    29401 cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca tgaatggttc
    29461 aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag agaagagcca
    29521 acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga tacggggaaa
    29581 tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa ccaagcagta
    29641 agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa aggattccgt
    29701 ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa agaaaatgat
    29761 ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga attgaaccaa
    29821 gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc tacgacgatc
    29881 gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt ctttaatttc
    29941 catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc atttgatttt
    30001 gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg taacggctgg
    30061 aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt tgtagctatc
    30121 gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt gaaccgtggg
    30181 acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta ttcatcgatt
    30241 tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga acaaggattc
    30301 acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc tcgaacaccc
    30361 atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg gttaaaagtt
    30421 ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga ttctattttg
    30481 tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc acaaggagat
    30541 tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca atttgaagga
    30601 cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc catcccagaa
    30661 ggattcacag aagccaatat tcttatcgat aattattccg atactgttct tcatcaaagt
    30721 ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa aaacacaaaa
    30781 cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt aaaataatct
    30841 tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt attgtagcgt
    30901 tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata gataggaata
    30961 ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac gattaagatc
    31021 gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa gtcaccgtgg
    31081 agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt agagtcttgg
    31141 aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg aatgatacat
    31201 aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag taagaaacaa
    31261 acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag aaatgaaccc
    31321 aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc tggtgggaca
    31381 atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa agcgacaatt
    31441 ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt gctgatccgt
    31501 tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt cacgtcgtca
    31561 atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa aaattgtcgg
    31621 agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt ctttgcctgt
    31681 tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa aataatcaca
    31741 taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt gatgactggt
    31801 tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt agcgataatg
    31861 attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat cagcgcaagt
    31921 aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg gatcaaacga
    31981 ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataac ttcattatag
    32041 acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc gtcaatcatt
    32101 catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt taaccatatg
    32161 ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc gaatcggaac
    32221 attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga taggtatatt
    32281 ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga aagccgagga
    32341 cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt ttacaaaagc
    32401 aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg attcccacga
    32461 ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct ttgtttataa
    32521 tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag aaggcaatgt
    32581 ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag aaggacatga
    32641 tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac atgtatggct
    32701 agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga ttgaagctta
    32761 cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc
    32821 actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca
    32881 acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat cgattgctgg
    32941 tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac actttgttaa
    33001 agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta ttgccagaac
    33061 gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag gattgacgaa
    33121 tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt
    33181 gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca aaaaagaaaa
    33241 gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc tttcagattg
    33301 ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg atcctgtttt
    33361 tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag aatattatac
    33421 gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga tggcatttac
    33481 gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag aaatcttgac
    33541 ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata aggaaagtgg
    33601 cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact ccgaacattt
    33661 tcatttatat gcag
//
LOCUS       DBBGSP010000030        32568 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000030 DBBGSP010000000
VERSION     DBBGSP010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.030"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(279..494)
                     /locus_tag="ACIZE9_001671"
     CDS             complement(279..494)
                     /locus_tag="ACIZE9_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093534.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
     gene            complement(546..1460)
                     /locus_tag="ACIZE9_001672"
     CDS             complement(546..1460)
                     /locus_tag="ACIZE9_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093535.1"
                     /translation="MNNNEKILHVLDSFEIIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKNAMELNEERRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            complement(1460..2359)
                     /locus_tag="ACIZE9_001673"
     CDS             complement(1460..2359)
                     /locus_tag="ACIZE9_001673"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0000400 - four-way junction DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HGC6093536.1"
                     /translation="MWTVTLPFQPVSAPRPSARRNAADETNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQDLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            complement(2359..2946)
                     /locus_tag="ACIZE9_001674"
     CDS             complement(2359..2946)
                     /locus_tag="ACIZE9_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093537.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNNGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITSKEAKIEDVLTVRELQSLIEYRNKQITNPEYLRKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDTFKKIYLKEIKKD"
     gene            complement(3110..3301)
                     /locus_tag="ACIZE9_001675"
     CDS             complement(3110..3301)
                     /locus_tag="ACIZE9_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093538.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            complement(3374..4276)
                     /locus_tag="ACIZE9_001676"
     CDS             complement(3374..4276)
                     /locus_tag="ACIZE9_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093539.1"
                     /translation="MLLTLLGYLCLILAFFGAIAIIIGQFQTNNPIMRNIGIGIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            complement(4293..4769)
                     /locus_tag="ACIZE9_001677"
     CDS             complement(4293..4769)
                     /locus_tag="ACIZE9_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093540.1"
                     /translation="MPKRKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRILEWLNTNTDQEPLRVISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            complement(4785..5384)
                     /locus_tag="ACIZE9_001678"
     CDS             complement(4785..5384)
                     /locus_tag="ACIZE9_001678"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGC6093541.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGEANVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            complement(5943..6422)
                     /locus_tag="ACIZE9_001679"
     CDS             complement(5943..6422)
                     /locus_tag="ACIZE9_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093542.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            complement(6441..7070)
                     /locus_tag="ACIZE9_001680"
     CDS             complement(6441..7070)
                     /locus_tag="ACIZE9_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093543.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRAKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            complement(7067..8443)
                     /locus_tag="ACIZE9_001681"
     CDS             complement(7067..8443)
                     /locus_tag="ACIZE9_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGC6093544.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTVMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMLIKLVDGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAETRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANPSSKEPSIEKKSAFAIKLEKNKEEKVEQGAKTLEKLQAEKLEKVLRALGK
                     ADPEPQTSNNTNNKQPIASKTKPKANDPKGSENVVITTDKSEKKQINGSTSPIMQKML
                     KAKKQVHK"
     gene            complement(8523..9785)
                     /locus_tag="ACIZE9_001682"
     CDS             complement(8523..9785)
                     /locus_tag="ACIZE9_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093545.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            complement(9798..10145)
                     /locus_tag="ACIZE9_001683"
     CDS             complement(9798..10145)
                     /locus_tag="ACIZE9_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093546.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            complement(10165..11034)
                     /locus_tag="ACIZE9_001684"
     CDS             complement(10165..11034)
                     /locus_tag="ACIZE9_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HGC6093547.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            11337..12782
                     /locus_tag="ACIZE9_001685"
     CDS             11337..12782
                     /locus_tag="ACIZE9_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HGC6093548.1"
                     /translation="MLGVILMMRKQSIEGRNQFAMLTIDDLVPKDHLVRKIDAAIQFD
                     FIYPIVESTYSTYGRPSIDPVVLIKLVFIQYLFGIRSMRQTIKDVETNVAYRWFLGYS
                     FEDPIPHFSTFGKNYVRRFRETTLFEDIFSHILEQAVKAGFVTEDNLYIDSTHIKANA
                     NKHKFTKEMTYGQAKAYQDELEDEINKERIAVGKRPFTWDTESELSLQKISHSDPESG
                     YYVKGEREKQFAYSAHTSCEDNGFILSTLITPGNVHDSQVAIDLVKQSKRAFPNIKRV
                     VADAGYKTPKFVHFLSHLKLYPILPYTAPHGVKGMFRKKDFVYDAYFDCYLCPNNQPL
                     LFSTITRDGYRTYKSNPKFCVSCPLLENCTLSTKHQKIVTRHIWADLMDELEHQRHTA
                     LNREIYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLTFAAMNLKKLATWLW
                     KTKKPMAFYFKIMQRLTKRSGLITNSFLSTI"
     gene            complement(12799..13587)
                     /locus_tag="ACIZE9_001686"
     CDS             complement(12799..13587)
                     /locus_tag="ACIZE9_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093549.1"
                     /translation="MSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWISAVGEEN
                     IEFEIKNMDDLKAKFPFIASKLSQVAEDKSWNELVSFSEKIYDITQEDECVSWEMNNQ
                     YKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYAEYLKTE
                     RDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALSQYSSDE
                     EVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            complement(13693..14493)
                     /locus_tag="ACIZE9_001687"
     CDS             complement(13693..14493)
                     /locus_tag="ACIZE9_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093550.1"
                     /translation="MVGVSKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETMKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            complement(14761..15933)
                     /locus_tag="ACIZE9_001688"
     CDS             complement(14761..15933)
                     /locus_tag="ACIZE9_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
                     /protein_id="HGC6093551.1"
                     /translation="MTQVHFTLNNEEVQSIIEHSVKDDVSKNILTTVFNQLMENQRTE
                     YIQADDYERSESRQSQRNGYYERDFTTRVGTLELKVPRTRDGEFSPTVFERYQRNEKA
                     LLASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLDPMVNEWQNRSLSGTN
                     YPYLMTDVLYIKVREDHRVLSKSCHIAIGITEGGDREIIGFMIQNEESDDTWSIFFEY
                     LKERGLKGTELIISDAHKGLVSAIRKSFTNASWQRCQVHFLRNIFSSIPKKNSKPFRE
                     AVKAIFKFTDIELARTAKNALVGEYIDQPKYTKACEILDNGFEDAFQYTVIGNSHNRL
                     KSTNLLERLNQEVRRREKIIRIFPNRTSANRLIGAVLMDLHDEWLSSTRKYIKFDQ"
     gene            complement(16164..17273)
                     /locus_tag="ACIZE9_001689"
     CDS             complement(16164..17273)
                     /locus_tag="ACIZE9_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC6093552.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKTETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVIGALASLKVLILLIKEFRKA"
     gene            complement(17263..18120)
                     /locus_tag="ACIZE9_001690"
     CDS             complement(17263..18120)
                     /locus_tag="ACIZE9_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC6093553.1"
                     /translation="MKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNSYK
                     EKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGELVG
                     EILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKYFT
                     DLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVGDN
                     SHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKIVA
                     KRRGMKNEE"
     gene            complement(18195..20030)
                     /locus_tag="ACIZE9_001691"
     CDS             complement(18195..20030)
                     /locus_tag="ACIZE9_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC6093554.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKSVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            complement(20079..22469)
                     /locus_tag="ACIZE9_001692"
     CDS             complement(20079..22469)
                     /locus_tag="ACIZE9_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC6093555.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMMLSTLIMPFSAIRAEADVTKPT
                     SAKFIETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKQEGITVKDDGQTFEYTATNTLKKGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            complement(22737..23984)
                     /locus_tag="ACIZE9_001693"
     CDS             complement(22737..23984)
                     /locus_tag="ACIZE9_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HGC6093556.1"
                     /translation="MNMKRNSLGMVLLASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPIENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKPMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            24376..24792
                     /locus_tag="ACIZE9_001694"
     CDS             24376..24792
                     /locus_tag="ACIZE9_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093557.1"
                     /translation="MNKKRKLSVLITLVSILTILSVILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETGTTTKKYKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            complement(24809..25546)
                     /locus_tag="ACIZE9_001695"
     CDS             complement(24809..25546)
                     /locus_tag="ACIZE9_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093558.1"
                     /translation="MADHKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(25968..26531)
                     /locus_tag="ACIZE9_001696"
     CDS             complement(25968..26531)
                     /locus_tag="ACIZE9_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093559.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            complement(26518..27045)
                     /locus_tag="ACIZE9_001697"
     CDS             complement(26518..27045)
                     /locus_tag="ACIZE9_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093560.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            complement(27068..28441)
                     /locus_tag="ACIZE9_001698"
     CDS             complement(27068..28441)
                     /locus_tag="ACIZE9_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HGC6093561.1"
                     /translation="MKKSKRKIATLLMLMVQFTGIAMSVITINPQVIHADGIATYDAQ
                     FNCTTEGSGSGTDSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWK
                     QESGIDPRAVEGYYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGS
                     WWTTEAQLDFMFKGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVR
                     GENAKEIWKYMKSKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDD
                     ANSGSGSIGKEGKINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQ
                     GQCTELTWAYMSQLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWA
                     VGDAGHTGVVIAVFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGK
                     AKFEIEK"
     gene            28525..29004
                     /locus_tag="ACIZE9_001699"
     CDS             28525..29004
                     /locus_tag="ACIZE9_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093562.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            complement(29208..29351)
                     /locus_tag="ACIZE9_001700"
     CDS             complement(29208..29351)
                     /locus_tag="ACIZE9_001700"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093563.1"
                     /translation="MLSDLFILLIYLGVSEIIAYFLFVIANYGISSAIVQMFRLPVSE
                     LKK"
     gene            complement(29354..29671)
                     /locus_tag="ACIZE9_001701"
     CDS             complement(29354..29671)
                     /locus_tag="ACIZE9_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093564.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            complement(29782..29964)
                     /locus_tag="ACIZE9_001702"
     CDS             complement(29782..29964)
                     /locus_tag="ACIZE9_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093565.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENIEDLRLIGE"
     gene            complement(30001..30801)
                     /locus_tag="ACIZE9_001703"
     CDS             complement(30001..30801)
                     /locus_tag="ACIZE9_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093566.1"
                     /translation="MSEDLRELKLRKKQYDQYFSGLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSMSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRETLVWKEEK"
     gene            complement(30938..31246)
                     /locus_tag="ACIZE9_001704"
     CDS             complement(30938..31246)
                     /locus_tag="ACIZE9_001704"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093567.1"
                     /translation="MYESEFINLTFLNSVFIDYVITTKRIGSYSSTYASLVPMLNSMS
                     RFLKEREKKELQYIKEIMPDFEMHEWQIALSDWKLANKVRRITPFQAKRFLRAMKFVQ
                     "
     gene            complement(31353..31661)
                     /locus_tag="ACIZE9_001705"
     CDS             complement(31353..31661)
                     /locus_tag="ACIZE9_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093568.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIERCH
                     YGQHFWTGEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSDLMMKKV
                     "
     gene            complement(31823..32353)
                     /locus_tag="ACIZE9_001706"
     CDS             complement(31823..32353)
                     /locus_tag="ACIZE9_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093569.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            complement(32369..>32568)
                     /locus_tag="ACIZE9_001707"
     CDS             complement(32369..>32568)
                     /locus_tag="ACIZE9_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093570.1"
                     /translation="IHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELK
                     KQNVDRNALKHEILELIMQRI"
BASE COUNT         9300 a         6545 c         4591 g        12132 t
ORIGIN      
        1 catctttaaa gaaatacgat caaaaaacat aattcccata ttatttgctc gttcaacaat
       61 ttgaaatata tctattagtt cttctttttt cataactgct cttcctttaa cttgttaatc
      121 taacttgctt acaaatatat cctaccacat ttgtgtacta tctgtcaata tttttttgtg
      181 tataaatgtg tattataaaa caaataattt tacacaaaca aaaaagagcc taactgctct
      241 tagcaataag ctctcatcac tgctcctcgt gaatttagtc agtacaatgt atttgccttt
      301 tctttgataa aatccttata cgaaaaattg ttcaaccaaa attgttttag cactaccgaa
      361 tttttgtttc catcattcaa ctccaattga ccaaatctgc tgatcatatc atcaatttca
      421 tcaattatct cttgtgccat catgccgtct tctagacgtt ctaatacgta caattcaaaa
      481 acatcccttt tcattcaaaa tgcccctttc aggttacctt ttgccatttt atgggctaac
      541 tccgcctact cagctttttt tatataccta ctgatatttg ctttcgtatt tcttggcata
      601 ccacctgctt gcaggtaatg ttcacgataa taagcatcta gctctgaaac agctttttct
      661 aatctattcg ttgcattcaa cactgagcgg tattcacgtt tttcccttaa tacacgtctt
      721 aaatggttca tcgctgatat ataaggctta tagtattcca atacagtata tcctctagaa
      781 atataggcaa ttggatttct agcttcatgg atcaattcta aaatatctgt tggatcaggc
      841 ttatccggca tctcttcttc gatttccata atactgatca agtagtccaa tccggaatca
      901 tcgactccat aactttcaca ccattctttt aggttgttca agtcatgaat aacatcttca
      961 ggatcaaact ctctaaaagc agtgatccct tggctataat attttatata ttccattgcc
     1021 gattcaaaat cctctggcgg tatgaaagct tcaatttctt cttcatcaat cgctttcagc
     1081 actattccga tacctgagtt tgaaggatat tttctcaatc cttcttcaat taaatcctca
     1141 tctattcgtc ctttttgaaa catcaccaat aattgttcta acagctgatc taaaaccctg
     1201 cgctcttcat tcagttccat tgcattttta acttcttttt caccgagttc aaagtaagct
     1261 ttgatcaact tttcttgttc ttttcgttca actaatttct tcttcaagtc attcatattg
     1321 agaatgaaat ccatgtgatt actcttttgc tgattgacaa aatcatatct ttgttccaaa
     1381 acatcccgat atttttttag ttcttcttga attatttcaa agctatcaag tacatgaaga
     1441 attttttcat tattattcat cagcccatct cctgtagtct cacgtttgtt ttcgactttt
     1501 caaaagtatt gtatttaaaa gcaattaacc ctacaaccct gctatctttg atgcctattt
     1561 ccttgttaaa aattccgtcc aatgttcctt tgactaaatt atcaatatcc ggctgtgaag
     1621 tacgcatcag tgaatcaagc tttttcttat cttttctcac ttggtaaaaa taatctatct
     1681 gagctataac ccccatagga gcattcatta cctttttcag ttgatcattt accaaatctt
     1741 tctctttaag cgtattcttg atattttcca aatagtcgtt gtactctttt ggatagtaag
     1801 tgataatccc atttcctcta aatttagact ttggtcttgg cgttgctact ggtttaaaat
     1861 caaatgtagc ttcccatata tctccgttca atccttcaga agtatcccac tcaaattctg
     1921 aatatcgttt gatcctcaca actgtttttc cttcgttcgc cacattatat ttaaaagcaa
     1981 ttaagcctgt gatatggcta tctcgtatag ctgagatgtt aaaaatacca tccatagcac
     2041 tttttactaa attatctaaa tctggcgctg ttgtcttcat aatgttatag acttttttat
     2101 agctttttgg tatctggtag taaaagtcca cttccataat tgcgcccata ggatcattta
     2161 caatcgagta aaattcatca tctaataaat cttgatcttc gataaagctc tttatttttt
     2221 tcaaataatc aagatacttt ttatcatagt aggttgaaat ccttttctct gctacgtcat
     2281 tagtttcatc agcagcattc cttcttgcac ttggtcttgg tgcagataca ggttggaacg
     2341 gtaaagttac agtccacatt agtctttttt gatctctttc aaatagattt ttttaaaggt
     2401 atcaaggctt aaaggagcta ccttttgcat cttccggatt ttatttactt gttccaattg
     2461 tttcaataga ccatcttctt ttctaaggta ctcaggattt gttatttgtt tattccgata
     2521 ctcgattaat gattgaagct ctcttactgt taaaacatcc tcaatttttg cttctttact
     2581 cgttatcttt tttagatacc ctaatactgt tggataagat ttgccgatca cttctgcgat
     2641 ttctttttta ttgtactcac caaattttcc aagcaaccag tcattcatga tcttacttga
     2701 tacttttggg tatacaagaa ttgctttttc aatggaatga ctgccattat ttctgatcag
     2761 ttgactatct ttacactcaa ctgtaacgcc atcacctaaa tcaacaacat attgccaaac
     2821 gcctcttcga ttcttattaa gagaaataat cgttccctct ttatctctat aatcctttga
     2881 taattcactt actgttgtaa ctctttcccc aatgctaaaa tgtctaatat cattattgtt
     2941 ttccacttat tatccctcca atattgctgg ttatctcttc ctctgacaag gaactatata
     3001 tcatataaag aattttaaca ttattcggaa tgagtgtaaa gaaactttat ataaaaagag
     3061 tgatttagtc taagaccaaa tcactctttc ttttttatta attatattgt tatctgatag
     3121 acctattagt aaatgcacgt cttattgttt gatcattctc gatcaattct tctaacaact
     3181 ctgaaactgt tactttctta cctcttgctc tttcttcttc tttagctcgc ttttctaaat
     3241 atttaacaga agctattttt aaagtcacat actttctaac tttttcttta tttactacca
     3301 tcagctatca tctccaaggt gtcacaccta tatattattg gtgtgacacc atttgtttat
     3361 tataactttc tggctattta gccaatttaa tcgttaatgc ttcgtttgct gtagaatctc
     3421 caaaaacttt accgtcttca taaactacat gaactggcaa atctgcaccg tctgaatctg
     3481 gtttagcagt accacgatac aaaccaatta ctctttttcc tagttctctt gcaaccgtaa
     3541 cttttttatc ctgatccata gattcaactg aattgaataa ggtaacatta atcatttgct
     3601 tttcagtatc caatttaaca gttttgatag ctttgaagac ttcagtgtta aaccgatcag
     3661 ccatagaacc agaaacagat tcaaacgatt tgactttttc aggatcaaaa tcaattttat
     3721 ctggtagttc cgcttcgaca gtagaacttg attcagttgt actttcttct gtagctactt
     3781 cttttttcgc tgattcgata atctttttcg ttgatgtttt atttattttt acatctttat
     3841 agtattcttc tccatcaacg ttaaaaacca atgtcagctt gtgtacaggg ctattctctt
     3901 taactgtata aaacacttca aattgtgatt gagacggctt aatagtagcg agaacgtcgt
     3961 ctgatgcttt cttgccatct tccttcactg tcagcgaaac atttttataa ctcgttacat
     4021 tttcaaatgt tccatctatt actacccttc ccaaagaatc tggagcataa ctattattaa
     4081 ctcccgatat accaaattgt ttatcgttac ttccaaaaat cttagtggca ttaaacacaa
     4141 taaaggttac aatcacaatt ccaatgccta tgttacgcat aatcggatta tttgtttgaa
     4201 attgaccaat aattatagcg attgccccaa aaaaagcaag aattaaacat aaataaccta
     4261 acagggttaa tagcatgatt catcacaact ttctattctt tatttttctt tttggttttc
     4321 gtttgttcaa actcatgctc atttagataa gtaatcaata aatctcgcat ggatttgcta
     4381 tccttactta gcgtatcaaa cgcttcttgt aagtcagcat ccttctctac agcattaaac
     4441 caatgcttcg ttccaaattc aaaaagatta ctaatcactc ttaacggttc ttgatcagta
     4501 ttcgtattaa gccattcaag tatccgttgt tgagctaatc ctaatttact ttcgtcttcg
     4561 tgatttgtac gtgcttcata gattttagtg tgtatatcat caaaatagtg gattcgttct
     4621 cttagcgctt cacgttgttc gtacatagcc cttttatttc taacttcttc gtctattgtt
     4681 tcaatctttt ttcttaacag tatttgaagt gataacattt ctgagacaga caaaaacact
     4741 ggaattttct tttcttttct ttttggcatt tttagcactc ccttttaatt cttttgtttg
     4801 atcaatgaaa cgttctttag aataaatccc aagatcattc cacagacaaa tccgattaca
     4861 tgtgacaaga catttgcctc gcctgattca aaagtagata ccaataaaat gccgattatc
     4921 aataatacaa aaacacttag taataaatgt ttcttgctat caaaacggat gtatgcaatc
     4981 gcaaataaag caatccatcc aaaaatacct ccactaagcc ccatacttac gatgttgctg
     5041 tgtagcagaa aaggaactaa gcttcctaga aatcctgata tgattaaaac gatcaataat
     5101 gttaaccact catactgatc attcagtgct tcttcaagaa ctactaagaa caataaatta
     5161 gaaattaaat ggtacaagtt aatatgagaa acgatagaaa tgaatatatt cgggaacaag
     5221 tgtccttcat acaaaccacc taaagcaacc atttcctttg cactcaatgt atttccaatt
     5281 atgctttttc caatctgcaa aaaatcaaac aggaaaatca atacacaaac aaaaactaca
     5341 gtcgctacta ggtatcgact actatttttg tttttttctc tcattcgcta cttcctttgc
     5401 tttagtaact gccgattctc catattctct aaaaagagtc gatgttagct ttcctctcgg
     5461 aatattgtat ttttttaaaa tttcagttgt tgaaagattt ttttcaaagt cttcaataat
     5521 ttgtttatga agatttattt tagccaaatc attggttgtc aaaacaggtt ctttagcttg
     5581 aatatcgcct tgacgaatta acctttgaat tttatttttg ctttttaaaa aaggatattt
     5641 ttcaattaaa gggtcaattg cattcccttc atcaatccac ttacctattt cttgataaac
     5701 tctcttttga aattttttcc tcagctcaat cgggttcgga aaaacattgt gcttaaaatc
     5761 gtgtgatact aggctctttg atttgcctaa ttcatcagcg acttcttgca ttgtaatttt
     5821 gttttcgata tagcattgga caagagcatt atatttttta gggttattat tatttattgt
     5881 catgttctta cctacgttca ttgctaattt tttggtattt ttctgtttgt gtattgcgat
     5941 ttttaaaagg catttcctaa tacgttaaat tttgataatc ggttcaattt tactgcttta
     6001 tcaatttctg cctgtgacca aggttctatt aaacgcattt ggtacgtcac tagcagatcg
     6061 acatgttcat attcaaactt ttctattccg taaatctgat aaaatatttt ttcttcgttg
     6121 ttactataag gaatcactgt tccgatctta aatatgtttc gtgtgttgtt tacaccaatt
     6181 tcatcagtaa tcttgtgtct atattctaat aacacgtatt tcttatacct gcttgtcaga
     6241 tcaggtgaat agttaacaga ttgacaaacc aagtcactgg ttatacgtgg atcacctatt
     6301 ctgttaattc tcgtgttata gattccgata ataatatagt ttttatcttt atattctata
     6361 gtttctccca cttctaactt ttgattaaag cctgttctat ttgcttcaaa aagttctagc
     6421 aatctttttc acctctactg ctactgccaa acaaatttag ctttatcatg ccatgtttca
     6481 gacattactt ttttaccatt ttcgtcaaat atcaccgctt cccactttgc tgttccatcc
     6541 ggctgtttac aaatatctgc aaaccatagg atcgtttttc gatcgttgaa tttccttact
     6601 ttcttctcaa atttattgat ctgaactcta ttttgattgc tgttccaacc tactaatagg
     6661 cggttatctg attctgtacc atgaaaacca atgggaacga tgtgggttct atcaaatgct
     6721 tcttttcctt ctggatagag cattggtcta agtttcctac gtttcaagtc atctcttgct
     6781 tgataccgcc atgccgattt tggattgaat ttaatagcta tttgatgctt gcttttgtca
     6841 tggtaaaaat atgcgacatc ggcttcagct ccaagcaact tttctcttgc actatttgat
     6901 tcaaacggtt tattcacttc taaaaccttc acccctaaaa tgccatgatc aagcatctgt
     6961 ttaggagtta gtaccgcttt tttatctctt ttcttcgctc gtttcacaac tacttcatct
     7021 gtatatttat atggagtaag ccatcttaaa aaagaactga cgatgatcat ttatgcacct
     7081 gtttttttgc ttttaacatt ttttgcatga taggtgaagt acttccattt atttgtttct
     7141 tttcagattt atcagttgtg atcactacgt tttctgagcc ttttggatca ttagctttag
     7201 gtttggtttt agatgcaatc ggctgtttat tattcgtgtt gtttgaggtt tgcggttcag
     7261 gatcagcttt tcctaatgcc cttaaaactt tttctagttt ttctgcttgc agtttttcta
     7321 gtgttttagc tccctgctcg actttttctt ctttgttctt ttcaagctta atagcaaacg
     7381 cactcttctt ttcaattgat ggctctttag atgatggatt tgctaaaggt gtgttcaaat
     7441 ttcttttagc agattttctt acaggagctt taccaattcc accaaaatcc tcgtcttcac
     7501 cgccctcacc acgagtttca gctacgattg ctcggtaatc aacatattct ggttctggca
     7561 tagtatttct aaggtgattg aagattgttt caatttcttt gttactgatg taagctccct
     7621 gcgctctaac catacttcca tcaacaagct taataagcat atctcccttt ggacttagac
     7681 tttctccacc gccttcatct aatacaatcc tactttctaa atcacttgct accataaggc
     7741 aaacacgtga cggaaaattg gctttgataa taccagtgac aactgttgat cgaggagatt
     7801 gtgttgctaa gataacatga atacctgctg cccttgccat ttgtcctaat tgaacaatca
     7861 aaccttctac ttctttatgt gttccaacca actgtgaata ttcatcaact aataagatca
     7921 catagggaaa tctatctaat ccattttttt cggcatattc gttatatagc gtgatgtttt
     7981 gtaaccctgc tttttccatc agtttgtaac gttcatgcat caagatcaca agatattcaa
     8041 aaaaatcata agcttcatcc atatctgtaa ttggatcagc caacatgaac ggcaattttt
     8101 tgtatcttcc aaattcaacc ctttttgggt ctacaattcc tatttttaat tcatcaggcg
     8161 ttgagtgaca cattactgta acaagaattt cattcagtaa tactgatttc cctgatcctg
     8221 tcgttcctgc aaccaacatg tgtggcattt cgctgatgca aaaatgagca attgtgccat
     8281 caggcttaat tccaaaaata gcatctgttg ggtctttagc ctttgtgttc aacatattga
     8341 cactgaattt tccattaagc tttatattag gttctttatc tagcaaaata gattcagctt
     8401 tttcggctct ctttttgact ttctctaata atttcatagc catttctatt cctcactttt
     8461 ctcggtactt ttctgtttgt gaactggtag tttgtatttt ctgtttctat ttgtgatgtc
     8521 ttctaaaaca cgctattgat cattgatggt acatcaattg gaatacgatc attttctcct
     8581 aatggtaaag taatttgaat acgccctgcg ttgatccgca cgattacacc tgatatatgc
     8641 aagtaagttt caatttcttc tttcattgag cttagttgaa tttttctggt acgagataaa
     8701 gtaaacaaat attcaataga tgtattccca acgtgcatat ctgttagact tgcaggtacg
     8761 tcagcagaag atagataaag ttctaaagat tgcttttgag tttcggcata ttttctagct
     8821 ttttcggttt ggttttggat atttttggaa ttatcggcaa agagattgat tggaaaagaa
     8881 aattgtgaat ttgaaactgc gattgaagat gttgctcttt ccgtttcttt gtttttggta
     8941 cttactcttt ccttacgttc tctttcaata tttactgatg ctcggaaaat gaaataatcg
     9001 cctgaaactt catcttcttt ttcaccaaat ttggctcgtc cgcttgttgc tcttgtcagg
     9061 atcgacccta aatcttgaat ttgtcgtaaa actgtttctc taactttctt cccttttggt
     9121 tgcgggattt ttacgatata ttctcgaata tcttcattga cacttagatc acgtcttgta
     9181 tgaacagaaa ttttgatatt tttaagcgtt gatagcacat cggattctaa ttgcgttttg
     9241 tttcgttttc tttttttgtt gttcgtttca tctcctataa tcttgtttgg atcatacttc
     9301 acatccatag cttctagagc ttctcttttc aaccttctac tttccatatc atcaaaaaat
     9361 ggtctttgtt ctccatagtg atgcctgaac atcaaagtaa ccaaatatcc aacaaagaat
     9421 accgttcctg cttctaatac taaaatagag atgtctacca agtgtagctt tgcaaaaaag
     9481 ctttgtacat tatatgaata acttaaataa ttgggaaaaa acgcattgag taactcttta
     9541 aacatctctt ttaatcctaa atcatctgtt ccgttaacat catttaacga gacaagaata
     9601 cttactaagg tatctacaag cagttgtaca acctttgtta cccaatgcaa aatatatatg
     9661 ccaattgcac caactaccaa tgcacgtcca accagatata ctgatttaga aaaactggct
     9721 acaggataat atttttctcc atcgcttcgc ttatattcct ttaattcaat ggatttttcg
     9781 ctcatctgaa tatctcctta ttttctttct gattttggtt catcgtcact tatgctgtcc
     9841 tcacacatct gcgtatcttt aggaatgatt actctgattt cgtctaacat ttctctctca
     9901 atgatcatcg ccccttttgt actaacagtt ttctctgata attcaacaca tttccctatt
     9961 tcagaatctg gatcaaaaat agcctgttct acgtcaaaat gattcttagc tacatacacg
    10021 atactcattg tttctaactc tctagcaact gaatatttac ccttcttcag aagatagtag
    10081 ccatttcctt tttttattcg atttgcaact gatttatcta atccattgat gcttattgtt
    10141 tccaattctt caccttctca atttctaatc tcttacccaa gtaccatttt gatagttgat
    10201 gttgattcct ttttgattgt taaatacata aacattaagg tttaccgttt ttccattatc
    10261 gttaactgag aaagcttcga catgagaacc acgaggaact aattcattcc ctttataaat
    10321 tggatcaact ttatacaata ctttttcatt cttattttta tagattgcat cacgtacaat
    10381 cgtttctgag taagccatcc ctccattctg atcatttttc ccaacatttt gcgctctcgt
    10441 tccaagtgtt aaattgtgta cctccatatc tcctcctagc gaccatgcta atgaatgact
    10501 tttgttatag agataacctt tatagccttc tagctgagtg atttcattgt ttgaatcttt
    10561 gccgacccaa gtatctctct cttgatcaaa tactccatcc ttgtattctc ctgcaatatg
    10621 gacagaactt ttgaaagatg gacgttccac atttttagat gagtgagaat ttacagcatc
    10681 ataggtgatc aacgcttcaa catctcctgc tcttccaagt tgatctaaat ctgcataatt
    10741 tacccaaaag gtttgactgc ctttttctga taatgcttca tggtcttctt ttgtcagtgt
    10801 atatttccca tcattaatgt ttacgatatt atttggatat ttgtttggat cataacgtat
    10861 ccctaaaaat tcttttgatt cactgtctgc tttattacct acctgaacac tacttttgat
    10921 ctgaaaatca tgttcctgag tactgttatt ctgaaagtaa cccttgccac taagaccaac
    10981 cgcaactaaa accaaaattc ctaacaacga tcggctaaac ttcttctttt tcataccacc
    11041 attcctttta ttgtgttatc ataataagat aaatatataa taaactatat tgtaaatttt
    11101 gtcaaatgta tttttattta ttcccactat aaaccttgat atatagccaa tttaaaaaag
    11161 gatggcaaaa aattatcaag ttaaaaaaat aaattttgaa ccaaattatt tttaataaaa
    11221 tagctagttt ttttatcaaa aaaaatagag cttttcagct ctattcagac tgtagacaaa
    11281 ctcctaaatt tggagtgttg tttgcagttt tttgttttat actaattgta taaactattc
    11341 tgggagtgat tctaatgatg agaaaacaat cgattgaagg tagaaatcaa tttgctatgt
    11401 taacaattga tgatcttgta cctaaagatc acttagttcg aaaaattgat gctgcgattc
    11461 agtttgattt catttatccc attgtagaat ctacgtattc aacctatggt cgtcccagta
    11521 ttgatccagt ggtcttaatt aaattagtat ttatccaata tttatttggt atccgttcga
    11581 tgagacagac aattaaagac gttgaaacaa atgttgctta ccgttggttt ttaggttatt
    11641 cattcgagga tcctatccca cacttctcta cttttggtaa aaactatgtt cgaagattta
    11701 gagaaacaac tttatttgaa gatattttct ctcatattct agaacaagct gtaaaagctg
    11761 gcttcgttac ggaagacaac ctttatattg attctactca tatcaaagca aatgccaata
    11821 aacataagtt cacgaaagag atgacctacg gtcaagcaaa agcttatcaa gatgaattag
    11881 aagatgaaat aaataaagaa cgtattgctg taggaaaacg tccttttaca tgggacacag
    11941 aaagtgagtt gagtcttcaa aaaataagtc attcagatcc agaaagtggt tactatgtta
    12001 aaggtgaacg agaaaaacaa tttgcttatt ctgcacatac ttcctgtgaa gataacggtt
    12061 ttatcttatc tacattaatc acaccaggaa atgtgcatga cagccaagtc gcaatcgatc
    12121 tggttaaaca gtcgaaaaga gcttttccaa atataaagcg tgtggttgct gatgcaggat
    12181 ataagacgcc taaatttgtt cattttctgt cacacttgaa actctacccg attcttccat
    12241 atactgcacc tcatggagtg aaaggaatgt ttcgtaaaaa agactttgtt tatgatgcct
    12301 attttgactg ctatttatgt cccaataatc aaccgttgtt attttcaact atcactcgtg
    12361 atggttatcg aacctataaa tcaaatccaa aattctgtgt gagttgtcca ttacttgaaa
    12421 attgtacttt gagtacaaaa catcaaaaaa tagtgactcg acatatttgg gctgatctta
    12481 tggatgaact tgaacaccaa cgccatacgg cgttgaatag agaaatttac aaaaagagaa
    12541 aacaaaccat tgaacgaata tttgcagatg caaaagaaaa gcatggtatg cgttggacga
    12601 aatatcgagg tcttgaaaaa gtcgccacgc acacgatgct tacgtttgct gccatgaatt
    12661 taaaaaaact agccacatgg ctatggaaaa caaaaaagcc tatggctttt tatttcaaaa
    12721 ttatgcaaag actaacaaaa aggagtggct taattaccaa ctcctttttg tctacaatct
    12781 gaatagagct tttcagctct attcaatatc attttgatca attaataatc gtacactcca
    12841 attaaccgag ttttgatcac tcaaatattt ataatctttg tcatcaaaaa ccagttgcca
    12901 aactctggta cgaacagttt cttcgtccac ttcctcatct gaagagtatt gcgataatgc
    12961 ttcttcaact atatacttta caacttcctc aaaatcagta ggaactttat caataaccac
    13021 ttcatagtct tcttgtttta cgatattggg atcaatatgt tcatccaaac atacctcagt
    13081 gagtttttct ttcacttctg tatctctttc tgtttttagg tactctgcat agtcttcctt
    13141 agaccattgt ttttcaagat catccgctat acttttaata aaggattctt tatttaacca
    13201 attatctgcg gtatctatac cttcaaactc aaaagctgtt ccttctatac gtgatttgac
    13261 gaaagcgtca attttcttgt attgattatt catttcccat gaaacacact catcttcttg
    13321 cgtaatatca taaatttttt cggaaaaact aactaattca ttccacgatt tatcctcggc
    13381 aacttgactt agtttcgatg caataaaagg aaattttgct tttaagtcat ccatattctt
    13441 gatctcaaat tcgatatttt cttctcctac agctgaaatc catgctgaaa gattgattgc
    13501 aatatcgcta aagtcttcta cattttcgac atttcctgta ttatctttta ttactgcttc
    13561 taaagccata tcggttgttg cactcatggt ttgatctcct ctcataatag agcaaaaagc
    13621 cggtttaacc gactttttgc atggtacgtt ttgtttggta gttttctgct tgtgtttatg
    13681 ttgaaataat ccctatagct cttcttttaa tagttcttca actttatctc ttaactctcc
    13741 ctgaccactc tctaatagat ttaaatagct catcagaata tccgtttcat acgtttttaa
    13801 ttcagctcta tactcacttt ctgaatatga tcgtaaatac ccatcattgc taaatgcaac
    13861 tagatcatct tgaaagttcc attctcctaa atttgtttta cttactgctt cccatggact
    13921 attactaaac atttcattaa agaaatcttc gtcattttga tataccttca attcaggaaa
    13981 atagttgctg tcttcattga tttcttgcac catttttcca agttcttctt cagataattt
    14041 accttccaat aattttactt tttctctgtc atttgcataa gccatttgaa cctctccttt
    14101 ttctttttca atttcttcag gtgtttgttt tggcgtaact ttcaaatcta ttccattgcc
    14161 tattagacct attagataac catagaacgt tttaaagtca cttgtagcaa gagatttggc
    14221 atcagggtat gtatcccctc caattttatc taaaacaaaa tcagcaatcg ttacccaagg
    14281 agaatatatc gtacatacta catcccatgt agcatcttca atattcgtcc atgtcggaaa
    14341 gtcattttca ttcaaatagt cttttttcat tgtttcgatc agagtttttc cactttcgtt
    14401 ttggcttaga tattcaacaa attctgcacc atcaaacctg ctactaaata gtttagctaa
    14461 tgagtctaaa gctgtttttg atactcccac cattactaca cctcctatta atattttacg
    14521 atgacttgtt tttcattcac aaataagatt ttctacatct tatctattgc tttatagctt
    14581 ttccatacat tatttctaaa tacaaccaat aaccctatta aattaagctt ttgagtttat
    14641 cttttctaat aatattctga taaatattct gataaaaaaa tttattgtat ttttttcttg
    14701 actttttcta gtcaagtcca taatcctgtg taaaatacta tacaatgttt taccggtctc
    14761 tcattgatca aacttaatat attttcttgt agaactgagc cattcgtcat gaaggtccat
    14821 aaggacagct ccaattaatc gattggcaga cgttcggttg ggaaaaatcc gaataatctt
    14881 ttctcttctg cggacttcct ggttcagtcg ttcaagaagg ttggtgcttt ttagccgatt
    14941 atgactattt ccgataaccg tgtattgaaa ggcatcttcg aagccattat ccaatatttc
    15001 gcaggctttt gtatatttag gctggtcgat atattcaccg actaaggcat tcttagctgt
    15061 tcgagcgagt tcaatatccg taaacttaaa gatcgctttt actgcttctc taaacggttt
    15121 tgaattcttt tttggaatgg aactgaagat gtttcttaaa aaatggacct ggcatctctg
    15181 ccaacttgcg ttggtaaatg acttacgaat cgcagacact aggcctttat gggcatcaga
    15241 aatgatgagt tctgtcccct ttaggccgcg ttcttttaag tattcaaaga agatggacca
    15301 tgtgtcatca ctttcttcat tttgaatcat gaagccaatg atttcacggt cgccaccttc
    15361 tgttatcccg atcgcaatat ggcagctttt agaaagcact cgatggtcct cacggacttt
    15421 tatgtagaga acatcagtca tcagataagg ataattcgta cctgagagtg aacggttctg
    15481 ccattcgttg accatcgggt ctaactgctc agtcaggcta gaaacaaaag atttcgatac
    15541 agattttcca catagctctt caacaatctt tgaaacttta cgtgtcgaaa cgcccgaaac
    15601 atacatctca agcattgaag cgagcagtgc cttttcattt cgctgataac gctcaaacac
    15661 cgtcggtgaa aattcaccat cacgtgttct aggcactttt aattcgagtg tacccacacg
    15721 agtcgtaaag tctcgctcat aatagccatt tctttgactc tgacgacttt ctgaacgttc
    15781 atagtcatcg gcttgaatat attctgttcg ttgattttcc atcaattggt tgaaaacagt
    15841 ggttaaaata tttttagaaa catcatcttt taccgaatgt tcaataatac tttgaacctc
    15901 ttcgttgttc agtgtaaaat gtacttgggt catgtaacgt cctcctgggt atgtttttgt
    15961 ggttaaaaac attgtaccgt aaaagggctg ttacatggcc ttttatcttt tacacaatta
    16021 tatggacttt atcctttttc tttagaatta agatcagttt tgattttatt taaaagtgaa
    16081 tctagctcta ttcaaaataa aaaagagatc aataatagta tcaatccctt tttactgtac
    16141 tctatcaatt tttataatct tcattatgct tttcgaaact ctttgattaa aagaataaga
    16201 acctttagac ttgctaatgc tcctattaca gtccaaatga ctaaaagcat tttctgatgt
    16261 ttattggtaa ttcctgtaaa tattgaactt gccttttcag caaacgttct gtcttgcatc
    16321 tctacgctac cttgttccgg aatattaaga tcattatttc catctaattc cttgttggca
    16381 cgatcaacat cttcaaataa atcattagaa gatgtaacag tttctgtctt atctgaaacg
    16441 gactcgctat caatggcatc agcgtatgcg gtattgccaa ctgttacttg tggcgtgatg
    16501 tattttgctt tttcatctct tagacttcta actaataaac gatcgtagtt ctgaggatat
    16561 ggatgacaag tataaagtgt taacatatct aaatcaggaa tatcagtcag tgttgaattc
    16621 tgaccgtaat ttctaataac gtctgttcgg aaaaccgtat aaactgcttt ttcaccaaga
    16681 taatctatat aaatgtggtc tccggctact aattgatcaa cataaagaaa ttgtggtgac
    16741 gtataaccgc cacgatgacc tgctattact gtttgatgac ctttacctga taaaggtaga
    16801 ctagtagcac tcatttgtgc cacacctcta tataaatgct cctgtgaagc gcctagaaac
    16861 aaaagctcta gcacatttat ttttggaata tagacataac caaccgctcc tgaataggta
    16921 gatggttcaa aatctttcgt ttgatttttt gaaaaaacat ctcctgtgta tggattgacc
    16981 tttccttcag cttcacgaat atcaaatgat ccaccgtctg tttcctgagt attgtctact
    17041 cctttatctg ttttctgagt attgtctaat ccttggttac cgctgttcga ttttatttgt
    17101 tcgacttttt ttgccacttc ctcttttgaa ggagtttgtt ttttctcaat tttctcttgg
    17161 atttccgcca cattctcttt tgttttgaat tgatgataga gctgatttgc aggataaatt
    17221 gttaaaacca aagtgcaaat aagagtcaaa aaaagtagta ttttattctt catttttcat
    17281 tcctcgtctc tttgctacta tttttttaat aatgactatc acagctatta ttaataaaac
    17341 ccctacaact acgataggat accagttcat ctgcgccttt acctttaaat cttctttctt
    17401 cttttctttc tcaacaatac ttttttggta aggtatgcta acccctctaa cgagtaacct
    17461 atgagaatta tctccaacag gtgtacatgt cataagtgtt acataatctt ttcctgccac
    17521 aggaagcaaa tcctcaaatt cggttggtag aattgttttt atccgatcta cttgataagc
    17581 aagttttttc cctgaaatat caataaaaaa tttatcacca agtttgagca actctaaatc
    17641 tgtaaaatat tttttattag gaatgcctga atgagctgat ataacagaat ggtttccaat
    17701 cccaccagtt ggataatcag ttccggttaa tattcctgct cctgctgata gttggaaatc
    17761 gtttacacca tcataaattg gcaaatccac attaatcttt ggtataagaa tttcacccac
    17821 taattcacct aatttatcct tctgaagatt tccatttgac ggaatattgt tattatcttc
    17881 aggaatcgtg actgaggttt gttctgtgtc ttttcgtttc ctattaactt ctgaatatct
    17941 cttgaagact tcttcattct ccttttcaga agcttcatca tatttttcct tataggagtt
    18001 tagtgtttgt tgagtttggt agtaggtata agcctgagta attacaggat atagacctac
    18061 tcctaaacat agcaacatcc caatttttaa gatgatcaac ttgatattct tctttttcat
    18121 gctcatacct acttttcaca cactttttaa aaagaaaccc tagagccaaa aacactctag
    18181 ggaattttat ttcattaagc tttgtgttgt tctcgtttgt agacaacata tagccctgtt
    18241 cctgccacac ctgcaaccac tagaaatact actgttccaa ttccacctgt acgaactgtt
    18301 tcaggtgttt taaggttctt gatgtctgtt acttcgctag aagcatcatc attcgatacc
    18361 acaaatggaa catcatttct agttggtgta tatcctgaag gagcaacaac ttcttcaaga
    18421 gcataatcat tgattttttt atctgtgatt gttggattac cttgtttatc aaaatctaca
    18481 tcataggtat attgcaagcc ttcaatttgg aacttaccat ctgatccgga aacgaattca
    18541 gtagctttag atttatctgc aatccaagta acagatttcg ttgttggatc ttgttttagg
    18601 taagtaactt tattcggatc aattttgttc ttcactacaa attttgctcc actcaatgct
    18661 ttgcttgtat ctccatctgt tttaatgaat tggtgatcac caatgattgt ataagcgtga
    18721 tcaactggtg tttcgtcttc gggttcatat ccattgttgt agatcgttga aacatcattc
    18781 ttaagtggtg tatccatttt agctttacta ttagtatgag cgttcatcaa aattgtaaag
    18841 aagcgatccc ctgcatcaaa ttgtttctga agcttatcca tacctgattc agtaaagaca
    18901 tagtttgtcg tttgtccgtc acgttcgata ctgtaatcag tatctaaagt cattccttcg
    18961 atcacttctg atgaatcata agttaactct gcacctagaa catctttgac aacatatttt
    19021 tcgtaattac caatattacc aggaattgat ggtttcaatg tatattgaac atcttcgcca
    19081 gtatcaacgg tttctttatc aattacctta gtaattacag gtcgtttgta gttggtaaca
    19141 tcaagaacta ctttagcagt ctccccacgt ttaacgctaa atttgaattt tttaccatct
    19201 agtaaatagg ttgttttatt agcatctgtt cccaaatcgg tttctaggaa ataatagtca
    19261 cctaattcca aaccatctac agttaattta cctgtgctgt ctgttttata agttccaaca
    19321 acctgatcag atccatcatc ttttcgcaat tcaaaaacag ttccggcaag agcctttcca
    19381 tcttcgtctt ttttatcaag ctctgctgag tttaattgga aatagttttt aggatagaca
    19441 tgtacatcat aattaaagta ttgatcatct gatccgttta gttcaggtac gttaacaatc
    19501 ataggatacg cttcttcaac tacacctttg actgttcctg tttcaacaat caaatacaag
    19561 ttatctgtta aatcgtctgt atttacttgt ataggtatgt ctatattccc ttgtgaatca
    19621 gtcttcattc tacttacttc actgtatttt ttgtttagta ataatcgtgc tttagcatca
    19681 tcaatatgtt gaccttttgt agtatcacta tccgtccatc ccaaggattt agcttcatct
    19741 ttagtaagtt tcacataaga gaactcaacg ccttcaagag gttttacacc atttggtaaa
    19801 gctatttctt tccctttgtt atcaatatct gagacagggt tcccatcccc attagtattt
    19861 gttactttat ggatatgaat cgttccagtt ccttgataat tatagttttg ttgtgcatat
    19921 gctacttgcc cccctagtcc aaggctagaa gagattgagc ttgcgcccaa tcccactcct
    19981 agcaaagtac caaatagcat taaatttgaa aaaatttttt ttgatttcat acgtcagcct
    20041 tcttttttca tatttacttc ttttccatta acactttttt attttgcttt gtgctgttct
    20101 cgataataca gtagcaccat actcaatcct gcaattagaa atacaagaag gaaggctgat
    20161 gtaccgattc cgcctgttct tactgtttca ggtacaaggt gattaattac tgtatattca
    20221 aaggtttgtc catcgtcagc aacggtgatg ccttctttag accatttccc tgtataacca
    20281 ttagggtttt gtgtttcttc gattttgtac gttttgttgg caacaatatt aaatgttgcc
    20341 aagccattgc tgtccgtttt ttgtacaact tttacacctt tgtcgtctgt caaagtgaat
    20401 tctgcgtttg ctaatgcttt cccttgatca tccactttat gaactttgat cacacctttt
    20461 ttcaaagtgt ttttagcagt atattcaaag acttgtccat catctttgac ggtaattcct
    20521 tcttgtttga atgcgcctgt gtaacctgtt ggtacttttg tttcttctaa gttataagtt
    20581 ttgttcgcaa taatgttgaa cgtagccaga ccagttgcat ccgtcttttt aacttctttt
    20641 acaccttttt catccgttaa ggtgaattct gcatctgcta aaggttttcc atcttgatcg
    20701 actttatgaa cttttactac accttttttc aaattatttg tagctgtata ttcaaaagtt
    20761 tgcccatcgt ctttaacggt gataccctct tgcttaaatg cacctgtgta acctactggt
    20821 actccggttt cttctaggct atacgtcttg tttgctacaa tattgaagct tgcaagtcca
    20881 ttttcatctg ttttttctac ttgtgttgca cctttttcat cggttaaagt gaactctgca
    20941 tttgccaaag gttttccatc ttgatcgact ttatgaactt ttactaaacc ttttttcaaa
    21001 gtgtttgtag ctgtatattc aaaagtttgt ccatcatctt taacggtaat tccttcttgc
    21061 ttgaatacgc ctgtataacc agttggtact ccggtctctt caaggctgta ggtcttgttt
    21121 gctacaatat cgaagcttgc aagtccgttt tcatctgttt tttctgcttg tgtttgggat
    21181 gaatcatccg tcaaggtaaa ttcagcatta gctaatggtt ttccatcttg gtcaaccttt
    21241 ttaactttta ctttaccttt tttaattgtg ttcgtagcag tgtaactaaa ttcttgtcca
    21301 tcggtattaa cagtaatacc atccttttta aatgaacctt gataaccttc aggaactttt
    21361 gtttcttcta agctgtatgt taagccttgt tgcaaatcaa acgtagctaa cccatcatct
    21421 ccggttgtct taacagattt agcattgtta ttgtcagtta gagtaaactc cgctcctttt
    21481 aaagcatttc catcttgatc aactttctta actgttacct gaccaacagc tcttgtccat
    21541 ttagcactca aagatttaga gtcctttgtt tctgaagtag tgatcataac tacggcatct
    21601 tgatacacac ctcgtccatc aaaagtaaaa ggattggttg tgctaacatt agcagtacct
    21661 ttaaatgaca aagtaccact tggtgtagtc acaggtactt taatagtaaa acttgaattt
    21721 aatttcacag tgttgttagt aatttcttta ccatctgcat cataaatctt cataccagct
    21781 ggttttgctg atgtaaaagt gagcttcgca ttaccagtct tatttgatgc tgttttatat
    21841 gtgaaagtgt gatattttcc ttcgtcagct gtcttagaag ctgtgataga aaactcagtg
    21901 ttgggcgtat cttttccatt cttagcatag tcataaattt tttcaaatgc tttttttaca
    21961 cgagctgttt ctgcggcggt atggtttgga tgtgaccata caatctgtga aactttaaag
    22021 tttccggcta aaacccatga aactaattgt gttgcatacc atgcttctgt atcatttcct
    22081 gcacccagtt cctttgctgt ttttgatgga aaaccacctt taaacatacg atagaactca
    22141 tcactgccag ctcccttgta cttcaagctt ccggctccac ttcctgttgg ggatggcaat
    22201 tctgaatcca tacaatatcc aatatttcca tgagaatctt taaattgact tgaaatcatc
    22261 cattcatttg gatgattcgg catattaacc ctaatataac cgtctgtttt tacgccagtt
    22321 tctataaatt ttgcacttgt cggttttgtg acatctgctt cagctcttat tgctgaaaaa
    22381 ggcattataa gcgtagataa catcattact aaagtcgcaa aacaataaat tatttttgat
    22441 tttaaaatta tcgttttttc atgcttcatc tctcgttact ccttctttat accagttagg
    22501 cgaagaaaat gagccacgat atgtcggtgt ggtaatgacc ttcgcgccca ttcctaagtt
    22561 aaaatcacca cacctattaa tcattttttt cgttgaaagc aagctgtttc aacgctctag
    22621 tattcatagc atcacccctt ttagttctac ccaccatgag caacaagttt tctaagtagt
    22681 taagcaagga caaataaaga ctatataact acttagtata taaacgatat cttttattaa
    22741 cgtaccgaaa ccgctaattg agatacgtta tatgctgttt caaatgatcc tgcattaatc
    22801 caacttgccc caaacacagg atcgacaaca tggtaaaaac cgtctttaaa tccatcaacg
    22861 gctactacat gtcgattcca aatagcatcg ccccaaaaca ttggtttatg ttgagcaggt
    22921 tcaaaggcat aagttaccca cgctactaca ggatttccat ttacaatctc atcttttaat
    22981 ccttgtaccg atgaaccaga aatatctaca acatttccgc cattagcaac accccatgaa
    23041 actacaggag ccggattcat accttgataa gttccatcca cattgtgtct ccattcacca
    23101 gaaaaaccat tatttggatt attgtcagga gatagtggca ttgatttaac aaaagtcatt
    23161 aaatcttgat ttgttgcaac acctttataa tgtaacgctt ctagcaaaga tgttccttcg
    23221 caaagcattg tgttaccttg actaataaat ggaacgccta gcacaacatt agttggttgt
    23281 tcgggtttac ttggtgaagt agaactgtca gtttcatcac tcgaacctgt ttgtgattga
    23341 tcactagaag atgtactggt tgattcattt gcatcatttg atgttgattg tgagttattt
    23401 gttgatgttc cagtatcagc ttccgtagtg ctactttcac ttgttccctg tgatgcttct
    23461 ttctcacttg tagaattatt tgtattagat gaacttgctc catcaacact tgaagcactt
    23521 gtttctgtct tatcagaagt gtttgctgtt ggttccgatt cttttgtagt ctcggatttt
    23581 ttgttctctt gctccgtatt ttcaatagga tcaggtttat ctttttgaac agtttgacta
    23641 actacttcgc catctgcttc cttaactgtt aatgtatctt tactgatgtt gaaagttcgt
    23701 ccaatcggga tagtccgttg ttctcctttt gccaaatcaa cattgttcaa ttcggcaaac
    23761 tcagcaacag tagtcttgta acctaagctt ttaagcttct ctacagttga ccaaatagta
    23821 tctccttttt tgaacgcata acttgattgt cctgttgtaa tttggatttg atccggtgtg
    23881 tttgcagtcc attcatcagc atgtgaggtt actggtactg ataaccccgc aagtacagct
    23941 gatgccaata aaaccatacc aagcgaattt ctcttcatat tcattccttc tttttgtttt
    24001 tattttctgt ttgtgatcgc aatgcttcta ttccttcttc cgttataata taggttttgt
    24061 cacccacttt cttgaacgaa cctttaggca aacgatttgg ataatagttg attatgtttg
    24121 taacataatt tctaccttta cccaaaatca aacttgcttc ccttgcggta tacaagttgt
    24181 atttgtctag gttcaatttc tttttgtttg cgatttagac ctaccccttt cgcaaaattt
    24241 attgtataat aatagtacca ttgcactgtc ataattgcaa tattttttgg ggtttatctt
    24301 catttaatag cctaaaaagg cttgttagat aaggaatatc taactaatca aaacaaaaaa
    24361 ggatgttaag aaaaaatgaa caaaaaaagg aaattatcag tattaattac acttgtttct
    24421 atattgacta ttcttagcgt tatcttgtcg ctgaaaatat tcaatcaaat aaacacaagc
    24481 tcaaatgcca aagatggaat agtcgtagaa aatacctcta attctaaaga aactggtact
    24541 actacaaaaa aatacaaatc tgctgagatc actacgaaaa attatttaat aaagactgtt
    24601 tattttgatg aacgaaaaac agcaattctc aaagatgagg aaggatcaga attaaagcta
    24661 cctataacgg tatccgataa gttcaatgga acgttctcct tacaaaccgc tgaaggatca
    24721 cctgacaatc tcaaagttgg gcaaacaatc attcttggta aaaacgacga actgtattca
    24781 tttgtaaaat aaaaaaatgg agcaaaggct agtcaagccc ttgctccatt ttccattctt
    24841 caagaggtgt agctatttca acaccaaagt ttaaatactg tggatgctgt agatacatga
    24901 tatccattct attttcgata aactctttta acgttgagta gatgtatttt tctaatgcta
    24961 tatctgccca actaccataa tcaagtttat tcgtgatctt gacgtttatt tcaatttgag
    25021 aaacatcaat attttgaaca tcaggaaact tattcagtct tagctcttct ctaaccgctt
    25081 ctactagcgg ttcatattgt ccgcctagtt cgctaattgt tgaaactatt tcatctgaat
    25141 tccaacgatc ttccaatacc tttgctacat tttctttagg cggttgtctt tctataaatt
    25201 cttcaggtgt ttcatcaaac tctactctaa agttcaattt attttgattg ttagcataca
    25261 tataatcatc tctgtttgat tcaaaaaagt tacgaattcc tgtgtctgat ttatcactta
    25321 actccttatt tgctaaagta gcccaaaaat cccaagttcc tttattttca gtatacaaag
    25381 taaaattaat gtttatatag tttgcagttt caggataccc ttgctctcta agagcatctt
    25441 taacaatcac tgctaagtca gtttcaaaat tctccataaa aaattcacta aattcttttg
    25501 gattccacgt ttcttctaat aacttttcta atttatgatc tgccattatt attctccccc
    25561 actttacttt caatcttata tctaaaactg cttaaaatta agagctatac cttatcataa
    25621 aaggtatttt atgctttatt taagtctaca attctatatt acaattatca tctagaccat
    25681 tttcttatgt caaataaacc atatatattg tctttaatag ttttatttga ctttttaaga
    25741 aagtatttac ttttgacttt ttttacgttt tacaacatat acgtattgta atgttcagct
    25801 caatttatta taatctaaat gaattgatta ataaaaattc tgaggttcgg gttttttatc
    25861 aattcttttc tgtttgtgtt tgtgatgaaa caatcctttt tcggtaggtt ttgttatcat
    25921 cgtcagcaca aagagctaac gttggtaccg ttagctcttt ttttatttta ctctgctctt
    25981 acatagctat ctaaatcctc caaataaaac aattgatttt ctcctatgct tgttactcca
    26041 cgccaaattg ttgttgttgc tgttgttgga gtatttcttg tctgtgtaat caattcaacc
    26101 attttacctt tttgatttgt tgtatagtaa tcagcagtat agctagatat tggactatta
    26161 ccagtgccta ccatcgtgcc agaaatatca acaggactag actttactat ctgaggaaat
    26221 tctttttgta tttccttcat attcttcgta tatttttccc atgaattcca gttgtaaaat
    26281 aaattaaaga atttcctact ttgttcctta atttcagcat ttcccaattc tttgtattga
    26341 gcttcctgca tagctttcac tttctggtta ttcttgacta cttcgatttg tttactttta
    26401 aggtcttcca attctttgac attattatca taagcatttt tcttttgaaa tagtaccaca
    26461 caacaaagga tcacaattat ggaaagtatt ccgatcgcct ttttagcagt agtgatttca
    26521 tgattttgca taaaaagcac ccccagtcac tttcttatca ttatttagtg tgatggttaa
    26581 tgtggtatca tacacttttt ttccattgta ttgaacttca aaatcggtca atgcttcata
    26641 caacccacta ctagatgtct taattccaaa gtttgttagc ttaaaagtaa aaggcttata
    26701 gtactcgatt ttttctttct cactactctt atcagtaatt ggtggtttac ctgttacaat
    26761 aaatagtttt ctcaaaaatt cttcacctga ttgatctgca aacttatttt gaactgatcc
    26821 attcaacatt tcttgaatat cattttctaa atctttccgt aatccatcca cctcatttgg
    26881 tttaacctct ttaaagaatg tcagcttatc ttcaatatgc acactgtgtt tttcagcttc
    26941 tatgtcctga ttctgcttat tgaagaatag gattccaaca agcagtgcta ataacatacc
    27001 agaaagcaaa gaaatgataa ttgtatcttt cactttacta ttcatctata tcgtccttca
    27061 ttccaattta tttttcgatt tcaaatttag cttttcctac accgctaaag aaatgcacat
    27121 tatctgatcc gtccactcca tcaatcaacg ttaccgaaac tccccttgtt ggagcttggg
    27181 ttggtggaac attaaagtta gcacatagaa atgatccatc ttcaaacacc gctataacta
    27241 caccagtatg ccctgcatct ccaacagccc ataaccatcc atccgaagca ctaaacccat
    27301 aacctacgat tggtttgttc gttatttttg ctcctgccga tttgtagctt tcccatacat
    27361 aaccaccatt tccagtagtc ggttgattcc catcgtataa ttggctcata taagcccacg
    27421 tcaactctgt acactgacct tgatatattc cgttaaaagg tgaagttgac caatctggtt
    27481 ctttgaattt tggtagcgtg atcgctttcc catatttttt caaagcttct tcataagtca
    27541 tattcgctat tacttgacct tttttaccgt taatttttcc ttctttccca attgatccag
    27601 aaccagaatt agcgtcatcc gtagttgcac aggcatcttc tactgttcct gatgctgaac
    27661 ttgatgaatt attcgatcca tctccggtac ttgaacctcc ggatatttta ttgatcttac
    27721 tttcatcttt tgcaccgtcc atacccttgc ttttcatgta cttccagatt tcttttgcat
    27781 tttcaccacg tacagctatt acagctgatt cggaatcagc tgaaatttcc cagtttttat
    27841 gaaaagttac tgcattttct acgacatcat cagaagcatt taaagcataa tcttttaata
    27901 ttcctacgaa tcccccatca cctttgaaca taaagtccaa ttgggcttct gtagtccacc
    27961 aagaaccgcc attatttttc ttagaccaat caactaatgc tgtatgtcgc ccagctgtcc
    28021 attgaccata gccaataccc atcagaccat cagtaaattg tttgatgaag tcaacttctc
    28081 tctgtccatc tccgtaatac ccttctactg ctcgaggatc aatacctgat tcttgtttcc
    28141 agttacctaa aatacctgca atactagcac ctgataagcc atattctcca ttcatgtatt
    28201 tgtaaatatc ttcaatattt ttggctacat cacctgttac agcgccactt ccagtatcgt
    28261 ttccatcgct atctgttcct gacccactac cttcagtagt acagttaaat tgtgcatcat
    28321 aagtagctat cccatcagca tgtatcactt gcggatttat tgtgattaca ctcattgcaa
    28381 tccctgtaaa ttgcaccatt aacataagca atgtggcaat ctttctctta gattttttca
    28441 ataactacgc ccccaaaaag tgtacttttt tatgttatta tgataatata ataacataaa
    28501 ttaatagaaa ggaaaagcta ataaatgact gataaaacaa gtgatttacc taaactagct
    28561 ccaaaaacat ctcgagtaaa gagcaaaaaa gatggaaaaa caaaaaatgc tgtaaagaaa
    28621 aagtcagtaa aagaaacatc ctcgttacta cttgatattc caatgagttc ttttgatgac
    28681 aatacggacg aaacttctgt taaaattgca actcacgttg gaatgaacaa tcaaaatgat
    28741 tctttttaca acttgttaaa cagcctaaga gagttggaag ataaaaaaaa tcaggtaatc
    28801 gcatcaaaag ctcctgatct cacaaccgat ttggatgctg aaattatcca aatcaaacaa
    28861 gatgagcgat cagttaaatc gctactgaaa acctactttg atggttttga taaagaacta
    28921 gctccttata gccaagcaat cctaactaaa ccaatacaag ctccacatat ttcaatttcc
    28981 ctacaaaaaa agagtgatga ttaaacaatc attactcttt tttagatttc tggtaagcgc
    29041 tgatcgcaaa aaccatcaac aatattgatt caaaaaatat gttcattcgt gtctcttttt
    29101 tccattatag atttcccact attccattaa atcgaaagtc acaccgatta ctacaaagat
    29161 taacgtgacc acattcaaaa acattaaaag atatgctgat aatctcatca tttttttagt
    29221 tcacttactg gtaatctaaa catttgaacg attgcactgg aaataccata attagcaatg
    29281 acaaacaaaa aatacgcaat aatttcactt acacctagat agatcagtaa aataaataag
    29341 tcacttaaca ttgttagttt cctcccagta tatgattttc atttttggga agtcttttat
    29401 aatccaattc ctcaaaaaaa ggaaccatag tgtcactaat ataggtttta gtttcaggta
    29461 ccgccaaaat tccccaatca agaatttctt cccatgatac atcatcaaat tctaaaatat
    29521 tatgatcaac tgacctatta ccaagttcat atccaccaaa gatcaccata ttatcaatca
    29581 tgtatagaat ttcatcaggc gaaccatgag ttaatgtttc gtcctcttca agcagttcgt
    29641 ttaatctttg tttgtattcc tctcttttca tacttttatc ccttctgact catttttttg
    29701 aattttaaca tttttaaccc aagcatgact atctttacat gctattaatt tttatctcca
    29761 ttttgatatt tctgtttttt tctactcacc aatcaaccgt aaatcctcaa tattctcacc
    29821 ttcaagcgaa tatgaatata cttcgccgta aatattttct ataactacga cttcttcttc
    29881 aaagtctatg gactgcacat caaaccattc tcctccgcca aattcgtcta tgattagtac
    29941 ctgcaatatt ttatttactg ccatttcaat ttccccttat accattctat gtcttccaaa
    30001 ctatttttct tctttccata ccaaggtttc acgtatctca aaattttctt taaataagtg
    30061 ttccggtact tttataatta actcttttcc tacttttatc agatagtctt tttcacctaa
    30121 tgagatttga ccagtcggta actgtataga aactctttta gttttattaa attttttagt
    30181 tttcaataca gtatacggtc tacagaattt ctctaagcgt tcaaatcttt tactatcgta
    30241 ttggaaataa gctttaggaa cagataaagt acaaaaacta tcggtaacag cacttatgtc
    30301 ttttttagaa attatcccaa ctttagaact tctaaggaaa gttgctaatt tcttatatcc
    30361 accatgactt gtttcaatat agatgctatt gtattggctg tcgtctatct catttattgt
    30421 ttcaaccttt ttcctgacag gtgtttcaac gagttctcga acctcttctt cactgtacgc
    30481 taatacaatt aactcttccc catttaccat ctttagaaca tacgcttgct tcttttttct
    30541 tggcttattt tgagattcaa cataaccaga catggaatct ttatacttcc aagcatgtac
    30601 ttttttctct aatttctgta tctctttttt cagctgtaga tattcagaca ttttttcatt
    30661 gtaacgttcg caatataaac aatattcatc ttttccaaaa tcatgatcaa gtccttcttc
    30721 aatatgttta ttcaacaaac cggaaaaata ctgatcatac tgcttctttc gtaacttcag
    30781 ctctcgtaaa tcttcagaca tttcattttt cctttccaat tattggtgcc atttcacaat
    30841 ttgggattga ctaaacacca taattaattt gtaagctaac acaattacaa ctgttggtaa
    30901 ttgtgttagt ctccatcaac ttgtctggtg gcttttttta ttgcacaaat ttcatagctc
    30961 tcaaaaagcg cttggcttga aaaggtgtta ttctacgaac cttattcgcc aatttccaat
    31021 ctgataaagc aatttgccat tcgtgcattt caaaatccgg catgatttct ttgatatact
    31081 gtagctcttt cttttctctt tcttttaaga aacggctcat cgagtttaac attggaacta
    31141 aggatgcgta ggtacttgaa taacttccaa tgcgtttcgt agtaattaca taatcaataa
    31201 aaacactatt aagaaaggtc aagtttataa actctgattc atacactcta aaatttgcag
    31261 ttaatcgctt cgccttgtca ccccaatagt cacttttgtt gtaggctttt tcccctcgaa
    31321 tatagcactc tgtttctctt tcgtaataat agtcatactt ttttcatcat caaatctgag
    31381 agtttttgat tatctttttc actgtaaaat aatctactcg ttaaactttt aggataatct
    31441 ttgatagaat atgcatccca aacaattctt tgaacatatt cacgatctat attttctctg
    31501 acttccccag tccaaaaatg ttgaccataa tggcatcttt ctattacatt gttagcagaa
    31561 acttcaaaat aggattgttc cctttgtatc ctcataccaa tcatcatagc gcaggaaata
    31621 actattaata acaatcctgt ttttaatcta ttattccaca tgcagtttcc acatccttat
    31681 cttgataaaa atcctcttga ccctctccaa ttactgtttt aaatataacc accaaaacaa
    31741 gatcatgcta agaaatccaa gagtatataa gatgatacat tctttgttaa ttatccaaaa
    31801 aactctgatt tctttgagct tttcacgcat taggaaacac cttgttatat cttttttgta
    31861 tttctttcaa ttgtttttta aaactcataa acaactgttc atgatctggt ctaagcgtta
    31921 gaatatctaa attatttatc ttttttaatt gtgtaataaa atctattttg gattttcttt
    31981 caatatcaaa accgacaata atctttcctg ttggatcaac gcatttcact tgaataactt
    32041 tgtcattttg cgatagctct aatattgatg atttttcttt tgcctcttcc aaaagatgtt
    32101 ctaacacttc gttaggtgtt ccatgatagt aataaatcat ggtcttctcg aaaattttta
    32161 tcggatcaac accatattct tttccgattc gataaaaaaa tttcattgga atttcttccg
    32221 gatttctgtt cctgcttgac cagttagaga tggtttgata atttgcaaaa tggattcgtt
    32281 ccgctaatct ctgaactgtg gtctctaaat cttcttctat taattgtttt acagcactaa
    32341 tgttttgtga catttgcttt ctatcccttc aaattcgttg cattatcaat tctaagattt
    32401 catgttttag tgcatttcta tctacatttt gcttttttaa ctctgcacca taatatcttc
    32461 gcaatccctt atccaagcat acaattcctt gatctaatag atcatattcc gctttttcaa
    32521 accttcgctt tgcctgctca acaagcaaaa tgatattgtg atgtatct
//
LOCUS       DBBGSP010000031        31560 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000031 DBBGSP010000000
VERSION     DBBGSP010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.031"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..524
                     /locus_tag="ACIZE9_001708"
     CDS             <1..524
                     /locus_tag="ACIZE9_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093571.1"
                     /translation="DVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDVRENVQN
                     STSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENVQKDSGE
                     MKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNELFRDTL
                     NDPNPLFDNLLKK"
     gene            539..757
                     /locus_tag="ACIZE9_001709"
     CDS             539..757
                     /locus_tag="ACIZE9_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093572.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
     gene            2276..2590
                     /locus_tag="ACIZE9_001710"
     CDS             2276..2590
                     /locus_tag="ACIZE9_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093573.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(2643..3416)
                     /locus_tag="ACIZE9_001711"
     CDS             complement(2643..3416)
                     /locus_tag="ACIZE9_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093574.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            3521..3766
                     /locus_tag="ACIZE9_001712"
     CDS             3521..3766
                     /locus_tag="ACIZE9_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6093575.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            3922..4773
                     /locus_tag="ACIZE9_001713"
     CDS             3922..4773
                     /locus_tag="ACIZE9_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HGC6093576.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            4806..5483
                     /locus_tag="ACIZE9_001714"
     CDS             4806..5483
                     /locus_tag="ACIZE9_001714"
                     /inference="COORDINATES: protein motif:HMM:NF024685.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HGC6093577.1"
                     /translation="MDKKVLIKRFSEAIEKGNAAIFAGAGLSMSQGYVSWPELLNDPA
                     TEIGLDSKKETDLVTLAQYYKNENGGSRGILNQILMDNFGEELEISENHRILASLPIE
                     TYWTTNYDHLIEKSIREAYKNPQVKKNYTQLATTNPNVDTIVYKMHGDIDDVSSTVIT
                     RDDYEKYDDSYALFKETLKGDLLTKTFLFLGFSFTDPNLERILSDIRWVLRENQRPHY
                     CIMRKIL"
     gene            5971..6936
                     /locus_tag="ACIZE9_001715"
     CDS             5971..6936
                     /locus_tag="ACIZE9_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6017 domain-containing protein"
                     /protein_id="HGC6093578.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            6958..7170
                     /locus_tag="ACIZE9_001716"
     CDS             6958..7170
                     /locus_tag="ACIZE9_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HGC6093579.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            7245..7721
                     /locus_tag="ACIZE9_001717"
     CDS             7245..7721
                     /locus_tag="ACIZE9_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HGC6093580.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            7718..9526
                     /locus_tag="ACIZE9_001718"
     CDS             7718..9526
                     /locus_tag="ACIZE9_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HGC6093581.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            9603..9818
                     /locus_tag="ACIZE9_001719"
     CDS             9603..9818
                     /locus_tag="ACIZE9_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family mobile element protein"
                     /protein_id="HGC6093582.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            9910..10773
                     /locus_tag="ACIZE9_001720"
     CDS             9910..10773
                     /locus_tag="ACIZE9_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB6/TrbL-like conjugal transfer protein,
                     CD1112 family"
                     /protein_id="HGC6093583.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            10810..11346
                     /locus_tag="ACIZE9_001721"
     CDS             10810..11346
                     /locus_tag="ACIZE9_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MT-A70 family methyltransferase"
                     /protein_id="HGC6093584.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            11360..11782
                     /locus_tag="ACIZE9_001722"
     CDS             11360..11782
                     /locus_tag="ACIZE9_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HGC6093585.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            11712..14111
                     /locus_tag="ACIZE9_001723"
     CDS             11712..14111
                     /locus_tag="ACIZE9_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4-like conjugal transfer ATPase, CD1110
                     family"
                     /protein_id="HGC6093586.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            14143..16134
                     /locus_tag="ACIZE9_001724"
     CDS             14143..16134
                     /locus_tag="ACIZE9_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HGC6093587.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            16157..16408
                     /locus_tag="ACIZE9_001725"
     CDS             16157..16408
                     /locus_tag="ACIZE9_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HGC6093588.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            16398..17627
                     /locus_tag="ACIZE9_001726"
     CDS             16398..17627
                     /locus_tag="ACIZE9_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1107 family mobile element protein"
                     /protein_id="HGC6093589.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            17624..19705
                     /locus_tag="ACIZE9_001727"
     CDS             17624..19705
                     /locus_tag="ACIZE9_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HGC6093590.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            19854..23774
                     /locus_tag="ACIZE9_001728"
     CDS             19854..23774
                     /locus_tag="ACIZE9_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YodL domain-containing protein"
                     /protein_id="HGC6093591.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            23775..24719
                     /locus_tag="ACIZE9_001729"
     CDS             23775..24719
                     /locus_tag="ACIZE9_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093592.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            24723..24926
                     /locus_tag="ACIZE9_001730"
     CDS             24723..24926
                     /locus_tag="ACIZE9_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HGC6093593.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(25226..25462)
                     /locus_tag="ACIZE9_001731"
     CDS             complement(25226..25462)
                     /locus_tag="ACIZE9_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093594.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(25645..26016)
                     /locus_tag="ACIZE9_001732"
     CDS             complement(25645..26016)
                     /locus_tag="ACIZE9_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HGC6093595.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            complement(26013..27341)
                     /locus_tag="ACIZE9_001733"
     CDS             complement(26013..27341)
                     /locus_tag="ACIZE9_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HGC6093596.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(27302..27631)
                     /gene="mobC"
                     /locus_tag="ACIZE9_001734"
     CDS             complement(27302..27631)
                     /gene="mobC"
                     /locus_tag="ACIZE9_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HGC6093597.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(27889..28259)
                     /locus_tag="ACIZE9_001735"
                     /pseudo
     CDS             complement(27889..28259)
                     /locus_tag="ACIZE9_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            28404..28589
                     /locus_tag="ACIZE9_001736"
     CDS             28404..28589
                     /locus_tag="ACIZE9_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGC6093598.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            28768..28914
                     /locus_tag="ACIZE9_001737"
     CDS             28768..28914
                     /locus_tag="ACIZE9_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093599.1"
                     /translation="MTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVSRHWITAG
                     LMRL"
     gene            29532..30191
                     /gene="vanR-B"
                     /locus_tag="ACIZE9_001738"
     CDS             29532..30191
                     /gene="vanR-B"
                     /locus_tag="ACIZE9_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-B"
                     /protein_id="HGC6093600.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALLDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            30194..31537
                     /gene="vanS-B"
                     /locus_tag="ACIZE9_001739"
     CDS             30194..31537
                     /gene="vanS-B"
                     /locus_tag="ACIZE9_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-B"
                     /protein_id="HGC6093601.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
BASE COUNT         8573 a         7661 c         8093 g         7233 t
ORIGIN      
        1 tagatgtccg agaaaatatt caaggttcat tgaatggtca tgtcggacgg aatgttgatg
       61 taagagagaa tttacaaagc tcttcaaatg gtcaaggtac taagacaatt gatgttcgag
      121 aaaatgtaca aaattctaca agtagtcaag ggtttaaatc aatggatgta agagagaatg
      181 tacaaaattc tacaagtagt caagggttta aatcaatgga tgtaagagag aatgtacaaa
      241 gttctacaag tagtcaagga ttcaaaacag tagatgttcg ggagaacgtt caaaaagata
      301 gtggagaaat gaaagaaaaa acacaaaaaa tcaatatcgt tgaagacaga aagtcagcga
      361 aaaaatttga ttcaaatcat gaaacagtga ttattgatag tgaaatccgt gaaaatgata
      421 agggatcaaa accaagacga agatttacct atgaagacaa cgagttattc agagatacac
      481 ttaatgatcc taatccgctt ttcgataatc tattaaaaaa ataaaagggg gaattgtcat
      541 gaaattaatt ctaaagatta gtacgcatga tttcttagaa cttgacgaat tatgtgaatc
      601 agtaaagaac gcaacaaatg aaaaaatcac ggtcactaat tatattgaac tgatgattca
      661 agaagaatta aagatgaaac atgagataaa aaacaacttg aaatattgtt atctagaaaa
      721 aagtgaagag ataatccatg aattaaatgg cttttaaaaa ttgtatttga catgaattta
      781 cgacaaggaa ttagtgggga ttaagcgatt attctcttcc actttagaga aataatgggt
      841 taaaaagcca gaatacgtag agcaatattg acaacctata aaggagctat tgttgaaaat
      901 tgaagtaaca aaaagataaa gagaggttta catctatcag attaaaagtg atagtacacc
      961 catgaaacct gcaaaagagt tgaacctaat gtatatcggt ttaactcttt ttatttgcaa
     1021 attaaaaaaa tatcaccgaa gtgacgaatg aaactatgac caaattaagc aagaaaatat
     1081 atcttgcaaa taaagtagta taaaaagata ttgataaagc caatcaaaac tttgaatttc
     1141 aaacgttaga taatcaaaca gatacaaaaa atgaaatcag ttctacgcgt acgattatta
     1201 aaaataataa attttcacta gaagaaaatg gaaataaaat caaataatta ggaagaaaaa
     1261 acaaagcaat tagaaaagcc tgcaagcaaa tttgagtaat cgagatccaa tttttttaag
     1321 gaagtttaac aaaaatatgt aattctatta tcactattaa agagaaagtt ggagcggaat
     1381 ataaagaaaa gagaaaagta attaaacgca aaaaaatgta gaacttaaaa aatataaaga
     1441 ggaacaaccg ttaaaattag gaatgatgtt gtgtaaacat tataattgct atgatataaa
     1501 tgaagtgtta aagaaagcaa atttaaacca attttgtgaa cagaaaagcc ttagtcacta
     1561 tgaccaaaac tacggacgaa actatgacca aaagtaggta ctaaattatg accgaaaata
     1621 ggtccaaaat ggattttttt atgatatcaa aaattatgaa atgattttga aagaaaacca
     1681 gttggcacag ccaacttagc caccttcctg taggaaggtg ctatcagttt tcccttatgc
     1741 tcttttcttt cttttttgtt tcatatgtca aatgccattt tgaaatgtac catcttaaga
     1801 aatttatcct taaaaacaat tgcgttattg gataaaaaga tgctacatta tcttaaaaaa
     1861 ggaatcaaat atgatgaatt tagtggctag catatcgtgt gattaagata ctttatagtg
     1921 taagttgaag gagaaaaaat atttaaaata tacttcccat ttcagtggga agtaaaatta
     1981 atcttgttgt ttctactagt aatgtatctt tttggaaact atgtaacgat gtaaacaaga
     2041 tttttttcag aagaaaaaac gataaaagtt gtgataaacg atttaaaaaa taggagaaaa
     2101 tatatcaagc gcatggtatg aaacgcacat ttaaaaagat tcgactaact aaaaaaataa
     2161 gtttacaaag cattgttgtg tattacaagt gatctataca ctgaaaaatg atagagaaaa
     2221 tctgatacgt ccgcaacaat ggacaattga aaatgaaagt gaggaaattg gaagaatggc
     2281 tgatgaaaat aaagttgttc cgcttgaaac actagtgata aataaggaag agtttgagca
     2341 actttttctt gatttttttg ttcaatatga caggatttat gattttagtt cgtcactaga
     2401 tttatttgaa ttagaggcag aaataataga aaacagtcga gaggagaatg gtaaaatcat
     2461 catttcagta gaaaaattca atgaattatt ctcagaaaca tttgaaatag atacagatta
     2521 ttatcaacca caagaagttt tccaatcatt tagaaatcag attattcgct caggtaagac
     2581 cgtaaactga aaaacaataa aagaaacgtt gaaagaataa ttattccttc aacgtttctt
     2641 ttttagaatg ttttaatgac caaagcagtt tcattgtcag gcttaggtaa ttcatgaaat
     2701 cccgtattta tagtgctcaa ttgatcaact aaccatgttt tactttttga attgtagata
     2761 aatctaaaat taatatcgtt attatcgtgt tgaaggggcg tctccaaata atctgctgta
     2821 tattcatagt caacgtaacc tgctaataca aaagagagta tccctttatt taatgttaga
     2881 tttaatggat aatcatacga ctttattttt ttcaacttca tattgtacat atcttcagcc
     2941 ataaaagttg agttcgtgat ttcatcttgg gtctcattaa aaaagttatc cgaataatcg
     3001 cttatttttg aaaagtcttt attggcacca gcctcaaaaa attgttcaac tttttcagta
     3061 taaagttgtg ctaacgctcc tttttcaata ttaactttaa tattttcatg tctatcaatt
     3121 tgtgtgctgt tcagtaaggg aagatcagct tttagtttta tatcgtcttg atttctttca
     3181 atttcaattg gcaaaatctt ttcagtagat tcagtttctg ataaaggaac atctagtttt
     3241 ttatcatgat aataagcttc aaatccatct ggaaccggaa aaaaatgtat tgggtaattc
     3301 ttttctgagg ttgttgtact agtttccgta cttgtagaac ttgtgtcaga agtggtacac
     3361 ccgcttatag ttccgatgag taaagcgcaa gttagaatga ttgcaaattt cttcaaaaaa
     3421 attcctcctt aaaattgaat atggactaat actagtccca ttgtagcata ccgaatcttt
     3481 aagattaata agaaaaagga ctaattttag tccaaaaggt gtgctattct tgaaagagga
     3541 aaaaattatt gataaagaaa atgtaatcgg tagcaatatt agacgagtcc gattagaaaa
     3601 aggaattggt caaaccgagc tgattagaga cctacagctt cgtaaaattg ctataactag
     3661 ggaaacgttg gttaagattg aaggtggccg ccaacacatt aagttggatc aattgaaagc
     3721 catcaaagat attctacagg tgtcttatga agatttgctt caatgactac ttgtagtcat
     3781 ttcgtttgaa attattatgt tacaccctta tgtgtcacga agaaatactg gtataataat
     3841 gaatgggata tgtaacgata gggtatactg ttatgttgcc taataaattg tggatcaaaa
     3901 tacaagaatg gagggatatc cttgtataag gcatatgaat tggattttac aaatgctgac
     3961 ttaaatgcat tctcctcaag ctcgcaatca tatacacatg tagtaaatca aatagatcac
     4021 aaccaaaaat ctattaacaa gagaatagaa aatctatttg aaagtgaaaa tgatttagtt
     4081 gattattatt ctaaggacag caaaattcta gatgcagacg aaattattaa agattggttt
     4141 ccaactataa aagcagatat ttttatatct cactctcatg ctgatgaaaa attagctata
     4201 cgttttgcat catggctatt tgaaaatttt ggtcttactg catttattga ttcttcggtt
     4261 tggggataca gttctgattt attaaaaaaa atagaccaaa aatattgcta taaggaacaa
     4321 acaaaaacat atgattatga taaaagaaat gtaacaacta gtcatgttca tatgatgctt
     4381 tctacagctt taaataatat gattgatagt acagaatgtc tgttttttct taatacacct
     4441 aattcaatta gtttgagcaa tgaaatcact aatgaacaga aatttacgta ttcgccatgg
     4501 ctatatagcg aactgacgac agcttcaata gtggaaaaaa agaatccacg attggaaagt
     4561 aatcctcaaa tgagcaccga ggatgttaga agcattataa agcactattc ttcgcaagaa
     4621 aatctgcaaa taaaatattc tttaaattta agtgaattaa cttatttacg aaaagctgat
     4681 ttgaaaaaat gggctttaga tgctgtggaa tgcactaaag gaagtaatac attagatatt
     4741 ttatataaaa acaccatttt cactaatctc taatcaattt actgaatcga aaggaaccgg
     4801 gtagaatgga taagaaagtt ttaataaaga ggttctctga agctattgaa aaaggaaatg
     4861 cagcaatatt tgcaggtgca ggattatcga tgtcacaagg atatgtaagt tggccggaac
     4921 tacttaatga tcctgcaaca gaaatcgggt tggattctaa aaaagaaaca gacttagtta
     4981 ctctggctca atattataaa aatgaaaatg gtggatcaag aggaattttg aatcagatac
     5041 ttatggataa ttttggtgaa gaattagaaa tatctgaaaa tcatcgaata ctagcaagtt
     5101 tacctattga aacttattgg acaactaatt atgatcatct aatagaaaaa tcaatccgag
     5161 aagcttataa aaaccctcag gttaagaaaa attatactca gttagcaaca actaatccaa
     5221 atgtggatac aattgtttat aaaatgcatg gtgatataga tgatgtcagt tcgacagtaa
     5281 taacaagaga tgattatgaa aaatatgatg attcgtacgc gttatttaaa gaaactttaa
     5341 aaggagattt gttaacaaaa acttttctct ttttaggatt tagttttaca gaccctaatt
     5401 tagaaagaat tttatcagat ataagatggg ttttgagaga aaaccaaaga cctcattatt
     5461 gtataatgag aaaaatatta tagaaaaaat tttaggttat cgctgaaagc cccggaaata
     5521 cgggcatttc gcaggatatg agaactcaat ttactaccaa tttactactt tcggattgag
     5581 ccgcatatat gctgaaccat actgctaata cccgccaccc caaatacggc acatcataaa
     5641 ttgaatacga caccgtaaac gcggcgttcc tctttcccgt catgggagaa caggacgccg
     5701 cttttttatg cccaaataga gaaaggaggc gacgccatgc tatttacttc cggccctgac
     5761 cgggcgtttg aacggctgat gcaggaaaag cccggtttcg atcactacga cggcggcggg
     5821 gcggacgcgc cggaggattg cggcacctgc cgattttacc gcccggattg gaaatatcaa
     5881 ttctgccagt ttgcagagtg tccctatcag ccgggcaagc tgaccgacta tgcagcggtc
     5941 aaattcacag tgaaaggagc gaacaacgct atggcagttt tccgtgtgga aaagaacaaa
     6001 ggctatacgg tgatgtcaaa tcaccacctg cggaataaga acctgacctt aaaggccaag
     6061 ggcctgctgt cgcagatgtt gtccttgccg gaggattggg actataccct aaaaggactg
     6121 tcctatatca accgggaaag catcgacgcg atcaggacag cggtatggga gcttgaaaaa
     6181 gctggatata tccggcgtga gcagggccgt gacgcaaaag gcaaaatggc cgatatggtc
     6241 tataccatct acgaacagcc ggtattggaa aacccggtat tggaaaatcc aacatcggat
     6301 aacccggtgt tggaaaatcc gacatcggat aatccggcgt cggaaaatcc aacgcaatta
     6361 aataaagaag tacaaagaac tgacttatca aaaaaagaaa aaataattac agatggacaa
     6421 agtacccatt ccattcctat cccatccccg acccctgccc ctatggaggg cgaggcagcg
     6481 gctacgccgc cggaacggaa aaggacagga aaggatgagg ctgtacggat ttatcgggaa
     6541 atcattttgg agaacatcga gtatgcctat ctcattcagg acaggagcat tgaccgtgaa
     6601 cagcttgacg aaatcgtaga cctgatgctg gaaaccgtct gcaccgcccg aaagacaatc
     6661 cgtgtcgccg gggacgacta ccctgccgag ctggtgaaat ccaagtacat gaagctgacc
     6721 ggcgaacata tccgctttgt ccttgactgt ctgcgggaga acacaacgaa agtccgcaat
     6781 atcaaacaat acctgcgggc tatgctgttc aacgccccca gcaccatttc caactactac
     6841 acggcccttg tcgcgcacga catggcacag cccgattggg gaaagcctaa atccggcctg
     6901 ccggactatt cctgcggcga gggcgaaagc ctgtaacgag aaaaggagga cgaccctatg
     6961 aagcagggcg cattgatttt tgacgagcga acagaccgtt acgacatccg ctttgatctg
     7021 gccgactatt acggcggcct gcattgcggg gagtgtttcg acgtgatgat cggcggcaaa
     7081 tggaggccca cccgcattga aatggccgaa aactggtatc ttgtcggcat ccgggccgac
     7141 gacctttccg gcctgcgggt gcggatttga cctatatcta cctgcggcgt ctggtggttc
     7201 cgccttagac gccgcttttg actttctgac aaggagggat gcgattgcag gaagaagtta
     7261 ctcaaaagac cattgccctg tccatgaaaa cgggcaagct cacggctcaa gtgctgcaag
     7321 cggcgctgaa aaagtacctg caacaccggg ccaagggcaa aaacacgctg caccacggcc
     7381 agcagagcct aaagcagctt aaaaagcatg gggctgatct ctccaacatt gagatcaccg
     7441 aggccaacat tggagcgttc aagccatgcg ccaagaaata cggcgtggat tttaccttac
     7501 gaaaagataa gaccacccag ccgccccact acgttgtgat tttcaaggcc aaggatgcag
     7561 ataaccttga tctggcgttt cgggagttta ccgccaagac gctttccaag gagcagcggc
     7621 cctctatccg caaggttttg tccgctgtga agcaaaaggc ggcggcccag accaagcagc
     7681 gggccaagga gaaaatcaag gaaagggggc tggaactgtg aagcctgacg taaagaaatt
     7741 gctgatcctg aacctcccgt atctgatttt tgtgtacctg tttgcgaaat gcggggaggc
     7801 gtaccggctg gccgctggtg ctgacctgtc ggggaagctc ctgcattttg cggatggttt
     7861 tgcggcggct tttgccaacc cgctgccaag cctgcacctg tttgacctgt gtatcggtat
     7921 cgccggtgcc gtgatcgtgc ggctggtggt gtactgcaag agcaagaacg tgaagaaata
     7981 ccgcaaaggc atggagtatg gcagcgcccg ctgggggacg gccaaagaca tagcgcctta
     8041 catcgacccc aagtttgaaa ataatatcct gctcacccaa acggaacggc ttaccatgac
     8101 cggcaggccc aaagacccca agacagcgcg gaataaaaac gtgctggtga tcggtggcag
     8161 cggttcaggg aaaacgagat ttttcgtgaa acccaacctg atgcaatgct ttccgaccac
     8221 ggactatccg acttcgtttg tggtgacaga tccgaaaggc actttggttc tggaaaccgg
     8281 caggatgttc cagcaggcgg gctaccgcat taaaatcctg aataccatta acttttccaa
     8341 gtccatgaag tacaacccct ttgtctacat ccattcggaa aaggacgtgc taaagctggt
     8401 aaataccctg atttccaaca ccaagggcga gggggaaaag tcagcggagg atttttgggt
     8461 gaagtcggaa cggttgtttt attcggccct gatcggctat atctggtacg aggccccagc
     8521 ggaggaaatg aacttctcaa cgctgctgga aatgataaac gccagtgaag cccgcgagga
     8581 cgacccggag tttcaaagcc ccgtcgatct catgtttgag cgtttggagc agaaagaccc
     8641 cgaccatttt gcggtgcgcc agtacaagaa attcctgctg tccgcaggca agacccgttc
     8701 ttccatcctg atttcatgcg gtgccagact tgcgcccttt gacatccggg aggtacgcga
     8761 gctgatggag gacgacgaaa tggagctgga caccatcggg gacgaaaaga cggtgctgta
     8821 tctcattatg agcgatacgg acacgacctt taatttcatt ctggctatgc tccaaagcca
     8881 gctaatcaac ctgctttgtg accgggctga tgatgtgtac ggcgggcggc tgcctgtcca
     8941 tgtacgcctg attttggatg aatttgccaa cattggccaa atacccaatt tcgataaact
     9001 cattgccacc attcgaagcc gtgaaatatc ggcctctatt attttgcaga gccagtcgca
     9061 gctaaaagcg atttacaagg acgccgccga gatcatttcg gataactgcg atagtgtgct
     9121 tttccttagt gggcgcggca aaaatgccaa ggagatttcc gatgcgctgg ggaaagaaac
     9181 gattgacagt ttcaacacca gcgagaaccg gggaagccaa acgtcccacg gattgaacta
     9241 tcaaaaatta ggaaaggagt tgatgtccca agacgaaatt gccgtgatgg acggcggcaa
     9301 gtgtatcttg cagctacggg gtgtgcgccc gtttttatcg gagaaattcg atattaccaa
     9361 gcatccccgg tacaaatacc ttgccgacgc cgacaagaag aatacctttg acgtggacag
     9421 atttttgact atcacgcgcc ggaaacggca gcaagtggta acgcaggatg aagtattcga
     9481 cctgtatgaa atcgacctgt cggacgagga cgccgccgct gaataaacag cggctttttt
     9541 cattccaaca acaaaatcaa aaaatcatta tgagccggaa accggcagaa agaggtaaat
     9601 ttatggcatt ttttaattcc gcagttacta ctttgcagac tatcgtgatc ggactgggcg
     9661 gcgctctgtg cgtatggggc ggcatcaatc tgttggaggg atacgggcag gacaatccgg
     9721 gggcaaaatc gcagggtgtc aagcagcttg tcgctggcgg cggcgtggcc ctgatcggtg
     9781 tcactctggt tcccctgctg tccgggctgc tgggctgatc ctggcctttg tccctgtcca
     9841 aacccttaac taatcgcctc cgcgtcctcc cggccagacc gggagggcgc gggaaaggag
     9901 gtgctacccg tgattagtga aatcattgaa gaatggataa aaggcatcct catggacggt
     9961 atcacgggca acctgtccgg gctgttcgat acggtaaatg ccaaagtcgg agaaatcgcc
    10021 gccgacgtgg gacgaacccc gcaggcatgg aacagcggta ttttcaatat gctgcacagc
    10081 ctgtcggaaa ccgtgatcgt ccccatagcc ggggccatac tcgcccttgt catgtgctat
    10141 gagcttatcc agatgataac ggaaaagaac aatatgcacg actttgacag ctccatgttc
    10201 ttccgctgga tattcaaatc cgcgtttgca atcctgatcg taacgaacac atggaacatc
    10261 gtcatgggcg tattcgacgc cacccaaagc gtcgtcaatc aaagcgccgg tgtgattatc
    10321 gggcagacat ccattgattt taacaccctg ataccagacc ttgaaagcca attggaggct
    10381 atgagcgtgg gcgctctttt ggggctgtgg ttccaaaccc ttgttgtggg cctcaccatg
    10441 aatatccttt ccatctgcat tttccttgtg acctatggcc gcatggtgga aatctatgtt
    10501 gtcacgtcgc tggggcctat cccccttgcc acaatgggca acgcggaatg gcgcggcatg
    10561 ggccaagggt atctgaaatc cctgctggcg ctgggcttcc aagccttttt aatcatggtt
    10621 gtggtgggta tctacgcggt gctgatacag aatatcggtt ccgcttccga catatccggc
    10681 gcaatctggg gctgtatggg ctatacggtg ctgctgtgct tctgcctgtt caagaccggc
    10741 agtatatcaa aggccgtatt cggggcgcat tgatcccaaa atccaagcat acacaggagg
    10801 aacttgttta tttcaacgta caacatcatt tacgctgacc cgccgtggcg gtatgactgc
    10861 aaaaacgtac agggcgcagc ggaaaatcac tattccacca tgagcattga cgagctgtgc
    10921 gccctgccgg tggaacggct ggcgtccaaa gactgcctgc tgtttttgtg ggccacattc
    10981 cccatgctgc cggaagctct gcggttaatc aaagcgtggg gcttttcatt caagaccgtg
    11041 gcttttgtat ggctgaaaca gaaccgtaaa agccttacat ggttttacgg gctgggccgc
    11101 tggacaaggg gaaacgcgga aatctgcctg ctggcaacac acggcaagcc gaagcgtcgt
    11161 tctgcctctg tccatcagtt tattatcagc ccgattgaac aacacagcaa aaagccggat
    11221 gtgacccgtg aaaaaatcgt agagctggcg ggcgatttgc cccgcgtgga gctgtttgcc
    11281 agacagaaaa cccccggctg ggacgtgtgg gggaacgagg tggaatgtga ccttatcctg
    11341 acgtgaaagg aggtgccaaa tggcttatgt aaccgtcccc aaggacttaa cccatgtgaa
    11401 aagcaaggtt gtgtttgggc ttaccaaacg gcaactgatc tgtttttccg gggcgctggt
    11461 gatcggcgtc cccttatatt ttctcacccg tgactatctt accaacagcg cggcggccct
    11521 gctcatggta tttgccatgc tgccgggctt tttgcttgcc atgtacgagc gtcacggcca
    11581 gccccttgaa gtggtgatta tgcagatcat ccagtgctgc ttcatccagc caaaggagcg
    11641 tccctatcag accgacaaca cctacaccgc ccttgtgcgg caataccaga tggaacagga
    11701 ggtaaaggcc attgtccaaa aaggaaatcc caagagaaac cgaaaaaaca aagctgaccc
    11761 gcgcccagcg aaaagaaatt gacgcggtaa tccgtaaata taagggcgac ggcaggcccc
    11821 acacggcgca gcagagcatc ccctacgagg tcatgtaccc ggacggcgtg tgccgggtat
    11881 cgcccggcgt cttttccaag tgcattgagt ttgcggacat cagctatcag cttgcccagc
    11941 cggacacgca gacggctatc tttgaaaaac tgtgcgacct gtataactat gtggacgcct
    12001 ccattcatat ccagttttct ttcctcaatc ggaaagttga cccggtgcag tacgccaaga
    12061 gctttgagat cgcgccgcag ggggacgact tcgacgacat ccgggccgag tacaccggca
    12121 ttctgcaaaa gcagcttgca aacggcaaca acggcatggt aaagaccaaa tacctgacat
    12181 tcaccatcga ggccgaaagc gtgaaagcgg cgcgagccag attgaagcgc atcggctttg
    12241 acctgttagg ctatttcaag agcatggggg ccgtagccca tgtgatggac ggctgggaac
    12301 ggctgaacct gctgcatggc gtgtaccacc cggacggcga gatattcaat tttgactgga
    12361 agtggctggc cccgtccggc ctctccacca aggattttat tgccccgtcc tccctgtgct
    12421 tcggcaatgc aaagacattc ggcatgggcg gcaaatacgg cgcggtaagt ttcctgcaaa
    12481 tcctgtcccc ggagctgtcg gacgatatgc tggccgactt cctcaatacg gaaagcggtg
    12541 ttttagtcaa tctccatgtg caggccattg aacagaccaa ggcgatcaag accatcaagc
    12601 gcaaaattac cgaccttgac gctatgaaga ttgcggagca gaaaaaggcc gtccgcagcg
    12661 gttacgatat ggacattctt cccagcgacc ttgccaccta cggcgaggac gccaagaagc
    12721 tgctgacaaa gttgcagacc cgcaatgaac ggctgttcca gttgacgttc cttgtcctca
    12781 acgtggccga caccaagcaa aagctgaata acgacgtgtt ccaagccgca ggcgtggccc
    12841 aaaagcataa ctgtcccctt gtccggctgg actaccagca ggaacagggc cttgcaagca
    12901 gcctgccgct gggcgtcaat cagatcaaga tacagcgcag ccttacgact tccagcgtgg
    12961 ccgtgttcgt cccctttgtg acgcaggagc tttttcaggg cggcgcggcc atgtattacg
    13021 gcatcaacgc caagtcccgc aacatgatta tgctggacag gaagcaggcc cgttgcccca
    13081 atgccttgaa gctcggcacc cccggcagcg gcaaatccat gagctgtaaa tccgagatcg
    13141 tcagtgtgtt cttaacgacg cctgacgata tttttatttc agacccggag gccgaatatt
    13201 acccccttgt caaacggctc cacggacagg taatccggct gtcgcctacc agcaaggact
    13261 ttgtgaaccc gctggacatc aacctgaatt attcggagga cgataacccg ctggccctga
    13321 aatccgactt tgtgctgtcg ttctgtgagc ttgtcatggg cggcaagaac gggctggaag
    13381 ccattgaaaa gaccgtgata gaccgggctg tgcgcgtgat ctaccggccc tatctggcag
    13441 acccccgccc ggagaatatg ccgatcctgt ccgacctcca caaagcgttg ttagatcagc
    13501 atgtcccgga ggctgaccgg gtggcgcagg cccttgacct gtatgtgtcc ggctccctga
    13561 acgtatttaa ccaccgtacc aacgtggaca tcggcaaccg gcttgtgtcc tttgacatta
    13621 aggagctggg caagcagctc aaaaagctgg ggatgctcat tgtccaagac cagatatggg
    13681 ggcgcgtcac ggccaaccga agccaaggaa aggccacatg gtattttgcc gacgagttcc
    13741 atttgctttt gaaagaggaa cagacggcgg cctattctgc ggagatttgg aagcggttta
    13801 ggaaatgggg cggcattcca acaggtgcca cccagaacgt caaagacctg ctttcctccc
    13861 cggaaattga aaatatcctt gaaaacagcg acttcattac gctgctcaat caggcgtccg
    13921 gggatagaaa aatccttgcg gaacgcttga atttgtccac cgaacagcag aagtacatcg
    13981 acaattccga acccggcgag ggccttttga tctttgaaaa cgtggtgctg ccctttacca
    14041 accccatccc gcacaacacc cagctttaca agattatgac gacccgctta aacgaggtgg
    14101 cgggagtatg acccggcgac gccacaaagg aggtgaacca ccatgaaaga gctgaaagcc
    14161 aaggcgaaag tgacgcaggc catgacccgc gacgggctga cgctggaaaa tcaggccacc
    14221 ggcgaggtgg agaacatttc cagccgggag gccgaacagg atttgtccgc gccggggccg
    14281 ggcggcaccg ccgataagct gctggaacgg gccgacgcca tccatgacgg ccataaggcc
    14341 aagaaagccg cgaagcaggc cggggctgtg gccgccgagg gggacgctgc cctgcaccgg
    14401 ccatccgccc ggctccaact gtcggaggaa gaacgggccg acccggattt acagccctat
    14461 atccgaaaat cggacaaacg ggccgataag ctggataagg cccgcgccgc catccccaag
    14521 aagcgcgtcc cggtcaagga aaccgtcttt gacgaggcaa gcggcaaagc aaagaccgtc
    14581 ctgcactttg acaaacagga caaggggcct ccctccctga aacccaatcc ggcaggccgt
    14641 cctgtttccg aggtttttct attcggccac gggaaaatcc atgaagtcga gcatgaaaac
    14701 gtgggtgtgg agggcggcca taagggggag gaacttgccg agcggcaggc cggaaaagcc
    14761 atccgcagca ccatccggca ccacaggctg aaaccctact gggacgcgga aaaggccgag
    14821 cgcaggctat tgtctgccaa cgcggagtat ttctaccaga aatctttgcg ggataacccg
    14881 gagatcgcac aggcggccag caaccccatt tcccggttct ggcagaaaca gcagatcaag
    14941 cgccagtacg ccaaggccgc ccggacagcg ggccagaccg caggcgcggc ggcacagggc
    15001 gcggccaaga cagccggggc ctccacgaaa gcggccaagg ccgcagccaa agaaagtgaa
    15061 cgggcggcct cctttgtggc ccgccactgg aaaggggcgc tggccgtcct tgtgttgggg
    15121 cttttgatgc tgcttatcat cggcggctta cagtcctgca ccgccatgtt cggcagcgcc
    15181 ggaagcggca tcacggcgtc ctcttacttt tccgaggata gcgatatgtt ggccgccgag
    15241 gacgcctacg cggagctgga agccgagctg caagactatc tggacaacta cgaggccacc
    15301 catgactatg acgaatacca ttttgacctt gacgagatca gccatgaccc ctatgtgctg
    15361 atttccattc tgtcggcgct ccatgacggg atatttacca tcggggaggt acagggtgat
    15421 ttgtccatgc tctttgacaa gcaatatatc ctgacagaaa acgtcgtggt agaaacccgt
    15481 taccgcaccg aaaccgatac atggacggac gcggagggca acacccatac agacacctac
    15541 caagtgccgt atgactatta catctgctac gtcacgctgg aaaacttcga cctgtcccat
    15601 gtgccagtct atatcatgga cgaggaaacg ctaagtttct attccctgta tatgtccacg
    15661 ctaggaaacc ggcctgatct gttttccggc agccagtacc ccaacgcctc caccctgacg
    15721 ccgccgacct actacgacgt acccccggag gctttggagg atgccacctt tgccgccatg
    15781 ctcaaagagg cggaaaaata tatcggttat ccctatgtgt ggggcggcag ctctcccagc
    15841 accagctttg attgcagcgg cttcatttcg tgggtaatca atcatagtgg atggaacgtg
    15901 ggacggctgg gggcgcaggg cctatataac atctgcaccc ctgtttccag ttcgcaggcc
    15961 aagcccggcg accttgtatt tttcaaggga acctacgaca cccccggcgt gtcccacgtc
    16021 ggcctgtatg tgggcaacaa tgtgatgctg cattgcggga acccgatttc ctacacgaac
    16081 cttacttcaa actactggca atcccatttt tacagttacg ggcgtttacc ttaacgccag
    16141 aaaggagctt tcaattatgg caaccaaact tgaccgcatc gaaaaggaca tccagaaaac
    16201 caagtctaag atcgcggagt ttcagaaaca gcttcgggag ctggaaacgc agaaaaccga
    16261 acaggagaat ttgcagatca tccagcttgt gcgcggcatg aacatgaagc cggaggaatt
    16321 tgccgcgttc ttacgcagcg gcgcaatgca ggccgcccct gccgcaaccc cttaccatga
    16381 acaggaggac aatgcccatg aagaataaga ccagacggat ttcccgtatt ctccccgcac
    16441 ttctggccgt gatgctctgc gtcacggcct ttcccgttac cgcccttgca ggcggcaatg
    16501 acccggcacc ggccccgctg ccggaggcta caaccgaacc cgctacgggc ggtttggagc
    16561 ctgaaacaga cgaaaccggc accgccacgg acgggacaga aaccgaggcc gaaaaagata
    16621 ccggccctct gaccggcaag gacatcaccg acctgttttc cgcgctgttc ggttccaagg
    16681 tgagcattgc cgccacggac gacggcatcc agatcaccac cggcaccgac aaaaaagaac
    16741 ctgaacagac cggcaccgtc accaccaacg gcggcaggct gaatgtccgc accggcgcgg
    16801 ggcttgacaa gaccgcgttc acccagcttc ccaatgggac gacggttgag gtagtcggca
    16861 cagacggcga ctggattaaa attctcttgc cggagcgcat cggctatgtc cattccgact
    16921 atatgaccgt cagcgaaaag gaagtagcgg ctaccggcga gggcggtttt tccctctcca
    16981 ttgacccgga ggaaattgct tctctgctgg aactgttcaa tggcggcggg gccagcgccg
    17041 ccctgtcccc ggacgggaac ctgtcactga ttgacgacat cggcagcgcc gcgaaaaatg
    17101 gcaagcagtt tatcaccgtg gaaaccaaaa acggcaatgt gttttatctg attattgacc
    17161 gggacgacga gggaaaagaa actgtccatt tcttaaatca ggtggatgaa gccgatctgc
    17221 tgacgctgat ggaggacggg gaaaccgtca cccccgctgc tgtctgctcc tgtaccacga
    17281 aatgcaaggc cggggctgtg aacacgaatt gcccggtatg taaaaccaac ctgaccgagt
    17341 gcagcggccc ggagccgcag gaaccccagc cggaggaacc cgaagccccg gaggaagaac
    17401 ccaagggcgg cgcgggcggc ctgatcgtgt tcctgctggt ggcgctggcg ggcggcggtg
    17461 cggcccttta ctatttcaag ttcaaaaagc ccaaggctga aaccaccggc agcgacgatt
    17521 tgggcgagta tgattttggg gaggacgagg atttggagga cgaggaaccc gaaaccgagt
    17581 ttgacccgga agctgatttt gtgagtgaac aggaggacga ggaatgacat ataaacttgt
    17641 aatcgcggaa aaacccagcg tggcccgcag cattgcgggc gtgatcgggg ccacggagaa
    17701 acacgacggc tatttggagg ggaacggcta tctggtgagc tggtgcatcg gacatctggt
    17761 gtcctttgcc gacgccggac gctatgacga gcgtttcaaa aaatggcgct atgaggattt
    17821 gcccattctc ccggaaacat ggcagtacat cgtccccgac gacaagaaac agcagtttga
    17881 cgttctctgt tcgctgatgc agcgccccga cgtgaccggc cttgtgtgcg ccaccgacgc
    17941 cgggcgcgag ggggaattga ttttccgttt cgtctaccag atggcgggat gccaaaagcc
    18001 ctttgagcgc ctttggattt cctctatgga ggacagtgct attaaggacg gctttgccca
    18061 cctgaaaccg ggcggcgact atgatccgct gtatcaatcg gccctgtgcc gggccaaggc
    18121 cgactggctg atcggcatta acgccacccg gcttttttcc gtcctgtacc acaagaacct
    18181 gactgtgggc cgcgtccaga cgccgacctt aaaaatgctg gtggacaggg acgccaagat
    18241 taccgatttc aagaaagaga aatatcacat cgtccatatc acggcgggcg gcgcggacgc
    18301 ggtaagcagc cgcttttccg acgctgccga ggcaaacacc gtcaaggcgg cttgtgcaaa
    18361 agcgcaggcc gtttgcgttt ccgtgacgcg ggagaaaaag acggaacagc cgcccaagct
    18421 ctatgacctt accaccttgc agcgggaggc taaccggctt ttcggctata ccgccaagca
    18481 gacccttgac tatgcccagg cactgtatct aaagaagctg ctgacctatc cgagaacgga
    18541 tagtcaatat cttaccgacg atatgctgcc cgccgtggaa agccttgtgt ccggcctgtg
    18601 ggagctggtg ccgtttgcca agggcctgaa cctttccccg cagtttgacc gcatcctgaa
    18661 cagcaaaaag gtgtccgacc accacgccat tatccccacc gctgaatttg tgaagcaggg
    18721 ctttggcact ctggccgaga gtgaaaaaaa gctgctgtcc ctgatctgct gcaagctctt
    18781 atgtgccgtg gccgggccgc atatctatga ggccgtcacc gccacattta cctgtgccgg
    18841 gcaggagttt accgccaagg gcaagaccgt cctttccccc ggctggaaag agattgaacg
    18901 ccggttccgt tcttccttaa agaccgacgc cgacgaggac gccgaggcgg tgcgggagct
    18961 gccggagctt tgcgagggcc agacctttgc agacgtggcc gcctctgtca ccgagcattt
    19021 caccacgccg cccaagccct acaccgaaga tacgcttttg tccgctatgg aacgggccgg
    19081 ggccgaggat atgccggagg atgccgagcg caagggatta ggcacaccgg ccacccgcgc
    19141 cgccattctg gaaaagctgg tgcagatggg ctttgtccag agaaaaggca agcagctcat
    19201 tcccaccaag gacggcatca atctggctgt ggtgctgccg gaggcgctta cttctcccca
    19261 gcttactgcc gaatgggaaa accggctgac cgagatcgcc aaggggcagg ccgatcctga
    19321 cgaatttatg gacggcatcg agacgcaggc gcgggagctg gtgcagacct attcctgtat
    19381 cagtgaggaa aagcagaaat tgtttcaggc cgagcgtgtt cctatcggga cgtgtccccg
    19441 ctgtggtgag gctgtctatg agggcaagaa aaactactac tgcggaaacc gggcctgcca
    19501 gttcgtcatg tggaagaatg accgattttt tgaggaacgc aagaaagcgt tcaccccgaa
    19561 gatcgccgct gcgctgctca aaaccggcaa agtcaaggta aagggcctct attccgtaaa
    19621 gaccggcaaa acctacgacg ggacggtgct tttggctgat accgggggca agtacgtcaa
    19681 ctaccgcatt gaacacagga gctaaaggac agtaacacag caagcatagg gagtgtggct
    19741 acactcccgg taaaatcccc cggccgcgtc cctgccgggc cggggatttt tgcttgttgg
    19801 ggaagtcccc aaccccctat tttttgaaac agaacagaga aaggagtgac cgcgtgaacg
    19861 aagtattttc tatccaagtc cataaccggc agtttttgga acagggcaaa caaggcgtct
    19921 ggctggattt gcccaccaca accgaaacgc tgcaagccgc cctgcgggat gttggcatta
    19981 ctgccgacaa tccgcaggat ttttttatca acgggtattc ctgcccggag gacagacacc
    20041 ttgccattcc ctatgacatg gtgctggccg ccgacgtgga cgagctgaat ttccttgccg
    20101 cccggctggg ccagcttgac gccgccgaga tcgcagagct gaacgccgcc ctgcaaaatc
    20161 cccgtggcgg ctttgagaat atcggccaga tcatcgacta caccgaaaat gtggattact
    20221 atgtgcatct tcccgacgtt aggggggatg gacagttggg cgactactac ctgaaccgtt
    20281 ccggcatggt ggatatgccg gaggaatgga aagccgggat tgatacggcg cagtttggac
    20341 gccacattgc ccagcaggaa caaggcgttt ttacccagta cggctatctg gtgagaagcg
    20401 gcgacgaatg gcagcgcgtc catgagggcc agccggtgcc ggaggaatac cgggtgatgc
    20461 actaccccca gccggaagct gaccgggagg aaccgcaggc ccagcagccg gaggcatccg
    20521 aaagccccga caaagcgccg cccccggtta tcccgatcat gctggacggc atgaacagca
    20581 aagaacgcat gaaagtgatt actgaccgtc tggaaaccgg cgtacaggag ctttttgaaa
    20641 gtagccgcta tatggcttac ttatccgcta tgtccaagat gcacgattac agtctgaaca
    20701 atacgctgct gatcgccatg cagggcggtt cgattgtggc gggctataac aggtggcagg
    20761 atgaatttga ccgccatgtg aagcggggcg agaaaggcat taagatactg gccccggccc
    20821 cgttcaaggt taagcagcag atggagaaaa ccgacccggc cacccagcag cccgtgatcg
    20881 gcgcggacgg caagcccgtg accgaagaac aggaagtgac ggttccggcc tttaaggtgg
    20941 tgacagtctt tgacatcagc cagaccgagg gcaaggattt tcccatgccc tatatcagtg
    21001 aacttaccgg cgacgtgcag cagtatcagg atttctttgc cgcgctggaa cggacatcac
    21061 cctatcccat aagcattgag ccgatttcag acggggccaa gggccgctgc ttctacgcaa
    21121 aacagcgcat tgccatcaac gagggcatga gcgaattgca gaccctaaag accgccatcc
    21181 atgagattgc ccatgccaag ctccacgcca ttgaccggga ggcccccgcc gaggaacagg
    21241 cggcccggcc agaccgcagc acccgcgagg tacaggccga aagcgtggcc tataccgtct
    21301 gccagtatta cgggctggac acgtcggact attcttttgg ctatgtggcc gattggagca
    21361 gcggcaggga gttatccgag ctgaaagcct cccttgaaac catccgggcc acggccagcg
    21421 aattgataac cgagatcgac ggccattttg cccagcttca gcaggagcgc gaggcccggc
    21481 aggaacagga ggccgtcacg gttgacgtta ccccggaggc agcggccccg gcgcaggccg
    21541 aggaagaaca ggccccggcc cttgatccgg cagccgagcc gcttgtgact gtgctatgga
    21601 gcgaaagccc ccagctaaag gacggccagc aaatgccgtt gcatgaggcc gacgcgctgt
    21661 ttgcccgtct ggatgcagca tatccggcag aggcaggcta tgacaaaacc gcgttccgca
    21721 ttgactgtat ctttcagggc gagccggaca gctacgaggg gcggcaggat tttggagata
    21781 gggacggttc cctgatcgaa catatccaga gctaccacca attttacgcg caggacgaaa
    21841 actggaaaaa gcatgtaatc gctacaaccg gcatagaggg ctgggagcag gacaaggccc
    21901 atcgggatat gctgttaggc gagtttgtcc cctatatgaa gctgcattgc agccttgccc
    21961 aaatggaaca gacggcgcag ggccgcttac agtccgggga aaccctgacg ccggaggaaa
    22021 cggcctattt gggggcgctt ctctcttatg tgcaggagtg ccgccccatg ctcaatcagg
    22081 gccagtatca gttgccggag ccgccgaaac tggctgactt cgaccagagc ttgcaggact
    22141 acaaagcaca ggtacaggcc gagatcgcgc aggaggccgc cgcagccggt atgaccgtgg
    22201 aggaatacgc ggcggctggc tatgaagcac cccaacagga caccttttcc atctaccagc
    22261 ttcgaggcgg ggaggaaacc cgcgactatc ggtttgagcc atacgagcgt ttacaggccg
    22321 cagggctggc cgtggacagt gccaactatg accttgttta tacggcaccg ctggataaaa
    22381 gcacgtcttt ggaggatatt taccgcacat tcaacatcga ccacccggca gattttaggg
    22441 gacacagcct ttccgtttcc gacgtggtgg tgctgcacca gaatggacag gacaccgccc
    22501 actatgtaga cagcttcggc tatatggaag tgccggagtt tttgcgggaa aatcccctgc
    22561 gtaccgccga actgtctacg gagcagaacg aaaacatgat tgacggcatt atcaacaata
    22621 cgccgcccga accgcagccg gaggaacccg aacagctatc ttttgaggat gtggcagttg
    22681 cttccggcca gacacaggag gaacccccgg aggctgcgcc cccgcaaacg gctgtccgct
    22741 attatcccat caatgaggga gccgcccgcc gcgccaagga agccatgagc ttttctgact
    22801 accggcccgg cagcgccacg gcggaatacc ggcactatgt cgatcaggcc gtggaaattg
    22861 cggagcgcca gaaaaagcgt gtggagccag agtatcacga aaagatagac agcctccttg
    22921 acacctacgc ccgcaagctg gccgagaaca tgaataaggg ctatgagatt accgcccgcg
    22981 tcccctctgt cctgattgcc gggccgtcca atttcccggt acgggcgaaa gaaaagcaga
    23041 acgccgccag tgaccgcaac atggaggaat ttcagtacat tcagggcttg cttgacaaaa
    23101 tccgcagcac cggcatgggt ggtatcagcg ccgacgatcc gcaggccgtt tccaagctgg
    23161 aaaagaaact ggaaaagctg gaagcgtcgc aggagttgat gaaggccgtc aatgcctact
    23221 accgcaagca tgggacgctg gacggatgcc cccatctgat cgaaagaggc attgaaaacc
    23281 tgaaagcgga tatggcgtcg ggctggcact atgagaaaaa accgttccag tcctggcagc
    23341 tctccaacaa taacgccgag atacgccggt taaagggccg cattgaggaa ttgacccgcc
    23401 aaaaggaggc ggcctatgtg ggatgggagt ttgacggcgg cactgtggag atcaaccggg
    23461 tggccaaccg cctgcaaatc ttctttgagg ggaagccgga tgctgctgta cgcgacgagc
    23521 tgaaaagcaa cggtttccgc tggtcgccca aggccggggc atggcagcgg cagttaaacg
    23581 acaccacaat ccgcgtcgct gaccgtatca agtgcatcca gcccctttcc ggcgaaaagc
    23641 ccagcgcctt acagcttgcg gcccgcaggg agaaagaaaa gccctctatc cgggcgcagc
    23701 tcaacgcggc caagaccgaa caggccaagc agccaccggc gcgggaaaaa tcaaagggat
    23761 tggaggtaga gtaaatgcag aagtttgaaa atgtggacgt tctggccgcg ctggaacaga
    23821 tcatgcggca gaacaccgcg ttttatcaaa gtgactttgg cattgacaaa gacattatca
    23881 ggcgggatgc cgccagcgat caggccgcag acaagaccct gctctggatg tcccggccct
    23941 ccgggacgta ctgtttccgg gaacgtgatg ttttcctgaa agacacccga cagtacaaca
    24001 catggaaatt ttacggggag cagacccgtg acaagatact ggcctacgcg gtggagctga
    24061 ccggcacaca gggcggcact atccggggca atctctatga gctggactat ccgcagcatt
    24121 tccggcacgt cattgaaacc gcccagccgg tgagtgtgaa ccggctcttt tatgagcatg
    24181 gcacccgtga catcccggag agccagcgtt ttgacggaag ccctgaccgg gtattgggaa
    24241 actttttgta ctatgaggcc cagccccatg acccggctgt gctgcaggag gcgctacgga
    24301 cggagcagca cagccggggg cgggccgtcc ccggcgattt caaagtccac gtcaccgctt
    24361 tgcatgacag ccggattgaa accgaggccc ggcgtattgt ggacagcctg aaagatctgt
    24421 ccgcgcctaa cagccccaat aaaacgcatt tcatggtgga gatctccccg cactttgcgg
    24481 cgattgcttc caccaaggat aatgaccggc tctttgccat gctgccctat aaatccctgt
    24541 gttttaccgg gatgaaaggc aggcatggcg tgtatgccgt gattaaccgg gacgagcgcc
    24601 gggatgtgag tattcgcagg ccccggccct ctatccgcaa gcagctatcc gacagcaaac
    24661 aggccgccag cccaaaaaag gcggcggcca gaaccaaaaa gaatgaattg gaggtataag
    24721 gaatgatgca ctttaccgtg gaggaagaaa acctgatctg tatgtaccac aatgcagacc
    24781 ggcgcagaac gataaacagg ctcaccgccg tcatgccggt tatggatggg gatatgcggg
    24841 cgcaggccca gcagaccctt tccaagctgg aacgcatgac ggatgccgac tatgacggcc
    24901 agaagttcca cttcacagac gaataacgaa cagcagacgc cgggcgcggc ggccatgtgg
    24961 tcgcttgcgt ccggcgtctt ttctttttgc ctattcctac gcatttagaa cccggtattg
    25021 tcggggatag gatgaagtat tcgcttgccc ctgcaaacat gcgggagaag ccttgcagcg
    25081 ggcggttttc aatcccttaa atgcgtaggt tgcagctata attagacccc tgaaacagat
    25141 atagccgcgc agcgggtgta tctgtttcag gggtgtgcag gtgatagccg caaagcggcg
    25201 taagagggtg cagccctctt gccgtctatc tctgttccag cgggaagctc ggcaatgctt
    25261 ccagcagttt cagggaaatg cgctgccgta tatcttcgtc aatgactttc ttctttttgc
    25321 cgtttgcctg tctgatctcc accgtggaaa gctcgttgat gtagtcagca taatgggcca
    25381 acactttttc cgtggcccac ctctcaccgg caacggcggc tttgatcgtt tcatagtcca
    25441 gcagcttttc ttgtccgtcc atcctgatac ccccgtcaga ctgatttttt ctatgatacc
    25501 atattcggaa gcatggaacc agagaaaacg gcgcttttct gctggtaaat tctacgcatt
    25561 tagaacagca cttcggcggg gataggataa aacacccaca taccccgctg accatgccgg
    25621 aaaagccttg aaatataagg gcttttacag ctctaagtgc gtaggtttcc agtatctttt
    25681 ccgctggcgc tcggcctctt tgcggcggcg catccgtttg gagcaggccg cgcagtattt
    25741 ggcccggtta gacttcggcg tgaacgtggc cccgcactca cagcagcgtt tcacttcgtc
    25801 ccggtctttg gtgatctcgg catacagggc cgcatccagc gggaggacag cggccttaaa
    25861 ccagcggcac agaagcgaat aggaaatgct ctgtacgcaa atacattctt cgccgtcgtc
    25921 cagcaacagg cagttgccgt cacaatagtt gcagcactca tgcgtcagct tccgggcctt
    25981 gcgatattga gggtaattca ttcgtggaat actcatagct cttgcgtcca ttcctttccc
    26041 ggcgtcatac gcaaaatgcc gtccacattc tgcttgatga tgccgtattc ctgcatctgc
    26101 tttttcgctt cgccgtactt ctcatacagc cgttcctttt cctcggccaa tcgcttgtac
    26161 tcggctttca gggcgtacag atcggggagc tttttcacac cctgtccctt tagggccttt
    26221 gccgcagctt catacaaaat caacgtgctt tcatgctcac gccggaattt tgccttatcc
    26281 gctgcattgc ggtattccat agccacgggc cagagctgct tgtaggtaga aatattcttt
    26341 atcagcaccg ccatatccgc aagccggtgt tccatagctt tgagggtagc ggcggcctcg
    26401 tcgctggcgg cggtgatctc ggccactttg ctttccaaat ccgggtaggt gtctatccca
    26461 tgttcagtca ggaaattcaa agtctttgcg gcctgcttca aattgtggag cttcgcccac
    26521 ctctcatagc ctgccgactg ctgggcctta atgttgtttt ccagatcaat ccgcaaagaa
    26581 atccccttgc gctctttggg cgctctggtg ataacgcggc ctttgatacg ctctttgatg
    26641 gcttcctcgg tgtaggcttc ccccaatgtc ttgcagcggg taaagcgttc ctgtccggga
    26701 gcgcggaaag aaataaactt tcccggcttg atctcatagc cctgcgcctg catgagccgc
    26761 aggaaatcat caaaatcttt tgcctgcggg atagcggcgt caatggctgc tttgagcttc
    26821 gctttccagc tcgtcccttt ccgctgggcg tcccactcgg catagctctt gcccttactc
    26881 tggccgggct tcaccacgga caatccgttt tccttgcaca gcctgtcgct ggtgcgccgg
    26941 atataggcat agctctgttt gttggaaatg tacttgcgct gatttaccat atccacggca
    27001 cagaaaataa tgtgattgtg gacgtggccc ttatcaatat gggtagtcag cacataggga
    27061 tatttccctt gcagcacttc ctcggcaagc tgcttcccga tctcatgggc ctgttccggc
    27121 gtggcttcgc cgggggcaaa ggattgtatc aggtggtggc ccagattatt gcccttttgg
    27181 tatgcctgcg ccagcagcat ttcaaattca atgtccgctg tttcataaga gcaggcaaag
    27241 gaggccacca gcagcttgcc gtcagttttg tccgggttct cgatgtagtc aagggctttt
    27301 ttcagcgttg acttgatagg atgtatcttt gtaactgcca tatctgcgcc agcgccccct
    27361 ttatatcctc gatgtcctgt gcgtacaccg gccccatacc gttcagcctc tttgcaatct
    27421 gattgacgtt gacgccgatc ttctgtatct cggcggtctg cgcccggatg tcgctggtgt
    27481 ccatgttgac gatatagccg tcaatgagca tcttccgggc gtaggctgaa aagttcttcg
    27541 tatgcagcag cgccattttc tgttcaatca tagcccgttc ctccggcgtc acagggacgc
    27601 gcagcacgat ttttcgcttt ctgtttgcca tgcttcaccg tcctttccat tcaggggttt
    27661 ggggatttcc ccaacaagca aaacggacgc ggcccggcag ggacggggca ggccgttttt
    27721 ccgggagtgg ctacactccc tatgcttgct acgttactgt ttctccacta acaagacgtt
    27781 tccaaagccc caaactaccc gcaaaatagc cctctggaaa gaaaaaagtg caaaaaaata
    27841 gaagctacgc tgtgcagctc ccgctaaaag taaaacagag gatgccagtt acacatcctc
    27901 cgtttcattc ttcttcggct tttcaattag tatggcgctg tcaatcgcgc cctcgatgat
    27961 cggcaggtat tcttcggggc agagtttcag cttgtggctg accctttgcc gcagttcgct
    28021 ttcctcccgc atgatctccg ggttaaagta gcgttccaca ggaagcccgc aggctttaat
    28081 aagctgtatg acaaccggca gactgggaat ggcccgtcgt tttcgatgtt ggcaagatag
    28141 cgccagtcaa tatttatttt ctctgccatt gctttgcgcg aaacgcgctt tgcttgccgg
    28201 gccgctttca catccgcgcc gaaagtttca aagccgggac aatcttcaat attcgccata
    28261 tcgcacctcc cacttacatt gtatatttca tactctgccc gtggaatgtt ggtatatgca
    28321 cctttcttaa agtttatatt tcacattttg tttcttttat tcttcgagca aaagaattat
    28381 aatgtaccct gtggaggtgt actatggact acatgacgtt gaaagaggca ggcgagaaat
    28441 ggggtgtgcc cccacgatgg ataaactact attgtgctgc gggacgcatc cccggcgctg
    28501 taaagatggc gacgatctgg ctcattccca aaactgcgga aaagccgatt gacaggcgta
    28561 caaagaaagg aaaggcggtt actgaatagt ataatgaaac cggcgcattt tggatatggt
    28621 tttgaagaga gagaaagcat ggtattttgt cacggaaaaa ctataagatg atagatggca
    28681 ggctgctcca gaccgataaa aagtattctc atctgaaaca gaaagaaaag atttacacat
    28741 ggatgtatga agaagcgaaa ctttatcatg acagaaatgg aaaatgcccg aaacaaagac
    28801 gaggaagctg ctgctgtatc agccgtatat ggtagaattg aaaaggccgg catctggatt
    28861 ctttatggtg aagtctccag acattggata actgctggtc taatgcgcct ttgagtatgg
    28921 ggtgattgat tttaataccg gggaggtacg gctttttgag gaaaatattc tgggatttac
    28981 atttggcgat tattacattt cctgtaactg caaggacacg gatgatgaag atatgaggaa
    29041 tatagacttg ctgattttct actgtcttga acggtattag gactgaatct gctgcgcgga
    29101 gtgcggcaag agcgaccgga gggagtacac acaggccctg cctgtgtgaa aagccatacc
    29161 gcaaggtgca ttcgcaaaaa agaggccgcg cattttgctg aggcttgggg tgtccccaac
    29221 aagcaaaacg agaacgccgc aggcgggcaa gtggtggatc agaatatccg taaaggatat
    29281 tctgatccat tgcttgccag tattatcggg atgttttgac aaccgctgta atcgaaacat
    29341 cccaaacatt aagaaggtgt taattattat tatcttgatt taattcgttt aaaccaataa
    29401 tatagataca tacaccatga aaagaagcga gtatcccaat gacggatgat taaaatccga
    29461 aaagaaatcg ctttgaaact acagggaaac tacagactgt tatgttatct tcttaaaatg
    29521 gagggatttt tatgtcgata cgaattctac ttgtcgagga tgatgatcat atctgtaata
    29581 cagtaagggc gtttctggct gaggcaggat atcaggtgga tgcctgcaca gatggaaatg
    29641 aggcatacac caagttttac gaaaacactt atcaactggt tattcttgat attatgctgc
    29701 ccggtatgaa cgggcatgaa cttttgcgtg aatttcgtgc gaaaaatgat actcccattc
    29761 tgatgatgac agccctgttg gatgacgaaa accaaatccg ggcgtttgat gcagaggcag
    29821 acgactatgt aacaaagcca ttcaagatgc agattttact aaagcgggtg gaagccctgc
    29881 tgcggcgcag cggtgcgctg gcaaaggaaa tccgtgtcgg caggctgaca cttctgccgg
    29941 aggatttcac ggtactttgt gacggtacag agctgcccct gacacgaaaa gaatttgaaa
    30001 tccttttgct gctggtgcag aacaaaggca gaaccttaac gcatgaaatc attttgtcac
    30061 gtatatgggg atatgacttt gagggtgatg gcagcacagt ccacactcat atcaaaaatt
    30121 tgcgggccaa gctgccggaa aatatcatca aaaccattcg cggtgtagga taccgattgg
    30181 aggaatcata ataatggaaa gaaaagggat tttcattaag gttttttcct atacgatcat
    30241 tgtcctgcta ctgcttgtcg gtgtaacagc aacactgttt gcacagcaat ttgtgtctta
    30301 tttcagagtg atggaattac agcaaacagt aaaatcctat cagccattgg tggaactgat
    30361 tcagaatagc gataggcttg atattcaaga ggtggcaggg ctgtttcact acaataacca
    30421 atcctttgag ttttatattg aagataaaga gggaagcgta ctctatgcca caccaaatgc
    30481 caatacatca aatagtttta gacccaactt tctttatgtg gtacatagag atgataatat
    30541 ttcgattgtt gctcaaagca aggcaggtgt gggattgctt tatcaagggc tgacaattcg
    30601 gggaattgtt atgattgcga taatggttgt attcagcctt ttatgcgcgt atatctttgc
    30661 gcggcaaatg acaacgccga tcaaagcctt agcggacagt gcgaataaaa tggcaaacct
    30721 gaaagatgta ccgccgccgc tggagcgaaa ggatgagctt ggcgcactgg ctcatgatat
    30781 gcattccatg tatgtcaggc tgaaagaaac catcgcaagg ctggaggatg aaatcgcaag
    30841 ggaacatgag ttggaggaaa cacagcgata tttctttgcg gcagcttctc atgagctaaa
    30901 aacgcccatc gcggctacaa gcgttctgtt ggagggaatg cttgaaaata tcggtgacta
    30961 caaagatcat tctaagtatc tgcgcgaatg catcaaaatg atggataggc agggcaaaat
    31021 catttccgaa atactggagc ttgtcagcct gaatgatggg agaatcgtac ccatagctga
    31081 accgttggac atagggcgca cggttgccga gttgctgccc gattttcaaa ccttggcaga
    31141 ggcaaacaac cagcggttcg tcacagatat tccagccggg caaattgtcc tgtccgatcc
    31201 gaggctgctc caaaaggcac tatccaatgt catattgaat gcagttcaga acacgccgca
    31261 gggaggcgag gtacggatat ggagtgagcc tggtgctgaa aaatgccgcc tttttgtttt
    31321 gaacatgggc gttcacattg atgatactgc gcttccaagg ctgttcaccc cattctatcg
    31381 cattgatcag gcgcgaagca gaaaaagtgg gcgaagcggt ttaggacttg ccatcgtaca
    31441 aaaaacgctg gatgccatga gcctccagta tgcgctggaa aacacctcgg atggcgtttt
    31501 gttctggctg gatttaccgc tcacatcaac attgtaaata tttaaaactt aaatgatttt
//
LOCUS       DBBGSP010000032        30825 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000032 DBBGSP010000000
VERSION     DBBGSP010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30825
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.032"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..106
                     /locus_tag="ACIZE9_001740"
     CDS             <1..106
                     /locus_tag="ACIZE9_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6093602.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            428..1207
                     /locus_tag="ACIZE9_001741"
     CDS             428..1207
                     /locus_tag="ACIZE9_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093603.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSYVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            1253..2197
                     /locus_tag="ACIZE9_001742"
     CDS             1253..2197
                     /locus_tag="ACIZE9_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGC6093604.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVAIVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            2213..2992
                     /locus_tag="ACIZE9_001743"
     CDS             2213..2992
                     /locus_tag="ACIZE9_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HGC6093605.1"
                     /translation="MEETINLEEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            3004..3702
                     /locus_tag="ACIZE9_001744"
     CDS             3004..3702
                     /locus_tag="ACIZE9_001744"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HGC6093606.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3730..4494
                     /locus_tag="ACIZE9_001745"
     CDS             3730..4494
                     /locus_tag="ACIZE9_001745"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HGC6093607.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQITAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            4539..5228
                     /locus_tag="ACIZE9_001746"
     CDS             4539..5228
                     /locus_tag="ACIZE9_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGC6093608.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            6455..7135
                     /locus_tag="ACIZE9_001747"
     CDS             6455..7135
                     /locus_tag="ACIZE9_001747"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGC6093609.1"
                     /translation="MIGIEEKKGVQKDVTIDREENLRGHRFYWIGRRAQDIFFSALAL
                     IALSPVMLITALAIVIDDPGGSPIFVQDRVGRNGKLFKFYKFRSMCVDAEAKLEALLA
                     QNEMDGPVFKIKDDPRITRVGKFIRKTSIDELPQLWNILKGDMSIIGPRPALPREVEQ
                     YGDYERQRLFVQPGLSCYWQIAPHRNELSFEEWVELDVKYINERSFITDWKIIFLTLQ
                     AVLFGYGE"
     gene            7164..8477
                     /locus_tag="ACIZE9_001748"
     CDS             7164..8477
                     /locus_tag="ACIZE9_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGC6093610.1"
                     /translation="MNIILLSGGSGRRLWPLSNDIRSKQFIKLFKDENGEYESMIQRV
                     YRQITTVDPDAKVTIATSKSQASAIHNQLGDKASICVEPCRRDTFPAILLAAAYLHDE
                     LGVGDDESVAVCPVDPYVDNSYYEGVEALEKLVQQNTANLTLMGIAPTYPSEKYGYII
                     PESSNEVSTVKEFKEKPDKATAEKYLAQNAVWNAGVFAFKLGYLLEKAHAMVDFEDYR
                     DLYSKYETLTKISFDYAVVEKETSIQVMRYNGDWKDVGTWNMMAEVMADNIKGKAVMD
                     DTCVNTQIVNELNIPILAMGCKDMVIAASGDGILISDKERSGYMKPYVEKISTEVMFA
                     EKSWGTYTVMDVQEGSMTVKVSMQAGQKLSYHYHNSRDEVWTVVAGQGKAIVDGMKQI
                     LRAGDVVTIAAGCKHTIEAVTNLDIIEVQIGETISVADKYKSSLN"
     gene            9307..10050
                     /locus_tag="ACIZE9_001749"
     CDS             9307..10050
                     /locus_tag="ACIZE9_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HGC6093611.1"
                     /translation="MSRMRFMNTEIDNLTMGEVLVEVEKMIQDRRCGYVVTPNVDHIV
                     QLETGKELQDVYKNASLILTDGKPLIWISKFYKTPIKEKISGSDIFSLLCKMAAEKGY
                     TMYFLGAAEGVAAKAADNLMKRFPGLNVVGTYSPPYGFEKDEDEMFKIDSQIKRANPD
                     MLIVGLGCPKQEKFMFYNCDRLGVPVSFGLGASLDFEAGNVKRAPKWMSDYGFEWLFR
                     ITQDPKRMAKRYLVDDLKIFKLALKYRKK"
     gene            10077..11078
                     /locus_tag="ACIZE9_001750"
     CDS             10077..11078
                     /locus_tag="ACIZE9_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HGC6093612.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFRENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSTELSYSRTERVTNIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALKGKYADKKKLVDKAIYLERVLCNEAGGWQDQIAAAYGGFNRI
                     NFNSDGYEVLPIIITPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAVLTDKNRDLDDFGRLLDLTWRLKKATGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQNAVRSAMSNLMYIPFEFENGGTQVIHYTPEMYIPK"
     gene            11101..12387
                     /locus_tag="ACIZE9_001751"
     CDS             11101..12387
                     /locus_tag="ACIZE9_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HGC6093613.1"
                     /translation="MKVVIMAGGKGTRISSVASDIPKPMIKIENKPVLEHEIECLRDQ
                     GFTDIILTVSHLGDIIMNYFGDGSGISPVTGQPFDVKIEYFLEKEPLGNAGALFRLKD
                     NLTEDFLLLNADAMFDVDFNRFVAYHREKGGLVTLFTHPNSHPYDSGLIIADKDGSVD
                     RWLVKEDSRPTYYRNRVNAGLHVISPAVLDVEINTPKIDLDRQLLKPLAGTGKMFCYD
                     SPEYVKDMGTPDRYYAVCEDFKAGRVKGKNLQNKQKAVFLDRDGTINQYVGFLRHIDE
                     FELIKGTEDAVKKINAAGYLAIVITNQPVIARGEVSFEELEEIHNKMETLLGYKGAYL
                     DAVYYCPHHPHKGYEEERPELKFDCECRKPKPGMLIQAATDFNIDLSQSWMIGDGEND
                     IKAGQAAGCKTALVGESEYGQDMTIATLSEFADKIC"
     gene            12421..13074
                     /locus_tag="ACIZE9_001752"
     CDS             12421..13074
                     /locus_tag="ACIZE9_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGC6093614.1"
                     /translation="MIDNRLQKHIDLLIKRYPTLEVIKQDIVDGYLIMEECYLNDGKL
                     LIAGNGGSAADSEHIAGELMKSFKTPRPVSREFADKLIAVDPVKGSELAKNLEYGLMA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRPGDVFLGISTSGNSKNVINATVVARA
                     LGMKVIGLTGAKGGELARVADVCVKAPETETYMIQEYHLPIYHCWCLMLEDKFFGNR"
     gene            13107..14312
                     /locus_tag="ACIZE9_001753"
     CDS             13107..14312
                     /locus_tag="ACIZE9_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC6093615.1"
                     /translation="MNVLFITTQFPYPLDNGGKIGAYNGISVLSRDYDVTVLSFTEEP
                     QYVEEGVSFFREKFNSVKFENPVIHDVHIRNNPMKLVEALAIGYCLRQPYIVSKFYDS
                     KMLQLIDEKFSNNAYWDIIFIDYLNMQSYGQYIREKYKTQFGKYILKDHNIEYDLVLQ
                     EAESSRGLKKKLLQLEYKRTRKYEEAAVNRADYCFSVCDANTEVLKKINDNSYTMLPT
                     YEMLTGVKKNIEKNTILYLGNLSWKSNMQGLVWFLESIYPNIQQRIPDVKITIVGSGP
                     VGTDFSKYSGVDYRGYVKDISHIYDDQAVLIVPLLEGSGIRIKILEAFNNEIAVVSTL
                     VGCDTIGAKDGSELFIADNEKDFATAVVRLLEDMNLNEKVRKNAKLFLKEKYSLTARQ
                     DEFSAIINS"
     gene            14388..15767
                     /locus_tag="ACIZE9_001754"
     CDS             14388..15767
                     /locus_tag="ACIZE9_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093616.1"
                     /translation="MEIRISYYFRKLLLFYVCVIVAAMSYHLTGNSNVASLIAVVGVV
                     YAIVKACNNEYLAIWVMFVLGSDIWGIVPYINIGSGVLHWSDFNVIVAIFLCLRFIKV
                     KARSRYGIVYSVMLIFILIACVQSHSIYGQDVHTTLLTARELLVVISFWPIVKIVYSE
                     RITKNEFIDLVCKFTRWTMCIYWFEWILVNMGFNITFLQTGARWGTRIYIDPIFIILY
                     FFINLYAVIYKREGYNSTNKSIWNCIFSLLTFVIISQGRSGILYVVITSVIMLLISLK
                     PSKIIRFGILGIALIACLVSVTQIREVVISSFVESQSSDTGNIAYRIAEQDYFENKLE
                     GHELFGVGIPNNHDARAVEYSGKTIDFESKKYNPYYLEDLGAFEIRYRFGIIAYALYI
                     VALAISIIDAGFRRDKSVAAFAGMAFMVFMALNFNLLAYITARPFGFMISLILIEISA
                     FNDEFIYIE"
     gene            15784..16914
                     /locus_tag="ACIZE9_001755"
     CDS             15784..16914
                     /locus_tag="ACIZE9_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WavE lipopolysaccharide synthesis family
                     protein"
                     /protein_id="HGC6093617.1"
                     /translation="MNLDRLKKIANMISPIIKVINAPLAYFSGKSDYMEKGILWPTVT
                     TYSNNSRKVIQYTTLPKNVDNMAQMQWAGESFEDICIVLQGPVLEDGDFTLNTVKMYN
                     KYYPKVKLVVSTWIGLSEETECKLREAGADVVLCKKPEKTGAYNINLQLTSAYEGVKM
                     AQKLGCSYALKTRTDQRLYANDVLKYFQTLLNIFPSSDCKVVNQRLIFTTYGKSFRYL
                     PFNLCDFLVYGETSELLKLYGIQRDNRASDFGKIIYTEEKEFNKKIFTLLEGKQGVSP
                     YDVFPDFDALYKKYMFAEYYIVYNYFLENIASNESYGDLMDAYYSYLKKYAVVADSEK
                     LLLYWPKYVQYNVKFENELDFYAKLDSKKWMDIYANYTPFSQ"
     gene            16940..18025
                     /locus_tag="ACIZE9_001756"
     CDS             16940..18025
                     /locus_tag="ACIZE9_001756"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HGC6093618.1"
                     /translation="MKIGIVTIVNGASFGNRLQNYATQKVLENNGYTVETINNCFDKE
                     STLSIVIKNAIYTLFKFIPHFKKSKSIWKRMYTFYQWDKQYIDYSHRKIDASKKNSFV
                     SIKNDYDYFLVGSDQIWNPKYAANKGFELLSFVPNEKRVSLSTSLGVPSIPSDLEKLY
                     VTEWNKFKSISVRENQAAKIIEDLTGTTAAVHIDPTLMLERSEWEAFQKKPDNIDENY
                     ILSFFLTNPPKDTVDVLDKVAKDLKIGVLTLDASWEYFQDITPNHFVYLISHARMIYT
                     DSFHCTVFSLLFGKPVVVFDRFDSEKMNSRLSTLLNKVNKAHFWVGKKADEAMIRAIA
                     SEPEYDIDKLMVSERECVKAYLKEYLQ"
     gene            18048..18863
                     /locus_tag="ACIZE9_001757"
     CDS             18048..18863
                     /locus_tag="ACIZE9_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093619.1"
                     /translation="MEHLSDCFGKMKIVTTSCAREYFKDDLDKSEYSCFVDSRAAMFF
                     AMGQALAKRRNVVVMLADELTSCYTALTECAFQQVDLIVFAFQTVRHEIDLASLKNCG
                     CNLINCSAQDDIDRVVSNTKGLNQTTVIKINMNCESDKDHICEYIDLPDIPVFFHGSL
                     YSPASKKKYEQYGQVSKYLGYLVGGKDAILIISHNEFLNDISVWINYYSFGEIQPKII
                     IFDSPNDYQYKWLCDLECSVAHSTNRFLSEDLALLQNNGISIVLRGDNYDIVS"
     gene            18847..20565
                     /locus_tag="ACIZE9_001758"
     CDS             18847..20565
                     /locus_tag="ACIZE9_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="HGC6093620.1"
                     /translation="MISSVKNVQILVSLLKQHNIKDIVISPGSRDFQLVHSVETDSFF
                     RTYTVVDERSAAFFANGLSMAIDKPVCVCCTSSTASSNYMAAAKDAFANGIQLVLLTA
                     DRDYRRLYQMEDQMIDQVDMYGAYVRSNVDIPIVKDSDDEWYATRKINEAILELNHGV
                     KGPVQINYQLMDLSAPFVETMPEYRKITRYQEDDLLSSVEIFKQKLLSKKRIMVLCGQ
                     QEENNLSALLEEFFIKYNTIIIKDNYSNIHGEHFIKTVLVTERMSVNAFIDYCPDLVI
                     TIGKHVWSFVKYTLRDKKLKFEHWRISEDGKIVDPFNKLTSVFQCSAEFFMETVTAGV
                     NSNNNLEYYNLWKTRLSKVCYPELVYSNFYAISELVKKIPDSALVHSSILNAARLYDF
                     VSDDKALLSFANLGADGIDGCLPTFLGQAEADKTRPAYLISGDLSFFYAMNSLCGDIP
                     DNAHIFLINNHSGSEFHTNFGKFYNGSLSVDKHIAAGHISNAKDWALENNIKYITADS
                     KESLKSGLDVFINTFDSPVLFEVFTDPDTDTSVLESFYSINKVITPKMYFRKALDIIK
                     KHLHIK"
     gene            20591..21427
                     /locus_tag="ACIZE9_001759"
     CDS             20591..21427
                     /locus_tag="ACIZE9_001759"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGC6093621.1"
                     /translation="MAIKSYIKRLLLYIRHGDPKINLDVSYLSEGAMLAGKTVIITGG
                     AKGLGFAIAKSFIAQGASVIITGRDMDSLNNAKCQLGDMCSIRAFDITDAKMYRTFFE
                     DAYETFGRIDILLNNAGISLHEDGFMSVTEKTWDKQMDTNLKGVYFFTQEFIKFVKEK
                     NQMQANIIMMSSERGLCGDSIPYGLSKAAINSLVVGLSKKYISEGIRVNGIAPGVTAT
                     AMTGISEKGNLYNPATIGYRYFLPEEVAQVALFLASSLSNCISGEIIACDQGQYLSRN
                     WG"
     gene            21432..22865
                     /locus_tag="ACIZE9_001760"
     CDS             21432..22865
                     /locus_tag="ACIZE9_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGC6093622.1"
                     /translation="MGILLKKYNSLSEPAKASIWFTLCNVLQKGILFLTTPIFTRMLS
                     TAEYGKYTIFISWYSIIAIFTTLNLSAGVYNKGLIKYENKYALTSSFLGLSSFISLCA
                     LMLYLPFRTVINGLLDLSTEFVILILIESIFEPAFLLWSVKERFDYKYQKLVLITVLM
                     AVLNPGLGIILILSFGEYAIWRVRAYVVVNVVVGMFIGIGILAKGKKLFDKEYWTYAL
                     RFNLPLIPHYLSMTLLNQVDRLMINSMVGASEAAIYSIAYTISSMMNIITTAINGSFI
                     PFTYKAIKDGVYEKIKSVANQLLVLIFVLCSFTMLFGPELIWVVGGEKYMDAVWIIPP
                     VAASVFFMFLYPLFGNIEFYYEKTNYVMFASCVGSIAKIISNYVSIPRFGYISAGYTT
                     LICYMLFSFAHYMFYKKILRENGIKEDMYNIKNIIFLSVLMIVLTIGMTILYFSTILR
                     YSIIIGLVIVAFLKRTQIMKILKNIKN"
     gene            22903..24543
                     /locus_tag="ACIZE9_001761"
     CDS             22903..24543
                     /locus_tag="ACIZE9_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HGC6093623.1"
                     /translation="MRLLIPSAKIVPEELHHLGKLPAIIYPINQKIVFDYLYDQYKDV
                     CSAIDIACYEKMDKVARRLDKYIKSKTVNIIQLKELGDLGRTIYDSLIGCDEPVIINF
                     ADTIINDNIYSLECDSFFYAEDYYSNTWTFFEEKDGDIISVLDKNELKEDDGKKHKLF
                     SGVFQIMDAQYFRECLRKALMSNVVNVNSFYQALQEYSKRYEFLSIKTNNWFDIGHAD
                     KYYNSKLEVKAREFNHISIDKDRSILRKISEDVEKFIGEIKWYLKLPAQVEYVRPRIF
                     EYSTSYINPYVSMEYYSYHTVHELFLYSDLTKKQWIDIFNRIRFVCSDFKRYSVSGDN
                     IQKSLKDMYLDKTFQRFNKLRKDPRFTEFFSSDIQINGVRYKSLDQIEALLSVSVPRE
                     LFDITQFNIIHGDLCFANIMVDNTFSFIKVIDPRGKFGDFDIYGDYRYELAKLFHSVD
                     GKYDFIIKDLFTIKYDPKKAIIDYIVQDRKRDYDLYEVFYSVFKDEIGSDLKKIELIE
                     ALLFLSMIPLHGESLNHQMAMLATGLEILGRVVPDIYC"
     gene            24631..25029
                     /locus_tag="ACIZE9_001762"
     CDS             24631..25029
                     /locus_tag="ACIZE9_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HGC6093624.1"
                     /translation="MFKDYAFVFDIDGTLCPIKKKDEKYEDLVPYANMVEKLRYYKEN
                     GAKITLFTSRNMNSYHGNLGVINANTAKILLAWLDKWEIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLSCTLDQLDEICKKSKLKSE"
     gene            25054..25770
                     /locus_tag="ACIZE9_001763"
     CDS             25054..25770
                     /locus_tag="ACIZE9_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC6093625.1"
                     /translation="MTVIITMAGLGSRFRKVGYTVPKFMIEAKGKTLFDWSLDSLLDY
                     NSHVEKYVFVVRKEDDATVFIKEHCSLYGIENVEVVEIDYMTDGQATTCMLAIPYCAP
                     DNAIMVYNIDTYVEPGEMKYVDISGEGHIPCFHADGDHWSFAKLNEYGDVVEVREKVR
                     ISNNCTLGAYYFSSAKLYASLYEEYYADERHLEKNEKYIAPLYNYMIEKGMKVTISIV
                     DKSKVHVLGTPEELDVFLNE"
     gene            25937..26629
                     /locus_tag="ACIZE9_001764"
     CDS             25937..26629
                     /locus_tag="ACIZE9_001764"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGC6093626.1"
                     /translation="MSTVAVPTFFIISSFLLCSGEVTSAKLSKQIYRVLKIYIIWSIL
                     YIPLVLKNWVQSDFSWKTDVLLYIRDFLFIGSYYHLWFLPALAFALWLVRKSQVSKIK
                     FLSGLLLCVVGLAFESYWFILSGNDSIEYIRYCYKSVFVTTRNGLFIGVPCVIIGQHL
                     AFHKNTILNKVFKYRNFILCAVLAIGCLLVGESFIINQIALREVNNLLIFSIPLALVV
                     VSVSLSLKIVHL"
     gene            27091..27447
                     /locus_tag="ACIZE9_001765"
     CDS             27091..27447
                     /locus_tag="ACIZE9_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093627.1"
                     /translation="MFLYLFAMAEEKSGLGLKKSFLVWIRYFRKSSSFRKMFLLVFFT
                     NMILFRTLMDRYVWLNPLSNVFGSWWIYSVNETTGEIRLTTECFENVILFIPFIILVM
                     WYKASEKDFGKIYQRL"
     gene            27474..27581
                     /locus_tag="ACIZE9_001766"
     CDS             27474..27581
                     /locus_tag="ACIZE9_001766"
                     /inference="COORDINATES: protein motif:HMM:NF016763.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093628.1"
                     /translation="MEFLQLFLHIETFQLSDLFYNTLGGGISGVIYYLS"
     gene            27641..29293
                     /locus_tag="ACIZE9_001767"
     CDS             27641..29293
                     /locus_tag="ACIZE9_001767"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGC6093629.1"
                     /translation="MDHNANYYHWLTNANAEIVEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLSDYLNKTYETPSVVVGYDSRIKSDVFAKVAADIF
                     AANGIQVHLWPELLPVPTVSFAIRYLKASAGVMITASHNPSKYNGYKVYGAGGCQITT
                     EAAAEILAEIEKLDIFADVKMGGDASRIASIQPEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEINEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKNAEGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PTDPVMVKTIVTMDLGERIASNYGVRTVDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLFDKLNEIYAKYGYCLNTLHSF
                     EFEGAAGFTKMQKIMVEFHKGLDMIGGKKVIETLDYSTGLNGLPKSDVLKYLLEGNCS
                     VVVRPSGTEPKLKTYISVSAESKEAAEVMEAVMAAELAEMFK"
     gene            29619..30002
                     /locus_tag="ACIZE9_001768"
     CDS             29619..30002
                     /locus_tag="ACIZE9_001768"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGC6093630.1"
                     /translation="MFAIVLMYYFQQSYLPAILNKAISIGDTGVHIFFFCSGFGLYLS
                     YLKKPITLGEFLQKRFIKIYIPYIIVITVSVLLPYMTQDLNAAKVYLSHVLLFKIFLP
                     VYEESLGPFGLFRQLFSSISYSYQL"
     gene            30108..30533
                     /locus_tag="ACIZE9_001769"
     CDS             30108..30533
                     /locus_tag="ACIZE9_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093631.1"
                     /translation="MGAALRNIFGNLLSACLVAEYLVKRKIVRFNNIFVIMASIVGIG
                     FAGISKIIGGLMESINDIFAFFGYGAIAILMYQVIPFRKIMPRISRYSYDIYLLHILV
                     FSTIHQIIPNLVLAAFVSIPITLVLSYYYSIMLYRLKLK"
     gene            complement(30688..>30825)
                     /locus_tag="ACIZE9_001770"
     CDS             complement(30688..>30825)
                     /locus_tag="ACIZE9_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HGC6093632.1"
                     /translation="GCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLG
                     Y"
BASE COUNT        10043 a         4497 c         6607 g         9678 t
ORIGIN      
        1 cgcatctaaa cgaaataata ttcctagaaa atcactggat tatcgaacac ctttggaagt
       61 atttttgagt tacgtaagta ttgatgatct gtctaactta atttgacaat taagaactat
      121 tattaattca atgttaattt ttttgttatt ttattttttg tgtaactttt aaaaacacct
      181 atgaaaatta aggaaataaa aatgaaatcg attaattgtt atcttattac tgttttattt
      241 acttttaaat cataaattgc cctagtcaag aaaacagttt gtggtatgat tatataggga
      301 aaacttgttt acaaatattt ctgtgaatat attagtttaa ttatgttttt taaaataaaa
      361 agctgtcatt tttatgtaag tgaattatat cttaatttat ctatcatcaa tacttaggag
      421 tgaatctatg gaaaagccat tcgtcaagtc attgactgct gtggcggtag gtgcaggtgc
      481 tattgcgatc tgtttgtttg gttaccatat caataatcag cggcaacatc agcaacggat
      541 caattatgca gaatctgcca tcaccaatca aaaagacacc ttgacttctt tatcaaaaga
      601 agtagacaag ctgtatagta caaaagaaaa aatttttcta aaccctgaaa taacagaaga
      661 aacaatcaca agtttgtcaa ataagctatc ctatgtcaaa ctttcagcag atgattacga
      721 catcaaagaa tcagaattgc ctaaagaagc tgttgcaatc caagatgaga agaaagcaat
      781 cgtgacacag ttagatagtg cagaatcaaa actgaagatc cagacagctg tcaacgattt
      841 gtttactaaa aatgtatcaa actggcagca agctgtagac gatgtcatca tcaaagaaaa
      901 ggtgacaagt gcagatgtcg ctcgtgtacg tgaaaatatg agctttttta aagatagtcc
      961 ttggaaaacg gttgttatgc aatatttagg attcgctgat actcagatcg cgcaagtcac
     1021 gcaactagat cagttattcg atacgatgtt gaaggatggt caagtgactg ccaccgctac
     1081 ttacgatcaa tatttgacgg cgctcagtca aatagagcag atccggaatg aaaaaataag
     1141 cgcagcatac gcaacaaaag cacaaactgt tgctcagcaa atgggctata gcaatataag
     1201 ttattgacag ttaaaacgtt gattcaagca aggttagcaa acggaggaaa ctatggcaag
     1261 acgaagaaga aaatcaagag ggaaaaaaat atttctgatt attttagcag ttcttatcgt
     1321 attagtatta gcaattgtag gagtaggagc aaaattatat ctggatctct cacattctat
     1381 tgagaaaact tacgaatcag tggaacgaac ccaaggagaa cgaacgaaac cagttgatct
     1441 ggacaaacaa gaatctttct ctgttctatt gatggggatt gatactggag atttaggtcg
     1501 ggtcgatcaa ggaagatcag atacgatgat ggttgccata gtcagtcctg aagacaaaca
     1561 gacaacgatc gtcagcattc ctcgtgatac gtatgtcgac atcgtaggtc gtgacacaaa
     1621 agacaagatc aaccacgctt acgcattcgg cggagctgcc atggcgatgg ataccgtaca
     1681 aaaatatgta gacatcccaa tcgatcacta tgtctctatc aatatgaaag ggctaaagga
     1741 acttgttgat gcagttggtg gtatcgaagt caataatgac ctcactttct cacaagatgg
     1801 ctatgacttt acaatcggta aaatcacatt gaacggggat caggcattat cttattctcg
     1861 tatgcgttat gaagatccaa atggtgacta tggtagacaa gagcgtcaaa gaaagatcgt
     1921 agaaggtgta gcaaaaaaag tattgagttt aaacggtgtc agcaactatc aatccgtttt
     1981 gaatgctcta gagtcgaata tgaaaacaga catgagcttt gatgaaatga aaaaaatcgc
     2041 tttagattat cgggaggcat ttggtacgat caagcaagat cagctgcaag gagaaggctt
     2101 tatgcaagat aatatctcct atcaaaaagt cagtgatcaa gaacttgatc gtgtaaaaaa
     2161 agaattaaaa gatcaaatga atctagagaa taaataggaa agtggagaaa aaatggaaga
     2221 gacaatcaac ttggaagaaa tttttgaaac attacgcaaa cacttggtaa caatcatcat
     2281 ctcaatgttt gctggcttgg ccatctcagg aatcgtaaca tttttcatct tgacaccaaa
     2341 atacagttca caagcacaat tgatcgtgac actgccacaa tcagacacag caaatgtcaa
     2401 tgatgtcaat acgaacctgc aaatgatcaa tacgtataaa gatatgatcg tcagtgattt
     2461 agtactaaat gaagtcaaag atcgtttaga aacagaagac aatgtgaaaa tgactgctgg
     2521 acaaatcaaa gatgcgatct ccgtcaatca gtcacaaaat tcacaaatgt tctcgatcca
     2581 ggcaataagc acgaatgcag tgactgctca acagatcgct aacacaactt cacaagtttt
     2641 ccaagagaac gcaaaagacg tgatgaatgt cgataaaatc tcgattattt caggtgcagt
     2701 tgccaatacg acacctgttt cgccaaataa taaattgaat ctagtgattg gcttagtatt
     2761 aggaatgatg gtaggcgtag gtctggcatt cttattcgaa ttacttgatc ggacagtgaa
     2821 agatgaaaaa tatgtgacgg atgcattagg attcccaatc ttaggaacag ttccagaaat
     2881 gtcagcgaaa gaattgaacg ctggtatccg taaaaaagga acagctcctg cacgaccaaa
     2941 agctacaaac gataaaacag ccccatcacg cagaagccgc tcaagagtct aggaggaaga
     3001 aaaatggcac gaacacagaa acaaaaagca gcacaaactc atgcagtcag tttgatcaca
     3061 ttaacaaacc catcttcacc aatcgccgaa caatatcgta cgatccggac gaatatccag
     3121 tttgcctccg cagctggtca gcaaatcaaa acgattgtcg tgacttcatc aggtcctgga
     3181 gaaggaaaat ccaccactgc agcaaacatt gcagtcgttt ttgctaaatc cggtcaacga
     3241 gttctactag tcgatgcaga tttacgtaaa cccgtcgtct ataagacatt ccagctgaac
     3301 aatgccaggg gattaagtac agcacttagt tcatcaggaa gtgtagcaga tgtaatccaa
     3361 cgaacgccag tcgagaactt gtcgattttg cctagtggac ctaagccacc caacccatca
     3421 gaattgttaa gttcgccaag aatggatcag atcctagacg aagcaagaca gttatttgac
     3481 gtggtgatat tcgatatgcc accagtagta gccgtaacag atgcacagat catgtcttca
     3541 aaaacggatg gcactttatt ggtcgtacgt gaaaatacat cacgtaaaga atcattgaat
     3601 aaagcaaaag aactgctaga gatggtacaa gcacgagttt taggtgttgt atacaacgga
     3661 gcagaacata gcaaagatgc tggttattac tacggaaatt aaggaataag aagagaggag
     3721 acaagagaaa tgatcgatct acattgccat atcctaccag gaatcgatga cggggcagaa
     3781 aacttagaag caagtattgc aatggctgaa aaagcgattc agcaaggcat cacgcatatt
     3841 ttatgcacac cacaccacaa taatggaaaa tacagcaatg aaaaatcaca agtcatttct
     3901 ctagtcgctt cgttacaagc cgaattagag aaaagacagt tgcctttgac gttattggaa
     3961 ggacaagaag tacgtattac cggaacgctc atcgaagaca tccaccgaga tgaaatttta
     4021 tttacagatt tagatgatac atatcttctg atcgaatttc cgacactgga agtgccgtta
     4081 tatgcagaat ggcttttttt tgagttgtta gaactaggaa agacaccagt gatcgtccat
     4141 ccagaacgca acgcgcattt tcgagaagac ccaaatcatt tgcttccgtt cctagatatg
     4201 ggatgtttgg cccaaattac tgcgccaagt tatgttggtg tatttggcaa agacattcag
     4261 aaaacagcca aaacaatggt caaacataat ctcgtgcaga tggctgcttc tgatgcccat
     4321 ggggtctcta agcgtacctt ttacttaaaa gagtgctatg agcagattgc taaggacttt
     4381 ggtaaggaaa aagtagtaca gatgaaacaa gtcgcaaagg atctgatcaa cggggatgaa
     4441 atcagttatc cagtctatga agaggtaaaa aagaagaagt ttggtttatt ttagttcttt
     4501 attcgtagat aaaaaggaaa tgaggagaga gggaaagtat ggaaagtgaa gatttattat
     4561 ctcgtattag tgaagtacat cctaatcaag tttggttgga taaagaaaaa gttgaaaaac
     4621 gatatatcta tttatttttt aaaagaatga ttgatattgt aggaagcatt attggtttga
     4681 ttttagcttc tcctttgatg ttctatgtag cttatcgaat cagaaaagaa gagccaggaa
     4741 gtccgatatt tttttgccat acacgtgttg gtaaaaatgg aaaaacattc aaaatgtata
     4801 aattccgttc gatgtgttta gatgctgaag aaaaattgga agaattactt gatcaaaatg
     4861 aaatagaagg tgcaatgttc aagatgaaag aagatccccg tgtcactaaa ataggtaaaa
     4921 ttatccgtgc caaaagcatt gatgaattgc cacagctatg gaatgtttta aaaggcgata
     4981 tgagtctaat tggtccacgg ccacctttgg agagggaagt agctgagtac acgagatatg
     5041 atcttcaacg cttgtatgta aaacctggtt gttcaggttt gtggcaagtt agtgatagaa
     5101 ataatgttag tttccataaa atggttgagt tggatttaga gtatattagt catcgaagtt
     5161 taatgtacga cttgaggttg attttaaaaa cgttttatgt tattgtcaag cccaatggag
     5221 catattagtt agggatagaa tgatggattg ttaataaaaa agattacaca tgttcatatt
     5281 atcgtttcaa aagtaataac tgtaattatg gagggtttga atcacttgta gaaaatctaa
     5341 aaaaagaaag gtgaatgggg caattcagta tcattattct tatataaaag aaaatattcg
     5401 aaattttggg atgataccac tcttaaatat aatgatctaa atgctttaat attggtatat
     5461 ccgatatagg aactgacgag ctatttagta tgatacaaaa gtatattgat agccattaat
     5521 aaattttcca aaaaataatg acagcacacc aatttttata atttagcttg ttgaatcggt
     5581 atgttcatgg gacggttcaa aaaaagaatc gaaaaaataa acggtaaaat tttagtgaat
     5641 cctatgtaat aaaatttgga tagatggaaa aacagcacat aaggaggctg agtttgttgt
     5701 catttctgct cctacaaact atggtagtga atgtgttatt gaattagtga tgtctgttac
     5761 ttcagagaca ttggggataa ttaacttcac tatacctgta gggtatacaa aaaatggaag
     5821 aaaaaatatt atcaatagat tttatttagt tcagaatttt tacgtggaag taaattattg
     5881 atgataatct ttatccaatt agaattatta tcgtaggatg tgatgatgat agccgtgaag
     5941 ttgttcaagt atttaccaat gtctacaacg cagaaaatta gtttgggttt ttcggattgg
     6001 aaaatttcaa tgtataaaat cataaatttg ctgtaaatag acagtttggg gtagtaatag
     6061 cccaataaat tgttcgataa actcatcttt ggggtgagaa tagctcaatc attgaatttc
     6121 aaacctgcct ttggggtggg attagaggtc aatatgtacc tacataatac tttttggaaa
     6181 atgatggtgt tgagaatgta agtacatttc aatgtgaaat tctaatatag ccccaaacga
     6241 ggtcaataaa aatgacctaa actcgtattt ctcccctaaa cgaggaggag atagatatga
     6301 aaattgaatg tgccggcgtt ggagttggct gcttttagta ggaatgaaca tggttcgatg
     6361 agaactgttt cagatagagt ggtcgatgat cacaggcctt taagtcgttt acagatgatg
     6421 agacttgtaa aaatagaggg acgaatggaa aaagatgatt ggtatagaag aaaagaaagg
     6481 tgttcagaaa gacgtaacaa ttgataggga agagaatctt aggggacata gattctattg
     6541 gattggacgc agagcacaag atatcttctt ctcggctcta gctttgattg cattgagccc
     6601 tgtgatgcta attacagcgc tcgccattgt gattgacgat cccggtggca gcccgatttt
     6661 tgtgcaggat agagttggaa gaaatggaaa gctgttcaag ttttataaat tccgatctat
     6721 gtgtgtagat gctgaagcaa aattagaagc cttgttggca caaaacgaga tggatggtcc
     6781 ggtcttcaag attaaagatg acccaagaat cacgagagtt ggtaaattta ttcgaaagac
     6841 aagtatcgat gagttacctc agctctggaa cattcttaaa ggtgatatga gtattattgg
     6901 acccagacct gctttaccga gagaggtgga acaatacggt gactacgaaa ggcagcggtt
     6961 gttcgtacag cctggtctta gttgctattg gcagattgct ccacatcgta atgaactgtc
     7021 ctttgaagaa tgggtggaac ttgatgtgaa gtacatcaat gaaagaagct ttatcacgga
     7081 ctggaagatt atcttcttga ctttacaggc tgtattattt ggatatggtg aatgattata
     7141 tatagtatta ggagttgaaa tatgtgaata ttattttatt atcgggtggt agcggtaggc
     7201 ggttatggcc gctgtccaac gatattcgta gcaaacaatt catcaaactg tttaaggatg
     7261 aaaatggcga atatgaatct atgattcaaa gagtttatcg ccagattaca actgttgacc
     7321 cagatgcaaa ggtcactatt gcaacaagta agtctcaggc tagtgcaatc cataatcagt
     7381 tgggagataa ggcttcgatt tgtgtagaac cttgtcgtag agatactttc cctgcaattt
     7441 tgttagctgc agcatatctt cacgatgaac ttggcgtagg tgatgatgaa agtgttgcgg
     7501 tttgtcctgt tgatccttat gtagataatt cctattacga aggcgttgaa gcccttgaga
     7561 agttggtgca gcagaatacg gctaatttga ctttgatggg tattgcacct acatatccta
     7621 gtgaaaagta cggttatatc atccctgaaa gttctaacga agtaagtact gttaaggagt
     7681 ttaaggaaaa acctgacaaa gcaacggcag agaaatattt agctcagaat gctgtttgga
     7741 atgccggtgt atttgcgttc aaacttggtt acctgttgga aaaagctcac gcaatggtgg
     7801 attttgaaga ttatcgtgat ttgtattcca agtatgagac tttaaccaag atcagctttg
     7861 actatgctgt ggtcgaaaaa gaaacgagca ttcaagtgat gcgttataac ggggattgga
     7921 aagatgtcgg aacttggaac atgatggctg aagttatggc tgataatatt aaggggaaag
     7981 ctgtaatgga tgatacctgt gttaatactc agattgtgaa tgagttgaat attcctattc
     8041 ttgctatggg ctgcaaagat atggtaattg cagcaagtgg cgatggaatt ctgatttctg
     8101 ataaagagcg cagtggctat atgaagccgt atgttgagaa aatcagtacg gaagtaatgt
     8161 ttgcagaaaa atcctggggt acatataccg ttatggacgt tcaggaaggc tccatgactg
     8221 ttaaagtttc tatgcaggcc ggacagaagt tgagctacca ctaccacaat tctcgcgatg
     8281 aagtttggac tgttgtagca ggacagggta aagcgattgt agatggtatg aagcagattc
     8341 ttcgtgcggg tgatgtggtg actattgccg caggatgtaa acatacaatc gaagccgtga
     8401 caaatctgga tattatcgaa gttcagattg gtgaaactat tagcgtcgct gacaagtata
     8461 agagttcttt gaactaaaag ttcgcgaggt agttattatg gagatactaa aatttcaacc
     8521 cgtgggtaaa gattatcttt ggggtggaga acggtttaag acggaatttg gaaaaaattg
     8581 acttaacacc attaagctta tacgtgggaa tgcttagttc atctagacga taactacgta
     8641 cggaaatatc aaatatgaag gacagaatgg taaaaccgag ttgtggtatg tattggaagc
     8701 tacaccgggg ggtgatttat gcttttgagt acgatgtaac agaagaaatg ttacgaaatg
     8761 ctgtgatgga cagatcactt gggaaacatt tatataaaga agaagtacac aagggagatc
     8821 ttttttatgt cagttcatgg tattggcgct ggagtattag tggctgaaat acaggaaagc
     8881 tcaaatgtta cctatcgagt ttacgattat gatcgagtag ataagaatga taataagtga
     8941 gaattgtact ttgaaaaagc gattcaggta atgaatatgg aagccacttt gaaattggag
     9001 aaaagaaata agctcattca tttttatcct ggtggctctc gtgaaatact gtgtagatgt
     9061 aaatactgtg agcccgaaag aatccaagta aagacggggt tttcgttctc ggtaaaagag
     9121 gaatcttttc aagttctttt atgtatatcg ggggacggac aagttgagtc ggcaaatggt
     9181 gttatgaaac tcattagatt tgtaaaaaag atattgtatg tttttgccaa cgaatattgg
     9241 aagatgttaa gtgttgagcg atgcggactt actgaaaatt agatggggat agagggagga
     9301 tatctaatgt cacgaatgag atttatgaac acagaaattg acaatcttac aatgggtgaa
     9361 gtattggtag aggttgaaaa aatgattcaa gataggagat gcggatatgt tgtaactccg
     9421 aatgtggatc acattgttca gttggaaaca ggaaaagagt tgcaagatgt ttataaaaac
     9481 gcatctttaa ttttgacgga tggtaaacca ttgatttgga tttcaaagtt ttataagaca
     9541 ccaataaaag aaaaaatatc gggatccgat atattttctt tactgtgcaa gatggctgca
     9601 gaaaagggat acacaatgta ttttttaggt gcggcagagg gcgttgcggc taaagcggca
     9661 gataacctga tgaaaagatt tccgggatta aatgttgtag gaacatactc tcctccttat
     9721 gggttcgaaa aagacgaaga tgaaatgttt aaaattgatt cccaaattaa acgagcaaat
     9781 ccagatatgc ttattgtggg tttgggttgc cctaaacagg aaaaatttat gttttataac
     9841 tgtgatagat tgggagtacc tgtgtctttt ggtctaggag ctagtttgga ctttgaggca
     9901 gggaatgtta aaagagcacc aaaatggatg tcagattatg gatttgagtg gctgtttaga
     9961 attactcagg accctaaaag aatggcaaaa cgatatttgg ttgatgattt aaaaatcttt
    10021 aaattagcac taaaatatcg gaaaaaataa actatattca atgaggacaa tgaagtatga
    10081 ttattacaaa aacacctttt cgcatgtctt tttttggcgg cggaacggat atggaagatt
    10141 attttcgaga aaatggcggt gcagtgcttt ccactacttt tgataagtac tgttatgtga
    10201 atgtgcgtca tttgcctaga ttttttgatt acagcacaga gttatcatat tctcgtactg
    10261 agagagtaac aaatattgaa gatatcgagc atcctgcaat tcgtaatgcg atgaaaatgc
    10321 tagatatgca tgaaattcgc cttacatatg aagcagatct tcctgcacgt tctggtctgg
    10381 gtacatctag ttcttttgcc gtaggtatgt tgaatgcttt ctatgctttg aagggcaagt
    10441 acgctgacaa gaagaaactc gttgataaag caatttatct tgaaagagtc ctttgtaatg
    10501 aagcaggcgg atggcaagat cagattgcag cagcttatgg tggctttaac cgaatcaatt
    10561 tcaactcaga tggctatgaa gtattgccta ttattattac gcctgagcgt aaaaagcagc
    10621 ttaacaacaa cttgatgatg ttctttactg gattcaccag attttcctct gatgttcaga
    10681 aggcaaataa tgtcagcggc acagaggaca aaagagtaag actgaaaaaa atgtatgagc
    10741 ttgtggatga agcagaagcg gttctgactg ataagaacag agatctagat gatttcggca
    10801 gactgcttga tctcacttgg agattgaaaa aggctaccgg tggtgcgatt agcactggaa
    10861 gtatcgatga actttatgaa aagggcatgg ctgctggtgc attgggcggt aaacttctcg
    10921 gagcaggtgg cggcggtttc ttggtttttt atgttcagcc tgaaaaacaa aatgctgtgc
    10981 gttcggcaat gagtaatttg atgtatattc cgtttgaatt tgaaaacggt ggaacacagg
    11041 ttattcatta cacaccggaa atgtatattc caaaataaag aaatcagcga ggataagaat
    11101 atgaaagttg ttattatggc aggcggtaag ggaactcgca tctcatcggt tgcaagcgat
    11161 attccaaagc ccatgattaa aattgaaaac aaaccggtat tggagcacga aatcgaatgt
    11221 ctgagagacc agggattcac agatattatt cttaccgtta gccatcttgg cgatatcatt
    11281 atgaactatt ttggcgatgg ttctggaatt tcaccagtta ctggtcagcc ctttgacgtt
    11341 aaaattgaat actttttgga gaaagagcca ttaggaaatg ccggtgcatt gtttcgttta
    11401 aaggataatt tgaccgaaga cttcctcctg ctgaatgcag atgcgatgtt tgacgttgat
    11461 ttcaaccgat ttgtagcata tcaccgtgaa aagggtggct tggtgacatt gtttactcac
    11521 cctaacagtc atccatatga cagcggtcta atcattgcag ataaggatgg ctctgtagac
    11581 agatggcttg taaaggaaga ttcccgtcca acttattacc gtaacagagt aaatgcggga
    11641 ctccatgtga ttagtcctgc tgttcttgat gtcgagataa acacacctaa gattgacttg
    11701 gaccgtcagt tattaaagcc gttggcagga accggaaaaa tgttctgcta tgatagtcca
    11761 gaatacgtaa aagacatggg tacccctgat cgttattatg ctgtctgtga agattttaag
    11821 gctggaagag tgaagggcaa aaatcttcag aataagcaga aagctgtttt ccttgatcgt
    11881 gatggaacga ttaatcaata tgttggcttt ctgcgtcata ttgatgagtt cgaactaatc
    11941 aagggtactg aagatgcagt gaaaaagatc aatgccgctg gatatctggc tattgtaata
    12001 acgaatcagc cagtaattgc aagaggtgaa gtttcttttg aagaattgga agagatccat
    12061 aacaaaatgg agacacttct tggatataag ggcgcttatt tggatgcagt ttattattgc
    12121 ccgcatcatc cacataaggg atatgaggaa gagcgcccag agctaaaatt cgattgtgaa
    12181 tgcagaaagc caaagcccgg aatgttaatt caggcagcta cggacttcaa catagatttg
    12241 agtcagtctt ggatgattgg cgatggcgag aatgatatta aagcgggcca agccgccggc
    12301 tgtaagactg cattggttgg cgagagtgag tatggacagg atatgaccat agcaaccctg
    12361 agtgaatttg cagataagat ctgctaaggg atgttttatc acgaaaggag agtataaaca
    12421 atgatagaca atagattaca gaaacacatt gatttgctga ttaaacgcta tcccactctt
    12481 gaagtaatca agcaggatat tgttgacgga tacctgatta tggaggaatg ctatttaaat
    12541 gatggcaagc tgctgatagc aggaaatggc ggatctgctg ctgattccga gcatattgcg
    12601 ggtgagctga tgaaaagctt taagacgcct cgccctgtta gtagggaatt tgcagataaa
    12661 ttgattgcgg ttgatcctgt aaagggttct gaattagcta agaatcttga atatggtttg
    12721 atggcgattc ctctcgttgc tcatgaagcg ctttccactg cgtatattaa tgatgttgat
    12781 ggcctaggtg ttttcgcaca gcagttgttt ggatttggaa gacctggcga tgtattcctt
    12841 ggtatttcga catccggcaa tagcaaaaat gtgataaatg caactgttgt tgctagagct
    12901 cttggtatga aagtaattgg cttaactgga gccaaaggtg gagaacttgc aagggtagca
    12961 gatgtttgtg ttaaagctcc tgaaacagaa acatatatga ttcaggagta ccatttgcca
    13021 atttaccact gttggtgtct aatgttggaa gataaatttt ttgggaatag ataaaatatc
    13081 taagcccata ttgaaaggat aaaattatga atgtactatt tataacaact caatttccat
    13141 atcctctaga taatggcgga aaaattggtg cgtacaacgg tatcagtgtt ttatctagag
    13201 actacgatgt gacggtattg tctttcaccg aagaaccgca gtatgttgaa gaaggtgtca
    13261 gtttttttcg agagaaattt aatagtgtaa aatttgaaaa tcctgtgata catgatgtac
    13321 acataagaaa taatccaatg aaattggtag aagctttagc aatagggtat tgtctacgcc
    13381 aaccttatat agtttcaaag ttttatgatt caaaaatgct gcagttaata gatgaaaaat
    13441 tttctaacaa tgcatattgg gatatcattt ttattgacta tctgaatatg caaagttatg
    13501 gtcaatacat acgggagaag tataaaacac aatttggtaa gtatatctta aaagaccaca
    13561 acatagaata tgatttagtc ctacaggaag ctgaatcaag tcgaggttta aaaaagaagt
    13621 tgcttcagtt agagtataag cgtactcgaa agtatgaaga ggccgcagta aatagggccg
    13681 attattgctt tagtgtgtgt gatgcaaata cggaagtact gaaaaagatt aatgacaaca
    13741 gttatacgat gcttccaact tatgaaatgc ttacaggggt gaaaaaaaat atagagaaga
    13801 acacgatcct atatttgggt aacctttctt ggaaatccaa tatgcaagga ttagtttggt
    13861 ttttagagtc aatttatcca aatattcaac aaagaattcc ggatgtaaaa atcacaattg
    13921 tcggtagcgg gccagttgga acagatttta gtaaatattc aggcgtggat tatcgtgggt
    13981 atgtaaaaga tatttcacac atttatgacg atcaagcggt gctaattgta cctttgttag
    14041 aaggtagtgg tataagaata aaaatattag aagcgttcaa taatgaaatt gcagttgtat
    14101 ctacattagt tgggtgtgat acgattggcg caaaagatgg aagtgagtta tttatagcag
    14161 ataacgaaaa agattttgca acggctgtag ttagactgct tgaagacatg aatttgaatg
    14221 aaaaagtaag aaagaatgca aaattattct taaaagaaaa atactcctta acggctagac
    14281 aagatgagtt tagtgcgata attaacagct aatatatata taagcttatc tgatgatgat
    14341 ttataggagg aaatatatgg agatggctga gagaaaggaa aagaaacttg gaaataagaa
    14401 tatcatatta ttttagaaaa ctcctgttat tttatgtttg tgtgattgtt gcggctatga
    14461 gttaccacct tacaggcaat tccaatgtag cgtcattaat tgctgtagta ggagtagttt
    14521 atgctattgt aaaggcgtgt aataacgagt atctggctat atgggttatg tttgtattag
    14581 gttctgatat atgggggata gtgccatata ttaacattgg tagtggtgtg ttgcattggt
    14641 cagattttaa tgttatagta gcgatatttc tctgcttgag attcatcaaa gttaaagcta
    14701 ggagtagata cgggattgtc tatagtgtaa tgcttatatt tattttgatt gcatgtgtgc
    14761 aatcgcattc aatctatgga caagatgtac atacaacgct cttaacagct agagaattgc
    14821 tagttgtaat atccttttgg ccgatagtaa aaatagtata ttcagaaaga ataactaaaa
    14881 atgaattcat tgatttagtg tgtaaattca caagatggac aatgtgtata tattggtttg
    14941 aatggattct tgttaatatg ggattcaata taaccttttt acagacaggt gcacgctggg
    15001 gtactagaat ctatatagat ccgatattta tcattttata tttctttata aatctatatg
    15061 cggttatata taaaagagag ggctataata gtacaaataa aagtatatgg aattgcattt
    15121 ttagtttact gacatttgtt ataatctcgc aaggcagaag tggtatatta tatgtagtaa
    15181 taacctcggt tattatgctt ttaatttcgc ttaaaccatc caagattatt agatttggta
    15241 tattaggaat tgccttaatt gcatgtctag tgtctgtgac ccaaattaga gaggtcgtta
    15301 tatcttcgtt tgtagagtct cagagcagtg acacaggtaa tatcgcatat agaattgctg
    15361 aacaagatta ttttgaaaat aaattagaag gtcatgaact atttggagtt ggtataccaa
    15421 acaatcatga tgccagagct gtagaatatt caggcaaaac aatagatttt gagtctaaaa
    15481 aatataatcc ctattatctt gaggacttag gcgcttttga aattcgttat agatttggta
    15541 taattgcata tgcgttatat atagttgctt tagctataag tattatagat gccggatttc
    15601 gaagagacaa atcggtcgcc gcatttgcgg gtatggcatt catggtgttt atggcgctta
    15661 attttaattt gctagcgtat attacagcaa gaccgttcgg atttatgatt tctttaattt
    15721 tgatagaaat atcggcattc aatgatgaat tcatatatat tgaataggta agggagagca
    15781 cagatgaatt tagatcgatt aaagaaaata gcaaatatga tttcaccaat cataaaagtg
    15841 ataaatgcgc cgttagcgta ttttagtggg aaatcagatt atatggagaa gggaatattg
    15901 tggcctactg taacaaccta ctccaataac agtagaaaag tgattcaata tacaacttta
    15961 cctaaaaacg tagacaacat ggctcaaatg caatgggctg gggaaagttt tgaggacata
    16021 tgtatagttc ttcaaggtcc agtattagaa gacggtgatt ttacactaaa taccgttaaa
    16081 atgtataata aatactatcc taaagtaaaa cttgtagtgt ctacttggat aggattatct
    16141 gaagagacag aatgcaagtt gcgtgaagct ggtgcagatg ttgtattatg caagaaacct
    16201 gaaaaaacag gtgcgtacaa tattaatcta caacttactt ctgcatacga aggcgtaaaa
    16261 atggcgcaaa aactggggtg tagttatgcg ctgaaaacgc gaactgatca aagactatat
    16321 gcaaatgatg tactaaagta tttccaaaca ttattgaata tttttccatc ttcggactgt
    16381 aaagtagtga atcagcgatt aatatttacg acttatggaa aatcatttag atatcttccg
    16441 tttaatttat gtgatttttt ggtatacgga gaaactagtg aattattaaa attatatggt
    16501 attcaaagag ataaccgagc atcagacttt gggaaaatta tttatactga ggaaaaagag
    16561 tttaataaaa agatatttac actactagaa ggaaaacaag gtgtatctcc atatgatgtt
    16621 tttccagatt ttgatgcact atataaaaaa tatatgtttg cagaatacta tattgtgtat
    16681 aattatttcc tggaaaatat tgcaagtaat gaatcttatg gtgacttaat ggatgcctat
    16741 tatagttatt taaagaaata tgcagttgtt gctgattcag aaaaattgtt actatattgg
    16801 ccgaaatatg ttcaatataa tgttaagttc gaaaatgaac ttgatttcta tgcgaagttg
    16861 gattcaaaaa aatggatgga tatttatgct aattatacac cttttagtca gtgattatat
    16921 ggaaaggatg aggtgaataa tgaaaatcgg aatagtgact attgttaatg gggcaagttt
    16981 tggtaacaga ttacaaaatt atgcgactca aaaagtgttg gaaaataacg gctatacagt
    17041 tgagacaatt aataattgtt ttgacaaaga aagtacccta tccattgtta tcaaaaacgc
    17101 tatttataca ttatttaagt ttataccgca tttcaaaaag tcaaaaagta tctggaaaag
    17161 aatgtataca ttttatcaat gggacaagca gtatatagat tattctcatc gtaaaattga
    17221 tgcatctaaa aaaaacagct ttgtgagtat aaagaatgat tatgactatt tcttggttgg
    17281 tagcgatcaa atttggaatc caaaatatgc agccaataag ggatttgaac ttttatcatt
    17341 tgttccaaat gaaaaaagag tttcattatc aaccagtttg ggagttccat ctataccaag
    17401 tgatttagaa aaattatatg tgacagagtg gaataagttt aaatcaatat cggtacgtga
    17461 aaatcaagcg gcaaaaataa ttgaggactt gacaggcaca actgcggctg ttcacattga
    17521 cccaacttta atgttggagc gttcggaatg ggaagccttt caaaaaaaac cagacaatat
    17581 tgatgaaaat tacatcttgt cgtttttctt aactaatccg cctaaggata ctgttgatgt
    17641 attagataag gtcgctaaag atttgaaaat aggtgttctc accttagatg cgtcttggga
    17701 atattttcaa gatattactc cgaatcattt tgtttatttg atttcacatg caagaatgat
    17761 ttatacagat tcattccact gcacagtttt ttcattgcta tttggaaaac cggttgtggt
    17821 atttgaccgt tttgatagtg aaaaaatgaa ttctaggtta agtacattgt taaataaagt
    17881 aaataaagca catttttggg taggaaaaaa agctgatgaa gcaatgattc gtgcaatagc
    17941 atctgaacct gaatatgaca tagataagct gatggtatca gagagggaat gtgtaaaagc
    18001 ttatcttaaa gagtatttac agtaaaattt tgaaatggga tgaaaatatg gagcatttaa
    18061 gtgattgttt tggtaaaatg aagattgtta cgacttcatg cgcaagagaa tattttaagg
    18121 atgatttgga taaatcagag tattcatgtt ttgttgattc tcgagcagct atgtttttcg
    18181 caatgggaca agctttagct aaaagaagga atgtagttgt aatgcttgct gatgaattga
    18241 catcgtgtta tacggcacta acagaatgtg catttcaaca agttgattta attgtgtttg
    18301 cttttcagac agtcagacat gaaattgatt tagcatcttt gaagaattgt ggttgcaatc
    18361 taattaactg tagcgcccaa gacgatattg atagagttgt gtccaacact aaggggttaa
    18421 atcagacaac agtaattaaa atcaatatga attgtgagtc ggataaagat catatatgtg
    18481 agtatataga cctgccagac atacctgttt ttttccacgg tagcttatac tcacctgcaa
    18541 gtaaaaagaa atatgagcag tatggacagg tatcgaagta tttaggctat ctcgtggggg
    18601 gaaaagatgc aatactcata atttctcaca atgagttttt aaacgatatc agtgtatgga
    18661 ttaattatta ttcttttgga gaaattcaac ccaaaattat tatatttgac agtccgaatg
    18721 actatcaata taaatggctg tgtgacttag aatgcagtgt agctcattca accaaccgat
    18781 ttttgtctga ggatttagcc ttattgcaaa ataacggaat ttccattgtg ttaagaggtg
    18841 ataattatga tatcgtcagt taaaaatgtt caaattttag tatctttatt aaaacagcat
    18901 aatattaaag atatagttat ctcgccaggt agtagagatt ttcaattggt gcatagtgta
    18961 gaaacagaca gtttttttag aacctatacg gttgtagatg agcgcagtgc tgcctttttt
    19021 gctaatggac tttctatggc gattgataag cccgtgtgtg tatgttgtac ttcttcaact
    19081 gcctcttcaa attatatggc ggcagctaaa gatgcttttg ctaatggcat ccaacttgta
    19141 cttcttactg ctgatagaga ttaccgccgc ttatatcaga tggaagatca gatgattgat
    19201 caggtagata tgtatggggc ttatgtgcgt tctaacgttg atattcctat tgttaaggat
    19261 tctgatgatg aatggtatgc taccagaaaa ataaatgaag caatattgga gttaaatcat
    19321 ggcgttaagg gtcccgtgca gattaattat caattaatgg atttaagtgc gccgtttgtt
    19381 gagaccatgc cagagtatcg taaaattaca agatatcaag aggatgattt actgtcatca
    19441 gtagagattt ttaaacagaa actattatca aaaaagagaa taatggtttt atgtggacag
    19501 caggaagaaa ataatttaag tgccttattg gaagagttct ttattaaata taatacaatt
    19561 ataatcaagg ataactattc taatatacac ggtgaacact ttattaagac tgttctagta
    19621 acagaaagaa tgagtgtaaa tgcatttatt gattattgcc cagatttggt aataactatt
    19681 ggtaaacatg tatggtcttt tgtgaaatat actcttagag ataaaaagct taaatttgag
    19741 cattggcgga tatctgagga tggtaagatt gttgatccgt tcaacaagct aacatctgtc
    19801 tttcagtgct cagcggaatt ttttatggag actgtcactg ctggtgtgaa tagcaataat
    19861 aatcttgagt attataatct atggaagaca agattatcaa aagtttgcta tccagagtta
    19921 gtctatagca atttttatgc aatttcagaa ctagtaaaaa aaattccaga tagtgcatta
    19981 gttcattcta gtattttaaa tgcggctaga ttgtatgact ttgtatctga tgataaagca
    20041 ttactcagtt ttgctaattt aggggctgat ggtattgatg gttgtttacc aacattttta
    20101 ggtcaggcag aagcagataa aactcgacct gcgtatttaa tttcaggaga cttgagtttc
    20161 ttttatgcta tgaatagttt atgtggtgac attccagata atgcacatat tttccttatt
    20221 aacaatcatt ctggaagtga attccataca aattttggta agttttacaa cggatcatta
    20281 agtgttgata agcatatagc tgcaggacat atttcaaacg caaaggattg ggcattagaa
    20341 aataatataa aatacattac tgcggattct aaggaaagtc tcaaatcggg gttggatgta
    20401 tttattaata catttgacag tcctgtttta tttgaggtct ttacagatcc ggatacggat
    20461 acgtctgttc tggaatcttt ttatagtata aataaggtaa tcacaccaaa aatgtatttt
    20521 agaaaggcgt tagatattat aaaaaagcat ttacacatta agtagatgtt tattgcgagg
    20581 tgaaacaaat atggcaataa aatcttatat taaacggtta ttgctttata tccgtcatgg
    20641 agatcccaaa ataaatttag atgtgagtta tttatctgaa ggtgcaatgc ttgctggtaa
    20701 gactgtgata attacgggtg gtgcaaaagg acttggtttt gcaattgcaa aatcatttat
    20761 agctcaaggc gcaagcgtta ttattacagg aagagacatg gattcgttga ataatgctaa
    20821 atgtcagctt ggagatatgt gttctatcag ggcgtttgat ataactgatg ctaaaatgta
    20881 tcgaacgttt tttgaagatg catacgagac ctttggacgt attgatatac tgcttaataa
    20941 tgctgggatc tcgttacacg aagatggatt tatgagtgtt actgagaaaa cttgggataa
    21001 gcaaatggat acaaatttga aaggtgttta tttctttaca caggaattta ttaagtttgt
    21061 taaagaaaag aatcaaatgc aagcaaatat tattatgatg tcctcagaaa gaggcttgtg
    21121 tggtgatagt attccgtatg gattatcaaa ggctgcaatt aactctttag ttgtaggctt
    21181 gtctaagaaa tatatttctg agggaattag ggttaatggt attgctcctg gagtaactgc
    21241 aaccgctatg actggtattt ctgaaaaggg taatttgtat aatcctgcaa cgatcggtta
    21301 tagatatttt ctcccagaag aagttgctca agttgctttg tttttggcaa gtagtctttc
    21361 aaactgtatc agtggtgaaa tcatagcctg tgaccagggg caatatttaa gtcgaaattg
    21421 ggggtaataa cttgggaata ttattaaaaa aatataatag ccttagtgag cctgcaaaag
    21481 catctatttg gtttacactt tgtaatgtgt tgcaaaaagg aattctattt ttgactacac
    21541 ctatttttac aagaatgctt tcaactgcag aatatggtaa gtatacgatt tttatatcgt
    21601 ggtattctat tatagcaatt ttcacaacgt tgaatttatc tgcaggtgtc tataataaag
    21661 gactaattaa atacgagaat aaatatgcat taacctcgtc atttttagga ttatcgtcat
    21721 ttatttccct ttgtgcattg atgctatacc ttccatttag aacggttata aatgggctac
    21781 tggatttatc gacggagttt gtcatattga ttcttattga atcaatattt gagccggctt
    21841 ttttgctttg gtcagttaag gaacgatttg attacaagta tcaaaaacta gtactcatca
    21901 cagttcttat ggctgtttta aatccaggtc tcggtattat attaatctta tcatttgggg
    21961 agtatgctat ttggagagta cgagcttatg tcgtggtaaa tgttgtagtg gggatgttta
    22021 ttggcatagg aatactggct aagggtaaga aattatttga taaagagtac tggacatatg
    22081 cgctcagatt taatttgcca ttaataccac attatttatc aatgacattg ctgaatcagg
    22141 ttgatcgcct tatgataaat agtatggttg gagctagcga ggctgcgatt tatagtatcg
    22201 cttacactat atctagtatg atgaatatca taacaacagc tataaacggt tcttttattc
    22261 cttttacata caaagcaatt aaagatggcg tgtatgaaaa aattaaatcc gttgctaatc
    22321 aactattagt gttgattttt gtcttgtgtt cgtttactat gctgttcggg ccagaattga
    22381 tttgggttgt cggaggagaa aaatatatgg atgctgtttg gattattcct ccagttgcgg
    22441 catcagtatt tttcatgttt ttatatccgc tttttggcaa tattgaattt tactatgaaa
    22501 agacaaacta cgtaatgttt gcatcttgtg tgggctctat cgcaaaaatt atttcaaact
    22561 atgttagtat tccccgtttt ggatatattt cggctggtta cacgacattg atttgctata
    22621 tgttgttttc ctttgcccac tacatgtttt ataaaaaaat tcttagagaa aatggtataa
    22681 aagaagatat gtataatatt aaaaatatta tatttctttc tgtcttaatg attgtgttaa
    22741 ctattggtat gacaatatta tacttttcta caattctaag atatagtatt attattggat
    22801 tagttattgt ggcttttctt aaaaggacgc aaataatgaa aatccttaaa aatataaaaa
    22861 attaacaagc aaatcttggg aatggaacgg aggcacggtg aaatgagatt attgattcca
    22921 tctgctaaga ttgtaccgga agaacttcac catcttggaa aacttcctgc aattatctat
    22981 ccgattaatc aaaaaattgt atttgattat ttatatgatc aatataaaga tgtatgttct
    23041 gctatcgata ttgcctgtta cgaaaagatg gataaggtag caagacgatt agataagtat
    23101 attaaatcta aaacagtaaa tattattcag cttaaagagt taggggatct tggaagaact
    23161 atatatgatt ctctaatagg atgtgacgag cctgttatta ttaattttgc tgataccatt
    23221 atcaatgata atatatattc cttggaatgt gacagctttt tctatgctga agactattat
    23281 agtaatactt ggacattctt tgaagaaaaa gacggagata ttatttctgt tttagataag
    23341 aacgagttaa aagaagatga tggaaagaag cacaaactgt tttctggtgt atttcaaatt
    23401 atggatgccc agtattttag agagtgtttg cgtaaagctt tgatgtcaaa tgtagtaaat
    23461 gtgaatagtt tttatcaagc tttacaagag tatagcaaac gatatgaatt tctctctatt
    23521 aaaacaaata attggtttga cattggacat gcagataaat attataattc caaattggaa
    23581 gttaaggcaa gagaatttaa ccacatttca attgataaag atcgtagcat cctgagaaaa
    23641 attagtgaag atgttgaaaa atttatcgga gaaattaagt ggtatcttaa gttgccagca
    23701 caggtagaat atgtgagacc tagaatattc gaatattcta cttcgtatat taatccatat
    23761 gtaagtatgg aatactattc gtatcatact gttcacgagt tatttctcta tagtgactta
    23821 acaaaaaaac aatggataga tatctttaat agaatacgat ttgtatgctc agactttaag
    23881 agatactctg tttcagggga taatattcaa aagtcattga aagatatgta tctcgataaa
    23941 acatttcaga gattcaataa gctcagaaag gacccccggt tcacagaatt cttttcttct
    24001 gatattcaaa taaatggagt cagatataaa tctttggacc agatagaagc tttattgagc
    24061 gtaagtgttc caagagaatt gtttgacatt acgcaattta atattattca tggtgactta
    24121 tgctttgcca atattatggt agataacaca ttttcgttca ttaaagtcat agatccgcga
    24181 ggtaagtttg gagattttga tatttatggt gattatagat atgaactggc aaaattgttt
    24241 catagtgttg atggaaaata tgactttata attaaggact tgtttacaat aaaatatgat
    24301 ccaaagaagg caatcataga ctatattgtt caagatcgta aacgagatta tgatttatat
    24361 gaagtatttt actctgtctt caaagatgaa ataggttctg atttgaaaaa aattgaactt
    24421 attgaggctt tgctgttttt aagtatgatt cctttgcatg gagaaagctt aaaccatcag
    24481 atggctatgt tagcaactgg tttggaaatt ttaggacgag ttgtcccgga tatttattgt
    24541 taatgctttg agctattgtt tttctatttg atcagtgtaa agccgggcat ataaattgcc
    24601 tggctaaaat aaaggagatg tcttagttat atgtttaaag attacgcatt tgtttttgat
    24661 attgatggaa ctttgtgccc catcaaaaag aaagatgaga aatatgaaga tttagttccg
    24721 tatgctaata tggtggagaa gttgcgatac tataaggaga acggagcaaa gattacactg
    24781 ttcacatctc gcaatatgaa ttcttatcat ggtaatttag gtgtgatcaa tgcaaatact
    24841 gcaaaaatct tgttggcttg gctagataag tgggagattc cgtatgatga aattctttat
    24901 ggaaagcctt ggccaggcca taaagggttt tatgttgatg atcgcacagt tcgtccggat
    24961 gaatttttat cgtgtaccct ggatcagctc gatgagattt gcaaaaaatc caaattgaaa
    25021 tctgagtaaa ggagacttta taaagtgaat aagatgacgg ttattattac aatggctggt
    25081 cttggcagtc gctttcgtaa agttggctac actgtgccca aatttatgat tgaagcaaaa
    25141 ggtaaaacct tatttgattg gtccttagac agcttgcttg attataattc acatgtagaa
    25201 aagtatgttt ttgttgtgcg taaggaagat gatgctactg tttttatcaa agaacattgc
    25261 agtctgtatg gaattgaaaa tgtcgaggta gttgaaattg actatatgac tgatggacaa
    25321 gccactacat gtatgcttgc aattccttat tgcgcacctg ataatgcaat tatggtttat
    25381 aacatagata catatgttga gccaggtgag atgaaatacg ttgatatttc tggagaagga
    25441 catattccgt gtttccatgc ggacggtgat cattggagtt ttgccaagtt gaacgaatat
    25501 ggtgatgtag tagaagtaag agaaaaagtt agaatttcta acaattgtac tttaggtgca
    25561 tattattttt cttctgcaaa attatatgca tcactctacg aagaatatta tgcagatgaa
    25621 aggcatctgg aaaagaatga gaaatatatt gcgccgctat ataattatat gatagagaag
    25681 ggcatgaagg taaccattag tatagtagat aaatcaaaag ttcacgtact cggtactcca
    25741 gaagagctcg atgtgttctt aaatgaatag ggaaaatata atcatagaaa atgttaatta
    25801 taaagctgcg tgtgtggggg agtactattc gatagatatt ctaaaaatac taatggctat
    25861 tttagttgtt gttcgtcatt taggtcaaaa ctatttagct ccagattaag catttagtat
    25921 tggtattgtt gcaggactga gtacggttgc cgttcctact tttttcatca tcagttcctt
    25981 tttgttgtgt agtggtgaag ttacatccgc taaattatct aaacaaatct acagagtact
    26041 taaaatttac attatttggt ctatattata tattccatta gtattaaaga attgggtaca
    26101 gtcagatttt agctggaaaa cagatgtatt attgtatatc agagattttc tgtttattgg
    26161 tagttactat cacctgtggt tcttgcctgc actggctttt gctctatggt tagtacgcaa
    26221 aagccaggtt tctaaaataa agtttctcag tggtttgttg ctatgcgtag taggtttagc
    26281 atttgaatct tattggttta tattatctgg gaatgattcc atcgagtata ttagatattg
    26341 ttataaaagc gtgtttgtaa caactcgtaa tggattattt ataggtgtac catgcgtcat
    26401 tattgggcaa cacttagcct tccacaaaaa cactatactt aataaggtct ttaaataccg
    26461 taattttatc ttatgtgctg ttttagctat aggatgctta ttagttggtg aaagtttcat
    26521 cataaatcaa atagctttgc gagaagtcaa taatttgtta atattttcca ttccattagc
    26581 actggtagtt gtatcagtat cactgagcct aaagatagta catttataaa aataacagta
    26641 catctgcgaa gaattagtac gttattattt tgtttacatc cgtatataat agctgcttta
    26701 aattttattt tcccaaaatt ggggattaca aattcattaa tagaaatgac ttgtggaatg
    26761 ataataattt taatttctac agtttttgtg tatgcgtgta gtgtgaaatt taccttgctg
    26821 aaaaaattat attagattag taactggtac atgtaaattt gttgaaatta tagcagcata
    26881 gagataggaa ttctgttgag ttttattttc gctggccgag gttattcatg ttagagtggg
    26941 tacctccttt tacgaaacct tcttgatggt actcatttag cgcatgatga aaggagagtt
    27001 tatgaagaaa atcatatctt ctattttggt taatgtgtta tctgcattgt atcaaatatt
    27061 tgggtttcga ttttaattgc agttttggct atgtttttat acttgtttgc gatggctgag
    27121 gagaaatcag gattaggttt gaaaaaatct tttcttgtct ggattcggta tttcagaaaa
    27181 tcaagctcat ttagaaaaat gtttttgctt gtgtttttta caaatatgat tctttttaga
    27241 acactgatgg atagatatgt ttggctaaat cctttgtcta atgtgtttgg tagttggtgg
    27301 atttactctg tgaatgaaac gacaggggag attagattaa ctacagaatg ttttgaaaat
    27361 gttattctgt ttattccatt tataattcta gtaatgtggt ataaggcttc agaaaaagat
    27421 tttggaaaaa tttatcagag attataaaat ttgttttttt atgttcgtgt cttatagagt
    27481 ttttgcagtt atttttacac atagagacat tccaattgtc agatttattt tataatactt
    27541 tgggtggcgg cattagtggg gttatatatt atttgagctg atatattcat cctaacctta
    27601 aaaataaatg agcagaattt taaaagattg gagagattct atggatcata atgcaaatta
    27661 ttatcattgg cttacaaatg ccaatgcaga aattgtagag gaactgcggt catattccga
    27721 gaaggacatt gaggactcct tctataaaaa tctgtccttt ggtaccggtg gtctgcgtgg
    27781 caccattggt gcaggcacta atcgtatgaa cgtacacacc gtaggtaagg caagccaggg
    27841 actgtcagac tatctgaata agacctatga aaccccttct gtcgtcgtgg gctatgattc
    27901 ccgaatcaag tccgatgtat ttgcaaaggt tgccgcggac atctttgctg caaacggtat
    27961 tcaggtgcat ctgtggccgg agctgctgcc tgtgcctacc gtatcctttg ctatccgtta
    28021 tctgaaggct tctgccggtg ttatgatcac cgcatcccat aatccttcca agtataacgg
    28081 atataaggtc tatggcgcag gcggctgcca gatcaccacc gaggctgccg ctgagattct
    28141 ggctgaaatt gaaaagctgg atatttttgc agatgtgaaa atgggcggcg acgcttccag
    28201 aatcgcttct atccagccag aggttctgac tgctttcatt gaagaagtaa agggccagtc
    28261 ggttctgttt ggcgaagaag tggacaagaa tgttgctatc gtgtattctc ctttgaatgg
    28321 taccggtctg gtgcctgtta cccgtactct ggcagaaatg ggctacagca atgtgaccgt
    28381 tgtcgaagag cagcgtctgc cagacggtaa tttcccgacc tgtccttatc cgaatccgga
    28441 aattaatgaa gctatgtctc tgggcatgga gtatgccaag aagtataatg ctgatctgct
    28501 gctggctacc gaccctgact gcgaccgtgt gggtatcgcc gtgaagaatg cagaagggga
    28561 ttatgtcctg ctgtccggta acgaaactgg tctgttgctt ctggactaca tatgctctca
    28621 gagaattaag cacggcaaga tgcccactga ccctgtgatg gtcaagacca tcgtgactat
    28681 ggatctgggc gagcggatcg cttccaacta tggcgtgcgt actgtcgatg tgttgaccgg
    28741 cttcaagttc atcggcgaac agattggtat gctggaaaag gcaggcaagg tggacagcta
    28801 tattttcggc tttgaggaat cctacggcta tctatccggc agctatgtcc gtgacaagga
    28861 tggtgtcaac gccgcttatc tgatctgcga gatgttctct tactacaaga ctcagggtat
    28921 cagtctgttt gataagctga acgagattta tgctaagtat ggctactgtt tgaacaccct
    28981 gcattccttt gagtttgagg gtgcggcagg ttttaccaag atgcagaaaa ttatggttga
    29041 attccataaa ggtcttgata tgattggagg taagaaggtc attgaaacct tggattacag
    29101 cacgggactg aatggcctgc cgaagtctga tgttctcaaa tatctgctgg agggcaactg
    29161 ctctgtagtg gttcggcctt ccggcactga gccgaagctg aagacctata tcagcgttag
    29221 cgcagaaagc aaggaagctg ccgaagtaat ggaagctgtt atggctgctg aactggctga
    29281 aatgtttaag taatactatg aaaaagatct gagtgtcaat gtccgaagta gcaacatcta
    29341 tgtttaataa aaatttcctg ctttacggtt ctgtttacat aattgaggta aaggggccga
    29401 ctgtgtggat cgaaaaggca aagaagtgtt aacagagaca cagcagcctg atgaagcacc
    29461 gatcaaagca gtaagggaga aataagagat attagagttt taataatgta ttcagcaata
    29521 gagatgaaag gagtagaata tgaataaaac tattgaaata ataaaatgag ggggaaagaa
    29581 ataaacgtga tattattagt tttgagaagg cgttttcaat attcgctatt gtattgatgt
    29641 actattttca gcaatcgtat ttgccagcaa tactgaacaa agcaatatct attggtgata
    29701 caggagtgca tatattcttc ttttgctcag gttttgggct atatctgtca tatttaaaaa
    29761 agcctattac attgggtgaa tttttacaga aacgatttat caagatttat attccgtata
    29821 ttatcgtaat tacggtatca gtgttactac cttatatgac acaagattta aatgctgcaa
    29881 aagtatattt gtctcatgtt ttgttattta aaatttttct accagtatat gaggagtcac
    29941 tgggtccctt tggtttattt cgacaattat tcagttctat ttcttattca taccaattgt
    30001 aaaactatag agaaaaatag gaatgaaatg attgcttgtt gcaagctgag ttattagtat
    30061 ctgggctatt atgatgtttc atacaggata tggaagcata cgagttcttg ggagctgctt
    30121 tgcgcaatat atttgggaat ttactttcgg catgtttggt tgcagagtat ttagtgaaaa
    30181 gaaaaatagt aagatttaat aatatattcg tgattatggc gtccattgtt ggaattggtt
    30241 ttgctggtat atcgaaaatt attggtggac tgatggagtc tattaatgat atttttgcat
    30301 tcttcggtta cggtgcaatt gcaattttaa tgtatcaagt tattccattt agaaagataa
    30361 tgcctaggat ttcaagatac tcatatgata tatatctact ccatattctt gtatttagta
    30421 cgattcatca aattatccct aacttggttt tggcggcatt tgtttccatt cctataacgt
    30481 tggtgttgtc atattattat agtattatgt tatatagact taaattaaaa tgatagcata
    30541 attgtcgcct ctaccgggcg gttgccatcc tgattaacag cctccacgcg gcggatggtg
    30601 ggcacttagg tagttcgtaa cctagtggta gatggttggt aaaaaggaga taaaactaaa
    30661 tgattacacc cgtggtgcta gttaatttta atatcctaaa gaatatctca aagttccttc
    30721 aaaacgtcgt tgtgctcgac ttaatagaac actgtaagcc agtaatatgc tttcaaatct
    30781 actctctagc cctttaacag aacgtgagtt gaaattttga caacc
//
LOCUS       DBBGSP010000033        30404 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000033 DBBGSP010000000
VERSION     DBBGSP010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.033"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(1237..1902)
                     /locus_tag="ACIZE9_001771"
     CDS             complement(1237..1902)
                     /locus_tag="ACIZE9_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093633.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2028..4064
                     /locus_tag="ACIZE9_001772"
     CDS             2028..4064
                     /locus_tag="ACIZE9_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGC6093634.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4068..4706
                     /locus_tag="ACIZE9_001773"
     CDS             4068..4706
                     /locus_tag="ACIZE9_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093635.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4734..5162
                     /locus_tag="ACIZE9_001774"
     CDS             4734..5162
                     /locus_tag="ACIZE9_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093636.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5619..6530
                     /locus_tag="ACIZE9_001775"
     CDS             5619..6530
                     /locus_tag="ACIZE9_001775"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC6093637.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            6747..7184
                     /locus_tag="ACIZE9_001776"
     CDS             6747..7184
                     /locus_tag="ACIZE9_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093638.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            7279..8163
                     /locus_tag="ACIZE9_001777"
     CDS             7279..8163
                     /locus_tag="ACIZE9_001777"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGC6093639.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            8387..11554
                     /locus_tag="ACIZE9_001778"
     CDS             8387..11554
                     /locus_tag="ACIZE9_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HGC6093640.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            11622..12119
                     /locus_tag="ACIZE9_001779"
     CDS             11622..12119
                     /locus_tag="ACIZE9_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HGC6093641.1"
                     /translation="MILLLGFILWQTPVHASEFNFAVDFELPANQIDKNKTYINVRME
                     PGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAK
                     TVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQV
                     KAILI"
     gene            12138..12602
                     /locus_tag="ACIZE9_001780"
                     /pseudo
     CDS             12138..12602
                     /locus_tag="ACIZE9_001780"
                     /inference="COORDINATES: protein motif:HMM:NF023225.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
     gene            12599..13357
                     /locus_tag="ACIZE9_001781"
     CDS             12599..13357
                     /locus_tag="ACIZE9_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HGC6093642.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(13443..14183)
                     /locus_tag="ACIZE9_001782"
     CDS             complement(13443..14183)
                     /locus_tag="ACIZE9_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HGC6093643.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            14244..15497
                     /locus_tag="ACIZE9_001783"
     CDS             14244..15497
                     /locus_tag="ACIZE9_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HGC6093644.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            15819..16046
                     /locus_tag="ACIZE9_001784"
     CDS             15819..16046
                     /locus_tag="ACIZE9_001784"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HGC6093645.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            16169..16495
                     /locus_tag="ACIZE9_001785"
     CDS             16169..16495
                     /locus_tag="ACIZE9_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HGC6093646.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            16563..17276
                     /locus_tag="ACIZE9_001786"
     CDS             16563..17276
                     /locus_tag="ACIZE9_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HGC6093647.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            17586..18436
                     /gene="licT"
                     /locus_tag="ACIZE9_001787"
                     /pseudo
     CDS             17586..18436
                     /gene="licT"
                     /locus_tag="ACIZE9_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
     gene            18557..20422
                     /locus_tag="ACIZE9_001788"
     CDS             18557..20422
                     /locus_tag="ACIZE9_001788"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGC6093648.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            20436..21879
                     /locus_tag="ACIZE9_001789"
                     /pseudo
     CDS             20436..21879
                     /locus_tag="ACIZE9_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            21987..22688
                     /locus_tag="ACIZE9_001790"
     CDS             21987..22688
                     /locus_tag="ACIZE9_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6093649.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            22814..23326
                     /locus_tag="ACIZE9_001791"
                     /pseudo
     CDS             22814..23326
                     /locus_tag="ACIZE9_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(23724..23933)
                     /locus_tag="ACIZE9_001792"
     CDS             complement(23724..23933)
                     /locus_tag="ACIZE9_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HGC6093650.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            24174..24749
                     /locus_tag="ACIZE9_001793"
     CDS             24174..24749
                     /locus_tag="ACIZE9_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HGC6093651.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            24749..25189
                     /locus_tag="ACIZE9_001794"
     CDS             24749..25189
                     /locus_tag="ACIZE9_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HGC6093652.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            25205..25906
                     /locus_tag="ACIZE9_001795"
     CDS             25205..25906
                     /locus_tag="ACIZE9_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HGC6093653.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(26394..26819)
                     /locus_tag="ACIZE9_001796"
     CDS             complement(26394..26819)
                     /locus_tag="ACIZE9_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093654.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            27193..28164
                     /locus_tag="ACIZE9_001797"
     CDS             27193..28164
                     /locus_tag="ACIZE9_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6093655.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            28196..29593
                     /locus_tag="ACIZE9_001798"
     CDS             28196..29593
                     /locus_tag="ACIZE9_001798"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6093656.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            29752..30375
                     /locus_tag="ACIZE9_001799"
     CDS             29752..30375
                     /locus_tag="ACIZE9_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093657.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
BASE COUNT        10318 a         4932 c         6265 g         8889 t
ORIGIN      
        1 actacctgta ttagtcctct tttttgacca gattttgacc agtctatttt acattctaat
       61 atattcatat gagctaattt tatgattaaa tggtaagtgt ttccttgttt gttttagttt
      121 aaactagtgt gtaatttaaa aatctatatg gaagggtctg tggggtaata cttaaataaa
      181 ggctaggaac ctgataacat caaggttcct agccttttta taataaaatg aagcgaaaat
      241 aatttctttt aaagagccga gattatcagc tatataagag tgaatttgat gcaaaaaaca
      301 gagccgaaac agtcttggtg ttcgtagctc tgcttatatg tttcgaattt aagacaaaga
      361 gttggcaaaa gatgttgata aggaagataa gataactgtg ttatataaac taggtaacta
      421 actgtaacaa gctaatttta agagattctt attagaagac gtttaggaat ataactaaga
      481 aaatgattat acaggtaatt gtcatttcaa taatgttttc taattttcgc gtctttgttt
      541 taagaaaaag gccagaatca gttggaaaaa agttcgtacg atagtgaaga ggggcaaaat
      601 ttcctactaa tattcccact aacaagagat aaaacggcca ggttggtgtg attcctctat
      661 aaaaaaatgc ccatgctacc gaaatcccat agattaacaa ctgaacaatt tttacaatga
      721 aaaaattgtt ctgccattac tcaaagtctc ttcctccttg tatcgtttat ttgtttcatt
      781 ttatcattat gataggcgct tgaacaatcc attttgtatt ttattgagta ctcttggata
      841 aactaccagc gattatcata tttatttatg ttactgtaag ccatcatata aaagtaaatg
      901 agcagatcat agaaatataa aaaagaacta aaattgatct aaattatgtg cagcttgact
      961 acgtaccaat ctatattact tactagattg gtcgttaatc tattcggatc gaatgagcaa
     1021 aatatttttg tgaatgtcca tccttgatta tgattccaaa aagaatcatt gggaggctgt
     1081 ggcgtaaata ttatactata agccagaaat acctatcatt ctgaactttt ttatttagga
     1141 actttcatct caaggctttt tcaattaatt tgtacccctg ttttttggat aagatcatgt
     1201 gcattgattt tttctatctc tacgttcatc tcctacttaa tgcctatctg gctcctgagg
     1261 gcttcttttt aaggcgtcgt catagtcttg gctgaggatt tcttggtaat ctgagggaat
     1321 ggcttcccaa gtgagcaggc gaacgttcat gacgtgtttt cctttgtgtt tgattacagc
     1381 atggtttttc tctttttcta cctctccagc gtgaaaagac agccatgtac catggccaaa
     1441 gatatcatta catacccaac gttcgatgga attgtccacg tatcctacag ggagtgtggt
     1501 atagccgatt tgtggtttca aaaaaggatt gaatcgatcg atcgtttcat ttttgtattg
     1561 ataattgata agaaaaagat agaccaaaca aaagacgagc agaaagaaag atagtgtctt
     1621 tttgagtgag aagggttgtt ttgatgaata agatttcttg ttaacaagag gttcatctgg
     1681 caatgttggt tctattgatt cggtagctga ttcaatagaa ggaaaatcaa tcggcagacc
     1741 taaagtatga tgtaaaagtg acagcatttc aaggtctggc attgtacgag aattttccca
     1801 actagaaatc gttttatcgg aaacaccaat tttttcgcct aattcttttt gcgtaagctt
     1861 acaatttctg cggtaagttc gtattttttc tccggtgttc atcttcttct cctttcgatt
     1921 ctacagtata tagatttatt ctacatgacc tatacacttg atagatacgt ttttttgatg
     1981 aaaaacggta tgattttatc aaagaatcat ttaagtaagg gagagtggtg ataatcaaaa
     2041 aaaagttcac agttttactc acaatcatag tgaccggtat catgagtggt tttgccttgg
     2101 ttagtataaa taaacaggta ctctatcgga caaatgaatt tttccatcaa acagatactt
     2161 atactccgat tcgattgcca caacatttta ttgggcaaga agaatatgag cagctaatca
     2221 tggtatttga aaatgtctca tcagaaactg agctttctta tatgaaaaaa acagtaaatg
     2281 aatccaatga agtagataca tcttggaact tcaagataca gccaaagctt gaaatgacat
     2341 tgtattatca aggggatgtc aaatcttctc acgagaaggt accctattct aatacctcct
     2401 ttcgcgtaac gtccattgaa gaatcgatca aaataaaaga ttttgaaggt gaatttttct
     2461 tgatgacgag agaaaaagaa gcctatgaac ggttcatttc actattcact gatcgattca
     2521 atcaagcatt tcacactgat tatgccacta atatttttga agactttgaa aatagctatt
     2581 cgtattcggt tatttcaaat acagacgtat ataattatcg agtgtattta actattggat
     2641 tgattctttt attccttttg ttatcatcct ttttcttatt gatgaataaa gaaatcagtt
     2701 tattgttgaa taatgacttt tcattacatc aagtattgtg gtgtttattg gggaaaaaga
     2761 aaatcattat tacattcata attgcaggaa tcattggtgg ttttattttt atgtattata
     2821 aggagcaatt tctttatttg ttccagatgt acgttttctt gttcagcgga atatatggta
     2881 tctctttgat ttctctttta ttagttgaaa aaatcgcttc gttaagagaa gcgttcaact
     2941 atatccaata cattcttttt acatttggat tgttgttttc tcttcttttg accgttgcca
     3001 atgtcgaatt agcaactatc gttttttctt cttcacagtt agctgtttcc catgaaccac
     3061 caaaagaaat cgctggtgag gactatcatg tattttatcc agtaaccatc gggaaaaacc
     3121 acgtggattt tatttattcc aatcgttttg catcagcagc agatcaggaa ttatatgaaa
     3181 ctttgaataa aaacggaagt atattagtca atgtatcaga ttacttgaat gaagaaaatg
     3241 aacagtttgg cagagggata aaaataaatc tgaattatct taagaaattt cctttgattg
     3301 atgtctctgg aaggttgatc caaataaccg aaaaagaaac gcaccctgtt atattgatcc
     3361 ctgaacgata tagacataca gatttaaaaa atgacctggc gcaaataaca gaatattatc
     3421 aagaaatcag tgaaaaagaa ccgaaatttc tatttataaa aaacaatcaa cccatttata
     3481 catttattcc ttctatcccc tggatcgaac attatccggt tgttgaaata ctgacattga
     3541 aaaacagtat gtatttggaa agaaatattc tcagcggaga aatctatcca ccgttaaaga
     3601 tcaagatagg ctctttgtcg aaagaaaggt tatttgagct gattgaagaa agtcagttac
     3661 gtgataactt gcagttatca tttccgtata ctcagactga agagatagct gtcaaagtgt
     3721 taagcagatc atttcattac ttgatacaga tatttttact cactttcttt tctttcttct
     3781 tgttgagcta tgtcatgtta tgcatatatt ttgtctacaa ttgtcggaaa atcgctatct
     3841 ttcgttcaag tggttattcg ctctttgaaa cgtataaaga tttcttcatg atgaacctca
     3901 tcaaatgggg aacgacaagt gtaatcttcc tttttcttat agaaagagag cctaaatatc
     3961 tttttaatat ttttttcttt agcttcattg attttattct ttcagttgtt tttattttgt
     4021 ctacagaaaa gaaaagtcag ttattgctga tgaatggagg ttaacaattg gagccgttga
     4081 tagtgataaa aggtgcgaaa aaaatcattc gaaacaaaac gattcttcat ttggatcgtt
     4141 tcactgcgga tgctggggat cttgtgactg ttgttggaga aagtggagca ggtaaaagta
     4201 cgttattgaa tatattagga ttgaatgatc agttcagttc aggacaattc tatttgttcg
     4261 atcaagagac gaaacaatta actgggagag agaagcgctt gataaaaaga aataccatat
     4321 cttttctttt tcaagatttt gggttgattg aatatgaaac aatcgatttt aatttagata
     4381 ttggattgaa gttttcgaat ttaaatgttt cagataagcg aacagcaaag tatgaggcat
     4441 tgaaaaaagt aaatataaac aagaagctaa gtacgcctat ctacacatta tctggtggtg
     4501 agaagcaaag aatcgcctgt gcgagagtct tattgaagaa tagcaaaatc attttagccg
     4561 atgaaccgac tgggtcattg gataaaagaa ataaggataa agtagttgaa atcttatcgc
     4621 aacaagcttc ccaaggtacg ttagttatcg tagtcacgca tgatccatat ctgaccaaaa
     4681 taggaaacaa gaagatcatg ctttaaaaat caaaaaggaa aggatgtcgt tttatgaaaa
     4741 aagcagttat tatttgtgca ctagggatag gttttgttgg aggaaacgct atgtcatctg
     4801 aagtggaagc aaattcagtt cacggtgaaa tctattacaa atctttaaag ccaggagaga
     4861 ttcattttga tgctaaaggt aatattatta agtcaaattt accagtagac cgggaaattt
     4921 ctagaacagc aattaatcat agctctggaa gatgggttta ttatagtgat acaacttgta
     4981 cgagaaaaac aggtcattct aaccactata gtcgtgtcta taatcgtcac ggtgcaaaag
     5041 cgaaagttgg aaactctatt cgatcagcaa atgcaacaaa aggagtatgg gcctatgcaa
     5101 gtgcgacagg aaatagaact gacacattct catgttggta caatccaacc ggttggtatt
     5161 aagtatccaa aagtttatat aaaatagaaa aaacatataa tgaaacagcg ttaaaagtta
     5221 tttttggtag ttttaatata ttcattttta gttgtataaa aatatatcat aataaaaaca
     5281 acaaaaaaat gtctggaaaa tcgaacataa aagtgtctga tttgaatatc ccagcagcgg
     5341 aagaagaaaa acaaaatcga taacatttgt tctaagaatt agttacgtta aatacggaac
     5401 gcaagataga cttgaaaaac ggtaacaaaa gaagtagtat attaaggtgt gatgtgctac
     5461 ttgacattta ttctgctgag cgaactttct ggattgtgta gccttatatc tattcaggac
     5521 gtatcgagca gattagtaaa ggtgttcttg atgattttca tcttgaacac ctttgttttt
     5581 agcaattcgc aaaaaacgaa aagtaggaga attgataaat gaaaaaaaga tttttagcac
     5641 ttgccatcgt actaggcact ggcttattgt caggctgtac gaatgccggt gaaaaaacag
     5701 ccgttagtta taaaggcggt acaatcagcg aacaagaagt aatggatagc ttgaaaaaaa
     5761 tgcaaggagc agattccgct gtgcaacagt tgatcgttta tcaagtattt gaagataaat
     5821 atggagatga cgtatcaacc aaagaaatcg attctcaata tgatcaaaca aagaaacaat
     5881 tgggtgattc atttgattca caattgaaat ctgcaggtta cacagaacaa acattcaaag
     5941 acagtatcaa acaaagtcta gcctttcaag aaggtctaaa gaaacatatc aaattgaccg
     6001 atgaagattt aaaaacggct tgggaatctt tccatccaga agtggaagct caaattatcc
     6061 aagtagcaag tgaagatgat gcaaaagatg tgaagaaagc tgctgataag ggagacgatt
     6121 tctctaaatt agccaaagac aagtcaactg atactacgac aaaagaagat ggcggaaaag
     6181 tgaaatttga ttccactact acaacggttc cggcagaagt caaagaagca gcctttaagt
     6241 tgaaagatgg tcaagtttct gatgtgatca cttctaccaa tgcttcaact tatactacgg
     6301 aatattatgt ggttaaaatg gtgaaaaacc aaaacaaagg caacgacatg gataaataca
     6361 aaaaagaatt gaaagaaatt gcaacagaca caaaattaag tgacagtacc ttccagaata
     6421 aagtaattgg cgaagtattg aaagacgcta atgtaaaaat caaagacaaa gactttgaaa
     6481 atgttttgag tacattcact tcagattcta gtacagcaag tagtaaataa gcggtataaa
     6541 taaaaaatat gaactattta aatcaataaa actgttcatc taaatctttt tattagaact
     6601 aaatcaacag tagtttaatt actacttgat ttagttcttt ttattttaaa aatttttttt
     6661 acttagaatc cagcgaccct agatattttt ctgtataatc ttaaataaag aaaacaatat
     6721 caaaaaatgc acgtagaagt agataaatgg agtggttttg caaatttctt ttatttctag
     6781 aagttattca cgtatacgga tttgtttttc tcacaaataa aaaggcagga agtacaatgg
     6841 atcatttgta tataaaatat attcatcaat tttccgtttt ggtgttaggc acactaatta
     6901 tagcggggat tgtcgcattt attattcaag gccgtgacat attaacagta catcaagagt
     6961 ttttcagtta tgcatttggt attcctctga tcgctataag gtctgataac aaaaagtgga
     7021 agaaacgcta ttacattctc ttgctatttt tgtgttttta tctgccacct aagattttta
     7081 ctttattagg tatacaatgc ctatcatttt cttttatttc ctatatcatt gttttaattt
     7141 tcctcagttt catagtatgg atgttttatc ttgtcaaaaa ataaatgaat gtttcatgaa
     7201 cagtacttca tcacagccta atttttttct ttatgctatc gttatattaa agaaatcaat
     7261 cagaagggaa agaaagtgat gaaaaaagtt ttattagtgg taaaccccag ttcaggcggt
     7321 gaacaagcaa aggaatttga gcaattagcg atagcaaaat tggaatcggt gtttgatgaa
     7381 gtggtcgtct tgcatacaaa aaaagcaggg gatgcaaaaa actttactcg cgaagcggct
     7441 acggaagggt atcatagtgt gtttgtcatg ggcggagatg gaacagtcaa cgaaggaatc
     7501 agtggaatcg ctgaacaaga acatcggcca aatttcggat ttttcccatt gggtacggtg
     7561 aatgacttgg ctcgagcatt agggataccg ctagaacctg aggaagcgat caatcatttt
     7621 tcgattgaat cagtcaagcc attggatatt ggaaaaataa atgacgacta ttttatgaat
     7681 gtcgtcgcaa ttggctctat ccctgaatca atcaatgatg tagatgcgga gaagaagacg
     7741 aaatttggaa aactagctta tttcatgtca ggaatcaaac agttagcttc cacacaatcc
     7801 tactcgtttc acgtagaagt tgatggaaag aaggaagaaa ttgagagcag taccttgctg
     7861 ataggactaa ctaactcagt cggcggtttt gaaacattac ttccaaatgc aaaagtggat
     7921 gatggtaagc tccatttggt ttatttaaaa gattcttctt tgatcgatac gcttaaaaca
     7981 ttgccagacc tattaaaagg agtagatgaa tctacgaaaa atctagccta ccttacttgt
     8041 gagcaattag ttgtgtcatt agctgatgag gaagaattga cgacgaatgt tgatggagat
     8101 gaaggggata aattacctgt gacaatcaaa gtattgccct cacatttaca ggtttattgt
     8161 taaaatggag gttgtgaccg aggagttggc gggagaacac cgcttgttcg ggataaggga
     8221 ctgtgacaag acttttgtca cagccttttt tttgtacaaa aaagaaattt acacctaata
     8281 gaaaaatttt tccataaaaa tacatatttt aaatatgaaa gtacaattgg aaatagatta
     8341 aaacgataaa ataaaattgt caaaacgtca gagaggatgg tggagaatga atcaatgtgt
     8401 aaaaaagctg attgcgtcga ttttgtttgt cttccctctc ttgatggtga catccgtttt
     8461 tgccgatgta gagaaaacaa acgaatcaac gcaatcagag aatcaaagtt ttgacaagac
     8521 tactttttca gaagaatcga ttacttctga aactacagaa tctcaaagtg aggcttctac
     8581 taataaaagg caagaagaaa ataagacaag tgagacctca gaagtagctg aacaaacgtc
     8641 tgatagcagt gaagcggcac tggcaagagc tgtttcagcg gatgggtaca gcgaagctgc
     8701 cacaacagaa gaactggcgc agcttctcgc agacgaatca gtaactaaga tccgactgat
     8761 tcagcctttg actttagaca gggaattaga gatcaaacga gatatcgtta ttgattttgg
     8821 tggattcgct cacaatttcg gcacacacca tatttatatc aatgagatac ctcagtcgat
     8881 cgagttccag aattttaaag gaacagctgc acatccaggt ggattgacac caaatatcga
     8941 tggaaatgcc attatcattg cttatatgac cgatttttgg ggaagcagat atcattttac
     9001 gggagaaata aaatttaccg ggacacttga tttgtatgat gggtccaaat taggactgat
     9061 ttacgctcct cgtgcaactg tcacattaga tggtgtttcc ggtgtgttgg atgtccaacc
     9121 agtgaaggaa ggactgaatg ccgctccggg taaagcctat ttttgtagaa gctatcaatt
     9181 gaatgtgatc aatggtagtc aactttatgg accgtatcta gggaaattct acggttttct
     9241 agattcagga gatgagactg gtagtggaaa aacagcgcca ggaatccata tcttaagcgg
     9301 ttcaaaggtc tctcttgatt atgatcgggc agatggcgtt agcgatgaag gagaggcagt
     9361 cgatacgcta cctggtaatg tcatgtttga agtcagtggt tcgggaagcg aattttcggt
     9421 aaatacaaag atcaatatta ccaatgacaa caatcgcgga atcatccaaa tgagaggttc
     9481 aggatcgaaa gtcactgtat cgaatggtgg gaaaatcacc atcaatacag caactacggg
     9541 cggatttcgc ttgcaaggag attctagtca aatccatgta tcaagtggtg gacaaatctc
     9601 ggtcaaaatg gctggagatg acgatcaacc cgggaacaat gggatgcgtt ttgtaggaaa
     9661 aggcctttct ttgatcgtag aaggagccgg atcagttatc gacatcgata agcagagtgg
     9721 gcgttccagc gcagttcgtt ttgagaatgg tacgcaaaag ctgacagtaa ccaatggagg
     9781 ctcattgagg gtaagaaata caggtgatgg caaatcttac gtgaacagac tcaatcaagg
     9841 aaatcaagcg atccaatttt atgacgcttc tggttttcta gaaagtccag gttcagctga
     9901 ttttacagtc actggagaaa aatcaaatat cgatatacgc gcagattccg gagcaactgt
     9961 agatacaact ggagatattg atttaaattt tacggcaggt gaaaaaactt atttagtcat
    10021 ggtcgggaaa acaggggaag ataagaccgg catcatcagt ggggatgtgt tgaatgtgga
    10081 cttagaatct cctacctatt ttgatttcca aaacaaacgg attggaagcg agaccaatgg
    10141 cataggcggc tgggtattcc aaggaaatgg agattcttct ttaaagatcg cccattcaga
    10201 aatcgcttta tggcgaaaaa caggcgcaac attcgataac tttgaaaaag acccggatta
    10261 tttttctgat atgacagact tatcgatcaa tgggaccgac ttaggcaatt tcgtatcaag
    10321 ccctagtgca ggtttaacaa atgaatttgc tcagacaggt gccggaatga aaaattataa
    10381 tcgaatcagt gccaataatc agctcccgat gattgaatcc ttaagagtgc caacgaatgc
    10441 agataaaaaa atctatgggc atgtcgttgt tcccgaaggt gtcgaggcaa agccaagaga
    10501 tgcttggaca ggcgaagtag aagtgacttt acgtattact tacgcagata cgacgaaatc
    10561 atctgtagaa attactgctc tcacgcaagg acaaacagat gaaaatgaag gggcaggata
    10621 taacccatgg ggagaaggcg aacaaggcgg cttgttcgaa gttcaagtac ccaatgatga
    10681 gagattaaaa acggaggatc aagtgcaagt tgttgctgct aaaaaagtaa gaggtggcca
    10741 agaagtgaca gaactggact ctgccaaaac gacagtcgat gtgattcctc ctgaacctgc
    10801 taatttaagt accacattga tcaatgcagc ttctcgcacg atcacaggta caggtgaagc
    10861 aggagccttg gtttcattga aaaaaaatca agctgttttg tcagaaacaa ctattgatga
    10921 tacaggggaa tttgttcttt ctatcccaga aaatcaactt tttgcaggag atgtattaga
    10981 aattgtatta aacgaccaag caggagaagc tactgctaag ggtgtgcaga acaagccaag
    11041 taccaacgat gaaattggga atcacaatcc aagtgatacg ccagttgttt atcatgatgc
    11101 cccgcctttt gcacctgcta cgaagatcgt agtagaaggt ggtctctcat ttcttgcccc
    11161 ttccaaactc gattttggtc agatcaaagc aactggtttg acacaagaag catttggcca
    11221 aatggatata caggaaaaat tatggattta tgatcagcga gaaacgaaaa atccgtggat
    11281 cttaacgata aaattatctc agcctttcac aaatgatgca ggattttcta tgcaggatgt
    11341 cctatatttc aagaaaggag aggagtatca attagtgaat gaagaagaac tggaaattgt
    11401 cagaggacaa aattcaacga atgtgcaagc agattattca gaatatttaa ataacggtcg
    11461 ggcgtttaaa cttgtcttaa ccaaagaaaa tcagatagct ggtaattact cagcagagat
    11521 aacatggaca ttagcagatg cgccgacaga ataaagatca aggaggatga ttgatgaatc
    11581 gaatatggaa taaaagtcat cgaaacaact gctctttact tatgatcctt ctccttggat
    11641 tcatcctttg gcagacacct gtccatgcct ccgaattcaa ttttgcggta gattttgaat
    11701 taccggctaa tcagattgat aagaacaaaa catatataaa tgtaaggatg gagcctggga
    11761 aaacacagga aatcccctac acggtcttta accgaacaga taaatcagta acagttgaga
    11821 cattgatcca ctccgctacg acgaattcaa acggtgtgat cgaatatgga gaatcaaaaa
    11881 gtaaatttga tgaaacatta agttatgata tgaaaaactt agcaaaaaca gtgggagaaa
    11941 taactgttcc tcctcaaagt gcggtcactg agacactttc actgaaagcg ccagaaaaag
    12001 agctggctgg tgtggtcgca ggagggatca cgtttcaaga aaaaaaagag aacgtttcta
    12061 acaaaagtac agttggtgtc gtcaatcagt tttctcaagt gaaagcaatc ttgatttgaa
    12121 atagcgaaaa agagtcttcc ccagatttga aattaaaaaa agcttatgcg gatcaaagcg
    12181 atggaagaaa tgtgattaag gcgaatcttc aaaatccaaa tgcttcttat atgttcggct
    12241 tgactacatc ggttgaaatc tacaaaaaag aaacaaaaga gccttacctt tcaataaaaa
    12301 aagaaaaaat agatgtagca cccaatacaa attttgattt acttgtccca ttagaaggaa
    12361 aaaaattagc tccgggacat tatcaagcgg ttgtgaaggg tgcttggaaa gaaaaacgct
    12421 ggaatctcca taccgatttt gaaataactg atgatgcagc ggaccaattg aatgaaaagg
    12481 atattgattt aaaaaatcag ccagaaacat ttgactggcg atggctgata cttgttggag
    12541 tcattcttat tggcttattt gctggattat ttattttaaa agaaagaagg aaaaagaaat
    12601 gaaaaaaaca attgcattaa gtaccgttct agctggaagt ctattattat gtacacaaag
    12661 tgtttttgct gagaataaga gctcagccac tacagaagga acgatttctg tgaccaaacc
    12721 agatgctgca aatcctgaag acgttgttcc agttcctcct gttgatccaa atgatcctga
    12781 tactcctttt acacctgacg aaccaaatca gggaacatcc ggattactga cgattgacca
    12841 agctccagat cttgattttg gaacaatcaa gttaggtaca gcaaaaacag tatatgctgc
    12901 attacaaagc ggaacggaca gtactggagc acaaacacaa gtacagaatt tcgtacaagt
    12961 aacggataaa agcggaaatt atgccggttg gaaattatca gtcaaacgaa cagaatttat
    13021 tggtacaaca tctgatacga ataaactaac tggttcaaag gtgaaattca aaaacgccgt
    13081 gattcgaaat agcgcaacta atagcagtgg aatgccatct accgtttctg gaactggcgc
    13141 tgaaggaatc gaaatcccag cagatcaggc agtagatcta gtaactgcag gagcaaatga
    13201 agggattggc acatggattt attcattagg agagaatgtg gaacaaggga gacaatcagt
    13261 ggaattattt gttcctgtat ccaattatgc tgtagacaac tacgtttcaa cattcacatg
    13321 gtcgttaaca gatgctccta cagaagagga agcgtaaaat catatcaacg atttcaggga
    13381 gtggagccga ttcaaggccc actccctgaa atctgctatg cttacgtctc agctcttatt
    13441 catcaactcg aagcagtttt ttggaagtca tggaaacgtt cctttgtctt ttcaaagatc
    13501 tttcgaccaa cgagtaagga gtcaccgttg aaaaattcta acacataatg agcagaatca
    13561 attttctgca attgcgataa gttgatacag taagatttta aaagtaaaaa gtaagcatac
    13621 ttttctaact ctgtcttcaa ttgttttaaa gaagtattca ctaatttatc ttctgtagtt
    13681 gttttgacca taacttggtt tttcaaacct ttgatacttt caatatataa aatttcccga
    13741 ggatacagga cgagacttcc acctttttga tcaataaaga ttttatcgac atttacgatc
    13801 tgctgttctt tccaattgat ctgttctagc acttgacgaa tttgttcaga taaattcctg
    13861 tcttttctga tatatccaat cggaaggatt ttccgattga tgatctctac tgcaaaattc
    13921 gtataagcgg tgaaaaaaac aatattacta tgtgcatttt ttttacgtat ttgttcggcg
    13981 acatcaatac ctgtgagtga ttgcttcaag tcgatatcga taaagaaaac atcgtgatta
    14041 tcaatagtgc ccaactggat caactgattg atttgagaga tagaagtgag ctgcacgata
    14101 ttctcgatat gatgattgac caattctctg atgatccatt cgctgtgaaa ctggttatct
    14161 tctatgataa aatacttttt catatgcagg ctcctattaa aaaaatatgt gtacattttg
    14221 aaacaaaaca atggaggaat aagatggtcg caacagtgac actttatttg acctttactt
    14281 tgattttaga tttaggtatc tatttattct tttcgaaaca actgctagta aaaaacagct
    14341 ttggttgtat agctttgatg gtggtgacac ttttacttcc tatccctaaa gtgagctttc
    14401 cttacctagt tggcttatta ttgatgtttc ttttttattt tactacgaaa aacctgttta
    14461 tcagctgttt gatcagtaat cttttttttg ctatcactgg actcagcttt tttctggttt
    14521 ttgatctgat ggattattta ggaaagagac atcttggaac agcaagtttt tttgcactac
    14581 ttatcgcatt tattttctat ctattagtaa aaagtataga caaacagacg agatttctca
    14641 acttgctttt tacttatcca actgaacact attttggagg tatttgtatt ttattaagct
    14701 ggggcgtgat ttacttggta ttgggaagtg ttcacttccg ctcatctaat tatctgcttc
    14761 tatctctttt gtcgatagtc atcagttttt tttctttgtt tttttccatt atgttgatca
    14821 gtttccaagt aaaagaaaga caacatcagg aatcgcttca actgtatcaa ataaatgaag
    14881 aatattacca tcatctagag gaattcaaac atgattataa aagtctactg ttttcattaa
    14941 aaattactct tcaggaaaat aaaaaagaaa cgttggaatt tttagaaata ttagaagatc
    15001 attctgcagc tatttttgaa aaaccgcaaa tacaacagct aacaaatatt gtatccccag
    15061 ctgtcagggg tgtcttttta aaatttctag aaaaagcaga atcggagaaa atcccgatcc
    15121 aagtagttat tcctgtcgaa gtgaaaacaa tcccgattga tctggttgtt tttattcgct
    15181 gtttatctat ttttatttct aacgcattcg atcatcgtgt agccgatcag agtccgatta
    15241 cgatcaatct gctggaagaa aaagagggat cacgttttag tatagcgaac aaggcaaatc
    15301 caacgaattt gacgctatcg gagatggtca aaagaggaaa aacctctaaa aaaaatggcg
    15361 ggttaggtct atacagtgcg aaaaaaatgt tggatgttta cgaaaatgca gaactaaaaa
    15421 tcgaattttc aaaacagaat cactattttt ttgtagaaat gtatctggca tctagaaaga
    15481 gcaaatcagc ctactgactt actgtcaaag gataagtttg aggaaagtct acacggagat
    15541 agagacaaca acacagcata ttcaaaagaa acagaagcgt gatgaccgtt gtcacccttc
    15601 tgtttctttt gctatgtagt taaacaaagt agttgacact tccgctactt agtattagta
    15661 cgaaagtata cttcatgata ctaagtagat aagaagtgaa aagcggaacc cacgatcgtc
    15721 aaaatgctaa ctgctttgct tacaccagat aaagggaaga gcaatatcgc ttattttagg
    15781 cgtggagaag caagcaaatc cctacgatca caaaaaaaat gctgacccag cagttaagag
    15841 agttagaaca agatgaaagt atccatcgaa aagcctataa ccaagtcccg cctaaagtag
    15901 agtactcgct caccgaagaa ggaaaatcat taagagagat tctagtagcg ttgtctgttt
    15961 gggaagaaga acgtatcgaa aaacaaaaag cctcaaggga agaagacacg ctactgcata
    16021 cacatggtgg ctacctaaat tattgatttt ctatgacatt tattttaaat aaaagaaaac
    16081 aggagttttt ttaaaagcat catctatttt ttatgtaaaa aaatggtatg attaatcaag
    16141 taagaagtga ttggaagaag gcaagcaaat gaatagtatg gaaaaagtca accagtttag
    16201 agatgaacgt aattggcgac aatttcataa cgaaaaagat ttggctatct ctatttcttt
    16261 ggaagcatct gaattgttag aactttttca atggaaaacg ccggaagaag taaaagaaac
    16321 acaattagaa cgaatcaaag aagaactggc agatgtattg atctattcat acatgatggc
    16381 agacaacctt cacctggatc tagatgagat cattgaagaa aaattgatca aaaataattt
    16441 gaaatatcct gtagaaaaaa gcgcaggtgt acgaaaaaaa tacacagagt tgtagaaatg
    16501 tgtcattcgg ctgttggaaa gagcaaaaga aaaacagtaa aatgagtctg gagggagaga
    16561 aaatgaaaaa aaaaggaaaa gcaaaaagat ggctagtcaa tatcctcttg ttcctcttgt
    16621 tattagtagg actagctttg attttcaatg aacagatcaa ggattatttt gtcagagaga
    16681 caggagataa atatgctata gcgaatgtaa caaaagaaga tctgaaaaag aataacgata
    16741 aagatgtcag ttttgacttt gatgcggtag aaccaatgac gacagaaggg gtcatgaggt
    16801 cgcaaatgag aggaacagat ctaccagtga ttgctagtat cgcagtccct tcagtttcaa
    16861 tcaatttacc ggttttcaaa ggcttggata atacgtcact actttacgga gcaggaacat
    16921 tatctccaga tcaagaaatg ggaaaaggaa attatgcctt agcaagccat cgtgcaacga
    16981 accctgaatt gctgtttaca ccgctagaaa atttagagat gggtgccaag atctatttga
    17041 cagatttaga aaatgtgtat acatacaaaa cattttttaa agaaaaagtt gctcctacag
    17101 atacccaatt actgaatgaa gtcgagggaa aagaaattgt cacactaatt acttgtggcg
    17161 acatggacgc cgtcacgcga ctagttgtac aaggagaact ggaaagtgtt acatcgataa
    17221 aagatgcgac agatgatatg agatctgctt tcaatctaga gacaaaaaca ttttaggata
    17281 ctgggacata agtcgttaca gattaaaaac agccaaagga tatgaatcga taaggaaaaa
    17341 ccaatttgct gaaaaaaaga gaaacgcaaa gaggtgcatc tctgatttgg ttgttttcta
    17401 gatagacttg tgttccagtt tttttatttt ttatatgaaa aggcttgcat aaataaaaat
    17461 tcgatggtat gatgattttg aataagaaat ggattgttac tgtacggcag gcaaaaccag
    17521 aattcagcta agaaacagta ggcgaattct aggttttttt atttttcttg agagggcgaa
    17581 gcaaaatgaa aattgataaa attttgaata acaatgtcgt catttcgaaa aatggattcg
    17641 gggaagaagt cgtttgtatg ggaaaaggac tagcttttca aaaaaagatt ggggacgaga
    17701 tttcgccaga agcggtccaa aaagaatttg tttaagagat tcttttgcta aaaaccaatt
    17761 ccagcagctg atggctgata ttccggcaga ggagatcgaa tgggtcaaac aagtagtcga
    17821 actggctgaa gataaactaa aagttgaatt ttcgcctaat atttatctga cattgaccga
    17881 tcatcttcat tatgcgatca cacgagcaaa agaaaatatc caactgccta atccattatt
    17941 atttgaaaca aaaaaatttt atccgaaaga atatcaagca gcgaaagagg ctcttttgtt
    18001 cgtgaaacaa aagacgggtg tggaactttc tgaggatgaa gccggtttta ttgcctttca
    18061 ttttgtgaat agccaacaag gaaacgaaga catgcaagtg acgatgaccg ctaccacaat
    18121 ggtaagagat atactgagta tcatcagtaa attcttcggc atcgtgttcg atgaagaatc
    18181 tttgaattat cagcgtatca ttactcatct gcagtttttt gcccagcgtt atctcaaagg
    18241 ggaaggatct gacgagcaag atgaatttct ctacgcatta gttcaaggaa agtatccaaa
    18301 agcgtttcat tgtgtcgaac ggatcaatga gtatcttcga caaacgcaaa aacaggaaat
    18361 ggggatcgca gagcagattt atttaacgat tcatattcaa agagtagtaa gtgagaaaaa
    18421 aagcatccaa tcataaggat tgttactgta tggcaggcaa aacctggatt gaaaaaatag
    18481 gttcacgaat gtttgtgact gtttttttca atctgggttt ttatttttta aataaaaaag
    18541 aaagaaggaa aaaacaatgg ataatcaagc agttggtcgt cgtgtatggg aagcggtagg
    18601 aggacaaaag aatgtcaaaa gtttagtaca ttgtgctacg cggttgcgat tcagattaaa
    18661 agatgaatct ttagcagata cgcaaaagtt aaaagaagac ccggacgtga tccaagtcgt
    18721 acaaagtggc ggtcagtatc aagtagtgat tggcagtaat gtagcagatg tttatcaatc
    18781 gatcgtggat gaggaaggtc ttgcagtttc ggaggatgga aaagaagagt ccaaaaatat
    18841 tttgaatcgt ctgatcgata ttatctctag tatatttaca ccttttctag gggcgatggc
    18901 agccgccggg gtattgaaag gattcttatc attggcaacg gtgatgggct ggctgacagc
    18961 tgatagcggt acttatcaaa tattgtttgc tgcagcagat ggtgtcttta ccttcttacc
    19021 tgtcatgctt gcttttacag cagctaaaaa gttcaaagcc aaccagtttt tagcagtagc
    19081 aattgctatg gcacttgtgt atccagctat cacagcagtt gctggtgcgg gagaagctat
    19141 cagtttcttt gggatcccag tgattctttc accatctggt tatacttctt ctgtcatacc
    19201 aatcattcta gccgtatggg ttcaaagtaa attagagcca ttcgtaaaaa aagtgattcc
    19261 gcaatttctg caaatgattt tagttccgct tgtcgtttta gtagtgatgg ttccattaac
    19321 atttcttgct ttaggaccaa tcgggacggt tgccggtaat gctttaggcg gtctcttcaa
    19381 ctcgatttat ggatttagtc caatcgtagc aggtctaatc atgggaagtt tatggcaagt
    19441 attcgtgatg ttcggcatgc attggggatt cgtaccgatc atgtttttga atatcgaaca
    19501 atatgggttt gatgtattga tgccaatgct tcttccagcc atcttggcac aaggtggggc
    19561 tgctttagct gtagcattgc gaacaaaaga tacgaaactt cgagcattag ggatttcttc
    19621 tacagtgact tcgttatttg gaatcactga accaactgtg tatggtgtga cattaccttt
    19681 gaagaaacca ttcattgccg cttgtatttc tggaggtatt ggtggagcta ttatcggatt
    19741 ttccggagta aaagctttct ccagcagttt ggtcagctta ttgacgattc cgactttcat
    19801 taatacggtg gatggtgtag agtcaaatgt gacagtagca gtaatagcta caggaattgc
    19861 ttttgttctt gcattcgtag gtacattgat tttaggattt gacgaacaaa cacaagacaa
    19921 tcaattagaa aacaaacatg cgaatgcagg agaaccgatt acttcagcac ggcatacctt
    19981 aaaaagtcct ttaacgggta aagtactgcc attgagtgaa gtaccagacc aagttttttc
    20041 ttctggcgtg atgggaaaag gtatcgctat tgatccagaa gtaggagaac tagttgcacc
    20101 tgcagacgga gagatcacga ctatttttcc aactggacat gctgtaggga tcacaacgac
    20161 tgacggagcg gagattttga ttcatatcgg gatggataca gtagaattaa atgggaatgg
    20221 ctttgagatc ttagtcaaac aaggggatct cgtcaaagca ggagatttat tgattcgttt
    20281 tgacatcgaa gcaattagag cagctggcta tagcgtaatc actccagttg tcattacgaa
    20341 tactgatgca tttgccgata tacttgaatt agaccaaaaa gagattattg caaacgaaga
    20401 tgttctggca attgtaaaat aaggaggaaa tcaggatgca atcacgtttt tcagaaaaat
    20461 ttttatgggg tggagcaact gctgccaaat caattagaag gggcttatga tcgagacgga
    20521 aaaggactat ccgttgcaga tgctatgcct ggaggtaagc agcgctttgc gattatcggc
    20581 agtgaagaat ttgactggac gattgatcaa gaaaaatata tttacccgaa tcatcgagga
    20641 atcgatcatt acgatcgttt caaagaagat cttgccttgt ttgcggaaat gggattcaaa
    20701 tgttatcgtt tttcgattgc ctggacacga atttttccaa atggagacga aggtactcct
    20761 aacgaagcgg gattagaatt ttatgatcag ctgattgatg agtgcttaaa atatgatatt
    20821 gaacctgtga tcacgatttc tcattacgaa atgcctcttc atttggcaaa agaatacggt
    20881 ggctggaaaa atcgaaaact gatcgacttc tatgaacgat ttgctcagac agtattagag
    20941 agatacagca gtaaagtcaa atattggatg actttcaatg aaatcaattc ggcctttcac
    21001 tttccagctt taagtcaagg attagtaaaa agcaatggag caggagagta ccaaaatatt
    21061 ttccaagcat ggcataatca attcgttgca agtagcaaag ccgtaaaaat cggccacgaa
    21121 ttgcgttcgg atatccaaat cggctgcatg attatctatg caacaactta cagcatcgat
    21181 gccaatccag tcaatcaggc agcaacaatg atccaaaacc aagaattcaa ttttttctgc
    21241 acggatgtcc aagtacgtgg agaataccct gcatacacag cgcgtaccca taaaaaatat
    21301 ggagtcgatc cggaaaaatt agagcaaacg gaaaaagact tccagttgct aaaagaatat
    21361 ccagtggact acatcggatt tagttattat atgtctacgg caatcaatga gactgatcca
    21421 caagcagcaa cttcagaagg gaacttgctg ggaggagtaa aaaatccgtt tcttgaggca
    21481 agtgaatggg gctggcagat cgatccagaa gggctgagaa tcgcattgaa tgaattatac
    21541 aatcgttacc agaaaccatt attcattgtt gaaaacggtc ttggagccat tgatcatatg
    21601 gaagaggatg gcacgattat tgatgattat cggatcgatt atttacgtcg tcatatcgaa
    21661 gcgatggcta atgcagtagc agacggtgta gatttgatgg gctatacgcc ttggggatgt
    21721 atcgatcttg tcagtgcatc aacaggagaa atgagtaaac gttacggctt tatctatgtg
    21781 gatctagacg atgaaggaaa tgggacactg aatcgatcaa agaaaaaatc ttttgattgg
    21841 tataaagaag taattgcctc aaatggcgta aacttgtaat taaagcagct gaatgaaaaa
    21901 gaacacactt ctcacatgtg atttgtgttc tttttttatt ttttatgtgc tattctttta
    21961 gtaatagtaa agcaaagggt gacgttatga aaaggacacg tgtactatac ttggaagtcg
    22021 cagataaaat taaagaagat attttctcag gaaaatatcc agtcggttcg atgttgccga
    22081 cagaaagtga attagaagaa ctgtttcaag tcagcaaaat cactgtccga aaggcaatcg
    22141 aactgctggc atcagatgaa tatgtcgcaa agaaaagtgg tcgtgggacg acggttctaa
    22201 gcaatcgtcc ttacaatcga ttatccaaag cggcaagctt tacgcaaatc ttggagaact
    22261 cccgatatga agtccggaaa gaaacgctgg atttgcaatt ggtccatata aagaaggaag
    22321 atcctttgtt ttcctttttc ggtgagcaag ctgtttgttt taagcgctta tattatttga
    22381 acaatcagcc ttatatttat tttgttcatt atcttccaca agaaatgatg caattcagca
    22441 gagaagaatt tggcaaagaa tctttgtatc gtttgctgac gaaaaaagga tatactattg
    22501 actcattttc tgatgatttc tcggcagtat ttttaacaga agaagaacaa ggaattctga
    22561 aaacagacgc acagatcggc atcaaacgga tacggaaatc gtctacgcaa attggggaaa
    22621 tgattgaata ttcggaggcg gtctaccata cggagctgca tccttaccat attgattatg
    22681 aaacataaat aaaaaaagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
    22741 caaacaaaaa tagcttctca tatttttcgt ttggttaggc ttattaccgc agatacacgg
    22801 ctgtttctgg attaccattt attctggata agggggtgtg gcacgatttt cagaaggaat
    22861 ctatgaacca atcactgtat tgattttagc ttcgatggta accccattcg gcttgacgat
    22921 cgcttatttc ttagggaaaa tcattcgtaa aaatatactc aatcgtcaag aaatcgatac
    22981 attgaagacc gcttttccta tggggatctg tcagatcaca gagggatgtt tccctatcgt
    23041 attgaacgac ttggcacgca atgtcatagc aacgggagtc ggtgggacag taggtggcgg
    23101 attaagcatg ttttggggcg cagatagccg tattccggca tcgggaatgt ttgcagtcgc
    23161 tacgatgacc agaccatggg cattcattgg tgcattgtta gctggttctt ttgtcacagg
    23221 aataaccatt ttattattga aaaaaccagt agatccgaat gcagaaatca tccaagaaga
    23281 aaaagaggaa gaagacatat cttgggatga tttgacaatt agttaggaga ggcagaatgg
    23341 attacaagaa aaaagtacaa tagatgtacc ttgagacagg aatggtatga aagaatcaga
    23401 gttagaaaga atcgaatata cagattttgg tttaggagcg atcgaaactg tccagagcat
    23461 cggcaccctc cttgaaatga cgatgaagga aaaatgagaa cctttcgttg tcgaaagggt
    23521 ctggtatacc ttatgtcgaa ggaaaggaaa caaaaaaact ttcctgtact attccaaaaa
    23581 ggaaagaaag ttattataca gtaaaaaaag aaattattct tcatgctaga gatcagtaca
    23641 cgttcgagcc caatatcaaa cactagttcc aggcaggcgc aacaggtgcg gttatcactg
    23701 aattttcttc cagcagtgac gattcaagtg atatttttac aaatccagct atttatcgtt
    23761 aacaaaaaga tttttaggag aagctgatga acaaaaatga tcaaattttg atcgtttagt
    23821 tcgtcggctt ttttatttag agaaacatca tttatcagtg aaacataaca cgagaacaaa
    23881 atgatttttt cgttaataaa agaaacaagt atttgttgtt taaaataata cacgttattg
    23941 gcatatagga cgaaatccca gtatcttcta taagtaagtc atttcatatc gatgaaaaca
    24001 cgttatttat ttttgtttta tctataaaat ggctgaaaaa tgattttttt ctaaatacta
    24061 tatatagtgg cgtctatcct atataccact aaaaaactac aaaatctagt cttttatttt
    24121 aaaaaaacac gtgtagaatg aagatagact tttgagttag ggagtgtttt tttatgaaac
    24181 ttactgtttt ttgcggttcc cgttttggta ataaagaaag ttacaaattt attgcgcaaa
    24241 cgttaggaaa atacatggca caagaagaaa tcgaactggt ttacggtggt tcatactccg
    24301 ggattatggg agtgattagt aaaacagtac tggaaaataa cggaaaagtc acaggtatct
    24361 atccgaatgg gctttttgaa actgaattgc ctggaaaaga tgttactaca tttattccta
    24421 cagaaacgat cgatgaaaga aaggtattat tatttgaaaa gggagatgct gtcctcgttt
    24481 tccctggagg tctaggtaca ttggaggaat tctcacaact tctttcttgg atagcaatcg
    24541 gtctgacgcc cgacaagcca atcggaatat tgaatattgg cggttattac agcggcttgc
    24601 aacaattatt agaaactttt gcaaaagagg attttatgga taaaaaatgg ttggatcaag
    24661 taatcttttc caacaatcca ttggaactgg tcaatgaatt acgagcagta tctattaaaa
    24721 atcagttatt attgaaggag gcaaaataat gagtcaaata tatttagcag gaccattttt
    24781 ttcagaggag caaatcgatc gagtaagtcg tatcgaaaaa gcgttggagg aaaacaaaac
    24841 agtcacaagt ttctactctc cacgtcatca ccaagaaagc aattatgaac tattcagcgc
    24901 tggatgggcg caggaagtat acgaaaaaga tatggaagaa ctgacaaatg cagaatttgt
    24961 tgttgctatc cttgactttg agcatcaaac aatcgatcca ggaacggctt acgaattagg
    25021 tgtggcaact atgttgaaaa aaccgatgat cattgtacaa gaagagacgg tacctacgaa
    25081 cttgatgatt acacaaagtc tccatacgta tttaaaatca gaccaagctg tacgtgaata
    25141 tgattttgaa acattgcctg ttgaaactta cgtaggcgag tacttataga agaggaaggg
    25201 ttgtatgtca gtgattttga tttcaggaac gattggtgca ggtaagagca gtttgacgga
    25261 tatgcttgca aaagagattg attctaaacc attttatgaa aatgtcgaag ataacgaagt
    25321 attgccgctc ttttattcaa atcctgagca gtacgctttt ttattgcaaa tcttcttttt
    25381 gaacaagcga tttttagcaa tgaaaaatgc tttagtgaac gatgacaatg tgctagaccg
    25441 atccatctat gaagatagcc tgttgttcca tctaaacgct gatttaggtc gggtaacgga
    25501 tatcgaagta cagcagtacg atagcttatt agatacgatg ctaaacgagt tagatgatgt
    25561 tgctccaaaa aaacggcctg atttgatggt ccatatcaaa gtttctttgg acacgatgct
    25621 agaacgtatc aaaaaacgtg ggcgtgacta tgaacagcta gaaagcgatg agacgttata
    25681 tacctattat gaaacgttga acacccgcta taatcaatgg tatgaagatt ttgatgtatg
    25741 tcctaaaata caagtggatg gggataaatt cgattttgta gaaaatccag aagatgcaaa
    25801 aaaggtgatc cgtcagatcc aagaaaaatt agctgaattg gaaggaaagc ctgctggaaa
    25861 atattttacg gataaccagc atgcaaaagg tcaagaatta ggctaaaaat aaaaaaccaa
    25921 acgacgggaa agaaaaatta ctacgtgatg tagaataagc ctttctatcg tttggttatt
    25981 ttatattcaa atatttgaaa taaataaatc tttactcttt gatttgtaaa ctgaaatgat
    26041 ccactgtttg ttttactgat gaagcttgat caaaggaaga agctgagttt gaagttcata
    26101 aaaatcagcc atagtgagtt ttgcttggat ttgtttatct tcttctactt tttacataat
    26161 tttgaacagg ataagattca aatgttttaa atgaatcttt gactagtttg tgacagttgt
    26221 cgcatatgct caagcttcct tggtcattaa attctgtatg gatatttttg ttgttattac
    26281 atgtacaata atcaggacta tcgatcatcc atttcgtctc ctttacaatc atcttgcttc
    26341 tttactatag cagaaaagaa ggggagaaac aaaagaagat ccaacagacg gcactataga
    26401 ctgtagatgt tgccatcctc atccttcaaa cggtaattac cgatttttgt aaatatgact
    26461 gttgtttctt ttttattttc ttttcctgaa ataatatatt cgtcatcttt ggtagtgatc
    26521 ttgatatctg tcagcactgt tttttcttca gatgattcag aagaatcagt tccttgtgtc
    26581 tgatacgtgc gtgtccattc cattttttta tctgtaaatg tcaactgtcc cgcggataaa
    26641 tccatatctt tacgtacttt tagcgtatat acactgttgg tggtatctgc tttttccgct
    26701 tttaagacag aagaatcggt tgtttcgtcc gaggattggt cagagccgcc aaacaaatca
    26761 cagccagtca atgtcaaaag tcccgcagac aaaataaata gtacgattaa tttcttcaaa
    26821 atacttcccc catttgatag gataaagaaa ttataccatt ggaatgtaaa acttcaaacg
    26881 gatggaagag aaaaacgcac aaaacaccca caaatagagt aaattttaga ataaaatttt
    26941 aaaaaggcaa aaaatccgcc actttcagaa agcgttttaa aaaagtgttg caatctttta
    27001 aaaaaatgct atattaaaaa tgaaccggtt caaatacttg tttaagtata attaatagtg
    27061 agaggaagtt gctctactga agactttagt tatatggata ttgatgacaa gcaacactat
    27121 gcaaagaatg cggtcatcat aatcgaacaa caagaaagag aaatcaaatg taactggcag
    27181 gagtgagaat gtatggcatc gatccgtgat gtggctaaga tggctggtgt ttcagtggga
    27241 acagtttccc gttacttgaa tggtcagcaa ctgaaggaaa agaacatgaa aaaaatagca
    27301 gaagcgattt cagcgttgga ctataaagaa aacatcattg ctaaagggtt gaagaataat
    27361 cgaagcttct ctattggact tttgataaac gggatttcca gccgttttgg gtcggaagtt
    27421 gtctcaggga tcgaaagagt agctgaagaa aatgggtata gcttattatt aagcgggttt
    27481 gccgatcagc cagaaaaaat tgaacaaaaa attgaatacc tgatgaagca tgtgatcgat
    27541 gggctgattg tcttcttatc cgaagaagag tggtctggat ttgaaatgct cacaaaaatg
    27601 agtattccag ttatcgcatt gaattgtcca gaaggaccag caggtattga tacaatatta
    27661 gtgaatgatc gagaaagtgt agcaaaagtg atcgctcatc atggtgaaca aggacataaa
    27721 aaaatcggat ttattgctgc cactcaaaca gactacgtag caagagaacg tttagcagga
    27781 gccaaagaag cggtccaaaa tgatccatcg atccaattag aggtctttac aggagactat
    27841 tctagaaaaa gcggctatta cggggcaaaa gcattattag aaaaaggggc aactgctatt
    27901 tttgtcagca attacaatat gtcgattggt gccatcgaat gtttcaatca agaaggtgtc
    27961 agaatcggga aggatattgc gttcagtcac tatgattatt tagataaaaa cgatctgagt
    28021 atccttccga aaatcacgat cacgccacca acagataaaa tcggggaacg agcagcagaa
    28081 cagctgttaa aacgaatcaa aaaagaagag gaagaaaatg aaaaagtgat tgtgatggaa
    28141 aatatcatac atggaatcaa ctaaaacgaa ctaaaaaaga aaaagaggtg ctttgatgaa
    28201 aaaatatcaa tttccagcaa atttttggtg gggttctgca gcaagtggcc cacaaacaga
    28261 aggaaggatt tcaggcgatg gaaaaggaga gaacattttt gattattggt acaaaaaaga
    28321 accgcaaaag ttctttgatc aagtaggacc tgaaaaaacc tcgcaagttt atacgaagta
    28381 tcaagaggat gtacagttga tgaaacagac tgggcataat tcatttcgaa catctatcca
    28441 atggagccgt ttgatacctg atgaatctgg aacaatcaac gaagaagccg ttcgtttcta
    28501 tcatcgttat tttgatgagt tgattgaaaa cggtatcgaa ccctttgtga atctgtatca
    28561 tttcgatatg ccgatgtatc tgcaagaaaa aggcggatgg ttgaaccgag aaacggttga
    28621 agcctatgaa aaatatgcca aaagttgttt tgaattgttt ggttcgaaag taaaaaaatg
    28681 gtttactcat aatgaaccaa tcgttccagt cgaagcaggt tatttatatc gatggcatta
    28741 tccagaagag tcagatatga aaaaagcgat ccaagttggc tatcatgaag cgttggcttc
    28801 agcgttagcc atcaaatctt accatgaaat ggagcaaggt ggtgttattg gtatcatctt
    28861 gaatctgaca ccaagctatc caagagacga atcaaaccct gaagatgtta aagcagcgca
    28921 aatagcagat gcgttcttca atcgttcatt ccttgatcca gctgtaaaag gcgagtttcc
    28981 aagtgaattg attgagatag taaaagaact tgatctcatg cctgtgatcc atgcagagga
    29041 tttgacggtt atcaaagaaa atacagtaga tcttttaggt atcaattatt accagccacg
    29101 ccgggtaaaa gcaaaagaaa caccaatcga tactaaaaac ggtccaatgc ctgaggatta
    29161 tttcgacaat tatgaaatgc ctggtcgtaa aatgaatcct tatcgcggat gggagatcta
    29221 tgaacaagga atctatgata ttttgatcaa tgtacgagat cattatggaa atatcgactg
    29281 ctttatttct gaaaacggta tgggtgtaga aaacgaagca cgatttatca aagaagatgg
    29341 catgatccac gatgattatc ggatcgaatt tgtccaatct catctgaaat atgtccatca
    29401 agccattcaa gaaggtgcca attgtttagg ctatcatatg tggacatgta tggataactg
    29461 gtcgtggacc aatgcatata agaatcgata tggctttatt tcagtagact tagcacaaga
    29521 tggaaaaaga acaatcaaaa aatcgggtca ttggttcaaa gacgtatcag ataaaaacgg
    29581 atttgaggct taagaaagaa tagttgagag caaatgcgtg aaattctcca ttcttaccat
    29641 tttgtgaaaa agaagttcaa ttatttacga tctttttcaa cttttttgtc tttctatttc
    29701 attttttgta tataatagaa tagtcaaaat taaataggag tggaggaaag catgaggaaa
    29761 aaaagaccgt ttcttctctt ttggttattc ggttttttct tactgcttat tttatccgca
    29821 gcattttcag gaaaaatgac agcagatctt gctcagaaag aaacagaaaa aatcgtagca
    29881 agcaaagaat cagtagataa tttcaaaaaa gaattctcaa cttattggtg ggcggagtat
    29941 aaaataactg ccaattacga aaaaggcgaa ttggacattt atttgccaaa aggaaaagaa
    30001 gaaaatcaat ttattaatat cgatgacgta cttagtgcga tttctctcag acaatatcaa
    30061 tttaaagaca agcatttgac cgttttgctt ttgactcatg atggcgacaa agtagcccgt
    30121 ttgaaaaatg gaaaagtgat caccgcttat tctgaaaaag tagacaaaaa agtggtcgcc
    30181 gatcgtttag cggaatggaa aaagacaaat gaacaagtca agaaaacaac tgtctcttct
    30241 caaaaaaacg agtcgacagg aacaagtcct tcagattctg gcagtggaca aacgataacg
    30301 ggaagtgaag aaaatcaagc ctcaattatt acgaatgagt catcacaagg acaatatcaa
    30361 tcctatggac aatgaaaaac agaggttgtg aaatcagcgt tttg
//
LOCUS       DBBGSP010000034        29806 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000034 DBBGSP010000000
VERSION     DBBGSP010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.034"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(227..1114)
                     /locus_tag="ACIZE9_001800"
     CDS             complement(227..1114)
                     /locus_tag="ACIZE9_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6093658.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNKYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1111..1980)
                     /locus_tag="ACIZE9_001801"
     CDS             complement(1111..1980)
                     /locus_tag="ACIZE9_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6093659.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2117..3403)
                     /locus_tag="ACIZE9_001802"
     CDS             complement(2117..3403)
                     /locus_tag="ACIZE9_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6093660.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3676..4254
                     /locus_tag="ACIZE9_001803"
     CDS             3676..4254
                     /locus_tag="ACIZE9_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC6093661.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4254..5183
                     /locus_tag="ACIZE9_001804"
     CDS             4254..5183
                     /locus_tag="ACIZE9_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093662.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5180..6916
                     /locus_tag="ACIZE9_001805"
     CDS             5180..6916
                     /locus_tag="ACIZE9_001805"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC6093663.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="ACIZE9_001806"
     CDS             complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="ACIZE9_001806"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGC6093664.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7812..8321)
                     /locus_tag="ACIZE9_001807"
     CDS             complement(7812..8321)
                     /locus_tag="ACIZE9_001807"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGC6093665.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="ACIZE9_001808"
     CDS             complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="ACIZE9_001808"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGC6093666.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9622..10713)
                     /locus_tag="ACIZE9_001809"
     CDS             complement(9622..10713)
                     /locus_tag="ACIZE9_001809"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGC6093667.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="ACIZE9_001810"
     CDS             complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="ACIZE9_001810"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGC6093668.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="ACIZE9_001811"
     CDS             complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="ACIZE9_001811"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGC6093669.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="ACIZE9_001812"
     CDS             complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="ACIZE9_001812"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGC6093670.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14676..15650)
                     /locus_tag="ACIZE9_001813"
     CDS             complement(14676..15650)
                     /locus_tag="ACIZE9_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HGC6093671.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15631..17514)
                     /locus_tag="ACIZE9_001814"
     CDS             complement(15631..17514)
                     /locus_tag="ACIZE9_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HGC6093672.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17532..19757)
                     /locus_tag="ACIZE9_001815"
     CDS             complement(17532..19757)
                     /locus_tag="ACIZE9_001815"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGC6093673.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19872..20906
                     /locus_tag="ACIZE9_001816"
     CDS             19872..20906
                     /locus_tag="ACIZE9_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6093674.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20973..21986)
                     /locus_tag="ACIZE9_001817"
     CDS             complement(20973..21986)
                     /locus_tag="ACIZE9_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6093675.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22064..22252)
                     /locus_tag="ACIZE9_001818"
     CDS             complement(22064..22252)
                     /locus_tag="ACIZE9_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HGC6093676.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(22692..22820)
                     /locus_tag="ACIZE9_001819"
     CDS             complement(22692..22820)
                     /locus_tag="ACIZE9_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGC6093677.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="ACIZE9_001820"
     CDS             complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="ACIZE9_001820"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGC6093678.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(24307..25362)
                     /locus_tag="ACIZE9_001821"
     CDS             complement(24307..25362)
                     /locus_tag="ACIZE9_001821"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HGC6093679.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="ACIZE9_001822"
     CDS             complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="ACIZE9_001822"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGC6093680.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="ACIZE9_001823"
     CDS             complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="ACIZE9_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGC6093681.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="ACIZE9_001824"
     CDS             complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="ACIZE9_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGC6093682.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(28682..>29806)
                     /gene="ligA"
                     /locus_tag="ACIZE9_001825"
     CDS             complement(28682..>29806)
                     /gene="ligA"
                     /locus_tag="ACIZE9_001825"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGC6093683.1"
                     /translation="KAPRWAAAYKFPPEEVETLIENIEWTVGRTGVVTPTAIMTPVRV
                     AGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVLDKRPKDSEEYQLPT
                     HCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNIDGLGPRVLEQMYDK
                     KLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVERLIFGLGIRHVGAK
                     AAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNEEVHELMNELKQAGV
                     NFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIENLGGKVTGSVSKKTD
                     IVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
BASE COUNT         8254 a         6457 c         5373 g         9722 t
ORIGIN      
        1 gacaatcagg acagtcatcg gcaatatagc agcaatcact tctttaaaat tttttagcat
       61 gtatcctcct cctttactct ttaagtttac cttaaaatga aagagttttc gagcacaaac
      121 ttaaaacgtt atcatttaat ttttctcaac ataaaataac acacgtccca aaagtatctt
      181 tttacttgga aaaatgactt tgaaggaacg cgcttattgt gtttttttat tttacagagc
      241 cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa tacgatggca gttggtaaag
      301 tagcgatgac taatccagcc atgatcattc catagtctgg tgtataggaa gcacccatag
      361 cagataaaac aagcggaacc gtccgtttat caggagattg caaagctact aagggccata
      421 aatatttgtt ccagctactc atgaatgtga tgattgcagc cgcggcatag gtatttttag
      481 ccgtcggcat atacactcta aaaaaaatac ttagttcttt tagaccgtct aatcgagcgg
      541 cttctactag atcttttgga aaagatttaa cattttgtcg aaagaagaag atcaaaaaag
      601 cagtgctaac agatggcagg atgacaacca agaaactgtt gattcccaaa accgttccgt
      661 tcaattgtga aaacattcga tataaaggga tcatcaatgc cgcaaaagga accatcatcg
      721 atagcagtag aatattgaaa attaggtctt ttcgtttact ttgataaatc tcaaatccat
      781 atcctgccat tgacgaaatc agcaatgcaa acacagtggt caccaaagcg atcatcgctg
      841 aattccaaag ggaacgagta aaattcagct cattggaaaa caaattttga aaattgatga
      901 tcaagttact gccaatcttt atttttcccg atgtgatatc cacgggtgta ttcgtcattc
      961 ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga taggatgctt aatgctgtat
     1021 actttaatac tgacccaatt gtcgaacgaa gttctaatgc ttgttttttg acgttggggc
     1081 gttcgattgt ttctttttct accatatttt tcatcgactt tctcctccta ctttcgtttg
     1141 gattatcgac aatatcacaa taaaggaaac aataacaaag gaaactgctg ccgcatatcc
     1201 aaaattaggc gtgaatttat aactcaaatt atagatgtat tgagataggg tggtcgttgc
     1261 atttgctggt cccccgccag taatattttg tacttcatca aaaagctgca atgtcccgat
     1321 cgtcgaagta atggaagtaa acaaaatgat tggttttaaa tttgggatcg tcactttgat
     1381 aaactgctgc catttagaag caccgtcaat agatgctgct tcataaatct ccgaatcaat
     1441 attttgcatg cctgaaagga aaaaaatcat attgtatcca gtccaacgcc aagtgatcga
     1501 aagaatgatc agaactctcg cccaaattgg atgagtcaac cagccaatcg gtgtgtcaat
     1561 cataccaatg cccaacaaca agttgtttac aaggccagat tgagaaaata gacttttcat
     1621 gatcagagaa taactgacca tcgaagtgat acatggaaga aagatagcgg ttcgaaacaa
     1681 ccctttatat ttcaactttt tatcatttaa aaggttggaa ataaaaagtg ctagaaacaa
     1741 catgatcggt acttgtacaa gtaaatacag gaatgtatta aaaaaagctt ttttaaaagt
     1801 tgcatctgtc aacatccgct gataattacc taacccgtta aatgtcatat tgacaggggg
     1861 accactttga aaagacgtga tcaaagccaa aaccatcgga ataaaaacca tgattgatat
     1921 caaaatgact ggcaagatta aaaaagcatg cccgtttttg aataaatctt tctgcttcat
     1981 tcttttccct ccaattctat cattgattat ctacatgaaa agacaagaaa gacaatatct
     2041 gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg atgaaaaagc gaagaaattc
     2101 acttttttac caccgatcaa ttagccaatt gtgcttctac ttgtttttgt gtatctgcta
     2161 gtaccttgtc tgtctcttct ccattgatga ttcgatgaag agcttcagct acgactgctt
     2221 caattgcata ggtctcatgt ccgtaattca cttctggtat ttcagatgtc catgttgaaa
     2281 aatcgtcaaa gatcttttga ccactgtaaa attcagaagc ttcttgataa gcttcttgtt
     2341 cattcgcgct aagcatcgta gatactagtc cgatttcttt cgcaagagtg cccatcagtt
     2401 cttcattcga agcaaacgtt gcttctagga aatctttcgc tgaatcttct ccagctactc
     2461 ctttgatcac ataccagcca gcgccgccaa ggttagaagc ttgcgctttt tgcagatttt
     2521 ctggaagtgc aggtattggt gcaatcttcc attttccaga ttggttttct gctccttgga
     2581 tcgttgaaga ataccaagcg ccagttgggc tagaagctac tgctcctgat tgtatcgcag
     2641 ttactccagc attccagtca gaggtttgtt cgactagatc ttctttcaaa agagtggcaa
     2701 acaattcaag accatacttt aaagatgcat tgtcttggat cgtgactgtc tccccatctt
     2761 cagatgtata ccattctcct gcctgttgca taatcatcct tactcgacca aggtcagaag
     2821 gattgacttc agcgattttc tttcccgtct tttctttgac atctcgcgct acttgaatat
     2881 actcgtccca cttcagattc tccatatcct cttctgtata acctgcttct gccatcagat
     2941 ccgtacgata gaagtttgct gttacgcccg aatcgaaagg aacaccgtat attttatctc
     3001 ctactttgtt taccgcaaat ttatacggtg caaaatgatc ttcctttaca atagcagaca
     3061 aattagcgaa tgcatctgga taagaagtca aatagccttg tatcctataa tcttcaatca
     3121 agacgatatt gggcaatcct tctgtattcc cgctcgctaa agcggtgttc agtttctgaa
     3181 cgatatcatc ctgagacatc gtaacaactt ctatctctgt ttcttcgttc tcataaactt
     3241 tttttgcttc attcactgct ttgatattga atgtctcatc ccacgcccag acagtgactt
     3301 tttcttcttt gtctgctgta ctactagcac ttccgcatcc tgttaagaaa cctgatgctg
     3361 ccgctaaaca aacgactcca gcaattaact ttctgatgtt catttttatc cgctcctttt
     3421 ccatccatta gttgtttacg tttgctacat tcatcatacc aaaatttgaa aacggtttct
     3481 ttattattca gatacttcaa aaatttctcc taaaataata aaaaaataca aatcaactat
     3541 gacaaaagga ataatcttag catctagacc aaagatcgaa atggtgaggt ttctttaaaa
     3601 taaaaatatc cttgcatttt ctcctagaaa taagtatttt taaattacaa gactattctt
     3661 aaggcgggta aaaaaatgcc aatacgcgta attcttatcg atgatgaaca gacgatttta
     3721 gatggaatga aacagttgat caattggtct gagcacgggt ttcaattaat agggactttt
     3781 tccagtccgc tgaaagcgct tgatttttct ttggtacatg caatcgatat cgtggtcaca
     3841 gatgtaatga tgcctgaatt aaatggaatc gaattatcgc ggctattaaa acagcaacaa
     3901 cctgaaacac agatccttat cctctctagc tatgatgaat ttgatatggt taaagattct
     3961 tttaaagaag gcgtcgctga ttatctttta aagcctcgat tgagtcctga tttttttcta
     4021 aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc ccaacaaaag cccaatcacc
     4081 aatcgttatg agcagatctg cgagaatctt tcacagcaga ttgctggaca aactcgtcca
     4141 ttgcttgacc ctcttctttt tgaacacacc ttgtttttct gttatatacc gaaaaacggc
     4201 cattcagttc aaaacaaggc tctaaacaaa aacagtcgat cacccattca ttgatggata
     4261 gcgacgattc gtttactatt tatcctgttt ctaccttttc ggaagaatcc ggctatgtaa
     4321 tcaatactga ttccaaagat acacttagga agtttgttca aaagtttcgt caagaagttt
     4381 ttccaggtga tttttttgtt gtttctgatt cttttgcaat ccaagatatc aatgaaatat
     4441 tccaagagat cagaaattgc accaaaggac aacgtttcta tcataaggga aagaaccttg
     4501 cttatcagca tgaacttctt ccgttattaa ccaaccacga gcagcaagca agtagttatt
     4561 taacaaaaat cgttcataaa gactacgctt tagctgtcaa agaacttgag aatttcttca
     4621 cgacgatatt ggaacagcct attgatccag cttatttgaa acatgaggca atcaatcgtt
     4681 tctatgcatt actcaacgct ttggctgacg agcatgttgg gaatgaagaa ctttctttgc
     4741 tcaagatcgc ccttccttct ttattagccg atgctgagta tttcgaagat ttttctattc
     4801 ttgtcaaaga aacacttgag aaactcaccc acttttctgc aaatgcaaaa aaagacaatt
     4861 tcgatatctt gactttgatc tacgagttcg tccaggaaaa ttatgagaaa gaaatcaatt
     4921 tacaactttt atccgaaaaa tatcattttt catatagcta tctctcagcc atctttactg
     4981 aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt ccgtatcagt aaagccaagc
     5041 tctttttgac ggaaacacgg cttactttga cggaaatctg tgagaaagtc ggctataccg
     5101 aactgggtta tttctccaga gtttttaaag aagagacagg aatgacacct tctcaatacc
     5161 gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag catgaactct ttgccaaact
     5221 tctgttcatt ttgttcatcg gtctttttct gcaagccatc gtcatttctt tgtttattta
     5281 tcatcgatca agggatgcct atatccagct gttcaatcaa tcgaatgatg tggtactaaa
     5341 aaagattcaa tctgaatttg aaagtttgaa tgatacaatc gagaatacat tagccgcttt
     5401 tgattctaat ccagctgtca aaagctattt ttccaatgat ccagcccaac atatggaaca
     5461 gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct ctttcaaaaa tccatccaat
     5521 gatcgattac gatgtattga tctttggaga aaatggaaga acttttgtcg gaaacgacat
     5581 gctcactgcc gtatctgccg attctttttt tcaatctgcg attgctcaga gagtgaatga
     5641 acgtgctgct gatacacaaa tgctttttgc acaccacgga ttgactcttc gcgataagaa
     5701 agcacccagc gtcttctttg tcaaaaaact gaaaaataca ttgaatcacg tttacggata
     5761 tgctgtttta tcgatctcat ccaagcaact agcgaatctt tttcaatctg tagtaaatcc
     5821 tgagatatcg aagatctcct tcatgaacga agaacagacg atcatcgcat caaatgaaga
     5881 aaatacaatt gggagccgat caatgatttt caaaaaacta acagtaggtg aaacaacgat
     5941 ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc caggattgta cattactcag
     6001 tcaagtcgat cttcattctt tatctaacca aatgggcgtg atttttccga ttattttgta
     6061 taatatcgtg acacttgctt ttgctggctc attggtattt atgtatttgg atcgacacac
     6121 aaaatcgatc taccgcttga ttgattcgct aaaacggcta gaggaagatg gcttaaaagc
     6181 tactgttcct gtacaaggaa gccatgaagt ccaattgcta gggaatacga tcaatcaatt
     6241 gctaagtaat gctcagcatc attatgaaca gacgatccaa gacgaaaaga agaaacgttc
     6301 gcttgaaatc caaactatgc aagcacagat acagccccat tttatttata atacgctgac
     6361 tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa gcagttcaag gaatcgacag
     6421 tttcattact ttactaagaa gtacgattgg gaaaaaagaa gaagtgattc cagtcaagga
     6481 agaaatcaaa agcgtacaaa gttacatcga tcttttgagt atgcgatatg gcgaaagaat
     6541 ctcggctaaa ataatgattc ctgatgaact gcagtcatta tctatgccga atatgatcct
     6601 tcaaccaatt atcgaaaacg cctatcttca tgcttttcac aataaaacgc aaggattcat
     6661 cacggtgtac ggcaaaacaa aaaatcagct tcttttattc gaagtgattg ataacggcga
     6721 tggcttcgat actgaaaata ccaaacaaaa aaatgatcat ttttcaggaa tcggcatcag
     6781 ccatgtagat gagcggatac gcctaatgta tggcgatgca tatggcttaa cgatccaatc
     6841 agtgattggg acaggaacga ctgtaacgat ttgtctaccg cttcttccta aaaatcaatc
     6901 agaatatcaa aaataaagaa tagccaagcg ctgatttttt tattttaagt taaataaatc
     6961 aatcagtatt cttgactttc atctacgcgt ctcttctact gtcagcactg gataacagcc
     7021 caatatttga ctttctcctc cgagcatctt gatttcttgg agcgcattct ctactaatgt
     7081 cattggacgg tccaacaaca aatcgatcac gaaaaaatat tctcccaagc tagttttcaa
     7141 tggtcgggat tcaatcttac ttaagttgat ttcccgccag ccaaaagctg ccagcatttt
     7201 atgaagcatc cctggccgat tagcaggtag tgtcaagatg acactcattt ttactggagc
     7261 tgactgctgg ctggtcatct ttcggtcacc gacgatccaa aaacgtgtct ggttcaactc
     7321 attatcttgg atattctcag ctaagatctc caatccaaca tgctgtgctg tttctaatga
     7381 agcaatcgct gctgcgtctt ctttcggatg ttctgctaca tacattgctg cagcagttgt
     7441 tgattctgtt gctactaaag gaacattagg ataatgcgtt tctaaaaact gttgtgattg
     7501 tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt gttgctggat tgcctaaaag
     7561 ctgctgcttg ataggaagaa cgatttcact tttaacttcg acttctggat gtttggaaag
     7621 aagatcgatt gtgtgatgaa cagctccttc caatgaattc tctacaggaa cgacagccag
     7681 atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg atggaagcat acgcagtcaa
     7741 ttgttctgta ggaaatagct gacaagccgc ctgataagtg aatgaacttt ctggccctag
     7801 atagctgacg ttcatatgct tttgatcctt tctataatgg tatcgatgat cttttctggt
     7861 gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt cataccaaga aagtcgttgt
     7921 gccaataatg cttttatttc ttctcttgtt tttccaagag ctaaaggtcg aatagacgtt
     7981 tcatcttgtt ggatacgatc aactagacag tccgcttctg cctctaagta aagaacaatc
     8041 ggctgtgttt ttaaaaaacg ccgattttct gcactttgga caatccctcc accagtcgcg
     8101 ataattttgt cttcatttga cagctttctt aaaatatctg actccacttt tcgaaagctt
     8161 ttttcaccgt aatagtgaaa atattcggca atcgacaatt ggatatgttc ctcaatcttt
     8221 gtatctaaat ctacatactc tttttgtaaa cattgagcta accctttacc gattgttgtt
     8281 tttccagcgc ccatgaaacc aatcagcaaa atgctagcca tgagcttctc ctcctgacac
     8341 aagttctgct aaatcgtcaa aaaatgccgg ataagagatt gaaacagctt cagctccttc
     8401 tagttcgcaa ggtccatcag ctatcaaagc agctacttgc agcatcatac cgattcgatg
     8461 atcgcctctg ctggacactt ttgcgccatg cagaggtgtc ggcccatgga tgatcagacc
     8521 gtctgctgtc gcttttatct ttgctcccat tttctgtaat tcttctgcca ccgcatcaat
     8581 tctgttggtt tcttttactt ttaattcttc tgcgtctttg atgatcgtga ttccttctgc
     8641 ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc agacgcggaa tgatttctcc
     8701 accaatcgtt gctttcttca aatgactcgt cttgacactt aaatcagccg attggttctg
     8761 ttcattgtga ttcgtctggg taatcgctgc gcccatctcc tccaacacat ctaagatacc
     8821 agttcttgtt ggattgaccc cgacattttt taacaacagt tggctttccg gaacaagaag
     8881 tcctgctgct agaaagaaag cagctgatga aatatcacct ggaacagtta tctgttgacc
     8941 agttaatttt tgcggtccgg tcactatgat cgttttatct tccactgtga tccttccgcc
     9001 aaattgacga atcatttctt ccgtatggtt acgggaacgt tctttttcaa cgattacgga
     9061 tgtgccttct gcttgtaatg ccgcaaacag caaagcagat ttgacttgcg cactggctac
     9121 aggcatattg tatcggatag gtgataaaga gcgggttcct gtcacagtga ttggtagata
     9181 ctggtcattt tcttctcctt gcaagtcagc gcccatctcg cgtaaaggtt ccatcactcg
     9241 ccccattgga cgtttagaca acgaagcatc cccgaacaga gtagtcgtaa aaggctgtcc
     9301 agccaaaata cccatcaata aacgtatggt cgtaccggag tttcccatgt caattgattc
     9361 ggttggttgg acaaatgagt ggctaccgcg accatgaatc ttgatcacct cttcctcttc
     9421 ttcgatctcg acacctaatt gttggaaggc atgtaaagta ctcagacaat cttctgcgcg
     9481 caaaaaattt tgtatagtcg tcgttccttc agcaattgct ccaaacatga tgctgcgatg
     9541 ggaaattgat ttatctgctg gtatcctaac agtccctctt aatccatgta tttgttgtaa
     9601 taattgcatt tatccagcct cctatttgat ccagcaatga taactggtat tagacataat
     9661 gattcttttt gcttgtaaca aatcctgttg gtttttaaaa ctgatttgca gtattcctaa
     9721 aatatcttcc ctggtctctt ggatcttcaa attaatcaaa gaaactcccg cttttccgat
     9781 cagtccagtt acttctgcaa taacgccagg ttcatctggc acatcgataa ataaatcaaa
     9841 aaaggcagga atcgcgcctt gcttatggac aggcaactgg tctcgacttt cttttgcccg
     9901 attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg atccattctg ctatttgtgt
     9961 catttcttgt tgccaatctg ccaatcgttc caataatatc tgcttattgc tcaacaaaat
    10021 atctgtccac atgacaggat ctgaggaagc gatcctagtg atatctcgaa agcctcctgc
    10081 tgccagttgt ttggctcgcg gatactcttg attgaattgt tctgcctgat tgactaagcc
    10141 agctgccaga atatgtggaa aatgacttag cattcctgtt atacggtcat gttctcttgc
    10201 tgtaagagtt acatattttg ctttggttcc gcaaaatagt tcttgcagtt tttcaacatc
    10261 ttttttcgtc ttttccaaag gtgtaaagat gtaataggca ttttcaaata gtttagcatc
    10321 tgctgcctgt atacctgatt tatgagaacc agccattgga tgtccaccga caaaccgaag
    10381 atttttctgc tcagcggatg tcacgacttg ctgcttcgta ctgctgacat ccgtaatgat
    10441 gacgtgatca gacaagttga ttctttcaag gacatcaaga taagctaagg ttgtacggac
    10501 gggaacggct aataagataa cgtctgcttg ttctgcacct gtttcaaaat cacttgcaac
    10561 gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt tttgactgac tatcccaacc
    10621 aactactatc agttctggat tggtctgacg aatacaaagt gccatagaag caccaatcag
    10681 tccaagcccc acgataaaaa catgttgtgc catcttattt gccccctttt tagtaatgtt
    10741 tcaagtagtc acggtactcc ttcactgcag ctttcaactc aacaagcgaa tcacttggga
    10801 attttgacaa tagctctgtc gctaccacag tggctacaac attttccgca acgacgctag
    10861 ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc tttgtaaggt tcttttgtat
    10921 cgatatcaac actttgaagt ggcttgtaca atgtaggaat gggtttcatg accccgcgaa
    10981 tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc gcctagatta ttggtacgtc
    11041 ggaaatagcc tctttcttct tcccatagga tctcatccat cacttctgag cctggtaatg
    11101 aaccagaagt gaatccgacc ccaaattcta cgcctttaaa ggcattgata ctaaccacag
    11161 cttgtgcgat tttggcatct agcttcgtgt cccattgtac gtagcttcct aatccagctg
    11221 gaacgcctcc aacgagcact tctacaattc ctccgatcgt atctccattt ttctttgtct
    11281 gatcgatcaa atcttttatt ctttgctcaa ctgctggatc aacaactcgt acttctgacg
    11341 cttcagaaat ttctttgatt tcttgaatcg agatatttcc aggtatttct gcttggattc
    11401 caccaagaca aatcacgtgt cctgctacga tgatgtcaag ttcttccaga attttcttgg
    11461 caattgcgcc gattgctaca cgcatggtcg tctctcttgc agaggaccgt tcaagcacat
    11521 tccgaagatc tcgatgatgg tatttcatac cgcctaccaa atccgcgtgt cctggacgcg
    11581 gacgtgcaac tcgccgcagt gattggtctt tttcaggcac ttctgctaca gacatgacag
    11641 ttgtccaatt tttccaatct ttattttcta ccactaaagt gacaggtgaa ccaattgttt
    11701 tgccgtgacg gatgccagac gtgatccgaa cacgatcttt ttcgatcttc atccttcctc
    11761 ctctgccgta accagcttgt ctgcgagcga gttcgtgatt gatttcttct tctgacagag
    11821 gtaatcctgc tggtagtcct tcaataatgg ctgttaattc tggtccatgg gattctcccg
    11881 cagtcatata acgcatctta cagtcctcct aagtaatctt tgaatgtctc tgtgggaaca
    11941 ggaacgattt ttgcttgccc aatcttttct agcaagatga tattcaattg gcttcctctt
    12001 gctttcttat catgggttat cgcgtggaat aattcatctg gatgacttag atcgtacgta
    12061 atcggcagat ggaatttttg aagtatcctt tctaaagcag ctgtcgatcc agttggagac
    12121 aagccgattt tttctgcatg agaagtgatg gctaccattc caatagctac tccttctcca
    12181 tgactgacta ccccatatcc tgctgtattt tcaattgcat ggccaattgt atgaccaaaa
    12241 tttaaaataa gtcgatttcc ttggtcaaag acatcttctt ccactacttt tcgtttgatt
    12301 tccaacgtag cagtaatgat tggaacagca tgttccagaa gatctttttc gtctttcagc
    12361 tcgttcagct gtttccaaag cgttgcatct gctatagctg ctgatttgat gatttcagcg
    12421 attccttctc gtaaacgacg taccggcaaa gtttttagaa cctcaggatc aatcaataca
    12481 ccagctggct ggctaaatgt tccgacaagg tttttcgctt tgtttgtatt gactgctgtc
    12541 ttcccgccaa tactagaatc tacttgtgca agtagcgtag tcggaatttg aacgaaatgg
    12601 atcccacgca tgaacgtcga ggccacgaat gctgctagat cacccaccat tcctccacca
    12661 agtgcaagta tcccatcgct gcgggtaaaa tcattatctg ctaaaaaatc gtataactca
    12721 gctgcttgtt ctaaagattt actggtctca cccgccggta cgattgaaag gactggttca
    12781 aaattagctt gtctcaattg gaacatgatt ttttctgcat atagtggagc aacgtttgta
    12841 tcagtgatca cagctacttt ttgaggtctc caaatcgttt gaagccatga tccagcctgt
    12901 tctagtgcgc ctttttcaat atgaatatcg tatttttggt tatcaacatg tacagtaagc
    12961 attcgtttca cttctttctt ttaaaaagct ggaattaatc gagtgtctga atcttttcca
    13021 ttgcttcttt catgatcgca acttctttca tcatgcgtga gtaagtcttt tcattcaacg
    13081 attggggacc gtctgaccaa gcatttgcag gatcaggatg gatctctacg atcatgccat
    13141 ctgctccgct tgccacaccc gcacgagcca ttggtggtac aagttcccaa attcctgtac
    13201 catgacttgg atcaacaatc acagggaaat gagttaattt tttcatcaat gggacagcac
    13261 ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg aatcccacgt tcgataaaaa
    13321 tgacaggaga tttgtcttcg actgcaatgt attctgcagc attaagccat tcattgatcg
    13381 taccggaaat tccacgtttc aatccaacag gtttacctgt tttaccgaca gcagatagca
    13441 gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat atcgctgtac tcagccacca
    13501 tatcgatatg cccttcatcc atcacttcag taatcacttt cattccaaat tcatcagccg
    13561 cttgacggat gtatttcaat ccttcttctt ctaaaccttg gaaagcatat ggagaagtac
    13621 gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc ggctttggcc attcgcgcac
    13681 attctctgat ttggtctaat ccttcgatag aacaaggacc agccatcgtc acgaaactgc
    13741 cgtcaccaat ttttactccg tctacatcca cgactgtatt gccaggatgg aattctcgag
    13801 aagtcaattt gtatgtgttt aaaatacgca cagcattttc tactccttca tagcgtgtaa
    13861 atgctccttc ttgtaaactt cgcgtatcac cttttagtcc aatcactact cgttctgttc
    13921 cttgatcgat tgagactttg aatccttctt tttcgatatg atcgacgact ttttttattt
    13981 gttcttccgt tgcttctttt ttcataatta ctatcattgt ttttcccgct ttcttttgtt
    14041 tacttatcta tcttggctga ttttctctac tttttcaagg tggttttaca ttaattccta
    14101 ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc tttcctactt atgacccaga
    14161 taatcaacaa aaaaagatgt ccctgtagga aattgcctct acagtgaaca tcttcaacga
    14221 gccttaaaaa gcgctgcaaa aatataaaat agccactata gatgaatttc tctacgtggc
    14281 tgtaagtcgt gtttaaaaat ctttagccat catagataca aacctggttt gtttgtaccc
    14341 acgaagtcat gaatacaaac ctatctaaaa tagctaaagt aatacgtatt cagttttgta
    14401 agttttctag atttcataaa aaatcgctcc aaactgatgt aagaattgta cctagtatag
    14461 acataaaaaa atcgactgtc aatcattttt atgaaacttt ttttaatttt ctgatagtta
    14521 actttgtttt tcagaaaaat aacaattggt tttattgaag aaaatagtca tgaacaaaag
    14581 tatctgagaa cttttttact ctcttgttca tgacatatag aataaagcag ctttgtcttg
    14641 taaactccgt ttttcaaata ataatctaaa gattgctact gaataataaa gccgatttca
    14701 tggtcctctt cgctgctgat tcggtaaggt gactcaacat ccgctcccca gctattgata
    14761 cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg ttcgtctttc tggcggtagt
    14821 tcttctatat gtgttgcctg ttccagttct tctgctttga atggtaaagc ggaaaaagca
    14881 aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt cttgatcttt atccgtatta
    14941 tccaacgttt gatttcttgt tagttctacc catttcgttt ccatatgcat gccgcattct
    15001 tggggaacaa ggtatgggga aacggggagt cctgccactt tataaatacc ttcgacacca
    15061 ccagccatcc gatccggata tgtttcccct gataggcctt catactcaaa aaattttgct
    15121 ttcgttggca taatgaacct taaacccaat gcgggtaatt ccggtaatcc tttttgtcca
    15181 taataatgca tattgacaag cattttaccc tctccagcga tttggtagga aattgtcact
    15241 tgggtttttg gtactgtgtt gatttccagt gtaaaaatga tttcaaccgt ttcagcgtat
    15301 tcattacttg aatattgatt atttactgga gcaatcggca aatcgatctt tttattgtcc
    15361 accagtactt ctatttcttt gacttttgga tacaatccgg ctcctaacca cataccggat
    15421 ttaaatccaa atccgctacc tctgtcatta tcggtcgttg ctcgccaaaa aactggaagt
    15481 gtttcccggt atagccattc ttttccgttt ttattgagcg attccagtcc gcctcttgta
    15541 taagaaaaaa tataatgcgt attccccgat ttgacaccta atgtacagtc gccgaagacg
    15601 attgcaactt tttccgtatc catatgactt ttatttactg tatttttcat aataatatct
    15661 tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa acgatcccat tccctgagaa
    15721 ttcatagtca cttggtttat cgtcaaagtc accgccatag cgcatcactt ctctgcctgt
    15781 gattggatca gtcacttgga tcgcctgatc tttaaaatcc catatatagc ctccttggta
    15841 catttcataa cgatcaagca acgtcatgta agaatccatt ccacctaacg aattccccat
    15901 gtcatgcata tattcacata agatgaacgg tttttccgct ttattttcaa ggtagtcaat
    15961 gatctcttct ggtggcgcat acatgcagct ttttacatct gaaatcgaat cttcgaatgc
    16021 tggatttgga aaattccctt cataatggac aagtcgatcg gggtctactt ttttgaagta
    16081 atcgttcatt tgtcgaatgt tttcttccgc ataagattca tttccaagag accaaaaaag
    16141 aatacttgga tggtttttta atgtttcgaa attcgttttt gctcgatcaa gaacagccgc
    16201 ctgccactga ggtactgcac ctggtacgtt gtaagaaggc tcaaatgcgc ccattttttg
    16261 ccatgagcca tgggattcga ggttcgtttc cgccatcaca tggattcctg cttggtcgca
    16321 taaataatac caagtgatct ggttggggta atgagatgtc cgtacgccgt tgatctttgc
    16381 attttttatg atagccaaat ctttttccat atcttctata gtgatggcgc gtcctttttt
    16441 cggatgccac tcatgtcgat ttaccccgtt gataatcatc cgttttccat tgaagtagat
    16501 gattttatct ttgatttcga ttttacgaaa accgaaggaa tagtcaatat actccgttac
    16561 tcttttttct tcgtctatcg tctccaattc aagcttatat aaattgggct gaaaatgccc
    16621 ccacagtgcc acattttcaa atccatcgat gcgaatcgtc atttgctctt ttaacggata
    16681 ttgctgttga tagatttcct tcccatcagg atctagtatc gctacattca gctgactgtt
    16741 tttggctact tgctcaaaag acaaatctac ttcaagtttg ccattttgac atttgtcatc
    16801 taagcgaggt ttgatccaaa gatcttctaa atggttttgt cctcgagcaa ctaagaagac
    16861 atctctgaag atcccaaaaa atcggaaaaa gtcctgatct tccaagaatg cagctgtact
    16921 tcttttgtaa acctccacag ctagaatatt ttcttcttcc aaataaggtg ttaaatcaaa
    16981 ttcagacgga gtgaacgaat cttcggcata cccgataaaa tgaccattca accaaataaa
    17041 cattgcttgt tctacaccag caaaatgaat cgagatttgt tttcccttta gaccttcttc
    17101 taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct ttagcagctg aaaagatccc
    17161 ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg cgaaatacat gtccctccca
    17221 cggatacatc gtattgatgt aatggatctt gtcataattt gctaattcaa tatgactagg
    17281 aacagtgatt tcatcaaaag aacaggcatc aaaatctttt ttataaaatg tttttggtcg
    17341 taccgaagga tttggcgaat aacaaaaacg ccatgatcca tttaaagact gtttaaggga
    17401 ggatgtggtt tctacttctt cccttgttgc ataacaaaca tgatcgctat gtgcatttga
    17461 ttggttcact ctaaaaactt gtggatcatc taaccatttt atatttgctt tcatactttt
    17521 ttccttctct ctcataactt tttgaaatga agcagttctg tttggaaatc accttgaaaa
    17581 tcggggaagt aaagtccaac tgtcatcaat tcggcccccg aaaatatccg cttcgaggtc
    17641 tgttcctgat aaagtgcctc atcatctaac cccatcagat atacttcatg gaacgctggt
    17701 tgagctgaag ctagtatcct ccctaaaaac acaatagctt catcttgttt aggagacaca
    17761 aacatccatg cggcaatatt ttcttcaaaa ggactcgcca aacgataata atggccatac
    17821 tggatcaccg gacgaatcgt ttgataggat ataatttggt cttttacttg ctttttttct
    17881 tcaggagaca gctttgtcaa atccagttca taaccaaaaa cagcgctcat agctgtttct
    17941 cctcttgttt tcaacgaagt agatctgtcg gtctgatgat ttggtacagc tgatacatga
    18001 gctgtgatgg acgaaatcgg ataagcaagg cttgttccat attggatttt catacgctcc
    18061 actgcatccg tgttatcact tgtccatgac tgcggcatat aataaataaa cccggcatca
    18121 aaccgtccac ctccaccaga acagccttcc cataagattt ccggataatc agttgtcaaa
    18181 tgttcaagta gttcataaag cccgagcata taacgatgcg ctacttctcc ttgtctctgt
    18241 gggtcaaggg taatcgaata gacatctgaa agcgaacggt tcatatccca tttgatgtag
    18301 tcaagaggaa tcgtatctaa aatctttctc atttgtttct caatcgtctg ccgaacatct
    18361 aaccttgtaa aatccagtac atgttgtgat ctggaagcag aaggcattct acctggctcc
    18421 tgcataagaa aatcaggatg tgttcgatac agttcagaat caaccgagat catttcaggt
    18481 tcaaaccata aaccaaattt caatcctttg ctatgagcat aatctgctat ttcacgtaat
    18541 ccatttgtca acttgccttc atactcgaac cagtctccta atgaagaatt gtccgcatct
    18601 ctttttccaa accagccatc atctaatacg aacatttcga tgcctagctc ctttgcttca
    18661 tcaatgatcg ccttgatttt ttcactattg aagtcaaagt aagtggcttc ccagttattg
    18721 accagaatcg gccgttcagc aaattgatga cgacctcttg cgattctttc acgtagcaac
    18781 tcatggtgga tctgactcat tttgttcaat ccctgacttg agtaagaaag gatcatttca
    18841 ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa aacgatggct gttgatccca
    18901 ccgacgactc tcaattgatt gatctgatct ttttcaagtt cgaaagaatg gttgccggaa
    18961 taaacaaatt gaagtccgat cgcttctcca gtattttctg tcgtatgatg atgaactaaa
    19021 gcaataaagt tattcatatg gtgactgctc gttcctcgac ggctttcaaa tacttttgtt
    19081 ccagataaaa cagattgccg tgaaatctgt ctttcattga catgtgctcc tggcaaagca
    19141 atgacttcat caaatcgcct agtatgggca aagtctagct ggaaactagc cgctttttct
    19201 agtttgattg tttctccggt ttcatttctt atctttacag atcgtgtgat cactgctcta
    19261 tcagtaaata tggtatagaa caaatcgaaa taaatcgctg tttctctatc cttaagtgaa
    19321 atcaccaacg tttgtgcctc tgacttgtcc atcacataag tttgaggcaa gccttcgatc
    19381 tctggcttcc catctgtaat ataatggctg tcatatctca gatccagtaa gtctgatcca
    19441 ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca tgctgccatg agaagagtat
    19501 tcttgcggta gtgtatcttt cgacagagac cggtcaggat ttaagggaac atttcctgaa
    19561 aatccacgat ctcttcgggg ataattttta ttgtctttgt actgcttgac tggtttgcca
    19621 aaataaatat gcgccaatac attgctttct tctatcttta tcagataaga aagaaatgta
    19681 tttcgtaaat ggaagactcg gctcttttca tcaaataaga tgaaattttt atctgttttt
    19741 ctatgcgtaa tatccatcat ttcactccca acaaaacgga aaccgtttac ttttttttat
    19801 aattcctgta tactgtttac taaacaattt tgtcaataaa aattttttat ttttttgagg
    19861 agtgtgtaaa aatggttgga attagagatg tcgcacgaaa ggcaaatgtc tctcctgcta
    19921 cagtttcccg tgtgttgaat aacgatcaga cgatccatgt ggctcagact actcggcaac
    19981 ggatagtaga ggcagctgct gcgttggatt atgacatcag tactcgtaaa tatatcaaaa
    20041 agagaatgcc ttcgattggt gtgatctcta cgatcggcaa agcgagcgaa gaacaggata
    20101 tctattacaa acatttgcga gtagggatgg aagaagaagc tcgacgtctg catttaggga
    20161 tgaatcgaat ctataatcta tctgataatc ctaaacaatg ggaagatcta gatcagttag
    20221 gtgcggtgat cgttgttggg actgttacga aagaatcgat taccgccttg ttaaaacaaa
    20281 acatgcaaat agtcgtcgtg gataaccctg acatccagca agaggtcgat atggtgtatg
    20341 cagatcttga acggatgact aaaaccgtac tggaattgtt cttagaaaat ggtcataaaa
    20401 gaatagccta tatcggggga tataaagtcg atatggatga attcggtggg aagcagattt
    20461 ctataaatga aaagaggatg cgtgcctatc agcattttat gatcgatcat cacttagaaa
    20521 aatatatgtc ttatcatcta ggtggctgga cagaaaaaca aggtgaggta cttgcgacta
    20581 atctattaga aaatgaatcc cctcttccta ctgccattct tgtcgggagc gatccaatgg
    20641 caattggtgt ctatcgggca ttgaaacaaa aaaatatcca aattggagaa gagattgttg
    20701 tagcaagctt tgataatatc gagacaatcg caaacctctc ccctggcttg accagtgttc
    20761 aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat ggcattggag cgaattgacg
    20821 gtatacggga cgaaccaatc attttgactt atcctgcacg attgattgtt agggaaagtt
    20881 ttatcccaag aacaaaaagg tattgaaaga gaggttgtga aaagccgctt cgtttcttca
    20941 tactcaaaac gaaacggctt tttcacaacc tcttacttat acttattcac aaaatccaat
    21001 gtctgctggt aacaattttg cgattctttt agcgtgtaat caaattggta ttcatgggta
    21061 atctcttttt ttgtatctgt ataaaacaag gattgcacgg gtacctttaa ttctgtcaac
    21121 cgattttcta atgcttgacc ttgctcctgg aatgagtatg catttccgtc agttatatac
    21181 gttggcggaa attccttaga aacatggtca gccacactag cttctttcaa ttgctcactc
    21241 gttttccaat cttttgttcc aatcaacgac cacgcaacgg ttttgacgaa aaacttcata
    21301 aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat caacaggtcc gcaataagaa
    21361 atggttcctt tcagactatc ttttggaagt agctgtttga ttttcatttg tttagcatac
    21421 gcatcattcg tttgtatagc tgcatattgc aatgcgattt gtgaacctgc actatctcca
    21481 ccaaaaaata attgttccat gtctagcaat ttgtcgtctt tttcttcagc taataaatct
    21541 ttgatcagtt cattcacttg aagaacttga ttagggtatt ctgaatcagg cgctaattca
    21601 taattcatcg caaccactgc gatgttggcg tctgaaacta attttgtcgc aaattctttg
    21661 acacccgatt tatctccgcc gacgaatcct ccaccatgta cccaaaatag aacaggaaca
    21721 ggccccttgc tgttttttgg atagtagatg tcataagtat tctctttata cttggactca
    21781 tacgtcaaat ctgttttttt cgccacgttt ttttctgctt gatcgaacgt ttttttatca
    21841 gtgatttgaa cagtatttga aaacatatgg ttgatcaaga atgctccagg tctgggggaa
    21901 agctggaagg caagaaagat tgcaaacgcg atcccaagaa tgattccgaa gaaccatccg
    21961 ataaatttaa gaattttctt tttcataagg ctccctcagt agttagtatt aagcattctg
    22021 attataccat agtgttattt cctatcaagc tctcctagat gatttaatga ttttccccaa
    22081 acttcttctg caatgctttt gacaaaagaa attttttcca ttgttcttca aacaaaacat
    22141 tttcttcttc tgttgaagca aatccacatt gaggacttaa gcacaaacga tccaaaggca
    22201 gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg gtgctcttcc atttcgccat
    22261 ttttcgttac agtcaaaatc taagacaact aatttatctt cagagacttt ctctaaaaga
    22321 acaaaactcc cagcacgttc actatcgtat tctaaataat aggcacggac attttcttga
    22381 gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg ccgccaaaat cgaataataa
    22441 tttccgcgtc aaacatgtat atttagtgtt gaatcatttg agaatatgaa aataaaaatc
    22501 tttttgatca atcagttaat caaattgaaa taacgaaaaa tctgagacag aatgacgttc
    22561 attctgaccc agatttgatt ttgcacaact caacagtcct tattggcaaa tcgccaaaat
    22621 aatgtagact aactaaaaag actaagaaac aataacaaaa gttaacactt cttagtcttt
    22681 ctttagcacg tctatttatt aaagatttta gggccttttc tcatgttttt acgatcattc
    22741 ttaggtgttt ccatttgttt ggatcggcct ccaccttgtt tctttttgat caattctttc
    22801 attttttctt tttggtccat ttttattctc ctttaacgaa tgaagcgact aattcgatat
    22861 gatgggtttg cgggaaaaga tctacaggct gaactttctt cacggcataa cctgcttctg
    22921 caaataactt agcatctctt gcaaaagttg ccggattaca tgagatatag acgattcgtt
    22981 ctggtgacat ttcgattgct gattcaataa aatgatgatc taatcctttt cgtggagggt
    23041 caactacgat cacagatggt ttgatccctt tttcttgcca ttttttcata actttttctg
    23101 cttttccgac ttcataatga acattttcga ttttattatt taaagcattg aactgtgcat
    23161 cttcaattgc ttctggaata acttccatcc catacacctt atccactctg tctgctaaag
    23221 acaagccaat cgtacctatt cctgaataag cgtcgatcac aatgtctttt ttatctaact
    23281 cggcaaactc gatggctgtt tggtacagat actctgcttg ttgagtattt acttgataaa
    23341 atgactttgc tgagattcga taggtttttc ctaatagctg atcttcgata tagtctctgc
    23401 catataaaac tttttctttg tctcctaaaa tcacatttgt tttttcttca ttgatatttt
    23461 ggatgaccga aaccacttct ggcaattctt catgaatagc ttcagcaatt tccttggatt
    23521 taaagaattt ttctttacga gtaactaaaa cgaccatcat ttcatgggaa taatgaccac
    23581 gacggataat gatgtgacga agctgtcctt catttttttc ttcattatat cctcgtactt
    23641 ggaaccgttg caagatatct ctgactactt tgattgcttg atcgatgaca ggatcttgga
    23701 tataaaaatc ttcgataggg actagatcat ggctattctt tttgtaaaaa ccggtggcta
    23761 actgtccatc gatacggcga acagggatct gtgctttatt acggtagccg aatggttctg
    23821 ccattccgac cgttggaagt acaggaactt ctggcatctt agcaatcttc gccattacat
    23881 gctctacttg tttttgtttg aagacaagct gttgttcata cttcaaatgg gctaaaggtg
    23941 cgatacctat gcgaagtaat gcattgtttt ctacaggctg acgatcaggt gattgtgtaa
    24001 taaatgtttc gacttttcca tatccaaact tattgcctgc ttttactact agtatttcta
    24061 cttcttctcc agggagtgca ttttcgataa ataatggata accatcgatt tttgctaccc
    24121 ccattccttc ataactcaag tcgacgattt cgactgtata tcgttcgttt ttctttacta
    24181 tttgctgttc tgtcatattt tgctccttta agcctatttt tcaatcctac tgaactctac
    24241 tataaatcag ctaattacac aactaaaacc ggcactgacc ttactacgtt cagcaccggc
    24301 ttttgattaa ttcttttgat taggtgtttc gtctgctatt tttccgtcac cgtcgatatc
    24361 ttcatccgtt aaacgttcga cttcttttac gaattctttg ctgacaacct ctaattcttc
    24421 ttcatctgta cctgtgattg cttcatcagg aatctgatcg gtattggcaa agaactcaat
    24481 gtgttgatga agattttgga aatgcatcgg tgcttccccg ccgtattcac catctaagtt
    24541 gatcattact ggtcgattga tatcatcttc tgtttcaacg aacaaactgc ttgttttggt
    24601 atagattatt cttggatcat cgacatgtcg accgccattc agcatgagtg ctgcaatatg
    24661 caagatctca aagatatttg ctgtcttcac aatgattaaa gaaaacttcc catcatccaa
    24721 tttggcatct ggcgcgatct gttcgaatcc tccaacagag ttcgtcagcc ctaggaaaaa
    24781 catcgaagca tttccgatat attccccttc atcatacttc aagcgcattt tgattggctt
    24841 tactcgaggg agcatctctg ctcctttcgc aagataagca agataaccaa aaatactctt
    24901 tagttctgat ggaacttcat aagtcaattc tgtcaaatag ccacctgcag cgatattgat
    24961 gaagtaactg ttatcagaaa ggccgatgtc catttttacg gtttggtgtt tttttatcac
    25021 ttctgctgct gctttaatat tatctctagg aatttttaat gctcgagcat agtcgttcgt
    25081 tgtaccagct gggatgatgg ccattttagg acggtgttca agcggagcga ttccattaac
    25141 cacttcgttg attgtgccat cgccaccagc tgccactact agatcaaaac ctagttctgc
    25201 gactctacat gcttcattct tggctgaatc tggttctggt gtagttgcat aggcgctggc
    25261 ttcaaatcct gcttcttcta atgcctgtag gatatccgcc aaattttttt tcaataattc
    25321 ttttcccgag gtggggttat aaattacgcg tgcttttttc attttcagcc tctatcgttt
    25381 cgctaattca tctttaagta gcttattcac gacaccagga tttgcttgtc ctttagttgc
    25441 tttcatgatt tgaccgacta ggaagccaac cgcacgatct tttccatttt tgaaatcatc
    25501 gacagattgt tggttgttat ccaaaatttc attaatgatt ggcagtagtt tgttcggatc
    25561 agataattgc acccaaccat ttttttcaac tacttcttgg gcttctccgc catttgtgat
    25621 caattcacgg aagacttttt tggcgatttt tgagctgatc gttccatcgg cgatcaaacg
    25681 aatcattcct gctaagttct caggtgtcaa ttttgtctca gctaattcca gtttctcact
    25741 gttcaagtaa gcagaaactt cacccatcaa ccagttagat gcttgcttgg catctgcacc
    25801 attttccaaa acagcttcaa aaaaatcaga catttctttt gtaagtgtca ataccattgc
    25861 gtcatactct ggaagtccaa actcacggat atagcgttcg cgacgagaag ctggcatctc
    25921 aggcaaacta gcttttactt tttgaatcca ttcgtcatcg atcacgaatt tcgggatatc
    25981 aggctctggg aagtaacgat aatcactaga cccttctttg acacgcatca aaactgtttt
    26041 attcgttgtt tcgtcaaaac ggcgtgtttc ttgttggatt tctcctcctg aaagaagaac
    26101 ttttgcttga cgtttttctt caaaagctaa accttttttc acgaaagata aagagttcaa
    26161 gtttttcaat tctgctttcg taccgaactc ttcttgtcca taagggcgaa gagaaatatt
    26221 ggcatcacag cgcatagagc cttcttccat tttcacatcg ctgacttctg taaattggat
    26281 aattgatcgc aatgcttcta gataagcgta tgcttcttct ggtgaacgca tatcagcttc
    26341 agaaacgatt tcgatcaaag gcgtgccttg tcggttcaaa tcaacgtaag aataaccgcc
    26401 aataccatgc atgttttttc cagcatcttc ttctaaatgg acacgttcga tccggatttt
    26461 tttcttttta ccttctactt cgatttcgat ccatccgtca tgaccgattg gttgatcaaa
    26521 ttgggaaatt tgatatgctt ttggattatc tgggtaaaag taatttttcc ggtcaaaatg
    26581 agtatcttta gagatttcac agtttaatgc caaagctgct ttcatcccga attccagcgc
    26641 agctttattc attactggca gcacgcctgg ataaccccag tcgatcacgt ttgtattgct
    26701 gtttggttct gcaccaaaat gagctggcgc tggagagaaa atttttgagt tggtttttaa
    26761 ctcgacgtgg acttctagtc caatgactgt ttcaaaattc attcgtcttt ccctcctaaa
    26821 atagctggtt gttgtttatg gaattctgtt gcttgttcaa acgcatatgc cgcttgatac
    26881 atcgtttttt catcaaaata attaccgatg atctgcaatc caactggtaa tccttctgat
    26941 aaacctgccg gtacagacat acctggaagt ccagccaagt tgacagggat cgttaagatg
    27001 tcactcatgt acattgtgat tggatcgtta atgttctcac cgattccgaa tgcaactgtt
    27061 ggtgaagatg gcccgatgat caagtcataa tctgcaaaga ctttttcaaa atctcgtttg
    27121 atcaatgtac ggacttgtcc tgcttttttg aagtaagcgt cataataacc cgcgcttaag
    27181 gagaatgtac ctaacatgat acggcgtttt acttcttcac cgaatccttc tgaacgtgag
    27241 ttgacatata catcatctaa tgatttcaca ttttcagagc gataaccgta gcggatacca
    27301 tcgaatcgtt gcaaattgga acttgcttct gatgaggcaa tgatataata aacagccaca
    27361 ccgtattttg aatgaggcaa gctgacttct tccacaacag cacctaatga acggaatgtt
    27421 tctgctgctt tcaatacagc ttcttttacg ccaggggcca caccttcgcc taagtattct
    27481 ttaggtaaag caatcttcat tcctttgatg tcgcctgtca gtccctctgc aaaatcagga
    27541 actgaaacgc ctgaagaagt accgtctttt tcgtcataac cgctgatagc tgtcaatgct
    27601 aatgcattat ctttcaccgt acgggtcatt ggtccgattt ggtcaagaga tgaagcaaag
    27661 gcaatcaaac caaaacgtga gacacggcca taagtaggtt tcatccctac gatgccgtta
    27721 aaagctgctg gttggcggat acttccccca gtatcactac ctaaagaaac tggaatttgt
    27781 ccagctgcaa ctgctgctgc agaaccacca gaagagccac caggtacttt tgttgggtcc
    27841 caagcatttt ttgttttctt gaaataagaa gtttctgtac ttccacccat agcaaattca
    27901 tccatgttta gcttaccaac agggatcata tctgcttgat agattttatc catgaccgtt
    27961 gcatcataaa ttggttcaaa attgtaaagg atcttagatg cagcggttgt caagatatct
    28021 tttgttacga tattatcctt gataccaatt ggaataccag caaggacgtt gctttcatca
    28081 atcccttttt catctaaagc ttttgcctgt tccaatgctt tttcttcgtt caatgtaatg
    28141 aatgcctcga cctcaggctc tgtttctttg attcgttcaa atgttgtttt tgtcaaatct
    28201 tgtacagtga tttctttcga tacaagcata tgatgcagtt cttctagaga acgattgtgt
    28261 aattctgtca ttatgcgcca gcctccccat tatcgatgat tgcgggtact ttgataaagc
    28321 cgtcttctgt ttccggcaca tttttcaata attcatcgcg gttccatcca gcttgcgccc
    28381 gatcttgtcg catcacgttt actgtttcaa ccacattcga cgtaaatgga acaccttccg
    28441 tatctacttc ttccagcatt tcaaccatat cgatgatttt acctaattgg tcggtaaaac
    28501 ttgcaagttc ttcatctgcg aacgcaagtt ttgctaattt ggcaacgtgt ttcacttgtt
    28561 cttcactaat cgccatacta ccccttcttt ctaaacgagt taaaaacttt gctctctatt
    28621 ttaacacaag agtgccgtgt ctgaaattgt ttattgaaat ttgtctgaaa aaactcattt
    28681 ttcattcttc tactgagcga cttttagcca atgcatctgc catttgatct tctgtccaaa
    28741 cttcgattcc taattcttgt gctttggtca gcttgctgcc agcatcttct cctgctacca
    28801 cgatatccgt ttttttcgat acgctaccag tcactttccc gccaagattt tcgatcgtct
    28861 cttttgcttc ttcacgagta aatcgtgtta gtttaccagt aaggactact gttttttctt
    28921 taaaaggaga ctcgacttct tgcaattggg catttcgaag ccctttgtat tcgaaattga
    28981 cgcctgcttg ttttaattca ttcatcaatt catggacttc ttcgttactg aaataagtga
    29041 ctacactgtc ggcaatgata tcaccgatcg tatcaagcgc aataatcgac tcatagtcac
    29101 ttttactcaa tgtttctaga tcaccgaaat gttctgctaa aatttttgct gctttcgctc
    29161 cgacatgtcg gattcctaac ccgaaaatca accgctcgac cgaattatct ttgctgttgt
    29221 cgattgctgt caaaatatta tttgctgatt tttcttttat tttgtccaac gtcaataact
    29281 cttcttctgt caatttgtaa agatcagcaa catctgctac tagtttttta tcatacatct
    29341 gttctagtac gcgcggcccc aacccatcga tattcatcgc atttcttgaa acaaagtggt
    29401 tcaaaccttc tttcatttga gcagggcatt taggattgat gcaccgtaag gctacttctt
    29461 catccaaatg gacaagttca cttccacaaa ctggacaatg tgtaggcaat tggtattctt
    29521 cgctgtcttt aggtcgttta tctaacacga cttgcgaaac ttctgggatg atgtctcccg
    29581 ctttataaat cagaactgta tctttcaagc ggatatcctt caacttaata taatcaccgt
    29641 tatgcaggct ggcacggctt actgtcgttc ctgctactcg gactggtgtc atgatagctg
    29701 ttggcgttac tacccctgtt cgaccgactg tccattcgat gttttcgatt agcgtttcaa
    29761 cttcttctgg cggaaacttg taagctgctg cccatctcgg tgcttt
//
LOCUS       DBBGSP010000035        29307 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000035 DBBGSP010000000
VERSION     DBBGSP010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29307
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.035"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            141..398
                     /locus_tag="ACIZE9_001826"
     CDS             141..398
                     /locus_tag="ACIZE9_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093684.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="ACIZE9_001827"
     CDS             complement(630..1061)
                     /locus_tag="ACIZE9_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGC6093685.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
     gene            complement(1412..2110)
                     /locus_tag="ACIZE9_001828"
                     /pseudo
     CDS             complement(1412..2110)
                     /locus_tag="ACIZE9_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            2189..2365
                     /locus_tag="ACIZE9_001829"
                     /pseudo
     CDS             2189..2365
                     /locus_tag="ACIZE9_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(2541..3110)
                     /locus_tag="ACIZE9_001830"
     CDS             complement(2541..3110)
                     /locus_tag="ACIZE9_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGC6093686.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(3184..3507)
                     /locus_tag="ACIZE9_001831"
     CDS             complement(3184..3507)
                     /locus_tag="ACIZE9_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093687.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(3661..4473)
                     /locus_tag="ACIZE9_001832"
     CDS             complement(3661..4473)
                     /locus_tag="ACIZE9_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093688.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            4800..5675
                     /locus_tag="ACIZE9_001833"
     CDS             4800..5675
                     /locus_tag="ACIZE9_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6093689.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            5689..6012
                     /locus_tag="ACIZE9_001834"
     CDS             5689..6012
                     /locus_tag="ACIZE9_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093690.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            6009..6761
                     /locus_tag="ACIZE9_001835"
     CDS             6009..6761
                     /locus_tag="ACIZE9_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HGC6093691.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            6751..8922
                     /locus_tag="ACIZE9_001836"
                     /pseudo
     CDS             6751..8922
                     /locus_tag="ACIZE9_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(9034..11205)
                     /gene="copB"
                     /locus_tag="ACIZE9_001837"
     CDS             complement(9034..11205)
                     /gene="copB"
                     /locus_tag="ACIZE9_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HGC6093692.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(11225..13411)
                     /locus_tag="ACIZE9_001838"
     CDS             complement(11225..13411)
                     /locus_tag="ACIZE9_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC6093693.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(13411..13620)
                     /gene="copZ"
                     /locus_tag="ACIZE9_001839"
     CDS             complement(13411..13620)
                     /gene="copZ"
                     /locus_tag="ACIZE9_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HGC6093694.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(13633..14073)
                     /locus_tag="ACIZE9_001840"
     CDS             complement(13633..14073)
                     /locus_tag="ACIZE9_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGC6093695.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(14147..14686)
                     /locus_tag="ACIZE9_001841"
     CDS             complement(14147..14686)
                     /locus_tag="ACIZE9_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HGC6093696.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(15301..16767)
                     /locus_tag="ACIZE9_001842"
     CDS             complement(15301..16767)
                     /locus_tag="ACIZE9_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGC6093697.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(17078..19159)
                     /locus_tag="ACIZE9_001843"
     CDS             complement(17078..19159)
                     /locus_tag="ACIZE9_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC6093698.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(19301..19423)
                     /locus_tag="ACIZE9_001844"
     CDS             complement(19301..19423)
                     /locus_tag="ACIZE9_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093699.1"
                     /translation="MNLDKLPATGFKLSCYPVKIKKASAGWIRAVAMIEKKKKE"
     gene            complement(19683..20042)
                     /locus_tag="ACIZE9_001845"
     CDS             complement(19683..20042)
                     /locus_tag="ACIZE9_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HGC6093700.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(20072..20413)
                     /locus_tag="ACIZE9_001846"
     CDS             complement(20072..20413)
                     /locus_tag="ACIZE9_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093701.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(20410..21084)
                     /locus_tag="ACIZE9_001847"
     CDS             complement(20410..21084)
                     /locus_tag="ACIZE9_001847"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGC6093702.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(22137..23435)
                     /gene="asnS"
                     /locus_tag="ACIZE9_001848"
     CDS             complement(22137..23435)
                     /gene="asnS"
                     /locus_tag="ACIZE9_001848"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGC6093703.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(23475..24665)
                     /locus_tag="ACIZE9_001849"
     CDS             complement(23475..24665)
                     /locus_tag="ACIZE9_001849"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGC6093704.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGASENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(24686..25213)
                     /locus_tag="ACIZE9_001850"
     CDS             complement(24686..25213)
                     /locus_tag="ACIZE9_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGC6093705.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(25260..28049)
                     /locus_tag="ACIZE9_001851"
     CDS             complement(25260..28049)
                     /locus_tag="ACIZE9_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HGC6093706.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(28196..28396)
                     /locus_tag="ACIZE9_001852"
     CDS             complement(28196..28396)
                     /locus_tag="ACIZE9_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC6093707.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(28848..29168)
                     /locus_tag="ACIZE9_001853"
     CDS             complement(28848..29168)
                     /locus_tag="ACIZE9_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093708.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
BASE COUNT         8371 a         6098 c         5081 g         9757 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaatagat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatccta aaatataagc
     1201 tatttgttta cttctgtaga atatatactt tgttgttaga taagttgcac atgtttatag
     1261 aatctaaata ataaattttt atgtaccgcc cctcaaagtg aactgaaccc caaaagttga
     1321 actatttaat ggactgtttc cgatattcta ctggagatag tccattaaat agttcaactt
     1381 ttggggttca gttcaaagag ggggggattt tttatcgttg tggaatattt aaataccaac
     1441 gcttgtcatg aaaatcttgt gctccaccct tagtatttcc ttctggatcg tttgtcgcac
     1501 gcatcatgac gtatactttc ttattaggga aatcacgcat attgaaagat acatgatagc
     1561 caacatttcc taaagtatta taagcttgat ttacgtctgg tctataaatc ccatcagctc
     1621 ttactctagc tagttctttt ccagtattgt agtccataat gaaaatatac tcgtatttat
     1681 aattagcaat gtgccatcca gctacatgca agtttgcgtt ttcgatttct ccgaactgat
     1741 caatgtgggc gtaatttgtt ccatctgtca gcgtagaatt tgcagcacct gctcgagttg
     1801 gatcaattac tggtttatcc tccgaagtag ttggattatc atccgtaaaa ccatgagcca
     1861 aatcataggc tagtttttct ttacttacac ccatttcaga aagataaccg taaggatctg
     1921 tatgatcgcc ccaaatattt tgtgttaccc ataaatgcga tttgattcct ggttggttat
     1981 aaggagtgtc taatgttaat ggaataccat atttcattgc tgaatctctt gccaattcaa
     2041 cgtatacttt atagttcttt tcaaaagttt ctttatcatg tgtatgttgt aactcgattt
     2101 gcacaggact tttggctcac gaggttgtcc tactctacat cttgctgata gatatgctga
     2161 aaggaaaaca ccaacattat gttttgcttt ttcagctaga acgagacaag caggaatacc
     2221 tttagaagat atcaaaggtt ttttaggtca taaagatgtt tccactacac aagtctatgc
     2281 ccatatttct cccgaagtga aaaaaagatc aatgaatcaa ctagaaaact atatagaaga
     2341 gcaaataaaa aagcactcaa attgagtgct tttttaagct cactatcact aaaactatca
     2401 ctaattttat ttataagcga acatgtttct atcactgatt ttttaaatct agcgaaaaac
     2461 ccttatctta aaggcgttcg ttcaattctt tggcaaggtc ttcaaagcct ggcttgccta
     2521 gaagtgcgaa catggttttc ttatagctca tgtagaaaaa ttttcttgat gatgatttta
     2581 tccatcaatt gagattgact gttttgctct cctatgattt cagctatgat tgtccgattt
     2641 tgcggttttc ttcttaactg gtagttgatt ttcccagttt ccatcaactc gctaagcata
     2701 tccacgactc cgccaaatcc ggtctttttc gtaataaaac ctagtgctac cattcgttca
     2761 tctagatttt ttgctgtaat cgtcacacca gtaatgagcg agtgctgtaa tgtttgggcc
     2821 agctcttcca tcccttcagc attggatacg acggaagctg ttttgttaat aggttcttcg
     2881 tttatttctt ttggttcttt cctctccact ttcactgttt gacgaaggac atctagttct
     2941 tgcaagagcg tttcgtattg ttcttgggtc agcatcacgc cagctacttt ttcacgatta
     3001 aatatatata cgccagttcc cgcgtctcgc gcttgagcaa atacatccat cggcgatcgt
     3061 ttcacttctg tgatcgaaga tgtgggaact tctaatttct ttaattccaa tggatttcct
     3121 cctttactaa tcgcttttta ttatagcaca gactgacttg ttttgatctt ttttccaaag
     3181 gttttatcgg tttttgccta accagtaatt gatatcggta agaagtcttt cgataccaaa
     3241 tgaaggatgg tacagatacg ttttttgatc ttcgttatgg tctagtggaa aaaaatgatc
     3301 gatgatcact agatctgcat accgaggcgg cttatttcga gtacatacat gtatagagat
     3361 ccgttttcga tgtcttagcg ttttgttcag taccccagca agtcttcttg cttcttggtg
     3421 ttcatagcga aaaaaaaaga cgattttcac ttcaggaggg tggacatcta aataccctcg
     3481 ttcctggagt gttttcagta aaagcatccc ccactctact gcggggtgtg caagtgcttg
     3541 ttggatcgct agccgaaatt gatatagttt atctttggaa ttgggaaatt tttctaatgt
     3601 ttcctgataa taacgaactt cttctatcag ccggtcatgg ataccaatta cgtaacgaag
     3661 tcattcttgg taaagtactt ttgtcagctt tgatttgctt tcgctctcaa attcgctatt
     3721 cagccaaaac agcgaatcaa gcttttcagt cacaatcgtc aatttccgat agtcttgtgt
     3781 ctcttctatc cgtttccacc gcttttcagt aatctggtta cagctcaagc gcaaaattgc
     3841 tagataattt ttttctttta ttggcaaaat ctgctcctct ctaaatagca attcaggaaa
     3901 caattcaaag aatagtgttc gactgtctcc taaaatctcg atttctgccg gatcctttct
     3961 ttgcttcaat aattggatga acatctcaga aaaggactgc tctccatcat ctgcaaaaaa
     4021 atgcggaaaa tctttcaaaa agcaaaacag cagatatctt acttttcttt ctgaaccaaa
     4081 gatctgtgct tttttataag aaaaagaaag gtggtactcg ccaaaccact ttctcaatcg
     4141 ctcttgcgta gaacgatcgt acttctgctc gtaaggttca ttcaatagca gatttttcag
     4201 taaacaaaac gggggtgatt ggatcagaaa aacaaacaag agataaggtt cgctatatcc
     4261 ttgatcataa actaactgaa cggttttctt atgaagaatc agctgaatgg gacagtcgct
     4321 ttccgccaaa cgtttcagat gccgatccac tgttttaaca tcgattttca gttcttcagc
     4381 taaatcagct tttcgccaga tcaaatcttt cattagattg attagtgaaa ataaattctg
     4441 tgcatttttt gataatagtt tttgccatct catcgatcat ttctcacctg atttctaaac
     4501 atattgtttg atcaaaatgg gttcactcct aaaaagataa aaaactccct ttctatttat
     4561 ttaaatacgc aaatcttcct cattattttt tattttactc aatttaatcg tattctcatt
     4621 tcaaaacgaa tgtactttaa aaaaacataa taagatcact ttgcttgtag gatgtattcc
     4681 cttccattac aatgaaataa atagcgattt tatgagaagg tgatgtgaaa atggaagaaa
     4741 aaatagaaga atccaaacaa aaaatcgatc agttgatata agaattagaa aaagcggtca
     4801 tcggcaaacg ttcaactatc caattgatga tcgtggccct attagcaggt ggtcatgtct
     4861 tattcgaaga tattcccggt gtaggtaaaa cgttactggt caaagcacta gcaaaagctg
     4921 tacagggaac cttcagcaga gtccaatgta ctcctgatct gctgcctagt gatattcttg
     4981 gtttttccgt atacaattca caatcaaaag agtttgaatt tcgtccggga ccgatcttta
     5041 ccacgatctt gttagcagat gagatcaatc gtacgactcc tcgtactcag tcagcacttt
     5101 tagaagcaat ggccgagaat catgcaacga tcgacaacaa tacataccct ctagacaatc
     5161 atttttttgt cttagctacg caaaatccaa tcgagtacga aggaacatat cctttgccgg
     5221 aagcacagct cgatcgtttt ttattccgac tacaaatcgg ttatccttct tttgatgacg
     5281 aacttttgct acttttggat aaattcgaaa aagtgttgga taacttaaat gaagtattga
     5341 acagttatga aatagaagaa ataaaaacaa atgtggcgaa tgtctttgtc agtcccgaag
     5401 tggcatctta tgccttgcag ttagtgtcag caacaagaag tcatgctgcc atccagcttg
     5461 gcatcagtcc acgaggaagc ctttccttta ttcaggcagc aaaagcttat gctttaatcc
     5521 atgggagaaa ttacgtcacg cccaaagatt tgcaggattt agttccttac gtgttttccc
     5581 atcgcctgat tttttacgat cgttcattga aggaagacga aaagaaacaa atcattcata
     5641 ctcttgttgc acaaattcct attcctgtga ggtagattga ggtagacaat ggaaaaaatc
     5701 aaagattatt tcattaattt tgtgttattt ctggtatatt tcatcattgt gctttttgct
     5761 cttgtattca acaattcttt aggctggttc ttgttggcct tttttactct ttatgtatca
     5821 tggagcttga tttcattaag cagctttcta aagaaacttt cggttacttg tacattgcag
     5881 ccactcgttt atcgcaaaaa aagtatgcag gttatttttt ccatagcaaa aaagagaact
     5941 ttttctttac ctctccctcg tttacaaatc ggcttcccag caatctttgc agaaaaaaac
     6001 aagagatttt gattcttaca aataaaccgc aagaagtcca attgctttgg cagccaaaag
     6061 aaagaggatg ccatgaaaca ttaactgtca tttttacagc ctatgatagt ctaggacttt
     6121 tcagaaaaag tgcaaaaaga gagatctctt ttcctgtgac tgttctgcct gctttttgta
     6181 agattcaagc agaaaaatta cagagagttc tggaaaaaaa acagcagctg aacgcgtacc
     6241 aaagaggtct tgattttcgg gaacatcgcg cttatcgtcc aggtgattct ttcaaccgaa
     6301 tcgattggaa attgtctgct catactcaag agtggttata ccgtgaatac gattatcaag
     6361 aagaagaatg ttctcctctt ttttgctttt ggggttcgcc cagtccaaaa tttgaacctc
     6421 tgctagactt gtatttttct ttatggcatt tgagaaaaga aaagcagccg gaacttctga
     6481 tattaggcaa ccgcgccttt catggcaaag accccggtca tacctatttt gcttctttgg
     6541 aagctggcga tgagaaagct tttttcgcac acttgaaaaa atatgcaaaa aaacaaatcg
     6601 tcctctttgt tcctgagaat tctcctgaag tctcagaagc tattgaaaca ttgtcaaaag
     6661 atcgaacggt ttatcttgtt tatttcgtag aaaaacaact catggtccaa gaaaaagaca
     6721 agatatgttc attgccagga ggtgaatgga ttgacgatta aacgggaaaa atggctgcgt
     6781 ggcgtttact cctttgtgat actaagtgta ggtgctccga tatttgtagt agctaatcaa
     6841 ttgcaaaaca gctaccttct tatcctaact attggtgtcc tatgccttat tgtctgctgt
     6901 attcctaaaa aatgggtacg tttgctgctt tctttgccag taatgatagg ttgtttgttt
     6961 ttatattttc cttcgaagac attttccata ttatggatct tacagttttt ttcgtcagtc
     7021 acagaggaat tcttccatct atcccaaggt aaactttatt atttgccaga aaagacagct
     7081 ttttttctca taatgttgct gatctattta tttattacat tgaccgtgga ttacgactat
     7141 tggtacgcac cctttctttc tttgatggct tacttcatga tgcttaccgt ttttcggaaa
     7201 aaagatttac tgtacgaaat gattgcggta gtaactgttt tgttcgtgta tctggcagca
     7261 aggcaatttt tctccatccg gttgttgtcg ggaaacactc gattccagtc attgactaca
     7321 gttctgctta tttgtttctt aacttttagc gctatcttgc ctttatatct tccgaaagta
     7381 caccaatctc tcgaggaaac gagtgaaccg atccgagaat atcttaatga tgaagggctt
     7441 tatgacacac tccatgagta tcaattaacc ggaagtgcaa gaacaggctt cagtgagaat
     7501 gatgaacagc ttggtggacc tttatatgat aatggcgaag ttgtttttac agcgaaccaa
     7561 aaaggaaatg gctattggaa gatcgaaaat aaaaatcatt acaccggttc tggatggata
     7621 gaagatcagg acgcacccat ccaaccaatc caagaattcc ctgttgacat cacgagctac
     7681 caaaccgtta tagaagacaa agaaaacatt acattgaccc taaaaaaaca agttttctta
     7741 ccttatcctt atggaaatac taccttgact gatttttcat tagctagtgg acaaacgctt
     7801 tactatttgc ctgaaagcca gcgattcatt cctgtcccga atgaatcgac acgttctgca
     7861 actttacaaa cagaaaggtt agtttttacg agagaagaat taaaaagcag tcagttaaaa
     7921 gctgatgatt tagaaaatca gcagacaaat cttcaattgc caaaaagttt gcctaaacgt
     7981 attgaggact tggcggtcga attgaccaaa aatgaagcaa ctttaattcg taaagtcgaa
     8041 gctgtctaac agtatttaaa aacaagcgga aatttccgct attccaaaac ggataccggg
     8101 catactccaa aagaacacga ttatgtggat tatttcctct ttgattcaaa agtcggctat
     8161 tgtgacaact tttcaacttc tatggtcgtc cttcttcgaa cacttggtat cccagctcgc
     8221 tggacaaaag gttttacaaa tgggctcaga acaggcacag ataatcaagg gaatgaggaa
     8281 tacagcattc tcaatagtca tgctcattct tggccagagg tatactttcc tggatttggc
     8341 tggcttccat ttgaaccaac cccttcattt gccaatccaa tgggttcaca accagttgct
     8401 gaaacaaccg aaaccgtcca gcctgctatc gaacaaccaa atgaaagcga aaatatggca
     8461 gaaactattt ccagtgagag atctgaggtc attccatcag aagaaacaac actcacacca
     8521 gcttataaaa tcgtcttatt cagccttgga gtgtgtttat ccgtcttgtt gttctttcta
     8581 ttgttattca gaaaatctct gcgctggaca agttatctta tctatcttca tttttttgct
     8641 tctactaata cgattgcata tcaaaaactt cttaaccctt tggaaacatt ggtaccgcgc
     8701 aaacccgcag aatctttgca ggaatatagc ctgcgaatag aacaagaatt caagctagat
     8761 ctgcgtttca ttcgattaac tactcaatat gaagcagaaa tatatggacg acaagcagat
     8821 ccggtaaaat tcgataaaaa aacctattta gaaataacgc atataataag aaaaatggta
     8881 tacaaaaaaa ttctgacaaa agggagccgc ttcaaaaaat aagataaaat ttctggagaa
     8941 tctacttctg gaatgccgag aaccagctga ttgagtatcg attactcgaa aaaaaggttg
     9001 tgacacgttt tttgtcacaa ccttttttca ttattatctg attttcaatg tcaaagcatt
     9061 tagagctaca actaccgtac ttaacgacat caagacagca ccaactgctg gacttaatat
     9121 gataccaatt ggcgcaagaa ttccggctgc tagcggaatt gcaagaatat tgtaacctgc
     9181 cccccaccag aggttctgga tcattttctt tcgcgtttgc ttggctagat caagaaaatg
     9241 caaaatatct tttggatcgc tgtttgtcaa tacgacatcc gcagaatcga ttgcgatatc
     9301 tgtccctgca ccgattgcca tcccgattga agcacgggct aaacttggcg catcattgat
     9361 cccatcaccc accatgatta cttttttccc ttggtcaagg tatttctgga caacagcttc
     9421 tttatcatct ggtaataaac cgccataata ttcttcgatc cctaaataat ctgctactgc
     9481 ttgggcagcg tttttattgt caccagtaag catgacagga gtgatttttc tttctttcaa
     9541 tgttcggata aattcttttg cttctgtttt tactacgtca cctaaagcaa cgattgcagc
     9601 tagatgattt tctaaaatca ggaagctgat ggtatttcct tgttcttggt aaggtttcaa
     9661 taatgcttgt tctacgttta atccgagacg ctcaacttct ttttcattaa ctattttcac
     9721 ttgttgtttt ttgactgttg cctctagccc gactcctgaa agatttttta gattttcagc
     9781 ttgataaggc ttgatttcat gttctttcaa ataattcata atgccaacag ccaatggatg
     9841 attggcattc gcttccaagg ctcctagata ttgaaggatt tcatttttat tgaacgcatc
     9901 atcaagtact tcgacacccg ttacagtaaa ttttccttct gttagtgttc ctgttttgtc
     9961 cagcatgatc acatctagat cattggcttg ctccagtgca ttgcggtttt tcaaaagtaa
    10021 tccgttttta gctgctattg atgtggaacg agcaacaact aatgggatag ctaaacctag
    10081 agcatgagga caggcgatga taaagactgt taccatacgt tctaatgcat taggaagatc
    10141 tgtcaagaac aaccaggcga tgaatgccag gatacccaca attaatgcga cataaaacag
    10201 ccattttgcc actttgtcag ataatgactc tagcttggat ttttctcctt gtgcttttcg
    10261 caccatttcc ataaccttcg ctagataacc attttcacca gttccagtta cttcgatttc
    10321 gatcgttcca tccccattga tagaaccgcc aatcactttg tcattggctt gttttttgat
    10381 tcctcttgat tcgccagtca cagctgattc gtcaacaatt gtttcacctt tcaagattac
    10441 accatctgtt ggcattttat caccagaccg gacgatcaaa cgatcacctt cgtttacttc
    10501 tttcaatgaa actgtctctt cttttccatc tttcgtcaag cgtttcactg attctggcag
    10561 taattctgct agtttttgta aagcattgct ggcattcgac acagcattca tttcaatcca
    10621 gtgacctagt agcataataa cgatcaaagt agccaattcc cagaagaaat ccatgacgtg
    10681 tgtatgtgga ttgagcagat ttgcgataaa cgaatagaca ctataaatat atgcaactgt
    10741 aatccccatc gcgatcagtg tcatcatagc aggacttttt tgtttcaatt ccatcttagc
    10801 tccacttaaa aatggctgac cgccatagat aaatagtata gttgctaaga tcaatacgag
    10861 ccaatcagaa ccaggaaacg ttacttgaaa tggaaattcc attcccatca ttggtgaaaa
    10921 aagaatgatt gggatagcta ggataagcga tagccaaaat ttttgtttga aattccccat
    10981 gtgcatggaa tgatccatgc cgccgtgttc gtgatccatg tgcatcgaat ggtccatttg
    11041 tttgctgttt gctatatctc catggttatg tcccatgtgc atggaatgat ccatctgact
    11101 atggtcatgt ttcatctcca tctgtttttc atgagattct gtactttctt tgtttactac
    11161 ttctttttta tgctcatgtt ttttctccat atcgttccca ttcattttta ctccatccct
    11221 tctcttactt tttcatgtgt cgatttaagc acagggagtt caacaataca ctgacggaac
    11281 taaacgccat cgctcctcct gcaatgattg gattcaaaaa gcctagtgcg gcaaaaggaa
    11341 taccaatcgt attatagaca aaagcccaga aaagattttg tttgattttt ctcaatgtca
    11401 acctagacaa ctcgattgtt tgtgcaatgg atgccaaact gctattcatc agcgtcacat
    11461 cggctgtttc catcgcaatg tccgttccac ttcccattgc cataccgaca tcagctaatg
    11521 ctaaggccgg tgcatcattg attccatcgc ctgccatacc gacttttttg ccatctttct
    11581 gaagtttttc tacgtaggct gctttatcct ctggaagtac ttcagcaaag atatgctttg
    11641 gatcaatacc aacttgttta ccaatcgttt cggctgccag tttgttgtct cctgtcagca
    11701 taaaaacatc taatccttta ttctggagct gcttgattgc ttgtttgact tctagtttga
    11761 tttgatcagc cacggcaatc aacccgatca cttgcttttc atcagctaaa aacatgactg
    11821 tttttccctg ctgttctaat tctaacgcgt gttcttggta ttcatcaaat gataggttca
    11881 attcaattaa tcgtttacgt gtacccgcaa aatagcgtac tccgttaatc gtaccgctga
    11941 ttccagcacc tgggtgggct gtaaaatcaa tcatatcgta tgttgctgct tcttgcagtt
    12001 ttccgtattc cacgattgct ttacctagtg gatgttcaga agcttgttct aaagtataaa
    12061 aaatagatag gacttcttta gaaccgacta gatctgtaac tttgggcttt ccttctgtaa
    12121 tcgttccagt tttatccaaa acaatgctgt ctaagtgagc agctgcttct aatgcttctc
    12181 cgcctttaat taaaattcca tttcgtgcac caacacccgt tcctaccata atagctgttg
    12241 gagtcgctaa acctaatgca catggacacg caatgactaa tacagagaca ctatggatca
    12301 atgcgagttg ccaatcacca gtgatcaaac ctgtagctat gagcgtgata aacgcgatga
    12361 ctaatacgat cggaacaaaa atccctgaga tccgatctgc gattttttgg attggggctt
    12421 tgctcccttg agcatcttcc accatttgaa tgatttgcgc taatactgtc tgcttgccga
    12481 cttgtgtaac ttccatgtga agtagaccat tcgtattgat tgtcccgcca aagagcgtgt
    12541 catccggatt cttttctaca ggaagatttt caccagtaag catactttca tctatcgcac
    12601 tgcttcctga aataattcga ccatctgctg gaatctgctc accaggacgg atgactagtt
    12661 gatcaccaac gactacttct tcaatcgcta acgtttcttc tttcccgttt cttatcactt
    12721 gggcggtttt tgtttgaaga gacatcaatt gtttgattgc attacctgtt ttcgtttttg
    12781 ctgtatgttc caaatatttg ccgagcaaaa tcagcgtgat gatcatactg ctgctttcaa
    12841 aataaagatc ttgggggtgt ccacggaaaa atccgttgta aatgctcaat gcaaaggcag
    12901 ccgatgttcc aattgctacc aatacatcca tatttggtgc tttcgtcttg attgcatggt
    12961 acgcaccttt ataaaaacga gcaccgacat aaaattggac aggagcagac agcactaact
    13021 ggacgattgg aaaatgaaaa aagtgaacaa tcgccgcatg gcttcctaac atcatagcaa
    13081 tcattgacaa catcaacggc aaagtcaaaa ccgtactcaa tataagatcg aatagcattt
    13141 ttttcaaata cgcttgcttt tcttctgcaa ttttttgttt gtgggcttca tcgtacaaaa
    13201 ttgcaccata gccgatgttt tctacgcttt ggattaattt ttcagtggtc gtcccttcat
    13261 atttgacact tgctttttca gtggccaagt tgactgtggc attgaccaca ccaggttgtc
    13321 cgttcagctc tttttcgatc ctagcagaac aatttgcaca agtcatacct gtaatgacga
    13381 acgtatccat tttggtttct gctgttgcca tcaaatcacc tctgctttat aacccaatcc
    13441 attgattgct tgacaaatct tttcggattg aacttttgtt tcatcaaact tgaccgtacc
    13501 gtttgctttt ttcaaattta ctttcacttt ttgcacgccg tcaagtgcgc ttactgtttc
    13561 ttctactctt gctgcacaat gattgcagct cataccttcg attgaaaatt gttgtttcat
    13621 tttttcttcc tcctattgat gttgtttaca ttcacattga cctgggatac agttacattc
    13681 gatcgtatct actggttgct tttgttccag ttgtttcaaa atctcattga tatcttcttg
    13741 agtcaaagtg gcttcttcta ctagatccgc aatcgtctct ccaatccttt ttgcacagat
    13801 atgggaaaaa agattttccg tcgcactgcg aactgtttcc atctccgaga cagctggatg
    13861 ataaatgaat ttttttcctt cttgttctgt ccagatcact tcttttttta ccaaacgtcc
    13921 cagcaaagtt ttgatcgttg ctggtttcca atccatcgaa tcagctaaga tctgcgtgat
    13981 ttcttgggct gtcgtctgtc caagtgtcca aataacacgc atgatctccc actctgaatc
    14041 actgatcttt actggcgttt tgactttttc catttatttc acacctttcg tttacaaatg
    14101 taatcattag cttatgaata cagattacgc ttgtaaacaa aaactgtcaa ttatttttgc
    14161 tctctatttt caatttagtt aaaaattctt gtttctctcg tcttgtttta aggatgatca
    14221 gtttatttct tgcattagct acttggatca gctgctgtat tttcggttca ttgttttctt
    14281 caaaatgcca gataaaagat aaaaattcta agtattccct gtttagtttc tctgaaaatg
    14341 attcaggcat atctggccga gattttttgt ttatctttct ttttagagaa cgccaaacta
    14401 ctcggtagat ggcgagataa cgcggcactt taagccaaat gatcttatct gcttctttaa
    14461 tcctttcctc taatgtagaa gtataatttc cttcaacaat ccatgacgga ttagatacca
    14521 taaacgattg ctgttcttgc aaaaaccact tttttgcctg aatactgtag tctgttgtat
    14581 gccataaaag gtctagcggc agtagcggaa agtcggtgat ttctttgatc ttccttgcga
    14641 gggtcgattt tcccgaccca ctttgtccaa tcacgatgat cttcattctt ctccctcact
    14701 tctctttgga atttggttcg atcataccac ttataacgcc gcaaaaaaac aagggactgt
    14761 gacaaaagtc gtgtcaaagt cccttgtttc gaataaatgg tgttcaatca gctgaccttc
    14821 agcattaact caaaaaacgg caaaatatga ggagctattt tttcgtttgt tcctctaata
    14881 ctcaggtcaa atcgctgatt ttacaacctc ttccttaaac ggtgttctcc tgccaacacc
    14941 tcggtcacaa ggcacaatag tcaacaaaca tgagaagttg ttttttgaaa ttgctccttg
    15001 tgactcggag ttaaacggca ggctcactac ctctttctta aacggtgttc aaaagcttgc
    15061 atctgcggta ataagcccag caaaacgaaa aatatgaggg gctatttttg tttggctgtt
    15121 cttattactt gatgcaggac agctttttca caacctctga ttcacggtgt tccagaagta
    15181 gcttctgcga aaaacaagcc gaaacttcac aaaaatttga gaagcaattt tcgtaaattc
    15241 cttcttattt cttgaagctg accacttctg tcacaacctc ttgtaacaag tatttctatt
    15301 ttaaggctga accactgttt ctggttcagt gatttctttg tttttgtctc gacgagcaat
    15361 tgctggcaag atcataccta ataagatcaa gacaattggt gtgatgatat tcgtgaataa
    15421 ttggaaccac catgctttag gatcagcagt ataatctact tttggcacca ttcctaggat
    15481 acatgcaaac gcagtgaagg caaagcacca agcaccaaag ataaaaccga tttttggatt
    15541 tttaacaaat ttatattcag aattgaattt cttataagct ttattcaaca tcatatatgc
    15601 caagaacacc cataggtaac gcattggcat gacaactgag ttcaagttcg tcaaccattt
    15661 tactaattca ttcatatctt tgataccaaa gatcggcaac aaaataatga ttcctactag
    15721 tatacctgtc agaagataac cattcaccaa tgtaccttta cgattacgtt tacgtagcca
    15781 gtttggtaca aattctggat ccgcatctgc taacaagatt tttagtggtg catcaattga
    15841 aaaggctaat gcggagattt gtccaatcat gtttgtcaat gcgtaaatga tcatcaatga
    15901 gttaccgata ccatagtaat tacctaaaat ttgaaaagca ctgtatgccc catttgccat
    15961 caagtcttta ggaatattat cgctagcaaa cagcataccc attgcgactg agcctaatac
    16021 agcacaaatc cctaccattg ctgctaagaa gatcatccct ttaggaaatt cctttgcagg
    16081 atttcttgta gagttgacat aaggggatat tttttccgct cctccaactg caaatactag
    16141 catcgaaacg gttgtgaaat aactgaaatc aaatgttgga atatatgttt tcacttgatt
    16201 catatgtggt gtggcaaatt ccatcgttgg attgatgaac ggtgccgtta cagctaaaag
    16261 aataaataag atcgacatga cgaacatcgc tgttccggcc agtccgccaa tcactttcaa
    16321 agtagaaagt ccttttgttg ataaatataa aaaggcaaga aatataataa gtgaaataac
    16381 tgctaccatt tgtactgaca tcgtatttac gatatttcca tttccttgga ctgcccaacc
    16441 gccagcaatc aggattgctt gaggcttttg tgccaaataa ggaatatgga cgacccagta
    16501 agtccaagcg gcatagtatg ccagtcgttt attagatgtc gtattttcga cccatgaact
    16561 gacgcctcct ttactatcct tgaaggctga ccctaattgt ccaacgatca atgcgtatgg
    16621 aataaaataa atggccaaaa tcaatagcca agaggtgaca actgatactc cttgctgagc
    16681 atagttatta actacattcc ccatgcccca aaccatgtta aatgcaatta acgcaacagt
    16741 aaaccagcgt aattgtttgt tgttcattcg ttctctcctt tatgataaaa atttgttatc
    16801 cagatgtaat catattcaat ttttaacaaa cttacaagac agtgttattt tatgtgtgta
    16861 ttcttttatt taatacacat cgttttttca tattttttcc atcaaaaaaa taagttattt
    16921 tcttttattt catttacctt attgaatttc aagctatttt gaattttctg caaaattaaa
    16981 aacattagtt attttataat cctatctatt ttctttacat ttttcattaa gaaaaggata
    17041 taaaaaaaag aggacgttca ttcgtcctct tcattgatca acgtttattt tttacatgca
    17101 agcttcgcat ggcattcaaa acagctaata ctgtcacccc aacatctgca aatactgcat
    17161 ctcccattga tgcaaaacca aaagcaccta aggcaagtac caaaattttt atcccaatag
    17221 caaagacaat gttctgtttg acgattttca atgttttctt tgctaaatgg attgcttctg
    17281 caatcttcga tggttgatca ttcatgatga ctacatctgc tgcttcaatt gcagcatcgc
    17341 ttcccaatcc acccattgcg attcctacat ctgctcttgc tagcaccggt gcatcgttga
    17401 ttccatctcc gacaaatgcg gtctttttat tgtttctttg taagatttcc tctaaccgct
    17461 gcactttatc ttctggaagc aattcgctat atatcttgtc cacgcctact tgcttcccga
    17521 tatgatcagc aatttttttc gaatcgcccg tcaacatgac tgtgttcttc acaccagcct
    17581 tttttaattg aaccaatgcg tctacggcat cttctttcaa ggtatctgca ataacaagat
    17641 aaccactgta actttgatcg atcgctagat aaagcaatgt accgatttct tgacttgaag
    17701 gaaaagagat ttcaaatctt tccatcaatt tgtgattacc tgctaatact tgtttgccat
    17761 caacttcagc taagatccct tcacctgcaa attcttggat attagctgtt ggtaaaagcg
    17821 gacctgcgta gccttctaaa acagattgag caatcggatg tgtagaaaac tgttctgcac
    17881 tcgcaacata ttgcatgaat atctttggat cgatttttgt atcgatcgtc tggatcgaaa
    17941 agtcaccttt cgttaatgtg ccggttttat cgaataccac tgtctcagtt tgtgcaagca
    18001 actccaagta atttgaacct tttactaata caccgatttt acttgctcct ccgataccgc
    18061 caaagaaact aaggggtacg gagatcacta atgcacatgg acatgagatc actaaaaatg
    18121 tcaatgctcg atagatccat tcagaaaacg ccgctccaga aacaacaagt ggaggtaaaa
    18181 cagctaataa aacggccaat cctacaacga ctggtgtgta atagcgcgcg aatttagtaa
    18241 tgaaattttc agctggtgct tttttactgc tggcattttc tactaattct aataatttgc
    18301 tgatagtaga attttcataa gatttttcta cttgaactaa aaatggttta tttttattga
    18361 taaatccact taatactgtt tcaccaacat atacagattt agggactgat tctcctgtaa
    18421 gtgctgacgt atcgactaat gattctcctt cgatgatcgt tccatctaac ggtacacgtt
    18481 caccaggctt cacaagtaca aactgaccga tctgcacgtc ttcagggttc acggtcatca
    18541 atccttccgt cgtctgcacg tgagctgttt ctggacggat cgccatcaat tcgcgaatcg
    18601 attttcttga atgactgact gccaatcctt ggaaatactc gccgatttga taaaatagca
    18661 tcactgctac ggcttctgga tattcaccga tcaacatagc gccaatcgta gcaacagaca
    18721 taagaaaatt ctcatcaaag atttttcctt tgacgatatt catcactgcc ttcttcacta
    18781 catcatatcc tatcagcaga taaatcaata aataccctat caagcgaatt ggttcattaa
    18841 aatcaaataa tagcaataaa gcgatacctg caagggaaaa taaaatccgg aacagcgtat
    18901 ttctctcttt ttcatttcca tgttcagata ctttttcctt atctatttct gttactttga
    18961 catctggttc taattccttc actacttttt ttatttcttg ttcaatcgta gccaaatgat
    19021 cttcctctgc gtcaatcgtt agttttccag aagtgaagtt taccgttgct tccttgactc
    19081 cattgatctt ctgaactcct ttttcgattt tcattgcaca gttcgcacaa tctaaacctt
    19141 ctaatctgta acttttcatt ttaatgacct cctcgcctca acatatgaat atctcttcat
    19201 aactaattat aaatgaacgg ttattcatat gtcaaggtat ccgaaagaaa aaatgaaaaa
    19261 catctgcatc ggaaaatttc ttccatacag atgttttggc ttattctttc tttttctttt
    19321 cgatcattgc cactgctctt atccaacccg cacttgcctt cttgatcttg acaggatagc
    19381 aactaagttt gaagcctgtt gctggcaatt tgtctaaatt cattaatttt tcgataggac
    19441 aatatctttt ttcaatccct gcaaaatgtc cttcccagat attcgaagct ccactacgct
    19501 ttcaaaaata tagaaagagt tctttaatga aaattatttc aactttccat aaacagtaac
    19561 cccatataaa taaaagacgt aaaagtcaca tggaagaact tatacaggag aacgcataga
    19621 gtcaggtgaa atacatgtat cccacctgac tctatgcttt atctaacctt tattattctc
    19681 ttttatacaa tttctgcacc gaatggcatc aacgccaatc gagcaagttt gaaagattgc
    19741 ttggcaaaag gtatccctat gatcgtgata catagaagga tgccgctgac gacatgtgcg
    19801 agagcaattg gtaggcctga aacgatcagc cagatgatat taacaatcaa tgacatgcca
    19861 gactggtgat aaattacttc tttgccaaaa ggcgcaaaag aaagggaggc gatcttaaaa
    19921 cattgcatac cgattgggat acctatgatc gtgatacacc aaagtatccc cgctgctaac
    19981 cagctaagac caccgattag tccgccgaat ataaaccaga tgacatttcc taaacaactc
    20041 attgtatttc tccttctatt actgtttttg attaaaactg ggcaaaaaat gattttattc
    20101 ttcttttttt agcttccagt atcaaatatt ctgcaaattt tttttggatt tcttccgtat
    20161 tttcttttgt tactaatgtg tgttggatta gttttcctga tggtcgctga tccaatcgtt
    20221 cttctgactg ttgcacgtcc gcttgcgcaa atccgataat ccgtttttct tttgttacag
    20281 caacgagcaa tagtttattc ttatcattta ggtcagctgc cgtttttgct tttacgaatg
    20341 attctggatg atcagtaatc agctgattga tttgaggtag atcttctttt actgcccacc
    20401 gtatttccat catttctcac ttttctttcg ctcattttta tctccactaa aaaaatcgac
    20461 tgcggcaatt gcatctatcc agctttgtgc aatgatctca tgtccgccaa tcgttgggtg
    20521 gaccccatct tctcttgtat atttcgaaaa accataaaca atccctaaag cattgaatat
    20581 accatctaaa ggaaccagca atgcgccata ttccttagca agtttacgaa caatttggat
    20641 tttagggtct aagtctttac gccagccatg acggtcgtcg gttataggaa gtacaaacgg
    20701 ctccatcaag atgatgttgc agattcccac tgtttgaagt tcatttagta attttcgata
    20761 aacggattca aattgctgag cagatttctc agttccgaat atagcctgat cgctagtatt
    20821 atgccaggta tcattgattc cgatcaaaat cgatacatag tcaggttgta aagctaaaca
    20881 atcttcttgc cagcgtactt gcagatctgc aattttgtct cctcctatcc cacggttcat
    20941 gcattcaaat tccatcgttg gatattggga gattagtttt ccggcaatca aaagtggata
    21001 acctttacct agatcagttg cttctgctcg gtctcttcct gcgtctgtaa tgctatcacc
    21061 gataaataat atacgttttt tcatttgtca aaaactcctt tttgaataaa acgatgattt
    21121 tcttccttat attatcccat aagccctatc aagacgaaag agaaaatata tgtataaaaa
    21181 atgacaccag cctagtccct tcaaacaatt gaatgaacgc tcatcaagtg tctagttttt
    21241 tatgctattt ttttcttaac gtgccggatt ccccttgatt ccttcgttgt ttggtccaga
    21301 gagatcgatc acacctaagc ttccgtcaat cagaccactg atgacgccat cagaacatat
    21361 atttataggc tcatctaaga cttctagtaa atgtcccttt actaatatct cttctagatt
    21421 gcttgggata gattggtcat aactttatct ggtccgatga tttcaagggt gaattgaact
    21481 tacatatgga ttattgcatg ctgaaaatac ggacctactc catcttcgaa tgttactatt
    21541 agtttgtttt caggtgctag atgctgcttt atttcaacag cagaagcatc atcaaatcag
    21601 atttccattt gaattacctt ctttgtaaat gtttgattga ttgcgatttc gttatagaac
    21661 cttgtgaatc aaatagcaat ttcttttgct ttcttctctt gtctgctgga aacttccttt
    21721 atcccgtatt ttaaaaaaag aactgcgaga gttcgcagtt cttttttaga ataaacggtg
    21781 ctctccggcc aactcctcgg tcacaagtca caatagtcat caaacatgaa aaactgtttt
    21841 ttgaaattac tccttgtgac tcggagctga acggcaggcg cacaacctct tccttaaacg
    21901 gtgttcaaaa gccagtttct cggtattaag ccaaatttat gcaaaaatgt ggaaagccat
    21961 ttccacaaaa tttttcttaa tactcgaaac taaacagctt tttcacaacc tctccactaa
    22021 acggtattca aaagcttaca tctgcggtaa taagtcccgc caattcaaaa acatgaacag
    22081 ctgtttttgc ttggctgttc taattacttg atgcagaaca gctttttcat cacctcttat
    22141 ggataaattc ggttcaacaa acgtgggaat ggaatagctt cacgtacatg gtcgatacca
    22201 gcaatccaag tgactgttcg ttcaagacct agaccaaaac cagagtgcgg aacagaaccg
    22261 tatttacgta gatcaagata ccatgaatat tctttttcat ccaaaccgtg attacggatt
    22321 tgttctagca agaaatcata gtctgttgcc cgttcgcttc cgccaataat ttcaccgtaa
    22381 ccttctggtg cgatcatatc tgcacagatc accacgtctt ctcttgttgg atgtggtttc
    22441 atgtagaatg gcttgatggc ttttggatag tttaggataa agacaggctg ttcgaatgaa
    22501 ttcgcaatga acgtttcatg aggtgaacca aagtcttcgc cccattcgat gtcatcaaat
    22561 ccatttttct tcagtaattc gatcgcatca tcataagtaa tacgagggaa tggcaatttt
    22621 gtataagttt ttaagacttc tttgtctcgt cctagtacat ctaatgcata ttcgcaatga
    22681 tctaaaacat tttgtactaa gaatgctaca tattgttcct gtacttctaa actttcttct
    22741 tgatgagtga aagccatttc tggttcgatc atccagaatt cgatcaaatg acgtcgtgtt
    22801 tttgattttt cagcacggaa agtcggaccg aatgaaaaga cttttccgaa agccatagca
    22861 gcagcttcca tgtataattg gccactttga gataaataag ctttttgatc aaagtaattt
    22921 gtttcgaata gatccgtagt gccttctggt gcagaaccag tcaagatcgg cggatcaatt
    22981 ttgacaaaat gatgttgatt aaagaattca tacgttgcac gaatgatttc atttctgatc
    23041 tgcataatcg catgttgtct tgaagaacgc agccataaat gacgatgatc catcaagaag
    23101 tctgttccgt gttcttttgg tgtgatcgga taatcgtggc tctcgcttac cacttccaca
    23161 tttgtaattc cgatttcata accaaatttt gaacgactgt cttcacggat ttctccagtt
    23221 actaacacgg atgtttcttg gtgtagattt ttagctgttt ggaaaacttc ttccgacact
    23281 tcgcttttta caactacacc ttggaaaaag gctgttccgt ctcttaattg taaaaatgcg
    23341 atttttccgc ttgatcgctt atttgcgacc caagcgccga ttgttactgt ttctcccaca
    23401 tggtttttcg aatcgatgat ttgaatttgt tccacgtatg actctccttt tatattcctt
    23461 gaatttcttt aggattaatt ttgactttta ctctcaataa attgcttgat tctgcgtacc
    23521 gcttcttcta acgtagcgcg atcagtagca taactcatgc ggacattttc tgatgcccca
    23581 aagccttcgc cagtcacaag cgctacccct gtttcttcta aaagatcttc tacccattgt
    23641 gtgacatttt catatttaca catgcgtagc gtttctttta cattaggaaa aagataaaaa
    23701 gctccttgtg gcttttcaag agaaacaccc ggcagttctg ccacaagcga atataacgta
    23761 ttcaggcgtt cttcaaaggc gttccgcatt tcttccactg tatcttgctc gcctttcaat
    23821 gcttcaacag ctgcatattg actgactgct gtcggattac tggttgactg ggaagcaaca
    23881 gcgatcattc cattgatgat cacaggattt cccaccgcat aaccaatgcg ccagcctgtc
    23941 atcgcatatg ttttagacac gccgttgatg atgatagtct gatttttgat tgcttctgaa
    24001 atcgttgcaa ttggagtaaa ctcattgcca ttataaacta aacgaccata aatatcatca
    24061 gcaactatca aaatatcatt ttttactgcc cattcaccga ttgcctgcag ttcattcttg
    24121 ctataaatca ttccagtcgg attcgatgga gaattgatga ttacggcttt tgttttttct
    24181 gaacgtgctt gttctagctg ttcaacagta actttccagc tattggattc ttcccctttc
    24241 acaaagacag gaagtccttc tgccagtttt acttgctcac cgtaactgac ccagtaaggc
    24301 acaggaatga tgacttcatc ttgcgggtca aggatcgttt ggaaaagggt atacaaagca
    24361 aatttcgctc cgtctgttac gactgtttgt gaaggttcat agacaagtcc atagtttttc
    24421 ttcagataat caacgattgc ctgtcgaagc tctgggattc ctgctgttgg tgtataatag
    24481 ctagctttcc cgttgcggat tgcttcgatt gctgcttctt ggatgttttc tggtgtcgca
    24541 aaatccggtt ctcccacagt caaactcagc acatctctgc cttttgcttt taatgccttg
    24601 gcctttgccg cagctgccaa agtgacagac ggttctaatc gttttgttct ttttgataac
    24661 tccatcccat tcattccttt accttttaaa ttcccttgat tgtcttgact tcatctccag
    24721 attcaaagcc aatcaggtaa taattcagtt tcccatttgt ttcttttcct actacttccc
    24781 acacaggctg atcatcatac atccctaaag cagctttttc gatttggatt tcaggatggg
    24841 ccgcagcaat tgtctgtttt gcttcgtttt cagtcagtcc ctttgtttga tccaatactt
    24901 ttactttttc accagattta ggaatgataa cggcgatttc ttttccttta tcatttgtac
    24961 ctgtcagtga aaagtatgtc ttctttcgag taaaccaata aaaatgatcg gcttcctcaa
    25021 gatttgcata tttctttgcg atttctactg cttctttctt cgcctgcacc gccggacgac
    25081 tggaacgcaa gtaaaaaatc gagctgatca cgatgaccgc taataaaaat acgatcaagc
    25141 caagtaacac gcgattaatc gttttttcct ttgtctgttt tttcttcaag ggtcgtcgct
    25201 cctttatctt cattcctttt cattatagca gattttaatt atgaaaaaag acagctcctc
    25261 taacttcctt cttcattttt ctttaagaat tcatggatgt cctgatagat ttcctccata
    25321 gctagctctt tgatcggtac ttttttcggt aatgcatgga tgatccgtgc accatatttt
    25381 gcagtgacta gtcttcgatc caaaataagc aatacgccac gatctgtctc cgtccttatc
    25441 aagcgaccta atgcttggcg taacttcaaa gctgctttag gtacggattc ctggtaaaaa
    25501 ggattgatcc cctctgattc taaataagcg ttcctagctt tgaccatcgg gcgaagcgga
    25561 ttatcgaagg gtaaacgtgt gactacaacg atctgcaaag catccccagg caaatctaca
    25621 ccttcccaaa agctgtcagc gccaaacaat acgctttttt ctgacaaaat gaagcgtttc
    25681 aaaagcttct cccggcttcc gccaaaccct tgagctagta tttctcgtcc tttttctagc
    25741 atagacagat gcattttctg atagaccttc tgcaaaacat catgagaagt gaataacaca
    25801 agtattggcc gatcttcttg ttcgatcaga cctgtaagtg ctgtctctaa ataatcgata
    25861 tatgcttgat tgctgacttg atggacggca ggtgcctctt ttggcacata gatccttgcc
    25921 tgtttctcat aatcataagg agaggcaatc actttaagag gtgctgcttc aatgccaagc
    25981 cgcttagaga gatagtgtcg attagggccg atcttcagcg ttcctccaat ataaagaata
    26041 cgatcatatc gaggatacca aacagtcgac ggcaacatag ccgcttgaaa atcatggaga
    26101 tgaaaaatca tctgctgcgc tgtgttccca ggaacgaacc aatggatcaa atgatctcgc
    26161 cagtcttcca gccattgatc catcagcaag tactgcttgt ctaattgatc aaataagcta
    26221 tataaacttg ctaaatcgat ccgcatctgg tttgtccagc tttcttggat aatctcaaaa
    26281 gtcagacgca tttgtgactg tagctgctgg atctcctgat aaaaaagctg caggtgatca
    26341 atggctgtcc cagattccag tggcagctga tccaacatct cttttgtcat catgacttct
    26401 tctggatact gtccgttagg ttgcttgccg ctcactaaac tcattaatcc ttctgccata
    26461 caaatctgtg cttcgcatag cgcagaaagt tcttctcgat aaatcgataa ccagcgtaag
    26521 gcttcatgtt ctttcggtaa atagctttgt attcggtcaa acagctgatt tggttcttct
    26581 aattgctgga tttgtttatg gaaatagtta atacttaatc gtttgtcatt tactttttca
    26641 gcgatttccg gcaaatgatg tacttcatcg atcaacaaaa atggactagc tggaagcaat
    26701 ggttcttttc gctgtgtttc ttgtattaaa aacgcatgat tgacaatcaa aaaattactt
    26761 tgcctgattt tcttttgcaa gaaacgaaca aagtcttgtt cgtaaaatga ctgatttctt
    26821 gctaaaaatc caatacctct gtgcgcgata tctgcaaaga atgaatggtt caaatttgtt
    26881 aaatgtaatt catccaaatc accggtcttc gtttgcgtca gccaaactaa gaccgccatt
    26941 tgatacaaag catattgttt ttgttctggc ggttccacaa gtgtgccttt aaaacgctgt
    27001 aaatcaatat agtggcgata gcttttgata attacaggtt gtatgggctg atctagcaat
    27061 tgattcagca atggaatgtc tttttctatg atctgctgct gcaaaactag cgaaacggta
    27121 ctgatgacag cgggtttttc aggtgtagcc aaataactca atggcagcag ataaccgatt
    27181 gttttaccca ttcctgtagc tgcttcgatc atcaaatctt ttgattcatc ttttgtgaaa
    27241 tggtcgtaga ccgcattcat cagtctgttc tgttcttttc gatacatcag tgttttacca
    27301 aacatttttt cttttgcttg tttttttctt ggatatgtcc gctcgccata atggacggat
    27361 gtgaatagtt ccacttcttt tttctgcaaa gctagcccat cgacgatttc taatgaggga
    27421 tcaagtggct ctggtttttc tttcatttct tcaatcacat gataaatgaa acgactcgta
    27481 tccatacctg tgtgtctact taatcgcgca atctgctcta acgtgatgat tggcaatttt
    27541 ctcatccgtt cttcgatcag caaaagaagt tgacccgtca cttcggcatc actatctgcc
    27601 tgatgaggat tctcatgaat aaatccaagg ctttctgaca aatcagctaa gcgaaagctt
    27661 ggttccgtcg gcaagaaaat ttgtgcaagt tctactgtat cgatgcctgg tatcttcaaa
    27721 ctaggaagtc cgcatcgcat gagttcatgg ttcaaaaaat tataatcaaa ataaatatta
    27781 tgcgcgacaa atatggtgtc tgccaaaaga ttgtaaatcg tttgggcgac atcttcgaaa
    27841 taaggcgctt tttggacgcg ttgattcgtg atccctgtta aatgctggat ttgttttgaa
    27901 atcttccgcc ctggatgaat atcgatcgaa aaacgtgaag tgatccgacc tgattcaatc
    27961 atgacgcagc caaattggat gatccgatct tcttttggat tcgtcccagt cgtttcgata
    28021 tcaacgactg cataagttct tggtttcaaa atatcttcct cttctcctgc ctctaatgtt
    28081 cttttgaaat tatactacaa agtgcagaaa aatactctca tcgcttttta aagaaaatag
    28141 acaaaaacgc ccagacacgc aaatgtctgg gcgtttattt tttagtatag gttaattaag
    28201 ctttagtaac gtttgttgct tgaggtccgc gttggccttc ttcaacatcg aaagttactg
    28261 cttggccttc ttctaaagtt ttgaatccgt cgccttggat agctgagaaa tgaacgaata
    28321 catcgtttcc gttttctgca gtgatgaatc caaatccttt ttctgagtta aaccatttta
    28381 ctgtacctgt ttccataata aaaatcctcc ttgtgtatca acacatattt tgcaattact
    28441 tgaatggtgt atatctggaa gatgtttatt tgaaacaagc taccacagat taccgaacaa
    28501 aaactactcc tatagtatat cataccgttt acaaaaaagc tagagttttt cgactttttt
    28561 tattaaaaaa agttttctca gcgattacat aaagtgaaaa accgaacttt ttttaaaata
    28621 aacgacatat tgttcagttg gtgttttttt gctctgatgt tcttctttaa actaaaaaaa
    28681 ttattctttc tgactactta tcggttctgt ttcaacggtc gaggctgggg aagattcttt
    28741 agtaggtctg atgttctcat ggtatttctg atagcctatg acagttacca gaagaacaag
    28801 gcaaaccaat acgatcaacg agattagttt ttcttttttg ctcatatcta tacctcataa
    28861 ataacaggat gatgtccatc atatttctga gtatgagtaa aagcaaaagc tgcagctgta
    28921 gaatgtaaga aatgccagca actttcataa tcacaggtcg gacagtacca aaagtaacca
    28981 aatcttggct gcaaagaccg ttcttctgtt tcaggaatcg cagaatcaag atctgttgtc
    29041 tgtacataaa catttttgta cagacgtgtg cctgtaatag gagaccgctg tgtttcttca
    29101 gcaaaaactg gctgacttgt taaacttagg gatagaaaca gcaaacacca taacagtctt
    29161 tttttcataa agacctcctt atcgataagt ttttcccaat taaaatcata tctcaagaac
    29221 gcccgttatt cacattttgt tcataaatga tgttttttgt atcataatcg tcaaaaagag
    29281 gtcgtgacca cgtcacaacc tcttttt
//
LOCUS       DBBGSP010000036        29096 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000036 DBBGSP010000000
VERSION     DBBGSP010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.036"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..1030)
                     /locus_tag="ACIZE9_001854"
     CDS             complement(<1..1030)
                     /locus_tag="ACIZE9_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6093709.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="ACIZE9_001855"
     CDS             complement(1112..1801)
                     /locus_tag="ACIZE9_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HGC6093710.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="ACIZE9_001856"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="ACIZE9_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGC6093711.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /gene="rplJ"
                     /locus_tag="ACIZE9_001857"
     CDS             complement(2328..2831)
                     /gene="rplJ"
                     /locus_tag="ACIZE9_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGC6093712.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="ACIZE9_001858"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="ACIZE9_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGC6093713.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="ACIZE9_001859"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="ACIZE9_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGC6093714.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="ACIZE9_001860"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="ACIZE9_001860"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGC6093715.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="ACIZE9_001861"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="ACIZE9_001861"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGC6093716.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7543)
                     /locus_tag="ACIZE9_001862"
                     /pseudo
     CDS             complement(6443..7543)
                     /locus_tag="ACIZE9_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(7635..8522)
                     /locus_tag="ACIZE9_001863"
     CDS             complement(7635..8522)
                     /locus_tag="ACIZE9_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC6093717.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="ACIZE9_001864"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="ACIZE9_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGC6093718.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="ACIZE9_001865"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="ACIZE9_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGC6093719.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="ACIZE9_001866"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="ACIZE9_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGC6093720.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /gene="cbpA"
                     /locus_tag="ACIZE9_001867"
     CDS             9753..10397
                     /gene="cbpA"
                     /locus_tag="ACIZE9_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HGC6093721.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="ACIZE9_001868"
     CDS             complement(10453..10956)
                     /locus_tag="ACIZE9_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGC6093722.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="ACIZE9_001869"
     CDS             11553..12518
                     /locus_tag="ACIZE9_001869"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGC6093723.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="ACIZE9_001870"
     CDS             complement(12617..13789)
                     /locus_tag="ACIZE9_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6093724.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="ACIZE9_001871"
     CDS             complement(13776..14921)
                     /locus_tag="ACIZE9_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6093725.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="ACIZE9_001872"
     CDS             complement(14935..15867)
                     /locus_tag="ACIZE9_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093726.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="ACIZE9_001873"
     CDS             15984..17063
                     /locus_tag="ACIZE9_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HGC6093727.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17678
                     /locus_tag="ACIZE9_001874"
                     /pseudo
     CDS             17060..17678
                     /locus_tag="ACIZE9_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(17788..18015)
                     /locus_tag="ACIZE9_001875"
     CDS             complement(17788..18015)
                     /locus_tag="ACIZE9_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC6093728.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18118..20706)
                     /locus_tag="ACIZE9_001876"
     CDS             complement(18118..20706)
                     /locus_tag="ACIZE9_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGC6093729.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20726..21385)
                     /locus_tag="ACIZE9_001877"
     CDS             complement(20726..21385)
                     /locus_tag="ACIZE9_001877"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGC6093730.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21434..21937)
                     /gene="trmL"
                     /locus_tag="ACIZE9_001878"
     CDS             complement(21434..21937)
                     /gene="trmL"
                     /locus_tag="ACIZE9_001878"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HGC6093731.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22158..23024)
                     /locus_tag="ACIZE9_001879"
     CDS             complement(22158..23024)
                     /locus_tag="ACIZE9_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HGC6093732.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23133..23774
                     /locus_tag="ACIZE9_001880"
     CDS             23133..23774
                     /locus_tag="ACIZE9_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGC6093733.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23836..25197)
                     /gene="mgtE"
                     /locus_tag="ACIZE9_001881"
     CDS             complement(23836..25197)
                     /gene="mgtE"
                     /locus_tag="ACIZE9_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HGC6093734.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25215..26114)
                     /locus_tag="ACIZE9_001882"
     CDS             complement(25215..26114)
                     /locus_tag="ACIZE9_001882"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGC6093735.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26116..26913)
                     /locus_tag="ACIZE9_001883"
     CDS             complement(26116..26913)
                     /locus_tag="ACIZE9_001883"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGC6093736.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26891..27595)
                     /locus_tag="ACIZE9_001884"
     CDS             complement(26891..27595)
                     /locus_tag="ACIZE9_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGC6093737.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27726..28301
                     /locus_tag="ACIZE9_001885"
     CDS             27726..28301
                     /locus_tag="ACIZE9_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGC6093738.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28419..29096
                     /locus_tag="ACIZE9_001886"
     CDS             28419..29096
                     /locus_tag="ACIZE9_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HGC6093739.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8559 a         6167 c         5232 g         9138 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctagt tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgcgaa acccatcgtc ccgatgtttt gctgacggac atccgcatgc
    17221 ctaaacaaac gggcatcgat gctgccaaag aaattttggc taaatttccc aaagccatcc
    17281 ttttgctttt gacgacattc aaagatgaag aatacatccg cgaagcattt tccatcggtg
    17341 tcaaagggta tttaatcaaa cagaacttgc aagcgattat tccttctgtc aaatccgctt
    17401 ataatggaca ggccgtattt ggtaatgaaa tcatcgagac tttcactcaa atgatgaaga
    17461 ataaaccgac gattgatagt catgcttatg cttcttttag tgaacgtgag cttgcaatca
    17521 tcaaagaagt agctgccggg aaaaacaata aagaaattgc agatgccttg tacttgagtg
    17581 acggcactgt tcgcaattac atcagccaat tactagaaaa gctagattta cgggatcgca
    17641 cgcaattggc tatctatttt tatcagcatt tgcaataagt cttatctaac acaaaaaaac
    17701 ctgaatgatg ctccttcgca tcattcaggt ttttttcaca tcttctattc aattgtcccg
    17761 caaaccattt cctcacgatt gaaagaatca aggattcgca gggctgccag gattcgttgg
    17821 attgttcggc gtgttaggcg gaaaaatagg cgccttgtct aacgtttttt ctagttttga
    17881 ttcttcacga tcgtctcgtt ctacatcagg actttcattc aatttgaatt ctttttccat
    17941 ctcatctaac tttttaaagt cattgccaga ttcttttgct aatttcgcta atttatcttc
    18001 ggtttcttta gccataaagt aacgcccccc ttttgatttc agcttagcat atcacactga
    18061 aaaaacaaaa gaaaacgcta accaacgatc atttttagct atttctcatc tttaaaatca
    18121 agcatttttt gccggtataa aatcgtaggg agaactgttt tccataccaa tcatcggatc
    18181 tactaactgg ttatcgatca cttctgctgt aagaacgaaa tctttagaaa cagcaggttc
    18241 tacctcttct ttcttttctt ctccaacaaa tgaagaaaac agatctggtt ccactgtttc
    18301 cattacttgg tttttcgttt cattcgtccc actgtcatct tctacaggta gcttttcttt
    18361 tacaacccgt ggctcttttg tatagttccc atcttcaaat ggatcatttc cgaccaaaga
    18421 atcttcataa gctgctagtt tggtccggag agtgatattc attttatcat tatccatgat
    18481 ccttgatttc aacgtagtca tccggcttgc tgattcattc gctacacaag tgacataggc
    18541 ttgctcttcc cctaacaaaa tcaacagttc cttactgcga gtcactgccg tgtagagcaa
    18601 attacgctga agcatccgct gatattgatg gaccatgggc aaaataacca tcttgaattc
    18661 actgccttgt gatttatgga ttgagcaaca ataagaaaga gtgattttat tccattcgtt
    18721 tcttttataa gtgacctcat ttgcatcaaa ctggataact aattcatcca ctttatcttc
    18781 agaatctttt gccaagatga tacccgtgat ttctcccata tctccattga atacattcaa
    18841 ttcgggagta ttgactaatt ggaggacttt gtctcctatc cgataaacgg tgtcgttcca
    18901 atgtacttcc ttttttccag gtttccctgg attgaatatc tcctgcatca ttttatttaa
    18961 cgcatcgatc cctgcaggtc cccgatacat tggtgctaat acttggatat cttgtgcacg
    19021 gaatccctta tttttcgctt tttccacaat tttagagatc aagggttcaa tttgataagc
    19081 atcacttcgg aaataggaac gatctttttg attctttgtg aaatcttttg gcagacgtcc
    19141 ttctttgatc tcatgggcaa gaggaataat actagaacca tcaccttgcc gataaatctg
    19201 attgagttcc attttgggaa tttgttcgat ttccaaaaga tcatggagta cttgaccagg
    19261 accgacagag ggaagctgat ctttgtctcc tactaagata acttgcatat tcgtcggaat
    19321 cgctttgaat aatgtgttag ccagccatgt atcgaccata gacatctcat caacaatcaa
    19381 aagtccgcct tctaattctt tcgtactgac tgaaggtgtt ttttcccgtc cattcagccc
    19441 cagaagacga tggatcgtac tggcaggcag acctgtcgtt tcgttcattc gtttagctgc
    19501 tcggccagtt ggtgctgcaa gtagaatagg aaaaatttct tgggtatatt ttgaaggatc
    19561 caattccagt ccgttcaact ctgcaaaaag attgacgatt ccgttgatca cagtagtttt
    19621 ccccgtacct ggtcctcctg ttaaaataaa tagaggggaa cggattgctt cagcgatagc
    19681 ttgttcttgc gaaggtccat actgtatgcc gaatattttt tcgatacgcc gaatattctt
    19741 ctgcacttct ttttcaggat aatggatttc ttttttacga ctgagaaggc gctggatcga
    19801 attaccgatc ccccattcag aaaagtacaa actgttttcg taaagattag tctcttcttg
    19861 ttgtatcttt ccttcttcaa caagttggat aattacagta gcaacctgat caggctggat
    19921 ttcaattggg cgacttgttt ctaaaatacg gatcgtttgc tgaagcaatg tctccgccgg
    19981 tacgtatgta tctcctgttt gaactgcatg ctgaaaaatc tgatgcaaga tagctgctcg
    20041 aattcttctc ggtgaatctg ctgcaatacc gatttgttcg gctagattat ctgcacgttt
    20101 gaacccgatt ccttctatgt cttcgactag ctggtacgga ttttcttcga tgatatccaa
    20161 agactcgttc ttataggcct ggtagatact gaaagctaac tgactaccga acccgtaacg
    20221 attcagtccc atgatcactt gatccatccc gtggtttagc cgaatcgtct cagcaagcat
    20281 ttctcttttt ggcttcgtca aaccggagat ttgttttaat accgaaggat cagcaatgat
    20341 tttttcgata gcatcttctc ccagcaattc tacaattttt tctgctgttt tcttcccgat
    20401 tcctgggaat ttttcgctgg aaagatacgc tacgatccca tttgcagttg ttggcttttc
    20461 ttgctcatat ctttcgagtt taagctgcct tccgtattta ggatgatcca ctaattctcc
    20521 ataaaaacga taagtctcat tttcttgaat atcgccgaaa cttccggtga ctacaatctc
    20581 tttttcacgg taatcagctg tggtttcact gatgtgtacc aaaagcactt tgtaaaaatt
    20641 actaggattt tgaaaaaaaa tcgcggcaac tgtaccaacg aaataaggca tttcttctgg
    20701 ctgcatcgga agccgcctcc ttcttctata gtaaaggttc tggtgctgtt tcagttccta
    20761 aaaaatctgt ttggttccat actttcagtt catatggcaa taatctgcaa ggctcttcag
    20821 tctctaaaat cgtcaaacta ctattgaaca atccacccat ttcacgcaac tcacttagct
    20881 cttttcctgt catccattga atggctgcag ttaaagaagc tccatgtcct acgaataaaa
    20941 gtgggccatc tttatgtcgg gcaaccgcat ctgctacaac agtttcgata cgtgtgattg
    21001 ccgattcaat cgtttctccg tgaaaaggag aaggatcata cagatctaaa tgattacgca
    21061 aattcggcag attatccgga tatttctggt acatttcatc gatcgactga ccttctaaag
    21121 tacccagccc tagttctctt agcttatctg tataaaaaat ctctaccgga cgagcaagct
    21181 ctttgttgat accttctgct gtatcacgtg ctcgctttgc tgtactggaa taaattgctt
    21241 taaaaggaac atattttacc tttttcccaa atgctttgat ttcttcgtaa ctttgtggca
    21301 aaagcggaga atcgccattg ctcccttgaa aacgtctttc ctgattccat tgtgtcttcc
    21361 catgtcgggt aaaatatagt tccatacgca gcaaactcct gtctttcttt tattttactc
    21421 tataataaac tgtctaatcc agcttgtcat tttcatagtg atgcgtcaat tctaaattag
    21481 ggaatccttg ctggcgaagt gcttcataca ctatcattgc agctgtattc gataaattca
    21541 atgagcggac atgctcatca ttcataggga tgcgtaaaca cttttcttcg ttttcacgca
    21601 taaatgtttc tggcaaaccg gttgtttctt ttccaaataa aaagaagtgc tcttctccat
    21661 cagcaaaatt ttcgtcacta tatactttat gggcaaattt tgagatcaaa tgtagtttac
    21721 gattacctaa aaatgttaaa aaagcttcta aattactgtg gtaagtaata tttacatcat
    21781 tccaataatc caaccctgcc cgttttagat gtttgtcatc agttgaaaaa cctagtggct
    21841 cgattaaatg aagcggagta ttcgtggctg cacacgtacg ggcaatattt ccagtgtttg
    21901 cagggattaa tggttcaaat aaaacgatat gattcatcag gatcattcct ctcatattta
    21961 tgttcgtttc tattttctga caatttgatt tttgcataaa aaaaaacgta tcaactcggt
    22021 gtcagtcact gcgagtcgtt acgttagtga agctcttctc actaactttt atcagaacag
    22081 gaacctgata aaaaccaatg aaaaaacaac ttgttgctaa tataacaccc tcaacttttt
    22141 tttgcaacct ctactcatta aaaactgcta gaaaaacgtt ttctcttagt tccttttaat
    22201 aattctatgt caattgtaat cttcttcaaa ggattcttat ataagtctgc tttgattcgc
    22261 tcttctacct gccattctaa aggtgacatg gccaaaagat ctttttgatt ttcctctggt
    22321 atctcaaatt cataggttac acgctgacgt tcagttaatt tcattgcttc agcaaacttg
    22381 gctactacac gttcattgga ataactctgt ttttcaggtt gattcggata aaaagcctga
    22441 cgtagttcct ttaaataatt ttcttgtggc accaccttca acacttctcc atcttctgag
    22501 agtacacgtt ggaattcttg gtaatgagaa ggcgaaaaga tatttaaaac cgcgttgaat
    22561 gtttgatcag caaacggcaa attggtcaaa tcagctacac accaaaatgc ttcggcagat
    22621 tgttctgtag ctgcgtagac tccttctttt gaaatatcaa atccaacagc attttgaatc
    22681 tttttcaatt ttgaaagttc attcaagaag ctaccttctc cgcagccaac atctaatagc
    22741 gagacttctt caggtaaatg ctgcgcaata gtctcaataa cgggctgata catgccagat
    22801 tggatcattc tacgccttgg aacgaacatt ccttgatcgt attctgtttt aaccgcatgg
    22861 gataaaaaat aaagtgttcc ttttttggaa aggtcaaaac ggtgattatt tttgcatatc
    22921 aagccattat cagacttttt tacttcttct tggcaaaccg gacagcggaa cagctgatga
    22981 ttttctgcca aaaactggcg tcctcggtca atttttttta acatagttcc ccctcatttc
    23041 tgttttatct taccgttaga tgctcacttt ggcaactgct aaaaatatga tacaatgcct
    23101 agaagaaagt gaaagataaa ggagaagatt agatgatcaa agaattttgc gctgaaaact
    23161 acacatctat tcctctagca attgctagag gagccgatcg gatcgaattg tgtgacaact
    23221 tagcggtcgg tggcacaacc ccgagtactg gtgtgatcga agaaacgtta agttatgctg
    23281 gggaaaaaga tatccccgta atgacgatta ttcgtcctag agggggcgac ttcgtctata
    23341 acgatatcga attgaaaatc atgcatactg atttgattga agcaaagaaa ttagggacgg
    23401 atggcgtagt atttggttgt cttactcctt caggctggct agacgaagag gccttagaac
    23461 tattgatcga aacagcagaa gggttgcaga tcaccttcca tatggctttt gacagtattc
    23521 ctgaagatcg gcaattcgaa gcaatcgatt ggctggtaga acatggtgtt gaccgtatct
    23581 tgactcatgg cggtcctgct gacaaaacta ttgtagaaaa tttcccacgg cttaaagaat
    23641 tgattgccta tacagatggc cgcttaatca ttttgcctgg tggtggtgtc actgcagaga
    23701 atgcagcaca tgtagctaaa gaattgaacg taagcgaagt acacggaacc aaaatcgtgg
    23761 atcttcagtt ataatcttat aaacaaaaaa acatttgcaa caggcataat gcttattgca
    23821 aatgtttttg tttttttaca taaaatagcc cataaataaa gaagcaatat tgaaataaat
    23881 cagtacactc gtcaaatcgc tcaaagtcgt gataaaggga ccgcttgcta ctgctggatc
    23941 aaatcctaga cgatccatta gcatcgggat taaactacct gcaagattcg ccactgtgat
    24001 tgcaaatagc atagccatcc ctatgacaaa ccccaagata aaattatgtt tccaaaaacc
    24061 tacgattaga aaaatcgtga tccccgtaac agctcctgtg acaacgccgg tcaagacttc
    24121 agccaaaaca agtcgaacaa atccatgatc tttctcatca gaaatcgcaa gtcgacgaac
    24181 agccacagct agcgactggg ttccagcatt accggcagtt cctgtaatca gcgaaatgaa
    24241 gactgctaaa atactcgctt cacttaccaa gtcttcatag tgactgatta aagaagcggt
    24301 cgacatacct aaaaacaaca gagtgatcag ccaaggcaaa cgtcgagacg ctgcctttac
    24361 tggattttca ttaatttctt ccacattgac cccggcaagt cctgaataat cgctagcagc
    24421 ttcatcatca ataacgtcga tgatatcatc gactgtgacg attcctaaca aatgatcatc
    24481 ataatcggta acaggaagag ctaagaagtc ataatctcta aatgtttgtg ccacatcttc
    24541 ttggtcgtcg cctacatgaa ctgaaagcac tcgttcgctc atcagatcag aaatcattgc
    24601 gtcgtcatca ttcacgatta ggtcgcgcag agaaataacc cctactagct gaccttcttg
    24661 attaacgaca tagatgtaat agattgtttc agctacatct gcttcgttct tcagcacgta
    24721 catcgcagag cgaacagttt gattggctac gatcgaaaca aattcagttg tcatgatcgc
    24781 gccagccgtt tcatcctcgt aatggagaag ttccttgatt tcactggcat cgtctgccga
    24841 catcaaactt aaatatttag caatttgctt tttatccagc gtattaagca agtcaacagc
    24901 attatctgta tacatctcag aaagcatatc agctgcatag ctaggacgca tttcatctag
    24961 gtattctttc atatgttcgt tgtcttcttc aatcacatcg aacatatccg ctaattcttt
    25021 aggcgacaga taggaataga tcagctgcct gttctcttct gtaagagatt ggtagaattg
    25081 cccctgctca tagatatgca tctctaaaaa actgtttctg aatgcctgaa tattattttc
    25141 ccttaaatct tgagtcaact gggcaaatct ttcctctaat tcttgatttt catccaaacc
    25201 aatctcacct cgccttattc ttcaaaccgt ctcacaactg cctccatgtc tgcggctaaa
    25261 ggctgcttga actccagcaa ctcttctgta aatggatggt aaaaacgcag atcataacaa
    25321 tgaagggctt gtctttttat tcccagatcc attcgcccgc catacatatc atcaccgagc
    25381 agggcacagc caattgcgga aaaatgaact cttatttgat gtgtccttcc tgtatgcagc
    25441 tggatatcaa ctaacgcgat ttctgttagt cgcttctcta tccagtactc agtctgtgcc
    25501 gaacgtcctt catcagagac cattcgcttc aatagcgaag aataatctcg ggcgatcggc
    25561 aaatcgatat gtccatgtgc cgataaatct gaaagccttc cactgactaa ggcctgatat
    25621 tttttcacaa acttcttttc acgaagttgc atatctaatt ttgcgtgcgc aaatccatgc
    25681 tttgcaaaaa gcatcaagcc agatgtatcc cgatctagtc gcgtcaccac atggattact
    25741 tggttttcgt aaccttgttt tttataataa gcctttacac gattagccat tgtcccattt
    25801 ggatggtatt gggcaggaat agacgaaacg cctgctggtt tatttactac cagaacgtgt
    25861 tcatcttcat acacgatatc gatcggtgtt tcatccaaaa gtacggtttc atgttctcct
    25921 tcagcaggaa tcacaatggt taccttatca tccttagcta gagaaaacaa gacattttct
    25981 acttgatcat taactttgat ttgaccgcct tgaaatttta ttttcgctaa cagacccttt
    26041 gagatccctt tttcttttaa aaaatatttt acttgctgag aatgatcttt ctcataatcc
    26101 catgtaaact gcatatcaat cctcactaat aaaggcatct ttcacacgat gccaaaaatg
    26161 catatgtcga taagaagcaa aatggatccg ttcttctgct attcgataat aaattgagcg
    26221 gatatttgct tttgcgacat tcaattgatc aaccgttaca agataatctt ctgtattttc
    26281 caattttatt tctagccatt catcatgggc aatcacgatc ggagaaccca aagtacgaaa
    26341 cactcgatta ttcagtgaag caatctctgc caactgaaag gcattgatac taggatggat
    26401 cacagcaccg ccgacacttt tattatatgc tgtcgaacca gtaggcgtag aaatcgtcaa
    26461 tccatctcct ctaaaacttt caaacagctc gtttttgatg tatacatcgg ctaccatcgt
    26521 acgattggcc cgtttaatcg ttgattcatt cagtgctaaa aaatgctggt ccggtgtttc
    26581 atccaaataa ctgatccgaa catccagcaa gggataacta acactttgtt cccggttcgt
    26641 tcgtaagctg tctactagtt cttccagctc gtaatcccgc caatccgtgt aaaaccctaa
    26701 atgacctgta tgcacgccca agaaacgcac atcattcaga caatgactgt agtgatggaa
    26761 cgccgacaat aatgtgccgt ctccgccgac tgagatgacc aattctggct catgatcatc
    26821 tcgttgaatc cctgcttgtt ctaaaagtgc gttcaaacgt tctgtcactt ctatagtctt
    26881 tgcttcttta ttatgaacga tcgctacttt catcccctgc ctcctctctt tcgctttctt
    26941 tcttcaaaag cgttcgatag tagacatcat ctgattttcc tcttccatgg gagaataacc
    27001 gctgtgcttc ttggatttct tcacggatac tggacatctc ttcatccaac tgataggcag
    27061 cttctgccgc acgctgaagt cgttcactca tttcttctgg aaaaacgcct tgatatttat
    27121 aattcagcga atgctcaatc gttgcccaga aattcatcgc aagagtccga atctggattt
    27181 ccgccaaaat tttcttctca ccgctgatca gctgtacagg atactcgatc accagatgat
    27241 aagaacggta gccacttgct tttttatttg tgatgtaatc tcgttcttgg agaactttca
    27301 tgtcttttct tttacggatg atctcaacaa cttgatggat atcttctaca aactgacaca
    27361 tgatccttaa cccggcaata tcagacattt cttcttctaa acgtcccatt ggaatatgcc
    27421 gtaattgtga ttttgttaca atactatcga ctggcttgac tctcccagtg acaaattcaa
    27481 tcgggacatg tcgattttgt tcacggaact gtttgcggat cccccgcagt ttcactttca
    27541 attctgatac agtttgttca tatggtgcta aaaatgcttc ccaatctcgt tccatagctg
    27601 atacctctac ttcattaaca ttcattgttt attctaccat atatgcaaag ttttttcgta
    27661 ctcttgattt atgcattgac caaaaaaaga aaattaggca aaatagacaa aaaggagtcg
    27721 atcaaatgac acaaatgctt gaaatcgaat ataaatctat gctgacaaag caagagtacg
    27781 agatattcat cgctcactat caattaacag ataaagattt ccgtgtacag actaatattt
    27841 atttcgatac cgttgatgaa cagctgaaga aacaaaattg tggcctacgg atccgtttcg
    27901 ttggtcatca agctgaatat acattaaaaa cacctgctga aaaagggcgt ctcgaaacaa
    27961 cggatacctt tataacagaa gaagcagaag catttatctt cgaaaaacgt ctgcctcgtt
    28021 caggcgcagt ttttcaaaaa ctttctgatt tgaatatcga tcctgcttca ttaatccaaa
    28081 ccggaaagct tacaacaaaa cgagctgaat tccctattga agaaggactt ttagctattg
    28141 atgaaagctg gggagacaat ctacacgatt ttgaactgga actagaggta ggggatgcat
    28201 ctgtgggaaa aattgctttt ataaattttt taaaacgttt ttctttacct tatcgtcctg
    28261 ctaagaacaa gatccaacgt atgcttgaag ctaaaaatta gaaacctttc attttcacaa
    28321 ggcacttgag ttcatttttt tacttttttc tgttaagtta taggatgtga aagaatctag
    28381 tcactagttg tatagaatct attttggggg agattcatat gatcgaaatc tatttatttg
    28441 ttaatccttt aggggaatac tgtttcgaaa tggaacaaca gttattacaa tttatcgaag
    28501 aagagtacgg gacaccatca aaagaaaaga tgcaatttcg ctttcttcct ttggtcaatt
    28561 tgcagacaat tggggatgtc atgcaacaaa aaggaatttc tcagaacaat cttgaggaac
    28621 gtaatcactt attctcaatg acttattctg cagcattgga ctgcaaagcg gcgcagtttc
    28681 aaggaaagaa aaaaggccgc cgttttttga tcaaattgca agaagcagtc ggctgtaatg
    28741 acataccata ttctcaagaa cttgctgaat ccatatttga agaaatcggc ggcgatttga
    28801 atatgtttaa agaagatcgt cagtctgact tcgttaaaga agtattcttt tctgatcaaa
    28861 aaattgctcg ggaaatgggc atcacaaaac acccttctgc agtcgtttac aattatgcct
    28921 gcgaccgtga ttttggtgtt ttagtagaag taaaaggtac aagtagcctt tggagaatca
    28981 cagagctgtg taaaacaaca gataactcat atcaagtttt taatggtgaa catttacata
    29041 caaatgattc tcagttccat tcaagaacta gccatttaca cttgctttct aattaa
//
LOCUS       DBBGSP010000037        29095 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000037 DBBGSP010000000
VERSION     DBBGSP010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29095
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.037"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            278..1063
                     /locus_tag="ACIZE9_001887"
     CDS             278..1063
                     /locus_tag="ACIZE9_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC6093740.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            1076..1927
                     /locus_tag="ACIZE9_001888"
     CDS             1076..1927
                     /locus_tag="ACIZE9_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HGC6093741.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(2051..2503)
                     /locus_tag="ACIZE9_001889"
     CDS             complement(2051..2503)
                     /locus_tag="ACIZE9_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093742.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(2968..3336)
                     /locus_tag="ACIZE9_001890"
     CDS             complement(2968..3336)
                     /locus_tag="ACIZE9_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HGC6093743.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            3486..3968
                     /locus_tag="ACIZE9_001891"
     CDS             3486..3968
                     /locus_tag="ACIZE9_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HGC6093744.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            4005..5015
                     /locus_tag="ACIZE9_001892"
     CDS             4005..5015
                     /locus_tag="ACIZE9_001892"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGC6093745.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(5130..5843)
                     /locus_tag="ACIZE9_001893"
     CDS             complement(5130..5843)
                     /locus_tag="ACIZE9_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093746.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(6016..6623)
                     /locus_tag="ACIZE9_001894"
                     /pseudo
     CDS             complement(6016..6623)
                     /locus_tag="ACIZE9_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            7107..7334
                     /locus_tag="ACIZE9_001895"
     CDS             7107..7334
                     /locus_tag="ACIZE9_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HGC6093747.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            7350..8516
                     /gene="hemW"
                     /locus_tag="ACIZE9_001896"
     CDS             7350..8516
                     /gene="hemW"
                     /locus_tag="ACIZE9_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGC6093748.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILHFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            8750..9793
                     /gene="hrcA"
                     /locus_tag="ACIZE9_001897"
     CDS             8750..9793
                     /gene="hrcA"
                     /locus_tag="ACIZE9_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGC6093749.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            9887..10450
                     /gene="grpE"
                     /locus_tag="ACIZE9_001898"
     CDS             9887..10450
                     /gene="grpE"
                     /locus_tag="ACIZE9_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGC6093750.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            10501..12330
                     /gene="dnaK"
                     /locus_tag="ACIZE9_001899"
     CDS             10501..12330
                     /gene="dnaK"
                     /locus_tag="ACIZE9_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGC6093751.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            12481..13647
                     /gene="dnaJ"
                     /locus_tag="ACIZE9_001900"
     CDS             12481..13647
                     /gene="dnaJ"
                     /locus_tag="ACIZE9_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGC6093752.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(13729..14358)
                     /locus_tag="ACIZE9_001901"
     CDS             complement(13729..14358)
                     /locus_tag="ACIZE9_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093753.1"
                     /translation="MGQLSDNQQLCQERINPLLELLERVFSYYGQALLTVHRQQIIIL
                     VNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSFLHAKQVCEWIAF
                     HQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLFKKTLACFSKNNG
                     SIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLLVQT"
     gene            14370..14543
                     /locus_tag="ACIZE9_001902"
     CDS             14370..14543
                     /locus_tag="ACIZE9_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093754.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(14588..15325)
                     /locus_tag="ACIZE9_001903"
     CDS             complement(14588..15325)
                     /locus_tag="ACIZE9_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGC6093755.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(15327..16829)
                     /locus_tag="ACIZE9_001904"
     CDS             complement(15327..16829)
                     /locus_tag="ACIZE9_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGC6093756.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            17088..19082
                     /gene="uvrB"
                     /locus_tag="ACIZE9_001905"
     CDS             17088..19082
                     /gene="uvrB"
                     /locus_tag="ACIZE9_001905"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGC6093757.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            19092..21908
                     /gene="uvrA"
                     /locus_tag="ACIZE9_001906"
     CDS             19092..21908
                     /gene="uvrA"
                     /locus_tag="ACIZE9_001906"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGC6093758.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            22171..23436
                     /locus_tag="ACIZE9_001907"
     CDS             22171..23436
                     /locus_tag="ACIZE9_001907"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HGC6093759.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            23440..24171
                     /locus_tag="ACIZE9_001908"
     CDS             23440..24171
                     /locus_tag="ACIZE9_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HGC6093760.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            24306..25190
                     /gene="rapZ"
                     /locus_tag="ACIZE9_001909"
     CDS             24306..25190
                     /gene="rapZ"
                     /locus_tag="ACIZE9_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGC6093761.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            25187..26185
                     /gene="yvcK"
                     /locus_tag="ACIZE9_001910"
     CDS             25187..26185
                     /gene="yvcK"
                     /locus_tag="ACIZE9_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HGC6093762.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            26219..27154
                     /gene="whiA"
                     /locus_tag="ACIZE9_001911"
     CDS             26219..27154
                     /gene="whiA"
                     /locus_tag="ACIZE9_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGC6093763.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            27697..28347
                     /locus_tag="ACIZE9_001912"
     CDS             27697..28347
                     /locus_tag="ACIZE9_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093764.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            28534..>29095
                     /locus_tag="ACIZE9_001913"
     CDS             28534..>29095
                     /locus_tag="ACIZE9_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HGC6093765.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT         9565 a         4896 c         6176 g         8458 t
ORIGIN      
        1 aaggggctgt gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa
       61 gtagcttctt cggaaataag ccgaaatttc ttgaagctga ccacttctgt cacaacctct
      121 ttctttatag aaataaaagg acactagcaa ttcatgaaaa cgattgctag agcgtatcat
      181 ttgctttaga ctatatatct tggtgtacac tcactttaag gcggaaataa aagttatccg
      241 taataacagg tttaggtatg aaaaaggagt gggtactatg tacaaggaat tagaaaacaa
      301 agtcgcagta gtaactggtg gctcaaaggg gattggaaca gcgattgctc aacgattcgg
      361 gaaagaaaaa atgaatgtag ttgtcaacta taactcggat aaagaaggag cagaaaaagc
      421 agtcaaagca atcgaagagg caggcggaaa agcagtctct gtacaagcag atgtcagttc
      481 tgaagaagga atacagcgtt tacttgatac ggctttagaa aattttggga cactggacgt
      541 ttgggttaat aatgctggga tggaaaatca gcatccaacc catgaactta gccttgaaga
      601 ttgggaaaga gtgttaaaag tcaatttgac tggcgttttt atcggaacga aagcggcttt
      661 aaattacttt acagagaata ataaaaaagg aaatatcatc aatatgtctt ctgttcatga
      721 acagatccca tggccaacgt ttgctcatta cgctgcttca aaaggcgggg taaaattatt
      781 taccgaaacg gtagcaatgg agtatgcacc gaagggaatc agaatcaata gtataggccc
      841 tggtgctatc cgtacaccta ttaatgcggc aaaatttgat gatcctgaac aaaaagaact
      901 cttggaaagt atgatcccac taggacgcgt aggtgaacca aaagaaatag cggcgacagc
      961 tgcatggttg gcttcagacg aatccagtta tgttacaggt attacactat ttgcagatgg
     1021 tgggatgact ttatatcctt ctttccaagg tggaaaagga taagggtgaa taaaaatggg
     1081 tttattgatt gcattgatcc cggcagttgg ctgggggatc cagccactga ttttgaaaaa
     1141 gattggtggc agaccaacaa atgagatatt aggaactggt attggagcgg tgcttgtcgg
     1201 cttactcgtt caattattcg cttctccagc tggtatttca gtgactacat ttttgattag
     1261 tttactttct ggtgcatttt gggttattgg acaaacagga cagtatacat ctttcaactt
     1321 gattggtgtt tctaaaacga tgccaatttc gactgcatta cagttagtcg gaacctcgtt
     1381 gattggtgtc ttcgcttttg gagaatggtc tggaagtatg gggaaaatca ttggagcagc
     1441 agcaatcatt cttcttgtat ttggttctgc tttaacggca atcagtgatg atcctggaaa
     1501 aaaaggcggt atcacaaaag gaattagtct attagcatca acaagtattg gttattgggt
     1561 atacagtgca ttgcctaaac tagttgatgc aagcggactt tccattttct ttccgcaaat
     1621 gatcggtgtc tttttagggg cagtgattta tgtgattttc cgtaaaccaa ccgcattttc
     1681 tgaagacaag agttggaaag caacgatcgt tggagccatc tttagtgtgt cagcattggc
     1741 ttatattttt tcagcaaatg aaaatggggt tgctactgca tatatcatta cacagctaaa
     1801 cgtagttatc tctacattag gcggtatgta catcctgcat gaaaataaga caccaaaaga
     1861 aaaaaaatta acgattatcg gattattgct gatcgtagta ggaagcatgg tcacggtctt
     1921 tatttgagga taaagatggt aaaatttcat ttattaaaaa aatatttgtt tgaaccaaac
     1981 agtaagtact tataaaaaaa tagcgctaga atttccaaca tctctggaat ttctagcgct
     2041 ttttaattgt ttaagataca agggaaatat ctgtctggat caataatttt tcattgatcc
     2101 attgactaaa gtttacgaca taattgaagt taccaccgat tagtatctcc gcatgattgt
     2161 ctttataaag atcgtattgt aaaagacggt cttttttatt tgcgtaaaca tcgttatggt
     2221 actggactaa ttgttctcgg aattgattga ttgctgtaaa atcacgatat tgaaggttga
     2281 aacgcatcgt gattggtgca tttagcatga atcgctgcat ttcttttgct gcttcctctg
     2341 cttgatctcc gtataggaac tcaaaaagat tacgttcaga aaatttccat tgcccgccaa
     2401 cctttgttcc ttttagtttt ccttcatgaa gataatttct gatagaacgt gtagtaacac
     2461 ctaattgttc ggctaattca tttactgagt aaaaatcttt caatgttcac cctcctatgt
     2521 gaatggttct actgacttag ttgatatttg cttaatcacg aaatgtagaa agaacgattt
     2581 taattaaggt cattgtaaaa atcaagtcag aaaattctaa cttttatttc tctaaagaaa
     2641 ttcgttctct cctaaagtga tattatattt aaatatacct gaaaataatg ggcagtatta
     2701 tgaaagatca ctgatatttt ctcgtatttt ttccttattc aaaagttttg caggaaaatt
     2761 gctgaaaaaa taattttact aagtagaaaa ttcaaagcca ttcaatcagt gatttttttc
     2821 agcacaagaa agactcctta taaaaatagc agatactttg tcaattaagt gtttaaccag
     2881 ggatgataaa aaggatagga ttgaacaaaa cctgtataag gtgatgaata gtttcctcgc
     2941 cagtaaaagg tttattcgta taaagcttta tcgccaaaat ttatcatgac cttttttatc
     3001 ttcaatatta aatgaaatca attgttcaat caattcccag ttgattacac ttttccaagg
     3061 aactttgatg acgttatccg tatatacgta gcctgcttct tggatatttt tttcaagggc
     3121 acgaatcgct gctttttccg gtgcgataga aaaatgattt ttagcaaaac taaatgcaat
     3181 aataaaggta ccatggtcag taaacatagg ttggttccat tttacagttg tgtctagctg
     3241 gggatacgtt tctgttatct tagcaaaaag gtctttgatc ttttgttgat gttctttttc
     3301 tttgatttga ttgatgatcg gctgaaattt ttccattcta aaacgcctcc attaagtggt
     3361 ttgatttatt ttaccagaaa aacaatagtt atgtataaaa aacgaacaaa acacaagtaa
     3421 tgttgtaacc gctatattta tatgataaga tgtctcaaat aataaaatag aaaagagaca
     3481 taaaaatgat tgacttggca aagaaattct tacacgaaaa tatatatttt gagttgtatc
     3541 atcatcgagc catttataca aatgaagatg ctttggtaat aaagaaagaa caaggattta
     3601 caggtacaga gaccaaaagc ttattcttaa aagataaaaa agataataac tacgtatatc
     3661 tgacttttac tacgaaacaa acggatttca aagcattagg gaagatcgtc ggtaaaaggc
     3721 tttctattgt ttcatcagaa cgcatggaag aacaaacggg acaaaagcag ggcgctgttt
     3781 ctccgtttgg ttatgaaaaa cagattccga ttattattga tgaagagctc ttatcaaatg
     3841 aaaaacttgt ttttgcacca ggtagaccag atcaaacgat ggtcatccaa acggttgact
     3901 taaacaaaat catccagcta cttgagatgc cgatattttt gatgccggca aacgaaaaaa
     3961 acaattaacc aagtaaaata gtgcatactt ggaggtgaag caacatgata agttatccat
     4021 tattagaaag aaatgcaacg attggggtta ctgcaccatc ctcaggcgta tcagaggaac
     4081 accattcgtt actcgaatca gctttaaaga gaatggaaga aaaatctttc caagtagtta
     4141 ctggaaagac gctttggacg caagataagg aaaaatcagg tccagcaaga aaacgagcag
     4201 atgaattcaa tcaaatgatg caagatgaaa atatccaaat gatctttccg acttggggag
     4261 gagaattatt gattgagatt ctcgattttg tcgattttga tgctctacaa ccaaaatgga
     4321 tagtaggtta ttcagatatt agtacgttgc tacttgctgt cacattaaaa acagggatag
     4381 ccactgcaca tggaactaac cttattgatt taagaggaga gtacttggat gaaacgacag
     4441 caatgtggga aagtgtactg aaaacaagag aaggagaatc gattctacag caatcttctg
     4501 aaaagtatca aaaagtgtgg ccccatgagc attcatcatc ttctgttttc catctcactg
     4561 aaccaacaaa ttggcaatca gtcagcggag atgcagtaag gatgaaggga cgattattag
     4621 gtggttgtat tgatacgatc aggcatttaa tcggtactcc ttatggagat gtccaatctt
     4681 ttaaaagaaa gtataatgat ggaaagccga tcttgtggtt tctagaaaac tgtgagctat
     4741 cgtcagttga tttaagaaga tcacttgttc agatgaaact ggcaggctgg tttgatggca
     4801 gctcggggat catgttcggt agaagtgcgg cagaggattt gttagattat aaaatgaagg
     4861 atgtatacga agatctgtca aaggaattaa aactaccgat cttgtatgat attgattgtg
     4921 gtcatgtacc gccacaactg acattgatta atggtgccta tgcagaagta gcggtagaag
     4981 atagaaaagc gactgttttg caaacgttta tttaaaaaat tttttcctgc cttggagtct
     5041 atcaaagacc aataaatcta aatagaaaag aaagtgaaag aagctgacaa aatgctgtca
     5101 gcttcttttt gtataacata ttagaaagtc taattatcta taactgtcac atcgattaac
     5161 tgtttcacgt cattgggatt tcctgtagga atagctacta cagatgcatt atcaatgatt
     5221 tcttgagttg tttctctaat gaacgctgga taagatgttt gatctgcagg catttgccaa
     5281 tgtgaaggaa ctggataact agtgattgtc ccgtcatggt tacttgaata cactaaaact
     5341 ccctggtaac tgtatttccc agtgagcata accacatctt tcggatagac tgcactccct
     5401 gcatcataag gggcgatagg tgttcctgca ggataatgaa taacatgtaa ttcgaaatca
     5461 cccgatgtat ctctaaaagt attacctcta atagctagcc aaacacgtgc gtactcaatt
     5521 tgtagatcag aatatcctgc taacggatct attgactgag aagactgtga ggaggttgtg
     5581 tctattgttg aagaagaaat atttgtctca actgtactac tagatgtaga agaagtattg
     5641 ggctctgaga ctttactgct tgttgaagat gtattcgttt cagtagaagc tgatttctga
     5701 gtacttgatt tttcagctga actggtttgt ctgattgaac ttttgtctgt ggtcgcagat
     5761 ggatcactat tttctttact aggagacgta catcctacaa ggaataaaga gaccaacaat
     5821 aaaataaaac ctaacttttt catataaaat acctcattat ttttttaata ccagtatagc
     5881 ataatcctga atttttgaat ccgtaaaacc ttgtctatga atataaatag agtgtatctt
     5941 ctttgataaa tgtcagaaaa agtgtgacaa ataatcatca gtaaaattac ttgtcacact
     6001 attgataagg agtatttaat tgaagagaat gattaggaga aaggatctcc gtacttttta
     6061 tagtaatcat agaatccaag tttgtataga cgaatcgttt tttctcttat ttcttctgtt
     6121 tcaaaatgga ctgcttgaag aatcaagtct gtgaattcta taggagctgt tccattcgca
     6181 gtaatcaaat tacgatcttt cacagcttgt tgttctataa aatcttcttt attctgataa
     6241 ttttccgatt ctaaccaagg aaattgcgca tttccggtgt gtttgtaacc ttgcaataat
     6301 ccgctctgag ctaaataatc aactgcccca caaatagcag ctactggtac gtctgttttt
     6361 aacaatttat cgattatttg atataaatga tgatttttta tgtcccatga attgccaccg
     6421 atcataataa aaaggtcaac tttttcaggt atttgttcga ttaagtaatc gatttttgtt
     6481 tttaatcctc caatggaagt gacctctgat tggatagaag cagttttgtt ttgccatttc
     6541 tcattttggt ttagtgtgct agtaatataa gcaccttccc aatcggcata ttcctctaat
     6601 agaaacgtaa tcgcagtttt cattttcaag ctctccttta ctatctataa caaggacaac
     6661 agttttaacc tacagacatt cattaaaatt gggtagcgac agcgaaaaca acaattctta
     6721 agttttagac agagtataca gatagtcaac ttaattaaat acgaactaaa taaaaatgac
     6781 aggtaatcat ttttgtttac cagcattata acattttgca tacatggatg acaaaagaac
     6841 caattcccac ttgcttgagt acaatattaa aagaaactgg aaggcaaaaa gtaattatag
     6901 aaacgaaaaa taaatcatat cgggcactca gacatgaaaa caaccctaga gatatataac
     6961 taggtaacca gtttaatgaa agaaaaaatc atccaagaag tcgattcttg gattttttag
     7021 tggatttgtt cgccaaatac gtttagtatg cgtatatgag aggttgtaag caaagcgttg
     7081 tggtctgagc acttaaggag gaatctgtga aaatagcttt tcatattttt gcagattttg
     7141 acttaatgcc gaaggtcagc tttgcgatta ccgtttatcg agaggctgta aaagcaccgt
     7201 gtagctccga tgacaataag caagcatttt tagagctagg tttccttgat tctaaatatg
     7261 cggcttattt caatgagttg gtgcttgaac gcgattttaa gaaggtcgaa aacaggcacg
     7321 acttttcgac gtaaggagaa agaatttcaa tgatagaaac aataaatccc gcagaaaaca
     7381 aggtttctgc gtacattcat atcccatttt gcgagcatat ctgctattac tgtgatttta
     7441 ataaagtttt tttagaaggg cagccagtag atgagtatgt ggaaatgctg ctgaatgaaa
     7501 tgaaaataat gctagaaagt catccgacag cgaatttaga aacactttac gtagggggcg
     7561 ggacaccaac ttctttatct gctaaacaac ttgatcgact gttatcaggt gctagagaga
     7621 tcctgcattt tcaaaatggt aatgagttta ctgtagaagc gaatccaggt gatttgaccc
     7681 gtgaaaaact tcaagtaatg aaaaactatg gcgtcaatcg tttatccatg ggagtgcaga
     7741 catttgataa tcgcttattg aaaaaaattg gacgtaaaca caccgcagaa gatgtgtatc
     7801 aaactatgca atttttagaa gcagaaaatt ttaccaatgt aagcatcgat ttgatttatg
     7861 cattaccggg acaaacacta gaaggatatc tggatacttt ggaaaaagct ttggctttgg
     7921 atctgcctca ctattctttg tactcattga tcctcgaaaa caaaacaatg ttcatgaact
     7981 gggtacgaca aggaagactc gaactgcctg atcaggaaac ggaaaccaga atgtttgaag
     8041 agacgattga agcaatggaa aagcatggac gtcaccaata tgaaataagt aactttgggc
     8101 tctccggaca tgaatctcaa cataacctca tgtactggaa caatgcccac tattttgggt
     8161 ttggagctgg tgctagcggt tatcttggag atattcgtta ccgcaacaaa ggaccaatcc
     8221 aacactattt acgcccatta cgagcaaatg aacgcccggt attggaagaa gaaaaattga
     8281 cacgaaaaaa tcaaatagaa gaagaaatgt tcttaggact aagaaaaaaa acagggatta
     8341 ctaaaaaaca tttctatgat cgctatcaaa aaacaattga atcggtgtac ggtgatgtgc
     8401 taagggaatt agagcaagaa gggttacttg ttaatgaaga agaccgtgtt tatttgacac
     8461 caagagggac ctttttgggg aacaatgtgt ttgagcgctt tttgtttgaa aaatagttta
     8521 aagaatattt gttttttatc tgaatttaaa taaaaaaagt tcaaaaatac aataaaggac
     8581 tattgaaacg ttgatataac tggatttaca tcaattattt agaattagca ctcttgtgtt
     8641 tagagtgcta aaaaatggag tctttctctt gacaggagaa gggcttcttg ctatatttat
     8701 aagtggatta gcacttagaa tatatgagtg ctaatgagag gtgaggaaga tgttaacaaa
     8761 gcgacaaaac gacattttac gtctgatcat ccaacactat acgagtagtg gcgtgcccgt
     8821 tggttccaaa acattgatgt ctgagggagt caaggccagc tcagcaacga ttcgcaatga
     8881 tatgaaagca ttagaagatg aaggattgct gttgaagact cactcttctt ctgggcggat
     8941 tccatctgct ttaggctatc gttattacgt ggatcatttg ttaaaacctg ctcgcgtagc
     9001 agaagatgat ttgctgctga ttcgtcagtc tctaggcaga gaatttcatg aaatcaatga
     9061 gattattaag caatctgctg agatattatc tgagctgaca agctatacga ctttttcatt
     9121 gggacctgaa ataaaagacc gccgactgac tggctttcgt atcgtaccct tgaataatcg
     9181 acagattatt gctatcgtcg taacagatat ggggaatgta gaaagccaag tgttcactct
     9241 tcccgaatat atgggaagtc aggaactaga aaaaatggta cagattgtaa acgaccgtct
     9301 agtcggagat cctctgatga cggtgtacca taaacttcgt acggagattc cgatgattct
     9361 tcataaatat ttccaaacga cagaagggat gtctcagtta tttgacaccg ttcttggtca
     9421 tgtttttgaa gataaggttt atgtcagtgg acaaatgaat ctcttggatt atgagccccg
     9481 tcaagatctt gatcagttca aatcgatgtt ttcttttatg aaagactcag acggacttac
     9541 acaaatgatc actccgatgg atagcaatat tcatatcaag attggtgctg aattaggcaa
     9601 tgatttattg cagaatatga gtatgattca agcaagttac gagatagatg gtcatggaag
     9661 aggtacaata gccttgttag ggcctactag tatgccttat tctcggatgt tcggtctagt
     9721 cgatgtttat cgaagagaac tagcagctaa acttgctgat tactaccgtt cgcttgactt
     9781 gtcaaactcg taatgtgaat aacgaagcta tttgcagctg atcgttctct ctttcttagt
     9841 aagagcaatc aaacagctga ctgaataatg aaaggaagac tgtatcgtga aagaaaatca
     9901 agaagaacta gataaagaaa tgacagatgc tcagccagaa ccggaaatcg atgtcgaagc
     9961 tgcagaagat tcgggtattt cagaagctga agcggaagaa ttcgaaacag cgaaattaaa
    10021 agctgagtta gaagaaatgg aagataaata cttgcgggct cgtgctgaaa tcgcaaatat
    10081 ggcaaatcga ggaaaaaatg agcgtgagca attacaaaaa taccgttcac aagatttagc
    10141 caaaaaatta cttccatcaa ttgacaacct ggaacgtgca ttagccacag aagtgtcaga
    10201 tgatcaaggg gcaggtttga aaaaaggcgt ggaaatggtc ttggaaagtt tgcgtaacgc
    10261 actggaagaa gaaggaattg aaaaaatccc tgctaaagga gaagcctttg atcctaatct
    10321 tcatcaagca gtacaaactg ttccagcgac tgaagataca ccagccgata cgattgtaga
    10381 agtactacaa gaaggctaca aattacatga tcgcgtgtta agaccaacca tggtcattgt
    10441 tgcacaataa ttgtgcggat ataaaactta cactttcaat taaagaagga gacgttaatt
    10501 atgagtaaaa ttatcggtat tgacttaggt acgactaact ctgcagtagc agtattggaa
    10561 ggaaacgaag caaaaatcat cgctaaccca gaaggaaacc gtacaacacc ttctgttgta
    10621 tcattcaaaa atggagaaat ccaagtaggg gaagttgcaa aacgtcaagc tgtgacaaac
    10681 ccaaatacga tttcatcaat caaacgccat atcggtgaag caggttacaa agtagatgta
    10741 gaaggtaaat catatacacc acaagaaatc tcagcaatga tccttcaata tatcaaagga
    10801 ttcgcagaag actatttagg tgaaaaagtc gaaaaagcag ttatcactgt gccagcttac
    10861 tttaatgatg cacaacgtca agcaacaaaa gatgctggta agatcgctgg tctagaagta
    10921 gaacgtatcg tcaatgaacc aactgcagct gctcttgcct atggtttaga taaaacagat
    10981 cgcgacgaaa aaatcttagt attcgacctt ggtggcggta cttttgacgt atctatcctt
    11041 gaactaggag acggtgtctt tgatgtattg tcaacagctg gcgacaacca tctaggtggg
    11101 gacgactttg ataacaaaat catcgactac atggtagcag aattcaaaaa agaaaacagc
    11161 attgacttgt ctcaagacaa aatggcttta caacgcttga aagacgctgc tgaaaaagcg
    11221 aaaaaagatt tatctggcgt atcaagcaca caaatcagct tgccatttat cacagcagga
    11281 gaatctggac cattgcattt ggaaatgaca ttgacacgtg caaaatttga tgaattaaca
    11341 gctgacttag tagaacgtac aaaagtacca gtacgtcaag cgctaaaaga tgcaggttta
    11401 tcacaatcag aaatcgacga agttatttta gtcggtggat ctactcgtat ccctgcagtt
    11461 gtagaagcag tacgtaaaga aacaggaaaa gaaccaaaca aatcagttaa ccctgatgaa
    11521 gtagttgcta tgggtgctgc tatccaaggt ggcgtgatca ctggtgatgt gaaagatgtt
    11581 gttttacttg acgttacacc attgtcatta ggtatcgaaa caatgggtgg agtgttcact
    11641 aaattgattg accgcaatac aacgattcca acaagtaaat cacaagtatt ctcaactgcg
    11701 gcagataatc aaccagcagt agacatccat gtattacaag gtgaacgccc aatggctgct
    11761 gacaacaaaa ctctaggaag attccaattg acagatattc cagcagctcc tcgtggtatt
    11821 ccacaaatcg aagtaacatt cgatattgat aaaaacggga ttgtaaatgt atctgcgaaa
    11881 gatctaggta cacaaaaaga acaaaaaatc acgatcaaat cttcttcagg tctaacagac
    11941 gaagaaatcg aacgtatggt aaaagatgca gaagcaaatg cagaagcaga taaagctcgt
    12001 aaagaggaag ttgacctacg taatgatgta gatgcattgc tattctctgt ggacaaaaca
    12061 ttgaaagaat tagaaggcaa agtggacgaa gaagaagtga aaaaagcaga aacagctcgc
    12121 gatgaattga aagccgctgt tgaagcaaac aacatcgaag aaatgaaaac taaacgcgat
    12181 gcattgaacg aaatcgttca aaacttgact gttaaactat acgaacaagc ggcacaacaa
    12241 caagctcaag aaaacccaga agcagctcaa ggcggagcag atgatgtcgt tgatgctgat
    12301 tttgaagaag tcgatggcga cgataaataa tcagttcact gaatttcgag agaaggccaa
    12361 agttgctact ttggcttttt cttttgaaaa atagtttgaa gtatcggttt ttgtttcaaa
    12421 caaaatatga tatgataaca agcgacgtga aaatgatgag aaccaatagg aggaaagcct
    12481 atggcaacaa aacgtgatta ttatgaagtc ttagggctct caaaaggagc atcagaagat
    12541 gaaataaaga aagcttatcg taagctttcg aaaaaatacc atcctgacat caataaagaa
    12601 cctgatgcgg aagaaaaatt caaagaagta tcagaagcat atgagatttt aagtgacccg
    12661 caaaaacgcg ctgcatatga ccaatacggg catgcaggca cagatccaaa ttacggtgct
    12721 ggtggagctg gtggcggatt tggtggattc ggcggcttct ctggtggcgg cttcggtggt
    12781 tttgaagata tcttcgactc tttctttgga ggaggcggtc ggtcagtcga tccaaatgcg
    12841 cctcgtcaag gtgctgattt gcaatatacg gtcgacttgt cttttgaaga agcgattttt
    12901 ggtgtagaaa aagaaatcaa gtataatcgg gaagaaatct gtcatacttg tggtgggaac
    12961 ggtgcaaaac caggcacaca accaactact tgtcataaat gtcatggtgc aggtacgatt
    13021 aatgtagaac gccaaacacc acttggacga gtgatgagcc gtcaaacttg tgatgtttgt
    13081 catgggacag ggaaagaaat caaagaacct tgtccaacct gtcatggctc aggacatgag
    13141 aagaaagcac attcagttaa agtgaatgta ccagctggtg tagaagaagg acaacaaatg
    13201 cgtttagctg gtcaaggaga agctggagaa aacggcggac catttggtga tttgtatgtg
    13261 gtcttccgtg tagaagaaag tgatatcttt gatcgtgaag gttctgaaat ttactatgaa
    13321 ttgcctttaa gttttgtaca agcagctttg ggggatgaag tccaagtacc aactgtccat
    13381 ggagatgtga aattgaagat ccctgctgga acacagacag gtacgaactt ccgtttacgt
    13441 ggaaaaggcg ctccgaagtt acgtggtggt gcaacaggcg accaacatgt caaagtaaaa
    13501 ctgatcacac cgaaaaatct aaatgaacaa caaagagaag cattacgtgc attcgctgaa
    13561 gctggcggca tcaaagttga agaacagcaa gaagacggtt tcttcgataa gtttaaagat
    13621 gcttttggcg ggaaaaagcg gaagtagttt ttctagtaaa aacgctaagt cattaataat
    13681 taaaaaccag acgaacaatc atatgttcgc ctggtttttt tgtagttgtc atgtttgtac
    13741 caacaaaaaa gccagcttta gaatatgata atcgtcatag tttctagggg tataaccagt
    13801 gagagaatgg aacttgttca atcgatattg caaggtgttt ttatgaataa ataattcttc
    13861 tgagcaattt ttgatgcttc cgttattttt actgaagcat gccaaagtct tcttgaacaa
    13921 atgtacttct tcttctgtca ggcttttcaa aatacgtttt acatataatg ttcgttgatc
    13981 tgacgggatt gctggtaaaa cgatcccgag gtctaaatct tcaaaaaagc ggatctcgtt
    14041 cacagattga tggaaagcta tccattcgca aacttgtttg gcatgaagga aagattgcgg
    14101 tgtctcttgc tctgtataac aaagcgaccc aattccaaag tttagctgta actgatacat
    14161 tttattaaac tttgtctgga ttttatcaag caatgatagc aatgaggctc tggaaatccg
    14221 attgactagg ataatgattt gttgtctatg tacagtgagc aaagcctgtc cgtaataaga
    14281 gaagaccctt tcgagcaact ccaataaagg attgatccgt tcttgacaca attgctgatt
    14341 gtcagaaagt tgtcccacaa ctacataata tggagaagaa aaatcaagct caattaagtg
    14401 agggtggtat cgactatgta cttgatatca tcaatgaacc gatggtactt tcttatgcga
    14461 tggaacaggt agagcgattg cttgtttgtg caggaaaaca agcgatgcgg ctgatacgat
    14521 taggtgagaa aataagaaga taaaaataca cggtcccttc atggcgaccg tgcatttttg
    14581 gtttttatta aatatttaat actttattca agaaatcttt tgtccgttca ttttgcggat
    14641 tttcaaagat ttgttgaggc gttccatctt ctaaaaagtt tccgtcgtca atgaacatga
    14701 cgcgattggc cacttcttta gcgaacccca tttcgtgcgt aacgataacc atcgtcatac
    14761 cttgttctgc taactttttc atgacgttca agacatcacc gaccatttca ggatcgagtg
    14821 cagaagtagg ctcatcaaaa agcatgatgt cagggttcat cgctagagca cgagcaatag
    14881 ccacacgctg tttttgtcca ccagaaagca tttcaggata catatctttt ttatcttcta
    14941 gaccaactgt ctgcagtaat ttgattgctt ttttctctgc ttcttctcta gattctttct
    15001 tcaggtccat cggtgctaaa atgatgtttt ccaaaataga aagatgaggg aataggttaa
    15061 agtgttggaa taccattccg atatgttgtc tcaccaagtt gatatctgtg cttttatcca
    15121 tcaagtgggc gccgtcaata ataatttcac cgtcagaagg ttcttctaaa cgattcaagc
    15181 aacgcaagaa tgtacttttt cctgaacctg aagggccaat gatacagacg acatctcctt
    15241 cgttgatgga tacattgatg tcgtttaata ctgtgttatc gccgtatttt ttgactaaat
    15301 gctcaactaa gattttttct gccatcttac ttcaccttct tttctaaaac ttttgctaat
    15361 tttgtcaatg ctgtgatcaa aatcaagtac atgatcgcaa tgatcaagta aacatacgta
    15421 ctttgtgttg tacgtgcaac aatgatctta ccagtttgca gcaattcgac tacaccgatt
    15481 gcggaaatga tcgttgtgtc ttttaatgag ataacgaact gattgacgaa tgatgggatc
    15541 atgatgcgta tcgcttgcgg caaaatgatt ttttgcattg tccgattata agaaagacct
    15601 aaacttctgg aagcttccat ttgtccgaca ggaacggcgt tgatcccgcc tcgaacaatc
    15661 tctgcgatat aagcacttgc gttaagagtc aaggtgataa caccagcaag gaagtcagga
    15721 atcgtaaatc caacgatacc aggcaaccca aagaaaataa agaacgcaag aaccatcatt
    15781 ggaattcctc ggatgatatc gacataaata ctagcaattg tgcgaagagc gcgtattggt
    15841 gctacactga ataatccaaa aatcacaccg attactatag ccaaagcaaa ggagatcaaa
    15901 gttaggagaa ttgttctcca aagtcctttc aacaatgctt gatagttgtt ttggataagt
    15961 ccaagaaatg ttgattcatc agcagtggaa gactcactgg aagtttctga accatccgct
    16021 acatattctt taataatctt atcgtattcg cctgttcttt ttaattcttt caatccttca
    16081 ttgaacatat taagaagctc aggattttgt ccttttttaa cggcaaatgc atattttccg
    16141 ccagattctt ttttgatcgg tgtttccaat tcttgtcctt gtttgatcgc ataaccgatt
    16201 accggataat catccatcat tgcatcgatt gcgccaactt ttaacccgtc gtacaattga
    16261 tcagcagcat caaaatattt gatagaatag ccatattcag attcatggtc gcttaaaaat
    16321 tcagcacttt cggtaccaac ttttgctccg actgtttttc ctttcaaatc ttcataagac
    16381 ttgatcgaag tatctccttt tttgacagct aattggatcc cgctatcaaa gtaagaatca
    16441 gaaaaatcat agcttttctt tcgttcatct gttacagtca ttccggcaat cattccgtct
    16501 gcttgtcctg attccaaagc ttgcaaagca gcagagaaac cacggtagtc cattcggatg
    16561 ttaaatcctt gcagtttggc gatgttttcc atcaatttta catcgatgcc ttcgtactcg
    16621 ccctttgcgt tttgaaattc aaatggagca aaagcagagt cactggcaat tacgtatacg
    16681 tcttttttgg gctctatttt ttgcattgtc tcgcttgtgc ttgactctgc cgttgtagtg
    16741 ttgtcagctt gtgcaacatg accaaacgca agtgtcacaa gtcctgtcat taagaaaaca
    16801 aatgagtgaa ataaatgctt tcttttcata atcaacctcc taaatttcca atattttatt
    16861 attataggcg aaaagtgctg aatcagacaa gactgtaagc tcgaaaaaat gaaaaaaatg
    16921 cgagtttcta acattttatg ttataaaaca taacatgtat aataagataa aaaagtggcg
    16981 aaagtatgtt cggtgtggta taatttttta gtaaggaatg cctttgcttt ccttttcttt
    17041 ttattggtcg taaaatgaaa aggaatgaat gaaaaggagg acgaagaatg attgagagag
    17101 atacctcccg acactttgag cttgtctcga aataccaacc ggctggtgat cagcctgaag
    17161 cgattaacca attagtggat ggcgtagtcg gcgggaaaaa agcacaaatc ttattaggtg
    17221 cgactggaac agggaaaaca tatacgattt ccaatcttat tgagaaagtg aataaaccaa
    17281 cactgattat tgcccataac aaaacattgg ctggtcagct gtacggggaa ttcaaggaat
    17341 ttttccctaa caatgctgtt gaatattttg tttcttatta tgattattat cagcctgaag
    17401 cttatgtgcc ttcaagcgat acgtatatcg aaaaagattc aagtgtaaat gatgagatcg
    17461 acaaattacg acattcggct actagttcat tattagaaag aaatgatgtg atcgtcattg
    17521 catccgtttc atgtattttt ggattaggct cgccttttga gtaccaaaaa caagtagttt
    17581 cgattcgaca gggagcagaa ctagatcgca atcagttgat tcgtgactta gtcagtatcc
    17641 aattcgaaag aaatgatata gattttcagc gcggtcgttt tcgagtgcgc ggtgatgtcg
    17701 tggagatttt tccggcttca agagatgaac gtgccttacg tgtggagttt tttggagatg
    17761 aggtcgaacg tatccgagaa gtcaatgcac tgacaggtga agttttagga gaaacggaac
    17821 acgtagcaat cttcccggcg actcactttg tgacgaatga tgaacatatg gagcatgccg
    17881 tagcgaatat caaagcggaa ttagaacagc gtttaactgt cttgcgaaat gaaaacaaac
    17941 ttctggaagc tcaacgttta gaacagcgaa ccaattacga tattgaaatg atgttagaaa
    18001 tgggctacac gtcgggaatt gaaaattatt ctcggcatat ggacggacgt aaagaaggtg
    18061 aaccgcctta tacgctattg gatttctttc ctgaagattt tttgatcgtg gcggacgaat
    18121 cgcacgtaac catgcctcaa atcagaggaa tgtataatgg tgaccgagcg agaaaacaga
    18181 tgctagtaga ttacggtttc cgtttgccat ctgctttaga caatcggcca cttcggttag
    18241 aagagtttga aaaacatgtc aatcagatca tttatgtctc tgcgacgcca ggaccatatg
    18301 aacatgaaca aacagatacc gttatccaac aaatcatccg tccgacaggg ctgcttgacc
    18361 cagtgatcga agttcgtcca atcatgggac aaatcgatga tctagtaggc gaaataaatg
    18421 aacgagtcga aaaagaccag cgggtgtttg taacgacatt gacgaaaaaa atggcagaag
    18481 acctcacaga ttatttcaaa gaattaggga tcaaagtcaa atatttgcat agtgatatca
    18541 aaacgctgga acgaacagaa atcattcgag atcttcgatt aggtgaattt gatgtgttag
    18601 ttggaatcaa tttgcttcgt gaaggattag acgtacctga agtttccctt gttgctatct
    18661 tggatgcgga taaagaaggc tttttacgta gtgaacgttc cttagtccaa acgattggac
    18721 gagctgctcg gaatgaagaa ggtaaagtaa tcatgtacgc agacaaagta acagattcta
    18781 tgcgtctagc gatggatgaa acgtcaagac gtcgtacgat tcagcagaag tacaatgaag
    18841 aacatgggat cgttccaaaa acgatcatta aagaaatccg agatttgatt tctattacga
    18901 aagaatcgga agatgataca aaagaagcgg tacaagtctc gtacgaagaa atgacgaagg
    18961 aagaaaaaga cacgttattg atgaaattag aaaaagaaat gaaagatgcg gcaaaagctt
    19021 tggattttga aacagccgcg aatgtgcgag atatgatttt agaattaaaa gcttcaaagt
    19081 aggaggacaa catggctaac gataaaatta cgattcatgg tgcacgtgcc cataacttga
    19141 aaaatataga tgtaacgatt ccacgagata aattcgtggt cgttacaggt ttgtccggtt
    19201 ctggaaaaag ttccctagca tttgatacgc tgtacgctga agggcagcgg agatacgtag
    19261 agagcctttc tgcttatgct cgtcagtttt taggacaaat ggataagccg gacgtagata
    19321 gcatcgacgg attgagtccg gcgatttcta ttgatcagaa aacaacaagt aaaaatcctc
    19381 ggtcgacagt aggtactgtg acggaaatca atgactattt acgcttgttg tttgcacgtg
    19441 taggacatcc gatttgtccc aacgatcata tcgagattac cagtcaatca gtagatcaaa
    19501 tggcagatca agtaatggct ttgcctgagc gcacaaagat ccaagtgttg gcaccgatcg
    19561 tggtaaagaa aaaaggacaa cataaaaaaa tattcgaacg aatccaaaaa gagggatacg
    19621 tccgcgttcg agtcgatggt gagatctatg atttaagtga agtgcctgag ctggagaaaa
    19681 acaaaaaaca tgatatcgcg atcgtcatcg accggatcat tgtgaaagaa gggattcgtt
    19741 ctcgcctatt tgattcttta gaggcggccc tgcgattagc agacggctat gctctggttg
    19801 acgtgatcgg tgaagaagaa atgttgttta gcgaacacta tgcctgtcct tattgcggat
    19861 ttactgttgg cgaactagaa ccaagactgt tctcattcaa tgcgcctttt ggagcttgtc
    19921 cagactgtga tggtttaggt gtcaaattag aagtcgatca agatttagtg attccagata
    19981 gaacgaagac acttagtcaa ggtgctatcg ttccatggaa tccaatcagc tctcagtatt
    20041 atcctcaaat gttagcgcag gcttgtgaaa gtttcggtat cgatttagat acaccattcg
    20101 aagaattacc ggaagagcat caggagatca tcttgaatgg gacagatgat cttttccatt
    20161 tccattatga aaatgatttt ggtggcgttc gcgatgtaga aacgactttc gaaggggtat
    20221 tgaagaatat cgagcgtcgt tatcatgata cgaacagtga tttcacgcgt gagcaaatgc
    20281 gtctttatat gacagaatta acttgtcaga catgtaaagg ttatcgattg aatccccaag
    20341 ctctatctgt tcaaatcaat ggaacgaata tcgggcaaac aaatgagttg tctattcaaa
    20401 aagcagtaga tttcttctca aacttaacgt tatctgaaca agagaaagta attgccaaac
    20461 cgattttaaa agaagtaaat gacagacttt cattcttgga aaatgtggga ctagactatc
    20521 taactttgag tcgcgcttcc ggaacattat ctgggggaga agcgcagcga atcagattgg
    20581 ctacacaaat tggatcgaat ctttctggag ttttgtatat tttagatgaa ccatcgatcg
    20641 gattgcatca acgcgacaac gatcgactga ttggctcatt aaagaaaatg cgtgatcttg
    20701 gcaacaccct cgttgtagtc gaacatgatg aagatacgat gtgggcagca gattatttga
    20761 ttgacgtcgg acctggggcc ggagaacaag gcggacaaat cgtggctgca ggcactcctg
    20821 aagaagtagc taatgatgaa aattctttga cagggaaata tctttcaggg aaaaaatcaa
    20881 tccctgtacc aaaagaacgc cgtaaaggta atgggaaagc aatcaagatc actggtgctt
    20941 cagaaaacaa tctgaaaaat attagtgttg aatttccatt aggagaattt gtagcagtca
    21001 caggtgtgtc tggttctgga aagagtacat tggtcaatag tatcttaaag aaatcgttag
    21061 cgcaaaaatt aaataagaat tctgctaagc caggtaaatt caagacaatt tccggctacg
    21121 aaagtatcga aaagatcatc gatatcgatc aaagcccaat cggccggacg ccgagaagta
    21181 atccagcgac ttatacaagt gtatttgatg atatccgtgg gttatttgct caaacgaacg
    21241 aggcaaaaat gcggggttat aagaaagggc gttttagttt caacgtaaaa ggcggtcgtt
    21301 gtgaagcttg tcgcggggat ggaattatta agatcgaaat gcactttttg cctgatgtct
    21361 atgttccttg tgaagtatgt catggtaaac gatataattc tgaaacatta gaagtgcatt
    21421 acaaaggaaa aagcattgct gatattttgg aaatgacagt agaggatgct gtagaattct
    21481 tcaagcacat tccaaagatt catcgcaaac tgcaaacgat tgttgatgtt ggcttaggtt
    21541 atgtgacgat ggggcaacca gcaacgacat tgtccggtgg tgaggcacaa cggatgaaac
    21601 ttgccagtga attgcacaaa atctctaatg gaaagaattt ctatatacta gatgaaccaa
    21661 cgacaggact tcatagcgat gacatcgccc gcttgttgca tgtattacaa agattagtag
    21721 atgctggtaa cacagtttta gtgattgaac acaatctaga tgtaatcaaa acagcagatt
    21781 atatcattga tttaggacca gaaggtggag aaggtggagg aacgatcctt gcgactggaa
    21841 caccagaaga aatcattaac gtaaaagaaa gttatacagg tcactatttg aaaaaaataa
    21901 tggtataaag aggatagata gctgagatag ttaaaaaaac ataaaaaaat gaatttttgc
    21961 ttgttttatt aatatcagtg ttctagaatc attacatggt agttctttct acactgattg
    22021 gtatagataa aaacttccta taagttcaat ccgttcaaaa aagaattgag caatcggagg
    22081 actttccttt gattgctttt ttctttatgg tatgatattc cttgtgtagt tggaaaagaa
    22141 aaacaagaga ttatgagtaa gtgagagata atgatgaaca gtattgaaaa tgaagaattt
    22201 atccctatat tattaggaag cgacatgaac gtttatggta tggcacgttc ttttaatgaa
    22261 gcatacggca aaatctgcca agcatatgct tcggatcagt tagcccctac ccgctacagt
    22321 aaaattgtca atgtagaagt tattccagga tttgataaag accctgtatt tatcgagacg
    22381 atgcttcgtt tggcaaaaga aagatattct gataagagta aaaaatatct tttgattgct
    22441 tgtggtgatg gatatgcaga attgatctcc caacataaac aagagctgtc agaatatttt
    22501 atctgtccat atattgatta ttctttattt gaaaggctga tcaataaagt aagcttttat
    22561 gaagtttgtg aagaatatga tcttccgtat cctaaaacat tgatcgtcag agaagaaatg
    22621 ttagtaaatg gacatttgga acaggaattg ccttttgaat tcccagttgc tttgaaacct
    22681 gcaaacagtg tggagtatct ttctgtccaa tttgaaggaa gaaaaaaagc ttttatttta
    22741 gagactagag aagagttcga tttaatttta ggccggatat acgaagccgg ttataaaagt
    22801 gaaatgattg tacaagattt tatcccgggt gatgatagta atatgcgtgt gctaaatgcg
    22861 tatgtagatg aagatcatca agttcggatg atgtgccttg gtcatccact attagaagat
    22921 cctacaccag catcgattgg taattacgtt gtgatcatgc cagattataa cgaaaaaatc
    22981 tatcaaacca ttaaggcatt tttggaaaaa atcgaatata caggctttgc caatttcgat
    23041 atgaagtatg atcctagaga tggagaatat aaattatttg aaatcaattt gagacaaggt
    23101 cgtagcagtt tctttgtgac attgaacggc ttgaatctgg ctcgttttgt cacagaagat
    23161 cgagtgttca acaaaccctt tgttgaaacg acctatggaa cgaatcaatc agataaagca
    23221 agattatgga tgggtgtgcc caaaaaaatc tttttagaat atgctcggga aaatgaagac
    23281 aaaaaactag ctgagcaaat gatcaaagaa aatcgttacg gtactactgt attttatgaa
    23341 aaagaccgat caatcaagcg ctggttgttg atgaaatata tgttccataa ctatattcca
    23401 agattcaaaa agtattttca tgtgaaagaa ggctagttca tggagaattt tttcagtatt
    23461 ttaggcggaa tgggcacgat ggcgacagaa agttttgttc gcttgatcaa ccaccgaacg
    23521 aaagctacaa aagatcaaga atatttgaat tatgtcttat tcaatcatgc aacagttcct
    23581 gatcgtacag cttatatttt agatcgatca gaagaaaatc caatgccgtt tctgctggat
    23641 gatattgaga aacaaaattt attgcgacca aacttcattg tgttgacttg taacaccgca
    23701 cactactttt ttgaagagtt acaagcggca acggatattc ctatcttgca tatgccaaga
    23761 gaagcagcaa atgaacttgt ccgtcagcat acgacaggga gagtagcgat tctaggaaca
    23821 gaaggaagta tgaaagctgg aatctatgaa cgcgaagtca aaaatcttgg tttcgaaaca
    23881 gtgattcctg atactgcgct tcaagaaaaa atcaattacc tgatctatca tgagatcaag
    23941 gaatcggatt atttgaatca agagctctat tacgaaatct tagaggaagc ggtagagcgc
    24001 ctaaactgtg aaaaagtcat cctaggttgc acagaattat ctttgatgca tgaatttgct
    24061 gaagataatc attacccagt gatcgatgct caatctattt tagcggatcg aacgatcgaa
    24121 cgtgcattag ctgaaagaag cgaggcattg gatacagcat cggaaaagta aaaaaattgg
    24181 atttggggca aatatcctaa aagatatttg gtccaaatct ttttgtaaaa gaaaaagaaa
    24241 actggtaatg atacgcccgg gatgatataa ttttattatg cacaatgtga gaggggttcg
    24301 taaatatgac agataatttg caattagtca tcataacagg tatgagtggt gcagggaaaa
    24361 cagtagctat ccaaagtttt gaagatatgg gctatttttg tatcgataat atgccgcctc
    24421 gattgattcc aaaattctgg gaattgatca aagaatcagg taaagtcaca aaaatggctt
    24481 taggagtgga tttgcgttct cgttccttct ttgaagaaat ccaaaacatg ctgatcgaaa
    24541 tcgaaaatac gaacttcatc gacacttcta tcttattttt agatgcttca gacgaagaac
    24601 tagtggctcg ctacaaagaa acaagacgag cacatccaat ggcgatggac ggtttgatca
    24661 ctgaagggat acgtaaagaa cgggcgatac tagacgactt gaaagcccaa gcttccgtga
    24721 tcattgatac gacaacattg acaccacgac aattacgtga aaaaatcaat gagtcattca
    24781 aatcaaaggg agaccaagga tttcggatcg aatttgtatc atttggtttt aaatacgggt
    24841 tgccgatcga ttcggatatt gtgatggatg tgcgtttttt gcccaaccct cattatatcc
    24901 cggaactaag accattgacc ggaaaagatc agccagtcta tgattatgtg atgtcctttg
    24961 atgaaacgca atcattctac cataaatttt tggatcttct ggaaactgta ttgcctggat
    25021 acattaaaga aggaaaaagc agcttgacag ttgcaatcgg ctgtacaggc ggtcaacacc
    25081 gttctgtggc attgactgaa cgtttggcaa atgctttagg gaaaaactat aaagtcaatg
    25141 tgacacatcg ggacaaggat aaaaggaaag agacggtgaa ccggtcgtga aaatgaaaac
    25201 ctaccggata agaaaaccaa agatcgtagt ggtcggcggt ggcactggtc tgccagttat
    25261 cctgaaaagt ttacgaaatc aaggagcaga tatcacagca gtagtgactg ttgcagatga
    25321 tggtggaagc agcggtgcaa tcagagaatc gatcgctatg gctcctcctg gtgacttgag
    25381 aaatgtctta gtggcgttat cggatatgcc acaattctat gaagatattt tccaataccg
    25441 tttcaaaaag gaagatcagt ttttagccaa tcatacgatc ggtaatctga tcattgccgc
    25501 agtttccgag atgcggggaa gcacttatga ggcgattcaa ttattagcaa aaatgatgca
    25561 tgtagatgga catgtttatc cttcttcaga aactcctttg accttgcatg ctgtttttaa
    25621 agacggaacg actgcagtag gagaatctaa aatcgcgatc aaccgtaaaa ccattgaccg
    25681 tgtgtatgtc tgcaacacaa atgataaaag tgaagccaaa gcggctcgaa aagtcgtttc
    25741 agcaattatg gacgccgaca tggtcgtttt gggacccgga agtttattca ccagtatcct
    25801 tccaaattta gtgataccag aaatcggcga agcaatgctc aagacaactg ctgaaaccgt
    25861 ctatatctgt aatatcatga cccaaaaagg ggaaacggaa catttcacag atgccgatca
    25921 tatacgtgtt ttacacaagc atttgaatca gccttttatc gatacagtat tggtcaatac
    25981 ggaaaaagtg cctgaagatt atatggaccc agagatctat gatgagtatc tagtacaagt
    26041 cgcacacgac ttcaacggat tgagaaatga aggatgtcga gtgatttcca ccgacttttt
    26101 agaattgaaa gatggtggtg tcttccacga tggagacaaa gtagtagaag aattgttccg
    26161 tttagttttc ggttcaaaat attaagcaat ttattgttgg agaaaggagg agaataggat
    26221 gtcatttgct gcagatgtga agaaagaact aactggtttg gaagttcatc gagaacatgc
    26281 gaaagcggaa ttagctgctt tgctgcgaat gaacggctct ttaggtattg tgaaccagca
    26341 gtttattttg aacgtccaaa cagaaaatgc tgcaattgcc agacgtatct attctctttt
    26401 gaaagatcat tatcaggtac gaagtgagct actcgttcgt aaaaaaatga aattaaaaaa
    26461 gaacaatgtc tatatcgtcc ggttgaagca aggcacaaaa gatgtgttga tggatcttga
    26521 tatcatggat ggtatgatgt tcaatggaca cgtttcggac gagattatgg gaaattcgca
    26581 aaaaatgcgt tcttacttac gtggtgcttt tatggcctca ggttcagtca ataatccgga
    26641 aacgagtcgt tatcatttgg aaatattttc tatttatgaa cagcataacc aagacatttg
    26701 cgatatgtta aattattacg gtctacatgc tcgaacgctt gaacggcgca atggctatat
    26761 ttcgtattta aaaggagcag aaaaaattgc tgatttctta acattgattg gtgcaaccaa
    26821 ctcaatgctc cgatttgaag atgttcgaat cgtacgggat atgagaaatt cggtcaatcg
    26881 tctagtcaat tgtgagacag caaatctgaa caagacgatt gatgcggctt ctaaacaaat
    26941 cgaaaacatc gaattgatcg aagcaaaggt cggtctacat gcccttcctg aaaaacttca
    27001 ggaaatcgca gaacttcggc ttcaacatcc agaggtcagc ttgaaagaat taggggaaat
    27061 gattccctca ggtgcaatat caaaatcggg aattaatcac cgaattcgca aaataaatga
    27121 atttgcggaa aaactgcgtg aagaagcagt ttaatccaaa gaaaaaactg atacatgaag
    27181 caggagatgc gaatgtatca gtttttttta aaagctatac ttgcttttct tccgtcaaac
    27241 tataattcca actttactgg agtaacataa tgttgaaagg cttctattgt tttttaatac
    27301 aatcgtataa aaagcgggga gacaactgaa tgaagatttt agttttatac ataaactttt
    27361 gcttaatata gaagtcctga tatagatagg atcaagtatt tatctataac tggagattaa
    27421 ttaaaaactg gaaggaactg ctcgatcaac cttgagaact gtttttctta cttctggtca
    27481 agattctcgt ggttggtgga taaggatggt tgataagttc attggattag ctagtcgaaa
    27541 acaaccaggt gtaattaatg tagaagtttt aacaagggga tggagtgatt tattcagtga
    27601 taatcataag ttcataaata gtaattggga tgtatggttg gtatacgtta tacctgaact
    27661 tgaactatca agatttggtt tagaatttga gaatcgatgt ttataaaggg agggcaaaaa
    27721 atgtgctttt ttacaacttt tactatcatt atgattgcag tactttttat ttttctagat
    27781 atagcaaagc gaaatacagc atttttatta tatcgggttt tacttcgagc aggtctcata
    27841 acatttatat cgatcgttgg attttttcta ttcacagtta ttgtatttat ttggagaact
    27901 acagcaccac cattgccaga gattacatat ggagaatttc cgtttagtct tgaatatgaa
    27961 atagatgagg aaagaatttt gattgaagat acggtgattg cagaatttat aggaagtttt
    28021 agagggaatg tgacaactca acctagacga agttggagta taaaactttt aaataatagt
    28081 ggagagttga aagcatttca ttatgaattc ttaataatag aaagtgaaga tgtaacaatc
    28141 actttaagta gtggctctgc tggatatttt atgaatgatg gtggaagcaa gccacagctc
    28201 acagtccgtg atcgtattgc aggttttatg catttttctc actatgactt agaagaagct
    28261 cgtaaaatac ttgcagaata tgggatcaca ttaatcaatt gggaatatgc gccaccgata
    28321 agaaattttt tcaatgatta ttattagtct tataaaaaac agaatgtaaa atttatgtgc
    28381 gcgagtattt agttttccat tttttgtttg atagatatat agcattgttg aagcatggga
    28441 tagtggtgcc aattttatca atgaggttgg tcaggcagtt aacataattg gtgatgctat
    28501 aaatccattt aattggaatt ggaggaatta ggtgtggaaa cagtgagatt atggatattc
    28561 atgaaaaatt ttcgttcggc tttgagatat gttattctgg aatcaaaatc aggttattat
    28621 ctgattgaca cagatcacta tactttttgg ggaggctacc tttttccgat ttttaattgg
    28681 ataatccccc ataaggttat gaaaattaac ttgcctgcag aagaaataaa tagattaata
    28741 ctcaacaaag atttacaaag gaaaagagag aaagaacatt ctaatgttgc ttggataggt
    28801 ccagcatttg cagtagtgac ttcttcaatt gtcggtccta tgctagagag tatttatagt
    28861 gatttttcta ttggaatacg ttatttattt gttactttaa gtatagctgt tcttttgtgc
    28921 ataaagggtt atgttagcaa gaagaataaa gatattttaa cactaatcgg tgtaaacaat
    28981 ttatctagta ctaaaattat actgtttcct gaatctataa aagaaggatc aaggttgttg
    29041 ataattttta taatgcttat actgttttct gttttatttg gggtgatgtt tatag
//
LOCUS       DBBGSP010000038        28018 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000038 DBBGSP010000000
VERSION     DBBGSP010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28018
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.038"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(25..606)
                     /locus_tag="ACIZE9_001914"
     CDS             complement(25..606)
                     /locus_tag="ACIZE9_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6093766.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(789..1415)
                     /locus_tag="ACIZE9_001915"
     CDS             complement(789..1415)
                     /locus_tag="ACIZE9_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HGC6093767.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(1437..2768)
                     /locus_tag="ACIZE9_001916"
     CDS             complement(1437..2768)
                     /locus_tag="ACIZE9_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGC6093768.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(2923..3324)
                     /locus_tag="ACIZE9_001917"
     CDS             complement(2923..3324)
                     /locus_tag="ACIZE9_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HGC6093769.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(3410..3616)
                     /locus_tag="ACIZE9_001918"
     CDS             complement(3410..3616)
                     /locus_tag="ACIZE9_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093770.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(3711..5213)
                     /locus_tag="ACIZE9_001919"
     CDS             complement(3711..5213)
                     /locus_tag="ACIZE9_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HGC6093771.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(5231..5686)
                     /gene="argR"
                     /locus_tag="ACIZE9_001920"
     CDS             complement(5231..5686)
                     /gene="argR"
                     /locus_tag="ACIZE9_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGC6093772.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(5784..6401)
                     /locus_tag="ACIZE9_001921"
     CDS             complement(5784..6401)
                     /locus_tag="ACIZE9_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGC6093773.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            6622..7995
                     /locus_tag="ACIZE9_001922"
     CDS             6622..7995
                     /locus_tag="ACIZE9_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6093774.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            8070..9182
                     /locus_tag="ACIZE9_001923"
     CDS             8070..9182
                     /locus_tag="ACIZE9_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC6093775.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(9254..10891)
                     /locus_tag="ACIZE9_001924"
     CDS             complement(9254..10891)
                     /locus_tag="ACIZE9_001924"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HGC6093776.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(11059..11667)
                     /locus_tag="ACIZE9_001925"
     CDS             complement(11059..11667)
                     /locus_tag="ACIZE9_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGC6093777.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(12051..13202)
                     /gene="queG"
                     /locus_tag="ACIZE9_001926"
     CDS             complement(12051..13202)
                     /gene="queG"
                     /locus_tag="ACIZE9_001926"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HGC6093778.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(13221..13973)
                     /locus_tag="ACIZE9_001927"
     CDS             complement(13221..13973)
                     /locus_tag="ACIZE9_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093779.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(14114..15064)
                     /locus_tag="ACIZE9_001928"
     CDS             complement(14114..15064)
                     /locus_tag="ACIZE9_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HGC6093780.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(15065..15904)
                     /locus_tag="ACIZE9_001929"
     CDS             complement(15065..15904)
                     /locus_tag="ACIZE9_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGC6093781.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(15901..16647)
                     /locus_tag="ACIZE9_001930"
     CDS             complement(15901..16647)
                     /locus_tag="ACIZE9_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGC6093782.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            16885..18255
                     /locus_tag="ACIZE9_001931"
     CDS             16885..18255
                     /locus_tag="ACIZE9_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6093783.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(18310..19206)
                     /locus_tag="ACIZE9_001932"
     CDS             complement(18310..19206)
                     /locus_tag="ACIZE9_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGC6093784.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(19320..19490)
                     /locus_tag="ACIZE9_001933"
     CDS             complement(19320..19490)
                     /locus_tag="ACIZE9_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093785.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(19487..20164)
                     /locus_tag="ACIZE9_001934"
     CDS             complement(19487..20164)
                     /locus_tag="ACIZE9_001934"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGC6093786.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(20255..21160)
                     /locus_tag="ACIZE9_001935"
     CDS             complement(20255..21160)
                     /locus_tag="ACIZE9_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HGC6093787.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            21335..22759
                     /locus_tag="ACIZE9_001936"
     CDS             21335..22759
                     /locus_tag="ACIZE9_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HGC6093788.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            22805..23836
                     /locus_tag="ACIZE9_001937"
     CDS             22805..23836
                     /locus_tag="ACIZE9_001937"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGC6093789.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            23843..25030
                     /locus_tag="ACIZE9_001938"
     CDS             23843..25030
                     /locus_tag="ACIZE9_001938"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGC6093790.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            25186..26568
                     /locus_tag="ACIZE9_001939"
     CDS             25186..26568
                     /locus_tag="ACIZE9_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HGC6093791.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            26605..26925
                     /locus_tag="ACIZE9_001940"
     CDS             26605..26925
                     /locus_tag="ACIZE9_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093792.1"
                     /translation="MGDCFCDGRTSQRYQKNEEEARKQPLPKQQMTLQEIDSILTEAF
                     LSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYFMIDHQPILWEDVRYIELKETKK
                     WFVT"
     gene            complement(27125..27793)
                     /locus_tag="ACIZE9_001941"
     CDS             complement(27125..27793)
                     /locus_tag="ACIZE9_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGC6093793.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT         7796 a         5735 c         5147 g         9340 t
ORIGIN      
        1 cacttctgtc acaacctcta attattaaag aaccttttgc gaagttaaca atctttcttt
       61 gatcaattga aaattctgcc taagtagtga tagatcctgt gtgactttca acaataagat
      121 acttccctgg atttcagcaa tcaacgcttt ggcttgacgg tctgcttctt catcggacag
      181 tttttcttca gaaagtgcca ggatattttg tttcgtatac ttgacccatt gattgactaa
      241 ttctagtagc aacagacggt attcttcatc cactgtactc aactcaataa tcaaattacc
      301 tacaggacag ccatgataag tgatctgtgt ctcatgatca gcgaaaatcc agtccaacat
      361 ttcttctaat gcttcttctg gctgttttcc agcatttaag atgtcttcga acaattctgt
      421 ctgccatacg tccatatgcg catggatcac cgctagacaa acttcttttt ttgaagaaaa
      481 gtaataataa aattgacctt ttcctgtatc agaagctgct agaatatctc ggattgacgt
      541 ttcatgatag ccttttttat aaataagatc tttggtcgct tccaagatct tttcctttgt
      601 tttcaatgat attctccttt ttcatttctc atagtcctat attatacagt aaattcatca
      661 ttttttcttc ttaatcgttt aaaaaagact gtgccaaatt atctgacaca gccctcacta
      721 taaaactgtt ctcatatagc tagatgttca ttgattcaag aactgcgagg acaaaagcaa
      781 ttcctatctt atgatagttg ctctaatact tcctctgttg tcatcacttg atctgcaata
      841 aagccaaagt tcgtcaacgc tgcatccatt gcttcttggc caggagcacc aattgcatct
      901 gtcgctacca caacattgaa tccactctct accaattcac gcatatggga atcgctacac
      961 aagtttccgt tcattccacc aagaattact gtgtcgattc cattttttct caattggagc
     1021 gccaaatcat tgctttctgg tccaaagatt ttatgaggag agctgatgat cgtattttca
     1081 tccaaataag gtttcaattc ttcgataaaa tcggctcctg aaccttcttc cactgattca
     1141 tattgacttt ttctagcaaa catctgctgc tcaagcatca tatgttctcc tgcaccgcca
     1201 aattgccatt tatggtcatg tgggtaaaaa taatgaggag aaataaagag tttgtatcct
     1261 ttttcttttg cttgttttac catttcaatc atattttcga tcgtattgta tttttctaag
     1321 atatcttttg tcaaaccaaa gccaccgcct gctggtttca agaactcgac ttgcgggtca
     1381 gtgagaacta ctgctgtatt tttattattg aacatggtgg attctccatt cgttatttat
     1441 tttaatacat catttagagc ttcactcatt gtcggatgag aatagatttg atctctcaat
     1501 aacgtataag gaagttttcc attcatagct agcgaaatca agttgatgac ttcatgagaa
     1561 tcttccgcat agatacttgc ccctagaatc aagtcagttt cagggtcgac taaaactttg
     1621 aatacacctt taggatcttc taatacttgt gctttaggga caccgcttgt catatacttg
     1681 aataatttgt aattgacgcc ttgtgctttg gcttgttttt ctgttaaacc tacattggat
     1741 aaagtcggag tgataaatac actgtaaggc acagctttcc ggttattcgt tgttcgttta
     1801 ttctcgccct tcaactgatc cataatgatt cgataatcat ctagagagat ataagtgaac
     1861 tgcaatccgc ctttgacgtc tccaatcgcc caaatgttgt ctgcatctgt acgaaggtat
     1921 tcatccacag cgattgctcc gcgatctgtt agtttaacat ctgtattttc taatccaagt
     1981 gatgctgtac ttggttttct tccagttgca gccaaaactt ttgacgcttg gattgttact
     2041 tcttggccat cttctgtaaa ggtgacggca gctgttgatt cttggtctgc tacttgatct
     2101 acagatacac ctagatggaa ttcgattccc gcatttgtca tgtcttctaa aatcatttgc
     2161 gcgatatctt catcttcacg tggaagaaat tcagaatggg catcaagaac gacaacttta
     2221 gatccgtatt cattgaacat tgatgcaaat tccaagccaa tatatccagc cccgatgatc
     2281 actaattttt ccggtaattg ttcctgatcc atcgcttgcg tagaatcaat caagtagcga
     2341 cttgtattca atcctttgat tggtaaaatg attggttcag aaccagtatt gatgaaaatc
     2401 cgttcgcctt caacaatcac tttttcacca ttattcgtca cttcgatttg atggttagaa
     2461 agaaaacgtg ctgtaccgtc catcactgtc ccagttgcct catcgctgat catatgataa
     2521 tttttggcgc gaagcatgcc cgtcaatttt tctttccgag caacagcctc tgtaaagtcg
     2581 attcctcttt ctccattgaa aatcaatgat ttagaaggaa tacagccgat gttgatacat
     2641 gttccgccat acatacgtgt tgacttttca acgactaaaa ccgattcacc ttttgaagct
     2701 aacgccttcg ctaaagtctt accgcccttt ccaaaaccga tcacaatatt ttgatatttt
     2761 tccatcattt ttccctcgct tcttttttac ctaccgattg gtacaaaaat atgataaccg
     2821 ataattgtct attctccaaa tcatctgctt tatttgtcaa aaaaaaccag acaaaaagcg
     2881 gtcctttcac gtttttagtc tggttcgatt tcctttattc ttctaaacaa tcgttacttc
     2941 tacatcgata tttcctctag ttgctttgga gtaagggcag aattcatgcg catcttctgc
     3001 aattttttgg gcttcttctt cgctgatgcc atcgatatgc acttctaata ctacaccgat
     3061 ctgatagccg ccatcatcta aattataaag agagacacgt gcttttactg tggactctgc
     3121 tgtcattcct gcttctttga tcatatgttg taccgcccca ttgaaacaag aagcataacc
     3181 tgctgcaaat aattgttctg gatttgttcc ttctgcatgg attcctggag gagtgatttt
     3241 catatgcatc gagccatttg gtgcctcgac ttctccattg cgcccgccat ggttgatcat
     3301 tgctgtttcg tatgcttttt tcattgtact gctcctttcg attgaccatt tgctacttgg
     3361 ctataattat agtgtatgac aagtaaggcg ctttctacaa aaattctgct tattcgaata
     3421 ccagaatgcc gtcttctact atttttccaa aaaacaaaaa aatactactc gtgaacaaca
     3481 gcgtcatatt tgttccaaaa taaatagcaa tcttttctac ataatctttt atatgattga
     3541 ttttaagata catatatacc agaaagttga ccccataaac caatactgtt aaaaaaataa
     3601 ccatattcgt taccattttt tcctcctttt gctggtctcc ctaccagcac tcgatttaac
     3661 cataccactt tttttgccgt ccaagcaact agcctttcaa aaagactggt ttattctgct
     3721 gttaatgatt caagatcaga aaaatgtccg aataattttg ctaattttac taacgccaac
     3781 ttgttctttc cgaattcatc attttctatc tgtaatacta gtaacggctc atgtaagctt
     3841 aaacggatca aaaaccagcc gtttccgtat ggctcttcta gatcatatcg aataccttct
     3901 tcattttccg ggtcgaagtt catccctttt tcttcttcca acagtcgctt catttcttct
     3961 aatatcttgt ttccttgttc gcgtggttca tcgctgaaca attttaatcg gatttcttgt
     4021 acttctacgg gctgtttcaa ctctttgatt tgttcatcta atgtgatacc ttttcttttt
     4081 aattctggca aaagcatcag gatctttgcg atgacatatg caccatcatc cagaaaatag
     4141 ttttccttga atgcagcgtg tccgcttgtt tcgatggcta gctgtgtatc tttcccaaga
     4201 cggttaagtt ctaatgcttt attgattaca tttcgatagc cggaaatata acgaacttgg
     4261 atgcctcctt tttcttcaat gaatctttgt agatgagaag aagtagggga attcgtcacg
     4321 attcttgttc ctggatgctc ttttaatacg attgtactta atactgcgat caaattattt
     4381 cgattgatca ctgttccaga agcactgaca actgcagaac gatccacatc tgtatcgaaa
     4441 atgatcccaa gatctgcttc atttgctaaa acagcctgct tgatactttc catcgcttct
     4501 ttattatcag gatttgggat atgattagga aatcggccat ctggttccaa aaattgggaa
     4561 cctgttgaat ccgcacctaa gctattcaat actttttcag caaagaatcc accagcacca
     4621 tttccggcat caacaatgat tttccaacca tttagtggtt tgctttctag tgttccaatc
     4681 ccctttttaa tttttgtgac taaatcttgc gcataaggtg tcaaaaggtc tgctttttct
     4741 acgcttccag tttgttcgct ttttattttt tgctgctgtg ataggataaa agcaatatct
     4801 tctttttctg ctcctccttc tgaggtaaag aattttattc cattataata atagggaaga
     4861 tggctagcag tcagcataac cgcagcatcg cacgagaact gttcaaattg agtggacata
     4921 aacatagcag gcgtagtagc taattcgaaa tcgatgacat gtatcccttg ttctttcaga
     4981 ctttggatca acgcctcttt cagtgctggt ccgcttatcc tactgtcatg accaatccca
     5041 atcgtccatt ttttatttgg atcggttgat ttcttctttt tctttatcca gtttgctagt
     5101 ccccagccga tcttttttac catgtctgtc gtcaagttta cttcatatcc ttcaactggt
     5161 aatgcgattc ctcgaatatc cgatccattt tgcagcgctt tcatatcttt catataaaag
     5221 tcctcctcat ttattccctc attttttcca gcttttctgc aaatcgctgt gcttcttctt
     5281 ctgagcggca aataataatg aatgtatcta caccggccat cgttccgaca acttcagggt
     5341 aagccacttc atctagccaa ttcgttacca catcggcacc atttcgttca gtcaatacga
     5401 taaccatgaa ctgaacagac tggatacgca aaacctcgcg tctaattgct gtacgcaaac
     5461 gttcttcatt taaagaaaca gatggctggt taaataatgt atagcgtact attttgtttt
     5521 cattttgact ttttactaac ttcatttctc gaatgtctcg agaaatcgtt gcttgagtca
     5581 catcggcgcc tgcttcatgc agccgcgcaa gcagctcttc ctgtgtccca ataggttgtt
     5641 ctgtaatgat ctggcggatc agtgcttgtc gctgtttctt tttcatatta gacacctctc
     5701 aatgttgatt atagcaaaag ataagtaata tttcttcata ttttggtatt ttttactttt
     5761 attttttgtt ttcattcagg ttgctaacct ttttctattt taacacgcaa aatcgtcttc
     5821 attttttcag gtgctgattt tcttggatcg ctgatgtaaa tctctttgtg ttctttagaa
     5881 gctctttcat agccttcttt tgcgatgaat gcttctaatt tctcaaacgt tgctggttct
     5941 tcggcatagg gcccgacgtg taagatttgg gcacaaagac cttcttccat ctttttgaat
     6001 actacttgtt ctttcaagtc ttccggaagt ttgctagaac gctgaatggc ttcttgtgct
     6061 atcgcttctg taacaaagtc aggctgtcgg atcatcaatt gataagaaaa atgttctttt
     6121 ttcatcactg gttcatgcaa atacttttct tgcagtcccc attgtccttc cagtggatag
     6181 acagtataca tctgataatc aggaatcagc caattttttt taggcgacat gcgtattgca
     6241 tagctgactg catatagaca ggctactctt cgtttaaagt cttcctgatt cgggtcgccg
     6301 atccctctga tgctaaagaa tgatttttta ggaacctcta gtatttgcgg gctttttttc
     6361 atactatagc tcttgtcttt acgccattca attttttcca tttttcttcc tccgcgaaat
     6421 tccatttagt tatttattat catacctctt tttgagtgac ttggctaatc gtgttgacac
     6481 tatttttcag tttgtgctag aataagtgaa gtaaataaat cgtacagata acacgtttcg
     6541 gcgtgtcgag agagaggcgg tttctatttt tataatagaa atcactctct ttttttacga
     6601 aattttttag aggtgatgta aatgacaaaa caaaaacagc tgcttttagt acctgcagta
     6661 attgcaacag ggatgatgtc ttttgcgggc gtattgatcg agacggccat gaatgtaact
     6721 ttcccaactc ttatcagaca gtttgattta acgactgcac aagtccaatg ggtaacaacg
     6781 atttatcttt tgatgatttc gatcattgtt ccgctgtcta cttatttgaa tcgcaatttt
     6841 agtctcaaaa aactcttttt agcttcaaat ctgcttttct tggcaggtat aatgatcgat
     6901 ttcttctctc ctaccttcat ggtcctattg tttggtcgat tgctccaagg tgcagcgaca
     6961 ggtatcgctc ttccgttgat gttccatatt atcttgacat ttgcccccct caatcgacga
     7021 ggcgcgatga tgggtgtcgg tactttgaca acggccattg ctccagcaat tggccccact
     7081 tatggaggca ttatgacttc acattttaca tggaatcata tcttcctgtt tcttgtgccc
     7141 gttttgtttc tttctttgat tatcggctgg tttgctattc ccgagatggc agtacaaaaa
     7201 agtggttatt tggattggat aagcgtttta ggaatttgtc ttttgtttag tggaagtcta
     7261 acatttttga gtacgttggg aacagtttcc agctggattg ctttaatcat cggcggtatt
     7321 ggctggttcc ttttttacta tcgaagtaaa aaagtggagc atccactgat ccgactgtct
     7381 attctttcaa ataaaacatt ccgcttgttt ttgattggct tcttagttta tcagttttta
     7441 ttacttggtg tatcttttgt cttgccgaat ttccttcaga tcgttcaagg aagtagtcct
     7501 tttgtcgctg gattagcgat gcttcccggc gcagcggttg gtgctttgct ttctcctttt
     7561 tccgggaaaa tgctggatca atatggtccg aagaagccaa tttttgctgg gctgattctt
     7621 tctttgattg gttggctagc attattccta ctcataggac acgcttcagt gggtgtattg
     7681 attgcttgtc atgtgtttta tatgatcggt atcggattat cttacagcaa tatgatgacc
     7741 accggaatga atgcactgaa tgaagaacta caaggagacg ggaacgcaat gttcaatacc
     7801 ttgcagcagt tttctggcgc tgtggctact tcattagtag cggtcattat caattacgtc
     7861 cagcatcata cttcccataa ctatgaagtg tctactacat taggatcaaa agcagcatta
     7921 ggcgtcttgt tgctgttgct tctcgtaagc tttgctcgat tcgcctatta tctgttcttt
     7981 gctaaaaaag cgtagattcc atatacggca ggtgttgcat ctgccgtttt tttgtgtgaa
     8041 aatggttgtt tgtaaaagga ggctttttta tggaaaaaat tgccattatc ggtggcggga
     8101 tcattggtat gaccctagcc agttacttag atacatcaaa attcaatgtt gctttatttg
     8161 atgaagggac aggacaggca actaaagcta gcgctgggat tatctcccct tggttgtcga
     8221 aacgcagaaa caaacaatgg tatcgtctgg ctaaagacgg cgctgctttt ttccctaaac
     8281 ttataaaaga tttccaactt gatcaaacga tttacgcaca atcagggaca cttttgcttc
     8341 gacctgaaaa agatttagct gaattggctg ttcttgccga gaaacgaaaa gaagaagcgc
     8401 cagaaattgg aaacatcgaa tggctttcac ctgaacagac atctcaagca cttccgttat
     8461 tgaaaccagc agtttcactg cgtatcagtg gtggtggtcg tctggatgga aaagcatatt
     8521 tagaacatct tggtcagcgt ttagcacaaa aacaaatgga gcagatccag gcaaaagtca
     8581 ctttgcataa gaagagcgat tcttggctca tcaagggacc gtttggagaa tacacagctg
     8641 atcgtgtaat tttgacacct ggcccggcac ttaagccttt attacaagaa ttaggctatg
     8701 ctgcagatat acgtccgcaa aaagggcagc tcttagcatt tcagacatct tataagatga
     8761 gtcaagactg gcctgttgct atgcttgacg gagaagctga tttcattcct ttcatggatg
     8821 gaaagatcct tttaggtgct acccatgaaa acgatcaagg ctgggatttg gctcctacta
     8881 gcgaagctta taagggattg actaagagta cagaacagtt cttgactgat ccagatcaga
     8941 taaaaaactg gccatacgag ttccgtgtag gtacccgtgc ttatacgtca gatttttccc
     9001 catttttcgg cgtactgcca gatgatccaa gcttactggc tgctagcggt ctaggctctt
     9061 ctggcttgac cacaggtcct tatatcggct atctattagc caacttctta aatactggtc
     9121 attggcctac ggaagattat caaaaggaca tctccaccta tattacgaaa aatccatcat
     9181 agaaaaacag ctttttcaag taaggatccc gagcgatatt gcgcatggat tacttcttga
     9241 aaaagctgtt attttagttc aatttctgaa tcaaattctc caaactttct tttgcttcat
     9301 ctggcaagag atcttttcct atctgagctt caatgaatcg taaacgaata tcaagtcgtt
     9361 gtttcaccag atttttatag gacgtatcct caaaagaaac aggaaaatct ggtataggta
     9421 aatagtggat gtcttcaaat ggaccaaacg acttgaattc tgccgtttgt tgcacgattc
     9481 tttcaacgat tgacaatgtc gtttcaggtt tgattttttt atcatcgaaa tatccagtat
     9541 tcaggacata gcaggctgtt tgctgtttca aaaacaactc tcgaaaagct tgatagtctt
     9601 ccctaagagg atagacacgg aaaggattag caaatggttc aatgactagc tcatctagct
     9661 gtctttttgt agtgatattt tccgcgtctg atcgttttgt tgctaatgtt gcaccaaaag
     9721 acgctgctaa aactgggtca ttgatcttga taattggcgg aagcgaatca tctttcatga
     9781 tccaaaaaac agcatcgatc ttttcgctaa gatgatcgac tcggtcgggt gtcgcataac
     9841 gtgatttgac tgtccgccca tttccgtttc gtatatctcc tgttactagg actttttctc
     9901 ctttacttgt acatgtcacg cccacattct gacaagtaag gaaagaagaa atggccggat
     9961 catcagacgg atagtcttgt gttttatcaa agtaagaagg ttccaaggca gtagcaaaac
    10021 cattttttcg agaaataacg aaagcatcgt catgcaagat cgaaacagag tgaccttccg
    10081 tatgttttgc taaggtaatc gttgattttc cagaaccgga caacccaaat acagccatcg
    10141 tataggtctg gtcattacta gcatattgtt tcatcccacc gtggcaggca ataaagccat
    10201 tgcgatttcc caatgcccaa gcaagcgtca aagtcgcttt ttttaattct ccaaagtaac
    10261 gtaatcctag cacagccgct gtattatgga gagcatcaaa caaaatgagt ccatttggaa
    10321 atgtttcatg tgtccattcg ggatcacaaa agatataaag atctccctca tcaaaggaaa
    10381 cagacttttg ataagtctct aagatcttcg aattcgctgg ctgaaaattc agcaaataag
    10441 aatacaaatt gttctcaaat ccttctggaa tcagcaaatg actttgcaca gaaaattctt
    10501 cagataggcc aacgattact tttgtatggt aaaactggcg cttgcgactt tgatacacag
    10561 cttctcttaa aattttctcg tatttgcttt gttccttgtc taagtcctca aagatccgcc
    10621 gagcacttgc tgttcttccc acaatgcttc catcattgaa tactagtgtc ctaacatcag
    10681 ctggtaaatc tagttcttca gcatgtgaga ttgttaaatc tgtgatgatc gttcctggac
    10741 tcccttttgc tagttgataa gctgtcttcc tatcaaaaac ttcatgaaca ttattaccgt
    10801 aaaatgtcgt ttctacaatc gatcgaatac tggataacag tggatttcca cttgtgattt
    10861 cgtttaattc gagactctct tttgtactca tggctcctcc tcattcccta aacaaaaaaa
    10921 cgttttcttt attatacatt attcgagttt ttatttgtac tgctgcgctg tgggaagcaa
    10981 acgagttatt tttcacacaa aaaaaccgag aacttgaata aacaagtttc tcggtttcat
    11041 cattttcctt ttatcggctt agtaccagcc gtttgctaac cagaatgttt tagcagcatc
    11101 ccatgaacca taacgagatg ttacatattg ttctgctaca cgttcttgat tggcagctga
    11161 atagtcgccg tttaagtatg aagcatctaa ttgataacgg ccgatgtaac gtccgttagt
    11221 agctgtgtat gaaccgcctg attctttttg tgcgatccat tcttttgcag agcttgaagt
    11281 tggcgctgtt gcagcagctg gggcagcagg agctacttca actgtttcaa caggtgcaac
    11341 gtatgtatgt tcttgcgttg ctgtttcagt tgtagatgct gtattttctg ttgttttgtt
    11401 ttctgttgtt gctgaagaat catttgaagt tgggattgtt aattgttcac caacataaat
    11461 gcggttgatg tttgcgatcg aatttttttc agcaattgca tcgatcattg agttgtctcc
    11521 tgcaaatttt tgtgagatct tagataatga atcacctgat tttactgtat aaacttcatc
    11581 agcgtgagca tttgtagttc ctacaaacat tgcagtagca ccagcagcaa aagttgtacc
    11641 taaaacaatt ttcttaaatg aattcatatt aaactccttt ttttctccgt tttttattct
    11701 ttcgacgcta ttaactttat catttagaaa tatttcatag gtaaaagaaa catgacattt
    11761 aatgacaaaa taacgaatta tttaatattt gtaacattta aacaaatatt tttttgatac
    11821 aaaaccataa aagccttgtt gtataagcaa agtaatcgtt tttctatgtt tttttatttt
    11881 tgaatgaaaa acgcagattc tgtaacattc actgcaataa tccataaaaa aaagcaaaaa
    11941 aatttttgat ttttatcaaa ttctcttaaa aaaatgtaaa aaatacaaaa aaaccagtaa
    12001 ttgttacaac aattactgga caaaaacttt gaataatgtt aactattttt ttattttaac
    12061 tttctccgca ataatttctg ggcatgttcc aattcgttta taacgacttc ttctgtttct
    12121 ttagctaata tttcatctaa tacatcaagc catttttccg gttcttttgt tcctagacgt
    12181 ccaatagccc aagctgctgt tcctctgatg acagggcgga catctgttaa acattctgaa
    12241 atctcaggca atgccgttcg atcacctaga ttagctaaag caatcaatgc gtttctctgc
    12301 aaaggtttct tcccacgcca tgaaccagct aaatgcccaa attgctgttt gaagtcttta
    12361 ttagacatcg aaagcattgg ctttaatttt ggatatattt cgtctacttt tggttccatc
    12421 tcttcatgaa aatgaaaatc ttttccttga ttgtaagggc agactaactg gcagatatca
    12481 catccataaa tgacatttcg cattttttta cgatattctt ccggcatcat cccttttgtc
    12541 tgagtttgat aagacaaaca tcgctgggca ttcattcttc cgtcaccaag caatgctttt
    12601 gtcggacaag cagtcacgca gcgcatacag tcaccgcaac caaattctcc tggtttatca
    12661 ggctcaaata caatattagt aacgatctca ccaagataga caaatgaacc gaactcttca
    12721 gtgatcaaca atccgtttcg tccaataaat cctaaaccag ctcgctgtgc tacagcgaca
    12781 tcgatcagtt ctccagtatc tacttgcgga gctagacgcc attcctcttc tttttgccat
    12841 ttttctgctc ttgtttggat gaattcgatc aatcggttca aacggtctct gagtatatca
    12901 tggtaatcga tcccccaaga agcacgagca aactgcccgc gtttttcatc cctaggcact
    12961 tcttcatgga tcctagtagg atacgcaagt gcaatggaaa tgatcgattt cggctgatca
    13021 aatgtcattt ctggataaag acgctcatcg atatttggat gttcaaagcc agaagtatgg
    13081 ccagctgctt tttgttcttc caacgattct tttaatgaat caaaaggttc cgccgtggtg
    13141 aacccgattt tgtcaattcc taatcgtttg ctttcttgta tgatttcttc ttttaatgtc
    13201 atggtcttcc tcgcttgctg ttaacggctg tataacccat aatatagttt ttcttttttc
    13261 agctggacaa actggatctg ctgatcggca atcttctttt cttccatcca tttttttctt
    13321 gcagcaaata cttcccaata atttgttgaa attaattttc ttttgttatc taatgcatta
    13381 aaaaaattca atgaaactgg ttttgtactt aacagttcat ggagccttac ctcttcccat
    13441 ggcgaaaact cagacagatc gcgggaatac aatacttctt catagagatt tttttgctgt
    13501 gtgtacgtga atgtttgcgg gattttccca ggcctagcaa tttctactag acgattataa
    13561 aacatattca ttaatttgct gttggcaata aattgacttt tataataggc cgactggatc
    13621 tttttgatta ctccttctgc tttgatgact gaaaataatg caggccatgc tttgacggtt
    13681 atttcgtcgt tttgtttaac taatacgcca ggtgtgaagc cgactggaga aaggaacaca
    13741 aaataaccga taccggtatt ttcatctaaa ggctgaaatt catcaaacaa ccatttgcct
    13801 atgtacagct cttcatctgg ttctgttgtc tcattttgat ttgctatgaa taatttagct
    13861 aattctgctt caagaaattg aaggtcttga tccttgtcgg tattttcctg ctggctgatc
    13921 aatcgaaaga cttcttcttt aatcgtatat ttatctttac gtgtaaaatt catagccaca
    13981 ccttccttcc ttactctaac tataacggaa tttcttcaaa aaaggtatct gtacgacgaa
    14041 aaacagcata attttttttc atatctctta taaaaaatgc aaggtctgct cctcaagcta
    14101 gaccttgcac ttttcagctt tcttttgttt gtgacaaacc ttcatggatc gtttcaatat
    14161 tccatttcat catctgatag taagaatctc cttgttctcc ttcttttgct atggaatcag
    14221 tgaacagttt atcatagatt ttcaaacccg tttcttttgc tacccgttcc atgcttcttg
    14281 agtctacact ggtttccacg aataaaaccg gtacttcttt tgctcttatc tgatcaatga
    14341 tcgctttcat ttgatcaggc gtaccttgac tttctgtatt gatctcccat atataagctg
    14401 ctggcaaatc atatgctcgt gaaaaatact tgaatgcccc ttcacttgtt actaataatt
    14461 ttttgttctc ttcgatagaa gcaaaacttt ccttcgcttg tgtatctaat tcttttagtt
    14521 tttccacata tgcttctgca ttttttttat agagtgtcgc attttctgca tctttttcag
    14581 agaatatacg tgcgatttcc tccacatatt ttattccgtt agataggtct agccaagcat
    14641 ggggatctgc ttttgtatgt tcttcaccgc tagttaaata aagaggttct acatttttgc
    14701 taactgcaaa ataatctttt ccttcttctt ttttagccgt ttccatcaag ttatcgaacc
    14761 agctgttacc tgtttcaaga ttcaaaccgt tgtataaaat aacatctgca tcgcttgcct
    14821 ttttgatgtc ttctggtagt acttcatatt catgcggatc tgttccgact ggtacgatac
    14881 tgtggatatc tatttgatct gttccgacct cttttgccat gtccgccaag atcgaattgg
    14941 tagccacgac tgacaacttt tctttacttc cttcatccgc ttggtcagaa gcctgctttc
    15001 cgcaaccggc taataccaag aaactaactg ccaagattaa aaagagtgat ttttttgttt
    15061 tcatctatct gcttcctttc tgaaataaaa ttccttttgt tggagaaaat aaaaaagcaa
    15121 ggataaaaaa tgcggtacat gctaacacga tcgtagctcc tgatggccaa ttgtaactat
    15181 aactgaaaaa cacaccgaca actgcactta gcataccgat tcctgcagct gtaatgatca
    15241 ttttcagtaa atggttcgtt agcaagtaag ccgtggcggc tggtgtgatc aacatggcaa
    15301 tcaccaagat tgttcctact gtctgtaaac tgactacagc cactaatgtc aaaaagaaca
    15361 tcaaaagata atggatcagc gatgtgttca gcccataagc ttttgccatt gtcggatcga
    15421 atgatgtgat cttcaattct ttataaaaga aaaagacaaa tatcaagacg attccactaa
    15481 cgagtgctgt cagcaacaaa tcgctttccc taacagctaa gacattccca aataaaatat
    15541 gatacaaatc tgtcgcactc tgggcatatg aaatcaagat aatccctaat gcaaaaaagg
    15601 agctaaagac aattccaatc gctgtatcat ttttcaatcg gctccgctga gtcacgaaac
    15661 caatcactgc tgctgttagc atcccaaaag cagtggctcc aaagatgtaa ctaaaaccaa
    15721 acatataaga aatggctaca cctggaagaa ctgcgtgaga gatagcgtct cccatcaaag
    15781 acatccctcg taaaataata aaagaaccga tgactccaga agcaagtcct acaagcatgg
    15841 aagtgaccaa agcgtattgc aggaattgat aattcattaa tccatcaata aaggattgga
    15901 tcattttttc tctcctcctt ttactaaatg tctgatgatc tcaccatagg ccaattgaag
    15961 gttcttcgat gtaaagactt cttgtactgg accggaagcg atcagctgtt tatttaaaag
    16021 aataacctca tcgaaatatt cttctacttt atgaagatca tgatggacga tcaaaatcgt
    16081 ttttcctgaa ttcttcaatt cctgcaagat gtcaaagatc tttcgttcac ttaacgcatc
    16141 aatccctacg aatggttcat ctaaaaagat ccattctgct ccttgggcta gagctcttgc
    16201 aataaaaact ctctgaagct gtccacccga tagttcgctg atctgtcttt tggcatattc
    16261 ttccatccct acttttttca aagcttgtct tgcacgttct ttttcttttt tcccaggtct
    16321 ttgtccaatt cgtaaagatg gatatgttcc taaaagtaca acgcctaata catcaattgg
    16381 aaaggaaaga tccaattcac ttcgctgttc cacgtaggct atttttttac ggactgagtt
    16441 taccgactgt ccagaaaagg tgactttacc agtagtagct ggtatcaact ctagcaaaga
    16501 tttcataaat gttgattttc ctgcaccgtt tggtccgata ataccggtaa ttttttgtgg
    16561 atttatcgtc aagttgatag ttttcaaaac agttttccct tgataagcgg ctgaaaggtc
    16621 ttgaattaca atggccgtac gttccaaatc ttacactcct ttttaggttt acctaacttt
    16681 ttatttaaat atagtttaac taaaatggaa agcattttca agtagaatga tgaaaaagtt
    16741 tttttcgaat tttcctcgca ttttatgaaa attttctgta gaatcacatc aagagttcaa
    16801 taaggctaac ctaataatga aaaacatgtg ttgaaacgtt tgattatttt ttcttgttga
    16861 ctcaacaacg aaaggagttt ttgtatggaa gaagaaaagt taactcgaag tcttagtgcc
    16921 cgtcatatcc aaatgatcgc actaggtgga acgatcggtg tcggtctgtt tatgggtgcc
    16981 tcctcaacca tacgttggac agggccctca gtgatgggag cctatgcgat tgcaggattc
    17041 tttttgtatt tgattatgcg tgctttaggc gaaatgcttt acgttgatcc ttcgactggt
    17101 tcttttgcaa attacgcgag cgagtacatc catcctgtgg ctggctactt gaccgcttgg
    17161 agtaatattt ttcaatatat tgtcgtagga ataagtgaag tgattgctgt aggatcttat
    17221 atgaattatt ggtggcctga tttgccggca attattcccg gaatcattgt cgtcttgttt
    17281 cttatgctgg caaatcttat ttctgtcaag gcgtttggcg aattagaatt ttggttttcg
    17341 atcatcaaag tcataacgat cattttgatg atcattgcag gtcttggggt aatcttattt
    17401 ggatttggta atcatggtca ggcagtaggg atttcaaatc tttggaaaaa tggtggattc
    17461 ttcactggag gcgtcaaagg atttttcttt gcattatcga tcgttgttgc ttcctatcaa
    17521 ggaatcgaac tgatcggaat gactgctggt gaagcagaga atcctaaaaa gacgatcatt
    17581 gaagctgtcc agtccactat cggtcgaatc ttgatttttt atattggtgc tatttttatc
    17641 attgtgagta tctatccgtg gaatcaattg agtgagattg gttcaccttt tgtacaaact
    17701 ttttctaaag tcggcattac atttgctgca ggactgatta attttgtcgt gattacagcg
    17761 gcattatcag gttgcaattc agggattttc agcgcaagtc gtatggtcta tacacttgcc
    17821 ataaatggaa agatgtctaa aaaatttctg aaactatctc gtcacggtgc gcctttttat
    17881 cctgtcgtag caatctcagg tggaatctta attggtctga tcttaaatta tcttctacca
    17941 atgttcatca accagtcaga aaatattttc gttttcgtat acagctcaag tattttgcct
    18001 ggtatggttc cttgggtagt gattttgatc agcgagattc gcttcaaaaa gaagcacgca
    18061 gataaaatgc atgatcatcc ttttaaaatg ccactatctc cttatacgaa ttatgtgaca
    18121 cttgcttttt tagctatcgt attgattttc atgtttatca atcctgaaac gagaatctca
    18181 ttgattattg gactcgtttt cttgctttac atgacgatcc attactttgt acgcgaaaaa
    18241 agaaccggaa aataaaaaaa gaacgaagct tcaccttagt ggaagcttcg ttctttttta
    18301 ttgcttttat caattcaatt ttagcgtctc accgggagtc aggaaataat tctccatgct
    18361 catcccattc agcgacaaga tcgtttctac tggtacgcca gttcgttcgg ctatttgatt
    18421 tggaccttct ccttccaaaa ctacggttgt cgcagcctgt gaagtcgcgc tgttggtatt
    18481 agtttcagag gaatctgttg tgtcttgtgt tgttcgagct tgcatttcag aagcttctac
    18541 cgactctgct gtctcagaat cagaagatgt tgtgtcttgt gtgcttgttg actctgcttg
    18601 aagagaggcg ctagtctgca aataaatatc ggaaatctta gcgacatgat tcgtataatt
    18661 agccgataat tgattgatca aagtatctaa gtctacaccg tctttatttt ctgctgcctg
    18721 atacgctgca cgtaattttc tgatcccttc gtcggagatt gcttgaagct cacgtgcttt
    18781 ttggttagca actgctgata aaccagctat tccctcttga tttccctgaa tttctgtctg
    18841 gtattcttca atcaatgcag gcgtcttttc ttcgatcttt ttcgaataat catttacgat
    18901 tgcttgaagt tgctctggca aaccatttgc tgttttttct tcagaagttt gtgtctcttt
    18961 tgttttagtt gatgactcac ttgtttgttt cgtctctgtt ttctttgtcg ttgtttccgt
    19021 tatggtcgta cttttcgctt ctgacgaatt ttttccatga aaatatagac ccgcaactcc
    19081 tcctgctatg atcaaaaaca cggcaactgc tgccccaatc atgatcatcc gcttacgagc
    19141 tgcctgtttt tgctgtcttc ttcgggtcat ccgaacattt tctccccact cattttcatc
    19201 atacattttt ttcaccacca atttttatgt ataatagcgt tatcaaacgc ttcatattct
    19261 tattgtagca aataattgtc gctgtgcaca tttttatctt tgttatttat aagaaaattt
    19321 caccagttga gatgattcca agattgtccg tcgatttctc cttgcagctg cattgttcgt
    19381 tcgtctatct cagccatcag tttctttatt tcatataaga gcgcacggtc ttgatattct
    19441 gatttttcgc ttaattcatc taattgttgg atcagccaat catttgtcat aatgaagttc
    19501 ctttcatttc ttgcagtgta aaggtcaagt cttcgatctg ctcttttgcc tcagtcagtg
    19561 cttctacgat atatgcttgt ttttcagatt cttcttcctg cattttctga ttttcctgta
    19621 ctctttgaat aaaccagtca atccgctgag tcagcgatgg tttgccttcc aatgagagat
    19681 actgctgata agcaattagc ttctcccaac gtttttcctg ggataaatac ataaattgtg
    19741 ctaaaacgaa tggcggaaga taggtcatat ggaatttatt tgcgattcgc tgatacggcc
    19801 tcaaaaattc ggaaatcgta tattcttctt ttcctccagc ttggtattct ttttccgcca
    19861 cacctgttgt caatacgatt cctagttctt tcccttttaa tacatgtgct gctcgttcca
    19921 agacattatc ttgccaaatt tttaaatgag caggagaact ataccagtaa aacggaaact
    19981 ggaaaatgat ccgatcatgc tgggccaaga gctgtagttc agtctctata tctatttttc
    20041 cgtctggata acttgattcc aaatgatgcc aagtagctgg taaaccagca gaagcttctt
    20101 tgaaaaattg ctgatttaaa gattcttcga tcgttggatg gctaatgatg ataagtgtac
    20161 gcatcccttt tcctcctttt tagtcttcgc tttacagtgt agcataaccg ccacaagttt
    20221 cttttgccga tgcttgtcat tttaaccaga ctaatcaggt tgtccaagaa actgcggttt
    20281 gtttttccaa ctgttttttc aaggtatcca aagcaatatt cttaaaattt tcgtttttca
    20341 tacgtttacg atagttcgta gccgtttctc cggtactctt tttgaacatt cggctaaata
    20401 cgactagact attgaaccct acttgatagg caatactttc cacggattca tccgtcagag
    20461 aaagaagaaa cgcccctcga ttgatccgta ccccgatcaa atattccttg atactggtac
    20521 ccatatgatt tttgaatact cgcgacaaat ggctccgatt gaccgctaaa tgctgggcga
    20581 tttcctcaac agacaatttt tcagcataat gtgcctcgat gtatttgact gtttcaacag
    20641 ctaaagagga atgaaccttt tgtacaccac cgctgacctt tccgccatct tttaaaagga
    20701 ctgataaaaa acggtaggtt aatgctgtta actgtaattc attttccaag gtttcttccg
    20761 tatctttcat gcattctaaa ataatgtcga tatatttttg tatgtcagaa gagaccatcg
    20821 tgtattggtc ttctctgaaa agcgactgcc gaatgatttc ttctgcagca ctcccaccaa
    20881 atgaaagcca gcaatacatc cacggatctt ctccatctga taagtaaaac gtcgagtctc
    20941 ctggacgaat caagaacaga tcaccttttt tcaattggaa ttgttgattt ttcacatgat
    21001 aagatccttt gccttccatc acgacatgca ggatgtaatc attgcgaata gcaggaccaa
    21061 aagaatgaaa cggcatcgtt ttagagaaac cacaaaaatc aaaatacaat tctttttcta
    21121 cttgttgatg ttcctttttt aaaaaaatcg attgctccac gtctatccct ccttactcct
    21181 ttagtataat gcaacaaaaa gttaaataaa agtcacagaa atatattaaa aaggaagcga
    21241 tttcttgtta agtttaagtc attaaaagat ctttgttatt cgttgtaacc ggtttactta
    21301 gtattatata ttgaacagga gaggaataca gattatgaaa agcaaaatga tccaacgtgt
    21361 gtcctacgct ttaggcgctt ttggacacga cacattctat gttacattaa gcacttattt
    21421 tatggtattc gtgacaagcc agatgttcgc aggaacagat aaggcaacga atgcaaaaat
    21481 gattgctaca gttacaagct tagttgtagg tatccgctta gttgaaatta tttttgatcc
    21541 tttgattggt ggcatcatcg ataatactcg tacaaaatac ggtaaattca aaccatggtt
    21601 agttatcggc ggcgttgtta gttccgtact cttggtagca atctttacca atttctttgg
    21661 cttagctact cataatacga ctttatttat catattattt gcaatcgttt tcatcttatt
    21721 ggatagtttt tattcattta aggatatcgc tttttggtca atgattccag ctttgagtac
    21781 ggaaacaaag gaacgtgaaa aatttgctac gtttgctcgt ttcggctctt ctctaggtgc
    21841 aaatggtact actctagtcg ttgtccctat cgttactttc tttacctatc ttgttactca
    21901 taaacatatt gaaggcgctt caggctggtt ctggttcggt gtgattgctg ctgttatttc
    21961 aggcggtact gcgattatca ctgccttggg cacaaaagaa gtcgatactg cgatccgtca
    22021 gcaaaatgaa aaagctggga tcaaagatgt gttcaaagca gttgctcaaa atgatcagtt
    22081 gatgtggctt gcccttgctt atatcgctta tgcgattgcc aatgcagcaa caactgccgt
    22141 attattctac ttcttcaaat atgtacttgg ccaaccaact gaattttgga tcgttggtct
    22201 agttgctgcc ttacttggtt tagtagctgt tccactattc ccaatgctta cacgcgtcat
    22261 ctctcgtcgc tacgtttacc ttggagggat cgcaatgatg atttcttctt actttttctt
    22321 tacgatcgca ggttcaagtt tgccaatcgt tatcatcggg ctagtattgt tctacttccc
    22381 tcaacaattg attttcttat ccgctttgat gacgatcaca gactctgttg aatatggtca
    22441 atggaaaaat ggtatccgta acgaagctgt tactctatca attcgccctt tactagataa
    22501 aatcgctggt gctttgtcta acgggatcgt agggtttgtc gctatcgctt ctgggatgac
    22561 tggtaatgct actgctgctg atatcactgc tcatggcgta acgactttca aagcttatgc
    22621 attctatgct cctgctgctt tgatgatttt ctccgctatt atttttgctt ggaagattac
    22681 attgacagag aaaaaacatg cacaaatcgt tgagaaattg gaaaacaaat tggctccagc
    22741 tgatacaatg gaagattaac ttcacgatgc agtagttcct tcccattaag aaaggatctt
    22801 gaaaatgaag attacagaaa aagattttgg ccaaggttat cacttgataa ccttggagaa
    22861 caaaaacaag ctagcacttt ctatctctga tttaggtgct agaatcgtca gtttaaaatc
    22921 aaatgatcga gaattagttt tgggatttga caccgctgaa gaatatatcg aaaaagatcc
    22981 gtatatcggt gcttctatcg gtcgcaccgc agggagaatc gaaaatggcc gcttttctct
    23041 caatggaaaa acttaccaat tagccacaga tccaaaaact ggacataatc tgcatggtgg
    23101 tgctcctgga tttgaattaa aaaaatggtc ttatgtcatt ttgaatggcg aaaatgaagc
    23161 ttctgtcatt tttactacta caagtcccga cggagaacat ggttttccag gtacaatgga
    23221 tgtggaaatc cgctatactt tgacaaaaga taatatctgg cgagtgacct ctcgcggcac
    23281 cagtgaccaa gatactttat tcaatccgac aaatcatgtt tacttcaact tgacgggaga
    23341 tgcttctcag tcaatcgatc aacatgagct ttggctcaat agcgaagctt atgctccttt
    23401 gcgaacagat agtattccta taggggtaaa agaaaatgct gcaggaagtg ctttcgattt
    23461 tcaaatacct aaaaaattag cgtccgtttt tgctagtgat ttggatcaaa aaaatcttgt
    23521 tgacggaatc gatcatccat ttttcttaaa agaaaccggc ttgggtaaag aagccgctcg
    23581 cttgactagc cccgataaaa gaatccaagt agatattgct acagatgctt ctagtgtggt
    23641 tattttcact gcaaatttcg gcacagaaac accagaaatg cgcaaccgaa aactggcaca
    23701 tcacggtggc atcacatttg agactcaaac agctccaggt gcagagcgct tctcagcatt
    23761 tggttcgatt catttaaaag ccggatcagt atttgaaaca gtaacagaat tcaaaatcaa
    23821 aacaagaaag gaataactca tcatggaaat caaaagaagc ttaaacacaa aatttgccga
    23881 aacattcgga cctaaaaaaa ctacacaata cttctcacca ggacgcatca atttgattgg
    23941 tgaacacaca gattacaatg gaggccatgt cttccccgct tccatcactt atggaacgca
    24001 aggtgtagca gcacctcgag acgataataa aatattagtt tattccacaa actttgacga
    24061 tatcggtgtc attagtttta ctttagatga gctagaatat gataaaaaag caaactgggc
    24121 aaattacgta aaaggaatgg tccttaaatt aaaagaagct ggacactcaa tcgatcatgg
    24181 gtttgagtta ttagtggaag gaacaatccc taatggtgca ggactttcca gtagcgcttc
    24241 attagaatta ttagtaggtg ttgtattaga agatctgttt gatttaaaaa cagatcgctt
    24301 ggaactagtc caaacaggta aaaaagtaga aaatgaattc atcggtgtca attcaggtat
    24361 catggatcag tttgccatcg gcttcggtga gctagatcat gcaatcttat tagatacaaa
    24421 tacgctgaaa tacgaaatgg ttccagtgaa actagatggt tatgcaatcg tcatcatgaa
    24481 tacgaataag cggcgggaat tggcagattc aaaatacaat gaacgccgta gcgaatgcga
    24541 agaagccttg gcacgtttgc aaaaaacttt gcctatctct tctttaggag acttagatga
    24601 agaagaattt gaatcaacta ttgaccaaat cggcgatgat acattgatac gcagagctcg
    24661 ccatgccgtt tctgaaaatc agcggacttt gaaggcaaaa gctgaattag aagctgggaa
    24721 cttagaagca tttggtcaac tgttaaatga ttctcaccac tctcttcgct atgattatga
    24781 agtaactggg atcgaattag atacactagt agatgctgct caaaaacaag aaggtgtctt
    24841 aggtgcacga atgacaggag ctggatttgg tggctgtgcg attgctcttg tcaaagaaga
    24901 aaatatacct gccttcaaaa acaatgtcta tgatgaatac atgaaagttg tcggctatgc
    24961 tccggaattt tatgttgcac acattggaaa tgggacaaca aagatcgatc cagaagctgt
    25021 tcatgtttga taaaaaaatc aacgatctca gctaaaaaca aatagataaa aataacctct
    25081 cagcaatttc caaatgtgag ccttttgctc gtatttgaaa attgctgttt tttattgaca
    25141 cggaaagaga acgtgtgttc taattgtgtt gaagaggtga ttgttatgtg ggcgaatcaa
    25201 aatccggtat ttgtttatga aaaagaacct tcaagagata ttttatgtat tgactgcaaa
    25261 tctttttacg cctccgtaga gtgcgttgaa aaggatcttg atccccttac aactaaatta
    25321 gtagtcatgt cctatccgtc cgattcgaca gaaacacggg gtagcggatt aatcttggct
    25381 tccagtcctg cagcaaaaaa agcttacggc atcaccaata tcagccgtgc cagagatctt
    25441 cccttcccct atccaagtga tttatatatt gttgccccaa ggatggccta ttatatggaa
    25501 aagaacagag aaatcaattc tatctataaa aaatatgcag acgaagcgaa ccatcatgtc
    25561 tattccgtcg atgaaagctt ccttgatgta acaaatagca tggcactctt tggtaaaaca
    25621 aatgcgtacg acatggctaa actgatccat aaagatgtgt ttgagcagac cggaatctac
    25681 acgactatag gaattggcga taacccgcta cttgctaaac tagccttaga caatggctca
    25741 aaagacggaa agcaaatgtt tgctgaatgg cgttatgaag atgtaccaga aaagttatgg
    25801 aaaatctcag atatcactga cttttgggga atcggcaaac gaacagcaaa acgtctgaaa
    25861 caaatgggta tacattctgt ttatgattta gctcacgcgg attattatca cttgaaaagc
    25921 aagctagggg tcatcggtac tcagctttat gcccatgctt ggggcatcga tcgaagtttt
    25981 ttgggacaag aatatacacc aaaatcaaaa agtatcggaa atagtcaaat cctagataga
    26041 gattatacaa gacgagaaga aatcgagatc gttatcaaag aaatggccga ccaagtcggc
    26101 actcgcttga gacgatctgc agcaaaaaca caagtagtca gcttatgggt aggatactct
    26161 ttaggctatc ttgatccaaa tggcaagacc gggtttcacc agcaaatgaa aatcgaagcg
    26221 acaaatgcta gcagagatct tgcagatgct ttattgacca ttttccacca gcattaccac
    26281 taccaggata ttcggcgtgt aggcgtgaac tgttccgacc tcgtatacgc gacaggttta
    26341 cagcttaacc tttttgaaga tcctgaaaag cagataaatg aagcgaaagt tgattttgtt
    26401 gtcgatacga ttagaaaaaa atacggcttt caatcaatca tccatgcgca tagtctcttg
    26461 caaggaggac gcgccatcgc acgtagttct ctcgttggcg ggcatgcagg tggtatgagt
    26521 ggattagaag gtggaaaaga tgagacggac agcaaaaaaa ttcattgact ataacgagta
    26581 tcgagatcgg ccatttggat taaaatgggg gactgctttt gcgatggaag aactagtcaa
    26641 cggtatcaaa aaaatgaaga agaagcacgc aaacagcctc ttcctaaaca acaaatgaca
    26701 ttgcaagaaa tcgatagtat actgacagaa gcctttttat ctcgtaaagc agtaatcatt
    26761 cagctcaatt taaaagatga atttggaaga ctcttggatg aggtcgaagg gcacttcatt
    26821 ggtgaagcct atgaagatta ctttatgatt gaccatcagc cgatattgtg ggaagacgta
    26881 cggtatattg agttaaagga aacaaaaaaa tggtttgtga catgagaggt tgtgacagaa
    26941 gtgatcaact tcaaaaaata agaaaggatt tttcgaaaat tgcttcttaa atttttgtgg
    27001 aattttggct tatttttcga agaagcaact tctggaacaa cgtatattag atatcagagg
    27061 ttgtgaaaaa gtcgcttagt tttgagtaac aagccaaggc gctgatttca caacctctgt
    27121 ctatctatcc atctattcgg taagattcat gcatgacgtc ttctttattt agtatgtaga
    27181 gccctttttc ttctgaccat tcaacataaa tcagctgttt tacatctgca tagccttctt
    27241 tcttcaagtt ctccataagc catgcttcag tcaattgatt ggactgaagc actttatgct
    27301 gaatttgccc ttcatctaca agcaggatcg ataaagcttt gtcttcatct gattttttca
    27361 atacactcat ttgaccggca ttctctagga taacatgttt ggcattttca agaaaaaagc
    27421 attcttgctg tcttaagatt gctcgcaact gctccatctc gatatggtta tttgtcaact
    27481 ctgtcatgtt gatgacgccg tctttgatta gaacagatgg ctcgcctttg acccaacgat
    27541 tgaccttttc atttttttgg acgatacgtt cgataccata aatcattact gcccaaagcg
    27601 caatggcaaa taggacatgc cctacatgga cattgtcatc ataggttgat tcttctaaga
    27661 tcccacctaa aacaagcgta tagactaaat caaacggtgt gatttctgac atggatttct
    27721 tcccaagcaa acgtaccact aataataaac cgatcaaccc gaacaccagt ttcattgtaa
    27781 ttgaaaaaat cattttttct ccccctaact atctgttaat taaattatat atgctttctc
    27841 acgaacacgc atggaatata caaggaagaa atgtatcctt ttactaaaaa aaggactgtg
    27901 acactgtagt gacccccaaa agttagactt ttttggagtg gagaaatcca ctcctttttt
    27961 ttatgctcta aaatgatatt tttacacaac cgttacggtt gttttacgaa attggacg
//
LOCUS       DBBGSP010000039        27956 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000039 DBBGSP010000000
VERSION     DBBGSP010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.039"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(71..970)
                     /locus_tag="ACIZE9_001942"
     CDS             complement(71..970)
                     /locus_tag="ACIZE9_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC6093794.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            complement(980..1336)
                     /locus_tag="ACIZE9_001943"
     CDS             complement(980..1336)
                     /locus_tag="ACIZE9_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HGC6093795.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            1691..1987
                     /locus_tag="ACIZE9_001944"
     CDS             1691..1987
                     /locus_tag="ACIZE9_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HGC6093796.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            complement(2631..3584)
                     /locus_tag="ACIZE9_001945"
     CDS             complement(2631..3584)
                     /locus_tag="ACIZE9_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6093797.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(3607..4362)
                     /locus_tag="ACIZE9_001946"
     CDS             complement(3607..4362)
                     /locus_tag="ACIZE9_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093798.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            complement(4359..5318)
                     /locus_tag="ACIZE9_001947"
     CDS             complement(4359..5318)
                     /locus_tag="ACIZE9_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGC6093799.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            complement(5311..6261)
                     /locus_tag="ACIZE9_001948"
     CDS             complement(5311..6261)
                     /locus_tag="ACIZE9_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGC6093800.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            6411..6863
                     /locus_tag="ACIZE9_001949"
     CDS             6411..6863
                     /locus_tag="ACIZE9_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGC6093801.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            complement(6952..9219)
                     /gene="gshAB"
                     /locus_tag="ACIZE9_001950"
     CDS             complement(6952..9219)
                     /gene="gshAB"
                     /locus_tag="ACIZE9_001950"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HGC6093802.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(9406..10404)
                     /gene="ftsY"
                     /locus_tag="ACIZE9_001951"
     CDS             complement(9406..10404)
                     /gene="ftsY"
                     /locus_tag="ACIZE9_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGC6093803.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            complement(10415..11224)
                     /locus_tag="ACIZE9_001952"
     CDS             complement(10415..11224)
                     /locus_tag="ACIZE9_001952"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6093804.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            complement(11233..14814)
                     /gene="smc"
                     /locus_tag="ACIZE9_001953"
     CDS             complement(11233..14814)
                     /gene="smc"
                     /locus_tag="ACIZE9_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGC6093805.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            complement(14834..15520)
                     /gene="rnc"
                     /locus_tag="ACIZE9_001954"
     CDS             complement(14834..15520)
                     /gene="rnc"
                     /locus_tag="ACIZE9_001954"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGC6093806.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            complement(15868..17649)
                     /locus_tag="ACIZE9_001955"
     CDS             complement(15868..17649)
                     /locus_tag="ACIZE9_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC6093807.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            complement(17675..18589)
                     /locus_tag="ACIZE9_001956"
     CDS             complement(17675..18589)
                     /locus_tag="ACIZE9_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6093808.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            complement(18616..19578)
                     /gene="opp4B"
                     /locus_tag="ACIZE9_001957"
     CDS             complement(18616..19578)
                     /gene="opp4B"
                     /locus_tag="ACIZE9_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HGC6093809.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            complement(19578..20522)
                     /locus_tag="ACIZE9_001958"
     CDS             complement(19578..20522)
                     /locus_tag="ACIZE9_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093810.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            complement(20523..21527)
                     /locus_tag="ACIZE9_001959"
     CDS             complement(20523..21527)
                     /locus_tag="ACIZE9_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093811.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            complement(21795..22037)
                     /gene="acpP"
                     /locus_tag="ACIZE9_001960"
     CDS             complement(21795..22037)
                     /gene="acpP"
                     /locus_tag="ACIZE9_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGC6093812.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            complement(22159..23160)
                     /gene="plsX"
                     /locus_tag="ACIZE9_001961"
     CDS             complement(22159..23160)
                     /gene="plsX"
                     /locus_tag="ACIZE9_001961"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGC6093813.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            complement(23209..25245)
                     /gene="recG"
                     /locus_tag="ACIZE9_001962"
     CDS             complement(23209..25245)
                     /gene="recG"
                     /locus_tag="ACIZE9_001962"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGC6093814.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            complement(25362..27044)
                     /locus_tag="ACIZE9_001963"
     CDS             complement(25362..27044)
                     /locus_tag="ACIZE9_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGC6093815.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            complement(27096..27458)
                     /locus_tag="ACIZE9_001964"
     CDS             complement(27096..27458)
                     /locus_tag="ACIZE9_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGC6093816.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            27728..27916
                     /gene="rpmB"
                     /locus_tag="ACIZE9_001965"
     CDS             27728..27916
                     /gene="rpmB"
                     /locus_tag="ACIZE9_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGC6093817.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
BASE COUNT         7719 a         6053 c         4933 g         9251 t
ORIGIN      
        1 atggatctac tgctcttact tatccttatg ttttacaagg tattttcttt tacacattac
       61 taatgctgtc tcaatacgga acgattgtca tcgcttgttc aaattcctct tgcaaatgtt
      121 gtgtttgata ggcctgaaaa gctgggtgat gggcacgcaa gaggacacgt aatttcatag
      181 gatcatagct gtctagcaac tgttctttca agacaaaatc tcgggtcagc tgccattcat
      241 aataataacc aaaaggtctg cagctgtaaa tcgtgtgacc gatggattta tcttcaaagc
      301 gacgatgcgt atggccaaaa actacttgtt tgatatttga ataacggtca agtaattctc
      361 cgaatgattc tgatcctaaa aatgcattta atttgttcca acgctcataa ggagcagatt
      421 gatacatgat aaatgcccgt ttaggaacga aatgagtgga taaaatcacc tcaagttttt
      481 ttgcttccag ctggtctagc aaattttttg cagctgcaag catttctgca ttgacctcga
      541 gatctgtttt cccacgctgg atgaaccgat cataccaata caaacgcttc attcgtacga
      601 ttgcctcgta atctttcaat tcggaaaact gatagtcgta ccagccattc atccctaaaa
      661 gaacggtctg ctcatttaaa gcaatatacc gttcatttaa aaaatgtggg tctggaaaat
      721 ggtccatcat ctgttcattg ggcacatctg ccaactcgtg attgccgaaa tgaaatgtcg
      781 tagataatcc tttattgacg aaaaattcga caacagctag gcaacggtct actttattag
      841 ccgtatctcc ggctagatga agccgagtga tcttgtgctt ttgcaaaact tgccaaagct
      901 gcatcagctc tgattcgccg aatttattga tgtccacatg taggtcgctg atgatcgcca
      961 attttcccat tttatccctc tagtcttttc gaacaacttg caagttgcct tttctcaagc
     1021 cgcttggtcc ttttaattgt aaactattat aagttggttc taaagcaagt gtggatggat
     1081 catccatgta aagtattgca ctgtctttga ttttgattgg tccaactggt gtatcagcca
     1141 ctacagaata aagacttaga tctgtttgtg tatctttttt gacaatgatc aatcgaaatg
     1201 ccgtatccaa ttggcaactg acttggcttt ctgcaaatgg accgtcaccg ttttcgatat
     1261 ctaataaaag ttgatcgtct gcttctaatt tattcttcaa tacttcttgt gcttcttttg
     1321 tcacttctaa tttcatctgt atcacctcat gtcatagaat aatcacttta ttcatcagat
     1381 gcaactaatt tgtctggttc tgactgttct caatttattg gaaagtaagt cattcgttta
     1441 ttatgatttc tcttatcaca aaagagacaa ctttcccttt tcttcgttca gtttcttgaa
     1501 cggaaaaaga cccaaaaagc aacctgttat ttgtttaacc ttattccttt cttaaataac
     1561 aaaaaatact ataaaaaata aaaaaccttt aacaactatt ggaaaaagaa ttactttttg
     1621 ttcacggatt attaacaact cttcggtaga gtaaacttat caaataaaag acttctttgg
     1681 aggaatcact atgaaggaat atataaaaaa catctatttt atcgaagaaa cacaaaatat
     1741 cgagggttct tatattgaag taaaaacact ctttgtcaat gaagataaaa ccaaagcatt
     1801 ggatatttat aaaaaattag cttcaaaaaa aacgaatagt tttggattga tattaagcga
     1861 gtataaaatc aaagcagaag agagttattt ctatcaatta ctaaaacggt ggagtaagct
     1921 tcccgccgat ttttatcgaa aaatgcagat catcaactat caaccgcttg ctgagacaca
     1981 tgcctaaata gaggttgtga aatcagtgct ttgagctaat accgaaggtc agctgattga
     2041 acattgttta gaagagattg tgacaactgc gatttgcttt gagtaataag aacgctggac
     2101 agaaaatagc ttctcatatt ttctagtcta gtgggcttat tgccgagaag cagcagatgg
     2161 aacatcgttt agaagagatt gtgacaactg cgatttgttt tgagtaataa gaacgctgga
     2221 cagaaaatag cttctcatat tttctagtct agtggactta ttgccgagaa gcagcagatg
     2281 gaacatcgtt taaagaagag atcggtacaa aataaaaata tctaaattta agttttatct
     2341 aagtttcgct ttgtaccttt gattcaaatc aaaggaggcg atcttgatgc tgaaaaaatg
     2401 gatcacacta ttttttgcca ctccccattc tagaatcaac ccgtatgatg tagataatga
     2461 attcacgttg aaaaaagatt tctcaaataa ataaaaacca tccgtaaaat catcaatacg
     2521 attttacgga tggtttttga taacttcttt gaggataggc tcttgctatt taagaatgta
     2581 agaaacatta ttgttacata gtatgagagt ttaatcctct gttatttatg ctatttaaat
     2641 gcttgattca catcttcgat catcagtttc attgattcta aaccgccccc gcttaaatac
     2701 cagacatctg gttcaaggga gatgatctgc tgatttttac cagcattcgt ttgtgctacc
     2761 agttcattgg cagaaatatc atctttgctg tcgtctccac caatagcttt tgttctgtct
     2821 actacaaata agatatccgg atttttttcc agcacatatt cataagaaac actttgaccg
     2881 tgagtggatg cttcgatttg atcatctgct tgttcaaagc caaataaatc atggatgaaa
     2941 ccgaatctag aaccagatcc gtaggctgat aattgccctt cattcacaag tgtgactagt
     3001 gcttttttgt cagtagcttc tgctttcttt ttcgtctgat cgattgcact agataattcc
     3061 tctaattgag ttttagcttc ttcttgctta ccaaagatct cccctaaagc agtgacattt
     3121 tgctggaaag attcccatgg atttttcgca tctaaagaaa ggaaaatggt cggagcaatt
     3181 tgacttagat ctttttgaaa atctctttgt cggccagaaa tgatgattag atctggctga
     3241 agctgattaa ttttttctaa gtctggttct tttattccac ctgctgattc tactttttta
     3301 taggatgaaa gatactcagg aaggctgctt gtagctgctc caactacctt atctccaaca
     3361 ccaagagcat ccatcgtatc taaagaacca ttgtcgaata cgacgacttt ttctggatta
     3421 tttggcacct cgatttggtc tccattacta tctgttatcg tcaatgtagt ttcagtttgt
     3481 gtgctgcttt tttttgtgtc tgcctgactg gtgttgttgc tatttccaca tgctgctaaa
     3541 ccaaatgatg ctagaatcaa gatacctact actaattttt tcatctcttc tctcctaatg
     3601 ttagttttag aaataaagac agaatctgcg gccttcaatc tcacaaatcc gtatgtccat
     3661 ttcgtataat tcatccaata catctttttt tatcatttct tgggtcgttc cttgcgtaaa
     3721 taactgtcca tctttcattg caacaatttc gtctgcataa cttgcagcaa agttgatatc
     3781 atgaagaaca ataacaattg ttttcccgat ttcttgtact aaatttttta aaatctgcat
     3841 gatttgaacc gcaaaattca tatctagatt gttcaaaggt tcatccagta aaatataatc
     3901 cgtgtcttgc gctagcacca ttgcaatata cgcacgttgg agttgaccgc ctgaaagagt
     3961 gtcaatcgat tgatccgcta tttcttctaa cccaaggtgt tccagtgatt cctgaacgat
     4021 ttcctcgtct tttgtcgtca attttccttt cgtataagga aatcgtccaa attctactaa
     4081 ttctttcacg gtgatttgga catttatttc attcgattgt cgtaggatcg ataatttttt
     4141 ggctaattca ttggatttcc aagcctttac ttcgttatgg tctaaataga tttcacctgt
     4201 atcttttggt atcaaacgac tgatcatcga caacaccgtt gactttccag caccatttgg
     4261 accgataaaa gcagtcaact tcttttcagg aatcgttaac tgtacatctt taaccactga
     4321 ttttccatgg tacagtttat tgaccttttg taaatcaatc ataggatact cttcctttcg
     4381 cgaatcaatt ttgtgacaaa ataaattcct ccgacaaatt caacgacgac actcactgtt
     4441 gtattccagc cgaaaatctg ctctactgcg agctgtcctc ctgtcagaaa cagcatagct
     4501 accagaaagc ttccgataaa tagctgacca tgacgataag tagaaaagac acgataactg
     4561 atatttgcga caataaaccc taaaaaagta actggaccca caagagccgt tgatgtccct
     4621 gtcaaaagac tgacacaaca taaaatcaaa aattcaaaac gatctgtgtc tatcccgagg
     4681 tttactgctt gttcatttcc gagatggaaa acgtctagca catgtcgata tcgaaataac
     4741 aggtaccagc agccgataat gatcaaagaa gcaggcaaaa gatactgact ctggatattg
     4801 ccaaagcttg caaataatct gccttgaagc aaatcatatt cattcggatc catgatgact
     4861 tgtaaaaagg tactgacact accaaaaagc gtacctaaaa tcatccctga catcagtaat
     4921 aaaaaaagat tcgctctcat ttttttcaaa agaaagaaaa ataacaatag actcagcccg
     4981 accatcagcc caacgttcaa taagaaaaaa actgtacctg tctgctgaag catcgtcact
     5041 cctccgataa agaagaaaag gaccgtttgg acaaggacat ataacgactc aagtcccaat
     5101 actgaaggag tcaaaaactg gttatgcgta attgtctgaa agctgattgt ggcactgctg
     5161 acagctagcg agacaaggat aaatgcaaaa attttcttac tcctcaatgc acatgcaaaa
     5221 tgccagtttc catatgtatg gatcgtcaag tacattcctg taacaaataa aacaagaaca
     5281 agcataccaa taaaaataga tggctttttt ttaagcatat cgtcgtcccc ttatcagaag
     5341 ataaaggaag atagccccac cgatgattcc aacgatcaca ctgactggta tttcataagg
     5401 aaaaatcaac acgcgagcga caagatcgca aaatactaag aacaaactac ctgctaaagc
     5461 agttacgcca attgttttgt gcacttgatc tccatatatt ctagagacaa gattcggaat
     5521 gatcactccg ataaaaggaa tgcttcctac catgatcaac atgactgcac tagccaatga
     5581 tactaagcca atgcctaaaa actgcatctt ctggtaatct attcccagat ttactgcaaa
     5641 cgattcgccc agaccaatga tcgtaaatcg gtaagcaaat agccaaacca agagcaacaa
     5701 tggaacaaca gcatacaata actcataatt tcctcgtatc acagtcgcaa aattcccttg
     5761 aagccatgaa gtcatatttt gtaccaactg gaattgataa gcaaaaaaag tagcaactga
     5821 accaatgata ttccctaaca tgactccaat caacggaagc atcaattgat ttttctggag
     5881 gaacaatcgc gtaagggata aaaaaagcaa tgttcctgca aaagcaaagc aaaatgctgt
     5941 caaggatcgg acaatcaagg atgcaccagg taggaaaatc atagccacta aaatacctaa
     6001 acgcgcacta tccatcgtgc ccgcagtcgt tggtgaaaca aatttatttt gggtcaaatg
     6061 ttgcatgatc aacccacaaa tactactggt cgctcccaca aggatcaaac aaatcgttcg
     6121 tggcaaacga gtcactagca agatttgtaa gctttgccca tctaactgga gcagttctga
     6181 caattgtaca ttcgatactc cgatgaacaa tgaaatacta cttaaaataa ctaataatgc
     6241 tactagtcgt ccgtagcgca tccaatccac ctttctaatt gagaatgatt ttcattctta
     6301 ttttaagtga atcgttgaac aaaagcaacc gctttttcat atgttttagg tattattggg
     6361 aatatgctat aatcgtaaga aagacaaaga gaagaaggag ggtatttttt atggcacaag
     6421 atgatgtaaa aagccatttg gataagggac tttatggtac acctttagtg aaccctgaag
     6481 aacagcataa atatttaggg acattcaggg aacgctgcta tcttagtatg actgttgctg
     6541 aaatgatcca accaaaaaac aaagaaaact ttttaaaaga actcaaaaaa catccagatg
     6601 cttccatact cttgaatggg gctctacccc tttctgtcca aaaccaatat atccagctag
     6661 caacgaaaaa caatagccgt ttcactgtag tcaacgatta cgtcactgca aatcctgagg
     6721 aattcggatt gctcttaaca gcaaaagaag cagtaaatga acctgtgatt gatatcgaaa
     6781 aaaaataccc agaagaaaac tcttcgccag ctgaaaaaga aaaaccaaaa aagaaaaaaa
     6841 gcttctggga tcgtttattt taaaacgaaa aaacacataa atttttacat gcaaaaaaag
     6901 cttttgatca gattgacatc aaataggaca atctgtcaaa agctttttct tttaaaatac
     6961 ttcaggatat aacaatttca atacattcat cgtcaatctt ctgccttttc ctgcaaaagg
     7021 ataaacatgc atatgcatgg ctggattgaa atttgcttcg atgatcccat atgctttttt
     7081 atcagttgta ggatcgattt ctttatctgg tataatcaaa tcgataccac taatcttagc
     7141 tcctagtgct tctaccgcag aaacggcgat ttttttgtaa gcttcagaaa attcatcagt
     7201 catatcgatc gaatcaccac ctgtactgat atttgagttc tcccttagat aaacaatttg
     7261 attggcttgg ggaactgatt cgatcgtcaa cccttgttct ttcaacatca attgttctaa
     7321 ttcacctaat tggatcaatt ctaaaggtgc acgatgattc gttccacgca aagggtcact
     7381 atttttttct tcaacaagtt ctttcactgt tcggatactg tcaccaataa cattagcagg
     7441 gactcgcaac atgatggctt ggacttctcc gtcgatcaca aagaaacgat attccgttcc
     7501 cggcataaat tcttctacta aaaccgaact gtcttcacga aaagcaatgg ctaaacctgc
     7561 ttgataatct tccagactag ctccttcctt gaaaatcgtg atacctaacc cgtaattggt
     7621 tgatttaggt ttgatcacaa atgcctgctc ggcaaatctc ggataagctt ttaccgcttc
     7681 ttccatggat gaaaattctg cgcctcctgg tacccggaac ccagcttctt ttaagacttt
     7741 tttcgttact gttttgtttt ccatgataag tgggacgata tagctgtcct tacttgtcat
     7801 gtttgcattt ttcacatatt ctacatggtc ttggaattgc agacgcaaaa attgatccga
     7861 ctcatctaat actttgactt ggacaccttt ttggatggca tcgaacataa atatctgagt
     7921 agaaagttcc atttcgcgaa aaccggccaa ctgataggga cgttcatggc tttctttata
     7981 atattgatgt cccaatgcca cagcaacttc ttgctgactc gatagctgtg cttcttgata
     8041 gagtttcgct gctaacgttt gttcaggatg atccatttga gtcaatgctt cctctactaa
     8101 ataaagagaa tccaaccaat ccaattcaac cagcatttgc ttcattcctt caagaatttc
     8161 tctaccttct tgatgaaatt ctgtttgatc tgatggttgt tctagtgcta ctttgttatt
     8221 tcgagtcgta ccttctgcta cccattggtc acagtcttct ttttcttctg tccataacat
     8281 gtacatcagg aataattgta agaaccgaac ttgctctgga ttgataccca atcttgcata
     8341 aggattcaaa tcgatattcc gcaattcaat ataacgaaca cctgttgttg ctaaatctgc
     8401 gactttcttt ccgcctcgga aacgaagcgg tgtataaaat tctttctcct ccgaaagttt
     8461 cccttcttcg atcattcgct cgatatctgc taaatactgt ttcatagaag cataggaaac
     8521 tttcacattt ggatgattcg tatagcccag cgcactgttg cgaatactgc gaacaggttc
     8581 ttgcggatgt gattcatcta aaaagtagtt cttctcactc attggtgaag caccgaataa
     8641 ataagtgatc atccagcgat agcgcataaa gtttctcgct gttttcaaat aaagttctgt
     8701 tttgaattcg gaaaaatctt gaaattcttc ctgatggctg aacaatgttc ttagcaactc
     8761 atcgccaaat tcaaaattga aatgaatacc gcttaccatc tgttttcgct tcccgtattt
     8821 ttttgctaaa taacgtcgat acaagacatc ttcgaaattt tttaattttg caataatgat
     8881 ctcttcgtct ttttccggta aggcaggtgg catacttaat ggccagatca tctcttcttt
     8941 cggtatagaa cgagcagtca catcataaac agcagcgaga tactgaaata attcgggaat
     9001 agaatcggta acaggggtga tcatctctgt ttgtgtttcg ctaaaatctg tttggatata
     9061 ggggtgatag gatcgatcgc caaagattgc tggatgatcg gtttttgcta gatttcctgc
     9121 aagatcaacc cgctgtcctt cccgttctat accaaatcga gcttggtcga taaaagggcg
     9181 cgcattgaca tgcaataata attgcttaaa attcatcatt aagtgacctc caattcatat
     9241 gaatctaatt ataatcaaaa agtctaagaa aaagaacgaa attgtttgag aaccgcttac
     9301 aaataagtat aaaaatgaag gcatcaaaaa cacagctatg ttaaaaacaa tcattcaaac
     9361 aaggagctgc aacttttgtc acagctcctg ctttttagac atgggttatt cttcttttag
     9421 taatcctttg aacaatccaa cgacaaaatc atttggatca aacggctcca agtcatcgat
     9481 tccttcacca agaccgacca atttcactgg taaatgcaat tcattacgga tagcaagtac
     9541 gataccgccc tttgctgtac catctaattt tgtcaaaaca agaccggtca catctgttgt
     9601 ttctttgaat tgttttgctt gaaccatcgc gttttgacca gtggttgcat ctaatacaag
     9661 aagtgtttct tggggtgctt ctggtaattc ccgctggatt actcgtttta ttttttctaa
     9721 ttcgttcatc aagttcactt tattttgcag tcggcctgca gtatcaacta gtaaaacatc
     9781 tgcctgctct gtctttgctc tttccaaagc atcgaatacg acagctgctg gatcgcctcc
     9841 tgcattgcca cgaacaactt caacaccagc gcgttcgccc cagacaacta actggtcgat
     9901 tgctccagcg cggaaggtat ctgctgctgc catcaatact tttttacctt cgtttttgaa
     9961 ctgatgggca agtttaccaa tacttgttgt tttccctaca ccattaacac cgacaaacaa
    10021 aataactgtt agtccgtctt cttggatatt tagttcattt acttcattga ttccttccgc
    10081 ttcatagaga tccacaagtt tctcgatgat cgcattttgg acttctgccg attttttcgc
    10141 atttctgagt ttcacttctt gacgtaatgc ttcggtgatt cgtatcgctg tttcaaaacc
    10201 tacatctgca ccgataagtg tttcttctaa ttcttcaaaa aagtcttcat cgactgttcg
    10261 aaaattggca aacaactcat tcatccgttc accaaatgtt ttacgcgtct tttctaaacc
    10321 cttgtcgtac ttctcctgta cttcaacttc ttctgttttc tcttcgccag taaaagcacg
    10381 cttgatttta tcaaaaaatc ccatttgact ccccctactc taatacaaat ttttggatca
    10441 ctttggctac gccattttct tcattgctgg ctgtcacgaa atctgctgct tctttgacga
    10501 aaggcacagc attctccatc gctacgccta gtccagcata ttggatcatc ggtaaatcat
    10561 tttcctcatc accgatcgcc atgatttctt cttgtttcaa accaagatct tttgccaata
    10621 aagaaatacc ataagctttt gtaacacctt ttggcataaa ttccaaaagc atacttcttg
    10681 ttttgatgat ctcatacatt tcatggaatt ctgctggtat ttctttgatt ttaggatcta
    10741 attcttcttg gtcataagcg attactgcct tattaagcac aaattcatct gtaatatcgc
    10801 ttatatccgc tggttggaat tgcagcagct tattcaacac attgtacaag gattgcttcc
    10861 ttggggcact aggcagctgt aaaaccacat tgtcagacaa aacatctagt ggcagatcca
    10921 attgctgagc cagtttgtat aagcgttgga tatctgatac ttccatcact ttcttttcca
    10981 tgatttcacc agtatcattt ttttgtacca aaccgccgtt gaaagtgatg ctgtagtcac
    11041 cttcatctac cagtcctaat tcttgcagat aatgcgccat cgcagctaag gggcgtcctg
    11101 tacatagaac gatcttgacc ccttgctgtt ttgcttgtgc taatgcttgt ttattctcat
    11161 ctgaaatcag cttttgttca tttaataatg taccgtccaa atcgattgct actaatttga
    11221 tcattttcgt tcctacactt tcgtttcgtt gattttcgcc tcttcattga tatcttccat
    11281 ccgtacagaa acgatttttg atacaccgga ttcctgcatc gtcactccgt acagtacatc
    11341 tgctgcgacc atcgttcctt tgcggtgtgt gactacgata aattgtgtgt catcttggaa
    11401 atcgctcaag taacgaccaa aacgtttcac gttggcttca tctaacgctg cttctacctc
    11461 atctaagata caaaacggaa caggacagac acggataatg gaaaagagca acgcgatggc
    11521 tgtaagtgct cgttctcctc cagaaagcaa acttagactt tgcagttttt tgccaggagg
    11581 ttgtacttca atctcaatac ctgttttcag caaatcagtt ggttccgtca gtactaattc
    11641 agctttaccg ccgccaaaca tatttggaaa gacaattttg aattcttgac ggatagcttc
    11701 aaatacttct ttgaatcttg tccgcacttc atcatccatc tcatccatcg tttcaaacaa
    11761 ttggtttttc gctgctaaca gatcatctcg ctgtgttgct aagaatgtat gtctttcact
    11821 gacttgttcg tattgttcga ttgaatttaa gtttactggt cccagttttt caatctgttc
    11881 ttttaaggat gaaacctttg ttctactgtc ttcgatatcg gttgtttctt gatagtcttg
    11941 ggaagctttc tcaaatgtca gctgatattc tgactgcaga taggtcaaat gattatctaa
    12001 aatcatttca gctcggtctt tttggacttc taatttggat tgttccgaca gtcgtgcttt
    12061 ttgctcacga ttacgctctg ccaagactgc ttcaagctta tcgatctcct tttgccttct
    12121 atctcgctgc tctttggctt ttgccaactc ggcttttaat gtttctcgct gagcagataa
    12181 ttcgttaatt tgtttttcca aactttcttc tgtgacttca tgatcagaaa agtctgctgt
    12241 caatgtcgcc aactgctttt ctatcgcttc ttgacgttcg gttgcctctg ctttttggac
    12301 tcgggcaccg cggagctgga tctgcagatg attaaactgc tctttcaaga cagcaagatc
    12361 tgcttgttct tgtgcttttt gactttgtac ttgtgctctt ctggcttcca tctggtcgct
    12421 ttcttgactt aacgatttga tttcttcgtc gattttttgt cgttgcgatt caagatctgt
    12481 ttgtttgtct ttcaattcgt tcgtttgctt ttcgtaatct tcgataaact gctgcagttc
    12541 acgtgtctca aaagttgaga tttgcttttc tttttcaaaa cgttcaagtt catttatgat
    12601 gttttgtagc tgatttgtcg cttcttgttc ttcaaaacgt aattgttcgc ctcgtgtacg
    12661 caaaacttct tgttcttcgg ctaaacgagc tgtttcttgt tgcagctcct gaactttttt
    12721 ttcttgtgct tggagttgtt tatctgcttc ttcaaattca ctagtcaact gtttcaattc
    12781 ttgattttgt acaaacaaac tgccttggtt tcctcgttta ttcgctccac ctgtcatgga
    12841 tcctccggca ttcatcacat caccttctaa ggaaaccact cgatattgat agcggatcgt
    12901 ttgcgcgatt gcattggcac tagttaagtc tttggctaaa aggatcgttc ctagcaggtt
    12961 ttgaaccaca gtttggattt gatcgggata actgacttgt tcactggcaa tccctataaa
    13021 cccttctaca gctgctgctt gtgtcaatat atgagccggt aattgtcttg gtttgattgt
    13081 cgtcagtgga aggaatgttg ctcttcctcc tctttgctgt ttcaaatacg tgatggcttg
    13141 ccgagcatct ttttcatttt caacgatgac atgctgggct gccccaccta aagctgcttc
    13201 gatagctaac gtgaaatctg caggaacatc gatcagttca gccactgctc cgacaatacc
    13261 cgaaagctgc tgtttatgct gcaagaccaa tcgaacccct tggtaaaaac caaaatagtt
    13321 ttcttggatt tcttgaaggc ttttcttacg agcacgtagc tgctggactt gattcattaa
    13381 ttgatacatt ttaggctgtt cttttgctaa tgcttcttgg aactttttcc cgttttgttg
    13441 gatcatttct aacttctctt ttgtttcagt taaagatgat tttagctgcg cctgcttttg
    13501 tgtcaattct tctttttgta agatcaatcg gtctactgat gcttctactt ccgattgctt
    13561 ggctaacgtc tgcttgcttt ttgctgtttc ttgtatatat tgacgttcta gatacttcag
    13621 ttcgtttcct acagctgctt gttcttgcat caaatcaaca tattgatctc ttaattctgc
    13681 caataattct ttcgttgatt tttggtattt ttctaattct tgctgtgttt ttatgagatt
    13741 tgcttcagct ttttggatct ctgtttcttt ttctgctgct gctttcatca agctttcttg
    13801 aagcttttca aaatgtttaa cctttttttg tgcttctgct aatgaagttt gatattcttg
    13861 cgagcttttt tgtgtatgct ttgtccgctc ctgcaaaaca tctttttgtc cttctgtctg
    13921 cttcagtttt tccgaaagat ctaataatac ttgctgattt ttttcgatca gacgatcggc
    13981 ttgcgcattt tctttacgct gcttcgccaa aatggattct tgttcttgga tcgactcaga
    14041 tagtttgcct aattctagat tgaatttcgc aagctgtgct tgtttgttgt cccaatcttt
    14101 ttttgctgtc ttgatttcag caaccatcaa agagacatcg gtttgagtca gtgtttcttt
    14161 tagccgtaaa aactcctttg ctgcctcact ctgggcggcc aaaggagtta actgttcttc
    14221 caattcgtgg atgatgtctt ggacgcggct gaggttgtct tctgtttcaa aaagcttctg
    14281 ttctgctttc tttttccgct gcttgtattt caagacacca gctgcttctt caaagatccc
    14341 acgacggtct tccggtttac tactgaaaat cgcttctact tttccttgag aaatgattga
    14401 gaacgattct tttcctaatc cagaatctaa gaacaattct tggatatctt ttaatctgca
    14461 gctttgttta ttgatgaaaa actcgctttc cccagtccgt cgataacggc gggttacact
    14521 gatctcattg tactccaatg gcagataatg atcactattg tctaaaatca ctgtgacttc
    14581 tgcaatattc agctgcttac gggtatcgga accggcaaag atgatatccg gcatttttcc
    14641 gcctcgcaga cttttagcag attgttctcc taatacccag cggatagcct ctgtaatatt
    14701 gctttttccg ctgccatttg gtccaaccac tgctgtgacg ctattttcaa aatcaatgac
    14761 tgtcttgtct gcaaatgatt taaaaccggc tatttcaatt cgtttcaaat acaaagcttt
    14821 ccctcactta cttttacagt gctgccaatg cattttccgc cgcagcttgt tctgctaatt
    14881 ttttcgattt cccttgtcca gtgccaatca attgatcatc tacataaact tcgatccaaa
    14941 atactcgttc atgagctgga ccttcttcat tgatcaatcg gtattcgatt gatacatcac
    15001 ctgatttttg caagacttct tgtagttttg ttttatgatc catctcatgt gaaaaagcac
    15061 ctgctttgac tttaggaaaa atcacttttt cgatgaatgc atgggtcgtg tcgaatccct
    15121 ggtcaagata taacgcgcct aaaaaagctt cgaataggtc gcaaagcaat gctggtcgcg
    15181 tacgtcctcc tgaattctct tctcccttgc ccaacaaaac atattgatca aagtgacatt
    15241 ctttggcaaa tttcgacaag ctgtcttcgc gaacgatcgc agctcgtgtt tttgtcaatt
    15301 ttccttctgg caaatgagga tataaacgga ataaatactg agaaaccatc agttctaaaa
    15361 cggcatctcc taaaaattca agtcgctcat tatccgataa ttgcagattg cgatgctcat
    15421 tcacatagga tgaatgggta aaagcttgtt caagcaaatt tagatcgtga aaaacgatgt
    15481 tatagttttc ttttagttct tttgtcagct ggttgtccat tttccacatt ccttttatgg
    15541 atattttttc gatacttcct tattatactg gttttttgtc aaatttgaaa tggttcggtc
    15601 aaaaggtaag taaagcttta ataatcctag tgattgacga gaagttgtga aaaattcgtt
    15661 tagtttcgag tatgaagaaa aaattttgtg aaaatggctt tccatatttt tgcataaatt
    15721 tgacttaata ccgagaaact ggactttgaa caccgtttat tggagaagtc atgaaatcag
    15781 cgccttgacc tgaatattag agaaataaac agaaaaatat caaaaaaccg aaaaaggaca
    15841 tcgccctttt tcggtcattt ttagtgatta tgaacgtgaa tctgctgtaa cagaaacatt
    15901 tgcccatggg tttggtacat cataagacca atcccagtct ttgacacggt cgttgactgg
    15961 caatacttca ttacggaaca acgttggaat cgcaaatgct tcttcaaatg catattgttg
    16021 ccatttttga tatgcttctt tttggtactc ttcatcaaat gctttgcttg aactgatatc
    16081 gttgatcaat tttgtatttt cttctgattc ataacgagtg tagttgaacg cagcatttgg
    16141 tccccatagt ccacttggat ttggatcagt tcctgtattc caagcagctt ggtaaacatc
    16201 aatttcagga tcatcgtttt ctaatttatc atagaaagaa ttgaattcga tcagacgacc
    16261 tgttgtgtat tggacatcca aaccaatttc tttccattgt tggatatagt aatctgccaa
    16321 tggttgcgct gtttccccac cggacatcga agcaaagttg attgttagtt tatttccatc
    16381 tttgtcttct cttaaaccat cgtcatccac atctttgtag ccagcatcat ctaatagttt
    16441 tttcgctttg tctagatctt gtgtgaatcc tttcatctca tcatcatggt atgactggaa
    16501 tactggagga atcaatgaag tcgcattgct tctcaaacct gcatagaaac gttcacctac
    16561 tgcattatta tctaatgcat agcccattgc ttgacgtaat gatttatcag ccatttttga
    16621 atctggattg tattccacac tctttgtatc tgcattccat ttacctaact tgaatcctag
    16681 ataagtataa gaagtttgtt cacggcctaa gtttgtatag ccagcaattt ctttataggt
    16741 atcgtaagta tctgttggca tttggaaaat catatcatat aatttagagt tcaatgcttc
    16801 agttgcactt gccatcggta cagatttcat cgtgatcttt ttcaatttag gcgtaccatt
    16861 ccagtagtgc tcgtttggca agtattctac tgattctcct gcaacgatat tactcatgta
    16921 ataagggcca aaagtcactg gatttttacg tacttgatcg cttgattcca tatctttgat
    16981 tgctacacct tctaacgtat gttttggtgc tgcatatgac cagataccac cacccgattg
    17041 aagcatgctt gggtttactt ctttatattc gatttcaact gttttgtcgt ctattttttt
    17101 gattccggag attgtgtcgg cacttccatc atgatattct tccataccta cgatgttacg
    17161 gaaagtgtcg tcataacgga taccagtgta atctttattc ccaatgattt cgtaagggaa
    17221 aatcacatcg tccgccgtta catcttcacc atctgaccat ttgacgttgt cttttacttt
    17281 gattgtcgct tttttcgtat cttcatctag atcaagcgtt gcagctccgt cgtctgtgat
    17341 tctgaaatcg tcatcgtttg caaatagcgg ttcatgagaa ggagccataa aagctgcatc
    17401 atatgaatct tggtaaaact cccactggaa caatccttta aactgactgt ccgttgcgac
    17461 cgcagcttct aattcgccgt cttcgattgc atcatcatta ttttttgttg caattggaaa
    17521 agttaattcc tctttgttat tgccgttgcc tccagagttg tttccagagg tatctgtacc
    17581 tccgcccccg catgctgcaa gaacgacagc agacatcagc gctgcaaatc caaaaatcgt
    17641 tttcttcatt cctatttccc ccttcgcttc tatactagcc taaccgttgg cgcgcatctg
    17701 cagaacgctt gaatgcttgt ccaacataat tgatactcaa catcaaaact aaaataagga
    17761 ttgatgcggg taaccagatc cattgccgat tcactaagac ttctccgtta cttgcataac
    17821 cgatcaatgt acctaaacta ggtacatttg ccggcaagcc gaaacctaag aaagtcaaag
    17881 ttgtctcgat accgatgttt gccgcaaagt tcatcgtcaa attagtaatg attaatgaac
    17941 ttagattcgg catgatttcg cggaacatga ttttaaaatc attggttccc attgtttttg
    18001 aggcactgac ataatctctt cttgcttcag ataatgtctt gcttcggaat aatcgggctt
    18061 tagctaccca ataaaatgca ctcatgatga atataaagga ccagacattg tatctggaaa
    18121 taatcgatac gaagacgata atgatcagca tgatcggtag aatcatgata aaatcaacga
    18181 tccgcatcaa gatgttgtca atgatccctc cgtagtagcc agagatgatc cctaatccaa
    18241 ccccgatgat cgaagtaagg atcgtgatcg caaatccgat cgtaacagag tttctagcac
    18301 ctatgatcaa ttgtcctaat acatcacgtc cgccttcatc tgctcccaga atgaactttt
    18361 gtccttgtgt cgaaactgtt cctggtgcag cgtatttgtc gaagatacta acatacatca
    18421 ctttgtcttg atcggtcagc atcgcaccga taaagatcac taataataaa accactagca
    18481 aacctaatga aaaaatagca attttatctt ttttaaattc tcgagcaatc attcgtatcc
    18541 ccataggagg aatactttct tgaactgctg tattgttttt ttcactcatc gatccattct
    18601 cctttctgat tggttttatt gaatccgaat acgcgggtca acgatactca tgatgatatc
    18661 tgaaagtaat gtccccacta gcgtcgcgat tcctaaaatc aatactaagg atgtgatcac
    18721 ggtatagtcc cgttggccga tggaatcaat aaatagtttt ccgactcccg gataaccaaa
    18781 aatcttttcg ataactacag aaccagcaat caacgaagtg atttcatacc ccatttgaga
    18841 agccatcggc aacgctgcat ttcggaaaat atgtcgactg aatactttat tcgtcggtac
    18901 ccctttggaa cgggctgttc tgacaaaatc gagcgatttc gaatcgatta cttcacttcg
    18961 cagatattgg attgtgacgg cagtcgccaa aaatgcttgg gtaattgatg gtaacagaat
    19021 atatttcaaa cggtctatcc attgagtgat aaatccacct tgcaaaccta gtgtttgtga
    19081 tccacttgtt gggaaccagc ctaaacgata accaaaaaca aatagcatga tcaagccgaa
    19141 gataaataaa ggaacagcaa aactaaagaa gttgtagatt acgacaatct tatccaagat
    19201 tgaattttga taccggccag caagcatccc cagaggcaca gcaatcaaat aagtaaggac
    19261 aactgtcaag atcgatagat ataaagtgtt gatgatccgt tcgccgatca agtcagcaac
    19321 agagcgtttg tataagaaac tttgaccaaa atcgccttgc aaagcatttc cgatccaacg
    19381 gaagtactgg acataccatg ggtcattcaa gccagctgct tgtcgcatct gttcgatcac
    19441 tgccggatcc tgatttggat tgatcaaacc ggtaaatgga tcccccggca tcgcttgggc
    19501 taataagaag atcagaacac ttaaaataat aacttgcggg atcatcaata aaacacgtcg
    19561 cagaatcgtt ttccacatta gcttgcacct ccatctttca acgccacttt gtgtgtagtt
    19621 gtgatcgtac gcaaatcgta gactcgacca gtcgcatcat agtattcttt ttggttttgg
    19681 atatactctt gttctactct tcgtcgattt tctttgtggc tttccctatt ttctacatcg
    19741 atttgcggaa tagctgaaag cagacgtttc gtatagatat gtcgcgggtc attataaatg
    19801 tcttctcttg taccgatttc tacaaatcga cctttgtaca taattgcgat attgtcgcac
    19861 atgtgtttta ctacacctaa atcatgtgaa atgaataaat agctgaggcc gtattcttgc
    19921 tggattcgtt tcatgaaatt caatacttgc gcttgaacag atagatccag agcagataca
    19981 ggttcatcgg ctacgatcag ttttggattg gtagcaacag cacgggctac tcctagacgt
    20041 tgacgttgtc cgcctgaaaa ttcatgagga tatttatata gcgcatcttc cggcatccca
    20101 acgatatcta gcagtccttt tacctttttc ttttcttctt gatcgcttaa ccgttcaaaa
    20161 tttcggatgg gttcagcaat gatatccaac actcgctttt taggattcaa actggacatt
    20221 gaatcttgga agatcatctg cacatccttg ttataaccca tttttttgcg gttgcttcgc
    20281 ttcgttacat cttttccttc atacatgatt tgtccggctg ttaccttttc taatcccaca
    20341 acggcttttc ccgtagtaga ttttccagag ccagactctc ccactaaacc atatgtcttt
    20401 cctttttcga taataaaatc cacaccatct acagcatata catgatccgt tactcgattg
    20461 aagaatccac tgcgaatagg gtaatgaact ttcaggtctt tgattgtgat taattctgtc
    20521 atctacacct ctcctttttc gtctctaaag tggaaatgct tatagcagga gcaacgtacc
    20581 aagtggttcg gtgcgacttc atgaaggata ggctcttctt catgatcgct tgctggtatc
    20641 catggaatac gtggtgcaaa ccgacaacct ttacgaggca tgtttttcag agaaggaacg
    20701 acaccttcga tcacatggag ttctgcatca tgatttcctt cttgtggtat agagttcagt
    20761 aaagagcgtg tataaggatg cttaggatga tcaaacagtt cttttacacc tgctacttca
    20821 acgaactgtc cgccatacat cactgccact cgatcagcca tttctgctac gactcctaag
    20881 tcatgagtga tcaagatgat ccctgttttt gtttcttcct gaaggtcttt cagtaaatca
    20941 agaatctgtg cttggatggt tacatctagg gctgtcgtcg gttcatctgc aatgacgatt
    21001 ggaggtttgc aggcgattgc gattgcgatg atgacacgtt gtctcatacc gcctgatagt
    21061 tcatggggat attggcgtcc aactctcgca ggattaggaa tccctacttg ttctagcaat
    21121 tctagtgcac gagcttgacg ctgttctgca ttcatctttg tgtgatagga aagtccttct
    21181 ttgatctggt cttcgattct catgagagga tttaatgcag acaacggatc ttggaaaatc
    21241 attccgatat catttccgcg gattttatta tagagcgttt cgttcaggtc gattaaattc
    21301 agatcgttat ataaaatctc acctgtaatt tttgtgttat taggatcaag taatcccata
    21361 atcgtagtag ccaaggtact tttcccgcac ccagattccc caacgattgc taaaatctcg
    21421 tttttgtcta aagtaaatga aacgtcatct actgcatcgt aatagtcatc tttgagtcgg
    21481 aatcctgtat gtaggttctg aacttctaat aattggttat cggacaatcg aatacccctc
    21541 tctgcttcct aaatggaagt ttttcttaat aaaaaaggac attacacaga ataaagcgtt
    21601 ttataacaaa ggttattctt atctttgtgt aatgaattat taataattat atagaaaatc
    21661 gctttacttt gcaacataat ttctgtttat cgccagaatt atcagaaaaa tgacttttac
    21721 gtgtcaaaaa gattaaaaaa agaaggataa aaagctgtat gcagcttttt atccttcttt
    21781 gcttttattt gaaattattt aagatggctg ctgatataat ctactgcgcc accgactgtt
    21841 tcaatttgtt cagcgtcttc atctgaaatt tccgtaccga attcatcttc aagctctaaa
    21901 acgaattcca taatactaat tgaatcagct tttaaatcat ctttgatgtt caattcatcc
    21961 gtcactttat cggtatctat ctcaaaatga tttgaaataa ttttcgctac tttgttaaat
    22021 acttcttcgc gagtcaactt tttcacctcc aagaatcata cacttgtcaa ttacctacac
    22081 catggctaat tttactggca tttttcagga atgtccacct ttttttcaat ggaacggatt
    22141 gcttcagata tccaaatact attcttcgct tttttcaaat tgttcgacta attgtccaac
    22201 tacatctgtc tcaagcattg tgtggatttg gcggatcgta tagcgaacag catcggggcc
    22261 tgttgctcca tgagttttaa tgactggtgc tttcaagcca aacaaaacgg caccgccatg
    22321 tttggaataa tccatttctg ctttcaaaga acgtaagccg tcttttaaaa gcatagcgcc
    22381 catttttcct ttgatccctt catttagaat agcagatttt aatagattca tcatattcat
    22441 tgctgttcct tcaatagatt tcaaaacagc gttgcctgta aatccatctg tgaccactac
    22501 atcagccaca ccattgagta gctcacgagc ttctacgttt ccaataaaat tcaagcttgt
    22561 ttcattctga aggagttcat aggctttttt cgtcacttca ctaccttttg ttgcttctgt
    22621 tccgttgttt aagagtgcga cacgaggacg tccgatacct cggactttac gtgcataaaa
    22681 agaacctaaa ataccgtatt gcaacaaatg ttctggtttg ttttctgcgt tagcgccaag
    22741 atccagcata tcgaaaccgg caccttcttt ccctactact ggcaaggtag acatcaagcc
    22801 agggcgttcg atatttttga tacgtcctac gatgaacaac cctgctgcta gtagcgcgcc
    22861 tgtattccct gctgaaaata cagcatctgc ttcaccgttt ttcactgctt gtgcagcaag
    22921 gaccattgat gcagtctttt ttcgtcgaat tgcttttact ggctcatcat cactattgat
    22981 tttttcgtct gtatggataa tcgtgatgtt tttttcattt gttaagtatt tcttgatttc
    23041 tgcttctttt ccgtaaagta agaattctac ttctggaaaa tcttgctgcg ctaaagccac
    23101 gccttctaca attgcttgag gtgcgtgatc tccgcccatt gcatctacgg caattttcat
    23161 tgtttccact cctttttccg tcatcagtat aaagtatagc acagtctgct aatcgaaata
    23221 acgattatcc tgattttcta tttggaggct ttgcgctaaa ggctgatact caggaagcat
    23281 ctgccaatcc tttatctgcc aaagggctgc agcctcttct ctggctacct ccaaaacatt
    23341 tccatccgtc accaagtcag caatcgcaaa ttgaggcaga ccagattgac ggaagccaaa
    23401 tacttcacca ggaccacgta attccagatc tttttcgctt agtacaaaac cattggtggt
    23461 ctctgtcatg attttcatcc gttccacacc tagttcattt ttaggattag caactaagat
    23521 acagtaggaa gcatcacttc cgcgtccaac acgtccacga agttgatgca gctgtgccaa
    23581 tccaaatcga tccgcatcca tgatcagcat gacggtcgcg ttcggcacgt ttacccctac
    23641 ttcaattaca gtagtcgaaa ctaatatctg catctggttg tctttgaagg cttccatgat
    23701 tacttctttt tcctgattct tcattttacc atgtaacaag ccaacttcat attttggtgc
    23761 aaatagttca cgaagttttt catagatttc cactgcattt tttacatcta atgcttctga
    23821 ttcttcaatc agcggacaga tgacatacat ttgatgtcct cttgccagtt cttttttcgt
    23881 ccaatccagt acactgtcca attgaggtgt tcttacccag cgtgtttcga tcgggatacg
    23941 tccagctgga agttcatcaa tgatagatac atccatctca ccatatgctg taatagctaa
    24001 tgttctagga atcggagtcg ctgtcataaa taagacatct ggtcgccagc ctttttcacg
    24061 aagtactttc cgctggttca cgccaaaacg gtgctgctca tccgtaataa ctagacctaa
    24121 attctgaaat tcgactccat cttggatcaa tgcatgtgtg ccgatcacga tgttaatttc
    24181 cccttgctct agtttttcaa ggagctcacg acgttctttt gctttcgttg accccgtaag
    24241 caatgcgatg gttacttcat tgggatcaaa cagctgttgc aagctttcca tatgttgttg
    24301 tgccaagatt tctgtaggca ccatcaacgc accttggaaa cctgctgtaa cggtagcgta
    24361 taacgcaatc gcggcaacca ctgtttttcc gctacctaca tctccctgca aaagtcgctg
    24421 catatgctgc ggactgcgaa gatcccgaca gatttcattc gttacacgtt tttgtgcatt
    24481 tgtcagttca aaaggtagct tttgagtaaa ttctttcaat ttttggacat cataaaggat
    24541 ctccaaacca ttcgtttctg ctttttctgc ttttttcaat ccttgaagac gcatttgaaa
    24601 taaaaagaac tcttcaaaaa cgacacgtcg tttggcttga tggttttctt cgtggtcttt
    24661 tggaaaatgc atacttctta cagcagaagc tcggtcaagc agtcgatatt tctccacaag
    24721 gttgtttggc agattttctt caatcaatgt gccgtattct tgaaaccctt ttttgattag
    24781 atcaactaat gtcgtttgac gaattgattt gttgacgtga tatatcggcg aaaagtcatc
    24841 cattgtttga gaacctaaaa tcttcatccc gttcaatgct ttacgctttg catcccattt
    24901 accgtatacg gcgatttcct ccgataaaat gactttttct tttagataag gttgattaaa
    24961 aaaagaaacg ttgaacacat catgttcttg catcatacga aattgcaatc ggcttttttt
    25021 ataaccaaat cgattcatca caggaggcga gactacgatt cctttcaaag taaccttttc
    25081 ttgatcttgg atctcgttta gatttctttc ctgaatatct tcgtagcgga aaggataata
    25141 agtcagtaag tcttcaatcg tttggatgcc caagctggca agactagctg ctcttttttc
    25201 tccgactcct gccagcatag tgattggatc atctaaagaa cgcataaatt tttcctccct
    25261 cccttaacaa aaaaaggact tggtcagcga tcatacctga tcactaaccg aaggcctttt
    25321 atgaatgaat actgtgttag aaagatattc tgacacagaa attattcagc agaaaataga
    25381 taaggataga caggctgatc tccttggtgg atctcgattt ccaaatcagg atgtttttct
    25441 gttagtttct cagcaaattc atttgcttgt tcaactgttc cttcatcacc tgccaagatc
    25501 gttacgatct ctgtgtcctc attgatcatt tgttctagtg tacttaacgc tgttgctgtg
    25561 atatctgggt tagagatcag gatttttcca tcgatcatgc ccaaaaagtc tccttctttg
    25621 atctctacac cgtcaattga ggtatctctg atcgcgtgag tgacttgacc gctcacaacg
    25681 ctagacaaca tttctgtcat cgtttctttg ttttcttcta aagaagcttg atcattgaat
    25741 gaaagcatag ctgtcaatcc ttgggaaatc gttcttgaag gaacaactgc tactgggata
    25801 tctgctactt ctgctgcttg atcagctgcc atgaagatgt tcttattgtt tggcaagaca
    25861 atcactttat ctgcgtttac ttcttgaatc gctttaacaa tgtcttccgt acttggattc
    25921 attgtttgcc caccactgat aacataatta gcgcctaaac tttcaaacag ctcttggacg
    25981 cctttaccag cagcgatcgc tacgatacca tacgggatac gtggtgtttc ttttttcgca
    26041 aactcgttca cttcttcatc gtgttccaaa atcgtctcat gctgcaagcg catgttgtcg
    26101 actttgattt tgactaatga accgaatttt tgtccataat tcaagacttc tcctgggttt
    26161 tctgtatgca cgtggacttt gatgatctcg tcatcattga ccacaagtaa agaatctcct
    26221 ataccatcta aatagttacg gaattcttcg taatcgaatg tactatcgac tgtaggtcct
    26281 tctccgattt ttaccatgat ttctgtacag taaccaaaat ggatatcttc tgtcgccatt
    26341 tgaccttgga cactgcgatg atgttctgca ttgaccatat catccatttc tgctggagaa
    26401 ggttcatatg tttcatccgc ttggaattct ccattcaatg cacttaaaaa gccctcataa
    26461 acaaacagca gtccttgccc tccactgtct acgacaccga cttcttttag gactggaagc
    26521 aagtctggag ttttagctaa agcacgcttt gcccctttta caacagctgt cattacttca
    26581 acgacatcat cagtactttt tgctttcttt tctccagctt tcgctgcttc tctagctact
    26641 gtcaaaatcg ttccttctac tggtttcatt actgctttat acgcagtttc aactccatga
    26701 gtgaaggctg cagcaagatc ggaagcattt aatgagacaa catctggaat ttgcttagaa
    26761 aatccacgaa acaattgaga caaaataacg ccggaatttc cgcgcgcacc catcagcaat
    26821 ccttttgaaa gcattgctgc taattctcct actttttctg aggttgaatc tactactgcc
    26881 ttagctccac tagtcataga tagattcata tttgttcccg tatcgccatc tggcacaggg
    26941 aatacattta atgaattgac gtattctgca tttacttgca gacgattcgc acctgcctgg
    27001 accatttcct ggaactggct tgcacttatt tctgttacac tcacctagat aatcctcctt
    27061 cagatcgact gctgagttac cagccagtct cctgcctagt ctggcagtac acgaacacct
    27121 tgtacaaaga cattaactga attggcagtt acgcctaata atgcctctag attgtatttc
    27181 actttttctt ggacgttgcg ggaaacttca gagattttcg taccatagct gataatcgta
    27241 taaacatcta cagcaatacc attatcttct tggcggacaa ctactcctct tgagtaattt
    27301 tctttacgca aaatctcagt aatattatct ttaatttgat ttttgctggc cattcctaca
    27361 acaccgaaca catctgtcgc ggcgccacca acaactgttg caattacatc attggtaatt
    27421 tcaatggttc cagctgacgt ttgaattttt acagccatga atgagcctcc ttaacgggta
    27481 aaaaactccc atttttcttc tatcatattt tatcatagcg caacttgaaa taaaaggcag
    27541 ttacccaaag tactcaaaaa ccttgcaaaa tttcaggtat aaccttgttt aatttacaat
    27601 tattcttctc aattgtcaat tgtatctatg aaaatgtact tgcaaatttc cattctatat
    27661 gatatgttag tctggtatga gctgaattat tctattgctc caaatcaagg caaaggagga
    27721 aattaccatg gcaaaagttt gttactttac aggtcgcaag acaaaaagtg gaaacaaccg
    27781 ttcacacgct atgaactcaa caaaacgtac tgttaaacct aacttacaaa aagttcgcgt
    27841 tatggtcgac ggaaaaccta aaaaagtttg ggtgtcaact cgtgctttga aatcaggaaa
    27901 agttgaacgc gtttaattga atgatacttg gaccgttcag atagtgaacg gttttt
//
LOCUS       DBBGSP010000040        26766 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000040 DBBGSP010000000
VERSION     DBBGSP010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.040"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(26..1957)
                     /locus_tag="ACIZE9_001966"
     CDS             complement(26..1957)
                     /locus_tag="ACIZE9_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGC6093818.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="ACIZE9_001967"
     CDS             complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="ACIZE9_001967"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGC6093819.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2886..3638)
                     /locus_tag="ACIZE9_001968"
     CDS             complement(2886..3638)
                     /locus_tag="ACIZE9_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGC6093820.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3797..4006)
                     /locus_tag="ACIZE9_001969"
     CDS             complement(3797..4006)
                     /locus_tag="ACIZE9_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093821.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4017..5344)
                     /locus_tag="ACIZE9_001970"
                     /pseudo
     CDS             complement(4017..5344)
                     /locus_tag="ACIZE9_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5480..5635
                     /locus_tag="ACIZE9_001971"
     CDS             5480..5635
                     /locus_tag="ACIZE9_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGC6093822.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(5709..6296)
                     /gene="yihA"
                     /locus_tag="ACIZE9_001972"
     CDS             complement(5709..6296)
                     /gene="yihA"
                     /locus_tag="ACIZE9_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGC6093823.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6379..7629)
                     /gene="clpX"
                     /locus_tag="ACIZE9_001973"
     CDS             complement(6379..7629)
                     /gene="clpX"
                     /locus_tag="ACIZE9_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGC6093824.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7876..9165)
                     /gene="tig"
                     /locus_tag="ACIZE9_001974"
     CDS             complement(7876..9165)
                     /gene="tig"
                     /locus_tag="ACIZE9_001974"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGC6093825.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9319..10251)
                     /locus_tag="ACIZE9_001975"
     CDS             complement(9319..10251)
                     /locus_tag="ACIZE9_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093826.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10408..11067)
                     /locus_tag="ACIZE9_001976"
     CDS             complement(10408..11067)
                     /locus_tag="ACIZE9_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HGC6093827.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11070..12095)
                     /gene="sppA"
                     /locus_tag="ACIZE9_001977"
     CDS             complement(11070..12095)
                     /gene="sppA"
                     /locus_tag="ACIZE9_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HGC6093828.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12108..12398)
                     /locus_tag="ACIZE9_001978"
     CDS             complement(12108..12398)
                     /locus_tag="ACIZE9_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093829.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12807..14612
                     /gene="glmS"
                     /locus_tag="ACIZE9_001979"
     CDS             12807..14612
                     /gene="glmS"
                     /locus_tag="ACIZE9_001979"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGC6093830.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14684..16039)
                     /gene="glmM"
                     /locus_tag="ACIZE9_001980"
     CDS             complement(14684..16039)
                     /gene="glmM"
                     /locus_tag="ACIZE9_001980"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGC6093831.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16063..17232)
                     /locus_tag="ACIZE9_001981"
     CDS             complement(16063..17232)
                     /locus_tag="ACIZE9_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGC6093832.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17229..18116)
                     /gene="cdaA"
                     /locus_tag="ACIZE9_001982"
     CDS             complement(17229..18116)
                     /gene="cdaA"
                     /locus_tag="ACIZE9_001982"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGC6093833.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18305..21997)
                     /gene="nifJ"
                     /locus_tag="ACIZE9_001983"
     CDS             complement(18305..21997)
                     /gene="nifJ"
                     /locus_tag="ACIZE9_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HGC6093834.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22196..22717
                     /locus_tag="ACIZE9_001984"
     CDS             22196..22717
                     /locus_tag="ACIZE9_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HGC6093835.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(23416..23973)
                     /locus_tag="ACIZE9_001985"
     CDS             complement(23416..23973)
                     /locus_tag="ACIZE9_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093836.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(24152..24763)
                     /locus_tag="ACIZE9_001986"
     CDS             complement(24152..24763)
                     /locus_tag="ACIZE9_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093837.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(24876..25133)
                     /locus_tag="ACIZE9_001987"
     CDS             complement(24876..25133)
                     /locus_tag="ACIZE9_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093838.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(25730..26008)
                     /locus_tag="ACIZE9_001988"
     CDS             complement(25730..26008)
                     /locus_tag="ACIZE9_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093839.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(26042..26293)
                     /locus_tag="ACIZE9_001989"
     CDS             complement(26042..26293)
                     /locus_tag="ACIZE9_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093840.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         7557 a         5767 c         4584 g         8858 t
ORIGIN      
        1 aaacccagcc tcttcttttt tatttctatg cttctgctac tgcaggagct tttctcaata
       61 aaccataaat cacaccagat acgactgctc cgatagcaat aaacaccaaa tacatgaccg
      121 ggtgactcag taagaataca acgaaaatcc cgccgtgagg agccagtaat ttgattccga
      181 aagctccgac taatccgcca gttaaagcag aaccaataat aaaacttgga atggcacgaa
      241 tcgggtcagc tgctgcaaat ggaatcgatc cttccgtgac aaacgatagt cccatcacga
      301 tgttcgtcaa accagcatct tgatctgttt tgctgaattt attcttaaac aaacgtgtag
      361 caacgaaaat tgccaatgga ggtaccattc ctccagccat aacagaagcc atcacgacac
      421 ttccgccagt tgcaacagtc gtagctaaag ttgctgtacc aaacacataa gcggctttgt
      481 tgattggacc gcctaaatct gccgccatca ttccagctaa taatgcacca agtaaagcag
      541 cattcgaacc actcatactt gtcaagaaac cgttcaatgc atcattgatt gctttcatag
      601 ggacattgac cagcaacatc aagaaaccag taatcagtaa gccaaacact ggataaaaga
      661 ggatcgtttt aattccatcc aatgattttg gtaagttctt gaataattta cgtaaaaata
      721 cgatgacata accagctaag aatccaccaa tcagtgcacc taagaatcct gcaccgcctg
      781 tattagctaa tgcaccagca gcaaatccaa cgatcaaacc agggcggtca ccgatacttg
      841 aagcaataaa tcctgctaat accggcagca tgaaaccaaa tgcagcttgt ccgatttggt
      901 tgaaccagct agcagcttga ttgtaattcc ctagatttga taattgatca tgtggcacgc
      961 caataaattg gtcgatcatg aaagaaagcg caatagcgat tcctccacca ataacgaaag
     1021 gtaacatgtg tgatacgccg ttcatcaaat ctttgtaaat tctttgtccg atagtaccat
     1081 ccgcatttcc ttcttctgaa ctgctttctt ttccatcacc atggaatact ggtgcagtac
     1141 cactaagggc tagattgatc aactcttctg gtttacggat accatcactg acaggacgat
     1201 tgatcagttc ttttccgtca aagcgattca tctctacttt tttgtctgct gcaacgatta
     1261 caccttctgc acgggcgatg tcttcagcag tcaatcggtt tttgattcct tctgaaccgt
     1321 tcgtttcgac tttgatctcc acacccattt ctttcgcttt tttcttcaaa gcatcttctg
     1381 ccatgtaagt gtgagcgatc cctgttggac aagctgtaac ggcaacaacg aattttcttt
     1441 ctggatgagc agaagcttct gcagcttgtg tttcttgttc tgctttttct tctgcttctt
     1501 tttgctcttc agctgtttgg aacaagtctt ggacttcttc tggtgtattt gcttctttta
     1561 attttcctac gaaatctgca tcaatcagca atcgagatag tgctgctaat gcttgcaaat
     1621 gtgtgtcgtt tgcgccttct ggagctgcga tcatgaaaaa cagataagtt ggctgtccgt
     1681 ctaaggcttc ataatctact cctttttggc tttttgcgaa taaaactgtt gcttctttaa
     1741 ctgcactgtt tttcgcgtga ggcatggcga ttccatcacc aagacctgta gaagtttgtg
     1801 cttcgcgggc tagaattcct tctttatatg tttcgatatc ggaaatccgg ccggcatcaa
     1861 acattttttg gaccatttca tcgattgcgc cttttttatc agtcgcttgc aaatccatga
     1921 tcatcgcttc tttgaccatt aaatccttga tattcatgat tatcctcctt gaaactaatc
     1981 aatttttgtg atttcaactt ctggcagcaa ctcatcaatc aattcgcgag ctgccaagtc
     2041 atcagaaaaa gctgttgcgc ttccgcaagc aactccccat ttaaaggctt cgattggatc
     2101 tttcgtacgg ctgtaagccc caataaagcc agcaatcatt gaatcccctg cacctactga
     2161 atttttcaat gggcgaacta atacattcgt tttataagtt ccttgttccg tgaagagcaa
     2221 agcaccgtct ccagccattg agatcagcac attctgtgcc ccttcagcta gtaatttttt
     2281 cccatacgga atgatttctt ctacagattg gaaggttgtg ttgtaaagct cagctaattc
     2341 gtgattgttt ggtttgatca acaacggttt cttaacaagt gcatttttta ggtcatcacc
     2401 tgttgtatca atcacgaaat ctgcaccttt ttctcgaatg atatcaatca gttcttgata
     2461 aaatcctttt cgcaggctag ctggcgcgct tcctgacaat acgacgatat ctccttgtcc
     2521 tactgttcct aatgcttgct tcaactcatc gatttcttca tctgaaatag atgggcctaa
     2581 gccattgatc tcagtttcag tgtctgattt tagtttgata ttgattcttg tatcttcttt
     2641 tacggttgtg aacaaagact ggatttgttc tttttcaagc cacttcgaaa taaattcgcc
     2701 agtgaaccct cctaaaaacc ctagtgctgt agattgagaa tcgatccgtt tcaaaatacg
     2761 ggaaacattg atcccttttc ctccaggtaa cttgaagtct tccttcattc ggttcaaatc
     2821 gcctagtttt aacccatcta cgcgtacgat ataatcaatt gatggattaa gtgttactgt
     2881 gtaaatcatt gtattgcctc cttaattgtt gtcttttcac ggaattcatt aacgaattct
     2941 aatggacaac gctcggttat gatcgtggct gcttccaaag gtgcaacaga ggtgaaggac
     3001 aactggttga atttggtatg atcaatcaat acaaatgtct cttcggaatt tttcatggct
     3061 aaacgtttaa cagctgcctc ttctggatcc ggagtcgtga atccttgttc aagatgggca
     3121 ccgttcattc ccataaatgc tttattaaaa tgaaaatttt ttagttgttc tatcgcatta
     3181 gatcctaaaa cagcattagt tgccagcttt atcgttccac ctaaaataat ggtagcaagc
     3241 tccaaatcaa ctaaatttgc cgcatgttga acggaatttg tcactactgt gatctgtttt
     3301 ccttgcagaa aaggaatcat ttctaacgta gtagagccag cgtctaaata aatgacatct
     3361 tcgtcattaa tggtttcagc tgccgatttg gcgatttgct gtttttcgtg aacgtttttg
     3421 agtgattttt cactcatatt ctgctcaaaa ttcaataatt gctctttctt agctccgcca
     3481 tgaactcttt ctagaaaccc actattctcc agctcttgta aatcacgtct tatcgttgat
     3541 tcagaagcat tcaaaaggtt tacaagatct tgtgatttca cgattttctg ctgttcaagc
     3601 aagtctagga ttttttgtct gcgttcctct gtaagcattt tcacgatcac ctcaatacaa
     3661 ataatagcat attttttttc tactagcaat ataaatcagt caaaaacgtt cataaaaatt
     3721 ataaatcagt caaaaaaaaa taaaaaacca gtcagaaaga ctggtttttt atttttttgt
     3781 ctatcatcaa gccgttttat cgttttttat tttcgcttct tgtttttttc atataaacag
     3841 aagcaggttt tctttcctta tgaagaagat aataataaag tcccatcccg ccaaacatga
     3901 ccaaaaaacc gatgactgat cgaataggaa aattaggaac aaaaaagaga cagacggata
     3961 ataatgatgc cggaaccatt attcgataat agagttgttt atccattttc ttcacctcat
     4021 attttttgta aagtaatcaa ttgttctaat tctcggtaat ctaaaaattg cacacgcaga
     4081 tgctgctcac ctttcttgac atcgaattgg atacttcgcc gctttttctt tattcgtttg
     4141 aaggtaacat cagagagtct atgtttgatt tcctttaacg gtaattctga cagggattct
     4201 gaaggaacat agattcttaa ggataaaaga tactcttgat atttttcatc tgttacctct
     4261 acttctagat attccctaat ataataacaa taagcttcga ttccattatc caaagcaaca
     4321 gtcggatcga taactttata gcacatcatg cgtgatcgat tctcgtcaac ccaaggaaaa
     4381 tacgcctgag catttagtgt tccgcgaaca cgcctttctt tataatctcc ttgttggata
     4441 tcataacttt ttgttacaaa aaatgaagca ttctttttag gaacaggttg catttgtgca
     4501 ttctgatact ggacagattg gatcgtatgg tcagtgtaaa tgtattcaac gaatggcggt
     4561 ttcaataaac cgacaccatt gtcccaagca agatgatcaa acccaagctg gtccctaaaa
     4621 taggattgaa acatttgatt gtttggcttt tgccagttaa aggggtctcg ataaagctgg
     4681 atacatatga cttcgttttc taattccttc actttttcta cttgttggat gtcgagaaaa
     4741 atcggtttag ggatgatttg atgataatag cgactataat acatttccca acacgaagtg
     4801 aaacataaac cttggtaaaa aagatcgtat cctggaaatt ggttgcaatc gactactact
     4861 tccccgtttt gttgtttcat tttaggtaaa tgttcgattt catccttttt ctcaaacaat
     4921 agccgttgag agatctgttt tgtattgtga tagataaact cgctataagc tcgcatatag
     4981 gcgaacaccc catgagcaat catttttttc tgaatgaagt ctcgaatcaa aaattgcttt
     5041 tctttgaaaa cagagataga caatacattt tttatcaata attgattatc ttccaagcga
     5101 aaactacatt cgttctcgtc atttcctaca actaaccaac tttcgtctct taccgatgct
     5161 agcattattt tttcttgaag ctttcgaaga tcatacggat ccgcttgttg tgtgaaagag
     5221 cggataaatg ttggctggat caacagacgt gtcaaaatag cccaatcgct tatttcctgt
     5281 ttttttcttc ttcatttaag tctgtgagct ggatagtcat caataattta tcttcgccaa
     5341 tcattttctc acctctttca aatcttttta taatttaatt ataaccaatg ataaagaaaa
     5401 actaaaactt tatgtcttag aaaccaattt ggacgattac atgatagact aagtaaaaag
     5461 aaacaaagag gtgtttacaa tggggttgaa atttgaacgt acagataatt tagataaact
     5521 tttcgaatca tttgctgtcg atccggaaaa aacagttgca ccaaaagaag agatcgatcg
     5581 atttctaaaa ccacagccac aaaatgaaaa gaaaaaagac aagaaacaaa agtaagttaa
     5641 gctcaaaaaa agacttacca gccaaacttt tatgaaagag tttgactggt aagtcttttt
     5701 tattcttttt atgattcaat tgcttgttcg attgctgccc acgcttcttc ttttccctgt
     5761 tttgtaacgg aagaaaagag aataaacgtg tcattgcgat caaaatccaa cgcttttttg
     5821 atttcgctct catgcttgtt ccatttacca cgagggatct tatctgcctt agtggcaaca
     5881 acaattacag ggatatcata atacttcaaa aattgataca tctggatatc ttcttgagaa
     5941 ggcttatgac gcaaatctac taaagaaacg accgcacgta gctggtctct agtcgttaaa
     6001 tatgtctcga tcatctttcc ccattttgct cgctcagttt tggatacttt tgcataccca
     6061 tatcccggaa catcgacaaa atgtaatgcg ttctcgatca aataaaaatt caatgtctgg
     6121 gtctttcctg gcttaccgga agtacgggct aaattctttc gatcaatcaa tgtgttgata
     6181 aaagaagatt tccctacatt tgatcgtcct gccagagcta tttctggcaa ttgtgtatct
     6241 ggatattgtt ttggtgccac tgcacttatg ataatttcag cttgatggac tttcatggtc
     6301 tctctcctta acaaggtgat gaataaagca agcggctgtc gcaaaagcca aaatgacttt
     6361 tacggcagcc tcttttcatc aacccgcttt tttctctgaa tctttataga ttactgttgg
     6421 ctcaccagac aattcagctg cttcttttgt gataatcact ttttcgatgt tttcatttga
     6481 agggatatca aacatcacat ccatcatgat ttcttcaatg atggaacgaa gtcctcgagc
     6541 accggtattg cgttcgattg cttttttcgc aatggctctc aacgcttcag gttcgaattc
     6601 aagttcggta ttatctagag aaagaagttt ttgatattgt ttgactagcg catttttcgg
     6661 ctcagtcaag atccgtacca gatcatctgt tgtcaatttc tctaaagctg ccataacagg
     6721 taatcgtccg ataaactcag ggatcaatcc gaattttagt aaatcttcag gaatgatatg
     6781 ctgcatgaca ctttcgtctt cagaaagttt ttggttttgt gtaccaaatc caatcgtctt
     6841 ttcgcccata cgattcttca caatcgtttc gatgccatca aatgcaccac ctacgatgaa
     6901 caatatgttc gtcgtatcaa tctgaataaa ttcttgatgt ggatgtttac gtccgccctg
     6961 aggtggcaca cttgcaacag ttccttctag aattttcagc aaggcttgtt ggacaccttc
     7021 gccggaaacg tcacgagtaa tagatacatt ttcgctttta cgcgcaattt tatcgatctc
     7081 atcaatatag atgatccctt tttctgcaag ttccacattg taatcagcag attgaagcaa
     7141 tttaagcaaa atgttttcta catcttcccc cacataacca gcttctgtca aacttgtcgc
     7201 atctgcgatt gcaaaaggta cattcaatgt ttttgctaat gtttgtgcta aaaatgtttt
     7261 accagaccct gtaggtccga tcaagcagat attgcttttt tgcagttcaa catcatctgt
     7321 gttttcttgt gcttgctgat tgacacgttt atagtgattg tatacggcaa cagctaacga
     7381 gcgttttgcg cgatcttgtc caatcacgta gttattcaat acttcaagaa tttctagtgg
     7441 tttagggact tcagtgaatt cgcgtacagc ttcttcataa aattcttcat caatgatttc
     7501 tttacatagg tcgatacatt cattacagat gtagacccct ggaccagcta cgatcttttt
     7561 cacttcttct tgggttttcc cgcaaaaaga acagcgtacg gtctcattgc tacttggatt
     7621 gtcatacatg gtcttcaccc cttaacttgc aaaaagtatg caagaaacta tcaaagactt
     7681 tacagtcttt tactatcata acatagttta gtaaaaagaa aaagtgttta acaaaggatc
     7741 aactgaccta tacctttgca ttttttactc ttaacaaaaa ataaggaact gtgacaaaat
     7801 cgtgtcacag tcccttattt cgaataaaca attttctaga agtagcttct tcagaaatga
     7861 tttattactt gatttctatt ctttcgcttc tgtcgctgta cctgtgatca attcgattgc
     7921 ttttttcatt gtcacatcat gttccagcat atcttctgtc aacacgcgtt tgatttgttc
     7981 gattggcatg ttgtatgttt ctgataattc ttggatttct gcattgattt cttcttctgt
     8041 tgcttgaaga ttttcagcag ctgcaattgc ttcgatcaca agatttgttc ttgtgcgcat
     8101 ttctgcttca ccttcgaatt gtttatgcaa gtcttcttct gtagaaccag ttaattgata
     8161 gtacatttca ggagagatac cttgacgttg catgttgttc aagaattcgt ccattgaacg
     8221 atgtacttca tcatgaacca tcacgtgtgg caattcaacg atttctgcgt tttcaacagc
     8281 catacggatc gctgcttcat cttttgcatc gtccgctgct ttttcttttg tttctactaa
     8341 ttctttgcga tatttttctt tcaattcgtc taatgttgat acttcgtcat caacatcttt
     8401 tgcgaattcg tcatctaatt caggcacttc ttttgctttt acttcatgga ttgtcacttt
     8461 gaagactgct tcttttccag caagatcttc tgcttgataa tcttctggga aagttacatt
     8521 tacatctaga ctttcacctg atttatgacc aactaattga tcttcaaaac ctggaatgaa
     8581 tgagcctgaa cctaattcaa gtgagtaatt ttcgcctttt ccgccatcaa acgcttcgcc
     8641 atctacaaag ccttcgaagt cgattactac tgtatcgcca ttttcagctg cagcatcttc
     8701 tttgataact aattcagctt gtgcttcttg ttcacgtttg atacgtgcat ccacgtcagc
     8761 atctgttact tcacggtctt gtttttcaac aactagatct ttatattgtc ctaattttac
     8821 ttctggtttc actgttactt cagcagtgat tacccagtct tgaccttttt ccatgctttc
     8881 aacatcgatt tttggttgag aaacaggatc gatgccagct tctttgacag cagcttcata
     8941 agcttctggt aatacagcat tcaatgcatc ttcatataaa gcttcttcac cgtacatacg
     9001 gttgaatact tgacgagaaa ctttcccttt acggaatcca ggtacgttca agcttttttt
     9061 cactttatta aacgcagttg ttaatccttt ttggatttcg tcttgcgcaa tcgtaaattt
     9121 taaaacacca tcattcgtgc cttttttttc aaatgttgca gtcatttaat tccctccgag
     9181 tttagaaatt cattttatac atcaaaaacg tttcatgcat acctttaaat agtacactaa
     9241 ccctttcaaa ttgtaaacat attgaatgga tagaatcctt gtttttcata acatttttat
     9301 ctttttcact gataaaatct aatggaagaa gatcatttgc tgcaaaattt tttctctttt
     9361 ttttaaaaaa tcttgttttt catcttctgt accttcatac atcgtttttc ctgtacacgc
     9421 ctctacagtc agttgaaacc agcgcttcgg gtcttcgatg tatgtatcat agacaggata
     9481 aacaattgca gattgcaacg tgaattcttc ttttaacacg gaactaagca gcgcatcttc
     9541 attcccgtaa cgatctgaaa atacacataa ttgctggtaa cttgcctgct gctgcggctt
     9601 tggcagatct tttggtatga ctttgactaa cttttcttca atcgtcaaat agaaaacagg
     9661 atggcattcg ttcaattgcc taagtgtctc cagtaatttt gcccttgcta aaatatggac
     9721 ctctggcgat acaataagtt tactcgctgt ttggataaac tcatgataag gaagctgttc
     9781 gatctcatca atagacgcaa gctgacgtgc aggttccaac gaaggaagtt cctccgattt
     9841 attgtggagt gccttgatct tctgcctctc catttgtccg gataattctt ctgcaaattg
     9901 gattttttca atgacccgct gctcgaaagc ttcataaaaa tctgtacttg ctatcaattt
     9961 tctagcatat aaaaaatctt gtgtactgat taacaagtca aaataaaatt cagcaaactc
    10021 ctcattttga agatactgtt tttcatgcaa gagtgcttgc ttcaatgctt cttttttctc
    10081 gtccaactcg taaagacaaa aaacaagcag gctattagcc tcaaagcttt ctttcaactc
    10141 gtaagctcgt tgaaataatt cttttgcctg ctgatattgc tggtttgcta gtgcttgttg
    10201 tgccactcgc attaaattct catatttttc tggaaaatca atcggcttca cgcagtgtcc
    10261 tcctcttgct catattcagc tcatgttcaa tagtagcaaa acaaaaaaag catgacaatt
    10321 aaaaataact gaagcaccct ctaaaagcta gattttagat ctgactttta gaaggtgctt
    10381 tcaactgtta ctgcttttta ttgctcatca gctgttgact tcctggttga acgctttgat
    10441 cagattgatc gtaacaacac ttgtattagt gaaaaaatcg cccagatgtt gctttttctg
    10501 attaaagact gctggaagat accctaacat cagcaaagga aattttagaa tgaaccggca
    10561 agcaccttct ctaactaaaa cggttgacca gctaagttct tcttcatcaa agctgatgac
    10621 tcgaatacca aagatcattt tcccaatcgt ttggccatga ttgaatttcg tcaataaaat
    10681 aaaatacgct agataaataa gtaaggctgt gaatccgtag agactcagat aagaatctga
    10741 aaaattaagc caacctagat ttttggcaat accaagtgtt aaacgcgtaa tagctccgat
    10801 acacaaaaga tcgaccaaga aggcaaacat tcggataaaa aaacctgcat agaaatactt
    10861 aggaaaatca tttgcttttg gcggttcatt tcttgtgtcc gtatactttt tccatttacg
    10921 ttgtttcttt ttgatttctt cgggcgtcaa aggctctctt tcaaaagagc tcagtacctt
    10981 ttgggaaaag ttggagtcag gtcctacagc aggctgctgt tgcttatctt tttcttgttc
    11041 cttattttca tttgaaagct ctgacatgct tactcacctc cgtaataata cattgctttt
    11101 ggtgattccg ctgtccctag attctcaaga acggataaga tctgactagt ctcagaaggc
    11161 ttcaatccct ggaattctgc tagtttactt cctaaccatg tactagcaaa cccagatggc
    11221 gtggaagaat attctactag ttccgcatct tcaagctgtt gttcctttcg tatagctttt
    11281 aaagcatctt caggaaatcc caattcatcg actaaaccta cttcttttgc ttggacacca
    11341 tcataaatcc ttccatcagc aatttttttg acttcttctt cagatttatt ccgtccctcg
    11401 ctgacgattg ctacaaaacg actatatgcg ctgtcgatat atgcttgaag caccgcttct
    11461 tcttcttttg tctctggtcg cgttcctgaa cccatatctt tcaacgctcc gcttttaact
    11521 gttgtatctt ccacacccag tttttctaga agtcctgaat aattcaatcc tgacatgatc
    11581 acaccaattg agccggtcac tgtttcttct gttgcaaaga ttttatctgc ttgagcagaa
    11641 atatagtagc caccgctagc tgccatgttt ttcatgctga catacattgg gatatcatgt
    11701 tctttacgaa tcgtatccaa tttcttagcg atttccgcac tttcgtagac accgccacca
    11761 ggagaattta cttctaaaaa gatacctttg actgttggat cttcttcaat cgccttcagt
    11821 tgttccataa aatttttatg attgtaacct tcagaagcaa ataaacctga agaccctccc
    11881 gcagcaatcg ttccatctac tgataatttt acgatttttt gcgtactgtc tccctcttcc
    11941 aacacatttg gagctagttc ttcatcccca tataaccaac tgttcaatcc ctcaatttga
    12001 tcgttttcct gaggcttagt caaactagct gaaactaacg aaaccacaaa taatcctgca
    12061 gcaatcagaa ctgctgccca acgtctttta ttcattcttt ctcctttcta atacaagttt
    12121 tttatgacga tcacagtttc tgactgctca gaagtgtcga accgctctgc tttttcttcc
    12181 cgcgcatacc cggaaaacga ctcttttgtt aattcatctt ctaccgtaaa ctcacgagct
    12241 tgagcaactt ccaaggcatc aggtgcgatt tcttggatgc tatcccagcc agtatctaaa
    12301 aatattttcg tatcatctga tacaccagct gatgcttcga atttggacaa ttgttttttt
    12361 aacattccca gtgtcatgat ctcaattttt gaatccattt ttactcctcc tctatccgat
    12421 tactttctat tgtaccgaac tcctgaaaaa gatgatagat aaaaacccat tattttttga
    12481 cataaaaagg acatttgaca aagaatttga tatataccaa tttatttttt attctttttt
    12541 tgttgacaag aacattcgca aaaggttatg attttaaatg tttccagata aaaaacaaaa
    12601 aggaggatag ttataccttt taggatagcg ccaggtctgt gtaaacagat gacgaggaga
    12661 gggtttatcg aaagattcgg cggatggccc tagggactgc actctacaga aaatccacaa
    12721 aaaatgtctg caaagataaa acaaaaggat tttcctgcag ctggaagcat tcatacgaat
    12781 tcattataga aagtaggatg ttttttatgt gcggaattgt tggaatgatt ggattaaaaa
    12841 atgtaacacc aggattgatt gacggtctag aaaaattaga ataccgtggt tatgattcag
    12901 ctggtatctt tgtctcagat ggcacaactg attatctggt caaagcacaa ggcagaattc
    12961 aaaatttgaa aaacaaaata aatattgata ctacaggaaa tataggtatt ggtcatacac
    13021 gatgggcaac tcacgggcaa ccttctgaag aaaacgccca tccacatact tcccaaagtg
    13081 gacgcttcgt gctcgttcac aacggcgtaa tcgaaaactt tgaagaactt aaaattgctt
    13141 atttagcaaa tgaccacttt attggtgaga ccgatactga gattatcgct catctaattg
    13201 aaactttcgc gaaggatact acaacgcaag aggcgttttt aaaagctttg cgggtcatca
    13261 aaggttctta cgctttcgct ttgattgatc ggacagcacc tgatgttatt tacgtcgcta
    13321 aaaataaaag tccactatta atcggactcg gcgatggatt caatgtgatt gccagcgatg
    13381 caatggctat gcttgctcat acgaaggaat tcgttgagat tgaagatgaa gagatggtta
    13441 ccgtcacatc agaaaaagtt attattcaaa attttgcagg tgacatcgta gaacgttctt
    13501 cattcgaagc acaagtagat gcttcagata tcgagaaagg tacctatcct ttttatatgc
    13561 tgaaagaaat cgacgaacag cctattatca tgcgtcgtat cgctcaaaaa tacgtaacag
    13621 aagacaatcg tgtctctctt gatcaaaagc tggtcgatac attgtctgat agcgatcgaa
    13681 tctatatcgt tgcttgcgga actagttacc atgcggggtt agcaggtaaa cagactttgg
    13741 aaaaattgac acagattcct gttgaggttc atttagccag tgaatttggc tataacacac
    13801 ctcttctttc aaaaaaacca ttctttattt tcttgagtca aagtggcgaa acagcagaca
    13861 gccgccaagt gctggtaaaa atcaaccgtc tcggctaccc ttcacttacg attacaaatg
    13921 ttgctggttc tactctttcg cgggaagcat cctttacact gctattgcat gctggacccg
    13981 aaatcgcagt agcatcaacg aaagcttata ctgcacaaat agctgtacta actttattag
    14041 ccaaagctat cggtgataaa aaagaatttg aaacttctct tgtattcgat atcactcatg
    14101 aattgagttt agttgctaat gcgatggaat cggtcatcgc ccaaaaagat tatttagaag
    14161 agttggcaga agtatatctc agcgatacaa gaaatgcctt ttacattgga cgtggtgctg
    14221 actacaacgt ttctcttgaa gctgctttga aattgaaaga aatcagttat atccaggcag
    14281 aaggttttgc cgctggcgaa ttgaaacatg gaacgattgc tttgatcgaa gaaggaacac
    14341 cagtgatcgg aatcatcagt gaagaagtga ctggtgcgca tactcgagga aacctgaaag
    14401 aagtcgaaag ccgtggcgct aaaacactag ttattgtctc agagggatta gaaaaggaaa
    14461 gtgaccagct ggtgctacca actgtccacc cttatctaac tactctaacc acagtcgtac
    14521 cgactcaatt acttgcatat tacgcaacgc tattacgggg attcgacgtt gacaaaccac
    14581 gtaatttagc gaaatcagtg acagtagaat aataaaagaa caaggaccag tgtcagacat
    14641 ctgacactgg tccttgttct tttatttttt atgaaaatat ctcttaatcc agtccgattt
    14701 cttctttgac tactgccgcg attttatcga catagtaatt aactttctca tcagtaggcg
    14761 cttctgccat cactcgaagt aatggttctg taccggaagg acgaactagg attcttcctt
    14821 ctgatcccat ttcagcttct gcctcttcaa tcactttttt gattgccgga acatccatcg
    14881 caccgttttt atcacttacg cggatattca ctaatttttg cggatagatt gttacctctg
    14941 ctgcaagctc tgataatttc ttacctgtct gtttcatgat attcagtaac tgaattcctg
    15001 aaagcatccc atctccagtt gtgttaaaat ctaagaaaat catgtgccca gactgctcgc
    15061 cgccaaagtt ataatcgttt ttgcgcattt cttctacaac gtaacgatca ccaacttgtg
    15121 taacgacatc tttcaaaccg attccttcca ccgctttgtg gaatcctaag ttactcatga
    15181 cagtcgtaac gatcgtatct tttttcaatc gatttttttc tgccaagtat ttagcacaga
    15241 taaacatgat tttatcaccg tcgacaatgt ttccaagttc atccaccgca ataatacgat
    15301 cgccatcgcc atcgaaagct agtccagcat ctgctccttt ttcaacgacc atctcagcta
    15361 aacgttctgg atgggtagag cctacgccgt cattgatatt taacccgtct ggatttgtgc
    15421 ccattgtata aaaatctgtt tcaagatcgg caaacaaacg attaacactt gttgaagttg
    15481 ctccgtttgc tgcatcgaca caaatggtca aaccggaaag gtcaccgttg atcgtttgta
    15541 caaggaattg agaatatttc aataagcctt ctggaaattc ttctacagtt cccaatcctt
    15601 cagctgatgg acgaggcaat tcatccactt cagcatctaa taatgcttca atttctagct
    15661 cttggtcatc tactagttta aaaccatctg caccgaaaaa tttgattcca ttatcttgtg
    15721 ctggattatg agaagcagaa atcatgaccc ctgcgcttgc tttttgcaaa cgtgtcagat
    15781 aagcaacacc tggtgtagag atcacaccta gctggaacac ttcgataccc accgataaaa
    15841 gtcctgaaat cagcgcttct tctaacattt gacctgagat tcttgtatcc cgccctacta
    15901 acacgcgtgg gcgttttcct tcttcttcat gctggcttag gacataacct ccgcaccgtc
    15961 ccagcttaaa tgcaagttct ggcgtaagtt ccttgttggc ttcaccgcgt acgccgtctg
    16021 ttccaaaata tttacccata gttgtaaaat tactccttta acttaatttt ctgaggaatt
    16081 tgttctgctc atttgtgttg attcgcttgt ttctgatgtt tcttctgtac ttgtggtcga
    16141 gctgcttgtc ccagattccg aactggaaga aatggttgtt gtcgatggtt ccgttcctga
    16201 atcagcagat gaaatacttc tactcgtact tgtattttct tgtgtccgac tgctcgtcga
    16261 agcagagcta ctgcttgacg tttgcaacac gggtgtaatc tccacactaa ctgattcggg
    16321 cttgatactt aacccctctt ctactggtat ttcaatttta cgagttgttc gatgattgat
    16381 acctgagaca ttgatcggta cagcaatact gtcaccgatc gatgcaagca aatcgctaga
    16441 gccgcttact tctgcttcca gttttgaaaa actgaaatca tagctttcta ccccggcagc
    16501 tggtgttcct tgctgtatcc cataaagtcg taccgacttg cttggcttga tcgaatcagc
    16561 tctcactgtt acttgcactg gatcagagac gatacttaat acttcccctg ctgcattcag
    16621 cgcctgtatt gggacctcac tattaatccc atcatctgtg accatcgaag cgtccacatc
    16681 agctactact cgtttgattt ctgccaatgt tttgtcacct gtagtgatag agactttttt
    16741 aggactaacg gaagtatcat caagttcata tccagatggt gtgaacgttg aaggaatcaa
    16801 cgtttccaca tcgaaatctt ttattacctt tttctcaacc gttactgtaa tagtcgatgg
    16861 ttcgatcttt gctgtgacag cactgctcaa attttgaatt tttagcggaa cttcatgtgt
    16921 tccttcgccc agcttagtga tatctgctgt gacgcggaac atccgtgtat cttcgtttgc
    16981 ctctgcattc aactgaactc ggtttgcact ggaaagtttg acagtcactg cattttcata
    17041 tccatggata tagtagcgct ttgaatcata agaaatcttg atcggcaccc ccgtaactgt
    17101 ttgattatac gcttcatttc cagaaagcgt atttggaacg gactggccat ttgcattgaa
    17161 gtacagcgca atactgaaca gcaatgcaat aaaactgtaa agaatgcttg tccgtttctc
    17221 ttttgagatc atttgcgatc ccctccctta gtcataccgt ctaggaaaga ttgaatcacg
    17281 tttttcttgt tttttgtttt ctcttcagca attagttctc tacgcaagat tgccaaatat
    17341 tcttgctggg ataagccagc catcagttca ttatctaacg tgatgctgac gtccccggtt
    17401 tcttcagaga caacgatggt aatcgcgtca ctgacttcgc ttataccgac agctgcccgg
    17461 tgtcgagtcc cgaattcttt agggatcaac atactttctg atagaggaag ataggcgctt
    17521 gctactgcga tctttccttc ttttacaata actgcaccgt catgcagcgg tgtattagga
    17581 ataaagatat tgatcagcag ctccccagtg atatctgcat ctaaagcaat ccctgtctca
    17641 atatactcat ctaatccagt atgacgttcg atagtgatca acgcaccgat ttttcgcttg
    17701 gacatatatt ggatggcttt gtcaaaagac aagatcatct tctcatcttc ctgctgttcg
    17761 ctttttgatt gtttgaaaag cgaactgcgt ccaagatgtt ccagtcctct ccggatttcc
    17821 ggctgaaaaa tcacgatagc agctatcacc ccgtacgtaa tgacttggtt catcagccaa
    17881 gacaaggtgt gcagaccaat gatttccgct acgattcgga taacaataaa aatagctaca
    17941 cctttcagaa gctgaatcgc ttttgtgcct cgcagcagtt ggatcagttt gtatacaaga
    18001 taccagacaa ccagaatatc aagtatgttc accaaaaaat tcagagagaa caagtcaccg
    18061 gaaaacattt gctgccaata gtccaaatta aaaagttccc cgatttgaaa tgacataaaa
    18121 agcctctctt ctcttttgag atttcctctc tagtatatca tatgttttaa ttttagaggc
    18181 tgatatgctc gtatttttct tgagaaaaac gcataatttt caagaaaatt gcaagtatgc
    18241 gttttatttt tctctgcaat aaatattttt aaacttcaga gaattattca ttatattttt
    18301 tctgttattt ttcctttttt tcttttgtag cttgttccat ttttttacgt cgttctgctc
    18361 tggcagctct tctagcagct cttctttctt ctgcttcaag gtccgtcgtt ttttcttttc
    18421 tagtcttaac gggtacatcg atagattcct ctggttcaag tcgtttcttg attttttcta
    18481 attctcccgt cagtgcagca tagttgtaaa aacgtgtttt agcgtcgtgg acagtctttt
    18541 caaataaagc ttttgcaaga tttggatttg cgttatctag cgaggaaaag cgaacttgtt
    18601 tcctcatgaa atcaggcata gcagagaaat caggtttttt gtagtccaaa gtcattgggt
    18661 tcttgttttt ttcgaccatt gtagggttat atcgatataa tgaccaataa ccagaagaaa
    18721 cagcttcttt tgcttcttta agcgattctt tcattccgcc aagcaagcca tgtgtgatac
    18781 aaggcgtata ggcaataatc agagaaggac caggatactt ttctgcttct tcaaatgcct
    18841 tgatcgtttg catttgattg gcacctgaag caatttgcgc cacataaaca tttccatatg
    18901 tcatcgccat cattcctaga tctttctttg aagcatactt tccactagcc gaaaatttag
    18961 cgattgccga agctggtgtt gcttttgagg tttgaccgcc agtattggaa tagacttcgt
    19021 tatccaaaac aaggatattc acgtctgctc cgctggcaag tacatgatcg atcccgccaa
    19081 aaccaatgtc gtaagcccat ccgtctccac caatcatcca ttggctgttt tttacgaata
    19141 gatcctttct cttgtatata tcctccagtt cagggaaaat tgatcgttcg ctttcgatcg
    19201 cagcttgcag ttttgctgct ctttgctgcg ttccttcact ctcaaacatg tgtactaacc
    19261 agtcttccat caattctcgt agttcttctg atacttttgg caatacttct ttgattgaac
    19321 ttgccaaagc ctcgcgacga gtctgtgccg ctagaagcat accataacca aattcagcat
    19381 tatcttccaa taaagaattt gaccatgcag gcccttgacc acattcattg gtcgtataag
    19441 gagaagcagg agaagcaccg ccccaaatag aagaacagcc tgtcgcattc gcgatcatca
    19501 ttcgatcacc gaacatttgt gtcaataatt ttacataagg tgtttcgcca cagcctgagc
    19561 aagcgcccga gaattcaaga agcggttgat tgaattgtgt agacaagaca gtattctttc
    19621 ctttgactgg atttgctttt tgtcttaatg tcattgcaaa agcccaattc acagcttgtt
    19681 ctttctgttc ttcataaggc ttcatcacta aagctttttc ttttgcggga caagcctcta
    19741 cacacagacc acaacctgta cagtcttcca ctgaaacttg gatacggtat tttacgccgt
    19801 ctgcgcctcg catttctctc acgataaatc cttctggcgc ttcttccatt tcctcttcat
    19861 ctgctaaaaa tggacggatg gcagcatgag gacaaacaaa ggcacattca ttacacatcg
    19921 tacagcgatc actaatccac tcaggtactt ctaaagcgac gccccgcttt tccatagaag
    19981 ccgttcctaa aggcatttcg ccagttgtca ttccatttgc tacaagtgta ccaacagaga
    20041 gttgatttcc ttcctgtgca ttcactggtt caagtatttc ttgtatataa ccagtgttcc
    20101 ttttattgat tttttcaggc atctccaacg ttctccaatg gtctgggatc gcgacttgat
    20161 gaagcagttc ggtcgtccga tcgattgctt gtatgttttt ttctacgata gccattgatt
    20221 tatgtccata gcttttcagg gcttcttctt ttagcagcgg aagcacctca tcaaaaggaa
    20281 tgatgtcagc taatttaaaa aaagccgttt ccattgccgt attgatccgg cgtcccaaac
    20341 cgacttcttg ggccaatctc atggcattga tcgtatagaa tctaatgtta ttttcagcca
    20401 agtaacgttt taattttaag ggcagatgcg tttctaattg ttcgtcgctc caaagagtat
    20461 tcaataaaaa aatgccacct ggcttcaatc ctttgaccaa gtcatagcta tgcaggtaag
    20521 ctggtgtgtg acaggcaaca aggtccgcat gctcgacaag atacgctgaa cgtatcggcg
    20581 tatctccaaa acgaagatga gagacagtca gaccgccaga ttttttcgaa tcataataaa
    20641 aatagccttg cgcatattta tcggtgtgat ctccaataat cttgatagct gatttatttg
    20701 ctccaactgt tccgtcagat ccaaatcccc aaaacttggc ctggaatgtt tgcggttctg
    20761 tcaaatccag actttccttt ggttccaaag attgataagt cacatcatcc acgatcccta
    20821 tggtaaaccg ttttttgcgt atgcttgggt cttttttcaa ttcatcaaaa actgctgaga
    20881 tttggtcggg agtcacatct ttagacccca atccgtagcg accaccaata acagccgggc
    20941 gaagttcaga atcatataac gcactttgaa cgtctaataa gagaggttct ccacctgccc
    21001 ctggttcttt acttcgatca agaacagcaa ttgtttttac tgtatgaggc aacttttgca
    21061 cgaatgtttc cactggaaaa ggacgataaa gatggatatt caaaaaacct gttttccgtc
    21121 cgtttgcatt caagtaatca atcgtttgtt caatcgtctg tgcaactgat cccatagaaa
    21181 caatgacttc ttccgcatcg tctgctccgt aataagtcac caagtcataa gaagttcctc
    21241 gtaatcggtt gatctctttc atatattttt gaacgatttc aggtaattta tcataatagg
    21301 ggttgatcgt ttcccgttgt tgaaaatgga tgtctggatt ctggttcgta ccactaacag
    21361 tcggatgatt gggattcatc cctcgtttac gaaatgaagc taatttctcc tgattgatca
    21421 gaggagctaa ttcttcatat tccaaaactt cgattttttg aatctcgtga ctcgtacgga
    21481 atccatcaaa gaaattcaaa aaagggactt ctccttcaat agaagcaaga tgggcaacag
    21541 gtgctaaatc catcacttct tgtacactgc tttcagctaa catagcaaat cctgtttgtc
    21601 ttgcagccat cacgtctccg tgatctccga aaatattcaa cgcatttgtc gtcactgccc
    21661 gactagcaac gtggaaaaca cttggcagta gttccccagc aatcttgtac atattcggta
    21721 tcatcaaaag cagcccttgt gaagcggtat atgtagttgt cagtgcacca gttttcaatg
    21781 atccatggac cacaccagct gctcctgctt cggattgcat ttctactact tttactggtt
    21841 gaccgaatac gttttctttt cctgctgctg accattgatc tactaattca gccatggtcg
    21901 aactgggtgt tattggatat attgcagcaa tctcggtaaa tgcataagaa atatatgcgg
    21961 ctgccgtatt gccatccatt gttttcattt ttcgcatgat tcatcatcct tgttcatatt
    22021 ctctcttatt atctgttcca ttataacgta aaacatgcca tttttttctt ttatttataa
    22081 aaatatttta catgtatcta tttgaattgg tcatctaatt tttagacaaa cagtctaaat
    22141 cgttgccttt ttttgtcaga catgtataaa ctataagcga aagaggtgtt ttaacatgga
    22201 tatatcagtg attgatgcaa cgaaaacaaa tacacaaaaa ggaatccttt atggttcatc
    22261 gaatgctcct aaaaaaatgg tcgaattcat caacttagct tgtccgtatt gccgacaatg
    22321 gtttgaagaa tcttatgagc tattagaaga agcagtccaa agcgggcaat tgcagcgagt
    22381 gatcaaattg ttcgataaag aaaaagaaag cttacagcga gggaacgtga tgcaccggta
    22441 tctcacaatc agcgatggcc aaaaagcgat caaagagatc aaacaaatat tcgatactca
    22501 agacgagtgg aaacatcttt ctctccaaga agtagcggat tttgcagtag ataaactaaa
    22561 gctgacagaa caaaaagacg aacagctgag ccaagctgtc atcaacgaag ctgagcaagc
    22621 acatattcga tttgttccaa ctgtcatctt gggtaaagaa atctttgatg aatctatttc
    22681 aatagaggaa ttaaaagaat tgatccaaac aaaataaaaa aataaggagc gtgggacaaa
    22741 agtaaagaac acttttgtct cacgctctaa acacgtataa acggcggaag cagaagcaac
    22801 tccttcttat ttcttggagt taaacgcttc tgtcccagcc tccttattcc gaataaatgg
    22861 tgtccaaaag cttgcatctg ccagattatc tcatttctta tgacaagcta agcaaattat
    22921 ctccaccaaa taatttattc atatttttga cttgcgcata ctaactaatt cttaaatttt
    22981 catacaaaat ttctcaattt cccttaacga gtaatattta tgtacggtga ttctcactag
    23041 tatcccaatc actttttaag ttatcccgat ttcaattcta cttcaaaaat agttgctttt
    23101 atgtatgctg ttagttgatt agatggtcat ttgttgagct aggtcgttta ttttaaacaa
    23161 gttgtttctt tagcttatac ctatctcgtc taccaaacgc aagatggcaa acacaaatgc
    23221 atacgcatct gtatttgcca ctttgattcg tataaagcta acaactatta actcctctca
    23281 gctaatagtt gctctctttt ttattcagat tcatttttgc tgatcacagc ctagtatttc
    23341 aatggttttg aacactaaac caaattgttc cattacaaca ttcactggct gatgaaatgg
    23401 attagtagat ttcgattatt caaagcgatt ttctattggt ggatcgtgtt cccaactaat
    23461 aagacggatt ccaaacctat cgtacagatc ttctaaacca cttataaatt ttgcacctat
    23521 ttcaggtgtt ttattgcgtg gatattctat tgttacgcca ttaaatggat accaattagg
    23581 attaggctct ctttttttct gtacatctcc catagaatag ttagcacttt ctgggacata
    23641 atatattctt cgaccatcct ctaattcatc taataagata tttcgtgatc gtctatcact
    23701 tgctaaatgt agacgccacg tgcgatacca tgccatgcta cctgcatctg cagaaaatcc
    23761 atcaaataat gcaacaattg tatcttctat cacaatcctt tccccatcta cttcatattc
    23821 taatctaaaa tcaaactccc ctcgggtaat ttctggtctt ggtggcttag gacccaatat
    23881 tattctactt aaaaccgcat tcgttcccag atgaaacaca gctataacaa caataatgat
    23941 taatattttg tttctatttg ataaatttct cattattcgc acatcacctc tacattctca
    24001 catattagtt cgtaatactc ctttaatatc aaaatatcta ctggtcgtaa taatattcgc
    24061 tatgaattcc tactactcgt ataagaaagg ccaaatcatc agcttttact tgctgatgat
    24121 ttggcttgtt tctatttatc gtaattgttt tctaatcacc aaaattgtta acaatcggtt
    24181 cagatatttc ccagttgatt aaggtaattc cgtattgtgt caaaacttct tgcgcttctc
    24241 cgaaattaag tacagttctt atgtatccac tttctcctaa tataaagtct acctctcttt
    24301 taaaaccttc ctcgagattt ctaagggcta tatgtggttt taatgacatt gattgtacat
    24361 tttcccccat ataatattgc gcacttcctc gactaaaata gattcctaga tcgtccccaa
    24421 aaggtagatc ttctctacca ctagctaatc tacttctcca tcttcgttct cttttcatag
    24481 aacctgcgct gaactcacac ccgttaaact cagctatgac agtatcttca attatgttaa
    24541 tctgtccatc tagttcgtat tcaatcctaa atggaaattc tccataggtg atttccggtt
    24601 cgggtatttt aggtgagatt aatgcaaaga aaggaaatat taagcttggc aacatcaaaa
    24661 aaactcctcc tatgatcaca attcccgatg taatccaaaa tataatttgt acaattctca
    24721 ttgatccatt gtattccatt ttattccccc tattactatt catatccgcc tatctatatc
    24781 gatcttccaa tgcagagata attgcttcca taccttgatt ttttactgag ttacctatgc
    24841 gagatatcat tctccactaa ggtgcatcat attgtctatc taacatgatt aattctccaa
    24901 taggtgtata ctcctccaaa aacaacattt aatgcatctc cctcgacaac ataagctacc
    24961 atgtttgctg tatatgtgtt tgagtctaat tcataagcag ataaatttac tgtcgctgga
    25021 ttaaatataa tcgcattcgt atttatagct actgaatttg ctgcttcagc accacctttt
    25081 gaatgtccga tcattgtgat ttcaatagta ggatttacgt ggacagccct caccgtttac
    25141 cctgaccatt atagaaatcg cttacttttt tgaactacgc aacaaaggat acaatgctcc
    25201 taacttcact gtctccattt ttgtccacta aggaatataa aaaataggca ttaattcatt
    25261 taattcggtc acaacacgtt accttttaaa tcattatact gtatctcata cattattatc
    25321 aataaactat tataaaaatg caaaaaatgc tttatcaatc tattttgtaa ttggtcataa
    25381 tatcattgaa atcataccct gtatcgattt ttcctatgaa tctcgtctat ttgtgattga
    25441 cgaaaaagag gcaagacaga cactggaatg gtaattttac ccactatttt gctccaacta
    25501 tttgtaatcg tacccacttt tgaaataccg agatgatcat tttaattgat atgctgattc
    25561 ccaagcaaaa ccccaagaaa ttaaatgctc tatcgcatct agcttcttgg gttttgctta
    25621 tataaattcc aacatttaaa ttttttatgc tgttcggtct cagaaatgcc gtttttgctt
    25681 atatcacaat atcaagatgt caaattattc gtgttgccga tgactttgat taattttttt
    25741 caaattgttt attaagacta atgctgtctt tttgcagata ccaatgttcg aactttttaa
    25801 cattatcata tgatcctgca agttttaact tcttaccatt agatgttatc aaagttataa
    25861 ttaaccttgc ctttttccca ttaggatctt ttattttatg aattttctgc aggtaatctc
    25921 tcctaatggc agctattttt acctcatcag tgctgataaa ccattgatca tccacataca
    25981 tactgcctgt tatgttgtgt ttttccattt cttccgagaa cgaaaagttt aaggctcgtt
    26041 cttacttcca aagttgaatg agtccatgga ttggacttag tgtgagaatt gagaacaaca
    26101 ataagaatcc atatcctccc gcaaacatcc ctaaggctat actgtctctc catccataag
    26161 taggattaga agagaaaaga gtcaccgttt gtaataatat gaaaaggaat aatccagcac
    26221 aaacaccaaa gataacaact ccaaacattg aatttttata caatgaccat ttatttatag
    26281 gcttttcttt cattttactt ccccctactg ttctgttcac acggaatgaa ttcaaagttc
    26341 ataagccctc ctctttgaac atatgaatac gacttgctaa ctatacttta aaaaagcttg
    26401 ttttaagcgg ttataggcga gttgtaatct ctattcatct cattagcaaa taacttgccg
    26461 aaaagtctac tgaaattaaa gcagatagtg gaagaattat ttagccagga tagacactat
    26521 ttgtgaaaca catgtcttta cttttgaaat tctatgatga aaagccttgg aatacagtag
    26581 ctcttaattg gtaatacttt ttccattata aataacctct tttcatttta tatttatccc
    26641 ctctaaaaat aatatctaat ctaatatttt aaacttatat ttccctcgct gtgctaatag
    26701 agcattacta aataaataga aactagaaaa aagcattacg cctgccagaa taaaccaatt
    26761 atttgt
//
LOCUS       DBBGSP010000041        26538 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000041 DBBGSP010000000
VERSION     DBBGSP010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.041"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(99..1229)
                     /locus_tag="ACIZE9_001990"
     CDS             complement(99..1229)
                     /locus_tag="ACIZE9_001990"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGC6093841.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACIZE9_001991"
     CDS             complement(1878..3080)
                     /locus_tag="ACIZE9_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6093842.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACIZE9_001992"
     CDS             complement(3140..3343)
                     /locus_tag="ACIZE9_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HGC6093843.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACIZE9_001993"
     CDS             complement(3485..4552)
                     /locus_tag="ACIZE9_001993"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC6093844.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACIZE9_001994"
     CDS             complement(4610..4717)
                     /locus_tag="ACIZE9_001994"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093845.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACIZE9_001995"
     CDS             4880..5692
                     /locus_tag="ACIZE9_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093846.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6066..6257)
                     /locus_tag="ACIZE9_001996"
     CDS             complement(6066..6257)
                     /locus_tag="ACIZE9_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093847.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
     gene            complement(6502..6732)
                     /locus_tag="ACIZE9_001997"
     CDS             complement(6502..6732)
                     /locus_tag="ACIZE9_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093848.1"
                     /translation="MNFFGDRFFQPYKINRNSIIESCDYKKIARKKKKVSIHFKYFIP
                     ISIAKKVEILYLPLTLASLANVVSILIDNKLR"
     gene            complement(6716..6913)
                     /locus_tag="ACIZE9_001998"
     CDS             complement(6716..6913)
                     /locus_tag="ACIZE9_001998"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HGC6093849.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="ACIZE9_001999"
     CDS             complement(7059..7937)
                     /locus_tag="ACIZE9_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGC6093850.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="ACIZE9_002000"
     CDS             complement(7976..9094)
                     /locus_tag="ACIZE9_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HGC6093851.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="ACIZE9_002001"
     CDS             complement(9091..11190)
                     /locus_tag="ACIZE9_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HGC6093852.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="ACIZE9_002002"
     CDS             complement(11241..12062)
                     /locus_tag="ACIZE9_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC6093853.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="ACIZE9_002003"
     CDS             complement(12059..12868)
                     /locus_tag="ACIZE9_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC6093854.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="ACIZE9_002004"
     CDS             complement(12889..13383)
                     /locus_tag="ACIZE9_002004"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6093855.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13895)
                     /locus_tag="ACIZE9_002005"
     CDS             complement(13395..13895)
                     /locus_tag="ACIZE9_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6093856.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            complement(13960..16656)
                     /locus_tag="ACIZE9_002006"
     CDS             complement(13960..16656)
                     /locus_tag="ACIZE9_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC6093857.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRT
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="ACIZE9_002007"
     CDS             complement(17084..18157)
                     /locus_tag="ACIZE9_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6093858.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="ACIZE9_002008"
     CDS             complement(18154..18981)
                     /locus_tag="ACIZE9_002008"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6093859.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="ACIZE9_002009"
     CDS             complement(18982..19788)
                     /locus_tag="ACIZE9_002009"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6093860.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="ACIZE9_002010"
     CDS             complement(19800..20885)
                     /locus_tag="ACIZE9_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093861.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="ACIZE9_002011"
     CDS             complement(20902..21444)
                     /locus_tag="ACIZE9_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGC6093862.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="ACIZE9_002012"
     CDS             21702..22691
                     /locus_tag="ACIZE9_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HGC6093863.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="ACIZE9_002013"
     CDS             22688..23425
                     /locus_tag="ACIZE9_002013"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGC6093864.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="ACIZE9_002014"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="ACIZE9_002014"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGC6093865.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="ACIZE9_002015"
     CDS             23989..24621
                     /locus_tag="ACIZE9_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGC6093866.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="ACIZE9_002016"
     CDS             24706..25353
                     /locus_tag="ACIZE9_002016"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HGC6093867.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="ACIZE9_002017"
     CDS             25358..26341
                     /locus_tag="ACIZE9_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HGC6093868.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
BASE COUNT         8112 a         5605 c         4501 g         8320 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggta cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatatag gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttgccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccg
//
LOCUS       DBBGSP010000042        25787 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000042 DBBGSP010000000
VERSION     DBBGSP010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.042"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            438..992
                     /locus_tag="ACIZE9_002018"
     CDS             438..992
                     /locus_tag="ACIZE9_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6093869.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(1165..1602)
                     /locus_tag="ACIZE9_002019"
     CDS             complement(1165..1602)
                     /locus_tag="ACIZE9_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6093870.1"
                     /translation="MFSSEENKPLYLDYVNHNLKIIIKENNLKHITLHGFRHTHCSLL
                     FESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFMSSTEEKQGSLQK
                     VKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1650..2597
                     /locus_tag="ACIZE9_002020"
                     /pseudo
     CDS             1650..2597
                     /locus_tag="ACIZE9_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
     gene            2868..3303
                     /locus_tag="ACIZE9_002021"
                     /pseudo
     CDS             2868..3303
                     /locus_tag="ACIZE9_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345965.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
     gene            3319..4152
                     /locus_tag="ACIZE9_002022"
     CDS             3319..4152
                     /locus_tag="ACIZE9_002022"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6093871.1"
                     /translation="MLYFSAIDNADFVFSDPFTAEVLSGIEEQAKNHGYFVLVHNVNS
                     AEDVKTIQRNWRFEGFIVVGVRVKEFLELNNVFDGPVVYIDTHLSKETLRELEQQMNR
                     LFVNTNDYQASTLAVEHLIHYGHEKIAFLSFDYIVGEPSVIQERHQAYIDTLKKYHLT
                     FKSHWIYNNSEFERIYQELAEFTAIVVTGDYLAAKLVKFLKNKNKRVMEQLSIIGFDD
                     ITFAELMDPALTTIRLNPGNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKI
                     K"
     gene            4397..5422
                     /locus_tag="ACIZE9_002023"
     CDS             4397..5422
                     /locus_tag="ACIZE9_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6093872.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5560..5685
                     /locus_tag="ACIZE9_002024"
     CDS             5560..5685
                     /locus_tag="ACIZE9_002024"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093873.1"
                     /translation="MKHFKKIALTGIAVLTGTLLAACGGGDSNSKDGQVTLSYAS"
     gene            5710..6825
                     /locus_tag="ACIZE9_002025"
                     /pseudo
     CDS             5710..6825
                     /locus_tag="ACIZE9_002025"
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
     gene            6908..7804
                     /locus_tag="ACIZE9_002026"
                     /pseudo
     CDS             6908..7804
                     /locus_tag="ACIZE9_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338086.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
     gene            7820..8644
                     /locus_tag="ACIZE9_002027"
     CDS             7820..8644
                     /locus_tag="ACIZE9_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6093874.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8676..9986
                     /locus_tag="ACIZE9_002028"
     CDS             8676..9986
                     /locus_tag="ACIZE9_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HGC6093875.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            10134..11393
                     /locus_tag="ACIZE9_002029"
     CDS             10134..11393
                     /locus_tag="ACIZE9_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC6093876.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11403..12275
                     /locus_tag="ACIZE9_002030"
     CDS             11403..12275
                     /locus_tag="ACIZE9_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6093877.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            12287..13117
                     /locus_tag="ACIZE9_002031"
     CDS             12287..13117
                     /locus_tag="ACIZE9_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6093878.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            13157..15340
                     /locus_tag="ACIZE9_002032"
     CDS             13157..15340
                     /locus_tag="ACIZE9_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGC6093879.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15401..16621
                     /locus_tag="ACIZE9_002033"
     CDS             15401..16621
                     /locus_tag="ACIZE9_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HGC6093880.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16618..18078
                     /gene="gtfA"
                     /locus_tag="ACIZE9_002034"
     CDS             16618..18078
                     /gene="gtfA"
                     /locus_tag="ACIZE9_002034"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGC6093881.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            18155..19261
                     /locus_tag="ACIZE9_002035"
                     /pseudo
     CDS             18155..19261
                     /locus_tag="ACIZE9_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19583..19792
                     /locus_tag="ACIZE9_002036"
     CDS             19583..19792
                     /locus_tag="ACIZE9_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HGC6093882.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMASKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19785..19934
                     /locus_tag="ACIZE9_002037"
     CDS             19785..19934
                     /locus_tag="ACIZE9_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HGC6093883.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            20088..20753
                     /locus_tag="ACIZE9_002038"
     CDS             20088..20753
                     /locus_tag="ACIZE9_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6093884.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(21037..22122)
                     /gene="xerS"
                     /locus_tag="ACIZE9_002039"
     CDS             complement(21037..22122)
                     /gene="xerS"
                     /locus_tag="ACIZE9_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGC6093885.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            22456..22689
                     /locus_tag="ACIZE9_002040"
     CDS             22456..22689
                     /locus_tag="ACIZE9_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HGC6093886.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            22686..23093
                     /locus_tag="ACIZE9_002041"
     CDS             22686..23093
                     /locus_tag="ACIZE9_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGC6093887.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(24230..24748)
                     /locus_tag="ACIZE9_002042"
     CDS             complement(24230..24748)
                     /locus_tag="ACIZE9_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGC6093888.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            25115..25363
                     /locus_tag="ACIZE9_002043"
     CDS             25115..25363
                     /locus_tag="ACIZE9_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093889.1"
                     /translation="MVKLKMLYIGLQHRSFFDCALGKKYYEVKIDDDTFLTAHQMKQL
                     QKRNDQLEENLILKKRLPYSRLARRTIKGQDLPEDHPF"
BASE COUNT         8786 a         3931 c         4794 g         8276 t
ORIGIN      
        1 aattattgac gctcccgaca aaattatgat cttgcgtaaa gttataaaat attaataaaa
       61 atattttatt aatgaaaagc ttggtagcac ggttattcat atgctaattt atttcacttt
      121 atagtaaggg gagttcttag tatattgttc aaacttaaat ttcatataat ttaattatgt
      181 aaattagcta ttctaagaac ttctacggat aactgcccgt ctaaaattta aataagagct
      241 tagaatcttc atataagtaa ggttaatttt tttgtacaaa aaagtcggaa tattctgagt
      301 tactgaaatg atataaaatc ataaactaaa tcccttgatt ttattgactt tcaaaagttt
      361 atatatataa gttaatgatt atggtaaaat atatacataa tcattaactc agaatatttt
      421 taagaaggga aacaatagtg agctataatg tacaaccgtt aaggacaaat gaagagatac
      481 aagattttca gttttggcta agaagaacaa gtaatccgga aagagatagt tttttatttt
      541 tgtttggaat caataatggg ttacgtatgt cagatattat aggattaaaa gttggagata
      601 tacgaggcaa aagtaagcct attattgttg aacataaaac aggtaagcga aaaccgattt
      661 ttatagataa tttgagagaa gaaattttat tatatactga aggtaaagaa gaaaatgatt
      721 ggttatttcc gagtcggcaa caaggtcgac atataacaag ggatcgtgtc tatcagatat
      781 atgcagatat agcagaaaaa ttaggacgag atgatatagg aacacataca ttaagaaaaa
      841 cttttgggta tcactactac aagaaaacta gagacattgc taccttaatg tttattttta
      901 atcatagctc gcaagcaatt acaaaaaggt acattggtat aactgaagat gaaataggag
      961 catcacttcg tggatttaaa ctaggtgtat aatttaaaaa tttttataaa cagtaaagac
     1021 aaagattaaa agctattttt atctagaacg attttatttc ataaagttcg cggaataaaa
     1081 gctggggtta ctggtacttg gtataggttc gtgttatata aactaagtaa ttaaataaca
     1141 tttttaggtt ggaaaaggat gaaattaaaa aaagagaatc aatacggtct caaaaacgca
     1201 aacgctgcgg aataagaaaa atactgataa ctcaacgttt agcagactat ctaataggga
     1261 tagtctgctt ttttcgtttt tgaccatact tttgaccttc tgcaaacttc cttgcttttc
     1321 ctctgtagaa ctcatgaaat ctgcaaaacg aattgccgtt tcctctgtct gctttttcgc
     1381 gatatgggtg tatatatcat ccatagtggt tttaatatct gtatgtccaa gtcgaacata
     1441 cacttctttg acagacgcac cagattcaaa gagcagacta caatgggtat gacgaaaacc
     1501 atgaagtgtg atatgtttta agttattctc tttaatgatg attttcaaat tgtgatttac
     1561 atagtctaaa taaaggggct tattttcttc tgatgaaaac aaaagttgtt caccatcttt
     1621 tataggtttg attctcattt ttagatatta tgcccgcacg tattcatcac atttctattg
     1681 tgaatcgctt tattcgaccg acatttgact tttatcataa tatactcggt ttaaaattac
     1741 taatgaaaac aattaatcaa gacgatcata ccatgtatca cctgtttttt tcagataatc
     1801 accaccgtgt gggaactgaa ctgacttttt ttgaagtaca agaagggaac aaccagtttt
     1861 ttggaaccaa tacgattgaa cgaacgatac taaaagttcc ttccgaagca tcattgcatt
     1921 tttgggaaat atattttgaa acacaaggcg tttgccatta tggaatcgaa tcattttctg
     1981 gacgacctat cttacgtttt gaagggccag atgcaacacg attagcttta gttcccttac
     2041 gcgaatttga agatattgat gattatttcc cgtatgtcac agaccagatc cctacagagc
     2101 atgccatttt aggaattgat gccattcaac tacgcgtaca atattccgat gcgactgaac
     2161 gagagttatt gtcggtaggc tggtagcaca aagaatacgt cagtttcttt tcgggtcatc
     2221 aacgagtgac aatcttagaa aatcaagaca ctcagttcta tcaagaagtt cagattattc
     2281 aagatcgtga gaatccagtt gccattgaag ggattggtag cgtccatcat gttgcgtttg
     2341 gcgtagaaaa taaatctgat ttacaacgca tcgacaaaca attacaagag cgcaatttta
     2401 taaattcagg aataaaagat cgtgaatttt ttgtatcact ttattatcgt gacccaaatc
     2461 aattattgat tgaaattgct acaggggaag gaaacctaga tgcaaaagcg tatgaaaatc
     2521 aaagtccacg ctttgaagaa attcctttat ttttaccgca gtacttaaat ttcattcgtg
     2581 aacaagtgga gcaataatta gctaatcaaa tccatgacga agagtaagag gttgactcat
     2641 aagtcaaaaa ataaagaaaa acgcatcaaa tccattctaa agaatgttga tttgatgcgg
     2701 ttcctatttt tataaactat cattttcgac taataaaact acttatgagt cagcctctct
     2761 ttttttcttg atttttatac ctctttctag gtaaactaaa catctgccaa aaataccgtg
     2821 tctcattgaa acattctcaa ctatttcaaa ataaagggga gtaccaaatg aacgagtata
     2881 ttgaaattat ccacgcaaga gaaacaactt aaaaatgtca gtctcaaaat tcccaaaaat
     2941 aaaattagta tttttaccag cgtatctggt tcaggaaaat catcgattgt ttttgatact
     3001 attacccaag aagctggtcg tcaactgaat gacacctatg atagttttac ccgtttattt
     3061 ttacctaaat acagtcgtcc agaggttgat gagattgata atctttctac ggcgattgtg
     3121 gtcaatcaaa agaagattgg tggcagtgcg cgctcaacgt tagggacgat tactaacatc
     3181 aatgcgttat ttcgtgtgtt gttttcatgt tttgcaacac ctagtttagg atatgcaaat
     3241 gcttattcat ttaatgatcc tagtggaatg tgttctgtct gtcagggaat cggtaagacg
     3301 attgcatttt taataggatt gctttatttt tcggctattg ataatgctga ttttgtattt
     3361 tctgatccat ttaccgcaga agttttgtct ggaattgagg aacaggcaaa gaatcatggt
     3421 tattttgtat tggtgcataa tgttaattca gcagaagatg ttaaaactat tcagagaaat
     3481 tggcgttttg aggggttcat tgttgttggt gtacgtgtaa aagaattttt ggaattaaat
     3541 aacgtttttg atggtcctgt tgtttatatt gatacgcatc tttcaaaaga gacattaaga
     3601 gaacttgaac aacaaatgaa tcgtttattt gtaaatacaa atgattacca agctagtaca
     3661 ttggcagtgg aacatttgat tcattatggt catgagaaaa tagcgtttct ttcttttgac
     3721 tacattgtag gtgaaccaag tgttattcaa gaacgacatc aagcttatat cgatacatta
     3781 aagaaatatc atttaacctt taaatcgcat tggatatata acaactctga atttgagcga
     3841 atttatcaag aattagctga atttactgca attgttgtta ctggagatta tttagcggct
     3901 aaattagtaa aatttttaaa aaataagaat aaacgagtga tggaacaatt atcgattatt
     3961 ggatttgatg atattacttt tgcagaatta atggatcctg cgttgacaac aatacgacta
     4021 aatccaggta acaagggggc gattgctttt caccaactga ttggactggc caaacaagaa
     4081 gaaataaaaa atcaagtact actattagag ggagaattga tttctcgaga ctctgttcac
     4141 aaaatcaaat aaaaaagctc tgtgaaataa gtatagttaa caataaaata tccgaacgat
     4201 agagagaatg aactgtgatc tagcagttcc tcgtcgcaaa ttcactagaa ttagcattat
     4261 ttactctaaa ttgttcggat attttttctt gtttttaatt atgattacag tgcctatttt
     4321 taacgaaatt tgcttatttt caaaatgtat gattatatgt tagtaaacac tttcaaatat
     4381 gaaaagagga gctattatgg taggaattag ggatgttgca aaacgggcgg gtgtgtccat
     4441 tgcaacagta tcgcgcgtgc taaatgagga tccgacactt tcagtaaccg atgaaaccaa
     4501 acgaaagatt gcagaatcgg ttaattttta tcattatgtc aaaaaaagtc ccgttgcaaa
     4561 aaatttaaca aatattgcat taataacgac agtttctgaa gtagatgagt tggaagatcc
     4621 ctattttcga acgattcgca gagggattca agtcgaagca gaacaaagca aagtcaattt
     4681 gaagaaaatt attcgtttgt cagaaacacc gttggagcaa gacgatttgc taaaatgtca
     4741 aggtgtgttg attattgggc aggtgctatc ttctgtgatt gaagaagtat cagcaattaa
     4801 ttcgaatgtc gtagtgattg atgaccctag tattgaagct gaagtagatg cagtttatac
     4861 tgatttaaca aaagcaacga atcagcattt agatcgattg tataaaaaag gacaccgaaa
     4921 cattgcgttt atcggaggag gacgtgttcg tttagatagc caaggaaata aacacgtgtc
     4981 agatgatgat tatcgaaaaa tagcctatga gacgtggatg aaacaaaaag gattagaaaa
     5041 atatagtcaa atttatttag aaggctggac cacacttgac ggaatgcagg cagcagattt
     5101 acttttgaaa aaacatgcta aagataagtt gccgactgct atcatggtag gaaatgatcc
     5161 tattgctgtg ggggtttatc gttcacttca aaaaaatggt ctacatattc cagaagatat
     5221 ttcgattgtg agttttgata atattgaagt tgctgaattt ttaacacctg cattaaatac
     5281 ggtgaatgtg aatacagaag aaattggaaa actagcagtt cgcatggtta atgaacgaat
     5341 aaaagaagtt agaaatgttt cgatcaaagt gattgtttct aataatatta ttgttagaga
     5401 aagtgaaaaa aatatcgatt aaaaaagtaa acatccaaaa aagggtgttt acttttttgt
     5461 ttactaatat ttttagtaaa aaatctcgac aaaacattaa gtaaacagtt atggtgttgt
     5521 taacaaaaag aaaacgcatt caaaacagga ggaattaaga tgaaacattt caaaaaaata
     5581 gctttaacag ggatagctgt tttaactggg acattactcg cagcatgtgg tgggggagat
     5641 agtaattcta aagacgggca agtaacttta agctatgcga gttgagatac tgaccaagct
     5701 ccaggactaa gaaaaatgtt agatgaattt gaaaaacaaa atcctgatat caaagtagaa
     5761 atggagacaa cgccttggga tcaatattgg gttaaattag aagctgcaac aacgggaggt
     5821 aatatgccag atgtagtaac catgcactct agcgaatcct ataaatatat gtcacagaat
     5881 gctttgatgg gacttgatga tgttatcaaa gaaaatgata ttgacatggg aaactttact
     5941 gaaggaattg ctgatttcta tacgcttgaa gacgaactat acgcaatccc taaagatgct
     6001 tctgtagtgg ggctatggta caacaaagaa ttatttgata atgcaggtgt cgattatcca
     6061 gatgaaacat ggacatggga aacactcaga caagctgcaa ttgatttaac agatgaatca
     6121 aaaggcatct atggttttgc atcacatatt ggaacagaga ctggctactg gccatttatt
     6181 tatcaaaatg ggggagaagt atttgccgat gacaatacaa aatcaggttt gaatacccca
     6241 gaagcacaag aagctttagc tttttatcga gatattgcac ttgttgatca tgcttcacca
     6301 acaattacag aattacaaga tcctgataag ttaagtcgtt ttcaatcagg tagattagca
     6361 atgatgattg aaggaaactg gtttgcaccg ggatttttga aaaatgacta tctagttgaa
     6421 aatgttgctt ctgccgtgtt acctaaggga aaagttaatg caacaattac aaatggactt
     6481 ggttgggctg ccagtgcgag tacaaaatac ccagaagaag tgaaaaaact aatggcattt
     6541 ttagctagtg aggacgccaa taaaatccaa gcggaaacgg gggcatcaat cccagcacta
     6601 aaaggctttg aagacgagtg ggctgcttct tcagatacaa ttgatttgag tgcttttgga
     6661 aaaatgttgg agtatggagt ccctcgtcca tacaataaag atggattacg agctgaacaa
     6721 gcagaagttc aaattattaa ccgtattctg tctggtgaag taactgttga agatggaacc
     6781 gctcaaattg aaaaagaagt caatgcgata ttgagcggaa attaaattag ttaattatac
     6841 aatatacagg cgaaaggatt ctatttcgtc tgtatattaa tggatgaata ccaaaaaggg
     6901 ggatattatg aaaaatcgaa tttttggaaa atatcgtaaa gatcaagtga tatggggcta
     6961 tatttttatt tttccaacgg cattaggatt aattttatta aatatatggc cagcaattca
     7021 aacagcaatt ttaagttttc aaaaaacggt agggttcggt gatactgaat gggtcggatt
     7081 aagaaattac caaaaaatgt ttgcagacgg tgaagttttt cagtctttat taaacacatt
     7141 aatttatgca gtggtttcga tacctagtat tgttgtatta tccttgttgg tggcagtttt
     7201 aatgaataga aaagttaaag gattgtcgat ttatcggaca atttattttc taccagtcgt
     7261 tgctgcacca tccgcagtcg caatgatttg gcgctggatg ttcaataatg attatggact
     7321 gattaataac atgttggcta aaataggtct cgatggacca gcatggttaa cggatccatc
     7381 gattgcgatt tattctatta tcattgtagg agtttggagt gctattggtt ataacatggt
     7441 gttattacta gccggcttat aagaaattcc taaagattat tatgaagcag cggaaattga
     7501 tggtgctagt ccaatccagc agtttttcaa cattacgtta ccattagtta caccaacatt
     7561 attttttgta gttgtaacaa cagttatcaa tgctttccaa gtatttgatg ttatttttat
     7621 gatgattact cctaatagta ccgccatgtt taaatcacaa tcattagcct atttattcta
     7681 taaacattca tttattttaa atgacaaggg atatggttcg gcaatcgtta tgttcctttt
     7741 agtgattata ttaattatta ctgcaattca aatgaagttg cagaaaaagt gggtaaacta
     7801 ttaaggaggc tatcaaatta tgaaaaataa atttttttca aatgcgccaa tccatatcat
     7861 gcttatttta ggtggtattg caatggcatt accttttatt tggatgattt taacttcagg
     7921 gaaaacgttg gttgaatcta cccaaattcc acctacaatt ttccctgaga aatttcagct
     7981 aagtaactat caacaagtac ttgatttatt accattcatg gctttttata tcaatacatt
     8041 tttaatggtt gttggacgag tgattggctc ggttttattt tcagcaatgg ctgcatatgc
     8101 ttgtgcgcgt ctaagttttc cagggaaaaa tatccttttc agcttagtac ttattcaaat
     8161 gatgattccc ggttccattt ttattactcc acagtattta ttagcacaaa aattgggtat
     8221 tttaaataca attccagcat taatattacc aggggtagtt agtgcgtttg gtacgttttt
     8281 attaagacaa tttttcttag gtttacctga tgaattggag gaagcggcct atttagaagg
     8341 tgccaatatt tggacgatct ttttcaaaat tatgttgccg cttgctaaat caggattggt
     8401 tgcacttgga atattcacag cgttgtttgc atttaaagat ttaatgtggc cattgattgt
     8461 caatacttca attgataaga tgcctttagc tccgggatta gcaaacttac aaggacaata
     8521 tgccacgaac ttcccacaat taatggcagg ttcgttatta gcaatttggc caatagttgt
     8581 gatattcatc gttttccaaa gaaaattcat tgaaggaatt gctacaacag gtagtaaatt
     8641 ataaaactat taattagtga ttggagagta agtacatgac aaaaattaca tttattggtg
     8701 caggaagtac tatttttgca aaaaacgtat taggcgatgc gatgttaact ccaagtctac
     8761 aagatgcaca tattgcattg tacgatattg atgaaaaacg actaaaagaa tcaaatttaa
     8821 tgcttaaaaa tattaataaa aattcgaatg aaaatcgtgc tgatattgtt tcttattatg
     8881 atcgcaaaga agcgttaaga gaggctgatt ttgttatcaa tgctattcaa gtgggtggtt
     8941 ataaaccttc aacagtgatt gattttgata ttcctaaaaa atatgggttg cgacaaacta
     9001 ttggtgacac catggggatt ggtgggattt ttagaaccct acggacacta ccagtaatgt
     9061 tagactttgc taaagaaatg gaagaagttt gtccaaatgc ttggttattg aactatacaa
     9121 atccgatggc gatgttaacc atgggtgttt taaaagcgac gagtattaag actgttggtt
     9181 tatgtcatag cgttcaagta tgcgtaccag aattgtttga gcatttagga atagccgatc
     9241 aatatgactt aaatgacttt caatggaaaa ttgcaggcat taatcatatg gcattcttgt
     9301 tggaaattac aaaaaatggg gaagatttct atccaacaat tcgtcagtta gctgcagaaa
     9361 aaccaaatcc acatccagat tctgtacgtt ttgaattgtt gaaacgtttt ggttactata
     9421 ttacagaatc aagtgaacac aatgcagaat accatccata ctttattaaa tcaaaatacc
     9481 cagaattgat tgacgaatta gggattccgt tggatgaata cttacgtcgt tgtgaacaac
     9541 aaattaatga ttgggaaagc atgcgagagg acattgtaaa taatggggag ttaacacata
     9601 cgagaagccg tgaatatgct tcatatatca tggattctat tacgacagga actccgtcag
     9661 tgattgcagg aaatgtctta aataaaggct taatcacaaa cttaccgaca gatgtttgtg
     9721 tggaagtacc ttgtttagtc gataaaaatg gcgtgcaacc aacctatgtc ggtgaattgc
     9781 caacacaatt agctgcttta aatcggacga atatcaatgt tcaagaactg acagtagaag
     9841 ccgctttaac actagataaa tcaaaaattt atcaagcagc gtatttagat ccacatctat
     9901 catctgaatt gtctttaaca gatatcaaaa atttagtgga tgatttaatc gaagcacatg
     9961 gggactattt acctgaatat aattaaaaag aagctgaaag agtaaggaat tttcaattcc
    10021 ttactctttt cttagttaaa tttagtaaaa atattgacaa aacacttagt aaacagttac
    10081 attagtgtta acaaaaagaa aacgcattca aattgtataa ggaggagcat aaaatgaagt
    10141 ggtctaaaaa aattatttta gcttgtatag cactaggagc aacgatctct ttgactgctt
    10201 gtggaaaaaa tcaggaagat gcaagcggta aggtagaaat agagtttttt aatcaaaaaa
    10261 aagaaatgac tcaaacgatt caggagattg ctaaagattt tgaagcaaaa aaccctgata
    10321 ttcatgtaaa agttgtggat gtaccgaatg ctggtgaagt aattaaaaca cgtatgcttg
    10381 caggcgatgt accagatgtc attaatcttt atcctcaaag tatagaattg aaagaatggg
    10441 cgaaagctgg ttatttagag gacttaaccg aagaaccgta tttagagaat atcaaaaatg
    10501 gatatgcaca acgttttgct attgaggatc gtgtatatag cataccatta accgctaatg
    10561 tctatggttt ttactataac aaaactgctt ttgaggaaat ggggattcaa gcaccagaaa
    10621 cttgggcaga atttgaaaaa atagtagctg agattaaaga tcaaaacaaa gtaccgtttg
    10681 cgattgcagg agcagaaggc tggactttaa atggttatca ccaactagct atagcgactg
    10741 ctgctggtgg tgaagaggaa gcgaacaatg tttggcgttt ctcagaagtt aatggaatta
    10801 atgctgaaag caaagaaatg caaaaagatt ttaatcgatt agatttgtta agagaaccaa
    10861 aagctttgca aaacaactgg caaggtgccg gttataacga tacagtagtt acttttacaa
    10921 aaggtgatgc gttgattatg ccgaatggtt catgggcaat gccgatgatt cattcacaaa
    10981 atccagattt tgaagtagga acttttcctt ttccagcaga tgaagcaggt caaagtctaa
    11041 cgattggcgc aggagaccta gccttatcag tttctgcaac ttctcaacat aaagaagaag
    11101 ccaaacgttt tgtagaatat atgacaacac ctgaagcgat gcagaaatat tatgatgtag
    11161 atggtgcacc gtgtgctgtt gagggcgtta tcgagaatac tcaggattca ccattaagtg
    11221 gtttaactga acttgctttt actgatcgtc atttagtttg gttagccaaa gattggaata
    11281 gtgaaaatga tttttatacc ttaacaacaa attatttaca caatggcaat caaaaagcca
    11341 tgattaacgc attaaatgct ttctttaatc caatgaaagc tgacggaagg taggaaaata
    11401 aaatgaaaat aaaagaaatt ttaaatcgtt actgggcaat catttttgta gcaattccaa
    11461 ttattttgca gatgattttt ttctactttc caatggttca aggtgctttt tacagtttaa
    11521 ctaattggac tggtctgact tataattttg attttgtggg tttgaacaat tataagattc
    11581 ttttttctga tccgaagttt atcaaatcga ttggcttcac tttaattgtg acgctttgca
    11641 tgattgctgg acaaattggt tttggtattt tgattgcgcg ggcgttgaac gcaaatatta
    11701 aagggaaaac attctttaga gcatggttct tttttccagc ggtcttatcg ggcgtggttg
    11761 tttctttagt atttaaacaa atttttaact atggtttacc aaaaattggt agtatgttag
    11821 gcattgaatt tttacaaacc agtcttttag gaacaacatg gggagcgatt tttgcagtaa
    11881 tttttgtttt actttggcaa ggaattgcca tgccagtcat cattttctta gcgggttttc
    11941 aaagtattcc acaagaaatt attgaagctg ctagaatgga tggggcgaat gataagcaaa
    12001 ttttttggaa tattgaaatc acctacttat taccaagtat ttcaatggta tttattatgg
    12061 cattaaaagg tggcttaaca gcatttgatc aaatttttgc tttaactggt ggtggaccaa
    12121 gcgatgccac aacatctttg gggttacttg tttataatta tgcttttaaa aacaatcagt
    12181 ttggttatgc gaatgctatt gctttagtct tatttatctt aattgggatt gtttcactgg
    12241 cacaattaaa attatcgaaa aaatttgaaa tctaggaggt ttcccaatga aaacatcaaa
    12301 agaaaaaaat atttctaaat acttgctttt attattaggg ggcttcatga ttttagttcc
    12361 cttagtttca acgctattcg gttcatttaa aacaacaccc gatattatga ataatttctt
    12421 tcgttttcct aatccagcga ctttggaaaa tttccgaaga ttgttagcgg atggaattgg
    12481 tcattacttt tggaattcgg caatcatcac aatcattgca gtagttgctg tgacagcaat
    12541 tattcctatg gctgcttatt cactagcaag aaaaatgact cgtgggaaag catacggatt
    12601 gatgtattta tttttaattt taggaatttt tgttcctttc caagtaatta tgattccgat
    12661 taccgttatg atgagtaaaa ttggtttagc aaatatgtgg ggattaatct tactctatct
    12721 cacttatgcc gtaccacaga cactattttt atatgttggt tttattaaac taaatgtgcc
    12781 tatcagtctg gatgaggctg ctgaaattga tggggctagt cactttacaa cttatttcaa
    12841 aattgttttc ccaatgttaa aaccaatgca tgcgacgact attattctta atgctctatg
    12901 gttttggaat gatttcatgc taccattatt aattttaaat cgtgattcta atatgtggac
    12961 actaccattg tttcaatata attatacggg acaatatttt aacgactatg gtccaagttt
    13021 tgcttcctat acagtaggaa ttgtcacgat tacactagtt tatcttgctt tccaaagaag
    13081 tattatagct ggaatgagca atggagcagt gaaataacca ataaattatt ctcattataa
    13141 aggagttcat aaacttatga ttatatttga caatcacaca caaacatttc atttacaaaa
    13201 taaaaaaatt agctatctat taggaatcga agaaaataat tatttaacgc atctttattt
    13261 tggaaaaaag attacgcact attctggtgg gtatcgctac ccccgaacag atcgttcctt
    13321 ctcacccaac aatgcaaatg cgcaagatcg tttattatct ttagacacat taccattaga
    13381 atttccagga tatggacatg gtgattttag agaaccggcg cataatatta aattaggaaa
    13441 cggtagtcgt gtaaatgatt ttcgttatga tagctacgaa attcaaaaag gaaagcccag
    13501 cttagcggga ttgccagcct tatatacgga agatgatgat gaagctgaaa cgctgattat
    13561 tcaattgaaa gacgcgatta gtggattgac tttacagttg ttctacacaa tttatcaaaa
    13621 tcacagtgta attattcgtt ctacgcaatt agtaaataat agtgatgaaa cagtggagat
    13681 taaccgctta gctagtcaat caattgattt tccaaatcgt ccactcgagt taattcattt
    13741 aaatggtacc tgggcaagag aacgtcaaat gactagagaa aaaattcata cagggataaa
    13801 agtattagat agtaaacgcg gatcaagcag ccatcaacaa aatccgtttg ttgctttagt
    13861 agatgccaaa acagatgaat ttcaaggaga ggcatatgga tttaatttag tttatagcgg
    13921 taatcacgaa acggtgattc aaaaagatcc atttgaccaa acacgggtca ttatgggaat
    13981 taattcattt aattttggtt ggcaactaaa aactggcgac tcatttcaaa cgccagaagt
    14041 cgtgatggtt tatagtaatg aaggtctgaa tacgttatca cagacgtatc atgaattgta
    14101 taatcaccgt ttaattcgtg gaaactatcg tttaaaagaa cgtcccacgt taatcaacaa
    14161 ctgggaagca acgtattttg attttaacga agaaaaaatc atgaatattg tcgatgatgc
    14221 gaagaacttg ggcattgaaa tgtttgtttt agatgatggt tggtttggcg gtcgtgaaaa
    14281 tgacttcact tcattaggtg attgggttga aacagaaggc aaacttgctt gtggtttgga
    14341 aaatttagcc aagcaagtgc atgataacgg gatgaaattt gggatttggt ttgaaccgga
    14401 aatgatttct gaagatagtg aactatttcg agcacatcca gattgggcat tgggtattcc
    14461 aggtcgtgac cgctcaatta gtcgaaatca atatgttctt gatttttcaa gacaagatgt
    14521 tcgtgataat atctatcaac aaatgacggc gatttttgat cgtgtaccga ttgattatgt
    14581 gaagtgggat atgaatcgaa atatgacaga agtctattct gtcttgttgg actcaacgat
    14641 gcaaggtgaa gtggctcatc gttatatgtt agggttatat gaatttttag aaaagttaac
    14701 aacgaattat ccaactattt tatttgaaag ttgttcgggt ggaggcggtc gttttgatgc
    14761 aggtttcttg tattacatgc cacaaacttg gacgagcgac aataccgatg ccgtggctcg
    14821 tctgaaaatt caatatggaa ccagcttagt gtatccaatt tcaagtatgg gtgcgcatgt
    14881 ttcagcagtc ccaaatcatc aaacaggaag agaaacgagt ttaactattc gtggcaatgc
    14941 tgcgatggct ggtgtttttg gttatgagct agatctaacg caattaactt ctgaagaaaa
    15001 agcagaaatt aaagaacaag ttgcctttta taaaaagcat cgccaacttt tgcaatatgg
    15061 aactttttat cgcttggaaa gtccgtttga aggcaatgat actgcatgga tgtttgtctc
    15121 aaaagaccaa acagaagcca tggtctttta tttccgagta ttagcagaag ctgcgcatcc
    15181 attagtcaca ttgaaattag caggattagc agaagaagca acttatcaaa tggaagatgt
    15241 aacatttgct ggcgatgaat tgatgaatct cggtttttat attgactcag aactacatgg
    15301 tgattatgcg acacaacgct tttatttgaa acagatatag tagcttgaat ttacaatata
    15361 agtgcaacac caaaagagac tcattccaaa cgaagaaaat atgttttatt tacacgcatt
    15421 tactaaaaag cagcctgatt tgaattggga aaatgaagaa gtacgtgaag aaatctatgc
    15481 aatgattaac tattggttag ataaaggact aggcggattt agaatcgatg cgatattaaa
    15541 catcaaaaaa aaactagagt atggcatctt tgaatctgat ggagaagatg ggttagcctt
    15601 cattgggccc tggattctta atcagtcggg cattgaagtg tggttaaaag aaatgagaga
    15661 gcggacattt aaaccacata atagtatgac ggtagcagaa gccgatgttc ctaatgaacg
    15721 tttagatgaa tatattggtg aagatggcta ttattcgatg gtttttgatt ttagttatac
    15781 ggatattgat gtacctgaaa ctggtgaatg gtttaaagat agccaatgga catggacgga
    15841 tatgcgtacc aatattttta cgaatcaatt agttacgcaa gataaaggtt ggggcgcctt
    15901 atatttagaa aaccacgatc aaccacgttc aattaataaa tatattccag aagaatggat
    15961 caatgattat agtaaaaaaa tgttggcgac gctttttatg ttactaagag gtaccccttt
    16021 tatttatcaa ggacaagaac taggaatgac caacatagaa atggcatcat tagaagattt
    16081 tgatgatgta gctacgcatt ctcagtataa acgggcatta gaatatggat tggcaccaga
    16141 gcaagcattg aaagctgtca ataaacgaag tcgggataat tctcgcacac ctatgcaatg
    16201 gaatacgcaa aaaaatgcca gattctcaac ttctgataat gtatggttaa aagtaaatcc
    16261 taattatcca gaactcaatg cagaagctca gttaaccaat caacagtcgg tattcaatta
    16321 ttatcatcaa ttaattaaat taagaaaaaa tagtgtatac aaagacgtgc taatctacgg
    16381 acaatttcta ccagtgaaag ataaaaatga acatattttg ctttatgaac gccaattaga
    16441 agataaaatc gtattagtta tcttaaacgt tacagcaaca gaacaagaat attatgtaga
    16501 tgaacagtac caacaagtat taatcaataa ttatgaagat gttttattag atcaaagtcg
    16561 aaaattgcgt ttacgaccgt ttgaaagtat tgtattagct aattatggag gacaattatg
    16621 aaaattaaaa acgaagcaat gctcatcacc tatgcagata gtttaggaaa aaacatgggc
    16681 gaattaaaac aagtcttaga caaacattta caaggtgtta ttggtggtgt acatctgttg
    16741 cctttttttc catcgacagg tgatcgaggc tttgcgccga gtgattatac gacagttgat
    16801 ccagctcttg gaacatggga agatgtggaa gcattaggtg aagattatta tttgatgttt
    16861 gattttatga ttaatcacat ttctcgtgaa tcaaaatttt tccaagattt caaaaaaaac
    16921 catgagcagt caccatacaa agaaatgttt atccgtattc atgaattttt cccagaaaat
    16981 cgaccaacac aagaagatat tgatttaatc tacaagcgta aagacaaagc gccgtttcaa
    17041 acggtagaat ttgcggatgg tacgacagaa gaggtttgga atacctttgg ggaagaacaa
    17101 attgatttag atgtgaccaa agaagttgtg aaagaattta ttcgagaaac catcaaagat
    17161 atggcgaacc atggctgttc tttaattcga ttagatgcgt ttgcttatgc gattaaaaaa
    17221 ttagatacca atgatttctt cgtggaacca gatatttggg aacttttaga cgaagtgcgt
    17281 caagaagcag cgaaatatga cgtcgaatta ttaccagaaa tccatgagca ttattccatt
    17341 caaatgaaaa ttgccaatca tgattattat atctatgact tcgccttgcc aatggtcact
    17401 ctgtattcac tttatagtgg aaaatcagaa cgtttagcca attggttgaa aatgagtccg
    17461 atgaagcagt ttacaacatt ggatacgcat gatggaattg gtgttgtgga cgctcgtgat
    17521 ttattaacag atgaagaatt ggattacacc tctgaggaat tgtataaagt cggggcgaat
    17581 gtgaagaagg tctattcaag tgccaattac aataatttag atatttatca aattaacagc
    17641 acctattata gtgcattagg cgataatgac cgtagctatc tgttagcacg tgcgattcaa
    17701 gtatttgcgc cagggattcc acaaatttat tacgttgggt tattagcagg aaaaaatgat
    17761 attgaactgt tggaagcaac gaaagaaggg cgtaatatta atcgtcatta ctatgattta
    17821 gccgaaattg aagaagaagt gcaacggcca gtgattcaac aattatttgc acttttaaaa
    17881 tttagaaatg aatctgcggc gtttgatttg gatggaacga ttgaagtagc aacgccatca
    17941 gaatcagaaa tagtgattac acgtaaaaat aaaaacggta gtgatagtgc aacattaacg
    18001 gctaacttgg atacgaaaga atttatcatt gagtctaaag atataaaaat tttcactagt
    18061 gttgcattaa aattttaacc tattccatag aacaaaaaat cctttatact agcacttgga
    18121 tgacttatcc aagaccaata aaaaggactc atacatggat aagtataaaa caaatacagc
    18181 atttaataaa tggttttctg ccataaaatt aggaaaactt tctgtcaact cccaaaaatg
    18241 tatttttgat tacaattcgt atcgtaaaaa actgtctttt gaagctgtgc tcaagctctt
    18301 tctctacgca gttaatgaag aaaaagaaag tttgcgtgat ttgagtacag ctcttatcga
    18361 ccgatcgctc caactagaaa ccgatgtgtc atcgattagt catacccaat tgtctcgagc
    18421 atttaatgca cttgaaccta aagtgttaga agaaattttt caacaactgt tagaaaaagt
    18481 tcaacatcaa atcaaaccaa ccaagcgaaa tcatctgtat ctgattgatt ccagtacgtt
    18541 ttcgcttagt ttaaaacgtc ataagtgggc gactttccgt caaacaaaat caggtgtcaa
    18601 gttacactta aactattgtt atatggacga tactacgatg tatccaactg attttacctt
    18661 aacaaatgcc catgaacatg atctcaatca actaccagta ttggtgaatc aaccagaggc
    18721 aacttacgtg tttgatcgtg ggtattagga ctttgaaaag atggatcaga tgcattggga
    18781 tggctatttc ttcgtcactc ggattaaaaa aaacaccaaa gttcacgtga tagatactct
    18841 ggaaacatcg ccagaaacag aaattctacg agacgagctg gttcgtttag gatctaaaac
    18901 ctatctaacc gccaatttcc gactagtcac tgttcaagat aagaacggac gtgtgtttca
    18961 atttatcacc aatcgaatgg acgtctcttc aaaagaaatc tctgatatgt atcacgctcg
    19021 ttggcaaatc gaattgtttt tcaagcacat caaacaacac atgaccatta aaaccttctt
    19081 ttctcaaagt gaaaaaggcg tgcagaatca attgatttta acgatgattt ccgctctcct
    19141 cacgtttctc atcaaattgg agacgaaaac ggaaaaatca gtgttccaaa tcaaacgatt
    19201 ctttcgttat ttactgtttc agccctttga atgttgtcta gaaaaattaa ttcccacatg
    19261 agaaaaaaga aatttggctc gttacttttg gttttcagtt gaataacaga taaaaaattt
    19321 tctggaaaaa gtcatcctct gcgtcagcac agtttttttt gacttatttt cagaggaaat
    19381 agttttcaga atattctaaa atgttttatg caacactagt gatatttttt agaattagat
    19441 ttctaatgtg cattttttga gtattaagga gcaagtatac aaagatttat aaagctgatt
    19501 aaatttgaat aaaaatatgc aggaacgcta ctatttttag tagtgttctt ttttatattt
    19561 gaataaaaaa tgtggtggtt aaatggtggt tataacaaaa aatgaattaa tgaaattagg
    19621 ttatgggaag tatcagtctg agagaatcat acgacaggca aaagcaatta tggcttcaaa
    19681 aagctatacc tattacgaaa atagaagatt aggactagta cctgttgaat ctgtagaaga
    19741 agttttaggt atgaagatag aggtagagga ggattttcag aatcatggtt aattttaaaa
    19801 aagataaaaa tgggaaatat cattttactg ctagtttggg attcgacaaa cgaacaggga
    19861 aaagagtaca aaaaaacgta gaggggttaa aacagttaaa gaagaaaaaa agcgtatacc
    19921 gaacttgttt ctaattatgg aaaagaagca gaaacttctc aaagtactat gttgtttgag
    19981 gagttttttt ataaattatt cctaccttat tatcaaggga aagtagaaga aagaacatat
    20041 aaaaatcggt tatctacaat caaaaaaact tttcttattt ctttaaaatg gagttaagag
    20101 aaatacgtcc aattgacatt caaaagtggc aaaataattt attgagcaaa tataaaaatt
    20161 cttatgtaag aaacatgtat gggatttttc agatgtcatt agatcgagca gttgttttgg
    20221 gactacttga aaaaaatcct gcaaaagtta ttggaaatgt gaagaaaagg aaaactacag
    20281 ttgatttttg gacaaaagaa gaatttacaa aagttatttc aactttttat attgatgatt
    20341 tgtaccaaca ttttggtttt atttgtatgt ggttactttt tatgaccgtt atgcgtttgg
    20401 gagaagccac tgcattaact tggaaagata ttgattttga aaataaaaac ttgcgtgtga
    20461 ataaaacact ctattataag agagccaaaa cctatgagtt tgtagaaccc gaaacggctt
    20521 ctagtattcg tacaatcgaa ctagacgaca atacaattac ctttttaaaa gcttggaagg
    20581 agcgtcaagt ttcaatagga ggcatgtcgt ttgtactttc ttataatgga acacctactc
    20641 agaaatatac aatccgtcat attatgagaa gacatgcaac gatcgttggt gttcatataa
    20701 tccgcataca cggattaagg catagtcatg cttctttgct tatatcacaa taaaaagatg
    20761 cacttcgaat taaagaaagg ttaaaacatg ctgatgtaca aacgacttta ggaacttatg
    20821 gtcatttgta tctaaattca ttgagagaga taacaaatga tcccacagat tatatccaaa
    20881 ctaatttttc taaaatcaaa ccgacaccta tttacgataa taaaaaataa atgataaaca
    20941 aaagtaggat cacaccaaaa gaaacacact agaaaaacta taatacaggc ttttctagcg
    21001 tgttgtttct tatttccgcc tatttataca ttatactcat aaagcattta atgcatcgat
    21061 cgtagccgca ttgtctatat gggtatataa agttgttgta ttggtacttg aatgtcccaa
    21121 ttgttgggca gttaatacca atgaatttgt ctgttggtag agtctagtag ctaatgtatg
    21181 acgcagtttg tgagggctga cttgaattct aaagcctttt gaatattttg ctaccatccg
    21241 ttcgattgca ataccggata tacgcttggc ttctccttgg taaattgcta gaaataaagc
    21301 tttttcgttt tctgttactt tatatcgttc tttccgaata gctagataat tagctaaata
    21361 ttccattgcg aatgctgcta tattgacagc atctctttta tttccttttc tagttactac
    21421 cacattattc ttatctaaag ataggtcatc taaattaata tttataacct cggagagtct
    21481 caatccagat cctaaaatca gtgcattgat cgccaggtct ctttctacat ctcgttgata
    21541 atagatcaaa gctcgtttac tcaaagtatt tttatattca ttggcaatat aatctagata
    21601 attttgtgta tccttatcta gaaataattt tttctcaatg gcattggcac gtgcagctaa
    21661 cgtagtttta tctgtgatgg ttgctacttg atccatagga ttattgtcta agtatggttt
    21721 tcctagagga ttattggaac ttttcgaaag atatttaaat agaaccttta atgccgtgat
    21781 atttctattg atagtagaag tagatagacc taagttatta ttatctttga gcttagtttt
    21841 tgttgtctct ttttttacat tttcttttgt gcgacgtttc aaatgagatt tgtacaagtt
    21901 taggtcatag gcagttaact gtcttatcga ggtgatagaa gtatcaggaa cgatagactc
    21961 actcagaagc cattcataaa agagcttata attttttaga tattctaaag tggttcgagg
    22021 tgattgatct ttatcctcac gatcttgaac aaaatctttt atataatcgg gcatatgaag
    22081 tatgattgta tctatttttt gatatatttc tgtatttttc atgtcattca tcctttcaat
    22141 aagtagggga gaagagtatc tctataattg gactatacca attatagaat gttttgtcaa
    22201 ttggtatgct ctaaaattta ttaatttgtt tcaaaaaaag catataaaca ggtatacgtt
    22261 taataattta aaataaatgg tatacataaa tagggaagga aatagaaggg agcaatctaa
    22321 attttttgaa ttttcttaat taattatata gaaagaacaa tctttctata gagttagaca
    22381 tgagagggac tatgcttgat ttaaaatcaa caagcgtata tactgtatat acaaagaaaa
    22441 aggagggaga agactatggc aattaaagaa agaaaattta gggaagtggg gaactcagta
    22501 gtattaacta tttcaaagga gtttcttaaa gaaaatgggt taaatcccgg agatacggtt
    22561 tttttagatg aagaaaaact tcgagcggca attacaaaaa aacaagcctt atctgatgaa
    22621 attgatttag caatatctca agcattaact gaatatgata ctacttttag agagcttgtc
    22681 gataaatgag tattcattac ctagaagcca aagatattat aaaaatgaat gtaatccaaa
    22741 taaaaaaata ctctcctaat gaaccccttg gtgtaaagga tgcgaatgct ttagaaatgt
    22801 gtgtagggca acttcgagcc tcagcttttg gtgaagaggt ttatccttcg atttatgaaa
    22861 aagcagctat cctacttata caattgataa agaaacatcc ttttcacaat gcaaataaac
    22921 gtactgcttt cttagctact tttgtctttt tgaaaatcaa tggacagctt ttagctattg
    22981 atcaaaaaga tgctgtaaat ttagcggtat atattgctac gtatgataag gatttcgatc
    23041 aactaaaata tgaagtgatc aacactataa agacacatac gcagcccatt taaggagtta
    23101 ctgtatgtgt ctttataggg ttattagctg ctatagcgaa ataattgaag taaattacaa
    23161 atagctataa ttcaaatcca actatataga aaacgtaaat tttctatata gttggattaa
    23221 gataacgact atttatttta tcatattttt actataccct atacttttac ttggtatatt
    23281 tatgaataat cgcaaattta cccctatact actagtttgt aagttagatt aataaaaata
    23341 ctaaagttat ttgttctttt attaaataca cctacaactt ataaattgat ggtatttaga
    23401 taacacgaaa gaataaaaat aacagctgat agtaaagttt gttgacgatt gctactcaat
    23461 cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact tatgaaatga aagacctttt
    23521 acatcttgca gaaatcgtta ctgggattaa actaagcaat aaaaactaat gttcccctca
    23581 ttctttgaac ttctactatt tgatttattt attctgataa atgacgattt caccttcagg
    23641 atcttcaaat cccgtataga atttatttaa gatctcttca gtatcagtaa taggataggc
    23701 gataggccac ataccctttg atggttagaa taaactgctc aaaatctgta tcgtatgttg
    23761 gctttagcat attaacaaag gctatctcca aattataaac cataagcgtt gaatcgttct
    23821 taacaatttc aattcttcct aacccaaagt cagaagatat aattaccgga cttgccttac
    23881 ccttcatgtg ggttgttgag attccatatt taaagggaat tgtcggtact atcggcggtc
    23941 tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta gtctcctaag tccctttgta
    24001 gcggatatgg caccataatc tcattttatc gaagtgagtc atggtttatc tgttggccaa
    24061 ccaaaattga tacaatctaa cgatgcaccc tctacggcat tctaggggag tgcacttgca
    24121 ttcacccaat aaaaaccggc agttagcaaa gaacttatgt agtcgtatgt tcttactgtt
    24181 aacatacaag aggtctcctt tccacaattg cttagcagta aacgggaatt tacaaagcta
    24241 atctcttcca ttttcttatc tttgttctaa aagtcccaaa tggagcaact gtatttacat
    24301 gaataaattt atatacttcc catacagccg ttttggttgc ctcgtctgcc cattttcttt
    24361 tgtgtgcagt gaatagatct tcatcactca ttgaatcaat catcatgtta atatcatcaa
    24421 tattacgatt gagaatttcc tctaattctt tcaatggtag atgtgcatag gtatttgtaa
    24481 accacttata taactctcct aactgattcc atttaaattg atcagaaggc gttttaacag
    24541 ataatccatt tctttcatca ttttcccatt ttagaattaa attcgtccaa ccaacttgat
    24601 atgctaaatt ttcagcaggt gttctatcca cttcctcaac tcttttatcc ttcaattctt
    24661 caggaatagt ttcaaattct aaaatatatt tagtataagt cctatttatt tcttttttta
    24721 attcttcttt atttttatat gttctcatta tattacctcc ataaattcct aattgtctcc
    24781 tttaattcat ctataatttc atccacgata ttttaatccg ttctacaatg catatctgat
    24841 atgcattgac tgtctaactc atatgtgaat gatttataaa atatcccaac gtctcatcta
    24901 aagaaatgtt gatcgtcagc aaggagctaa aaaatacgaa tatatttctt ttgtagtaaa
    24961 atcggactgg tttgcatatc attttcttcg taaatatcaa aatcatgtta actactatca
    25021 attactaata aaaactacca ctttaagcgt taagaactgt taagtttagt taagtgagga
    25081 tagttcacaa aatccattgt taaacttcac gaaagtggta aaactcaaaa tgctttatat
    25141 aggattacag catcgctctt tcttcgattg cgcgttgggt aaaaaatatt atgaagtaaa
    25201 aattgacgat gacacgttcc ttacggctca tcagatgaaa cagctacaaa aacgaaatga
    25261 tcaactcgaa gaaaatttaa ttctaaaaaa gcgattgcca tattcacgcc tcgctcgacg
    25321 aactattaaa ggtcaagatt tacctgaaga tcatcctttt taggaaattg aagcttttta
    25381 tgttgcacaa tgcatttata atactacaat gatgttttca ccagatattc ttctagggtg
    25441 cggtgtaatg aaacagatac acttgcaaaa gaaaattcac cgcgaattta ctaaaattat
    25501 gaataattat gttaatcttc cgaaattttt ttccaaaatt aagggatcaa gctggtgtta
    25561 tagattgttt aaggttggca aaaaaataac ttctttttaa acaattatag aaaaccgata
    25621 ctctgttaag ttggttgaca cggtgtcgat ttttatgact ttcttattct gaaacttcac
    25681 taacggacag tacctaaaaa gtctatagta tggacgttta cgagtactat tttatcaaaa
    25741 atgctgctca tttcaactta tatgttttag tgaactaccc ccactta
//
LOCUS       DBBGSP010000043        25348 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000043 DBBGSP010000000
VERSION     DBBGSP010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25348
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.043"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(122..499)
                     /locus_tag="ACIZE9_002044"
     CDS             complement(122..499)
                     /locus_tag="ACIZE9_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093890.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            755..1483
                     /gene="purC"
                     /locus_tag="ACIZE9_002045"
     CDS             755..1483
                     /gene="purC"
                     /locus_tag="ACIZE9_002045"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGC6093891.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1483..1737
                     /gene="purS"
                     /locus_tag="ACIZE9_002046"
     CDS             1483..1737
                     /gene="purS"
                     /locus_tag="ACIZE9_002046"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HGC6093892.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1739..2410
                     /gene="purQ"
                     /locus_tag="ACIZE9_002047"
     CDS             1739..2410
                     /gene="purQ"
                     /locus_tag="ACIZE9_002047"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HGC6093893.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2411..4633
                     /gene="purL"
                     /locus_tag="ACIZE9_002048"
     CDS             2411..4633
                     /gene="purL"
                     /locus_tag="ACIZE9_002048"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HGC6093894.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4618..6057
                     /gene="purF"
                     /locus_tag="ACIZE9_002049"
     CDS             4618..6057
                     /gene="purF"
                     /locus_tag="ACIZE9_002049"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGC6093895.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6080..7132
                     /gene="purM"
                     /locus_tag="ACIZE9_002050"
     CDS             6080..7132
                     /gene="purM"
                     /locus_tag="ACIZE9_002050"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGC6093896.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7129..7707
                     /gene="purN"
                     /locus_tag="ACIZE9_002051"
     CDS             7129..7707
                     /gene="purN"
                     /locus_tag="ACIZE9_002051"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGC6093897.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7704..9239
                     /gene="purH"
                     /locus_tag="ACIZE9_002052"
     CDS             7704..9239
                     /gene="purH"
                     /locus_tag="ACIZE9_002052"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGC6093898.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9255..10529
                     /gene="purD"
                     /locus_tag="ACIZE9_002053"
     CDS             9255..10529
                     /gene="purD"
                     /locus_tag="ACIZE9_002053"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGC6093899.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10651..11565
                     /locus_tag="ACIZE9_002054"
     CDS             10651..11565
                     /locus_tag="ACIZE9_002054"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGC6093900.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11698..13263)
                     /locus_tag="ACIZE9_002055"
     CDS             complement(11698..13263)
                     /locus_tag="ACIZE9_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093901.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13256..14707)
                     /locus_tag="ACIZE9_002056"
     CDS             complement(13256..14707)
                     /locus_tag="ACIZE9_002056"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC6093902.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14721..15737)
                     /locus_tag="ACIZE9_002057"
     CDS             complement(14721..15737)
                     /locus_tag="ACIZE9_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6093903.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15957..17045
                     /gene="chvE"
                     /locus_tag="ACIZE9_002058"
     CDS             15957..17045
                     /gene="chvE"
                     /locus_tag="ACIZE9_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HGC6093904.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17099..18625
                     /gene="mmsA"
                     /locus_tag="ACIZE9_002059"
     CDS             17099..18625
                     /gene="mmsA"
                     /locus_tag="ACIZE9_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC6093905.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18627..19832
                     /gene="mmsB"
                     /locus_tag="ACIZE9_002060"
     CDS             18627..19832
                     /gene="mmsB"
                     /locus_tag="ACIZE9_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HGC6093906.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20089..21066
                     /gene="guaC"
                     /locus_tag="ACIZE9_002061"
     CDS             20089..21066
                     /gene="guaC"
                     /locus_tag="ACIZE9_002061"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGC6093907.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21330..22754
                     /locus_tag="ACIZE9_002062"
     CDS             21330..22754
                     /locus_tag="ACIZE9_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGC6093908.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(22796..23053)
                     /locus_tag="ACIZE9_002063"
     CDS             complement(22796..23053)
                     /locus_tag="ACIZE9_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093909.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            23215..24324
                     /gene="pdhA"
                     /locus_tag="ACIZE9_002064"
     CDS             23215..24324
                     /gene="pdhA"
                     /locus_tag="ACIZE9_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HGC6093910.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24327..25304
                     /locus_tag="ACIZE9_002065"
     CDS             24327..25304
                     /locus_tag="ACIZE9_002065"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGC6093911.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT         8194 a         4316 c         5694 g         7144 t
ORIGIN      
        1 gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc aataatagga
       61 acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa aaatagagga
      121 attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga tgttgcagca
      181 agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg atacgataat
      241 gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct ttgtgttctg
      301 tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct cggcggattt
      361 ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg atcgacagca
      421 aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa agctgacctt
      481 gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa atttttagtt
      541 aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta taagattttc
      601 gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca tatttttgtt
      661 gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa aacgatgtat
      721 ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac ttttgtatga
      781 aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga tagaatattt
      841 agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa aaggagaatt
      901 gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa taaaaaatca
      961 ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa ttatccctct
     1021 ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag gtgttcccga
     1081 aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc agttggatga
     1141 tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg aagaaatcag
     1201 tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat ttgctaaggt
     1261 cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac aaattttgct
     1321 tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga atgaacatat
     1381 ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc aagaagtata
     1441 taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt cgtaaaagta
     1501 tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa aaaagcagtc
     1561 catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt tgagatacaa
     1621 cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga caagctgctt
     1681 gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga agtataacat
     1741 gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt tatgggcagt
     1801 tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct ctttagaagg
     1861 atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga gatgcggtgc
     1921 gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag aagggaaacc
     1981 agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt tgccaggtgt
     2041 actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga aagtcaaccc
     2101 caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc cagttgctca
     2161 tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa aaaataatca
     2221 gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg cagggattac
     2281 gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag tagaagactt
     2341 gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact tcggaaaggt
     2401 gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga aaaaaagaat
     2461 ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag atatcttagg
     2521 aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg aacattgttc
     2581 ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc atgtgttgca
     2641 aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag ttgtcttcaa
     2701 agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg cgacaggagt
     2761 tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt tgctagattc
     2821 attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag aagtagttgc
     2881 aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg aaattgcatt
     2941 tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt tgattgaaca
     3001 caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt atgtaggtgc
     3061 aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat ttaatcaaga
     3121 agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa agctgctgct
     3181 tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta tacaggatat
     3241 gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg gctcaggact
     3301 tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt atgaaatgat
     3361 gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg aagaaaaaat
     3421 ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag taacagacga
     3481 cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag tcgatgcatt
     3541 agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa tcgtagaatt
     3601 tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat tgcttgatct
     3661 gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg attcacaagt
     3721 acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg ttagagggac
     3781 gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt tggatccaaa
     3841 aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta gcggtggtaa
     3901 gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag aagttttttg
     3961 ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag gaactcctgt
     4021 tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct atccaacacc
     4081 aatgattggt atggtcggat tgattgagga tcataaacat atcactactc aggaattcaa
     4141 aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg atggcagtga
     4201 attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg atctatccat
     4261 tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga ttgaaagtgc
     4321 tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt tcaaacatca
     4381 gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag aaactcaatc
     4441 aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa tgatgggaga
     4501 tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt cagcaactga
     4561 cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg caatcgtatg
     4621 tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg gggtcatcca
     4681 gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg acaagaaggt
     4741 gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt ggggctgctt
     4801 tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc tgcaatcgga
     4861 catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc ttttctattc
     4921 aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa tgctcgttcc
     4981 cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga tacggagata
     5041 ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt aaaaagtgct
     5101 ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc aatgattgcc
     5161 gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa cggagcatac
     5221 gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat aagagatgtc
     5281 cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg ctttacgaag
     5341 gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc agattcaaac
     5401 atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt agcgaaagaa
     5461 tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc agccgcaagc
     5521 ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa tcaatacatt
     5581 gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg aatgaaatta
     5641 tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga ttcaattgtt
     5701 cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc aaaagaagtc
     5761 catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat tgatattcaa
     5821 acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga atgtatcggt
     5881 gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg tctggaaaaa
     5941 gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc gacgccgtta
     6001 tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt cttttaaaag
     6061 cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag ctggcgtaga
     6121 tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa aaacggaacg
     6181 tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat cggtctttca
     6241 attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat tagcagtggc
     6301 aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt gtgtcaatga
     6361 tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa cggggaaaaa
     6421 tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg ttcaaggaaa
     6481 tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag gtaatgatta
     6541 tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga caggagaaac
     6601 gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt caaatgggta
     6661 ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat caaaactgcc
     6721 agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct atgtttcttc
     6781 cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca ctggtggagg
     6841 gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa tcaaacttgg
     6901 ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa ttcctgagat
     6961 ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc aagaatcgaa
     7021 agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg aaatcgggaa
     7081 agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat gagaatcgct
     7141 gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct atcgaaaaaa
     7201 ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata tgttttgaaa
     7261 cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt tgattcaaaa
     7321 aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga tttgatcgta
     7381 ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga taaaagaatc
     7441 atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat acgtgatgcc
     7501 tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca aggtgtagat
     7561 actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac gttcgattct
     7621 ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat tagtgaaatt
     7681 attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca gataaaactg
     7741 ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt tcaacaggag
     7801 gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa gaagtgacag
     7861 ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc catggtggtc
     7921 ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa aatatccaac
     7981 caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg aaaccagatg
     8041 tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg ctccgtagtg
     8101 cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat gaagaagtac
     8161 tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa ctagcggcaa
     8221 aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta acggattggg
     8281 tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa acgcttcgtt
     8341 acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg gaaaaatatt
     8401 cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat atccgagatg
     8461 cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc gccttgaaac
     8521 acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg gaagcagcgt
     8581 atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga gaagtagatc
     8641 tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc ccttcttata
     8701 cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg acagtagact
     8761 ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt ggacttcttg
     8821 tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg acaaaacgta
     8881 agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc aaacatgtga
     8941 aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga gccgggcaga
     9001 tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa atggaaggtg
     9061 cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat gcagccaaac
     9121 atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat tctattgata
     9181 tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt agacattaga
     9241 gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa catgcaataa
     9301 gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca ggaaatccgg
     9361 ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat tcagcgttaa
     9421 tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa gttcctttgt
     9481 taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt ccgacaaaag
     9541 cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat acttatcaaa
     9601 tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg tatatcaaag
     9661 aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa ggtgtagtcg
     9721 tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac cagcatcgat
     9781 ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa gaattctccc
     9841 ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa gatcataagc
     9901 gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat tcaccagtac
     9961 cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa ccagcggctt
    10021 tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt ttgattgcta
    10081 cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct gaaacgcaag
    10141 tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta ttagagaatc
    10201 gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg gttgcagctg
    10261 ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg gaagaagagc
    10321 tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga gcaggaggac
    10381 gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa aaaatttaca
    10441 ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt ggagaaaaag
    10501 ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa aaaatacaac
    10561 aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt ggtacacttt
    10621 tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg tacttctgat
    10681 cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga agatccagta
    10741 aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc agatatttat
    10801 ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc aatcaaacga
    10861 gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt tgatttttct
    10921 aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat ggattatgtg
    10981 gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt agctgaagcg
    11041 tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa tcaaaaacca
    11101 atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa tcagctgcaa
    11161 tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat gacagatgaa
    11221 gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga tatgacgatc
    11281 caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg gaacgaaaaa
    11341 ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac gacaccaact
    11401 ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat cgccggtacg
    11461 atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat gtctcgggaa
    11521 gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt gtcataagca
    11581 ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt cagcttcgag
    11641 atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt tcgtttatta
    11701 gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa tcccttgttt
    11761 tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa aagcaatatc
    11821 tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc tttgttctgt
    11881 cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga aatgagaggg
    11941 acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg taaaattttc
    12001 tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg aaggctgtga
    12061 gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa gcgagtcgtc
    12121 ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt gcgggatttt
    12181 cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac gatataatcg
    12241 tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag atacttcgtt
    12301 tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat caactggaag
    12361 tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg aactggcggt
    12421 ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc tttctgcgac
    12481 aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat ggaccaacgt
    12541 ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa ctattaaaaa
    12601 tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc taaataaaaa
    12661 cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt ggtttgctgc
    12721 taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag caagtttcaa
    12781 tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat tttttttcaa
    12841 ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta aagcagttac
    12901 tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca gataatcatc
    12961 tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac taataaatat
    13021 gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc cgtccatgaa
    13081 aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg aagacagtgc
    13141 catctcacca tctccagctt cgccgacata agtgattgga taataagaac caaggacagt
    13201 tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa aaactttata
    13261 catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg acagttgttc
    13321 cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa taaagaagga
    13381 gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg atccctttgg
    13441 ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg ttgtctataa
    13501 ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat cctttgtgac
    13561 ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag atcattttta
    13621 aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc atatggccgt
    13681 atcttatttt taagatgact agataatcat tgatatggct aatttctttt tcaagaggaa
    13741 tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca tgggtcatag
    13801 tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc aaactgttat
    13861 aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt gctaaatggt
    13921 attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt ttattcatgc
    13981 tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag ccaaggttcc
    14041 ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg acctttctct
    14101 ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact ccaagttcca
    14161 ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt gctaagtcga
    14221 tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca gaatctacct
    14281 gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta ttgatcagct
    14341 cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac gtactaattt
    14401 ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt tcttctagga
    14461 tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc cacatacttt
    14521 ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata tttgcgatcg
    14581 tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc aaagggataa
    14641 cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg cttaaatttt
    14701 ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat attctgctgg
    14761 gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt ttgaatattt
    14821 ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt acactcgact
    14881 acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc atcaatagtt
    14941 acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc taaagcaccg
    15001 tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc atttgtttct
    15061 aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac aattcggtga
    15121 acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt tggtttacga
    15181 ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt ctctgaacca
    15241 gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt gctgacaaat
    15301 aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac gaaaagctcg
    15361 ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc tcgctttgct
    15421 tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat catatccact
    15481 ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat gtagccattt
    15541 cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc agtatgcttt
    15601 ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg gtcaggtgct
    15661 tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag ggctaaaaaa
    15721 aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta tcttatcaga
    15781 taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa acttaaaaaa
    15841 atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa aaaatcaatg
    15901 ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga taaaaaatga
    15961 aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc attctattaa
    16021 gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga atcgctatgc
    16081 cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg gaattagaaa
    16141 aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat caagtagcac
    16201 aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct atcgatggtt
    16261 cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg atcgcctatg
    16321 atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat aattttggag
    16381 taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa ggaaaaggac
    16441 cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta atcaattaca
    16501 acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc gtgccatctg
    16561 gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg gcgcaagcaa
    16621 ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct gttttgtcgc
    16681 catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg tatgggagtg
    16741 aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc gttaaatcga
    16801 tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta gcaaaaaata
    16861 cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat gatactgaaa
    16921 cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta tctgtcgata
    16981 aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc gatctgaaaa
    17041 attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga taagaattat
    17101 ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa tccgagcgtt
    17161 agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg gagaaaacgg
    17221 agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg gctcctatga
    17281 cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag atagtgaaga
    17341 aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt caataaaaga
    17401 gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg aactgacaga
    17461 aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga atcttctagt
    17521 atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat tatcaaaatc
    17581 cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag aaagcgcgaa
    17641 tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca ttatttcaca
    17701 taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg atggacagac
    17761 gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg gaatggtggg
    17821 cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag tttattttaa
    17881 agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa acgaccacat
    17941 caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg gagcgggcag
    18001 aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat ccggacgtat
    18061 attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg caaacggact
    18121 cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg atattcggga
    18181 aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag ataaagaaaa
    18241 agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa actccatcca
    18301 tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat ccaagtggct
    18361 gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag atgttggggc
    18421 aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag ctgtctgtct
    18481 tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata cgatgaacga
    18541 aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct tgatgaaatt
    18601 aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg gataaaaaag
    18661 agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac agcatggtga
    18721 tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt ttctggcgtc
    18781 cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta gctgcaggga
    18841 tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg atggcgtttg
    18901 ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg atgacagtta
    18961 tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg gtagcttatg
    19021 cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt ggactgacac
    19081 aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa aaaatgtcta
    19141 cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca ttgattttag
    19201 gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat cgtcggaaaa
    19261 atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta tttacagcag
    19321 tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg attattttga
    19381 tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca gtagcaggtc
    19441 gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg atcaaaacaa
    19501 agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta gctggattag
    19561 ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg gaactggatg
    19621 caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga acaatcatgg
    19681 gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg attttaggcg
    19741 tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc gttgtgctag
    19801 acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca gaaaaaagac
    19861 tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca ttgtttcgtt
    19921 tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc tttttgctct
    19981 tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc ttgattaaat
    20041 taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat gaaagtattt
    20101 gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg ttctgaatgt
    20161 gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc tgccaacatg
    20221 cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta tttctatatc
    20281 atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa aaagcgtgga
    20341 ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat agagaagttg
    20401 gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg acatgctaac
    20461 tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt tgtgattgcc
    20521 ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc agatgcaaca
    20581 aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg ctttgggact
    20641 ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa gccgatcatc
    20701 gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt tggtgcgaca
    20761 atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga aacaaaagtc
    20821 gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca aaaaggcgaa
    20881 aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt gaaagataca
    20941 ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg aagagatctg
    21001 gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa tggagacaca
    21061 atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca ttaagtaata
    21121 agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt attatcgcag
    21181 atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt tttgtcacag
    21241 tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta aaatcaaaag
    21301 aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa aaacaaggac
    21361 cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga aggatcaatc
    21421 ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg aatcgttcca
    21481 ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc aaacgtggca
    21541 gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga atcgattggc
    21601 ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa ataagagaag
    21661 caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg ccagatgagc
    21721 ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg gaagaaaaag
    21781 aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat ttggaaagta
    21841 aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt cagcaagcaa
    21901 tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta gagtcacctt
    21961 ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt gggataccga
    22021 tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa aataaattga
    22081 aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg agtcaaaaac
    22141 gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt gaagacgatg
    22201 tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga acgattgatc
    22261 cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca acgaaaatcg
    22321 gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa gaaatgatgg
    22381 agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat gaagcaattg
    22441 atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg ataagcgctt
    22501 ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac tatgcctgga
    22561 ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta gatatgggtc
    22621 ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga atcaattaca
    22681 gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt ctagaaaagt
    22741 ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct tggatttaaa
    22801 tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact aagaaaaaac
    22861 cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa caaaactgta
    22921 taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa aatagaaaaa
    22981 atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat gctgttaata
    23041 tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt gtatttctca
    23101 taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt tattcactgt
    23161 ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg acaaatggca
    23221 aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc agatttccca
    23281 gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt acctgattta
    23341 tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt attagaccaa
    23401 cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac tgctggacaa
    23461 gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct tcttccaggt
    23521 tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc ttttttatgg
    23581 tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct accaccacaa
    23641 attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt gaagaaacga
    23701 aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca aggtgatttt
    23761 tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta tatccaaaac
    23821 aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac acttgcacaa
    23881 aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc gcttgcagta
    23941 tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc agtcctaatc
    24001 gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc aacccgctac
    24061 cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg cttccgtaaa
    24121 tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat cgaagcaact
    24181 aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca aaaggtttca
    24241 gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca aattgcaatt
    24301 tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa gcaatcacag
    24361 atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt gaagatgttg
    24421 ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc ggagaagacc
    24481 gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc ggtcttgcgt
    24541 tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc gaagcaatgg
    24601 acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact agaaatctac
    24661 ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg cattcggata
    24721 atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct tccaaccctt
    24781 atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt gttttcctag
    24841 aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct tacgaagttc
    24901 ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc acatacggag
    24961 caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat atatctgttg
    25021 aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt caatccgtgg
    25081 aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc gttgccgcgc
    25141 aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca atcggacgag
    25201 tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg ttgccaaatg
    25261 caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag aagggacgaa
    25321 acaaagtcat ggcttatcaa tttaaatt
//
LOCUS       DBBGSP010000044        24267 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000044 DBBGSP010000000
VERSION     DBBGSP010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.044"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(59..2404)
                     /locus_tag="ACIZE9_002066"
     CDS             complement(59..2404)
                     /locus_tag="ACIZE9_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HGC6093912.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            2683..3585
                     /locus_tag="ACIZE9_002067"
     CDS             2683..3585
                     /locus_tag="ACIZE9_002067"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HGC6093913.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            3798..5573
                     /locus_tag="ACIZE9_002068"
     CDS             3798..5573
                     /locus_tag="ACIZE9_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HGC6093914.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(5639..7225)
                     /locus_tag="ACIZE9_002069"
     CDS             complement(5639..7225)
                     /locus_tag="ACIZE9_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HGC6093915.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQEMVEEIE"
     gene            7476..7700
                     /locus_tag="ACIZE9_002070"
     CDS             7476..7700
                     /locus_tag="ACIZE9_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGC6093916.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            7841..9592
                     /locus_tag="ACIZE9_002071"
     CDS             7841..9592
                     /locus_tag="ACIZE9_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HGC6093917.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIISAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            9592..11376
                     /locus_tag="ACIZE9_002072"
     CDS             9592..11376
                     /locus_tag="ACIZE9_002072"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6093918.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            11702..12553
                     /gene="licT"
                     /locus_tag="ACIZE9_002073"
     CDS             11702..12553
                     /gene="licT"
                     /locus_tag="ACIZE9_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGC6093919.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVVQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            12650..14530
                     /locus_tag="ACIZE9_002074"
     CDS             12650..14530
                     /locus_tag="ACIZE9_002074"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGC6093920.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEVEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVPFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTETAIYGITLPKK
                     KPFIYSMIGGAVSGIYLMASGTISYTMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDDIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(14570..15472)
                     /locus_tag="ACIZE9_002075"
     CDS             complement(14570..15472)
                     /locus_tag="ACIZE9_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC6093921.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDDWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNDVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            15703..17106
                     /locus_tag="ACIZE9_002076"
     CDS             15703..17106
                     /locus_tag="ACIZE9_002076"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGC6093922.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALNDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            17106..18539
                     /locus_tag="ACIZE9_002077"
     CDS             17106..18539
                     /locus_tag="ACIZE9_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGC6093923.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQVKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            18684..19610
                     /gene="trxB"
                     /locus_tag="ACIZE9_002078"
     CDS             18684..19610
                     /gene="trxB"
                     /locus_tag="ACIZE9_002078"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGC6093924.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            19824..21551
                     /locus_tag="ACIZE9_002079"
     CDS             19824..21551
                     /locus_tag="ACIZE9_002079"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGC6093925.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEEAKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            21566..21916
                     /locus_tag="ACIZE9_002080"
     CDS             21566..21916
                     /locus_tag="ACIZE9_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HGC6093926.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(22008..22868)
                     /locus_tag="ACIZE9_002081"
     CDS             complement(22008..22868)
                     /locus_tag="ACIZE9_002081"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HGC6093927.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLKQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            22960..23388
                     /locus_tag="ACIZE9_002082"
     CDS             22960..23388
                     /locus_tag="ACIZE9_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HGC6093928.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            23550..23726
                     /gene="rpsU"
                     /locus_tag="ACIZE9_002083"
     CDS             23550..23726
                     /gene="rpsU"
                     /locus_tag="ACIZE9_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGC6093929.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            23753..24199
                     /locus_tag="ACIZE9_002084"
     CDS             23753..24199
                     /locus_tag="ACIZE9_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HGC6093930.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         7691 a         4297 c         5199 g         7080 t
ORIGIN      
        1 ataagggact gtgacaatac tattgtcaca atctcttatt actgtgtatt ctattaaatc
       61 aatcatcttt ctcatctgat tctttggttg cttgattcgc tcttgcataa gctgaagcgg
      121 tgttccagta atctgtatag ttttcatcgg taccgccaac gccaaattta aaggcgcttt
      181 tcttcggtcc atttttcgcc catagcgatt caactgtttt tccaggtgtt tggatggatt
      241 ttttattgac agtaactttt ccaggtgttt gaccagtaaa tccagatact tttttcttca
      301 tcacatcaga tgataattcg aatttctcat cagtgccaaa aatgtcaggt tttgcttggt
      361 aagcttgatt gatcagattg gcaagataat tagccgaacg tatccttgct ttgctgtcca
      421 ttccagtatt gtcatcgtgc cctgcccagc tactgatggt aatagacgga gtagagacaa
      481 ttagccatga atctcggtat tcattggtag aaccagtttt tccgacccaa tctgcttttc
      541 ctagatttcc gtttaagctt gagatggcat ctttgaatgg tgtagtgatt tttgcattga
      601 tcacactgcg catcatgtca ttcatgatcg atgccgttgc ttccgaatag atccggacag
      661 agttgctttc gtgtttataa attacatttc ctgcgttatc tgtgatggaa tcgatgatat
      721 agccttcttc atagacgccg ccgtttgcta aagcctgaaa tccattggtc tgttgaagcg
      781 tcgtgacatc tactgtacct aaaggagcag attcaacgcc ccaattgtca tttgccgggt
      841 agttcatctt tgccaagtag tgctcgtaag catattgttt cgatccaccg gaattcaaca
      901 catcttgata taagtgataa gccgggatat tgttggacca ttctagtgac tcacggacgg
      961 tttggaaggt gttcgatcct tcgttagtag cattgacgat tttctcgcca gcattttctc
     1021 cttcttgcca agttgttgca taatctgata cacgggattc tgatccgata agccccatgt
     1081 cgattgcagg tccataaaca agaactggtt tgattgatga gccagcttga cgttctgtat
     1141 cgaaggcatg gttattttga ttctgactgt aattccgtcc gccaacgaat ccgtagatgc
     1201 ggccagttct gttatccatc aatacatttc cggtttctac ttgactgcca gcaccatcat
     1261 ctaacatgta tccataattt tctacgccat tttgcaatgc agcatagaca tctttatcga
     1321 ttgtcgaatg gattgtatat cctttatttt ggattgtttg ctgtgccttt tgataataag
     1381 cgtcactgac cgatgaatca gacatatcag cgttgtcttt ttcagccaat tgttgtgcaa
     1441 tgattcttgt tgcttcattc atcacagtat aatacaagaa ttctctgtca gtctgttctg
     1501 cgatttgttg tggtagaaag tcttttgtaa ggtcataggc ttttgcttct tcgtattgtt
     1561 ctttcgtaat ttggccttca cgatacatac tgaataaaac aaaatctttt ctggcaaggc
     1621 cggcagaaag atcttctttt agcgcacctg tgttcgtgta tggactatac gtgatcgggc
     1681 tttggggtaa tccagcgata taagcagctt gcggcagcgt cacatctttt gcatctacac
     1741 caaagattcc tcttgcagct tcctggactc cagcaatgtt ttgtccctta ttattacgac
     1801 caaatggtga gacattcaaa tacgtagcaa tgatctcatc ttttgaaaag tatttttcta
     1861 cttgtgcaga aagaatgatc tcgtttgctt tacgtttgaa tgttgtttca tctgtaagga
     1921 tctgctgttt gactaattgc tgtgtcaaag ttgatccacc agaagagcca ataccagtag
     1981 cttcagatac taacgctcgt aaaacagctt taggaacgta accttggtgt ttatcgaagt
     2041 attcatcctc tgtgctgata attgcagttt tcaataaagg tgaaatttta tcagatgaaa
     2101 tagtcgtgcg catcagatct gtctggattt ttgatatctc tgtattatct gcataaacaa
     2161 tctttgacgt ttctgtaatg tttcctagtt ctgtctgcag tgctttttta gtcggcaatt
     2221 gtgtgtcttc gacgagatag gcaaaatagc cagcgcctat tccaatacct agagctgcga
     2281 acatcaaaag aagaacagta ataaaaacag tcaatgattg aaaaactcta aaaataatct
     2341 taggaacaaa ccatttttct ttttttcttc tattctgttt ttttcgagta tttttgcgtg
     2401 gcaaaagggt cacctcaact aatggtttta tttcgctaat tatagcaaat aatagaacaa
     2461 aaaaacagac aaggctgttt ttggcaggaa tttctttttt aaaggagtta aaacgtgaga
     2521 aaatgatctt ttttataaaa gagttcttaa gcttttcttt agagaaaatt tcagttacta
     2581 tggagaacag ggcaaagaaa aatcaatcat tttctttgta tatcatctta ccaatatata
     2641 ggaattgtta gtaacaattg cctttcaagg aggaatccat ccatgttatt aggctcacac
     2701 gtcagcatga gcggaaagaa aatgctgtta ggagcagcag aagaagcagc cagttatgga
     2761 tcttcgactt ttatgatcta tacaggcgcc cctcaaaaca ctagaagaaa agccatcgaa
     2821 gagatgaata ttgatgccgg aaaagcgtac atggcagaaa acggtctaac aaatatcgtc
     2881 gttcatgccc cttatatcat taatttgggg aatacgatca aaccagaaat gtttcctttt
     2941 gccgtccaat ttctgagaga agagattgtt cgtgcggaag ctttaggcgc tactcaaatt
     3001 acacttcacc caggtgctca tgtaggggca ggaacagaag ccggaattgc tagaattatt
     3061 gaaggcttga atgaagtttt gacaaaagaa cagacggcac aaatcgcttt ggagacaatg
     3121 gcaggtaaag gtacggaaat cggtcgaaca tttgaggaat tagcgcaaat catcgatgga
     3181 gtaaaattga atgaaaaatt atccgttact tttgacacct gtcatacgaa tgatgccggt
     3241 tataatatta aagaagactt ttcaggtgta atggaagagt ttgataagat catcgggtta
     3301 gatcggctta aagtactcca tatcaatgat tctaaaaatc cgcaaggttc gcataaagac
     3361 cgacacgcca atattggttt tggaacaatc ggattcgaca cgctgaataa gatcgtccat
     3421 gatccaatgt ttgacaatat ttcgaaaatc ttggaaactc cctatgtcgg caaagataaa
     3481 aagaaagctt acgcaccata tggaaaagaa atcgccatgt tcaaagcaca aatattcgat
     3541 ccagaagtgt ttcctgagtt attagcagaa gaagtgatac tctaagattt tctatctgac
     3601 agcagcaaaa aaggaccagg cacattgcct tgtccttttt tgtttaagaa acaaaggagt
     3661 gctttttgca gtctttttca tcatgcatct tctcccccct ctttttaaat ttagacaaac
     3721 agggtatact ggtagaaaag taaaaaaacg aaaagtttca caagcaagtg gcaaaacgtg
     3781 attggaagga cgaaaagatg ctgaacactt taaaaccctt gatcaaccaa ctaaaaaaga
     3841 aacatacata ctttattctt ggcatagccc tattatttac aattattcgt ttgtatttat
     3901 atagtaaagc aatctatgga acagacatgt cggcaaccta tgatgaccag ctgctgattc
     3961 gctatgctca aaatattttg gacggtaaat ggctagggga gtatacgact acaacacttt
     4021 ccaaaggaat ctcctacagc ttatttttag tacttgcaca taaactgcat ctttcttatg
     4081 cagttttgtt cggcatgttc agtatttttg ccagtatatt ggttgcactc gcgtttaaac
     4141 cgatcgtgaa gaacaagtat cttcttttaa gtttctattt ttattttttg ttttctccga
     4201 ttagttttac acatgaatat tccactcgaa cgtatcgtaa tgccctcgtg attccggctg
     4261 ttgagatcat tatcgcttgt ttactagcta tttattaccg caaatacggt tctagcagaa
     4321 aattgctgcc atggttttta gggctttctg tcgcttttcc tttcttttgg ttcattcgcg
     4381 aagattctat ctggcttctt ccttttactg tagtagcttt gggtatcagt ttcgtccaga
     4441 tcttgctagg gcaagacttt tctttcaaag aagtaaagaa gttaaaaaaa cgactctttc
     4501 ttctctcgaa acgggaatgg ctgaaacttt cattgttttt acttcctata gttggctttt
     4561 ccatcgtcta tcagtggatc gaatataaaa atgagacaac atacggtatt gcaaccatca
     4621 atgaccgttc cagtggagaa tttggacgtt tgatgaaaca actgatccga atagatgatg
     4681 aaacgaactt gaataaagaa aacagtgaga tatgggtctc acatgctgca ctaaataaag
     4741 cattagccgc atctcctaca ttccatactg tttctacccg tattgacgaa ttatatacga
     4801 ctcacgcgtg gactcaaggt ggaaaagtaa aagaattacc cggagatatc atcttttggg
     4861 cattgcgaga tgtggtaagc gaatctggtt attaccaaaa caatgcaaaa gaaaccaatg
     4921 atttttggaa aaaagtcaac caagaattag aagaagccta tcacaaggga accatcaaaa
     4981 agaaaaaaga gttctatctg atgggatcag gagatggaaa gacgatgagt gatctaccaa
     5041 tcgtattcga tttccttcaa tcaggatacg cttatgcatg gcgatataaa gatttccatc
     5101 aaggaggaaa ttatagtttc ggaacgcaag aacaagtcaa acaggctcaa gaattattaa
     5161 accttccgct aatggagaat tggatcgata gtaatgaacc gagaacacct aatttccaat
     5221 taacaaaatc agcaaaagtc gcgaatgtca tcataaaaat ttaccaagtt ctggctattc
     5281 ccgtgctgat tgcttcaata gcagggatat tacttatgat actaggaacc gtatttgcaa
     5341 aagctgatcg tgcctattat agttcctctt tgattgtggt caccggatta atactgacac
     5401 aattggtttt tcttttcggt gtctcgtggt tttgttctta tgcgccagaa aaaaaggatt
     5461 attttttaag tgtctacact ggcgcaggcg tgccgttaac gcaattcatc gtagtaacaa
     5521 gcatgctagt tttcagtaaa ttaaatctga aaaaagcttt atcttctaaa taaaaagacc
     5581 cttggtagct agatttttaa cctaactatc aagggtcttt gtgtggaaaa atcagttttt
     5641 attcgatttc ttctaccatt tcctgcaaac gctgttcata ttttttgttt cctttatata
     5701 aatcaccaat cgtccatgcc aacaggagga ggacaagaac aatgattaca taagcgatgt
     5761 gatcagccaa tgctagttga gcggaagtgg cttgctcgcc gaagaaactt tcgatctgtc
     5821 ctggtaatcc tcgtaagttc aagtaagtta gactaatcac agagaaccag ccaagaagtt
     5881 ttacgatgaa tgaattttta aatcggctac ccatctccgc ttggctgttg gtcatcatca
     5941 gtaaagggat catcgaaaac ggcaacgcaa aagccaagaa cacctgggat tcattcatta
     6001 agttattcaa agcggtatgt tcttcgatcg ttccttttgt acttgtaaac aaaacacaaa
     6061 tcaatacagg aatcacagaa agcaatcgtg tgaccagtct tcttagccaa atcgggatac
     6121 gcatatggat gaatccttcc atgatgactt gaccggtcaa cgtaccagta atagtagagt
     6181 tctggccaga agcaagaagt gctacagcaa ataaagtgga caagatacca gattttgcta
     6241 cagcaatcaa gataccattg ctcatagctg atggatcaga taaagcttca tacagaccaa
     6301 aaaaggaagg atcttgaaca gaaccggttt tgaagacagc gacacccata atcaatagca
     6361 gcgcattgac tagaaaagcc atcgacaatt ggatattaga gtcccaagta gaaaaacgta
     6421 cagcttgtgc tacatcttct tcgtcttggt gatcgatctt ccgagtttgt gaaactgctg
     6481 aatgtagata taagttatgt ggcatgactg ttgcgccaat aatccctaat gctccagtta
     6541 gcggagtttc gccaccaatg acaggtgagt cggagaatgt atggctgtta gggataaagc
     6601 cagcaaataa actgtgccaa tctgggttag acaagccaac ttgatagaca aaaacgaata
     6661 aaatgacgaa aatcaagcag acaaccagtg cttcgatctt acgaaacccg acttttgtca
     6721 gtagtaagag aacgaaaaca tctaatacag taataaagac ggcaatcacc aatggaatat
     6781 caaaaagtaa gtagagggcg attgctgcac caatgacttc tgcaatatct gttgccataa
     6841 tggctaattc agtcaagatc cataaaatga cacccaatgt cttacttgtg cgtgctcgga
     6901 ttgcttgggc caaatccatt tgggtcacga ttcctaattt tgctgccata tactgtaaaa
     6961 gcatagcaat cagactagac atcaaaataa ctgacatcaa taaatattgg aaattttgtc
     7021 ctccggtgat cgaagtagac cagttacccg ggtccatata cccaactgct actaacgcac
     7081 caggtccaga gtaagcaaga agtgttttaa aaaaactttt cccctttggt acatccactg
     7141 ttccatttac ttcagctaaa gataaaccat ttgtatgttc aataagtcga tgcttatgaa
     7201 attgtttgtt ggattgatta ttcaagaaaa aaccaccttt cctatttatc tacgattaca
     7261 ttctacacct caaaaagaaa aaattaaaga aaaagattcg gtatgcctaa ttttttttcg
     7321 tggcgtgtct tgctagatga cgaaagaaat tttgttctcc tctaaaaaaa ccactatttt
     7381 ttgcatgaaa ctaaagaata cgcctttctt ttttcaataa actttagtaa aataagtcat
     7441 tgagagcaat tcggaaatag aaaggagaga tttatatgtt atcaacaggt attgtcgtac
     7501 ttattgctat tattgctttg ctaatcggcg cagtaggtgg ctttttccta gcgcgtaaat
     7561 atatgaaaga ctatttagaa aaaaatcctc ccgttaatga ggacatgttg cgatcaatga
     7621 tgatgtcaat ggggcaaaaa ccatctgaga agaaaattcg ccagatgatg cagcaaatga
     7681 agaaccaagg gaaaaaatag gttctgaccc aacgactttt tacgggctga ttttttcagt
     7741 ccgtttttta tttcgtaatt tgttagacta ttcagattat tcagcaaaaa gacaagcaca
     7801 gacaatccta ggctcttgat aaagacaaag gaggagtaaa atgtcgattt ttagaaagtt
     7861 aggctggttt tttcgtcagg aaaagaaaca ttatttaatt ggggttttct cgctattcgc
     7921 agtggccttg gtacagttag ttcctccaaa agtgattggg atcatcattg atgagattgc
     7981 cgataaaaat ttatcagtaa agatcatttt cgggtggatc ttcctattga ttatcgctgc
     8041 ttttttacaa tatctttttc gttatatctg gcggacgaat atttggggaa gtgcagctcg
     8101 gttggagaaa gaacttcggc agcagttatt caaacatttt acagaaatgg acaatctctt
     8161 ttaccaaaaa tatcggactg gggatttgat ggctcatgca acgaatgatt tgaatgcgat
     8221 ccagaatgta gcaggagctg gtatcttgac ctttgcagat tcagtgatta cgggcggaac
     8281 aacgatcatt gcgatgattt tgtttattga ttggcgctta acactgattg cgctgattcc
     8341 tctgcctttg ctggccgtca cttcacgagt gctggggtcg aaactccatg atgcttttcg
     8401 tgattcgcaa gaagcttttt ctagtatcaa tgataagaca caagaaagta tcactgggat
     8461 caaagtcatt aaaacatttg gacaagaaaa agaagatcta gcggattttg aagaaaagat
     8521 tgaagatgca attattaaaa acaaacgagt caatttttta gactccttat ttgatccatt
     8581 cattaccttg attatcggtc tgtcttatgt tgcaacaatt attttaggtg gaaagtatgt
     8641 cttggaaggc acgatctcga tcgggcagat ggtctcattt attagttata tcggtatgct
     8701 tgtttggccg atgtttgcga ttggtcgatt gttcaacgta ttggaaagag gaaatgcttc
     8761 ttatgatcgc gtcaatgaac ttttgcatga aaaaacgcat atcgtggaac aactgggtgc
     8821 agtgcagacc ccggcaaaag gcgagctgaa tgtagctatt tcctctttta attatccgaa
     8881 agaagaatca ccagcattag aacaaatcaa gtttgcaatc caagaaggag aaacattagg
     8941 tattgttggg aaaactggtg cgggaaaaac gacgatcatc aaattactga tgcgtgaata
     9001 cgatgattat caagggaaaa tccaatttgg cggacgttcg atcaaagaat attcattgaa
     9061 tgctttatta ggatcaatcg gctatgtgcc tcaggatcac ttcttgtttt cgatgaccat
     9121 tcgagataat atccgttttt ctaatccaaa actttcagaa gaagaagtag agcatgcggc
     9181 ttctttagca tttatcaaca atgaaatcaa ggaattacca aaaggttatg ataccttagt
     9241 tggagaacgt ggagtctctt tatctggcgg acagaaacaa aggatttcga ttgctcgagc
     9301 attgatcaaa aatcctgaat tattaatatt agatgatgca ctttctgcag tagatgccaa
     9361 aacagaagaa gctatcttgc ataatttaaa agaaataaga aaagagaaaa caactatcat
     9421 ttcagctcac cgtttaagta gcgtgatgca tgcaaaagaa atcattgttg tcgatcaagg
     9481 gaaaatcatt gaacgaggaa cccatcatga gctgcttgca ctaggcggct ggtatgaaca
     9541 aatgtgggag aaacagcaat tagaagcgaa gatagaagga ggcgaggcct gatggatgaa
     9601 aattatcaat cggaatggac aaaatcgatt ccacttaaag aacagaaaaa gatcatcaaa
     9661 cgactgatga agttcgccaa accttttaga agaacgttca tcgttgctat cttatttgcg
     9721 tttgctctgt ctgtgatcaa tgtcctattg ccaaggatca tccaaacttt tatggatgat
     9781 catctggcta aacagtcggc tacgacacaa gttattttgt tttttgctgg tatgtactta
     9841 tttggagtca tagtaaaaag tatcatttgg tttttccaat ggtatttgta ttccatggct
     9901 tcattgaaga cctatcagta tattagggta aaattatttg aaaagctgca tacactaggt
     9961 atgcgttatt ttgatcagac accggcagga tcaaccgttt ctcgagtgac gaatgacaca
    10021 gaaacgctat ttgaattttg gtacgtcttt ttgatggtat tgactgggat ctttgcagtc
    10081 gtttcttcat tcattgccat gtttcaaatc aatggagaaa ttgccttgtg gactttggtg
    10141 ttcttgccaa ttttaggaat agtcatctgg tattaccaga aatttagttc tcgtatttac
    10201 cggaatatgc gggaaaaatt aagtcagctg aatacgaaat tgaatgaatc gatttccggc
    10261 atgcgtatta tccagcagtt tcgccaagaa gctcgtttag ctaaagaatt tgaacaagtg
    10321 aacaatgagt atttagacac gcgttatgcg atgatcaaaa caaattcgat tctgttaagt
    10381 ccgatcatca attttctata tgcattggcg attgcgttgg tgttgacttt gtttgggatc
    10441 gatgcgttgc attctcccgt agaagttgga ctgatctatg catttacgac ctatgtccag
    10501 ggatttttta atccaatgtc tcaaatgatg gactttttga gcatcttcac agatgggatg
    10561 gttgctggta gtcgtatctt gaagattatg gatacagaag aatatgcacc acaacaaaac
    10621 cctggagcag atcaaatgat tacttcaggt aagattgagt ttcgcaatgt aagcttttct
    10681 tatgatggag agcacaatgt attaaacaat atctcttttg ttgctaatcc gggagagacc
    10741 gttgcattag tgggacacac cggaagtggg aaaagctcga tcatcaatgt gttgatgcgg
    10801 ttttacgaat tttatgaagg tcagatattg attgatgatc atgacattcg agaatatcca
    10861 atggaagagt tacgtaagaa aatggggctg gtcttgcaag atgctttctt gttttatggg
    10921 gatatcgcag gaaatattcg gatgatgaat ccagctatca cagacgaaca gatacgccat
    10981 gcggctgagt ttgttcaagc aaacaaattc atcgatgaat taccaaaagg atatcactca
    11041 aaagtgatcg aacatggtgc cagctattct agtggacaac gacagctgat cacttttgcg
    11101 cgaacaatcg tgactgatcc taaaattcta gtattggatg aagcaacagc aaatatcgat
    11161 actgaaacag aaggattgat ccaagaagga ttggcgaaaa tgcgacaagg acggacaacg
    11221 attgcgattg cccatcggct gtcaacgatt cgagatgcag aattgatttt agttttagac
    11281 aaaggtcata tagtagaacg cgggaatcat gaaacacttc tagcgcaaaa tggtttgtat
    11341 gcagatatgt acaaactgca aagcagtggt atataaaaga tgttgtgaca gtagcatttt
    11401 gacctaagca ctagagtgaa aataaaacat agcttcccat atttttcatc tgtgagagtt
    11461 agtgtcgtag ttaccagatt taaaaaagac gacgtcagct agtcagaagt gcctaatagc
    11521 ccctaagaaa gcgttgacaa aatcgtttgc tttcgataat ataaagaaaa cgatacaact
    11581 tggatagtga ttgcctgatg caagctaaac ctaatgagtc tcccatggtt tcatggacgg
    11641 ctttttgggt ttttcttttt gttttggata cagccctata tatcatggaa aggagcaaaa
    11701 catgctgatt gagaaagtac tgaataacaa cgtcgtaata acaagggatg aaagagatcg
    11761 ggaaatgatt gtgatgggaa aaggattggc attcaaaaag aaggtgggtg acccgattct
    11821 tgattcatgc atcgacaaaa aatttcagtt gacaaatgac ggactttcac aacagttcca
    11881 agaattggca caagcgattc ctcttgagta cttagaaatt tcttgtgaaa tcattgaata
    11941 tacaaaagag gctctgcaag tccatttaaa tgattctgtg tatatttcat tgacggatca
    12001 cttgtataca gctatcgaac gtcaaaaaat ggggatcttt gtgccaaatg tattgctgta
    12061 tgatatcaaa caactgtttc ctaaagagta tgccattggg aaaaaaacag tgaagaaaat
    12121 ctcggataaa taccacatca agttatcaga agacgaagcc ggatttatcg cattgcattt
    12181 agtcaatgca caaggcattc aaagccagca agacaatacc tacctgttta ccacaacaat
    12241 acaggatatt ttaaatatcg tccgctatta ctataagatt acatttgatg aagattcagt
    12301 ccactttttt cgattcgtca cacacctgcg tttttttctg acacgtgttc tagatggagc
    12361 gaaatcagaa gatggagaag tttctgagga attgttccaa gttgttcaaa aaaaatataa
    12421 ggatacgttt ggttgcgttg agaaaatagc agacttttta accggggctt tcgactacca
    12481 gatgtccacg gatgaaaaaa tgtatttaac gatccatact gcgcgtttag tgcatgagaa
    12541 tcgttgtaaa taaataaaaa aggaggacaa attaacaaga acgtatgaaa ataagggtag
    12601 tgacattcag ttggctaaac cttccactaa ttaattggag ggaatagaaa tgggaaaata
    12661 ccaggaatta gcagaaaaca tcgtaaagaa tatcggagga aaagaaaata tccgtagctt
    12721 gacacactgt gtgacgcgac ttcgtttcaa actaaaggag gaaaataaag caaaggatga
    12781 tgttttgaaa aagatggaag ggatagtcac catcatgaaa agcggcgggc aatatcaagt
    12841 tgtaatcggg aatcatgtgc cagatgtcta tgcagaagta ctgacagtag ccgggatttc
    12901 cgatgaagta gaagaagagg tttcttcaag tagtaatctg ttcaatcgat taatcgacat
    12961 attaagtggc tgtttccagc cttttttagg tgctttagct gcagcgggaa tggtcaaagg
    13021 attaaatgct ttgttcttgt ttctcaaatt ttatactgaa ggatcgggta cgtacatcat
    13081 gctgaatggg ataggggatg caatttttta tttcatgcca gtgatcttag ggtacacagc
    13141 agcgaaaaaa tttcatctga atccgatggt ggggctcgtg attggtgcag cactttgtta
    13201 tccgactgta caaggagcag cactacaaag tggtttccct gatggcagtc ctgcgcctta
    13261 tagcttgctg gggcttccgg cttatgaaac atttttgggt atcccatggg tgggcagcag
    13321 ttataccagt agcgtcgtac ctgttatctt cattatcgca tttgccggac aagtccaaaa
    13381 aattgccaag aaatggattc ctgcagtcgt ccagaccttt ttggttcctt tttctgtgtt
    13441 attaatcgca cttcctgctg gttttttgat tatcggtccg attgtcagta tactgacaga
    13501 tctattaagc acgggattcc aagcattgat ggacttttct ccagctgtgt atggtgcagt
    13561 tctagggttt ctttggcaag tactggtgat tttcggactt cattggagta ttatccctct
    13621 tgcgattatg cagctagcgc aaaatgggtg gagtcagatg ttagtaggcg tttatggcgc
    13681 gagttttgca cagacagcag tggtattggc gatgtatttc aagttcaagg atcaaaaaat
    13741 gaaggcgctt tgcatgccag ctgtgatttc aggaatcttc ggcgtaacag aaacggctat
    13801 ttatggaatc accttaccaa agaagaagcc atttatttac tcgatgattg gtggtgctgt
    13861 ttcaggaatc tatttgatgg catctggaac aatcagctac acaatgggcg ggttagggat
    13921 ttttggggtg gtaaactaca tcacggaaac agacgccagt ggtatgtttc aagcgtttat
    13981 cggcattgct attgcttcgg taatcgggtt ttcgctgact tttttctttt ggaaggatga
    14041 agcaggtgaa acagatgata tacagaaaaa atcaggtaaa gaaattgtaa aaacaccgat
    14101 acaaggacaa atcgctccac taaatgcagc aaaggatgca gcttttgcac aaggaacact
    14161 aggtcgagga atcttgatct accctgaaaa aggagaagta cgtgcccctt ttgacggaac
    14221 agtcatgacc ctgttcccga cgaaacatgc aattggaatg gtttctgaaa cagggctgga
    14281 attgctgatt catgtcggat tggatactgt gcagttggaa gggaaatatt ttgaaagctt
    14341 agtgcagcaa ggagaaagag tgaaacaagg cgatctgttg ctacgcttcg acaaaaagaa
    14401 aatcgaaaag gaaggataca gtttagaaac acctgtgatc gtcaccaatt acacggatta
    14461 tttggatatt ttggaaaacc aaggggagac ggtcgggcca gacgatgcac ttatcaccgc
    14521 actgacctga acggttaggt gaagaatgga ctaggcttaa ctattctttt tattccactt
    14581 ctttattttc aaaattgaaa ggctctttca tgatggctga gctgataggg cgtttatcga
    14641 atttttgacc gacagaaatt agatggacta aattctgttg ataattttct gcaaaaacac
    14701 aactatataa cacgtctaga agataacaaa ttgatgtatt gatcgtaaaa ttaccaattt
    14761 ttgaatacag tcgctcgcgt gtcgtaagtc gcaaagcggc tgtactcatt gcagatagcg
    14821 ttgaatcacc gatactggtc aaagctaaaa ttggaacatc attttgtttc aatatttctg
    14881 cggtacgaag gatcacattg ttttcacccg tataagaaat cagaatcccg cacatatcac
    14941 tcgtgcaatt gtacgcttca tagaacgatt caccaaaagt ggtgacaatc gtgacatcca
    15001 ttttgatgcg cttcattttc agcatgaaat cttgagaaat caaagtattc gagttactgg
    15061 cgaaaatcac gatttttttt gcttgaagca ttagttgttt ggctttttgc agttggtcat
    15121 gatgaatgag agaaagtgta tcatgaatcg tcatctgttc taaagaagcc attttatttg
    15181 cgatcgtcat aataccgtct gtggtggaaa aaggaagatt cgcatctacg tcttgaaaat
    15241 tcccttcaag ataggctgtt tcagctaaaa aagcattacg aaaactgacc cagtcatcaa
    15301 aacccatttt ttttgctaca cggatgagtg tagacgggtg gacatagcat cgctcagcga
    15361 tctcttggat ggtcatttcg ccaagtgctg gagaatcgct taagagaaac tggatcactt
    15421 cattttctga aggagaaaag gagatttctt tgattttttc acgtaataac atgtagttac
    15481 cttcttctta tttttttacg taaattataa cttttttgaa aatgttttgt aaacggattt
    15541 atactatata acttaaaata gacttttttt gacaagatat ttacaaaaat ccactagaaa
    15601 acagtaactt ttgtaaatgt tactggaaag aaacggattt ctattgtttg ttttgtttac
    15661 aaaaaagata atgaaagtgt aaaaaagtaa aggagtgaga acatggcaaa aggaatcaaa
    15721 atcgctacga ttggtggagg cagcagttac acccctgagt tgatggaagg atttatcaaa
    15781 agatatgagg aattaccgat acgagaaatc tggctcgtag atgtagaaga aggaaaagaa
    15841 aagcttgaga tcgttagtca gatgtctcag cgtatgtggg atgcttctcc gtatgaagtc
    15901 aaaatctatg caactctgga tcgggaagaa gcattgaatg atgcggattt tgttacgact
    15961 cagtttcgtg tcggtcaatt agatgcacga atcaaagacg agcggatccc tagttattat
    16021 gggatgattg ggcaagaaac aaatggtgct ggcgggatat tcaaagcttt tcgtaccgtt
    16081 ccagtggtct tggcaatcgt tgaagacatg aagcgtttat gtccaaatgc ttggctgatc
    16141 aatttcgcga acccaagtgg gatggtgaca gaagcagtta tcagatatgg caaatgggat
    16201 aaagtgattg gattatgcaa tgtgccagta atggcgatga tgacagaacc agcaatgctt
    16261 ggcaagaaaa aagaagagct gatctacaag tttgccggtc taaatcattt ccattggcac
    16321 aaagtagcag ataataaagg aaatgaccgc acggcagaat tgattgatcg tttatacgat
    16381 gaagacaatg gattgccgaa aaatatcttt gatatcccgt ttttcaaaga acaattaaaa
    16441 caaatgaata tgatcccttg tggctaccac cgctattact accgtgaaga agaaatgctg
    16501 gaacatgctt tagaagaata tcaaacgatt ggtacaagag cgcagcaagt gaaagaaaca
    16561 gaagcagagc tatttgaatt atacaaagat ccagaattag accataaacc tgaacaattg
    16621 caaaaacgag gtggcgctta ttattcagac gctgcctgtg aaacgattgc ttcaatctat
    16681 ggaaataaag aaacacagat cgtggtatct acaaagaatg atggagctgt tcctgacctg
    16741 ccggcagatt gtgtagtaga agtcactgcc tatgttggcg cacaaggagc gagaaatgta
    16801 gcgtttggtt ctcttcctgc tgctgaaaga ggctggttgc aagtaatgaa gaatatggaa
    16861 ttgctgacga tcgaagcagc tgtgactggt gattatggga cagctttaca ggcgtttacg
    16921 atcaatccgc ttatacgatc aggaaagaca gcaaaacgga tcatggatga gttgtttatt
    16981 gcacaccagc agtatttacc gcaattcaag gaaacaatca gccgattaaa agaagaagga
    17041 atcgaagttc aagatgaact ggcaagagaa ttatcaggta atacacatat aatggaggaa
    17101 gtataatggg attcagaaaa gattttttat ggggcggtgc tacagcagcc aatcaatgtg
    17161 agggcggtta tgatgaaggt ggacgcggac tagcaaacgt agatgttgtg ccaatcggaa
    17221 aagaccgttt tcctgttatc accggaaaga aaaaaatgtt tgaatttgat gaggatcatt
    17281 tttatccagc aaaaattgca atcgatatgt atcatcgtta taaagaagat attgctttgt
    17341 ttgcagaaat ggggttcaag acttatcgaa tgtccatcgc ctggagtcgt atttttccaa
    17401 tgggggatga aaaagagccg aatgaagctg gcttgaaatt ttatgaggat gtctttaaag
    17461 aatgccaaaa gcacggaatc gagccacttg tgacgattac gcattttgat tgtccaatgc
    17521 atttgatcaa agaatacggt gcgtggcgtt ccagagaact cgttggtttt tatgaaaatc
    17581 tgtgtcgagt catcttcaat cgatataaag gacttgtcaa atactggctg acattcaatg
    17641 agatcaatat gatccttcat gcaccattca tgggagcagg actgtacttt gaagaaggag
    17701 aaaacgaaga acaagtcaaa tatcaagcgg cacatcatga gttggttgca agtgccatcg
    17761 caacgaagat tgctcatgaa gtagatccgg agaacaaagt aggctgtatg ctggcagcag
    17821 gagcatatta tccatacact tgcaatcctg aagatgtttg ggcttctaga aaatcagatc
    17881 gagaaaatta tttcttcatt gatgttcagt cacgaggaga atacccagct tatgcattga
    17941 aagaaatgga acgaaatggc attcagatcg aaatggaacc aggggatgcc gcattgctga
    18001 aagaacatac tgttgatttt atctcttttt cttattattc ttcccgagtt tcgactaccg
    18061 acaacgaact cttggaacag actgcaggaa atatctttgc ttctgtcaaa aatccatatc
    18121 tgcaagcaag tgaatggggg tggcaaattg atccattagg cttgagaata acgatgaatg
    18181 atatttatga tcgttatcaa aaaccattat ttattgtaga aaacggctta ggtgcagtcg
    18241 atacgccaga tgagaatggt tatgtggaag atgattaccg aatcgattac ctggcagcgc
    18301 atatccaggc gatgaaggat gcagtagaac tagacggagt cgatctatta ggctatacga
    18361 cttggggatg tattgattta gtatcagctg gtaccggtga gatgaagaaa agatacggat
    18421 tcatttatgt cgatcgtgat aaccaaggaa atggcacatt agcccgttca aagaaaaaat
    18481 cattcaactg gtataaaaaa gtaattgatt caaatggaga aaatctttcg aacgattgat
    18541 caatgattta taaaagtcta ttgtttttca gcggattttt cgagtataat aaagctattc
    18601 gagaaacgca agcagaacaa tagacttttt ttcgcattgg ctgtaaagta tgcttacttg
    18661 attaagtaaa ggagaatcta catatgtatg atgtaatcgt tattggcgca ggtcctgctg
    18721 ggatgactgc tgctttatat gcttcacgtt caaacttatc cgtattgatg atcgaacaag
    18781 gtgcccctgg cggccaaatg aacaatacgg cagaaatcga aaattatcct ggattcgatt
    18841 cgatcatggg ccccgatcta gcttataaga tgtatgaaag tgtctcaaga tttgggacag
    18901 aaaatgctta tggaatcgtt caagatatca aggatcacgg cagccataaa gaagtcatct
    18961 gtgaagataa aagttacgaa ggaaaaacag tcattatcgc aacaggctgt atccaccgta
    19021 aattaggcgt acctggcgag gaagaatttg ctggacgagg cgtttcttac tgtgcagtct
    19081 gtgatggtgc gtttttccgt aacaaacgtc tagtagtcat cgggggtggg gactcagcag
    19141 tagaagaagc catctatttg acacaatttg cttctgaagt agtgatcgtc caccgtagag
    19201 atgaattacg tgcacaaaag atcatccaag accgtgcatt tgcaaatgaa aaaatttcct
    19261 ttatgtggga tacagtcgtt gacgaaatcg ttggaaacga aatggtagtg acaggtgtga
    19321 aagcacgtaa tgtcaaaacc ggcaatgaat ttgatttagc agcagacgga gtattcatct
    19381 atgttggact ggatccatta actgcacctt ttagagaagc aggtttgacg aacgaagctg
    19441 gctggattcc aacagacaac gaaatgaaaa cgaatatgcc aggcgttttt gccatcggag
    19501 atgttcgtga aaaagatttg cgacaaatca ctacagctgt tggtgacggc ggtattgctg
    19561 gacaacaagt gtataaatac ttggaatctt tagaagaaac aactgcataa gtttaaaaag
    19621 agtagaagaa cgggttcaat tgttctttta ctcttttttt tcgcgtgaaa tttactgaat
    19681 ctgatttatg cgaacacgtc caacaccttt tgataaaaga atcctttctt gatttaagcg
    19741 ttttttggtc ctcatacttt catatctaat aagtgaatgc tatacttatt aagaaccata
    19801 tttcagaaag aggtgttatt ttcatgtctt gggaacaagt gtatgaacaa tgggtacatg
    19861 aagaaaattt agaagaaaac ttaaaaaaac aattaaatga tctgggtgaa gatcctgaaa
    19921 aacttgaaga tgctttttat gcaccgttgg aattcggtac tgcaggcatg cggggaatct
    19981 taggacctgg gatcaatcga atgaacatct atacggtaag acaagcaaca gaaggactag
    20041 cacgtttcat ggatacacaa ggtgaagaag caaaacgccg aggtgtcgct attgcttatg
    20101 actcacgcca tcagtcacca gaatttgcaa tggaagcagc caaaacactg gcacatcaca
    20161 atatcccgtc ttatgtattc gaaagtctgc gtccaacacc agagctttct tttgcagttc
    20221 gtcatttgaa gacgtttgcg ggaatcatgg taactgcatc tcacaaccca gcggcttaca
    20281 atggatataa agtctacgga gaagatggcg gacaaatgcc tcctgcagac gcagatgcat
    20341 tgacgaaata tgtccgtgaa gtcagcaatc cgctaaaagt cgaagtatta tctgacgaag
    20401 aagctaaaca tagcgggttg atcacgatca tcggagaaga agtggacgct gcttatctag
    20461 aagaaatcaa agcagtgacg attgatcgtg aattggtaga aacaatgggg aaagatttga
    20521 aacttgtgta cacgccactt catggaacag ggaaaatgtt gggcgaacgt gcgttgaaac
    20581 aagctggatt cgaacaattc gtactagttc ccgaacaagc tgtggcagat ccagatttca
    20641 ctacggtcaa atcgccaaat ccagaagaac attcagcttt tgaatatgct atacgacttg
    20701 gagaaaaaga aggagctgac ttgctgattg caacagatcc tgatgcagac cgtttaggcg
    20761 cagcggttcg tttgccagat ggttcttatg aagtattgac tgggaaccaa atcggggcat
    20821 tgtttgctca atatattttg gaagcacatc aatcaagagg cactttacca gaaaacgcag
    20881 cggtattgaa atcaatcgtt tccagcgaat tgcctacagc aattgcggaa cactacggtg
    20941 ctaccatgtt caatgtgttg acagggttta aattcattgc tgaaaaaatc caacaattcg
    21001 aagaagacca ttcacatact tttatgtttg gattcgaaga aagttatggt tatttagtta
    21061 aaccttttgt tcgcgataaa gacgcgatcc aagcattgct tttattagca gaagtagcag
    21121 cttactataa aaaacaaggc aaaacgttgt atgacggctt gcaaacgatt tttgaaacct
    21181 atggctattt tgcagaaaaa acgatttctg tgacaatgag cggacaagaa ggttctgcga
    21241 aaatctctgc tttgatggaa aaattccgta aagaagcacc gacagaattt gccggagcaa
    21301 aagttattca aacagaagac tttaaagaat tgacgagaac agaccgtgaa ggaaacgtag
    21361 aaaaactaac aacaccgcca tccgacgtat tgaaatatac attggaagaa aatggctgga
    21421 ttgctatccg cccttcagga actgagccga aaatcaagtt ttatattggt gtaaaaggaa
    21481 gctctacaga agacgcagcc gaaaaagtag cctcttatga agcgattatc aaaaagatga
    21541 cagaagaata aaaaacttga gactgatgga aaaagtggta aactttagaa gtcagtcttt
    21601 tttcaagttg gaggtgaatg gattgccaga cacgcaaaaa tcaaaagtag agaaagtcag
    21661 tcaattattc aaaatgttga gtgatcccac tcgtcttaaa attctgctat atctgaaaga
    21721 cggggaacaa aatgtgacag caatcaccca agcagtggaa atggagcagt ctgctgtatc
    21781 gcatcaacta cgtttattaa gagaaaatca tgtcgtcaag tctcatcgcg agggaaaagc
    21841 gattttgtat agtcttgatg attctcatgt actggatatt ttgaaccaga cactcaaaca
    21901 tgtggaacat caataacgat aggtgcaaat agataaacac tggagtgtga caacgaaatt
    21961 tcttcgttgt cacactccag tgttttttaa gaaaaagaca aaaatgatta atcgcttttt
    22021 tctgttgttt cagttccata ataactatga tcttctaggt ctaaagcatt caaaataagc
    22081 gaagccgttt cttcaataga taaagatgcc acattgatca ctacacatcc tagtttttca
    22141 taaagatcat tcgcaaaatc gagttcagct ctaatttttt cgatatcgga ataagcagta
    22201 tcagggttta atccgtaaga gcgcatccgt tctttacgga tattatttaa aatatctggg
    22261 ttattcgtta gtcccacgat ttttttagga tcgatctccc aaagctgttt gggaatatgt
    22321 gcttgtggga tcaaaggtaa attggcaact tttaaatttt tgttagctaa aaacaagctc
    22381 aaaggcgttt tggaagttcg ggatacgcct agcaaaacga catctgcttc taaaaaacca
    22441 cgaggatctt tcccatcatc gtattttaca gcaaattcca ttgctttgat ccgtttgaaa
    22501 tagttctcat tcaataaatg gagggcacca ggttgccgaa ttggcttgat accggttaaa
    22561 cgttcaattt ctgatatcgg tggcgtcatc acatcaaaac taaataattg atgttcttca
    22621 caaaaagaac gtgttatctc gatcagttct tgattgatta atgtatgcag gacaagtgct
    22681 ttttcttcta atgcatcttg caatgcctgc tttaatgttt tttcatctgt cacgaacgtt
    22741 ctgcggaata ggttgaactc aacggtagga tactgagcca tagtagcttg cgctagtttt
    22801 gtcgcagttt ctccagcaga gtcggagatg acaaaaaaag taacgatttc tgtagaatcg
    22861 gaagacatgg ataaaacctc acttgcattt tttttatgtt tattatacca tactctagaa
    22921 tgcgtacttc gtaatcattt tgatttggag gaataagtca tgaaaaaaca gacattgatc
    22981 gaacaatcat tagaaacatt gaaaaataac ggttttaaat atactaaaaa aagagaagca
    23041 ttgttaactt atttagtgaa gcgtaaccgc tacgtatctg ctaaagaagt ttttgactat
    23101 atgaatcagg aattcaaagg ggtaagttat gatacgattt atcggaatct ccatgatttt
    23161 gcagagatcg atttactgga agaaaccgat ttaaatggag aaatgaagtt tcgttttcat
    23221 tgctgtcagg gggaaatcgg ccatcaccat cattttatct gtacagtgtg cggaacaacg
    23281 aaagaaatcc atatgtgtcc gatgaattat ttcgaagaac agctaggtgg atgcacgatc
    23341 gaagggcata gattcgagat tttcggaaga tgtgaaaatt gtcaataagg gtttaaataa
    23401 aataacattt gataatttta aaaaaaagca agatttcctt gacggtcaaa acagcattag
    23461 atataatatt tacaggacag tcttgttttt tgagatatat ttcaataaca attacggtta
    23521 ctttttaagc tcggagggag ggaattaaca tgtcaaaaac agtcgttcgc aaaaacgaat
    23581 cacttgacga tgctcttcgt cgcttcaaac gttccgtgtc aaaagcgggt actttacaag
    23641 aatctcgtaa acgtgaattc tacgaaaaac caagtgtaag acgcaagaaa aaatctgaag
    23701 cagctagaaa acgcaaaaaa ttctagttct gtgatgaatt ggagttggta gtgtgtcact
    23761 actaagtaga ttaaacgatg acatgaaagc agcgatgaaa gcgaaagata aggaatcttt
    23821 acaagtcatc cgaatgatca agtcatctat acaaaacgag cagattaaag aaggtcacga
    23881 cttgacagaa gaagaagaac taacggtgtt gtctcgcgaa atgaaacagc gacgtgattc
    23941 tttgcatgag tttgaagaag caggacgtga cgatttagct gaaaaagtaa aaagtgaaat
    24001 tgtaatagtc gaaaaatata tgccggaaca actttccgat gaagaaattc gacaacttgt
    24061 tcaagaagca atcactcaaa ctggtgcttc atcaatgaaa gaatttggca aagttatggg
    24121 tgcaattatg cctaaagtca aaggaaaagc agatggaaac caagtgaatg cgattgtgaa
    24181 agaactatta caatcttaat tttatcattt aaactgcgga cagtgattgt ccgcagtttt
    24241 ttgtgttcgt aaaaaaagaa ctaaaaa
//
LOCUS       DBBGSP010000045        24258 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000045 DBBGSP010000000
VERSION     DBBGSP010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.045"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(44..1339)
                     /gene="purB"
                     /locus_tag="ACIZE9_002085"
     CDS             complement(44..1339)
                     /gene="purB"
                     /locus_tag="ACIZE9_002085"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGC6093931.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAATGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1352..2476)
                     /gene="purK"
                     /locus_tag="ACIZE9_002086"
     CDS             complement(1352..2476)
                     /gene="purK"
                     /locus_tag="ACIZE9_002086"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGC6093932.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2469..2957)
                     /gene="purE"
                     /locus_tag="ACIZE9_002087"
     CDS             complement(2469..2957)
                     /gene="purE"
                     /locus_tag="ACIZE9_002087"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGC6093933.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3372..4679)
                     /locus_tag="ACIZE9_002088"
     CDS             complement(3372..4679)
                     /locus_tag="ACIZE9_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGC6093934.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4682..5263)
                     /locus_tag="ACIZE9_002089"
     CDS             complement(4682..5263)
                     /locus_tag="ACIZE9_002089"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGC6093935.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5379..5476)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5835..7127)
                     /locus_tag="ACIZE9_002090"
     CDS             complement(5835..7127)
                     /locus_tag="ACIZE9_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6093936.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7124..7747)
                     /locus_tag="ACIZE9_002091"
     CDS             complement(7124..7747)
                     /locus_tag="ACIZE9_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093937.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7750..8586)
                     /locus_tag="ACIZE9_002092"
     CDS             complement(7750..8586)
                     /locus_tag="ACIZE9_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6093938.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8603..9490)
                     /locus_tag="ACIZE9_002093"
     CDS             complement(8603..9490)
                     /locus_tag="ACIZE9_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6093939.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9506..10789)
                     /locus_tag="ACIZE9_002094"
     CDS             complement(9506..10789)
                     /locus_tag="ACIZE9_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6093940.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11472..12155)
                     /locus_tag="ACIZE9_002095"
     CDS             complement(11472..12155)
                     /locus_tag="ACIZE9_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HGC6093941.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12173..12790)
                     /locus_tag="ACIZE9_002096"
     CDS             complement(12173..12790)
                     /locus_tag="ACIZE9_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HGC6093942.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12800..13624)
                     /locus_tag="ACIZE9_002097"
     CDS             complement(12800..13624)
                     /locus_tag="ACIZE9_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HGC6093943.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13617..14177)
                     /locus_tag="ACIZE9_002098"
     CDS             complement(13617..14177)
                     /locus_tag="ACIZE9_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093944.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14351..15307
                     /locus_tag="ACIZE9_002099"
     CDS             14351..15307
                     /locus_tag="ACIZE9_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6093945.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15612..16568)
                     /locus_tag="ACIZE9_002100"
     CDS             complement(15612..16568)
                     /locus_tag="ACIZE9_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGC6093946.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16672..17274
                     /locus_tag="ACIZE9_002101"
     CDS             16672..17274
                     /locus_tag="ACIZE9_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HGC6093947.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17362..18861)
                     /locus_tag="ACIZE9_002102"
     CDS             complement(17362..18861)
                     /locus_tag="ACIZE9_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HGC6093948.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18877..19401)
                     /locus_tag="ACIZE9_002103"
     CDS             complement(18877..19401)
                     /locus_tag="ACIZE9_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HGC6093949.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19699..20448
                     /locus_tag="ACIZE9_002104"
     CDS             19699..20448
                     /locus_tag="ACIZE9_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HGC6093950.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20439..21224
                     /locus_tag="ACIZE9_002105"
     CDS             20439..21224
                     /locus_tag="ACIZE9_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6093951.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21193..21909
                     /locus_tag="ACIZE9_002106"
     CDS             21193..21909
                     /locus_tag="ACIZE9_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC6093952.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22011..23030)
                     /locus_tag="ACIZE9_002107"
     CDS             complement(22011..23030)
                     /locus_tag="ACIZE9_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HGC6093953.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23049..24050)
                     /locus_tag="ACIZE9_002108"
     CDS             complement(23049..24050)
                     /locus_tag="ACIZE9_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HGC6093954.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
BASE COUNT         7188 a         5222 c         4226 g         7622 t
ORIGIN      
        1 ttttgctatt ctattttaat tgaattttgc aactcactct tctttattcc aaacctactc
       61 gtttgaatat cacgtcaacg tttttcaaat gatgatgata atcaaaggca tcgtctattt
      121 cttctttaga taataccgat gtgatggttg gatcttcttc taacagcggg cggaactgca
      181 cttggttgtc ccaagcgtac gcagtttttg gctgaacaag atcataagct tcttctcttg
      241 tcattccctt atcgatcaat ttcagcataa cgcgctggct ataaatcaaa ccaaatgttg
      301 cagacatatt ccgcttcatg ttttcaggaa agaccgttag atttttaacg atattgccaa
      361 aacgatttaa catgtaattc aataaaatcg tggtatcagg caagatgatt cgttctgctg
      421 aagaatgaga aatatctctt tcatgccata atgtgacatt ttcataggca gtgaccatgt
      481 gtccgcgcac cactctggct agaccagcca tattttctga accgatcgga ttccttttgt
      541 gcggcatagc agaagaacct ttttgacctt tcgcaaaaaa ttcttctact tcacgtgttt
      601 cggatttttg caatccgcgt atctctgttg caaaacgttc aatacttgta gcaataagcg
      661 ccatcgctga gaaatattca gcatgtagat cccgagggag aacttgagta gagatttctt
      721 gtggacggat ccccaattgt ttacatacat actcttcaat aaatggcggg atatttgcga
      781 acgttcccac tgctcctgag atttttcctg cttctactcc tgttgccgca tgttcaaatc
      841 gttcgatgtt ccgtttcatt tctgaatacc atgtggcaag tttcaatcca aaagtagttg
      901 gttcagcatg gacaccgtgt gtccgaccca tcatcactgt atatttgtgt tcttttgctt
      961 tttcgccaat gatttccgta aaacgtttca agtcttcccg taaaatatca tttgcttgct
     1021 tgatgagata gccataagca gtatctacga catccgtact tgttagacca taatggaccc
     1081 attttctttc ttctcccaat gtttcagaaa ccgctcgtgt aaacgcaacg acatcatggc
     1141 gtgttaattt ttcgatttcc aagatccgat cgatatcaaa tgatgcatgc tcacgaattt
     1201 ttttcacatc ttcttgcggg atttcaccaa gttctgccca agcttcatct gctaaaatct
     1261 cgacttcgag ccacgcacgg tatttgttct cttccgtcca gatattcccc atttcagggc
     1321 gtgtataacg ttctaacatg ttttttctcc tctaatccca aatattcgtt tgtttgattt
     1381 cttccagcgt ttgctggatg tcttctgtca agatagtgat atgtcccatc ttgcgacctt
     1441 tttttgcttg tttttttcca tagaaatgga attgccagtc tggcttattc tcaatcaagc
     1501 gatagctttc cagcagttgt tctcccaaaa cattgaccat tactgcattg cttatcaaac
     1561 gtactttttc tcctaatggc caaccacaaa tacctcgaat atgggcatcg aactgactca
     1621 tagaacaagc ttcaatagaa taatgtccag aattgtgagg acgaggagct aattcattca
     1681 catatagccc gcctgttttt gttaaaaaca tttctacccc taaaacacct gaaaggctca
     1741 ctgcttctgc aatcacacgg gcaatacgct cagcctcctc gatcacatcc tgatcaatcg
     1801 cggctggagc aatcgtttca tgaagaatat tgttgtggtg gatgttttcc acgaccggaa
     1861 aagtcgtgaa atctccttga ccatttcctg ccaccatgat cgaaatctct ttttcaaacg
     1921 ggatccatgc ttctaaaaca caggttcctt ctcttaaaag gtccatggca ggagctagat
     1981 ccgcccgact tttcaaaaca tactgcccct tgccatcata gccgcctcga gtggttttca
     2041 aaacacaagg atagccgatc ccgtcaatcg catcttggat atccgtcgga ctgacgatcg
     2101 ttgcataagg agcaatcacg atgttattcg tttccaaaaa agatttttct aacaggcggt
     2161 cttgcgtaat cgcaagcaag tctgtccctt gaggaataaa tgacatgggt aaaatcgcat
     2221 ttaacgcctc tacactgacg ttttcgaatt cataggtaat gacatctgtt cttctggcaa
     2281 gctctttcag cgcaaaggtg tcatcataga cactttcaat gtgccaatct gcaacttgtg
     2341 cggctggaca atcgctcaca ggatccagca cacctacttt aaagcccatt tcttttgcac
     2401 taatcgccat catacgacct aattgaccgc caccgacgat cccgatcgtt gaaccaggca
     2461 acaaaggttt aaccaagttg atcactactt tctataacag ttttagccaa cattgaacgt
     2521 ctttcagcca atttagcctc caattctaaa tcatacatgg aaagcatctg tatcgcaagt
     2581 agtccagcat taattgctcc cgcttttccg attgctgtag tagctacagg tactcctcca
     2641 ggcatttgga caatcgaaag aagcgaatcc aaaccattta atgttcgtga ttggaccggt
     2701 acaccgataa ccggcaaagt tgtttttgat gcgaccatac ccggcagatg cgcggctccc
     2761 cctgctcctg caataatgat tttgattcct ttttttcgag cgttttgtgc atattcaaac
     2821 atcaaatctg gggttcgatg agcagaaacg accttttttt cataagacac accgaattca
     2881 tccaatattt gacatgcttc tttcattgtt tcccaatctg aagtactccc cataatcaca
     2941 gagatttttg ctgtcattgt ttttcctccc agtttttcta cattcatatt ttaacaatca
     3001 ctttttttga tgtcaaagaa atttcgaatg ttaacaaaga aaaacatttt attgttcgtg
     3061 tttattaaag ataaaaaaaa ggaatgtgac aaaagttagg tcacattcct ttttatggat
     3121 aaacggtgtt ctcctgccaa ctcctcggtc acaaggaaca atattcaaca aacatgagaa
     3181 gctttttttg aaattgttcc ttgtgactcg gagatgaacg gcaggctcac gacctcttcc
     3241 ttcaacggtg ttcaatcagc tgaccctcgg tattagctca aacaaacggc aaaatacgag
     3301 gaactatttt tccgtttgtt tctctaacaa tcaggtcaaa acgctgattt cacaaccttt
     3361 cttttgctct attacttctt gaaggcttct tccaatattt cttcatcttt tttcaatcca
     3421 ttaaagatca aattcaatat gatagccgta atgctactca ttacgatgcc atttccagtg
     3481 aacatttgca atgtttgcgg catttgactg aataatgtcg gcgtaacatt gaaacccagc
     3541 ccaaatccaa cagaaacagc aacaatcaat agatttttat cattgctgaa atcaacttcc
     3601 aacagcatac ggattccttg gactgccacc atcccgaaca tgactaacat tcctccacca
     3661 agtaccggct cagggatgat ttgtgctaac gcaccgattt tagggaataa tcctaaaaca
     3721 atcaagaaga atgcagagaa atagatgggt tttcttgttt tgattcccga aagttgaacc
     3781 aatccgacat tttgagaaaa gccagtataa gggaatgtat tgaaaatacc gcctaagata
     3841 acggcaagtc cttctgcacg atatcccttt ttcaattctt cttctccaac atttttccca
     3901 gtaatgtcac caagtgcaaa atatacacct gttgattcta ccatgctgac catggaaatg
     3961 atgatcatta gtaaaatcga ccatacgtcg aaagttggtt taccaaaata aaagggttgt
     4021 ggaacatgga acaacggcgc atctccaatc gcgctcagat caatcattcc catgaaagca
     4081 gctaagatgc ttcctccgac taaaccaatc aataccgcga ttgaacgaat gaaccctttt
     4141 gccagcattt gcacgcctac aattaggaga atcgtcacaa atgcaagtag cagatttgtt
     4201 ttgtcaccaa aatcagctgc tgttgcatta cctccaccca ttttctcgat tgctacagga
     4261 atcaaagtca aaccaataac ggtgataacc gttcctgtta ctataggagg gaatagtttt
     4321 ttaattttag aaaagacacc agaaactaac acaacaaaga tcccagaagc gataatagat
     4381 ccgtagatag ctcctactcc ttcattggtt ccgatcaaga tcagtggagc tactgcttgg
     4441 atcgcacatc ctaaaacgac aggcaagcca attccgaaaa atcggttaac tgtcaattgc
     4501 aataatgtcg ctaatccaca cataaagata tcaattgaaa tcaaataagt catctgttct
     4561 tgattaaagc ctagtcctgt accgatcaaa agaggcaccg ctactgctcc tgcatacatc
     4621 gctagcagat gctgcagccc taaaaccgca gcttttccat tttgtgtttc tttttccacg
     4681 attatgcgtc ctcctcaaga aactcaactt gtccattcgt caaggaagca atacgcgcaa
     4741 gagaaacgac tctcaatccc atttcttcaa gtaactgacg tccatcttgg aaagactttt
     4801 cgatgacgat cccgattcct tctacttgcg ctccagcttg ctggcataat tcgatcaatc
     4861 cttttgccgc ttgtccgttt gccaagaaat cgtcgataat caatactttg tcttctgaag
     4921 ataaaaattt acgagaaata gaaatcgtac ttgtcacttg tttcgtaaaa gaataaacag
     4981 aagctgtcaa taattcttca tccatcgtca aactttttgc ttttctagcg aagatcattg
     5041 gaacatctaa ttctcttgca gcaaataaag ctggtgcgat cccagaagct tcaatggtca
     5101 caactttcgt gattccttgt tctttaaata cttctgcaaa ccgttttccc atttgttcca
     5161 tcaatacagg gtctacttgg tgagtgacga agctgtcgac ttttaatacg ccctcgccta
     5221 atatacgtcc gtctttttga atacgttcaa ctaattcttt cactttattt gctcctttat
     5281 catttattaa taccgaaata accgcttttg tgcaaaaacc tactatgttt ctgttaaaga
     5341 aaaacaccct ccactttatc ataagaaaag aagggtgaaa tagccaatct tttacttata
     5401 gtccagcatt tacggtactg gctagaaact gtcatccata ttatgacgat atataagtag
     5461 gtatgtaaaa ctaataatag tgtaaattca ttttcttgca actgttttgc acgtgaaggc
     5521 agtttgccat atttgaataa aaaatgttgt ttcaaatatt gaaaacagtc taacactact
     5581 ttctgaaact gacaacgtgg tttacttatt tttttgtaaa atctaatgat ttttaatgca
     5641 ttattccttt ttgttcgggt ttaaatagtt atttttattt tctcctatct aaaaaagcag
     5701 cccacataaa aagaaggcat gacaaaaagc atgtcatagc ccctttttcc gaataaatag
     5761 tgttcaaaag acagcctatc ggcaataagg caagatttta taaactacgg gaagtaattt
     5821 ccgtaaatct attcttattc ttttaagctg acaagctcgt caatcactac tgcttttcct
     5881 gaagcaatag aatgatttgc tgcgattcct gtcaaaatcg acaaaatacc atctacgtga
     5941 gttgctgccc gattccacgg atcttcttct ttttcttcac caaatagatc atctaataaa
     6001 cgcggatctc ctccgccatg tccgcccgct tcttgttcga cgattacctc atatggctca
     6061 ccgaacatcg gatagacatg gatggactga agaacggctg ctccttcatc ctttttatct
     6121 ccacctgcat tgatgtaaga cttttcgatc actttcattt cgatccgtcc tttgctgcca
     6181 ttgaaagaaa cattgaatcc ttcccacggc atatacgcgt ttagcgaata cgtcaaaatc
     6241 gcaccagttt catatttgac cgttacgcct agtgtatctt caatagagat atcatcggaa
     6301 aatacactgc ggtcacgaat atatccactg tctttttctg cttctaaata catttctcgc
     6361 aattcctcat tggctgacag gtctatagca aatggatcag ctttagctag ttcgcttcca
     6421 tagcatcgac tgtaaaatat ttctactccg cgtttctccg cattatgcat cccataaaag
     6481 tttaatccac cgaatgcaaa taccttttgg ggacggctgt tcaaccaaaa attcactaga
     6541 tcaaaatgat gggtagattt atgaacaaga agcccgccgc tattgtgctt atttcgatgc
     6601 catcttctga aataatctgc cccgtgttgc gtatttaaca gccattcgaa gtggatagaa
     6661 aacacatcac caatcacatc actttctatc agttccttta tcttcgtgtg atacggtgca
     6721 taacgataat taaaagtgac tcgcaggctt cttcccgtct gtttttggac cgttattatt
     6781 tcttgagctt tttcctcatc gatagtcaga ggtttttcgc aaataacatc atatcctttt
     6841 ttcattgcac gaatgatata atcatgatgc gttcgatcta ctgacgtaat aatgacttca
     6901 gccggccgta cgtcatccag tagttgctca aattgtgatg gcatacatgt ctttactttt
     6961 ttctgtccat acttgttcac aagtatccga tttgcataat ccatccttgt ttgagataca
     7021 tcacaaaaac cgactagttc acaagtttga tgatacgtag aggcaattgc ctcataaaaa
     7081 aaacgcgctc tcccaccaag tccgacttgt acatattttt tcttcattta aagtcattct
     7141 ccttttcttt taagcaaaat actgtgacaa atggcagccc tggatacagt aatgcagtga
     7201 gtaaaaaatc atgctgtata caccagaaca gtccatacaa aaggcataaa taccacagaa
     7261 accccttgac gttttttgac aacagccaga tattcctttt gatcaaataa acaagactat
     7321 ctgctttatc ttctttgcag atatcaatta gcgtactaaa aaaactatgg gatacaaaaa
     7381 gcaacagaca caatagaaaa ggaatcagat accaagctcc aatctttccc actaataaat
     7441 accaatcaac tgcaaaaata atgacaaaca gctgaaacaa cgtaatgatg aaacacatcc
     7501 gtttgatttt tcctttcctc caacatacct ttttttctgc caagtaatgg acagatagat
     7561 aataagaagg atacatcatc aaaaaataaa tcagatagac aacacgagca gacagcacta
     7621 atcctaaagt gaacaaacat cctagaacta aagcgaaaag agcattactg ataagactgg
     7681 ttaaaaaaat ccgacagaca tagtagttga gcttgtaaag aaacatctct tctattggct
     7741 ttttcatatt cagcccttca gaccgcttgt actgatcccc tggacaagat atttattgaa
     7801 gaataagaaa atcagaaaaa ccggtagcag cgacaacgta gacatcgcaa acatactcgc
     7861 gtaagtcgta ctagatccag cgtctgcaaa taatttgatg gcaatcgata ccgtgtaaga
     7921 tctcggcttg tttaaataaa tcaatggtcc catgaagtcg tcccatttcc aataaaactg
     7981 gatgatgatc gtcgtgatga tcgaaggttt cagcaaagga aaaataattt tggtaaagac
     8041 actatacttg ctgcatccgt caataatcgc tgattcatct aactctttgg ggatgctgac
     8101 catgaattgc atgatctggt aaatgaaaaa tgcttgtcca aaaaaatgtg gtaaaatcag
     8161 cggcacatac gtcccaacca aattcagccg attgtaaata ataaactgcg gaatcaaaat
     8221 cacttgtgca ggaatcatca tcgttactaa catgacgacg aaccagaatc tttttccttt
     8281 gaaatcgatt ctcgataatg cgtaagcaat acaagtcgag ctcagaactg tccctatcgt
     8341 cgaaactgca gagatgacaa acgaattcct aaagaaagta aaaaatgaaa ttccagcaaa
     8401 ccccgcccat ccttttgcgt aattttccca ttgaaaagtc tctggaatca aattcagcga
     8461 accactcata atctcttgat ccgttttaaa agaacctgcg atcatccata agaccggata
     8521 aatcatgact agacctaata gcaaaataaa accgtattga aaccatttcg ttactgtatt
     8581 attcatttct tcctcctctc attcacacaa cgacccattt ttttgatgat ttgaaaatca
     8641 gaaaggtgac agctcccata atcaacagca tgatccacga aatagcacta gcatacccca
     8701 tagaattaaa agaaaaagct tggttataca cataaagagc ataaaagttc gtggcatcat
     8761 tcggaccacc ttgggtaatg ataaatgcct gcgtaaaagt cataaacgcc gcgattgtct
     8821 gcataaccaa gttatacaaa atgatcggcg aaagaagagg taacgtgatc ttgtaaaacg
     8881 tctgccattt gttcgctcca tcgatctctg ccgcttcata atacgagcct gggatctctt
     8941 tgatacctgc agcaaagatg atcattgccg aaccgaattg ccaagcagac atcaaaacaa
     9001 gagggatcat gaccagtttt tgatcgctaa accaggaaag cgcaggtgcg cctaatcgtt
     9061 ccaggaaaat attcactaac ccgtttttag aaaacaactc ccgccaaact agagcgatag
     9121 aaatactgcc accgatcaaa ctaggcacat aatacaaaga acgaaagaaa gtcgttcctt
     9181 tgatattcct cgttaaaaga taagcaatca atagaccaaa gatcagtttc acaggtacag
     9241 atgcaaatac atagagaaaa gtgactcgga tggagttcaa aaaacgggca tcactcagca
     9301 tctttatata attatccaag ccgatccatg agactggatt tcccaaacga taatcggtga
     9361 acgaataata aagtgacaag atcatcggta tcactgttat caatagaaat cctaggatga
     9421 atggagaagc aaatacgtaa ccgaccacat tgtcttgatc caagaaccgt tttagttttt
     9481 cttttttcat gccttcctcc tgctgctatc ctagaatgtt tgacgcaaac tcataaagac
     9541 tctctgctgc ttcttctgct gttacttctt cataaatgac tttttcaact aaaagattgt
     9601 attggtcttg aatttccgga ttcaaagcac tatcaaagac attcacttcg ccgttgtcca
     9661 tatcggaaat catttctaaa taatcaaatg tcgcttgcaa agttgcatca tctgcacgag
     9721 cgagctgttc tcgaatattc gacatgattg gtacaccacg ttctcctttt aaaatttcat
     9781 tggcttcttc actgttttga aagaaatcaa taaacttagc agcttcttct ttatgggctg
     9841 agctttttgc catactcagc atttgcgaag aacgtaaagg gataccagat tctccatctg
     9901 cttttctgcg aggtggatta atcaactgaa tctccatatc ttcaggagcc cctgacaata
     9961 tttctgtcaa ctggttactt gatagaaaca ccattgccgc ttctctatcc ctaaccgcct
    10021 gaaaagacag atccgtcgta cttgcagctc caccacctgg ttctggatgg gcccctttgt
    10081 ctaccagatt tttacgcagc tggaaaaaat ctgttagata gtctggattt tcaaatccca
    10141 agctgttaga tagatcttcc cgattataaa aattcaatcc tttctcaact tgtggtattt
    10201 gaataataca gccagctata aaatcttcga atcttgaaat agcatagatt cctaattctt
    10261 cagtgatttg atagctgatt tgttcaaatt catcccatgt ccaatttgaa gctggttcag
    10321 ggatatttaa ttgttcaaat atatttttat tgtaagcaat cgcaaacgaa ttcaccccgt
    10381 tagacagtcc aactaattgc ccgtcgtaag tcgtcgttgc taaataggat tcatctgcat
    10441 tagaaatatc aattatccct tgctccacat attcatctaa tggttcaatc tgattgatgt
    10501 attgaggaaa ttgattgttc agttggaaaa tgtcccagat atcatctgat gctgctagtg
    10561 tacctaattt tgtgtaatat ccttcataat cataaaattc ataatcgatc gtcacatggg
    10621 gatttttttc ttcataaagc tcgattactt ttactgttgc atcgtgtcgg acttgcgaac
    10681 cccaccaagc catgttcagc gtgatttttt tgtcatcttc ttgcccacaa gccgtcaaga
    10741 agaataacat aacacttaaa gctaagatga ttctcattct tttcttcatt ctctgcacct
    10801 ctacttccat tgttattttt caatatactg tatttttata cagaacatat ttattaaacg
    10861 atctttttca aggggaataa aaaccaagac ttgccttatc gttctgccta ggatgaacaa
    10921 ctcaatactt tcaagaaaaa ttagatagtg ctgattcttc tttcatcgct aaaaacactt
    10981 cttgcttcaa tgatgggagg ataattacgc aaagaaaaaa ggatatcaga caactgccca
    11041 atatccttga catagctaaa taagcatgct tcttcgtgtg cgctcttccc taaaaaacag
    11101 aaaaataact agtaattctg tatgaaatta ggtacaatat acacgtcgat gcacaagcat
    11161 tgactatggc aacttgattg gtcagttccc gctgactttt caagccccga caatttagct
    11221 gctactaaat tgtcgggtgc cttttttagt ttttattcgt ttttcattct atagaaagcg
    11281 cttcaataaa tcaagacatt tttttgttag aatgctaata ataacaaaag gttttaactc
    11341 ttcttatgta cattacaggt aaaaaaacaa aaaaatttct cttttttttg aattctgaac
    11401 aaatagtact ggagtacaaa agacgaggaa gagccactat ctgctcttcc tcgtcttttg
    11461 attctcacct gttattcatg attctttttc tcagtttccc gatatttttc cattttacga
    11521 ctaaaaagct ctccgctact tggtggcgta tatgtgatgg catttgctcc tgcttgaatg
    11581 gtctcagcaa tactttcttc cgttggacca cctgtcgcaa tgataggaag ttcaggatat
    11641 tttttacgaa aatggcgtac tgcttctgca gtttctttac ctgcactgat attgataatc
    11701 gaaataccag ctgctaactt ttcatctatt tctgtatatt tcgacgttac cgtactgata
    11761 actggaatat caactactcg acaaacttct tttactgtct ctaaaggcgt aggaccgttc
    11821 aaaacgaccc ctaacgaacc ttgcgcttct gcgaacatgc tcatgtagga agaacgagca
    11881 ccttgtgtca aaccaccacc tacaccggag aaaactggaa tgtcagctgc ctcaataatg
    11941 cttttagtaa tcgctggatg aggtgtaaaa ggatacacag caattactgc attcgcattt
    12001 gtattacgta tgatcgcaat atccgtagta aagatgatcg aacggatcaa ttttccaaat
    12061 atcttgatcc cgcttgcttc taaaatgatt tccggtactc ttacgatatc ttttctcaat
    12121 tccgtcatga tttctggcgt aaattgttct gccatcagcc acttctcctt tgctatctcc
    12181 ggtcatactg attcaattga tacgtctcga tgacctggat gattttttgc gcataaccgg
    12241 ggtctgtcgc ataacctgca tcttgcaatg cttgtgcggc ttcctgatag ttggtggccg
    12301 taatcacttt ttcatacagc gcaggattcc aatctactcc ttggacgaac agttgtgtat
    12361 ggtcatccat ggactgttcc catgaatcat acactttgaa gtctccttgg atagttatcc
    12421 attcttcgtt aacaaattcc tttgtttcca ggcttacttt cttctgatcc ccataagcct
    12481 tgatcccgaa aagattattg tatttgctag ccaaggtact ttttccccaa tttgattcta
    12541 atatagcttg tcctaaaatg atactaggaa gcactccata accatcttgt agttcttggg
    12601 catgcggaac aagccgttca ataaattgct gatgggattg cgcttcattt tcttgctgat
    12661 tatcagtaaa aggagaagac agattcttca aggaaaaaac aaaggctaag agtatcactg
    12721 ctacaccggc aaccactgct ggccaacgga tattcttgcg cttttgcttt ttccactttt
    12781 ttttcgccat gatcaattcc tacttttcat ttaattcatt cagatattct tctagcgtca
    12841 attggtgttt ggtgatatac tcagcgtttt ctttaccgac ataacgtaag tgccaaggtt
    12901 catatgtgat cttagttata tcttcgtgtc cttttggata acgaacgata aatccatact
    12961 gcgcagcatt atctgcgatc catttagctc caggctgatc tccgtaactt gcatccaata
    13021 cagtagaagg ataactgttg taccagtttt gatcgacgac atcgactgcc agacctgtgt
    13081 ggtgttcgct gtatcctggc tccgtaatcg tttctttagt aatctttgtc gcctcctctt
    13141 ctgatacacc ttgacgactc atcacatctt ggacattttg ttcgaaaact tgttgttggg
    13201 atgatacaga ccggtaagct gagaccatca ctaatggaaa tccagctgct tcagcagcct
    13261 tggcaaatgc ttcatattct ggagcaatgc gtttgtcgat caagtatccg ttacttaatg
    13321 atgccaattg agtagactca tcaatttctt tttctaattt gtgatctgga ccaaccaaaa
    13381 ctagcttcca atcgtctgtt ttaacatctg gcaattgttt ggacgtacga tcttttgttt
    13441 ctttgtcctt taccttgctg ctggttgttt gactgttctt ttctttacta gcagttgttt
    13501 tggtgcttgt tcgttcgact gcttgattgc cggcttgaac atgcgaatca tcatcgctaa
    13561 aaataacata gcccattgct gcgatcataa tcacaactgc tccaaatcct aaaaatttat
    13621 tcacttgaaa aatcctttcg ttgttcttca cgttccccat tcgcctcatg aacgtaagtt
    13681 tcttccagat tttcattcac ccaatcgaga agttcgattt tttctccttc gatctgtttt
    13741 tgaacatctg ctggcagacg aaaattcaaa atatcatcat agccccattc atcatattga
    13801 atacttactt tcaagtcaag gtatctacca gcctgctgat tatttttcaa agggatcagc
    13861 tcgacttttg ctgctttgct gctaagccat ttttgcgcga tgcgtgtttt gatttgcttg
    13921 tactctgcaa cggcaacgtt tcgtttttcg ggaaaaataa tcgtttgacg caaaatcttt
    13981 tgcgttagca tccattcata atcagtgaaa agatttttta ctttctgcat cgcttcagat
    14041 ggcagatttt tctcgccatc tttccatttt tgccattgtt ctggactgat cagcaagtat
    14101 tcatctaaaa aatttttttc agtttcaaac tgttctaata atacactcat aataagatca
    14161 atatatactt gatgcacgtt tatcccctcc ttttaactat tctacttaag ttttgatcaa
    14221 aaagcacctc ttaaatcgct gctttcattt tttttaatgt ttcaagtcct ctcctcttta
    14281 ttcttcgtga tttttgttat aataatagac agacaagaaa ctcaatccaa ctatgaagga
    14341 gcgttttcag atgaaaaaat atcaatgggg aatcgttggt cttggtacca tcgcacatga
    14401 gtttgccgaa agcttcaatc aagagacgag cgaactaaca gcagttgctt ccagaacttc
    14461 agaaaaagcg gaaaacttcg ctcaccgtta caatattcca aaagcttacg gaagctatca
    14521 agaaatgtta gacgatgctg aaatcgacat cgtgtacatt gctgtaccaa atagacagca
    14581 tatcgaccat atcttggcag cattggaagc aggcaaacac gttctatgtg aaaaagccat
    14641 cacgatgaat aaaaaagaac tggctgacgc tatgcgctta gcagaagaaa agaatttgat
    14701 cttagcagaa gcgatgacaa tcttcaacat gccactttat cagcagttac gctcaataat
    14761 ggatacagga aaactggggg ctttaaaaat gatccaagca cctttcggca gttacaaaga
    14821 accagaccct aaaaaccggt tcttcaatcc agaattagct ggaggagctc tgttggatat
    14881 cggtacgtat gctgtatctt tcgctcgttt ctttttgagc tctcaacctg aagtagttgc
    14941 ctctacaatg gttccttttg aaacaggcgt ggacgaacaa tccgtcacta tcttgcgtaa
    15001 caaagaaaat gaacttgctg ctgtcagctt gacttttcag gcaaaaatgc caaaagtcgg
    15061 tatcgttgcc tttgagaacg gttatgtgac gattgctgat tacccgcgtg ctgatcgtgc
    15121 ggagatctta tttacagatg gtacaaagga attcatcgaa agcgggaata catctgaagc
    15181 aatgaattac gaaataaaga atatggtaca catgattgaa ggtgacttgc ccaatcgctc
    15241 tctcttcttg acaaaagatg tcatcgaaat cttggatcaa atgcaagttc tatggaaaaa
    15301 tatgtaattt taaaaggttg tgaaaaagct gttctgcatc aagtaataag aacagccaaa
    15361 caaaaatagc tcctcctatt tttcgtttgg ctggacttat taccgcagag gaaagctttt
    15421 gaacaccgtt taagaaagag gttgtgagcc taccgttcag ctccgagtca caaggagcaa
    15481 tttcaaaaaa cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttgaca
    15541 ggagaacacc gtttaaagaa gaggttgtga aatcagcttt ttgacctgaa tattagctga
    15601 attcacaacc tctatttttg gattttttgt tgggagaatt ctgccttgat ttcaataaaa
    15661 cttttaaaag actgcaaaaa ctggaacaat tctgctcgat cctcgaattc agggcgacta
    15721 gtcggcagag gcatttgccg atacaataca taaacttctt caatacgtgt taaaatttgt
    15781 ctgccatcat ttgactctga aaatgtttct gcagtataaa tcaataaacc atagatatgt
    15841 tttccataat aagctggttg ctggattctc tctagatttt ccagcatgtc tttaatcaca
    15901 ttggcctgtg ctcttctcat agagaagtaa gtttcgtagt atagcggctg tctgagccag
    15961 tagttttctt gatgttctct ggcatcttct tggctttcgc gaatgaatgt cagtaaatgt
    16021 tcgcatttga tctgcacatc ttctttattt tctgataaaa gaaattctgc catttgtctc
    16081 aaaatatttc gaaattcttt ttcgatctgt atttggtttt ccttcagctg cttcgtacga
    16141 tctggcatgt aaacatttgc aagcaaagca aatactaatc caatcgccat taatcccgct
    16201 tcattgccga tcagctgcca agacatgttt tcctccacta aataatgagt gaccaaaacc
    16261 gaatttacta ctatcccttc ggttaatttg aagcgagagg caagcgggat gaacaggaat
    16321 aaaaaaagac tgaagccaaa aatagtatac ccaacagcaa aaaaactgaa cagtgctgtt
    16381 gccgtagcta atataaaggc tgcgattcga ttcatgcccg tacgcaatgt agagcgcttg
    16441 gtatttccta cacttaataa tgcaatgatc cctgcagctg gccaatacaa cagcgataag
    16501 ctacccgctg tgaccatcga aaagaagaca ctgatcactg ttttgactgt tcgcattcct
    16561 atacgcattt acttccccct tttttatttt aattatactt gaataatgaa aaactagcta
    16621 tcagacaaaa gtttaggtat gatagtaaaa agaccaaaaa ggagaatctc tatgcaattt
    16681 ggccgttttc gactaggtat gcgtacgatc aaaagtgcct tagctgtttt tttatgtatc
    16741 ttgttttttc atttgactca acgaggaatc ccgatgattg ctgcattatc tgctgttttt
    16801 tctttgcgtc aggacttgac tacaaccgtt tcttttggaa agtctaggat catcggcaat
    16861 acattaggtg gtacattagc tatcatttat ttttttgtca aaagctattt tcacaatgat
    16921 tttttggtag aattgatctt gcttcctatt ctagttatta ttgtgatcgt cgtgtcagat
    16981 ggtattaaca ataattccgg tatcatttcc gcaatagcta cgttgttgct gattgcgttg
    17041 agcatccctc aaggcgaatc cgctttgtat gctatccaac gtgtactaga tacttttata
    17101 gggacattca ttgcaatcgg tatcaatttc tttcttcgtc ctcctgaaac agaaaagaag
    17161 gaagaactat cagaagattt ggtcgaactc caaaagaaag aacgattgct aagaacaaat
    17221 ttacaagaga tagaagctaa gatccaaaaa caaaagaaaa atagcgagga ctaattttct
    17281 tttgcaataa aataaaaaaa tggagagaag aactttaaaa agtcttcctc catttttgat
    17341 tgaacggtga agtgtactac tttattcttc cttcatcgag ttttgttctg cctcttttgg
    17401 cgcttcatac atatttactt ggctagtagt cccacgtgtc gacaaattct ctacgatttc
    17461 cttcaagtca agtcctgttg tcgcttttag tgtttcttga gtagaagaaa gcaaatttgt
    17521 ggcataattt gtcactcggt tcgctccact ggtttctcct gaactgcttc ctgtatcgac
    17581 aacagagatt ttttcgatat ttcctagcgg ctgtgctgct tcgcgcatca attgcggtag
    17641 catatcgata accatactca agacagctgc ttcgccatat tccttgaagg cattggcgat
    17701 cttttgtttt gcttcggctt ctgcttttcc ttttgctagt gctgcttcgg cttctgcttg
    17761 tccagctaaa cgtgtcttat tggcttccgc ttctgccagt gcttccacac ggaatcgttc
    17821 tgcttcggct tcagtcactt ctttgacttt ttgagcttgt gcttcttgtt ctttagcgta
    17881 ccgatcggca tctgcttttt tcttcacttc cgaatcatat tgcttttcac gacgtgtgat
    17941 ttctttttct tccagttcga tttgtttttg acgttctacg attttaatct gcatttcctg
    18001 ttcgattact tgttgttgtg ctcgggcact ttctaaattg taggcttggt ctgcttttgc
    18061 tttagcaaca tcttgttctt gtttgtaggt tgctaatttc agttcttttt cttttaatga
    18121 ttctgcgatc tctgtttgtc gctgtaattc agctgcttgt gattcttttt ctgcttgagc
    18181 ttttttgata cgcgtttctt ttagagcttc cgcttctgct atatctgcat ctcttttgac
    18241 ttgggcgatt cttggtttcc ctaaagagtc aagataaccg tttttgtctc tgacctcttt
    18301 gatagtgaaa gaaacgatga tcaaccccat ttttgcaagg tctacagaag cgacttcttg
    18361 tacgctttga ctgaacttat cgcgattttg atagatttct tctacagtca tagaaccaag
    18421 aatcgagcgc aagtgtcctt ctaatacttc tcttgcttca ttttccagtt cttctcttgt
    18481 cttgcctaaa aactgttctg ctgctgtagc aatctcttct acagatgaac cgattttgat
    18541 gatcgaagta ccatcacaca tcaccggtac gccttgttcc gtatacactt caggggtgga
    18601 gacgtccaat ttactcgata atagactgat ccgattcgaa cgttgaaaaa ctggcaagac
    18661 gaatgcgcca cctccacgca caattttgat tttgttattg ctttcatcaa tgtgcacatt
    18721 tttgcttcct aaataacttc cactgatgat caacgcttca tccggttttg ctgtctggta
    18781 cttcgctaca aagacgatca gcaacatcag taaaatcaaa gctgcgattg cgatcgcgat
    18841 aaaaacaact ggtatttcca tttaacacac gctcctttaa gcttttatca tgctttcata
    18901 aggcatgaca taacagattc tttccttgat ctcaatgatc aatactttcg ttccccgctc
    18961 agctgtctgt tcttgggggc tgtaaaaaca agctggacga ctaatggaac cggtaacact
    19021 tttcaactga atttctccca tacctcgtac agggatcggt gtgatcacaa cagctacttg
    19081 tccttccaga gttttttcag aagacgacat cgttgattcg gcatgtttca tcggcatcaa
    19141 tatatagaaa ttaagcaaaa ataccaacac tatcgatatg cctccactag caataaataa
    19201 aaataaagat gattgatctg ttaaacgctc acctagaaaa ccaaataagc ttgtgaaagt
    19261 taaccaaggg ataataagca tcggatcaag cgggccatca aaatcgaata catctccaaa
    19321 aataatcaat aggactgcca atcctgcaca aatcagcaat gtataccaat aaatcgtctc
    19381 aagtgcgatt ccccctatca tatacacgcc tccttccatt tctacgtcta tcataccaat
    19441 gtttgaaaat tctgtatagc ttcttttacc gactcagtgg tgttttttat aggaaggttg
    19501 tgtttatcgt tgacaatttg ttaaattttt gttttcatgt taaaattttc acaataaatt
    19561 ctttcgaggt agcctatgtt tccttttttt aagaaaaaac cattaaagct ccagaacacg
    19621 atcatccttg tcgtttgttt ctccacattc gtttctttga ttgtttctgc catattgatc
    19681 aggaatttta ttctttcgat gaaccgatct agtgtgtcag ataaaatctc tagcattgct
    19741 aaaatcgttg ccaatgataa actcatccaa aaaaagctgc agactggtga cccgacacat
    19801 gcgattcaag gaataacaaa tgaaatcatg attgcatcga atttagattt tatcgttgtc
    19861 atggaccctg aaggcattcg atattctcac gcagacccaa gttacatcgg tcttcctttc
    19921 tcaagtcatg aagatgtgaa aaaagtgatt ggaggacaag aatttttctc tgaaaaagaa
    19981 ggaatgttag ggttcggctt ccgctatttc gtccctattt attatgatca agagattatt
    20041 ggtgcagttt gtgttggctt aacaaacaac acgattgaca atcaagtcaa agatggacaa
    20101 aaaatgattg ttttttcatt gattattgga cttagcgtag gcatcatagg cgccgttttt
    20161 cttgcccaaa aaatgaaaaa agtactgctt ggacttgaac cacaagaaat agcagaacag
    20221 ttaagtgaaa aaacgattat cgaaaatgaa gtagatgaag gaatcttagc catctcttct
    20281 gataaaacta tcctcttgat caatacacct gcaaaaaaca ttttctacca aacagagcag
    20341 ctattggatt tcgaagtagg aaaaaaatca gtgataatct atatgacgtt ttgtttaaag
    20401 agacgattga gcatcaaacg accgttcgga ctcaatccat gtatttaaat gggatagaaa
    20461 ctatttctag cgttacacct ctttttagca atgaccgttt tttaggagca gtcgcaactt
    20521 tacgaaatcg atcagaagta atgaaattaa tggaggagct tggggggacg aaacaatata
    20581 taaactccat gagagctcaa acccatgaat tcatgaataa acttcatgtc atttctggtt
    20641 tgattgattt gaagaagtat gaagaagtca cccattttat ccagcagcta aatcaaaatt
    20701 ataaaaaaga gattggccaa gtctcaagtc tgatcaaagt acctgcaatt gccggttttt
    20761 tattaggcaa aataaacgaa gccaaagaac aatctgttga aatgctgtta gaaagcgatt
    20821 cttttatccc taaaatggag atggatgact ccatccattc acttttgcaa gtgttaggga
    20881 acttacttga taatgcaaaa gaagccgtgc tacaaaaaca tgaaagaaac ggacaggtcc
    20941 ggattcattt aaactatgac acagaagctg aagtattcat cgtgaccgtc tgcgatgacg
    21001 gtgtcgggat atcagaagaa atctcagaaa aaatatttac gctaggtttt tcgacgaagg
    21061 gaatcaatcg tgggtttgga ttgaatctca tccattcaat cgtcaaacgc cacggtggat
    21121 ttttagaatt ttccaaacaa acaaatggcg gtacaatcgt ctatctagaa ttaccaaaaa
    21181 aggaagatca aaatgatgac aaatgtcctg ataatcgaag atgatccaat ggttgcagaa
    21241 ttgaatcgta cttttgtgga aagcatccct aatatgaacg taatcgaaag tttcagaaat
    21301 gtagaagaag gaaaaaaata tttcagacaa aaaaacgcag atctgctgct gcttgatgta
    21361 tacatgcctg gcgaaagtgg tatccatttt ttatcttggc ttagacagca aggaaatgat
    21421 atcccagtga ttttgatcac tgctgcagat gatatcgaaa ccataaagaa tgtgatccgc
    21481 tacggtgcct tagattattt gatcaaaccg ttcactttgc aacgttttca gctggcgatc
    21541 gaaaagtatc ttgctttctc tcagacaatc caaacgactg aaaaagccga tcagaaattg
    21601 atcgatcaag tattcaacca caccactccc attcacgaaa taccatcatt catcgatttg
    21661 cctaaaggtc tgtcaaaact gactttaaaa aaaataagtg catttattct aaaagaagat
    21721 actatttttt caacaaaaga actggctcaa aaaagctcac tgtcacgtat atccgtcaag
    21781 aaatatttga attttttagt agaacaagat atattgaacg aaagaatcaa atatttggaa
    21841 atcggccggc cgctaacctg ttatgaattg acaaagaatg ggcggaaaaa gctcacagat
    21901 tactgttgag tcatcgaatt atcccataca aaatagtcca agtatacaga agtaacaact
    21961 gtttacttgg actattttta aacattttat tgacgaatat ccatgttttc ttatcttaat
    22021 tgacgggctt taggaagaga tacctcattt ttcgtttttc cagtttctat tatttcacga
    22081 aagttctcga aacttgtcga aatcatattt gataatgcct catctgtatt tgaacctaca
    22141 tgcggggtta caagaactct agggtacatt tctactaatt gctggatagc agggtctgga
    22201 atcgtctccc atggcttgaa ggatcggaaa aaaacctctg tttcatttgc aaaaacatcg
    22261 gttgcaaaac cagctaaatg attgcttttc aaagctctta aaatagcttc attatcttga
    22321 agctctccac gggctgtatt aatcaagatg ctaccttttt tcatttgagc taaaaatcct
    22381 tcattgatca tttgatcgtt ttcacctggg atatgaggta catgaatact gacaatatcg
    22441 cttttggcta ataactcttc aagcgagtgg aacgtcaata cttttttagc agcttctgtc
    22501 tgatgaatat cgtagccgat cactttggct cctagtccct taaacaaaac agcttccgtc
    22561 aaccctatcc tgcctgttcc tatgatccct actgtgcaat ttctgatttc acgactaaac
    22621 atttgctcat ccactcgaaa atctttgaaa gatgttcgga tcgtcgtata cgcagtattt
    22681 ctcaaaagca tcatggcaaa agtcaaagat aactctgcta tcgcatttgg cgaatacgat
    22741 ggtacacggg ctactgtcat accaaaatca gctgccgctt gtagatcgat atgattgact
    22801 cccacagtcc gtgtaaaaac ataacgaatc ccatattcct gcatttttgc aagattggtc
    22861 tcatctgcta tacaatttcc cctcaacaat acagcatcat ggtcctttgc tgacacgata
    22921 ttgtcatgtg tcaacagttc ttcataaaga ctgagatcat aatggtaaat attcaatttt
    22981 tcaaaaaaat ctatctcgtt cggacgaaca ccgtaacatg cgattctcat actttcttcc
    23041 tccatttctt atgaaaataa acctatgcca tgaatcattt gtaatacaac gatccataca
    23101 ggtgtcagta ccacagcaaa aatagttgac agtaaggatg cattggaggc taaaagtgcc
    23161 tccctatcaa aactgatagc ataggctgct gccactgttg cagctggtgt agccatcatg
    23221 ataacgattg ttgccagtgc ttcaaaattg actggtagaa tattcgttgc cgtcaaaact
    23281 gctagaatca cgatattcaa tgcaggtaca aataccactt tgactagact gtaataccat
    23341 gaagtttttt cagatgcagc ttttttgaag cttacttcac ctaatgttgc gccgattgct
    23401 agccacgcca atggtgaact taaaccagct aaataatcca tcggctgaaa tagccacggt
    23461 gcagtctggt caattcgcaa aaacgctact tggcttatct ctccttctgc acctgtaact
    23521 gacacttgtg gcagataccc ttggaacagc caaatgaaaa ggccggcaaa agtagcgata
    23581 atgattggat tgacgaacat cgctttgata tttttagctt ccatcttcaa gccactcatt
    23641 tttatgtatc cataagaata caaaaagatt cggtagccaa tattgaaaat tgaggaatac
    23701 atcacgccga caggaccata aatcgcactg acgataggcg ttccgaaaaa ggtcgtagaa
    23761 ccaaagatcg tcaggacacg caacgttgtt tgcttatccc ctttatagct taagaaaaaa
    23821 ggttttgaaa ctagaataag aataatataa ataactaatc cccaaatcaa gacattgatt
    23881 ccttgcatca gtaattctgt attgatatct tgcatgaaag ctcgaaatgc cagtgctggc
    23941 aaagccactg ttaagacgac tttcgataga atttttccaa cagattcaga aaaaatcccc
    24001 ttttttctac aaacaaaccc taataatata ataaaaactg ttgaagtgat tgcactgaca
    24061 atcgacatat ctgtcaaagt cgatcgaaaa atgtcaaata agttcatctt tctcctccta
    24121 attatgttca tttattcaca ataaaaaaag cttttatttt gctaatacgt attaacattt
    24181 ttaattttat ctttacattg ttacttattg aacaatagga aattaaagaa acttttgaaa
    24241 cttatgtaaa gtgatttt
//
LOCUS       DBBGSP010000046        23695 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000046 DBBGSP010000000
VERSION     DBBGSP010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.046"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(531..2027)
                     /gene="lysS"
                     /locus_tag="ACIZE9_002109"
     CDS             complement(531..2027)
                     /gene="lysS"
                     /locus_tag="ACIZE9_002109"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGC6093955.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2138..3142)
                     /gene="dusB"
                     /locus_tag="ACIZE9_002110"
     CDS             complement(2138..3142)
                     /gene="dusB"
                     /locus_tag="ACIZE9_002110"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGC6093956.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3143..4030)
                     /gene="hslO"
                     /locus_tag="ACIZE9_002111"
     CDS             complement(3143..4030)
                     /gene="hslO"
                     /locus_tag="ACIZE9_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGC6093957.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4247..6358)
                     /gene="ftsH"
                     /locus_tag="ACIZE9_002112"
     CDS             complement(4247..6358)
                     /gene="ftsH"
                     /locus_tag="ACIZE9_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGC6093958.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6448..6993)
                     /gene="hpt"
                     /locus_tag="ACIZE9_002113"
     CDS             complement(6448..6993)
                     /gene="hpt"
                     /locus_tag="ACIZE9_002113"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGC6093959.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6993..8438)
                     /gene="tilS"
                     /locus_tag="ACIZE9_002114"
     CDS             complement(6993..8438)
                     /gene="tilS"
                     /locus_tag="ACIZE9_002114"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGC6093960.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8558..9028)
                     /locus_tag="ACIZE9_002115"
     CDS             complement(8558..9028)
                     /locus_tag="ACIZE9_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HGC6093961.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9074..9499)
                     /locus_tag="ACIZE9_002116"
     CDS             complement(9074..9499)
                     /locus_tag="ACIZE9_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGC6093962.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9566..9835)
                     /locus_tag="ACIZE9_002117"
     CDS             complement(9566..9835)
                     /locus_tag="ACIZE9_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGC6093963.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9846..11441)
                     /locus_tag="ACIZE9_002118"
     CDS             complement(9846..11441)
                     /locus_tag="ACIZE9_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGC6093964.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11456..14977)
                     /gene="mfd"
                     /locus_tag="ACIZE9_002119"
     CDS             complement(11456..14977)
                     /gene="mfd"
                     /locus_tag="ACIZE9_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGC6093965.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14994..15554)
                     /gene="pth"
                     /locus_tag="ACIZE9_002120"
     CDS             complement(14994..15554)
                     /gene="pth"
                     /locus_tag="ACIZE9_002120"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGC6093966.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15907..16881
                     /locus_tag="ACIZE9_002121"
     CDS             15907..16881
                     /locus_tag="ACIZE9_002121"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGC6093967.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17051..18451
                     /locus_tag="ACIZE9_002122"
     CDS             17051..18451
                     /locus_tag="ACIZE9_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HGC6093968.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18529..19251)
                     /locus_tag="ACIZE9_002123"
     CDS             complement(18529..19251)
                     /locus_tag="ACIZE9_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6093969.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19330..19836)
                     /locus_tag="ACIZE9_002124"
     CDS             complement(19330..19836)
                     /locus_tag="ACIZE9_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGC6093970.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19959..21758
                     /locus_tag="ACIZE9_002125"
     CDS             19959..21758
                     /locus_tag="ACIZE9_002125"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HGC6093971.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            22252..23640
                     /gene="ltrA"
                     /locus_tag="ACIZE9_002126"
     CDS             22252..23640
                     /gene="ltrA"
                     /locus_tag="ACIZE9_002126"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGC6093972.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
BASE COUNT         6712 a         5100 c         4363 g         7520 t
ORIGIN      
        1 agagtgtttc ccgattcatt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagcgattgt caactctttt ttaaaagttt ttttcgattt cgtttttcga aatctttcgg
      121 caactcattt atcataactt atcgtttgtt atttgtcaag aacttttttg aagttttttt
      181 cgatagaatc aagcttcgca agtggttctt ttttaacgac tcagttatct tatcatgtcg
      241 ttagtaacat gtcaataact tttttgttat gtttttgaat aaatattttc ttctgtcttt
      301 tggacaagta ataatatacc aactaaattt agcttggtca acgaattttt tgtatttttt
      361 caagtttttt tcaataaacg attattcata acttttcttt ctttatcgtt cgttttcgtc
      421 ttctttaatg tctagaatag tcggcattag cttttgaact ttcgttatta tttattcctt
      481 tctacacagc aaaagctgcc taaggaattc cttagacagc ttttattcga ttatctcatt
      541 gttgggaata gcaaaacatc ccgaattgat tgtgcatcag ttagcaacat tactaatctg
      601 tcgatcccga tgcctagacc accagttggc ggcataccgt attctaaggc ttccaagaag
      661 tcttcgtcta caccgtgagc ttcgtcattt cctagttcac gttctttttc ttgcgcttcg
      721 aatctttctc tttgatcaat tggatcgttc agttctgtaa aggcattagc aaattcgcgc
      781 cccactatga atagttcgaa tcgatctgtg aatcgaggat cttctggatt tttcttcgct
      841 aaaggcgaaa cttcgactgg atgtccgtat acaaacgtcg gttgtgtcaa tgtttcttca
      901 acaaatgttt caaagaattc attgataaca tgtccgacac ccatagcttc ggttacttct
      961 acattgtgtt tttcggctaa agctaatgct tcttccaatg tcatttcttg ccagaagtct
     1021 acaccagttt gttctttgat tgcatctacc atatggatgc gtttaaagtc actttctaag
     1081 tcgacagctt gtccatcata tgtgattttt gctgttccta gtactttttc agctgcgtta
     1141 cggataatac cttctgtcag attcattaca tcattgaaat cagtatatgc tgtgtatgct
     1201 tctaacatcg taaattctgg attatgtgta gtatcaattc cttcattacg gaaaacgcgg
     1261 ccgatttcat aaactttttc cattccgcca acaattagtc gttttaaatg aagttctagc
     1321 gcaatacgca aatataaatc aatgtccagt gcattatgat gcgtgataaa tgggcgtgcg
     1381 gcagctccac ctgcctcatt gtgcaatact ggtgtttcta cttcaatata gccattgcca
     1441 tctaaatagc gacggatttc gctgataatt tggcttcgtt tcataaatcg gtcaaagctt
     1501 tcgcgattac tgattaaatc caagtagcgt tgtctgtagc gttgttcaat attcgttaag
     1561 ccatggtatt tatctggcag tggacgaagt gcttttgaca aaatcgtgat ttctgaagct
     1621 ttgatagaaa cttcgcctgt gtctgttttc atgatttgtc cagttacacc aaagaaatct
     1681 ccaaggtctg catgtttgaa tacttcatag gcctcatcac ctacttggtc ttttcttaca
     1741 taaatttgaa tttggccttc acgatcttgt agatgcgcaa atccagcttt cccttttcct
     1801 cggcgagtca tcatacgacc agctacacta gcggtcaatc ccatttctgc tagttcttct
     1861 tttgttcttg gatcaaatag ttcatgcaat tcttctgagt tgtgcgtgcg ttcaaatcgt
     1921 tttccaaatg gatcgattcc atcttcacgc aattgttcca ttttttgacg acgtacaagc
     1981 atttgatcat ttaaatcttc tacttgatgt tgttgttcct gtgtcacaaa agttcctcca
     2041 ttctcatgtt aatctctttc ctataatgcc aatgaaacac aaaaaaagca agccgaactt
     2101 ggaatttcgg cttgaaaatt cacgaaaaac ttagaaatca caacgtttgt ttcaatagta
     2161 ctttttccgc tttttctaca aattgatcca gcaggtcatt gatttcttgc tgtttttctg
     2221 tctgattgat tgctactttc actttcgctg ctcgaggaat cccttttaaa taataagccg
     2281 catgtgttct gaattctcta caagctactt tttctccttt gagatctgct aagcgttgta
     2341 aatgaagttt agctgtagca attttttcgg ctggtgttgg ttcaggaatc agttcccctg
     2401 tttcgagata atgctgtgtg cggtgaatca tccatggatt gcccagcgct gcacgaccaa
     2461 tcatcacacc gtctgcaccg acatagtcaa gcatccattt tgcatcttct ggcgttttga
     2521 catccccgtt ccccataaat ggaatcgtca aatgtttttt cacttctttc aatacttccc
     2581 agtccgcttt tccttcatac atctgaaccc gtgtacgtcc atgcatagcg atggcacttg
     2641 ctccagctga ttgtgctgct aatgcatttt ctacagcaaa gacgtgctct tcatcccaac
     2701 caatacgcat cttgattgtt actgggatat ttactgctga agaaacagct tggaccattt
     2761 cgtatacttt ctcaggatct aaaagccatt ttgctcctgc ttctgctttg attactttat
     2821 ttactggaca gcccatattg atatctatta tatcggcagc tgtgttttct tcgacaaatt
     2881 gagcagcttc aactagacta tctttatttc cgccaaatat ctgtaaactt aatggatgtt
     2941 ctgtttcttc aatgtggagc atctctaaag tttttttgtt tctgaaatga ataccttggt
     3001 cactgatcat ttcacatacg actaagcccg caccaaattc tttgacagtg actcgaaatg
     3061 ctgaatttgt tattccagcc atcggtgcaa caacgacacg attagggatt tccacattgc
     3121 caattttcca tgtgtgttcc acttaaatcc ctcctaaggc ttctttcttc aatccatcta
     3181 attcttcttc gctatacttg tatttgttat tacagaaaga acaaaccgct tctgcaccgt
     3241 gatcttcgtc tatcattgct tggatttctt ctgcacctaa cgcgataatt gcttctgcaa
     3301 atttttcttt tgaacagtca catttgaatt gaacaggcat tttttccaaa atgttcaatt
     3361 cttctgtacc aagcaatcct ttcaatattt cttctggtgt ctgtccttca tctaagaggg
     3421 tagagattct tggtgtcgtt tttaattgtt cttcgatctt gctgattgtt tcttcatcgg
     3481 cacctggcat gatttggatc atgaatcctc ccgccgtctt gatgctgtcg tcagtattga
     3541 ccaatacact cagtccaaca gctgaaggga tttgttctga gatagcaaga tagtaagtaa
     3601 aatcttcagc gatttctcca gaaacaatcg gcgtttgccc agaaaaaggt tcttttaatc
     3661 ctaagtcttt tgtgacagta aacattcctt gtgttccaac tgctccccgc acatcgattt
     3721 taccttcact atttagagga agactgagat gcggattttt gatgtaacct ttcacatctc
     3781 cctttccatt tgcatctact acaattcctg ttgctggacc atcgccttgg attcgaacag
     3841 ttagtttgtc ttctcctttg agcgtcgcac caagtagcag actaccgacc aatgtccgtc
     3901 ccaaagcagc tgaggaggtg tgccaagtat catgacgtct ttgtgcctcc gctacggtat
     3961 ttgttgcttg aacggcgtat gctcggacga atccgtcgtg agcaagtgcc ttaaccaaat
     4021 aatctttcat ttgttatgta ctcctttttc cgtttttaaa ctcatagtga atcatactag
     4081 caactactgc ttttttcaac tttggaatgc ttcttttaaa aataattcag aatcatctag
     4141 aaaacaggac atcaccctat ttacaactta aataaagaaa tctcccgaaa accggttttt
     4201 gttccggttt tcgggagtca tatcagatca attgacctat atttttttat ttgtattgat
     4261 cgtctgaatg attatcttct gattgttgag aatctgaatc atgttctgct ttattttcct
     4321 cattcagttc atgttttgct tcttcaaaat cacgtttttc ttccgcttgt ttttcagcgt
     4381 ctttttcttc caaagcacgt tttgcttctt caaaagtttt cgcttctttt tcgcttggat
     4441 aatcatttga ctcagtacct tcaggcatca caccgtgttc aaacaatgac ttgattgctt
     4501 tggcatccaa tgtttcgaat tccaaaagtt tttcagcaat cagtttatgc tgtgcacgat
     4561 gagcttcgat gatttctcga gctttatcat gagcttccat caagattttt cgtacttctt
     4621 gatcaatctc gaaagcgact tgttccgagt aagcttttgt ttgaccatag tcgcggccaa
     4681 caaacacttg atggtttcct tcatattgaa caggacctaa acgatcactc attccatatt
     4741 ctgttaccat gcttcgtgct agagctgtcg cttgctcaaa gtcattggaa gcaccagttg
     4801 attggacatt gaagatgatt tcttcagctg tacgtccacc aagtaagcct acgatttgtt
     4861 caaacatatc ttctttcgtc atcaagaact gatcttcttt tggtaaagcg atcatatatc
     4921 cgccggcgcg tccgcgaggg atgatcgtta ctttgtggac gacccgagcg cgactcaata
     4981 ctaatccgac aatcgtatga ccagcttcgt gataagcaac catttcgcgt tcttttttgc
     5041 tgattacgcg atctttttta gctggacctg caatcacgcg atcttccgct tcatcgatat
     5101 cagaagcatc gattttcttt ttatttcttc tagcagctac taacgctgct tcattcaaga
     5161 cattttctaa atctgctccg gcaaaacctg gtgtctgttg agccacaact ttcaagtcaa
     5221 cgtcatctgc catcggttta ttccgtgcat ggactcgcaa gattgcttca cgacctttta
     5281 catctggacg tccaactaaa atctggcggt caaaacggcc tggacgtagt aacgctgggt
     5341 ctagtacatc agaacggttg gttgcagcaa tgacgattac tccttcattt ccgtcgaagc
     5401 catccatttc tacaagcaat tggttcaatg tttgttcgcg ttcatcatgt ccgccgccca
     5461 taccggcacc acgttgacga cctaccgcat caatttcatc aatgaaaatg atagctggtg
     5521 cgtttttctt cgctgtttca aacaaatcac gaacacgact tgctccaaca ccgacaaaca
     5581 tttctacgaa atcagaaccc gagatcgagt aaaacggtac tccagcttct ccggcaacag
     5641 cttttgctaa taaggtttta cctgttcctg gaggtccttc taaaagtaca cctgccggga
     5701 tacgggcacc taattcaaca aatcggcgag gatctttcag aaattcaaca acttcaacta
     5761 gttcttgttt ttcttcttcc gcacccgcta catcagaaaa acgtacgcga ttagcttttt
     5821 tgtctgcttc tttggctttt gatttaccaa agttcatgac acggccgcca ccgccaccgc
     5881 cgccgccttg ttgtcccatc atcatgtaaa agaaaaagat gatgattacg attggcaaga
     5941 agctaagcaa tagggaaacc catataccgc tgcttgattc ttcttttact gttgtagcaa
     6001 ctttgttttc ttttgccagt tctgttactt ggctcaatgt tgtatcattt ggcaaaatga
     6061 ttgttgtgaa atgggtagta gtcgtatctg ttgaacctaa gatagctaac ccaccgctgt
     6121 tagcgacggt ctgctgttct ttgtattcac cagtgatctt atatacacca tttgcaggct
     6181 gcacttcaaa ttctttgatc ttgcctgctt gtagttgttc tgtgaatttt gagtactcga
     6241 tatctgacga tcgctggccg ttattaccaa aaatgaaata aacgaccatt accatcgcta
     6301 agattacgag gacataatac aaggcatttt tcatcatgcc gttgttcttt ttgttcatag
     6361 ttgccctccc taagcgtcaa tttaatttaa cagtttttta tcaatcctga ccattctatt
     6421 gtaccataat ttaattgaga tacagcatta atttgattga taaacactag gtttcaatac
     6481 accgatgtac ggaaggttac gatatgcttc tgcataatcc aagccataac cgaccacaaa
     6541 ttcatttggt acgttgaagc caacataatc tgcttcgata tttactactc ttccttcagg
     6601 tttgtcaagt agtgtaacaa ttttgactga ttttgctttg cggtatttga aaagatccac
     6661 taaataagca agtgttcttc cgctgtcaat gatatcttca acgatcaaca gatcgcgacc
     6721 ttctacattc gtatctaagt ctttgacgat ttttacttcc cctgacgaga ctgttgcatt
     6781 cccgtagctt gaaacatcca tgaaatccaa ttccaaatac gtatcgatag aacgaacgat
     6841 atctgccatg aatggtaccg ctccttttaa gacacctact actaggggat tggtgttttg
     6901 gtaaatttct gttaactctt tgcctagttc tttgcaacga acttgtatct cttcttgtga
     6961 gatcaaaatt ctctcaatat ccttttccaa catcaggttc tccttccaat tgcttctttt
     7021 tgatatttgt aaagaagtat gtagtgtatt ttatcagttt cttcacgaat actcaaatat
     7081 gaaaaggcaa aaggtatcaa gctatatata tttcttttgg catctgtaat gatccaagca
     7141 tgctgccttt gtgaattagg tactttctga tcgataaaat atctagatac tttttttgtg
     7201 agattctctg ttaatttaat gcggtctcct gcttttcttt tttcgacata cagttgcaca
     7261 tcagcaggaa tccaaatgtc atgagaaaat agagaccatg aatctgttgc tttgatgtcc
     7321 cctgcatttt caggtttgac cagaccaatc cattctgttt cattcaaata tattccttgt
     7381 tctggaatca gcaacaagcg ctggtcttct gtctggctag ttgcttgttt ttctttttta
     7441 gagagtacaa caaaatgata ctctcttttc agtatccaat tattgccaat actgagttgc
     7501 cattggcttt ttttctgttg ccactggtct aaaatcgact ccatttgttg ttctttcaaa
     7561 ataattcctg tttttgagaa tgctttgtcg aaaaaggagt aaaaaaaata gtatcgttca
     7621 gcatctgtca tttcttcaat catttctgca gaaaatcgaa attgttcctc ccactgttcg
     7681 acttcctttt cgatcaactg tcccatatat ttttgaatga cttggtctgc ccattggatc
     7741 tgttgcgaaa attgctggaa atgtctcaac gcctgtgtat tttcttgttt caattgagga
     7801 actaccaaat gacgaagccg atttctctgg atatctaaca attggtttgt ctgatcctca
     7861 aagtaaacaa gctgcgattc cgctgcataa gtatataggt cttctttgct aaaactcagc
     7921 aacggacgaa tcagtctgcc cgtagcaaat ggttgtactt ctttgattcc agaaaaagta
     7981 tttaactgtc ccccacgaac gattttcatt aacaccgtct cgatttgatc atctccgtga
     8041 tgagcagtca tcaacgtgtc atattgtcct tcttccatca cgcgagtgaa ttcttgataa
     8101 cgaaagttac gagcttctgt ttctatggcg gatttggctg gatcttccca aatacttaca
     8161 tataaaggga gattcttctc ttcacaatat gagcgaagat aggcagcttc ttctgctgat
     8221 tcttctctta attggtgatt gatgtggacg atacctaaag aaaaaccgat ttggcgttgc
     8281 acttgtaaaa gtaaatggag caaaaccatc gaatcaacac cacctgatac cgctgctaaa
     8341 attctcgatc cttgttgcca gaatccttgt tcattcccgt gccgaataaa tgactgctgt
     8401 aatagcggtg cttttttccc gcctttttca acgttcatcc tttccacacc ctttcttcct
     8461 aaaaaaaaga gagcgggaaa acgtctaaaa cgacaattaa cctgccctct gttgatacta
     8521 tgacccaaat agtcgcacta tcattatttg cggcttttta gctgcgacgt ccgccacggc
     8581 caccgcgctt tccttctgtg tttcgcttca atgaagataa gcggtcatcg ctatctttca
     8641 aaaatgaact catcaatgaa tcgaagtctt ctttttgagc tgaaggttga ctgcgagaaa
     8701 aagatttttt ctgtgctgga cgatttcggt tgtcacgggg atctttttgt tgatattttt
     8761 taggacggct ttcttctcca gattcagcag gttgttcctg cgctttccgg atagatagtc
     8821 cgatttttcc atcatcattt actgaaataa ctttaactgt tacttcatct cctacactta
     8881 aaacatcatg gatgtctttt acatagccat ttgacacttc gctaatatga actagacccg
     8941 tttttccagc acctagatca ataaacgcac caaaatttgt gattcctgat acttttcctt
     9001 gcagttttgc tcctacctcg attgacataa aaaaaatgtt cctcctaatt atttcccttt
     9061 tttatattcc tgcttatttt gcagttgtag aactagttga ttgatctgtt tcatttgtcg
     9121 agctgtctgt atttgattct aatataggat aaactttttc accgtctttt gagtaaaaga
     9181 atttgcttct ggcaagttta gctacatact catcatcttt cagcaatgaa acatcttggt
     9241 gcagctgatc aacgtctgcg ttgacttctt tcatttcagt atttgcttcg actctcaatt
     9301 cgttcaattg atgcatcctt tgcatgtcat ggaaaatctg cacacctatt atcgcgaaaa
     9361 tgaccaaagc accaacaaaa attgcagcca gtctgcgtct tcgaaaaatc agttgacgtt
     9421 gttgttgctg aaattcagca tactttttct ttgcatattc cgtatctagc gcagcgattt
     9481 tattgctttt tttcgtcact tggattcgct ccaatctttt tgattgtctt tttcattata
     9541 ccaatatcgt gaaagcttgt ctaatctatt tctctagtgt ttctgtgcga ttttcagaaa
     9601 taatttcgta cattttttgt gcatcttctt ttttggttga ttcatgtaat tccgtaattt
     9661 tcacttccaa cgttttgttg ccaaactgga ctttcaaaat atcgcctact ttgacatcac
     9721 tggaagattt cgccaattta ccgttgattt gaattcttcc tttatcagct acttcttttg
     9781 ctactgatcg tcttttgatg attcgggaaa tttttaaaaa tttatctaat cgcatatctt
     9841 attcctcact ttttaatttt tttatttaat cgcaggattt tcttaccaaa aggcaacatt
     9901 agccattctc gtactgtaaa cagacgaaga cgaatcactg cataaatgaa cacagaagcc
     9961 ccgatcccaa ctcctatcac gctgacaaaa aaagcagtgg aacgatgagt tacaggacca
    10021 aatactatat tcaatacacc ataatacagc agcagtacta ctgtcataca aagaaggctg
    10081 aacatcaact tccgtccaaa atgccgttct ttccaaaaag catttagctc ttttgtttca
    10141 attcgaacaa aataccaaag cgtcacacct aatcctaaaa gggtagacag gcttgcacct
    10201 gctgttccta ataaaccggt cagaaaagaa gtagtcaatc cttttaccaa tagtccccat
    10261 cctgcgcctt ttaaagaagg gcgaaacgag ttcttgcttt gagcaatact ttgataagct
    10321 tggatgactg cagtgaaagc aatggaaaaa acaaataata caagcgctgc atttcccgca
    10381 taatctttaa acaacgcata attgatataa gggagcagca aggctaatcc caaagacgca
    10441 gctaatgcta aagcggtcgt caatctaaga tagattttgg ctgtctgtaa aaactgacga
    10501 tagatccggt tggtcaaatg acgagtcaac gcaggcagga atgtcgcact taatgcagtg
    10561 gcaatcacta aacctaattg tactaaaggc tgacctcgat catagacccc ttttgctatc
    10621 ttcgcaccgt attctgacag tccgtaaact tccaaagcat tttttacaaa gaaagagtcg
    10681 atcagctgga aaaagataag caatccacta taaatcgaaa ccagtccgcc ttctaccaga
    10741 aaacgccgga tcaagggctt tgacggctgt ttgaacaatg gaaaccgtcg gaagcttaac
    10801 gctcctccat gaatcttttg ttcatagtag tgaaggatcc catatgcgca taaaccgcca
    10861 aaaacagctc cactcattgc tgccgtccct gtttggtaca ccgtccatcc aagctttcta
    10921 aaagcaaacg cactacagac aatcacaaaa acacgaacga actgctcaac tacttgagaa
    10981 acagcagttg gttccatcaa gaatcttcct tggaaattcc ctcgataaaa agatagacca
    11041 ggcatcagca aaaaggtaaa ggaaactact tggatcagcg gtttcaattg tatgtctccc
    11101 atcatccaag caatccagct gctaaatgca aagacaaaca accacaaaaa gacacctgtc
    11161 caaaatacta agggataaag attttgcaaa gcttgctttc gctcgaaagg attctttctt
    11221 tctgcaacgt actttgatat gaactgcgga agaccggata aagctaaagt cattgctatc
    11281 ccataaattg gataaacttg ctgataaaca taaaaacctt cgtcgccgac taagttttgg
    11341 aggggaattc ggtaaagggc acttaatact tttgctatga aagaagcaat cgtcaataca
    11401 aatgctcctt gcatgacgcg ccgcatttct ttatgatcca aatcattgct ccttcctacg
    11461 ctgacagata tttttgctca cgcaacgctt tgacaaactt ttggatttcc tgaagccata
    11521 ctgcttcttc catttggttg gggatcgtca agcgtatcac catctgttct ttttcaacgc
    11581 ctagactggc ttttagtttt gtcgctgtca gtgcttcgaa taactgttcc acactatagc
    11641 gttttgttcc aactttactt agagtaaaga ctatatgcgc ctcctgtttc cttatcgttt
    11701 ctaggagcgc tcgatcgcca tccattttga tctgcccaat tgtcaagaga tgtgctactt
    11761 cttctggata ttctccaaaa cggtcgagca gatcatcttc tagttcatct agcatttctt
    11821 gcgaatcaag ttcacgaatt cgtttataga tctcgatttt ctgccgttga tctgccacgt
    11881 atgtttcagg tagatacgca tcgacaccga ggtcgatctc aacagtggtc ttctccactt
    11941 gactattctt tccttgttta cgagaaacag cttcgcttag catttgagaa tacatatcga
    12001 aaccgactgc atcaataaat ccatgctgct gagcacctaa gagattacct gcaccgcgaa
    12061 tggaaagatc ccgcatcgca atcttgaatc cagatcccag ttctgtaaaa tctttgattg
    12121 cctgaagacg tttttcactg acttcgttaa ggatcttctg ctgctcatac ataaagtaag
    12181 catatgcgac acggctgctt cttcctaccc gccctcgcaa ttggtataac gtggataatc
    12241 ccatataatc agcgttctca acgaacaacg tatttgcgtt cgggatatct actcctgttt
    12301 caatgatggt tgtagtgaca agaacatcat attgaccttc aataaattca aaaagcgtat
    12361 tttctaattg cgcctctgtc atttgcccat gagcataacc gatccgtgct tccggaacga
    12421 gttcttggat ttcttctact ttttgttcga tcgtttctac ccgattatat aaatagaata
    12481 cttgtccacc tcgtcccatt tctcgatgga ttgcttcgcg aatagcccca ggattttttt
    12541 ccataacata cgtttggatc ggataacgat tcgcaggcgg tgtttcgatt actgaaagat
    12601 cccgcacgcc taacatcgac atatgcaaag ttctcggaat cggtgttgca gtcagagtca
    12661 aaacatccac ttgtgcacgt aactgtttca atcgttcctt atgttttaca ccaaaacgtt
    12721 gttcttcgtc aatgatcagt agacccaaat cgctaaattc aatatctttt gacaaaattc
    12781 ggtgggttcc tacaacaata tcaacttgac ctgtacgcag ttgttcgatg gtttcttttt
    12841 gttgctttct tgttctgaaa cgacttaata gcccgatatt tacggggaaa ccttcaaatc
    12901 tttccagcat cgtttcatag tgctgctgtg ccaagatcgt tgttggaact aaaaaggcta
    12961 cttgtttgct ttcctttatc gctttaaagg ccgctcgaag cgctacttct gttttcccat
    13021 aaccaacatc acctacgagt agtcgatcca ttggtttttc tttttccata tcccgtttga
    13081 tctccgctgc acttctcaac tggtcatcag tttcagagta ggggaaggca ttttcgaatt
    13141 ctttttggta ggcgtcatca ggtccaaaag catatccttt ttctgactct cttgcggcat
    13201 ataatttgat tagatcgtca gcgatatcct cgatttttga agagactttt cgcttggttt
    13261 tcgtccattc acttccgcct agcttattga tgcgaggcgc tttggcttca gaggcgacat
    13321 atttttggat cagattcagt tgagtaacag gaataaacag tttgtcgtcg ttttgataca
    13381 aaatagtcat atagtcttgg tgaacgccat ctacttctag cgtttccatc ccaatgtatt
    13441 tcccgatacc atgattggca tggacaacgt aatctcctgc ttttaactca ttatagcttt
    13501 tcaatcgctc tgcgtttgtt actgtttgac gtctcgtttg ttttttcgtc gttttttgga
    13561 aaatttcttt ttctgtgata gctactattt tttcttgagg aagttcaaaa ccagcctgca
    13621 aagctccttc aactaattgt acctgtcctc tgatcaatgc atttttttct gtttctacta
    13681 ctaatatgtc ttcatctcga agcatttgtt ctgctttgcg tattctgtcc tttgtcggaa
    13741 taaagatcac aacagtctgt ttttgcttgc gccaacggtc catttctgtt ttcagcaatg
    13801 gcatttgtcc gaagaactgt tgcatcgtcc gatattgaaa attatggatt gcttggaaac
    13861 gaagatttcc catccctttt tggaagagtg agaaaaaggt tgtggtgaac ttttccttct
    13921 gcacgatttt ttgtatatct gctgaaaatg tctgctcaga aaacacccgc aattcgctga
    13981 ttttttgagt ctgccattct gccgcttccc tttcgatttc ccgatttgtt tccatgattc
    14041 gctgataatc atcaacgact agtaaactat ttgaagggaa ataatccaag atcgtcacag
    14101 attcttggta aagaagatct gagtagaatt ttgcttcttc tgtcgggaca cctgcttgcc
    14161 agcttgaagt cagctgaccg aagtaatctt gcaaaaactc gcggtctgct tcttctgtgg
    14221 tcgcagcaag ccgtttttct agcatttttt gcatttgctc tattccatgt tctagatcct
    14281 ctggtccgta gacttgttca ctcgttgggg aaacccagat ttcttccgtt ttttcgattg
    14341 agcgttgtgt ttctgcttca aaataccgca tagaatctat ctctacatca aatagttcta
    14401 cacgaacagg ataggttgtc gttaacgggt aaatatcgat aatgcttcct cgaatactga
    14461 attctcccgg ttttgcgacc atctcttctc gtacatagcc catcaaagtc aattggcgag
    14521 gaagattttc cacgtctatc tcatcaccaa tatgccaatt caattgcgcc tgtagccaag
    14581 ttttcttatt cggcagtcgt ttgtgcaaag atgcgactgg caacaaatag atacctgctt
    14641 ttttttcttg aagtgcgtta agcgttgcaa ctctctcgcc tcgcgcttct ggagaagaaa
    14701 aggccatttc agcagaaagc acttcatcca ctggaaataa atggatctga tcttgcggaa
    14761 tcacatgttg cagatcttct gctaactgat tcgcataata caaatttggc atcagaataa
    14821 tcatgttttt atttgttttc ttaaacgctc gagcaaatag aagtgttttc gctgagcccg
    14881 ctaatcctgt gattagttgt ctaggcattt tttcttctaa attgctgacc cattctttta
    14941 cttgcggatc ttttccgact aattgaataa tatccattcc ttttcctcct tcctcaattg
    15001 aatcgattca tcgcatccac gaacgaatgc ccttctatga gatattcgac tgctttaaca
    15061 gattgacaca tgctttcttc tatcaaaggc tgattttctt tgctgaaagg actaagcaca
    15121 tgctggacta ctgttttttt cccttctggc ctgccgattc ccaccttgat tcgatcaaag
    15181 acattcgtat tcaaatggga aataatactt ttgataccgt tatgcccgcc ggcacttccc
    15241 ttttgacgga gccggatttt tcccactgcc agatccaaat catcgtagat tacgactaat
    15301 tcctctggat aaatcccaaa ataagtcatt agtgggccga ctgcacgacc agattcattc
    15361 atgaatgttt gtggtttgac taaaaggatc ttttctccat tatgaaaaaa ttcggcaact
    15421 tctgcttcga acggattttt tttgaaagta gcttgatgct cgcgtgcaat tttatccacg
    15481 accataaagc cgatattgtg ttttgtatat tggtatttgg tacctgggtt tcctaacccg
    15541 acgatcattt tcatttttgt tttccaccta attctaaaaa gcagcacaaa aggctggact
    15601 gctaattagc ggtccagtcc atcgagcttt tttctttttt acacttgtca atgcatagta
    15661 taacacaaaa caaggcgttt cggctaaaag agaatcgtta ataaatgata aagaaattaa
    15721 aaatttcttc aaagtttaat gaaataattg atatataaaa atagtgaaat aacgcacatg
    15781 taagctttta catataatac aaccttgtta tctgttatat tttatagcca aatagcgtga
    15841 catggggctt gagaaatgtt agcataagca tgggaaaaaa caaatcaatg gaaggattga
    15901 tactaaatga ctgcagctgc agaaaaaaaa gatcatcaaa aagttattct tgttggagac
    15961 ggcgccgtag gttctagcta tgcctttgct ctagttactc aaaatatcgc tcaagaagta
    16021 ggtattgtgg atatcaatac tgctaaaact gaaggagacg caattgactt gtctcacgct
    16081 ttggcattta cttcacctaa aaaaatctat tctgctactt acgcagacgc acatgatgct
    16141 gacttagttg ttattacagc tggcgcacca caaaaaccag gtgaaactcg tttagactta
    16201 gtaaacaaaa acctaaaaat caaccgcgat gttgtcacac aaatcgttga atcaggattt
    16261 aacggtatct ttttagttgc cgctaaccca gtagatattt tgacttactc aacttggaaa
    16321 ttctcaggtt tccctaaaga acgcgtaatc ggttcaggta cctctcttga ctcagctcgt
    16381 ttccgtcaag cacttgcgga attagttgac gttgatgcac gtaacgtcca tgcttacatc
    16441 ttaggtgaac acggagattc agaattccca gtttggtcac atgcaaatgt tgccggcttg
    16501 caaatctatg aatgggtaaa aaacaaccca gaaatcgatg aagaagctat ggttaaccta
    16561 ttctttggcg tacgtgacgc tgcttacaca attatcgaga aaaaaggcgc tactttctat
    16621 ggtatcgcag tagcattagc acgtatcact cgtgccatct tagatgatga aaatgctgtt
    16681 cttcctttat cagtattcat gaatggcgaa tatggattga acgacatcta cattggtgca
    16741 cctgctgtta tcaaccgtca aggtatccaa aaagtaatcg aaattccttt aagtgacagc
    16801 gagcaagacc gtatggctgc ttctgctaag caattaaaag aaattctaga tgaagctttt
    16861 gctaaactag acgctgaata atctttgaac atgacggaaa acatctattc ggtgttttcc
    16921 gtttttttat tttatcaccc ttatggtttc taaatttttt cataaagtag agataacctt
    16981 cgtcttttcc tctaaattat gctatcatga gaccgttcca ccctaaactt ttacttaagg
    17041 agttgtcgat atgacaagat cttcgcatcg aaaaaaatcg aaacatgttg ctttgctttc
    17101 agttcttggt gttctcttag tgctgatcag cttttatacc tatcgcagta catactacac
    17161 aaagcatttt ttgccgaata cagaaataaa tggaataaat gtcagcaatc taacagtcga
    17221 aaaagcaaat gaaaaattaa aagaagctta ttctgataaa aaactggcta ttaaagaaga
    17281 tggaaaagtc tggcaggaag taccaaaatc cgagctcggc tacaaagatg atttcacttc
    17341 ggagctttct ccgatcctaa atgaacaaaa cggatggact tggggaatga cttatgtctc
    17401 agcggcagaa aaacaagaaa tagatcctgt cagtcaaaac caccaaaaac tagacactac
    17461 cgttcagaca ttgacaacta agctgactga tttgaacaaa gaccggacac ctactactga
    17521 tgcaacgatc gaaaaagcag gtgactcttt cgttatcaag cctgaagtca atggaaatac
    17581 gatcgacgtc gatgctgcgg tcaaacaatt aaaaagtgcg gtaaactctg gtaaagatac
    17641 aattgaattg actgaattca aagaaaaacc aaaagtaaca tctgaagaca gctcactgaa
    17701 agaacaactc gcatccatga atgctatcgc aaatgtaaaa gctacttaca gtataaacgg
    17761 tgagactttc cagatcccat caagtgatat tatgagttgg ctgacctaca atgatggaaa
    17821 agtcgattta gatacagaac aagtacgtca atatgtaaca gatttaggca caaagtataa
    17881 cacaagtacg aatgacacaa aatttaaaag tacaaaaaga ggagaagtta cggtcccagt
    17941 tggcacttac agttggacga tccaaacaga cagtgagaca gaagcattga aaaaagcgat
    18001 tctggcaggc caagatttta ctcgttcacc cattgtgcaa ggtggcacaa ccgctgatca
    18061 tccattgatc gaagatacgt atatcgaagt tgatctggag aaccagcata tgtggtatta
    18121 caaagacgga aaagtggccc ttgaaacaga tatcgtttcc ggaaagccaa ctacacctac
    18181 acctgctgga gtcttctatg tttggaataa agaagaagat gcaactttaa aaggaacaaa
    18241 tgacgatgga acaccttacg agagtccggt aaactactgg atgccgattg actggacagg
    18301 tgttggtatc cacgattcag actggcaacc tgaatacggt ggagacttat ggaaaacccg
    18361 cggttcacac ggctgcatca acaccccacc aagtgtaatg aaggaattat tcgggatggt
    18421 cgaaaaagga acgcctgtat tggtcttcta acaaaaataa tatataaaaa gaaagcaccc
    18481 gtacgattgg tacaggtgct ttctttttat tatctaacaa tgtgctactt acatttcagc
    18541 agcagtaaag acttctgaaa catcatcatc gtcttctagc ttatctacta gacgttccaa
    18601 ttgctctttt tgttcctcat ttaaatcaat cgtcgtttgt ggaatcatcg tcaattctgc
    18661 ttgcgccaaa gtgaactctt tttccaactc atctcgtaca gcagcaaaat cttctggtgc
    18721 agtataaatc tcgaatactt caggagaagt ttgcagatct tctgcccccg cctctaatac
    18781 atcctcaaac atcgtctctt catcaacagt caacccatcg cgttcaatag cgatatatcc
    18841 tttgcggtca aacaagtaac tgactgaacc cgtttctccc agtgatccac cgtttcgagt
    18901 aaaagctact cggacatttg tcgctgtccg attacggtta tctgtcaatg catggactaa
    18961 gattcctact ccacccggac catatccttc atacgtgatt tcatcgtaat tcgtttcatc
    19021 tacggcactc gtagcctttt taatcgcccg ttccacattg tcgttaggca tatttgcagc
    19081 ttttgctttg tccacaacaa gccgcaaagc tggattcata gatggatcag gaccgcctgc
    19141 tttagctgcc atataaattt cacgagaaag tttctgaaag actttccctc gttttgcatc
    19201 ttgggcattt tttcttcctt ggatattatg ccatttacta tgtcctgaca tgatttttcc
    19261 tcccttgttc ttttgagaat acacttctat tctagtacta tttcacaaaa aaacaaagcc
    19321 acagccaatc tataaacgct tcttgaatgc cgcaaaaagc acacataata tcacagcagt
    19381 cagagcaccg atcgaatcca acatgacatc ttggaacata ggtgttcgtc caccggtcat
    19441 catctgatgg aattcgtcca aacctgcgta ccctgttgct gaaagccaag caaggatcgc
    19501 tgtcagccac caaattttta gcttggggaa aacacctaaa aacaagctgc ctcccaaaat
    19561 aaaataggta ccgaaatgtg cgcccttcct taaaaagaac tctaaaaatt tggcgtagcc
    19621 cagatggttg atactcacca tacttccacc ataattaaaa cgtatacccg ctaatgtgtc
    19681 tttaaatggc tgattaggca gccagctttc taatcgcgaa acttgtgatt gctgtccgta
    19741 agtttgagaa gaactgtaaa ataagattat aacgactatc agtgcgatta ctaaataaat
    19801 atttccgttt ttcatttgtt tttttgaaga attcataagt cacctctgta ttttatctta
    19861 gacttttttt gaagaaacaa caatcatttt catagagact tcttccataa aaaagtgcta
    19921 tacttaattt tgtattacaa tatgaaggga gttttttcat gagttattca ttaaattgga
    19981 atctagattc tattttttcc ggaggcagtc attctgatgc tttgaaccaa cggatgaagc
    20041 aattggaaga ccaaatgaac gagtattatc accgcgtaac aaaatggtca cctagttctg
    20101 acaatgcaga gcagttaaac gctattcttc aattgcaaga aacgattacg aatggtttta
    20161 cccaatgcag cagctatatt actgcattgc tttctgccaa tgtcaatgat tcagatgcaa
    20221 aggtcttatc aggcaagctt tacgcaatgc tgcctcgtct gcaatcagcc gaaactgtat
    20281 tgtcaaagaa atttgcagaa atatctgaca atgattggaa tcagatgctt tctcaatctt
    20341 cgtttgaaac aattgctttt cgtttaaacg agattcgtcg tgatggctca caattattat
    20401 cagaagctga agaaaacatt ataaatacgc tttctttaga tggtctaaat gcttggagca
    20461 gtcattatga tacgattgta gccagcattt cgattccctt cgaacaagat ggacaagtag
    20521 tcgaattatc tgctggacaa gccttcaata agatgatggg cgatccagat ccaaaagtca
    20581 gagaaacact tttcgcagca tgggaagaag cctggaaaga aaaggcaccc ctcttcacgg
    20641 atactttgaa tcatttagat ggttttagac tttctgacta tgaacttcat ggtgtcacag
    20701 attttctaca aaaaccatta gagtacaatc ggttgaagaa agaaacattg tctgtcatgt
    20761 gggatacaat ccagaaaaac aaacaacccc ttgttaatta cttgactaga aaagctaatc
    20821 ttttcggtaa agaaaaaatg gaatggcaag atcaagatgc acctattatt ttaggcgatt
    20881 tgaaagaaaa aacctttagt tttgacgaag cagcagcatt tattatcgaa aactttaaca
    20941 aattcagtcc aaaaatggct aaatttgccc aatctgcttt tgaaaagagc tggatcgaag
    21001 cagaagatcg tcctgggaaa cgtcctggtg gttattgtac tgagttacca gaaacaaaag
    21061 aatcaaggat ctttatgacc tacagtaatt ctgttaatga ggttgcgaca cttgctcatg
    21121 aactaggaca tgctttccat agcagcacga tgtgggattt accttcttta aatcgcgaat
    21181 atgccatgaa tgtcgcagaa acagcaagta cattcgcaga attgatcgta gccgatgcta
    21241 cattaaaagt cgcaaaaaca aaagaagaaa aaatcaattt gctagataca aaactgcaaa
    21301 atgctttagc tatgttcatg aatatccatt cccgattcat ttttgaaaat cgattctatg
    21361 aagcacggca agaaggatta gtctcagaag ataagatcac agagatgatg gttgaggcgc
    21421 aaaaagaagg ctatcaagga gctttagcta cttaccatcc atatttctgg gctgcaaaat
    21481 tgcatttctt tattgatgac gtaccgtttt ataacttccc atacacattt ggctacctct
    21541 ttagtttggg catctatgct tacgccaacc aaaagggagc aaattttgaa gaagaatata
    21601 tccatttact acgcgatact gcctcaatga cgacggaaga tcttgcgaag aaacatttga
    21661 atgtcgatct tacccaacca gatttttggc aagcaggtat cgacatggtg actgaagata
    21721 tccaaacgtt catggaattg acagaagaat ttatctgatt tctattttat cacaataaaa
    21781 aaagagttag tccagaatgg gctaactctt tttgatgtgc gccctgcatg ggtgaaaact
    21841 tggtggtgaa agtccactac aggcttggca gtaggaactg ttagcgaaag acaaggcggc
    21901 aatcgtgagg ttgtggctga aggaagtcgg acgcaaactc ctgaactgac gaacagaaac
    21961 tagatacaag gctgaattag gtcggataag tcttcatcac aagacaaagt ccaatactgc
    22021 ccgaaaccta tacagtaaat ctagcagtta catgggagga aagttttcac tcttaccggg
    22081 ggagatctca tgagggtgtt gtgggcgttg aatgaaaaca aaccagcaca acgatcatgg
    22141 cgacatgatg gtgaatcatg agaagtcagc cgaggtcata gtagtaacga cactgaccgt
    22201 tacgaaggac tgaacaataa gaatcttgaa taatttagga ggtgtgagaa gatgcgacga
    22261 ccgcagaaaa caagaaaact tggctatcat caaagagcta gtgtggaaca cgaagggtat
    22321 gatgaagtgc gcagcacttc ttgcggtgaa cagaggaaac aagatggtgt agaaaatctg
    22381 tttgggagaa ttctagatcg gaataatctc aatcaagcgt atcttcaagt agtcagaaat
    22441 aaaggggcgg ctggtgcaga tgggatgacc gtcgatcaac tgcttcctta cttgaaagag
    22501 caccgcgagg aattactatc caatttacgc caagggaact ataaacctca gcctgttttg
    22561 cgagtagaaa taccgaaacc aaacggcggt gtaagaaaac taggaattcc cacggttatt
    22621 gatcgtatgc ttcaacaggc aatcaatcaa gtgttacaac cgctatttga accagaattc
    22681 tcagataata gttatgggtt tcgcccaaat cgcagcgcac atgacgcagt gaagaaagca
    22741 aaatcttatt atgaacaagg ttaccgatat gtggtggaca ttgatatgaa agcctacttt
    22801 gacaccgtaa atcacgataa gctgatgtat ttcattgagc ggaaagtaaa ggacaaacaa
    22861 gtcctaaaac tgatccgtca atacttaatg agtggtgtaa tggaaaatgg actcatcaca
    22921 acaactgaag aaggaacgcc ccaaggaggc aatctctctc ccctgttaag taacatctac
    22981 ctgaacgaat ttgatcaagt gctagaaaat ctaggacata aatttgttcg atacgccgat
    23041 gactgcaata tctatgttag aagcaaacga gcaggacagc gtgtgatgaa gaaatccatt
    23101 caatttctcg aagaacaact aaagttgacg gtaaatcgag aaaagagtgc ggtaggaagt
    23161 ccattgaaac gaaagtttct tggattctgc attctgccaa caaagaaagg tattaaaatt
    23221 cgccctcacg caaaagcaaa acagcgtgtg aaaagcaagc tcaaacaact cactaaaaga
    23281 aaccgtggaa gaagtatcca acttatttta aaagaaatca agcaactaat gactggttgg
    23341 atcaactact atggaattgg tgagatgaaa gaattcatga gggagttaaa cggttggttg
    23401 aagcgaagaa tcagacaata tatttggaaa caatggaaga atccaagaac caaaagaaaa
    23461 aatctgattc gtttagggat cgataaagcg aaagcgtatg aatggtcaaa tacaagaaaa
    23521 ggtatttggt cagtctccaa aagtcatatt cttcatcgat cattaacaga caaagaactg
    23581 gcccgccaag gatatgagga catctccttg aagtaccagt tcgtacactc aacttattga
    23641 accgccgtat acgggtccgt acgtacggtg gtgtgagagg ggcggaaggt cagtt
//
LOCUS       DBBGSP010000047        23007 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000047 DBBGSP010000000
VERSION     DBBGSP010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.047"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            133..2604
                     /locus_tag="ACIZE9_002127"
     CDS             133..2604
                     /locus_tag="ACIZE9_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGC6093973.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYIYQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2707..4443)
                     /locus_tag="ACIZE9_002128"
     CDS             complement(2707..4443)
                     /locus_tag="ACIZE9_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6093974.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4440..5144)
                     /locus_tag="ACIZE9_002129"
     CDS             complement(4440..5144)
                     /locus_tag="ACIZE9_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6093975.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5275..5778
                     /locus_tag="ACIZE9_002130"
     CDS             5275..5778
                     /locus_tag="ACIZE9_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HGC6093976.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            5738..6076
                     /locus_tag="ACIZE9_002131"
     CDS             5738..6076
                     /locus_tag="ACIZE9_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGC6093977.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6097..7515
                     /gene="ffh"
                     /locus_tag="ACIZE9_002132"
     CDS             6097..7515
                     /gene="ffh"
                     /locus_tag="ACIZE9_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGC6093978.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7627..8205
                     /locus_tag="ACIZE9_002133"
     CDS             7627..8205
                     /locus_tag="ACIZE9_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGC6093979.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8209..8730
                     /locus_tag="ACIZE9_002134"
     CDS             8209..8730
                     /locus_tag="ACIZE9_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HGC6093980.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(8809..9363)
                     /locus_tag="ACIZE9_002135"
     CDS             complement(8809..9363)
                     /locus_tag="ACIZE9_002135"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGC6093981.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9616..9891
                     /gene="rpsP"
                     /locus_tag="ACIZE9_002136"
     CDS             9616..9891
                     /gene="rpsP"
                     /locus_tag="ACIZE9_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGC6093982.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            9903..10154
                     /locus_tag="ACIZE9_002137"
     CDS             9903..10154
                     /locus_tag="ACIZE9_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HGC6093983.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10279..11070
                     /locus_tag="ACIZE9_002138"
     CDS             10279..11070
                     /locus_tag="ACIZE9_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093984.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11240..11761
                     /gene="rimM"
                     /locus_tag="ACIZE9_002139"
     CDS             11240..11761
                     /gene="rimM"
                     /locus_tag="ACIZE9_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGC6093985.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            11751..12512
                     /gene="trmD"
                     /locus_tag="ACIZE9_002140"
     CDS             11751..12512
                     /gene="trmD"
                     /locus_tag="ACIZE9_002140"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGC6093986.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12648..12995
                     /gene="rplS"
                     /locus_tag="ACIZE9_002141"
     CDS             12648..12995
                     /gene="rplS"
                     /locus_tag="ACIZE9_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGC6093987.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13368..14030
                     /locus_tag="ACIZE9_002142"
     CDS             13368..14030
                     /locus_tag="ACIZE9_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093988.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            14109..17336
                     /gene="fss3"
                     /locus_tag="ACIZE9_002143"
     CDS             14109..17336
                     /gene="fss3"
                     /locus_tag="ACIZE9_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HGC6093989.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            17450..17764
                     /locus_tag="ACIZE9_002144"
     CDS             17450..17764
                     /locus_tag="ACIZE9_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGC6093990.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            17777..18151
                     /locus_tag="ACIZE9_002145"
     CDS             17777..18151
                     /locus_tag="ACIZE9_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGC6093991.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            18161..18505
                     /locus_tag="ACIZE9_002146"
     CDS             18161..18505
                     /locus_tag="ACIZE9_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGC6093992.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            18576..19928
                     /locus_tag="ACIZE9_002147"
     CDS             18576..19928
                     /locus_tag="ACIZE9_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGC6093993.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            19988..21130
                     /locus_tag="ACIZE9_002148"
     CDS             19988..21130
                     /locus_tag="ACIZE9_002148"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HGC6093994.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            21155..21409
                     /locus_tag="ACIZE9_002149"
     CDS             21155..21409
                     /locus_tag="ACIZE9_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6093995.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            21665..22849
                     /gene="mobT"
                     /locus_tag="ACIZE9_002150"
     CDS             21665..22849
                     /gene="mobT"
                     /locus_tag="ACIZE9_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HGC6093996.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            22846..22983
                     /locus_tag="ACIZE9_002151"
     CDS             22846..22983
                     /locus_tag="ACIZE9_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HGC6093997.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
BASE COUNT         7645 a         4087 c         4955 g         6320 t
ORIGIN      
        1 tttttttttg ctatatgaca ggaatgaaag gtgtttgcaa gcttaatgtg aggaacactt
       61 tccatatctg ttctatactg gataggagaa gtttggaaat atccagaaaa cgaaatcaat
      121 cgaggtagcc acatgaagaa taaatggata aatcgaagta aaaaaaagaa agtaacacaa
      181 agatcatcag ataaagtcat ccgtcttttt ccatcgtata aagaaggatt aacggcagat
      241 caagtcaagg aacgaataga aaaaggtgca gcaaataatt cagtcgatcc cacattcaaa
      301 acaaatcagc aaatcgtatt ggaaaacata tttacgtatt tcaatttgat ctttcttatc
      361 ttagccattt tgctttgttt agtagaatcc tataagaact tgactttttt accagttatc
      421 atagccaata caggaatcgc catttttcag gaaattcgat ccaaaaagat cttggacgaa
      481 ctaaatgttt taaatacagc aaaagtcaat gtcatacgag acgggataga acaaacaata
      541 gatatagaag accttgtaat agatgacatt gttattttag agactggata tcaaattcca
      601 gcagatgcag aggtcgtgga agggaaactg caagttaatg aggctttatt gacaggcgaa
      661 gcagatgaaa taaccaaaga aataggtgat ccattaatgt ccggcagttt cattgtttcc
      721 ggaaaagctt acgcccgatt agacaaagtt ggagcagatt cgtatattta ccagctgaca
      781 gtcaaagcca agacaatggg agaaggagaa cagtcggaga tgattgcttc tcttaatcaa
      841 ttgatcaaat ggattgggat catcattatt cctatcggta tcctgctttt ttctcaaagt
      901 tactttttta atggaaacac gatcaaagaa agtgtcgttg caatggaagc agcattgatc
      961 ggtatgatac ctgaaggact gtacttgctg acgacgattg cattagcatt aagtgcgact
     1021 aaactagcaa agcaaagagt tcttttacac aatatgaaaa gcattgagac attggcaagg
     1081 gtaaatgtcc tttgtgtaga taaaacagga acgatcacag aaaataaaat gtctgttcaa
     1141 aaaatgatcg tctctaaaaa acaagaaata atcagtcagt cagatcaatt ggaagcatgc
     1201 attgctgact atgcaaaagc gatggcagga gacaatgcaa caatggaagc tgttaaagca
     1261 tattttacaa aaaccactga tcaatcctat caccatgtta ttcctttttc ttctgtccaa
     1321 aaattcagca gtgtagcgtt ggcagacaag gtgtatgttt taggagcgcc cgaaatggtt
     1381 ttgcgcgatc aattgccgga atatgcggaa gagtttgttt ctttcgctga aaaaggctat
     1441 cgcgtgttgg tctttggtgt gtacgatggg attcttgaag aaccagtatt gacagaagca
     1501 gtcacaccat taggctatat tctgattgct aatcctatca gaaaagaagc aagagccaca
     1561 tttgattact tcaaaaaaca gcaagtagcc atcaaagtga tttctggaga taatccgctc
     1621 accgtatcca atgtagctgt ccaagcaggg atttcacatg ctgatcagta cgttgatgca
     1681 tctaaattat cagaagaaga atatgaagca gctgtcgaaa aatatacagt ttttggacgc
     1741 gtcaagccag aacaaaagaa aatcttcgtt caattgataa agcgtaacaa tacagtagct
     1801 atgacaggtg atggcgtgaa tgatattcta gccatgaaag aagcagactg cagtatagcg
     1861 atggcttccg gaaatgaagc cgccatgcag gcctcacaag tggtcttact tgattctgac
     1921 ttttcacgca tgccagaagt tgttgcagaa ggacggcgcg ttgtgaacaa tattgagcga
     1981 tcagccagct tgtttttagt gaagaatatt ttctcctttt tgctctcact gttttcagtg
     2041 atctttgctc tgacctatcc tttagaacca tcacaaatca cattgattag tttgtttact
     2101 atcggacttc catctttctt gcttgctcta gaagaaaaca aaaagcgaat cagagggaaa
     2161 ttcatcatga atgtgatgga aaaagctgtg ccaggtggac taacagatat gatcgtagtc
     2221 ggtgcgttgg tgatctgcgg ggtgactttg aatctaaata aaacagatgt ttctacagca
     2281 tctaccatgc ttttgattgc agtagggttc ctcgttctct ataaaatctg ttcaccgctg
     2341 aataaattca gaagtcagat cattcttttc tgtgctagcg gtaacttttt ttcggtcatc
     2401 tttttgcata agctgttttc aatcaccggt atctcagctg tatcactttt gctgttgagc
     2461 attctatttt tctcggcaga ttcgattttt aggcatttga ccacattggt agaatatttg
     2521 tttgaacgta aaaatgaaaa agagcaaaag ccgtttagtc gcgtagctaa aaaatttcta
     2581 tcgatattta aacgagaaaa ttgacgaaaa gtatctcaaa aaagagtaaa aaagaacaac
     2641 cactcgtgta tctttcgaag caggatgagt catccaactt taaaacgcac gagcagttgc
     2701 tcttttttac attttcggaa tggtaacggt gaaagtcgaa cctgttccaa gatgactgtc
     2761 tacagtaatc gtaccattaa ggagttgcac gtagtctttt acaatcgcta accctaatcc
     2821 ggtcccgcct gaatgtcggc ttcgcgcctt gtctacgcgg taaaaacgct caaagatccg
     2881 ttcctgatcc tcaatgtcga tacctatacc aaagtcttgg acagaaaacg atagatcatc
     2941 tgttgcctga tagcggataa taatctcgct gtcgcttttt gaatattgga cagcattttc
     3001 aattagattt ttgataattg gataaaggat atctgtttta gtagtaaatg gttcgttctt
     3061 tccaatcaat cgaatcgtca accgtttctt ttcgatgatt ggctgataat tttgaacgat
     3121 ttgctggaaa taaggttctg tataaattgt ctggatctcg taagaattct cgccatcttt
     3181 tgacagctgg atgatttccc gaatcagttt atctaaccgg atcgcatctt tttgcatgat
     3241 ctcaagaaaa gaagtcagag tttgcgggtc atcttttgca ccatccagta aagtctcggt
     3301 aaaaccaatc agtgaagtca caggagtttt taattcgtga gagacgttgc caacgaaatc
     3361 cttttgtagc ttttctaaac gtcgcacttt cgttaagtca tacgccaccc ctagaatctg
     3421 tccggtacct tctgaattag taaagtagcg caaactcaag tctaatgtct gccgaccttc
     3481 tgtaagggtg atctcctgat ggatcagcgg atgctcagga gtcacttgat gaatcagctg
     3541 aatgagtttt ggctcttgaa tgacttctgt gtaccgctgt tcaggttgat agcttaccac
     3601 gtttaaatgt agctgcatct ttggattaag cagtagtaaa cgagaatcag catcatcaat
     3661 caggaatacg ccaatcatca gttcgttcag taacgtatat aattgctctt ctgtggtagt
     3721 acacgcccga tacatcttac tcatttgttc gctcaacgca ttaatcgtct gatacaattc
     3781 ttcccattga tcgggtgttt gcatgattac ttccgcctga ttaggatttt gcaccatttt
     3841 ttttagtacg ggcagcacgg ttttcaatgg ctggtttttt tgatagatca gataatagat
     3901 cattcctgca agaacaagga agaaagacag aaagaagaaa aagacccaac ggcgaaaact
     3961 ctcagttctc ggtaaaaaac cgcttgtcgg ttctgcgata cgtaaaatgg cttctaactg
     4021 gccacttttt ttgactggta atgcgacata taaaagatcc tcattcaaag tagtactttt
     4081 gcgcaaagcg ctacctaggt tcccaccatt caatacggct ttgatttcgg gacgggagtt
     4141 tcgctgttca ttcaatgttt cattgtttgt gtcaaataag atctttccag tagcatccat
     4201 taaagtaatc cgttcgttcg actgatggac gaattcttcc aaagcagttt tgttttgcgc
     4261 tgcttggagg ttttcgacat ctaattgccg gatcagcagt tgtgcttttt ttgtcaggta
     4321 gctttcttgc tgttccacga tctgctgttg aaaataatgg gaaatcaatt gccagccacc
     4381 aaaaaacaaa ctaactaaaa gaataagaaa gaagagacgt tcataaattt ttttccattt
     4441 catcgtttgg gttcctgaaa cttatagcca aatcctctaa tagtcaccaa gtactttggg
     4501 tgttttggat ctcgctcgat tttttctcgc aaatgactaa cgtgtacatc tacgattcgg
     4561 ctttgtcctg cgaagtcaaa attccaaatg cggtctagca atgtgtctcg gtcgatcaca
     4621 cggtcttttc gtttcatgaa ataaacaagt aattcaaatt ctttcggtgt tagttcaatc
     4681 agatggtcgt ctacggtcac ttgataattg gtcaaatcag cagtgatttg tccaatcgat
     4741 agatattcag gctcagcttc atcttttgat tgcttacgag gttcaattcg tctgaatatt
     4801 gctttcatac gggctaatac ttcgcgagga ctaaatggtt tggtcaaata gtcgtcagca
     4861 cctatttcta ggccaatgat ccgatccact tggtcatctt tagccgtcag catcaaaatc
     4921 ggtgtttcat ttttttcttg acgcagccgc tgagtgatct ccatgccatc catcgttgga
     4981 agcatcacat ctaaaatgat gaaatcaaat gattgttcta atgctaattc taatccttcg
     5041 cctccatctg tggcactggt taccttgtag ccttcttttt ccaaattgaa cgtcaagagc
     5101 gttacaatag aaggttcatc atcaacaact agtatttttt tcattcaaat ctcctttaaa
     5161 taggtttcat tctgtttata ttttagcata gaatcagtac aaagggctat tttacaaaag
     5221 aaataaatgg tataatagga aggcactttg ctgaatagaa aggaagagca gtcaatgatt
     5281 ggaatcagtg catgtttagg cggtctggcc tgtcgctatg atggacagaa aaaagaagta
     5341 ccagaattga tggaactagt tgaaactgga gaagctgtca tggtctgtcc agaagtgatc
     5401 ggcggattac caattcctag agatcccgct gaaatcattg gtggaaatgg attcgatgtg
     5461 tggaaagatc aagcaaaagt atggacgaca agcggcgaag atgtaacgga agcgtacaaa
     5521 aatggcgcga tcaaagccta tcaaaaattg caggaaaaac acattgatct agtcatcatg
     5581 aaggaaaaaa gcccttcatg cggaacccat tcgatttatg acggaagttt ttccggaata
     5641 aaaaaaaatg gtgccggagt ggctactgct tattttattc agcaaaaaat gactgtgctc
     5701 tctgatgaag aatggctgaa aactagaggt gagcagaatg gaaatcgaaa agaccaatcg
     5761 aatgaacgcg ctctttgaat tttattcgac cttattgaca gaaaaacaaa tgaactacat
     5821 ggaattatat tatgcagatg atttttcatt aggtgagatc gcggaagaat acgaagtaag
     5881 ccgacaagca gtatatgaca atatcaagcg gacaagcaag atcttggagg attatgaaaa
     5941 aaaactccat cttttttcta attatattgt tcgagaacag gtattggaaa atatgactgc
     6001 atatattaca gataagtacc cggaagataa aaaactactt gaatatgtac agcaaattca
     6061 agcaatcgaa gaataaataa aaggaatgaa gaaaatatgg catttgaaag cttaactgaa
     6121 cgtctccagc aggcgatggg aaaaataaga aaaaaaggaa aagtatcaga agctgacgta
     6181 aaagaaatga tgcgggaaat ccgccttgcc ttactagaag ccgatgttaa cttgcaagta
     6241 gtcaaagatt ttactaagcg cgtacgcgaa cgtgcggtag gggcagaagt gctggaaagt
     6301 ttatcacctg cacaacaaat cgtaaaaatc gttgatgaag aattgacgat cacacttggt
     6361 tctgaaacag cagagttaaa taaatcacca aaaataccaa ctgttatcat gatggctggt
     6421 cttcaagggg caggtaaaac gacctttact ggtaaattag ccaattattt aaagaaaaat
     6481 gaaaatgctc gtccgctcct aatcgcaggg gacgtatatc gaccagctgc gatcgaccaa
     6541 ttgaaagtat taggtcaaca gctagacgtt cctgtatttg atatgggaac tgaagtcagc
     6601 ccggtagaga tcgtccgtca agggatggag ttagcaaaag aaaagaaaaa cgactatgta
     6661 ttgatcgata cggcaggacg tctgcatatc gatgaaacat tgatggatga gttgaaacaa
     6721 atcaaagaat tgacgcaacc aaatgagatt ttgcttgttg tcgatgccat gactggtcaa
     6781 gatgccgtca acgtagctga tagcttcaac cagcaattag gtattacagg ggtcgtcatc
     6841 actaaacttg atggggatac tcgaggcggg gcagcactat cgatccgctc agtgacaggc
     6901 gcaccaatca aattcatcgg ttctggtgaa aaattgactg acttagaagt attccaccca
     6961 gatcgtatgg ctagccgtat ccttggtatg ggggatatgc tgacattgat tgaaaaagcg
     7021 cagcaagact acgacgagaa aaaagcggaa gaacttgcac agaaaatgcg ggaaaattca
     7081 ttcgatttca atgactttat tgaacagctt gatcaagtga tgggtatggg cccactggaa
     7141 gatctaatca aaatgatccc aggaatgaat caagtccctg gaatcgaaaa cgtcaaggta
     7201 gatccaaaag atgttgaacg caaaaaagcg atggtttatt ctatgacgcc agcagaaaga
     7261 gcaaatcctg atctgttgaa cccaagccgt cgtcgccgaa ttgctgccgg ttctggaaac
     7321 agtgttgttg aagtgaatcg aatgatcaaa caattcaagg aatcaagaaa aatgatgcag
     7381 caaatgtcca aaggggatat gaacatccca ggtatggacc aaatgtttgg ttcaggcgtc
     7441 aaaggaaaac taggcaaaat ggcgatgaat cgaatgatca agaaaaataa gaagaaaaag
     7501 aaaaaacgga aataagatga aaaaaacagc ttcggtacag actgaaaatg tctactgccg
     7561 gagcttttct atcagcaatt tttattcttt actaatacaa ttactctaaa cgaagaggtg
     7621 gcacagatga gatgtccgtg gagtgaacaa acagaaagta tgcggcaata tcatgatact
     7681 gtctggggtg ttcctgaata tgatgaccaa aagctgttcc gaaaattgat gcttgatatt
     7741 aatcaagccg gattgagctg gcagacgatt ttaaataaaa gtgaagcatt cgatgaagca
     7801 tatgatcgat tcgatatcaa aaaagtcgca aattatggag aaacaaaaat cagtgaacta
     7861 atggaaaaca aaggaattat tcgtaaccga agaaaaatcg aagcagccgt ccaaaacgcc
     7921 aaagcagtct tgaaaattca agaagaaatc ggcagttttt cagagtatct ttggtcgttt
     7981 tctaatggaa aaatcgttga ttcttcttat cattcacaag aagaagtccc aacaacaagt
     8041 cctctttcag atgaattagc aaaagatcta aagaaaagag gatttaaatt tatcggaagc
     8101 acaacaatct atgctttttt agaagctgtc gggatcatca atgatcacct tgacagttgt
     8161 ttccgcaaag aagaggtcgt acgtatcggc agaaagggcg aataaagcat gcgaaaaatc
     8221 atattttatg gtgctataag tttagatggc tatttggcaa cgaaaacgga tgatcttcaa
     8281 tggctttttg acactccaac aggtaagcaa actacttatg aagcttttta tgaaacaatc
     8341 gatacgacca tcatgggcag aaaaacttat caggaagcaa aaaaatattt ggagaccgaa
     8401 gcaatttatc cagagaaaaa gaatttcgtt ttttccaccc acgcacaatt acaattgcca
     8461 gatgctgagg tcgtaaacga agatcctgtt gcttttctaa aaaatctaca aatgacagaa
     8521 ggaaaagata tctgggttgt gggtggcggt cgattgatca aaccgctatt ggaacatcaa
     8581 atgattgatg aatggtatat ccagattacc cctgtattat taggggacgg gattccttta
     8641 ttccaaaaag gaacatatga agcgcgtttt gaaatgctag acacgacacg attcggtgaa
     8701 tttatcgaat tgcattatgt acgaaagtag aagtaaataa aataaaaaag gcaactatat
     8761 gcagaaatgt cctgtacata gttgcctttt ttattaccgt tatgcttttt actctgttaa
     8821 tttgttagaa aaatctagat acgcatctaa aatcgtttgg aagaaactta atgttccttc
     8881 aacgatatta ccattttcat caattagatt cgcaacgttt ccgatatatg cttccggttg
     8941 ctgcaaggtt ggcacattca aaaagacaag tgattggcgt agatggtggt ttgcgccaaa
     9001 gccgccgatc ccacctggtg atgcagtaac gactaaacct ggtttatgat cccaaacact
     9061 gtgtccataa ggtcttgagc ctacatctaa agcatttttc aatactgctg gcacagaacg
     9121 gttgtattca ggagtaacga aaacgacacc gtctagtccc ctcacttcct cacgaaaacg
     9181 agtccattca gcaggagcct gttctggagt ttcgagatcc tcattgtaaa atggcagatc
     9241 atcgattttt acaaatacac tttcgtaccc ttcaggaagc aatttcgcaa aagcttctgc
     9301 tacttttttg ttgtaagaat cttttcttaa actaccaata aaaaatccaa ttttttttgt
     9361 catacgattt ttcctccttc aaactatcta taataatctt acaaaagata agtaactgga
     9421 gcaaataaaa acacttactg acaaaagcta catagaagat agattactta tttttaacaa
     9481 aaaagaagtc taaaatcttc tattttctaa aaaaaatcga atttaatcaa gctgtaaaga
     9541 aaaaaagctt tacagggtaa aaaaaaactg ttacactaca tcttgtgaat aaaacaatgg
     9601 aggtggaaat aaataatggc agttaaaatc cgtttaaaac gtatgggttc taaaaagagt
     9661 ccgttttacc gtatcgtcgt agctgattca cgttctcctc gtgatggacg tttcatcgaa
     9721 actgtaggta cttacaatcc tttgaaagac cctgcagaag tagttttaaa agaagactta
     9781 gttcttgact ggttatcaaa aggtgcacaa ccttctgaca ctgtacgtaa catcctttca
     9841 aaagaaggcg ttatgcaaaa acaccacgaa gctaaattct caaagaaata aggtgaccgg
     9901 atatgaaaga tttaagcgac ttagtcttaa caatcgttcg tccgctagtc acttatcctg
     9961 atcaagtcaa gttagacgtc gtagagtcga aagactttta cgagtacaat ctaacagtgg
    10021 ctcctgaaga tattggccgt atcattggaa aacaagggcg tgttgctaaa gcaatccgca
    10081 caatcgttta cggtgttcgg atcaatgcac cgaaaaaagt gcgtttgaat atcatcgatg
    10141 ataaggaaaa gtaaataaac gtgctgtact cgaattttcg agtgcagctt ttttgttttt
    10201 tttattaatt gaagaaatga ttatttggca aaacaagcaa gaaagcgtat ccttatagga
    10261 ggagggagtg aacagccaat gagaaagaaa atgttattta ttccatttgc tctattgtta
    10321 agcgcttgta gttcggttac tcaagaatca gacaatacac atctatcaag cagtatatct
    10381 gaaactgtta ccagtccaga aaaaagtagt accaaaacgg cttccaccac tgaacaaaca
    10441 atggctacct caaataatga gaaaaagact gctttagacc agttgaaaga acaacagcca
    10501 aatgttccca tgcctctaga tgtaccagtc tcttcaggct atctcaatat cgcagcgaca
    10561 catacaaagc aaggttattc tattttatat tacagaacag atcgtcccct cgggttgaat
    10621 gctgacgaat tgaatcaaga aacgcctatt gcaacctatc tatatcaata tgggtttgct
    10681 tctagtcaag aaacaatcca agttttgcag ccatttgaga tcgacacaaa tggtcagcaa
    10741 gtggacttag gttctcgaat cacagggtat cagcaaggtg cagcaggttc aagttttctt
    10801 gaatggcaag aaggaaactg gcgtattcga atccgtggga ataatataga aggccaagat
    10861 cccttactat tagctaaaga aatcgtagct tatttggaag aaaacagtct accagcacct
    10921 gaacaatttg gtaaaattac tgttgatatg ggtgatacga cgaatcgagc cgtagaagta
    10981 agctggcaag aaccgaaaaa tgcctatacg atcactcatc aagatcctat gtctgcgttg
    11041 aagatggcag tttctatgaa gaggttgtga aatcagcgcg ctgatctgag cccatcattt
    11101 aactccaagt cacaggaagt aatcaaaaat agcacgccgc atttttgcat aattttggct
    11161 taatacctta aaagaaaact agaattgcct cttcacacat gctaaaataa aacagacaaa
    11221 aaagaaatgg ggatataagt tgactgaata cttgaatgta ggaaaaatcg taaacacaca
    11281 aggtatcaaa ggcgaagtcc gtgttatctc aacaacggat ttcccagaag aacgttacaa
    11341 aaaaggaacg gtgctaacac tattccaaga cggaaaagca cctgtggaat taacagtcaa
    11401 aagtcatcgc aaacataaaa attttgactt attgagtttt gaaggacatc cttctatcaa
    11461 tgatgtggaa aaatatcggg atggcatatt aaaagtgtca aaagacaact ctgtagatct
    11521 agctgaaaat gaattctatt accatgagat catcggtctg catgtattag aagatggaac
    11581 tgagttaggt aaagtaaaag aaatcttgtc accaggtgcc aatgatgttt gggtcgttca
    11641 acgtccgaaa aaagctgata tattgcttcc atatatcgct tctgtcgtca aagaagtcga
    11701 tttagaagct ggagtggtcc gtgtagaaat tccagaagga ctgattgacg atgaagattg
    11761 atgtattgac tttatttcca agaatgtttg aaggtcctat gggggaatcc atcatcggta
    11821 aggctgtaga taaaggatta ttagatatca atatctctaa cttccgcgat tattcagata
    11881 acaaacatca gacagtagat gattatccat acggcggtgg agcaggtatg ctgctcaaag
    11941 tccagcccat ctatgataac atccaagcca ttgaaaaagc tgcaccggat gtcaaaaaaa
    12001 gagtaattct tcttgaccca gctggtaaac gattcgatca gaaaatggca gaagaatttt
    12061 cacaagaaga acacttagta ttcatttgtg gtcattatga gggatatgat gaacgtatcc
    12121 gcacattagt gacagatgaa gtttccttag gagattatgt ccttactggg ggagaattag
    12181 gtgcgatggt catgatcgat gcaacagttc ggcttttgcc agatgtgtta gggaatcaga
    12241 cttcagctca aacggattct tattcaaccg gtttattgga acatccccaa tatactcgcc
    12301 cggcagaata taaagggatg aaagtaccag aagtattgac aaatggaaat cataaattga
    12361 ttgaagaatg gcaattaaaa gaatcactaa gaaggaccta tcaacgtcgg cctgatcttt
    12421 tggaaacact tgaatggaca cctcaaatga cgaaattttt agaagaaatc aagaaagaag
    12481 aacaagaaaa aacagcagat gaagccaagt gactttttct aaaatcttct ttacagtagg
    12541 ttgataatat gttagtattt tatggtgagt gcaaaagcac ttaactatta cgatattccg
    12601 ctgtgagaaa agctcataag aatatttgga ataaggagaa gaaaaccatg aatccattaa
    12661 tcgaagaatt aacaaaagaa caattacgtt ctgacatccc agcgttccgc cctggtgaca
    12721 ctgtgcgtgt tcacgcaaaa gttgttgaag gtactcgtga acgtatccag ttatttgaag
    12781 gtgttgttat caaacgccgc ggtgctggaa tcagcgaaac ttatacagta cgtaaagttt
    12841 ctaacggagt gggcgttgaa cgtacattcc cattgcatac accacgtgtt gcaaaaatcg
    12901 aagtagttcg ctacggtaaa gtacgtcgtg caaaattgta ctacctacgt gcattacacg
    12961 gaaaagctgc tcgtatcaaa gaaatcagaa gataaacacg gaaaacttcc ttggaaatct
    13021 gaaatttgtg aaaagtcctt gtatatcaag ggctttttct tttttctcta tcacagtttt
    13081 aagccatttt tggctgtttt ggaccatttt tcaatcatat tcccttaaaa attgtcctag
    13141 attgtccgac attgactatc agtgtcgtca aaatagggca aaatttagta gtcagcttga
    13201 cgacaaatat aatacgaaaa ataccaaaac atttaccgaa tttagcaact tttgaaccca
    13261 agtttctcaa agggtcagct attagcaaaa aagacaaaac atgtactttt ctactaaaaa
    13321 gttgatgtga taggcttcta tctaaataac tattaggagt ttttatcgtg aagcaaaatg
    13381 atggacgtat catttggaaa aatcaaagtg agttaaaact gattttaaca attaatgaat
    13441 tcatcgaaaa acacggaatt acatctagcc gtcaatacca gaaaaagcta tcagaaaatc
    13501 caaattctgc accaagtatg tggttcatta acaaaaaata tggatcatgg gagaatttat
    13561 tgattagtat aggacgagaa aatactgggt atggaaaatg ggctagaatg tcagaacaag
    13621 aattattgga aatagtagaa gcctttatta agtgcgagaa gataacctct caacgaatgt
    13681 acgaacaaaa atcagtaggg aagaatattc cttcacttag taccattaaa aagatgttag
    13741 gagatatacg tccacttttt aaagaaaaaa atgatggatc tcgatttact gatttcgaac
    13801 tgctgttaga actaaaaaat gaaataatcc gattaaaact acaggatgat ttatcaatga
    13861 caaagtttcg aaaactagtt caatccccaa aactaccatc agttgataca attatgaaaa
    13921 gaacgaacaa aaattgggag gaattgatgg cagagattgg atttgattat cgaagaatca
    13981 aaatttataa gcagagaaac aacctatcca agacaaagaa aactaaatag tatcactcta
    14041 aatcagacgt tcaaaattaa aatttggacg tcttttttat tacccaaaaa cgaaaggaga
    14101 tttattttat gaaaaagcca agatttaaga attggcgttt gctcgcaaca ctgagtctat
    14161 tatgccaaac aattggtgga tcgcttggcc caacgattgc ctttgctgat gaaattactc
    14221 atccacaaac ggtaactgtg gaattggatt tggctcacca gtatgctgtc gaaggtacat
    14281 ttagcgatgg tcgtcccatg tcagaagtta ccgttccgca ctatgcagtt tacaatggtg
    14341 tgaagcaaga tattttctgt attgagccag gggtgccgat ttacaatgag ttcactcctg
    14401 gttatgagaa aaatccattg cctgatatgt cggagaaagc gaaattagtt tccgttttat
    14461 ggaaggaagc tggtacggat gtggatacac atattgtggc ccagaagatg atttggcaag
    14521 aagttaatgg ctacacgctt cactcaatta aacgttctga tggtagtgca gtaaatatcg
    14581 cagccattga gtcaaaaatc aatcaagcca ttgcggatta tcaaaagaaa ccaagcttcc
    14641 ataactccac agtgaaaacc gtgttaggtc aatcgactac tgtgacagat acgaacggct
    14701 tgaatttatc ggagtttgat gaagttgtcg agaatatcgc aaatattgat tatcgtgtga
    14761 acggcaatca actagtgatt actccaaatg ccaattcaaa agagagtggt gaattaaccc
    14821 taaagaagtc agctaataca ggaacaccgg tagcttataa aatggctggt caacaaactt
    14881 tgatggcggg ggcaattgat aagcccaata cctacacaat caaaattgat gtggaaactg
    14941 agggttcttt gaagattaaa aaagtcgata aagaaacagg aaatgttgta ccgggaaccg
    15001 ttttccattt agactttgga aaaacattac ctgcaaaaga cgtgaccacc gataaagaag
    15061 gcattgcgac attggatgag attcctcatg gcgcgaaagt aaccattact gaaaaatcag
    15121 tgccagctcc ttatacgatt gacactacac caatcaccgc aaccattaaa tctggtgaga
    15181 ctatttctgt gacttcaaaa aatactcgcg aaaaaggtca aatcattttg aataaaatgg
    15241 gggtggaaac aggaactgat ctttggaacg acaaatactc attagccgga aatacgtttg
    15301 ccattcgcaa agacagtcca accggtgaaa ttgtccaaga aatgaccacg gatgaaaaag
    15361 gtcatgcgga aacaccaaaa gagattgcca atgcgttgga attgggaacc tattatgtga
    15421 ccgaaaccaa agctagtaat ggctttgtga atacctttaa accagtaaaa gtcgaattga
    15481 actatgtcaa tcaaaccgtg gctcttgtta ccagtaacgt aaaagggcaa aaccaagaaa
    15541 tcactggtga aaccactttg acaaaagaag acaaagatac cggtaatgaa actcaaggta
    15601 aagctgagtt taaaggagct gaatatactc tctttactgc aaaagatggt caagcggtca
    15661 aatggagtga ggcttttaaa ccagagttag tgaagggaac gaaagcttct gatgaaacgg
    15721 tgactttgac tttagatgaa aagaatcaag ttgctgttaa acacttagcg attaatgagt
    15781 attactggca agaaaccaaa gcacctgaag gatatacctt ggatgaaaca aagtaccctg
    15841 tttccatcaa aaaggtggat gataacgaaa aaaatgccgt gattacccga gatgttacgg
    15901 caaaagaaca agtcattcgc tttggctttg atttctttaa atttgctgga tcagctgctg
    15961 ggactgccga aactggcttc aatgatctga cctttaaagt atcgccattg gaaggaacca
    16021 gtgagattac aggtgccgaa gatgaagcaa ttacagctta taacgagcaa ctaggttttg
    16081 atggctatgg caagtttgaa aatcttcctt atggggatta tttacttgaa gaagtagagg
    16141 ctccagaagg atttcaaaaa attacgccat tagaaatccg ttctactttt aaagaaaata
    16201 aagcggatta cactaagagt gaatacattt ttacgattac cgaaaaagga caaaaacaac
    16261 caattaaaac ggtgaccgtt ccttacgaga aactgacgaa taaagcattt tctgttagct
    16321 tgaatcgttt gatgctctat gatttacctg aagaagaaga tagcttaact tctcttggga
    16381 cttggaaaga cggaggcaaa gaattgacag accttgattc taccgagcta gttgataaat
    16441 tgagctataa cttgcatgaa atcaaagaag actggtatgt ggtagcgcaa gccattgatg
    16501 tggaagcgac aaaagctgcc caagaaaaag atgaaaaagc caaaccagtg gtaattgccg
    16561 aaacaaccgc aacgttggcg aataaagaga aaacaggaac ttggaaaatt ttgcataaat
    16621 taaccgcaga acaagttttg gataaaacca tcgtcttatt caactatgtg tatgaaaaca
    16681 agaaacccta tgaagcaggt gatgatccag tagcgaaaga tgctagcttg aacaatcaag
    16741 cccaaactgt caattgtacg gtggaacgcc atgtttccat ccaaacaaaa gcccacctag
    16801 aagatggttc gcaaaccttt actcatgggg atgtggtgga tatgttcgat gatgtgtcga
    16861 ttacccatga tgtactggat ggctcaaaag aagcttttga aacaattctg tatgcattac
    16921 ttccggataa tacgaccaaa gaaatttgga aatctggcaa aattgattat gaagtgaatg
    16981 acaaagaatt cactaaaacc gtacttgcgg aaaaagtgga cacaagtaaa tatccagaag
    17041 gtacaagttt taccttcaaa gaaattaact atggcaaaga cggaaacatc aatgggaaac
    17101 acaatgagga tctaaaagaa aaaactcaaa ctttaacacc taaaaaagtt ccgacaacac
    17161 caagtgcacc agaacaaccg gaaataccaa ctgttccaag tgactctcaa gaatctagtc
    17221 ctacagtaaa gacattccca caaacagggg agaaaaattc taatgttctg ctgtttattg
    17281 ggtttacctt gatctttgcg actgctgggt attatttctg gaatcgccga aactaaggtg
    17341 atgtgatgaa acaactaaat aggaaaaacc aacgtgcgcg accgcctcct aaaaaaagtg
    17401 gtcgcgctat ttttgtatcc aaaactaaaa atgaaaagag gaaaagaaga tggaattgaa
    17461 atttgttgtg ccagatatgg ccgaaacctt tggaaagata aggtatgccg gcgaaggcga
    17521 agttttaact gaaggatatg ggcggaatac tacagtaatt ggtcgtagtt atcatttgta
    17581 ttccagtaag caacgagccg atgatattga agtggtggta gctgcggaag ccggcgaaaa
    17641 ggattttgat caagatcaac cactaaaagc cgtgaatccc catttggttg ccaaaggcta
    17701 tgagattgag aatcgtgggt ttaccgacta cgtgttgtat gtcgatgatt tagtgaaagc
    17761 ataggaggaa aagaagatga gattaacaga aggtattgtt gtagattcag gactaacgtt
    17821 tgggaaatta cgattttccg cattacgccg agaagtacgg aagcaaaatg aggatggaac
    17881 ggttagtaac gaggtaaaag aacggactta taatttgaaa tcctctgcgc aaggtcgaat
    17941 gatccaagtt agtatcccag caaatgtacc cttacgcgag tttgcctatg acgcagaggt
    18001 agagttggtc aatccaatca tggatacggt cgccaattat gttttccgag aaggaactac
    18061 tgtcaattgg ttcattaagg ccgatgattt agtcttgaaa cgacaaccag atcagggaaa
    18121 ttctacaaac caaaatgaag gaaagaaata ggtgaagcgt atggaaatta atgttgaaca
    18181 tattttagat tgtctcgatc aatatggaaa aggtgagcta acggaggaac aactcactaa
    18241 agcattaacc tatgatgaaa aaatgtttct gattatgcat caagggttac tggaagtagg
    18301 taacgatgtc gaagaagatt ttgatgtact gaattggtta ggggaagaag agtccttctt
    18361 tatggttatc gaagtaaatg aaagtctatg tcgagaagcc gaaaccgtat tggaagaaat
    18421 tggtgtggaa atgccggatg ccattgaagt ttttttaaag caactagtgg aaacgaaaca
    18481 actccctata gcagtaaatg actagcataa ctgcttgaaa ttggatcaat gaaatcctat
    18541 gaagcttttt tcgattggag gtggaaacca taaaaatgta caaagggcat cgtatacggg
    18601 caggagatca gcacttggtt tatcactttg ttcttggctg gctactcgct ctgttcatcg
    18661 gttggatgag cgtcttttat tttcaagagc ttagacaatt tgatatttct aagctatcac
    18721 tttctactat agaaatcgtt cgttctataa aagatttaat ctatttgcta ggaagtctcg
    18781 ttctttcagg aagcacgatg ttgctttata tacacttttt tcaggatcat tggcgcagtt
    18841 tgtggcatcg acaaaagcta gcccggatga ttctagaaaa tcattggtac gaagtaaaac
    18901 aaactcagag tgaaggattt ttcaaagacc tcaatagtag tcgaaccaaa gagacaatca
    18961 gttacttccc caaaatctat taccgtatga aggatggttt actttctatt cgcgttcaaa
    19021 tttcactggg aaaatatcaa gatcagcttt taaagctgga aaagaagtta gaaagtggtc
    19081 tatattgtga actagtagaa aaggaactca aagactccta tgtggagtac actttactgt
    19141 atgatataat tgccaatcga attgggatag acgaagtagt ggcagaaagt ggggctttgc
    19201 gattgatgaa aaatcaagta tgggcttatg attctttacc tcatatgtta atcgctggcg
    19261 gcacaggtgg tgggaagact tactttttac tcactatcat cgaggcttta ttaaaatctg
    19321 atgccgagct ttttgttctt gatcccaaaa atgcggactt agccgattta ggtacggtaa
    19381 tgcctcatgt ctattcccaa aaggaggaaa tttctgcttg tgtggaagat ttctatgagc
    19441 gcatgatgac tcgtagcaag gcaatgaaag aaatgcccaa ctacaaaaca ggagagaatt
    19501 atgcgtttct tggacttcca ccaaactttt taatctttga tgaatacgtg gtttatatgg
    19561 aaatgttaac gacgaaggaa agtgcggtga ttttgaataa gctcaaacaa atcgtgatgt
    19621 taggtcgtca atctggtttc tttctgattc tagcttgtca aagaccggat gcgaaatatt
    19681 taggagacgg gattcgcgat caatttaatt tccgggtggc tttgggtcgt atgagtgaac
    19741 tgggatattc catgatgttt ggcgaggttg ataaaaaatt ctttatgaag cgtatcaaag
    19801 gtcgaggcta tgtagatacg ggagggagtg tgattagtga gttttatacg ccacttgtac
    19861 caaaaggata tgatttctta agggaaatta gcgacattgg tggattaaac gttaatacgg
    19921 aaggataaaa taatagtatg tagcctagga gtgtcaagaa tcctgggctt tttttacgag
    19981 gtgatttatg acatttttag atttattcgc tgggattggt ggcttttgct taggtatgga
    20041 acaagcgggt caccagtgta tcggcttttg tgaaattgat gattttgctc gccagagtta
    20101 taaggcaatc catgatacaa gtaaggaggt ggaaatgcat gacatcacaa gtgtatcaga
    20161 cgagtttatt caatctctcg gaccagtgga tatcctttgc ggtggatttc cgtgccaagc
    20221 tttttcaatt gcgggaaagc ggcaaggatt ttccgatact cgaggtactt tattctttga
    20281 aatcgctcgg ttcgccgcta ttctccaacc taagttttta ttccttgaga acgtccgggg
    20341 attactcaat cacgaaggag gggctacgtt cgagacgatc ctccgaacgc tggatggatt
    20401 ggggtatgat gtggaatggc aagtgcttaa ctcaaaggcc tacgttcccc aaaaccgtga
    20461 gcggatcttc cttatcggac attctcgaga cgcatgtacc gaacaagtat ttcctatcat
    20521 tggatcgtct ccaacatctg atcaaaacat cagaaactta ttaaatatca acccttccaa
    20581 tcgaggaatg gggggacaag tctatgggtc agatgacgta gcgcctacct tgaccggtga
    20641 tgaaggaatc aaaatcgcat tgccggtaga tgatggaatt tctgtagcgg gtatgttact
    20701 gggaaatttt gaacaaggca atcgggttta tgagataact ggaacagcgc ctactttgtc
    20761 aacgaaacaa ggcggaacga agatcatgct tcggaaaaac gaaacagaat atcaagaggt
    20821 gaagccaggg aacagtgtga acctggcttt tcctaattcc acaagtcgtc gaggccgtct
    20881 gggaaaacaa agtgtgcata ccttattaac aggagaccaa caagcagtcg tcacggatca
    20941 gtatcaaatt cgaaagttaa cacctaggga gtgctggcgg cttcagggct ttccggactg
    21001 ggcttttgat cgagcttctc aagtcaattc agatagtcag ttgtataagc aggctggaaa
    21061 ttctgtaaca gttccggtca tttttgatat tgctagaaga ttaaaggagg taaaaacaga
    21121 tgatttatga tgagttgatt ggggaatcta ctgggtgatt ggcaagattc agtcagatcc
    21181 ggaattggaa gaagaactgt accggctcaa ttttgatatt cgcaaaaacg gggtgaaagt
    21241 ccctgatgat ccgtatgtaa ttgatgagga aacggatgct cgaatggagc tgaatcaagt
    21301 catcagtgaa ttggaacgaa ttgcggactt tgctaaagaa cctgatatcc gccaatactt
    21361 gtttgagata aaagcagagt tggaaattga gggtattacc gcggagtaac ggccaaataa
    21421 accactgata ggcactgacc gcgggggatt tgcgaagcag aaatcctccg tggtgctgtg
    21481 cctgtttatg gacggcgtta gccggccatg atgtctcacc ccccgtatct aacagggggg
    21541 tacaaaaaca caaaaaataa gcaagcaacg ataaggaatg gctgtcctat caaggataat
    21601 aagcaatttg tgtagatgtt aactgatttg aaaaagttaa caccttaaat ttggaggtga
    21661 gaacttggca caaaggaatt tagattatcg gctattaaaa gaccggcgta atgaatatgg
    21721 cgtttcacaa aataaattag ctacgacttg tggacttagt cgcccgtact taaatcagat
    21781 agaaaatggt ggcgtaaccg catcgacaaa aaccatgagg aaaatttttg accaactgga
    21841 aagtttcaat cccgagttac ctttaacgtt actgtttgac tatgtaagga ttcgctttcc
    21901 cacaacggat gcgaggaaaa tcattcaaga gattctccat ttgaaatttg attatatgct
    21961 ccacgaagat tacgcctttt actcctatca agaacaatat gttatgggag atattgtggt
    22021 gatgttgtca catgaagaag ataaaggcgt ccttttagaa ttaaagggtc gtggttgtcg
    22081 gcagtttgaa acttttttac tcgcccaaaa gcgtagctgg tatgactttt tcgaagattg
    22141 tctaaaagcc ggtggcgtga tgaaacgctt agacctggca atcaatgatc gagttggcct
    22201 gttagatatt cctgatttaa cgaaaaaatg tcagaaggaa gaatgtatct ccttgtttcg
    22261 taccttcaaa agctatcgtt ccggggaact gttgaaacct gatgataaag atggtatggg
    22321 caatactttg tatattggca gtcttaagag tgaggtctat ttctgtttgt acgaaaaaga
    22381 ctatgagcaa tatatcaagt tagggattcc tttagaccag accgaaacga aaaatcgttt
    22441 tgaaatccga ctgaaaaatg atcgagctta tcatgcaatt caagatttgt taaaaggtcg
    22501 cagtattgaa agtaccacat tttccattat taaccggtac ttgcgatttg cggataaggt
    22561 ggaaggcaaa aggcgaacta actggccctt gaatgaacaa tgggggcgct tcattggacg
    22621 gaatcagaag gaaattcaat taacttctga accgaagcct tataccattg aacgaacgtt
    22681 gaactggctt ggacgacaag tcgcccctac gtggaagatg gccaaggagt tggatcggtt
    22741 gaatcagaca acgtacattc aggatatggt aaataatact cgactatcag accggcacaa
    22801 aaagattttg gagcaacaaa gtatggcaat tgaaaatttg attatatgaa aagaggaatc
    22861 gtgatggaaa ttgtgaaaga tattttattg gtgtttggtg gcagtatgct tggtgttact
    22921 gtgatgtgct tgatgcatgc aagtgcagcg gcggaccgag caatggaaaa gaaaggaaag
    22981 tgatgaaatg aatttcggtc aaaattt
//
LOCUS       DBBGSP010000048        22132 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000048 DBBGSP010000000
VERSION     DBBGSP010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.048"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..523
                     /locus_tag="ACIZE9_002152"
     CDS             <1..523
                     /locus_tag="ACIZE9_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HGC6093998.1"
                     /translation="GGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGIVA
                     NCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIFGS
                     LIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILTVL
                     LLPLFFQPFAGLF"
     gene            523..2109
                     /locus_tag="ACIZE9_002153"
     CDS             523..2109
                     /locus_tag="ACIZE9_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6093999.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            2128..2349
                     /locus_tag="ACIZE9_002154"
     CDS             2128..2349
                     /locus_tag="ACIZE9_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGC6094000.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            2346..3107
                     /locus_tag="ACIZE9_002155"
     CDS             2346..3107
                     /locus_tag="ACIZE9_002155"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGC6094001.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            3487..3996
                     /locus_tag="ACIZE9_002156"
     CDS             3487..3996
                     /locus_tag="ACIZE9_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGC6094002.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(4071..4610)
                     /locus_tag="ACIZE9_002157"
     CDS             complement(4071..4610)
                     /locus_tag="ACIZE9_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGC6094003.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(4750..5361)
                     /gene="rpsD"
                     /locus_tag="ACIZE9_002158"
     CDS             complement(4750..5361)
                     /gene="rpsD"
                     /locus_tag="ACIZE9_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGC6094004.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            5623..6474
                     /locus_tag="ACIZE9_002159"
     CDS             5623..6474
                     /locus_tag="ACIZE9_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGC6094005.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            6502..7137
                     /locus_tag="ACIZE9_002160"
     CDS             6502..7137
                     /locus_tag="ACIZE9_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HGC6094006.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            7157..7930
                     /locus_tag="ACIZE9_002161"
     CDS             7157..7930
                     /locus_tag="ACIZE9_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6094007.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            8338..9135
                     /locus_tag="ACIZE9_002162"
     CDS             8338..9135
                     /locus_tag="ACIZE9_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HGC6094008.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            9113..9526
                     /locus_tag="ACIZE9_002163"
     CDS             9113..9526
                     /locus_tag="ACIZE9_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HGC6094009.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            9510..12155
                     /gene="mutS"
                     /locus_tag="ACIZE9_002164"
     CDS             9510..12155
                     /gene="mutS"
                     /locus_tag="ACIZE9_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGC6094010.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            12173..14281
                     /gene="mutL"
                     /locus_tag="ACIZE9_002165"
     CDS             12173..14281
                     /gene="mutL"
                     /locus_tag="ACIZE9_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGC6094011.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            14303..14863
                     /locus_tag="ACIZE9_002166"
     CDS             14303..14863
                     /locus_tag="ACIZE9_002166"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HGC6094012.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(14948..16936)
                     /gene="treP"
                     /locus_tag="ACIZE9_002167"
     CDS             complement(14948..16936)
                     /gene="treP"
                     /locus_tag="ACIZE9_002167"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGC6094013.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            17159..17872
                     /gene="treR"
                     /locus_tag="ACIZE9_002168"
     CDS             17159..17872
                     /gene="treR"
                     /locus_tag="ACIZE9_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGC6094014.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            17949..18395
                     /gene="msrB"
                     /locus_tag="ACIZE9_002169"
     CDS             17949..18395
                     /gene="msrB"
                     /locus_tag="ACIZE9_002169"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGC6094015.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            18565..19167
                     /gene="ruvA"
                     /locus_tag="ACIZE9_002170"
     CDS             18565..19167
                     /gene="ruvA"
                     /locus_tag="ACIZE9_002170"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGC6094016.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            19180..20181
                     /gene="ruvB"
                     /locus_tag="ACIZE9_002171"
     CDS             19180..20181
                     /gene="ruvB"
                     /locus_tag="ACIZE9_002171"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGC6094017.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            20210..20788
                     /locus_tag="ACIZE9_002172"
     CDS             20210..20788
                     /locus_tag="ACIZE9_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC6094018.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            20840..21322
                     /locus_tag="ACIZE9_002173"
     CDS             20840..21322
                     /locus_tag="ACIZE9_002173"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGC6094019.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            21439..21813
                     /locus_tag="ACIZE9_002174"
     CDS             21439..21813
                     /locus_tag="ACIZE9_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094020.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(21926..>22132)
                     /locus_tag="ACIZE9_002175"
     CDS             complement(21926..>22132)
                     /locus_tag="ACIZE9_002175"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094021.1"
                     /translation="NLTTFENFRHKIFTTNDYYISIPTNNPNNTFSFLTPYPASSPAS
                     RTFFYQKNLYHPIDSTNQPNAVML"
BASE COUNT         7237 a         3991 c         4791 g         6113 t
ORIGIN      
        1 cgggggcaat tttttgacta tgctgattac tcctgcgaca gtggcacttg ccatccctct
       61 ttataaaaac ttccgtttac tgaaagagaa tttttatcct gtaatggctg cgattttagc
      121 aggaatagtc gcaaattgct tggttagtgt agggttcggt tacttcttct ctcttcataa
      181 agagatggtg atctcattac tacctaaatc tgtaacgacg gctatttctg tcgatttatc
      241 tcatacgatg ggcggggtga atgccgtgac acttgctatt gttgtctcta caggtatttt
      301 tggttcgctg atcgccactc atattttccg cctattcaag atcgaaagtc cagttgctcg
      361 cggtgtggcg ttaggaagta cttctcatgc tattggtaca gcaaaagcaa tcgagattgg
      421 tgaaatagaa ggaatcattt ccggacttgc gatatgcgtc aacggaatat tgaccgtttt
      481 attgctaccg ttattctttc agccttttgc tggcttgttt tgatgcgaaa accactattt
      541 tatgctacaa taaccaaaac gttcgagcat aaaaaaggag ggaaagacgt gtatttgtct
      601 tccgagtatc ttaaacaatt tgataaagat ctatattata agattctcct cctagaaagt
      661 tttgaggatc aagcttggca taccgctgca caattagcgc aagttgttca gctggatgcc
      721 cgcagcgtgt cgaaatacct gaacgagctg tctaaaaact atcagcagtt tagcggtaag
      781 acacaccctt tgtttacaaa aaatcaccgt tctggttata acttttatga tacgctcgat
      841 tcaattgaac atgagcgttt tttgatctat ctcgtgcaaa gtacgctgaa attccagttg
      901 ctgcacgaca ttttttttga agaattccat acaatgtacc aatttgcgca aaagcattac
      961 attagtgaat ctactgctca tcgaaaaatc aatgaatgga aacagcaact gcaaacttac
     1021 ggaattcggc tgcaacgagg tacatatatc gctcaaggcg aagaagaaat cattcgactt
     1081 tacttgcata tgacattctg gcagttgttt cgagggaaaa tctggccatt tgaaacgatt
     1141 tctcaaatgg acgtaaagaa tatggcagaa catatcatgg ctttttttaa tgttcgtctg
     1201 aacgagatca aaaaaagacg attggaatat atgctaggtg cctttttttt aagaaaatca
     1261 cagaagcatt atgttgtatt gaatgagaaa aaaagacggc tgatttctga caatctgttg
     1321 ttccagcgat tttgccaggt catggagccg gtatttccta attattttca agtagaagac
     1381 gagttaggcg cattatttct tgtactgatg actcgtgaag aatattatag tgatcctaag
     1441 atacggaaga aaatttttga ttttcatcaa caagcaaaaa caccgccctt tacagccctt
     1501 tcagaagcaa aagccgctct ttctctttat caggaagagc aggggctgcc agcagaaaat
     1561 ctaaccttcg aggcagaaaa ctatttattc agcagtcatt ttttcgccta tctttttcct
     1621 aatgcgaaag aaacgattga tggcaatagt agtgatttta ttaatcattt agttattgaa
     1681 aacaaggaat tgaaacaatg gctcgtacat ttttttgaaa gtagacacaa acatcccaat
     1741 catctggcat ttaaaaatca tgcgtttttg atggggcggt atctgactgt gtttaaaaca
     1801 ttaggagcct ttactccaca gcttccaaag atcacgatcc ttttaatgac agatttccca
     1861 ttatttgaag agcaactgtt agaggaggga ttacggacat ttttccgtaa tgagtatcag
     1921 ctgatttttc tgccaacaga ttatcggggg agagaagttg atcttctgat ttcgacaagt
     1981 aaagtccacc gcaaaccatg ggcggatctt gactatttta ttgtgactga agaactaaaa
     2041 ttaattgatt acatccaact atctcaaaaa tttgaaatga ttcaaaaaca aaaactatta
     2101 aaacaataac aaagaaggag aaaaaagatg acatttgaag aaattttacc agaattgaaa
     2161 aaaggtgcaa agattattcg taaaggatgg agtggatttg aactttatgt tgttctcgta
     2221 tccgatgatg aatttgatgg ctgtccggtg acgccgtact tattgatcaa aacaagtgac
     2281 gaaggttttt ccagcttcgc tcctacagtt tgtgatattt tagcagatga ttgggcgatc
     2341 gtagaatgaa aaaccagtat ccagatctag ctaaacaggt tgtatttatc acaggagctg
     2401 cttctggaat tggtgctgcg caagcccgag cgtttcttga acaagatgct tttgtatttg
     2461 gattagatca aaagttcggt aaaatggaag aaatttcttt gcgatttcct gaaacttttg
     2521 cctacgcact aggtgatgtt cgacaaatga aagaactcca acaagcggta tcgaaatgcc
     2581 aaaatcattt tggtgaagtt acgattttac tgaatacagc ggggatattg gatgcctaca
     2641 aacccttgat ggaaactgac gaatcgctgt gggatctgat ttatgagacg aatgtgaaaa
     2701 gcatgtatca gctgacaaaa atcatccttc ctgatatgat ccgccaaaaa agcggaacga
     2761 tcatcaatat ggcttcgatt gctggcttga ttgctggtgg aggtgggatc gcttatacaa
     2821 gcgcgaaaca tgcgattgtc ggatttacca aacaactcgc tctggattac gcaggacagg
     2881 gtatccgagt aaaaggaatt gctccaggag ccatccaaac accaatgaat gcggctgatt
     2941 ttgaagggaa aggtgagatg gcagagtggg tggcaaatga aacaccagtc aagcgatggg
     3001 cacagccgga agaagtagct gagctgacgt tatttcttgc ctctcctcaa gcaagctaca
     3061 tacaaggaac gatcatccca atcgacggcg gatggttgtt aaaataacct tgtgtttttt
     3121 tcaagcttct gtatgataaa actaaagaga gaaacaacgg ttgatgataa aaaaagtcga
     3181 tgactgttcc cgacattcga tgccgaacag ccagttcaaa aaattctttt taataatcgt
     3241 taatattcga aactaagcgg cttttcacga cctcttgata taaacgatat tcaaaagctt
     3301 gcaactgcgg taacaagtcc agccaaatga aaaatataag gagctatttt tatttgacca
     3361 ttcttattac ttgttgcagg gcagcttttt cactaccttc tgcgacactt cagttggaat
     3421 tttcttccca tcctttggtc gcggtcatta ccaagataaa attatcttgc aaaggagaaa
     3481 tagaacatgg aaaaaaataa tacccgttca gccaaacgct ggacaacgac agatgtgact
     3541 cggatggcgc tagtcactgg tttatatgtg gcagtgacgc tggttttgtc tgtctttagc
     3601 tttggagtga ttcagattcg tctctcggag atgttcaact atctgtcctt gtataacaaa
     3661 agatacatcg tcgcggtaac agcgggagta gctttggcta atattgcttc tcctcttgga
     3721 ctgatagatg ttgcagtagg aagcgtcagc acgctgcttg tattgcttat caactataaa
     3781 atcactagtc gcatcaaaaa catgaaaatc aaaatggccg tgacagcatg cgtatttgct
     3841 ttttccatgt ttacagtagc tggtcagcta acgattttat atcaactacc ttttttcttg
     3901 aattggtggg tgattgcttt aggagaattg gcatcaatga ttgtcggtgg gataattatt
     3961 tattggatcg gtaaaaaagt ggatttgtca aaataaagat ctgtttaatt taaaataggg
     4021 cagcatggaa gagactgaat gttgagtctt cttccatgct gcttttttga ttaatttgta
     4081 tgaagaaatc gatttagccg ttttttcatc aagataccga tataagctgc tccagttgcc
     4141 ttgattgctt ccggcagtaa aaacggcagt agtccactgg caaatgcagt tgtaaaagta
     4201 agatcaccac ttattttcag ccagatcgtt ccgcagatca atgcagcaag agagcccatt
     4261 agattggcaa agattgcata taagtaatga gcatccgttc tttcgatcat ccaaccagtt
     4321 atccacgttt gtaagagaaa tccaatcaaa tatccgccag ttggcccaaa taaaacagct
     4381 atacctccag tcatccctga aaatacagga agaccaatca agccaagtaa aagataaact
     4441 ccaacagata tcaatcctag ttttcttccg agaaaagttg ctgttaatcc aatagcaaat
     4501 gtttgccctg tcaaaggaac caaaccaaaa ggaatggtca tctgagaaag gacagaaata
     4561 atcgcggcaa attccgcagc aagtatcaat tctttcaatg ttcggttcat aacgccctct
     4621 tttcgttaac ttaatatttt tatttggtta acgaaattgt aaaacaaagt gattactttg
     4681 taaatagaaa atataaaaaa agaccagcta tccaatagat agcggtcttt ttcaagaaag
     4741 cttttgaaat tataagcttt ggttgtagta ttcaacgaca agagcttcgt cgatttctgg
     4801 atatagttcg tcacgttctg gtaaacgagt caatgaacct tccaattttt cagcgtcaaa
     4861 gcttacgaat gctgggcgtc caacagttgc ttctacagct tcttttactg ttacgatgtt
     4921 ttgtgatttt tcacgaactg agatcacttg acccacttct acgtggtatg aagggatatc
     4981 aacgcgtttg ccatcaacta aaatgtgacc atggttaact aattgacgtg cttgacgacg
     5041 agtcgttgca agtcctaaac ggtaaacaac attgtctaaa cgttgttcta gtaagatcat
     5101 gaagttaaca ccatgtttac cttctttgat tttgctagct tttacgaaca agttacggaa
     5161 ttgacgttcg ttcattccgt acatgtgacg aagtttttgt ttttcagtta attgcatgcc
     5221 gtattctgat tgtttgccac ggctattagg tccatgttga cctggtgcgt aagggcgacg
     5281 tgctaattct tttcctgtgc ctgacaatga gatgcctaag cgacgagaaa ttttccatga
     5341 tggtcctgta taacgagaca ttaaaatttc ctccaatgaa tataagtttt tggagtaaaa
     5401 taatccgttg aaaaattcat aatcatatag tttgttcttc aatcttcacc tttgcagccg
     5461 cggttacaca atcgaacccg agacggggca acaaactagg gatgagttat tatttttctg
     5521 ctgcattatt ttacacaaat tacagtatat gatagatcat ccacgaatgt caagataatt
     5581 agtacataaa aacgctttac aaacctaggc tgtctttata aaatgagagg gtatgtgcaa
     5641 atggaaaaaa gcgaaggaag tttaaggaga aaatcaatga atccggtatc accattattt
     5701 gagaaaatcg atgcttcaat tgaaaagaag gcgaatcttt ttgaaaacag cttttcacgt
     5761 tacgctgttc gagcggttct cgcctgtttg tttttgactt taggaacggc tgtggcattt
     5821 gcgatcgcga tgaaggggga agatatcgcg catggtctag gaaagatttt atacgcattt
     5881 atgttcagct ggggtctggt catgattcta tacatgaacg ccgaattagg aacatcgaat
     5941 atgctttata tgaccgtggg tgtttttcgg cagagacttg ctttaagtaa ggcagccaag
     6001 attctatttg cctgtatttt tttcaatatg attggcggta tattatgtgg atttctaatt
     6061 tctatgacta cgccatttca agatttaacg ttggacaact ttatgttaga atcaatagca
     6121 gtaaaactag caaaaccttc agcaacgatt ttggtggaag ggatgtttgc gaatatcgtt
     6181 gtcaataccg ctgtactgat cagcatgcgg atgaaagagg atgtcggaaa agtgatcaca
     6241 gtcgtattca tcattttcat ttttgctttt ttaggatatg aacacgtgat agcgaatttt
     6301 cctgccttta cgcttactta ctttgcttct cacggacaga tggatggaat gacagtcagc
     6361 aatgtgttac ataatttgtt ttttgctttg gcaggaaatt atattggtgg cggtttagta
     6421 atgggactgg gatatgcttg gctgaatcag tcaaaatcat cctatgtgga ctaaaaagtc
     6481 gttcattaaa ggggaagtgc catggaagtt ttagtttttc caaaaaatga ggaaaaagcg
     6541 ttacaaatgg aaaagtacat gaaaaatctt ttttcctttg ctggagtacc taagccggaa
     6601 cgcgctcttt tacaacaacc gttactggat gagagcaaaa atttatctat ttctgaagtt
     6661 ttagcttttg ttcattatta ttatgaacaa atcgaaagag agtatcagta tgtagcgatc
     6721 gatttagtcc agaaaaacat caaacggctt acatttgaag acttagtcgt attgttgcca
     6781 ctagttcaga aaaaagaatg gtgggacagc atcgactctt ggagaaaagt atacagcaca
     6841 tggtgtaaag cctacccaga gcagcgtgaa gaagtctttc aattgtttga aaaaaaggaa
     6901 gatttttggc tacgtcgaat agcaatcacg ttgcaattag gttataaaca gcaaacagac
     6961 acaggactat tgatccgagc aatagacgaa gatcgtcaaa caaaggaatt ctttatccaa
     7021 aaagcaattg gttgggcatt acgcgattat agtaagaccg atgccgattg ggtaaaaaga
     7081 cagctgacaa cagatttgag taagttagct gttcgagagg caagtaagta tttataagaa
     7141 agcgagacga caagagatga gacgcaaatt atttgctttt gatattgatg gaacgttgtt
     7201 agattcaaac aaacaagctt tagatagcac aagagaagca ttggaaaaat tacgcaaagc
     7261 cggtcatctg gtcacgattg ctacagggcg gagccgattt catgcgcaag agatcattcg
     7321 cgatcttgat tttacgaact acattttatg taatggagcg gccggttttt tagaccatga
     7381 acaagtatat aagaatttac tagatcgcga ccagttggat gcgttcgttc aagaagcgca
     7441 tcatgagcag atcgatacag cttttgtcag cttagacaat atcaagcgtt cttcttccaa
     7501 tgatgtaacg gtgatggaag aagcgatgca ttctttcggt gctgtcttgc ctgaattaga
     7561 tcagtttttt gcagaggaac aagaaatata ccaagcgtta gcatttttcg atcaaacata
     7621 tgatgggaag ttctcttcat atgataaaat tcgatttgtc cgctggcatg agaacagtgt
     7681 agatgtcgta cctaaaaatg gttctaaagc agcgacaatt ctgcacttag cagaacaagt
     7741 aggcatccct catgaagaca tcatcagctt tggcgatgga caaaacgacc gtgaaatgtt
     7801 gcgcatgtca ggaattggga tagctatggg gaatgctgtg ccagaagtac aagcagaagc
     7861 taagatggtc actgatacaa acgatcagga tggaatttgg aaggcattga aagagttaag
     7921 cgtgatttaa aagaggttgt gaaaaagctg ttctgcatca agtaataagc ccagccaaac
     7981 aaaaatagct cctcctattt ttcgtttttc tgggcttatt accgcagatg caagctttcg
     8041 aacaccgttt aaggaagagg tcgtgacaga agtggtcagt ttcaagaaat aagaagggat
     8101 ttacgaaaat tgcttctcaa atttttgtaa aattacggct tatttctgaa gaagtagatg
     8161 aaacaacgtt tattcgggaa atgggactgt gacaagatgt ttgtcatagt cccatttttt
     8221 tattttattt ttcaaaacta agaaatacca ggaaagagtt ccttttgttt gaccttttct
     8281 ttcttattga aaacaactat aatatagagt gatgttaaaa gagaagagga atttagtgtg
     8341 cgggtattgt ttattggtga tgtagtaggt tcaatgggac gagagatgat tactgaatat
     8401 cttcctagat tgaagaagaa gtaccgtccg caagtaacga ttgtaaatgg tgagaatgcc
     8461 gcttctggac gtggaatcac agaaaaaatc tataaaaaat ttttgcaaga cggcgtagat
     8521 gtcgtgacga tggggaatca tacgtgggac aaccgcggaa tctttgagtt tgtaaatgaa
     8581 gctaaaaaga tggttcgtcc ggcaaatttt ccggaaggga cgcctggaca agggatggtc
     8641 tttgtcaaag tgaaccaagt cgaactggca gtgatcaaca tgcaggctcg ttcttttatg
     8701 gtggacttgg atgatccttt tcgtaaaatg aatgagctgg tagaagaagc cagaaaacgt
     8761 acgccgatca tttttgtaga ttttcatgga gaaacaacaa gtgaaaaaca agcaatgggc
     8821 tggtttttag atgggaaagt ttcagcagtg gtcggtacac atacacacgt tcagacaaat
     8881 gatgcgcgaa ttttgccaag aggaacagcg tatctgacag acgttgggat gacaggtccc
     8941 tatgatggta ttttgggtat gcgcagagaa cctgtaatcg aaaagtttct gactgcatta
     9001 ccaaaacgtt ttgaagttgt ggaacaaggc cgatcgattt taagcggctg tatcttggaa
     9061 ttggatgata cgacaggtca tgcaaaagaa atccagctga ttcagatcaa cgatgatcga
     9121 ccgttcatgg agtagaaaga gaggcagttt tttgcagcag gagccggaaa ttcaaaaaga
     9181 agtaaggaaa ctgacaaaac ttttaagaga gaatgaaacg atcattcgct acaaagaact
     9241 tgaagaaaag atccagcaaa accagtattt agctgagttg agagaaaaaa tcaaacaagc
     9301 gcaaaaagat gctgttcatt ttgcccacta tgacaaacca gcagcagaaa aagaagcaat
     9361 caaacaagcg gatcaattca tgcaagaatt tgatcagcat ccgcttgttg tagcttatag
     9421 aaaacagctg ttggaagcag atgatctgct tcatcattta acaactatga tacaagaaga
     9481 aatcaatgga caaatagagg aggaaaaaca tgcctcaaaa aactaaaaat actcctatga
     9541 tggaacaata tctaagcatc aaggcccaat accaagatgc ttttttgttc tatcgtttag
     9601 gagactttta tgaactattt tacgaagatg cgatcaaagc gtcacagctt ttggaattaa
     9661 cgttgacgag cagaaatcga aatgcagaag aacctattcc tatgtgcggt gtacctcacc
     9721 atgcagcaca aggatatatc gatgccttga ttgaaaaagg ctataaagta gcgatttgcg
     9781 agcaggtaga agatccaaag acgactaaag ggatggtcaa gcgcgaagtg atccagctag
     9841 tcactcctgg tacagtcatg gacagcaaag gattgtcggc aaaagacaac aattttttaa
     9901 cagctgtagt tagtcaagga aatgaatttg gctttgctta tgccgattta agtacgggag
     9961 aattgaagac ggctcggttg catgatgaag aagctgtttt aaatgaagcc tctgcattgc
    10021 agacaaaaga actcgtatta ggcagtgaga tcactgatac ccttcgtgaa cagctaagcg
    10081 ggcgtttagg gctagtcttt tctcaacaaa atgagatgga agaaaacgcg gaatttagct
    10141 ttttgacaag cgaactagtc gatccgctgg aaaaagaagc aaccggcaaa ctattgactt
    10201 atttatcggt gacacaaaag cggagtttag ctcatatcca aaaagcagta gaataccaac
    10261 cagatcattt tttgaaaatg gattattatt caaaattcaa cctagaatta agccaatcta
    10321 ttcggactgg gaaaaagcac ggcactcttc tatggttgtt agatgaaaca aaaacagcaa
    10381 tgggtggccg tttactaaaa caatggctag accgtccgct tatccaggca aaacaaatta
    10441 aagcaagaca agaaatggtc gcttctttgc tagacagcta ttttgaacgt atcgatttgc
    10501 agtcagcatt aacgaaagtc tatgatctgg aacgcctagc aggtcgagta gctttcggta
    10561 atgtcaatgg gcgagacttg atccagctga aaacttcttt agaacaagtg ccaatgatca
    10621 gagggttgat tgaaggaatc gatcaaggtc aatggcaaag tctgctttca gaaatgcagc
    10681 cgatggacca tctcgtccaa ttgatcgacc aagctatcca agatgatccg ccgttacaaa
    10741 taacggaagg aaacatcatc aaagatggat tcaatgagca gctcgatatg taccgttctg
    10801 ctatgagaaa cggaaagaaa tggttggcag aacttgaagc aaaagagcgt caagaaacag
    10861 gaatcaagaa cttaaaaatc ggatttaacc gcgttttcgg ttattatata gaaattacaa
    10921 aagcaaatct tggaaatgca gaactggaga agtatgaacg aaaacaaact ttagcaaatg
    10981 cagagcgttt catcacacca gaactaaaag aattggagac acaaatcctc gaagcagaag
    11041 aaaaatctgt tgatttagaa tatcagttgt ttttagctgt gagagaagaa gtcaaaaagg
    11101 ctatccagcc gctacaagta cttgcaaaag caatcagtgc agtagatgtg ctacaaagtt
    11161 ttgcaacgat cagcgaacgc tatcagtatg ttcggccaga acttgtcagt gacaagcatc
    11221 agcttctgat caaagacgga cgacatcctg tagtagaaaa agtattagga catcaggaat
    11281 atatccctaa cagcgtagaa atggcagaag acgaaatgat cttgctgatt acaggaccga
    11341 atatgtctgg taaaagtacg tatatgcgac agttggcatt aactgttctg atggcgcaaa
    11401 tgggctgttt cgttccggca aaacaagcag ttttacctat ttttgatcgg atttttaccc
    11461 gaattggtgc aagtgacgac ttaattgctg gacaaagtac ttttatggta gagatgatgg
    11521 aagccaatca agccctgcgt tatgctacgc caaacagttt gattttgttt gacgaactag
    11581 ggcgaggaac agcaacctat gacggaatgg cgttggccca agcaatcatc gaatatatcc
    11641 atcgtcatgt acaagcaaaa acactctttt ctactcatta tcatgaactg acggtacttg
    11701 agaaagaact tccgcagctt aaaaatgtcc atgttggagc cgttgaaaaa gacggagaag
    11761 ttgtcttctt gcataaaatg atggatggac ctgcggataa aagctacggc atacatgtgg
    11821 caaagatcgc aggattgcct tccaatctac tagaacgagc agcagatatc ctgcatacgc
    11881 tagaaaatgg cgataacgga caccatactg ttccagctga agtagaagag aaaactaaaa
    11941 cagccaaaca ggagcaaata aaaccacctg cagaaaaagt aaatcaagac catatacaag
    12001 accgtgtaaa agaagaaaac caacagcttt ctttattcag tgaattatcc gaaaatgaaa
    12061 cagaagtcat tgaatcactg aagcaaataa atttactaga aatgacgcca atggatgcac
    12121 taaacacatt atatgaatta caaaaacaac tgtaggaaga aggcggatat cgatggccaa
    12181 aatccaagaa ttatctgaac gtttagctaa tcagatcgct gcgggagaag tagtggagcg
    12241 accagcttcc gttgtgaaag aattagtgga aaatgcaatt gacgccggca gtactcagat
    12301 tgatatctta gttgaagaag cgggactgcg gacgatccaa gtgattgata acggagaagg
    12361 cattttggca gacgacgtag agaatgcctt caagcggcat gcgacaagta agatccataa
    12421 tcgcgacgat ctttttcgca tacgaacgct gggctttcga ggggaagctt tgccaagtat
    12481 tgcctctgtt tctgaaatga ctctggaaac ggcgaatcag gaagaaaaac aaggcaccta
    12541 tctgtcgctg aaaggcggag aagttattga gcatcgacca gcaccactgc gtcaaggaac
    12601 gaagattacc gtcagcaatc tgtttttcaa tacgccagcc cgcttgaaat acgtgaaaac
    12661 actgcacaca gaattagcga acatcgggga catcgtcaat cgactggcat tgagtcatcc
    12721 atcgattgct tttcgtttag tacatgatgg aaacaaaatg ctggcaactg ctggaaatgg
    12781 cgatctgaaa caaacaattg cgggaatcta cggattatct accgcaaaaa aaatgctgaa
    12841 aatcgaagga aaagatctag attttgagtt atttggctat gtttcattgc ctgaggtgac
    12901 tcgtgccagt aggaattact tatcgacgat catcaatgga cgttttatca agaacttttc
    12961 cttgaataaa gcaatcgttg caggttatgg gtcaaaatta atggtcggtc gtttccctat
    13021 tgctgtattg gaaatcaaaa tggacccgct tttagtagat gtaaatgttc atccgacgaa
    13081 gcaggaagtc cggctgtcga aggaaaaaga actaacagag ctaattagta acgccattca
    13141 aaaagcattg tctcaagaaa atctgattcc aagtgcagcg gataatctac ggtttaagaa
    13201 aaaagtacct gatcagccta aaacagaaca aatcgaaatc gatttgtcct acgcttttga
    13261 agaagaaaaa cctaaaaagc caagtagttt gaattttgat cgacagacag gtaccttttt
    13321 cgtagaagaa ctaaagaaca catttgttga cagaattgtt gataagtctg tggaaaatgt
    13381 tgaaaactat tctggttttt ctgaagaaaa caccacttat ccagaaaaaa cagcgaaaac
    13441 ggtggataag tttggtgaaa atgttgataa ctttgtagaa aaaacagtgg aaaaatctga
    13501 aaagaaagaa tttcccattg tggataacat ggagaaaaca aatgaagaac aagcagataa
    13561 atccgtagaa gaggatgaaa agatttacga ggaagaattg acactccatc ctgaatttga
    13621 tttcactcaa ggaaacgaca aaacattaga acaagccatc aagaaattag aaacggaaaa
    13681 accagtacaa cgttttcctc agttggaata ttttggacag atgcacggaa cgtatctttt
    13741 tgcccaaagt agcgatgggt tgtacatcat tgatcagcat gctgcccaag agcgcattaa
    13801 gtatgaatat ttccgggaaa aaattgggga agtatctgat gatctgcaag aattgcttgt
    13861 tccatttgtg ttagactatc caaacagtga tgctttgaaa ttaaaagagc aaaaacactt
    13921 gctagaagat gcagggattt atttagaaga atttggtcaa aacagcttta ttgtacgggc
    13981 ccatcctact tggtatccca atggagaaga agaatcgatt attcgggaga tgatcgatat
    14041 gctgctgaca actggaagtg tgagtgtaaa aaaattccgt gaagcaacag caatcatgat
    14101 gagttgcaaa cgatcgatta aagccaacca ttatttgaat gaagcacaag cacgtgtgct
    14161 gctgaaggat ctggcacgat gcgaaaatcc tttcaattgt ccccatggcc gtccagtatt
    14221 gattcacttt accaattcgg atatggaaag gatgttcaaa cgaatccaag acccgcatta
    14281 agtcaaagag aagagggaaa acatgaagat tgtattagca tcccaatcac caagaagaaa
    14341 agagttattg gctcatatcg tttcagaatt cgagattgaa cctgctgata tcgatgaaac
    14401 gccatttcca gacgaacagc ccgtcgatta tgttcgtaga atggctgaag aaaaagcacg
    14461 aactgtctgg gaacaagatg aaaaagaaga ccatttagtg attgccagtg acacgactgt
    14521 tgttctcaat caagagatca tgggtaaacc agaagatctg gctgaggctg aattcatgct
    14581 gaaaaaacta agcggggaaa cacatactgt atatacagct gttgttttaa aaacaaagga
    14641 acgagaagaa cggatactag cagaagcaca tgtcactttt tatcctttga cagacgaaga
    14701 gatcaaacgc tacttggaga cgggggatta tgcggataag gcaggggcat acggcatcca
    14761 aaatgctgcg agtgtattcg tcaaagaaat ttctggagat tattacagta tcgtaggatt
    14821 tccgattggt gctgtcaatc aggcactgaa aacattcatt taaacaaaaa agcggactat
    14881 ctgattttcg attgaaaatc catgatagcc cgtttttttt attgaaaaga ttacttatct
    14941 actctgacta agattttact tcagctttac cgactgcttc gcccgggcga acaagtcctg
    15001 attggtcaag agaaagtcct gcaacttttt cattattggt caaagcaaca ataatgtcag
    15061 ttttcttgcc agcttgttct atttctggca aatccatttc agcaatcagg gtctctggtg
    15121 tgacaaggta tccttctttc acgaatacat tgaaaggaac accctttagt tcaacagtat
    15181 ctaatcccat gtgaacaagt acttccagcc cctcattaga aagaatacca atggcatgtt
    15241 ttgtttcaaa gacactcgtc actttaccgt ttactggtgc atagactttg ccgtttgacg
    15301 gttcgacagc ataaccgtca cccatcattt tttgtgagaa aactgggtca tttacttcag
    15361 ttatttcctt gatggtccct gcagcgactg cgaataatgt ttcttttgtt gcaactgccg
    15421 taccagttgc tgaaacaggt tcgaaagact gtggcgttgc tgttgcgcca tttgctgttt
    15481 gaagttgtac atcagcagca ttttcaggaa cagcaggatc aatcttattc aaaattccct
    15541 gacgtctaaa gatgatcgtc aagccaaatg gaatgatgac agcaatgatc attgcgatga
    15601 tgaaaggtac ccatgtttct gcttggatag ctagtattcc tggcaaaccg cctactccga
    15661 tcgcgttagc tcgaacaccc atcaagttag caaacatgcc agctaatcca gagccgacca
    15721 ttgcagcgac gaaaggatag acgtatttca aattgattcc gaacatagca ggttcagtta
    15781 cgcctaagta acaagaaatc attgctggaa tcgagatttg ttcttctttt ttattcccac
    15841 gatgtaagaa gatgatggct aagactgcag agccttgggc gatatttgat aaagcaatca
    15901 tcggccataa attcgttgat ccgaaatctg caatcagctg catatcgatg gcattggtca
    15961 tatggtggag accagtaatc actaaaggag catacaggaa tccgaatacg gcactaaaca
    16021 accagctgat agaagacgtc aatccagtat ttacgatatt tgagatccag cttccgactg
    16081 tccagccgat aggacctaaa ataacgtgtg cagctaaaac agttggtaac aatgaaaaca
    16141 atggaacaaa aatcatcgag atcgactgag ggatatattt gcggaagaag atttctagat
    16201 acgctaacat aaaccctgcc agcatggctg gaataacttg cgcttgataa ccaatcatct
    16261 ggacttgagc aaaaccaaaa tcccaaaatg gaatatctgc tgcggctgtg gaagctacac
    16321 tataagcatt taataattgc ggagaaacta acgtaattcc taaaacgatt cctaatattt
    16381 gtgtagtacc catctttttt gcaatactcc aagtgatacc tactggaaga aaatggaaaa
    16441 ttgcttcacc gggtaaccac aaaaaggcat tgacaccatt ccaaaacttc gagtgttcaa
    16501 cgattgttcc accaagactt tcaaactgga taccttcaag tacatttctg aatccaagga
    16561 tcaatccacc gacaatgatt gcaggaatca gtggtgtaaa gatttctgct aaaacggcaa
    16621 tagcacgttg aacgggatga aggttttgtt ttgcagctgc ttttccttgt tctttggaaa
    16681 ccccttcaac tccagatact gcaacgaagt cgttataaaa agtagaaaca tcgtttccta
    16741 tgatgacttg gaactgtcct gcattcgtga acatcccttt tacgctaggt atatcttcga
    16801 tcgctttttc gtccgctttt cctggatcat tcaggacaaa acgcatacga gtcgcacaat
    16861 gactaactgc agcaatattt tcttttccgc cgatatcatg taacagcttc tcggcatctg
    16921 cttgatattt tgccatatca ataaacccct ttctcttaac ttgtctatgc aagttgtttc
    16981 ttcatttact atactttttt tcggagagaa ttgcaagcgt tttattaaaa agtacgagag
    17041 aaaatgatat cgttttaaaa agcttaaaat aagcttttct taaaaatagg aacattgaaa
    17101 tacaaaaaga gctgtagtat agtgaagaaa tgatggaaga acgagtgagg gaaaaaacat
    17161 gaataagttc aatgaaattt ttttagattt ggaacagaaa attttagcga aagaatatcc
    17221 tccgcattcg cttttaccca gtgagaacca attgatcaaa atttatggtg tttcacgaga
    17281 aacaattaga aaagcgctga atcttttgac tacggaaggt tatattcaaa aaaaacaagg
    17341 aaaaggttcg atcgtactgg atcggaatcg cttcgacttt cctatttctg gattgactag
    17401 ctataaagag ctacaggaga cccaacgtat tccaagtgaa acgatcatcc atacgttaga
    17461 agaaacagaa gtgacaaaag cattgaacga gatcactggc tgggagatcg gtgcgcctgt
    17521 ttggcatttg atacgcgaaa gaaaaatcaa tggcgaagta gttatattag acaccgatta
    17581 tctattaaag gaaatcgttc ctattttaac tccagcacaa gcacaaggat cgatctatga
    17641 atattttgaa aatgagcttt ctttgacgat tgcttacgcg caaaaggaga tcacagtaga
    17701 agaagtaacg gaaatcatga aaacagcgat ggatcttcac gatgacactt atgcagtagt
    17761 agtcagaagc ctcgttcatc tggaagatac ccgctgtttc gagtattctg agtcggttca
    17821 ccgattagat aaattccgtt tcgttgagtt tgcccgacgc cgaaaagtgt aaatagttca
    17881 aaagaaagca aattgttggc atctgtccac tttggcgcta tgataggatc acaaaggggg
    17941 catttttaat ggataaacca ataagaccag aaaaagaaga actgaaagaa aagttatcac
    18001 ccatggctta tgcagtcaca caagaaaatg caacagaacg accatttagc gggaaatatg
    18061 atgattttta cgaaaagggg atctatgtag atatcgtcag cggtgaaccg ttattcagct
    18121 ctgcagaaaa atatgatgca ggttgtggct ggccatcatt cagcaaacca ataacgaaaa
    18181 gacaagtgcg cgaaaaagcc gatttttctc atggcatgca tcgaatagaa gttcgaagca
    18241 aagaagcaga ttctcatctc ggacatgtgt ttaccgatgg accagtagat caaggtggtc
    18301 tacgttactg catcaattct gcctcactga aattcattcc atatgaaaag atggatgaat
    18361 taggttatgg ggaattcaaa tcacttgtag aataatggaa atacacaaag agcggtacaa
    18421 tacggggatt tactcgatcg tccgctcttt ttttattcaa gcgattgcta tttgaaagaa
    18481 acgctcccta gactcctttt ttcacaaggt gaaatgtgct acaataaagg gaacgtatgt
    18541 gtgcaaaaga aagaggacta gaatatgtat gaatatctga caggtgtggt tacctttatc
    18601 aacccctatt acatagtagt agaaaccaat ggtatcggct accagatcgc actaggaaat
    18661 ccttaccgct acagtagcaa actaaatcaa aaaataaaaa tttatgtcca tcaggtaata
    18721 cgtgaagatg cgcatcttct gtatggattt gattcgctag aagaaaagca actgtttttg
    18781 cgattagtaa gtgtttcagg aatcggtccg aaaagtgccc ttgcaatcat ggcaagcgaa
    18841 gaccactccg gtttgattca agcagtagaa tccagtgatg tcacttattt gacgaaattt
    18901 ccaggagtag ggaaaaagac agcacaacaa atgatcttgg atctaaaagg aaaattcggt
    18961 gagctgagta tcgatacacc ttttagtcta tttgatgaag caaacacaaa agacgctaca
    19021 gctctatctg aagcaatgga agctctctcg gctcttggtt acagtgatcg agaaatcaaa
    19081 cgtgtagaaa aacaattaaa agaagtagat aatcagacaa cggatgagta tctacgccaa
    19141 gcactcaagc taatgatgaa aaaataagga ggagaccaaa tgacagatga atacttgtta
    19201 tcaccagaat ctggcgaaaa tgaactgagt ttggaaaaat ctcttcgacc acagctgctt
    19261 tctcaatata tcggacagag aaaagtcaaa caagaacttc agatttacat cgaagctgcc
    19321 agaaatcggg aagaaccttt agatcatgtt ctgttgtacg ggcctcctgg attaggaaaa
    19381 acgacgatgg ccatggtcat tgctaatgag atgaccgtaa atattcgtac gacgagtggc
    19441 cctgctatcg aacgtccggg tgacttagta gcaatcttga atgaactgga agcaggggat
    19501 gtcctgttta tcgatgagat ccatcgatta cctagagtgg tagaagagat gctttattca
    19561 gctatggaag atttctatgt agatatcatg gtaggacaag ggccaaccgc acatccggtt
    19621 catttccctc ttcctccctt tactttgatt ggcgcgacga cacgggcagg tatgctttct
    19681 gcacctttac gagatcgatt tggcatcatt tctcatatgg aatattatga cgaacaggat
    19741 ctgcaggaga tcgttttacg ttcttcggat atttttcaaa cagagatcat tgaagaaggg
    19801 gcattggaaa ttgctcgccg atcacgagga acgcctagaa tcgctaatcg cttgctcaaa
    19861 cgggttcgtg attttgcgca agtccaagga gacgggaaaa tcgatcgtcc tatagcggat
    19921 caggcactta ctttgctaca ggtcgatcag gctggattgg attatgttga ccagaaattg
    19981 ttgcgaacaa tgatcgagtt atatggcggc ggaccagtag ggttaagtac gctttcagta
    20041 aacataggag aagagcgtga gacggtagaa gatatgtatg aaccgtatct gatccaaaaa
    20101 ggatttttaa agcgtacacc tagagggcga attgctactg cttatgccta tgaacatttt
    20161 ggttacgact atcatatatg atttttgctt ttagattgga ggaaaatgaa tgagtgatac
    20221 aacacgtacg aaacaattga tcaaaaacgt attgattgat ttgtgccaaa cgcaatcttt
    20281 tcgaaaaatc agcgtccaaa aaatcgcaaa cgaagcaaaa atcaatcgac aaacatttta
    20341 ttatcatttt acagataaat acgatttgct tcgttgggtc tattgtgagg atgcattgca
    20401 ttatttagat ccacaatgtc tttcacttga taattgggaa gagcaagcat tgaaaatgct
    20461 gaaagcaatt gctgagaaga aagaatttta tgcaaatact gtgctttctg acccagaaat
    20521 tttacaaaaa gagttttctc aactgatcca aaaatcattt atcaagattt ttgaacaaat
    20581 ggatgaagaa agacaacttt ctgcaagaga caaactattt tatgctcgtt ttttttctta
    20641 cggttgcagt ggtgtattag tcaattggat cacgaatgaa tatgaagaaa caccgatgga
    20701 aatcgctatg cagcttttcc gtttagccaa ggatacggaa ttatattctt atcgtcttta
    20761 tgcaaaagaa gagttggaag aacagtaata gaaaaatttt ttgttggaaa agcaataatc
    20821 gctaaaagga gatggggaaa tgacaaaaat tttatttgtt tgtttgggaa atatttgccg
    20881 ttcaccgatg gcagaaggct tgctgagaaa acgaatagca ttagaaggaa gggaagcaga
    20941 attttttgtg gattctgctg ctacaagcac gtatgaagtt ggaaagacac cgcaccctgg
    21001 aacgaaaaaa atattaaacc aagaaaaagt agatatgacg aatatggttg ctcggcaaat
    21061 cacaccccac gattttgaaa cttttgattg gatcattggc atggatcaag aaaatgtaga
    21121 agaactgaaa cgaagagcac cacgctcagc gcaggggaaa atccatttgt ttttaagtag
    21181 cattcctgga aaagaaaaag aaaatgttcc cgacccatac tataccaata actttgatga
    21241 gacatatcac ttgatcacag aaggcctgaa tcattggtgg aatatttgga ttgatgaaaa
    21301 taaaataaca aacaatttgt aaagttaacg ctttcttttt aaggcgatgt tagagcattt
    21361 ccttgttttt ttgtaaaatg ttaggtaaaa taaaattaat taagtaacac tttcttagct
    21421 aaaggaggag tgcattcgat gaacgaagag acagtatcgc caatgaagaa gcttacgaag
    21481 ttagttactc atacttcgta tcaacttttt gattcttttg taaatgacac tgaagaacat
    21541 gctaagaatg tacgattgca aggaaagttt attcttgagc tgcaaaaagc tgctactgaa
    21601 catagtctag ttatcttaca agtaagagca aatcgtttga gtagcaagta tgaaacgatc
    21661 tcaggctggg tggcgacaaa aacggtcgaa aaagaccgag tgatgatccg cctacaaaac
    21721 gaagagcagc agatccggat ggttcctgta gaacaaattg aaaaaataac aatcctttca
    21781 ccagcagggg aacaggaacg gttatcaaaa taatttatac cagatagaaa agcacgtatg
    21841 agcttgtacc agcaatcatt actaatcaaa aataaccgaa tgctttaagc tgatatcagt
    21901 aaaacggaac gttttaggat gagtatcata gcatgacagc attcggttga ttagttgaat
    21961 cgattggatg gtacaagttt ttttgataaa aaaaggtcct gctagccggg gagctagcag
    22021 gataaggagt taaaaatgaa aaagtgttgt tagggttgtt tgttggtatg cttatataat
    22081 agtcattagt tgtgaatatt ttgtgacgaa agttttcgaa agttgttaag tt
//
LOCUS       DBBGSP010000049        20833 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000049 DBBGSP010000000
VERSION     DBBGSP010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20833
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.049"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..456)
                     /locus_tag="ACIZE9_002176"
     CDS             complement(<1..456)
                     /locus_tag="ACIZE9_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HGC6094022.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEK"
     gene            complement(561..1424)
                     /locus_tag="ACIZE9_002177"
     CDS             complement(561..1424)
                     /locus_tag="ACIZE9_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HGC6094023.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(1620..3719)
                     /locus_tag="ACIZE9_002178"
     CDS             complement(1620..3719)
                     /locus_tag="ACIZE9_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HGC6094024.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(3939..5048)
                     /gene="rpoD"
                     /locus_tag="ACIZE9_002179"
     CDS             complement(3939..5048)
                     /gene="rpoD"
                     /locus_tag="ACIZE9_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGC6094025.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(5072..6913)
                     /gene="dnaG"
                     /locus_tag="ACIZE9_002180"
     CDS             complement(5072..6913)
                     /gene="dnaG"
                     /locus_tag="ACIZE9_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGC6094026.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(7095..9410)
                     /locus_tag="ACIZE9_002181"
     CDS             complement(7095..9410)
                     /locus_tag="ACIZE9_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGC6094027.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(9595..10455)
                     /locus_tag="ACIZE9_002182"
     CDS             complement(9595..10455)
                     /locus_tag="ACIZE9_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGC6094028.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(10514..11146)
                     /locus_tag="ACIZE9_002183"
                     /pseudo
     CDS             complement(10514..11146)
                     /locus_tag="ACIZE9_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
     gene            11313..12074
                     /locus_tag="ACIZE9_002184"
     CDS             11313..12074
                     /locus_tag="ACIZE9_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6094029.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            12100..14691
                     /gene="mprF"
                     /locus_tag="ACIZE9_002185"
     CDS             12100..14691
                     /gene="mprF"
                     /locus_tag="ACIZE9_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HGC6094030.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(14879..16066)
                     /gene="tuf"
                     /locus_tag="ACIZE9_002186"
     CDS             complement(14879..16066)
                     /gene="tuf"
                     /locus_tag="ACIZE9_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGC6094031.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            16434..16790
                     /locus_tag="ACIZE9_002187"
     CDS             16434..16790
                     /locus_tag="ACIZE9_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HGC6094032.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(17031..18035)
                     /locus_tag="ACIZE9_002188"
     CDS             complement(17031..18035)
                     /locus_tag="ACIZE9_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGC6094033.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            18201..19052
                     /locus_tag="ACIZE9_002189"
     CDS             18201..19052
                     /locus_tag="ACIZE9_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGC6094034.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            19069..19314
                     /locus_tag="ACIZE9_002190"
     CDS             19069..19314
                     /locus_tag="ACIZE9_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094035.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            19501..20205
                     /locus_tag="ACIZE9_002191"
     CDS             19501..20205
                     /locus_tag="ACIZE9_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094036.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            20613..>20833
                     /locus_tag="ACIZE9_002192"
     CDS             20613..>20833
                     /locus_tag="ACIZE9_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGC6094037.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQMLKVKEK"
BASE COUNT         5919 a         4259 c         3645 g         7010 t
ORIGIN      
        1 tttttctttt tcatagcatt cctgacagat tccatggaac gttagccgat gatcttttac
       61 taaaaaatga taacgttctt ctactacttg ctccacttca agtaaaagat cctcttctac
      121 ttcctcgatc gtgccgcagt tcaagcatag taaatgatga tggaaatgtt tggcgccttc
      181 ttttctcaaa tcataacggg ctaatccatc attaaaactt actttatcga caattttcaa
      241 ttctgtcaag atttcaaggg ttcgataaac agtagcaagt ccaatttccg gactcttttt
      301 tttcactaaa aagaagattt cttctgcaga taaatgctct ttctcatttt ccaaaagcac
      361 aagcagagta gcttctcttt gcggtgtcag cttaaacccc gcttcatgta gctgctgttt
      421 tgtttttttc atcgccgaaa tagcattcat gaccatttac tcaaccccaa caatttataa
      481 taattacaaa taaaaaaaga tataacacta tgttaattaa aattattata agctagttaa
      541 gaaaaacatg caagggattc tcaattagat tttttgacta gttttgtcac accgttttct
      601 tgtgtaatca atccttgttt caaaagatta cctaatgcgc gcttaaatgc tcctttgctg
      661 ataccaaaag ctttcatgat ttcttctgga tccgatttat ctgtaaagtt gatttgctga
      721 tctgcagaac gttctaaaat ggttaaaatc atttgtgcat catctgatat agcttcatat
      781 gctcttggct tcaatgaaag attcagtaca ccgtctggtc ggacaccaat cactcgacct
      841 tttatctgct cgcctagacg aggttcatta tatcgttcag aaggatggat aaacccaaga
      901 tagaaatctt ccgttaaaac gtacgtacct gttaatttca agcggtatgc tgttcctatc
      961 acatctttgt ttttcatttc ttctgttcca tatttgctta aagatttgaa tattttttca
     1021 tctgctaaac tgccccaaat acggtctttt gcatcaactc taagggaaat catcaagcga
     1081 tccccttttt taggccatag ctctgtcatt gtcggcaatt catcaagaga tacgacaaag
     1141 tctttatctg gaagaccgat atcgacaaac gcacctaaat cttttcgtgt agcagtaacg
     1201 attccaaaag cgtaatgacc gatacggctt ttaggaattt gtgtagtgat ccgattttca
     1261 tgtttttgat tttggtaacc gaatccttca actgcttcac cgattttgtg ttcaccttct
     1321 gatttgctta agccaaaggt ttgtccgttt ttttggacaa agtagttttt ttcattttca
     1381 tcaataataa tacctgtaaa tatagttgct aataaatcgt tcattttttt ctccctctat
     1441 agtgaaaggt tttcttaata catttctttg ctatcataac ataatgttat ctacttgaat
     1501 agctgagcct tggtttggaa aggtgaaaaa aggagtatga caacagttgt gtcatactcc
     1561 cctttttcga ataaacggtg ttaaacggca ggctcacagc ctctttcatt tgcctaaaat
     1621 taattgctcc catttcctcc gaaccatcca gttttacagt tgatggttac gatgtaaaat
     1681 ggcaaagcac tttctccaat gcctttcatc aatgcagatt ttgttgaagt ggcatataga
     1741 ttataatagc cttccccatt ttcgattctg gctttttcta atctgtaacc tccttcaacg
     1801 atatatccac gttggataca tgtagcaatc actttgcttt ggacacctgg tgcccacgtc
     1861 catgctggat tagatgcatc ggcaatatca cttgctctgg cagatttgat tggctgattc
     1921 gctgagtttg aagaggaagg ggtcgaggat gccgcttctt gctgtgctgc ttgtgcgacc
     1981 gcagcttgtt gagcggcttg agctgcagct gctgcttgag cggcttgttt tgcttgttct
     2041 tcagctgctt ttttcgcttc ttctgctttt ttcttttcct cttcttcttt tttctcttta
     2101 tcagtgagca tcttatctac ttgtttcaat tgttcattca actgagcaga tagatctgta
     2161 tttttcactt tttctactgc ttcttttgcc gtcttgtatt ggtcgcgtgt tgctgaatcc
     2221 actacttttc cgtctttaaa gactatagct gttttttctt tagctgtttg caattcagca
     2281 tattgatttt tagcttctgt ttgtgcttgt tgaatcaatt ttccaaaatc tgtgttatcc
     2341 gtttcgattg cttggatctc tttatctgct ttcaacttga tgtcatctgc tagatgatca
     2401 tcgacgatgg caggtgctat gaaccactca ttcacttttt ggatatctcg gatcttagat
     2461 tggatatctt ggtaagttgt ttctaactct gaatatcctt tttcattctt aagactggat
     2521 aaatcatttt ttagttttga taaatcttga tgaatcatat ctgcacgaat aaattgatgg
     2581 tgatcatctg tataaaaggc agcaagtttc tcatgaagtt cttccatttg ttgctgtctt
     2641 tttgcttctg ctgctacttc ggcttctact ttttgatgat ggtcataata agcccagctt
     2701 cctccaccga gtagaagtac tgctgctaaa acgagataag gtactttttt tgattttttc
     2761 ttttgcgctt tatctggatc tgttttttct aagtttgatt cttgatgtgt tttttcagta
     2821 tctggcacga ttgttattga tttcgcttct gcttcaaaca gcttaggctg gttctcttct
     2881 ttttctattt ttgcttcaag atcagtaccc tctttgctta cagattgatt ttcagcatcg
     2941 gattcactat ttatttcatc gggctctgtt gactttttgt ctgtgttttc gagtatttct
     3001 tttttctctg cttccggcag tttattcgtt ttttcctttt ctaattgttt ttcagtaaat
     3061 acttcagttt tttctgtgat atccgttttt acgtctttta tttttactgt ttctttacct
     3121 gtggcgtttt ctctatcaga gtctttttca gtttcttgtt ccttttctgg ctctactttg
     3181 ttttcctgtg caattttttc actgatcatt ttgagcagct ctttcgcgtg ctcttctttt
     3241 gtatcttcac gatgtgcttt gatataagcg gatagtatcg aattttcttc ctcattatcg
     3301 acgatttctt tcagttcagc tactcttctt ttttgttttg attcaagcgt ttcttcttga
     3361 ttctttcctg attcttccga agtctcatga acagttgctt tcttctgttc atttttctct
     3421 atattagtta cttgatcgtg agcaggtggt tcttcgtctt ctggttctgc tttttcgaat
     3481 aattccatta cagattctag aggtaaatct ttcaattccg accattcgat tggatcgttt
     3541 aattctgtat caggaaagac tgcatcttca gttgatttat cctgcatagc tgcatctgta
     3601 tttgtttctt caattgattc ttttatttgc tgatcttctg cagttatttg atgaccgcag
     3661 tctggacaga tagtattctg ctccattttt ttcgatccgc aatttggaca ttttttcatc
     3721 acttagcgat cggctccttt actaggttta cgctaccatt taatctatca tattctatac
     3781 gtcacgccaa tagcttattt ttaggattta cttaaaaata atgaatgaat ttccttccta
     3841 tagaaaaaaa agcttgagac tgcgtagtct caagcttttt ttcttttaaa ataaaccaaa
     3901 cagttttact gatttctctt ctggtcaata gtccacgctt attctaagaa atcttttaat
     3961 tgttttgaac gagaaggatg gcgcaatttt cttaatgctt tagcctcgat ctgacgaata
     4021 cgttcccgag taacaccaaa tactttccct acttcttcca atgttctcgt ccggccatca
     4081 tctaaaccaa aacgtaagcg aaggacattc tcttcccgat cagtcaatgt atctagtaca
     4141 tcttccaatt gttcttttag taactcataa gctgcgtgtt ctgctggact tgttgcttcc
     4201 tggtcttcta tgaaatcacc taagtgagag tcatcttctt caccgattgg cgtttcaagg
     4261 gaaacaggtt cttgcgcgat tttcaagatt tctcggactt tttctgttgg aagatccatt
     4321 tccgcaccga tttcttctgg cgtaggttct cttccaaggt cttgcagcaa ttgacgttgg
     4381 atacgtatca atttattaat tgtttcaacc atatgaactg gaatacggat cgtacgtgct
     4441 tggtcagcga ttgctcgagt gatggcttga cgaatccacc atgtagcata ggttgaaaac
     4501 ttaaatcctt tgcggtagtc aaatttttca actgccttca tcagtcccat gtttccttct
     4561 tggatcaagt caaggaactg catgcctcgt cctacataac gtttagcgat acttactact
     4621 aaacgaaggt ttgcttctgc cagacgctgt ttcgcttctt ggtcgccttc ttcgattttc
     4681 aatgctaacg ctacttcttc ttccgcagtt aaaagggaga cacggccaat ttctttcaga
     4741 tacatacgaa ccgggtcatt gatttttaca ccggttggcg cagaaagatc ttctgttttt
     4801 gcttgttcag cttttttctc agcactcttc aagctgtgaa ttgatggatc accattttca
     4861 tccaccacac tgatacctgc gtcttcaatc ttttggatca atttgtccat ttcatctgca
     4921 ttcaaagtga atggtgtagc aagctgattg gataaatcat catatacaac ttgtcgtttg
     4981 ggtttgtttt ctttgatgaa agctgctact gctgcttcat acgttttttt atctgttcca
     5041 tttgccataa aagaaggccc cccttgagta gctatttggc ttgttttaac tgtttcgtta
     5101 aattgatgat ttcaatcgtc aattcaagct caagctgttt gtttccagtt cgtctggctt
     5161 cttgctgcat ttgttttttt aatgttattt catcagctaa gccagatttg ctgatcacat
     5221 ctagcaagtc ttggatttct cgtggcgaac tttcttctgc caccggtaaa tattcgattt
     5281 ccaccaccaa ccgccttaaa ttttcatctt gcaaaaagtc taaaaactct gcaaggttga
     5341 attcataatg ttgtgagaca tatgcatcga ataaaaaata aacttctgca tatgcatcat
     5401 gaataaactg aaattctcgt tcttttaaaa tattacggac agaaacttct ttaaatgcac
     5461 gatataatag aatctgctct gccttttcta cttgcgtcaa aggtctcttt ttccgtgcag
     5521 tttcttgtct cgtaacctga gtgtgttgac tttcctgagg ttcttgacga ttttgctgat
     5581 ttgtccttcg aagatcgcgc agttgttttt gtatcgtctc tctgccgatc tgaaactctg
     5641 ttgacagttg agatagatac atatcttgtt cgattggtga aacaactcgg ctaagttcaa
     5701 ctagtaattc ttcgaggtat tcgatcttgt ctttttcatt atctaaattt ttcccttgtt
     5761 ttaaataacg tgatttaaaa gtaaagactg tttcgcgccc atgagccact aattcttgga
     5821 aagatgcttc tccatactta cggagatatt catcaggatc aagcttttct ggaacgacta
     5881 cgacagaaag tgctaatcga ctgttttgcc gaagcaattc aatccctcga ttggttgctt
     5941 caaaacctgc gttgtctccg tcatagcaaa agaccaattc tttcgtcagc ttttccattt
     6001 gttggatctg ttgagctgtt agacttgtcc ccatagaagc taatccagtt ttgataccag
     6061 cctgccatgc agcaatcaca tccataaacc cttcgaacaa caaaatttct ccgtttttcc
     6121 ggatatcgct tcttgcttta tcaagattaa ataaaacttg tcttttattg aacagttctg
     6181 tttctggact attcaagtat ttgggctgat ctttttcctg ccctttttca ggtgcaagcc
     6241 agcgtcctga aaaaccgatc gtctggcctt gagaattacg aagtggaaac atcactcttt
     6301 gataaaaacg atcagacata cggccatcat catgcgtgac aaacaatcca gagcgttcta
     6361 acaattcatt tgaaattgat tcattcttga atacttgctg aagaaaagaa cgctcattag
     6421 gtgcaaaacc tatgttgaat tcttcaatta attctaaaga caacccacga ctttgcaaat
     6481 attctaaagc tggctgtcca gcttttgtat gcaatagcat gtgatgatag atttccgctg
     6541 ctttttcatg agcagcaatc agtttccccg tagcagattc aggattttgg acagctatag
     6601 tacgctgacg ccattgatct tctaacggta tctgttcgaa gtctgccact tttaccactg
     6661 cttctggaaa acttagacct tctagttctt gaagaaaagt aaacacgttt ccgcctttac
     6721 cacaaccaaa gcaatgaaaa atctgcttgt cttctgcaac agaaaaagac ggtgtacgtt
     6781 cttcatgaaa aggacacagc cccaagtaat ttttaccaga ctttttcaac tggacatatt
     6841 gtccaatcac ctcaacgata ttcgtttgac tgcgtactgt ttcgataacc tcttgaggaa
     6901 tccgttgagc cattttttca ccccctgctc tattgatatc ttttgggttt aacagaagat
     6961 atttcaggag aataaccggt aaaaaatcgc actaactgaa atcagtgcga ttttaaagga
     7021 cacaattata catgtttgat tgtatcatat ttcattgctt tttcaagtat aacacatttc
     7081 tatctcatta agcatcaatt tgctactctt ttcagtaact gattttgaat atcagccttc
     7141 cagtacaata ctcgaagaac aatatttacg agcatgaata caaagaagta tcctacgctc
     7201 tctcccaacc ctaagtttac ttccaaaatt ccatggaaca gcattgcagc tacatatatc
     7261 cctacgatcg tcgttactgc taggaagatg cgcaatgggt tgaagggata acaagctttt
     7321 acaactgcca tgcaactgat cccaatcagc aagtaataca tcaaagtagt agtttcagca
     7381 tttccccatg cgaatgtttt tccaagtaga tacaccgcaa tgatattcac tactacaagc
     7441 aaggcatttg gtaaagcatt aataagtgct gtaggcaaat aacggtaagt gatttttctt
     7501 ttatcttgtt caaaagataa aaagaaggaa ggataccctt caatcgctaa atcaatcagc
     7561 gtgatttgga tagggataaa cggaaatcca attgctgtaa cggcacatat aatcgataaa
     7621 ataaatgaat aaatcgtttt gataaaaaag atgcctgaga ctttcgtcac attgttgacc
     7681 actcggcgtc cttcaaacag gacttctggc aatgtagtaa aatcagagtc caacaatacc
     7741 agattcgcaa tctgacgtgt tgctccatca ccttctgcca tagcaatgct gcaatctgct
     7801 tctcttaacg ccaaaacatc attcacaccg tcgcctgtca ttgcaaccgt tctgccgctt
     7861 tctttcaatt catttaccag caatttcttt tgctgcggac tcactcgtcc aaaaaccgta
     7921 tagcgatgag cagcttctcg cacttccatt tcttcagtaa tttgagaaag atcgacatac
     7981 gcatcataat tcggtaatcc tgcacgtcta gcgatattgg agacagtaaa aggattgtct
     8041 ccagaaatca ctttcagatc cacaccttcc tcatgaagat aagctagtgt ttcttgagcg
     8101 ttttttcgga ttggatcatc gatttcaaac agagcaaccg gctcaacaaa tgctggtttt
     8161 tcttcgttca attgctgatt tggagcgatc cccaacataa gtacgcgata gccattcgct
     8221 tgggctgttt ttagactgtc cggaagccga tcttcttcca ccaaacgttc aggcgctcct
     8281 acgtacacga ctcccagttc tggaaattcc atcgcgcccc atttgcgatc agaagaaaat
     8341 gcgactttgt ttgtcacatc ataccgatta gaaagctcaa aataatctct catagcccgc
     8401 atagtgatgt tgttatcact gctttctgcc agatacgtcc ccataatttc tgggatggct
     8461 ttctcgtaca gcggatgtag tgcttctacc cgctggatac tcattttccc ttcagtaatg
     8521 gtccctgttt tatccaagca taatgtatcg acatgggcca gcgtttcaat tgaatacatg
     8581 tcttgaacaa ggattcgttt ttttgccagt ttggttaccc ctgtcgttaa tgcaatactt
     8641 attagcaata ccaaaccctt tggaagcatg cctaacaaag ctgctgcaga tgcaataaca
     8701 gaaattttga tagaagcatc gcggatgaac agtgcttcca aaaatagtat gatccccaaa
     8761 ggaataatca cgaaactagt gaatttggat actttgcgaa tcgaatctac aagttcagaa
     8821 cgaatagctt tgtgagtctt tgcctcgcta gtcaagcgga cagcataatt atctgcacct
     8881 actcggataa cttcagccat gacagaaccg cttgtcaaaa agcttccaga aagcaattca
     8941 gctccagttt ctttgacaat caaatcagat tcgcctgtca aaagagcttc atttgcttct
     9001 gcccgtccag atataacctg taaatcggct ggtatctgtt ctcctgctcc gatttttacc
     9061 aaatctccta ataccagctc tttagtagaa atcgattgtt ctttaccgtc ccggatcact
     9121 agtacttctg attgggaaac aatcgataat ttccgtacaa gatttcttgc atgtatttct
     9181 tgataaattc caataacgat attgacgaca ataattgcta aatacgccat gttggaatac
     9241 gcacctacaa ataacagaca aatcccaata ccaaagttca gaaaattgaa taacgtcaat
     9301 atattatcgc tgaatatttg ttttgtactt tttgatgcat cttcctggta gtcattttgc
     9361 tggccagaag ccattttctg aactacctct tgctgtgtaa gtccattcat tttctttttc
     9421 tccattttcc gccaactttc aaaaataatc acgtgtttaa gtctagcgtg ttccaagatt
     9481 aaaaacaact tgtttttata aaatttatag aaaaacacac gaatgatttt acaaaaaaga
     9541 tgccaacctt tttgtttgaa tcacccgtgt gctgttttta ttatcaatct atctttactt
     9601 atattgttcc tccaaacggc tcatccacca acctagtgct gtaccggcta taaaaagaac
     9661 aggacaagct agtaccccag caactcccaa tcccgcgtaa tcggtaggaa tgatcataat
     9721 cgttgaagca aaaactacac ctaaaatgaa atggaatagc ttgctatatg cctttgagaa
     9781 aatgtaatcc atgatttttg acaatccaag aacacaaaga atcccaccaa ttccgatcgg
     9841 cacaatcact tcaagtcgta cttctttaaa tccgtcagcc atcgctttat acaatcccat
     9901 atacaccaaa aaattagaag ggctcaatcc tgggacgatc atacccaaac caatcaatcc
     9961 gccggcaatc agccatgttc caaaattctg atcgacttgc ccgtcaaata attgagcgcc
    10021 gtataataaa aacaaataag ccagaacaaa agtaacaacc atgatgatca catcagaagt
    10081 atctcttcct tttttccctg cttctttcca taacgcagga acagttccag cgatacatcc
    10141 gacaaaaaac cataatatcg ttgtttcata cgcacctaat aaaaaactga ctaaaaaaga
    10201 aagtagaaag atgcctgtca ctccgcctag accaacaggc agaaaaaaca aaacattttc
    10261 tttgaaattt tttgtaaggt gggctaaaaa agaaatcagc cgctcataca tgccaaagac
    10321 agctgctaat gcaccaccgc tgactcctgg caagataaat cctgaaccga taaacattcc
    10381 cttcacaaac cgtaacatcc agtctttggt tgtgtacccc acttcttgat tttccatttt
    10441 ttgccttttt tccactattt gcgtactcct tctttcattt aattttattc atgattgaac
    10501 atttcctgct attttactta aagacttttt cataggtctc tattattttt tcattcattt
    10561 tgacaatatc aggataaaac atgttacctc cattatgata gagatagccg ccattgtaaa
    10621 gcaaggactg gatccgccaa tatcggtatt gtttcccttc ctcatttcct aaaagtgggc
    10681 tcagcacatc tttagaatac gcttctgcta attctactgt gttttctccg ccatgatttt
    10741 ttacataggc aatataatct ttcccaaaat tatatgcttg gacagctgtc cataaatcgc
    10801 atccttgttt ctttgcttct actatcattt ccgccaaata tttgacacct tgatcaatac
    10861 tgtcagctgg attatcaatg atctcagctt ctccatgcag actttccgag ctctgcatga
    10921 gatctgtccc ttttcctttt gattcggtca atattatcgc cttgatcaaa ttctcgtagt
    10981 tttccatatg ataatttttt gcagctgttg ttatttctat ttgatagctt tccactcgtt
    11041 ttaccgaacg ataagttctt cctcataaaa acaacaccgc accaataacc gtcagaatga
    11101 tcatgtaaaa aagaatacgg ataatagata atcgttttcg cttcatttca tcacctagtt
    11161 attttgacat ctttttttat cttactattt ctttatcttc ttggctattt cttccttgat
    11221 ttctgtgtac gccttaagaa aaaatgaatt ttcctgtatt ttttgacatc ttacgaaaat
    11281 gatcgttgtt tttcagtaaa aacaattgcc caatgactga tataatcgtt atactttaca
    11341 cagtaggtga ttatgtgaaa aaagaaaaga aatatgcaaa aatgccagat gggagcgaaa
    11401 tttactatga aaagagcggt caaggcttcc ctctcttttt actgcatggc aatgacggca
    11461 gcggccgctt tttttcagaa caggtccctg tactcgaacg ctactatacc gtgtatctag
    11521 tagatagccg aggacatggt cgttcgacaa acgaagcatc tatgttgaat tttcagttaa
    11581 tggccgagga tctgaatacg atcatgttgc tggaaaaaat cgatcaggca gattttcttg
    11641 gatttagtga tggagcaaat ctagcactgg tatttgccag cagcttccct aaaaaagttc
    11701 atcgattgat tttaaattct ggaaacacgc ttgttaaagg cgttcgtttt tctgccagag
    11761 tcatcagtaa tattcattat gcatgggtat ggttactctc tttatttcgc ccaagtcttc
    11821 gcaaaaatct tttagttatc aaacttttgc tgcatgacat cgggcttaca gaaaatgatt
    11881 taaaaaaaat caactccccc actttgatca tcgtgggaaa aaaagatgta atcaagctaa
    11941 aacattcttt gtatatagct aaaactatac caaaagcttc ctttgtgctt gtgaaagaac
    12001 aaggacatga attagctaga aaagatcctg aacgcttcaa tcgagaagtt cttcaatttc
    12061 tttctgaaac ataactatta ggaatagaag gtgatttatt tgttaaaaaa taccatacaa
    12121 tggctgaaaa accacctagg actgttcaaa acaatctttt tgatttctgt cattgtcatt
    12181 attgtcggtg aattgatgtc catcggtaaa actctatcta tccagcaatt aggagaaacg
    12241 tttgccacta tacctgtatg gaaaagcgga ctaatgctat tgattggtct tatctctgtg
    12301 ttacctatgg ttggttatga tattattttg aatcggatgc ttgaacaaaa gcagaatcct
    12361 cgttacctgt ttgagacaag ctggctgatc aatacgatca acaatattgc cggtttcggc
    12421 gggtttgtta gtgtggggct tcgctctgaa ctatatggac aaaagaaaga gagcagaaac
    12481 gtgatccaag cattatcgaa agttttcttg tttttgatgg ctggactttc tatttacagt
    12541 ctgctttctt ttttacttgt agtcttcacg ccagttgctc cttttttgaa gcaatattgg
    12601 atatggttga tcggcggcgg tctatatttt cctgtcgtct ttttatttac tactttcaaa
    12661 aagaaaggat tccttggtgg tacctcactt aaaactcaag gacagctatt gctagtttca
    12721 ttgttggaat ggaccggtgt cctgtttagt ttcctttctg ttggttattt aatggaaatc
    12781 cggattgatc tgtggcaaac aattccatta ttcattgctg cttcagtgat aggaatcgtg
    12841 tctatgattc caggagaaat tgggagtttc gatgtaatga tgattatcgg gttgtccgct
    12901 attggtgtgc caagagaaat agtcgttgtg tggatcttgc tctatcgcct gttctactac
    12961 atcattccgt ttttgattgg aatcgtcttt ttcttcaaaa atatcggttc cacttttgat
    13021 cagcgttatt ctggtatccc taaacaatta gcaacagaaa ttgcgcataa aatcgtggtt
    13081 gtcttattat acttttctgg aatcatgcta gtactttctg ccactatccc gcaagctttt
    13141 acagagtttc gctggcttca tagtttgaac ccattgaaat ttcattttat tatccaattt
    13201 cctagtatac tattgggatt tcttttaatc attatgggca gagggatcgc agcacgtgtg
    13261 aaacgagcat atttgcctac aatcttcttg attgttctag ctttacttta tgttttatta
    13321 agtgatttta gtttcacacc ggtggttttc ttgtctattc tgcttctgat cattcttgct
    13381 tctaaaaacg aattatttcg ggaacaattg atctattcat gggagtggcg tacgatcgat
    13441 ggaatcatta ttggtgcact gtccttgctt tacatcgtta ttggggtata caatctgccg
    13501 gatttccctc atcggcgtca ccattttatt tcctttttct tatttccttc tgaaaagatt
    13561 tggttttcgg gattgttggc catcatcgct gttagtttca tgatcgttct atttgttcat
    13621 ttccttcaag gagaaaagaa acagattggc gaagccttta atgaagaaaa ggccctgaag
    13681 atccttacaa cttatggagg aaactccgat agtcaattga tcttcttaaa agataagcgg
    13741 atgtttgcct atgaaaaaga cggtgaacca actgttcttc tccaattcgc ttgcttcaat
    13801 aataaatgta ttgtaatggg tgatccttct ggtaagaaag aagattttcc agaagcaatc
    13861 gaagctttta tcgaagaaac agatcgacta tgctatttac cagttttcta cgaaacaagc
    13921 gaagagattg ttatgatttt gcatgaattc ggctacgatt tcattaagat gggggaagaa
    13981 gcttatgtag acctgaatag ttttacaact tcagggaaaa aaatgaaggg cactcgtgct
    14041 gtcttgaatc ggatcgaacg agaaggattt acatttgatg tcttacaacc accattttct
    14101 actgagcaaa tgagtacttt caaaaatatc tctgataatt ggttgggttc acgaaaggaa
    14161 aaagggtttt ctttaggctt tttctctgaa gattatctac aaagagcgcc tattgcagtt
    14221 gtcaaaaata cccaagaaga aattgtcgct tttgcaacga tcatgcctac ttacacgaac
    14281 aataaagtag gaacgattga tctgatgcga tatgattcta aaaaagcacc ttctggcagt
    14341 atggatttct tgttcttgca tttgtttgcc tatatgaaag aagaacatat ccaatggttc
    14401 aatttaggga tggcccctct ttcaaatgtc ggaacttcca gaaagagttt tttacaggaa
    14461 aggattgcat acttggttta cgagtttggt tctcattttt attctttcca tggattaaga
    14521 gaatataaaa gcaagtacgc tacaaactgg gtctcacgtt atactctata ttctagagat
    14581 agttggattg catatgttat gattgctttg ctgattattg ataatgcgcc agttgagcag
    14641 acacaaggta gaataagtgg tttgaaaaaa tggatacgaa gaaagtatta aaaactgcat
    14701 accgatagat gaacactctc atgatgaata aaagagactg aagtaaaacg aaagttcatg
    14761 cttctacaat ctcttcttat acaattgaag aacaaagagc ggtccaaaca gaaatcctgt
    14821 ttggaccgct cttttatttt aaacattttt cattaccaaa atattcgagt cgcgtttctt
    14881 atgcttcgat ctctgtaacg atacctgaac ctactgtccg tccgccttca cgaattgaga
    14941 atgtcgttcc gttttcaaca gcgattggat ggatcaagtc aacatcaatc gtcacgttgt
    15001 caccaggcat gaccatttct gtatcttctg gcaatgtgat tgttcctgta acatcagttg
    15061 tgcggaagta gaactgtgga cgatagttgt tgaagaatgg agtatgacgt ccaccttctt
    15121 cttttgtcaa cacgtacact tctgctttga attttgtatg tggagtaatg gaacctggtt
    15181 tagcaagtac ttgtccacgt tcgatatcgt cacgttggat cccccgtaac aacacgccta
    15241 cgttatcccc agcttccccg taatctaacg ttttacggaa catttctaca cctgttacaa
    15301 ctgctttttg tgtttcaggt ttgatcccta cgatctctac ctcatcaccg acacgaacag
    15361 caccacgatc aatacgacct gaggcaacag ttcctcgacc tgtaattgag aagacgtctt
    15421 ccactggcaa tagtaatggt ttatctgtat cacgttctgg tgttgggata tattcatcta
    15481 ctgtatccat caattccata atagcagctt cagcatctgg atcgccttgc aatgctttta
    15541 atgcggaacc tttgatcaca ggagtgtcat cgcctgggaa accatattcg ctcaataact
    15601 cgcgaacttc catttctacc aaatcgatca attcttcatc atcgactaaa tcaactttgt
    15661 tcaagaaaac aatcaggtat tttacaccaa cttggcgtga caataaaatg tgttcacgtg
    15721 tttgaggcat cggaccgtca gttgcagaaa caactaagat tgcaccatcc atttgtgctg
    15781 cccctgtaat catgtttttc acatagtccg cgtgtcctgg tgcatcaata tgcgcgtagt
    15841 ggcgtttttc tgtttcatat tctacgtgtg cggtattgat cgtaatccca cgttcacgtt
    15901 cttctggagc tgcatcaata ctagcatagt cttgaggatt tgctaggcct tttttgccta
    15961 atactgtagt gatcgcagca gttaaagtag ttttcccatg gtcaacgtgt ccaatcgtac
    16021 caatgttaac gtgtggttta cttctgtcat aatgttcttt tgccataatt tacaaacctc
    16081 ctaaataata tagatcactg aaaaatttca gctctcacct ttttattata gtcttttttt
    16141 gactaaatca aaaagaatac gtccgactta ctttttgtaa gattcgaact aagcttatta
    16201 tacgtcaata ttggtcaaag tcaactaaga gcactcgtct gtcttatacg cgaaaaaagt
    16261 accttttata aataaaaaaa tgtgtttttt gagaaaaact tcaagatagt ccttaacttt
    16321 cttttgaagc aataagaaca aaatgaggaa aagtttaaaa ttcagctgtt gccaacaact
    16381 ttcaatagac gaaatcttct atttcgttaa taataaggaa agaggtgaag tacatgaaaa
    16441 aattaattgg cgtacttgtc gttttaggca tatttctcgg cggaagtttt gcagcttatc
    16501 attattttta cggcggcgaa gcttattata caaaaatcac gacgaatggc gaaatgtcag
    16561 ctacccaagc agataacgga gagaaattca cgacttatac ctacaagcaa gcggcttata
    16621 ataaagatgg tgaaaaaaaa caggtgacgc ttcgcgaaga aagagaacat ccattaaaga
    16681 tgaatgcgta tcttaaactc aaagtcaatc ctcgtaaagg tgtattaagc tgggaagaaa
    16741 taaaggcttc tgaagtgcct aaaaatgcgg cagaaaaaat cgataattag taaatggtct
    16801 taaaatttta ttagataaaa agaggctggg acagaagcgt ttaactccaa gaaataagaa
    16861 ggagttgctt ctgcttccgc cgtttatacg tgtttagagc gtgagacaaa agtgttcttt
    16921 acttttgtct cacgctcttt ttttgttata ttcgtctttt ccgatccttc tcttgacaca
    16981 attcatttaa ctgatcactg gtacttgaac acctaatatt ctagtcattt ttataaacga
    17041 ttcaatactt catccacatt tttgatcatc acggatatcg taccatccgg attattcaca
    17101 aattcaatca aatctgggtt gcgatataca tctactggta cgatcagttc gatcccgttt
    17161 gatagcttga atttttgttt tccaaatttt ttctcagaaa tttcttgtac ttcttttaca
    17221 ggaggtgctt ctgggacaaa tccttgctct tgtacttctt ctttaaaagc catttttgcc
    17281 gtgatgtttt ccttgaagac tttttccgca atcatctcat gatccaaccg acctttttct
    17341 tctatcgtat catagacagc ttctttcaaa tcagccatga tatcaaattc ttctgtctca
    17401 aatttttttc caagatgctt ggctactttt tggatcactt ttacattttc ttctaaagaa
    17461 ggtgcaggaa cactttcgat cactcttcca gaaaaataaa gctctttttt gccagaaaac
    17521 tcatattttt tttcaattaa ttcgtaggtc caatcagtca aattcacagc gaatgcttca
    17581 tctgcttttt gtgttttcgc ccctagaatt gctcgattca aaatcaagcg gttgtcgatc
    17641 cctgcttcgt ctgcttcaac aaagtgagtg taagcctcac gataattgac tttcaataaa
    17701 gataagtaca tcactgtatc taattcatac aagacaacaa atacatctgc actaggtgct
    17761 tcttcacttt cttggtagat atcgaaccac cgctgaacga ttgcttcact tgcttccaca
    17821 aaattttctt gagcgatttt aagtgattca acgatcatgc tttcttctgc tagttgtcca
    17881 gtttttgttt gagcagaaga gattttttgg atcttctttt gaagaaaatc acgaatatat
    17941 tcttttgtca gatccagctc tttttgtgaa aagactggag aaccagtttc tctgtcaata
    18001 atatgcagaa ttgctttttt taaatagata tccattttct cattcccttc tgtcttagtt
    18061 tacggaaaaa aaatcaaaaa taccagaatc aaaatcattt tcttttaaac aaaaatttca
    18121 agagtagaaa caaaatggat tctttttttc gaaaaatgcg ctacacttat agttgaacga
    18181 ataaaaaagg agctgaaagt atgaattcat taacaagcac ttatcgtcta tcaaatggtt
    18241 acgaaatccc ggtagtagga ttcggcacat ggcaaacacc tgatggggat gtcgctgttt
    18301 cctctgttaa agaagcgctg gctgcaggtt atcgccatat cgatactgcc caaggataca
    18361 agaatgaaga aagcgtcggc caagcgatta aggaaagtgg aattcctaga gaagagatat
    18421 tcttgacaac aaaattatgg aatgcaaacc acagctatga acttgtgatg tcttcttttg
    18481 aagaatcatt gaagaagctc caaacagatt atttagatct gtttttgatc cactggccaa
    18541 accctgttgc ttttcgtgat aattgggaac aagcaaatgc agatacatgg cgagcatttg
    18601 aagaactgta tgaagcaggt aaaatcaaag caatcggtgt gagcaatttc ttaccccacc
    18661 atctagatac actagcaaaa acagcaaaaa ttatgccgat ggtcaatcaa gttttccttg
    18721 caccaggcga attacagaca actgtagttg agtatgcaaa aaaacatgat atgatcctcg
    18781 aagcatatag tccattaggc actggtaaaa tcttcgatgt gcctgaaatg aaacaaatcg
    18841 ctgaagcaca tgacaagacg attgcacaag ttgctttgcg ttggtcgctg caacacgaat
    18901 tccttcctct tcctaagtca gtgacaccaa gcagaatcaa agaaaatact gaattatttg
    18961 attttgaatt aacagaagaa gaaatgaaac aaatcgatca gttagatggt gtagtcggca
    19021 aagcaaaaga cccagatact acccaatttt aagtcgaaag gtgattttat ggatccaatc
    19081 gaacgcttga attctctctc ggaagaagtt acccagactt ttcattccga ttttgtcttt
    19141 ttgatcgatg cagagaaaat ccaacatttt cctgcaagaa actggacaca tgatcaaatc
    19201 atcgaagaac tgaaaaaacg gttcgatcat tcgctaatgg tcaaaccctg gcacgaacat
    19261 gaagtcattt attcacctga actacctgtt tttgccttga taccgaaaaa atagaaagaa
    19321 tggaacggat tatgtatata tacataatcc gttccatttt ttatttttct ttcaaaaaac
    19381 gggaaaatac gcaaattttt ctgttgtaat ttgcgtatac gcaagttttt ttgcattact
    19441 ccttttcatt tggctgtttt tttcttataa tcgaaagggt atgagcgaag gagagaacat
    19501 atgaagaaaa aacagaaaca aaaattatta aatcaattcc gtccttcatt ggatggtgta
    19561 agaggacaat tattccgttc tctagaagaa gagagcttgc gacgttatgg tttgccgtta
    19621 caagtcatgc ttgatcccaa aaaccgtcaa atcttaacga tcggattagc tgggaaaaca
    19681 aatgaagata cacggatcaa cgtgccaatc gatgacaact tcaatactgt attaaagaga
    19741 attcgttcag gagaaaacgg gattttcgaa cgattccgtg acaatcttct tattgaaatc
    19801 gtgtcttact ggaatgatca acgattgaaa aacgatgaac caactgcgca agctgttgcg
    19861 acaccagtta cagaagaaac agtcagtgtg ccagaagaaa aaacggaaaa accaaaagcg
    19921 gacacaactg aaaatacacg ctcaactgat acgaatgccg ctttaagttt tgctgatttt
    19981 tcaaaagccg ttgctgagta tcctaaattt tacacagaac aaaatgaaca tgaagtagtt
    20041 attaatgaaa aaaatgctga tgaacctcgt aaattagcaa ctatttctat gactactgaa
    20101 aatgagttcg ttatcgaaaa agcactcgaa cggaaataca aagtcaaatt gactttgatt
    20161 cctttgatcg aacaatttgc agcgacagcg attactgatc gataaaaatt ctatttgtca
    20221 taaaaggctg ggatttaaaa tcccagcctt tttagtcata taataatttc tacagcaagt
    20281 aaaaagaaat tccttctaac atcaggctca aatatcagct tgacctgtcc aacaaatcac
    20341 ctatgatcct acaatgttag gcgacttctc ttctacctga agatatcttg gagttgcctg
    20401 atttcttaag atgcctaacc ttaactataa aaaattctaa taataaacat attttctgat
    20461 agagaaaaaa gcggttctat aatattttgt gttggtggaa aatcgaaagc gattttctac
    20521 taacactttt ttcttcgttt caactcaaaa agagactcac ttttggtaaa atttagtcga
    20581 ccaaaacgtc accctaccaa aggagtctct caatggataa tcatactaga aaattactcg
    20641 gattaacaga taaacattta ttttttgatg aagaatggct gattgaaaaa gaatataaag
    20701 gcgttcaagc gcagtttatt aaagggagat tggatgactc accttcccat tgtgaacact
    20761 gtggatcgat tcgtattatc cgcaacggtt cctatacgac acgcactcag atgttgaaag
    20821 tcaaagaaaa gtt
//
LOCUS       DBBGSP010000050        20680 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000050 DBBGSP010000000
VERSION     DBBGSP010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.050"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            270..677
                     /locus_tag="ACIZE9_002193"
     CDS             270..677
                     /locus_tag="ACIZE9_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094038.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            691..1092
                     /locus_tag="ACIZE9_002194"
     CDS             691..1092
                     /locus_tag="ACIZE9_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094039.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1094..1465
                     /locus_tag="ACIZE9_002195"
     CDS             1094..1465
                     /locus_tag="ACIZE9_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094040.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1501..1800)
                     /locus_tag="ACIZE9_002196"
     CDS             complement(1501..1800)
                     /locus_tag="ACIZE9_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HGC6094041.1"
                     /translation="MLFNETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(1806..2036)
                     /locus_tag="ACIZE9_002197"
     CDS             complement(1806..2036)
                     /locus_tag="ACIZE9_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094042.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(2472..3038)
                     /locus_tag="ACIZE9_002198"
     CDS             complement(2472..3038)
                     /locus_tag="ACIZE9_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6094043.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(3038..3994)
                     /locus_tag="ACIZE9_002199"
     CDS             complement(3038..3994)
                     /locus_tag="ACIZE9_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HGC6094044.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(3994..4650)
                     /locus_tag="ACIZE9_002200"
     CDS             complement(3994..4650)
                     /locus_tag="ACIZE9_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGC6094045.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            5020..7038
                     /locus_tag="ACIZE9_002201"
     CDS             5020..7038
                     /locus_tag="ACIZE9_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGC6094046.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    7108..7314
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7465..9879
                     /gene="leuS"
                     /locus_tag="ACIZE9_002202"
     CDS             7465..9879
                     /gene="leuS"
                     /locus_tag="ACIZE9_002202"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGC6094047.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            10227..11780
                     /locus_tag="ACIZE9_002203"
     CDS             10227..11780
                     /locus_tag="ACIZE9_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HGC6094048.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(12161..13945)
                     /locus_tag="ACIZE9_002204"
     CDS             complement(12161..13945)
                     /locus_tag="ACIZE9_002204"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6094049.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(13960..15681)
                     /locus_tag="ACIZE9_002205"
     CDS             complement(13960..15681)
                     /locus_tag="ACIZE9_002205"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6094050.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            15781..16542
                     /locus_tag="ACIZE9_002206"
     CDS             15781..16542
                     /locus_tag="ACIZE9_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC6094051.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            17509..17777
                     /locus_tag="ACIZE9_002207"
                     /pseudo
     CDS             17509..17777
                     /locus_tag="ACIZE9_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            18449..>20680
                     /locus_tag="ACIZE9_002208"
     CDS             18449..>20680
                     /locus_tag="ACIZE9_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC6094052.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6872 a         3585 c         4086 g         6137 t
ORIGIN      
        1 agttgttgat atagttgcta atattgttag ctaatttgtt agtaaaactg tatacgaatt
       61 tagatagtaa aaaaacagtt tgttccttat atagaggcac ttttactact gattaaatgt
      121 cagatatgct tacaaatata cttataaata tgcttacaaa attagctaat atttccgttg
      181 acaaagcttt gttactattg ttaaactaaa ttgactagca aaagtgaaac ataaatttat
      241 taaataaatg taaaaattag gagaaatcaa tgtcttatag agtacaatta ataatttcag
      301 aagatgtaga aagtcagcaa tttggcacta atgttattaa taaagtaatt aatccagctc
      361 tttctattaa tgcgccttta attcctactg ctttatcatt ttctgtaaca gctgtggtgt
      421 ctgagataga ggatacagaa aagataaaaa tagtagaaat tgaagtttta aacaagaatg
      481 aaaaacaaat tttttctacg ggtgaagtat cggtaagctt gcctcctcaa gttaacgata
      541 taaactttaa tataaacgcc agaaatgtct tggttgaaga agcaggagag cattatgctg
      601 ttgttaaatt taatggaact gagattggaa ggcaaatctt tgatatcaag gtcaacaaac
      661 cagtggaaaa aaattaagga gacgatacgg atgcttgata tagtaccatc aaatacacat
      721 cggagtggta gcttaataaa ttttgctgcg atttttgctt gcgcatcggt aattctagca
      781 tctccagttg ttgtggatgc aagttctact ccgaaaacta aaaatgataa tcaacttgta
      841 attactacaa aaaatgagat taacacaatt tcaagtaatg atggcaaaat ttttgatgtg
      901 ataaatacgg ttttaaaaag aaaagctgaa atcaatataa aatatgatga agatttaaac
      961 ttgtatttct ttgttatcaa aacaacatct gaattgtttt cctcagatta cgatgttttg
     1021 gatactctcg ataatgtatt atctgactat aaatatatgg ggaaatctgt agtagcaact
     1081 ttgggggaat aaaatgtttg actttaatga atatttatct atttccaaac aaattgaatc
     1141 agatgataaa tataattcta aagaatctta tagaagaact gctgtttcaa gagcatacta
     1201 cagtgctttt aaaaaatctg atgagtattt gaaagaaaat tatgatatta tttataatgg
     1261 aagtagcgga aaaggaagcc accaaaccgt ttggaatttg ttttcaacag ttaaggaatt
     1321 gaatacctta ggaatacata atagtgggta tagaatgtta gagaaaagaa aatgtgctga
     1381 ctatattcct aatgaaacca ttacgaaaac agatatggcg ctgatgaatc gagaagcaga
     1441 aaaaataata aacaaactca cctaatgaat ttcaagcgag tttgtttgtt atttttttat
     1501 ttaatctttg tatctttctg gatcaacgaa agtatacttt atatagtcat aacgccgatg
     1561 atcgctacgt gcgtccggca cgtcagtcac gatatcaaac aaaaagtata cacccttctt
     1621 cattctagtt ttcgcagcag gaattttgaa atagttctta ttagaatagt agagattgat
     1681 taataagcta tcttcgattg ctaaaaagaa aacttctgaa ttccatactt tataaaaatc
     1741 tttgataaat ctattcgaag ggtcaaattt aaaccataat tgtgtctcat taaaaagcat
     1801 aaccattact ccgatctgtt tttaaaatta gtttctacct ctaatatata tcgagttttt
     1861 attttgcctt cagagaatac tgtttctttt tttgcagtta caggttgttt attttcggaa
     1921 aaagctaata tagctaagat tgaaacatcc atctggaatt tatctttttt actgctttga
     1981 tcataaaagt ctgcatattc atcactgata ttttttctaa taaattcttc catcataaaa
     2041 atcacctcaa aacgattata cgaacttacg ttcttgttgt aaagcgatat ttgaggggca
     2101 aaaaaggggc ataatttgac tgatattaag ttagctattg atatatgaat gacatacaaa
     2161 aatataaaat cttttaaaaa tgcttatata tcaatgtttt tgccattctt ttatatatct
     2221 gttatatgtc aaaaaaatgt gttcaatttc aatttgtatt tgaataaaga ggttgtgaaa
     2281 aagctgtcct gcatcaagta ataagaacag ccaatcaaaa acagcttctc atgtttttga
     2341 tttggttgga cttattaccg cagatataag cttttgagca ccgtgaataa agaggttatg
     2401 aaatcaacgc tctaacctga gtattagaga aaaaaacgca aaacatatca tttatgtttt
     2461 gcgtttttta tttatctttt tttctcaata caatataaaa taggcggctg gttcttttgg
     2521 ttgataaacc gataattcag cacattatat gtttcctgtg gcagtttgga acaaaaagaa
     2581 tcaaccatat ccagttcttt ttctccacct tcatgaccat agtagacgac aaggatcaat
     2641 cgtccgcgag gcacaagtcg tttcaatatt tcttccatag ctgtgcgtgt agtctctggc
     2701 atagtgatga ttgctttatc actttttggg agatacccta gattgaaaat ccctgctttg
     2761 agattttgtt gttcagctat cacttctcct aacgtttcgt ggccttgtag aaacaatgag
     2821 acacgttctt ctaactgacg ctgttctagc ctttcacgag tagcatcgat tgcttgttgc
     2881 tggatatcaa aactatagac atgaccagtt tttccgatgt gttctgctag aaaaaccgta
     2941 tcgtggccat tgcccatcgt tgcatctacg acgtgatccc ctggttgcaa gatttcttgc
     3001 agtaatgtat ggctgaaatg caaagcagtt tgcaacatca gacgctcacc tttttccgta
     3061 catcatattt tccttggaag ctatctctgc gaagaagttc ttcatcaatt gcattcaaga
     3121 cttcccattt tttcaagctc cacattggtc caatcaagga atcccacggc gcatcccctg
     3181 tcaaacgatg gatgatgatc tcttttggta tcatttccag ctggtcgcaa atgacattga
     3241 catagtcagg acggctcatt aattgaaggc gaccttcatg atagtcccgc aacattctcg
     3301 ttttgcgcat cagatgcatc aaatggagct tgattccttg gatatctgaa tctaaaatgg
     3361 tgcgtctgac attttctttc atcatttcta aactttcgcc tggtaatccg ttgatcaaat
     3421 gcgtacaaac acggatatta tgtttgcgta atttagccac gccatctaaa taagtttgat
     3481 aatcatgtgc tcggttgatc agttttgaag tttcttcaaa agttgtttgc aatccaagtt
     3541 ctacccataa atacatccgc tcgttcagtt cagcaaggta atcaactact tcatctggca
     3601 gacaatccgg tcgtgtaccg actgataatc ctacgacacc tggtaaattg actacttgct
     3661 caaatcgttc tttgattatt tcaactggcg catgggtgtt tgtaaaattt tggaaataaa
     3721 cgatgtattg ttggacatga ggccattttt gatgcatcat gtcgatttct ttctggaatt
     3781 ggattggaag agggtcttca ggtgcaacga tcatgtctcc cgaaccagat acactgcaaa
     3841 aagtacaacc gccatgggca acagtcccat ctcgattcgg acagtcaaat cctccatcga
     3901 tcggcacctt gaaaattttc ccgccaaact catttcgtaa agcgtaattc caagaatgat
     3961 atcttttatt tccttctgaa taaggaaaag tcattaaaag tccttctttc tgtaagagtt
     4021 atctatttgt tttctttttt ctctatacac tggataagtc aggcacagcc aagaaagact
     4081 gagtaagtaa ccgccgatga tatcagtagg aaaatgaacg cccagataaa tgcggcttat
     4141 cccgacactt actataataa acatcatcag caattgaagc aatgtgcgta aggttctttt
     4201 ttgaacaaaa gctggaagca gaaatagtaa agaaccgtaa agaatcatac tgcctgctgc
     4261 atgtccacta gggaaactgt aacttgtttc aactactaag tgcgccaatg aaggacgctc
     4321 tcgcatgaaa aatagtttga tcaccgggtt gatgattcca gcaattacaa taaatccaga
     4381 aacgaaccaa aatgtttctg cccttttttt cttataccac atccataaag ccgcacaagc
     4441 aaataaaatg atgacggtaa gaggattacc gaatttagtc ataaagagtt ggtagctgtt
     4501 cagatcagga taagaagctc tgacaatgcc tgtaaaccac tgatcgaaac cagaaagcca
     4561 cgacagatgg aactttacga tccagcccaa aatgaaaaac aggacaagaa agaagctacc
     4621 agccacctga aatgatgttt tatatttcat acaattcctc ctttgaagca atgacttatt
     4681 atagcatttt tggtccagcg aaaaaaacgg taaagagata aaaccaatgt atgattcctc
     4741 tttgaataac caatattctt ataaaaaaaa taactgtaat cggaaagaca ttttttggta
     4801 atgcaaatga aatgttaggg aaataaaatc agtgtttttc gaaatccttt taaacaagaa
     4861 cgtagacgta ggaagaactt gaaaatgaac agaagttgtt cattacggta aattacaata
     4921 tgattacaaa aaacaacaaa gctcttaaat aacttttaat aaatattaag agaagttata
     4981 attattaata atagataaat tgaagttgga ggatagaaga tggaaaacat tgcaagaaaa
     5041 gaacggagac gtttagaaca gaccaaacgt tttcgaaaag caaaacgagg ggcagcaatc
     5101 gtgggaactg cgatggtagg ctgttctgtc gctgccccat tagtacagcc ggttcctgtt
     5161 caagcggatg aaacacctgt tcagttcggc gcaagaatca atacagcggc atttatcaca
     5221 gaaattgcta cttatgctca accaatcgct caagccaacg atctatatgc atcagtgatg
     5281 atcgcacaag cagttgtaga aagcggttgg ggcagtagtg cgttatctca agcaccttat
     5341 tataatcttt ttgggataaa aggcagctat caaggacaaa ccgtctacat ggatacgctt
     5401 gaatttttaa ataatcaatg ggtaaataaa aaggagcctt tccgacaata tccttctttt
     5461 gctgaatctt tcaatgacaa tgcctatgta cttagaaata cttcatttgg caacggttat
     5521 tactatgccg gtacttggaa gagcaacacg aaatcctata cagatgcgac agcttgtttg
     5581 acagggcgtt atgcgactga tcctggttac gcaggcaaat taaataatat catcgcaact
     5641 tacggattga cccaatatga tacaccagct agcggaaacg caggcggtgg agcgactaca
     5701 ggtggcaata atactggaag tgcaggtagt actggcggtt caagcaattc tggtaataca
     5761 aactcaggtt cagcaacttc gaccacttat actgtccaat ctggtgattc tgtttgggga
     5821 atctcaaata aattcggtat cacaatggat caattgatcc aatggaacaa catccaaaac
     5881 aatttcattt atccaggaca aaaactgaca atcaaaggta gccaggaaaa tggctcttcg
     5941 acgaataatt ccggtaacaa taccaattct tcaggaaatg ctggtacatc aaacggagga
     6001 caaacaactg gtgcgaaata cactgttcaa tctggtgatt ctgtttggaa gatctcaaat
     6061 gatcacggaa ttacgatggc tcaattgatt gaatggaaca atatcaagaa caatttcgtt
     6121 tatccaggac aacagctaat cgtatcaaat ggcggttctt ctaatgctgg agcaaatact
     6181 ggctcaaata ctgggaatac aagtggctct agttcgtcca gctcaagttc ttctaataca
     6241 gcttcaggaa cgaaatatac agttaaagcc ggagactctg tttggagcgt ctcaaataaa
     6301 tacggaatta cgatggctca gctaatccaa tggaacaata tccaaaataa ctttatctac
     6361 ccaggacaac aactgactgt ttcaaacagt ggatcaacaa acagcacgtc aggtaataca
     6421 ggttcgtcaa ccaatacaaa taacagcagt tcagttaata ctggcagcag ttcgtctcaa
     6481 ggcacttata ccgtgaaagc aggtgaatct gtttggagcg tggcaaataa aaacggcatc
     6541 acgatggatc agttaatcga atggaataat atcaaaaaca acttcattta tccaggacag
     6601 caattgatcg ttaaaggtgg aacttcggca aatacaaata caggttcaac tacttctgca
     6661 gcgaaaccaa atacaccgaa tacgtctgct acgacaagta catcatccac tggtaatacg
     6721 atgtataccg tgaaagcggg cgagtcagtt tggagcgtag cgaacaaaca tcatatcacg
     6781 atggatcagt taatcgaatg gaataatatc aaaaataatt tcatctatcc aggacagcaa
     6841 gtgattgtga agaaaggttc atctcaatca acaaaccaac aatcagttac tggttcgaaa
     6901 acctatactg tgaaatctgg agaatctgtt tggagtgttg ctgacagtca tggaattaca
     6961 atggctcaac taatcgaatg gaacaatatt aagaacaact ttatttatcc aggtcaaacg
     7021 ttgattgtag ctaaataaaa tagctgttcg aagaaataac gattgaattc cacaaaaata
     7081 tttgttacta taaggctact taaatatgac aacacttgaa aaggaagtag taaaaagact
     7141 gaagtttcag agagcgcatg gctggtgaga atgtgcacgg atgcttttga actcgccttt
     7201 gagttgccct tgctgaatac ccgagtaagc aagcggcggt gacggccgtt acaacgttcg
     7261 aggccttttc actaaggtaa aattaggtgg taccgcgtag attacgtcct ataaaaagag
     7321 caatcttttt ataggatttt tttatttctt ttgtgaagtt tgagaaaaca aagcaaaagg
     7381 aaataaaaat aaacagattc tgccggtttt ttcgttatat ttataataga aacaagtgtt
     7441 ttcaatagaa caggaggaca gcaaatgagt tacaatcata aagaaattga gaaaaaatgg
     7501 caaaaatact gggcaaaaac gaatactttc aacacccatg atgatcctga aaagccaaaa
     7561 ttttacgcac tggatatgtt tccctatcca tccggtcaag ggctacatgt agggcatcct
     7621 gaaggttata cggcaacgga tatcctttca cgtgtgaaaa gaagtcaagg atacaacgtg
     7681 ctgcatccaa tggggtggga tgcattcggt ctgcctgctg aacaatatgc gctagataca
     7741 ggaaacgatc cagctgagtt tacccaaaaa aatatcgaaa cattccgacg ccaaatcaat
     7801 tctttaggat ttagttatga ctggaatcgc gaagtgaata caactgatcc ggagtattat
     7861 aaatggacac aatggatctt tacgaagctt tatgaaaaag gtctagctta tgaagcagaa
     7921 gtagcggtaa actgggtacc tgaattagga acagttattt caaatgaaga agtgatcgat
     7981 gggaaaagtg aacgtggtgg ctatgatgta gtcagaaaac caatgcgcca atggatgctg
     8041 aaaatcactg cttatgctga tcgcttattg gatgatctag aattagttga ttggccagaa
     8101 agcattaaag aaatgcaaag aaattggatc ggtcgttcag taggagcaaa tattgaattt
     8161 aaagtggctg gtacggataa atcctatacc gtatttacga cacgaccaga tactctattc
     8221 ggtgcaactt actcggttct tgcacctgaa ctagatcttg ttagagaaat tacgacccct
     8281 gaacaaaaag ctgctgtaga agcttatatc gaagagacag ctaaaaaatc agatctaaag
     8341 agaacggatc ttgcaaaaga aaaaacagga gtatttactg gtgcttatgc aatcaatcca
     8401 gttaatggca aggaaatccc aatctggatc gccgattatg tattatcttc atacggcaca
     8461 ggagccatca tggctgttcc agcacatgat gaacgtgact ttgaattcgc tcaaactttc
     8521 ggactagaaa ttcttccagt tatcgaaggt ggagatgttg aaaaagctgc ttacacagaa
     8581 gatggtacgc acatcaactc tgaatttcta gacggcatga acaaacaaga agcaatcgat
     8641 aaaatgaatg aatggctaga agaaaatggc gtagggaaaa aagaagtcag ctatcgctta
     8701 cgtgactggc tattctcccg tcaacgttac tggggtgaac caatcccaat catccattgg
     8761 gaggacggaa cagtcacagc tgtcccagaa gaagagctac cattacggtt gcctaagaca
     8821 aaaaacatca agccaagcgg tactggagaa tctccattag caaatatcga ggagtgggtc
     8881 aatgtcgttg atcctgtaac aggtaaaaaa ggccgtcgcg aaacgaatac aatgccacaa
     8941 tgggcaggaa gctcatggta ttacctgcgt tatatcgacc ctcataacaa aaaagaacta
     9001 gcagattatg aaaagttgaa gcgttggcta ccagttgaca tctacattgg tggagcagaa
     9061 catgcggtac ttcatttact atatgcacga ttctggcata aattcttata cgatatcggt
     9121 gttgttccta caaaagaacc attccaaaaa ctatacaatc aaggaatgat cttaggcgaa
     9181 aacaacgaaa aaatgtcaaa atctcgtggt aatgtagtca atcctgatga tgtggtcgaa
     9241 acttacggtg cagatacact gcgcatgtac gaaatgttca tggggccatt agatgcttcg
     9301 attgcttgga gcgaaaatgg cttagaagga agccgtaaat tcttggatcg tgtatggcgt
     9361 ttgatcgttg atgagaacaa taaaatgcgt gaccgtatca ctacattgaa tgatggcaag
     9421 cttgataaag tgtatcatca aacagtgaaa aaagtgacag aagactatga aaatcttcat
     9481 ttcaatacag caatctccca attgatggtc tttatcaatg aagcctataa agtggacgct
     9541 ctgccttatg aatatatcga aggatttgtt caactactcg caccgattgc tcctcacatg
     9601 ggtgaagaac tatgggcaat ccttggaaat gatggtggta tttcttacgc accatggcca
     9661 acatacgatg aagcagcact tgttgaagac gaagtagaag ttgttttcca agtaaacggt
     9721 aaagttcgtg cgaaaagcaa tgttccccga gacttaggaa aagatgagct agaaaaagca
     9781 gcattagcca atgaaatagt gcaagaatat attgaaggca aaacagtcag aaaagttatt
     9841 gcggtaccaa acaagttagt caatatcgtt gctaattaat tggctctttg tcaataagga
     9901 ctgatgagtt gtgcaaaatc aaatctgggc cagaatgaac ttcattctgt ctcagatttt
     9961 ttgttatttc aaattgatta attgattgat caaaaaggtt ttgattttca tgttctcaaa
    10021 cacgttcaat gtctttttct tctgaatggt cttgtaagag atctctgtaa tcatcaaatt
    10081 tttgtctatt aatcttagta ttttttgatg tataaactac ctgaaattga gagtacatac
    10141 caaattcata aattttttat tagtgggact agtgattgta tggattttga cgcataatga
    10201 atgaagtatg agaaaaggag agacaaatgg atcaagaact atttattatc gaagtattat
    10261 cagctaaaca aaaaattatc gagaaagcga aaaaaagagc gaaaagaata atgttcaagc
    10321 ttttaagctt agtatttttc tctggtttgc tttttttcgg agctgtatcg ttcctatatc
    10381 gccatatgag tgcagtagtc cgttcagctg aagggatgca aaaattaaat aatttgtatc
    10441 acttttcgtg gggagttggc ggaataacaa ttgttgtgct tattgttttt cttctactta
    10501 tttggctccg ttaccatcaa ttgtcgcgtc atttcgatca atggcttagt caaagagcac
    10561 aacagttttt acataataaa ccaacttctc aagatgatga ctatctttat tttgagaaga
    10621 cttcgacgag tcaagctttt cggatacaaa aaagtgattg ccagttattg ctgagatcac
    10681 ttgatgattt acctatctac ttaggcgaaa gcaaatcaaa attcggaatg aacacattcc
    10741 atattttttt actagaaaac gaacccagat gggaaaaaag ccagtcttcg cctggtggat
    10801 acctgacaac taagatgagt acattagtca ctggtttttt cctcattctt ttagctggaa
    10861 caatctatta tgggagatac actcagccaa aaatgtcttc tcatataaat gctgcttctc
    10921 acatgacaat gaactcaact aacgatacgc atatacaaaa gacaaatgaa gggttgttag
    10981 ctgatcctaa gcaaaaggta aatttgacaa cacaaaagat aaatgatctc aaacttgata
    11041 cagagacgca ctctctctat atgacaacag atagtggtgc taattgggta tttgtgccga
    11101 ttgattcgca atggttgcgt tttggcgaat acaccctgac aacggggctg attcctgaag
    11161 gttattggat ggacaacaca tatgatattt ccgccgattt ctcatggttt atctattctt
    11221 ctggggatga tgtacgtctg ctgacttcaa gagataatgg taaaacatgg caaacgtcta
    11281 ttatcaccca atcagttcag ccgatacgtt atcgaaaagc ggtattttat ggcaacgatg
    11341 gtctatttat ctgtacatca gccagtggga tgtctgcaga aactttgtac atttacacta
    11401 ctatggatgg cggaatcact tggataaaaa gtggaagtac aatgatcaat cagccagtac
    11461 aaaatgtcag cttcgttaca acttctttag gttttgtttc gacacgtgaa agtttgtttt
    11521 atacaaacaa cggaggacgc tcattcaaag aatcagttct gtcgattccg gaaaactatc
    11581 agacaggggg gatagatctt tttcaatcac caaatgaagt tactcaaata agcgcgaata
    11641 cgttagagac aaaattttat ttgttgaaaa aaggaccaat cgatgcaggg aaaatgtttg
    11701 cctgcctctt ccgttcaact gataacgggg aaacatggca attcgttcag caactatcgc
    11761 aagtagaaca aggagattaa agaagagaga ttgtgagcct gacgttcagc accgagtcac
    11821 aagaaacaaa ttcaaaaaac agcttctcat atttgttgaa tagtgtaact cgtgattcgg
    11881 agttgacaag agcaacaaga agcgattttg aagtatagct tctcgtattt tacaagatcg
    11941 tgtcttattg ccgataggtt gtctcttgaa caccgtttat tcgtaaaaag ggattgtgac
    12001 aagtcttttg tcactactta ccgaacgaaa ctgaaggagc tatccaaaaa gtatcattag
    12061 tattattctt tgtgtttcta gtggcaccac tagtacattt aaaaaagcta tcgatcatgg
    12121 actaatcata catgatcgat agctttttag ataatgtttg ttacgctatc tgaaattgac
    12181 tattataaag actggcataa agcgttggtg attggagtag ttcagaatgt gttccttttt
    12241 cgacgatatc gccattcttc attacaagga tcatgtctgc attttcaatc gttgacaaac
    12301 ggtgtgcaat cacaaaactt gtcctatctt ttgtcacagc ttccattgct tgctgaatca
    12361 atgcttctgt tcgtgtatct acgctagaag ttgcttcatc taaaataacg acaggaggat
    12421 tcgctagaat gactcgagca attgtcaata attgttgctg tccttgagat aacgtgccgt
    12481 tttcgctaga aatgatcgta tcatatccgt ctggcagtgt tcgaataaag tgatcacatt
    12541 gtgcgatttc agccgcttcg ataatttgtt ctcttgtggc atccattttc ccgtaggcga
    12601 tattatcagc taccgttcct tcaaacagcc aggtattttg taaaaccatc ccaaaagaac
    12661 gacgtagttc tccacgtgaa agcttggtaa tatcaagacc gtcgaattcg atctttcctt
    12721 tattcagttc ataaaaacgc atcagcagat tgactaaagt cgtttttcct gcaccagttg
    12781 gaccaacgat cgctaccgtt tgttttggct ttactgaaaa atcgacttga ttcatcaata
    12841 ttttatctga tgtgtaacca aactgtacat ttttgaaagc tatttttcct ttcggttgtt
    12901 ctaaaagtct tgcatctgga aggtctggaa tttcatctgt ttcatctaat atctcaaata
    12961 tcctatcgat tgctgccatt gcggattgga tcgagttgat cacataagaa gcggtagaaa
    13021 ttggttcaga aatctgattg atgtactgaa gataagcttg taagaagccg atcgtcacac
    13081 cacctgatag aacaagcata gcaccgaata ccgcacttat gatgaaggcg agttgattaa
    13141 tgaaacgaat ggccggatag atagcacagt tcataaattg agcacgttta aaagcgttgt
    13201 attgcttttt atttacttcg tgtatagcag cttctgcatg agcttgctga ttgaatgttt
    13261 tgaccactag attaccagct aagatttctt ccattcgatt atttaaaaca cccagttcat
    13321 actgattctg ttcagaaatc tgtttgtttt tgttcgcaat cttagttgta acaattgaac
    13381 tgccaacgat cagcaataag acgagcaaag taagcttgct ttcgatataa aacagcatca
    13441 gaccagcagc agctattgtt acgacagaag taaaaaattg attgatacct gtcaataaca
    13501 cttgagaaag ttgattgaga ccggtagttg tccgactaat gatgtcacct acttgatgat
    13561 tgtcaaaaaa cgacatcggt aatgttttga atttttttgt gatttctttt cgcaccctca
    13621 atgtgatctt ttcgcttaac gctgccattg tccgttcctg aataaatgaa gtgatgctgc
    13681 ttaagactga acagccgatc agcaataaga cagggaacaa caatgcttgt ttgatatcac
    13741 tgaaagaaag ctgtccaata cctgtttttc ttatttctga taagagatca tcgatcccga
    13801 ttcccatgat caagggcatg gctacgacta ataggttccc gaataaactg catagaaaca
    13861 atccgtaaaa atatttatgt tcaggtttga tcattttcca aaaacgtatc aaagcacgcg
    13921 tgttcaacgt ttttttcttt tccatcgtat cccttctttc tatattcctt gtgattttgc
    13981 aaactcctga taagtttggc aattagacag tagttcttca tgagtacctt gtccaacgat
    14041 ttttccttca tctaaaacaa tgatgttatc tgcttgttgg attgtactga ggcgttgagc
    14101 aacaatcacg agagttttct ccgacatgtg tttatgaagg gctgctctta atgctgcatc
    14161 tgttttatag tctaaagcgg agaaactatc atcgaataca tagatctctg ctggtttgat
    14221 caacgctcga gcaatacata tccgctgttt ctggccccct gaataattag aaccgccttg
    14281 agcaacaaag ctgtccaatc cgtcaggaag ggtgtccact agttcttcta attgagcgat
    14341 cttgatcgct ttagacaact cttctgttga ggcatattca tttcccatct gcaagttgct
    14401 taaaattgtc ccgctgaata agaaagcctt ctgagggaca taactgatgt gggagcggat
    14461 ctgttcttga gtcatttgag taagaggaat accaccaagg gttacttttc ctatcgtagg
    14521 gtcactaagt ctcaagagaa gtttcgccaa actacttttt ccagatccgg tcccgccaac
    14581 gatcgctgtt gtttttcctt taggtattgt gaaatcaata tcttctagaa ctggatcaga
    14641 gatttcagta tatttaaatg tgacatgttc aaaagcagct gcatttgtct gatcaaaggt
    14701 tggttcagct actgttttga tcgtctcttc ctcaatttcg atctctgctt gcagtatttc
    14761 ttctatccgt cgtaatgagg caaacgattt agggataatg accaatacca tagctgcgat
    14821 catcaagtaa gcaagtgtca gcatagagta ttcgactaca gcagtcacga caccgatttg
    14881 taatgctcct tctgctacaa gatttccgcc aaaccacaaa atagaagcat aaacgattcc
    14941 catgagcaaa aaagcaattg gagtgaccca agcaaatatt cggttcactt tgatcatttg
    15001 attagcatag tcagcaaagc tcttattcgt tcgcttttct tcatatgatt gattatcaaa
    15061 ggcacggatc atattaatcc cagtaaagaa ttctctcaat gtgatggtga tccgatccat
    15121 ttttggctgg atactcaaag ataaaggtgc ccctcgtttc atcagtcgat aaacaatcca
    15181 tacataaaaa acaacagaga tcaatgtaac ccatgttagt aatagagaat aacgaaacat
    15241 catgagaatg gtgaaaacgc aaataaccgg tgctggtaag atcatttggc aaaataaaac
    15301 aatcatttgc tggacattat cgacatcatt cgtcattctt gtcaaaagag atccagaact
    15361 aaaacgactg atatccttca ttgacagctg ttggaattta cggaaatatt tctcccgcgt
    15421 ttggaatcca aacctagcgg aagccaatgc tgaaaagtaa ctagaggcaa ctgcagcgat
    15481 tgttcctaga aacgctacaa gcagcatttc aactccaatt ttttttataa ctgaggcttc
    15541 gccacttgct atacctgtgt cgatcagctt tgctactaat tttggtacac ctaatgtacc
    15601 ggcgatttct aaacagatca tcacaaaggt aaggagagcg agtcctttgt ttttctgtaa
    15661 gaatgttttt aagatagaca tattattcct ccttttttcc tgatactttt cgattctata
    15721 ccttcaagta acttgaaggt caatagaaaa aagaataaac tgaaaaagag gtgagaaaaa
    15781 atgaaaaaaa tgtatacgat tggccaagta tcggaactat ttgatttgcc aaaatcaacg
    15841 atccgctatt gggatgaaca aggattaatc cgttcaagta gacaagaaga gaatgattat
    15901 cgattgtttg atatcgatga tatttttatg ctttatgata tcgtttttta tagaaaatta
    15961 gatataccga tcaaacagat gaagaattta tatggaaaaa cattgacgga gttatatgag
    16021 acacttgatg aaacagaaag aagaatccat aaagaactgg tggtgatgaa acaaaaacaa
    16081 aaagagataa gggagcaaaa aaaacagttg aaattgatga tcgatacaaa cgaggaagaa
    16141 tttcctgtag aagagatccc ttttgactgt atgatctcaa cggagtttga agatattgtg
    16201 gaaatcaaaa aatttctacc taactattca agctttggga tgatgagtat gccagcttcc
    16261 agttcacaga cgatgtatgg attttttatc gaccctagtg aagtacattt atttactcaa
    16321 gacgtgattt gggagaaaaa agatacggct gtttatcgtc gattcttatt gaaatccgag
    16381 atgaaccatg cggaacgtaa taatatttta gaaatcagag aaagaatgta tgaaaaagga
    16441 tggaaaacag gagaagtgat cggccagtat ctattgacga atacggatga aaacaatatc
    16501 agaactgaat attatcatgc atggatagaa atgaaaaaat aggaaatatg tgtttaagat
    16561 aactcgaaaa tgatggttgt tttagttata aagaaaaatt ttctggttcg attacgggtt
    16621 taatgtgggg gattattagt cgtggataga tagaatttta gttttttaga ggaaatatgt
    16681 ctttaaaaat ggaatggttg caattcttag cgatatatac gatgtaattg tcctcttaaa
    16741 aaagtatgga aaaataattg tattgggtgt tatgtataat tcatggtgaa ctgagactaa
    16801 tgagaagaaa aattcatatt gttatgagtg agattgtatc agatgagaat gataaattaa
    16861 ataggtgcat aaaagcatta cacttaaaat acattgttgc ttacattatt acaatatgtt
    16921 aataaggcaa aaataaatag atggattgaa taaacatatt ttttaatcaa atagtcccta
    16981 ctgtgacttt cctcagctat cggtgatact accgatagca tttttttgct tataaaataa
    17041 ttataagtat ttagagattt ttcttctaac attcttcaaa caagaaaaat cacaaaggtt
    17101 attgttattt ttatatattc tttttaagaa tgattgtttt tttatagaaa ttttaaaaaa
    17161 taaaacacgt tattgatgga tagttagttt gttatttggt aatattatag aagttgactg
    17221 gtagtgattt atttttcgtc gttttataaa aatgttattt tttggaaaaa ttcacaaata
    17281 tgtaacgaat gtttttctgg aatttgctgt gttaaaaagc agtatgacta atataaatac
    17341 tattgtcatt tatgcaattt tttatggata gtaattttag aggggaatca atgaaggaag
    17401 aatagaaggg aaaaatagtt gcaaatacgc cagttagcaa aaatagcaat acatcttcaa
    17461 gctttaaaat tcgagagaat catcttggta gtggaatcaa ctacaacaaa aggattaaac
    17521 caattaatag atagaattac caatggaaaa atagaaaagg tagttattct atacaaaagt
    17581 tgtttaattc gcttcggtta tgaacttagt gaaacccttt gcaatatatg gtacagaata
    17641 tagaaattat tgacattaca gaaaatgatg aagatttaat acagattgtc actatttgta
    17701 gatacctttt acaaggaaac cgagccaata aagctaagaa gatgattaag gagttgatgg
    17761 aagacgatac aagttaagaa agtgaaacta cgcccaaata aagagcaaaa agagtaattg
    17821 gacgtggaaa atgcaagaaa tgaaccatcg attcggtgga cagtttatta gtaatgacgg
    17881 tttgagaaca tccatgacga gaatgaagga acatcctaaa tgcgtttagt tgaaccaagt
    17941 gccaaataat atggccaaat aagcgatcag ttatcgatga atcccaagta ttctaaacta
    18001 tatattcatt ttgatgctaa gcattgatat atttttttgg gattgatgaa ggttaaccaa
    18061 tacagggact cactgatgaa attctagagt ctgaccttgg tatcaacgat ttagtgattg
    18121 tttctaatgg aaaagtataa aagtatataa gtacattaac aaaataacta ttagggttac
    18181 gctccagctt gtgcaaggca ctggcaggag gaatcgtgaa atcataatta tggttaagcc
    18241 acacggacaa ctaaaagtca tacaaagcta tcgaatcaat caacagaaga caatcggcaa
    18301 tcattagctt tgtttacagc ttacattgca acgcttgagt tgaaccgaaa atacgaggga
    18361 ggtaacgcag ccattttgag ttggggaatc tttttagaaa attatcgggt accttgttgt
    18421 ttagtcaaaa ttataagggg gagtaatagt gaggaacaaa tttcataaac tgttaagtat
    18481 gtttctagtt atgcttattg tgatcaatca atttgggaac ataacggttc tagctgagtc
    18541 tttagcagaa cagccagagc gttcgctgac gatcgaagtt gatcaagagg aggctgcttt
    18601 gggtgagcag ttccagttgc gagtcagagg aacaccagac ctgctaaatg cattggtcat
    18661 tgataagagt gaggatttga ttgaagggga agtgaagcaa ctcaatgatt acgaacgtct
    18721 gattacttat tcttcccagc attcaggtaa atacgaattg accgcaagaa gcggtgatat
    18781 tcaatcaaat acggtctcaa tagaaatcag tgtaccagaa gaaagcacaa gtgagtcttt
    18841 taatgtacca gaagaaagca caagtgaatc ttttaatata ccagaagaaa gcttaagtga
    18901 atcttttaat gaagccagat catctgagcc atctataacg caggaatctc agattgaaag
    18961 acaagaggag ctcttgaatt atgacatcgg catctctgct gagcgcccca ctttgccgag
    19021 caggcataca caaacgttaa agggatacat tcaaggaggc gctggcgata ttcttgaaga
    19081 atatggggag atggtcgtac gagttcctag agcatcgatt ggcttaattg agttcattag
    19141 agtggaggtc gctgatgatt cacctttaaa gccactggca ttttaccaag aaggcacaga
    19201 cgttgttttt ccatttacct ttgattatga aggattaaat gaagccgctc agtcgtatac
    19261 attcagtatc acgtttgaag ttgctttctt tcaatcaggc ggtactgagc caaataatga
    19321 ctttcaagtg agtcttactt atgctgagcg agcagcaaac acggaatttt caattacgcc
    19381 tattccttca tcaagaccca ttttttcgaa attatactat ggctctagag aaatcgacag
    19441 ccaaggaaat cttgggaatc tgctgattga cgggcaagac gtgaccaaca gtaataaatt
    19501 tattttgcag gtaaattatg aaggatcacg aaaagacggt gtagtggtta ccgatgtact
    19561 accgcaagga acaactttgg caccgaatcc gactacatgg agttccactg gaaatagaga
    19621 acctatttca ggtggggttc ggatcgcaga agtaacgaat ccaggtgaag caaacgttag
    19681 aactcattat gtttccgagg aatttgtgga caaagtatct tttaataagg aaacgaatac
    19741 acttgttgtg gactttggta atctagcaga gggtcaatcg tattttattg aatatgctct
    19801 tgaagtgacc gatgtcgact tgttcaatga aggaagacaa gaggatgggt tttctcggaa
    19861 tcgagcgagt atgacctaca ataatcaggt aatgagccga gactaccgct tgagaatccc
    19921 tgaaagtaat cttccggcaa tctctttaag aaaaagtgtg gacaaaaatg ttatcaatct
    19981 caatgaaaat gaactaacgt atactctgca tgtctcgatg ttttctggaa caagaaatac
    20041 gcttgttatt gaagatgttt tggaagaagg catggaattt gtgtcatttc tatcagatat
    20101 tccctctttc attgatgccg aagtcaataa tggaatagtt cgtttcagtg cgaataatac
    20161 gattggtggt ccgacaagtt ttaccctctc ttttaaggtc aatgtagagg cgtatgcggt
    20221 cggcgatcaa attttaaact ttgcaacgct tgtgaatagt gacaatcgat tgaatacgag
    20281 tactgtaaga acaaggaaaa tcgatgggcg tattaaagta attaaaactg atgagaatgg
    20341 ccaaaggctg gcaggagcaa aatttgaaat tttatcaagc gattcacaag tgatacaaga
    20401 aggtataacg gcagaaaacg gagaattttt aagtgaaccg cttcctgtag gtagctatca
    20461 agtccgagaa acagaagcac cggaagggta tcttttagat gcgacggtac atgatgtttt
    20521 tataaatgaa tactccatag aagaagtgac gttaaccatt gaaaacatcc ttgatacggg
    20581 tggtgttgaa ctaattaaac atgctgaagg cagtggtgaa gtccttcaag gagctgtttt
    20641 tgagttacag aaccgagaag gagaaacgct acaaaccggt
//
LOCUS       DBBGSP010000051        20608 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000051 DBBGSP010000000
VERSION     DBBGSP010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.051"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            112..306
                     /locus_tag="ACIZE9_002209"
     CDS             112..306
                     /locus_tag="ACIZE9_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094053.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            575..874
                     /locus_tag="ACIZE9_002210"
     CDS             575..874
                     /locus_tag="ACIZE9_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094054.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(971..1405)
                     /locus_tag="ACIZE9_002211"
     CDS             complement(971..1405)
                     /locus_tag="ACIZE9_002211"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6094055.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1637..2347)
                     /locus_tag="ACIZE9_002212"
     CDS             complement(1637..2347)
                     /locus_tag="ACIZE9_002212"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGC6094056.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2337..3197)
                     /locus_tag="ACIZE9_002213"
     CDS             complement(2337..3197)
                     /locus_tag="ACIZE9_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGC6094057.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3202..3840)
                     /locus_tag="ACIZE9_002214"
     CDS             complement(3202..3840)
                     /locus_tag="ACIZE9_002214"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGC6094058.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3855..4154)
                     /locus_tag="ACIZE9_002215"
     CDS             complement(3855..4154)
                     /locus_tag="ACIZE9_002215"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6094059.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4197..5681)
                     /locus_tag="ACIZE9_002216"
     CDS             complement(4197..5681)
                     /locus_tag="ACIZE9_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGC6094060.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5701..6162)
                     /locus_tag="ACIZE9_002217"
     CDS             complement(5701..6162)
                     /locus_tag="ACIZE9_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6094061.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="ACIZE9_002218"
     CDS             complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="ACIZE9_002218"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGC6094062.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7465..8235
                     /locus_tag="ACIZE9_002219"
     CDS             7465..8235
                     /locus_tag="ACIZE9_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGC6094063.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8508..9335)
                     /locus_tag="ACIZE9_002220"
     CDS             complement(8508..9335)
                     /locus_tag="ACIZE9_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094064.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9903..11138
                     /locus_tag="ACIZE9_002221"
     CDS             9903..11138
                     /locus_tag="ACIZE9_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC6094065.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12137..12397)
                     /locus_tag="ACIZE9_002222"
     CDS             complement(12137..12397)
                     /locus_tag="ACIZE9_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HGC6094066.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12424..13725)
                     /locus_tag="ACIZE9_002223"
     CDS             complement(12424..13725)
                     /locus_tag="ACIZE9_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6094067.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14017..14475)
                     /locus_tag="ACIZE9_002224"
     CDS             complement(14017..14475)
                     /locus_tag="ACIZE9_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HGC6094068.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14488..15819)
                     /locus_tag="ACIZE9_002225"
     CDS             complement(14488..15819)
                     /locus_tag="ACIZE9_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HGC6094069.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15830..17272)
                     /locus_tag="ACIZE9_002226"
     CDS             complement(15830..17272)
                     /locus_tag="ACIZE9_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6094070.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17259..18023)
                     /locus_tag="ACIZE9_002227"
     CDS             complement(17259..18023)
                     /locus_tag="ACIZE9_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HGC6094071.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18127..19002)
                     /locus_tag="ACIZE9_002228"
     CDS             complement(18127..19002)
                     /locus_tag="ACIZE9_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGC6094072.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19257..19341)
                     /locus_tag="ACIZE9_002229"
     tRNA            complement(19257..19341)
                     /locus_tag="ACIZE9_002229"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19305..19307),aa:Leu,seq:caa)
     gene            complement(19359..19430)
                     /locus_tag="ACIZE9_002230"
     tRNA            complement(19359..19430)
                     /locus_tag="ACIZE9_002230"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19396..19398),aa:Gln,seq:ttg)
     gene            complement(19440..19512)
                     /locus_tag="ACIZE9_002231"
     tRNA            complement(19440..19512)
                     /locus_tag="ACIZE9_002231"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19477..19479),aa:His,seq:gtg)
     gene            complement(19574..19658)
                     /locus_tag="ACIZE9_002232"
     tRNA            complement(19574..19658)
                     /locus_tag="ACIZE9_002232"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19622..19624),aa:Leu,seq:caa)
     gene            complement(19679..19749)
                     /locus_tag="ACIZE9_002233"
     tRNA            complement(19679..19749)
                     /locus_tag="ACIZE9_002233"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19715..19717),aa:Cys,seq:gca)
     gene            complement(19795..19866)
                     /locus_tag="ACIZE9_002234"
     tRNA            complement(19795..19866)
                     /locus_tag="ACIZE9_002234"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19832..19834),aa:Gln,seq:ttg)
     gene            complement(19878..19950)
                     /locus_tag="ACIZE9_002235"
     tRNA            complement(19878..19950)
                     /locus_tag="ACIZE9_002235"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19915..19917),aa:His,seq:gtg)
     gene            complement(19953..20026)
                     /locus_tag="ACIZE9_002236"
     tRNA            complement(19953..20026)
                     /locus_tag="ACIZE9_002236"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19992..19994),aa:Trp,seq:cca)
     gene            complement(20033..20113)
                     /locus_tag="ACIZE9_002237"
     tRNA            complement(20033..20113)
                     /locus_tag="ACIZE9_002237"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20077..20079),aa:Tyr,seq:gta)
     gene            complement(20115..20190)
                     /locus_tag="ACIZE9_002238"
     tRNA            complement(20115..20190)
                     /locus_tag="ACIZE9_002238"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20155..20157),aa:Phe,seq:gaa)
     gene            complement(20226..20298)
                     /locus_tag="ACIZE9_002239"
     tRNA            complement(20226..20298)
                     /locus_tag="ACIZE9_002239"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20263..20265),aa:Asp,seq:gtc)
     gene            complement(20308..20380)
                     /locus_tag="ACIZE9_002240"
     tRNA            complement(20308..20380)
                     /locus_tag="ACIZE9_002240"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20345..20347),aa:Val,seq:tac)
     gene            complement(20396..20467)
                     /locus_tag="ACIZE9_002241"
     tRNA            complement(20396..20467)
                     /locus_tag="ACIZE9_002241"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20432..20434),aa:Glu,seq:ttc)
     gene            complement(20482..20571)
                     /locus_tag="ACIZE9_002242"
     tRNA            complement(20482..20571)
                     /locus_tag="ACIZE9_002242"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20535..20537),aa:Ser,seq:gga)
BASE COUNT         6508 a         4314 c         3269 g         6517 t
ORIGIN      
        1 aaaactttca aattgattct ttttatttat cataaagata tagatacata atcattttca
       61 cttacatata tttgaatatt aactaaaaac agcaagaaag aagaggatca aatgtattat
      121 gtagaagtaa aaacaaaagg cgtcaaaaac aaacaatatg tgaaaggtat cagtaacgaa
      181 tatcctttac ttggttcatg gaaagaagct gctccttttt ccaaaccatg tgccataaaa
      241 ataaagaacg agctagaaaa agaactgact tgtggtaaag ctgttgtaga tatcatcgaa
      301 aagtaaatcc aatgtataga aaggaagatc acacatgaaa agcgacgtac aaattgctaa
      361 gattatagaa ttagaagaag aagacgcagt gttgacaatt gaaaaaaaat aaatgtttgt
      421 ataccatatg attatttcaa tatgtatcct ggaattggag atctcgtaga gctatatcaa
      481 gatgaatcaa atatacttgt cattcatcat gaaatataga gacttataaa attgtttatt
      541 tttataatgt atcagtatag aaaggaaata aaacatggat tatactgttg aatttgacag
      601 tgaactactt aagcaatttc cacaagaaga acatttcatg tataaagaag caatttccca
      661 caaagtgaca gagtatttgg agcataattt ttttcgtata aagccagtgc gtactcgttc
      721 ggcaaaagga atatacgaga tgaaagtcaa aattaataaa aaaaattatc gcatagcatt
      781 tgctttaaaa aaaaatcatg tgttcatttt ttatattagt tcgaatttgc aaaaaattgt
      841 atttgataaa gaggtgagta aaaaaataaa atagctgagc attggaggat agattgagtg
      901 atactaagtc tatcctcttg tttttctaaa gaactaagct agaatttttt cttttgtacg
      961 ttattatatg ttatttgtca ttaccaaaaa gcaccttttt tcttctagta tctatgacat
     1021 aagaaatacc acccatttcc tttacttgaa caaatcctac tgattcataa aatttttttg
     1081 ttttctcagt atcatctgtc aataattcga tttggactgg tccataacta gtgatcttct
     1141 ccaaagcttc attcaaaagc actttgccta ttccttggcg ctgatacctc ggatgaatga
     1201 ggatatcttg aataaatgcg atcgtcgcaa aatcagtgat ccaacgaacg attccgataa
     1261 tcttcccttc cccattacgc tttatcagag attcagattg ttcaaatgct ctagctaacc
     1321 ttgcagtgtc ttttgtgtaa ttcgtccaac caacgctctt atataattca gaaatctcat
     1381 cgatcataag ggaatcaata ttcatttttt tcttcctttc ttatacaatt ctccctctaa
     1441 taatacagtt ctttgactat ttaatctatc acatataact ctcctgtaaa gattctctcg
     1501 attccttaaa attcctcttt ccttttagaa tgcatacttt ttgataaata aaaaggttgt
     1561 gataaatttt cttcacaacc tctgtttctc tctatcaagt gttatctttt aattttctac
     1621 ccttacccta gcatctctat tgcccgtagt atgcatactt tccatgtttg cgaaaataat
     1681 gtttatctag taaatattgc gggatttcac atatattggg gttgatcagc tcgttttctt
     1741 tggccatcag acaaatttca tctaagatca aactgttttc tactgctttc ataggtgaat
     1801 ccccccatgt gaacggtcca tgtccataga caagtactcc agggacttcg tttggatcta
     1861 attttctttc cttaaacgtc tcgacaatca cattccctgt atgaacttcg taagcttctc
     1921 ttacttcttc tttcgttaat tggcgtgtac aaggaacctt accataaaaa gcatcagcat
     1981 gagtcgtgcc ataagctggc aaatcgcgtc ctgcttgcgc ccacatgacg gagtgcgtgg
     2041 aatgagtatg agtaatagca gttatatctt caaaagtttg atacaaaaca acatgtgtgg
     2101 ggagatctga agatggtttt aagctatctt cttctattat atttcccgac aaatctgtta
     2161 ccaccatttg atctgcttgc atgcattcat atctgacacc gcttggctta atgacgatga
     2221 ctcctagctc acggtccact tcactcacat tgccccaagt caatttgact aatccgtatc
     2281 gcggcaatgc cagatttgct tcaaggacac gttgcttcat tgctgcaatt ttttcttcac
     2341 aagacatcat agccagcctc cttcaattta gaacttaagt agtcttttgc ctgctggatt
     2401 tctcttcgaa agtcttggct tttttcactc cacatttcaa tcagaaatgt tccatcataa
     2461 tctagacgtt tcaaatgtct taataatcca agaaaatcaa cacaaccgct accaaaagga
     2521 acatcacgaa actggcctga atattctttt gttacagggt aagtatcttt taagtggata
     2581 gcagtgatat aatcgatccc tttctcaagt tctcgagccg gattattttc cggccatgcg
     2641 gacaaattgc ctaggtctgg atatacttgt agaaaaggtg aatgaatctg ttctttgatt
     2701 tctaaaaatt ttgaaatgga gttcataaat ggatcatcca tgatttccac ggaaagaatg
     2761 atgccatatt tagaagcttc ctttacgctt tcttttattc cttcgataaa gtcttctctg
     2821 gaattcattg atttctcttc ataataaaca tcgtatccag ctatttggat tactttgacg
     2881 cttagattat gcgccaaatg gattgctttt ttcattagtt gtttcgctgc ttttttcttt
     2941 tctggatcag cagaaccaaa cggaaatcgc cgatgcgcac ttaaacaaat cgaatggata
     3001 cgtacaccgg agctgaacat ctcttctctc agctcagcta tcttttcttc agaccaatct
     3061 aatcgtgcta accgctcatc cgtctcatca atcgacatct cgataaaatc gaagtccatt
     3121 tcttttacaa gggaaaaacg ttctttccat gaaatatctt tgggtaacgc tttttcataa
     3181 atcccaattt gagccatttc cttaccccca gatacgaatg atctcatctt tgaagttttg
     3241 tgcggccttc atcggatcat ttgctgctgt aataccacga ccagtgataa aggtatacac
     3301 atcgatccct tcaaataagt gtaatgtgtg tggatttaat ccaccagtta cagaaacatt
     3361 aaagcctagt tcaatcagtt ttttgatctt cgataaatct ttttcacccc aagtttcacc
     3421 agataacagc gcatcacggc tttgatggta gattacctgc cggataccga tgttatgcca
     3481 atccatggct tgttcaaaag tccaattgcc gtagagttct acttgcaatt cacctatttc
     3541 tttttgtgct gcctccatag ttggaatcgt tgcacaacaa atgactgtca tccagtctgc
     3601 tcctgctttt gcaacattac tcgccactgt tcctccagcg tctgcacatt tcgtatcagc
     3661 gactagtttt ttatctggga acatactgcg aatacagcga atcgcttttt gtccttcctg
     3721 taagcaaaga attgtgccca cttcaataat atctactaca tcaccaactt tcataacatc
     3781 tcctaatgca tgttctaagt cattgtgatc taacgcaatt tgcaaattcg gcctgctcat
     3841 cttagttcct tcctttactt gtttttttgg taccactttg tttcagcaaa tttttcactg
     3901 atttctttga ctgacatcac atttttgata ccgataactg taactccttt tttctctgcc
     3961 tgagtaaaca tattcaaaaa attgactggc gtaaaaacta catcgtattg gccagctgaa
     4021 ctttttccct ctgaaatggc acaatgatgg attttggtaa ttggtacgtt tagttctttc
     4081 attgcttttt ccacacttct catcatcatc aagcttgttc ctgatccatt tgcacacgat
     4141 actaaaattc tcatcttaat ccctccatta tgagtgttgt ctaatcagat tttcttttat
     4201 actctctgct tttctgcata tgtgtcatag tcttctacaa tcaaaaaata accatcagga
     4261 tttttccgat attgtaactg cggaatagcc aataaaccaa tgacaactac ggcaattcca
     4321 gcataaccta ggactttcat gattactgta aacaatggcc aagctgttgc ccagtcgaac
     4381 atcccgatat aaccaccgta tgttgacatc ccaatccatg tagcgaataa tgctgaaccg
     4441 cctacttgta tgattcctga aagaaacggg aacaggcaag cggctttgaa tccacctcgg
     4501 ttattggcat aaactgctat aacggcatta tcaaagaaca acggaatgaa accggctatg
     4561 acgatcgttg gtgatttcaa taaaatcagt aaaccaatca tcaaaaactg tcccaaagca
     4621 ccaaacaaga acccaatcgt taccgcattt ggcgaaccaa agccaaaagt agcagctacg
     4681 tcaattcctg gaacagctcc tggtaaaatc gtgtttgaga ttccttggaa agattgagtt
     4741 agttcatcga cgaatgtccg aacacctaat tgcaagatcg ccagatatac cgcaaaattt
     4801 aaagaagtcg tcataatgta gaataagaaa ctctgccctt cttgcatgaa ttgcgcttga
     4861 atcaaataat ctttgcctag tacaatcaga atgatcccaa agaaaaatag catgagtaac
     4921 gaagtagcaa ccatattctc attgaaaatc gacaagaatc ctggtaattt gatatcttca
     4981 atttttttgt cttgcttgat tgatctattt ttcttttcat cccgcttttt catccactca
     5041 gctaattttg caaatataaa gattccgaac atttgctgat gtgccactgc aaatccggca
     5101 ccttctgtca attcctgcgt gattcctact gttaagttag aagctactgt ccaataacaa
     5161 cctaaaatca gtcccataaa aatcaatgct tgtatcctac ctagatcagg aaagcaaaac
     5221 agtaaaatcc aaaaagcggt agctgcttgt tgaacctgaa cgtttccggt agtgaaaacg
     5281 gaacgcagtt tcgtatattt ctgaaaacgg actaataaga tatttaaaac aaatgcaatc
     5341 agtaataaaa tcatcacatc tccaaaggta cggccaaatg tctccattaa tccagcatcc
     5401 acagcatttt gtccaaaata aggatctgta accatggcat ccaaattgaa ccgttccttt
     5461 agtccaacca agattggccg aaaattattg accaaaccac cagagccaac agtcaaaata
     5521 aagtaaccga ccgttgcctt taagaatcca gcgatgcatt catgaagcgg gcgtttcagc
     5581 aaaatatagc ctaataacac gataaaacca atcaggtatg ctggctgcgt caagatattt
     5641 gttgcaaaat acgtccaaat gcttaacaaa aattccccca tcttttttct cctctatcaa
     5701 ttaattatat tctgccatca caacttggta atcatcgatg gagttcgtag agatgagacg
     5761 ctcaaccaat ccatctgtca ttaataattc ggataatttt tggatatttt ctagatgttc
     5821 ttctggatct tttgctgcga gtgtaaaaaa caaactagcc gttttctcct cattctcccc
     5881 ttcactttca aaacggattg gctgtttcaa cttggtaaat gaaatagctg ttccaaaaac
     5941 accatcactt ttttctgaag aatgcggcat tgctacttga ggtgcgatca caatataagg
     6001 accgtatttt tctacacaat ggatgatctc ctccacatac gtttcatcaa taatttcctt
     6061 atcgatcaat acaagacagc tttcggcgat agcttcacgc caatccgtga tttctttatc
     6121 tgggtaatga atcaattgat ggtcaaaaaa gtatttcagc aagaaactcc ccttctttct
     6181 tataaaaacg acggaaacgg tgtatcattt tcaatcgaga agacatcttc aaatcctcga
     6241 taaaaattaa actcaagatc atctttgttt gtcggataga tgaatttccc gcctacttgc
     6301 cagatataag gtttaaatcc atacttcagg cgatcctttt tgaatttcca aatttcagtg
     6361 atctcttttg gatcagccat aaaattagac caaatatcgt agtggacagg aatcactact
     6421 tttgcattca atgactccgc catgcgcagc atatcaacag aagtaacttt gtctgttatc
     6481 cctcgtgggt tttcaccata ggcccctaaa cagacatcga ttttgtgttc attaccatgt
     6541 ttggcaaata aattggagta atgtgaatct cctgcatgat aaagattccc tcctgatgtt
     6601 tcgaataaat agtttactgc aatttgatcc atctcctgag gcatttttcc ttttaatacc
     6661 tcttctggat cttcacaagt gaccaacgct gtccgatcaa acgcttctaa agctactaca
     6721 ttgatgtctt tgattttgac tgcatcacct ggctttactg taatcgtttt ttcttcagga
     6781 attccccatt tttgccacgt gcgaaccact tcttttggcc caatgaatgt tgcttcagga
     6841 caattttgat gaactgctgc ggctgtatgg atatctagat gatcggaatg gatatgtgta
     6901 acgattaaag cgtctacatt ttttatcgca aaaggatcga ttacgaaagg ctgagtacgt
     6961 aaattaggct gcatattttg aacgccactc atacgcatca tctgatggcc ttttttcatc
     7021 atgccattcc catgactacg ttttcccgtc ccacaccata gatcacataa aatattcgtt
     7081 ccttcatgac ttttcagcca aattcccgta cagcccagcc accacatagc aaaagttcca
     7141 ggatccacta cttctgtttc gatttcttca ttcaagtatg tgccccactc aggaaatgtt
     7201 tctactaacc acttttcttt tgttacttca ttgacagttt tactcatttg cttgctcccc
     7261 ccatatcgtt gttccaactt acaagtaaat attaatgtgt atcagcatcc atgaaaaccc
     7321 ttttatatga ccgtttgttt tttatatgat tttctttcag taatcaatga ttgtttcagt
     7381 ataataaaga cagatatgaa tgtttaaatg aacaactagt caaataaatc catggatcaa
     7441 gatgtccctc aggaggcaaa agtcatgaaa aactcacttg tcaatattga aaaacgtcaa
     7501 aaagaaattt tggaactgct tcagcagact gaacaactat caactttcga attagctgaa
     7561 tcccttgatg tatctattag tacgatacga agagatttaa atttattaga agaaaaaaac
     7621 gagatcatac gcaattacgg ttattgttct tataattaca aaaaccagac tgattttgat
     7681 caatctggtc ctgaaaggat taaacaagcg attgccagag aagctagtaa atacattaac
     7741 gattatgata cgctgtttat caattctagc tcgactgcgt tgaaaacact ggattttctt
     7801 caatctaacc atttgacagt cattacaaac aacgtgaaaa tcaattactc tccgcacaaa
     7861 gataattgta gttatatttt aactggtgga gagatgcgct ttccaaaaga agcactagtg
     7921 ggcgacatcg cattaaatac gatttcttca gtcaatgcag acatttgtat cattggctgt
     7981 agcggagtcg atgtagtaca tggggtcaca acaaagatat taaatgaatc aacgatcaac
     8041 gaaatgatgg tcaacaagac aatcaaatgt aagattttag tcgctgatca tcgaaaaatc
     8101 ggactgacat caaagttcaa gattgctgat atttcagtct ttgattattt gatcactgat
     8161 aaattttgtt ctgaaaaagt attagaggag atcagaaata cggggataaa aaccattcaa
     8221 gtagattcat tttaagaacc aggacgtaaa tatgtaaata ggattatcaa aaaaatgaat
     8281 aacaaattta tcgataaatg aaaaacacgc tacgctcaaa ttgataaagg aatcccaaga
     8341 tgtatccatc caatcgatac catcataatc tattgcttct tttataaccg ttatatgttg
     8401 cctaaatagg aatcaaacaa tatcgaaaaa aggaggtatg acaaaagtca cacctccttt
     8461 tttcgaataa acggtattca aatcagaaca ctgatttcac aaccacttta tttcaggtcg
     8521 ttttcaatca cctttaccgc gtaatcattt ccgttgaaac gcgctatttt ttttgcgtcc
     8581 atatatcttt ctaaataatc atcttctcct aattgcttat ggcaagaagc aatttcataa
     8641 agcaagtatt ccaatgcata agtcgattta tgtttcttat tatactcaat acccttctca
     8701 cataattgga ttgctttatc ataatcctcg attttacggt aataggtggc gatatcataa
     8761 tatacaatgc agaccatcag attatcaaaa tcagtctcac tcaatatttt aagtgtacgc
     8821 tccacataaa ctttcgcaaa atctaattct ccttttgaca agtagatcat tgccacgttt
     8881 gcagctgctt gtaagtgatg gatatctgtt tcggtcgttt gttccaacac ttgattaaaa
     8941 taaaataatg ctgcatctgg ttttttcgca taaagatgat caagcagtcc ttgataaaat
     9001 aaaatttgat ttaaaagatc agaattactt actttttcct gatcgatcgt ttgtaaaatt
     9061 ttataagatt cttggtattt tgatacagaa ttcaatgatt gaatctcatt tatttttttc
     9121 ctgattttgt cttcttctgt ttctactaat atatcggaga tctcgacatt cagctttttg
     9181 caaagcgcac ttaagatatt gatgcctggc gacatattct tgttttcgat attgctgaca
     9241 gttgcttgtt cacaaatgcc ttctgctaat tgtacttgtg ttaacccctt tttctttcgg
     9301 tattctttta gtaatgctcc atctacttta atcaaaacaa tttccttccc tttaaaaaat
     9361 tatttctcct ttatatcata cacaaaaaaa agttctaaac aaccaaaaat gtttagaaca
     9421 gaataaaaat tttaatttta aaataatatt caaattaaac aactggcgta tctgctcctt
     9481 gatttctttt tgtgttatct gaataattat cgtttacagt tataacacat agtgaaaatt
     9541 gtcatggcga gaaagtctaa gaatattttt aaacataact atttctttct tacgtgtgta
     9601 taatgacgac agcacaccta tcaattaata taattatttt atttttttat gttctcatgt
     9661 ttatttttaa tgacacaact tctcgtattt atctggcaca acatataaat cgatcaaaaa
     9721 attgttgcgt gtttttttga aaattggagt ttcaacttga ttacaaaatt taaatttaga
     9781 agttgtgaaa acagcgagag acagtttaat attcaaaata tacataggct actcgaacgc
     9841 tgtgtttttt agtatactag taagaaacga agggatagac tcattccaat aaggaggatt
     9901 tcatgaagac aattcttttt gctcctgcag tattcaattt agctgagaca acacgaatga
     9961 ttgaggttgc caaagctatg aaagaccgtt attactgtgt attctttggc ttttctaaaa
    10021 cttttgctcc tttgatcaca gaaagtggct ttgagtatca tttactagcg ccgatcctta
    10081 cgaaaaaaca agaagaacaa atcataaaat ttgaccagtt gcgtacactt aaaaaccctt
    10141 ttaccaaaga aatggttgcc tctcgtatca ctagtgaaca gagtctgatt gctaagtttg
    10201 agcctcgact gattgtgaca ggttcgaatg tgacaatttt tttatcggcc cgcaataaaa
    10261 agattccttt agtatatgtt aaaccctatg ctttgagtga accttttttt caatcagagc
    10321 atgcgctgat gccccacgag ttacgtttct tcggcccttt aagcaatccc ctttggcact
    10381 ggacaaaaaa gcgtatagta aatacccgat ggatccccaa tgccttcaaa cacgctgcac
    10441 aaaaagaaat gcttccttta ccaaaaacaa gtttacaaat gatggatgct gatctaaatc
    10501 tcatcacaac gcctaaacta tttttggaag aagaacagct gccggaaaat tatcgaatcg
    10561 ttggtccaat ttttgctaag ctcagtactt ccttgcctga agaagtgcta acttttatac
    10621 agcgaaagca acaagaaaga aaacgtatta tctatttcgc aatgggtagt tcaggcaatc
    10681 cgcgtatgtt acgcaaaatt ttgttcttct tacaaaaaca accggatcta gcggttattg
    10741 cacctattga ctatctgctt gatgacattc aatctgactc agaagatctt ttaataacag
    10801 aatatctgtc tagtcatctt ttgcatgaat tcattgattt ttcttttatc cacggcgggg
    10861 aagggaccgt ccaaactgcc tgtgaatccg gcaaaccgtt tatcggtgtg gggatgcaat
    10921 ttgagcaaag ctgtaatatt gactattgtg taaaatacgg aaacgcaatc gccctcacaa
    10981 aaccagtgac tgaaagaaaa ctgcagattg ctctgcgcga agtttcttca cccaagattc
    11041 gtcagcaggc acgcacgctg caagccgttt ttccaataaa tggtccacaa caagcaattc
    11101 aagaaatcga aaccttcctg agcaaccacc caatatagtt tcaagtagaa aaagcttttt
    11161 taatagagac tcatcagtaa tttcgctatt cgagacccag acagtgaaaa tacaaaaaaa
    11221 gtaaatagtg gattgaaaag ttagagttac ttaaattacg gtgtctaaaa aacacaaaat
    11281 catccttaaa ataaaagatc tgacgctatc caaatgagca taggtagcgt ctgccattta
    11341 ttcttagtca aattctttga cacctttctc tggttggatc atctcaacgt ttcttcaaaa
    11401 gaaagaccat aataattagg caaatacatt ttcttaaaat gtgtcatata gatctagaag
    11461 catcgctttg tagagatttg tgccgctagt cccctcaaca attactaaat caaatgtagg
    11521 atttaccact ttatctttga taatcaacct ccctcttctg ttgagacaat gatctcgcaa
    11581 tccgatgcat actcctatat aaactgccag caatccccac atattgagta gatcatgtca
    11641 gaatgttcta tgtcgtcagc aacgatacac taaaagtcac gttcaccatg actgattgct
    11701 attcccagca caattatttc tatacacgtt tcatgatttg aataaacact cacatcatac
    11761 atattaccat tcatacacca tactgcagcc cctactatat ggttgtaagc tcccaaatct
    11821 atatttgact tgatcacttt ggtagtagat ctactaattc taaatccatt gctgataaaa
    11881 tttccatttt ttcctccttc tttctgccaa aacagttaaa acaataataa tctttatgta
    11941 aaaaagggct gtgacaaaag ccttgtcaca gtcccatatt ccgaataaac ggtggtcaaa
    12001 agcttgcatc tgcggtaata agttcaacca aacgaaaaat aagccaacat ttcacaaaaa
    12061 tttaagaagc aattttcgta aatttcttct tatttcttga agctaaccac ttctgttaca
    12121 accactttta gaacatttaa agcttcgatg tgacaaacca tctatgctgc tcgatcataa
    12181 aattgatagc aaaaattcca caaagtacat atgtccccca tgaaaacaaa acattcatat
    12241 gcggtacaat gatctttgga agaatcacga tcaaaaatga tgccagtgcc caaatccatc
    12301 gattgatttg aatatgatat gtagctagca tattcaatat aaggtgacta gccgttaata
    12361 aaaagataaa aacaaaaaat aaaatcagcc aatacattgt ttcccacctt ctaaaaacca
    12421 aacttagaca gtctggactt cgttttctcc acgactttgt tcatctgaca gcatcttttt
    12481 atcataagct tttacaaatg gataatagat aataaatgct atcaatgtgt tgatcatgat
    12541 caagataaca acacgccagt catttcctgc tgaaagataa ccgccgattg gagctggtaa
    12601 tgtccatgtt ggcaaaacag taaatctatt gaccatttct aatttgactg caaaataact
    12661 gataatagtc aaaactaaag gaactaagtt gaacgggatg aacatgtaag gattcaacat
    12721 cataggagct ccaaaaatta tgggctcatt gatattgaag ataccaggaa taatagaaaa
    12781 acgaccaacc tctttcaaga attttgattt acagaagaat ataaacaaaa cagataccac
    12841 gatcgttgct cctgcaccac caattgttac cgtccattga taaaactgtt caggagcgat
    12901 atagggtaat tgggtggcag ctgtaccatc tgccaatgcc tttgcattct catccaacat
    12961 gatcagccac attggacgaa caacagcccc tacaatactc atgccatgga taccaaatga
    13021 ccacaacaaa tggatcaaaa acattggtag taaaacacca agcaaattat tccctaaaat
    13081 attggttaaa ggctcgaata acgataataa ggcagcgttt acatcaaagc ccgcgacgct
    13141 tcgaatcagc caagtaattg ttaaaatgac tgcacctgga atcaatgcct caaaactacg
    13201 ggcaacagca ggtggcactt gttctggcat tttgatagta atatttcgat ttttaaagaa
    13261 acgatatact tccactgcaa aaatcataga taagatcccc gcaaacatcc cagatgctcc
    13321 caaagaactc ataggtaaga cccagccaag aggtgcctct tcaggagtta aaacgtttac
    13381 aggaacttgt aacataaaga acgttcctaa agataatata ccacctgtca cactatctaa
    13441 tccatatgat ttagctagat ccgaacccat aacaaaagtt gcataaatag ccatcaatcc
    13501 catcgtcatc ctaaagggta aaacaatcgt tgccgaataa ggggcaataa attcattcca
    13561 tccaggaaac ggtaaattga taaagaccat aaaaaatgtc ccaatcaaaa tcaatgacaa
    13621 tgttgaaaca accccattac gaattgctaa taaatgacgc tgtgtaccaa tttttgccat
    13681 tggtgggaca agtttctctt cgacccattt catcagcttt tccactaaaa ccactccttt
    13741 tcaataaaat atgaaccatt cattgcatga caacgcaaag aatgttcata actaattata
    13801 taattaagaa attttatttc aatatattct cttaaataat caaatttatt tttaagaatc
    13861 ctgaaaataa gttttctaaa tcataggagc aacaaaaaaa ttcgataatt aacaaaaatc
    13921 aaaatgatta aatctagtga ttgaaacata tcatttcaaa aaaattttgt aaattcaccc
    13981 ataaatatca ccctatttaa cttttttcat cgtacactaa aattcaaaac aactatcttt
    14041 aatctttact tcttggtttt gttttaataa atttccttca aaaatgcctg gagaaactac
    14101 aatgatcacc gtatcttttt gtgcttgctc caacttcttc aaatctataa tagctaacag
    14161 tgtcccttct tttacctcct ggttactttc aacccgtatc tgaaacggac ttccttcgag
    14221 ttcaactgta tctaaaccca tatggatcag tatttttctg ccagattcac tttcgatcgt
    14281 tatggcatgt cgggtaggaa atatattatc gattattcct ttaactggcg catggatata
    14341 tccatcatga ttcgttatag cgtatccaac tcctatcatt tttgaagaaa agacctcgtc
    14401 ttttactgct gttaatggaa taatttgacc actagctaca gcttttagaa tgtttcttgt
    14461 tttaaagaaa tgcacttttt atcacctcta ctttaatgct ggccaatatt ttttgtttac
    14521 tttgatcatt tcatctagta ttttttttgc gactctggca tttggtacgg tttgattcaa
    14581 tgtaaatgct tgtaaagctt tttgataaga accttcaaag taagcatcta ctagtaactt
    14641 ctctactgca acttgtgcct ccatcaatcc tttatgaaaa tcactgattg gttttcttag
    14701 tgtaattggc tccacaccag ttgcaccaac atatgccggt atttcaacaa ctgcatctga
    14761 ccgtagattc ggaatcgccc cttgattagg aacgattagc ataaagcgac gacgatcatc
    14821 attcaacaag gaaatagcta tatcgacgat atattgtcca tgctccccaa aattaaagtt
    14881 caatacttct tccacaatac cgcggcgtat tttatcagcc atttctttgg tatttttctc
    14941 tcgtccatcc atgaccatat tagcacgtgt atactctttg tcagtatgct caacgaccat
    15001 atcaggatat aagtaatact ctaagtaatt attcgggata ttacttggaa aatttttcgt
    15061 gatgactgac atcatttgaa aggttttttg ccaagtttta tctcctatat taaaatcggc
    15121 gacttgcatt tcttttgtta ttagtttttc aataatctct ggcataattt ctcgttgcaa
    15181 ttctttatca taaatcgatg tataccagcc aaagtggttt aaaccataat acgtaacgat
    15241 ccaattctta cgatcataac cgtaattcac tgcaatcgtt tcttcaattg aaatagtcat
    15301 atcacaggca ttaatcattt ttacattcgg atatttacga cgaacagctt cagaaacgat
    15361 cgactctgga tttgtataat tcaaaatcca tgctttgggg gcatagtctt gtatatgatc
    15421 gacaatttcc aataaacctt tgattgagcg catcccataa gcaaatcctc cgagtccaca
    15481 cgtttcttgt cctactaatc catgtttaag tggaatcttt tcgtcctttt ctcgcatctc
    15541 caatcctcca acacgaattt gtgagaaaac aaaatcgcat cctgtaaaag caagctttgg
    15601 atcatccgtt gcacgaatgc gaatatttga aaaacctttt cttttcagca taaatttaac
    15661 aatcaagtac atatccatat ttctttcttc atcaatatca tataaacgta tttcagataa
    15721 tggcaaccgt ttttcattgt tcaaaatggc ttgaacgatt cctggtgtat acgtactccc
    15781 gcctccagct atagtgataa tctgtttttt catcatcatc ttttcctttc tattcttcta
    15841 ataatttatt gaattctgcc ataacataag tcacttctaa gccgatgata atttgataat
    15901 ttttttcagt tggtttaatg atcccgctta tccctaattg cttgattcgc tgttcctcga
    15961 ccatggtggg atccactacc tctacccgta ggcgtgtatt acaactatag acatccagga
    16021 tattggcttt tcctccaaac gcttgtagca tttttgttgc catatattca taatttttac
    16081 ttgctaaccc taactctgtt tcttctaagg ttacttcatt gccaaactct gccttagctt
    16141 cacgtcctaa tgtctgaatg tttctcttat tgatcaaata ataaaaagta acgtaataca
    16201 aggcaaaaaa gaaaattccg attggaagaa tcaaaatagc attggtagcg attcgaaaat
    16261 tgatgagata atcaacaata catgctccga atgtaaaacc aattcgtata ttgaataagt
    16321 aacagacaat ccctgctaaa ccggcaaaaa gtgcatggat cacgtacaac ataggagaaa
    16381 gaaacatgaa actaaattca acaggctcag tgatatttgc aataaatgaa gttcctgcac
    16441 cgcttcccat gattcctttg accatctctt tattttcttt ataagctgct ttatagatag
    16501 ctagacatat agctggtata ccaaacatca ttactacaaa aaaaactgat aaaaacagtc
    16561 cagcctgagg atctccgttg ataaagcgtg tcatctctcc tctgaaaact tccttgctag
    16621 gagatgtata gcttcctaaa tcgtaataaa tatacgtatt caacacatgg tgcagtccaa
    16681 aggggatcag caaacgattc aaaaacataa atatccccac acctaatgct cccatatcaa
    16741 cgagcagttt tgcaaaatta tcaatcccaa tttggatgag cggccagata aagcccaaaa
    16801 aaacagctgc gattgtttgt agaatcatca ccatagtcaa tgggaatttt tcgcccgcaa
    16861 aataagaaaa aactactggt aatttttgtt ctttaaagcg attatacgtc catgccgcta
    16921 ctaaaccgga aataattcca ccaaaaatcc ccatattcac ttctgggtcc ataatttcta
    16981 agcctttttt caaggtagca atcgctaaaa aaccagtaag tgcaggtatt cctttgtcct
    17041 tatttttgac aaaaccgatt gcaactccta tagcaaataa gatatccaag tttccaaaaa
    17101 cggcatttcc agctgcacca attactggga tgttcagcat atcgtcagct gataaacgca
    17161 tgatcaatcc cgctaatggc atcgctgcaa ctggaagtag catcgctctt ccaagcttct
    17221 gcacatttga tttaacattc atttttattc ctcctctatt aaatatcctc atatgttact
    17281 aactcaatca aaggatcatt tttcactttt tgagcaaatg ctgaatgaat taaaaattcg
    17341 acttggtggg tacgaggata cacaaaactt gaaccattta acaattcctg atccaaatac
    17401 gctgcgtgac acatgacttc gatcgtttta tcttctctca atatcatgag taaacttgcc
    17461 aaatattctt ccacactcgt attgatttgt cgtttttttt catcagtttc tcctacgaca
    17521 tcgaaacaag gctcaaaata atcgacatga cgaacttcat cttttcgttc aaagttgctc
    17581 cgaaccggca aatcatattt ttttgctaat gtaacaacta cctcctgatt ttcatccaaa
    17641 gtatgagtat gatgatgact gtctaaatga gttggtatga tccccgcatg ataaattttt
    17701 tgaatctgag cattccattc ctgatacagt tgatctttgt caatgttaaa tggatgctga
    17761 taataagata aggatctgaa ctctccgctt tcgataagag tatcgacagt tttgaggagt
    17821 ggtttgccac acgtcaatgt taaatggact cctacaccta gcctaggcat ttcctttctt
    17881 agtttcacag catgctcgaa acccggcata tttgccatca atgtagttga tgtcaaaatt
    17941 cctcgctgat aagcatccat aatcccataa ttcacaccat ggctatagcc aaaatcatcc
    18001 gaattaaaaa tcacttttcc catttcattc tccttctttt ttctactaaa ataggcgcaa
    18061 ccaaataatc atagtccatt tactatgtgt catttggttg cgcctataga tagttacgcc
    18121 cttattttaa tagattcttg ctagatgaat tgccaaatag atgatttcat tttcttgaat
    18181 ggcaagttga aattgctgtt cgatgatatc tttaatcttt agtgctgtac aatacgcttt
    18241 gctatgttta aatgtttcag taaaaaaacc aatattttct actggcgttt cttcctgata
    18301 aatcaagcgt ttaaccagga atttgatatg aaccattaag cgatgataag tcagtgattc
    18361 tttatcataa acgtttgaat aggatttttc tagatgggac aaaatcgtgg tcgtcatttc
    18421 tactattttt aagctcttta aactattagg ctctcctagc tcagcattaa tgatatgcat
    18481 agtgatgaat cctacttcat ttgaccctaa ctcggtttga tatcgatgat tgattcgctc
    18541 gaccacttct actgctatat catattcatt tggataaagg aatctcattt ctggcaacat
    18601 aattgctgtg acatctctat cttctctttt tcgttgaata gcaaaataaa tatgatctgt
    18661 caatgtaata tagatatttg aatctaatgg agaggagatc ctagctgtta tcagttcaat
    18721 cacttcttcc gcaaaatcca taaattcgat tggaatctgc gagactatct cactgaatcg
    18781 tttgatcttt tctttagaat ctaatacaaa taatttgtca gcatcctcaa catcaaatgg
    18841 cttactcact ttagcagaaa agccaatccc tttccccatc gcaatttttt ctattccatc
    18901 gtcatcgatc aatacagcat tatgattcag ctttttcatc acatacaccg ttaattcacc
    18961 tcctctatat gataaaacaa aacaacttgc agactccttc atacatattt ttgtctccaa
    19021 acaattttta aagacaaaaa acgacctaag aaagaaccct ttcttaggtc gtgcctaatt
    19081 gaatagtagc accctacata atttacaaaa atagtttaac acataataaa agcgttatca
    19141 atatcttttt tactcgtttt atgataatac ttgtatcgaa ttgatttgga ggtaattaca
    19201 taaaaacaaa aaaaatatag caactctcta taagaaagtt gctatattga taattatacc
    19261 ggcggccggg gtcgaaccgg cacgtcctca acggacactg gattttgagt ccagcgcgtc
    19321 tgccaattcc gccacgccgg caaatttaaa aataataact ggggtagctg gattcgaacc
    19381 aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca agaataaagg
    19441 gcgaatgatg ggaatcgaac ccacgaatgc cggagccaca atccggtgcg ttaaccactt
    19501 cgccacattc gccatcataa aagatgttat ttaatttctc aataaaaaac taagatgaag
    19561 acatcttagt caataccggc ggccggggtc gaaccggcac gccctcaacg ggcactggat
    19621 tttgagtcca gcgcgtctgc caattccgcc acgccggcaa gttgatttat tagtactaag
    19681 gcggtaaccg gatttgaacc ggtgatgaag gttttgcaga cctctgcctt accacttggc
    19741 tataccgcca ttatactatt atcaatctat aaaataaaga ataaattata gaaactgggg
    19801 tagctggatt cgaaccaacg catgagggag tcaaagtccc ttgccttacc gcttggctat
    19861 accccaagaa taaaaagggc gaatgatggg aatcgaaccc acgaatgccg gagccacaat
    19921 ccggtgcgtt aaccacttcg ccacattcgc catggcaggg gcagcaggaa ttgaacccac
    19981 actaacggtt ttggagaccg ctgttctacc tttaaactat gcccctataa aatggaggag
    20041 agtggattcg aaccactgaa ccctaaggaa cggatttaca gtccgtcgcg tttagccact
    20101 tcgctactcc tccatggtgg cgcgggacag aatcgaactg ccgacacacg gagcttcaat
    20161 ccgttgctct accaactgag ctaccgcgcc atattttaaa attattaatt gaataacaag
    20221 aacgacggtt ccgacgggaa tcgaacccgc gatctcctgc gtgacaggca ggcatgttaa
    20281 cccctacacc acggaaccag ttcattatgg aggttaacgg gatcgaaccg ctgaccctct
    20341 gcttgtaagg cagatgctct cccagctgag ctaaacctcc aacattcaat taaaatgacc
    20401 cgtacgggat tcgaacccgt gttaccgccg tgaaagggcg gtgtcttaac cgcttgacca
    20461 acgggccagg taaatttgct acggagagta agggattcga acccttgaga cagtttggca
    20521 ccatctacat gatttccaat catgctcctt cggcctctcg gacaactctc cagagtgaaa
    20581 gaagctcaat actctttctc aaaatgag
//
LOCUS       DBBGSP010000052        19633 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000052 DBBGSP010000000
VERSION     DBBGSP010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.052"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="ACIZE9_002243"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="ACIZE9_002243"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGC6094073.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="ACIZE9_002244"
     CDS             complement(1172..1867)
                     /locus_tag="ACIZE9_002244"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGC6094074.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="ACIZE9_002245"
     CDS             complement(1880..2596)
                     /locus_tag="ACIZE9_002245"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HGC6094075.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3534
                     /locus_tag="ACIZE9_002246"
     CDS             2926..3534
                     /locus_tag="ACIZE9_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HGC6094076.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3859..4182
                     /locus_tag="ACIZE9_002247"
     CDS             3859..4182
                     /locus_tag="ACIZE9_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGC6094077.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4364..5734
                     /locus_tag="ACIZE9_002248"
     CDS             4364..5734
                     /locus_tag="ACIZE9_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGC6094078.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5864..7165)
                     /locus_tag="ACIZE9_002249"
     CDS             complement(5864..7165)
                     /locus_tag="ACIZE9_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGC6094079.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7519..9510)
                     /locus_tag="ACIZE9_002250"
     CDS             complement(7519..9510)
                     /locus_tag="ACIZE9_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HGC6094080.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9654..9920)
                     /locus_tag="ACIZE9_002251"
     CDS             complement(9654..9920)
                     /locus_tag="ACIZE9_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGC6094081.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="ACIZE9_002252"
     CDS             complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="ACIZE9_002252"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGC6094082.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="ACIZE9_002253"
     CDS             complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="ACIZE9_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGC6094083.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13264..13827
                     /gene="def"
                     /locus_tag="ACIZE9_002254"
     CDS             13264..13827
                     /gene="def"
                     /locus_tag="ACIZE9_002254"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGC6094084.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14080..14601)
                     /locus_tag="ACIZE9_002255"
     CDS             complement(14080..14601)
                     /locus_tag="ACIZE9_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGC6094085.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14604..15446)
                     /locus_tag="ACIZE9_002256"
     CDS             complement(14604..15446)
                     /locus_tag="ACIZE9_002256"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGC6094086.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15439..16164)
                     /locus_tag="ACIZE9_002257"
     CDS             complement(15439..16164)
                     /locus_tag="ACIZE9_002257"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HGC6094087.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16340..16636
                     /locus_tag="ACIZE9_002258"
     CDS             16340..16636
                     /locus_tag="ACIZE9_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094088.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     regulatory      16892..17066
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            17204..18796
                     /locus_tag="ACIZE9_002259"
     CDS             17204..18796
                     /locus_tag="ACIZE9_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGC6094089.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18809..19549
                     /locus_tag="ACIZE9_002260"
     CDS             18809..19549
                     /locus_tag="ACIZE9_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGC6094090.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5620 a         4028 c         3724 g         6261 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcaaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 gaaagcacag gtgaaggtgg cgaaccagaa gtgatcggtt caacagaaga ataatactga
     3541 aacaatcagg tggtgttaga agcggcgggt cagcagcttt taacacgcct tttttatttc
     3601 taatcgttta ttttcatatg gggcttccac ttttgtaaat ggctttacaa acgaaaaatc
     3661 ctaatttacc aagcttttcc tcgcatactt ttatcgtacc tttataaaaa tttatacttt
     3721 gaaaaaaagt attcaattat tgttgcattt ttcctgattc tttattagaa tgaaccctcg
     3781 ttgaagtaag tatttctagt ttatcctagg attaattata aaaataaaac attcgttgat
     3841 tcgaaggagg ttaaacagat gtttgaaagt tttgatagca gccgcaaccg ttacgcttca
     3901 gttggtgtcg tatcaagttt gccagatgaa ttgattgaca gtatatggtt tattattgac
     3961 ctagatctta agggagtcat tccattagaa aatatattaa cctttgattt gatcgaaaat
     4021 cgtggaaaag tgacgatgca tttttctcaa gcaggaagca atgtggaaat ggatattgat
     4081 ttgccgtttg cctattcgaa ccaatttcct gctcaagtat acgcctatga tgacggtacg
     4141 agagaaacga tccttttacc aagtgagatt agacaatatt aaggtgatag ataaacgtgg
     4201 atgtccctta ttttacagac caggccaagt tgttgattct ttgactcaat tcttggcttc
     4261 tttttatgga gtttcataaa ttatcattga tttctaattg gtattctcag gataaacgct
     4321 atatactact aactaaattt taaagatata aggagtttaa aagatgcgcg atttaacaaa
     4381 aggaagcccc gctaaactga ttttgatgtt cactgttcct ttactgatcg gaaatgtttt
     4441 tcagcagttc tacaatatga tcgatatgat catcgtgggt cagacgctag gtaaaaatgc
     4501 gctggcagcg gttggtgcaa ctggaagcct gacatttttg atcattggct ttgcccaagg
     4561 tttaacagct ggtttagcca ttattaccgc acaacgttac ggtgcaaaag attatcgggg
     4621 tctgaagaaa agttttgctg ctagtgttgt cattagtctt gtcgtcactg tgattttaac
     4681 tgtcctaagt ctcctgttta ttcgtccgat gcttcaattg atgcaaactc ctcctgaaat
     4741 acttgatcaa gcacaaacat ttatttcaat tattttatta gggatctttg catcagtcag
     4801 tttcaatttg ctttctaatg tcattcgcgc acttggtgac agccgcacac cactattctt
     4861 tctgatcatt gcggtcatca tcaacgtcgt acttgatttg atctttatta tctattttgg
     4921 catgggtgtg gaaggtgcag ctattgctac agtaatcgca caagtttctt ccagcgtact
     4981 gtgtctagtg tatatcaaga aaaaaatgcc tttgttacag ttacgcaaaa aagatttcaa
     5041 atttgaaaaa gaagagtttg ctgtacacct aaatgctgct ttgccaatgg cgtttcaatc
     5101 ttcgatcatc gctgttggtg ctatcgtgtt acaagcagca ctaaatagtc tagggacaga
     5161 tgtcgtagct gctcaagccg ctgctggtcg tatcgaccaa tttgcaaatc agccgatgat
     5221 gtcatttggt attgcaatgg caactttcac tgcacaaaac tatggtgcga aagaatatgg
     5281 ccgaatcttg caaggggtac gtcaaacttt actgatgagt gtcggattta gtctcttagc
     5341 aggtgctatc gtcattttct tcggtcattt ctttgttcaa ttgtttgtta gcccatcaga
     5401 aacacgtgta tttgaattag cacaaaccta cttcaatatc aatgggtctc tttactggat
     5461 cttagcagtc ctgttcattt tacgctacac acttcaaggg cttggacaaa gcaagatccc
     5521 tacgatcgcc ggtatgatgg aattgcttat gcgttctttt gcagctatcg ttcttacagg
     5581 aatgtgggga tacccaggag cagcagcagc ttctccttta gcttggatcg gttctgttgc
     5641 cgtgttgctt tactcttata tgcgttcgat gaaacaattg aaacacatgg gtgaagagga
     5701 acatttcaca ttagaacatg cagaagcaag atagccttga ttaaaagaaa tcgttgcggc
     5761 taaaaatgaa aacttttatt gaaaatatct tcttcgttta ccgaaaacag gttttttaga
     5821 taacaaaaag gctgtgacaa aaaatgtcac agcctttttt cttttattct gtttttcttt
     5881 ccgtggactc tactttgaaa taatcgatat gtgcatgctg gtattctaat accgtgaaac
     5941 ggaatgatgc aatctcaatg attgttcctg cttttatttc tttatatcgg ctagaagcaa
     6001 agcccgcaag tgtagtaaaa ttcgtttctt caaactctgg aatctctaca tgaaaataac
     6061 gctggaaatc atctaatgtt agtttgccgg agatgatata agagccatct gactgttccg
     6121 ctatcaatgc ttcgtccaaa tctgtctcat ctcggatttc cccgacgatt tcttctaaaa
     6181 tatcttcaat cgtcactaag ccgcttgtcc ctccgtattc atcttttaag atagcaatat
     6241 gcttaccctt ttttcgcatg atcgtcaata atttttttat agggatcgtt tcagttgtta
     6301 cgatcggctc ttcaatcaac tgttctactg tcagctggtc atctttataa gattgcttga
     6361 tcaaatctgg caaggtgaca taacctaaaa cattgtcttt tgattctaag ataaccggat
     6421 agcgagtatg tccttgttca atcgaagctt ttatcgcttc tttgacggtt tctgaagctt
     6481 cgaatacttg catggacgta cggtctactt gtatatcttt tgccaaggta tcatcaaatt
     6541 caaacacgtt ttccaaataa taatattctt ctttggtcaa ctctcctttt tcataagaat
     6601 tcaatgcgac taatgtcagc tcttcttgag acaatgtctc ttctccttca gatacgagac
     6661 gcacacctaa tagcttccct agccctgcag ctgaatgatt caatacccaa ataaaaggaa
     6721 acattacttt ataaaaataa tgaagtggtt taactacgaa caagacgacc ttctccgtat
     6781 tgacgatact atagctctta ggaagcagtt cgccaataac cacatcgata tacgtaacta
     6841 aaataaatcc cagcgccaca gagattgtac tgctaatagc cgaactaaaa ggtagtttac
     6901 cgatcactgg ttctagtaaa gccgcgacag atccttcacc gacccacccg atgatcaaac
     6961 cggttagcgt aattcctaat tgactagctg ataaatagtt atctaaatgg tgtgtaacat
     7021 gaagagctag cttggcgttc tttacatttt ccttttctag ttgttccaat cttgatcgtc
     7081 tgattttcac taaagcaaat tcacttgcta caaaaaatga agtaattgca atcatcaaaa
     7141 ataaaataat gaaattgata accatattct cccgcctttc tctttttcta ttgtaccctt
     7201 tttctacaaa aagattgaaa ataatgcgta ttcatattta ggaataaaaa aggagatgcg
     7261 gcatttttca gccacatctc cttatcactt caaaatcatt gcgttacttg ttgctaaaca
     7321 gctttttcat gacctctgat aaaaacggta ttcaaaagct tgcatctacg gcattaagcc
     7381 caaacagatg aaaaacatga gaagctgttt ttatctgctc gttcttactg cttgttgcag
     7441 tacagctttt tcatgacctc tgataaacgg tgttcaagta gctgacattc gacattagtt
     7501 caggtcaaag cgctactttc acaaccgctc tttcaaccat gttttccgag tatttccaat
     7561 gataagcgga acagtttcat gttttacttc gctgtactct agcccaaacc atgtttctgg
     7621 cgaggtagcg atttttttga ttgccagttt tgcctgcatg atttgacgtt gccattttcc
     7681 tagagttgtc acattggaaa ctacttcatc aatcaggaca aattggaaat cgccaacttc
     7741 tcgccctggt gtcagagagt atctttgtgg ctgttttggc aaacggcctt gtttcatcaa
     7801 atcatggatg acttggcgaa catatacgtt gatttcctgt tggaccctga aacctaagaa
     7861 cagattcact tggacaataa aatcagtgtc catcatatct acttgatatt ctttcgtata
     7921 tggctcatcc gtcacttcca catgaacaaa ccaatagact cgtgctcttt taggccgttt
     7981 atctaaaatc gaatagatga actgtcggcc aactttatct tcagccatat caggaaccaa
     8041 gaagaccaca tttgtctgat agattggtaa agaagtatca tcacgtaatt ctctaagctg
     8101 cgggatataa tctctcaaag acacatcctc ggttgacgat tcgcgaataa tgttcccttg
     8161 ttcccaaata aacatcacga ctaagatgat caaaccaatc agaacggcta caaaaccgcc
     8221 tcggaagaat ttgacaacac ttgagataaa gaaaacgact tctatcgcac cgaagaaaaa
     8281 ggtaactaaa tatgcaagcc aacgagaatg cccattttgg ataagataaa agtaaagcag
     8341 tgctgttgtc atcaacatcg tcacagtgat cgatagaccg taagcagctt ccatatgatg
     8401 agacgttcgg aatgtgacaa ccactagaga acaggcgatc cataaaatca gattgactgc
     8461 tgggatatac atttgcccga tactgttccc aggatacatg atctttaacc gaggcagcag
     8521 tttcaacttg attgcttctg aaactagcgt aaacgaacct gtaatcaatg cttgcgaagc
     8581 aatgactgca gcgactgttg caaaagcaac gccgatcacg atccaacttt gaggcatcat
     8641 ttggaagaat ggattcaggt tcttgatttg ctgtgcttca gggttttgat aaacattcaa
     8701 caaccacgca gcctgcccaa aataattgat aaccaaacaa attttgacgt aaggccagct
     8761 cagacgaata tttcgtttgc cgacatgtcc aagatcggaa taaagcgcct ctgcacctgt
     8821 cgtagccagg aaaatatttc caagaatgaa caagcctaat ttgttatctg cactaaaaag
     8881 cagctggata gcataataag gattcagtgc acggataact gtccagtctt gactgaagtt
     8941 cattaatccc attacgccta aaaaagtaaa ccaagcgaac atgattggtc cgaatgcttt
     9001 tccgacaata tctgtaccaa agcgttggac catgaataaa acaaaaataa taactaaagt
     9061 gataatgacg atcacgttct ggttattacc gaaccggtca aaaaactgcg gaattcctcg
     9121 caagccttca atcgcagtcg ttaccgtcac agcaggggtc aataccccat ctgctagtaa
     9181 ggcagctcct ccgatcattg caggaatgat caaatatttc ccaccttttc ggacaagtgt
     9241 gtagagtgag aaaattccac cttcaccatg gttatctgca ttcaatgcaa tcacgacata
     9301 tttgattgtt gtcagtagag tcaatgtcca aaaaatcaat gagactgatc cgataacaaa
     9361 atcaggattg attcctgaca atccgccatt atcttcaaca atcgatttca taacgtaaag
     9421 cggacttgtc ccgatgtctc cgtagacgac tcccatcgct acaagcaggc cagccattga
     9481 tatctttttg gtattgtgcg ttgttgccac gtttttccct catttcttgt tatatggata
     9541 tcctttaggt aagcttgaat gatagatgat attcttatcc atgacacccg ctttcctaaa
     9601 ttgcttctaa ttatccaagt aacacactga agtgtcaact tatttgaata aaattattct
     9661 ttctttggac gttctctgat acgtcttgcc acaaatgaat aaagagcaag gcaaaaaatt
     9721 gcacccaata atgctggtat caaataaaaa ccgccgagtt ccggtcccag tggtcctagt
     9781 aaaaattcgc cgagccaact acctaaaaaa ccgataatga tatttccaga tacgcctccc
     9841 gggacttcct ttcctaaaat tgcgccagct atcaaaccta atataccgcc gataaataac
     9901 gaccataaaa aattcagcat ctcctttccc tcctttatcc atatttctca cttttatttt
     9961 acgctttatt cagaaggact ccaaaaatat gcgccaagaa actccagaaa aaaagaagtt
    10021 gtaacaaaag tgttcagctt atttccgtag aagctgcttc tggaacaccg tgaatcagag
    10081 gttgtgaaat cagcggtttg acctgagtat tagagaaaca aacggaaaaa tagttcctca
    10141 tattttgccg ttttttgagc taatatcgag ggacagctga ttgaacatcg tttattggag
    10201 aggttgtaaa aaagctgttc tgcatcaagt aataagaaca gccaagtaaa aacagctcct
    10261 aatgttttta acttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    10321 cgaaaaaaaa ggactgtgac acggcttttg tcacagtccc cttttttcga ataattattg
    10381 tccccctgtc accttcacga tcacaagtac attattccta tgaattaaat tatttttctt
    10441 catttttcgt tgaaccatct tcgttcaaca ttgcttttct tgacagattt acgcgtcctt
    10501 gtttatcgat ttcagttact ttcacaagga tctcatcacc tagtttaaca acatcttcga
    10561 ctttattgac acgatcgttt gctaattggg aaatatggac aagtccatct tttcctttga
    10621 tcaagttgac gaatgcaccg aatttttcga tacggacaac tttccctaga taaacttcac
    10681 caactttgac ttctttggtc aaatcttcga tgatcttgat agcttttttg atcatttctg
    10741 catcagctga agcaatactt acttttccat cttgatcgat atcgattttc acaccagttt
    10801 catcgatgat tccgttgatc gtatcgccgc ctttaccgat aacatctttg attttagcag
    10861 gttcgatctg gatcatttcg atttttggtg catattggct taattcttca cgtggagcag
    10921 caatcgttga agtcaattct tctaagattt ccatacgtgc ttgttttgct tgagttaatg
    10981 cttcagttag gatttgttct gtgattcctt gaatcttgat atccatctgt aaagcagtga
    11041 taccatcttt tgtaccggca actttaaagt ccatatcgcc aagatgatct tccagccctt
    11101 ggatatcagt taggatcgta tagttttcac catcagaaac aagtcccatc gcaataccgg
    11161 cgactggcgc tttgattggt acacctgcat ccatcaatgc taatgtgcca gcacagatac
    11221 ttgcttggga agaagaacca tttgattcca atacttctgc tactaaacgg atcgtataag
    11281 gaaattcttc ttctgaaggg attacttgtg ctaacgcacg ttcacctaat gcgccatgtc
    11341 cgatttcccg acgccctgga gagcctgcac gtcctgtaga accaacagaa aattgaggga
    11401 aattgtagtg gtggatgaat cgtttgctga cttccacccc taaaccatca atgatttggt
    11461 gctctcctag aggtgcgagt gtacaagctg ataaagcttg tgtttgtcct cgtgtgaaca
    11521 aacctgatcc atgtacacgt ggcaataagc tgacctctga tgacaatgga cggatttcat
    11581 ccaatttacg cccgtcagga cggatcttat cgatggtgat caattcacgt acgacatctt
    11641 tttcaagatc ttctgtgatt tgtttaactt ctttcaacaa gtgatcttca tcttcatgac
    11701 ctgcaaattt ctcagcataa gcttcgcgga tatcgatctt cacctgctcg atattatctt
    11761 cgcgagcaag tttttcttca gtcattactg ctgctttcat tgtagcgtaa gaagcatcaa
    11821 agatttcttt tttcaatact tcatcaactt gcagtaaagt cacttccatt ttttctttcc
    11881 ctactgcttg aacgatttct tcttggaaag caactaactc tttgatagcg tcaaaaccaa
    11941 acagcaatgc accaagcatg tcttcttctg aaacttcttt cgcgccgctt tcaaccatat
    12001 tgatggcttg tttcgttccg gcaacagtca attcgatatc tgtttgttct gcttgttcta
    12061 ctgttggatt caagacgtac tcgccattta cacgaccaac ttctacgcct gcgattgggc
    12121 cgtcaaatgg gatatctgag attgatagtg ctaaagaaga acctagcatt gctgccatag
    12181 ctggcgagca gtctgtttct acactcatca cgatgttcgt tacttggact tcattacgga
    12241 agccttctgc aaacatcggg cgaattggac ggtcgatcaa acgggcagtc aatgttgctt
    12301 ccgtacttgg acggccttct cgtttgatga aacctccagg gattttccct gctgcataca
    12361 ttttttcttc ataattgatc gttaatggga aaaagtctgt atcttttgct tctttagagg
    12421 ccacagctgc acttaagact actgtatctc cataacggac taaaacggct ccgtttgctt
    12481 gttttgctag ctgaccgact tcgatttgta agggacggcc gccccatgtc gttttgaata
    12541 cttgtttttc tgacataact tctccttttc cttctcgtga aagcaagacg ctactaaaca
    12601 aatgaaaact gccgaaagcc gtcttttgag cagctttcat ttggttagta ggagtccatc
    12661 tagcttgatc acggaatttt acttaattga tatacgagta aaaaaagtga gattcatgtg
    12721 aatcccactc tttttgacta aaattaacga cgcaagccta aacgtttgat caattcgcgg
    12781 taacgttgaa cgtcagtttt acgtaagtaa gctaacaagt tacggcggtg accaactttt
    12841 ttcattaggc cgcggtatga atgatggtct tttttgtgca cgcgtgcatg ttcattcaag
    12901 tggttgattt cttcagttaa tacagcgatt tgtacttctg gagaaccagt atccccttca
    12961 tggcgagcgt attcgttgat gatttcattc ttgcgttctt ttgaaattgc catttctttc
    13021 acctctttcg attattcccc tgcgactgag taaaacgttg gtgattcgct taaccaagtg
    13081 gcaggtcatg tgcctagagc acacagctat actttacctg aaaccgggtt gaaaatcaag
    13141 tagttaatca ttaagaaaag gtagttttca aacaatctta ctactacttt tccatttttg
    13201 tggtaaacta taatgcgaaa atagacttga aacacagtct tttaagaaag gggtacatat
    13261 tccatgatta caatggatga tatcattcgt gaaggaaatc cgaccttacg cgaagttgca
    13321 aaagaagttt ctcttccatt aagcgaagaa gatatctctt taggaaaaga gatgcttgag
    13381 ttcttaaaaa acagccaaga tccaatcaaa gctgaagaac tacacttacg aggcggtgtt
    13441 ggcttagctg ctcctcaatt agatatttct aaaagaatca ttgctgttca cgtaccaagt
    13501 cctgacccag aggcagatgg accttctcta agtactgtta tgtataatcc taaaattttg
    13561 agccattctg ttcaagatgc ttgtttaggg gaaggtgaag gctgtttatc tgttgatcga
    13621 gaagtaccag gatatgttgt tcgccatgcc aaaatcactg tgtcttatta tgatatgaat
    13681 ggtgaaaaac acaagattcg tttgaagaat tatgaatcga tcgtcgttca acatgaaatc
    13741 gaccatatca acggtgtgat gttctatgac cacatcaacg atcaaaatcc atttgcacta
    13801 aaagaaggcg tattggtgat cgagtagaga attggcaggt tccttcgata ctatgctaca
    13861 agaaagcttt ataaaaaagg ggagtgctca aaagctgcac ttcccttttt tatgtttctc
    13921 cactaatcga aatttagata gacatctaga aatcgcaatt ccaaaaaatt ctgtgtattg
    13981 gatacgcatc ttttcttatt ttttcttatt tcttccatat gggtgtttat ctcagagatg
    14041 atagaatagt ttctaggata aaaagtagca gctacgatgt tatccttcgt agaggattcc
    14101 tgcttcagct agtttttgtt tgatgttttt cagcatatgc ttttctgggt agcggatcgt
    14161 atgcagatgg atgccgcctg ttaattcgga taacaaagta gcattacttt tttgataacg
    14221 tctcataaag gaatcgatat cttgtggcgt tttgatgtgc aaagttcctg ctaactcacc
    14281 gtaaagggga tgttccacaa ttacatcaat gatttcacca ccattttcaa cgattagtct
    14341 cagttcttct tctgtttgat cttttccatg ctggacagcg attttactga tgtgcccagt
    14401 attggtttct tctgtttcga ggatataacc tcttgctgtt gccacgatac ttttacctgc
    14461 agctcgtagt aaagcaatat cgcctacaat gatctgacgg ctgactccaa aagttttcgc
    14521 aaacttgcta gcactcactg gtttttctgt atttgccaag gtttgcatga tttgttttcg
    14581 ccgtgtctct ccttcgatca cacttattcc tccttcattt tgttttggta ttcgcgcgag
    14641 tgtttcatca aatcaacata cgtgtctgtt attgtttcct tatatccctt atttttcagc
    14701 agactaacaa ctttatccaa tacttgctgc tctctttttg catcataaac tgcttggttt
    14761 tcttcttttt tcacttgtcc tattttagtt accgtatcca ttcttttttc taataaagca
    14821 accaactctc gatcgatcat atcgatctta tgacgtaatg tttcaagaga ctcttctgtt
    14881 agttcttcct ctactgtctt gatgatacga gcaggatttc ctgcaatcac tacattgtcg
    14941 ggaaaagatt tggtcacaac cgaacctgcg ccgactacta cgttgtcccc tagagtgaca
    15001 cccggcgtga cgataactcc tccgcctaac caaacattat taccgatttt aatgggtttt
    15061 gcgtactcca gaccgctgtt acgtttcact ggatgtagtg gatgcgtcgc cgtgtaaagc
    15121 tggacattcg gagcgaacat gcagttatca ccgatttcaa tcgtgctgac atctaaaaat
    15181 gtacaattga aatttgcata aaaattctcc ccaacaaata tattatatcc gtaatcaaaa
    15241 ttgataactg gctccatata gatttttttc cctgtacggc caaaagtctc tttcaacaat
    15301 tgggatcgca gttccgctga ttctgcttgg ttgatgattt ggctttgact tcttgcaaac
    15361 atacggtcgg caaccagctc aggatcattg gcaaaataaa gctcgcctgc aatcattttt
    15421 tctttttcgg ttttgaattc agtcataatc tgctcctaat tcttgtattt ttttgaaaac
    15481 aaccgctccg tcttcttgaa taaacgtata aggctccgct aaataaacag gcgtttgatt
    15541 gattactaag attttggctg acggctggcg aaactgtacc agatcacaaa acggatgaac
    15601 ttgaaaactc gttccaacaa tgacgatcag ctctgcttgg ctgacggcat aagccgcctg
    15661 ctccatgact ccatcttgaa acccttcacc atataacacg atgtctgggc gtatttgtcc
    15721 tccgcatgct tgatgtttgt cgctgtgaag atattctttc cagtctaccg tttgttgaca
    15781 ttttcgacaa tgacattgat acagactccc atgaaaattg acgagttgcg ggcttttagc
    15841 ctttgcgtgc aaaccgtcga tgttttggga aacaacccaa acattttttt ctttcgctag
    15901 atgtgctatt tccaaatgaa tgatattggg ttttgcttca ggatgataaa tctttttgac
    15961 aaattgatag aatttatccg gttcattcac cattgcttga tgactcagca agtattccgg
    16021 ctgctccatc ccgtggtaga ttcctgacaa agatcgatag tctggcactc cagaaggtgt
    16081 ggatacccct gcaccggtca aaaatgtaat ttgctgataa gctaatatct cttttgctgc
    16141 ttcgtctact gttaattgtt tcatgttttg tcacctcact ttccattata gcccatactc
    16201 gaacaaattt attgttgaaa agtcagaaaa atgggaataa aaaagtgtta tgggcatttg
    16261 agcaatttat cacaatgttc actgacaaaa gaatgaaaac gtgttacaat actgctgtat
    16321 aaaagtgagg tgaatcgata tgttaccatt ctttatttat tggggcgtta ttctggcttg
    16381 tatcgcctgg ttagcgttaa gcgtttattt ctctgttttt tatcttgtac gcaaagaaaa
    16441 tggaaatctt tgggcttttg ctttattcaa cgtgattgcc gcaattgttt tagccattac
    16501 attagccgta tatcgaacat ggggctgggg aatcacccaa tactcaagtt tgatttatct
    16561 aatattagcc atttatggcg tcgttgttct tttgcaagcg atcctaggac gtgagccaaa
    16621 gaaagcggca gcttaaatga tcgagatgga actggacaca ggaaattttc tgttctagtt
    16681 ctttttttat tgtattacat acatttttgt gtataattat actatcgttt gcaatggata
    16741 gatgattcac attttgattg ttttttcggt aaaagtaaag atttctatat ttatcagtat
    16801 tttttcaaaa accagcagtt atagattgac aaagcctctc gagtatcgta aacttttttt
    16861 gtataaataa ctgaatacga gatgcctcaa tcaatgaggt agaggtcgcg agaatcatta
    16921 accctgtgga gtgaagcaaa catggagaag caggaatagg gaggatcgcc gaaatgtgca
    16981 cttttttgct tggagtgtat gttgggacgc aagttaagag cttgcggact gtcttagcag
    17041 tgatgctaag ttgcgctatg ttttgtgaga ggtttatcac cttatggaat tttagcggcc
    17101 tttttatatc tataaatcgg tcgcttttta ttttttcaga taaagcttta ccgcatttca
    17161 tctagaccgc tcgtgtatca tataatcaga aagggagaaa aaaatgaaaa aaaatatggt
    17221 ttcagttgcc gtactatttg cttttgtctt ctcactattc agtgtgggat ctctggcaaa
    17281 tgcagatgaa aaaacaccga gcgatgagtt tcgcgtaggt atggaggctg ggtatgcacc
    17341 cttcaactgg tctcaacaaa cagatgagaa taatgccttg ccaattcaag gccaaaatag
    17401 ttacgccggc ggttatgatg ttcaaatcgc taaaaaagta gcagatggtt tagggaaaaa
    17461 attagtcatc gtccaaacga aatgggatgg tctggctcct gcccttcaat caggcaagat
    17521 cgacgcgatc atcgccggaa tgagccctac tgctgaacga cgaaaagaaa ttgattttac
    17581 cgatccttat tacgaatcac aattagtagt agtagttcaa aaagatagca aatatgcaaa
    17641 agcaaaaagt ttagcagatc tttctggagc aaagatcact gctcagttaa atacattcca
    17701 ctatactgtg atcgatcaga taccagatgt gcagaaacaa caagcaatgg ataatttctc
    17761 agcaatgaga acagctttag cttctggaat gatcgatggt tatgtcagcg aacgtccgga
    17821 aggtgtaacg gcaactagtg tgaacaaaga cttggaaatg cttgaattca gcggtgcaga
    17881 tggcttccag acaaacccgg aagatgttca gatttctgtt ggtatgcgta aaggcgaccc
    17941 ggatatccaa aaagtaaacc agattctttc tggcatctct aacgatgaac gaaccaaaat
    18001 tatggaccaa gcagtcaaag atcagcctgc tgcaactgat agtgaagaaa aacctggcat
    18061 catttctgat ttcactacga tttggaaaca atacggcaat atgttcttac gaggtgctgg
    18121 acttaccttg ttcatcgcat tgatcgggac agttgtcggt actacacttg gattactgat
    18181 tggtgtcttc cgttcggtac ctgaatcagg aaatgcactg actcgcttct tccaaaaaat
    18241 cggaaatgca cttctttcta tctatgtcga agtattccgc ggaacaccga tgatggtaca
    18301 agcaatggtc atcttctacg gtctggcact cgcttttggc atttcattga accgaacgat
    18361 tgccgctttg tttattgtct ctctcaatac tggagcttac atgacagaga tcgttcgtgg
    18421 ggggattttt gcagtagatg aagggcagtt cgaagctgcg caagccattg gtatgaccca
    18481 tggccaaacg atgagaaaag ttgttattcc acaagtttta cggaatatct tgccagcaac
    18541 aggaaatgag tttgttatca atatcaaaga tacagcagtt ttaagtgtaa tcggcgtagc
    18601 tgatttgttc ttccaaggaa actctgcttc cggtgcgaat ttccaattct tccaaacatt
    18661 tacgatcgtc gggatcatct acttagtcat gacctttacg atcaccagaa tcctgcgggc
    18721 ggtagaaaag aaaatcgatg gtccttcagc ttataccaag cttgaagaaa tcgacaattc
    18781 aaatttgcag gaataaggag gaagaatcat gaatgaaaaa attattgaaa tcaaacatct
    18841 aagaaaaagc ttcggtgaaa atgaagtatt gaaagatatc agcgtaacag tcaataaagg
    18901 tgaagttgtg acgatcatcg gttcttccgg ttctggtaaa tctactttct tgcgctgtat
    18961 caatttactg gaaaaaccaa caggcggcga gatcatttat aatggagaaa atgtattagc
    19021 tcctaaatat aatttaccta aatatcgaac gaatctaggt atggttttcc aatccttcaa
    19081 cctgttcaac aatatgaatg tcttggaaaa ctgtatgtct ggtcaaacaa ctgtcctgaa
    19141 acgagataaa gaaactgcca aaaaagtagc aatcgaaaat ctggaaaaag ttggtatgga
    19201 tcgttatatc gaagccaaac cagcacaatt atctggtgga cagaaacagc gtgtcgcaat
    19261 tgctcgggca ttatcaatga atccagatgt attgctattc gacgaaccta cttcggcgtt
    19321 agaccctgaa atggttggcg aagtgcttaa tacgatcaaa gacttagcac atactggctt
    19381 gacaatgctt atcgtgacgc atgagatgga atttgcaaaa gatgtatctg accgtgtcat
    19441 ttttatggat aaaggtgtga ttgcagaaga aggtacacca gaagatatct ttgtccatcc
    19501 gaaagaagaa cgtacaaaag aattcctttc acgtatttta aatgcttagg atcaatagct
    19561 gattgggaca aagagctgcg gtgtttaccg cagttctttt ttatgaatta ctcataaaag
    19621 gtaaatttct gaa
//
LOCUS       DBBGSP010000053        19413 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000053 DBBGSP010000000
VERSION     DBBGSP010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.053"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(343..2313)
                     /locus_tag="ACIZE9_002261"
     CDS             complement(343..2313)
                     /locus_tag="ACIZE9_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094091.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            complement(2328..3194)
                     /locus_tag="ACIZE9_002262"
     CDS             complement(2328..3194)
                     /locus_tag="ACIZE9_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094092.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            complement(3184..3417)
                     /locus_tag="ACIZE9_002263"
     CDS             complement(3184..3417)
                     /locus_tag="ACIZE9_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGC6094093.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            complement(3429..5591)
                     /locus_tag="ACIZE9_002264"
     CDS             complement(3429..5591)
                     /locus_tag="ACIZE9_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094094.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYQKEEKEAKAKK
                     AKVKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEEVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLLIPDDPNMFESEVEEATDFYSAVEQLEVATN
                     GLERLAETFNSSEEVEFEALAEDIPDEKEALFADDDKPTEAENQEVSIEETQTQIQTE
                     TYQQSKIDEKPESQSDKENYVYEVEKIVSESDVPKSLDADFLEKNFEQIIADKFQPVV
                     LDEINDPVDLNEEMLSIAELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGK
                     QMLADELLRIEQATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSSIIRKDYDMA
                     KQAYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQN
                     QEAKEVVVERIINSLKPEIENSLTDVQEKTLEIVEKTKSENEAEFHDTKEKITDVVVK
                     YFANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYRSNSEKLAEQS
                     EALREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTIL
                     GSSYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVIS
                     IDGKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            complement(5591..5857)
                     /locus_tag="ACIZE9_002265"
     CDS             complement(5591..5857)
                     /locus_tag="ACIZE9_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094095.1"
                     /translation="MREESKCKMVFDREKMLAHANEVLMSGLKGTELAKIMNMNVNQF
                     YDYRNGSKKIEKARLETLIKFEKAYVYMLDKQKRTIDRKKGVLQ"
     gene            complement(5943..6281)
                     /locus_tag="ACIZE9_002266"
     CDS             complement(5943..6281)
                     /locus_tag="ACIZE9_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094096.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNEQLG"
     gene            complement(6680..10321)
                     /locus_tag="ACIZE9_002267"
     CDS             complement(6680..10321)
                     /locus_tag="ACIZE9_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3659 domain-containing protein"
                     /protein_id="HGC6094097.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLIDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGQDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDENGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEDDEITLDQTHQELRNEMSGEDVSDRVHRELGNGASGESQSRELNSNFDNSA
                     IRNDTALKDRESLSKETDKEQSDVKKKFIPTPNINQTDKYETNNGLGMSKDNQSIREP
                     ELTNDNNRTNNSKSTSDNSGKSNQSTKKPSTAKSAVEYLSKTGKNVYTSADKALAKSP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            complement(10324..12273)
                     /locus_tag="ACIZE9_002268"
     CDS             complement(10324..12273)
                     /locus_tag="ACIZE9_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6094098.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKAEDKDNEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQM
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFR
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPKKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            complement(12315..13373)
                     /locus_tag="ACIZE9_002269"
     CDS             complement(12315..13373)
                     /locus_tag="ACIZE9_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HGC6094099.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLEERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            complement(13492..13947)
                     /locus_tag="ACIZE9_002270"
     CDS             complement(13492..13947)
                     /locus_tag="ACIZE9_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094100.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            complement(14531..15334)
                     /locus_tag="ACIZE9_002271"
     CDS             complement(14531..15334)
                     /locus_tag="ACIZE9_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HGC6094101.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            16377..17537
                     /locus_tag="ACIZE9_002272"
     CDS             16377..17537
                     /locus_tag="ACIZE9_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HGC6094102.1"
                     /translation="MKITEKNVNPKFEPTESNLKKFDLTVTLSNELVDSIVEMDAMPQ
                     KIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSSSSKHSRLKQVIEKLHQQSVIK
                     IQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSSIMPLLTNLEDHFTQYAFDQVV
                     NLTSKYAISFFQLFTKDFNLYLANRDNLTWSTKSLDRLKNPVFSIADLRKKFSIEKKY
                     KAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTYTNIKFLLTRTMSVPVPYKQEQ
                     RDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFLISSADLCDLKLMSRLQNKVYP
                     LYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYLEKSITSYLPYVNLYD"
     gene            17572..18339
                     /locus_tag="ACIZE9_002273"
     CDS             17572..18339
                     /locus_tag="ACIZE9_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HGC6094103.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFKDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LKIDFAKVRKGRNYNFAVQFNISSEFDEKPYREKKLG"
     gene            18529..18927
                     /locus_tag="ACIZE9_002274"
     CDS             18529..18927
                     /locus_tag="ACIZE9_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGC6094104.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(19172..>19413)
                     /locus_tag="ACIZE9_002275"
     CDS             complement(19172..>19413)
                     /locus_tag="ACIZE9_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HGC6094105.1"
                     /translation="PPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQNFNSRSV
                     KGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         5871 a         3688 c         2823 g         7031 t
ORIGIN      
        1 aaaactctcg ctttttcttc atcagtaaag tttttataca actgattaca ataatgaggt
       61 ttttgaagtt tctgaatacc tatactaact tcaaatcctt cttcatgttg aattaggatt
      121 acttctgtgt ctctacctag aaatattcga tctaaaattt ttatgtttgg tttcattatt
      181 taacctccac tataattatt tcactcagta aggtttcact ttatgaaatt tctatagttc
      241 tcttttcaca aaacgtacca tgttctctaa gactgttttt agtctcaaat atacatgttt
      301 tttcttatcc tttccttata cactcaaaat caaagataaa acttaaagaa taaactctcc
      361 aataacaaaa ttattagtca gatccactgg tctcctgatc tgaaatttat tacttcttcc
      421 tgttgtcaaa tactgtctca aatcaacaga aagtttttga tcatcttctc cttttctagc
      481 aggagcaact tttttttcat acttcattaa ctctccactg gtcatctttc caatgatagt
      541 gtaattaaaa tcactttcaa aactttggta aatttttcca tctgtattga atatatcagc
      601 tgtttcaata tcttctttgt attcattgtc ttctcctgaa ccgattgtat caaatagaaa
      661 ggcaagacga attccatctt cttcaagcat tgttaatctt tttttaatta gcccaacggt
      721 ttcaatagat aacttatcga agccgtgaat cataacaata tcatcttttt ttgcttgtga
      781 tgtgatgaaa tcaaaggtat ttaaaaattg agcttccata acattggttt ctgctcttag
      841 atcacctaag ttatagtaaa actgtaattt gtcactttta ccgatttctt tcagtgtcgt
      901 tctttgatta aacatcctag agaagctgtc taatgctgtt ctcaatgtgt cttttaatac
      961 aataatacga tcgacttctt tttcagtacc agattttttg gcttttgttt cagcattagt
     1021 caaatagcta ataaaatccc caagaactgg cattgtatca ctactgttca ccaaaagttt
     1081 tgaacgttct tcataattaa tatcccaaag tttctgactt atataaaagt tacctaattc
     1141 ttttttcaat aaaactctag ttgcagaatc taatgttctg cctgctaaca aataaaaaat
     1201 ctgagttagt ttatcgagat tccgtctata taaatcacca atgtcctttt gattaccaaa
     1261 aagctccaaa gagttaagac cttcttcagc caaattaacc ttttctatta cactgtttaa
     1321 cgaaggtttg gcaacaaatg ttctaccagt tggatcacca aagtaatcaa atttatttaa
     1381 gacaatatga aaagttcgtt tatgatttgc cattgcatta ttagcaatca attgccccca
     1441 aagtgatgat gctgagattt tttcatcata gcctttaatt gtagcgtttt tgtgtgatgc
     1501 cactaaaact ttacttgtaa aagaatcatc cagtgccata aaagctacac cacttgcgta
     1561 gctagtagac atagtgccga tagcccatcc attcgcatca tctaaacctt tgcgaattgc
     1621 atgatcattt cctgcaaaat ccgaactcat agacgtatac tcatagacat tcccgattgg
     1681 ttcacttaaa agtctatcaa acagatcacg ttgatctcct ccatatgaca taagctttaa
     1741 tccatacatt ttttcatcat acaaccgttg gagtttaatt agctgttcgc tgattttatt
     1801 aggagaatcg gatactaata ggatttctag cttccaatca ataattttat ttgccatgct
     1861 gtctagtaaa gatgctgtat tcaaatccat aatccgcata acagttttgc taatttcagc
     1921 atctgaattt tttccttcta aattattttc ataactattc gttgatcccc caacattctc
     1981 gtgcattatt tcttgttgat ctttttgtga cactggctta tctgcttcaa ttagataggc
     2041 ttttacccct tctactctca cttcaggaat agctttaacc atccaaccaa atccataatt
     2101 tctattcatt ccataagtat tcactaattt cacaattgtt ccccaccgct tacctgtcct
     2161 aatgtaagat ggtgtaaatt gataaccaac taaagatgtt aaatcactaa caaaggtatt
     2221 attcactacc tttgaatttc tagttttttg ttctttttta gtttttctct tttttttgaa
     2281 atttaatagt tgtgatctac ccataatttc catttaatct ctcacctcta tttcagtgca
     2341 taaatatcag ataatatttc ttttgtttgt ttagctgaca actgagtgac actataataa
     2401 agtcctctac tcgtatagtt ttctaaacgt tccacacctt catccaatac catcttagat
     2461 tgagatttca agataagata ttggattact gttgttttca caccatcaat atattctgat
     2521 acaaatcgtt cttgctgatc tattatgtca aagactgctt tgttactcct tgcatttcgt
     2581 ttttgtattt tcatatttcg agtttgtctt tccgtattct gaggttgaga tgaagtgatt
     2641 ttgatttcag ctaaggaacg atctctggta ttttgatatt gtattgattt cgattcctga
     2701 gccataactt cttctggaaa agcggttagt gatgtagccc catctagatt gaacattaat
     2761 gctacactcc catctcgata tacgattgtt ccatcttgtt tcacttttaa aatctctgtg
     2821 cctcgaaatg gtttcttttt ccccatagat actcttgctg aattaactac tgatttgaac
     2881 agtctaatag aaccagaaat caatgaacca ctagatggat caataaacat atactggcta
     2941 attagaataa gaaatccaat tatcattaat aacgttggaa caaaaataaa tttcagttta
     3001 atcgtatcag aaactaagta aacaattgat ccaagaacaa cgactgcaac aactatagct
     3061 gatacaatta atctttttgc tgtaacagaa taggtgctat tgacatgctt ttcaagccat
     3121 tcaactctga caattgtttc agaaggtttt tgatgtaagt tatgtttaaa tccatagttt
     3181 gagttatctg ccatcagaaa tacttccttt cacgttcaac ttacggtaaa cacctacagt
     3241 tatcactatt gcaacaataa gcaagccaat taaagatatt gacttgctca ttgtctcgtt
     3301 cgtttgtggt agttcattta cctgatacac gagctgtgct tcctgtaagt gctgagaaga
     3361 ggtcatgttt tcttgattgt tttgaattac tggataaact attttttctt ctcgcataat
     3421 agccctcctt agttattatc agataagtga gcttgaattt tgtactgatt tccgtctgga
     3481 gttttcacaa ctgctttttc tccatcaata gaaatcactt cagccttagt tgttttccca
     3541 tcaatactga tgacaacatc tttcccaact ttgaactctg tagttggtgt tgcttcatag
     3601 ctactatttg ttgaagcaga gttcgtattt gtcccaatcg aattttccac tctcgaaata
     3661 gatgtttgag tttgagcctg tgcttgttga ttattatgac taataaagta ggacgatccc
     3721 aagatcgttc cgcaagccat tgcagcgaca gaaatgatag tagccatctt tttacttgta
     3781 aaatcacgtt ttgaacttga ttgattttct gtagcaactg ctaatgattt cgttttttct
     3841 gccatttgag ctagatcact tcgggaacga gataagtctt ctcttaaagc ttcactttgt
     3901 tctgccaact tttcgctatt tgatctataa ccctctgcta aatctttgac ctctttcatt
     3961 cgatctttat attcttcgat agttttttgt tgctctacaa gttttgtttc taattctttc
     4021 gtgttgttag ctacttgctt ttcaacttct tctttgttcg caaaatattt gacaaccaca
     4081 tctgttattt tctcttttgt atcatggaac tcagcttcat tttctgactt tgttttttca
     4141 acaatctcta acgttttttc ttgcacatct gttaatgagt tttcaatttc tggtttcaat
     4201 gaattgataa tccgttccac cacaacttct tttgcttctt ggttttgttt caatgcatcg
     4261 tttttaatag attcaattgc ttcttggtac tgttgatcaa gactttcttc agttgctttt
     4321 ctatattcat cttcttgttg tttaacttct ggtaaatgtt cagcatcata ccgttgctct
     4381 agtttcttta gttcagcatc caaataagcc tgtttcgcca tatcataatc tttacgaatg
     4441 atactggatt tttccatcac taaatcatca atcttagatg cttctgcttc gtagctctct
     4501 ttagcaaccg ataatgtatt tgtaaactga ttttgaccat ttaatgaggt tgcttgctct
     4561 atccgcaaaa gctcatcggc taacatttgc tttcctttga ggatcaattg ctccttcgtc
     4621 ttatttaatt cactgttgat tttattatta gcgatagaaa tacgagcatt catactctct
     4681 ttagctaaaa acagcaatgg tttcaactca gctatggata gcatctcctc gtttaaatca
     4741 acaggatcat taatctcgtc taaaactaca ggttgaaatt tatcagcgat gatctgttca
     4801 aaattttttt ctaaaaaatc agcatctaag cttttcggta catcactttc ggatacgatt
     4861 ttttctactt cataaacata attttcttta tcactctggg attcgggttt ttcatcaatt
     4921 tttgattgtt ggtaggtttc tgtttgtatt tgagtttgtg tttcttctat gcttacttct
     4981 tgattttctg cttcggttgg tttgtcatca tctgcaaaaa gagcttcttt ttcatctggt
     5041 atgtcttctg ctaaggcttc aaattcaact tcttcagaag agttgaaggt ctcagcaagt
     5101 cgttctaatc catttgtagc tacctctaat tgctccactg cgctatagaa gtctgtagct
     5161 tcttcaactt ctgattcaaa catattagga tcatccggaa taagtaataa ttgaccacta
     5221 ctatccataa aacggacacc tgctaatagc ttctctttaa atttttctgg tagatcagct
     5281 acataattca aacttgactt caatagaacg acatactttt cggaatcgag aatagcatca
     5341 tcctcatcta taacttcctc actgttgagc ttttgtacat cttcaattac catataattt
     5401 ttctttggta aatctttggt cagcaacgca tcgaattctt tccatacctt taccttagct
     5461 ttttttgcct tcgcttcttt ttcttctttt tggtacactt cgagtaattg tggcttcaaa
     5521 gagagtgcaa ctacaggaac tgtttctgcc acataattaa tagattcggt aatatctttg
     5581 aattttgcca ttattgtaaa actccttttt ttcggtcaat agttcttttc tgtttgtcta
     5641 gcatatatac atatgctttt tcgaatttaa taagcgtttc aagtctggct ttttcaatct
     5701 ttttactccc attccgataa tcatagaact ggttaacatt catattcatt atctttgcca
     5761 gttcggtacc tttcagaccg ctcattaata cttcgttggc gtgagctaac attttttctc
     5821 tatcaaaaac catcttacat ttactttctt ccctcacttc taaactacgc ttggagcgta
     5881 gttttgtggt aaaaagtaaa ttgaacaaat cggcatatta tccaaatttg ttcaattcac
     5941 ttttaaccta actgttcatt ttttggaaat tttgaaacta gatagatacc aacaactgga
     6001 ataagtgctg atataatatt agctttttgg ttcaaatcat tacctgtttt agtacccatt
     6061 gtgtaaagca taacggttgt aattacaggg ataataaaga ttgcaataat cgccccaaca
     6121 tattttaatc catctcccca ttttgcatca ccaaaaaatt tcattgcagt gaatcctggt
     6181 ttcaacgaaa aaacgaatgc caagaaatac aaaacaactt gtactaaagt tttcatatca
     6241 ggcgtcattc cgctaaccaa atttttaata gaatcgaaca tataaaaacc tcctttttaa
     6301 tatttttaat aagttaatta tatcatcgac aaatcttatt tgttcacttg tcaatgatct
     6361 aactaagaaa aagacgtctc gatatttaca tctttatgtt atcataataa cataaatttt
     6421 tgatgattaa aagagatttt ccattaaatt atttcatttt ttttattggc taaaaatgct
     6481 ggtttatcaa gtttttgttt agataataat tctgttcttt accagcataa gcccttttta
     6541 attaaacaac tttgaacagt aaatatttaa ttcatttata gataatttta aaaatttttt
     6601 tgcataaata gaaatttttc ttgacatctt cagttaaaaa taaaagtaaa aagaaggagc
     6661 aaatcaatgc tccttctttt tattcgtctt cagacttatt ttcagttgat ttctgattac
     6721 cgtattttac aatatagtcc ttgactgaca tggtagattt cttcactact ttaccagtct
     6781 tggatgctcc tgtagcagta gccttggcaa ccttagccgt tcctttacct attttaatag
     6841 cttcgttttt agcttcatag gttatccctg ctagactacc ttttggagat tttgctaaag
     6901 ctttatctgc tgaggtgtaa acatttttac cagttttcga tagatattca acggctgatt
     6961 tggctgttga tggtttcttg gttgattgat tagatttccc tgaattatct gaagtagatt
     7021 tagaattatt tgttctatta ttatcatttg tcagttcagg ttctctaatt gattgattgt
     7081 ctttcgacat tcctaatcca ttatttgttt catatttatc tgtttgatta atattaggag
     7141 taggaatgaa ctttttcttc acatctgatt gttctttatc cgtttctttc gatagcgatt
     7201 ctctgtcttt aagtgctgtg tcattccgaa tagcactatt atcaaagtta ctgttaagct
     7261 ctcttgactg actttcacca gatgctccat ttcctaattc ccgatgcact ctgtctgaca
     7321 catcctcacc actcatttca tttcttagtt cttgatgagt ttgatctaat gtaatctcgt
     7381 catcttcatt ctcaggaatt gcaacagcaa ttggcgtatg ccgttgttgt tcgagttctc
     7441 tatttcgatc tgccacaagc gcatctctcg tctcaatgat attcccattc tcatcgacta
     7501 aatcgccatt cacattatat ccatcgctgt gtttaccaag tttattacca aactcatcaa
     7561 caagatttcc atcttcatca actaaacgcc ctttttcgtc aactaaacgt ccgttactat
     7621 cctgaccaaa atcaccattt agcaacctgc gtccattttc gtcaacaaga tttccatctt
     7681 catcaactaa gcgacctttt tcatcaatta aacgtccttc gctatccata ccaatattac
     7741 catcttcact atcttccaat ggtttaccat tagtatctat aaggtttcca tcttcatcga
     7801 tcaaacgccc tttttcgtca ataaagttgc ctttagcatc tttaccgtat ttactatctt
     7861 ttaatatttc accattttca tcgacaaagt ttccgttttc atcaaccata cgtcctaaat
     7921 gatcaatata ttgttgggag ttattacgta gttgatcttg acgaactaaa tctttgaaag
     7981 aggtattatt gattgttgaa ccaactccgc caccgttgaa tgacattcct tctggtgttt
     8041 caggaattac tttatcagca atggacttag catcagcatt gctatctccc atattgttca
     8101 aacgttcagc cattttttgc gctccaactg ctccaagacc tcctgcaacc atatctttta
     8161 ctgagctgtt gccaccatca taatagggat ttttagctcc ttggcttttc ttgattgctt
     8221 tagaaacgcc gtccacaact cgcacagcat catttctatt accaaataat aacttagcac
     8281 gttcatcaaa cccaaacgct acttcaagtg gtaagccaat aagcatatta atcaaattat
     8341 ttactttttc gcctttttta aaaactaaaa gatatcctac acctaaaatc atagcagatc
     8401 gaacaatatt tgctacgcca tcgccaacta atgtattagg aatgaatccc acagcagtat
     8461 caccaaatgc acgaataaaa gtaatcagaa agataggtaa ttgtagtccg atcagagatg
     8521 ttgtaacaac acctaatgaa attgccatca cacctgctcc tgatgcaagt gatcctgtta
     8581 gaactacttc ccaaatccga ataaattcac gtttaaatgc tttcacgata ttcacattga
     8641 acatcgccca agcacatgct aagtaaagaa ctgctaaaac gattgattca gcgttcatcg
     8701 ctagccacga gccaaactta cccatcgctc catgaccaac taaggatgct gtacgccatt
     8761 ctgtttttac tgttgacata ttcttagcac tgccttgaat tcctgaagga gcgatattat
     8821 acgcataaaa cttagctcct gatgtatcaa gtgccgattg gagcaataaa gctaccgact
     8881 gtgtgctaaa agttgcattg ttagcaacgc cccaaggttg agtagcatca aagttatgcg
     8941 ctgttccttt tccatcaggc ttgcgattgt cgtctgtcac attttgattt gctgaccaaa
     9001 tatatccatt taaattggtt ggtttcttaa ttgcacttcc ttcttttcca tcccctaaat
     9061 tatagcctgt ccaaacagca ggcgctcttc ccatataagc atcattttcg gcgacattaa
     9121 catcaccggc ataagtatta atattgaaag tatcattcga tgaccattct tttaatagag
     9181 ccataccgac tgaattagaa tctagatcat tattttgtct ggcataactg ctagtattga
     9241 tcgctcttat cattgcagat tttttagatg gttcataatc tgtatcaacg aacttgattt
     9301 cggatgtagg ctttccgtca ggtacatcac caccagtatc agatgatgga gcaagatttt
     9361 gagtagaagc ccaaagtctt gtgttaatga tgtagtcaga aacaacattt gttggtatat
     9421 ctccatcttt ttttgctgac tggatgccgt tgatataaac tcccaatagc gatcctgcca
     9481 ctggtaagaa tataaacaat acaaaaatac gaacaatcca tttttcaagt actggtgata
     9541 atcccttcga gttaacacca tctttcgaca ataatttcat tccttgataa cctagtattg
     9601 ctgtgaaaaa gagcatagat aagcttgcta tcgctttaaa taattcatta tttaatccca
     9661 aattgttaag caagctagtt aatgctttag ataccggatt agatacatcc gatccacctt
     9721 ctccccaccc cataagagaa aatatattca tactcatgaa aaattttcca aggagttcat
     9781 ttatggattc agcaatatta gaaaggatta aactaattga tccgataaaa ctaccaatcg
     9841 tcctaccaat acttcctaga atggatgatg cttgacttgc aatagcattt cctgagactg
     9901 tttcaatata tccgtagtaa ctataagttg ctaaagtaga tgctagttgc gtacctgcat
     9961 taccccctgc aatcgaatta ccttgtttag aaatgtcaga ataagggaaa tcggcactga
    10021 taccaccttg tcctaacaaa ttcatttgtc cagttttagc ggcactatca ttgacttctt
    10081 tatctcccat taggatacga gcatatagtg tccacattcc ttgttctgcc ggtttacttt
    10141 ccgcataagc aacgttctta tttataactg tttcttgttt gctatcttga ttgtcaggag
    10201 ttggatcatt cattccaaaa ggagcgccta aagtaactgc taatactcct ccaataacta
    10261 gacctcttac gacccatcgt tttattctaa ggttttgtag taaatatttc ttgaatttca
    10321 tagctacgcc cctccaatcg aaaatacaat cttgttttct ttactttcag caacggaagg
    10381 ctttgcaata atttcagcat tagaatcacc ttttccttca aacgctccgg cttcactcaa
    10441 cttaacatcg aatatttttg cgtttggata agtaattatt gcttcagtaa tcgcttcttc
    10501 aaactcagat tcaactaaat gcaagatatt ccttgcaccc cctgatttag aatcctcttg
    10561 tgaagccatg tcaaaaacta agtgcatgga gagatcgtct gcataaaaat tttgaccata
    10621 tactctttct ttcttaggtg gaagacgtaa atctatattt aaatgttttc gtactaattc
    10681 agcactcttc aacatttcat tataagcaat ttccagaaga gtttgttcgg ataaagccca
    10741 aaatggaact attcgtccaa atcggttaat aacttcaggc tttagacctt caccaatcaa
    10801 ggcttgtttg atccctgatg cgacttttcg gtattctctt tttagttcag tgctgtattc
    10861 attagaattt tccttgtttg taacacgaga tagtgagcta tatcggttta acgaatcgaa
    10921 catctccgca cctgcatttg ttgtcgcaaa taaaattgta tttgacaatg aaacggtgtc
    10981 gtgaacttct cgatcatccc atcctctttc agtaaaactt atcctacctt catctaaaat
    11041 tgataaaaag gcatcgagtg tttctacacc agctttctca tattcatcac acacaataat
    11101 cgcagaagga tcatgcctta catgagtacc tataagtcgt ctaaaacgca ttgcatcatc
    11161 tttggttttg tagtccggca tattaactaa gagaacttta ttttcatcgc cataaagtcc
    11221 tcttgccacg gctttagcca ttgcagtttt accgacccct gttgatcctg taaacagagc
    11281 agttgctttt ggttgctttc gacctttaaa acgatcaaat ccaagcttca tacgtttaaa
    11341 caacattgtt atagtataaa ctgctaacgg ttgtcctttt atggacttta attcctcttg
    11401 aagtttttcc atatcaaaat cagaatctag ctgaatatta tacttaccaa atatttgcaa
    11461 tagactttct cgattataag catttccgtc tactcgatct tttgcaatca aatcctccat
    11521 tacagcaatt gatttagccg gttcggacaa atcctcacga taaagtttgt ttgcttgtac
    11581 gatttcttga agtaattcat caggaatcct ttgcgataat ctaaaagaag cctgaggatc
    11641 atctttaaca gaggatgtat ttagccattg tctcaaaata tcgacgacaa catcgctttt
    11701 tagttcattc aattctaacg gttgtagccg tctccctaag gcatcatctc ttttgatata
    11761 gttttcatat tcttttcttg tagtagcggt aatcatttga agtgattcat ttgctaacgg
    11821 ttcttttagc gaatcacccc caattttatt gccactccca aaagagctaa caactttatg
    11881 aaactcgtca atgaagagga caaattcatt atctttgtcc tcagctttta aaattcgctc
    11941 atattctttc aatcttggaa ttaatgtttc taaacgtgtt tggaggacat catctccccc
    12001 aacacgcaat tgtccgattg ataatttata tacttgtact ttctttccat cttgtcgctg
    12061 tctttcagcc cattcacttg caagtgctgt tttacctgtt ccggcttcac ctaacaagat
    12121 agcttgcggt gtttccggtc tattcaagat cagtgacaac tcatggagtt cgtcatcacg
    12181 tcccactaac ttatgttttg gtggtttcat tggtgtgaga gcatgattaa attcggtttg
    12241 aatattctta aaaaactcgg tactattttc catctgtttg tgttcacttc ctctaaaata
    12301 agaataattt acttctagtc agtcaaagtt aggtacttaa atgtcgtctt catgtctcca
    12361 aaagaatctt tgttaaagtc agcatttttg tattgatcaa tcaatttttg tgtatcattg
    12421 attgctttaa tttcggtctc cattcgactg tctagttgac gaatactttc ttgcgaatct
    12481 ttatcgtcag gattttgttg taaacgttcc agatactcag cttttgtggc ttcaattttc
    12541 ttgatgttag tatttgaagc atttaactga tcttctagct tatttacaac attattctta
    12601 cttgtaactg ctacaacttt tgaataatca atatcgccat ctttggtaag aaagcttcct
    12661 tgatagacat tagttgaatc tgaatatgga tttattctga aattgatatt atcaggagta
    12721 ttaacaggtt ttgctttttt cccaaaagaa attactcctt cattattaac atcattcata
    12781 gaatattgag aaagtgcttt tgtaactgaa tctgcttcat tcacattgac tttggtatca
    12841 tcgtcagctg tatcatcacc agaaattagt gatacttggt ttgcaataaa aacttgataa
    12901 gctctttcct ctaatttacc ttttaggaat aagaaagcat ccccatcagt acttaacatc
    12961 ccatagctca tttcaagctt cttaggacga tctttttctt ttgttgccat atataagtta
    13021 tagttttttc cttgcgtaga taacaacttt ctagcgtttt gggagtaacc aagttttact
    13081 actgttacat ctctattttg atctgtccac acatctgaaa tagtgatttc tgctcctgat
    13141 cgagcaaact ccaatgaaga ccctataggt gttgtattgt tcacgagata ataattatag
    13201 tttcctaatt gataaatgta gctacccaag cctgttaata aaaaaagcac tcctagaaaa
    13261 gttgcaagca taatgcgtaa tccgtgacgt gttctcttat ccttatcacc aagcaaccct
    13321 ccaataatac tgtattgatc tttggtagat gttgaattga cgtttttttc catcagtttg
    13381 tctgccccct ttcataaaag agcaaacaat cagacgtttt ttcggtaatt ctaggttcgg
    13441 gattttgaat catttcggta tattcttccc cattaatatt taacacaaaa attatcttcc
    13501 tttcttcgtt cctttctttt gctctttatt ttccaaataa tcaatgattt ttgctattgt
    13561 accaagatag taattcccct cagctttgtt ttttcggatt ttgctaacca ttggagtagg
    13621 tacaatctct tcatctctca attcactgaa agatttttta cctagatatt ttccaataac
    13681 agattttaaa aaacgttcaa aatctttctc gtaagttgtt ttcttgcctt ttagttcatg
    13741 gttcatattg tcaacgactt ttgcggtttc aataattgtt ttagttctca gcttaataat
    13801 ttcatctgga attttcaatc ctcgtaattt catcgttgta ctaactggta acccatgctt
    13861 tactgcatca gcaatactaa aactttttag atcatctagt aagctctcca tatagttaac
    13921 aaattcatgc caattaatag cattcattgt ctcacccctt cattttttta aaatgaggtt
    13981 cgggcgtaac acatttatgt tattataata tcataataac ataaataaat caatcagcaa
    14041 atttagatat cccttaaagt atcagcaatt attcaacaag atatttattt tagctatttc
    14101 agtcatcata aaagactaat tagcaataaa ataactaata ttatccattt atcagacgaa
    14161 aagaaaaaac ttatctaatt actctatatt aacttttaac aaatagttga cttgtccaaa
    14221 aatgttacct tcaatctcac aaagatatta agatgtttcc taccaaaact gatatcaccg
    14281 gactttttat tctgtgttgt ccaaaagtgt tacctttagt cgatcaacaa attaaaaaaa
    14341 attgtttttt tcttgacttg tccaaaagtg ttacccatag ttgttaaaat ttgtatagat
    14401 tagccattct ttcgaatatt atttagactg aaacttgctt acaaaaaaac ttcttgcatt
    14461 tattgtccaa aagtgttacc catacttttt taaagaagca ggttgtatta aaattacaac
    14521 ctgcttcttc tcaatcttct tctaaccaat tatgcattga aatggttggc aagtttgatt
    14581 ctggctcact aaaagtgaat ctgagccgat caactcttct tcctttcttt gcatagattt
    14641 tttcataatc aaaagtttca aatacctgta ttccgttttc atcaggagct aaaaattctt
    14701 ctttcgcctg ctctagtatt cttttgtcaa tatttgtcat tctataactt gaaggtatac
    14761 ttaatgctct tctaaaatct tcaactttga ctacccaata accatttcgc cactctttat
    14821 ttctgtattg catgagatga cgatacaatt cttttgtgta gctacttctt agttttgtaa
    14881 aattatcaag ttcaaaacga gtaaagtttt tgccaattga gtttaagata aattcaaatt
    14941 cctcatttgc cttaattgta actgtttcct tctgtttatc tatccggaat ttttgaaaaa
    15001 gccacagctg ttcatagacg tctgaatctt caaaacggta ggttaaagta cctagtttgt
    15061 cactcaaagc ttttaacaca gaataaaaac tgtccttttc tcttctgtcg tatttgacca
    15121 aataacgaaa gaggttgaaa tcaaaagtta cttctgctgt tccttgacgt ttcatttttg
    15181 ataaaatagc ccaaaacaca tccatttcaa caggcttaaa tcctcgcaaa gctgttgtat
    15241 tcagaccatt gttataacgc acaattgcat ttgtttgttc tgatactaaa tctacatcac
    15301 tatcaataat cttttcggta acttcttgag acattgatta ctctccaatc ttctttttgc
    15361 gctcctttaa tcatgttaat ctggtactaa ttaaaggaaa caattttttc tgcttgttac
    15421 ctaaattaaa tcacaactaa aggtaacagt caacaaagat ttgttactaa tctaattttc
    15481 tattttttcg ccttccaaat caagaaaacc gaaggtaacg tcttatccta gtgtgatacc
    15541 tcaaatgtcc acttttgtta cctttgctgt ccaaaagtgt tacccttact gtccactttt
    15601 gttaccttta ctgtccaaaa gtgttacctt tatacccctt taatacttac tctcccaaga
    15661 gattaagcct cccctaacag atatattaac agatatttaa cagatatatt aacagatatt
    15721 taataaagga ggattactcc tctcttattt caaaatctta aaaataaaaa atcttaaaaa
    15781 aaactaacac tatctaggag tttattttgc ttgtgtaact ttgaataatt gaaaaaaagg
    15841 aaaaggagga agcttcagct tcccctttta tttatattta taatatatat tttaatcttt
    15901 aaaactttag caaccttcaa aaaggcttta tatcaatctt aaatagattt tagggtggac
    15961 ataaagcgat gcgaacatgg acaaaaagcg atgtgaatgt ggacaaaaag cgatgcaaac
    16021 gtggacaaaa agcgatgtgg tattccgaat atatccaaaa aaagaaaaag tatgtgaatt
    16081 tatttctaaa aactagaaaa atatttgttt tttaattttg gtaattttta taatttcgta
    16141 tttttttgaa aaggattttt atattgaaaa tgttctaaaa tagcgatttc tgctgtctta
    16201 tcaatgaaaa ttgattaaaa aaataaaatg tgttttacag agattgagtt atgttataaa
    16261 tttacgatac atttcttatt gtatcgtatc gaaaacaggt ctatacttat tcaatggaat
    16321 cgtaccagtt ccaaattttt aagctcgtac caagcttaga aagaagaggc aatcgtatga
    16381 aaataacaga aaagaatgta aacccgaaat ttgaacctac cgaaagcaat ctaaaaaagt
    16441 ttgatttaac tgttacttta tcgaatgaac ttgtagacag cattgttgaa atggatgcta
    16501 tgccacaaaa aatttatctt tatgctatag gacatcttga ccctaaaaat ccgcctttta
    16561 ataatactgt taaagtatct aaaaaggctt tatttgcgtt gatgtcttct agttcatctt
    16621 cttcaaaaca ttcaagatta aaacaagtta ttgaaaaatt gcatcagcaa tctgtcatta
    16681 aaattcaaag aactaaacct aacggtaaga ctgaatacaa agtcatctca ccgctagaaa
    16741 ttactgaatt caatgatttt tctgatgcag tatctattaa atttagtagt tcaattatgc
    16801 ctttattaac gaacttagaa gatcatttta cgcaatatgc atttgatcaa gtagttaact
    16861 tgacaagcaa gtatgcgatc agtttttttc aattattcac taaagatttt aatctgtatt
    16921 tagcaaatag agataactta acatggagta caaaatcact tgatagatta aaaaatcctg
    16981 ttttctccat tgcagattta cgaaagaaat ttagtattga gaaaaaatat aaagcttttc
    17041 gagactttga aagacgtgta attaaagaac cgattgccca actgaataaa tacactgatt
    17101 ttaaaattga ctatgagctt atcaagaagg ggcatactta tacaaatata aagttcttgc
    17161 ttacacgtac catgtcagtt ccggtacctt ataagcaaga acaaagagac cctgcttatt
    17221 taaaaggcgc agaagataaa acagagaaaa tgaatcaatc gtacttgaaa gctatgaata
    17281 gcaaatacac taaattacta atcaaaaact ttttgatcag ttctgccgac ttatgcgatc
    17341 ttaaacttat gagccgactt cagaataaag tttatccgct ttatgatcgt ttatccaaag
    17401 atagaggatt tgaatcagtt gtcaatcacc tatcttacgt tgctactcat aaggaggatt
    17461 acacaataaa aaatactgtt aaatatctcg aaaaatcaat tacgagttat ttgccttatg
    17521 tgaaccttta tgattaacaa ctgaaaacat gcgtgaagga aggaaaaact tttgaaaaaa
    17581 gatgaactga caaagtacaa tgaggagttc ttagcaacaa ttgatatgaa aatggattta
    17641 aagtcgtatg aactttatca attgctgttc agttatatct cacccacaaa gctaaagaaa
    17701 acaggcgtag tagatttacc tgttaaagcg attattaatt acatggatgt tgatcaaaat
    17761 cttgaaacgg aactaaaaac catagttaac actttgcaaa gacaagcagt ttatgaaata
    17821 tcgaatctag acaagaaata taagacgtat actactgtat ctgctattga tcggattcat
    17881 tgggatttag aagagcatag tgtatctttc agtttttcag aagatgtaat tcccttaatt
    17941 gtctcaatca aaaagaagta tccgttcttt gtttttaaag acttagcatc ttttcaaaaa
    18001 aaatatagca tcgtgttata caaatatttg gcgatgtatt ataaaaaata tcttatcgcc
    18061 aaaaataaag gagattttga gaaagctgaa atatataaga atcccctgat tgaaatagtt
    18121 aaaattcgtg agattacgaa aacagaaaat gagtataaaa caatatcgaa ttttgataga
    18181 cgtgttttaa gggaatcagt tgaagaaatt aatgaaaaat caatgctgaa gattgatttt
    18241 gctaaagtta gaaaaggcag aaattacaat tttgctgtcc agtttaatat ttctagtgag
    18301 tttgatgaaa aaccttatag agaaaaaaaa ttaggttaat gcaaaatata tcttactcgt
    18361 ttgaagatgc ttcagacgta tgttaagata tgtagtgcct tgggagcaag gtattaatct
    18421 cctttagagg ttaattagct tgtgatcgcc tatcaatttt ttggtaggcg attctttttt
    18481 tgaaaccaaa aagcaaaaat tattttttaa ttagagaggt gcaatgcgat gaaatacttt
    18541 ttttgtgcag tattcgaatg gaaaggaaat gaatatgcag ttaaattccc agattttcca
    18601 gacttatata cgcatggtga aactttagaa gatgcttttg agatggcgca agaagtattg
    18661 gaaggatact tggtgctttt agagttgcaa gaaaaagaaa ttccatcgcc tacgcctgtt
    18721 caagagttaa atgcaagaat caagcgatct gagaatgtta atttatttgt cgtaaaagct
    18781 aatacgaaag ttgctaaagc tcgaaacaag caaaattatg atcgaaaatc agtgactgtg
    18841 gaacactatt taaatgtttt agcggctgaa gagaatatta atctgtcgaa agctttgaat
    18901 gatttgttga gagaaaagtt gatttgatgt ctctcagatg atcatattaa gcaaaaacag
    18961 cttgttttag gacgtatgga tttaagaaag acaaattatc aaagaatata ttaaaagctc
    19021 tcagaagcct tctgagagct tttaaattgc tatgtattgt actacatctg ctcaaattga
    19081 ttttcttttc atgcttacca tgtatctagt tttccatcaa gtaattttta gatatgtatt
    19141 gagtaataaa tacccgtggt gctagttaat tttaatatcc taaagaatat ctcaaagttc
    19201 cttcaaaacg tcgttgtgct cgacttaata gaacactgta agccagtaat atgctttcaa
    19261 atctactctc tagcccttta acagaacgtg agttgaaatt ttgacaacct aatttttcta
    19321 aggaagaaaa aacagtccca actgtttttc tttgttttcc aagtaagctg tggtctagtt
    19381 tttctgattt atccatgttt ttacgtggcg gaa
//
LOCUS       DBBGSP010000054        19334 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000054 DBBGSP010000000
VERSION     DBBGSP010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.054"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..1350
                     /locus_tag="ACIZE9_002276"
     CDS             <1..1350
                     /locus_tag="ACIZE9_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HGC6094106.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2827
                     /locus_tag="ACIZE9_002277"
     CDS             1484..2827
                     /locus_tag="ACIZE9_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC6094107.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2939..4294
                     /locus_tag="ACIZE9_002278"
     CDS             2939..4294
                     /locus_tag="ACIZE9_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC6094108.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTISSTESSTTSSSTSEITSS
                     KVTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPILSGNEEIHFDKNESVE
                     NFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQAPNYNLFGIKGTYNGNF
                     VIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGISGNKDFYAGALKANSK
                     TYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSI
                     TSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSWGNYVVIQHEDGSTALY
                     AHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDSSLSQSMLVDPKTLLFG
                     D"
     gene            4643..5275
                     /locus_tag="ACIZE9_002279"
     CDS             4643..5275
                     /locus_tag="ACIZE9_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HGC6094109.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            5863..7302
                     /locus_tag="ACIZE9_002280"
     CDS             5863..7302
                     /locus_tag="ACIZE9_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6094110.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7597..7815
                     /locus_tag="ACIZE9_002281"
                     /pseudo
     CDS             7597..7815
                     /locus_tag="ACIZE9_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            8064..8279
                     /locus_tag="ACIZE9_002282"
     CDS             8064..8279
                     /locus_tag="ACIZE9_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094111.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8496..8752)
                     /locus_tag="ACIZE9_002283"
                     /pseudo
     CDS             complement(8496..8752)
                     /locus_tag="ACIZE9_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8939..9850)
                     /locus_tag="ACIZE9_002284"
     CDS             complement(8939..9850)
                     /locus_tag="ACIZE9_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGC6094112.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(9869..10873)
                     /locus_tag="ACIZE9_002285"
     CDS             complement(9869..10873)
                     /locus_tag="ACIZE9_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HGC6094113.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(10870..12993)
                     /locus_tag="ACIZE9_002286"
     CDS             complement(10870..12993)
                     /locus_tag="ACIZE9_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HGC6094114.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(12998..15445)
                     /locus_tag="ACIZE9_002287"
     CDS             complement(12998..15445)
                     /locus_tag="ACIZE9_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6094115.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(15432..15821)
                     /locus_tag="ACIZE9_002288"
     CDS             complement(15432..15821)
                     /locus_tag="ACIZE9_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGC6094116.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(15881..16384)
                     /locus_tag="ACIZE9_002289"
     CDS             complement(15881..16384)
                     /locus_tag="ACIZE9_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HGC6094117.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(16397..16621)
                     /locus_tag="ACIZE9_002290"
     CDS             complement(16397..16621)
                     /locus_tag="ACIZE9_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094118.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(16725..18635)
                     /gene="ltrA"
                     /locus_tag="ACIZE9_002291"
     CDS             complement(16725..18635)
                     /gene="ltrA"
                     /locus_tag="ACIZE9_002291"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGC6094119.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         6043 a         3647 c         3483 g         6161 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttaaaggca gtaacaggat taaacattga
     2821 aacataatcg ttactaaatg aaatcaagaa atatactgta ttactcaatt cattgaaaat
     2881 atttatcata atttttaata gaaaacacta ttaaagagaa aaaagagagg taaatcaaat
     2941 gaaaaaatct ttaaaacttg catcagcagt tatattaatg tcccaactcc ttatagcaac
     3001 acctttccat gtgttggcaa gcgaaaattc aacatacaaa attgcaaaag aaagaaccga
     3061 gacgactgaa atgagtaatt ccgatgtaac agcagagagt agtgaacttt tgacaacttc
     3121 atcaagtgaa agtagtacga cttcaaatgc cgagtcttca acaacttcgt caagtgaaag
     3181 tagtacgatt tcaagtaccg aatcttcaac aacttcaagt agtacaagtg aaataacttc
     3241 ttcgaaagtg acaaaaccaa accatataga atcttcaaaa aaggaagcgc caaaaacgga
     3301 aggacaaaca aaaacttttt cgacaccaca gcaaatagaa tcaacagaat ctttccaatc
     3361 acaaccaata ctatctggta atgaagaaat tcattttgac aaaaatgaat ctgtagaaaa
     3421 ttttattatg aaaattggtg agtctgcgag aaaaattggt cagaaatatg atttatatgc
     3481 ttctgttatg attgcacaag cgatcttaga atctgccagt ggtcaaagcc agttagctca
     3541 ggcaccgaat tacaatttat ttgggataaa aggaacttat aatggaaact ttgtcattat
     3601 ggtaacaaac gaagatttgg gtaatggaac gctttatacg acccaatcaa aatttagagt
     3661 gtatgaaaac tatgaggaaa gctttgaaga ttatgccaaa ttattaacta agggaattag
     3721 tggaaataaa gatttttatg caggagcatt aaaagctaat agtaaaacat atcgagaagc
     3781 aactaaattc cttacaggac ggtatgcaac agatacacaa tactatttga agctaaatga
     3841 attaattaaa acctacgatt taaccaacta tgataaagaa gttaaaggtc cacaaatgag
     3901 taagactgga taccaagtgc ctattcataa ttattcaata accagtttgt ttggaaatcg
     3961 tggaaatgaa tttcaccgag gacttgatat ggcagctaca cagggtgagc cgattcatgc
     4021 agttaaagct ggtaaggttg ttaaagcaga gtttcactac tcttggggaa attacgtggt
     4081 gatacaacac gaagatggat caaccgcgtt atatgctcac cagcaacaat acctagtaaa
     4141 aactggagat aatgttttgc aaggacaaat aattggctat gtaggaagta ctgggaatag
     4201 tactggccca caccttcatt tggaaatttg caaagatagt agtctttctc agagcatgtt
     4261 agttgatccg aaaaccttat tattcggaga ctaaaaaagg taatcaatct gacaaagtaa
     4321 caagaaaatg gttggattct tagacctttg atcaggatat tgagactgga attgatatct
     4381 cgattacgat gggtttgaca aataaaacaa gtccattatc gaatatcgag tgtattattg
     4441 ccgtctttat gctcatattt tgagcaggtt tcactagatg aaaacaattt atctatcttg
     4501 aggatttcgt gtacgtatcg ttcagtcttg tattgtaaat tagtcataaa atcagactaa
     4561 gaaaaattgg aaatattttt ttctgattta ttaaaagtta attgaaatta tatggtactt
     4621 ctttcttggg agggtaggtg cagtgaagga aagatatggt caccttactg ttgttgagga
     4681 gattactcat aatggatata aaaaatatcg ttgcctatgt gactgtggga atgaaacgat
     4741 tgtatatcga tcaaacttac tatcaggtag aaccaaaagt tgtggatgtg gaaattataa
     4801 aaataggcat aaatataaaa atttgacaaa taaaactttt ggtaagttag ttgcaatcaa
     4861 gccaactaaa ctgcgaagtg aaggaactgt tgtttgggaa tgtcaatgtc tgtgtgggag
     4921 aaaaaagtta gtatcggcaa agcgacttct aaaaggtgat gtaaaaagct gtggatgttt
     4981 gaaatcaaaa aagcatcaca ttgaaaataa aaaattcgga ttacttactg caaagtatcc
     5041 tttggacaat aactgttcat ggaaaacaaa atgggtttgt cattgtgagt gtggcagtat
     5101 gtgtgagata agttatagta acttattttt tggacatact caaagttgtg gatgtttaaa
     5161 aaggcaagaa acaaggacat gtgttgaagg gacagtaata gagtgtctaa cgtcaaaatt
     5221 accgaaaaat aatacaagtg gtgttaaggg agtttatcgt tctaaagaga aatagattgc
     5281 gtatataact ttaaaaaaaa agaggtacta tttaggatcg tatgattcta ttaagagtgc
     5341 agctcaagct agaaaagatg ctgaaaataa attgtttcaa cctttgattg acaaatatcg
     5401 aggtaatcat taattattgt ggataataat taacagtgat atataaacat ctataatata
     5461 ttattcatac tattgatatt tagtataatc ctatggaatt gaatatcata gcaatgtatt
     5521 tgaaaagcaa attggaaaac aaataggtgc aacaccataa atatgaaaaa attgggaaaa
     5581 agtagaatgg aaatttgctt acgtctcacg agatagctca cactattaat ctgaagaaca
     5641 atgaagtcga cttttagaaa ttgctagaag aaagtaaagc gaattatcac tagttactat
     5701 agagtaagtt caaataaagc atctccaact tacatggtta catgaggata tcaaatcgaa
     5761 attactcaag cttcctatgg ctagagtcgc gagaagttgt tgggcagtag acataggtta
     5821 tattgttctt agctacacga tcattagaaa ggaaatccta ttatgtatag ttatcaagaa
     5881 gatgcaaaag tccaaaaaaa tcgctggtgg attttgattg ctatatctat gtttaccttc
     5941 atgtccacat tggatggcag tattgtcaat attgcactac ctaccatctc agatgatatg
     6001 ggcataccaa tgaatcaagc ggaatgggta gtgtccgttt atctgatgat tgtctgttct
     6061 tgtttgttgc tgtttggtaa aattggcgat agccgtggga aaatcaaagt atttcggatt
     6121 ggtacgctga tctttgtctt gggatcgctg ttgtgtgggt tcaatcattc gctaggtatt
     6181 ttattgttcg cacgggtggt acaagccatt ggtgctagta tgactatggc tacaaatgcc
     6241 ggaatcatca cggaagtctt tcccatacat gaacgtggtc gggcattggg agcaataggt
     6301 gcgtttgttt cattaggctc gattgctgga ccaggtcttg gcggcttgat tttgtcccaa
     6361 ttttcttggg cgtacatttt ttggatcaat gtaccggtgg gaatcgtaac gatgttgatt
     6421 gctgaaaaat tcttaccaaa agatatcacc atgagcggcc atacaatcga tggagggggc
     6481 tttgctgcca ttgcggctac gattatcagc ttttttggag caatcttttt ggggcaagaa
     6541 agtggctttt tccatccagt cccccttgta ctgttcgtaa tttcagtgat tgcctttgtc
     6601 agctttttaa aagttgaaaa gaaagcagcc tctccattga tttctttcgg tatttttaag
     6661 aacaagattt ttaccatgag cttgattaca gccttgttga ttttttcttc caacttcttt
     6721 gtcaatgtag tgattccttt ttatctgcaa aatgctcgcg ggttgagtcc tagctatgct
     6781 gggctgttga tgatggtctt tcctttgatg atggtcgtcg gggcgccttt aagcggctac
     6841 ctgaccgacc gggttggccc ggagattttg gtattagtag gcttgggctt attgtcggta
     6901 acccaggtca tgtatatgtt tttgtcagtg gactctcctt tgtggctata cattgtcgct
     6961 actgccatca tgggtgccgg caatgccttg ttccagtccc ccaataatac gatggttatg
     7021 agctcggtca ctatcgaaaa cttgggactg gcaggctcga tgaattcctt tgcccgaaat
     7081 ttggggatgg tcagcgggat ttcgctttct acgacggtct tatatcaagc gatgtctgct
     7141 aagatgggcc agcaagtaac taactatatc gcaaatcggc cggatgtctt tttatatgga
     7201 atgaagatta cctttttagg cagctttgtt ttgtgttttg ttgccttttt cctgactatc
     7261 tggcgtatca aaaaacaagg aggtattcag aaaaatgtct gaaaaaacca ctgttgaaga
     7321 atttttggag gcctgcgtat gggtgagtgg gatttccatg gatgatggaa gatgaagtga
     7381 acttctaaaa gccgaaaaac tcaagtatta tcttcaaaat actagtgctc aatgagatgc
     7441 ttgatttgat cacaagaaga ctgcgaaagc cgctggcaac cgcaagctag gtatcccacc
     7501 gatggactac gttttagagg ctactggtta tgaatacgga gccaacgctc tcatctgcat
     7561 aagaatacat cacccagatt atgtaaagat tttcgatact tctgtcaaaa aatcattaag
     7621 atagataaat gatttccgtc tagtcaaatt ggttcagaat gtagacacac agatggtaag
     7681 aagtcactca caattcgaga atggacttgt cctatttgcc gtatacatca taatcgaaac
     7741 gtcaacgata gtatcaatat tttgaccaag ggctatgaat acaagcattg ccttagaaaa
     7801 catcaagaac cttaggaaca acggggatag cttggttaat aagagatacc gctgtttagg
     7861 cttgcaagta tactctttta tcaagaattc cgtggcttta gtcatgagag gcttaatact
     7921 atgaaaattt tctttagcat ttttgattta ggttcctttt ctaattataa taagatgacc
     7981 actacagtaa cctactgaaa tatataaaca gccactgtag taccattttc aaagtagtct
     8041 atgagaggag aatcttcatt cttatgaacg ctggaattgc ggatatgaat ttaataaaaa
     8101 aaacccttaa tgattttact tccaattcaa tatcaaaagg tactggtatc aatttaagca
     8161 caataaaaaa gctgaaaagt ggtgaaagat cagtggaaaa gctgaatctt ttagatgcta
     8221 taaaaataac ggaatttgct atgaaaaatg gaaaagctga gattgaaata tggagataat
     8281 tatcgtctag tgaattactt gccacttagc tgaatttaac gatccttggt gcttgaaggg
     8341 ggagattctt gggaatagag catacttgca agcctatgtc tttactaaca acgatatctc
     8401 ttattaacca agctatcccc gtagttctaa ggcttttact tttatctaag caataatcgt
     8461 attcaaagga aatttttgac ccttagaaag tctcatttta tcagacgtga gcttaggcat
     8521 tgctgaattt tgttaattcg gttttaggtt gtgctttgag cataatatga aagtattctt
     8581 tatcacgatt tcattcatct aaggtaatgt gatgtgattc tgaaattctt tcaaaggcag
     8641 tttttgcata agctgacatt acatcatcaa tgacatgttt acaatgtttc actactaaaa
     8701 taagggggta accaagaaga aaaactgaat gattatttgt atctaattcc atggtatatc
     8761 aaccatttcc tatatagact gattatgaca tggattaaaa taaaaaggca ctatgtctta
     8821 attgtcggtt ttcgagttac cgaatggcat tcatcaccca cctatagagg atgggcgact
     8881 tctgcctgaa ataagttaca ctacttataa cttctaataa aattagattg agtcattatt
     8941 atttaacatc aacgattttc cagtttccat ttttttgtaa tactaatttg tactgaaagt
     9001 agctagtggt ttttgataca ttatcaaggt attttatctt tgtactcact agaaaatttt
     9061 ttccgttttg tagataaact ggattctcta actccgaaaa ctttaagtca atattgattg
     9121 gtcgcatcgc accattttca acataatact ccaattcttt ttcagaagct gatggataaa
     9181 gtttaaaaaa tgtttctaaa aaatcggtga tttcttccgt tgttttggca tcaatttctg
     9241 aatcgttttc tacttgtttt gcttcatatt ttgccttgtc tggctttcca atcattgttg
     9301 gcaaactagt tactaaatga ttcctgtttt catcttcaaa gattgtcact cgatatgcag
     9361 aagaaattga ttgcgtcttt tttccctctg taatatgttg ctccactaaa aatgaaacga
     9421 caaattcttc cgagtgtttt tcaacatcta gaatttttac agattgaact tcggaactcg
     9481 tgggaatatc tgctcgaacc atatcttgga ttaaagcgag accgttttct gtaaggtact
     9541 gttcgagatt actcattctc ttttcaattg cttctttgtt atttttccat gaaaaatatt
     9601 ctttcgcaaa atcctctgta aaactttcaa cgccagaagt attcactacc ttctctttta
     9661 taaccacttt ttcatgagtt gtatgttgat caatggcggt gaaattttta taaacgccaa
     9721 aagcaagact acaagacaat aaaagccaaa gggcaagcac catttttcga tgcttaccca
     9781 cggatacaac tcgttctttt ttcttttttg ggctcttttc cttttgattc cgttcaattt
     9841 ttatcttcat tctttttcct cttttctctt atttgtatcg gccagctccg ataagatgct
     9901 gccgccaata gttttccgtt agattcgtcc accccactgg atctcctgca tgaaacatgc
     9961 gattctcccc tgcgtaaatg cccacatggg tcacataagt accggcatca taggttgaat
    10021 gaaagaaaac taaatcacct ggtttggcat cttttagatc aatatgagtc atggcatcat
    10081 attgatcctg agccacccga ggaagtttca ggtcaacttt ggcataacac cattgggtca
    10141 agccactaca atcaaacccc gtttctggac ttgagccacc aaacacatag gccgttcctt
    10201 catacttaaa tgcctcatca aaaatttctt ggactatttt gtcatcaaac tgagttgtag
    10261 ttaggtattg cttcactaat aaacagtaaa acatattgcc ataattatac cgccacccac
    10321 cattttcctt aatcgcgatt gggttggggt aatcgacttt ttgaccacct gatttttcct
    10381 ttgaaaaaga ttcagctaaa gcaaaactat gcttcttccc gtttttcccg acatgatcta
    10441 gatacccgcc accatagtta taggcctgaa taatactatc ttgatcacac cctagttctt
    10501 tggaacgctt aaccaaagac gcaaaataga gacagccttg tttgatggat gcctcggtac
    10561 ttaatgaatt aggtggtaat ccggctgact cagaactttg cataacgtct tccattgtgc
    10621 caccagattc cacttgaata atcgccaaaa gaattggaat atactctgtt atatccgatt
    10681 ctttggcata cttttccacc attgcacggt gtttcaatac ttcttctgag acactagttc
    10741 cgccaggaga agtgccagaa ctaccatttc cctcactgtc ttcaccaaac aacaaaccca
    10801 cacacatcaa aatacccata aaagagatgg tcagaaaagt taatgaaata acacccactt
    10861 tcttcaagtt cattttttct cacctgacct tgattttgga cgatggttca ttcttttttg
    10921 tactttttga ttggtctgct ttggcagagt ggacctctgt ttcacttgtt ggaaagaatt
    10981 tttcttactt gctgattggc ttttcccttt tgaaatgatt tcttgactag ttagttttcg
    11041 tttgatttcg ggattcagat ttgctctcac aatccgcttt ggtgcttctt ttttcagcat
    11101 catatctttc tgaggttgag ctgctttatc tattggaata ttcgcccttc tttttccctg
    11161 acgatttgtt gcttcactca gtatcttgcg tttttcgtcc attttcgcat ttcttcgttg
    11221 tcgttgtttt tctcgcaaat ccactcgatc cgctttttct tggaacagtc cgcgcttgaa
    11281 ttcttctggt gcttttttcg acttttcgat tcctttatgg agattgtatt tcaaattcgt
    11341 tggcgtattc cttacctgat cctttacttg tttagtctta tctttcacca aagcttgggt
    11401 atccaaaact ttgccgattt ttctcccagc caaattcatt cgggattgtt tcttattatt
    11461 tgaaactgga ttctccttag ttaagtcaga tagtatttcg tgatcgttcg gtaatcgtga
    11521 attctttcgt agagaagaac cggatggctt aaatttggat tttgattgtt cctttgccaa
    11581 cttatttccg actgctgcac caccaccaaa agccaaagct cgtcccacat ttcgattgag
    11641 ttgccgcaat tttcgattca ttaacatttg cggttttcgc atgacgcgtc ttcccattga
    11701 ctggctatca ttactctgga ggttgaacat actcataatg tcgcccaatt tgaaatagat
    11761 accggcaaag gtcacaattt gcagaaaagc aaccatgaaa aatggatagg ttgccgaaat
    11821 attgaaaaac atcgtggaga tgctaaatgc agtcgtaatc accaaagtaa cacccgctcg
    11881 catcataatc gtattgaata aacgaataat cgccttcttt cctaaacttt cataagtcgg
    11941 caacatggac aataagaaac taattggcag aaacatcgca aagataatga agagaatttg
    12001 cgagaacaac ataatccctg ttagaagaaa aacaaagaag gaaatgccaa tattgaacaa
    12061 taccaaaaag accacggtcc ctaaacggtt catggtcttg gtaatactga gattcgcatt
    12121 gtcattgtct tcaatctctg ccttgaccgc ttcttcccga tctttgcctt tgttttcatc
    12181 tggactcaca gatagaatct tgttgacccg gtcttcacca atttcttcta tgttggaatc
    12241 atcaaattgc agtagtaacc aaggttgttg gacttgaatc gaaaacaaac tatcccgaat
    12301 caaatccaca ctatcttttc cttggctttc tgaattgggt acaacgatct cggttccaag
    12361 ggtaagggcc gcttcactaa catctgagct aaagtcattg atttttgtga tataggtagg
    12421 cgcataagca atgaacgaac ccgatagtag aaaaatcatc acaaaattaa tcacggctcg
    12481 aactgctttc gtggtttctc gttttaataa tccggtatac gccacataca cccccagagc
    12541 taaaatcatc aataatagaa acccaaaata aaatccggag gtctggagtc cattttcagt
    12601 aataccagcc aatgtttgga tattctttcc aatactttca gccgtatccg aaatgaaatc
    12661 taatttgtaa gcctcttgaa ccacataacc cgtggcgttc gacaaataca aactcaccgt
    12721 ccaaatgaaa ttagtaatgg cataaagacc atacatcacg cttttcccta agccatcacc
    12781 ccaattccaa ggcaaccaat cccaagagct atccacaaag aaatctagtt gatagttgtt
    12841 cagtgaatat ttggaatata gatttcctgc ttcaactgta tcatcaacta gccctgtcgc
    12901 ctcggctacc gtaccaacta aactcaatag aactatcaga gtgagtatgc taataaaaac
    12961 gattcccaca atccgaaaaa gtttcttttt catcccctca ctccattctc tcttgaacag
    13021 gtggacgggt atcaaaggca tggaagagtt cttcaaagac tggatgtacc tgaaccacgc
    13081 ctacccgacc atacaaatcc tgcatcaagc attggccatt ttccaaatct cgtaggcgtt
    13141 tttgattgct ttcatcttct cgatccaagc caaagaattc caaggttttc ttgatttcat
    13201 gaatatcggt actgcgaaac gcaaacttca acccgatatt attcttcaag cgttcatcca
    13261 gtaaatcatc actattttgc gtgacaaagt aaaccccggc attcatagcc cgcccagcac
    13321 gaacgagctt attcgataat gttttccctt gcgctacttg aagaaaactc cacgcctcat
    13381 ctaagtctac aattttgaag atttctcgat tactatggat aaagtccaag gcaaaagtgg
    13441 aaatgacgat tagcatggaa acactaagca attccatggt ggtatattct tcaaaagtgg
    13501 tttctgcatc tggtaaaacc aaatccgcta cttgaatgat atttaactgc ctatctaaac
    13561 taatcgactg ggtaatcgaa ccatctgaga aaagcaaatg ggcaaaatca taatcggtaa
    13621 aggactcgat gtgatccgcg atattttccg caactggtga gccttctttt cgaagctcat
    13681 taattacttg taataatccc cgttgattgc tttgggtaac cgtccgaatg gccttacgca
    13741 acactggaaa cttctcccca tctcgactag aaattcctgt taaaaaggtc agaatatcaa
    13801 ttgctagact ttcagaatcc ttctttttct ccataatcac ataaggatca agtaatcctt
    13861 gattttttgg cttactagtt aagttgagaa tattgatttc atccgcaatt tctggcaagg
    13921 tttctttcca gccaccccgt tccccttttg gatcgacaat cacagcttgt ccaccaaaaa
    13981 ggacggcgta ataaactaag agattgttac taaaggactt tccgccaccg agtgaaccga
    14041 ggaatgccgc tgctagcgca ttggtaactg aatccttgac cccttgtgag gccaatgccg
    14101 gtttcaggta aacattgcgc cccgtatcta cgttataacc aaagtaaatg ccttccaact
    14161 cccctaacat ctgagtggcg ccaaaaccaa gtccggcgag aaaatcagac gtaacatact
    14221 ggatataatc attcatgtat cgcttactag aaggtaagaa ttcttcatgt agccccatca
    14281 tatcgccaaa aggccggact agttttacat tggtatcatc ataaaaatct agcacttcat
    14341 cacaccggcg ctttagttca tctactgatt cggcacttac tcgaaccaca tagctcagtt
    14401 tgtacatgga ttctttggac tgatccaagg tagtttccaa ttcatctacg gaatccaatg
    14461 catctaagac attggaattt gtttcattgt cagattgata ggcatggttg tccaagtctt
    14521 ttaattcctt tttcttattg cgaacggtag caagtgcctt tttgttcgtc acaatctcca
    14581 cattcatact agtgtcaatt gggaatgtaa attgttgttg ctggtaatag aaaagttctg
    14641 aggagggaaa ctccatttcc cccacaattg tattaattgt taagtacgct acatatgatt
    14701 catgattctc atgttccatg cataagtacc ggggcttttc ttcaatcaaa caacgactgg
    14761 gacgtaataa gtcgtaacgt ttcaccaaag tttccgactt cagctttttc tttggtagct
    14821 gaaattcata ttcttcaaat ggtgtaccct tttcgccata gatatgttca atcaaataca
    14881 tcagatcact cggtgtgact cgtctgactt taaatcttcg agccaattta ctttccatta
    14941 gtttttcaag cttggtatat cggcgaattt cttcattgga taaggaaaca aaatcgccca
    15001 tcaaatgatg attcactcca tagacaaatt cttgaaagcc ggagaagaaa gatttcttga
    15061 gattctttag attgacctct tcatctgtcg caatcagttt gaagccaata aaaaagcgat
    15121 aatcaatctg actatcgcca atcatggata ctaatgcctc tgtctgtaaa tcaattcgtt
    15181 gtttcgctac ttctgttaat cgcccggtaa tttccttttt tgatcgttct tgcgtggcac
    15241 gaatactact ttctgtggca atttgtaagg catgaatctt gccttcacga ttttgcgcaa
    15301 tcaattgacg aaagttatcg tggacttgat atttctgttc aggtgacaaa aaggagtaat
    15361 tgtaaggtat taactcatag taggcaaaac attctccctc ttgattaaag acaagattat
    15421 tttcaatata cttaatcggg tacatagttc acactcctta ccagagtaat gggttcgtcc
    15481 catcgtttct tctgttcttt gactttcttt cctgcgaaag tgaccttaaa tcgtaagtga
    15541 tagctaataa aagatcgtaa aaatcccaat ggtttcttac cgtcaaacgt tttttgcgac
    15601 atgaaccaag taactgccac cggtatacct aagtatttta aaaaggcccc ctctatcata
    15661 gatagtggag gcacatgggc aaatacgatg acaaacagca aggataaaac aaaccaagcc
    15721 atctggttaa aagtcacagg aaaaggcagt tgaaagtcat taattgcata aatgaccttt
    15781 tcaactgccc aaatactggt gtagcttttt attttcttca tcaaatcatt cctttaaaaa
    15841 gaaggatagt ttagaaatca actacccttc aataattttg ttaatatgga tactcaaaaa
    15901 cacctcgact cgttaccaaa taattgcctc caatctccaa gtctctacca cacgcatcaa
    15961 aatcaatata cgtcttcaag tgttctggta cttctccaaa atcaccagct tctacaatca
    16021 agaaatatgc tacatcactc atatcatcgc aatctggata atagataata tcatccacat
    16081 gctctaccat ctcctcaaaa gaattgaaga aagcatgttg aatctcagaa gcaacttcac
    16141 caactggcgt tccttcaagt tcctccgcta agccacacaa ccgattaatt tcctcaattg
    16201 gcgtatactc atcaatctca aagggaagtt cataatcatg aattgcatat tcctcgtatt
    16261 cgtcatttaa cccaattcgt tctttcactt catcaaaatc gacaggtggg gtaaaccacg
    16321 cccccaccaa ttcaccttcg ttatatttcc cgaggttcgc aatataaaca cgcatctgtt
    16381 ccatcgtgct tcccccttac gcaccgacaa ttcggttaaa caaactgagt aagacatcct
    16441 tcaccccaga agcattaaag accaatccga ccgcaatcaa agcaatcacc aaaaagccaa
    16501 tcagtttgga aaactcccgc ttaaatccta aaaacaaacc aatgaccaca attgccagta
    16561 agactaagga ttgggcattg gttaaaaacc attgatatat ggataggtaa gttcctgata
    16621 ttataaatat ctcaaacttt tccccccatt cacacggagc gtgcgacttt caccgcactc
    16681 cgcgttccat cgtgtttata ttgaaaagta tttatgtagt agacctatat caagtttaat
    16741 tcttgattgc cagctaatac tctatattta tttagtctta tgagctggac tttatttagc
    16801 ttcaatagag ctatatattt ttgtattgtt tcttctgttt tagcgtgtat tagacggtgt
    16861 accgcctctt ttaccaaaat aagattttta taatcgtcat ttccaccagc tccagttggt
    16921 acaatatgat gacaatgtat ttcattagct tgttgaaatt cttccagagt tatagcacat
    16981 tttccatgtt gagcagaaaa tagcgaaatt cgattgtctg cgtattctat tgtgcgattt
    17041 tccaaagata atttcattaa ctggtacatc agtaatttat caacacttag attggtgtgg
    17101 ataaattttc ttccctctag agtgtagcaa ttcgctaaat acacctttgc cattggtttt
    17161 ctgtgttgga tatatccaac agggaaaata ggttcgccct cgccagcaac ataccgaagc
    17221 attttagatt taccatatct tgttgcctcc tttgtcgtaa gttgtctgcc tgtttttctc
    17281 aatctgcccc ttttgtttgt acctaatctg ttagtgaaga tagccattac agctctattc
    17341 agtttcatac aatccagatt tacattcgtt gcaatctgat aataattttg catacctaat
    17401 accattgaat tataaagtct tgtttcttct aattccgttt tcccttttga gggagaagca
    17461 attttctttg cctgtgatac cagcttgtct ttttggtttt tgaattgttt atcacttata
    17521 tgtgatttaa caactaactt ctttcttctc ggtatcattt taatcttgaa accaagaaag
    17581 tcggagtatc tttttctaac atttacaatt cttgtttttt cttgtgatac ttccaatttt
    17641 aatcgttgtt caatccattg agtgattgct attttggctt tttcagcact ttccttgtag
    17701 cggcagaaaa ctctaaaatc atctgcataa cgaaccatat acatttcctt taactttgtt
    17761 ttcttcattt ctttgtaagc gttgctttta catgggctac cgcttttatt gatatgaacc
    17821 acatagtttt ttgtaacagg attttcctgc cattggcttt ctacccaatg gtctaactca
    17881 ttaagaacaa tgtttgctag tagtggggat attattcccc cttgcggagt tcctttctct
    17941 ggatatgtta ttgtaccgtt agtcattttg attggagctt ttaatatcct ttttaaaatg
    18001 aatatcaagt gcttgtcccg tattcccata gcccatatct gttttatcag cttggaatgg
    18061 ttcacgttgt caaagaaacc cttaatatca aattcaatca cataatgtag ctggctgatt
    18121 tgtaggcggt tataggttgc ttttattgca ttttcaactg acctattagg tctaaaacca
    18181 tagctgtttt cactaaattt agcttcgcag attggttcta atacttgttt tatacattgt
    18241 tgtataagcc tgtcccacat acaaggaata cctagaggtc tggttttacc atttggtttt
    18301 ggtatttctt ttcgcctcac tggcttaggt cgatacccat gtggactgcc tgcaacaatg
    18361 tatcttactt ttttgacaac tgtttctgct ggcaatttgc caatatcttt aattattgta
    18421 ccgtctgttc ctgctgtttt actgcctgca tttgctttga tatttcgata tgccagtaat
    18481 atattttctc tcgataggat aatatccata agatgagtga aaatatctcc attcttactt
    18541 ttggcatata aatcatcaaa ggtgttttgc atttcgtaat attcagcgtg tcttaaatct
    18601 tctacacaca atgtttcatt tttattttta ggcataaggc ttcactcctt tacttgaaat
    18661 tgagtgagct tttttatctt actcgtaatc cttattgaaa caacataata cttttctaat
    18721 atatacacga cttgagggca ttcctccatt ctcattacaa gaatttctta ggttcgccct
    18781 ctgcttttca gcattagttc aactgcttat tgttcttcgt cagtttattc tcttgatgag
    18841 aacccaatac ctttcctcgt tccgataatc ttatctatac atatatatcc ttaggtcact
    18901 agctataagc ctgctggctt gataccgcct gtaacgttat atggcatttc ataacctata
    18961 ttcttacttt gccacaccag ctacgatttc tcgtaccttt gcatttctac aaagttcaaa
    19021 tttagacccg tacattcgct gtttcgtcag ttccttatag aacattctaa ccatagatat
    19081 tttatagacc cccgacctgt tggatacgct acccacctct ggatagtttt cgatagaaga
    19141 tatatgttca tcaactatta cggtatcttt cagccgtctt taccgagctt caaacattct
    19201 gagtttcctc atacaatgct tgtcggaggc tcagggcagg cgtttcagag cgttacttca
    19261 tcattccacc tgtcagatta tcagttctcc taataaccaa actttttcgt tcttttatta
    19321 gtgccttagc tttt
//
LOCUS       DBBGSP010000055        18504 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000055 DBBGSP010000000
VERSION     DBBGSP010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.055"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            99..746
                     /locus_tag="ACIZE9_002292"
     CDS             99..746
                     /locus_tag="ACIZE9_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGC6094120.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKLLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    875..1091
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1139..3784
                     /locus_tag="ACIZE9_002293"
     CDS             1139..3784
                     /locus_tag="ACIZE9_002293"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGC6094121.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4094..5407
                     /locus_tag="ACIZE9_002294"
     CDS             4094..5407
                     /locus_tag="ACIZE9_002294"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGC6094122.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5397..6050
                     /locus_tag="ACIZE9_002295"
     CDS             5397..6050
                     /locus_tag="ACIZE9_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6094123.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6105..6797
                     /gene="radC"
                     /locus_tag="ACIZE9_002296"
     CDS             6105..6797
                     /gene="radC"
                     /locus_tag="ACIZE9_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGC6094124.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6947..7147
                     /locus_tag="ACIZE9_002297"
     CDS             6947..7147
                     /locus_tag="ACIZE9_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC6094125.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7401..9080)
                     /locus_tag="ACIZE9_002298"
     CDS             complement(7401..9080)
                     /locus_tag="ACIZE9_002298"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGC6094126.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9082..9294)
                     /locus_tag="ACIZE9_002299"
     CDS             complement(9082..9294)
                     /locus_tag="ACIZE9_002299"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HGC6094127.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9687..11417
                     /gene="efrA"
                     /locus_tag="ACIZE9_002300"
     CDS             9687..11417
                     /gene="efrA"
                     /locus_tag="ACIZE9_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HGC6094128.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11414..13174
                     /gene="efrB"
                     /locus_tag="ACIZE9_002301"
     CDS             11414..13174
                     /gene="efrB"
                     /locus_tag="ACIZE9_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HGC6094129.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13269..13466
                     /locus_tag="ACIZE9_002302"
     CDS             13269..13466
                     /locus_tag="ACIZE9_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094130.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13619..14104
                     /locus_tag="ACIZE9_002303"
     CDS             13619..14104
                     /locus_tag="ACIZE9_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HGC6094131.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="ACIZE9_002304"
     CDS             complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="ACIZE9_002304"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HGC6094132.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            14981..15508
                     /locus_tag="ACIZE9_002305"
     CDS             14981..15508
                     /locus_tag="ACIZE9_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094133.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15599..16336
                     /locus_tag="ACIZE9_002306"
     CDS             15599..16336
                     /locus_tag="ACIZE9_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HGC6094134.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16340..17257
                     /gene="miaA"
                     /locus_tag="ACIZE9_002307"
     CDS             16340..17257
                     /gene="miaA"
                     /locus_tag="ACIZE9_002307"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGC6094135.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17259..18488
                     /gene="hflX"
                     /locus_tag="ACIZE9_002308"
     CDS             17259..18488
                     /gene="hflX"
                     /locus_tag="ACIZE9_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGC6094136.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5983 a         3200 c         4022 g         5299 t
ORIGIN      
        1 atttgtctca cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt
       61 acactaaata tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac
      121 tgccaaaagc aactgcgaaa agattacctt tatatttacg ctacttgaag ttgctggatg
      181 actcaggtat aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg
      241 caacgatccg cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg
      301 atgtcccttt tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa
      361 tcgcattagt aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa
      421 atgaaaatct aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa
      481 ttgatggaga aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg
      541 tgacagtagc aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg
      601 tcaaaggaaa tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt
      661 atgtcaatgt tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg
      721 agaattactc agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa
      781 ctcgtcgtaa ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac
      841 ttgttgacta aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa
      901 ctggcacatt cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt
      961 gaaggtagct tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta
     1021 actcacttga gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat
     1081 acgtcctaga atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat
     1141 gacggaagaa aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta
     1201 tcagcattgg ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta
     1261 ttcaatcgta atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga
     1321 tacgaccttg caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg
     1381 gctgcctggt atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag
     1441 agagcaaggg atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga
     1501 atggaaagaa gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt
     1561 agattacagt agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt
     1621 ttttgttacc ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga
     1681 tcctcaagca cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc
     1741 cttttatcat atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac
     1801 ccgtccagaa acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta
     1861 tcaagcgctc atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat
     1921 tgcagatgaa tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca
     1981 tgatccaaac gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga
     2041 tgatgatggt acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc
     2101 tcgtaaagca atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat
     2161 gatccacagt gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac
     2221 tcaatggttt gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga
     2281 tcaagcagtg gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa
     2341 tgtccatgat tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta
     2401 tcacaaagaa acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg
     2461 ggtacaagat cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac
     2521 aatgggctgg ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt
     2581 agtaaccggt tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga
     2641 atttactggc gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca
     2701 agggcggaag atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa
     2761 gtatggagca gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt
     2821 ccgcttcagc tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc
     2881 ttcacgtttc gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg
     2941 agaaaaatca gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt
     3001 aactgagcta tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat
     3061 ctgggatgat ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga
     3121 tgctgtttca aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg
     3181 tttattgcat ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca
     3241 gggaaattct ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac
     3301 agcttctaaa gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc
     3361 agaagtgaat acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa
     3421 aatcgatcaa tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga
     3481 gttgacgata tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg
     3541 tgcagaaatc ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt
     3601 agaaaaagaa ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa
     3661 tgaacgtttt gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa
     3721 agattattta gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca
     3781 ataagaatag aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga
     3841 acatcgttac aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga
     3901 cataaatttt gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg
     3961 tggatcatgt atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt
     4021 ttctctttgt catactttta tttttcttat gtgttctatt tgttataata aaagagaaat
     4081 gggggaattg ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt
     4141 tggttcacgt cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga
     4201 gagaaaagta aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta
     4261 tttgagaagc ctattagaag aggctgggct gacagtaggt acatttactt caccttatat
     4321 cgaaacgttc aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat
     4381 ccagcttgta aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc
     4441 tggtattact gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa
     4501 agtggacgta gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc
     4561 tgtaccaatg ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga
     4621 tacaattgaa gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt
     4681 aacaggaaat attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa
     4741 tgcaccgctt tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat
     4801 gtggggagaa gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc
     4861 gcttttaggg caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta
     4921 ctgtcaattg gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc
     4981 tcgatggcca ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc
     5041 ccataatacg catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata
     5101 tcaaatcaac attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg
     5161 attgcagcaa gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat
     5221 cgaattaagt gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca
     5281 attcggatta gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg
     5341 ttcactttat ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga
     5401 agtataatgc agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt
     5461 acgaagccac acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt
     5521 taaaattctt aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg
     5581 aatttggcaa aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac
     5641 gtttttcgca aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag
     5701 aagaacatca gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt
     5761 tattgaagaa gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc
     5821 aacgagcaaa accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga
     5881 agaaagaaac attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg
     5941 agatcccggt agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa
     6001 cagctggggt tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct
     6061 cttttcgtat cttattttag ataagataga aaggagatgt ttttttggga aaacgattga
     6121 tcaaagaagt acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag
     6181 ctttatcgga tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg
     6241 tgatgtcgat tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg
     6301 ctactttgca tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca
     6361 aagccttgat cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg
     6421 ttcgtaccag ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag
     6481 aacatttggt ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt
     6541 tcatcggttc gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac
     6601 gttattgtgc agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat
     6661 cgcagcagga tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca
     6721 ctgtactgga ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa
     6781 tgatggaaga gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat
     6841 tgtaattttg tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca
     6901 atgttacaat ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac
     6961 agtaaaatgg ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga
     7021 cgtattcgtt cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca
     7081 agcagtgact ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa
     7141 agcttaattt tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa
     7201 gcgagtaaca aaaatacctg ccacaagaga caatttctct tgtggcaggt atttttttgt
     7261 atgaaaaagt aaataaattt aagaggctat gaaagagcca ccttgtatca aggaataaga
     7321 acaaacaaaa atggcttctc atgtttttca tttgttttct cttatattca ggacaaggtg
     7381 ctgatttcat aacctcttat ttattcttca tctggtgtca ttaccattgg caaaatcatt
     7441 ggatgtcttt ctgtacgttc gaataagaaa ggctgaagcg cgccagtcat cgcttctttc
     7501 aatttatatt ctgaacagtc aggtccattc aaacattctc ttaaagcgtg gaataagatt
     7561 cgctgagctt cattgatcat ttctcctgat tctcgcatgt agacaaatcc acgagagaga
     7621 atatctggac cagccaagat ttcttttttc ttgatatcca ctgtcgcgac agctaataca
     7681 agaccttctt ctgaaagcag gtgacggtca cgtaaaacga cattaccaat atcaccgatc
     7741 ccgctaccat cgatatacac atctccagcc acaaaatgcc cagcaggacg cgcagaatcg
     7801 ctagttaacg ctaaaacatc gccattttcc atgatgaagc agttttctgc aggaacacct
     7861 acatcttgtg ctagagaagc atgtactttc aacatgcgga attctccgtg gacaggaata
     7921 aaatattttg gcttcatcaa acgaagcatt aatttttgtt cttcttgtcc accgtgaccg
     7981 gaagtatgga tgttattgat ttttccgtga atcacttctg caccagcttc agacagcaaa
     8041 ttgatcaaat gattgacact tgttgtatta ccaggaatag gtgaacttga aaagatcact
     8101 gtatcgtctg gctggatttg gatttgacgg tgagtaccat tcgcgatgcg gctcaacgcg
     8161 gccatcgctt ctccttgaga acctgtacat aggatcatcg tttcattggc aggcaagcga
     8221 ttgatttcgt gtgcatctac aaatgtgccg tctggaactt tgatatatcc taaacgttga
     8281 ccgttgacga tggcattttc catgcttcgt ccgaaaacag cgattttacg accagttgcc
     8341 acagcggcat ctgctgcttg ctgcaaacgg aagatgttag aagcaaagct ggcaaaaatg
     8401 atacgtcctt cgatttttga aaagatcttc aaaatagaat gcccaatcgt tttttctgat
     8461 ttagtaaatg ttggaatctc agcatttgta ctatcagata aaaggcacaa gactccttct
     8521 tccccgatac gagccatttt atgcaagttt gctggttcgc caacaggagt gaaatcgaat
     8581 ttgaagtctc cagtcgctac gatatttcca gaaggtgttt tcaccacgat ccctaatgca
     8641 tctgggatac tatgggtcgt tctgaaaaag ctgacagaag tctttctaaa acggatgatc
     8701 gtatcttcat tgatctcatg gagctctgca tctcgaagca agccatgctc atctaatttg
     8761 tttgtgatca acgctaatgc gagaggacca gcatagatag gaatatttgc ttgtttcagc
     8821 aagtagggta ttccgccgat gtggtcttcg tgcccgtgag taatcaccaa ggcttttact
     8881 ttgtgtaagt tttgtatgat gtagctgtag tcgggaatga catagtcaat tccaagtaaa
     8941 tcgtcttccg ggaatttgat cccggcatca atcaaaatga tttcatcttg gaattgtacc
     9001 ccatacgtat ttttcccgat ttcacctaat ccaccaatag caaagacgcc tgtctcgtta
     9061 tttttgatgg aaagtttcat attaaaactc cactaatgag aaatcagcat tttctttttc
     9121 gtactctaga tgacttcctt ctagaagttg aacgaattca atattgtatg gggtattttc
     9181 ttccacacgt tggcgagcgt ctacatcgct ttttgcctca atgtaaagag attttgtttc
     9241 ttcccgttta gggttgcgta cttttgtttc ttgataataa actttataga tcattgtttt
     9301 gtctccttta tctgcgtaaa gcagtgattt agctagttga tttttttaga caacacaaaa
     9361 cgaggggaca agccacctgg tttttcatat gctttgacta gaatactgga ttcgagtcaa
     9421 agagacaagc ctcgtttttg cttatctgtt cggatatttt ttcaaccgta ccttctgtat
     9481 aaaaaatata caacaattaa ttgttattct agcataaaac agcaaataag tatagaaatc
     9541 aactagattg aaagaaaaaa tcaatgttta tcatcccgct ataatcataa tgactttttt
     9601 atgagagaag tgttctatta ataggctcgt tgtgctatca tttttagtaa tgaaaatgta
     9661 acaaaagatt aaaaggagat gagaaagtga aactaatgtg gcattatacc atgcgttata
     9721 agaaattctt gtttttcaat ttcatatgcg tatttggttt tattttgatt gaattaggac
     9781 ttcctacgat tttagcacgt atgatcgatg taggaatccg caatgatgat tttgattatg
     9841 tgaagcaaca agggatattt atgatcgtta ttactgtaat cggtattatt ttgaatatct
     9901 tgttaggtta ttttggttcg aggattacga ctaatatcgt agcagatatt cgagatgatt
     9961 tgttcgaaaa gatccaaagt tattcgcatc aggaatacga aaatctaggc gtatcttcat
    10021 tgatcactcg tacaacaaac gatgcttatc agatcatgtt gttcctgcaa aatattttac
    10081 gtatcggttt tatggcacca atgatgttca ttgtcagttt gtacatggtc atgcgtacaa
    10141 gtgtgacact cagtttgtat gtagtaggtg cattaccttt actattattg gcagtcgtag
    10201 cgattgctaa ggtgtctgaa ccgttatcta aaaagcaaca aaaaaactta gataaaatca
    10261 acagtatctt gcgggaaaat ctttcaggat tgcgtgtgat tcgtgcattc gtcaatgaaa
    10321 agtttgaaga aaaacgtttt gctgtagtca atgagaatta tgcttctagt tcaaaaagct
    10381 tattccgttt gatggctgtt gcacaaccgg gtttttattt cttatttaat atcgtaatgg
    10441 tattgatcat ctggagcggg gcagtgcaaa tcgatgcagg cgagcttcgt gtaggagatt
    10501 tgattgcgtt tatcgagtat atattccatg ccttgttctc attcatgtta tttgctagtg
    10561 tgttcatgat gtatccaaga gcagctgttt cagctggacg tatccaagaa gccctagatg
    10621 ccaaaccttc gattgtagaa gatccaaatg gtatatctga tacaaaaact aaagggtata
    10681 tcgaatttca aaatgtaaca tttgcttatc caggccattc gcaagagcca gtgatacgaa
    10741 atgtcagttt tacagcctct ccaggagaga ccgttgcttt tattggaagt accggtagcg
    10801 gaaaatctac gttgatccaa ttgatccctc gcttttatga tgtgagtgaa ggaaagatct
    10861 tgatcgatgg agtagacgtg agagattatc ggctaagcaa gttgcgagat aagattgggt
    10921 ttattccgca aaaagcgctg ctatttactg gaacgattgc agataatttg cgatacggga
    10981 aagaagatgc tacgcaagaa gaaatggaac gtgcagctga gattgctcaa gcttcagaat
    11041 tcatttctcg aaaaccagat ggatttaatg aacatttatc agaaggtggt tccaattttt
    11101 caggtggaca aaaacaacga ttggcaatag ccagagccat catacgccgt ccggaaatct
    11161 atatttttga tgacagcttt tctgcattag attatcaaac ggatgcgaag ttacgtgctc
    11221 gtctgaaaaa agaaacgaca gaatctactg tattgatcgt agcacaacgt gtgggaacga
    11281 tcatgcatgc agataagatc atcgtattaa atgaaggaga agtcgtcggt atggggacgc
    11341 atcgggagtt gttggaaaaa tgcccgattt attatgatat tgccgcttct caattatcaa
    11401 aggaggaatt agcatgaaaa aaaccttttc ttccttaaaa cgtttagctc gatatatcag
    11461 accgtatcgt gagacttttc ttttagtgat cctatttaca gttctgacag tggctttcaa
    11521 cgtggctttg ccatatgtta caggacttcc tactacagaa atcagccgta atattgccaa
    11581 tggcgaatca atcaattttt cttatatatt caaatgtctc atttggatca cagttgttgg
    11641 aatagggtat tgtatttcgc aattactttc tggtgttttg atgacaaatg tcgttcaaag
    11701 tgccatgcat gatttgagaa gagacataga agaaaaaatc aatcgtcttc cggtttcata
    11761 tttcgataaa aaccagcaag gaaatatttt gtctcgtgtg acgaatgatg tagatgcagt
    11821 cagcggtgct ttacaacaag cttttattgg tatcgtaaat gcgatattgg gaattacgtt
    11881 ggctgcagca atgatgtttt atatccagcc gatgatggcg ctgatctcta tgatcatgat
    11941 tccaacatcg atctggatct caaaacgagt gatcaatgct tcgcagaaat attttcaaag
    12001 catgcagaat tctcttggtg agctaaacgg ctacgtccaa gaaaatatga caggttttag
    12061 tgtattgaaa gtatatggac gcgaaaaaga aacattggaa ggattcaaaa aagttaatca
    12121 cagcttgaaa tactttgggt ttcgtgcagc attcatttct ggcttgatga tgcctctagt
    12181 tcaattaact gcctatgcta cttatattgg tatggctgtt ctaggaagct tttatgttat
    12241 tactggggcg atcgttgtcg gtcaactaca agcattcatc caatatattt ggcaaatcag
    12301 tcagccaatg gggaacgtga cacaattgtc ttcagttttg caaagtgcat cagcggcaac
    12361 gaaacgtgta ttcgagattt tagatgagcc agaagaaaaa gaaaacaaag tagatgcttc
    12421 actgccagaa acgattttag gagatgtgac attcgatcat gtcgattttg catatgatcc
    12481 gaagaaacca ttaatccaag atttgaattt tgaagtgaaa gctggtcaaa ccgtagctgt
    12541 ggtcggtccg accggtgccg gcaagacgac attgatcaat ctattgatgc gtttttatga
    12601 cgtagacaaa ggagcaataa ggattgatgg aatcgacacc aaatcaatga gtcgcagtga
    12661 tgtgcgttcg ctatttggta tggtcttgca agatgcatgg ctttatcaag gaacgattgc
    12721 agataatatc cgcttcggaa agcttgatgc gacagattat gaagtagttg atgctgcgaa
    12781 aacagcaaac gtagatcatt ttatccgaac gatgccagat ggatatgata tggccatcaa
    12841 ttctgaggga gacaatgtgt ctttaggaca aaaacagttg ctgacgattg cccgagcagt
    12901 ggtctccgat cctaaaatct tgattttaga tgaagcaaca agttcagtag acacccgttt
    12961 agaagcgttg attcaaaaag caatggatcg cgtgatggag ggacggacaa gtttcgtcat
    13021 cgctcaccgt ttatcgacaa tccgtgatgc agatctgatt ctagtgatgg atcaaggtca
    13081 gatcattgaa aaaggaacgc atgagagttt attggcacaa ggtggatttt atgaaaaact
    13141 gtataacagc caatttgctg aggaagcaga ataagtcata taagaataaa acagtttaaa
    13201 acttattttt tgttctctat tcttgataat ggtaaagtaa agttatcaag aaaagtgagg
    13261 acacggagat ggaacagttt ttaaatgaaa aaattactga agccaaaaga gaagttgatc
    13321 gtttaacgca cgtctgtcag acgaagcctt ttgattcagc tgattttttt gaaaatgagt
    13381 ttcaaatcga acgcttggca gcacaaatag aagtgtacga attaatttta aaaaaagtaa
    13441 tagaagaaaa tatagatgta caataaaaac aggtaaaacg tcagttacca gatactgtaa
    13501 atagacatct ggcctgagca ggttttacct gttttttttc ttatgaaata aatatatgct
    13561 atgatacctt tattcaatag gattagtttc tacaaaaaat gaaaggagaa aaataaatat
    13621 ggaacggttt atagcatcaa atgccacagt gattggtgat gtgacattgt cagaagatgt
    13681 gacgatctgg tatcaagctg ttttacgcgg ggacagtaat tggataaaaa taggacaaag
    13741 aacgaatatc caagatggta caatcatcca tgtcgatcat gatgcacctg tagatattgc
    13801 ggagaatgtg acggtaggac atcagtgcat gctacatggc tgtacaatcg aaaaaggggc
    13861 gctgatcggg atggggacca cgatattgaa tcatgcggtt attggtgaga atagtttgat
    13921 tggtgctgga tcattagtaa cagaaggaaa agttattcct cctaatgtct tggcttttgg
    13981 tcgcccagct aaagtgatcc gtcctttgac aaaagaagaa atacaaaaaa acaaagaaaa
    14041 catccagcat tatgtcgaga taggtcggat gcatgcgcaa ggaaaattca aggagcaaag
    14101 ataggcagta gcatccataa aataaaaaag gatggtcagt ttgagttgac catccttttt
    14161 tatttggttt agataagaga gcttaaaaaa gcttcctttg aaacagatta atttaatgaa
    14221 gaactgtttt ccatgacttc atcgatcaat ccatatgctt ttgcttgttc agctgtcata
    14281 tagttgtcac gatctgtatc tttttcaatc acttcaagcg gttgtccagt gcgttcagct
    14341 aaaattttgt ttaagcgttc gcgtgtttgc aaaatatggc gtgccgcaat ttcgatttca
    14401 gttgcttgcc cttgagcgcc gccaagaggt tgatggatca tgatctcagc atttggtaaa
    14461 gcaaatcgtt taccttttgt accagctgtc agcaagaagc ttcccattga agcagccata
    14521 cccataacaa ttgtttggac atctgctttg acaaagttca ttgtgtcgta aatagccata
    14581 cctgctgtaa ctgaaccacc aggagaattg atataaagat agatatcttt ttcagaatct
    14641 tgagcgtcta agaaaagcaa ttgggcgatg atcgaattag caagatcatc tgttacttgg
    14701 ccgcttaaca tgatgatacg gtctttcaat aaacgtgagt agatatcgta agctctttca
    14761 cctcgtgaag attgttcaat gactgtagga attaaattca taatagagtt cctccttgat
    14821 ttcgtttaga aatagtgtac cataatttag tttctaatac ctaaaatgta gtatacattt
    14881 ttggtcaaaa aaggtcaaat aaaaaactta ggcaaattag tcgcataaac ccgctttatg
    14941 gtatgataag cagagaaaca aaacaaggag gaacaacaga ttgatagttg gtattactgg
    15001 ccttatcgga gtgctgacag gtgctgtagt tgtctatatc ggcatgatac tgcaaatgcg
    15061 tcacttggaa aataaagaac agcgtagacg tgaattggaa ttgaaagtca aagaaatcga
    15121 gacgctgaat caattaaata aaaagatcaa cgagatcttg caaaaacgga caacgctgat
    15181 ggaagaatat gtcagctttg atgcatttga tgattgttat atcacgattg acgattttgc
    15241 gtatctccaa tcattttcag cgcaaaatag tttttatctg ccaaattata ttttagacga
    15301 gctatttaag aatatctccc atcgaaaagt gattttatct ccagatgaaa caatgaagat
    15361 tggtggatat gcttataaag gcggacgcgt gattttagag aattttacgg atagtctgac
    15421 tgaaatgatc aatgaaaaaa aagctcagtt gaagactatg acgcgccagc cgattggttt
    15481 cttctcgaaa gatgatgttt ggagctgata ttttgaagca ttgccgttgc acatgagagc
    15541 gtggtaatgc tttctttttt tcttaatgat acaatagaac tgaacggagt gaagaaagat
    15601 gttacaaatc tatgcccatc gcggaagcag cggcacccac ccagaaaata cgcttcctgc
    15661 atttgcagaa gctgtacgag taggtgcaga tggtatcgaa ctagatgtcc atctaagcaa
    15721 agatggttat ttgatcgtta tgcacgacga agaagtggac cggacgacta acggtaaagg
    15781 gctgattcga gaaaaaacat tggaagaact caaaaaattg aatgcagggg gcaaattcag
    15841 caaagaattt ccagcagcta aagttcctga attgagagaa gtgttaggac tgctcctcca
    15901 aaaaaattac cgagggatgc taatgattga aattaaaact gatcagtatg aatatcccgg
    15961 tatcgaagaa aaattagccg aaacattaaa aagtagagat tggccttttc aacatgcata
    16021 ttgcagcttt catttggatt ctttggaaaa aatcgcatta ctggaaccgg agatacagct
    16081 ggacttattg atgagtactt ctgataaaaa gatccaacta gcagcagaaa ccccttatat
    16141 agaaggagta catccaaaaa atacttggtt gttcgaacat ccagtccagg cagctgattt
    16201 tccaaaagca attcgtgcat ggacgattaa cgatgaagaa gaaatggcca aatgtcaaga
    16261 actcaaaata gatggaataa taactgattt tccggagaaa gctcttcggt ggaaacaatc
    16321 aacgaaaagt aggtaaaata tggaaaaagt attagtgatc gtcggtccga cagcagtcgg
    16381 taaaacagcg ctaagtgtgg aactcgcaca actatttgga ggagagatca tcagtggtga
    16441 ttcattgcaa atctataaaa atctggatat cggtacagca aaaatcaaag aagaagagat
    16501 gaataatgtt ccgcatcatt tgattgatgt gatcgaacct actcaacgtt actcagccgc
    16561 tgattttcag cattcaggtc gacaattgat taccgagatt gcgaaccgag ggcacctacc
    16621 tatcatagct ggtggtacgg gtctctatat ccaatccctt ctatatgatt atcagttagg
    16681 agcgacagaa gaagcgaatc ctgagattag aaaaaagtat gaaacgttag ctgaaacaat
    16741 tggttcccaa gcattatgga atcagttgaa agaaaaagac ccggcagctg ctgagaaaat
    16801 ccactggaac aatcaacgca aagtgataag agctctggaa gttttagaga cgacaggaca
    16861 tagtatcacg gcacctaaag aagagccaaa gcaattgtat gattacctca tgattggatt
    16921 agatacgaag cgtagtattc tttatgaacg aatcaatcaa agagtcgatt tgatgctagc
    16981 agaaggttta gtagcagaag cgcgtaaggt gtatgagctt ggagaagtcc aggccagtca
    17041 aggtattgga tataaagaat ttttccctta ttttgaaggg aaagaaacat tggaagaagc
    17101 aacagaacaa gtcaaactac attcgagaag atacgcgaaa cgtcagttga cgtggtttcg
    17161 taaccgtttg gatgcacagt ggtttgatct tataagtgag ccaaatcaaa aaagtcagat
    17221 tgagcaaaca atcaaaaaat ggctggaggc ggaataaaat ggaagaaaaa gtgatcatcg
    17281 taggggtaga aaccgaagca aaccagcgtt acttttcaga gtcaatggaa gagctagttc
    17341 agctgacgaa taccgcatca ggagaagtcg tattcacaat tacacaaaag agaccacaag
    17401 tggatcggca aacgattatc ggtaaaggga aattacaaga attagttcaa caagcggatg
    17461 cgcatgaagc ggatttgatc atctttaatc atgagctaac tccgagacag agccaactga
    17521 ttaccgatgc tgttggtctt ccggtaattg atcgcgtgca gcttatctta gatatttttg
    17581 cgatgcgtgc tcgttcgaaa gaagggaagc tgcaggttga acttgctcag ttagaatacc
    17641 tgctgcctcg tttagtaggg caagggaaaa cattatctcg tcttggcggt gggatcggaa
    17701 caagagggcc aggtgaaaca aagttagaaa cagaccgccg acatatacgg aataaaattt
    17761 ttgctgttaa gaaagaattg aaagaagtag aagctcatcg agagcgcaat cgccaaaaaa
    17821 gaaaaaatag cgagattttt cagattggac ttattggcta cacgaatgcc gggaagtcaa
    17881 ctatcttgaa tctattgaca caagcggata cttattcgaa agatcaattg tttgcaacgt
    17941 tagatccatt gactaagaga tggcgttttg ctgaaggatt tgagattact gtaacggata
    18001 ccgtcgggtt catccaagac ctgcctacgc aactgatcga tgctttccat tctacattag
    18061 aagaaagtca aaatatggat cttttgctac atgtagtcga tgctagttct ccagatcgta
    18121 ttttacagga gcagactgtc ttaaaattga tggatgaact gaatatgaaa gaaatgccga
    18181 tactgactgt ttacaataag gcagaccaga tcgacccagc gatgttcacg cctacgctat
    18241 tcccaaatgt attgatttct actcagacga aagaaggtaa gatggcgttg atcgaagcaa
    18301 tcaaacgtca gctgatggaa ctaatgaccc cttatacact ttctgtgcca agcaacgaag
    18361 gacagaaatt aagcgagttg agaagacaaa caatggtttt ggacgaagcg tacatggaag
    18421 aaacaaacga atatgaagtt aaagggtttg caaaaaccaa ttcaaaatgg ttaagaaaaa
    18481 accaataaaa ttttattttt ttaa
//
LOCUS       DBBGSP010000056        17813 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000056 DBBGSP010000000
VERSION     DBBGSP010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.056"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            289..1146
                     /locus_tag="ACIZE9_002309"
     CDS             289..1146
                     /locus_tag="ACIZE9_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGC6094137.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1261..2181
                     /gene="pstC"
                     /locus_tag="ACIZE9_002310"
     CDS             1261..2181
                     /gene="pstC"
                     /locus_tag="ACIZE9_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGC6094138.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2181..3065
                     /gene="pstA"
                     /locus_tag="ACIZE9_002311"
     CDS             2181..3065
                     /gene="pstA"
                     /locus_tag="ACIZE9_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGC6094139.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            3080..3886
                     /gene="pstB"
                     /locus_tag="ACIZE9_002312"
     CDS             3080..3886
                     /gene="pstB"
                     /locus_tag="ACIZE9_002312"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGC6094140.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3902..4660
                     /gene="pstB"
                     /locus_tag="ACIZE9_002313"
     CDS             3902..4660
                     /gene="pstB"
                     /locus_tag="ACIZE9_002313"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGC6094141.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4673..5350
                     /gene="phoU"
                     /locus_tag="ACIZE9_002314"
     CDS             4673..5350
                     /gene="phoU"
                     /locus_tag="ACIZE9_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGC6094142.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5496..6617
                     /locus_tag="ACIZE9_002315"
     CDS             5496..6617
                     /locus_tag="ACIZE9_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HGC6094143.1"
                     /translation="MQAFEHCLFGKGFVTKYVTNPFHHFIERIKNAKKISIITIFFIC
                     VLTSWVIQHQAALYEVPVIEIEKVRIKEDHQLITGRLMNTNQKGESIYLSVPYQKNQI
                     ETANIKARQMYLVQMHGDEWQLVAKKNDGWLFFFTSIFIGAMLLIGGKHGLFALGSLI
                     INIVLLLLLLLIFTKIEGISLLNISILFVVIGMIISILALDGWNRSSIIKISAAVTSV
                     FLAFFICLLTMNLWKDQGLRYEELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATL
                     EELTKRQPEITAKQLWLSGRQVGRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKE
                     TIEQHLSLEFLRVIAGSLGIVLSIPISVLFFLTVRRLKR"
     gene            6614..7381
                     /locus_tag="ACIZE9_002316"
     CDS             6614..7381
                     /locus_tag="ACIZE9_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HGC6094144.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTTIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7481..9049
                     /gene="liaX"
                     /locus_tag="ACIZE9_002317"
     CDS             7481..9049
                     /gene="liaX"
                     /locus_tag="ACIZE9_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HGC6094145.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            9346..9666
                     /locus_tag="ACIZE9_002318"
     CDS             9346..9666
                     /locus_tag="ACIZE9_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGC6094146.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9666..10016
                     /locus_tag="ACIZE9_002319"
     CDS             9666..10016
                     /locus_tag="ACIZE9_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HGC6094147.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10183..11121
                     /gene="hprK"
                     /locus_tag="ACIZE9_002320"
     CDS             10183..11121
                     /gene="hprK"
                     /locus_tag="ACIZE9_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGC6094148.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            11136..11966
                     /gene="lgt"
                     /locus_tag="ACIZE9_002321"
     CDS             11136..11966
                     /gene="lgt"
                     /locus_tag="ACIZE9_002321"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGC6094149.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            12010..13035
                     /locus_tag="ACIZE9_002322"
     CDS             12010..13035
                     /locus_tag="ACIZE9_002322"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGC6094150.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHCLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPVEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            13050..13988
                     /gene="galU"
                     /locus_tag="ACIZE9_002323"
     CDS             13050..13988
                     /gene="galU"
                     /locus_tag="ACIZE9_002323"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGC6094151.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            14113..14553
                     /locus_tag="ACIZE9_002324"
     CDS             14113..14553
                     /locus_tag="ACIZE9_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HGC6094152.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14556..15158
                     /locus_tag="ACIZE9_002325"
     CDS             14556..15158
                     /locus_tag="ACIZE9_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGC6094153.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIIIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15217..16323)
                     /locus_tag="ACIZE9_002326"
     CDS             complement(15217..16323)
                     /locus_tag="ACIZE9_002326"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HGC6094154.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRTRYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16533..17534
                     /gene="ccpA"
                     /locus_tag="ACIZE9_002327"
     CDS             16533..17534
                     /gene="ccpA"
                     /locus_tag="ACIZE9_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGC6094155.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLADRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEGFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
BASE COUNT         5817 a         3078 c         3836 g         5082 t
ORIGIN      
        1 ttttctaacg gggccatttc tgagagtacg tcagaaatgg agaaagcgtc tcgcatgagc
       61 gaaattaact ttggggtatc tcttgttttt tggggaaagc aagaaataag ctaatatatg
      121 ctattaaaag agacacattt caaagccagt atagcataga aacttttaat gagatagttt
      181 tttttacaat tatgaggatt tattttgtta tttaatgatt ttgattcgtt ttcatcaagt
      241 aatgaaaatg ataaaataaa catactttag gattaaagga gatttctaat gaaaaaactt
      301 aaattattct taccaataat aggattagct attcttttat caggctgttc aaagtggatt
      361 gatcgaggag aatccattac ggctgttggc tcttctgctt tacagccttt agtagaaaca
      421 gttgctgaaa cttaccagac agaaaatcct ggaaaattca tcaatgtaca agggggcgga
      481 agcggaactg gtttgtctca agtacagtca ggagcagtcg acatcggaaa ctctgatttg
      541 tttgcggaag aaaaatcggg gatcgatgcc tcagcattag tcgatcatcg agtagcagtt
      601 gttgggatca ctcctattgt gaacaaggat attggcgtaa aagacatcag tatggaaaac
      661 ctgaaaaaac tatttacagg cgagatcaaa aactggagtg aagtcggtgg aaaagatcag
      721 ccagtagtta tattgaaccg tgcttcagga agcggaaccc gtagcacgtt tgaaaaatgg
      781 gtattggacg gagaaacagc tgttcaggca caagaacaag attcaagcgg aatggtgcgc
      841 cagatcgttg ccgacacacc cggtgcaatc agctatgttg ctttttctta tgtttccgat
      901 gatgtagata cgttgaatgt taacggtgta gaaccgacag atgaaaatgt gacaacgaac
      961 aaatggacga tttgggcata tgagcatatg tacacaagag atcatccaaa aaaactgaca
     1021 aaagaatttt tagactatat cttatctgat gaagtacaag ataacatcgt tggagaacta
     1081 ggttatatcc ctgtttctca tatgaaagtc gaacgtgatt ggcaaggaaa tatcgttaaa
     1141 gagtaatctt tacacaaaat ttacaaactt agctaaactt ttacatgtta ttaaaaccaa
     1201 attgatgttc aatttgtaca ctgagtgagt atgttaaacc tgattaaggg ggagtcatct
     1261 gtggaagatg tgaaaaaagt attattaaca aaatcaaaac gttcaaaaat ggaacagcgt
     1321 ggaaaattca tcagtttttt atgtatcgcg ctgatcgtgt tggttgtatt atctattttt
     1381 tattttgtag ctagtaaagg attggccacc ttttttactg ataagatcaa tgtatttgat
     1441 tttctgtttg gtacagattg gaatccaagc caaatcggag caaatgggaa accaatggta
     1501 ggggcattgc ctatgatcac aggttcgttt attgtgacct ttttatctgc tattgttgcc
     1561 acaccatttg ccattggtgc agcagtattc atgacggaga tctctcctaa aaacggaacg
     1621 aagatcttac agccggtcat cgagctgctt gtaggtattc cttctgtcgt ttatggtttt
     1681 atcggtttat cagttatcgt gccttttgtc agaagtattt ttggcgggac agggtttggt
     1741 atcttagctg gtacatttgt gttgttcgtt atgatcttgc cgactgtcac aacgatgact
     1801 gttgatgcat taaaggcagt accacggcac tatcgggaag cttcattagc gcttggtgcc
     1861 acaagatggc aaacaatcta caaagtcgtg ctacgagcag ccgtgcccgg gattttaaca
     1921 gcagtcgttt ttggtatggc tcgtgcgttt ggtgaagcct tagctatcca aatggtcatc
     1981 ggtaatgcag cattgatgcc aacaggactt actactcctg cttctacatt gacgtccatc
     2041 ttaacaatgg gaatcggaaa tacaatcatg ggaacagttg aaaataatgt gttatggtca
     2101 ttagcgctga tcttgctatt gatgtcatta ttctttaata tcgtgatccg tatgattggg
     2161 aagaaaggag agctgaaata atgaacgcaa aacgctcaga taaaattgct acaggtgttt
     2221 tatatgtagt ttcggggatc atcgtattga ttttagcagc tttactactt tatatcttag
     2281 ttcggggaat accgcacatt tcatggtcct tcttgaccga accttccaaa gcctaccaag
     2341 aaggcggtgg aatcgggatc cagctattta actcgattta tttgcttttg atcacgatga
     2401 tcatcagttt tcctatttct ttaggtgcgg gtatctatct ttcagaatat gctggaaaaa
     2461 actggctgac agatgtgatt cgcacgtcga ttgaaatctt gagctcattg ccttctgtcg
     2521 ttgtcggttt attcggtttc ttggttttcg ttattcaatt ccagtatggt ttctcgatta
     2581 tttctggtgc attggctttg actgtattca acttgcctct tttgactaga acagttgagg
     2641 agtctttaca agcggtccat tacacacaac gagaagcagg attggcttta ggtttgtcac
     2701 gctgggaaac agtgataaaa gtggtggttc cagaagcgac accagggatt ttgactggtg
     2761 tgatcctaag ttctggaaga atttttggtg aagcagctgc attgatctat acggctggac
     2821 aaagtgcacc tgcgttagat tttacgaact ggaatccatt aagtgtttca agcccgatca
     2881 gcattttccg tcaagctgaa acattagctg tccatatttg gaagatcaat acagaaggca
     2941 cgatgcctga tggtgtttct gtttcggctg gcgcttctgc cgtgttgatc attgctgttt
     3001 tactgttcaa cttcggcgct cgtgcgattg gcaaacgatt ataccgaaaa atgacttcag
     3061 cctaaggaga agaagcaaaa tgaaaaaata taactggaat gaaacaaatg tcatcaccat
     3121 gccaaaagag aaagaagtag cactatatac ggatgatcta catgtctggt atggcgacaa
     3181 tgaagcaatc aaaggagtgg atctggaatt tgaaaaaaat aagatcactg cactgattgg
     3241 tccttccggc tgcggaaaat ctacgtatct tcgttcgttg aatcgaatga atgatgggat
     3301 cgctaatacg aaaatcactg ggaaaatcat gtatcaaggc gtagatatta atgcgcctca
     3361 agtggatgtt tatgagatgc gcaaacggat tggcatggtt tttcaacgtc ctaatccgtt
     3421 cagcaagtcg atttatgaca atattacatt tgctttgaaa cagcacggcg aaaaaaacaa
     3481 aaagaaatta gatgaaatcg ttgaaacaag cttgaaacaa gctgccttgt gggaccaagt
     3541 aaaagacagc ttggacaaaa gtgccttggc tttatctggc gggcaacagc aacgtttatg
     3601 tattgctcgt gcgatcgcga tgaaacctga tatcttgctg ctagacgagc cggcaagtgc
     3661 tttggaccct atttcgacag gaacggttga agaaacactt gtaaacttga aagaagacta
     3721 tacgatcatc atcgtgacgc ataacatgca acaagcggct cgtatcagcg actatactgc
     3781 ctttttctat ctaggaaaag taatggaata tgacaaaact aacaagatat ttaccagacc
     3841 aaaaattcag gcaaccgaag attatgtgtc cggtcatttt ggttaagacg gaggcctcaa
     3901 catgacaaaa gaaattattt catctaaaga tcttcatctg tattatggaa agaaagaagc
     3961 actaaaaggg atcgatctaa gtttcaatca aggggaaatc actgcgatga tcggtccttc
     4021 tggttgcggg aaatccactt atctgcgttc tttgaaccgg atgaatgacc tgattccgaa
     4081 tgtaacgatc accgggagtg ttttatataa agacaaagac atctatggtc caaaaacaga
     4141 tgttgttgaa ctaagaaaag aaatcggcat ggtattccag cagccaaacc catttccttt
     4201 ttctatctat gaaaatgtca tctatggatt gaaattaaaa ggggaaaaag ataaaaaagt
     4261 ccttgatcaa gtagttgaag aaagcctgaa ggcagcgtct gtttgggatg atgtgaaaga
     4321 caaattgcat aaaagtgctt tatctttatc cggtgggcag cagcagcgtg tatgtatcgc
     4381 acgtgttttg gcagttaatc cggaaatcat cttattggat gaaccaacaa gtgcgcttga
     4441 tcctgtttct actgggaaaa tcgaaagtat gctgttagaa ttaagagagc ggtatacgat
     4501 gatcatcgtg acccataata tgtctcaagc ttcacgtatt tcagataaga cggcattctt
     4561 tttagatggt cacttgatcg aatacaatga tacgaagaag atattcatga atccagaaaa
     4621 acaagagaca gaagattata tttcaggtcg atttggataa ggaggaaacg gaatgctacg
     4681 tacacaattt gaagaagaat tgctgaatct ccataatcag ttctacgaaa tggggatgat
     4741 ggtgagcagc gccgtgcaca agtcagttcg tgcatacatc aaacacgata aaatcttagc
     4801 ccaagaagtt atcgaaaacg atataaatat caataacatg gaaacacgct tggagaagaa
     4861 aagttttgaa atgatcgcat tgcaacagcc agttacaact gatttgcgta tgatcattac
     4921 ggtcatgaaa gctagctcgg atttagaacg tatggccgat catgcggtgt ctgttgctaa
     4981 atccacgatt cgcgtaaaag ggcagacgag aataccggaa atcgaaaaag agatctccga
     5041 tatgtccgat tatgtgaaaa aaatggtgga caacgtccta gttgcttatg tcaaaacaga
     5101 cgaaaaagac gcacgtacga tcgccaatat ggatcaaaga gtcaatgact atttcaatcg
     5161 aatctataat gcaacaatca aaaatatgca ggaaaatcct gagacagtca tcagtggaac
     5221 agactacttg aatgttgcca gttatctaga acggatcgga gactatgtga caaacatctg
     5281 tgaatggatc gtctacttgg ctacagggaa aatcactgag ttaaatacga accacaatga
     5341 gattttctaa actaaagcgg tgattctgcc gtttgtttag gaaaagaggt tgtgaaatca
     5401 gcggttgtga aaaagctgtt ctgcatcaag taataagaac agtcaaacaa aaatagctcc
     5461 tcatattttt catttggctg gacttattac cgcagatgca agcttttgaa cactgtttat
     5521 tcgggaaagg gtttgtgaca aaatatgtca caaacccttt tcatcatttc atagaaagga
     5581 taaagaatgc aaaaaaaatt agcatcatca ctatattttt tatttgtgtg cttacttcat
     5641 gggttattca gcatcaagct gctttatatg aagtacctgt catcgagatc gaaaaagtac
     5701 gaataaaaga ggatcatcaa ttgattacag gaagactgat gaacacgaat caaaaaggag
     5761 aatcgattta tttatcggtt ccttatcaaa aaaatcaaat agaaacagca aatataaaag
     5821 cgagacaaat gtatctagtc caaatgcatg gagatgaatg gcagctagta gcaaaaaaaa
     5881 atgatggctg gcttttcttc ttcacaagta tcttcattgg cgccatgttg cttattggcg
     5941 gaaaacatgg tctatttgct ttaggaagtc tcatcatcaa tatcgtttta cttttacttt
     6001 tgttgctcat ctttactaaa atagaaggga tttctctatt aaatatatct atcctgttcg
     6061 tcgttatagg gatgattatt agcatattgg ctttagatgg atggaataga agcagtataa
     6121 tcaaaatttc agctgcagtt acgagtgttt ttttagcatt ttttatttgt cttttgacaa
     6181 tgaatctttg gaaagaccaa ggactgcgct atgaggaact gaattatctg acacgaccgt
     6241 atcgttctgt ttttctttct agcgtactga ttggaacagc tggaggaaca ctcgataccg
     6301 ttatcacagt cattgcgaca ttagaagaat tgactaagcg acaaccagaa ataacagcga
     6361 aacagttatg gctttcggga aggcaagtgg gtcgagatgt gattggctcg atgaccaata
     6421 tccttttgtt cgtctatatc agtgggtcag ttccatcgct tcttttatat ttaggaaatc
     6481 aatggtcgtt caaagaaacg atagaacagc atttatcatt ggaattttta cgcgtcattg
     6541 ctggcagctt aggaatagta ttatcgatcc ctatctcggt cctctttttt ctgactgtaa
     6601 ggaggctgaa acgatgaatg tacttattat acttgttggg attttagcaa tcagcgtgct
     6661 acttattggc ggtacgcaag gtatgtatat tcttttaggc ttattcatca atttagggat
     6721 ctttttcttg ttgttattcg gttatcatca gaagtggccg atactggcat tgtcggtcat
     6781 aggattttta ttgattgctg tggttatctt attttttatc aacggttata atctaaaaat
     6841 gcgtgcagct tttgtgagta tactgatctt tttattttgt ttcctactat tgcttcctat
     6901 cactgatttt ttagcaatcc aaggttttac aacgatagaa ctagaagaat tatctggctt
     6961 agataagact ttagcgattg attttagatt acttacgaga tcgttgcttc tgattagtct
     7021 tagtggtgct gttttagatg cgagtgtagc aatttctagt gggacattcg aagtatatca
     7081 ggcaaatccg caattatctt tttaccaatt gcgccattct agtttcgcta ttgctaaaaa
     7141 aatattggcg tcaacagtaa tgacacttct ttttgcattc atgggaagtt ctttagcgtt
     7201 gatcctctgg tttattgatt tagacattcc ttttcagcaa gtgatcaatg aaaaatcatt
     7261 tgttctagaa tatacgatgg ctattcttac cacattgtcc gcactacttg ttcttccttt
     7321 aacctgcgtg actacagcat atctctttac aaaaaagaaa gaacaactca agatggagta
     7381 aaagttacaa cttaagtcct atgacatttt tactgaatca gtgcataata tggatgtaag
     7441 gaaaagcttg caaacaattt tgcttaagga ggcaatttcc atgaaagaaa gagaacgtat
     7501 tttagattta gtgaaaaaag gaatcctttc gactgaagaa ggcttagatt tattagaaag
     7561 catggcaact gaaaaagacg aaaagcaaat caaaaaagaa gcagacaagg taactgctag
     7621 tcataaagaa aaagatcagg caagtcaatt gatcgataaa cttgaaaacg gcgaagaaga
     7681 aatttctgag ccagttgatc caaaggaaag agaaagacaa gatcaagaaa acttagaaaa
     7741 gatcttagat gaactagcaa ctgaagcgaa taaaacttcg gcgcgtctag atgaagtaaa
     7801 tgctcaattc gctgacaata aggcagcacg caatgagaaa caggaagcat tgatgcagct
     7861 gaatacaaaa gaagaattag gcgagttgac agaagaagaa ttagcacagc gtcagacgtt
     7921 agaagcagaa atcaaagagt tagaagctag tggcgataca ctgttagaag aacaattgaa
     7981 attagaagca gaattaaaag atatccgtaa gaatcaatgg tctgagaaaa aagaaacgtt
     8041 tactgataag tttgaattgc cagatgattg gaaagatcaa gcaacagata cactgaatca
     8101 agtaggcgaa aaaatgtcag aagctggatc acagttagga aaattcttga agaaaacatt
     8161 ccaaactgtt tcagaaacag tgaatgacaa catggaatgg aaagatgtca gcttgcgtgt
     8221 ccctgggatt gcgacaacga aatttgagca tgaattttac tatgaagctc ctgcagcaag
     8281 tatccttgat atcaaggcag caaacggaaa cgtgacgtta aaaacgtggg acagcaacga
     8341 tgtgaaagtt gaagctaaga tcaaacttta cggaaaaatg ggtgctgaac catttgaagc
     8401 attctctgaa cggagccaga ttgaggttaa tgaagatcat atctccttcc aaattccaaa
     8461 taaacgtgtg cgtgcagacc ttgttttcta cttacctaaa cgagtatacg accacgcagc
     8521 tattaaactt ctaaatggca acatcatgat tgaaacattg gaagctaaag atatttatac
     8581 aaaatctacg aatggtaaca tcatcgtgga ccaattaact gcaacgatgc tggaagtaga
     8641 aggtgtaaac ggcaatatcg atattcgaaa cgggaacatc ttagattcta ttatcgaaac
     8701 agtaaatggt acagtgacat ttggtgcgac agcagaaaac ctttctgtgt ctttggtaaa
     8761 tggtgatgta cgtcttacga ttaaagaaga taatttgaaa aaagtagaag caagttcagt
     8821 gaacggaaat gtcaaagtcg ctttaccaga tggcatcggt ttggaaggac atgctaaaac
     8881 aagtcttgga agtatcaaca gccgtctgtc caattacgaa gtagttcgtg agaaaaaaga
     8941 acggacaaac caaatgttgc aattccgtcg tgtttcagat ggtgaaatcg cgcaagtgca
     9001 actttcaacg acaacaggaa gtatctattt aaaagataca gataaataaa gaggttgtga
     9061 aagagatgtt cagccttgag caataagaag cgattttgta aaatagcttc ccctatttta
     9121 caaaattgtg ccttattgcc gataggctat ctcttgaaca ccgtttacca agagattatg
     9181 aacttgccaa ttatcgccga gtcacaagga ataatttcaa aaaaagctcg tcacgtttta
     9241 tgaatatggt aatttgtgac cgagaatttt gcaaaaagac accgattaag aagaaggttg
     9301 tcacaacgat tttcttcatt taaaatagta gaacagaggt gagacatgat gaaaaaaaag
     9361 ttgacaaaat ccaataaaaa tgttgttttg acagggactt tagcaggaat aggagaatac
     9421 atcgggattg atccgactgt tatccgtgtg ctttatgtat tcctgagctt agttgctttt
     9481 ggaagtccaa tcattttata cattttatta gctttgatta tcccatctgc gcgttctgca
     9541 cgaacaaact atggacataa caatgcatat tatgaaaaaa acaattatcg tgaacaaact
     9601 cgtgaacaaa caaaaaaacg caaagaagcg gaaaaaatcg atgatgacga atggagtgac
     9661 ttttaatgtc gtactttcaa cgtattttag ttaatacgtt aacattcata tcattggctg
     9721 ttctttttcc tgcgatggtc catgtgagca gtatttggac ggccgttctt gccagcttcg
     9781 tattgtctgt gttgaatatg tttgtcaaac cgattttgac gatactgtcc ctgcccttta
     9841 cattagtcac attgggattg tttacgtttg ttatcaatgc agcgattctt aaaatgacct
     9901 ccttttttgt gggagcagaa cattttagtt tttcttcatt cggtgcagcg ttgttagtag
     9961 ctatcttgat gtcgcttgtc aatgtaattg tcagcgaaca taacagtaga aaataaaaga
    10021 aagctgtgcc gaactatcgg cgcagttttt ttatttagaa tcaggaatgc gttttctatt
    10081 acattggtaa ttaaataaaa acgttttttt taattggtag tacttttggc tagacaatga
    10141 taaaatgata gagaacactc taatagaaat gaggtagcat gaatgtcaga agttgtaaaa
    10201 gttagccaat tagtgaaaaa attatctttg gaaatcgtga caggcgacga gaaaagctta
    10261 gaccgtgtca tcgtaactgg ggacatctca cgcccaggac tagagttgac tggttatttt
    10321 aattattatt cccataatcg tttacagcta tttggcagta aagaaatcag ttttgcggaa
    10381 cggatgatcc cagaagagcg tttgatcatc atgagaagat tatgtagtga agatatgccc
    10441 gcatttatta tttcaagagg attaccagct ccagaagaaa tgatccaggc agcaaatgaa
    10501 aatgggatag ctgtactgcg ttctcccatc tcaacttctc gcttattagg agaattatcc
    10561 agttatttag atggtcgcct tgcccctcga acaagtgtcc acggtgtttt agtggatgtt
    10621 tacggattag gtgtactgat tcaaggtgac agtgggatag gaaaaagtga aacagcgttg
    10681 gagttgatca aacgcggtca tcgattgatc gcagacgatc gagtagatgt ttatcagcaa
    10741 gatgaattaa cggtgatcgg agaaccgcct aaaatcctgg aacatctgat tgaaatccga
    10801 ggaatcggga tcattgatgt aatgaatctt tttggtgcga gtgcggtacg tggctctatg
    10861 caagtccagt tggctgttta tctggaagca tgggcaaaag ataagaaata cgaccgtctg
    10921 ggctctgaag acacgaccgt tgaaatcgcg gaagtaggca ttccacaaat aaaaatccct
    10981 gtcaaaacag gacgaaacgt tgcaatcatc attgaagtag ccgcgatgaa tttccgtgca
    11041 cgtacaatgg gctttgacgc aacgaaaaca tttgaagaaa gattaagtcg cttgattgaa
    11101 gaaaactcag gcaacgacta gcaaggagtg acaatatgtt agcacaaatc aatcgagttg
    11161 cttttgagct tgtagggatt cctatctact ggtatgcatt gatcatcgta tcaggtatca
    11221 ttatcgccat gtggcttagc agcagagagg ctgttcgggt aggattaaaa gcagatgatg
    11281 tgacagattt tatgttgtgg ggattgccta tctccattat tggcgctcgc ttatattatg
    11341 ttttatttga tcttccccag tatatagctg atccaatcca aatattcaat atccgttcag
    11401 gaggcttagc tatttatggc ggactgattg caggcgcgat cacgctgtat ttttttacta
    11461 aatatcattt tatttctttg tggacttttt tagatatcgc tgcaccaagt gtattattag
    11521 cacaagcaat cggtcgttgg ggaaatttca tgaaccacga agcatatgga ccagacacga
    11581 cgcgaagctt cttagaaagt ctgcatttac cgcaattcat cattgataat atgtatatcg
    11641 aagggatcta tcgtcaacca acatttcttt atgaatcact ttggagtttg attggattta
    11701 ttttgctttt gtttttacga aagaaaccac accttttgaa aaaaggtgaa gtccttttat
    11761 gttatctaat gtggtatagt ttcgggcgtt tctttattga aggattacgt acagacagtc
    11821 tttacttttt aggtgtgatc cgtatttctc aattattatc tgctgtgtta tttgtcggta
    11881 cattgattct atttatttgg cgcagaaaaa aaggaaattt accggattat gaccgctcat
    11941 taggaaaaaa tcaacaaatt atctgatttt tagagcgtta aaaatgaaaa aaatttcagg
    12001 agtggtaaaa tgaattatag agtagcggtt ttaggaccag gctcttgggg tactgctttg
    12061 gcacaagtcc tcgccgaaaa cggacatgac gttcggattt ggggacatcg tgcttcacaa
    12121 gtagaagaaa tcaacaccca acacacgaat caacgttatt taccagatca ttgtctaccc
    12181 gattccatcc aagcattcac caatatggaa gatgcagtaa aagacgcaga tgcggtgcta
    12241 ttcgtcattc caacgaaagc aatacgttct gttgcaaaag aactagtgcc taaattgaat
    12301 acaaagccag tgatcatcca tgcaagtaaa ggattagaac aggggacaca taaaaggatc
    12361 tctgacatct tgttagagga aatcccagta gaaaaaagaa aagctgttgt tgttctttct
    12421 ggaccaagcc atgcagaaga agtagcgaaa catgacatca ctacgatcac agctgcaagt
    12481 acagatgcaa aagcagcaaa atatgtacaa gagctgttca tgaataatta ttttcggatc
    12541 tataccaatc ctgatgtgat cggtgtagag atgggggcag ctttgaaaaa tattattgct
    12601 attggtgctg gcgctattca cggcttaggg tttggcgata atgcaaaggc agcaatcatg
    12661 acgcgcggat tagctgagat cagccgttta ggtgtagcaa tgggtgccaa cccgctgacc
    12721 tttatcggat taagcggagt aggcgatcta gtcgttactt gcacaagtgt tcattctagg
    12781 aactggcgcg caggcaactt gttaggacaa gggcagcccc tagaagaggt gctagccaat
    12841 atgggaatgg tcgttgaagg tgtgaatact acccaagcag cgatggaact agcccaaata
    12901 atggaaatcg aaatgcccat cactcaaaca atctatgaag tgctgtatga acaaaaagaa
    12961 atcaaaacag ccgcaaaaga aatcatgtta cgtgatggga aaaaagaaaa tgaattctca
    13021 ttaacaattt tttgaaggag cgaatgtata tgaaagtcaa aaaagcagtt attccagcag
    13081 caggattagg aacaagattt ttaccagcaa caaaagctat ggcaaaggaa atgttgccaa
    13141 ttgttgataa accaacaatc cagttcatcg ttgaagaagc gttgaaatca ggtatcgaag
    13201 acatcttgat cgttacagga aaagctaaac gaccaatcga agatcacttt gattcaaata
    13261 ttgaattaga aacaaaccta agtgaaaaag gaaagaccga attattgaaa ttagtagaag
    13321 aaacgacaga tgtcaacttg catttcatcc gtcaatctca tccaaagggt ttaggacatg
    13381 ccgttcttca agcaagagcc tttattggaa atgaaccatt tgtcgttatg ctaggcgatg
    13441 atataatgga agacgaagta ccattgacac agcaattaat cgatgattac gaacgtactc
    13501 atgcttctac gatcgccgtt atgcaagttc ctcatgatga aacttcaaaa tacggaatta
    13561 tcaatccagg agaagtattg gaagatgggt tatacaatgt caaaaacttt gttgaaaaac
    13621 cagatccaag caaagcacca agtgatttag ctattattgg acgttactta ttgactccag
    13681 aaatttttga tgtattgtcc gagcaacaac caggagccgg aaatgaaatc caactaactg
    13741 acgcaatcga tacattgaat aaaacacaac gcgtatttgc ccgtaaattc acaggtaaac
    13801 gttacgatgt cggtgacaaa tttggtttta tgaaaacaag tattgaatat ggtctaacac
    13861 atccagaagt aggtgcacct ttacgtgagt acatcctgtc tttaggtaaa acattagaag
    13921 cagaaggaag caagatcgat cataatccaa aaggaataac agaaatcaaa gaagaaaaga
    13981 aaaaataacc cttttttcta acgagcttca gctgctaatt gaataaaaag tagttgaagc
    14041 tcgtttttat ttgtttaaaa aacacgaaaa tgctatcctt atagaaaaga gagacaagaa
    14101 gggagtttga tcatgtcagg aggagaaatt gcaggattga tcgcagcaat cgcctttgcg
    14161 atacttgtcg tttttatcgt tcgtgtgttg ttgcaagttt ctaaaacttt agaaaaagta
    14221 gatcagactg tagcagaagc aaatacgacg atcgaaatcg tcacaaaaga cgtagatctt
    14281 ttgtctagac aagtagaagg cttactggtc aaaagtaatg aactgctctt ggatatcaat
    14341 ggaaaagtcg caacgatcga tccattgttc acagcagttg ctgatttaag tgaaagtgta
    14401 tcagaactta atcattctag taaaaacatc gcgacgaaag tcggcggaat cggtaaaacg
    14461 acagctaaag cgacggttgc cggaaaagtc ggtgggacag cgatgaaatt ttttaaaaac
    14521 aaaaaacata ctgaaacgac aggaggaaaa taaaaatggc taaaaaaggt ggatttttat
    14581 taggtgcagt agtcggaggc acagccgcag caatcgccgc gttattgtta gcaccaaaat
    14641 ctggtaaaga acttcgggat gaattagctg cccaagcgga tgatttgatg gatatggctt
    14701 cagattacac agatatggcg aaagaaaaat cgactgagtt aacaggtatt gcaaaagaaa
    14761 aagcgcaaga tctttctcaa caagcaggtg atctagcagg tagtgtcaaa caaaaagtaa
    14821 gtgaatcagc agatgaagca ggaagtgaat ctgacgatat cttgttaaat cttaaagaac
    14881 aatcagctga cttatctaat cgtttcaaaa aaacggcaga agatatgaaa aaacctgcag
    14941 atgaattagg aagtattgct aaagatactt cagaagatat cataattgat gtaaaagacg
    15001 ctgctggtaa agcaggagat actgtcaatg aaggaatgtc agaagcaaaa ccagttgcag
    15061 atgactcaaa agaaatgatg aaaatggcaa aagaagatgc gaaagaagct aaaaaagaaa
    15121 taaaagatac aatgacagat tcatctacaa atcactaaaa tcacaaattt atagaataaa
    15181 aaggtgggag cggactagct ctcacctttt ttactcttat ttttctaaaa caagtaattc
    15241 ttttggtgta gtcgtgaatg gcacacagcc atcgcttgtc acatatacac agtcttcgat
    15301 acgtacccct actttttcag gaatatagat tcctggttca agagagaagc acatcccttc
    15361 ttcgattact aagtcatttc cttctacaag ggaagggaat tcgtggacgg ttgttccgat
    15421 cccgtgacct aaacggtgat tgaaatattc gccgtagcca tagctgttga tcacgtttcg
    15481 tgcgatttga tcaagttcac ctgctgtcac acctggacgg acggcttctt gtgcggcaag
    15541 ctgtgcttca agagtgatgt tgtagatttt ttcttggaag tcggttggtt tttgataagc
    15601 aattgtacga gtagcatcac tgcaatagcc attccaaaca acgccaagat cgaataacac
    15661 aagttcattc ggtgaaatct tcgtatttcc tggtgtacca tgagggcttg cagcatttgc
    15721 tcctgcaagg actaatgtgt cgaaagacat ttgtgaaaca ccttgttttt tcaattggta
    15781 ttcaatttct gcaatgatcg cttgttcagt cacgccttct ttcactgctt taaagccaat
    15841 ctcaaatgca acatcggccc atttaccagc ttcgatcagt ttgtcttttt cctctagagt
    15901 tttgatcagt tgtagacgtt ggatgatgga agttagatca gtgtaagaat ccgttcccgt
    15961 caagatatca gagatagcat cgaagcgctc gacagtcaag gcgttctttt caatccctac
    16021 attgccaggc tgaccatagc gagtacgaag ttcttttccg atgatctccc aagggttttc
    16081 gctgtctaaa tagccgcgga catcatacgc ccaactactg ttttgagcat cttcaacttc
    16141 caaagcagga gtgaaaagga aaggatcttg ttcaagaggg ataaaaagag ctagtacacg
    16201 ctcatgagga tcactttcgt atccggaaaa gtaagcgatg tggccagggt cgctgatata
    16261 agccaattcg acttggtgtt gtgccatcca ttgacgtagt tcattgattt ttacgttatt
    16321 catttggcaa cctactttct aaattaattt tgtattcaat aattgtacca ctgatttatt
    16381 aaaagaccaa cgttctaaaa actgaaaaaa gtaaaaattt tcatgaaaac agagataaaa
    16441 cggttgcaat tcttgagatt atttgatatt ctattttaga aatgtaagac gtattttcag
    16501 aaaacatata aaatatgaat gggagaacac aaatggaaaa gcaaacaatc actatctatg
    16561 atgtagcgag agaggcaaat gtttcgatgg ctactgtttc acgtgtcgta aatggcaatc
    16621 caaacgttaa accagcaaca agaaaaaaag tcttggaagt catcgatcgc ttggattatc
    16681 gtccaaacgc agttgcgcgt ggcttggcaa gtaagaaaac aacaacagtt ggggtaatca
    16741 tccctgatgt cagcaatatg ttctttgctt ctttagcacg tggtatcgat gatgtggcaa
    16801 caatgtacaa atacaatatt atcttagcaa attcagatgg caacgaccaa aaagaagtca
    16861 atgtattgaa taacttactg gctaagcaag tggacggcgt gatcttcatg ggtcaccata
    16921 tcacagacga aatccgtgga gaattttcac gttcaaaaac tcctgttgta ttagctggct
    16981 ctattgatcc agatgaacaa gtaggtagcg taaacattga ttatgtatcc gcaacaaaag
    17041 atgcagtaaa taaattggca aaaagcggca ataaaaaaat cgcttttgtc agtggtgcgt
    17101 tgatcgatcc tatcaatgga caaaatcgtc tgaaaggcta taaagaagca ttaagcgaaa
    17161 ataacctacc atatagcgaa ggattgatct ttgaagcaca atacaacttc aaagatggtc
    17221 tatctctagc cgatcggatc cataatagcg gtgcaacagc tgtctatgtt tcagatgatg
    17281 aattagccat cggtattttg gatggtttat tagatcgtgg cgtgaaagta ccggaaggat
    17341 tcgaaatcat cacaagtaac aattcactac tgacagaagt agctcgtcct cgtttaacaa
    17401 gtatcacaca accattatac gatttagggg cggtatctat gcgcctattg acgaaaatga
    17461 tgaataaaga agaagtcgaa gaaaaaacga ttatcttgcc ttatggaatc gaagaaaaag
    17521 gatctacaaa ataataaaag gacaaccatt cagaggttgt gagcctgccg tttaactctg
    17581 cgttacaagg agcaatttca aaaaacagca tttcatgttt gatgaatatt gtgactcgtg
    17641 attcggagtt ggcaggagaa caccgtttat tcgggaaaag gggttatgac aaaattttgt
    17701 tataatcctt tttttgtgtc ttaaaaaaga gagaaagtgg ttgaaattac atttatcgta
    17761 tataaaacaa tccgtgtata gatgctgcat tttgttcacc accatcaaaa aaa
//
LOCUS       DBBGSP010000057        17674 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000057 DBBGSP010000000
VERSION     DBBGSP010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.057"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..199)
                     /locus_tag="ACIZE9_002328"
     CDS             complement(<1..199)
                     /locus_tag="ACIZE9_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094156.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
     gene            complement(362..1996)
                     /locus_tag="ACIZE9_002329"
     CDS             complement(362..1996)
                     /locus_tag="ACIZE9_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6094157.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            complement(2000..3373)
                     /locus_tag="ACIZE9_002330"
     CDS             complement(2000..3373)
                     /locus_tag="ACIZE9_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6094158.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            complement(3389..3628)
                     /locus_tag="ACIZE9_002331"
     CDS             complement(3389..3628)
                     /locus_tag="ACIZE9_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094159.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            complement(3810..6485)
                     /locus_tag="ACIZE9_002332"
     CDS             complement(3810..6485)
                     /locus_tag="ACIZE9_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HGC6094160.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            complement(6668..7591)
                     /locus_tag="ACIZE9_002333"
     CDS             complement(6668..7591)
                     /locus_tag="ACIZE9_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094161.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGTLGWTETYYEKIYKEIIEQYFPK"
     gene            complement(8114..9118)
                     /locus_tag="ACIZE9_002334"
     CDS             complement(8114..9118)
                     /locus_tag="ACIZE9_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HGC6094162.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKETVETDTTIEAKKSKTQS
                     TEQTTTEMKQSVEASTSESSIIESSSEEVKNTLWDSEKSTQLAIFVPQWGKTLGQEYK
                     SYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVET
                     GEYLGQHVYFFGFQNGQPKVYLTQQNQGNDKNYMYFNETQNQQLKQGFIDIVNGQTPQ
                     TPVVEESTQQATTTTTQSTSSSAISSWEAAKETVLNNKALWLYDSPDKNASNTNLIST
                     NEYMKDLMQDENGSYYSINIVTDDNGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK
                     "
     gene            complement(9189..9485)
                     /locus_tag="ACIZE9_002335"
     CDS             complement(9189..9485)
                     /locus_tag="ACIZE9_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094163.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHAGYRHSWERIN"
     gene            complement(9478..9771)
                     /locus_tag="ACIZE9_002336"
     CDS             complement(9478..9771)
                     /locus_tag="ACIZE9_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HGC6094164.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(9917..10468)
                     /locus_tag="ACIZE9_002337"
     CDS             complement(9917..10468)
                     /locus_tag="ACIZE9_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HGC6094165.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFPRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(10642..10941)
                     /locus_tag="ACIZE9_002338"
     CDS             complement(10642..10941)
                     /locus_tag="ACIZE9_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HGC6094166.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGMLPEDVT
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTNE"
     gene            complement(10968..11276)
                     /locus_tag="ACIZE9_002339"
     CDS             complement(10968..11276)
                     /locus_tag="ACIZE9_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGC6094167.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQFHLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEARKEYLISPKLRLKSVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            complement(11393..12352)
                     /locus_tag="ACIZE9_002340"
     CDS             complement(11393..12352)
                     /locus_tag="ACIZE9_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6094168.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLEVDTIVGVKHKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHLFK
                     SMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            12496..13272
                     /locus_tag="ACIZE9_002341"
     CDS             12496..13272
                     /locus_tag="ACIZE9_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6094169.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            complement(13370..14017)
                     /locus_tag="ACIZE9_002342"
     CDS             complement(13370..14017)
                     /locus_tag="ACIZE9_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6094170.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(14017..14847)
                     /locus_tag="ACIZE9_002343"
     CDS             complement(14017..14847)
                     /locus_tag="ACIZE9_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC6094171.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            complement(14847..15596)
                     /locus_tag="ACIZE9_002344"
     CDS             complement(14847..15596)
                     /locus_tag="ACIZE9_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGC6094172.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            complement(15610..16074)
                     /locus_tag="ACIZE9_002345"
     CDS             complement(15610..16074)
                     /locus_tag="ACIZE9_002345"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6094173.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            complement(16124..16585)
                     /locus_tag="ACIZE9_002346"
     CDS             complement(16124..16585)
                     /locus_tag="ACIZE9_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6094174.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            complement(16567..17541)
                     /locus_tag="ACIZE9_002347"
     CDS             complement(16567..17541)
                     /locus_tag="ACIZE9_002347"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGC6094175.1"
                     /translation="MRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAGQYLFD
                     KELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGAMTICL
                     SNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWETCLNEF
                     DKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFMEMQWIN
                     SNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVLDQADF
                     DLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
BASE COUNT         5413 a         3377 c         2581 g         6303 t
ORIGIN      
        1 tataataaac atttccttga ggtttccttt taatcccctt cggaaaatca ccttttgtaa
       61 aatcgctctt aaggaaatca tctaaattac cagttctggt ctttttacct ccagtattcc
      121 ctgatttttt aggtggtaca tgttctttag taagttcagt gtatttttca cataaaatac
      181 acttacccat ctttttcata tctatcccca ctctttttaa ttcttatata caattatatt
      241 tcaaatattc attaataaat atccctattt atgataagga cctccctaac tacttctcta
      301 acgatttcaa atcgctagag aagcgttagc gcccctctaa cgttgtttga tataacctag
      361 actagatcgt taacgtaaag ggtgttttta acacaaaaat agccgtatcc tttgttttgg
      421 atacggctat ttgatattgc tcattcaatt gttgtaccac ggcatgcgtg aatttcatcg
      481 taatttccaa catctcctta tggttaggat caaaggttat tttctctata aaggtacgat
      541 acaaggcttt gatttgcttc ttctcactct gggcaagaaa acgatccaaa ctagtcaata
      601 tccgttggac atctttgact tgaatcggct ctccttgttg aaagatccct aagatttcat
      661 tttctcgaat gtgcaactgt cgtcgttttt cagtcaattc gtctaagcgg tcttttaaca
      721 tcggaaacaa ttcaggacta tcttccaaag cagcttccca tttttcaatt ttagtcttca
      781 attcttcctt tcgttccagt aacaccacga gttcttgttc caatggttgg ctttgtcgca
      841 ctatttcttc atttaacgct gccaccaatc ggggaagaac ttctggtagc tgaacgatct
      901 cctttaatcg gtcggcgaca aatgtttccg cttgttcggc acgaatcgaa ttggcatgac
      961 acacacttgc tcctttattc cgaaagactg aacaagaata atatcgaatc cgtttctttg
     1021 tgccatcctt tagggtattt gtgacattac tcgctgccat cggtgcgcca cattctggac
     1081 aacgtaacaa gcctgtcaat acattttcac ctgtatggtt ccatttgggt tgttttcctt
     1141 ctaaagcaag gcgttcttgt actttttgat aatcttcttc cgaaataatc ggttcatggg
     1201 ttcctttcac taaaatcggt ctcggattct tccccttccg tcgtttggtt tcccaattga
     1261 tgtagcgcgc atattctaaa taccctgcat aaattttatt gcgtaagata tctttgactg
     1321 ccgtggtaga aaaagcattc tttttgactg tttgatatcc ttgacgattc aaaaaattgg
     1381 caatcgctcg ataccctgct ccgcctaaat attttgcata gatcagacga acaattttcg
     1441 cctcttctgg ttcaatgacc aattgttttt gaccattcgt gtcaatacca ctgacatagc
     1501 ctaaacgtcg gcctcctgca taacgctttt tatctttcac taagctttgc attgacattt
     1561 gaacattctc cgcaatttgg ttgcgttcaa attcaccgaa actcccaagg agttgtaaca
     1621 tcaatttacc tgtcgaagtg gtcacgtcaa attgttccga gatcgaatgt aatcctacgt
     1681 catatcgcaa taattcctcg actgtttgta agacatctaa catattgcgt ccgagacggg
     1741 tcaatttcca aatcactagt agatcaaaac gatggttccg agcatcgttc atcattcgtt
     1801 gataggcgaa ccgatttttt gtggatttcc cactgattcc ttcatcggca taaacttcta
     1861 ccacttcata gcccatccgt tcggcaaact gtcgtccatt ttgttcttgt gcttgaatac
     1921 tatgtccttc taaagcttgt tcttgtgtac tcacgcgaat atacaatgcg actcgtttgg
     1981 tttgtatcat ttccatagat cattcgttcc tttctaaaat attttgtgtc agttgtcgga
     2041 agtaaatccc acaaactgtt ttatcctttg ttacctcaat ccgacaaaca tagtcacata
     2101 ataattgtcg actagagagg tcttttagtt gaagccattc tttcactttt gcttcacact
     2161 gttggagtga aagaaacgaa gaagtagaca tcggcttttg aagagcttgc agttgttgct
     2221 tgagttcttc cagtgaacaa ttgccctctt caaatgcctt aatccattgt gcttcttgtt
     2281 tcttttgttg gattactttg cgtttttcat cttttcgctt ttcggctaat tgttgcgtta
     2341 attgggcaat caaggcttga tagacgcctt cgtattgaaa aaaagcctgt atcttttcca
     2401 atacttctga ctcaaccctt tctgcccgaa gaaaaattcc ttggcagctt cggtcggtac
     2461 aatgataata atgaagcgtc ttcgtcttct ttgtattcca ttgatacttc gaactcagat
     2521 gacgaccaca gaagggacac cgaatttttt gacgtaataa gtacagatac gtatcttttt
     2581 tagctgtaca ccttgattgg cgaatctctt gggcttgtaa aaaggttgct ttcgagagaa
     2641 tcggttcaaa ggttcctaga tacttcccca aagatcctcc tttgatttcg ccatagtaca
     2701 atggattttt taggatacta taaatatgat agggctgaaa aggacgttcg cggaagaaaa
     2761 gcttttgttg cgtcaatcgt tgacaaagct ttttgtagcc atattttttg gtcaaataaa
     2821 gttgaaaaat atagcgaaca atccttgctt cgtgtacttc ttgttggatt ttcccattca
     2881 ctaaacgata cccatatggt accgcagaag acaaatattg ccgttgttgc tttttatagg
     2941 aaagtccggc acgaacattc tcaataatga cgtttcgttg ttgttctgca aaagtgaaca
     3001 ataattgcac aaatagttta ttcgttgacg cgtgtgagaa agaagcagga agaggttcag
     3061 aaatcgaata cacttgaacc tgatgttgtt ggcacaactc aataaattct aaggctattt
     3121 tggcttgacg tgccaatcga tcataacgcc aaacatagat caccccctct tcttctgacg
     3181 cacaaaccca agctctaagc tgtcgaaaag ctggacgctc cgctttttcc cctgattctc
     3241 ctttgtctga aaatcgttgg ggaatttgtt catatttctc taaaacatac tctttcactg
     3301 catcatattg agcgtcatta ctaattttcg cttcttcata aacagacgtt cgatcataac
     3361 aagccacacg catgcttgat tcccctctct atgaatgaac taaataccat tttttcacga
     3421 ctcttctatt gaacgaacgt tgcacaaagt gattttctaa atatccttcg ttcttcaacg
     3481 cttgaagagt acccccgata gatccagcag atacccctct tatttcgaaa tccaagtaaa
     3541 ttggttttgt aaaaaaggct tgatttgaaa aatgttcttg aatatacaga agaacctctg
     3601 cttttagtgt cattttattt ttagtcatta gaattttcct ttctttcatg tttgattgaa
     3661 tgaagtaaat gaagcataga tcaagcttca tttacttccg tttgggtttg ctcgctatca
     3721 tacagataag taatcagttg ttttgctaaa tcaataagaa atatttccat aacatggtgc
     3781 ctcactttca tactttggtt tattctaaat tacaatcgaa aatacgattt gagtgaagaa
     3841 ggtaatagaa tctcgtatgt tggaagaact tgacgattca tgtgaatacg tttcgttctt
     3901 ctcccttttt ctgcacacat attacccgaa tcaagcaatt gcctaaaaag ataggttaga
     3961 tcctttactt gaaattctcg ccttaacaag tcctcaaacg ggataggaaa aatatttacc
     4021 ttaatatccc catttttttg aattgatact tttccccaaa tcgtactggg cgtatgtttg
     4081 ttgtcactgt ttgttaaaaa tttatggcta ttcatcacca acaatgtttt cactcggtca
     4141 aataccgttt gctcacttcc taaactagta tctacaatta actgttcgta cgaattaata
     4201 agcaccgtct gtatatgctc taatcgtaaa ggatagccca gtatatcttg aattaggagg
     4261 gctccactat aaatcaaagc tagattatta ccaatgcgtt gcttcaaaga atgttcaggt
     4321 aaaacagccc atagtttttt ttgagcttcg acaaaagttg cttcaatttt tgtaatccct
     4381 tgttcaaaga gtttcaaaag aaataacttt ataccccaac caaaagtatt agaagaaaga
     4441 cttttaactt tctctgcgtg attcgcatcc tttgtaaact tgatatcaga aaattcgata
     4501 tatcgaactt tcaaaccagt taatttctca ttgaaataat tttccaaacg ctcttcagaa
     4561 gaggtaaggg tcaaaacaga aaaagtctct tgtggcataa gctgacaatt agaatctaat
     4621 cttagccttt cttctcctga agctaattga tagatcaacg agctaaagtt attttgagtt
     4681 gctgctccta actcatctag tattagtgga acacctccct gattgtttga tgctagcttt
     4741 ataatggctt tattggtagc attcatattt ctaagaaccg tagttggatt tccaaataaa
     4801 gaggcaataa agtgtaacgt agtggtttta cccgttgtgc tcttgccctg taggttaatt
     4861 agtaaactca aaaaagtatt agccttcgta acgtttaaat agcctaacac aatagaagca
     4921 ataccaatcg accaagcaag ttctaagttc gttcctaaaa catacttatg aaccaatgcg
     4981 tcaaattccg cttctgtacc attagttgtt aattggtagc atgagttttt agttaataca
     5041 gaaggaattt cacgtccaaa agaatcttgt aactgaaaaa tcattgcttc attttctttt
     5101 ttccagccaa gagattcatg ttcaaaaaag attggagcat tctcccgttg aatctgtaaa
     5161 aagtcaacga cttcagcttc tcttctagct ttaatgatta agccatgttt tgctaattgt
     5221 ttaaaattat tagtttgtaa acatccacct tctatttcta tttcatccca acaatgatcg
     5281 acataatagg caagaacaag tgtaatgact ttttgttcga tatttttgcg tatttgctta
     5341 ataaacatcg gacaagcaac tttttcttct tgaccttctt tcaccaaaaa tactccttct
     5401 tgattcagtt taaactggtc aaaataatat tcttgattgg attctaatga ttctacagaa
     5461 ggatttacag gttttggcaa cggatatttt tttacaaagt cttgaatatc tttattttta
     5521 tccgaagcat gcagacaatg aaatcgaatc ttattatcag ccgtaacaga caaacaagaa
     5581 ccattagaat tattcgtgtg ttttcttaat ggacattcgt caaatataag taaggtaact
     5641 cctttatgat cgccctcttt tatggtataa gttaattcag gatagtgagc taaccattgt
     5701 ttatagtctg cttgaataaa aggtaacact tctctaaaag atggatggct ttttactcta
     5761 gaggttgaca tcatggaatt ttcttcaact atctgttcaa gaattttaaa acaattactt
     5821 ctatctatgt tatcgggaat agaaaggaaa ctagataaac gatgcggacg ctcttttgtg
     5881 gactttcctt tgaccgctgg tgtaccaact aatttgcata atcttgaagg attataaaca
     5941 gaagtatcaa tatcaacttc atcttctact ccaaatcttc ggtgaagtaa ttgaagaaaa
     6001 ttctgaatag taagaatcgt ctcgtgatta tttggttgtt catttatggg aagaaaaata
     6061 tggtagccat tcccactatc aacttttaca aatgattcta ttctcttttc tttcaaataa
     6121 cgttctactt gttccataac attttctgcc tttttctttt cgctatctgt tgcacttccc
     6181 tctttccttt tagggtcaat atcaataaat acaaaccgaa ttttttcaat atcattgtct
     6241 ctcacagaat gctttttttg tgtaatcacc tcttgtttaa taggattata agttatgttt
     6301 actgtacctt cagacaattt ctgtttttct aaatagttaa taattgcttg agaatctgca
     6361 gtagaaaaaa tatgagaaac ggttttcttg tttaatgtag aaaaagttct caaattaaca
     6421 taagaaatcc ccagtgtatt taacagttgt aaatgcttct gaattgaagt gtgattcatt
     6481 ttcattaatt accactcact ttctaaaaaa tttttatttg tatgactaca ttacctccaa
     6541 cctctcataa tttcatgatc ttcagttcta caaaaatata tcccactcaa aatcttgaca
     6601 aaagaaaaaa gttgtgattt tggaaatcac aacttttttc ttttacgata aatcaatcct
     6661 tattaaatta tttaggaaaa tattgttcaa ttatttcttt atatattttc tcatagtatg
     6721 tttctgtcca tcctaatgtt cctataaaat caagtcctct acattttaaa ggttcactta
     6781 aactattaat atagttaata atgttgtcta tccttttctc tttatcttca ccttcaatct
     6841 ggggagcata tagtccaatt tcctcccaat aatatgaatc tctttcaatt cccatgatgg
     6901 tagctttggc taatttcaaa tcaaataacg attttagaat tcttagtgtc tcaataaagt
     6961 cttctctctt caactcttta atccattgtg aattttctgg attatctaaa atttcaagtt
     7021 catcttcatt ataagtatat ttcaaatttg acttgcttaa ctcatagata aatgaagttt
     7081 cttgactcat aattctttta agtacttgac tataagtttc gtttgacttt gcccatttcg
     7141 ctaattctac cactgtattc actaataaat cgaaataatg atgttctcgt tcaatagtct
     7201 cagcattttg aaaatgaaaa tcacctttat aaactccatt cttttccact gttttattaa
     7261 tattttttaa aaaccagaat gagtttgcaa atttagtcgt actttttcga ttaactaagt
     7321 taataactct tccatgtaat aataagacaa aaatacataa atttttagct tccttattat
     7381 tagatactaa ttgatcaatc atagggagcc attttttgat tttcactaat tgattgctca
     7441 taaatctttc actggacttt tgttcaatct taaattgcaa aacttctaac tcataattcc
     7501 catcttctga tttatttttg ggaacaacta tcaaactttt ataaagttta tccacatcaa
     7561 aatttatctt ttttgcataa tttgtagcca ttaatacatc tccttattca taataaattt
     7621 catatgacgc tcctctcaaa atttaccggt agactagaaa aaagaataaa agatacgtca
     7681 attcacactt tattcttaaa aaaaaactgg tctctctacc ggtaatatcg attgagtccg
     7741 cctttatcga ctttatcctt tttttatatt aaattttttc accggtagac agggagagaa
     7801 agaataaact aaaaagccct taattcttaa tgttttcacc tccttaccgt tcctaccgct
     7861 aaaatttaat ataactaaat tctataacat tagaagaaat tttaaatacc tttgataaaa
     7921 aatattgatg ttttttctct cattgtttac aaactagata gcttatgtat tcttattaaa
     7981 aataatagat atttcgaaca tcatcactct catctactta atttcgcatt tttactttat
     8041 aaaaaaactg attctaagaa aattaaataa tttttctcaa aatcagtttt tctttgataa
     8101 ataatatttt caattattta atcatttgaa aattgttagt cattccaata cgttgagaaa
     8161 ttcttccatc tgtataaaca cggaattgtt ttccaccagc cattgttgta tttccattat
     8221 catccgttac aatattaatt gaatagtagc ttccattttc atcttgcatt agatctttca
     8281 tatattcatt tgtgctaatt aaattagtat ttgatgcatt tttatcagga gaatcataca
     8341 accataaagc tttattattt agtacagttt ctttagcagc ttcccaactt gaaattgctg
     8401 agctacttgt agattgtgtc gttgtagttg ttgcttgttg agtagattct tctactactg
     8461 gagtttgagg agtttgtcca ttcacaatat caatgaaacc ttgttttaac tgttggttct
     8521 gagtttcatt gaagtacatg tagtttttat cattgccttg attttgttgc gttaaataaa
     8581 ctttaggttg tccattttga aagccaaaga aatatacatg ctgccctaaa tattctccag
     8641 tttctacatc agaataaact gctactaaat tgaaatctgc atgaccagtt ccatcttctg
     8701 accattgtac ggtaactggt gcttcattga ttgccatttt ccaatttcca tcaataactg
     8761 cacttggtaa aggcgtacca tacagactta cattgttctg aggattgtag cttttatatt
     8821 cttgacctaa tgtctttccc cattgtggga caaaaattgc tagttgagta gatttctcac
     8881 tatcccacaa agtattttta acctcttcag aagaagattc aatgattgaa ctttcacttg
     8941 tacttgcttc cacagattgt ttcatttctg ttgtagtttg ttcagttgat tgcgttttac
     9001 tttttttagc ctcaattgtt gtatcagttt ctacagtctc tttagtcctc gtattctcag
     9061 atgtacaacc agtgaataaa atccccattc caattagtaa taacaaccat tttttcattt
     9121 tatttccccc tttcaatttc tccctcgcgt acttatttta tcagtcaatt aatctcaatg
     9181 gtgttcattt agttaatcct ttcccaagaa tgtcgatagc cagcatgaca acgatctctt
     9241 ccttgagggc tttcagatgg attaaaacta gtagaaattt cccttccaca tcctctacag
     9301 cgataagttc tcattatttt tgggctatta gtattatttt tcttagttag agctatgagt
     9361 ccaactatga ttaccccaac tgtcttaatt acttttcctt tatctatatt cggatgcgca
     9421 agcatatatt tatataacca atatccaccg taaattaaac cacctaatac aatcagctta
     9481 gccatgtact cgtctccttt ctttttgttt aattactttt tgaatccatc ttgcagagaa
     9541 accataaact tctgtcaatt gacggatatc tacagttttt tcctgttcta tcatgttttc
     9601 gattcttttt ctaactaact cacgatcgta cattttcatt ggaaaagaaa tctgttgccc
     9661 tcgaaaagca agataaaatt gatagagcaa ttctgaatcc agttccattt cctcaaaaaa
     9721 gtcattcata cttttataag agttactcaa acaagtttca tcaatctcca tctacacacc
     9781 ccctgttatt ttttacataa tgaaaatagc atattactgg gtacattgat aattcatata
     9841 acatgtatca tcacatgtat ttttaaagtc aaaaagcatg taaaactact tataagtaac
     9901 ataagaaaat aaaatgttat ttttcttgaa ataataattg actatctgcc aattgccatt
     9961 cattacgaac atgaatactt agtgggtggg ataacttacc ttctgcattt atcaatactt
    10021 tggtcatctt tttttgtttc gcactcaatt gatcgtaaat ggtcttcgct tgttcataag
    10081 ccacttgact cgtcgctgta atcgaaccac aagcaaaaat aatggtgttg attttctttt
    10141 ctgtgaaaac agttgttaat atttccaaag attgttcatc atttccacga ggaaataccc
    10201 gaggactttt cgcttttgta tacgaaaaaa gattcacagc aataaaacca gtaaatccta
    10261 attgtcggat attcttttcg attaataaca tactcaaatc attcgtaaat ggttctgtat
    10321 ctgttggacg aatagtaatg actaccgcta atttatcttc cgcttctttt cctttgatcg
    10381 cccattgtcg tttgaaaaca tagcgatggg tatgatgagg atctcgccaa acttctgttt
    10441 gtgtggtcac taattctttt tcaatcatct ctttttctcc tatgctaatt tttgttcaag
    10501 caattcaatc accattgccg ttataagtgt caatactagt tgaaaatatt tcatattctt
    10561 tctccttttt tcttcagaat ttgatgaatc gctgtaagga tatcttctaa acatttcgca
    10621 atcattctca aataatcgat cttattcatt cgttcctcca atctgactcc aaaccaatcg
    10681 tccttctacc agtaacccac gaacaaattc tcgctggctg gtaatatctg taatgaaata
    10741 aactacatag tcttttccat cttctggtgc gcaataaata taaagatgtg tcatcactaa
    10801 acgtggtaga gtaacatctt caggaagcat acccatttca atttcctctt tttccatcgt
    10861 aacggattca tagccccact cttcaggagt agtgactagc tgtgcacact tttccagtac
    10921 ttcgatagcc gtttctaaca agtcctttcg ttcctttctt ttagatatca gtattcttct
    10981 ggtaataaca tcgtttgata ctcacccgaa tcaatgaccc atattttttg agacactgat
    11041 ttcaaacgaa gcttaggtga aatcagatac tcttttcttg cttctggttc ttcttgacga
    11101 tgaaccaact tttgatttcc tttttccgta gaaaattcaa agatttgaag atagtctaaa
    11161 tgaaattgct tttgaacgtt ttgatcgatt agattccaac ataaagcttg taattccacc
    11221 ggcaaactgt ccattactcc ctttgtgaca taacgttgtc ctttattttg aaacatttct
    11281 tttccctcct ttgccataaa aatagcccaa tcttctatta aagaagattg ggcttcatgg
    11341 atataatata tatttgatat tcaatttgat tcattttata ctatctgatt tgtcaaatta
    11401 agctagacaa tatgtcttta tctatgcagc tcaaaaatac ttccaatggt gttcgataat
    11461 ttaatgattt tcttggaata tggtttcttt tcgaggcaac ggattgaata aaggtttcat
    11521 ccgtgtccct aaagtccatt gttttaggta agccatctcg tctaagcaag ccgtttgagt
    11581 gctcatttag ccctctttgc gaaggtgttc ctggatctgc gaaaaagatg gcaatatcgt
    11641 tcgagttact tatagatcgc cagttggaaa attcttttcc acaatcaaat gtcatggatt
    11701 taaacaagtg tttaggcatg gatttgaacc aatcatttaa cctgttttcg atatcttcgg
    11761 ctcgtctgcc tgtcggtttc aaagtaataa taaccttgga taaacactca accaatgtaa
    11821 taacagcgct cttgtgttta actcccacaa tggtgtcgac ttcgagatga ccaaattctt
    11881 tagtcaggtg tggatagaga ctgttccgtt catgaatcgt tctgcgaaag gcctgttttc
    11941 cacgcttttc ttgatgatta ttcggtttac gtttcccctt cataggtaac gactgtgtgt
    12001 caaaaaggcc ttttttaaac atccgataga gtgtacgaac agaacaatca attggaaact
    12061 cgccacggcc gataatcaca tcgggtgacc atccttgagc taccttttct tgaacatatg
    12121 ttgattgttc atcagataaa acggttgaac gtcgtccaca acgagattta ttttgtttgt
    12181 attgacggta ataatctagc actttttttc cttgtttgag aaacgaataa acattataaa
    12241 tggtttgtct agagcgattt aaactttgtg cgacaagagc gacaggtttc tcgatattga
    12301 aataagactc tatgattact agttcgtctg ttgtaagatg ggtgtaagtc atttgtactc
    12361 actccttatt aattctttgg tcggaactat tttgagtgta gcacaaatga tctttttagt
    12421 tgtctagctt aattttacaa tcgacgtttt aataaattgt gatataatga agtataactt
    12481 tttagggagt gtactatgaa ttttcaagat aatagaccat tatatttaca agtagaagct
    12541 tctatacgta acgatattcg tgaaaaaaaa tatcttccag gagagcaatt acctacagaa
    12601 gaagaattat gtaaaattta tggagtaagt aagattacca ttcgaaaagc ttttaaactt
    12661 ttagcagaaa gtggaacagt tgaacgatta agggggaaag ggacctttgt aactcaaaaa
    12721 aaagaaagtt taaaattagc tggagttcat ggatttagcg attctctttc tacccgagga
    12781 cataaaatta gatatactgt tttacattct aaaattataa aggctgatga gtttttagct
    12841 aataaattac aaatcaatgt aactgataga gtttacaata ttaaacgttt aatgtgggaa
    12901 gacggtgccc cgatgggaat tgataatttt ttcgcatcag aagaaaaatt tccaacttta
    12961 tttgaaaaag gtagccaata tacttcatta tataaacttc tagaagatga ctatgatgtc
    13021 aaagctacga gctctattat ggaaataaac ggtttatctg caacacctga gctttccgac
    13081 ttattgcaat gtatagtagg agatccgcta tttattttag aaaaggttgg caaagataaa
    13141 aataatcaac catttcatta ttctcaatcc acagttcgtt gtgatagaat tagttatgtt
    13201 attgaagtca cagaaaatat cactttagat acggtgcata aaaatgattc agatcctaaa
    13261 gtaatagatt gatattaaaa gaaatcatac ccaaagcaat caattttgat tagatttggg
    13321 catgattttt atttttacta atattctcta aatacatcaa aaaacttatt tatattccaa
    13381 atttcacctg tacttcttgt cgcagatatt taatatcgta aataacatca tctgctagac
    13441 ttacatcttg agaaaaacgt ttatctttaa ttgcaagaac cttcatattt gctcttttac
    13501 cagcttttat accattataa gaatcttcta tcaccagaca ttcttcaact ggaattctga
    13561 gctgttctga agctttaagg aatatagtag gattaggttt actttctggc aaatctcttc
    13621 cgctaattaa acaatcaaaa tatgactcta ttttacaagt ggtaacaact tcatttatag
    13681 tatccattgg actggaagaa gcaattgcca tttttatttt tttctttttt aaccattcaa
    13741 gctgttcaat tagtatatta ggaaaaatat ccaagtaatc aatcttttgc gatttccaat
    13801 atttagtaaa ttttcccttc aattctaaac tgttacatcc ctcattgtac ttttctatat
    13861 catcaaaaat acttgctgta gttccaatct ttttttgata agaatacaaa ggatagctta
    13921 aattttcttg ttttaaaaaa ttaaataccc acttttgata cataatctcg ctatcaatta
    13981 aaactccgtc catatcaaaa attagagcct taatcattat aagataccta ttatacttaa
    14041 aacaaaccct gccaaaatac aacctaataa gagcatattt gtactaacat ttttcttaat
    14101 caatttatat attcccaaag tacatacaag tggtaataat ccaggaataa tggaatcaag
    14161 taagtcttgt aaaacaagtt ctgttccccc tgtagtgaat tttaaagggg tgacaattgg
    14221 caccatgcta gccaccattc cacctactac agccaaacca atgatagaag caaattgcat
    14281 tactcgatcc ataagacctt cttgatacaa tttagtaagg tatttattgc cagactcata
    14341 tcctaattta ccgccgtaaa aaacagctaa aatagaaggt atagcaaaaa ggccaacagc
    14401 taaaatcggt cctaaaatac taccttgctt agcaaaagac aatccaatcc caaatgtaat
    14461 aattcttaaa gtaccttgga aaaatgaatc accaattcca gcaaaaggac ccattaaact
    14521 ggttttaatc atggagatag attcagtatt aaagtttcct tcttctgctt gagcattttg
    14581 ttcttccata gaagcacaaa gtcccataat aaatgaagtc atttgaggcg tacagttaaa
    14641 aaatgccata tgacgagtat aagcttctct ttttttctct tcatcatttt tataaacttt
    14701 atttaaaatt ggcgccatcc catacataaa tcccatatgc atttgtcttt cataattcca
    14761 cgaacacatg attgtccatg aacgaagaca catcttatta agatcttttt ttgtgattaa
    14821 acgttttttt tctgtactat tttccattaa ccatgcgcct cttctctttt tccatattta
    14881 acttgatcca ttacaaaggc aatcagagct gcaaaaattg tcacgccaat tagtgaaaga
    14941 cctgaatagg caacaataaa gaatccaaaa ataaagtaag gatataattt tttactcaac
    15001 attgtgctta atagcattgc aaaccctaat gcggaaagca tatttccaga gacagtcaag
    15061 gcgtctgtaa tcatttctgg aattttatct actaaatctg ccacaacgtc agcaccaaaa
    15121 tatactgtta aaaagattgg aataaagtaa acaaaagcat taaaaataaa tgaccaataa
    15181 atatgaataa tttgagcttt tctaaattta ttattttcaa tggctttatc tgcagcatgt
    15241 ccaaattgag caattatcat gcgcatgata atactcataa attcaccagc tacagccact
    15301 gggatagcta ttgttaaggc tgtttctgta ctactattag ttaaaattgc aaaagcagtg
    15361 gcaataatac taccaagttg catattagga ggtccagccg ccccaattga gacgaatccc
    15421 atagaaatta attctaaaga tgccccaaga acaatccctg tatgcaagtc acctagcaca
    15481 agtccggcaa gtgtactcaa aattagtggt ctaccaatat tttgtcgacc aattaacctg
    15541 gagtcaataa cagctaccac accaactaaa cctaataaaa tggcttttaa taacatttat
    15601 tttcccccct tacttactaa aatctacatt ttcaatactt gaagatggga cttgttgcac
    15661 aaatattttc acttcttgat caagaatttt ttttgtggct tctaattctt caggagttaa
    15721 aaagactgcc tttccatatt gtttggactc gcttttctta gacacaccgc caaaattaat
    15781 ttctttaatt tctggtaaat tttgaactaa ttcaaaagct tccttaggtc ctttaattaa
    15841 aatcatgtaa ttatcatttg gggatgtttc cataatccct ttaacatcac taattttaac
    15901 aatgtctaat ttgcaatcag caggtttagc aattgtcaaa gccatcacag acattggatc
    15961 tcctggaact ttgttatcag ccacaataat atggttaata tcatactgtt tagtccaaga
    16021 aaatattact tgtccatgaa gtaatctgtg gtctacacgc actaatttaa tcattctatt
    16081 tcctccttca atttttaaaa tttatagaat agaaattgcc accttaactg acatctttta
    16141 aaagcgaatt aatatgaacc atactttttt gagagttatt cagtaattcc ttaaaatcta
    16201 tttcttctat agatttacca gctgactggg ccattaataa ctccagtaaa agaggtaaat
    16261 taatcccagc aataatttga attctattgt tgttcaactg tttaatagaa acattattag
    16321 gtgttcctcc aattaaatcc gttaaaataa ttagaggttg caaatgatgc tgactaatta
    16381 tttctttcat actctcctca aaatcatctg gactagtatt ttctttaaat ggaacagcac
    16441 taatacctgt ggcgtcattc attaaaatta attttgttgc ctttaaataa ccctcacaaa
    16501 gggtagaatg tgttgtaatc acaatgtgaa ataattgatt tgccatcttt tgcaacctcc
    16561 tattaattaa tatttcattt gccacatata gcgtctaaca tctaaggaat ggcctctttc
    16621 aaaagcaatc gcttctacca tttggcgaat aacaacgcca ctaagtacag ctgcaatata
    16681 ttctttcgct acactatcta tagattctaa gtcaaaatca gcttggtcta aaaccattaa
    16741 tttattactg aattttttag tgaagtcttc tacccgttga tctaaaaatc ttgtatctcc
    16801 aatacttttc actaagatga atggtacatc ataatcagtg atttcaaaag gaccatggaa
    16861 aaattcccca gaatgaatag cattagaatt aatccattgc atttccatga accagcaagc
    16921 tgctgtggag taaatttctc cgtaattgat accgctacca attgtgtaaa taattttatc
    16981 tcgtttttgg tttttacccc attctttagc agttatttca aatttgctct tttcagcaat
    17041 aacaagatca tttaacttat caaattcatt caagcaagtt tcccattttt tagagccatc
    17101 taaaacaagt aaaatattaa ataataaacc ataaagaatt cctttattta aatcactagc
    17161 atcaacatct ttaccccaat catagtgaac aggatattca gctgcttccc atagaggaga
    17221 tccttcttca ttagataaac aaatagtcat tgctccaaat tctcttgctt tttttgttgc
    17281 ttctacagtt tctggtgttg tgccagaatg ggaacaagtg ataactaaag aattttcaga
    17341 taatcctttt ggtatagcat agttaaattc gttagcagta taaacatgac aaggtacagt
    17401 taattcttta tcaaatagat attgaccagc cattaaaacg gcttgtgaac ccccacatgc
    17461 tgtaaaatat acatgatcaa ttgtcttttc ctttaacgct gccattgctg tttcaatctg
    17521 ttctttgtgt agttgtctca tttctttatc cctcactcta ataagtatta taaagtcata
    17581 taactttaca atacctatta tctatgaaat tgctttattt tgcaatacta tttttcaaaa
    17641 aaattttttt ataacaattt tatataataa aatg
//
LOCUS       DBBGSP010000058        17512 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000058 DBBGSP010000000
VERSION     DBBGSP010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17512
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.058"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            189..419
                     /locus_tag="ACIZE9_002348"
     CDS             189..419
                     /locus_tag="ACIZE9_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGC6094176.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            516..1817
                     /gene="murA"
                     /locus_tag="ACIZE9_002349"
     CDS             516..1817
                     /gene="murA"
                     /locus_tag="ACIZE9_002349"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGC6094177.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1830..2006
                     /locus_tag="ACIZE9_002350"
     CDS             1830..2006
                     /locus_tag="ACIZE9_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGC6094178.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2141..2437
                     /gene="yidD"
                     /locus_tag="ACIZE9_002351"
     CDS             2141..2437
                     /gene="yidD"
                     /locus_tag="ACIZE9_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGC6094179.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2622..3089
                     /locus_tag="ACIZE9_002352"
     CDS             2622..3089
                     /locus_tag="ACIZE9_002352"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6094180.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3174..4058
                     /locus_tag="ACIZE9_002353"
     CDS             3174..4058
                     /locus_tag="ACIZE9_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGC6094181.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4172..4408
                     /locus_tag="ACIZE9_002354"
     CDS             4172..4408
                     /locus_tag="ACIZE9_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGC6094182.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4496..4576
                     /locus_tag="ACIZE9_002355"
     tRNA            4496..4576
                     /locus_tag="ACIZE9_002355"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4530..4532,aa:Tyr,seq:gta)
     gene            4583..4654
                     /locus_tag="ACIZE9_002356"
     tRNA            4583..4654
                     /locus_tag="ACIZE9_002356"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4615..4617,aa:Gln,seq:ttg)
     gene            4779..4949
                     /locus_tag="ACIZE9_002357"
     CDS             4779..4949
                     /locus_tag="ACIZE9_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094183.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            5169..5876
                     /locus_tag="ACIZE9_002358"
     CDS             5169..5876
                     /locus_tag="ACIZE9_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6094184.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5935..6579)
                     /locus_tag="ACIZE9_002359"
     CDS             complement(5935..6579)
                     /locus_tag="ACIZE9_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGC6094185.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            6706..6993
                     /locus_tag="ACIZE9_002360"
     CDS             6706..6993
                     /locus_tag="ACIZE9_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094186.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7101..7421
                     /locus_tag="ACIZE9_002361"
     CDS             7101..7421
                     /locus_tag="ACIZE9_002361"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6094187.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            7502..8815
                     /locus_tag="ACIZE9_002362"
                     /pseudo
     CDS             7502..8815
                     /locus_tag="ACIZE9_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            8812..9531
                     /locus_tag="ACIZE9_002363"
     CDS             8812..9531
                     /locus_tag="ACIZE9_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGC6094188.1"
                     /translation="MRCSCCGKDIIQNLTFSEIIGVSKSRLPQTCSVCRAQFHLLEAK
                     GCAGCQKPIHLKYEETKKKANTSFVYCNDCQEWKKKYPAYDFQHRAFFTYDEKMQAWI
                     NRYKFMGDIRLAGTFAYKWTQIKKDYPAYIYCPIPLSEKRWLERGFNQVSEMLKAAKI
                     PFQMLLKREQHLLAQAKNTRKERLEMPQPFELAVPLSKIQHKKILIIDDVYTTGQTLF
                     HAADCLQNAQPKIIRTISLAR"
     gene            9659..10210
                     /gene="raiA"
                     /locus_tag="ACIZE9_002364"
     CDS             9659..10210
                     /gene="raiA"
                     /locus_tag="ACIZE9_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGC6094189.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10432..12966
                     /gene="secA"
                     /locus_tag="ACIZE9_002365"
     CDS             10432..12966
                     /gene="secA"
                     /locus_tag="ACIZE9_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGC6094190.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            13092..14193
                     /gene="prfB"
                     /locus_tag="ACIZE9_002366"
     CDS             join(13092..13163,13165..14193)
                     /gene="prfB"
                     /locus_tag="ACIZE9_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGC6094191.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14298..14984
                     /gene="ftsE"
                     /locus_tag="ACIZE9_002367"
     CDS             14298..14984
                     /gene="ftsE"
                     /locus_tag="ACIZE9_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGC6094192.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14977..15861
                     /gene="ftsX"
                     /locus_tag="ACIZE9_002368"
     CDS             14977..15861
                     /gene="ftsX"
                     /locus_tag="ACIZE9_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGC6094193.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            16013..17461
                     /gene="cls"
                     /locus_tag="ACIZE9_002369"
     CDS             16013..17461
                     /gene="cls"
                     /locus_tag="ACIZE9_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGC6094194.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEIAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYILQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
BASE COUNT         5856 a         2966 c         3800 g         4890 t
ORIGIN      
        1 atttggaata agggactgcg acaagacttt tgtctcagtc cctttttttg catattttta
       61 gcatttattt cctaaaaaat gtaaggggat tcctatattt ttaagtatac ttgtttttcc
      121 ttttatacat tttatggtat tatcatttta ttagttatta taaaacaatc gttagaaagg
      181 acgtcattat gcaagtatac ggaattgatg cggtgcttcg aatcgtgagt catttggcgt
      241 ttatctactt agccttctgg tctttacgtt cgttacgcat tgaaactttt ttcagaccaa
      301 tgcataatac gcaaattaga atggcaatcg tacttttttc aattttttta gggtacactg
      361 caagtaattt tttcttagaa gttatcgctt tatgccgaaa tcttttcgtt agcctgtaaa
      421 ttttaaaaaa aggtactatt ttaaaagcaa ggatgttata atagaaaaga ttttgagtaa
      481 gtgtatgctc attggaattt tttggaggga acaacatgga agagatcatc gtaagaggtg
      541 gcaatcaatt aaatggaaca gtaagaattg aaggagctaa aaatgctgtt ttgcctattt
      601 tagctgctag tttgttagca gaagaaggta ttacgacatt agacaacgtt ccgattcttt
      661 ctgatgtctt cactatgaat caagtgattc gtcacttaaa cgtagatgta gattttgatg
      721 aacaaaagaa tcaagtaaca atcgacgctt caagacaatt agaaatcgaa gcgccttatg
      781 agtatgttag tcaaatgcgt gcttcaatcg ttgtgatggg tccgctactt gccagaaatg
      841 gacatgcaaa agtagctatg cctggtggat gtgcgattgg taaacgacca atcgatttgc
      901 atttaaaagg atttcaagct ttaggagcaa aaattattca aaaaaacggc tatatcgaag
      961 caattgcgga tgaattgatc ggtaacacga tttatttaga tttccctagt gtaggtgcta
     1021 ctcaaaatat catgatggct gccgtaaaag caaaaggaac aaccatcatt gaaaacgtag
     1081 ctcgcgaacc agaaatcgtt gatttagcaa acattttgaa taaaatgggc gctcaagtct
     1141 atggagctgg tactgaaaca atgcgtattg aaggcgtgga tcatttacat gcagtcaacc
     1201 actcaatcgt acaagatcgt atcgaagcag gtacctttat ggttgctgct gcaatgacac
     1261 aaggcaatgt gctgattgca gatgctatct ctgaacataa ccgcccattg atttctaaat
     1321 tgatcgaaat gggtgcagaa atcattgaag aagaaggcgg agtccgtgtc atcggaccaa
     1381 aacatatctt acctacagat gtaaaaacga tgcctcatcc tggtttccct acagatatgc
     1441 aagctcaaat gacagctatc caattagttg cagaaggtac aagtgtagtg actgaaacag
     1501 tgtttgaaaa tcgtttccaa catttagaag agatgcgccg tatgaacgct catgtcaaaa
     1561 tcgacggaaa tgtagcaatc atggatggaa accatgaatt gcaaggtgca gaagtatatg
     1621 caacagactt gcgggcagca gcagcattag ttttagctgg cttgaaagca aatggaatca
     1681 cacgtgtgcg taacttgaat tatctagacc gtggatatta taatttccat atcaaactac
     1741 agcaattagg tgcagacgtt gaacgtgtag acatggatca aacttctgct gaaaaaacag
     1801 cacaaacgat tgcttaagga agtggctgaa tgagtaacca acgatatatc ttattaactt
     1861 tgataaagat tttaatggtg atcttattgc ttatccttct ttttgtggcc ggaacgatga
     1921 tcggatatgg tgtcatcggt ggcggcaatc catttaaagt atttcagcca agtttgtgga
     1981 ttcatattcg agactttttt cattgataaa taagaatcac agtggttcta gtcgatatga
     2041 agtgagccat gaagcagaac atgataaaag aaaacagaag ggaacgttga cgttagtcgc
     2101 gatccctttt tttagtaaaa gaaaagaagg aatctaattg atgaagaaga tattgattta
     2161 tttagttaga ggatatcagc gctttatttc gcctgcattt ccacctagct gccgttatta
     2221 cccaacctgt tccaattata tgataaaagc aattcaaacc catggcgcgc taaaagggac
     2281 ggtaatgggg actgcacgga tcttacgctg tcatcctttt gtcaaaggcg gtatcgatta
     2341 tgtaccattg acattccgat taacgcgaaa taagaaagat aaaaaagaac cagattataa
     2401 aaaggttgtg aaaaatacgg gtagcactga gcgataaaga aacaatttgg aaaatagctt
     2461 cttatatttt gcaaaattgt gagttattgc cgaagtgttg gattttgaac accgtcaaaa
     2521 aaaaggttgt gaaaaatacg gctagcactg agcgataaag aaaaagagga aatttattgt
     2581 caaagtaaca actccgcaac tacttatatg ggggacaaaa aatgatcgaa gaactaaaca
     2641 agaaagattt accatggtcc ttgttattag atgcagatcc tgataaagaa aaagttcaag
     2701 tatatgtttc cagagggagt ggctggatat ggaaagaaaa agaaaaaaca ataggtgtac
     2761 tgatctatgt ggcaagggaa aaagaatacg aaatcgtcaa tgtagcagta accccaacgt
     2821 atcaaggaaa ggggattggc ggaaaattac ttgagacagc ttttcagaag ctttcacaac
     2881 tcgcttccag tcaaactcag atcatcatac gaaccggcag tactagcagt gcggcgttac
     2941 atctctatca aaaaatgggc tatgtggaga ttggtcgagt caaagactat tttatccatc
     3001 attactctga gcccattttt gaaaatggag atcaattaag ggatcaagtg attttagcaa
     3061 ttcacttacc taaaaatagc tttaactaat aaaatttcaa ttcaagaaaa tgctttcaaa
     3121 tgctaaatag atacattaca atagctttag caaacaaaaa ggagaatatt tttatgggaa
     3181 tattagtttt tgattttggt ggatcggctg tcaaatatgg ttgttgggat ggcaaagaga
     3241 ttaaaggtaa gggacaattt gcaacgcctg aatcttggga agaaatgaaa gcgcaattat
     3301 ttcaagttta taaaaaaata ctcgtttctt ttgaagtcga aggaattgga atcagctctc
     3361 ctggagtagt gaataatgag aaacaggtga ttgagggaat cagtgcgatt ccttatattc
     3421 atggatttaa tattttccga gatttggaaa ctctgtttca acttccagta acgattgaaa
     3481 atgacgccaa ctgtgccgga atggctgaat tttatgaagg tgctgcccgc gattatcaag
     3541 atgttgcttt tgttgtggca ggaactggga ttggcggggc gttgttcacg aaaggacaaa
     3601 tcaataaagg ggcacatctt tacggtggag aatttgggtt gatgttctta aatggcgata
     3661 agacattcag taaacttggt acagcggtac agatggcttg gcgttattgt gaacgcaaag
     3721 gtctcgataa aaatgcttat accggaaaag atgtctttga attagcagaa actggagatg
     3781 caatagcaaa agaagaagtt gagagttttt atacgtatct tacaaaggga ttattcagta
     3841 ttcaattttc gtttgatcca gaagtgatcg tattaggcgg cggggtttct gcaaaagaag
     3901 ggctcattga tgagatcaaa agccgaatga agaagctgac agaacaattc gatctgcatg
     3961 atttcgaacc gcagatttta ttatgtgaat acagaaacga tgctaatctt gtaggtgcag
     4021 cagcaaacta tctcgctgta cgtcaagggg agaattaaga gctttagaga aggtgcagct
     4081 tgcataaaag aagtgaatga aatgaatagg agatttttac ctaaggaatg ttttatttgc
     4141 tgcagtatga taaaatatct gagaggtgaa aatgatgtca aaaaaaaata aagatattga
     4201 agtgcgtata gaagaagtga aaaaagatat caaaggtaag aattatgaag tcactcagtt
     4261 atttataggg aaaaaaatga ttggtgagat cttagcctat ggaccaaaag aatatgaaat
     4321 tttctttggt gaagaagatt ttggaaaaga aaaaagtctt gaaaatgcga tagaaacagt
     4381 gattcgacac tggaatctgc acgaataaaa aaatatcaaa aaaactttca ataaagggtt
     4441 gcaaaaatct ggaaaattag gtattataac taagtcaggt tgatacaaac ctttcggagg
     4501 agtagcgaag tggctaaacg cgacggactg taaatccgtt ccttagggtt cagtggttcg
     4561 aatccactct cctccatttc attggggtat agccaagcgg taaggcaagg gactttgact
     4621 ccctcatgcg ttggttcgaa tccagctacc ccagtatacc acaatcgtaa gctctcgtta
     4681 gttcgagagc tctttttttt gctttgctac cttgttcctt gaagattctg ctgatttaag
     4741 atagagttaa gttaactaca agaattggag ggatccacat gaaatggaaa gaaaaagtag
     4801 acgaagcagc tgaaaagtta tatgatttgg tcaaatcaga aaaatacaat attgaagtga
     4861 atattccgaa aaaaggcgga aaagcggtcc gggtaaaatc aaaacgccca acgaatcata
     4921 caaaaaaatg gatggctaaa aaccgctaat aataacaaaa gatccataag tcggcatttt
     4981 catcgatttt agggtctttt gttattttct aggttggaca tatctaaaaa attgtttctg
     5041 acaataggag taggaagaac gatgtgtgtc taaatcctct gttgatggat agaaaccttt
     5101 atctttttca gttgtgaatc aggtatatac cagttataat agaagaaacg aaaggacggg
     5161 tgtacgttat gtcgaatcaa ttacctgtat atatacagat tcatgaccaa ttaaaaaatg
     5221 aaatcgaaca aggtatatgg aaagtcggag accgtcttcc ttcagaaaga gaattagcag
     5281 tgaaattcaa tgtcagccgt atgacgttga gacaagcaat tcaaaacttg gcagatgaag
     5341 gaatcttaga aagaaagatc ggttcgggta catatgttgc acgagaaaaa gtacaagaaa
     5401 aaatgtctgg tgcaacaagt tttacagaaa ttatggaatc acaaaatcga gtaccgtcta
     5461 gtcggacaat ctcttatttc ttgacttcgc caagctcaag tgaaatggaa aaactaaact
     5521 tgagtaaaga tgacacgatc ttgcgaatgg aacgtattcg tttcgcagat gatgtcccta
     5581 tttgttttga agttgccagt gtgccacaaa agctgatcga tggctacagc aaagcagaga
     5641 ttactgaatc gttgtatcgc acgctagaag aaaaaggcgg gaaaaagatc ggtccagcga
     5701 atcaaacgat tactgctgtg ttggcttctg agaaaattgc tgactattta gaggtaaaac
     5761 gaagagatgc agttcttcgt ttgcgccaga tttcttattt tgaagacggt acgccgtttg
     5821 agtatgtgcg tacgcaatac gtaggaaatc gttttgagtt ttatttggaa aaataaaaaa
     5881 caggtgatcc ctgattcctt attagaaata aaagagaatc agaatcacct gtttttatat
     5941 atgatcagtt atcagttgct cgtgataaga aacagaaccc tcttcaaatt ggacttgtcc
     6001 gttcagcagc tcaatgatgg attctttaaa gtggttagca cttttttcat ctacagcaca
     6061 gatgacgcta acttgatcag tatattggat ttcttttata aaaaaatgtt ggagttcaag
     6121 ataattctgt aattttccta gttgcggata cgtgatcatc acagagatct cctgttgcaa
     6181 ggtaccttct acgattccaa tgtcagacaa tgcttgagag accgcatgag tgtatgctcg
     6241 tattaatccg cctgtgccga gtttcgttcc tccaaaatat cgagtgacta ctgcagctac
     6301 attgatcagt tgattttttt tgaggacttc caacatcggt acgcccgccg ttccacttgg
     6361 ttctccatca tcgctgcttc gctggatttc atttttttct ccaatgatga aggcgctgca
     6421 gttatggttc gctttccaat gttctttttt tatttcttga atgaaatttt ttgcttggtc
     6481 ctctgattct attcgtctaa gagaacagat aaagcgtgat tttttgatct caatctcact
     6541 ttgtccattt tcttttattg tacgatagcg ctcgatcatc ttgtcacctc tttttttcat
     6601 tttctttatt cagtataaat aaagttctag gttgtttcaa cactgtaacg gttgcgcaat
     6661 tgctgtagta tgcgataata aagacaaagg caggtggatc tggggatgca ggaacgaatg
     6721 aaaaagtacg atgcaattac gcattatttg aagaacaatg gcggctctca agtaacgttg
     6781 acctttaccc aatttgacga actgctgttt cccagtaacg gacttcccaa aacagcaagg
     6841 gaaagtacag attggtgggc aaatgattat aaacaccctg aaaaaggtgc ctatggctgg
     6901 ataaatgcag gctatgaagt agttgtcatc aatttggaca aagaatatgt cgtgttcaat
     6961 aaattagtga aatctagttg gctatttgat taaataaacc gcgtttagaa aacgttgaca
     7021 aatttctttc tttttatata ataaagtaac agacgcgaag aaaacgtttg cgtagtttgt
     7081 tttaaaaagg agagaaaaat atggctaaaa aaacaatcat gcttgtatgt tcggctggta
     7141 tgagcacaag tttactagta acaaaaatgc aaaaagctgc tgaagcaaaa ggaatcgact
     7201 ctgatatttt cgctgtgtcc gcttctgacg cagataacaa tcttgcaaat aaagacgtgg
     7261 atgtgttgtt attaggccca caagttcgct ttatgaaagc tgattttgag aaacgtctgg
     7321 aaccaaaagg cattccttta gatgtcatca atatggctga ttatggtatg atgaatggcg
     7381 aaaaagtgtt agatcaagca atcgcgctca taggtgaata aatagaacag tataactatc
     7441 gaacaagcga tccaaaaaat agatcgcttg ttttttcgta tattttttta gggcgaataa
     7501 tatgaatcat ttttggggta gaaggcttct gacgagagat attaaagcaa tagactgtga
     7561 ggaggtaaat ttaccaaatt atgagaagat cgcagcagtg gaacgtttgg gcaactggat
     7621 tctttgtcat cgctgtggaa tgaggacgtc cgtcattgtt ggacagcttg cagattacgg
     7681 ttatttttgt acacattgtc tatatttagg gtgatgcgac actcaacaag atttatattt
     7741 gtttgatcag cctgaagcaa aacctcgaga agtcgtcttt ttttggacag gacagcttac
     7801 tgaaaaacaa acggaaatcg caaagagaat actttgccat tcagaaaaaa gacatcatct
     7861 tatttgggct gtaacaggtg cagggaaaac agagatgctt tatcctattt tagtggaaac
     7921 tttaaaagct ggaggaagag tagcgatttg tacaccgcga gtcgatgttt gtaatgaatt
     7981 gtttttacgc tatcgttatg tttttccaga agaaaaaatc acgttgctcc atgggaatac
     8041 agcaacggct tataccttta cttcttttgt tatctgtacg attcatcagc tataccgttt
     8101 ttatcggtcc tttgatttaa tagtgatcga tgagatcgat gcgtttcctt ataacgggga
     8161 tgctgggcta gctcacgctg tgcaaacagc aatcagatca aacggccgat tcatctactt
     8221 aagtgccacg cctgatgaga agttactaaa ggaaatcaag cagacatttg agctccacaa
     8281 acttgccttg cgctttcatc ggcgcttgct tcctgaaccc gtgcttgttt tcatgaataa
     8341 ttggcgacaa aaatgtggaa acaaaaagaa aatcaactct ttggtgcgga tcattcagca
     8401 actaatcaaa gaaaaccgta tccttttatt ttgtccaagt attacgatga tgcatcgttt
     8461 aaaaatcaca ctgcaagaag cttttccaga atatgagata acagatgttt cttcacaaga
     8521 cgatcaacgg gcaaagaaag ttcagaaaat gcgagaagca atatacgaga tactgttaac
     8581 cacaatgatc ctagaaagag gagtcacatt tgaaagaatc tctgtcatcg ttttaggagc
     8641 agatcatcca gtttttacta aatcctcttt ggtgcaaatc gcaggaagag ctgatcgtaa
     8701 aggtccttat acgaacagtc gagtctattt tttctatgaa gaaaaaactt cagctattcg
     8761 aaaagcctgt caggaaatca aagaaatgaa cgaagaaggg aagcagatgc tgtgagatgt
     8821 agttgctgcg gtaaagacat cattcaaaat ttaacattca gcgagatcat cggagtgtcg
     8881 aaatctagac ttcctcagac atgttcagtt tgccgcgcac aattccattt attagaagca
     8941 aaaggttgtg caggttgtca aaaaccaatc catttgaaat acgaggagac gaaaaagaaa
     9001 gcaaatacta gtttcgttta ctgcaacgac tgtcaagaat ggaagaagaa atatcctgca
     9061 tatgattttc aacaccgcgc cttttttacg tacgatgaaa agatgcaggc ttggatcaat
     9121 cggtacaagt ttatgggaga tatccgatta gcagggactt ttgcatataa atggactcag
     9181 ataaaaaaag attacccggc atatatttat tgtccaatac ctttatctga aaaaaggtgg
     9241 ctagaaagag gattcaatca agtaagcgag atgttgaaag cagcaaaaat tccttttcag
     9301 atgctgctca aaagagagca acatctgctt gctcaagcaa aaaacacgcg aaaggaaaga
     9361 ttggagatgc ctcagccttt tgagcttgcc gtacctcttt ctaagataca acataaaaaa
     9421 atattgatta ttgacgatgt ctatacaaca ggacagacgc tttttcatgc agcagattgc
     9481 ttgcagaacg cacagccgaa aatcatccga accatttctt tggcaagatg aatcagatgt
     9541 ggaaatttga tagcgattta atttgcaaat aacctagagt tcgatataat agaattaaga
     9601 agagggaaag agtggtcctt ctccttcttg attgtggtag acgaaagggg taatttttat
     9661 gtttagatat aatgtacgcg gcgaaaatat cgaagtaact gaagcgattc gcgactacgt
     9721 tgagaaaaaa gtaggcaaac tagaacgcta tttcagtgac gcacccgatg caacggcgca
     9781 tgtgaactta aaagtttata cagaaaaaac agcaaaagtg gaagtaacga tcccattacc
     9841 ttatcttgta ttacgtgccg aagaaacttc tccagattta tacgcaagta tcgatttggt
     9901 tgttgacaaa ttggaacgcc aaatccgcaa attcaaaaca aaaattaatc gtaaatcccg
     9961 tgaaacgggc atgaatactg cagatgctgc tgctttattc aatgaagagg acgaaaacga
    10021 aaatgattct gaattagata tcgtacgtac gaaacgcctt tcattgaaac caatggatag
    10081 tgaagaagca gtcttacaaa tgaacatgct gggacataac ttctttattt ttgaagatgc
    10141 agaaacaaat ggtacaagta tcgtttaccg ccgtaaagat ggaaaatacg gactgattga
    10201 aacagactga tcagccttac ttaaataaca acgaaaactt gcagcagcta ctgacagctg
    10261 ccgcaagttt ttttgagttt cctcctcttt tagatgaaat atgaataaat tatgaagttc
    10321 ttactttaat acgcttaaga tatttcaatt atctataact aatgataaaa tgaaaagtaa
    10381 agtctacata gtctggataa tacacagaag gaaaaggaga ttacacaacg catggccaat
    10441 ttgattcgtt cacttatcga aaacgataag aaagaactaa aacgtttaga tagcattgca
    10501 aaaaaagttg aagcatacgc tgaccaaatg gcagcattaa ctgatgaaca attacaggca
    10561 aaaactgctg aattcaaggg cagataccaa aaaggagaaa cattagatca attacttccg
    10621 gaagcttttg cagtcgtccg agaagcagca aaacgtgtat taggtttata tccataccac
    10681 gtacaattga tgggtggaat cgtgcttcac gatggaaata tccctgaaat gcgtactggt
    10741 gaaggtaaaa ccttgaccgc aacgatgcca gtatatctaa atgctctgac tggcgaaggg
    10801 gtacacgtag ttaccgtcaa tgaatattta gcaacccgtg actcgacgga aatgggcgaa
    10861 ctttataatt tcttaggatt aacagtgggg ttgaatatca actcaaaatc ttcggatgaa
    10921 aaacgcgagg cttataattg tgatatcact tatagtacga ataatgaatt aggatttgac
    10981 tacttgagag acaatatggt cgtttaccgc catcaaatgg tacaacgtcc gctgaattat
    11041 gccattgtcg atgaagttga ctcaatcttg attgatgaag cgagaacgcc gctgatcatt
    11101 tcagggcaag cagaaaaatc cacagcttta tatacaagag cagacaactt cgtgaaacgt
    11161 ttgaaagaag aagaagatta taaaatcgat gtacaatcaa aaacaatcag tttaaccgaa
    11221 gcagggatcg aaaaagcaga agaaacattc ggtttggata acttatacga cattgaaaat
    11281 actgcattga cccatcactt ggatcaagca ttgagagcca actatatcat gcttttagat
    11341 atcgattatg ttgtccaaga cggaaaagta ctgattgttg accagttcac tggtcggatc
    11401 atggatggac gccgttattc agatggactt caccaagcaa tcgaagctaa agaaggcgta
    11461 gagatcgaag acgaaacgaa aaccatggcg acgatcactt tccagaacta tttccgtatg
    11521 tacaagaaac ttgcgggaat gactggtaca gctaaaacag aagaagaaga attcagagaa
    11581 atttataaca tccaagtata ccagattccg acaaatcgtc cggttatccg tgatgatcgt
    11641 ccagatttgc tttacccaac attacaaagc aagttccacg ctgtcgtgca agatatcaaa
    11701 gatcgctacc gcaaaggtca acctgtgtta gtcggaactg ttgcggttga aacatctgag
    11761 ttattatcag atatgctgaa tcaagaacgt attcctcatg aagtgctgaa tgcgaaaaat
    11821 cactttaaag aagcagagat catcatgaat gctggtcaaa aaggtgctgt gacgattgct
    11881 accaacatgg ctggtcgggg aacagatatc aagttaggac ttggggtaag agaacttggt
    11941 ggtctagcag ttatcgggac agaacgacat gaatctcgtc gtatcgataa ccagcttcga
    12001 ggacgtgcag gacgtcaagg agaccctggt atgtcacagt tctacttgtc attggaagat
    12061 gatttgatga aacgattcgg ttcagaacga atcaaagctt tcttagatcg gatgaagatc
    12121 ggtgaggaag atgctgttat ccaaagcaag atgctgacga aacaagtaga atctgcacaa
    12181 aaacgtgtag aaggaaataa ctatgacaca cgtaaaaacg tcttacaata cgatgatgtg
    12241 atgcgtgaac aacgtgaagt aatctataaa cagcgacaag aagtaatcat ggaagaaaaa
    12301 agcttatcca agccactaat gaacatggtc aaacggacaa tcagtcgtgt agtagatgcg
    12361 catacacaat tagagaaaga aaattggaat ttggaaagta tcatcgattt tgccggcagt
    12421 actcttgtcc atgaagatag cattactctt gcagatatcg aaggaaaaac agctcaggag
    12481 atcaaagagt atctaaacga acgagcacaa gaagtattta ataccaaagc ggctcaacta
    12541 aatggtccag agcaactgtt ggaatttgaa aaagtcgtga tcttgcgtgt tgtggactct
    12601 aaatggacag accatattga tgcaatggat caattacgtc agtcaatcgg cttacgtgct
    12661 tatggacaga acaatccatt agtcgaatat caaacagaag gctataagat gtttgaagat
    12721 atggtaggcg ccatcgagta tgaagtcact cgaatcttta tgaaagctga gatccgtcaa
    12781 aacgtacagc gtgaacaggt ttctcaagga acagcttctc actcagaaga cggagatgcc
    12841 aaagaaaata gtaatactag cgcgaaaaaa cagccaatcc atgtgaataa ggtcggaaga
    12901 aatgatcctt gtccttgtgg aagcgggaaa aaatataaga actgtcatgg aaaaaatgca
    12961 aactaatttc tgacagcagg attggtgaga caaattcttt ttttaagaat tcgtctcacc
    13021 ttctttctgt tatttgctga ttctgttaga ctagatataa tgaaaaaagt atagtgaaag
    13081 aaggaaaaaa catggaaata tccgaaattc gaaatctcct gacagaaatg caggaaaagg
    13141 tcacaagttt caggaggtct ctttgactta gatcagctgg aagaagacat cgcggaagca
    13201 gaagcaaaaa tggctgaacc tggtttttgg gatgacagcg aagccgcaca aaaagtgatc
    13261 agcgaaaata acgctaataa agaaacctat gaccaattcc attctcttgc cgaagaacta
    13321 gaagaaatcg aattgatggt ggagatgctg caagaagaac ctgatgcagc aatgcaagaa
    13381 gaagcagaaa cacgtatcaa tgcattagat gaaaaaatga agacgtatga attatctatg
    13441 ctgttagacg gaccttatga tcgaaacaat gcgatcgtcg aattgcatcc aggggctggc
    13501 ggaacggagt cccaagactg gggcagcatg cttttacgta tgtatacacg ttgggcagag
    13561 cagcatggct atcaagtaga aacactagat tatcaagcag gtgatgaagc agggatcaag
    13621 agtgtgaccc tgctgattaa aggacataac gcttttggtt atctaaaatc agaaaaaggt
    13681 gttcatcgcc ttgtacggat ttcgcctttt gactcagcga aacgacgtca tacttctttt
    13741 tgttcggtag atgtgatgcc agagcttgat gaaacgatcg atatagaaat caatccagat
    13801 gatttgaaaa tcgatacgta ccgagcaagt ggtgcaggtg gtcagcacat caataaaaca
    13861 gaatctgctg tacggatcac tcacttgcct acaggaacag tagtagctag tcaggcacaa
    13921 cgctcacaat tgaaaaaccg tgagcaagcg atggggatgt taaaagctaa gctttatcaa
    13981 ttagaagtgg aaaagaaaga acaagaagca gctgcacttc gaggagaaca aaaagaaatc
    14041 ggctggggtt cacagatccg ttcttatgtt ttccatccct attctatggt aaaagaccat
    14101 cggacaaacg tagagacagg aaatgtccaa gcagttatgg acggtgacct tgatttattt
    14161 attgacggct atttaaaaat gcatctacaa taagaaccca ttgttaaatt gaaataaaat
    14221 tgtaagattt tgcaagcatg ttgaaacatt gccatgctat aatagctaaa gactgaaaaa
    14281 gatatggaga gaacgccatg attgaaatga aggatgtaat gaagaagtac tcaaatggta
    14341 cgaccgctat ccgcaatctc tcgattgtca tcgaacaagg agagtttgtc tatgtggttg
    14401 gtccgtctgg agccggtaaa tctacattca tcaaattgat gtatcgagaa gaaaaagctt
    14461 caaaaggaac tttgaacgtc gcaggtcatg atctaatagc aatcaaaaac cgcgaagttc
    14521 cttatctacg cagagaaatc ggcgtggtgt tccaagacta taaattatta ccaagaaaaa
    14581 cagtatatga aaatgttgcg tacgctatgc aagttatcgg cagaaaacct cgagatatca
    14641 aaaaacgagt aatggaagtg ctggaccttg ttggtttgaa acacaaagtt cgagtctttc
    14701 ctagcgaatt atccggtggg gaacagcaac gtgtctctat tgctcgggca atcgtgaata
    14761 cgcctaaagt acttatcgcg gatgaaccga caggaaatct ggatccagaa aactcatggg
    14821 aaatcatgaa attattagat cggatcaatg cccaaggaac tactgtcgtg atggctacac
    14881 ataacagtac gatcgtaaat acgattcggc accgagtaat tgctatcgaa aacggccgca
    14941 ttattcgaga tcaagcggaa ggggaatatg gatacgatga ttagaacctt tttccgccat
    15001 ttattagaaa gtatcaagag tttgaaacgt aacggctgga tgacagttgc ttcagtcagt
    15061 gcggtaacga tcacgttgac tttagtcggt gtattcatgg cagttatcat gaatgcaact
    15121 aaattagctc aggatataga aggaaacgtt gatgtatctg tattcgtaga tatcggtaca
    15181 aaagacgaag agatgaaaaa gctagaaaaa gaattgaatg acttagatca tgttaaaaaa
    15241 gttgaatttt caagtaaaga acaggaattg aaaaaaatcc aaaacgaaat gggtgattcc
    15301 tggaaattgt ttgaaggtga caataacccg ttatatgatg tgtatgtagt aagtgctact
    15361 gatccttctt atacaaaaca agtagcagaa gaagcagcag atttgaagaa tgtttctcgt
    15421 tctgattacg gtggagcttc ctcagatcgg attttccaaa tcgctggtgc agttcggaca
    15481 tggggattag ttgcagcggc attgctgctg ttcgtagcga tgtttctcat ttcgaacacg
    15541 attcggatca cgattttgtc tagacagcgt gaaattcaaa tcatgcgttt agtcggtgca
    15601 aaaaatggat atattcgctg gccgtttttc cttgaaggtg gctggatcgg tctgatcggt
    15661 gcgattcttc cgattttgat catcacattt ggttatgcat ggtttttcca attgatcaat
    15721 ccatcattat tacgttccca ttattcattg attcatccac aaaatatcgt ttggaaaatc
    15781 aatcttttaa tggtcggcat tggtgtgatc attggttcac ttggctcgat catttctatg
    15841 agacgtttct tgaaattcta ataccacaat ataaataaaa tgagaaagtt ggacagtttc
    15901 gttccagctt tcttttttta ttggctagga gaatagaagg aagcggcttt tttcccttta
    15961 ctttaaaaaa caacttgggt attcttaagt tggtagagga agaggtgaag ccgtgaaaat
    16021 tatcgttgac aattttttta cgatcctttt gattatgaat attttgcttt cctttatcat
    16081 cgtttttcga gaaagaaagg aaactgctca aacatgggca tggctgctcg ttttgatgtt
    16141 cattccagtt gtaggattta ttttatatat ttttttagga agagggattt ccaaagagaa
    16201 aatctttgat ttgaagatcc aagggaaaat cggtaagaac ctggaaattg aagaagacaa
    16261 acaggcattg atgcgagggc tttatcctca tccgcctact ggacaagtag atgtgaaaca
    16321 attgatctat atgctcacgg tatttgaaag tacgctctat acgactaaaa atgaaatcac
    16381 tttatttaca gatggtcgtg aaaaattcga tgcgctgatt gaagatatca agcaagcaga
    16441 agaccatatc cacttccagt attatattta tcgcagtgat gcattaggtg aagaagttcg
    16501 agatgcattg acagaggcgg caagacgagg ggtaaaagtc agagtccttc ttgatgcatg
    16561 gggttccaca caagtttctt ccagcttttt tcagaatttg aaaaaagcag gcggagaaat
    16621 cgcatttttc tttcctctat ttgttccgta tattaatcct cggatcaatt atcgcaatca
    16681 tcgtaaaatc gtagttattg atgggaaaat cggatataca ggtgggttca atgttggaaa
    16741 tgaatatcta ggattggtaa agaaatttgg ttattggcga gacaatcatt tgcgtattta
    16801 cggagaagcg gtgtatatct tgcaaaaccg ttttttgatg gactggaatt ctcagcatac
    16861 aaaagaagta ggctattctc ccaaattttt tccgtccatt cactctactg gtgatatagc
    16921 tgttcaaatc gtgacaagcg gaccagatac cgaacatgaa caaatcaaaa tgacttattt
    16981 gaaaatgatt tcgttagcca aacgggagat attgatccaa acgccttatt acataccgga
    17041 tggatcgatt catgaagcac tgaagttggc tcttctttca ggcgtaaaag ttcatatcca
    17101 aatacctaac aaaccagatc atcttctcgt ttactgggca acgtattctt tcgctgcaga
    17161 gctgatcgag tatggagcaa ggatcgaaac atatgagaat ggatttattc atgcaaagac
    17221 gatgattatc gatggtggca ttgtttcagt tggctcagca aatatcgatg ttcgttcatt
    17281 tcgcttggac tttgaggtca atacactgat ttatgatgaa cgaatggctt cacgtgtaag
    17341 aaaagcattt tttgaagact cgaaaatttc tacgcatctc acaaaagaaa tgtatgaaaa
    17401 ccgaggaata atcatcaaga tgaaagaagg attagcaaga ttgatttcgc cgctccttta
    17461 aaacacaaaa aggacatgag aaccatcaac agatggagat ctcgtgtcct tt
//
LOCUS       DBBGSP010000059        17501 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000059 DBBGSP010000000
VERSION     DBBGSP010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17501
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.059"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            104..454
                     /locus_tag="ACIZE9_002370"
     CDS             104..454
                     /locus_tag="ACIZE9_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGC6094195.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            553..1083
                     /locus_tag="ACIZE9_002371"
     CDS             553..1083
                     /locus_tag="ACIZE9_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HGC6094196.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            1237..2388
                     /locus_tag="ACIZE9_002372"
     CDS             1237..2388
                     /locus_tag="ACIZE9_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGC6094197.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVFLLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(2497..4536)
                     /locus_tag="ACIZE9_002373"
     CDS             complement(2497..4536)
                     /locus_tag="ACIZE9_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HGC6094198.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDQYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGEKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKDDDDSATKRASELLQYLNQNYQ"
     gene            complement(4594..5151)
                     /locus_tag="ACIZE9_002374"
                     /pseudo
     CDS             complement(4594..5151)
                     /locus_tag="ACIZE9_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     regulatory      complement(5299..5465)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            complement(5690..5896)
                     /locus_tag="ACIZE9_002375"
     CDS             complement(5690..5896)
                     /locus_tag="ACIZE9_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094199.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(5912..6526)
                     /locus_tag="ACIZE9_002376"
     CDS             complement(5912..6526)
                     /locus_tag="ACIZE9_002376"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HGC6094200.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(6673..7356)
                     /locus_tag="ACIZE9_002377"
     CDS             complement(6673..7356)
                     /locus_tag="ACIZE9_002377"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGC6094201.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(7465..7923)
                     /locus_tag="ACIZE9_002378"
     CDS             complement(7465..7923)
                     /locus_tag="ACIZE9_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGC6094202.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(8007..9770)
                     /locus_tag="ACIZE9_002379"
     CDS             complement(8007..9770)
                     /locus_tag="ACIZE9_002379"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HGC6094203.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(9991..11451)
                     /locus_tag="ACIZE9_002380"
     CDS             complement(9991..11451)
                     /locus_tag="ACIZE9_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094204.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(11659..12585)
                     /gene="glsA"
                     /locus_tag="ACIZE9_002381"
     CDS             complement(11659..12585)
                     /gene="glsA"
                     /locus_tag="ACIZE9_002381"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HGC6094205.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(12608..14035)
                     /locus_tag="ACIZE9_002382"
     CDS             complement(12608..14035)
                     /locus_tag="ACIZE9_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6094206.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(14066..15280)
                     /locus_tag="ACIZE9_002383"
     CDS             complement(14066..15280)
                     /locus_tag="ACIZE9_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HGC6094207.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(15366..15593)
                     /locus_tag="ACIZE9_002384"
     CDS             complement(15366..15593)
                     /locus_tag="ACIZE9_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094208.1"
                     /translation="MKNKFENRSDTRCGSFLYILYEVFFIPYEKISLKIKKDENKRFS
                     IKRRPFIFCLYLCEKRKRAQHIKLLLIVCLL"
     gene            complement(15621..15863)
                     /locus_tag="ACIZE9_002385"
     CDS             complement(15621..15863)
                     /locus_tag="ACIZE9_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGC6094209.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(15895..16452)
                     /locus_tag="ACIZE9_002386"
     CDS             complement(15895..16452)
                     /locus_tag="ACIZE9_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGC6094210.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(16465..16653)
                     /locus_tag="ACIZE9_002387"
     CDS             complement(16465..16653)
                     /locus_tag="ACIZE9_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGC6094211.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(16666..17232)
                     /gene="amaP"
                     /locus_tag="ACIZE9_002388"
     CDS             complement(16666..17232)
                     /gene="amaP"
                     /locus_tag="ACIZE9_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGC6094212.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         4984 a         3503 c         2972 g         6042 t
ORIGIN      
        1 tttgtcacaa tcctttttgt ttttttgaat aatcgctttt tcttctcttt ttcttatata
       61 ctataagtag taaataattt gaaaaaaaga aaggtgactg attatggcgc aaaatcgtat
      121 ttttacgaca agttttgcaa gcgtttatcc tatgtatgta gcaaaagcgg agagaaaaga
      181 tcgtataaaa gaggaagtag atgaaatcat ttgttggctg acgggttatt cccaaacaga
      241 actagaatat caactacaaa aacaagtgac tttcgaacaa ttttttgcgg aagcccctgt
      301 ccccaatcct tcacgttcct tgattacagg tgttgtttgt ggtgtacgag tagaagacat
      361 cgaggataac ttgatgaaag aaattcgtta tttagataaa atgatcgatg agctagcaaa
      421 aggcaaaaaa atggaaaaga tcctcagaag ttgatttttc cagagatatt cttctccttc
      481 gctcattttg taacatttaa tttggtaaaa tgactagttc acgttaaaat aagtcaaagg
      541 aggttttctt atatgtttga gacgattaaa caaaatattc aaaaatacgc cttattaaga
      601 gctgctgttt atattatttc tgggattgcg attgtgctaa acccttctgc tgtttttcat
      661 tttatcggtt atctgatcac cgcctatctt gttttgcttg ggttgttgaa tctttttgag
      721 gcttaccgtt ttaaaaggaa aacaggttct tggagtatcg gtctgttcag tggtcttttt
      781 ttcctgatct tagctctgat cgtctatgct tttgcacctg caatcgtttc tatcctgccg
      841 attcttcttg gattagctgt tatcatcaac agcttgttcc agttgttctt cagcatgaat
      901 acaaaagcta aaagttggag tgtttatagt agtattctgt tgttgattgg cggattcgtc
      961 ttattgttca atccattcaa aagtttgatg cttctattcc aaatattcgg ctttattttg
     1021 attttcatgg gcatccagga gattatcaat ttcatcagaa taagaaaaat gactatacgt
     1081 taatcatttt tagttattaa aatagaccgt ataaaaacca acaatccaaa aaaatctttt
     1141 ggattgttgg tttttttgtg agtatatttt cctatttttt caataatgta tgttatgcta
     1201 agttcgggct atattttata caaaggaatg atgagaatgg aatttattgg tattttatgc
     1261 ctgatattga tttcaacaac gattggctca catatctcgc ggagattagg tatcccagca
     1321 gtgattggac aattacttgt tggtgttttg ctaggccaag ctggattgaa ttgggtcaaa
     1381 cctgatattc tagtccatga cttttcggag attggtgtgt tcttattaat gtttttagct
     1441 ggtctggaaa gtgatttatc tcttttgaaa aaatatttcc gacctggtat gttcgttgct
     1501 ttgcttggga tcatcttccc ggttgttttt ggctggttga caggcaaagc attccaagtt
     1561 tcgggaaatg aagcgatttt ctttgggatt attcttgcgg caacttctgt cagtatttca
     1621 gtagaagtat taaaagaact aaacgtagtg aatacaaaag aaggatcaac aattttgggt
     1681 gcttctgtgg tagatgacat tttagtcgtt ttagttctaa gtttcagcct atcttttcta
     1741 acgggggaag cttctagcaa tgcttcttta ccgcttgttt tgattgaaca gctaatttat
     1801 tttgttttta ttttcttatt agtcaaatgg attgcgcctt tcctactttc atttgcagaa
     1861 aaagtgtacg caaattcttc tattatcatc gtatcgctag ttatttgttt aggaatgtct
     1921 tacgtagcgg atcttgttgg gcttagctct gtcattggtg ctttttttgc tgggatagct
     1981 gtcagtcaga caaaggttaa agaagaagta taccacaatg tagaggcttt aggatatgca
     2041 gtatttatac cagtattttt tgtcagtgta ggattagaag ttgatttttc tgactttagt
     2101 gaacaactac tctttatttc tatattgacg cttgtagcga ttttgaccaa attgcttgga
     2161 ggttattttg gtgctcagat tgccggtttt tctcaacata gttcattgat ggtcggtgct
     2221 ggtatgattt cgcgtggaga aatggctttg atcattttac aaattggaca gcaaagtcaa
     2281 ttgatcgaac cacagtacta ttcaccttta gttatcgtga ttttattaag tacacttatt
     2341 tctccacttg ttctcaaata ttttacaaaa aaagtttatg aagtgtgagt aaatcaaaaa
     2401 gaagttgtga aagagacatc gtgaaaaccg tttatttgaa aaaaggactg tgacgataac
     2461 gccacagtcc ttttactgta cttaaaaagc aattttttat tgataatttt ggttgaggta
     2521 ttgcaatagt tccgatgctc gtttggttgc tgaatcatca tcatctttat tttccaacat
     2581 gctgaccatc atataacctt ggttatcaag attgaaagca aacaagaaac tgttctcttg
     2641 cccctttaca tcctgttttt ctttgatttc cgctgtacca gttttcgctg ccaacggaat
     2701 ccctaaagca gaaagagaat gtgctgtacc atttacatct tgcacaactt ctctcagatc
     2761 tggcacgatc gtttgtactg ctgtttcgct gatgacattc ttcttatctt ttgtctcttt
     2821 atctgcaatc aatttaggat agacaagtgt gccattgttg gtaaaaacag aatacattgc
     2881 tgcttgctgg ataggagtaa ttagaagttc gccctgtcca tatccagtat cagctagcaa
     2941 gatatctgag ttaaagctat cttcattaga aatttgtgct ggattcatac taattggcaa
     3001 atcaaggtct tcaccaaaaa tgaatttatc taagcctgta cgaaattttt tctcacccat
     3061 tttcaacgtt tcttgtgccg catatatatt atcggaatag atcaaagcag tttttaagtc
     3121 tacttgtgat acatcactac tgacacgcgt tgttttaaaa gatccccaag aactgtcttt
     3181 ttgccattta agcccgttga tcgtcaacac ttcatttgga tcgatagtgc cgttgtcgag
     3241 accgattgct gctgtaatta ttttaaacgt agatccagga gcataacctg tcgcaaatcg
     3301 gctgatgaat ggatgttcag gattttcttc ataagctttg taatcttctt gtgagatccc
     3361 gtttgtcatt ttgtttggat catagcttgg agagctagca agcgcaagaa gatcaccggt
     3421 ttttggcgtt gtcgcaacag ttgatccagc ttttcctcct agactgtcaa aagctgtttt
     3481 ttgtgccttc gcatcgattg tcaatttgat atctttgcca ttttgaactt catgttcgat
     3541 cagaactttt ttctctacac cgtctgcatc tgtaatgctt aatttctcac ctgttgtccc
     3601 acgaagatcc ttatcaaaag ccatctccaa acctgagcga ccgatttttc cattactgct
     3661 taattctgga ttcttatcaa tatcttctgc tgtgatatct cccacgtaac caatcagctg
     3721 agcagctgct tcacccaaag gataatatct gccgtctact tcttgaatgg tagctccagc
     3781 tggaagttct ggcgttgctc catcaatgat tttcaatggg acaaagtaat cgggttgtac
     3841 ccagctttgt gaaatcgcct gattgatagc atcttctgtt aagtcgaagg aggaagcaat
     3901 cgctttgata ttggctgttt tttcgcctcc atctccaagt ttacttggaa cgactcctaa
     3961 ttgttttagt ttgcctgttg ttgctaatgg ttcaccattt cgatctataa tattccctct
     4021 tgctgcttct tgtgtggtca ggcttacttt gtcatttcct tccatttctg gaaaaaccaa
     4081 gttgggttgc cagttgatcg tggtttgacc atcatttctg tctaatgttc ctttataaga
     4141 aagatctttc aattcaccta atgaggtatt catctttgct ttatatgaaa aactgtaagt
     4201 agaatcgtct tttttatcta cttttagatt cgatatctga agtcctttga catcagcagc
     4261 accgtatata ttctggtatt gatctaagat ctctttttca gataatgcac ttttatttgc
     4321 cgcctttttt gatgtcattt ctgcagcttt gttataatct cccttgttca aagcttggac
     4381 aaattgctca actgtctttt ctccagcttc tactgcttgg gtttcttgat agtgctggta
     4441 gtaaaaataa ccgccacccg cagctgctat taagatcact gcgccggcaa tataagcgcc
     4501 tgttcgattt ttgccgtgct tgtcacttct tttcattttt tcctccttct cttgcttgtc
     4561 attcctttat ttcactattt atacctgttt attctaacat atgtctttga ggaaatccat
     4621 accacaatcc agaagcacac tttctggaag gttcgtttgg atactaccaa gtaatttccc
     4681 aaccgctttg ggtagcttga atattgaagt tacgtctttc agctgctgag agatagcttt
     4741 gatcacttgc tgctgccttc tgatcctccc gaagtctcct tctttgtctt cccgaaatcg
     4801 agcatactgg agtaaagtat taccatccat cacttgctct cctttgttta tatatacgcc
     4861 atctaaatct agagattttt ctgcatcgat cttgactcca ccaggaaaca gttcattaac
     4921 gcaatcgata aaatcttgaa atgtgatact tgcataatag ggagcttcaa atttgaaatt
     4981 ttcctttaat gtttgattta ataaatcaac tcccccataa gagtaagctg catttatctt
     5041 attcattccg taacctggaa tatcgacata tgaatctctc atgatagaga tcagttttgc
     5101 ttgttgtgtt ttctggttgt attgtgcaac cagaagtgaa tccgagcgac ctccaccaat
     5161 cgatcttttt tcaccgcatc tcctcctcac acagcaatcc acttgtcagg tgaggagcga
     5221 gtttgtctca tcaaataagt cagtcacaaa aatataaaga aaaggtcaga aaccttttcg
     5281 aacaagaatt ctgacctagc atcatctcat cgtccgagtt ttagcactat acaacgtaaa
     5341 gaaaacattc ttagctattg gaaaaagcct taatccaaca gtttctgttt tacccattgg
     5401 cgactttcga cgtttctggg caacagccta tgtttgtata ggagcctcac ctaacaaggt
     5461 tattactata ttctatttac gagttcatga tagacttttc ctaatgatta ggcaatggaa
     5521 tttgaaatga aatagtgaaa tttaacaatc tttaatattt tttagaaaaa aataacaaat
     5581 aagttgaaag aatcccgttg caaattcttt cagttgcacc aggattcttt gataattttt
     5641 tagttttatg tgttttttta tatgtttttt cacttttcgg aataaatatt tatttgttaa
     5701 agtaattaaa caatccgcta atcgtttgat ctggcatttc tatttcctta ccatctaaag
     5761 taacagtagt aacgacaaaa tggtcttgca atggcggaac ttctaagtac tgcccttgca
     5821 gaaaatcatt cactgtttca tattcttttt tcatttcttt tgaatctgtc gatggtttat
     5881 agcttatttt taacataact agtgctcctt tttattcggg acgtgcaatc gtgaaaattt
     5941 ctcctattgc tgcataatca tttcctgcca aacggcttac agcattcaat tttcttggat
     6001 cgatccttcc tgtcttatca tcatagactg tttcatttaa atgatatttc tgtacttcta
     6061 gcaaaaataa atcagctgtt actttatttt tattccgtat ctcgacatgt tcatataagg
     6121 atgtttcaaa acgaactttt gcttctgtca atgctggtac tgaaatgatt actgaatcag
     6181 ttaaagtcaa gtcagtcagg tacagttcgc tttcctcatt aggcagattg gctgctgttt
     6241 tatttacttc ttctacgttg tcctcatcaa ggatatggat aacagcttct cttgtctcaa
     6301 gaatattctt tgctgtgtct tttactgcat cttgttttct ctggatcgcc aaggataaga
     6361 tgggtcgatt cgaactgacg atattgaagt aactgaaggg tgcgatattc actatatctt
     6421 ttgctgattt agtcgttact actgctactg gtctagggat gactgaacca atcagcaact
     6481 tgtaattttc acgttctgtc aattctgaag gactccgttc aaacatggtt tcgccttctt
     6541 tctataaaat tcgttaaaaa gcagatcttg aagacaaaat gaaaagtaat gcttttttca
     6601 tcttcttaga atctgcttta aactatctat caatttttct tttttgtcaa gaatctgtgc
     6661 cgtgcgtgtt ttttagttat ttgctttact tgcggcttcg acatatcttt tagtgatcaa
     6721 ttgcggacgg gtgataatag atccaactac gactgaaaaa gcacctaatt catatgcttt
     6781 ctctacttgt tcaggagagt cagtatgtcc ttccataatt actgggatat cgacttgttc
     6841 tatgatttga ttcaataaat caaaatcagg tgtctgcgtc tttcgtgaat attctgtata
     6901 gcctgctaaa gtcgtagaca aaagatcaaa accatcttct tgcgcttgaa gcgcttcctc
     6961 aaaagtcgaa atatctgcca tagctaaccg accgtgttcg tgaatcattt ggacaagttc
     7021 agcagttgtt ttttctgtcg gacgtttacg agaagttgca tccagtgcaa tgatttctgc
     7081 ttgcgtctcc aaaagttctt ccacttcttt ttctgtcgca gtaataaaca cttctgaccc
     7141 atcgtaatct cttttgataa tccctattac cggtaaatca acgattcgct tgatttcatt
     7201 gatatcttct gtcgtatttg ctcgaatacc aactgctccg ccttcttttg cagccaaagc
     7261 cattctcccc ataataaaag aactgtgtag cggctcgttt tccaaagctt gacaagaaac
     7321 gacgactccg cctttgattt gttccagtgt atccacaata tctcctccag taatgttata
     7381 taaaaataca gcttcatata aaaatgtaac ccttttctat tcaggagaca ataatgagct
     7441 atttctttca gcagaccttt cttactaaaa gaaaattact tcaaattctt cgtatacgac
     7501 cagcttctct tctgtaaatt ctatgttcaa cgcttcttta taagcatgtt taaaaaactc
     7561 agcatggact ttccgccaat aagctaatgt ccgatcccct tctccttctt tccaagcatg
     7621 ctctttcgtg acttcactaa aaggcaagat ggtcacattt atatttttga tgatacaaac
     7681 tggttcattt tttccattca ggaccacgtc taattgacca acttttggta aaggctcatt
     7741 ctcttgttta tacagatcgt aaccacttga tgtaccagtc tttatctttt ttacaactag
     7801 ttcgctcaac tcgtctgcca ttttttctgt atccccaaat gaaaagaaac ctaatttttc
     7861 tgattgataa ctaggatatt tttcttggaa ctttttgaca tattcttcta cttgctgata
     7921 cataacatcc acccctttgc tttttataat gaaaaaacca tccagatact agtataaaca
     7981 attatctgga tggtgagcat aatgaattat tgaatattca agacacgcag actatcttca
     8041 acgatttgtt ttggtgttaa atgataacgt tcataaagct gccctacagg aacgctatcc
     8101 gtgaattctt tctctgcacc aaaatttaat acgttcattg aagaatcacc ataataacga
     8161 ctgatatttt cgccaaatcc tcctgacaaa ctaccatctt ctaatgtgat gactaattcg
     8221 tgtgtttctt ttaatttatc taatgtttct acgtcatttt ctgtgatcgt tcctggattg
     8281 atcaacgttg cttcgattcc tttttttcta aaagctttta ctgtttcttt tcctaattca
     8341 agaaaaccgc ctaaagctaa aattgctact tttcctccat tatttactgt ttgataggct
     8401 ggaatactat aatcatttgc gatagctgta ccatgttcta caccatgtgt aggaattcgg
     8461 attgctacag gctgcgctgt ttgttcgaac gcccaatcta gcatagagat catatcctct
     8521 tttgttgctg gagcaagata tttgatgttc gggatacttg ataagtaagg aatgtcaaat
     8581 gttccttggt gtgttcggtc actagctgag atcgttccgc caccgactaa aataatcact
     8641 ggattctcgt tgatcgctaa atcatgtgat aattgatcat atgcccgttg caagaaagta
     8701 cttgattgga agacgactgg acgtactccc tgagaagcca aagcagaagc gaaagtgata
     8761 gagtgctgtt cagcgatccc cacgtcaaaa taatgatctg gatgtttttc ttggaatgtt
     8821 ttcagtccaa aggcgcctgg tatcgctgca ttgactgcgg caataggagc tgtacttgtt
     8881 tgcattttct tatccaaata atccatgatg atcatattaa atgtttctcc agaagttact
     8941 tgctttgcct ccccggtgga cagatcaaat ggtacatgcc aatgatattt cattttatta
     9001 tcgattgccg gctgataacc gcgacctttt tccgtatgga cgtgaagtac aatcggatga
     9061 tcaatatctt ttacttcttc aaataaacgg atcaccgttt ccagatcgtt tccattatcc
     9121 acgtaacgat aatcaaatcc cattgcttta aataggttat tgctgctttt accgttggtt
     9181 tgacgaagct cagctaagtt tttatataaa ctgccatgat tctcatcaat agacatctca
     9241 ttatcgttta ctaatacgat tagattggat tgtaaaacac caccattgtt caatccttca
     9301 aaagctaagc caccacttag ggagccgtca ccgataaatg ctaccacatt tcctgattct
     9361 ttcttcagat ctctcgcttt agctaaacct gttgctaagc tgatagatgt agatgtgtgc
     9421 cccactgtaa aatagtcatg tttactttca tgttggttgg aatatccgct cacttcacgg
     9481 taatgtcctt tttcaaaacc attttttcga ccagttaaaa gcttatgacc ataagactga
     9541 tgggaaacat cccaaacgat tttatccttt ggtgaatcaa atacataatg aaacgcaatc
     9601 gttaattcta ctacacctag attcggacca acgtgcccac ctacatcgct gtccttttgc
     9661 aagatttttt ggcgcatctc ttctgccaac tgtttcattt cctcaacaga taattttttg
     9721 acatctgcgg ggctattgat tgcatccaat acatgtaata ctgtactcat aatacattct
     9781 ctcctccgta ctatcttctt ttaatgaaaa tagatttgtt acactttatc tattctacta
     9841 cttagagttg actctaagtc aatagcattt taaaaaaatt tcagagaaag cttgttatat
     9901 aagtagatct tcgcacgaat caggactcaa ataaaaacct tctacagaca attaaaaagc
     9961 tttgtagaag gtctcctaat taaggtctca tcaagaaata tgttttttta ataggtgaag
    10021 ttcctgagca atatgataca aatggatgtt tgcacctttt aatgagattg gatagatctt
    10081 tgtcttttca gtttctaatc cattttgata gctagcagca tcgcacaaaa ccactctttt
    10141 tttcgcacat agacattcat caggcaattc ttctaatgaa cgaaataaaa taggatttat
    10201 ttcagcgatg ccttcttccg catacaaatg aaattgggtt cgataaaaaa attgtttgac
    10261 tgaactttct gaaacaacaa aaatttctat ttcctgtctc cccgcttgtt cactgttgat
    10321 caaagaaaga cttttgacga attttcgaat gaaattttca ttccatctta gttggatttg
    10381 atttttcttt ttccactctt ccaatatttc tacaattttt ccgtacagaa gttgttcttt
    10441 ttctgataga agatagatcc tttccggtaa aaatacttgt ccatctgccc acaacgtacg
    10501 gacaaattgt aaaaaggatt gcttgaaaat aaaattttct gcatcgtcga tttcagcgat
    10561 actaataatc tgtaaaatca attcattcag tgataggtca ttgagaacaa aatttttata
    10621 aacaacttcg aaatcttttc ttaacagctc catgttctca ttggtataat ttctactgtt
    10681 gaacaaagaa aaaatataat agacatcttc ttcttgtaag tctagaattc ctttttgctc
    10741 ttccaatcct tgacagacta attgaaataa cggcttcgtt tctgcgcttt tcttatcttc
    10801 ttctttcagt ccaaggggaa atgcctttct tccgattgcg atctctattc ctcgtatgat
    10861 aaaggacttt tcatcttccg aatatcttct tttaaaaaaa tgagtctcta cataatcaat
    10921 caactcgtta caagcttctt ctacatacgg atttttattt tcatagcctt cccaattgac
    10981 ataacgtact aaagctagca agatgttccg cgagtcaaat tctgggataa tgatttcttt
    11041 atttttcaaa taatcatttt ctttaaaaaa atccaatacg atttttttga ttgtatatac
    11101 tttgctcaaa gaaataaatt caagatcagc cagttctgta ctcgtgaata taccattaaa
    11161 ataataactt aaaaacttta aaaaataaga ttgaccgtac agaaactgtg tgagctcaga
    11221 aagagcaata ccatgtttga atacgagttt atacttatgc ttctctctta cttgttcttt
    11281 tatacaatat tctagacact cggctagact ttctagatcg tgaaggatcg ttggtgtagt
    11341 cacccttaga gaaatagctg tttgttcgat gtctatttct tggaattcaa ataattgttc
    11401 acacagatac acttttctaa atatatttcg ctcgatgtaa ttttccagca ttcctgatac
    11461 acgcctccag tttttcttat gattttattt aatcatatct gtaaatcgta tttttgtttc
    11521 ctttttattt agaaaagccc tttcaaaaac caataaaaaa agaaactggg acaaaagtca
    11581 aacaagctca caatttcagc ctcattgtag gtagctttga gccgtttgga cttttacccc
    11641 agcctctttc aagaatggtt attcaaagat gtcagcgtct agttctttga ctacatcttt
    11701 caacaattgg ataccagctg cgctgttacc aaatggatct agtgccgggc tgaagacacc
    11761 tatgccgtaa cgatttggca cagctgccat caacccgccg cctacaccgc tttttgcagg
    11821 tacaccaaca tggacggaaa actctcctga ttcatcatac aaaccagcag ttgtcataat
    11881 tgatttgacg attgtagcac tttcttcagt aatgatttgt ttgccattcc aaggagcaat
    11941 tcctttattt gccagcacag cagctaattt tgctatgcct gtagcggtga cattgaggga
    12001 gcattgtctg aaataagcat cgagtatctc cggtacgtct ccttcgatca tttgattacc
    12061 tttcatatag taagcaagag agcgattgat atcacctgtt cttgattcag aatgatagat
    12121 ttcttcattc aatgtgatat taggatcatc acagatctct ttcataaatg acaagattcg
    12181 ctcaaatttt tcatctgcat ctttaccggc aatcaacgag gttgttgcaa tcgctcctgc
    12241 attaacaaaa ggattcattg gatgtttgcg atgattgatt tccatattca tgatagaatt
    12301 gaaggcaaaa ccggttggtt ccgtgttgat tgtttgaaag actttttcta ttccgttgtc
    12361 tttgattgct aataacaata cgggaacttt tgacatgctt tcgatggcaa agcgcacatc
    12421 ggcgtctcct ccctcaatca gttgttttgt atccaaatca taaatcgcca tacctaattg
    12481 tttgggatcc acttcagcta atgctggaat gtaatccgcc acttgtcctg tttgataata
    12541 gtggaaattt tttccaatca attgttctaa ttcttttact tccatttgaa taaccagctt
    12601 tcatttttta tttttctgca tgctggaatt tatgacggca tgcgtagatc gtaaatggaa
    12661 taactaagac gataagataa gaaacaatca gaatcgtttc ataaatccca tgctgtccag
    12721 ctgcgatact agcaggtgga acaaatgaga tacaaaaagc aaaaagtgaa gtcaaaagac
    12781 ctaaacaagc aacgattact tttacaactt ttccgcctgg aacctgatag gctctttcaa
    12841 gactgtcatc tttaaaaacc agcttcaaat agcccgcgaa aaacataaag tacaacatca
    12901 ggtagattac aacagtcaat gacatcgctg caagaaatga aagattattc cccccgccgc
    12961 ttaatgtaaa gacggctgcc cagattgttg caacgatccc atttgcgatc atcaaatgag
    13021 caggaacacc gtgtgtgttt tcttttgcaa aatattcagg aagtaatcct tcttctgctg
    13081 ctacgtgaag tgcttttgaa ggagaggtta cccaagaagc aatttctccg atgacaccta
    13141 aacaaacaag aatcgcaaga attttcgcaa tccatgcaag atttggatca atgtgtctta
    13201 ataggaattc taacgattga atcacccctg tattaagaga caaaccatgt tgaggtactg
    13261 tagtagcgac ggtcaatccg ccaaaagtat ctaaaatgat tgccagaata accaatacaa
    13321 acattgctaa tggataatcc tttttagggt tttccatttc atttgcatga ctggcagatg
    13381 tttctacgcc catatatgct aaaataaagg aaacaaaaac aaccagcgta ggcaatttcg
    13441 aaaaatcagg aatcaatgtt ttcatagaca gtatcgtttg tagtggagcg cctgaagcga
    13501 cataatggat ccctaagcca aacaagacta atgctggcaa caagatacca gctacaaaac
    13561 cgatccgagc aatcaatgaa gtgtatttgg ttccttttaa ctgtgagagt aaaatagccc
    13621 agaaaataat caataggatt gccaatttca gatatttatt gttttgtata gcaccaatac
    13681 ccgttgcata ggataatgca ccagttaaga aatacagcat ggtcaagtag ccaactgtta
    13741 tctcaaacca ttggaaaaag attgcggcaa aaccgaatcg ttttcccaat gtgcgactga
    13801 cccaagtata gacaccgcct ttttcccatc ctttcaccgt tgccatctct gctgcgcaca
    13861 atgccacagg gataaaccat agcaaaccgc ctaataacaa gaaaaatact aagctgaagc
    13921 ctgaggtcgc gaatgtggga tattcatata atgaaacgac cattgagatg gtcatagcca
    13981 aaaagccaaa gaacgttaat ttttttgcag gaattttcgt tttgctttgt tgcatgaatc
    14041 ttcctctttt ctatttgaat ttgtttcaat tgagtttgtt gccaaagaag aaaaagtcca
    14101 atccttcttc ttgttcttct tttgtagtag tgatcgttgt aaagtgcatc gccgatttta
    14161 aaatcactgt tgtcagcaca taggcataca cggcagtaat gatgacacca atcacttgaa
    14221 tccctaagaa gtaccagctg cttggattcg ttagtaaatg gctgttagat gcaaagatcc
    14281 ctatcagaat cgtacctgtg aatccgccca tgccatgaac accccacaca tcaagtgcat
    14341 catcccattg tttcttttta cgaaaatcaa cagcagcatg acagacgata cccgcaatga
    14401 tcccaatcag catggcactt tttgcttcta cataaccggc acaaggcgta atggctgcca
    14461 atccagcaac ggatcctgtt agtacgtcga caaaatcaaa gccatttcct tttacttttg
    14521 caatgatcag ccaagtaatc atcgcaaatg caagagcgat gaatgttgaa ccaaatgcat
    14581 tgactgcttg ttcatctgct cgaagtgcac caccggaatt aaaaccgaac cagccaaacc
    14641 aaagcagtcc tgtaccgata gcagctgcca taagactgct atgctgactt ctttctccta
    14701 aaggaatctt tctttgacca agtgtgagga tacatgctaa agagccgaat ccagctgtcg
    14761 tgtggatgac tgctccacca gcgaaatctc taaatcccat ctgatccaaa aatccgccac
    14821 cccatatcca gtggcaaaca gggaaataaa tcagcagatt ccaaaaaata acaagtataa
    14881 tatagccttt taaattcaat ctccctgcaa aagctcctgt catcaaagga acggtaatca
    14941 cgataaacat cagttggtaa agaaagaaca ttaaaaatgg aatcgttgca ccatgaaaca
    15001 tgttggggaa gcttgtaaca tgtctcatca aaaagaaatc tgccgggttt ccaataacac
    15061 cgccgatatc ccgtccaaag gccaatccga atccaccaaa tacccacata atcgttgtta
    15121 tcccaacgga gagaaaagat tgagacatga tcgttagtat attattcttc cgtgctaatc
    15181 cgccgtaaaa aaaagctaga ccaggagtca tcaggcaaac cattgctgta cataaaatca
    15241 tgaatgctgt atctcctgta ttgataggta atgtattcat ttttttcgcc tcctttctac
    15301 gattacgagt ataaaagaag gtgtagttgt ttttttcttc tgtttttttg aattaatact
    15361 tgcatttata aaagacagac aattaataaa agcttgatgt gttgtgctct ttttcgtttt
    15421 tcacacaaat aaagacaaaa aataaacggt cttcttttta tagaaaaccg tttattttcg
    15481 tcttttttta tttttaaaga tattttttca taaggaataa agaatacttc atataaaata
    15541 tataaaaaag aaccgcagcg agtgtcgcta cggttctcaa atttgttctt catttcaaca
    15601 taagtttttc ttcaatttgc ttataattta cgtgcaaaga atgaaacgac taatactaaa
    15661 atgattgcac cgatcaatga tggaatgata gccattcctg caattgttgg tccccaagtt
    15721 cctagtaaag cttgtccaat tgctgaacct actaaaccag caatgatgtt tgcgatgatc
    15781 cccattgatg atcctttatt cgtgattgct cctgcaattg ctccaatgat accgccgacg
    15841 attaatgccc aaataaatcc cattttaaat tcctcctaac tgacttctta cttcttattg
    15901 tacacgtggt tcgttatttt ctttgacttt ttgtgcacct ttgcctacag cagattttgc
    15961 tttatctgtt tggcgtgaag caaattgtcc tgtggatttt gctgcttctg ttactttgtc
    16021 ttgtactgtt tcttgatctt tttggtattc ttcttgtgtt ttgatgtctg caacattcac
    16081 attcacttcg ataacatcta aatgtgtcat attgtttact tcagtactga tcaattcttt
    16141 gatttggttg taaatatctt cgatgtcttt accgtattct acgatcacat ctagatccac
    16201 agctacttgt ttcttaccta cttctgtatt gatacctgct gttacgttat ctgtgttgac
    16261 taatttttca gccatatttg agaaaaatcc gccatctaat gtcaatagac catctacatc
    16321 tttcaatgca taaccgatga ttttttggat gactttgtct tcataagtca attcaccatt
    16381 catcatgcgg ttttctcctt tttcatttgc caaaactgat ccatttgttg tattcatgtt
    16441 tttgttttcc atctttgttt cctcctatga tttaaaaaat tgatcaacta ttcctgactg
    16501 tttcaaataa aaaccgattc ctgcgccaat tgctgtcatg attatgatca acaatgtctt
    16561 gaaaaatcca atcgttaacc ataaaacagc tagcagtagt ccaagacccc caaagataat
    16621 agggagcttg tatgctgaaa atagttcttt cattatttgg ccctcctatt ccactcgaga
    16681 gtgcttgtag tctcttgtat cttcttgttc ttcataaccg ctgtatgtga ctgccacttt
    16741 gaccgtttct tttgttccga gtactttagt tacttcttct tcgatatctt gcatcaatac
    16801 acctgttttc cctactaatg aagaagttcg tttcaagtct ccgttgacat ggatatggat
    16861 tcgatttttc gttgaacgta tccgtacttt aggtgaatga atgaactctt cttcgtgtaa
    16921 atgggaacgt accaaccctt cgatcgcttt tttgtcgatt gttagtttgc catcttcccg
    16981 tttcataacg aaagttcctc ttgactttgg atagaaaaga acgactagca agatgataat
    17041 agcaagaacg gcaaatacta cagctgccca gaaaatatat tgttgcatgt agtaattcgt
    17101 taaagtaaag aagcgaaatc gttccaattg ttcaggcata atatacggcg cattgatcaa
    17161 cgcaatcgct agaaatactg aaagtagcag taaactcatg ataacaccga ttatttttaa
    17221 ccccttattc attttccacc tcctataaac ttatttttac cctgtaaata actctaccga
    17281 caatcacagt atagatagcg aacagttagc atagcatcag taaataaagc gctaccaaac
    17341 attgctggat cataacggcg ttttattgcc agtctgatac tgaaataaca attgcttact
    17401 tattctctat ttacttttga ttgctggcta tacttaaagg atattattca agattaaaaa
    17461 ttgcaaagat tatgctcagt tattattaca agattctatt t
//
LOCUS       DBBGSP010000060        17006 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000060 DBBGSP010000000
VERSION     DBBGSP010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.060"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..125)
                     /locus_tag="ACIZE9_002389"
     CDS             complement(<1..125)
                     /locus_tag="ACIZE9_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HGC6094213.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(229..540)
                     /locus_tag="ACIZE9_002390"
     CDS             complement(229..540)
                     /locus_tag="ACIZE9_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGC6094214.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(542..739)
                     /locus_tag="ACIZE9_002391"
     CDS             complement(542..739)
                     /locus_tag="ACIZE9_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HGC6094215.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1133..2860)
                     /locus_tag="ACIZE9_002392"
     CDS             complement(1133..2860)
                     /locus_tag="ACIZE9_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HGC6094216.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2853..4046)
                     /locus_tag="ACIZE9_002393"
     CDS             complement(2853..4046)
                     /locus_tag="ACIZE9_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC6094217.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4233..4877)
                     /locus_tag="ACIZE9_002394"
     CDS             complement(4233..4877)
                     /locus_tag="ACIZE9_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6094218.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4971..5105)
                     /locus_tag="ACIZE9_002395"
     CDS             complement(4971..5105)
                     /locus_tag="ACIZE9_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HGC6094219.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="ACIZE9_002396"
     CDS             complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="ACIZE9_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HGC6094220.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7236..7709)
                     /locus_tag="ACIZE9_002397"
     CDS             complement(7236..7709)
                     /locus_tag="ACIZE9_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HGC6094221.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8110..8334
                     /gene="nrdH"
                     /locus_tag="ACIZE9_002398"
     CDS             8110..8334
                     /gene="nrdH"
                     /locus_tag="ACIZE9_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGC6094222.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8493..10652
                     /gene="nrdE"
                     /locus_tag="ACIZE9_002399"
     CDS             8493..10652
                     /gene="nrdE"
                     /locus_tag="ACIZE9_002399"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGC6094223.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10702..11667
                     /gene="nrdF"
                     /locus_tag="ACIZE9_002400"
     CDS             10702..11667
                     /gene="nrdF"
                     /locus_tag="ACIZE9_002400"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGC6094224.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11756..12895)
                     /locus_tag="ACIZE9_002401"
     CDS             complement(11756..12895)
                     /locus_tag="ACIZE9_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC6094225.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13204..13917)
                     /locus_tag="ACIZE9_002402"
     CDS             complement(13204..13917)
                     /locus_tag="ACIZE9_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGC6094226.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="ACIZE9_002403"
     CDS             complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="ACIZE9_002403"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGC6094227.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15106..16638
                     /locus_tag="ACIZE9_002404"
     CDS             15106..16638
                     /locus_tag="ACIZE9_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGC6094228.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16829..>17006)
                     /locus_tag="ACIZE9_002405"
     CDS             complement(16829..>17006)
                     /locus_tag="ACIZE9_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6094229.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2910 g         5323 t
ORIGIN      
        1 gaaaaaacac attccactaa atttgatgcc ggttttcctt gaggttttgt tccagcacct
       61 cctttaattt ttttaagctc ttgatctgaa cattgtttag catttagtct atttttttct
      121 tccattacga ttccccctac aaactataaa tacttttatg tcactgattc aatataccta
      181 tttttctaat caaaaaattt tgagacatat ttaatattat aagtatcatt aaaattgaga
      241 tttatctcca taatctgctc gatataaacc atttattcca gcagttcttc caatttcact
      301 caaatttctt attaattcct cttgatattc agtgaatctt attttattag tataagcagt
      361 aaaatataga taattcacca atctatttat taaaggactg ggatctaatt catatttttg
      421 tttttctaat tttaaatata ccttttgtaa aacctcaaga atatcagaat atttaggatc
      481 tttacttata gatatatcat tatataattc atgaacaatt tgcttagcat tttttttcat
      541 tttagcactt ccctggaatt gctccaccta aaaaaccacc tatagacatt cctgcaatac
      601 aagtagttgc cttggcccaa tcgaccgtac atttattttt agtgcaatac actccatttc
      661 cataatattt tccactatga gtggtacccc catagataag ttgtgtctct ttaatagaca
      721 aaatttttaa atgtttcata atctaatcac ccctaaatta atgtttttag actattattc
      781 taacattcat taaatttcaa aaaacaattc cttcttgaaa cgtagcaaaa taattcctga
      841 ataagaattt aatcactttt aagtatataa actatgtata ttctttaata ttttttgaga
      901 atgcacttcg tacataataa actttaatca cattagtctt tcatacctac gatcgatctc
      961 tttgactcgc acccataaat tcataatagt ttgtcggcgt ctttgaacgt ttcgaagatg
     1021 agctacgcat tctctttttt tatagacaaa aaagatagag acgaacatgg agcttccaaa
     1081 tttggatatt tgatccaatt ttggaagctc catttatttc gtgtctgtct ttttattttt
     1141 tccagctttc gactaattct tggttctctt tgatccagtc ttttgctgct tgctgtggat
     1201 cttttccatt gttgatttcc aacataactt tttccatatc tttttctgac caatggaaat
     1261 tgtctaatac tttgtaagct tctggctggt cttctttcaa tccttttcga accatcgtat
     1321 ggatctgctc ttcgcttccc attccgtttt caggatcttc taagtatttc agatcatatt
     1381 tggcaaacat ccaatgaggt gtccatcctg taactacaat tggttcgtgt tttttgatcg
     1441 cttgacctag tgcaacggtc attgctcctg aagaagatgt ctctactttc cagtctttca
     1501 agttgtcata tttttggatc gtgttttcag cagccgtaac tacaccagct cctggctcga
     1561 ttcctatgat tttcttacct gcctgatcgg ttaactcatc gatcgaattt acatccatgt
     1621 aggctggcac tgctaaacca acttttgctc ctgtcaaatt ggcacctagg tcttcgactt
     1681 gatctttata ttgtgcatat tgtgaaccat gagttttagg tagccaagct gaaaccatgg
     1741 catctgactc gccatttgaa acagatttcc acatgattga attatctaat ggcgtcatcg
     1801 ttacatcata gcccatttgt ttcaatactt caccgactac atttgttgaa gcaacttctg
     1861 tatcccattc aacataagat aagttgatac gttttgtttc tttggcagat gaaaaactcc
     1921 ctataccaat cgcacctaag atcactacta ctacagcacc aatgatcagt ccttgacgtt
     1981 ttttactttt ctgtgttgtt gctcctgcag cttttttatt gtttggctgg ttcaaatgct
     2041 gtgtaaaacg gtcaatgatg attgctaaga taactaatgc aaccccgttg acaaatccat
     2101 tcccgacttg tgctctttgc aatgctgata atacgccgcg tcctaagccg ggtgcaccga
     2161 tcatagaggc aataacgacc attgaaagtg acagcattgt tgtttgattg atccctgcca
     2221 tgatcgtact tttagctaaa ggcaattcta gtttgaatag tttttgacga cttgtgctcc
     2281 cgaatgaatc agaagcttct actaattctt taggaacttg tcgaatccct aaattcgtaa
     2341 aacgaacggt tggtggcaga gcaaagatga ctgaggcaaa tacccctgga accatcccga
     2401 taccgaaaaa tgcaactgct ggaatcaaat aaacgaatcc tggcattgtc tgcataaagt
     2461 caaggatcgg tttgataata ctttgggctt tactgctttt tgccatcaag atccctaatg
     2521 gtaccccaat gatgatcgag atcacactag ataaaagaac aagtgtgaca gtattcatca
     2581 aatcattcca tagaccttgg ttataaataa accatagacc gattaatgtg aacaacgtaa
     2641 gtcctggacg tttcttagaa ataaagaaag ctgctaccgt caataacaag ataaacaaag
     2701 gagctggaat cactaacagt aaatttgtaa tccccgacat cactgcctgt ccaatcgttt
     2761 gtaaaaatga aaataggcca gaaaaagttg tcgtaaacca ttctgtgata ttttctaccc
     2821 agtttgccac tggtaattga tagttcaata gattattcat gttcactcac ctcgcttgtt
     2881 tctgctaatg cttcaatcac actacctcgg atgacgacac cttttaattt tccatcctct
     2941 acaactgcaa gtggagtcgg tgagtcataa ataatattga aaatatcact taccaccatg
     3001 tctttcccaa tcaccgtcac attttcatct aggaagtcga tcaatggacg tttttgcttc
     3061 ctagcttcta acgcttgatc tgcagtgatg atccctttca ggtgtctctt tctgtcaaca
     3121 gccatcagca tgctgacttc ttcattacgc atccttgtca atgcaacgtt tggtccatca
     3181 gattcgatat tcgtcgtcaa tgcaggtacc atgatgtttt gagccgtaag cactttggaa
     3241 cgatcgactt cttccacaaa ttcacgtaca taatcatttg ctggattggt caatatttct
     3301 tcacctgttc cgatctgcat gatttcgccg tctttcatca aggcgattct gtccccaatc
     3361 cgtaaagctt cattcaaatc atgggtaatg aaaataatcg ttttttgaac attggcttgc
     3421 aggtccagta attcgtcttg catttctcgc cggatcagcg gatcaagagc cgagaacgct
     3481 tcgtccatca gcaagatctc aggatcattt gctaaagctc tggctaggcc aacccgttgt
     3541 tgcatcccac cagataactg actaggatat tggtctttaa atgaaagcaa actagaattt
     3601 tctaatgctt tttctgcttt ttcttgtcgt tcttctttag gtacaccacg gacttctaac
     3661 ccgtattctg tattttccaa gatcgttcga tgtggaaaca gaccgaagtt ttggaaaacc
     3721 atattgattt tatgacgacg gacttctcgc aattcttctt tgcttaactt cgatacatct
     3781 tctccatcaa tatagatact gcccgaagtt ggctcaatca gacgattcaa tagacggatc
     3841 aatgtggatt tcccactccc ggaaagcccc atgatcacga agatttctcc ttcttttacg
     3901 tcaaaattca cgtcatacac accaaccgtt gcaccggttt tctttaaaat ctccgttttc
     3961 ggctggtgat cattcatcat atctaaagcg gcttgtgtct ttttaccaaa tatctttgtt
     4021 aaatgtttta cttctacttt taccaaacaa attctccttt tttatgtaaa ttcatttttc
     4081 tttctgaaaa aagtgaccac actatgttaa catcatgtag tcactttgtc aaaaatgaaa
     4141 gaaatttgct tgtccaaact gaaaaaaact tggctaaatc tttgtaaata aaaggtttag
     4201 ccaagttaat atttttttaa tatttcacac aatcattctg caagctgatg ctccgggtaa
     4261 aaaaagtttg tcatacgctg tagtgtatat tcatttccaa taaaatgaac gatgtcccct
     4321 gccgtaaatt tagcataggg gccaggtgaa acaagcagtt cttcattatg agaaattgcg
     4381 ataactgtgg cgccagtcgc ctgccagata ttcaactcgc taattgaacg gtccagatgc
     4441 attgcttttt ctgataaaga taattcaaac ggaagtaaag gattcatctt atgtattcgc
     4501 ttcgtttgat tgaccagctg atccaataat tgagaaaaat gattcagctc atcttgttgc
     4561 ttctccacac ttgccatgat ttctgctttt gtatcttgga tggattgtac atcttgatat
     4621 tgcaatagga aatcttttgc tttttccttc gaagcaacaa atgccccact tccatgccgt
     4681 acttccatga ttccaagatc taccagcaca ttgatagcct tgcgggtagt ctcaggagaa
     4741 gcattgtacg tactggcaag tgttgagcgg gcatggatct tctcacccac tttatatcgg
     4801 ttttcaacga tacgttcggc taaatcaaca gcaatctgct ggtagcgcgg gcggacgatt
     4861 tttttctttc cagacatttt ctttcctctt tcttttttta ctttccctca tcttactatg
     4921 ctctagcaaa ataagcaaaa aaggggagaa tagcctcttg caacgactga tcatcgcttg
     4981 atctgttcct tttttactgg gcaagctgtt tgacagtcat cacaattctt accggatttt
     5041 aaacgagtat agacaattgc gcctgcactt ccaaagatta acacacttaa taagaatgtc
     5101 gccatcctat tcctctcctt ctaatgacaa tatagtataa aactggttct tggattttgg
     5161 ctgacggaac aaaacataaa cgagtcctat catcagtaaa atagcaagat acgtccctaa
     5221 cgctacctgt ccaccctcca ataagtgtcc caactgataa atcacaaaac taactaaata
     5281 agctaaaccg cattgatagc ctatggcgat ccaagtccat ttcttggcat tcatttcccg
     5341 atggatagcc ccaattgccg caaaacaagg cgcacaaagt aaattgaagg ctaacaatga
     5401 ataagctgct gcgggagtat atgtgtgttg tagcacttgc cagatttctc tgccattttc
     5461 ggatacttcc gcatgaccaa acaaaatacc aaatgtgcca ataatatttt ctttagcgac
     5521 caatcctgta atcgctgcga ctgttccttg ccagtttccc caaccaagcg gctgaaaaac
     5581 aactgccagg attcgcccga aaaaggctaa gatactttgg tcttcagaaa caggttgagc
     5641 ataaaaatta taagaagagc tgaaccagat cacgatacta gaaacaaaga taatcgttcc
     5701 tgctttttta acaaaagact tgctgcggtc ataggtttgt cttaggaccg ctgaccattg
     5761 aggaaaatga tatgcgggca attccatgat aaaaggagct gtatctccag caaacaaacg
     5821 tgtttttttc aagctgattc cagagaaaat aattgcagtc ataccaagaa aataggcaga
     5881 aggagctacc caagattgat gaggaaaaaa ggcccctgct actaaggcaa taatcggcaa
     5941 ctttgcagaa caaggcatga aggttgtgac catgatcgtc aaacgacgat cttgctcgtt
     6001 ttcaatcgtg cgactggcca tgacgcctgg cactccacat cctgtagcaa tcagcatagg
     6061 aatgaaggat tttcctgaaa gaccgaattt cctgaaaagt cgatccatga caaaagcgat
     6121 cctcgccata tatccgcagt cttccagaaa gctcaagcat aaaaacaata taatcaattg
     6181 cggtagaaat cctaacactg ctcccacgcc tgcgatgatg ccgttcaaga tcagctcctg
     6241 catccatccc gctacttgcc attcagctaa caatctgcca acatgttctg gtaaccatgt
     6301 accaaacaat gtgtcattga tccaatctgt ccccattgtt cctactgttt gaatagccag
     6361 ataatagatc agccacatca caaatgcgaa gatcggcaag gctaaccaac gattcgttgc
     6421 aatctgatcg attttgtcac tcatcgataa ttggaaagaa tcatttgaca caacacagag
     6481 tgtacatagt tgggtaataa attcataacg ttcattgacc agaatcgtct cactatcgtc
     6541 gtccaatagt ttctctgtta actggatcag ttgctcgatc tctttttgct gagaaactgc
     6601 tatctcgtaa tcctctctta ccttctgatc tcgttcaaaa tatttcattg cataccagcg
     6661 tttcttgccg ctttgttctc ctagtacatc ttcaatttca tgtaaagctg cttctaaacg
     6721 tggatcatat gtacagggaa caggaataga aggccgcttt tttgcagact cctgaatctt
     6781 ttcgattagt ttttcgattc cttgcttttt caatacgctg attggtaaaa ctggtacacc
     6841 aagaccatag gaaagctttt ctagattgat tttttttcct tcttttttga tgacatccat
     6901 catattcaga ccaatgatca taggaatgtc taaatccaat aactgcgtag ttaaataaag
     6961 atttcgttct aaattggtag catcaataat gttgatgatc agttcaggct gttcctgaac
     7021 caaataatct cttgcaatca cttcttctgg tgtataagga gacaaagaat agatgccggg
     7081 taggtcctga atatgaatgt tcggattttt tttcaacgat ccttcttttt tttctactgt
     7141 tacgcccggc caattcccta catattgatt cgaaccagtc aagagattga acaagctagt
     7201 tttcccgctg tttggatttc cgactaacgc gatattcatt ctttttcctc cctttgtatc
     7261 aagattagtt cggcctctga ctttcgtaac gtcagttcat accctcgcac tgtcagttcg
     7321 attggatctc ccagaggggc tagttttcgg ataactattt ttacatttcg cgtcaatccc
     7381 atatccatta accgtcgctt cactgcgcct tgtccgtgga ttgctacgac gatcccagtc
     7441 tctcctgctt ttaattgatc aagagaagtc cagctttcag aggaagcagt ctttttattg
     7501 acaaagattt gacctagtat ttcccgactt actgccactc gatgactttt taccagtaaa
     7561 atggcattgt tgcctgataa attgacgacg acgattttac ttccggcaac gatcccgata
     7621 ttttgcaaat ggcgttttgt tttttcttct gtttcgattc gttcgacttg ataaacgaaa
     7681 ttctgctttg cctgcgctaa ggtctgcata ttgattcctc tcttgtgaaa taaatcatgt
     7741 attaaaatca ttcattatat gttctaattt tcttacgtgt tacgcaaata aatgagaatc
     7801 attctcacat agaatactct cggtaattga gaatgtcaat tatacttgtg atattatgag
     7861 cgaatcttta gtattgatag ataaaaatga gaaaaaaata tttcttcata gttttccaca
     7921 attttttctc tattaaattt gctattttcc cacacgatac ttgttttcag ctcttttttc
     7981 aaaaacacaa aacttagtat tccacagttt ccacaacaca atatgtagtg tttgttgttt
     8041 gactttttta ctaagagttt tatactatct attatagata ataagaatgt gttagaggag
     8101 gcactcacca tgaacgtaaa aatcttttct aaaaataatt gtatgcaatg taagatggtc
     8161 aaacggtttt taacagaaaa tcaaattgct tttgaagaag tcaatatcga tgaacagcct
     8221 gaagcagtag actggttgaa agcacaagga ttccaaagtg ttcctgtcat tacttctgat
     8281 gcagaaacag ttatcggatt ccgtcctgat cagttgcgta aacttgccag ctaacatgac
     8341 taaaagaatc aaaacgtgat acatggattt gaagggcttg agacagcacc agtttttgtc
     8401 gcaaacttcc aaatcctttt ttaaagctta aaaacaatgc aatgatttgc aatcaagcat
     8461 catcaaatac gaaatgaagg ttgggcgtac gtatgagtct taaaaattta caagatgtca
     8521 gttatttcaa gctgaataat gaaatcaatc ggccagtcaa tggtcaaatc cctttgaata
     8581 aggataaaga agctttagtt gccttttttg aggaaaatgt caaaccaaat acgatgactt
     8641 ttccatctat tatggaaaaa atcaattact tgatcgatca agaatatata gaagcagaat
     8701 tcattcaatt gtattcacca tcatttattg aaaagctata tcaatttttg gacgagcaac
     8761 atttttcttt caaatctttt atggctgctt acaaatttta ttctcaatat gcgttgaaaa
     8821 ccaacgacgg ttccgcttat ctggaaactt atgaagatcg agtagccttc aatgcgcttt
     8881 actttgcgaa cggggatgaa gaattagcac ttgctcttgc agacgaaatg atccatcaac
     8941 gatatcagcc agctacacct tctttcttga atgctggacg taaacgtcgg ggcgaattgg
     9001 tgtcttgttt cttgactcaa gtcactgacg atatgaactc tatcgggcgc tcaatcaact
     9061 ctgctttgca attgtcccgt attggtggcg gcgtagggat tactttatca aatcttcgtg
     9121 aagccggcgc tcctatcaaa ggatatgagg gtgctgcaag tggtgtcgtt ccagtcatga
     9181 aattattcga agatagtttc agctattcta atcaattagg tcagcgtcaa ggagctggcg
     9241 tggtttattt gaacgttttc catccagaca ttattgcttt cctttcagca aaaaaagaaa
     9301 atgcagatga aaagattcgc gtaaaaactc tttctcttgg cgtgatcgta cctgataaat
     9361 tttatgaatt gacacgtaaa aacgaagata tgtatttatt tagtccatat agtgtcgaaa
     9421 aagaatatgg tgtcccattc tcttatgtaa atattacagc tgagtatgat catctagttg
     9481 caaatccaaa cattcgcaaa caaaaaatca aagcgcgtga tcttgaaaat gaaatctcaa
     9541 aattacaaca agaatctggc tatccttacg taatcaatat tgatacagcg aaccgcgaga
     9601 atccaatcga tggcaagatc atcatgagta atttatgttc agagatttta caagttcaaa
     9661 cgccttctgt gattaacggc aaacaggaat atgaagtatt aggaacagat atctcatgta
     9721 acttaggctc gacaaatatc gtgaatttga tgcaaagccc taactttggt caatctgtgc
     9781 gtacgatgac tcgtgcattg acatttatta cagatgcatc tgatatcgat gtcgtaccac
     9841 cgatccaaaa cggaaataag ctgaatcata cgattggatt aggtgccatg ggcttacaca
     9901 cttatcttgc aaaagaacaa atggaatatg gctcagagga ttcattagac tttacaaata
     9961 tttacttcat gctgttgaat tattggacac ttgttgaaag caacaatatc gctcgtgaaa
    10021 gaaaacaagt tttccataat tttgaaaaat cagcttatgc tgacggcact tatttcgaaa
    10081 aatacgtaac tggagaattc cagccaaaat cagaaaaagt caaagcattg tttgaaggca
    10141 tttttatccc aactgctgaa gattggaatg ctttgaaaca agcagtaatg aaagatggac
    10201 tgtatcatca aaatcgcttg gcagtagcac caaatggctc aatttcatat atcaacgata
    10261 cgagtgcaag tattcatcct atcactcgca tgatcgaaga acgccaagag aagaaaatcg
    10321 gtaaaattta ttacccagcg ccttatctat ccaatgagac gattccgtat tacacttctg
    10381 cttatgatat ggacatgcgt aaagtaatcg atgtttatgc aacggcacaa caacacgtcg
    10441 atcaaggcat gagtttgact ttattcatgc gttctgaaat cccagaaggc atttatgaat
    10501 ggaagacaac aacgaagcaa acgacacgtg atttgaatat tttaagacat tacgctttcc
    10561 acaaaggaat caaatccatt tattacgtac gtacctttac tgatgatgca gaagaaatcg
    10621 gaagcaatca atgtgaaagc tgcgtgatct aatatcatag atagattcgc ttattcatat
    10681 tttaattaaa ggagcattct catgtcagaa acatattatg aagcaataaa ctggaatgaa
    10741 attgaagata tcattgataa atccacttgg gagaagctga cagagcaatt ttggctagat
    10801 acacgtatcc cactttcaaa tgacctagat gattggcgta cattgtctca attggaaaaa
    10861 gatacagtag gacatgtatt tggcggtttg acactgctag atactgtcca atctgaaagt
    10921 ggcatggatc agttgcgtaa agatgtccgc actccccatg aagaagccgt tttgaacaat
    10981 attcaattca tggaatccgt tcatgccaaa agttattctt ctatttttag tacactgaat
    11041 acgaaaaaag aaatcgaaga aatttttgac tggacaaata cgaatcctta tctgcaaaaa
    11101 aaagctgagc gtatcaatga aatctacaaa cacggtacac cgctagaaaa gaaaattgcc
    11161 agcgtctttt tagaaacatt cttgttctat tcaggttttt atactcctct ttattattta
    11221 ggaaacaaca aattggctaa cgtagcagag atcatcaaac taatcatccg agatgaatct
    11281 gtacatggaa cctacatcgg ttacaaattc caattaggat tcaacgagtt acctgaagca
    11341 gaacaagaaa cgttaaaaga ctggatgtac aatcttcttt atgagcttta cgaaaacgaa
    11401 gaacgttata cagaagaatt atacgatcca atcggctgga cagaagaagt caagacattc
    11461 ctacgctata atgccaacaa agcattgatg aacctaggga tggatccact ctttccagat
    11521 actgccaatg atgtcaaccc aatcgtaatg aacgggattt caacaggcac aagcaaccat
    11581 gacttcttct cacaagtcgg aaacggctat ttgttaggtc atgtagaagc gatgaaagac
    11641 gacgattatt tgattggatt ggaataagga tttattttaa ttcaaaaatt tttcgaaaaa
    11701 taaaaagagt ttagcgtaca gatattttaa atgtacactg aactcttttt tatgcttatt
    11761 cacttgtttc ttccagcact tttggactgt ctaacttttc cgaaacatgt tccattcttc
    11821 tcaataaata gattttccgg atatttaata ttatcgtctt aatcactgca tagacaggta
    11881 tgcaaatcag catgcctaat attcctgcga cacttcctgc tccaatcaat accaagatga
    11941 tcgtcaaagg atggatattc attgatttcc caaataacaa cggcttgatc aaatttccat
    12001 ctaattgttg gatcactaaa atcgacaacg ccatatacaa agcttgaaat ggagagataa
    12061 acaaaccgac aatgattgct ggtaccgctc caataaaagg gccgacatac gggataatat
    12121 tcgtgattcc gcaaatgacc gcaagcaaca agctataagg ctgatcgaat attctcattg
    12181 ccaaaaagct cattacacca ataatcaaag catctaagat cgtactgctg atataggcag
    12241 ataatgtttc gtttaattct tttaccgttt ggcgtaactc tttacgaatc gctttcggaa
    12301 agaagtgaga caacgcatca ataaatttgt gcccatcctt gaacataaat agcaaaataa
    12361 atggaacggt aaataacaaa ataaaaaatt gcatcataaa tgaaatgatt tttgagacac
    12421 ttgcagataa actgactaat atgatattga acaaattact aagagataaa tttgctgatg
    12481 ctaattgttc ttccaaattg aaatttttaa actcttcccg ctgcgccaat tcatttaacc
    12541 atttgcttgt ttcatctgca tacattggca agctctgggt caattgaatt gtctgttcca
    12601 ttaactgagg cactacattc atgacagtta aaacaactaa aatgattacg accaaaaacg
    12661 tcaataaaaa accgaacact ctcgggatcc gatgcttttc gagaaaaaca acgattggat
    12721 cgaacatata atagataaaa ccagcaacaa gcaatggtaa aaaaattgcc gaaagcattt
    12781 tcaatattgg actaaaaata ttcggcattt gtaaaataaa gtacacgccg atgatcgtga
    12841 gtactagctc cactgtccag aaaaataatt ttgattgttt aaaacgtgat tgcatacatc
    12901 tcctccaagg tcctttgata cttctattct atcatttaac aaagagttac gcgctgagat
    12961 tttcatttgc ttaaaaaaaa caaaaaaaat aaacatattt taatgagtag acgagtactt
    13021 aaacaaaaac acggtttgga gtagtgacaa aaattatact gcagtccctt tttccaaata
    13081 aacggtgttc aaaagcttgc atcttcgtaa taagcccagc caaacgaaaa atataaggaa
    13141 ctatttttat ttggctgggc ttattacttg atgtaggaca tctattttac aacctcagat
    13201 catttattgc gcaatactga ctaaatgcaa ctttgtgata tttttgtgta cggacaactc
    13261 ctcgatcaca tcggcataag tgagcccttt tggaagatca atcgtataga tatttttgta
    13321 cactcggtag tcatcaacga attttacgtc aaaattcaca tcttcgatta cgatattttt
    13381 ctcttcaaaa taatcggtaa gaaaatcttt ggtttctttt ctatggataa attggatttc
    13441 taacttttta gtcgtaggta catggatcac gcgtttcact actgtgagtg caatagcaat
    13501 cccgataaaa ctgatgatcg caatggaata gtaacccatg ccgatggcga tccctaatcc
    13561 agcaattgcc cataaagaag cggcagtcgt aagtcccgtc accgattgtt tcgtgacgat
    13621 gatcgttccc gcgcctaaga aaccgacacc actcaccact tgagcaatca gccttgcttc
    13681 atctgaacga atcgttccag caagctgtgg atactctaaa gcatctctta atgcaccact
    13741 agcgatctca acttggatca atgcaatgat acatgctccc atacaaacta aaatatgcgt
    13801 acgcatacct gctggacgat ttttatattg tcgttcaaaa ccgattgctc cgccaaatag
    13861 catagcgatc cctaaacgta aaataatctc tggaattgtc aataccatat cattcatcta
    13921 aacaccctcc agtccaatat atcatgtctg aaaggagcag acaaaaaaag tgcaattttt
    13981 acctcttacg aaaaaaggac tgtgacaaaa tttttgtcat agtccttttt atgaataaac
    14041 ggtgttcaat cagctgaccc tcggtattac tcaacaaacg gcaaaatatg gggagctatt
    14101 tttcctttgt cttctctaat actcaggtca aaacgctgat ttcacaacct ctttagccta
    14161 ctattgaaaa ttacaactta cttgctgctt cttcatcgat gatcacaaca acattgtcgt
    14221 gattttgcaa tacacttgct ggcaaatgat tcgttacagg tccttcaatc atccctttga
    14281 ttgcatcagc tttgctttcg ccaaatgcca tcaagacgat ttctttactt ttcataattg
    14341 aaccgattcc cattgaaaca gcttttgttg gtacatcttc tgctttatcg aagaatcgtt
    14401 tgtttgcatt gattgttgat tctgttaagt caactactga agtcgttccg tcaaatgaag
    14461 caccaggttc attgaaaccg atatgtccat tttgcccgat tcctaagatt tggatatcga
    14521 ttggatgtgc atcgatgatt tgatcatact ttttgcatgc tgcttccaga tcttctgctt
    14581 ttccatctgg tacaaacgtt tctttgaatg gttttttatc aaataattgg acatccatga
    14641 aatgacggta gctttgttca tctgaaccgc ctagtccaac gtactcatct aagtttacag
    14701 aagtcatttc actgaaatcc aaatcgcttg aagtcatttc tttatataaa gtaactggtg
    14761 tgcttcctgt tgccaatcct aatacttttg cacctttgtt cataccttct ttgatgattt
    14821 caaatgcttt ttttccgcct tcttcagcgt tttttacacg aatgatttcc atagtgattg
    14881 ctcctttata ttttggtata gcccaattat agcattcttt ttttcttttt acaataatta
    14941 gtatagacca aattgcattt ttttcatttt cttgacaata aataggaatc cgtgttaggt
    15001 ttcataagat ggttcaatca aacaatccat gttgcatgaa aaccaagcaa gtgattcact
    15061 gtggacgctt tatgtctgca gtttttttat gaaaaaggag ttattatgag tatactgaca
    15121 ttaaacaaca ttacccagca atttggcgac aaaatcctct atgaaggtgt cgatctgcaa
    15181 ttaaatgctg gcgaacatct tgggctgatt ggacaaaacg gagccggtaa aagtacattg
    15241 attaaaatca tcactggtga gatcttacca gatgacggac agatccattg gcaaaaaaat
    15301 attcacaaag gttacctcga tcaatatgtg gaagtcgatg aaacattaac aatcgaagaa
    15361 tttctaaaaa ctgcgtacgc aaaagaatac gaaaaggaag aaaaaattgc ttttctttac
    15421 caaacatata gcgagacctt cgatgattcc ttgctggaaa aagctgggaa actccaaacg
    15481 gaattagacc aaggagtgtt ttatcaaatc gacaccttag ttgctgagat gagcagcggg
    15541 ttggggatcg atgtcttagg tttagattca ctgttgaaaa atctaagtgg tggacaacgt
    15601 tcaaaggtga ttttagcaaa actactttta gaaaacccag atgttctgat cttagatgaa
    15661 ccaaccaatc acttagatga tcagcatatc caatggctga cgcagtttct tcaggatttt
    15721 gacggtgcgt atatcgtgat ttcccatgac caagaatttc ttgatcagat caccacccat
    15781 atcgcagaca tcgagtttgg aaagattact aagtatactg gccatctaaa acaagcattg
    15841 aaacaaaagg aacaaaatcg cgaaagctat ttgcgccaat atcatgctca acaaaaacaa
    15901 atcgaaaaga ccgaagctta tattcgaaaa tacaaagccg gttcccgatc aacgatggca
    15961 aaaagccgac aaaaacaatt agataaaatc gaacggctga cgcctccagc ttcagcaagt
    16021 aaagctgtct ttgattttcc attctcgcct attgtcacga cattagcagt ggaaacaact
    16081 gatttagtca tcggatatga tcgaccgcta cttgcaccca tcaatttgac catccgcttt
    16141 ggtgaaaata ttgccattcg aggcttcaac gggattggaa aatctacttt attaaaaaca
    16201 ctgatcggtg agattgaaaa aataagtggc gatttccact tcccagataa cacaaaaatc
    16261 aattactttt cacaagatct gtactgggaa aatccattag aaacaccact acaatattta
    16321 agcagtcaat ttccaaaagc gactatcaaa gaattacgtc gccaactagc taaagcaggg
    16381 ttagttaatc aattagcaag tgaacctctc actacattaa gtggtgggga acaaactaag
    16441 gtgaaacttg cacagttgac aatgaaccaa ggtaatttac tgattctcga tgaaccgacg
    16501 aaccatatcg atcaagaaac gaaagaaagc ttacaagacg ggatacagaa atttccagga
    16561 acagtaatca tcgtctctca tgaacaagaa ttttatcaag atcttgtgca acgagtcatt
    16621 gagattgaac caaaataaac gtttgattga atagttgaaa aaaaggagct gtgacaaaag
    16681 ttttgtcaca actccttctt ctgaataaat ggtggccaat tagctgacct tcggtattag
    16741 ctcaaaaaac ggcaaaatat gaggagctat ttttatttgg ctattcttat tacttgatgc
    16801 agaacagctt ttcacaacct cttttcgtct attttttatt ttcgagattt ctctttcctt
    16861 taaaaacaac tgtttgaaag aagaacgcac atccttgaaa aacaagcccg ctaaccgtta
    16921 cacctaacca gccatactgc tgccacattg tcgtccctag caatgaacca gccgcacctc
    16981 caataaagta cataaacata aataca
//
LOCUS       DBBGSP010000061        16960 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000061 DBBGSP010000000
VERSION     DBBGSP010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16960
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.061"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            59..415
                     /locus_tag="ACIZE9_002406"
     CDS             59..415
                     /locus_tag="ACIZE9_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGC6094230.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
     gene            405..671
                     /locus_tag="ACIZE9_002407"
     CDS             405..671
                     /locus_tag="ACIZE9_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6094231.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            830..1831
                     /locus_tag="ACIZE9_002408"
     CDS             830..1831
                     /locus_tag="ACIZE9_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HGC6094232.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(2201..2815)
                     /locus_tag="ACIZE9_002409"
                     /pseudo
     CDS             complement(2201..2815)
                     /locus_tag="ACIZE9_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            3055..3300
                     /locus_tag="ACIZE9_002410"
     CDS             3055..3300
                     /locus_tag="ACIZE9_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094233.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            3398..3619
                     /locus_tag="ACIZE9_002411"
     CDS             3398..3619
                     /locus_tag="ACIZE9_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094234.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            3941..4621
                     /locus_tag="ACIZE9_002412"
                     /pseudo
     CDS             3941..4621
                     /locus_tag="ACIZE9_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
     gene            4761..5300
                     /locus_tag="ACIZE9_002413"
     CDS             4761..5300
                     /locus_tag="ACIZE9_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094235.1"
                     /translation="MWSLVGIVLIIFTVTAATEANYSHKIQSYKGRLVMTKKDVTRYT
                     SSRTGGLYDYAPLDALKYKDHLKKHEVKVGDRWENASHKAYNSKIVYTVEDADEQNIT
                     LPVFNYWGTVVKVNGKKSTIENDNGLVSIKGTGKRTIVEVSSTYPTTMILSLLISSIT
                     FIFLFTRYLIRCCGEMKID"
     gene            6320..7489
                     /locus_tag="ACIZE9_002414"
     CDS             6320..7489
                     /locus_tag="ACIZE9_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HGC6094236.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            7789..8481
                     /locus_tag="ACIZE9_002415"
     CDS             7789..8481
                     /locus_tag="ACIZE9_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGC6094237.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKINNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
     gene            8909..9301
                     /locus_tag="ACIZE9_002416"
     CDS             8909..9301
                     /locus_tag="ACIZE9_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094238.1"
                     /translation="MLDDRLTCSNCGTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKR
                     KLSHGYFVSYELYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGN
                     ICPGFMDQIIENESIESIENYVPVDLPK"
     gene            complement(9474..9677)
                     /locus_tag="ACIZE9_002417"
                     /pseudo
     CDS             complement(9474..9677)
                     /locus_tag="ACIZE9_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            9643..9840
                     /locus_tag="ACIZE9_002418"
     CDS             9643..9840
                     /locus_tag="ACIZE9_002418"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094239.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            complement(9883..10458)
                     /locus_tag="ACIZE9_002419"
     CDS             complement(9883..10458)
                     /locus_tag="ACIZE9_002419"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGC6094240.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(10613..11139)
                     /locus_tag="ACIZE9_002420"
                     /pseudo
     CDS             complement(10613..11139)
                     /locus_tag="ACIZE9_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            11596..13107
                     /gene="gadC"
                     /locus_tag="ACIZE9_002421"
     CDS             11596..13107
                     /gene="gadC"
                     /locus_tag="ACIZE9_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HGC6094241.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            13120..14520
                     /locus_tag="ACIZE9_002422"
     CDS             13120..14520
                     /locus_tag="ACIZE9_002422"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004351 - glutamate decarboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006540 - glutamate decarboxylation to
                     succinate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HGC6094242.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(14685..16120)
                     /locus_tag="ACIZE9_002423"
                     /pseudo
     CDS             complement(14685..16120)
                     /locus_tag="ACIZE9_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            16513..>16960
                     /locus_tag="ACIZE9_002424"
     CDS             16513..>16960
                     /locus_tag="ACIZE9_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA];
                     GO_process: GO:0043170 - macromolecule metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043412 - macromolecule modification
                     [Evidence IEA];
                     GO_process: GO:0044238 - primary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IbrB-like domain-containing protein"
                     /protein_id="HGC6094243.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVS"
BASE COUNT         5930 a         2518 c         2963 g         5549 t
ORIGIN      
        1 aattcgaatt tttatgttat atactataat ataaaatcaa tatatgatat aattgggtat
       61 ggaaaaaata tcttttgaaa catttaaaag acctaatggt catgatgaat ttttagaatg
      121 gttggaaaca ttaccaaaaa aagatagtgc gaagctttta cgtacaatag aagaaacaga
      181 aaagaatggg atgctagtag ctcaacggtt gaaatgggtg aaaaaattag acactaattt
      241 gtacgaatta agaagtaagg taggatcaaa catccaaaga gctatctatt tccatgtggt
      301 caatggaagg tatgtcatta cccatggatt tactaaaaaa acggagaaaa caccaataag
      361 tgaacttaaa catgcaaaag aacttagaga ggagtggttc acaaatgatg attaaaaaat
      421 tgattgaaga aaagcaaaaa gacaaagatt ttgcagaagc atatgaccgt gaaggaagaa
      481 aactcgaaac tgcggttgct ctttatcatg cacgggagga agcaggccta actcaagcgg
      541 agcttgcaca aaaagcacat acaactcaat ctactattgc tcgaattgag agaggggata
      601 acgtatcttt cgataaactt gatgatatcg ctagggcatt aggcaaaaag ctggtagtag
      661 aatttgctta aaagcgagtt gaaaatatac ctgtaatagg ctcctaacta atcaattagt
      721 ttagtgggcc tttttgtact aaatagataa aagttgtcct atagtgtaaa agtcaataaa
      781 ttttatacaa aaattacttt aaagagacat aaagagaaag gtacaataaa tgaaaaccat
      841 aaatctaata aaagtattta tagcatcacc aggtgatata gcagcaaaga ggaatgaagt
      901 agaagaaacc atatatagat ggaatataga aaatacagat aatacaaaag taattttgat
      961 gccaattcga tgggaaacga atgcgattcc tacttatata aataatagct ctgggcaaag
     1021 tgttattaat aaacaaattg tagaaaatag tgatatatta ttagcgattt ttggccataa
     1081 gttgggttct ccagttgata attatagatc gggaactata gcagaaattg attactttta
     1141 taaaaatagc aaaggcgagg taggggtttt tttcttagat gaaccagttc cacaagtttt
     1201 ggctgaagag tatatagaag ttaagaagta cagggactct ttagaagata agggttttta
     1261 tggaacatat agcaaagaca atatcagaag gtttctcaca aaaaaagtga attatttaat
     1321 tgagaaagca caaaataatt tagaatcaaa acgctttgat ttagattcta tttcttacaa
     1381 gacaccttca gtaattaaca aaaaagttac cggaactgat aaagattttg atgacaactt
     1441 agatattttt gatccaatag aatttgacaa tgatgaaaga ttgctgctaa tatatgcgtt
     1501 tatggatgaa aattctatct tttcaactga taattcaact tatagaaaag tagttcaatg
     1561 ggaaagtgat aacaatttaa ggagttactt gagtgataga gtatttgatg tactagaaaa
     1621 attaagtaaa tcgggaattt taaaggaaga atacgattct tcttttgatg agtatccatc
     1681 acgctatatt ttgatttcag aggactataa gaaatttaaa aggtattttt taaaaaatga
     1741 aaaaaagata tctgttatta tggagaaata caaagctcca atacaggctg atccattttc
     1801 caatttggat gaatcagatt taccgtttta aattttaaat agataatttc attttttagt
     1861 agcagaggta taaacttttt taatgtttga attgaaaaga aatgctaata ggtcgacttt
     1921 atgtttctct tgtgcaatcg taaatgcggg ggaccataaa attgatctat tatcgagtgt
     1981 gtataaaata aaattcaaat cttattagtt tacataagat acattatact aagttgtcaa
     2041 tgttaaatgc ctttaaataa ggacgattta tgcatcaatt atatttatgt taactaaatt
     2101 ctttttaaca taaatgtaat caacttagct agatgaatct aaaatgattg tctgtattga
     2161 tgacaaagct aattaataat tacgtgattc aaaaaagaaa tcatacaatt agttggtcga
     2221 tttctttttt tattcggtaa attgtttgcc tagtcacatt gtagtctgtt gcaatctttg
     2281 agatagcaac cccattctca agatcctgaa cgatactcct atagacaagg cgacgttgag
     2341 gatctttggt gtctgcactg tataacttag gacgaccttt atagacgccg tttgctttag
     2401 cgattttaat tccttgtgcc tggcgtcgtt tcgattcagt acgttcttgt tcagcaatca
     2461 tggctgagat ttaaatgatt aagtctttga tgaatttatc taggagagga tttccaattg
     2521 cttcagccat gatcggtaaa ctggtgataa taagtcgcac attcttcttc tttagataat
     2581 tcactgaatc gataatctcg tcataattgc gtccaagtcg atcaatggct tctacaataa
     2641 aaatatcttg ctctctgaca aaatctaaag cttcctggaa aatcggccga tgactaatcg
     2701 tcgctccaga ttgtttttcg ataaaaattt tttcagcgcc aaactttttc atttcttcaa
     2761 tttgacgttg ttcattttga tcgatggatg aaactctaat ataagcaatt ttcaaattta
     2821 ttccctactt ttctataacg tttataatac accctaatca tacgttagaa ctctaaattt
     2881 ttcaatgtta tatttttgtc tatttagggt aaactctaaa tagacaaacg gtttttgaat
     2941 tctaaaagtt aaatagttta taatagaaga aaaagaatgg ggtgacgatt tcttagattg
     3001 aaaaggaaag ataaatatta tagattatta cttttgacag ctgaagcagg atggatggat
     3061 tttccagaag ttgtaaaaga agttcaagag ataggtgcaa ctatttctga tagccgctcc
     3121 tctcctatga actatcagga tgcccatgga attaaaataa ttgatcaaga gagaaatgtc
     3181 agaaaataca caacaataaa tgagtgtgta attaatgaaa atctttgtag ggcaccgata
     3241 acgaaacaca ttaagaatag aagcaaagca aaagacggaa gaacttttac taccttctaa
     3301 gtttttttca tatttgtttg ctatacttag atctaaggaa ttagactttc gctgcccatt
     3361 atttaagttt gaggtagcgt cttgcgaggg atcaataatg gaagaagaaa aaatatttga
     3421 aaaacgctgg gaattggctt cagttgaaca aagagcaagg taccataatc taatgtcctc
     3481 ttaccgtaat attgattgga cttacaaaga aaagaagtac ttgctttggt tatgtcagtt
     3541 agatgtaaat acctttgaaa catttgaagt gattctagat aagattaaaa acagcaatga
     3601 aaaaagagct gatctataat ggttcgctct ttttatttta ttaactcttt ggttactata
     3661 tgtaaaatac agcttcatat tacaataaat ttcaggatac aaatttattt aagcatatat
     3721 aaatataatt gaaataggac ataaatatat gagtatgaga aaggtgattc catgtttaat
     3781 aaatgggcaa accacccaat gaactcgaga ggtagagata atttgaagga gacggacaag
     3841 ttctgggaag aagtatatag taaaaacggt tctgttgcaa agttttccaa aaaatctatt
     3901 ttagtgtaaa attgagaaaa aagacagaga ggacagagta atgaatcatt ttaaaggcaa
     3961 acaattcaaa aaagacgtca ttattgtcgc tgttggttac tacctgcgtt acaatctaag
     4021 ctatcgtgaa gttcaggaat tgttatatga tcgtggaata aatgtttgtc atactacgat
     4081 ttatcgttgg gtataagagt acagcaaagt cctctattat ctttggaaga agaaaaatag
     4141 acaatccttc tattcatgga aaatggacga aacctatatc aaaattaagg gacgttggca
     4201 ttatctttat cgtgcaattg atgcggacgg cttaacctta gatatctggt tacgaaagaa
     4261 acgggatacg caagcagcct atgctttctt aaaacgactc cataaacagt ttggtgagcc
     4321 gaaagcaatt gtgaccgata aagcaccttc tcttggctcc gcctttagaa agttacagag
     4381 tgtgggttta tatactaaga cagagcaccg aactgtgaag tatcttaaca atttaataga
     4441 acaagaccat cgacctatta aacgacgaaa taaattttat caaagtctcc gtacagcctc
     4501 ttccacgatt aagggcatgg agaccattcg aggaatatat aaaaagaacc gaagaaatgg
     4561 aacgctcttc ggcttttcgg tgtctactga aatcaaggta ttaatgggaa taacagccta
     4621 agatatttgg agttcagaga gggcgcgttt gattttcaaa cttcgcaaca gaaccgagaa
     4681 ccttgggttt tcaagtgctt tttggttcat taatcttaac catagtgttt ttaaagtgga
     4741 aaacaagcaa caaaaaaagt atgtggagcc ttgtaggaat agttcttatt atttttactg
     4801 tgactgcagc aacagaagca aattattcgc ataaaattca gtcgtataaa ggtcgtttag
     4861 ttatgaccaa aaaagatgtt acacgttata catcctcaag aactggaggc ctatatgact
     4921 atgcaccatt agatgcattg aaatataaag atcatttaaa gaaacatgaa gtaaaagttg
     4981 gtgatcggtg ggagaatgca tctcataaag catataattc caaaatagtc tatacagtag
     5041 aagatgccga tgagcaaaat atcacattac ctgtattcaa ttattgggga acagttgtga
     5101 aagtaaatgg gaaaaagagc actatagaaa atgacaatgg tttagtgtct attaaaggta
     5161 cggggaaaag aactatagtt gaggtttcat ctacgtatcc aactacgatg attctatctt
     5221 tattaattag ttcaataact tttatattct tatttacacg ttatttaata agatgctgcg
     5281 gtgaaatgaa aatagattag atagatatta taaatatgtt gattctattt tcatagcaat
     5341 ggagaaaata cattagcaat atataaaaga aggtatcaag agtcacagtg aatttattcc
     5401 gaaaagtgaa aagagcaaat ataaaattta atgaaaatat agaactaaat aggaaaacgt
     5461 agacgtaatt ttctacgttt tccttttcat atatattaaa tattacggaa aattatataa
     5521 actaatttag tgttttgttt gtaattccta attttgctcc acttttagat aatttttagg
     5581 tctatttaac tcatcagaca ttctatgctc atttttctcc aaatttgttt caactctttc
     5641 gtacttaatt ttgcgtattt gaaaattctt cttttagagt acttttatta cgatactagt
     5701 atgatatata tctatagcaa acagttaaaa tcttcctaaa ataagcgaat agcattccta
     5761 aaacctataa aatttttaga tgaagcgaca agtggacaat taataaacta cttgaacatg
     5821 aaattatgga tcacctttca aatttagaaa atggaattct tatacttatt gcgcaacatt
     5881 tattgattgc aaaattatgt gacaaaaaaa actagtagaa gaaagaataa tggcttgata
     5941 ataaagtact acctattaaa ggtagtactt tatttaattt agtataaatt aacatactac
     6001 tatattttag gtttcatatt atataaatta ataatatact accatttgtt ggtagtataa
     6061 tttaaaggta ataagttatt cttttattac tatgtttggg ttttatagca aagaaagttt
     6121 aataagagtt tggacctagc aaacaatatt aatgaggtca ttaaatctta ttatctttag
     6181 tgatataacg aaatatctac acagacaaaa tgatagcgta aaatattttg tgtaaataga
     6241 tatttagggt agaaaaaaag aaagtccatt ctgtaaaatt aaagttacca caaccgaaat
     6301 tttataggag gactttctca tgcccaattt tactacagaa attatggaaa cactaatcaa
     6361 taaaggtgat ttagatgaat tatttcgatg tcatttagaa ttagctgtta attcattatt
     6421 gcaggctgaa ttaacagctt ttcttgatta tgaaaaatat gatcgtgctg ggttcaattc
     6481 aggtaattcc cgtaatggga attattcacg ttcattcaga acagagtatg gagaattaaa
     6541 tttggtaatt cctagagata gaaatggtaa gttttctcaa caaactttac ctgcttataa
     6601 aagaaccaat gactctttag aaaccactat tattcagcta tttcaaaaag gaattactat
     6661 gtctgaaatc tctgaattga ttgaaaaaat gtacgggcat cactatacgc cacaaaccat
     6721 ttcaaatatg actaaaatag tttctgaaga tattattgcc tttaaagaaa ggtccttaga
     6781 atccagatac tctgtcattt ttatggatgc tactcacatt cctttaaaaa gacaaactgt
     6841 ttcaaaagaa gcagtttata ttgtaattgg cattcgatta gatggaacca aagaggttct
     6901 tgggtttagt cttgctccaa ctgaatctgc ttatgtttgg aaagagattc ttcaagacct
     6961 aaaagaccgt ggtttaaaag aggttttatt agtcgtaact gatggtttaa gtggcattaa
     7021 cgatagtatt catagtgttt atccaaatgc tcaatttcaa caatgttgtg tccatatatc
     7081 tagaaatatc gctcataagg ttcgtgttag tgatcgacaa gaaatctgta gcgatttcaa
     7141 attagtttat caagcaagtt caaaagaaga agcaaataat caaataaggt ttatgataga
     7201 taaatggaaa aagcagtatc cacgagtggt taaattgctc atgaatcctg ctatattaac
     7261 cttttataat ttccctccgt caatcagaag aactatttat tcaactaatt tgattgaagg
     7321 ttttaacaaa caattaaaga aatataccaa aagaaaagag caatttccta atgaagaatc
     7381 tctggagaga tttctagtat ctcaattcaa caactataat caaaagtttc tatgccgagt
     7441 tcataaaggt tttaaagaaa tacatgatac attagaatca atgttttaac ttgatcaaca
     7501 gaatgggctt ttccatttac acataattat tgacacaacc tattctggaa acttacaaat
     7561 aaaagcttat tcttcagcca ccttcgggtg gttatttttt ataaaaaaat gtaaaaaaat
     7621 attgatacat aaataaatta gttgtagtaa atagttttag aattgaattt ctctatcctt
     7681 tttaaataat tttttagaca aaaaacagaa agtgtctaaa gaaagcttga cgaagaaaat
     7741 aatttttaat aacttattta aggaaatttt ttgaaggaga agataaaagt gagaaaaaag
     7801 attattatta atgctggagt aattatagga ttgatgttag taattttctc cggaaagcaa
     7861 tatgctgata atattttatt atggggaggg gaagataata ttgaaaagat caacaacaat
     7921 ttaactatat tagacacagc tctagaaaat aaagagcaaa aaattagtat tttaaattca
     7981 caattgtctt caaacaacca aactcttgaa caactaagaa ctaatattga agtttccaaa
     8041 caaaaagtgg catctttaga aaacgacaag aatcaattag tatcagagaa aactaattta
     8101 gaaaatcaat tgtcagcaaa agactctgaa ttgcaaggaa aacaaaatga aattaatgcg
     8161 aaaatagacg aaattaacca aaaagtagct gaaataaatc gattaaatag cgattggaat
     8221 aatcgtttac aaaatgaaaa gaacaaattt aatgaagaac aatctactat taatagttta
     8281 aaccagcaaa ttaatcaaat gttgagtgaa aaaaataaca ttcaaaatca actgcaagct
     8341 actcagcaaa agctagaaga agaaaagtca aaaaatagta gtttgaataa ttacattgaa
     8401 aagcttcaaa aagctaaaaa tgatgtagag gataccgcaa ataaagcaca acaaattgta
     8461 aatgaacata caatccaata gatatagttt taatttaaca aatggtatgt ttggagataa
     8521 tgagatagaa tataaatgtc ataatattat acaatctaaa caccgtttcc ttttctattt
     8581 ttgatgacat cagtatatag ctactcgaaa gagtagtctt tttattattc tcgcttatta
     8641 ttgatatgaa aatttcgatt tgacaaaagg taccgaataa ttttgtaata tgaattatta
     8701 tcaagaagta attatgatga taacatatgg aaactagtta gtaataataa caggtgatta
     8761 aacttttgaa cgacttgtaa ttctatattt tttcttttaa gtaaaaaata taggtgattt
     8821 tttttgactt catatttata ataaagacac gtaaatcaat tatttttcat tttactttaa
     8881 ctaataatgt ttatttggag ggattattat gttagatgat agattgacgt gttctaattg
     8941 tggtacatta ttttactatg aggaagttag aaatattgta aaacatagaa aaaaagaaat
     9001 gcctatacgt tgtccaaatt gcaatgaagt tattaagcga aagttgtctc atggttattt
     9061 tgtcagctac gaactatatg aagaaagtaa aataaatctg aaaaaaaaac caaaatacta
     9121 taaaaatttg aaaactggag ctattataac tgaaaaagaa tttaaaaatt tagtgactga
     9181 agaagaaagc aggttttata atttgtctgg taatatttgc cctggattta tggatcagat
     9241 tattgaaaat gagtcaattg aatcaattga aaactatgtt cctgttgact taccaaaata
     9301 gaaaaaataa tcctgttttt acagtgaatt attttaattt tgattttcaa taaaaatata
     9361 ttacaataat aatcgtaata gctaatgaaa caatttctca atctttttac cactccaaac
     9421 agggagcgtc aataattttg tgtaaataac tcgtccttct gcaaaataat gggttactca
     9481 gtaaacattg aagctaatgt atccgtcact tgttggaagc ctttatggct tctatttaag
     9541 aatttttgat tgtatgtatc aaagatggat actaggaaac gctctagtga ttcttcattt
     9601 tgaaactgct cttttctgcg gctgtatttc ttgatttgtt tattgaaaga ttcgattgta
     9661 gaaccagaag gaatggagaa cacttttgaa ctttacaaca aaactactgt tgataaatta
     9721 attccaattt tagttccaac tgatttaaat ggtcatgatg ttttacttcg ttttaacgga
     9781 tttttaggtg aggattatag atacctaaaa atttctgatc ctcaaccttt aacagaataa
     9841 taaaaaacgt gtaatcaatt atttgattac acgtttttta tttcaatctt cgttgtagta
     9901 gtggttgcga cataccgaaa ggtaatcttc attacctcct actacaatct gttcacctga
     9961 ataaactgga ataccatcaa caatacgagc attcattaca gcctttttat tgcaaaaatg
    10021 gcaaatagtt ttaatttcct caattttatc agcaaatgtc aataatgctt cggatccctt
    10081 gaagagatta ttttgaaaat cattcttcaa tccatagcaa attactggta cttcctcatt
    10141 cattacgata agtgatagat caataatatt ctctctactt aaaaattgag actcatcgac
    10201 caaaatacaa tcaacttttc cgtactgatc aataatctcc actaattctc cgtacacatc
    10261 catttcagaa gtaattgcaa tagctggttt cgaaacacct atacgactct caacttttcc
    10321 aaatcctgat cgagtatcta ttgcgcttgt cattatgata actctcttcc cttgttcttc
    10381 ataattatga gccactttca gtagctcaat actctttcca ctattcattg ttccatatct
    10441 gtaaaataat tgtgccatta aatttattcc cttcttttac aattcaatta ttccttaatt
    10501 ccatctgctt ttatgcagct gctcgtttat tccttgatat gtctataaca tctactatcc
    10561 ctaaaaccaa tttataagcc attagagatg gtattcctga acatctctca tattgttttt
    10621 tgagtggtat atcatctgaa aaactgaagg aatcatgaaa atagcgacat acttatcatt
    10681 tagagttcta actttaaatg catttacttc ttcagtcagc actttagtca tgttggacat
    10741 ggtttggggc gtgtagtgat gcccatacat tttctcaatc aagtctgcga tttccgacat
    10801 ggtaatacct tttcggaaga ggtgaatgac ggtctcctct aatgtgtcat tcgtccgtct
    10861 ataagcagga acagtctgtt gcttgaactc gccattgcgg tcgcgcggaa tctggagatg
    10921 aagttcccca tactcggtct tgaccgtacg gtcataggag ccgttacgag aattacccgt
    10981 gttaaaacca atgcgatcgt acttttcgta atcgaggaaa gccgttaact ccgttttgag
    11041 aagcgtattg acagcttttt ccaaatggac acggaataat ccattcaaat cgcctttgtt
    11101 cgctagagtc tttaggattt ctgtagtaaa atcgttcata tggaagtcct cttttctgtg
    11161 aatgtgttgt ggtaactcta ttctacagaa gggacttcct tttttctatt tacacaaaat
    11221 attttacact ctcaacaaaa gtatcttcga ttaatacttg ctcaagttat gtgcagctac
    11281 gaaaaagtag gtaccgaggt actttctttt tcgcagcttt ttttggactt atgagaagta
    11341 cattcgctgg aagaatacga tataaaacga gctttttcac taaagatatt aatagagtga
    11401 aagaaacaag cttttgttgt cagttttttc acttttctaa aaatgaaaat aaaaaattct
    11461 ggaagtggag aagaattttg cttgctatac tttgtcttgt agaaaagagg tagacaaaat
    11521 aatgcaagct caaataagcg attttccata accttggtag gaatgacaaa ttaaatagga
    11581 aagggaagta ataatatgaa taaaaaaaag ttatctctat tcggtttttt tgccctgaca
    11641 gcttccatgg ttttgactgt ttatgagtat ccgacctttg caacatcaca attacatttg
    11701 gttttctttc ttcttttggg aggtatttta tggtttctac cagttgcttt atgtgctgca
    11761 gaaatggcaa cagttgaagg atggaaagat ggtgggattt tcagttgggt tagtcaaact
    11821 ttaggagaac gttttggttt tgcagctatt tttttccaat ggtttcaaat tacagtaggt
    11881 tttattacaa tgatctactt catactagga gcgctgtcgt atgtaattaa ttttccagag
    11941 cttaatacag atccatttat caagtttatt ggtgtattag tcattttctg ggtactgact
    12001 ttttcacagt tgggcgggac caatcgtacc gctaaaattg ctaaagcagg atttgtcatt
    12061 ggaattgtta ttccttcgat cattctcttt ggtttagcag cagcctactt tatcggcggt
    12121 aatccgattc aaatggctat taatgcgaaa gcttttattc ctgacttttc tcagctttca
    12181 actttagtag tatttgtatc ttttatattg gcttatatgg gcgtagaagc ttcagcatca
    12241 catattaatg agctggaaaa tccccaaaga aactacccat tggcaatgtt tttactagtg
    12301 attttggcca tcgccttaga tgcaatcggc ggtttctcag tagcagcggt tattccacaa
    12361 catgacttgt ctctcagtgc tggtgtaatc caaacatttg aaacgcttat tttacatttt
    12421 aacagtcatt tacattggtt ggtaaaagtg attgctctca tgattgcctg tggcgttatg
    12481 ggtgaagtta gttcttgggt agttggtcca tcacgaggga tgtttgcagc tgctcagcga
    12541 ggtctgttac cagttttctt ccggaaaact aataaacaag acgttccagt tccgttgatt
    12601 atgatacaag gaattatcgt tactatttgg gcagcagtct taacttttgg tggaggaggc
    12661 aacaatttat cattcttagt agcaatctcc ttaactgttg tcatttatct cgtaggatat
    12721 ttactatttt tcctaggtta ctttgtatta gtttttaaga aaaaagactt aaaacgaact
    12781 tacaatgtac caggaaaaac tgttggcaaa acgattatcg gtggaattgg ttttatttta
    12841 tcagtgttcg cattgcttat ctcttttgta ccaccagctt caattgcagc tagtgagcac
    12901 cgaacatacc aaatcatact acttattagc tttgtagtga ctgttctttt accttttatc
    12961 atttatgaag tacatgataa aagtgctcac acaactattg aggaacctac tcacgtgaaa
    13021 gctgaagacg ttaatcccgc tgtttatcca gctgctagag gagagcacca cgttacaaaa
    13081 aatgatgaac atattttaaa acattaggag gaattcatta tgttatacgg aaaagataat
    13141 caagaagaaa aaaactattt ggaaccaatt tttggctctg caagtgagga tgttgacttg
    13201 cctaaatata agttaaacaa agaatccatt gaaccacgaa ttgcttatca attagtacaa
    13261 gacgagatgt tggatgaagg aaatgcgcga ttaaacttag ctactttttg tcaaacgtat
    13321 atggaacctg aagcagtgaa attgatgacc caaacgttag aaaaaaatgc aattgataaa
    13381 tcagaatacc cacgaacaac ggaaattgaa aaccgctgtg taaatatgat tgctgattta
    13441 tggcatgctc caaataatga aaaattcatg ggaacttcaa cgatcggctc ttcagaagcc
    13501 tgcatgctgg gtggtatggc catgaaattt gcttggcgta aacgtgctga aaaattaggt
    13561 cttgatattc aagcaaaaaa acctaacctg gtgatctctt ctggttacca agtttgttgg
    13621 gaaaaattct gtgtatattg ggatgtggaa ctgagagaag tcccaatgga tgaaaaacat
    13681 atgtcaatta atctagatac tgtcatggat tatgtggatg agtacacaat tggtattgta
    13741 ggtattatgg gtattactta cactggtcgt tatgatgata tcaagggtct gaatgattta
    13801 gttgaagctc acaataaaca aactgactat aaagtataca ttcatgttga cgctgcatcg
    13861 ggtggctttt atgcaccatt tactgaacct gatctagttt gggattttca attgaaaaat
    13921 gttatctcaa ttaattcttc aggtcacaaa tatggtttgg tatatccagg tgtgggttgg
    13981 gtcttatggc gtgaccaaca atacttacca gaagaattag tatttaaagt tagttactta
    14041 ggtggagaaa tgccaactat ggctatcaac ttctctcata gtgcagcaca actaattggg
    14101 caatactaca actttgtacg ctatggcttt gatggttatc gtgatattca ccaaagaact
    14161 catgatgttg ctgtttattt agccaaagag atcgaaaaaa ctggtatttt tgaaatcatt
    14221 aatgatggat cagaattgcc agttgtgtgc tataagctga aagaagatcc caatcgcgaa
    14281 tggacactat atgatttatc tgatcgtctg ttaatgaagg gatggcaagt cccagcctac
    14341 ccattaccta aagacttgga tcaattaatt attcaacgct tagttgttcg agcagacttt
    14401 ggaatgaaca tggctggtga ttatgtacaa gatatgaacc aagcaattga agagttgaat
    14461 aaagctcata ttgtttatca taaaaaacag gatgtgaaaa cgtacggctt tactcactaa
    14521 aattcttcag agaaatataa aagaagttaa ttaactaata aaaggagttg tgattaccac
    14581 acagctcctt aaatctattt gaataaatat atgatattca tttgttacac tctcaatctt
    14641 agctgttgtt ctattcatca ttactcttat tgtaagtagt tcagtcaaat ttgcttgttc
    14701 aattgatcga taacagtatg aattgtttga aaagtaatcg gatatataat tgttttctca
    14761 ctacctaagc cttcttggta taaagaacta tcgcaaagta taatccgctg agtacaaaag
    14821 aaagtgtcgt ctactatttc tctaagttgt ttacaaatga tattactaat agaaaagtgt
    14881 tctcccaaaa tgtcttctaa ctgttgtcga tagtataaat acctaaagtc tgacggagct
    14941 actatgaaca cttcaattgg agatttccgt ttatgctcat ttaaaagact taaactaatg
    15001 gttagtttac gaatagaatt ctcattccaa cgcagaaata aattgttttg ttttcgccat
    15061 tgttcaagaa tttcatgaac ttctaagtac aaagcgcgtt gctcttcatt taacaagtaa
    15121 gtcttatcag gttgaaatat ctgaatatca gcccaaagtg agcggataaa cgggagaagt
    15181 gctttatcaa aaagtatctg attttcttca gatatattca gagataagat aagtttttga
    15241 ctgagctcaa tcaccaaagg gttatctgct acatggtttt gataaacaac gttcaagtct
    15301 ttttgtaaca attcaaagtt atcgcataga taatttctag agttgaatag aaagtagata
    15361 taaaggcatt catcttcgtc atgacataaa gagaaagaaa gttgctctaa tcctttctgt
    15421 attagctgaa acaagggagt atgtcgggca actctttttt cttcctgact aaaatatatt
    15481 gggttagtct tagatctctg caaaccgata gcgataccta ataaaataaa ttgtttttca
    15541 actgtagggt aacttcttga aaaaaatgtt tttctacata atcaatcaat tgttgaccgc
    15601 tttgaataat tgatttattt agctggatca actctgtccg atttgtctca tagattatcg
    15661 ttagtaacaa acttcgataa tccttttcag gaatttcaaa atggccatca gcatttaagt
    15721 actgcatttg tttaaaaaaa ttaatcaact catttcgtaa gttgtaaact ttgcttaacg
    15781 aaatgaaggt agtatcagct atattactcc aattgtgttc ccctgataaa taatgtccta
    15841 gtacattgaa aaagtcagag cgctgataga tgagttgagt gagtgccaac ctcgaaaacg
    15901 aagagtcgaa tgcgactgta aagctacttc tagatttctc cactgaaata atttgctgat
    15961 ggagtatgtc ggtaatgcat tccaagtcgt tagtgacagt gagtgggcaa acgttcaatt
    16021 gatctgctat ttcgcgaatc tgaatggtcc ctttttcgtg taattgctca caaatgtaaa
    16081 cttgacgaaa aatacttttc tccagatagg tttccaacat agtactcctc ctagtcattt
    16141 tatacataac tattataact ctaccaatcg gaatagtcct gtaatatatt gaatcaaaaa
    16201 tataaattat aaaataatta gatggggtat ttggtttaag tatcccttat atagtaataa
    16261 atttataggt gtgattctcg aattaatacc cgaaaatgtg agagaatttt tatggatttt
    16321 ttaggataca aattaattat ttttgctttt atcctgatta ccagtccagt actgtcggta
    16381 tcccattttg cagcaaaatc atgttgataa agtgacaaga agactgatga gatatattat
    16441 ccaaattgag aagataatta atcggattct tgagtatacc ctacttttta agaaagtagg
    16501 gtatacaagc gtatgaataa agacataact ttccctgtga tggacgttcg gcttgttcca
    16561 attaccaaaa tacaggcgaa cgattataat cccaatcgag tagcgtctcc ggaaatgaac
    16621 ttattggagc tttctatcat tgaagatggc tttactcaac cattagtttg ttattacaag
    16681 gaaaaagaag agaagtatat cttggttgat gtgcttcata ggtatcgtgt tgctaaggaa
    16741 agactcaact taaaagttgt accggtaaca gttattgata aacccataga agaacgtatg
    16801 gcttcaacaa ttcgacacaa tcgtgcaaga gggacccatg aaataagagg aatggaaatt
    16861 gtcatccaaa gattagtaaa aaatggatgg tcagacaaga gaatatccaa agaattaggc
    16921 atggacattg aagaaatttt tcgctttaag caagtgtctg
//
LOCUS       DBBGSP010000062        16344 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000062 DBBGSP010000000
VERSION     DBBGSP010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16344
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.062"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(129..785)
                     /locus_tag="ACIZE9_002425"
     CDS             complement(129..785)
                     /locus_tag="ACIZE9_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGC6094244.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            978..1256
                     /locus_tag="ACIZE9_002426"
     CDS             978..1256
                     /locus_tag="ACIZE9_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094245.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            1275..2483
                     /locus_tag="ACIZE9_002427"
     CDS             1275..2483
                     /locus_tag="ACIZE9_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6094246.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(2631..2996)
                     /locus_tag="ACIZE9_002428"
     CDS             complement(2631..2996)
                     /locus_tag="ACIZE9_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HGC6094247.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(3143..3916)
                     /locus_tag="ACIZE9_002429"
     CDS             complement(3143..3916)
                     /locus_tag="ACIZE9_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGC6094248.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            complement(4090..4950)
                     /locus_tag="ACIZE9_002430"
     CDS             complement(4090..4950)
                     /locus_tag="ACIZE9_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HGC6094249.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            complement(4950..6368)
                     /locus_tag="ACIZE9_002431"
     CDS             complement(4950..6368)
                     /locus_tag="ACIZE9_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HGC6094250.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            complement(6425..6874)
                     /locus_tag="ACIZE9_002432"
     CDS             complement(6425..6874)
                     /locus_tag="ACIZE9_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6094251.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            complement(7319..7582)
                     /locus_tag="ACIZE9_002433"
     CDS             complement(7319..7582)
                     /locus_tag="ACIZE9_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGC6094252.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            complement(7681..8976)
                     /gene="rho"
                     /locus_tag="ACIZE9_002434"
     CDS             complement(7681..8976)
                     /gene="rho"
                     /locus_tag="ACIZE9_002434"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HGC6094253.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            complement(8973..10244)
                     /locus_tag="ACIZE9_002435"
     CDS             complement(8973..10244)
                     /locus_tag="ACIZE9_002435"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGC6094254.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            complement(10409..11278)
                     /locus_tag="ACIZE9_002436"
     CDS             complement(10409..11278)
                     /locus_tag="ACIZE9_002436"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGC6094255.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            11381..11593
                     /locus_tag="ACIZE9_002437"
     CDS             11381..11593
                     /locus_tag="ACIZE9_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094256.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            complement(11570..13180)
                     /locus_tag="ACIZE9_002438"
     CDS             complement(11570..13180)
                     /locus_tag="ACIZE9_002438"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGC6094257.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(13402..13647)
                     /locus_tag="ACIZE9_002439"
     CDS             complement(13402..13647)
                     /locus_tag="ACIZE9_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094258.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            complement(14373..15713)
                     /gene="glnA"
                     /locus_tag="ACIZE9_002440"
     CDS             complement(14373..15713)
                     /gene="glnA"
                     /locus_tag="ACIZE9_002440"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGC6094259.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(15741..16133)
                     /locus_tag="ACIZE9_002441"
     CDS             complement(15741..16133)
                     /locus_tag="ACIZE9_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC6094260.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         4663 a         3463 c         2781 g         5437 t
ORIGIN      
        1 tggtaaacgg tgttcaatca gctgaccctc ggtattagct caaaaaacgg caaaatatga
       61 ggaactattt ttccgtttgt ttctctaata ctcaggtcaa aacgctgatt tcacaacctc
      121 tttgttcatc aaaagataat attgtcttct aacaagtcca tattcaaaat aacgatatga
      181 tggtctttaa cggtgataat accatctttt ttcagttgtt ttaaaattct gtttacactg
      241 ctagcagttg agatgccaca aaatttggcg atttcttcat tcgtgatcga aaaatcgatc
      301 agcatccctt cttctgtccg cacaccgaat aaatcatata attcgtaaag ttgcgtacaa
      361 acagctccca gctttccgtt taatagcatt tgctgcattt ttttcatcga ataaagcaga
      421 cgatagcggt aatactcttt tacatagtgt tgtagctttg ggtcttggtt gatattttgc
      481 caaaagcgca cacgattgat tcgataaaac tctgcatatt ctgattcaac tcgaatatta
      541 tacggcgaat cgatgaattg tgaatattcg tcttttaaaa gagagacgat ttcaagatct
      601 ttgatatagc gaaggttaaa ttctctccca tcatttgaaa taacacttgc ttttaccgtt
      661 ccctctttca agatatacgt atgggaatct tccatccctt cgaatgtcaa atatttatga
      721 tatcctttgc gtataatcgg aaaatcattt ttatccaaat attcctttaa gactctacta
      781 tccaatgatg ctcccccatc caaactttca tctaaaaaga tcatacagta ctttaaaact
      841 ttttaaagtc caaaggtatt ttactaatga tattaacatt tgttaagtac ctttttccat
      901 cacttatgcg atttttttcc ttttttttat tcgttatact gcagaagtaa aattttttaa
      961 gaatagaggg aaaaaacatg aattactgga tgaacacaat cattaatcga ttagaaacag
     1021 catatcaaac aagatttgat atgaaagctt ctttagtctt tttaaatgat gcgtatcaaa
     1081 actcgatcga attgatcaaa gcagtggatg agaatccaac aaacgaatgc gaagaatttt
     1141 taaatctgtt tatgtctaca agagatttat ttattcgcca acttgttgat cgctatccat
     1201 ccaattatca cgatgtagaa gttcaaatac aaaaattaaa agcatattca gcttaagggg
     1261 aatgtataac atacatggaa aagaaattat ttaataaata ttttattgga atcacattga
     1321 tcaattttat tgtctacctg atttattatc tgttgatggt catcatggca gtcattgcgc
     1381 aagacacctt acacgccagc ttgagccaag caggttttgc ttctgggatc tatatcatcg
     1441 gaacattgct ggcacgctta ttcatgggga aacagttaga actatttggt cggaagttta
     1501 ccttaagagg cggcgcgatc ttctatctcc tttcaacatt agcatatctt tatacgccaa
     1561 ctatcggggc attgtattta gttcgattct tgaatggatt cggctacggt acagtttcta
     1621 cagctacaaa tgctatcgtt actgcatata tccctgcatc taaaaaaggg gaaggcatca
     1681 attattatgg attaagtact agtttagctg ccgctgttgg gccattttta ggaatgattt
     1741 tgctgaatat gactgatttt cgtttcatta tctggttttc aattgtactg gtcttctttg
     1801 ttacgattgc ctgccttgtc tttcctgtaa aaaatattcc attatctgaa gaacaaaaaa
     1861 tatctcttcg ctcatggaat atcaatagtt ttattgaaaa gaaagcactt ttcattacag
     1921 gaattgcctt tttgatgggt ctttcttatt caagtgtttt atcattttta tcttcttata
     1981 caaaagtaat ccacttagtt gctgctgggt catttttctt cgtcgtatat gctttggtca
     2041 tcacatttac acgtccattg actggaagga ttttcgatgt caaaggagaa caatacgtga
     2101 tgtatcctag ctatttattc ttaacagcag gattattttt actgagtgta acgacgaata
     2161 gtgtgacatt gcttatctct ggagcattag tcggcctagg ttatggtacg tttatgtcaa
     2221 atggacaggc tgtttgttta aaaatcgtcc gcgaacatcg aatcagtatt gctttatcta
     2281 cctactttat tggtttagac ctaggcttag gcgttggtcc ttatttgatg gggatgctaa
     2341 aatctcttac ttcatttaga ggattgtatg tgattgccgg agtcattcca ttgatatgta
     2401 cagcactcta tcttgttaat ggccgaaaac atagtcatga agcagagggc gaattgattg
     2461 aatcattgaa aaatgaaatt tgatcttgat gaatagataa aaaaaaccgt tcagatctga
     2521 aaataatctg agcggttttt tgagtaaaaa tagtttatga ttattcttaa ttaaacatct
     2581 atttattttt aaagctttca tttatcgata agaatagttt aactgttgat ttattccatt
     2641 ttccgttcat ctggtacgat gccttgactt agcaaccact tgtggaagaa ccattctgcc
     2701 acaccgatca atagagcagg aatcaatact ttcatccaaa tatcgactgt atcattcata
     2761 aaatatagat agagccacaa gataactgca gctgaaccag catctgcgat cgtcgctgcg
     2821 atgttcccta ctttacgtaa gatcaacaga tcccctagca catagatcat gactacaata
     2881 attaccccaa caatcgttga atccataaag ctaacaccgt ataaacctgt cagcacgacc
     2941 cacagaatcg cccagatcat gattgccttc actaccaacg ccttcacatg tttcattttc
     3001 tgcactcctt tctcctggat aaaaaagtaa gattatctaa caagataacc ttttcattat
     3061 tataccatcg gctgagagaa gcgagcaaag ataaggtcct atctaaaaat gaggaagcca
     3121 cttagaacat tcacgtaata atttatccgt acagacattc gatatggtgt tcctttactt
     3181 tcgcatactg ttcttttgtc agttctttac ttgtcaccag ataatcgatt tcatgaaaag
     3241 caatggcttg atgcatgaat ttatgtgcaa ttttttgctg tgtaactaaa acggcaagcc
     3301 ggtctgattg ttttctaaaa gcttttttga ccattgcctc tccttcatga gtttctgtta
     3361 ctccttggct gaaatctagc ccgcgacaac tcattatcgc taaatccgca taatatgaca
     3421 atgcatcgtt ataggctttt gaaccgttga ttgttgctcg tttcggaaca attgcccctc
     3481 ccaatacaga tacttttgcc gttgtatatt cactcaacat agcagctgtg acgatgccat
     3541 tcgtaatgat ctgcaaacca tcaaatcttg ctaggtttct gactaagtgt aaagaggttg
     3601 tactggaatc caagaataag accatatcat ctcgaatcaa agaagaagct gtatctgcaa
     3661 tcttacgttt ttctgtttct tcttctaatt tggtgatctt catcaggtaa ggcacgtcaa
     3721 tttttcgatt gtcaataagc atggcgccac cgcgaactct acggatcaat ccactttttt
     3781 ccagaaaaac aaggtcacgt ttaatcgtgg cttcgctata atttactaac tcgatcaaat
     3841 cggtgactct tgcaaattgg ttgtttttta gataattcac aatctcctgc tgtctattct
     3901 ccacttcatt caacataaaa tcaccccatt tactttatat agtaacagga aaaaagaggt
     3961 tgtgacagaa gtgattggct tcgagaaata agaagaaatt tttcgaaaaa actacttctg
     4021 aacatcgtgt gtggttaaga gggtatgaca agactattgt cataccctct tgaccacaca
     4081 tttttatttt tagtataaac tagccttgcc tactgtgttc aaaatttcca ttttatgttt
     4141 gaccacttct tgtacctttt tattagctgc tggataaatt gcattcggct cgtacatcga
     4201 tggattttca ctcaatattt ctctcaaagc attgaaaaag acgcttttaa gatctgagct
     4261 caaattcact ttggcaactc cgtattttac tgcttcgctg acttctgcgt ccggattacc
     4321 tgaaccgcca tgtaaaacaa atggaagatc gatttgttgg ttcaattctt tcagtaagtc
     4381 gatatttaat tttggagttc tgtttttcgg atacaagcca tgcgctgttc caattgctac
     4441 agcaagtgta tcgattcctg tttctttcac aaaaatcttc gcttgatcag gatctgtata
     4501 aatgattgtt tcagcacctc cttcagcaga accattattc ccaatcgttc caagctcagc
     4561 ctccactgag acatttaccg catgagctaa cgcaaccact tttttcgtaa tctgtacatt
     4621 gtcgtcgaat gatttcaaag acgcatcgat catcacggaa gaatagccgt ttcgaatcgc
     4681 ccgtaagaca tcttctatcg taccgccatg atccaagtgg ataacgatcg gcagtttact
     4741 tgtataagca taggctctta ctgccgcaac aaactcatca cttaaatagg cgatttcatc
     4801 aggatgaatt tctaagatta ctggtgcttc taatctctct gcttcttcga tgattgcttt
     4861 catcatatca tagctgcaaa tattgaaggc tggtactgca aattgattct ctttagccac
     4921 tttcaataac tctttcattg tatataacat tacgcttcca cctcatttgt tagattttca
     4981 tttttcgtcc acttgtcttg ttttttctct ttcactgttt ttttcaatag tccaagcata
     5041 aaggctgtag tgactgtacc tgatgcaatt gccaagacat acataggtaa attgttcata
     5101 acatttggaa ttagcatcac ccaaatccct ccatgaggtg ccattgaagt aactcctact
     5161 gccatggaaa tccctgcagc gactgctgaa cctgtcatca aactaggtat cacgcggatc
     5221 gggtcagata ccgcaaacgg tatagcacct tctgtaatat acgaagcgcc taaaatccag
     5281 catgattgac ctgaagtccg ttcttctttg gtaaatttat gtttgaataa taaagtggct
     5341 aaagcaatac ctaggggagg tgtcattcct gcagccatac aagcagcaat cggtgcattt
     5401 actccagctg acatcaaacc gatcgagaaa gtcgaagtcg atttattgat cggcccaccc
     5461 atatcagctg ccatcatgat cccgataagt aatccgaaca atagcccgga tgtatttccc
     5521 aagctattca gccaatttgt caaagcatcc aacacccatg tgatcggttg ttcaatcaca
     5581 aataccatca aaagcccaat aattaagatc gataaaaagg ggacgacaat cagctgataa
     5641 atagcagaaa attctttttt tacgctaatt ttatttgcca gaaaatcaca gatataccct
     5701 gctagcacgc caccaatcat tccgccaaga aaacctgaac cacctgtaga ggccagtaat
     5761 ccggcaacaa ttcctggggc aaaacctgct tttccagcaa tcgatgtagc aatccccgcg
     5821 cctaacgcag gaaccatcat ggcaaacgct gtatctcctc cgatccttga aaatgcagct
     5881 gctaacacat tatagtctgc tgagttggga tcagccgctg taatcccaaa ggcaaaactc
     5941 agtgcgatga tgattccgcc tgcgatcaca aatggaagca tgtaattcac accattcatg
     6001 aaatgattat agattgtcgg ctttttctca tttgcagctg gttctttttc attagacaca
     6061 acgaatacgc caatatctct caatgcttcg tctattacta cttgcggttc tttgattgct
     6121 cggcttgtag agacacgctt tacttttttc ccggcaaatc ggtccaattc gatttcttta
     6181 tctactgcaa gaatgattgc atctgcctct ttgatttctt gttcagataa ctgattttct
     6241 gtttttacac cttgtgtttc gaattttgct tgatggttta gatttcttgc tgttacttct
     6301 aatttttctg ccgacatata agtatgagca attccagtcg ggcaagcagt tacaccaacg
     6361 attttcatga ttattttcct cctttttctt cactatcgat actcggacaa agactctact
     6421 attttcattc ttgactaatc tgtctgatga tatctgctgg cgtagtggct tcttttattc
     6481 cctttctaaa atctgcattc atcaatcgtc tggagagtgt gctgagaatc tctagatgca
     6541 tatctgctga tttttcagga actacgatgg caaaaatata ttcaattggc atttcatcta
     6601 tcccgctata gtccgttaat ttggctgtat gaaaaaaaca cagtgctggt tttgtcacat
     6661 atttgctttt tgcatgggga atcccaaatc catcttctat tcctgtggag atctcctcct
     6721 ctcgtttgaa tagtgcctta acgacttttt gaacatttct taccttattt gtttttttca
     6781 acacatcccc tattcgctca aataatgatc cttttgaatc tatcgatgga tcgaaaacaa
     6841 tcagttcttc tgcgatcaat tgatcaaacc tcataaaaaa cctctccccc acaaaaaatg
     6901 ttaacgtttt cttggaactg aggtcagtat agcatcgcta gctgtaccgt tcaatattat
     6961 gaatgaacag aggaaaaaga cccatcatcc gcgtgtataa gtcattaaaa tgaacgatct
     7021 agctcacaaa caatcgcaag tctataacaa aacaaaaagc cttccttgaa aggaaagctt
     7081 agcttctaat tttaggtaaa tggtttttta cttcgaaata acccctcttc atttcgttaa
     7141 tataaggtgt ttttatcaag tggataatta aaactatata ctagtttttc attgttttgt
     7201 gcattatgat cctacgactt tttcagcatc aaacgaagtt ttaaattggc aaaaaacata
     7261 aaaaaacaga ctatccctat cagatagtct gctaaacgtt gagttatcag cgtttttatt
     7321 attccgcagc gtttgcgtct ttgagaccgt attttttgtt gaaacggtcc acacgtccgt
     7381 ctgcttgtgt gaatttttga cgtccagtgt agaatggatg tgagtcagaa gttacttcga
     7441 cacggatgac tgggtatgta ttaccgtctt cccattcaac tgtttcttgt gaagtttttg
     7501 ttgaacctga caagaatttg aaaccagttg ttgaatccat gaatactact gggtggtaat
     7561 ctggatggat gttttctttc atgatttttt cgctcctttg ccctgctcca tttgctgaac
     7621 cagagttgat ttgtcgattt acaacattaa catcttaaca tgtttcagtc aaggttgcaa
     7681 ttatcttttc agatttctgg tcggattttt tttaccaaag gagacatctt gaaattcttt
     7741 gaaaaattgc tgattgtttt ttgttttacg caaaaagcgg atcagttgtt ccgtatattc
     7801 taatgaatct ccagtcatat tttttcgaag tttccaaatt tcttctaatt cttcacttgg
     7861 catcaataat tcttcttttc gggtacctga ttttttgata tcgatggctg ggaagatccg
     7921 acgttcagat aattcacgtg aaagttgtaa ttctagattt ccagttcctt tgaattcttc
     7981 atagatcacg tcatccatac ggcttcctgt atcgactaaa gcggtcgcta aaatcgtcaa
     8041 actgccacct tcttcgatgt ttcttgctgc cccgaaaaat ttcttaggtt tatacaatgc
     8101 ggctgggtca atcccgccac tcaatgtacg tccgcttggt ggaacgacta agttataggc
     8161 ccgagcaagt ctagtaatac tatccatcaa gataacgaca tctcgtttat cttcgactaa
     8221 acgcattgcg cgttccaata ctaattcaga aactcgagta tggttttgcg gctgcagatc
     8281 aaatgtagaa gataccacgt cgcctttcac gcttcgttct agatccgtta cttcttccgg
     8341 tcgttcatca atcagtagaa cgattaattc tacttccgga tagttttcgg tgataccatt
     8401 tgcgatttct tttaatacag aagttttccc tgcttttggc ggtgcgacga tcaatccacg
     8461 ctgaccaaaa ccgattggag aaaagatatc gatcattcgg gtagatagtc tttgcggtgt
     8521 tgtttccagt tgaagctgtc tttgcggata aagaggtgtt aaggctggaa aatgcggacg
     8581 ttcttttgct tcttccggat cttttccatt aacgctttcc acgtgcatca aaccataata
     8641 acgttccgat tctttaggtg gacgggcttt tcctgccact ttgtccccat ttctcaaact
     8701 gaatcgtctg atttgtgagg cagaaatata gatatcttct gcacttggtc cataattgat
     8761 tggccgtaaa aaaccgtaac catcttgacc aacgatatcc aatattcctt ccatataata
     8821 aaatccttgt ttctctgctt gtgcacgaat cacagctaga gataattcct ttttattcat
     8881 cttactgtaa taaggaattt taaattcttt ggcataacta taaacttctt ttaacgtttt
     8941 gttctctagt tctgccattg tcaaataatc gctcattcag ctcccacttc ctctatcatt
     9001 tcaattgatg cccctaaggc tgttagtttc tcgataatat gatcataacc gcgtaagata
     9061 taatctacat tgtaaatcgt cgttgtccct tctgccaata gtccagcaat cactaaacaa
     9121 gcacctgccc gaagatcaga agccacgact tctgtgccgt gaagtttatt tggaccattc
     9181 acgatgatca tatttccttc cacggtaata tcagcgccca ttcgtgctag ttccggcaca
     9241 tggttcacac gtttcgcata gatcgtatcg atgatttctg aagtgcctgt agtcatcaat
     9301 agtaacgcag taagtggctg ctgcagatct gtggcaaatc ctggataagg ataggtcatg
     9361 atgtttgcgg gttttaattc tttcgagggg taaacttcga tttcatcttc gctgattttc
     9421 atatggacac caatttcctg caattttgct ataaagcttt ccaaatgttc aaagatcaca
     9481 tttttcactt tgataccatt tcctactgca gctgctaatg ctagataggt tcctgcttcg
     9541 atgcggtcag gaatcatgaa atgccgacag ccatgtaatg tttcgactcc ttcgatacgg
     9601 atcacatctg tacccgctcc tcgaactttt gcccccatat tattcagtaa agttgccaca
     9661 tctatgattt ccggttctcg tgcagcgttt tcaattactg tctgtccttt tgcttttaca
     9721 gcagctaaca tcacattgat cgttgctccg actgaaacca cgtccatgaa aatccgattg
     9781 ccacgcaatc ctttattttc tgtccgtaaa tacatggcac catgttcatt tgtcacttca
     9841 gcacctagag cttcaaatcc tttgacgtgt aggtcaatcg gtctagggcc taaataacag
     9901 ccacctggca ggcctactac cgcttcgcca aatttaccaa gcagtgttcc cataaaataa
     9961 taagaagcac gcaaactatt gatttttccg tgcggcatcg gaatcgatac gacttctcga
    10021 ggatcgattt ctagtatgtt gttggaaaaa tggacagttg cgcccatgat ctctaaaatt
    10081 tcaattaatg aatgaacatc ttgtatgtcc ggcacacctt ccaagatcac tggggaatca
    10141 gctaagattg cagctggaat caatgcgact gcactatttt ttgcaccgct gatcgttact
    10201 tcaccagcta aaggtcggtt tcctttgatt acgatttttt tcatctgttt ccaccttgtt
    10261 tattaatctt ttttcatgga tatgcttgta ttttatcata gataaaaaaa agaaacgagc
    10321 atggtctgcc gttttaagta aaaaagaatg gagagcgact tcaaaagtcg ttctccattc
    10381 ctatatatcg tatctgttat gtggatgctt acgctttgtt agctgaaccg aaccagtcga
    10441 tatgagattt agcatcttca acgattgctg ctttacctgg agctaataat ttacgagggt
    10501 cgaatccttt accttcttta tctttaccag cttcgatata tttacgagta gctgcagcaa
    10561 atgataattg gaattcagtg ttaacattta cttttgagat acccattgag atagcttttt
    10621 cgatttgatc ttgaggaata cctgatccgc catgtaatac taaaggcatg tctggaccta
    10681 cagcatcagc aattgcttgt aagtggtcaa aagctaatcc tttccagttt tctggatatt
    10741 gaccatggat gttaccgata ccgcaagcta agtagtcgat acctgtagca accatttgtt
    10801 tgcattcttc aatatcagct aattcgccgt taccgatgat tccgtcttct tctccgccga
    10861 ttgaaccaac ttcacattca actgagatac cttttgcatg tgctttttca acaacgtctt
    10921 tagctaattt caagttttct tcaaatggta gatgtgaacc atcgaacatt actgaagtat
    10981 agcctaattc gatacattcc aaagcagctt cgtaatcacc atggtctaag tggatagcaa
    11041 ctggaacagt gatgttcatt gcttcaacta aatcagtgat taaatcttta cagattttgt
    11101 aaccacccat gtatttagct gcacccattg atgtttggat aagtactggt gcttgttttg
    11161 cttcagccgc ttcaaggatt gcttgagtcc attccaagtt gtttgtgttg aatccgccga
    11221 cagcgtaacc gcctttacga gcagctttta aaaattcagc tcctgatact actggcataa
    11281 taaaattcct cctaagtttt gtaaaactaa atttgttaag acaattctta accaacgacc
    11341 ctattttacc aaacatttcg gtagttttct actaaaatca atgaaaatga aaattttcaa
    11401 gaagtttttt gcaaaaaata aaatatccaa tagcgcttta atcgaaaaaa gtcttttgct
    11461 ttctatcttt tttcctacaa ataataacaa atcagaaaaa gagaaaagtg acaagaaaat
    11521 tgcttatccc cttctcttgc tacttttctc tttctatcaa gttcaaaaat tattttgttt
    11581 cgtgatctgc taatgatgct ccgacaaatg ctttgattaa tttttgcggg cgatttggac
    11641 gagaaatcaa ttctgggtgg aattggcatc ccacaaagaa ttttttctct ggcagctcta
    11701 cgatttctac taaacggtta tctggtgaga cacctgaaaa gactagccct tgttcttcaa
    11761 acaattgacg atatttgtta ttgaactcat agcggtgacg gtgacgttct tgcacaacat
    11821 cggctccatc atatgcttca gccgtcttcg ttcctttttt gattttacat gggtataatc
    11881 caaggcgtaa agttccaccc aaattctcga tgttttcctg atcagccatt aaatcaataa
    11941 tattgtttgc tgtatctgga ttcgtttcag ctgatgacgc atcttctaat ccaacgacgt
    12001 tacgtgcaaa ttcgacacaa gccatctgca taccaagaca aatacctaaa aacggaacgt
    12061 cattttcgcg agcataacga atcgcttcga ttttcccttc tactccgcga tcaccaaatc
    12121 caccaggaac caagattcca tctgcgtctt tcaaacgttc ttctacattt tctctcgtta
    12181 attcttgtgc tttgatccaa tcgatctcga tgtctgaatt ataggcgaaa ccagaatgtt
    12241 tcaatgcttc aactactgag atatatgcat ctggtaactc gacatattta ccgacaagcg
    12301 caatccgtac ttttttcttc aagttcaaga cacgttcttc taattctttc cattctgtca
    12361 tgtctgcttc tggtgtatct agttttaaat ggtcgcaaac aatttgatcc attccttgtg
    12421 cttgtaaaac taatgggatg gagtaaagtg tatctacatc tggcgactcg ataactgctt
    12481 ctggttcgac atcacaaaat tgtgccaatt tgtttttcac gctttgagaa acaggttgct
    12541 ctgtacgtac caccaaaata ttcggttgga tacctaaacc acgtagctct tttacactgt
    12601 gctgcgttgg tttagttttc atttctccag cagctttcaa gtaaggaatc aatgttgtat
    12661 ggatatacat aacattatct gtaccgacat ctgctttcat ttgacgaagt gcttcaagga
    12721 atggcaaaga ttctatatcc cctactgttc cccctacttc tgtaatgatc acatctgaat
    12781 cagtcatttt agctgctcgc atgatttttt ctttgatctc atttgtaata tgaggaataa
    12841 cttgaacagt tgctcccaag tattcgccct tacgttcttt acgcaaaact tcagaataga
    12901 tttttcctgt cgtcacgttg gagtatttgt tcaaattgat gtcaataaaa cgttcgtagt
    12961 ggcccagatc caaatctgtt tcagcaccat catctgttac gaatacttct ccgtgctgat
    13021 atgggctcat cgtccccgga tccacgttga tgtatggatc aaatttttgg atagttactt
    13081 ttaagccgcg gtttttcaat aagcgtccta aagaagctgc aacaatccct tttccgattg
    13141 atgaaacgac accgccggtc acaaaaatat attttgtcat aagttcaaaa actccttttt
    13201 aatttatgtg caggaaaagt ctcagacaat aaacaaagct ccctattctt caataagaat
    13261 agggagccga aatttctgta aacttctgac cctctaaaag ggtgcccaag gtgtataata
    13321 caagctgact aagggaaagt caagtactca aatgaatact atccgcttac aattttttct
    13381 ttttcgatat cctttgagaa attatttctt aagtccttta tgagtgcaaa aaaaatttaa
    13441 cccacataat aagcttgata taaacatagc taacgttaaa cctaagcaaa tcagaaaatc
    13501 gttactgaaa aattttaagt gaaataatag ataaaaaaat aaaacaaaca ttatgataga
    13561 taatatccca cctaacaaag aactactttt tcctacttgc agcaacagtt tatatagctt
    13621 atcgtagaaa caatcttttt ctttcaccct tatttacctc ctttacgtaa aaaacgtagt
    13681 ccacagttct cggatttttg gcatatcttt tctattaaat aatatcaaaa acaaaacaat
    13741 tccactaatt ttttcaaaga tgaccttttt ttcaacaaaa gtgccttgta gggattcatt
    13801 gaaggtaacg aatcacataa gtaaaaaata aggagatgcg acaaaagtcg tgcctcctta
    13861 tttctaaata aacggtgttc tcctgccaac tcctcggtca caagtcacaa tatccatcaa
    13921 acatgagaag ctgtttttga aattatttct tgtgattcgg agttaaatgg taggctcaca
    13981 acctctggat aaacggtatt caaaagccag tttctcggta ttaagccaaa tttatgcaaa
    14041 aatgtagaaa gccattttca caaaattttt cttaatactc gaaactaaac gtctttttca
    14101 aaacctcttg gtaaacggtg ttcaaaagct tgcatctgcg gtaataagtt cagccaattc
    14161 aaaaacaaga aaagctgttt ttgcttggct attcttatta cttgttgcag ggcagctttt
    14221 tcacaacctc tccactaaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac
    14281 ggcaaaatat gaggaactat ttttccgtta gtttctctaa tactcaggtc aaaacgctga
    14341 tttcacagcc tctaattcac ggtattcctg ttttaataaa gttctagata ttgttctctt
    14401 tcccactcgg aaacagtttg tctgaatgcc gcccattcga gacgttttgc ttcaacaaaa
    14461 tttgagaaga tatgttgtcc taatgcgtca atcattacat tatccttacg caattctttg
    14521 atagcattat ggatagttga aggtaagtcc tggatatgtg cagcttctct ttcttcctca
    14581 tccattacat aaatgttacg gtcaacagct gctggcggtg tgatctgatt acggataccg
    14641 tctagtcctg cttgcaacaa tactgccatt gccaagtatg ggtttgcaga tggatcaact
    14701 gaccgcaatt ccaaacgtgt ggataaaccg cgagattctg gtacacgtac taatggcgaa
    14761 cgattacggc cactccatgc gacataaaca ggcgcttcat aacctggaac gagacgttta
    14821 taagaattga ctgttggatt gcaaacggct gtgtaggcac gagcatgttt cagcaaacca
    14881 cctaagaaat gataagctgt ttcacttagt tccaattcac cgtctttatc atagaaaaca
    14941 tttccttcat cattgaacaa agacatattg caatgcatac cagaaccatt gatcccaaat
    15001 aacggtttcg gcatgaaagt cgcgtgaagt ccatgcttgc gtgcaatcgt tttgacaacg
    15061 agcttgaagg tttggatatt atcacaagca tctaccacat ctgcatattt aaagtcaatt
    15121 tcatgctgtc ctggcgctac ttcatgatgt gaagcttcca cttcaaagcc tagactttct
    15181 aattccaaca cgatgtcacg gcggcaattt tcacctaaat ctgttggtgc aaaatcaaaa
    15241 taaccacctt tatcattcaa ggtcgttgtg atcccaccgt cttcgtctaa tttaaataag
    15301 aagaattctg gttcaggtcc taaattgaaa gaggtaaaac caaggtcgcg catatctttc
    15361 aatgctcgtt tcaaattccc gcgaggatcg ccggcaaatg gtgtcccatc cggattatag
    15421 atatcacaaa ttaaacgagc aacttttcca tgagcacttt cccacgggaa gatcatccaa
    15481 gtggagagat ctggatacaa atacatatcg ctttcttcaa ttcgaacaaa tccttcaatc
    15541 gaagaaccgt caaacatcat tttattttct aatactttgt cgatctggct cactggaact
    15601 tctacatttt tgatcgtacc taagatgtct gtgaacatca atcgtaaaaa tcgtacgttt
    15661 tcttcctcaa tgattcgttt gatttcttca cctgttatct gtttctttac catggtatcc
    15721 ctcttccttt tttaatttat tcagtcaaag aattgtcttt gcaatccttg cgactgataa
    15781 tgacctgttt tgcttaaccc accttgcgcc aaaatctcat cacgaaaaat ttgtcgaacg
    15841 tcatgatctg tcaacggctt cttgtttttt gcttcttgtt ttttcgcctg tgccatttcg
    15901 tatacacgtt tgatcccagc catattcaat ccctctgaaa gatagtcttt aatctcaagc
    15961 aacatatcaa tatcattcag cgaatacata cgtcggtttc cttcgcttcg ttccggatga
    16021 actaaatctt gttcttcata atagcgaatt tgccgagcag acaaatcagt cagcttcata
    16081 actgtaccaa ttggaaatac ggacatagat cggcgcaatt ccttttctcc catcagacgt
    16141 cccctttcgt tttataagtt ggctaaagtg taccaattaa aaaaaatatt gtcaactgca
    16201 tatgttaggt tttctaacat gagatctcta ttttttataa aataacaaaa aaataagaac
    16261 acaaaaaagg tatctagttg attttcgtac cagatacctt ttatttttta ttatactgta
    16321 ctatccttta ttagtgtttt tatt
//
LOCUS       DBBGSP010000063        15950 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000063 DBBGSP010000000
VERSION     DBBGSP010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.063"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..450)
                     /locus_tag="ACIZE9_002442"
     CDS             complement(<1..450)
                     /locus_tag="ACIZE9_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6094261.1"
                     /translation="MKYKEMFVPSLIQLAVEVKNKEEAFLIAAQQLEKMGYVNENYLN
                     GLIAREREFPTGLITKYLNIALPHSECEYVEKPFVFVMQLKNPIYFYQMGDNQEMTVE
                     NLFFLGIKEPKEQVGLLQAFMNLFMDETFVENYKKQETPQNIYELITN"
     gene            674..1465
                     /locus_tag="ACIZE9_002443"
     CDS             674..1465
                     /locus_tag="ACIZE9_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGC6094262.1"
                     /translation="MLKKERQEQIITLLEKDFYLTNSEIANKLGVSEMTIRRDVTELA
                     KKNKVKKLYGGVERKEPYNRELSTQEKIDTNVAEKKYIGQVMNSMIPDNSTIYVGAGT
                     TILYALPFIQKKNLFVITNSLIAFNYLKNHTSYRILLTGGEFSPITEEFIGEVAERSF
                     ESLNVDISFAATNGIFDNNVTTAQFIEGNIQNAALNAAKIKCIVADYSKLNKSDVYTF
                     RKLTDFDYLITDNHLSEQDFNHYSKYLTILKEPKNDTDNHDEPIH"
     gene            1431..2384
                     /locus_tag="ACIZE9_002444"
     CDS             1431..2384
                     /locus_tag="ACIZE9_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HGC6094263.1"
                     /translation="MILTITMNPSIDSIYFTKHFELGTMTRFDSPVRYVGGKGINCGR
                     ASALLGSSVILTGFLGGYFGSMIQDMLKNENLFDLHFLPIAEESRGAVTIMHDDETQT
                     ELVEAGPEIADTTIKKLMNDIKLISKNNYLSVITINGSVNNPDPFLYAKLLQYIKEQI
                     DPSTYILMDISGQHLREVLASKYKPMFIKPNIHEFSDIIHQKITQKSDIKHHLKTNPL
                     FKDIDVIMISCGSYGAVVKVKEEFWNVEIPKIPIINTTGSGDATVGGFAHSLEQNYPL
                     KECVRYAMACGMSNAQQSEVGKVIPADVKNLAKSIKITEMK"
     gene            complement(2782..3756)
                     /locus_tag="ACIZE9_002445"
     CDS             complement(2782..3756)
                     /locus_tag="ACIZE9_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6094264.1"
                     /translation="MNKELNITQEWDKVFPKSNQVNHRKVSFPNRFGITLVADLYEPK
                     EVSEKKLPAIAVSGPFGAVKEQSSGLYAQTMAERGFLTIAFDPSFTGESGGVPRYVAS
                     PDINTEDFQAAVDFLSVQKNVNPERIGIIGICGWGGMALNAAAIDTRVKATVVSTMYD
                     MTRVTANGYFDVMDENARYEMREELNAQRIIDFKQGDYARAGGVVDPLPEDAPQFVKD
                     YHAYYKTDRGYHVRSLNSNDGWNRTSGLSLMNAKLLHYIPEIRHAVLVIHGEKAHSRY
                     FGEDAFKELKGDNKELMIIPGASHTDLYDQTDIIPFEKMATFFEENLV"
     gene            3871..4305
                     /locus_tag="ACIZE9_002446"
     CDS             3871..4305
                     /locus_tag="ACIZE9_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC6094265.1"
                     /translation="MYSIGQVSEMFGLPVSTLRYYDKEGLFPDIQRVSGIRKFSENEL
                     EALRVIDCLKKSGLEIKDIKQFMEWSKEGSKTFEVRKELFEKQKEVVEKEIAKLERVL
                     AMLNYKSWYYEEAIKAGNEEAVLTMIPDDLPQHVKEAYVHSH"
     gene            complement(4430..5452)
                     /locus_tag="ACIZE9_002447"
     CDS             complement(4430..5452)
                     /locus_tag="ACIZE9_002447"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGC6094266.1"
                     /translation="MKKIGFLSFGHWMEQGSLVKSAQDAYLQSIDLAVEAEKIGVDGA
                     FFRVHHFAPQIGSPFPLLAAIGAKTSKIEIGTGLIDMRYENPYYMAENAGLTDIITQG
                     RVQLGVGRGSPEQVLDGWKYFGYDYSEEEIKEVTRERTLEFLELLEGKPFEEPNPQPM
                     FPQGSGKLRIEPYSEGLRQRIWWGAGSQQTAIWAAQHGMNLQSSTLVNYESHEPFHIQ
                     QANQLRAYKEAWKQAGHDFEPRTLVTRSIQPITTDLDRRLFGQDGSPQQDAVGYLAYH
                     RNPTIFGKTFAGEPDQLIKELAEDEAIKEADTVLVTIPNTLGVEYNMHLLETIVKDIA
                     PELGWR"
     gene            5844..6266
                     /gene="arsC"
                     /locus_tag="ACIZE9_002448"
     CDS             5844..6266
                     /gene="arsC"
                     /locus_tag="ACIZE9_002448"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030612 - arsenate reductase (thioredoxin)
                     activity [Evidence IEA];
                     GO_process: GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HGC6094267.1"
                     /translation="MKKIYFLCTGNSCRSQIAEGYARKYLSPSMFEIRSAGIETHGLN
                     PRAIKIMAEDGIDISKQTSDLIDRDYFTQADLIITLCGDAKDKCPAVPNNHEHLHWDL
                     KDPAQAVGSEEEILTEFRKVREGIKRKVLDLNQRTSIV"
     gene            complement(6546..8468)
                     /locus_tag="ACIZE9_002449"
     CDS             complement(6546..8468)
                     /locus_tag="ACIZE9_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC6094268.1"
                     /translation="MNQRQQSLIYQLSENNNYITTKKLAEHFHVSERTIHSDLNTIET
                     WLRDKHLPLMFERKKGTGILLNGLPHEREQLKRALNEETQTEMDKKQLRQLLIFHLLV
                     AKDGFSLEELSEKLYVGKRTIRKELTELQSFFEYHHLQLVSKTKLGTFLKGDEQEKRQ
                     LLVKTLRNMQKEDPQSPSLKEFFAKDTLKVIQHTLQDVFYENHLEQPNGLASVEIHIY
                     FMLERMKQYQKVKLSKDENEVVEHTQAQKLSSQILAKLATIYPIEFSPDEINYLALRI
                     ANLFTNSQAATRFQKESSALADHLIEQVEQFLGYSLKEDQLLKQNLRSHLSSTYFRLH
                     YGLQISNPLTKNVFSTYTQLFLVLQLILEDYFEKENFYVPQEETAYLTIHFQAAIERH
                     KHQKSRRYQTVLVSEYSKAMATFLEARLNRELPELTIMDLVEYKPELKRQDFPSVDFI
                     LATLPFKHISIPVIEISPMITETDLAYLTKYMLEHVPIKKKKTFDLASFTHPFLIFPQ
                     LERTDPADILNFMGNVLVEHHYVEPEFIDSVLERDSHSSTRVAPFVTIPHGNPLYVKH
                     SMISIATMKEPVLWHGEQIRIVLLLAIKKNDLKHAEFKKIFSVIHYLEKQPEQMAQLM
                     QSNHPLEILTLLSSYE"
     gene            complement(8555..10495)
                     /locus_tag="ACIZE9_002450"
     CDS             complement(8555..10495)
                     /locus_tag="ACIZE9_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGC6094269.1"
                     /translation="MKKIIAITSCPVGIAHTYMAAENLEKAGKAVGAEVKVETHGSIG
                     IENELTARDIEEAAGVIIAADTKIDKSRFGGKPLITVGVQEGIHHADELVRDILAGKA
                     PVYKSTEAIISSENKSESENLGKKIYKSLMNGVSYMVPFVVTGGLLIAISLTLGGTAT
                     PEGIKIPEGTIWATMNSIGSIAMGLMVPILSAFIAQSIADRPGLVPGFVGGMLAANGA
                     LYGSDANAGFLGGIITGFLAGFIALGIKKVRVPKALQSIMPIIVIPILGSLAVGFVFI
                     YVIGEPVALLFSSLTHFLAGMQGGSEIVLAMILGAMIAFDMGGPFNKVAFLFGSGLIA
                     EGNYSIMGPIAVAICIPPLALGLASLILKTKFTKTEREAGKASLAMGLFGITEGAIPF
                     ASTDPLRVIPSIVIGAMTGSVIAMLSGVTDHVAHGGPIVAVLGAVDHVAMFFVAVIAG
                     IAVTVLMLRILKPTLQQTAVAAANGVTVADLSETETSDVYTKTETFDSITDIMSDEAI
                     VLGETATTKDGVIEDLVQRLEKTAAITDKTRFKEVIYDREHESTTGIGMGIAIPHGKS
                     AYVLKPTVAFARSQSGVDWHSLDGKPAHMIFMIAVPENSQGDMHLKILQRLSRKLMDD
                     DFRQALMEAPDKTTVHQLLSEM"
     gene            complement(10783..11523)
                     /locus_tag="ACIZE9_002451"
     CDS             complement(10783..11523)
                     /locus_tag="ACIZE9_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HGC6094270.1"
                     /translation="MSVIPNYYKNRVCLNVLAHSVENAKACYEAAEGHVVLGVLSKNY
                     ASDEAAIEDMKRYQDATNNALSVGLGAGDPNQSQMVSRLSGVLQPQHVNQVFTGVGTS
                     RALLGQNDTVINGLVSPTGKIGYVNIATGPLSSQAPAAEVPIETAIQMLQDMGGTSIK
                     YFPMKGLAHREEFKAVAEACAKYEFYLEPTGGIDLSNFEEILKIAIDAGVKKVIPHVY
                     SSIIDKETGDTRIGDVKILLSMVKKIIH"
     gene            complement(11536..12627)
                     /locus_tag="ACIZE9_002452"
     CDS             complement(11536..12627)
                     /locus_tag="ACIZE9_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HGC6094271.1"
                     /translation="MTISYGKFDLKEVINASGKMTILGVSKVSESVLAAQRFGGEHFF
                     EMSDLAIKTGAYLSQLLKVEDAQIVSSASAGIAQSVAALIGQGDMYHVYHPYTEKIAR
                     REIIIPKGHNVDYGTPVEVMVAQGGGKVIEAGYANMCTPEHVSMMITEKTAALLYIKS
                     HHAVQKSMLTVAEMVEVAKAHRLPLIVDAAAEEDLFKYSEMGVDLVIYSGAKAIEGPS
                     AGLVIGKKKYIQWIRLQSKGIGRAMKIGKDNILGFTQALEDYLKNGSESGDSMKQRLA
                     PFVNAINQLPDLSAKIVQDGAGRDIYRASVTINGDKSAKEVIQELKARNPAVYTREYQ
                     ANNGIIEFDIRSVSQNEMEKIIKRLREIM"
     gene            complement(12617..13723)
                     /locus_tag="ACIZE9_002453"
     CDS             complement(12617..13723)
                     /locus_tag="ACIZE9_002453"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HGC6094272.1"
                     /translation="MFDTLIKNGRLVDGSKIEVAIEKGMIKAVAAEINQPAQEVVDLE
                     GKYYLSAGWIDDHVHCYEKMNLYYDYPDQIGVEKGVTTVIDAGTTGAENIREFYQLTK
                     SVKTNVYALMNISKWGIVKQDELADLTKIQEDLVSTALAELPEFIVGIKARMSKTVVG
                     ENGIKPLELAKKIQTENNDLPLMVHIGSAPPELEEVLSRMERGDVLTHCFNGKPNGIL
                     DPKTDQIKNFVWDAYNNGVVFDIGHGTDSFNFHVAETALKAGMKATSISTDIYIRNRT
                     NGPVFDLATTLEKLRVVGYSWEEIIEKVTAVPARNFHLKNKGQLAVNYDADLTIFEIV
                     ENEKELKDSNGFTRIAKEQILPIKTIIGGVIYDN"
     gene            complement(13742..14404)
                     /locus_tag="ACIZE9_002454"
     CDS             complement(13742..14404)
                     /locus_tag="ACIZE9_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HGC6094273.1"
                     /translation="METTEEQAKVLEAKRQKSFWFADWSFPLIVGIMSAAVFAGTHMY
                     VMYGVGAFNEVSIVAMLKAGLDGGSYGAAAAFGASFLFARILEGSLVGILDLGGSILT
                     GIGIGVPAILLSMKIAAPIDNFALSLLTGLVLGLIVGGIIVLIRKFTINQSNSTFGAD
                     VMMGAGNSSGRFLGPLIILSACAASIPIGIGATLGALGFYAWKKPIAGGAILGAIFPA
                     VN"
     gene            complement(14415..15194)
                     /locus_tag="ACIZE9_002455"
     CDS             complement(14415..15194)
                     /locus_tag="ACIZE9_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HGC6094274.1"
                     /translation="MDFVIILVKSVIIGGLLGFAASVGAARMFHAPNTQGLGAFRTLG
                     EMNACMGDPASHFSFGLGFFFNAWASSVGAGAFTQDVTHRIIPNWAAAALLAKNKDVT
                     QTMHDPKKMGIIGAVIGAVVVAFLNTTAAAIPEALQVTAVSVLVPAATILINTVMPVI
                     FWLAALDAGKRTGFWGTLFGGIAQLIMGNAVPGVVLGILIGKGVDESGWNRVTKSMMI
                     AIVLLFIFSGFFRGFDMEMIKSFQLQVPNWLDNLHNIFSVK"
     gene            complement(15223..15573)
                     /locus_tag="ACIZE9_002456"
     CDS             complement(15223..15573)
                     /locus_tag="ACIZE9_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HGC6094275.1"
                     /translation="MSVQKTIQQKVIVSGKGETKQHAFASALAEIQNKIMEQSNVLLR
                     IEPVNVDILKAVENKYTERFLFFFFPRQRISYEVELSVTVAVTEIKLADISFSQQMTE
                     DPNGIAIPFVTKKI"
     gene            complement(15589..15945)
                     /locus_tag="ACIZE9_002457"
     CDS             complement(15589..15945)
                     /locus_tag="ACIZE9_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich SFCGS family protein"
                     /protein_id="HGC6094276.1"
                     /translation="MIKVVIADRMGKGQNVAKGVEAAGGKAVVVPGMGADMRLGDVMQ
                     QEHADMGISFCGSGGAGALTAATKYGYPERHGMRSIEEGITAIKDGKTVLGFGFMDQE
                     ELGKRLTEEFIKKHGK"
BASE COUNT         4733 a         3340 c         2689 g         5188 t
ORIGIN      
        1 atttgtaata agttcgtata tgttttgcgg tgtttcttgt ttcttgtaat tttccacgaa
       61 tgtttcatcc atgaataaat tcataaacgc ttgaagtaat cctacttgtt cttttggttc
      121 tttgattcct aaaaaaaata gattttctac agtcatttcc tgattatccc ccatttgata
      181 aaaataaatt gggttcttca gctgcataac aaaaacaaat ggcttttcga catattcaca
      241 ttccgaatgt ggcagcgcga tatttaaata cttagtaatc aatccagtag gaaattctct
      301 ttctcttgca atcagtccat tcaaataatt ctcattgacg taccccattt tttctaattg
      361 ttgtgcagcg attaaaaaag cttcttcttt attttttact tctaccgcta attgaatcaa
      421 actaggaacg aacatctctt tatatttcat tccaacctcc tcctttttga ttaagtttgt
      481 taatttattg ttctactaaa ttcatctttg ttttacaaga acattatatt tctgttagtt
      541 tgttttgtca acgctttcaa aagaaattta ttttgttaaa tttgatctac ttgaaaataa
      601 aatcgtttat ctatataatt aagaagaaca aagtcgaaca aaaattgact tttatgttaa
      661 aggagtaatt catatgctga aaaaagaaag acaagaacaa atcattacat tattagagaa
      721 agatttttat ttaactaatt cagaaatcgc taacaaatta ggcgtatcag aaatgaccat
      781 acgccgagat gtcactgaat tagcaaaaaa aaataaagta aaaaagctat atggtggcgt
      841 tgaacgaaag gaaccttata atcgagaact atcgactcaa gaaaagattg atacgaatgt
      901 agccgaaaaa aaatatattg gtcaagtcat gaacagtatg attcccgata attctactat
      961 ttatgtcggt gctggaacaa cgatcctata tgcacttcct ttcattcaaa agaaaaatct
     1021 atttgtaatt acaaacagtt tgattgcttt caactattta aagaatcata caagttatcg
     1081 gattttactt actggtggcg aattttctcc tattacagaa gagttcattg gggaagttgc
     1141 agaaagatct tttgaaagtt tgaatgtcga tatctctttc gctgcaacaa acggcatatt
     1201 tgataacaat gtgacaaccg ctcaatttat tgagggaaat attcagaacg cagcgctcaa
     1261 tgcagcaaaa atcaaatgca ttgttgcaga ttattcaaaa ttaaataaat cagacgtcta
     1321 tacttttaga aaattaaccg attttgatta tctaataacc gataatcatt tatcagaaca
     1381 ggatttcaat cattattcaa aatacttaac aatattaaag gagcccaaaa atgatactga
     1441 caatcacgat gaacccatcc attgattcca tttattttac aaaacacttt gaattaggta
     1501 cgatgacacg ctttgattct ccggtacgct atgtaggcgg caagggaatc aattgcggac
     1561 gagcttctgc tctactaggt tcatcagtta ttttaacagg gtttttgggc ggttattttg
     1621 gcagtatgat tcaagatatg ctgaaaaatg aaaatttgtt tgatttgcat tttttaccta
     1681 ttgcagaaga atcaagaggt gccgtcacga tcatgcatga tgatgaaacg cagacagagc
     1741 tagtggaagc tggtcctgaa atagcagata ctactatcaa aaaattaatg aatgatatca
     1801 aactaatcag taaaaataat tacctttcag tcattacaat aaatggttct gttaacaatc
     1861 cagatccctt tttgtatgct aaattattac aatatatcaa agaacaaata gatccttcca
     1921 cctatatatt aatggatata tctggacaac atctccgtga agtcttagca agtaagtata
     1981 aaccgatgtt catcaaacct aatatccatg agttttcaga tatcatccat caaaaaatta
     2041 ctcaaaaaag cgacataaaa caccatctaa aaacaaatcc actatttaaa gatatcgatg
     2101 ttatcatgat ttcttgcggc tcgtatggtg cagtagtcaa agtaaaagaa gaattttgga
     2161 atgttgagat ccctaagatt cctatcatta atacaacagg ctctggggat gccactgttg
     2221 gaggttttgc tcattcatta gaacagaatt atcctttaaa agaatgtgta aggtacgcaa
     2281 tggcttgcgg catgtcgaat gcacagcaat cagaagtcgg gaaagttatt ccagctgatg
     2341 taaaaaattt agcaaaaagc attaaaatca cagaaatgaa ataaatagta caaagtaaat
     2401 aattgtttat atgaaatgag acacaaagag actgtgacaa aaaacgtgtg taccgacccc
     2461 caaaagttag attttttggt ctaacttttg ggagtcgata cattgtcaca gtcctttttt
     2521 cgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
     2581 gagaagctat tttttgaaat tgctccttgt gactcagagt taaacggcag gctcacgacc
     2641 tcttggtata aacggtgttc aaaagcttgc atctacgcta atgagtccaa ccaagtcaaa
     2701 aatgaggagc ttttttggct gtccttatta cttgatgcag ggcagttttt tcataatctc
     2761 ttttagatta aatccttttg gttacacaag gttctcttca aagaatgttg ccattttttc
     2821 aaatggaatg atgtctgtct ggtcgtatag atctgtatgg gatgctcctg gaatgatcat
     2881 gagttccttg ttgtcacctt ttagttcttt gaaagcgtcc tccccaaagt aacgtgaatg
     2941 agctttttcc ccgtgaatga ctaagactgc atgacggatt tctggaatat aatgcaatag
     3001 ttttgcattc ataagtgaca accctgatgt cctattccaa ccatcattgg agtttaaaga
     3061 acggacatga tatccgcggt ctgttttata atacgcatga tagtctttga caaattgagg
     3121 agcatcttca ggcaacggat caaccacacc tccagcacgt gcgtagtccc cttgtttgaa
     3181 atcaatgatg cgttgtgcat ttaattcttc acgcatttca tatcgggcat tttcatccat
     3241 aacatcgaag tagccatttg ctgttactcg agtcatgtca tacattgtgg aaacaactgt
     3301 tgctttgacc cgcgtatcga tagctgctgc attcaatgcc atacctcccc atccacaaat
     3361 accaatgatt ccgattctct cagggtttac atttttttgt acagataaaa agtctactgc
     3421 cgcttggaaa tcttccgtat tgatatcagg cgaagcaaca tatcgaggta ctcctccgct
     3481 ttctcctgta aacgatggat caaacgcaat cgttaaaaag cctctttcag ccatcgtctg
     3541 cgcatataga ccagacgatt gttccttcac tgcaccaaat ggcccgctca cagcgattgc
     3601 cggcaatttc ttttcactta cttcttttgg ttcatataaa tcagcgacta atgtgatacc
     3661 aaaacgattc gggaagctca cctttcgatg attgacttga ttgctttttg gaaatacttt
     3721 gtcccattct tgtgtgatgt ttaattcttt attcatattc tagactctcc tttgatcaaa
     3781 attgacattt gtttttgaat gtattattat gataaaactt aaacttgact ttaggtcaag
     3841 gtaaaaattt tattttagga ggattttttt atgtattcca ttggacaagt gtctgaaatg
     3901 tttggattgc ctgtttctac tttacgttat tacgacaaag agggattatt tcctgatatc
     3961 cagcgtgttt ctggtattag aaaattttca gagaatgagt tagaggcttt aagagtcatt
     4021 gactgtttga aaaaatctgg tttagaaata aaagacatta agcaattcat ggaatggagc
     4081 aaagaaggca gtaagacatt tgaggttcgt aaagaactat ttgaaaaaca aaaagaagta
     4141 gtagaaaaag aaatagcaaa attagaaaga gtactcgcta tgctaaacta caaaagctgg
     4201 tactatgaag aagcaataaa agccggcaat gaagaagccg tattgacaat gattcctgat
     4261 gatttacccc aacatgtaaa agaagcttat gtacattctc attgaacaaa cggataactc
     4321 actctccttc tctatgaact tcatgaaaac atgaataaac acctctaact gattgttaga
     4381 agtgtttatt ttttcactca agtatcctgc acttacaaaa atatcctttt taccgccatc
     4441 ctaattctgg agcgatatct tttacgattg tttcaagcaa gtgcatgtta tattctaccc
     4501 ccaaagtatt aggaatcgtg acaagtactg tgtctgcttc tttgattgct tcatcttcag
     4561 ctagctcctt gattaattga tcaggttcac cagcaaaagt ttttccaaaa atcgttgggt
     4621 ttcggtgata agcaagatag ccgacagcat cttgttgcgg actaccgtct tgtccaaata
     4681 agcgtcgatc caaatcagtg gtgattggct gaatcgagcg agtaactaat gttcttggtt
     4741 caaaatcatg acctgcttgc ttccacgctt ctttatacgc acgtaattgg tttgcttgtt
     4801 ggatatggaa tggctcgtgg gattcgtaat tgactaatgt agatgattgc agattcattc
     4861 catgttgtgc tgcccagatt gccgtttgct gcgaaccagc tccccaccag attctttgtc
     4921 gtaatccttc tgaataaggt tctatccgta attttcctga tccttgtggg aacattggtt
     4981 gaggatttgg ttcttcaaat ggttttcctt caagtaattc caagaattca agggtgcgtt
     5041 cccgtgttac ctctttgatt tcttcttcac tgtaatcata accaaagtat ttccagccat
     5101 ctagaacttg ttcaggtgaa ccacgcccca ctcctagttg cactcttcct tgcgtgatga
     5161 tatctgtcaa tccggcattt tctgccatat aataagggtt ttcatatcgc atatcaataa
     5221 gtcctgtacc gatttcaatc ttacttgtct ttgcgccgat tgccgctagc aaaggaaacg
     5281 gcgacccaat ctgaggggca aaatgatgta cgcggaaaaa cgctccgtcc actccgattt
     5341 tttctgcttc caccgctaaa tcaatcgatt gcaaataagc atcttgagct gatttcacaa
     5401 gcgatccttg ctccatccaa tgtccaaagc ttaaaaagcc gatttttttc aaggtaatga
     5461 cctcctttaa acctacaaaa atggaaggtt ttttattttt aatatgaact gattctacta
     5521 ctttttttct taaaagacga ataattgttc tcgcctcaca atcaagaaat gtatcggctt
     5581 actacacccc tactttcttc atcatctgcc gtgtcttaat ctcttttaac agtctgttac
     5641 atcgttgatt tttgactcaa aatgattgtt tctaacatgt atttatggta aaaaagacaa
     5701 gattagttct ttgtacacat cgatttatac gctgaacaaa aagaaatata taaactaaga
     5761 aacccattgt tttttcgctc catcacatag agtttacttt agataaacag tgacatttac
     5821 taatccataa cggaggaaat caaatgaaaa aaatctattt cttatgtacg ggcaattcat
     5881 gccgcagtca aatagcagaa ggctacgcgc gtaaatactt gtctccttca atgtttgaga
     5941 taagaagtgc ggggatcgag acacatggct tgaatccaag agctataaaa atcatggcag
     6001 aagacggcat cgatatttcc aaacagacgt ctgatttgat tgatagagat tactttactc
     6061 aggcagactt gatcattaca ctttgtggtg atgccaaaga caagtgccct gccgttccaa
     6121 acaatcacga acaccttcac tgggacctaa aagatcctgc acaagctgtc gggagcgaag
     6181 aagaaatatt aacggaattc agaaaagtca gagaaggaat caaaagaaaa gttttagact
     6241 taaatcaacg tacatcgatc gtataaagaa gtattcaaaa tgatttttca agcactaaga
     6301 aacaatgtta aaaaaatagc tttccatatt ttacaaaatt gtgccttatt gccgacaaat
     6361 tgtctcttga acaccgttta ccagtagtca agacatcgta agcaactata aaaaattata
     6421 agaaactcaa aataaaagga tgtgccacaa ctttggccac atcctctttt tttgtattta
     6481 gttttctact tccaaataaa tagatagaat tattataaat ataaaggcag ttttttaatc
     6541 gctacttatt cataactaga taacaacgtt aagatttcta gcggatgatt ggattgcatc
     6601 aactgagcca tttgttctgg ctgcttttct agatagtgaa taacagaaaa tatttttttg
     6661 aactctgcat gtttcaaatc atttttcttt attgctaata gcagtacgat acgtatctgt
     6721 tccccgtgcc ataggactgg ttctttcatt gtagcaatag aaatcatcga atgcttcaca
     6781 tacagcggat taccgtgagg gattgttaca aatggtgcta ctctagtact ggagtgactg
     6841 tctctttcca agacagaatc gatgaattcc ggctccacat aatgatgttc cactaagacg
     6901 tttcccataa agtttaaaat atcggctggg tctgtccgtt caagttgagg aaagatcaga
     6961 aatggatgag taaagcttgc tagatcaaat gtttttttct tcttgatagg cacatgctcc
     7021 agcatatatt ttgtcaaata ggctagatca gtttctgtga tcattggtga gatctcgatt
     7081 actggaatgc ttatatgttt aaatggtaac gtagccaaga taaaatcaac agagggaaaa
     7141 tcttgtctct ttaattctgg cttatattca actagatcca taatcgttaa ttctggaagt
     7201 tctctgttca gccgtgcttc gagaaaagta gccatagctt ttgaatattc actaactaaa
     7261 accgtttgat atcttctact tttctgatgt ttgtgtcgct cgatcgctgc ttggaaatgg
     7321 atcgttaaat aagctgtctc ctcttgtgga acataaaaat tttccttttc aaaataatct
     7381 tctaaaatta actgtaaaac taagaaaagt tgtgtgtacg tactaaacac atttttcgtc
     7441 aatggattag aaatctgcaa accataatgg agtcgaaaat aagttgaaga taaatgagac
     7501 cttaaatttt gttttagtag ctgatcttct tttaatgaat agcctagaaa ctgttccact
     7561 tgttcgatca aatgatcagc aagtgcgcta gattcctttt gaaaacgtgt ggctgcttgt
     7621 gaatttgtaa aaagattggc gatacgcaaa gccagataat tgatttcatc aggagaaaat
     7681 tcaattggat agatggtggc tagttttgct aatatttgac tacttaactt ttgtgcttgg
     7741 gtgtgttcca cgacttcgtt ttcgtcttta cttaatttca ctttctggta ctgtttcatt
     7801 cgctcgagca taaagtagat gtgaatctcc acactagcca gtccattcgg ctgttctaaa
     7861 tggttttcat aaaaaacatc ttgtaatgta tgttggataa cttttaatgt atctttagcg
     7921 aagaattctt tcaacgacgg actttgtgga tcttctttct gcatatttcg taatgtctta
     7981 acaagcaact gtcttttttc ttgttcatcg cctttaagaa aagttcctag ttttgttttg
     8041 gatactagct gtaaatggtg atactcaaaa aagctttgca actctgtcaa ttctttacga
     8101 atcgtacgtt ttccaacata tagtttttct gaaagttctt caagactaaa tccgtctttt
     8161 gctactagca gatggaaaat caataactga cgaagctgtt ttttatccat ttctgtttga
     8221 gtctcttcat taagcgctcg tttcagttgt tccctttcgt gaggcagacc attcaacaag
     8281 atacctgtac ctttttttct ttcaaacatt aaaggcagat gtttgtctct caaccaagtt
     8341 tcaatggtat tcaaatcgct atgaatcgtt ctttctgaca catggaaatg ctctgctagc
     8401 ttttttgttg ttatataatt attgttctca cttaattgat agatcaaaga ttgctgacgc
     8461 tgattcataa tgtgcagaaa ctcccttcta aataaaaaat cgatcatgat aacacatcta
     8521 ttatgtctca tcacggtcga tttttcatct tatgttacat ttcgcttaat aattggtgaa
     8581 ctgttgtttt atctggcgct tccatcagtg cttgacggaa gtcatcatcc atcaatttac
     8641 gtgatagacg ttgcagtatt ttcaagtgca tatcaccttg gctgttttca ggtacagcaa
     8701 tcataaagat catatgtgca ggttttccat ctaaagaatg ccaatctacc ccagattgac
     8761 ttctggcaaa tgccactgtt ggtttaagaa cataagctga ttttccatgt ggaatagcaa
     8821 tccccatacc gattcccgtt gtactttcat gttctctatc atagatgact tctttaaatc
     8881 tggttttatc tgtgatcgcc gctgtttttt ctaaacgttg gactaaatct tcgattactc
     8941 cgtcttttgt tgttgctgtt tcacctaaaa cgattgcttc atctgacata atatccgtga
     9001 tagaatcaaa agtttcagtt ttcgtataaa catcacttgt ttcagtctct gatagatctg
     9061 ctactgtcac accatttgct gcagcaaccg cagtttgttg taatgtcggt ttaaggattc
     9121 ttaacattag cacggttaca gcaataccag caatcactgc tacaaaaaac atggctacgt
     9181 gatccactgc tcctaaaacc gctacgatcg gaccgccatg agctacatga tctgtcactc
     9241 ctgaaagcat cgcgatcaca cttcctgtca ttgccccgat tacaatgctt ggaatcaccc
     9301 gtagtggatc tgttgaagca aacggaatag cgccttctgt aatcccaaac agtcccattg
     9361 ctaaggacgc cttaccagct tctcgttctg ttttcgtaaa tttggttttt aaaatcaatg
     9421 atgccagccc caatgctaat ggagggatac agatagctac agcaattggc cccataatgg
     9481 aataattgcc ttctgcaatc aagccagatc cgaacaaaaa ggctacttta ttgaacggcc
     9541 cccccatatc aaaagcaatc atcgctccta agatcatagc tagaacaatt tcacttcctc
     9601 cttgcatccc tgctaaaaag tgagtcaatg aactaaatag aagagctact ggttctccaa
     9661 taacatagat aaacacaaaa ccaactgcca atgatcctaa aattgggata acaataattg
     9721 gcatgatcga ttgtaaagct ttcggtactc gcactttctt gattcctaaa gcaatgaatc
     9781 ctgctaaaaa tccagtgatg atcccgccta agaatcccgc attcgcatca ctaccatata
     9841 atgctccgtt tgccgctaac atcccaccaa caaatccagg aacaagtcct ggacgatctg
     9901 caatactttg cgcaataaat gcagatagaa ttggaaccat caaccccata gcgatacttc
     9961 cgatactatt catcgttgcc caaatcgttc cttctggtat cttgatccct tcaggtgtag
    10021 ctgttcctcc taatgttaaa gaaatcgcga tcaataaccc tcctgtaact acgaaaggta
    10081 ccatgtacga aacgccattc atcaaactct tatagatttt tttacctaaa ttttctgatt
    10141 cacttttatt ttcggaagaa ataattgcct ccgtactttt atagactggc gcttttcctg
    10201 ctaaaatatc tctcaccaac tcatctgcat ggtggattcc ttcttgcaca cctacggtta
    10261 tcaaaggttt accgccgaat cgtgatttat ctattttagt atctgctgcg atgattacac
    10321 cagctgcttc ttcgatatct cttgcagtca attcattttc aataccgatg gaaccatgtg
    10381 tttcgacttt tacctcggcg ccaactgctt tccccgcttt ctctaagttt tctgctgcca
    10441 tgtatgtatg ggcaatacca actggacagg atgtgattgc aataattttt ttcattttcc
    10501 taccgccttt ctacatttat agtatataaa aacggtttct ttttattaag cacaaaatga
    10561 ttccgtaata actgaaattc ttggaataaa tagaaatttc gctaaaaaaa ttgatatacg
    10621 atttattatg ttgaataaaa taatattgga aaatcttaca tttctgtact tctgcttacg
    10681 tacatctaaa ttattatcta cattaacaat ttccgtaatt aattataaaa agcttattcc
    10741 atttaatttc attctggaat aagcttctta ttttctaatg agttagtgaa taattttttt
    10801 taccatgctt aatagtatct ttacgtctcc tatacgcgta tctcctgttt ctttatctat
    10861 aattgaacta taaacatgag gaatcacttt ttttacacct gcatcgattg caattttcag
    10921 aatttcttca aagtttgaaa gatcaattcc tcctgttggc tctaaataga attcatattt
    10981 tgcgcaagct tccgcaactg ctttaaattc ttccctatgt gctaagcctt tcatcgggaa
    11041 atacttgatt gaagtacctc ccatgtcttg cagcatttga atggcagttt caataggcac
    11101 ttcagctgct ggcgcttgtg aacttaacgg acctgtagca atattgacat agccgatctt
    11161 acctgttggt gaaaccaatc cattgatgac tgtatcattt tggcccaata aagcacgaga
    11221 agtccccacg ccagtaaata cttgattgac atgttgtggt tgtaaaaccc cagataaacg
    11281 cgaaaccatc tgactttggt ttggatctcc agcgcctaat ccaactgaca acgcattatt
    11341 ggttgcgtct tggtaccttt tcatatcttc gattgctgct tcatcgctag cataattttt
    11401 cgatagcaca cctagtacga catgcccttc cgctgcttca tagcatgctt ttgcattttc
    11461 aactgaatga gctaatacat ttaaacatac acgattttta taataatttg ggataactga
    11521 caatttaaaa gcctcctaca tgatttctct caatcttttt ataatttttt ccatttcgtt
    11581 ttggctgacg gaacgaatgt cgaactcaat gattccgtta tttgcttgat attctcgggt
    11641 gtagactgct ggatttcgtg cttttaattc ctgaatgact tctttcgcac ttttatcgcc
    11701 attaatcgtt acacttgctc gataaatatc tctgccggca ccatcttgaa ctattttcgc
    11761 tgaaaggtca ggaagttgat tgattgcgtt aacaaaaggc gctaatcgtt gcttcatgga
    11821 gtcaccggat tcgctcccat tttttaaata atcttctagt gcctgggtaa agcctaaaat
    11881 attatcttta ccgattttca ttgctcggcc aataccttta gactgtagcc gaatccattg
    11941 aatatacttc ttttttccta tgaccagtcc ggcactcgga ccttcgattg cttttgcccc
    12001 agagtaaatc actaagtcaa cgcccatttc gctatatttg aataaatctt cttccgcagc
    12061 tgcatcaacg atcaatggca aacgatgagc tttggcaact tctaccattt ctgccaccgt
    12121 cagcatactt ttctgaactg catgatgact tttaatatat agaagcgcag cagttttttc
    12181 cgtaatcatc atggaaacat gttccggtgt acacatattt gcatagccag cttctatgac
    12241 ttttcctcca ccttgagcaa ccattacttc aaccggtgtc ccataatcta cattatgtcc
    12301 cttaggtatg atgatttccc gtctagcgat tttttctgta tagggatgat agacatggta
    12361 catgtcgccc tgtccgatta aagcagcaac agattgagca atccctgctg aagcagaaga
    12421 aacgatttgc gcatcttcca ctttcagtaa ttgagaaaga taagcgccgg ttttgatggc
    12481 aagatcactc atctcaaaaa aatgctcgcc tccaaatcgt tgtgctgcta ggacactttc
    12541 agatacctta gaaaccccta ggatcgtcat ttttcccgat gcattaatga cttcttttaa
    12601 atcaaacttt ccatagctaa ttgtcatata tgacgcctcc aataattgtt ttaatcggta
    12661 aaatttgttc tttagctata cgtgtaaatc cgttggaatc tttcaattcc ttttcatttt
    12721 caacaatctc aaatatcgtc aaatctgcat cataattgac agctaactgg cccttattct
    12781 tcaaatgaaa attccgtgca ggaactgctg taactttttc aatgatttct tcccaagaat
    12841 agccgactac cctcaatttt tctaaagtag ttgctagatc aaaaactggg ccatttgtac
    12901 gattgcggat gtagatatcc gtactaatag aggtagcttt cattcctgct tttagtgcgg
    12961 tttctgccac atggaaatta aagctatccg tcccatgtcc aatatcaaag acgacaccat
    13021 tattgtaagc atcccagaca aagtttttaa tttgatctgt ctttggatct aaaataccgt
    13081 ttggttttcc attaaaacaa tgggtcaata catcgcctct ttccattctt gacaatactt
    13141 cttctaactc aggaggtgca gaaccgatat gaaccatcaa tggcagatca ttgttttctg
    13201 tctggatttt tttagctaat tctaatggct taatgccatt ttcaccaaca actgtcttac
    13261 tcattctcgc tttaatcccg acaataaatt ccggcagttc tgctaacgca gtacttacta
    13321 gatcttcttg aatctttgtt agatcagcaa gttcatcttg tttgacaatg ccccatttag
    13381 agatattcat tagcgcatac acatttgtct tgaccgattt cgtcaattga taaaattcac
    13441 ggatgttttc tgctcccgta gttccagcat caatgaccgt cgtcacacct ttttcgaccc
    13501 ctatctgatc aggatagtca taataaagat tcatcttttc atagcagtgg acatgatcat
    13561 cgatccaccc agcggataaa taatactttc cctccaagtc aactacttct tgcgccggct
    13621 gatttatttc tgctgcaact gctttaatca tgcctttttc tatagcgacc tctattttag
    13681 atccatcaac taaccttcca tttttaatca aagtatcaaa catttaatga ccctctttct
    13741 attaatttac tgccgggaag attgctccta aaatagcacc tccagcaatt ggttttttcc
    13801 aagcatagaa tcctagtgct cctaatgtag cgccaatgcc gattggaata gatgctgcac
    13861 acgcgcttaa tataattaat ggacccaaaa aacgtccaga tgaatttcct gcccccatca
    13921 tgacgtcagc accaaaagtg gaatttgatt gattgatcgt aaatttacga atcaagacaa
    13981 tgatgccacc aacaatcaaa cctagaacca aaccagtcaa taaagagagt gcaaaattat
    14041 cgattggtgc cgctattttc atacttaaga gaattgctgg taccccaatt ccgatcccag
    14101 ttaggatcga accgcctaag tccaagatcc caactaaaga gccttctaaa attctggcaa
    14161 ataagaaact agcaccaaac gctgccgctg cgccatagga tccgccatcc agcccggctt
    14221 ttaacatcgc cacgatcgaa acttcattga atgcacccac accatacatc acatacatgt
    14281 gtgttcctgc aaatacagca gcggacataa ttcctacgat tagcggaaaa gaccagtctg
    14341 caaaccaaaa gctcttttgc cgctttgctt ctaatacttt tgcttgttct tctgttgtct
    14401 ccatgattct cctcctattt cacactaaag atgttgtgca agttatcaag ccaattaggc
    14461 acttgaagct ggaagctctt gatcatttcc atatcaaatc cacggaaaaa tccactgaaa
    14521 ataaataata aaacaatagc gatcatcatg ctcttcgtga cgcgattcca accgctctca
    14581 tcgacgcctt taccaatcaa gattcctaga acaacaccag gtaccgcatt tcccataatc
    14641 aattgcgcga taccaccaaa aagagtgccc caaaaaccag ttcgtttccc tgcgtctaaa
    14701 gctgccaacc aaaaaataac tggcattact gtattgatca gaatcgtcgc tgctggtacc
    14761 aaaacggaaa ccgccgtcac ttgtaacgcc tctggaattg ctgcagctgt tgtgtttaag
    14821 aaggctacca ccactgcccc gataaccgct ccaatgatcc ccattttttt cggatcatgc
    14881 atggtctggg tgacatcttt gttttttgct agaagtgctg ccgctgccca attgggaatg
    14941 attcgatgcg tcacatcttg tgtgaatgca ccagcaccaa ctgaagaagc ccatgcatta
    15001 aagaaaaagc ctaaaccaaa tgaaaaatga gaagctggat cacccatgca ggcattcatt
    15061 tcgcctaatg ttctaaaagc tcctaaacct tgtgtattag gtgcatgaaa cattcgagct
    15121 gccccgacag atgctgcaaa accaagtaat cccccgataa tgaccgattt gactagaatg
    15181 attacgaaat ccacgttatt ctttccccct tatgattcaa aattagattt ttttagttac
    15241 aaatggaatg gcaatcccat ttggatcttc agtcatttgc tggctgaacg atatgtctgc
    15301 caattttatt tctgttacag ccacagtaac agagagttcg acttcatagc taatacgttg
    15361 ccgtgggaag aagaaaaata gaaagcgttc tgtgtatttg ttttcgaccg cctttaaaat
    15421 atccacattg actggttcga ttcgcaataa tacgtttgat tgttccatta ttttgttttg
    15481 aatttctgct aacgctgatg caaaagcatg ttgctttgtt tcccctttac cggagacgat
    15541 aactttttgc tgaattgtct tttgaacgct catttcatgt ccctctttct attttccatg
    15601 ctttttgata aattcttctg tcagacgttt ccctaattcc tcttgatcca taaagccgaa
    15661 acctagaaca gttttgccat ccttgatagc tgtgatccct tcttcaatcg aacgcatacc
    15721 atgtcgttct ggatagccat attttgttgc tgctgttaat gcacctgcac caccactacc
    15781 acaaaaagag atacccatat ctgcatgctc ttgttgcatc acatcgccca aacgcatatc
    15841 tgcccccatt cctggtacga caactgcttt tccaccagct gcttctaccc ctttggccac
    15901 attttgtcct ttacccatac ggtctgcaat aactacttta atcatgattg
//
LOCUS       DBBGSP010000064        15931 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000064 DBBGSP010000000
VERSION     DBBGSP010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.064"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            133..3660
                     /locus_tag="ACIZE9_002458"
     CDS             133..3660
                     /locus_tag="ACIZE9_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HGC6094277.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="ACIZE9_002459"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="ACIZE9_002459"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGC6094278.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="ACIZE9_002460"
     CDS             7448..7789
                     /locus_tag="ACIZE9_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HGC6094279.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="ACIZE9_002461"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="ACIZE9_002461"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGC6094280.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /gene="pheT"
                     /locus_tag="ACIZE9_002462"
     CDS             9146..11566
                     /gene="pheT"
                     /locus_tag="ACIZE9_002462"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGC6094281.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACIZE9_002463"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACIZE9_002463"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGC6094282.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="ACIZE9_002464"
     CDS             13000..13737
                     /locus_tag="ACIZE9_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGC6094283.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="ACIZE9_002465"
     CDS             13751..14566
                     /locus_tag="ACIZE9_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGC6094284.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="ACIZE9_002466"
     CDS             14579..15226
                     /locus_tag="ACIZE9_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGC6094285.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="ACIZE9_002467"
     CDS             15242..15898
                     /locus_tag="ACIZE9_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGC6094286.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
BASE COUNT         5340 a         2745 c         3377 g         4469 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta a
//
LOCUS       DBBGSP010000065        15860 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000065 DBBGSP010000000
VERSION     DBBGSP010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.065"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(12..482)
                     /locus_tag="ACIZE9_002468"
     CDS             complement(12..482)
                     /locus_tag="ACIZE9_002468"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGC6094287.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="ACIZE9_002469"
     CDS             complement(641..1099)
                     /locus_tag="ACIZE9_002469"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGC6094288.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="ACIZE9_002470"
     CDS             complement(1270..2415)
                     /locus_tag="ACIZE9_002470"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGC6094289.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="ACIZE9_002471"
     CDS             complement(2428..3345)
                     /locus_tag="ACIZE9_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HGC6094290.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="ACIZE9_002472"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="ACIZE9_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGC6094291.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4437..4607
                     /locus_tag="ACIZE9_002473"
     CDS             4437..4607
                     /locus_tag="ACIZE9_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094292.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            4822..6081
                     /gene="lysA"
                     /locus_tag="ACIZE9_002474"
     CDS             4822..6081
                     /gene="lysA"
                     /locus_tag="ACIZE9_002474"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGC6094293.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6068..6868
                     /gene="dapF"
                     /locus_tag="ACIZE9_002475"
     CDS             6068..6868
                     /gene="dapF"
                     /locus_tag="ACIZE9_002475"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HGC6094294.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6871..7752
                     /gene="dapA"
                     /locus_tag="ACIZE9_002476"
     CDS             6871..7752
                     /gene="dapA"
                     /locus_tag="ACIZE9_002476"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGC6094295.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7749..8465
                     /gene="dapB"
                     /locus_tag="ACIZE9_002477"
     CDS             7749..8465
                     /gene="dapB"
                     /locus_tag="ACIZE9_002477"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGC6094296.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8471..9166
                     /gene="dapD"
                     /locus_tag="ACIZE9_002478"
     CDS             8471..9166
                     /gene="dapD"
                     /locus_tag="ACIZE9_002478"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGC6094297.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9182..10183
                     /locus_tag="ACIZE9_002479"
     CDS             9182..10183
                     /locus_tag="ACIZE9_002479"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGC6094298.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10180..11541
                     /locus_tag="ACIZE9_002480"
     CDS             10180..11541
                     /locus_tag="ACIZE9_002480"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGC6094299.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11501..12652
                     /locus_tag="ACIZE9_002481"
     CDS             11501..12652
                     /locus_tag="ACIZE9_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGC6094300.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12627..13796
                     /locus_tag="ACIZE9_002482"
     CDS             12627..13796
                     /locus_tag="ACIZE9_002482"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGC6094301.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            13971..15350
                     /locus_tag="ACIZE9_002483"
     CDS             13971..15350
                     /locus_tag="ACIZE9_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC6094302.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15631..15860
                     /locus_tag="ACIZE9_002484"
                     /pseudo
     CDS             15631..15860
                     /locus_tag="ACIZE9_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5185 a         2799 c         3378 g         4498 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtca ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcttctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcaga
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat cgggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaaaa tattttttca tcactaaata gtgttgaatt
     4621 tatgttttta tgtataaata gcttctaata gttcgggtat tttgttttta taaccatttt
     4681 tattcttatt tttaaaaaaa tatttcgaaa tatactagac aattcagaaa attttgttta
     4741 atattattcc aataaaattc aaatctttat caaatgaaat tccaataaaa acggaaaaaa
     4801 agtgaaaaga ggaatgaaaa aatgacagaa ttgataattg gcggagtcac agcaagcaca
     4861 ttggcagaaa agtataagac acctctgtat gtgtatgatg aagaaaagat gagacaaacg
     4921 atgctgtcat tcaagcgagg ctttgtatcg aaacgttttg atacaaaagt gctttacgcc
     4981 tctaaagcat tccaaacgat tgagatgctg catttagttc gtgaatatgg attcgggcta
     5041 gatgttgtca gtggtgggga aatctatacc gctttgcaag ctgattttcc tagagatact
     5101 atctacttcc atggtaacaa caagacgcca gaggaactga tctatgcact tgaaaatgat
     5161 ttgttgcata ttgttgccga taatttgatg gaagttgaat tattagcaga attaagccaa
     5221 cgctatttaa aaaaaatctg tatcatgctt cggttgaatg tcggagtaga agcacatact
     5281 catgaatata tcgtcactgc gcatattgat tcaaaattcg gcatgagcta tgaaagtaaa
     5341 gagtgccaac aagcccttca gttgataaaa gaaagcagct atctagagtt agaaggattt
     5401 catgctcata tcgggtcaca aatttttgat gttactgctt ggttagctga aatcgacaaa
     5461 ttgacgaatt acttaaccga ttttgaccaa cctctttcct tgaatcttgg cggagggttt
     5521 gggattcgtt atacacaaaa tgatcagccg atcccagtcg aagaggcact aaaaaaactg
     5581 attgaatata cggaagaagc tttggaaaaa cgaaaactga ccattcgtca attactgatc
     5641 gaaccgggta gaagtattgt tggagaagct ggtacaacac tatacacgat tggtttcatc
     5701 aaaaagacac cacataaaaa atattacttt gtagatggcg ggatgacaga taatatccgt
     5761 ccagctctgt atcaggcaga atacgattgt gatttagcag caaaactgtc ggaagaaaaa
     5821 acagagaaag tgacgattgc aggaaaaatg tgtgaatcag gcgatgtggt aattaaagaa
     5881 gcttatttgc cgaaagcaga atcgggtgat cttttagctg tttattccac gggagcttat
     5941 ggatactcga tgagcagcaa ctacaatcga gcgacacgac cagcagttgt ttttgtcaat
     6001 aatggccaat caagactgat tgttcgcaga caagcatttt ctgatctact aaggggggaa
     6061 gtttcctatg atccttcata aatataatgg ctgcggaaat gattttatct tattagatta
     6121 cgcagaagac acagattata gtcaattagc cgcttcttta tgcacaaaag aaaaatatga
     6181 tatagacgga ttgatcgccg taaaaatcga tccgttggaa atgatctatt acaacaaaga
     6241 tggcagccgc gcgccgatgt gcggaaatgg cattcgctgt tttgctcgat acgtaaatga
     6301 tcagaacatg atgaatgaac aggaattcaa cgtagagaca ttagcaggca caagaaaaat
     6361 tacggtgttg gatccctcac ctttttattg cagcgtagat atgggagtgc cagatgattc
     6421 tccggaaaaa atcaaagcta atcaaactta tccaataaaa aaccaggaaa tagagatcaa
     6481 tggtgaaaaa gtaacgatca ctagtttatt tttaggaacg attcataccg ttgtttttgt
     6541 tgaaaatgcg cgtgaggaag tctggagaaa aagaggtgaa ctgatctgtc atcatccttt
     6601 gttcaaagaa aaaaccaatg tcaactttgt agaagtagtc aatgaacaag aattgatcgt
     6661 ccgtacctat gaaagaggag taggttggac acttgcttgc ggtacaggtt gctgtgcctc
     6721 ttatgtggtt gctaaggaaa ctgggaaaat ttcagcagat caggtagttg ttcacttgga
     6781 acaaggagac ttgatgatct ctggtgagga tgcgatacaa atggctggcc cagcagttca
     6841 tgaatggaca agaatattgg aggaatgaag atgataaaag gttcgatcgt ggcgctgatc
     6901 acgccgatga atgaagaggg atcagtagat tatgctggtt tggaaaaatt gatccaattc
     6961 catttagatg aacaaacaga tggattatta gttttaggta caacaggaga atcttctacg
     7021 ctcacacaat ctgaggagga gcagatcctt caactgacag taaagaaagt ggctggccgt
     7081 gtgccggtga ttgcaggagc tggaacgaat aatacgaaag aaacgattga aaaagcgaag
     7141 cattttgctt ctttgggggc agacgcactt ttggtcatca ccccttacta caacaaaaca
     7201 agtgatgcag gactagctgc tcattttaca gcaattgcag aagcctcacc gattccgctt
     7261 attttgtata atgttccttc tagaacaggc atgtcgattc caatccatgt attagtaaat
     7321 ttagcagaac atcctaatat cattggtttg aaagaagcct caggagatat ggcttatgtg
     7381 atggatgccg ctcggttgat tggagaagaa ttcttccttt acagtggaaa tgatgatttg
     7441 atcctaccag taatgagtgt aggaggaagc ggtgtaataa gtgtatgggc gaatatccaa
     7501 cctaaaatag tccatgaatt agtaaaagat acgcaggacg gaagatggca gcaagcaaaa
     7561 gaaaagcaat taaatgcact tgaactgatc catgccttgt tcagtgagac caatcctatt
     7621 cctgtcaaag cagccatgtc attattagac ttaccttccg gacctctacg cctgccttta
     7681 gtttctcttt caaaagagaa aaagaaacaa ttagctcagc ttttgttaaa agaaaggacg
     7741 gttgaaaaat gaaaatcgga ctgattggca gtggacagat gggaaataga gtcgaagaag
     7801 ttgcacaaga aagaggagat acggtccttc ttttacggac ggcacctaaa gaagcaacta
     7861 cgcttgcttt tacggaactg ccagaactgc ttattgattt ttctcatcca gataatttag
     7921 agaaaatcct ttcgtatagc ttatcatatc aacttccgtt agtcattggc acgacaggtt
     7981 atacacaatc acagttccaa gaaataaaag aacatgccaa acatgtacct gtgatgtata
     8041 gtgctaattt ttcgttcggc atcatggtga tgaatcaact aatcaagcaa gcagctgcaa
     8101 tgttgcaagg ctggcagatc gaactgattg aaaaacatca tagtcgtaaa aaagatgcac
     8161 catctggtac tgcaaatatg ctgcttcaaa caatccaaga agtgcaaaag ctgcagcccg
     8221 tatacaactg gcaagggaaa aaaagagaag aaaaccaaat tggtgtacac agtattcgtg
     8281 caggttcttt acctggtgaa catgatgtat tgtttgctgc tactgatgaa atatttacga
     8341 tcaaacatga atctttttct aatcgaatct ttgctgcagg cgcagtagaa gcagcggact
     8401 ggttgaaaga tcagtcacca ggttattaca aattagaaga tttattaatg gacaaagggg
     8461 tgtaaaaaac gtggaagctc aagaaatcat ccgctacatt caaacggcat ctaaaaagac
     8521 gcctgtgaaa gtctatctga atgtaaccga gccaatcgaa tttaaagaaa gtaaagtttt
     8581 tggtgaagga agcagcttcg ttgtttttgg tgactatgag acgattgctc cggttttaga
     8641 agctgaatca gaaaaaatca ttgaaatcga aatcgaaact gctgcaagat acagcgcagt
     8701 tcctttgcta gatattaaaa aaattaatgc tcgtatcgaa ccaggtgcta ttatcagaga
     8761 tcaagtgtca atcggcaaca atgccgtgat catgatggga gcgattatca atattggtgc
     8821 agtaatcggt gaaaacacga tgattgatat gggtgctgtc ttaggtggac gagcgacagt
     8881 gggcaaaaac tgccatattg gtgcaggagc tgtcttagca ggtgtgatcg aaccagcatc
     8941 ggccaaaccg gttatcgtag aagacggcgt actggtaggt gcgaatgcag tgattgttga
     9001 aggtgtccat atcggaaaag atgcagtcgt ggcagcagga gcagtggttt tagaagatgt
     9061 ggcagcagaa actgttgtcg gtggaatacc tgcacgtgta ttaaaaataa gtgatgatca
     9121 gacaaaagaa aatacagcat tgattgctgc gttacgcgaa ttatagagga gatggagaaa
     9181 aatgcgcgaa atagatacct gtattgtggg ggcaaccgga ttagtcggcc aaacgatgct
     9241 caaagtgtta gaagaatatg attttccagt aggacgattg aaattattag cttcaaaacg
     9301 ttcagccggt aaagtttgtg tattcaagaa aaagaaacac actgtacagg aattgacaga
     9361 aacttcattt gaaggatatg atttagcgct attttctgca ggtgcttctg tatccaaaga
     9421 gtttgcgcca atcgcacgaa gtcagggact atttgtcata gataattcct cagcatggcg
     9481 ggaagattcg gatattccat taatcgttcc agaggtcaat ctggaagact atacattgaa
     9541 tcggctgatt gcaaatccaa attgttcaac cattcaagcg gtacttccgc ttaaagcttt
     9601 acaagaagcc tttggtatcc agcgagtcaa ttattcgacc tatcaagcag tttctggttc
     9661 cgggcaaaaa ggcattgaag atcttcatcg tacgcaaaat gacgaggaac cagttttgta
     9721 tccttataat attagccaaa cggtgattcc ggaaatcgat cagcctttgg aaaatgggta
     9781 tacaaaagaa gaacagaaaa tgataaatga gacccgtaag attctgcatc agcctgcttt
     9841 gccagtatca gcaacctgcg tacgtgtgcc aatcgaaaat ggacatggag tctctgtggc
     9901 agttcaactg caaaaagagt ttacgacgga agaaattaga gagtgtctca gccagtttcc
     9961 agggattcaa ttagaagatg atctagcagc acataaatat ccgacgagca ttcttgctag
    10021 aggaacagat atggtttatg ttgggaggat cagaaaagac acttctttag agaacggatt
    10081 gttgttctat acgactgccg ataacatacg caaaggagcc gctgcgaatg ccgtacagat
    10141 tgctgcagct ttaatgcaga aaatagcgga ggtggcaaga tgagtaatac gctgaaagta
    10201 gcgaaattcg gcggaacatc gatgtctcat gaagagcaat tcaaaaaagt ccgtacaatt
    10261 gttctttcag atcccaatcg ccaagtgatc gttgtttctg ctttaggcaa acgtacgtca
    10321 gatgatgaca aagtaacaga cttactttat ttgatttatg cttaccttca gcatcatgtt
    10381 gattggacac ccctttggaa aaggatttgt gatcgtttca ttcaagtaag agatgttctt
    10441 gccctgcagt tacctattga agatgaacta gcacgcatac agaaacaact ggaagacgaa
    10501 aagataactg aagattattt agtaagtaga ggtgaatatc tgactgctca actgatggct
    10561 gagtatcttg gttaccagtt tattgacgca aaagacctga ttttctttga ctatgatggg
    10621 aaaatcgatc aggaaaaaac agcacaggaa atcacaaaag catttaaaag atatccgaaa
    10681 atggttgttc cagggtttta cggggcgaac cctgcaggaa aagaaaaatt attgggccgt
    10741 gggggaagcg acattaccgg cgcgatactg gcgaagatgt tgcaagcgga aagttatgag
    10801 aattggacgg atgtttcagg aatcatgatg gctgatccgc gaatcatcga tcatcctaaa
    10861 atcatcgagg aaatctcttt tagagaactg agagagatgg cttatatggg ggctaacgtt
    10921 cttcatgaag cagctgtttt cccagttcaa gaggctgata tccccatcca aataaaaaat
    10981 accaatgatc ctttcgctca agggacaaaa atatcgaatc acgaaataga aaaggaaaat
    11041 ggactgacag gaatagctgg acgcaaggat tttctttcca tcactttatt caaacgtcat
    11101 atgtccgatg aaatcgggtt tatctggaaa gcaatgagca tttttgctaa acatgagata
    11161 tcaatcgaac atattccttc agggatcgac aatatcggag tgatcgtctc agcagaagcg
    11221 attgccgata agttatttct catcacgaaa gaattaaaag aaacacttgg cgtggaagaa
    11281 atcgtcgtga tcgaagactt agctttgatc tctgtcgttg ggggtccgca taaagaattg
    11341 attggattat ctgggaaagt gttatcgata ttgaacaaat tagaaattcg cacatcgatc
    11401 ttatcacaag gagcacagga gttgaatctg atcatcggtg taccgaataa tcaatatgaa
    11461 acagtagtga agggtatcta tgaagggatg gtgaatacgg atgctgaaag aatatcgaat
    11521 ggcactccat caaattcctg aaatcgggtt tcatgaattc aagacaaaaa aatatttata
    11581 tgaacaagta aaaaacagcg aggccgttat ccatgaaatc ggcgaaacag gactactcct
    11641 ttattttgat aatcagcaag aagaaacgat tgcttttcga acagatatcg atgcactgcc
    11701 agtcaaagaa gaaacgaatc tctcttttgc ttctaagcat gaaggttata tgcatgcatg
    11761 tggtcatgac ggacatatgg cgatgctttt agggttgact gactttataa ctaaacacat
    11821 tgaggatctt atttataatg tagtactgat ctatcagcca tcagaagaaa tttccggtgg
    11881 cgcacaaagc gttattcagt caggattgtt ggataaatat gaagtacaag caatatttgg
    11941 ctttcatcta tggcctggac tagctaaggg agaagttttc tctcgaccag gacctttgat
    12001 ggcacaaagc agtgaaacag acattatcat taaaggccag tctgcacata ttgcttctag
    12061 tgaaaaagga atcgatagtc tggaggcagc tgtacgattt ttgaagaatg tttatgattt
    12121 tgaccggcaa ttaccggcag agtggaatca tctaatgaaa tttggccaaa tccaaggtgg
    12181 aacgatccga aatgttttag ctggagaagt tattgtatcc ggaagtatcc gttcttacag
    12241 ttcagatatg caaaattatt tgaagagggg attagaccat ttagcagaac agtttcactc
    12301 tacagctact atttcttttc gctataatga cggctatcca gctgtaatca accatagagg
    12361 cttatatgca gcactgttag attcaaacaa actacatgaa ttagatgctc cagttcttca
    12421 agccgaagat tttggcatat atacgcaaca atatccatgt gtatttttct ttttaggtgt
    12481 cggtgatacc cctgctttac atgatccgac gttcgatttt gatatggatg ttttagaaaa
    12541 tggtgtagaa tggtacaaaa cgattctttt tacagaaaat cttcttgtaa aaatcgatag
    12601 cagttcaaaa gaggagcgag taaataatga tgaatttatc caatcgattt agtcctaggc
    12661 tttctagaat agaagtatca aaaatacgac aattcgatca gcaaatatcg tcgataccag
    12721 atgtgatcaa actcaccctg ggagaaccgg attttccaac tcctgaacat gtcaagcaag
    12781 caggaatagc agcgattgaa gaagactttt ctcactatac cggaatgaga ggattagagg
    12841 aactgcggga agcggcttgt atatttcagc aacagcgtta tggattaact tatgatccgc
    12901 aaacggaagt tttgacgaca gttggtgcaa cggaagcgat tgcctctgcg ttgttatctg
    12961 ttttggaaga aggagacaag gttcttattc cagcgcctgc ttattcagga tatcagccat
    13021 tagtggaact agctggtgct gaattgatcc cgatagatac ttctgacaca gggtttgtct
    13081 gtcagccgga acaatttgaa cgagcatttg aacaatatgg atcagctgtc aaagcagtca
    13141 ttttaaacta tcctaacaat cctactggga cgacattgtc tgcaaaacaa ttgaaagcaa
    13201 tcgctgaggt tttaaaaaaa tatccggtat ttgttataag tgatgaagta tatgctgaat
    13261 tgacttatag tggaacgcat atgtccatag ctacttatct tccagaacaa acaatcgtga
    13321 taagcgggtt atccaagtca catgcgatga ctggttggcg agtgggcttt atttttgctc
    13381 aaaaagccct tattgacgaa ctaattaaag tccatcaata tctggtgact gccgctacaa
    13441 cgatgtcgca aaaagctgcg gctgaagcgc taataaatgg ggtgaaagat agcgagaata
    13501 tgaaagagca atatcaaaca cgaagagact atctggtcca gcaattggcg cctttaggat
    13561 ttgaagtgac ccagccaaac ggtgcatttt acttgttttg caaactccca gctgccattc
    13621 aaactgactc ttggcagttt tgtgtagaat tagcggaaca ggcaaaagtt gcgtgtatcc
    13681 caggaattgc atttggccca gaaggagaag gttatatccg gatttcttat gctagcagca
    13741 tggaaaaatt acatgaggcc tgcaaacgga tcaaagactt tttaacagaa cagtgattca
    13801 tagattttat caaaaaaaca atcgttaatt ttgcggtata ttctgcaagg agacgattgt
    13861 tttttaaatt tagttcaaat gaacgcgttt cttttgattc ataactaatg taatgttaag
    13921 tttaaattgt ttagaatgat tttaaaagaa tattcaagga ggtttcatca atggaaaaaa
    13981 tcaaagttgt cattgtaggt gcatctcatg gagggcatca atcgatcttg gaactattga
    14041 cacgatacgg tgaaaatgta gatatcacgc tatttgaagc aggagactat atttccttca
    14101 tgtcatgtgg tatggagctg tatttagaag acaaggtaac agatgtaaat gatgtacgta
    14161 atttcagacc agaaaacttt ccgcaatcca atgttcatat tttaaataat cacgaagtaa
    14221 aaacgatcga tgccgataaa aaaacagtaa cggttactag cgcatcagat aacgaaacaa
    14281 aagaatatcc ttatgacaaa ttgattttga gttctggtgt caaaccaaac aatctgccag
    14341 taccaggagc agatctagaa aatgtctact tgatgcgtgg atacaattgg gcaaccaaaa
    14401 tcaaagaaaa attaaatgat ccggctatta aaaaaatcgc tgtcgtaggt gcgggttaca
    14461 ttgggatcga agcagcagaa gcaagccgaa aagctgggaa agaagtcgta ttgcttgatg
    14521 tgatcgatag acctttaggc acttatttag atgctgagat gacagatatt ttagaacaac
    14581 acctaaatga aaacggtatt gaagttttga caaatgcaaa aatcgaagct tttactggta
    14641 acggaaaagt tgaggcaatc aaaacaagtg aaaaagaaat cccagcagat ctagtcattc
    14701 aagctgccgg tgtgaaggca aatacagaat ggttaaaagg gatcgtcgac ttagatgaac
    14761 gtggctggat ccaaacaaat gaatacttgc aaacgaatct tccagatgtg tatgcagtag
    14821 gagatgctac acttgcttat tctatcccag cacgcaaaaa aatgccgatc gctttagcga
    14881 ctgttgcacg tagagaagca cgttatgtag taaaacatct ttttgaagaa gtaccaaaca
    14941 aaccgttcgg cggagtcgta ggttcctctg cattaagtgt ctttgactat cattttgcag
    15001 caagcggatt gaatagcttt acagcagcaa aagcaggagt agatgtacga gtgtcttatt
    15061 atgaagatac gttacgacca aaatatgtac cagaagaaca aggaaatcca aaagtgtcca
    15121 tccaattatt ctcggatcca atgacccatc aattgctagg aggagcagta ttatctacct
    15181 atgatgttac aggtcaagga aatgtattgg cactagcgat ccaaaacaaa ctgactttag
    15241 aagaactagc agaagctgac ttcttcttcc agccaggctt tgaccgacaa tggagcatgt
    15301 tgaatctagc cgctcaacaa gcgttaggag aagaaccatt tgtagaataa gaaaacgaaa
    15361 tatttgaaaa gaggttgtga aaaagctgcc ttgcatcaag taataagaac agccaagtaa
    15421 aaacagcttc ttatgttttt aacttggctg gacttattac cgcagatgca agcttttgaa
    15481 caccgtttat tttcaaaaaa gggactgtga cacgatttgt gtaccgaccc ccaaaagtta
    15541 gaccaaaaaa tctaactttt ggaggtcggt attttttatg gttaaatata cttttgaact
    15601 taaattaaag atcgttcatg attatttgga tggcaaaggc gattggaccg taaaaatcca
    15661 gatcaagaga ttgaagcgga aatgcttaaa attcgggaga agcacaagga ttatggctgt
    15721 ttacggatga ccaatgaact aagaaaccgc ggtttctcta tcaataaaaa gaaagttcag
    15781 cgcttgatca agaagctagg aataaaagta acggcataca cgcgtaaatc acgtcgctac
    15841 aattcttatc gaggaaaagt
//
LOCUS       DBBGSP010000066        15230 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000066 DBBGSP010000000
VERSION     DBBGSP010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.066"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            278..787
                     /locus_tag="ACIZE9_002485"
     CDS             278..787
                     /locus_tag="ACIZE9_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC6094303.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="ACIZE9_002486"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="ACIZE9_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGC6094304.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="ACIZE9_002487"
     CDS             2322..3302
                     /locus_tag="ACIZE9_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6094305.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="ACIZE9_002488"
     CDS             3424..4842
                     /locus_tag="ACIZE9_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HGC6094306.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="ACIZE9_002489"
     CDS             4913..6382
                     /locus_tag="ACIZE9_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6094307.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="ACIZE9_002490"
     CDS             6392..6859
                     /locus_tag="ACIZE9_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HGC6094308.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /gene="scrK"
                     /locus_tag="ACIZE9_002491"
     CDS             6895..7767
                     /gene="scrK"
                     /locus_tag="ACIZE9_002491"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGC6094309.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="ACIZE9_002492"
     CDS             7848..10382
                     /locus_tag="ACIZE9_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC6094310.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10538..11311
                     /locus_tag="ACIZE9_002493"
     CDS             10538..11311
                     /locus_tag="ACIZE9_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGC6094311.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="ACIZE9_002494"
     CDS             11304..12095
                     /locus_tag="ACIZE9_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC6094312.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="ACIZE9_002495"
     CDS             12105..12596
                     /locus_tag="ACIZE9_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HGC6094313.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="ACIZE9_002496"
     CDS             12614..13024
                     /locus_tag="ACIZE9_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6094314.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="ACIZE9_002497"
     CDS             13028..14428
                     /locus_tag="ACIZE9_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HGC6094315.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="ACIZE9_002498"
     CDS             14451..14825
                     /locus_tag="ACIZE9_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC6094316.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5287 a         2134 c         3046 g         4763 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttaaatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcgatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 aatccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt
    15181 tttttatttt gaaaaatttt tagtattttt cgaaaaatgc tcactcctag
//
LOCUS       DBBGSP010000067        15120 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000067 DBBGSP010000000
VERSION     DBBGSP010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15120
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.067"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            5..2377
                     /locus_tag="ACIZE9_002499"
     CDS             5..2377
                     /locus_tag="ACIZE9_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HGC6094317.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..3898
                     /locus_tag="ACIZE9_002500"
     CDS             2438..3898
                     /locus_tag="ACIZE9_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HGC6094318.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3909..6113
                     /gene="topB"
                     /locus_tag="ACIZE9_002501"
     CDS             3909..6113
                     /gene="topB"
                     /locus_tag="ACIZE9_002501"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HGC6094319.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6129..6278
                     /locus_tag="ACIZE9_002502"
     CDS             6129..6278
                     /locus_tag="ACIZE9_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094320.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6353..6946
                     /locus_tag="ACIZE9_002503"
     CDS             6353..6946
                     /locus_tag="ACIZE9_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HGC6094321.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6959..7858
                     /locus_tag="ACIZE9_002504"
     CDS             6959..7858
                     /locus_tag="ACIZE9_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HGC6094322.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7861..8358
                     /gene="ssb"
                     /locus_tag="ACIZE9_002505"
     CDS             7861..8358
                     /gene="ssb"
                     /locus_tag="ACIZE9_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGC6094323.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8724..8984
                     /locus_tag="ACIZE9_002506"
     CDS             8724..8984
                     /locus_tag="ACIZE9_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094324.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9429..9635
                     /locus_tag="ACIZE9_002507"
     CDS             9429..9635
                     /locus_tag="ACIZE9_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HGC6094325.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9656..9886
                     /locus_tag="ACIZE9_002508"
     CDS             9656..9886
                     /locus_tag="ACIZE9_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094326.1"
                     /translation="MTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLVEDAPTML
                     FEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            9902..10339
                     /locus_tag="ACIZE9_002509"
     CDS             9902..10339
                     /locus_tag="ACIZE9_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094327.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10332..11039
                     /locus_tag="ACIZE9_002510"
     CDS             10332..11039
                     /locus_tag="ACIZE9_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094328.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11203..11403
                     /locus_tag="ACIZE9_002511"
     CDS             11203..11403
                     /locus_tag="ACIZE9_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094329.1"
                     /translation="MNKIIPLLFVLCIGEILMRHGAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKLIAAIFFIGLFR"
     gene            11419..11598
                     /locus_tag="ACIZE9_002512"
     CDS             11419..11598
                     /locus_tag="ACIZE9_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094330.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11923..12186
                     /locus_tag="ACIZE9_002513"
     CDS             11923..12186
                     /locus_tag="ACIZE9_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HGC6094331.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12180..12530
                     /locus_tag="ACIZE9_002514"
     CDS             12180..12530
                     /locus_tag="ACIZE9_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGC6094332.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12554..13168)
                     /locus_tag="ACIZE9_002515"
     CDS             complement(12554..13168)
                     /locus_tag="ACIZE9_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6094333.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13482..13904
                     /locus_tag="ACIZE9_002516"
     CDS             13482..13904
                     /locus_tag="ACIZE9_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094334.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            13914..14117
                     /locus_tag="ACIZE9_002517"
     CDS             13914..14117
                     /locus_tag="ACIZE9_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094335.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14328..14912
                     /locus_tag="ACIZE9_002518"
     CDS             14328..14912
                     /locus_tag="ACIZE9_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6094336.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         5562 a         2450 c         3060 g         4048 t
ORIGIN      
        1 gaacatggca gaagaaaaag aaccactaga caatagtcgt ttgggaaaat ccaaaagaaa
       61 actagtacga ttgcaaaatg aattaaacga acaaattgaa aagatgtttg aacaccaaaa
      121 aatgacgaac ggtcaaccaa tgaacgacaa gaggaatggc cgttcatggt ttaaccagca
      181 agaacgaatc gaaaataaag tccaaagtct gagagaagag atcaagcaac aagaagaata
      241 cgtggaaaag cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 actggatatg acgatcgata atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg gctttttcag ccgccacgat ccgaaaatac caacggaagt tggaaacatt
      421 agaacagctg aaagaaaaat cagaaaaagg aaaagaaaat atcctccctg aagtacaagc
      481 gatcattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 aggctatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctag
      661 accaactgat tctatgaagg agaaagaaaa cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tcgaattgat
      781 cgatcaactc aaaacattgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaggaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccaa tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 gaaggaacaa aaacaatcgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaaacaaga
     1081 agttaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 agacgtcaaa gaacttttga actttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ccgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaaggg ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actatacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca gttaaaacct gaagactatc cgaaaatctt
     1501 tccgaaccgt gtctttgatt ttcaattgga taaaaaagga cagtcagaac ttcaagctgg
     1561 gattcaagcg gtagccaaca atattggaat acaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgtgg ggcgtatgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cgtcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 tgcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctttagaaac gccagagaat aagaatattg tgcccgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtaa ttttaaaagg
     2221 aaaaagttat ggaaaagaga tccaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg agacagtgtc agaagtggca aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg tgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg ttttaaaatg accgagaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagatt atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ccctaagcaa caatttaaag cagccactga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtggaa aatcttcatt ttgaaacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gcagaaaaag aagggttgat
     2881 tgccgaacta aagccaaaat atgaacggca aaatttctta gttcgagacg atcgtttaga
     2941 tcatgcggtc gcctttttat ggaaagatcc acagacaaaa gagacagtag gggcgagtta
     3001 tcaaggaacg ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga
     3061 taaaaattcg acagcgaatc atggctttaa cctaaagatc ggtgacccta agcagataaa
     3121 attttttgag agtagtattg atttacttag ctatgctgca ctgaatcgtg atcagttaaa
     3181 cgatacgtgg ttagtctcta tggaagggtt aaaacaccat gtgatcagtc attattttgg
     3241 tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccatcg agatttgtgt
     3301 ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagtcga
     3361 tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc
     3421 aaaagaatac aaaatcattt atgaagaagt cgcaaaagaa gaaaaggtca caccagaagc
     3481 tattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaac tggtttccgc
     3541 tcacaaagta aatgcgtttt ttggccagca gctttctgtt aacgattcaa tagaagccat
     3601 taatttgaaa gatatttgta gagaagtcgc aaaagaatta aaagtttgtg aacgcgtgga
     3661 tggtacgtac gattttgatc gtttttatca agaaaaaggg gatattaatg cgcagattct
     3721 tttctcttat aaagcagaac aatactacaa aggctataaa aatcatgaac atgaatttgt
     3781 acctgaagta aaaaaggact ggaacgatca attgaagcat gagatccagc aacaagaaat
     3841 cagaaagcaa aaacgtgcca tgttgtttca acaaggcaga caacaagaaa gggagtgaaa
     3901 tcgtcatgat gaaaaccgtt attttagcag aaaagccgtc acaagcgaaa gcttatgccg
     3961 atagcttctc taaagccact cgaaaagacg ggtattttga aatccaagat cgattgtttc
     4021 ctggtgaaac tgtgatcacg tatggttttg gtcatttagt cgaattagat tcgcccgata
     4081 tgtacgatga aaattggaaa caatggtcat tagaacattt gcctattttc cctacacatt
     4141 atcactatca tgttcctaaa gataagaaaa agcaattcaa ggtggtgaaa cagcaacttc
     4201 aatcggccga caccattatt attgcgacag atagcgatcg tgaaggggaa ctgatcgctt
     4261 ggacgatcat tcaacaagta ggcgccgatc aaggaaaaac ctttaaaaga ctttggatca
     4321 actccttaga aaaagaagcc atttatcagg gattccagca gttacgagac gcaaaagaga
     4381 cctatccaaa atttgaagaa gcacaagcac gtcagatcgc cgattggtta attgggatga
     4441 acggtagccc actgtatagt ttactcttgc agcaaaaagg cataccagga agcttttcct
     4501 taggcagagt ccaaacccca acgctttaca tgatttatca attgcaggaa aagattagaa
     4561 atttcaagaa agaaccttat tttgaaggaa aatccgaagt aatcgctcaa aatggcgcat
     4621 ttgatgcgaa gcttgatccg aatgaaaccc aagcgacgca agaagcattt gaagattatt
     4681 taaaagaaaa gggggttcaa ttgggaaaac agccaggcat gattcgccaa gttgaaaccg
     4741 agaaaaaaag cgcggcaagt ccacgtcttt tttctctatc cagccttcag tctaaaatga
     4801 atcagctcat gaaagctagt gccaaagaca ctttggaagc catgcaaggc ttgtatgaag
     4861 ggaaatatct aagctatccg cgaacggata ccccttacat tacggaaggg gaatatgcgt
     4921 atctgttgga tcacttagac gaatacaagc attttttgag ggctgaagaa atttcgactc
     4981 ctattcatac accgaatagt aggtacgtga acaacaagaa agtccaggaa cattacgcaa
     5041 tcattcctac aaaaacagtt atgacagaag cgacgtatga aagtctgaca cctttacaac
     5101 aagcgattta cgagcaagtt ttaaaaacga cagtggcgat gtttgcggaa aaatatacct
     5161 atgaagaaac aacgatcttg acgcaagtcc agcagcttca gttaaaggca atcggaaaag
     5221 taccgataga tctaggttgg aagaagttat ttggcaaaga gagcgacgga aaagagaagg
     5281 aagaagagcc gctacttcct aaagtgacaa aaggagaaat ggtgacggta gatctacaag
     5341 tccttgaaaa agaaaccaag ccaccacaac cttataccga aggtacgttg atcactgcga
     5401 tgaaaacagc tgggaaaacc gtggatagtg aagaagcgca atccatattg aaagaagtgg
     5461 aaggaatcgg tacagaagcg acacgggcga atattattga aaccttgaaa caaaaggaat
     5521 atatcaaggt agagaaaaat aagcttgtgg tgacgaataa aggggttttg ctttgccaag
     5581 ctgtggaaaa agagccgctg cttacgagtg ccgaaatgac cgccaaatgg gaaagctact
     5641 tgttaaagat tggagaacga aaaggaacac aaaccacttt tctagccaat atccaaaagt
     5701 ttgtctctca cttattggaa gtcgtcccag gacaaatcca atccattgat tttggatcga
     5761 cgttacaaga agtgaaagca gccagtgaaa agcaagaagc cgcgcgtcat ttaggaattt
     5821 gtccaaaatg ccaggaacaa gaagtcttac tctatcaaaa ggtggcagct tgtacgtctg
     5881 aagcctgtga ttttaaatta tggacaacga ttgccaaaaa gaaactcaca gcgacacagc
     5941 tgaaggagat tattcaaaat agccgaacaa gccaaccagt gaaagggtta aaaggtcaga
     6001 agggttcgtt tgaagcaacg attgttttaa aagaagactt cactacaggc tttgaatttt
     6061 ctgaaaagaa aaaaacgaac ttcaagaaaa gaacacgacg cacgacaaaa taatggaggg
     6121 ttaatcttat gcgtaataca acacacaaac aacaagaaat cgaaaatcaa aaagccaaaa
     6181 ttcgttcaga acaagagaaa ttacgtgcca gtaaaagaag acttcagcaa ttaaagaacc
     6241 agcaacggat tcaaaaagaa atcgaattag atcgatagac attaaccttg ttacaaatac
     6301 actatcatga tatatttaat gtagtgtatt tgtaacaaaa ggggggaagt aaatgcaaga
     6361 gaaactgaaa gaattgttgg ctattcgcga tggaaattta tctatgaagg aagccagaaa
     6421 attaggaatc gcagcaacca ctgtacaaag attggtgaat caaggaaaat tgatcaaagt
     6481 tgatcgtggt tattatgtag aggatggtca tggaatagat gatttatttt ggcttcagca
     6541 acgtttttcc aggggaatct tctctcatga aacgacttta gatatttacc agctttctac
     6601 gaatatgccg aaattcattc acttaacttt tccccatgga tataacgttg atcgttcaat
     6661 tacaaaagag cagcagttac aatttcattt cgtgaagaaa gaagtttatg aactaggaaa
     6721 agtagaggga acttcctttc aaggaaatcc tattactatg tatgataaag agcgtacact
     6781 ttgtgatatt tggaatccga gatatgaaat tgaatatgaa atgaaattag aagcattaaa
     6841 agagtacatg gaagacccat tgagagatcc aagtaaatta agagattaca tgacaaaact
     6901 acatgtagaa aaagaaatga aataccacat gcaaagctta tattgatgga ggaaaaagat
     6961 gacaccgaca caatttgcag caaaaacaag aaatttagca aagaggacag gattaaatgc
     7021 acagttagta caacggcatt ttatgatgga tcgtttaatt gaacaaattt ctgaatctaa
     7081 gtataaaaat gatttcattt tgaaaggtgg ctttttatta ggatcaaaat atggaatcga
     7141 tagaaggacg acaattgata tcgacacgac atttagaaat agcaaattaa ctgaagaaaa
     7201 attgaagagt atttttaatg atttaactag gaaacccacg aaagaaggta ttgttttctc
     7261 tattcaagga atgaaggaaa caagagaagc cgatttttat cctggatttc aaattaaatt
     7321 ggtggctaat ttagagaaag tacgtgtgcc atttaaaatg gacgtgacaa caggagattc
     7381 tatttatcct gaagtagata cacactatca ccaattaatg tttgaagata aaaaggtgga
     7441 gattccagct tatccaacag cacaaattat tgcagaaaag ctaagtgcta cgttcagctt
     7501 tggcacagat aattcgagag caaaagatta ctacgactta tttaccattc cgaaactaga
     7561 aaatatcgat acgaaagagt tatacaaaag tgttcgaaat acatttacaa aacgtgggga
     7621 tacaaaaccg ttgtcctttt attatgaaag agaaatggat aagatcatag gaaatgacta
     7681 tttggaaaag cagtgggaaa aatatcgctc agttaacacg tttgcgaatt ccatttcatt
     7741 tacagataca gtcaacgaaa ttgatcacct aatgaaaagt gtgatcaaaa ttgaaaatca
     7801 agaaagaaaa cggcagttta aaagatcaca acaaatgaat caagaaatgg agagataaag
     7861 atgatcaata atgtaacttt agtaggacgc ttaaccaaag atccagattt acgttatacc
     7921 gcgagtggta ctgcagtagc gacttttacc ctagctgtca accgaaattt cacgaatcaa
     7981 aacggcaatc gagaagctga ttttattaac tgtgtgattt ggcgcaaacc agcagaaaca
     8041 atggtgacat tagctaaaaa aggtagcttg attggtgtag ttgggcggat tcaaacgcgg
     8101 acttatgaca accagcaagg acaacgtgtg tatgtgacag aagttgtggc cgataatttc
     8161 caactattag aaagcaaagc agcgacagaa agccgtgcgc acgctgatca atcgtccacc
     8221 agtccaagca ccaccacttt tgaacaacgg gatacagcga cgcctaataa caatggattg
     8281 aacgctttac agaatccatt tgggaatcca tttggtggac aatcaatcga tattagcgat
     8341 gatgatctac cgttctaagt agcattttct attggttgca tttgctacgg tttatgttat
     8401 aatttagtca acaaaaagaa ttttcaatct ataaccaaaa accactagct ggcgggctag
     8461 tggttttctt ttacgtttct attataagaa ttaacgggta ggcttactgt ctttcttggc
     8521 aaatttacaa tcaagccatt tgcagatata gtgcgcggct acttctgcca tgattgcaaa
     8581 aacaaaatca aaaagaattt tcaaacctat aacctcctcc ccttgccaga ttaggccggg
     8641 gtagcagaca gcaagactat tatagcataa ttgaaatatc caaatgattg gatttttgct
     8701 ataattttag cgaggtgatt gtgatgaaca aatatgttgg tttgcttgat aaaatccgag
     8761 taataaaaac gcaaccgtta ttggttcgct ttactttaca aacgattcat gaatcgatta
     8821 attgtgtagt tgcagatatt gaaattatcg ataaattgct aattatggat gatggaaaat
     8881 acaatattgc cgtcacaggt cacttcaata aacgaaatca gctagttatt gctagcatgt
     8941 atgttagaaa tcccgatcat tttacgcgat cgatgggcat ataaaaaaag aagagttgca
     9001 atcctaatgt aggactgcag ctctttttgt tttacataga aacaagaaaa atgaaaaggc
     9061 ctttttagga aggcgcgagc gccttctcaa ttgaaaaacc tctctcactc caaccgccac
     9121 cgccgttcga gaagaaagga agtgaacgtt gcacgttcac taagataaag ggtcttgcaa
     9181 agcaagacaa aatagaaaaa acttcctctc accaaaaggt tcgttcctgt tcgttatctc
     9241 tttattgatt tgccagaccg gcaacaagtt gccttttatc accaaaaagc gacaaggaca
     9301 agggtaaatg gcacgctgcg cgcccttgtc cttgtcgctt ttcgttgatt cattctggcc
     9361 aacaaatcaa taaagaaaga actaacgaaa ggaagtaaaa cctttcctaa gaggaggcag
     9421 aatcaatcat gcgaaagaaa tttgattatt ggggtgttcc cttcagcgaa ttattcccaa
     9481 actatcatgc accacatact gtcgaatgcg attgtggaca aagagcgaaa tgtatcaaaa
     9541 gctatcgttt gtatcaatgt ccaacatgcg gaaaaaaata caccttgtct tatggcgatt
     9601 atattttgat tgatgagaaa ggaaagaaac gctgatgaaa acataacata aattattgac
     9661 tgtaaaagaa gtcgttcaaa ttttggtgga caaagaagtc atttctgaaa aagtagcaga
     9721 agctttactt attccgcggt actggacgat agaaacccct ttagtagagg atgcaccgac
     9781 tatgctattt gaagacctag tgaagattgc aggatatgaa ctgcattatc aagaaaacat
     9841 ggaaacttat gaaaacgaat attggttaac caaattagag aactaaaaag gagaaaaaaa
     9901 tatggctcaa aattactatg acgaatttgt caaattacct ttggataaaa tggcacaaaa
     9961 aatggaggat atgacattcc tataccatga gacacgtgtt ccaaaaaaac attataagga
    10021 aagattgtcg gtagctgtgg aagaaatgat tgaatcaggt gtcgaaatga atctcattgc
    10081 gacgtactat cgaacactgg aagaactgaa aaaacaaaat gcaaaatggt ttttccaagc
    10141 cttactatgc ttggaagtag gtgtcaaacc aagcactatt aaaccttctg aatatcaagc
    10201 tttagaacta acgtatggga aatttgtcga aacgaaaaaa gccaagactg tttcaagtga
    10261 atggttagat tattttgaaa atatcaataa gtatggcgcc tattacacca tgaaaaagga
    10321 ggacaacgaa aatgaataag gtgatttatc aactaacaac ggaagatgtg tcacactttt
    10381 taacaaacaa agaacatttg aatgaagtaa tcagacggat tcaaaaagac tttagttgta
    10441 tggaagaaat gaagtacttt attcaaagag tcgaagaaca attgtatttg gaaagtgaaa
    10501 cgagtcaaac gaaggtcaca gtcagcaata attatttaga cgtgtataaa catcgtcctg
    10561 aaacggtaaa aaaaggaacg gagcttctac gactagaaac agaaaaatac atcatgaatg
    10621 tttacctaga aaggagtgaa ctggtcgaaa actttgtcag ctgcacgatt tgcaggaaac
    10681 actattactc agaatcagaa tattattcaa tttttgagag catggaatta atggaagaag
    10741 aaatggaaga gctaaacagc aaaaatgcga cgatagacga ttattatctt gtatttacta
    10801 gatttttgac gtgtggaacg gaatctatcg tgttaatggg aatggattat gaactcgctg
    10861 tacccgaagc atttttgagg gaatatgtag aagaagtaga taacccaggc gacgactggt
    10921 acacgacttt aactgatttt ttagatacct acacttacga cgatacagaa gaaatccaaa
    10981 atgaacttga ccgtaaacga atgccatatc aacgatttga aaggaaaaaa aggcaataat
    11041 catttatacc gaaaagtgag aatgtgtgaa ataagaacaa aaaccttgaa attaagggaa
    11101 tggttcttat ttcgcaccaa tcgctccaac cgcccccgcc gcttaggtgg tgcgaaataa
    11161 gcgggcaaag cccgataacc taagagaaag aaggagatcc atatgaataa aatcattcct
    11221 ctgttgttcg tactgtgtat tggcgagata cttatgcgtc atggtgcagc tgtacattta
    11281 aacttcgtag tattcttagg aatactagta ttttgtttga ttttttggcg ctttgtgtta
    11341 gcccttgtga gtctactatt caagttgatt gcagccatat ttttcatagg gttatttcga
    11401 tgaaaggaga gagtactaat gccaattgca ataggaaata aacggttacc cgtgacatta
    11461 gatgaaaaga gacaaaaaga attgcagcaa ctaaagcaga agtacggaaa aagtgaatct
    11521 aagattatgt gtattgcgtt agatctattg atcgcgcaag aaaaagcagg atttgatata
    11581 ccagcactaa aaaagtgacg tcacttttca tttgaagaaa caaaagtgat agcacttaat
    11641 tgttcctact atttagaata ttttctatgt cctttttatt ccattttgta tcaataacta
    11701 tgaaatcttt aaagtatcca gatcaatttt tttcttacct gattctaaag attttgtttt
    11761 cttaaacata ttatgatttc ctttcgacta ttttcatata aatgttaaca tagtttatgg
    11821 attcatggaa tgttaatcta atttaataga aaaggataat taagtatata cgttttttct
    11881 tatgtatgtt atactatgta tatacagaaa gaggtgtcta ctatggaaat gttacctata
    11941 aaaaaatggg gaaatagtaa tggccttaga ttgccaaagt atattatgga atatcttgga
    12001 attcatacag aagacaaagt gaagataata caagaagaag taaacggtca gaagcggcta
    12061 attatcgaag cggctaatat agaaaatgaa ttaacaattg aacagttatt tgaaaattac
    12121 actgatgaaa gaaatcatgt gacgattcaa aatttaggtg aagcagtagg taatgaaaaa
    12181 tggtgagaaa acctagacaa ggcgatattc tattattgaa tacagcacct cgatctggac
    12241 acgaacagac aggtaaaaga ccttatattg ttttaagtca tgatattatt gcggattata
    12301 gtaacgttgt tacagttgct ccaatttcta gtacaactag aaactatccg ctatatgtaa
    12361 atataaactc agaatatgaa atgaagacaa caggaaaagt attattagat caactaacga
    12421 caattgatta tgaagccaga gagtgtattt ttttggaaaa agcgcatgat agtttagttg
    12481 aggagttatt gatgaaagtt agaacagttt ttcaaaaagt aagcaaataa aatagaaaca
    12541 gcagcatgat caactattcg tgattgacca tgctgtcttt ttttattcta tatacggttt
    12601 gtctcgtaac attgtagtct tttgcaatct tagcgatcgc aacacctttt tttagatcct
    12661 caacgatgtt tttataaaca agacgacgtt ggggatcttt tgcattggca ctgtatagct
    12721 taggacgtcc tttataaaca ccgttcgctt ttgcaatctt aatgccttgt gcctgacgtc
    12781 gtttagattc ggtacgttct tgttcagcga tcatggccaa aatttgaatg atcaaatctt
    12841 taatgaattt atccaggaga ggattgccaa ttgcttcggc catgatcggt agacttgtga
    12901 tgatcagctg cacatttttc ttcttcaagt aattgactga agcgatgatc tcgtcgtaat
    12961 ttcttccaag tcgatcaata gcttccacaa taaaaatatc ttgatctcgg acgaaatcca
    13021 gtgcttcttg aaaaacaggt cgatgagtaa tcgttgcgcc agattgtttc tcaatgaaaa
    13081 ttctctctgc accgaatttt ttcatttctt caatctgccg ttgttcattt tgatcgatgg
    13141 atgagacacg tatgtatgca actctcaaaa tttttaccta ctttctgcaa ctatttaaaa
    13201 aacaccctaa tcatacacga gaaaaccaga tttttcaatg tcgcggtcgt gtctagttag
    13261 ggtatacctt atatagacaa aaactaatga tggaggaaat agtatgtgtc acttttcttt
    13321 ttaaatggca atattttttg taaataaatg tcaatcaaga aaatttaaac gattatgaca
    13381 ttaaaaatat attttatgaa ttttctagta tataacttga tttatctgtt aagatttatt
    13441 aagaaaacgt tttcttattt ttgatttcga ggtgatagac aatgaaaaat aagtttattt
    13501 tatctttagg tattttaact attggaatta gtgtaactgg aactacaatt cctacatttg
    13561 ctgatagtac aaatgaacca actactgtag tagataataa ccaagaatta actcctttag
    13621 ataggaacgg aatagccatt ggtaacccaa ctaacgactt aactgttact gaaaattatt
    13681 taatagtttc tccattactt gctcgagcag cttctaaaac gatacgagtg acaggaacga
    13741 tgatttttga taaagttggt tggccttcta gacctcctca atcacggaat tggaaagaaa
    13801 aaagaaatgg ttattggtac tatggaaaat tgtatttaca aagttataaa tcagctggaa
    13861 acaattggat tgcgacttat tcaggaacct taactagaaa gtagggattt tttatgccag
    13921 aatttgtgaa cacaccaaat ttttatcaag atagcgatat tctaagtaaa attaatttac
    13981 cgaaagaaga atcagcttta caagttcagc gaactttaca ggagacacaa aaaattcaaa
    14041 aatcaatttc taatctagaa gattctgaag aaaaaagaaa aaaaagagac caaaaaacat
    14101 atcaaaaaga aaaataatga ttttaaaaaa agagtgtcta gtcgacattc tttttttcta
    14161 attgaaagtg ttcataaaat cacccatttc tggacacttt ctttttttgc tttatttttc
    14221 aaaaaaacaa ttcatttcat gttcataaac ccataacaat atctatgttc agttaaacta
    14281 tatggataaa gttatgttac aataaaatta atgaaggagt gatttttttg aaaataggat
    14341 acgcccgggt atctactggt ttacaaaatt tggatttaca agaagacagc ctaaataaat
    14401 ttggttgtga aaaaattttt actgatcata tgagtggggc aaaaagtaat cgaccaggat
    14461 tagaaatggc cattgatttt gttcgctctg gcgatacact tgtcgtttgg cgcttagatc
    14521 gtttaggtag aaatatggaa gatttgattt caatcgtcaa tcgactgaat gagcgtggtg
    14581 tgagttttca tagtattcaa gaaaatatta cgatggacaa atcaagttct acaggacagc
    14641 tcatgtttca tttgtttgcg gcatttgcag aatttgagcg taatttgatc ctggaacgat
    14701 ccgcagcagg acgagcagct gctcgtgcaa gaggacggtt tggtggtcgt cctgaaaaat
    14761 tgtctgaaca agatttggaa ttactgaaga ctttagtgga tagcggtaca cctattaaga
    14821 ctattgcgga acggtggaac gtctcaagaa ccaccattta tcgttatttg gcaaaaatgg
    14881 aggagaaaaa tggaaagaca aattctcatt agtttttgtc atttaatgct gaaaattttt
    14941 gccatttatc tagaaaagtg acaatagtat gagaattttt tgtaagtgtc tactgataac
    15001 ttattctcaa atgttgtaag gattttattc atttgttaat attaaagaac ggaactccaa
    15061 aaaagtccgt actctaattt gcagtctctc actcttttag agtgagagtt tttattagat
//
LOCUS       DBBGSP010000068        14820 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000068 DBBGSP010000000
VERSION     DBBGSP010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.068"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(296..1024)
                     /locus_tag="ACIZE9_002519"
     CDS             complement(296..1024)
                     /locus_tag="ACIZE9_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094337.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="ACIZE9_002520"
     CDS             complement(1002..2576)
                     /locus_tag="ACIZE9_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HGC6094338.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="ACIZE9_002521"
     CDS             2805..3743
                     /locus_tag="ACIZE9_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6094339.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="ACIZE9_002522"
     CDS             3755..4666
                     /locus_tag="ACIZE9_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6094340.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="ACIZE9_002523"
     CDS             4690..6162
                     /locus_tag="ACIZE9_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC6094341.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6213..6824
                     /locus_tag="ACIZE9_002524"
     CDS             6213..6824
                     /locus_tag="ACIZE9_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGC6094342.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6854..8767
                     /locus_tag="ACIZE9_002525"
     CDS             6854..8767
                     /locus_tag="ACIZE9_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HGC6094343.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8895..11876
                     /locus_tag="ACIZE9_002526"
     CDS             8895..11876
                     /locus_tag="ACIZE9_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="HGC6094344.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11873..13534
                     /locus_tag="ACIZE9_002527"
     CDS             11873..13534
                     /locus_tag="ACIZE9_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein O-GlcNAcase"
                     /protein_id="HGC6094345.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13574..14506
                     /locus_tag="ACIZE9_002528"
     CDS             13574..14506
                     /locus_tag="ACIZE9_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGC6094346.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4818 a         2333 c         2979 g         4690 t
ORIGIN      
        1 atttaaataa ctacatccat ttattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa
     6181 gaatagacta agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat
     6241 ttaattgggt ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag
     6301 gatttggaat tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc
     6361 gaaaaaaata tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt
     6421 ttgttagata taatctatat tgctggtcag caactttgtt gttggccggc aatattacta
     6481 cgatctggct ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat
     6541 cggtaattac actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg
     6601 ggttgtggat gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc
     6661 caacggtagt catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc
     6721 ctgtgatttt tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg
     6781 aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg
     6841 agtatttctt tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca
     6901 acttgagatt ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac
     6961 aaaggctaat gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc
     7021 ttattcacat gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc
     7081 tcaaggagga gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt
     7141 agatgcttct cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt
     7201 agcgttgatg gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga
     7261 ccttccatat tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt
     7321 tgaatttgct tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt
     7381 gacccaattt ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact
     7441 gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat
     7501 gtatcagaca gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg
     7561 atatttaagc ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg
     7621 tgtgttatca attgttgata aatataagat gaaaccaatg atttggagtg atttcattta
     7681 taagctatta gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc
     7741 attagcagct aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga
     7801 tgaagtttcc tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca
     7861 ttacgtttta gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac
     7921 agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat
     7981 gttaactact tggggagatg aagggcagga aacagagcat tggcattcct taattggggc
     8041 attaaaatta gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta
     8101 cgatcgttta ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga
     8161 agtggatacc attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg
     8221 gcaagatccg ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac
     8281 tagaacaatt ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg
     8341 gaatccaaaa caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat
     8401 tttagcacaa aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct
     8461 tgcaggatta atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt
     8521 ggcatctatt catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt
     8581 agaacaacga tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa
     8641 tcatcttcag gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca
     8701 atatcaagtg ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta
     8761 caattaacga aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt
     8821 tcgttttcta ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta
     8881 ggaagtgaga aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata
     8941 cagaaccatt acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt
     9001 tagaaaggga aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt
     9061 atccttctgt ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg
     9121 atagaatttc tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca
     9181 atgtatctta tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg
     9241 tatatcggcg tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag
     9301 gagcagatag taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga
     9361 gtcatagtac atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc
     9421 aaattctagt gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa
     9481 tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt
     9541 atcaactacg gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc
     9601 aacgatttac tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg
     9661 gacgtctcat agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag
     9721 attgcctttt ttggacagca gaaacgccta aattatatac attactttta acatgtaatg
     9781 gtgaatattt taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat
     9841 tgctgaacgg aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag
     9901 gcacgccagt gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa
     9961 atgtgaatac tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg
    10021 atgagattgg tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc
    10081 tatatgatac tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga
    10141 ttatggaccg agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt
    10201 ggtctatggg gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac
    10261 ggaaattgga tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc
    10321 aagtgaatga ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg
    10381 ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc
    10441 acgctatggg caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg
    10501 attcctttct tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt
    10561 tagaaacgcc atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt
    10621 tttgcgtaga tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc
    10681 gtaatattca ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct
    10741 tgagcaatat aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata
    10801 tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa
    10861 gttgttcatt gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt
    10921 cgctatctgt ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag
    10981 aaaaaatgag attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag
    11041 gcacagagct gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg
    11101 cgttcacttc tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa
    11161 tttggcgtgc accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat
    11221 atgctgaaat gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc
    11281 tgatcgaaac gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca
    11341 tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc
    11401 cgatttttcc agatttccct cgctttggga tggactggcc gttgaatgat actttttcga
    11461 aggtttctta ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga
    11521 tgtttggtat ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag
    11581 aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca
    11641 tgacggttta tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg
    11701 aaaagtcaca ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata
    11761 aacaaaatgg tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta
    11821 tggaagatac ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga
    11881 aacaaagatc aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa
    11941 ccattgctta aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg
    12001 tttcgaacag ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca
    12061 gctcataaat gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca
    12121 tttgaaaaat gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc
    12181 agcaaacctt cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt
    12241 aggagatcaa ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg
    12301 aggaatcatt gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt
    12361 ttcatatatg aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt
    12421 attacgtaaa aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct
    12481 tttatctgct gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga
    12541 tattgatatt acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat
    12601 tgagcttggc gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg
    12661 tgctgctaaa cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt
    12721 agaggaatat cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata
    12781 tgataatcgt catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt
    12841 accgttcttt tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca
    12901 ggaaatggct tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga
    12961 ttatttagag gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct
    13021 ttctaaggag agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc
    13081 ttcaaagttt acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc
    13141 tttggaaact tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta
    13201 tcttacctta accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga
    13261 attactgcta gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc
    13321 agtaaaatgg atccagcaag aacaacatac atctagattg agaacagaat tggagccttg
    13381 gttacaagca atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc
    13441 aaaagaagca gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt
    13501 aactgcccat ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa
    13561 aaaggagaac aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat
    13621 gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga
    13681 aacggttgct aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc
    13741 atttggtgca gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg
    13801 actaccaaat gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat
    13861 tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc
    13921 taaaacaaat atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga
    13981 aacgatacaa aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg
    14041 cactggagta accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc
    14101 gggattgatt attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa
    14161 agaggcgatt atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg
    14221 gtctatccca ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata
    14281 tgatttgtta acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt
    14341 gcggcaatta gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc
    14401 tggatacggg ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg
    14461 aatgcgacat accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa
    14521 aaatggttaa attgattatt taagtgggaa catacttgag atatcagcta acttctgtca
    14581 ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact
    14641 aggatagcag aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct
    14701 cttattgttc ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta
    14761 ggaaaaatgg tagggaacca tatcattttt aatgaaaatc aagcatttca aaagttgaaa
//
LOCUS       DBBGSP010000069        14416 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000069 DBBGSP010000000
VERSION     DBBGSP010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.069"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(146..1111)
                     /locus_tag="ACIZE9_002529"
     CDS             complement(146..1111)
                     /locus_tag="ACIZE9_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGC6094347.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            1345..2190
                     /locus_tag="ACIZE9_002530"
     CDS             1345..2190
                     /locus_tag="ACIZE9_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC6094348.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            2381..3568
                     /locus_tag="ACIZE9_002531"
     CDS             2381..3568
                     /locus_tag="ACIZE9_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGC6094349.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            3574..3930
                     /locus_tag="ACIZE9_002532"
     CDS             3574..3930
                     /locus_tag="ACIZE9_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGC6094350.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            3932..4270
                     /locus_tag="ACIZE9_002533"
     CDS             3932..4270
                     /locus_tag="ACIZE9_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HGC6094351.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    4346..4602
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4665..5699
                     /locus_tag="ACIZE9_002534"
     CDS             4665..5699
                     /locus_tag="ACIZE9_002534"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGC6094352.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            5692..6378
                     /locus_tag="ACIZE9_002535"
     CDS             5692..6378
                     /locus_tag="ACIZE9_002535"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGC6094353.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            6402..7250
                     /locus_tag="ACIZE9_002536"
     CDS             6402..7250
                     /locus_tag="ACIZE9_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGC6094354.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            7447..8220
                     /gene="sufC"
                     /locus_tag="ACIZE9_002537"
     CDS             7447..8220
                     /gene="sufC"
                     /locus_tag="ACIZE9_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGC6094355.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            8233..9519
                     /gene="sufD"
                     /locus_tag="ACIZE9_002538"
     CDS             8233..9519
                     /gene="sufD"
                     /locus_tag="ACIZE9_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGC6094356.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            9516..10751
                     /locus_tag="ACIZE9_002539"
     CDS             9516..10751
                     /locus_tag="ACIZE9_002539"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGC6094357.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            10738..11208
                     /gene="sufU"
                     /locus_tag="ACIZE9_002540"
     CDS             10738..11208
                     /gene="sufU"
                     /locus_tag="ACIZE9_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGC6094358.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            11213..12604
                     /gene="sufB"
                     /locus_tag="ACIZE9_002541"
     CDS             11213..12604
                     /gene="sufB"
                     /locus_tag="ACIZE9_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGC6094359.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(12702..13844)
                     /locus_tag="ACIZE9_002542"
     CDS             complement(12702..13844)
                     /locus_tag="ACIZE9_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6094360.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(13895..>14416)
                     /locus_tag="ACIZE9_002543"
     CDS             complement(13895..>14416)
                     /locus_tag="ACIZE9_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGC6094361.1"
                     /translation="PEIPHKVFKDIQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDF
                     EIYLNEILANNINPLIEEYANQRHSISKELFFKRANSKLQDKIRNGDFKYGEKERMID
                     SLKQLLDEMDLAYKDISKYSSVEDFFYKITKNQFETEKFISDLSKKYNFPYEKNSIIA
                     KFLTDNHDKFKNN"
BASE COUNT         4679 a         2640 c         3075 g         4022 t
ORIGIN      
        1 ttacgacctc ttggtaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaaccag
       61 tacaaaaaca tgaacagctg tttttgtttg gccgttctta ttacttgatg cagaacagct
      121 ttttcacaac ctattgaatc gattattaag cgattttttt agaaacaaat tttccatgtt
      181 tgctatgttc tttaattaag aaacgtacgt aatgagcaag aacgtagaag acaactacac
      241 ttgcaaacag acattccgca acttttaaga aatccaatac gctactatag atacctaaac
      301 tgttgaagta atgaacagta gtaaatatag ctgttgcaga gataacaagc gggaatgtaa
      361 aggctgcata gcttggataa aaacgaagct tgaacaaacg tggaagcata gacagcacaa
      421 cgaaatacaa tacttgagat aaagcgaaca atgctacgac aagataaaaa ttaggttcag
      481 caaagttttt aagataacct gttaggcaaa gagaaccagg tgctgcaacg atcgtaatca
      541 gcggacgtgt cggatgagcc atatttctta cgaaaaagac acgtttgatg atgatcggca
      601 ataagaacgc atagcagatc aatgaaatcc aaaagaaaat ttttccaata agtgggaaga
      661 agttcccggc agttacagtg atgaccccaa atccaacgta aatgataaac cagcttggat
      721 aaattgcttc aattgaaaga tcagctttga taacatggtg ataattgaaa taaaagacaa
      781 ggatcacttg gaagataaca gcgcacagcc aaatgaattt gacaattggt gcaatacttt
      841 catatgaaac aaaataagta caaataacca tgagtgacat cgtaaaagtt ggtgaaacgg
      901 aggcgatgat tggatcatgc aacgtttgtt tcgtgtgttc gaataagata aacaatttaa
      961 caaaaatgaa tatcataaga atcatagaga taccgccagt tagattgcct aaagcaacat
     1021 ggtgatagtc tttaaacaga tttccaaggg aagctaaccc aaggatcaac ccgcagatcg
     1081 ggatcggaat aattttcaaa aagttcttca tatataatat tctccttttt atttaataga
     1141 ttttagtacc aagatgaacg aatacattgt aaaatgaata ggaatgtatg attacgagca
     1201 agcagacagc tgattgtctt catctaagtt actagttgga tcagcaactg ttttgttgta
     1261 catttctatt atagatggtt ttttgtatat ttaaatcaaa tagtttttat agtaattatc
     1321 ataaaaagtt atggaagtgg tgccatgttt aagttattaa cgacttttcg agcagtatat
     1381 gaaacaagaa atttttccag agcagcagaa gtactgtttt tatctcaacc agcagtctcg
     1441 aatcaaatca aacagttgga gcgggaattg aatatcgatc tttttcaacg taacggaaga
     1501 aaagagatgc ttccaactaa gcaagccgac ttattatatg aacggacact ggttttgtta
     1561 gaagaatggg aagaaactca gcaaaaattg ctcaatgaac aaaatgaaga agaagtatgt
     1621 cggatcgttg cttcccacac ctttgctgtc tatcttttgc ctcagttgat gaaacatctg
     1681 atcaaaaggt ttcctaaagt gcattttgag atcgaaatca cgaattctca tgaatcatta
     1741 gaacaagtag cgaaacatga atccgatttt ggttttatcg aaaagccatt agagacttcc
     1801 ggcgtacaaa gatactcttt gatggaagac cagctagtca tcgctgggga cccaaaaagc
     1861 aaattgtggc ttgtaagaga agcaaactct ggtgtttttc attacacgca gcgttatttt
     1921 gaagagatga atatccaaga taagaagatg atcgtgaaaa gtaacgatgt aattgttgcg
     1981 ttgctgaagg aaggaatcgg tcgctcgatt ttgtctaagc gctctgttcc agaaaatgtg
     2041 ccaatgactc cgttgaattt ccatcgatat ttttatttca tccaacgaac caatctggtt
     2101 tctgatcagc tgctagagat tgccgaagag atccttcgat acaatgaaag cacagaaact
     2161 tctcacagcg aggagaatct cagctggtag ataattgcat gtatcaaaaa aagttctatg
     2221 atacactaaa gataagcagt aggcttttgt actgcatttg ctcaagcaac tgcacaaacg
     2281 gaaagttaat ttttcccaaa tgtctatgga aagactttcc attatctaac tggaccgcta
     2341 taataatcag cagtatggtt tttaagaaaa gggatgaaac atggaaaaaa aattaaaagc
     2401 ttcgaacgat aatcgtattg attatggcgt gattttacca gtctttctgt tatgtttgat
     2461 tggtctgctc tcattatatg tagcacttag ccatgatccg aacaatccag cagtcttgaa
     2521 aggcgtaggg atgcaagttg tctggtattt agttggagcg gcagcaatcg ttgtcatcat
     2581 gcatttgaat tccaaatgga tctggaaact gactccttac ctttatggtt tggggttagt
     2641 ggtaatggga ctcttgctca aattctatga tcagaattta gctgcttcaa cagggtctaa
     2701 aaactggttt cgattcggtg cgtttacttt ccagccagca gagttgatga agattgcgta
     2761 catcttgatg atggcactga tcgtaactaa acataatacg caagtaaaag aacggacgat
     2821 gaaatcggac ttttggctga ttgggaagct cttgatcgtg acaataccgg ttttagcatt
     2881 gatcatggcc caagatgact ttggaacgat gcttgtcttt cttgcgatct ttggcgggat
     2941 tttcctgatg tctggaatct cttggcgcat catcgcacct gtagtaatct tggcagtagt
     3001 cgttggagca ggaacgatct tcttggttac gactgaaggc ggaagagact tgctttataa
     3061 agttggattc aaatcttatc agtttgcacg tattgattca tggctggacc ctttccatga
     3121 tacgtcagga atgagttatc agccggccca aggacttttg gcaattggta ccggtggctt
     3181 gtttggtaaa ggattcaacg taagcaatat ctatgtgcct gttcgtgagt ccgatatgat
     3241 ttttaccgtt atcggtgaaa acttcggctt tatcggtggt gcattcgtca ttttcttgta
     3301 ttttatttta atctatcgta tgattcgggt gtgtttcgat acgaataatg aattttacgc
     3361 ctatatcgca agcggtttga tcatgatgct gctgttccat gtctttgaga atattggagc
     3421 aaatatcgga ttacttcctt taacagggat cccattgcct ttcattagtc agggaggatc
     3481 ctcgatttta gggaacatga tcggtatcgg gttgatatta tcgatgagat accaaaatga
     3541 agcacctgca agatcttcaa ggaggtaaga aaattgtaca ccttttactg gtacccgaaa
     3601 tgttcaacat gcaaaaaagc caaagcgtgg ttagaccagc atggcgttag ttatcaaacc
     3661 gttgatatga tcaaagaagt accgaaggcc tcaacgattg agacttggct agaaacgagt
     3721 caagtaccaa tccgtcgcct gttcaacaca agcgggatga aatatcggga acttggactg
     3781 aaagatcaag taggcgagtt tacggcttca aaagcgagcc aagtcttatc gacagatggt
     3841 atgctgatca agcgaccact gatcttacga gaggaccagc ttgttgcaat tggattcaat
     3901 gaaaaaattt atgaaggaga actgatataa aatggcaggc aagcatttga agaaaaagga
     3961 caacctttgg atcttattta atggaaaaga atactgtgtt ggtttgacaa atgaagcgca
     4021 agaagaactt ggagacatca cgtttgccaa tctgccaaaa gcaggacaat cgctaaaaaa
     4081 agatgaacct ctgatcgaag ttgaagcgga aaaagcggtc aatgaatttg ccagcccgct
     4141 aacgggtaca gtttcttctg ttaatgataa aatcggtgaa gatatcaata tcttgaatga
     4201 ttcagatgaa atgaatgcgt ggatcttaag tttcaaagat gttgatccaa aagaatttga
     4261 cgaattataa aatcagaaaa tcacttgaaa aaagttgaca ctgattcttc cagttgctat
     4321 aatcataagc aatcctatat gaaacgagaa agctttgaaa agaagagtac atgtcacgga
     4381 cgtttgaaga gagccctgtt tgctgaaaat gggtaacgaa aatgagatgg aagatggtct
     4441 tagagcagag taagcgagcg taagcaaact tactacggga gtgcccgtta cagcgcgaca
     4501 gtatacggaa agaagctaag tccaagtact ggaagaggct gttattgcga agtaacggta
     4561 aatcaaggtg gtaacacgga agttcaagct ttcgtccttt tgcttaaggc aagagggcga
     4621 aggctttttt gtttgaaaaa ttataagaga aagatgtgaa tggcatgtca ttaatccaac
     4681 taacgaatgt caaaaagaca ttcaatggga aaaacggaaa catccaagcc gtcaatgacg
     4741 tttcactaaa cgttgaaaaa ggggatattt atggaatcgt cggctattct ggcgcaggaa
     4801 aaagtacatt agtccgtctc ctgaatggac ttgagcttcc cacgagcggc gaagtgatcg
     4861 taaacgatca agatattaca aaattaaaaa acaaagaatt acgtacattc cgaaagaaaa
     4921 tcggtatgat cttccagcat ttcaacctgt tatggtcaag aactgtactt gaaaatatcc
     4981 agctgccgct ggaattagct ggcgtaccaa agagcaaacg taaagaacgg gcagaagaac
     5041 tgttgcgttt agtcgggtta gaaggacgcg gacaagcata tccttcacaa ctttccggcg
     5101 gacagaaaca acgcgtcggt atcgcacgag cattggcaaa tgatcctgag atcctgcttt
     5161 gtgatgaggc tactagcgca ttggacccgc aaacaacaga agaagtatta gacttattgt
     5221 tagcgatcaa taagaaattg aatttgacca tcgtcttgat cacacatgaa atgaatgtga
     5281 tccgcaaaat ctgcaacaaa gtcgctgtga tggagttggg gaaagtcgta gaagaaggag
     5341 acgtattgac tgtcttcaga caaccgaaaa aagaagtaac caaacgcttt gtacaacaag
     5401 acatcgaacc agaagctgat tcgacagaac tattagctga actcatcaaa gaaaatccaa
     5461 gcggccgttt ggcaactttg acctttagcg aaagaaatgc caacgagcca gtcatttccc
     5521 aagcgattcg acgctataac atcgatgtca acgttgtgta tggaaagatc aaacaagtga
     5581 aagaaggttc ctttggttca ttgactgtct tgatgactgg tgaaaccaaa gaattagatc
     5641 aagcagaagt gttcatcaaa gaacaaggag taggaattga ggtgatccat cgtggataaa
     5701 agcttttcag aaacatatct agattttaaa caaatcaacc cggaaacgat gaatcaggct
     5761 atccttgata cactatatat gacattaatc tcaatggtct tagtgacgat catcggatta
     5821 gttttgggat tgatccttta ctctattgga cgcaaaaaca aaccgtatgc tcgaatcatt
     5881 tatggaatcg tatcgatcat cagtaatatt ttccggtcaa cgccatttat gatcctgatg
     5941 gttttgatca ttccatttac taaagcaatc gtaggcacta tgctaggtgc gcaagcagcc
     6001 attccagctc ttgttttatc cgcagcacca ttttatgccc gtctagtaga gattgctttt
     6061 cgtgaagtca gccctggtgt actggaagca gcagatgcaa tgggagcaag ttactgggaa
     6121 atcatctgga aggtcttgat acctgaaagt attcccgcat tgatttctgg attaacagtt
     6181 acaacgatct cgatgatcgg atttactgcg atggccggcg cgatcggcgc aggtggactt
     6241 ggaggtcttg cttggcagga aggctaccag cgtggtaatc taacagtgac attcgttgcg
     6301 actttaatta ttttactaat cgtatttatc gttcaaggaa tcggtgattt cttaactaag
     6361 aaaacagaca aaagataata ggatataggg ggatgtagga tatgaaaaag aaaatttttg
     6421 gatttgcagc agcgcttttg ctgactgtag gattagcagc atgcggtaac aacagcgaca
     6481 gcaaagattc agcaaataaa gcagacgaca cgacattgaa agtcggcgct tcaccgacac
     6541 cgcacgcaga gattttggaa catgtgaaac cattattgaa agatgaagga atcgatcttg
     6601 aaatcgtcaa attcgatgac tatgtattac cgaaccaatc tttggaagaa ggcgacattg
     6661 atgccaatta cttccagcat attccttatt tgaacaaaga aatcaaagaa aaaggatatg
     6721 actttgtcaa tgccggtgct gtccacatcg aaccaatggg cttgtactct aaaaaagtca
     6781 aagatgtttc cgaattaaaa gatggtgcaa caatcattac ttcaaattct gaatcagact
     6841 ggggacgcat catcacaatt ctacaagatg ctggcttagt caaagtcaaa gatggagtag
     6901 atctggaaac agcaacattc gatgatattg aagaaaaccc taagaacttg aagttcaacc
     6961 atacgatcga cccatcactt ttagcttcta cgtaccaaaa tgatgaaggt gacctagttg
     7021 caatcaacgc aaacttcgct tacggcgcag ggttgaatcc attagaagat gccgtattgc
     7081 ttgaaaagga caactctcct tacgtgaata ttattgcgac tcgtaaaggt gatgaagaca
     7141 gtgacaaaat caaaaaactg attgaagtgc ttcaccgcaa agaagtccaa gaatggatca
     7201 cagacaaatg gggcggctct gttaaaccag taaaggctga tgcaaaataa ggtatggaac
     7261 aaaaaagatg agaaataagt ctgtaatggc ttatttctca tcttttttat acctattcta
     7321 atttagaaat caaaattgtt taataataaa taaaagatat ttgattttag taaggaaggt
     7381 cattgcgctt cattctcaat tagtctaaaa tgagtgagaa cgaaagagaa tttgggggta
     7441 taatgcatgt ctgtcttaga aataaaaaat ctacatgtgt cgatcgagga aaaagaaatc
     7501 cttaaaggcg taaacctaac aatgaaaacc ggagaaatcc atgccatcat gggacctaac
     7561 ggcacaggaa aatctacctt atctgccgct atcatgggca atccaaacta tgaagtaaca
     7621 gaaggcgaaa ttttgtttga cgggaaaaat gttttagact tggaagtaga tgaacgtgcg
     7681 cgacttggct tatttttagc tatgcaatat ccaagtgaga taccaggtat cacgaatgcg
     7741 gaattcatgc gtgcagcgat caatgcgaaa cgtgatgaaa acgacaaaat ttctgttatg
     7801 gcatttttga aaaagttaga tgaaaaaatg gctttactaa atatgccaga agaaatggct
     7861 gaacgttatc tgaacgaagg tttttctggc ggagaaaaga aacggaatga gatcctgcaa
     7921 ttgttgatgt tagaacctac atttgcaatt ttagacgaaa tcgattcagg tctggatatc
     7981 gatgctttga aagtcgttgc taaaggagta aatgaaatgc gcggagacaa tttcggtgca
     8041 ttgatcatca cccactatca acgattattg aactatatca cacctgatgt cgttcacatc
     8101 atgatggaag gccgagtagt catgacaggg aatgctgacc tagctaaacg tctggaagca
     8161 gaaggctacg ctggtatcag taaagaatta ggaatcgact ataaagaaga agaagcgtaa
     8221 gggggagcaa gaatgaaaga aaaaaactgg ctcgattatc ttgacgcggt aaatgatttt
     8281 tctttaagta aaggcgaacc tgattggatg agaaccttcc gtcaagacgc actagcgaaa
     8341 gcagatgaac tgccattgcc gcatatcgat cgggtgaaat tccatcgctg gtcgttattt
     8401 gatgtgaaag aaacacaaac catcagtgaa acaggcacga ttccggcatt tgatgcaatg
     8461 aaagacaatc ctgtgcttgt ccaacaaggt tcatggacga tttttgaaca actgcctgtg
     8521 gaattagcag aaaaaggagt catttttacc gacttgttca ctgcaatgat cgaatatcca
     8581 gaactagtcc aagaatatta tatgaaaaaa gcagtaaaca tgaacgaaga ccaattgact
     8641 gcactccatg tagcttttat gaacagcggt attttcctgt atgtgcctaa aaatgtcgtg
     8701 atcgatgaac cactcgagtc cttattcatt caagatggcg catccgatga gcacttcttc
     8761 aagcatgtgt tgatcgtggc agatgaacat agtgaatttt cttatctgga acgtttccag
     8821 acaaccaaag aacaagtagc aaaatcatca ggtaatatca tcgtggaagt catcgctaaa
     8881 gctggttcaa aaatcaaata ttcagccgta gatcaattag gagaaaatat tacttcttat
     8941 atgaatcgcc gtgggcacat tttacgagat gcttctgtcg actgggcaat tggtgtcatg
     9001 aatgacggtc atgtgatcgc tgactttgac tcagatttag caggagaagg tgcacacgca
     9061 gaagtcaaaa tcgtggcaat cagctcgggc agacaaatcc aaggaatcga tacacgagta
     9121 accaataaag cccctcatac gatcgggcat attttgcaac acggagtgat ccgagaaaaa
     9181 ggaacattga cctttaatgg tatcggccac atcttgaaag gggcaaaagg tgcagatgcc
     9241 caacaagaaa gtcgtgtctt gatgctttct gataaagcac gtggtgatgc gaatcctatt
     9301 cttttgatcg atgaaaacga agtaactgct ggacatgctg ccagtgtagg acgagttgat
     9361 ccagaagaaa tgtactatct gatgagtaga ggattgcata aagaagaagc agagcgctta
     9421 gtgattcgag gattcctcgg ttctgtctta acagcaatcc ctgtagaaca agttcggaaa
     9481 gaattagtcg aagtaatcga agggaagttg aatggatgat cgatgctaaa aagctacgca
     9541 atgattttcc tatcttattt caagacgtca atgatgaacc tttagtttat ctggataatg
     9601 cagcgacgac ccaaaagcca aaacaagtac tccaggcatt agcgtactat tacgaacacg
     9661 ataacgccaa tgttcatcgc ggtgtccata cgttagcaga acgcgcgacc catgattatg
     9721 aacaagcaag agaaaaagta cgggcgttca tccatgcaaa agaaacagca gaagtgctgt
     9781 ttactcgtgg tacgacgaca agcttgaatt gggtagccag aaccttcggc gaccgctata
     9841 tcaaagcagg agacgagata gtgctctctt acatggaaca tcattctaat gttatcccgt
     9901 ggcagcagtt ggcaaaacga acaggtgctg tcttgaaata tatcgaacta acagaagaag
     9961 gcttcctgga tatggaggat gcagcgaaaa agattacgga caaaaccaaa atcgtctcca
    10021 ttgctcatgt atccaatgtc ttaggtgtct tcaatcctgt tcaagaatta gctgaacttg
    10081 tccatgaaaa cggcggggtc atcgtagtag atggtgctca atctgccccg cacatggcca
    10141 ttgatgtcca agcactagac tgtgatttct ttgctttcag cggacacaaa atgtgcggac
    10201 caacaggtat tggtgtttta tatggtaaac gaaaatggtt agaagaaatg gaacctgttg
    10261 aatttggtgg cgaaatgatc gattttgtcg aattatacga cagtacatgg aaagaactac
    10321 cttggaaatt cgaagcaggg acaccaaata tcgccggcgc tatcgcatta ggccatgcaa
    10381 tcgattattt gcaaaaactc ggtatggaca atatccatcg atatgaagaa gaactagccg
    10441 cttatgtgtt gccaaaatta caagcaattg atggattgac tgtttatggt ccacaagacc
    10501 cgaattttcg gacaggagtc gttgcattca atttggatgg gttacatccc catgatgtcg
    10561 cgacagcttt agacatggaa ggggtagccg tcagagcagg tcatcattgt gcgcaaccgc
    10621 tattgaagta ccttgaagta tcagcgactg ctcgcgcgag cttttatttc tacaacacaa
    10681 cgcaagacgc cgaccgttta gttgaagcaa tcatggcaac aaaggagttt ttccaacatg
    10741 ggactatcta aattagacaa tttataccgt caagtgatct tggatcattc ttcccatccg
    10801 catcatcgtg gaagcttgac tgactcgaca agcaagatcg aattgaacaa ccccacatgt
    10861 ggagatgtga tcgaattgca agtcgatgta aaagacggaa tcatcaaaaa tatcgccttt
    10921 gacggcagtg gctgctccat cagtacggca agtgcctcga tgatgacaga cgccgtcatc
    10981 ggaaaatcaa tagaagaagc agaacattta actgtagact ttctacagct tgtccaagga
    11041 aaagaagtca aagatcccga ccaattaggc gatgctgcta tgcttggtgg tgtagctaaa
    11101 tttcccgctc ggatcaaatg tgcgacactt gcctggaaag cactaggaaa agcaatggaa
    11161 aacgatggta ccgcagcttt ccatcattac cacaaggaag aggagtgaga acatgggcgt
    11221 accagaatta gaagaatata aattcgggtt tcacgatgat gtcgaaccgg ttttcagtac
    11281 aggagaaggc ttgacagaag aagtgatccg tgagatgtca agaatcaaag gcgaaccaga
    11341 atggatgctt gaattccgtc tgaaatctct agaaacattt aacaaaatgc caatgcaaac
    11401 atggggcccc gacctttcag acatcgattt cgatgccatc aaatattacc aaaaaccaag
    11461 tgacaaaccc gctcgtgact gggaagacgt accagaaaaa atcaaagata catttgaaaa
    11521 gattggtata ccagaagctg aacgagctta tctagccggt gcttccgcac aatatgaatc
    11581 agaagtcgtg taccataata tgaaagatga attcgaaaag ttaggaatcg tctttactga
    11641 cactgactct gctttgaaag aataccctga attattcaaa gagtactttt caaaacttgt
    11701 accgccaacc gacaacaaat tagcagcgct gaattcagcc gtatggtcag gtgggacctt
    11761 tatttacgtg ccaaaaggcg tcaaagtcga tgttccatta caaacgtact tccggatcaa
    11821 tgcggaaaac acggggcaat tcgaacgtac gctgatcatt gttgacgaag gagcaagcat
    11881 ccactatgtc gaaggttgta cggcacctac ttattcaagt aacagcctgc atgccgccat
    11941 cgtagaaatc tttacaagaa aagatgcgta ttgccgttac acaacgatcc aaaactggtc
    12001 agacaatgtg tacaacttag taaccaaacg agcaaaagca tacgaaggcg caaccgttga
    12061 atggatcgac ggaaacctag gtgcaaaaac aacgatgaaa tacccaagtg tttacttaga
    12121 tggaaaaggt gcacgaggca ccatgctctc catcgccttt gcaggagcaa accaaatcca
    12181 agatacgggt gcaaaaatga tccacaatgc accaaataca tctagctcta tcgtctctaa
    12241 atcaatttca aaagacggcg gagaagtaaa ctatcgagga caagtaacct ttgccaaaaa
    12301 cagtgcgggt tcgatctctc atatcgaatg tgacacgatc atcatggacg aatggtcgaa
    12361 atccgatacg atcccattca atgagatcca caacagccaa gtctctttag aacacgaagc
    12421 caaagtctca aaaatctcag aagaacaact ctactatctg atgagccgag gcctgaccga
    12481 atctgaagca actgaaatga tcgtcatggg ctttgttgaa ccattcacca aagaacttcc
    12541 aatggaatat gcagtcgaac tcaatcgatt gatcagttat gagatggaag ggtctgtagg
    12601 ttaataacta tttcattgct cgaaacgttg atattaaagc gtttcgagcg tttttttatt
    12661 tgtattttaa tggttggcta cgtttttggc tacgtttgga attattcgcc cataaatttt
    12721 gcaaatcggt caccagtttt cttaacagat tgtggtgtga catgagcata gatattcatg
    12781 gtagttttaa tatctttatg acctaatcgt tcctgtactt cttttatcga cgcaccactt
    12841 tcaaacaata agctacagtg ggtatgccta aatccatgtg gagtaatttg aggctccatc
    12901 ggtgtctttt tgtaaatcca gtctaaccaa tcgtttacta cttgggggta gtacaacttg
    12961 tttgtgtttg tagtgaaaag aaactgtttt ggtgaattcg tgttatagcc atataagatc
    13021 attattttca tttgttcttg ttgccaaata cgcagttgtt taagtgtaaa atcatcaagc
    13081 tgaatcgttc ttgatgaatt tttagtttta ggtacttgta gaactacttg attaaactcg
    13141 tcttgagcga tagttttacc aattgttatt gttttattga aatagtctat atcttcccat
    13201 tgaagcgcca atgcttcgct tttacgcatt cctgtataag ctaataaacg gaaaaaagtg
    13261 tacagtttaa ctgaattatt ttctttagta ttctgtaaaa acagttgtaa ttgatctttc
    13321 gtgtaaaact tcaagggttg ttcttcttca atttttcttg gaagcaatgt tttagacata
    13381 ggattatcct tacagacttc cattgctact ccaaatttaa atatttgagc agttgttttt
    13441 ctcaagaaac catattgttt taatgttttg tgccattcat tcacctgttt ttggcaatag
    13501 ctaacactta ttttatccaa tcgtaattcc ccaaaagcag gtaatatatg gtttttgcaa
    13561 aaacgttgag caacggcaac agaagacggt tttactcttg ttctgtagtt atcaatccat
    13621 aattcataca actcttgaaa agttgtaaca ttgattttaa actcttgttt ttctttaaag
    13681 tctacaagta gtctattaag tgctgtttgc gcctcagctt ttgatttgaa tcttctacgc
    13741 tttgtacgta tatcttttcc agtcttggga tctttcccta aataagtttc aaatccccaa
    13801 tatttttcgc cattttgtaa tttataacta aaaaatgttg ccatttgatt ctctccttac
    13861 ttcattattg caggtagaga agttatttga agaatcaatt atttttaaat ttatcgtgat
    13921 tatcagttaa aaattttgcg attatactat ttttctcata tgggaaattg tattttttac
    13981 taagatctga aataaatttt tctgtttcaa attggttttt agtaatttta taaaagaaat
    14041 cctcgacaga tgaatacttt gaaatatctt tataggctaa gtccatttcg tctaatagct
    14101 gttttaaaga atcaatcatt ctttcttttt caccgtattt gaaatcacca tttcttatct
    14161 tgtcttgaag tttactgttg gctcttttga aaaatagctc tttagagata gagtgtcttt
    14221 ggttagcgta ctcttcaatc agaggattga tattattagc aagtatctca tttagataaa
    14281 tttcaaaatc ttttgagtaa tattttgtaa atatattttt tattatagga ttcaataact
    14341 catagtcttt atctagcgaa aacgtatcac tatatctttc ttgaatgtct ttaaagactt
    14401 tgtgaggtat ttctgg
//
LOCUS       DBBGSP010000070        14130 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000070 DBBGSP010000000
VERSION     DBBGSP010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.070"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..244)
                     /locus_tag="ACIZE9_002544"
     CDS             complement(<1..244)
                     /locus_tag="ACIZE9_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGC6094362.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELI"
     gene            complement(237..1829)
                     /locus_tag="ACIZE9_002545"
     CDS             complement(237..1829)
                     /locus_tag="ACIZE9_002545"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HGC6094363.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(2339..3064)
                     /locus_tag="ACIZE9_002546"
     CDS             complement(2339..3064)
                     /locus_tag="ACIZE9_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094364.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(3218..3544)
                     /locus_tag="ACIZE9_002547"
     CDS             complement(3218..3544)
                     /locus_tag="ACIZE9_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094365.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(3581..3946)
                     /locus_tag="ACIZE9_002548"
     CDS             complement(3581..3946)
                     /locus_tag="ACIZE9_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HGC6094366.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(3983..4198)
                     /locus_tag="ACIZE9_002549"
     CDS             complement(3983..4198)
                     /locus_tag="ACIZE9_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6094367.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            4327..4662
                     /locus_tag="ACIZE9_002550"
     CDS             4327..4662
                     /locus_tag="ACIZE9_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6094368.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(4738..6735)
                     /locus_tag="ACIZE9_002551"
     CDS             complement(4738..6735)
                     /locus_tag="ACIZE9_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094369.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(6833..7108)
                     /locus_tag="ACIZE9_002552"
     CDS             complement(6833..7108)
                     /locus_tag="ACIZE9_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094370.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            7340..8074
                     /locus_tag="ACIZE9_002553"
     CDS             7340..8074
                     /locus_tag="ACIZE9_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6094371.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            8113..9255
                     /locus_tag="ACIZE9_002554"
     CDS             8113..9255
                     /locus_tag="ACIZE9_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6094372.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(9883..10368)
                     /locus_tag="ACIZE9_002555"
     CDS             complement(9883..10368)
                     /locus_tag="ACIZE9_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HGC6094373.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(10370..11041)
                     /locus_tag="ACIZE9_002556"
     CDS             complement(10370..11041)
                     /locus_tag="ACIZE9_002556"
                     /inference="COORDINATES: protein motif:HMM:NF037286.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094374.1"
                     /translation="MSRFSINVVEVDDYSEITDILKSIRKKYLRKTIFISGSAVDYTP
                     FTSESKGLKFVEKLAYRLSESGYRIVSGYGLGIGNSIVSGVLKQRRNLRKNNIQDVLS
                     LRPLPLDMPHEWRRYRENIIAESGISIFVFGNKLESGEIVTADGMIEEFELSVQNENI
                     VVPIGFTKGASKVLFDKIQENFSDYFDDSLKSKFQALEKLDTEGEVDKKVEQIVSLIN
                     SIQED"
     gene            complement(11304..12497)
                     /locus_tag="ACIZE9_002557"
     CDS             complement(11304..12497)
                     /locus_tag="ACIZE9_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6094375.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(12581..12781)
                     /locus_tag="ACIZE9_002558"
     CDS             complement(12581..12781)
                     /locus_tag="ACIZE9_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HGC6094376.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            complement(13205..13438)
                     /locus_tag="ACIZE9_002559"
     CDS             complement(13205..13438)
                     /locus_tag="ACIZE9_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094377.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(13445..13876)
                     /locus_tag="ACIZE9_002560"
     CDS             complement(13445..13876)
                     /locus_tag="ACIZE9_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGC6094378.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         4295 a         2895 c         2270 g         4670 t
ORIGIN      
        1 tgattaattc attatatttt ttttcagtaa ttttatatct tgtttcgtaa ttatcataaa
       61 tagcattttg ttgttcatag acaacaaaat tgctattaga tacaaagaat tctttcttta
      121 aggcactccc aaatggtccc ctccttactc catctttttt atcaagtaag cattcaaact
      181 tacgctgttc ccaagcttcc gtaaatcctg ggaaacgaat ttctggttgt atatcattac
      241 tcatgtttga acacctccag cgcaccttgt aaccacgctt cattttcagg tgttgtttgc
      301 agggaagaga tagcttctaa aagttctttt tctagcactt gctgttcttg tcgtatcttc
      361 ttgatgtcat ttccgacatg aaccatatca attggttctt cttcttcaaa cgtatctaca
      421 tagcgtggaa tatttaagtt atagtcattt tctttgattt catcaaagtt tgccaaatga
      481 gcgtatttct cgacatcttt tctttcagca taggtttcga ggattttttg aatgttttct
      541 tccgataatt tattctgatt ttttcctttg acaaattctc gactagcgtc aatgaataat
      601 acgtctcgag tttggcggtt ctttttcaat acaatcaccg tcgttggaat cgatgtcccg
      661 aagaacaagt tcgcaggcat accgatcaca gcataaatac tgccgtcttc tagtaatttt
      721 tgacgaatga ccccttctgc agcgccacgg aataaaactc cgtgtggcaa gacgatggcc
      781 atagtccctg tttccttcaa atgatagaaa ccatgaagaa gaaacgcaaa atctgctttg
      841 gattttggcg ctaattttcc ataacgatta aaccgagaat cgtctaagaa ggtcgtatct
      901 gctgaccaat tagccgaata aggtgggttc attactactg catcaaatgt gtaaggttca
      961 tctgttggcc aatccttatt caacgtatcc ccattgcgga gattcatttc ttcggcatct
     1021 accccatgta aaatcaagtt catttttgct agattgtatg tcgttgtatt taattcttgc
     1081 ccatgatatt taacgttatc tgggtgagtt aagtagttac gcacatttaa catcaatgaa
     1141 cctgaaccca tggttggatc aaaaacacta aagaatcgtc gttctttttg atccaacgtc
     1201 acgatttgtg ccatcatatc agaaaccata tgaggcgtgt aaaattctcc ggctttcttc
     1261 cctgcttctg aagcaaattg actgatcaga aattcataag catccccgat cacgtcccca
     1321 tcgtgaccta aaacttccac gtcattcaat ttcttaatga cttcggtaat cgtcacattt
     1381 cgttgttgct catctgttcc tagttttttt gattggagat ccacatcatc aaataaccca
     1441 ttaaattgat tgtaggtaga tgccaattgc acaaaggctt tgtttagatc attcaattgg
     1501 aacgttgctt gttttgcttg atccgctaag acgttgaaaa gatactctgg cgaaatcgca
     1561 taccccaaaa tatcaacgat tgttgcaatc agatcttctt ttgattcttc atctgaaagt
     1621 aattcgcgat acaacatcgt ttgtttgctt accgtatcat attcctctaa ggattcatct
     1681 gctaaaagaa ccacttgttc caacaaacgg tcggataaat atttatagaa aatcagtccc
     1741 aataaataat ttttatattc tgacgcatcc attttgctac ggagattatc tgccgcacta
     1801 aataattttt gatttaattc tgcacccaaa aagatacact cctatctctt atttaaagtt
     1861 gctatatacc ctcttatttt agcatactcc cttttagaaa aagcaaaaaa aaaaagaaag
     1921 aaacttattc ttgctaataa actacgcgaa aggagtctaa cgttgtttga tataacttag
     1981 actgatcgtt aacttatttt ttatatttct acatagttat ctttagaacc atttcagata
     2041 catatgaaac aattacatat gattttttca taaaaaaaca gtactgtcta gtagtataaa
     2101 atatacaaat ttcttaaaaa ttttttcact aaaatcacta cctgaaacag tctaaaacac
     2161 ttatatatca acgtttaatg aaactatctc cgtttcattt cagatacaaa taaatatagt
     2221 cgggctccaa atccgaaaaa aaataccccc agtagcttat cctaagctac tggagatgta
     2281 taagtacggt catataacaa cggggtaggg taaataaatg aaaaagatgg aagaatcatt
     2341 attcaataac ttttttaaat acttcgttgt aatcagttac ctgtccgttc ttaaatacca
     2401 cagaataatc ttttttccca ttttcaagta accgaagtgg aatatcttta ccaactttct
     2461 ctgtcactgc attactgata cctgttagat tagctaataa atctgataaa gattgagcat
     2521 ctgtagaaat ctctgtatca gtatttatcg tgattccttt atcttcattt acaagtttcc
     2581 aagtaggtgg tatagctgtg tatgtttcta caaatgaatt aagtttttca ttaagtgact
     2641 tctcttttat atttccatct aaaaactctg tatatatggc ttgagctata ctaaaacaaa
     2701 gctggccttg ttctaataat tttacatcat tagttagtaa agctgtgttc acgttatcaa
     2761 tcgcttcaag aagagtatct ttggtgtccc taacagcttt aggtgtgcct tctggaattt
     2821 ccctacttga tacctcgtcc attttatctt ccataaaccc cttaaaatca tatctttctc
     2881 ccaaatccat agaagttttt gagaaagctt tcatttctga gtctatttct tcaataatat
     2941 ttaacatgtc tgatacatat tgtttaggct gattcgtttt taatctatat gtggtaaata
     3001 tctcaattcc tccaattatc aataaaattg ccaaacaaat ccataataat tttttctttt
     3061 tcatttttcc tcctatacac tgctgttata acagtgacta atgtaaagat tttcccagca
     3121 atcatcagac tattatttac agggaatcaa aaaaactcct tagtaagctt acacctttag
     3181 gagttcctgt ttgaacggta tgcataatac atttaaatca atttaacatt aacacctcag
     3241 tatatggtat ctctacatat acacggtctt tttttggata gtactcgaca tttatattga
     3301 tagcacttcc attgtctaac gtagctttag cccggtacgt gttatcacca ttatcatgag
     3361 tgatcgtcac atcatcacat gtccgattta agttatactg ttcttgtaaa atctgagtta
     3421 ccaatggtac agatgacttc tctagtccag atgaacccgt cattcttgaa aaaattatac
     3481 ctataatagc caatacaacg atacctataa tgacaaactt cttattcata tttactttat
     3541 tcaacttttt atctcctatc tccaaaatga ttttctctca tcagtaactc attgacatcc
     3601 ccaatagtac accaaagatg gctccagcta cccctgctat catcaaaatc gtacccattt
     3661 gttcatcttt ctctcgatat aagtaaccca taataacagc aacagcacca aataccacag
     3721 gaataaatgc taatgatact accatagaaa tccaaccaat aatcaaatac agcttccctg
     3781 tctcttgtcc atgtacgatt tgttccttca tttcattaat tgtctgctca gtacttttct
     3841 ttactgtgtc tgttccggtt gtctcatctg tttcttgtaa tgctccgcaa aactggcaat
     3901 acttactttc atttgttatt tctttaccac attttctaca atacatgtct tctcctccta
     3961 aaatcattca attgcttatt agctaactgt ttactttatt aaatacatca gaaaacagct
     4021 catttattgg tacacttaat atctcagaaa gcattttcat ttgatagggt ttaggaatcg
     4081 ttctccctgt ttgccacgaa cttacacatt gctgtgtaac attcattttt ttggctaact
     4141 cagtttggga aagtcctttt tcttttctgt atcggctgag attacttact tttttcatga
     4201 ttctcccctc ctgttttatt atatacaaca atatgatgta tttcaactca taaaatatat
     4261 aaatacttca aatgtcatta caaatacaac aacttgttgt actctactga gaaggggggt
     4321 gtattaatga aacagaagca atatgcaaag gtcattagag aaaagcgaaa agcactcggg
     4381 tggacacaaa aagaattagc taaaaaaatc ttctctacac aacaggcagt agcaagatgg
     4441 gaaaattctg taacagaacc taacctcgat agcttaacag ctctttctag agccctagga
     4501 acccctgtaa gccattttct agacaatgtt gacatagatt atgaggaaga gtttttggct
     4561 ctctatcgct ctcttagtac tgaagatgca attcgaacaa ttgactatat gaagctatta
     4621 aaaaggcaag aaaatgaacg caatcagcta ttgaaagatt gaaaaataaa taacccaccg
     4681 aactttaacg gtgggtgtat tgagatgaaa taagattaag agctatggat aacctgtcta
     4741 gtttaatata attgggtctc ttctattcct tactctccgt ccatcatctc ttgttacact
     4801 tgtaaattga taaataggaa ctaattcaac tcctgataat atcaattctt ttattacttc
     4861 atctatccct gcccctttcg ctagatatac taaaaaacta ctgcttgctt tcacattgta
     4921 tagtttctta atatccttag aagctcgttc aagagtgaat ccttgtttaa caaagtagcc
     4981 tctgttttct attaaagcat ttttcacgct gttatccctg acatttcgta ggcgttcaca
     5041 aacagtgtta ataagttctt tttctgtcat tagatatgtc ccttgccacg ataagccctg
     5101 taaaacttca tgtgcttcat ctaaaatcaa ttgtttttcc ttgctaagtt ctgatcggga
     5161 attttgagga aatactcttt tagcctcttt ttcgttaaaa catatcttaa cccattcata
     5221 agaaaaatat tgatatgtaa aatgaaattt ttccagaagt ggaaggatat cttcattcaa
     5281 tttttgaatc acagaagttg cattaaaaac gtctaatcga tagacattgc ttctcttatg
     5341 tttaaagttt cctaacgctt tctcttcctt taacctattt aggtattcga gcatcttcaa
     5401 aggaacatct tcatcatcta atttttttat caatcctata aaagtcataa gtgatagtaa
     5461 cttattacat ttatctatgt cataagtttt accatagtaa gaactcattt ttttagctaa
     5521 ttgttccccc gacaaaatac aagtcacact ttccttacta tcatcaaaaa aattaacatc
     5581 agaaagcaag acatcataga cacgtcgcat ttcctctaga taattcctta ttgtcctgaa
     5641 aagtttgtct ttcattgatt caagagtgtc aaaaagtact tttgattcct ctttcaattt
     5701 tcgaaaatgt gtaggataca agtctaggtt ctctaatagc caattaaatg tttctacccg
     5761 actgtctttc tttaaaatta gcatcacaac tccaataaaa ttttcactga tatcacaatt
     5821 actggaatga caataaaaaa tggaatgccc agttttactg gtaaaaatac tagcagaggg
     5881 attatgatcg ttgtgaaaca gacatcttaa gtttttactt gacttaagta atttattcat
     5941 atcaatggtt aacaatcttt cataaatctc attaaaagac atgtcggagg aatcaaacag
     6001 gcagtcttta aaccactgtt tcatttcttc tttgtcgtca ttttttatca acttaacaaa
     6061 atcggtttca ttgactagtt catactctct ccctgaatca ctttgacaat ttttagaaca
     6121 tgtcatggta aaatcaatcg gaagctcagt aatatctaac atgttgtctt cattaattat
     6181 tatcactgca tctgacttat atcctccaaa aaacattcta ttcgaagcat ttacattgtc
     6241 atcacacccg gggatgttct ttttcaagta ttcgtaaaca gcaaccattt taccatagtc
     6301 agtaattgct tcttttaata gaaagacaat cttgtatttt tctagatttt cagagtaccg
     6361 aatacttttt tgtatcgcaa acgcagaatt atgaactaaa ttgatagata aaaccttttc
     6421 tatgcttaag tatctactat catctttact caaatctact accttcccct tctcatcttt
     6481 aacagtgtta tcgacatcca gaataattac tctggtttcc acaaaactct ccttgtcatt
     6541 gcctttattc tttgtcttgc ttggaataaa tgattgtgat gaatttagta tctctacaaa
     6601 ctcatctctt gtaacttctc tatagttatc taaacaccta tctcttacat cagttttttc
     6661 tttttttgta actggcttct ctaataattt ttctttatct acataaattg gaatattaat
     6721 cattgatgtt tccatttgtg tttcctcctt ataaaattct gttaaagact aaaacataca
     6781 gataataaaa acaaactctt tattactata tgttttagtc ttatttgttt actcaacctt
     6841 tataccgttc catgaaacta tcaatatcag attttttaaa tctaatgacc gtatcaattt
     6901 ttataacagg taacccgtat tgagaaacat attttctaat cgttcctact gatacaccta
     6961 gatattcact tgcctgctga tagtccatat actctagagt gactccagaa ataatgtctt
     7021 ctagcatagg ctttagcact gtaattatct ctttcacttg ttgttcaact tgtatagaaa
     7081 caatgctatc aatgatttgt agagacatat ttccccctcc tttcgtgatt gcttgaacaa
     7141 attttctaag aattatcttc gtattttttg ctcaaaataa aagtattttg ttattaaccg
     7201 attaatcaaa caaaaaatga ttaccagttc atcgacatac acataatacc tcgataaaaa
     7261 aggggtgtca atagttttgt aaaatttatt tacaacaccc cttttttgag gtatactaat
     7321 tttaggaggt gtggtcaata tgataaaacg tccaccaata aattatttag aacgaaaaaa
     7381 gatactcgga acaaaaataa aagctataag aaagagtaaa aaattaacac aaccagcatt
     7441 tggtcttatg attaacaacg gtcaattaat tgacaaaaag actatctacg aatgggagaa
     7501 gggaacctat ttaccaatac cagagcgatt atcccgaatt gctgatttgg gaaatatgag
     7561 tatagaggag ttagtttgtg gcaatgtaga agaatatatt ttgggaatta ttctttatag
     7621 agatagcatt gtactagatg gtataacatt tccagataaa aacctgttcc agcatcttcg
     7681 tcaacagttc ccaccagtac actctaattt agatacatgg ctggatagat attccaaatt
     7741 agaaccagag atgcaagaat ttattgctaa caagacttgt aataaagtta aaaatgaaaa
     7801 aattagtctt ttcaatatct taaaaataga agaattattc atcaatgcta ttgtagaaga
     7861 atttgacaat aacattcttt tcctcactag cagtatagaa gaactactag aaagaatggt
     7921 agatgaatgg ctacctattc aattgaaaga catgtcttat cccgaagaag ctgtgagaga
     7981 aattactgat aatataaaca agctagaaca aacgatttca tcaattggga aaaaatacac
     8041 taagaaaaaa atgaagggag gtgataccat ctagtggtaa gtactccttg taaactaaga
     8101 ggagatgatt tcatggcaaa aatatcaaag tacaaaaaga aaaacggtca agtggcgtgg
     8161 atgtataaag gacacattgc caccgatcca cgaactggtg aaaaaataaa tactacgaga
     8221 agaggtttta gtagcaaaca agaagctcaa aaagattatg acgagtacag acatcaaata
     8281 ttatacggtg ttaaaaagaa agcacctgat atgacatttg aagacctgta taatgaatgg
     8341 ataactcatc agcgtaccag tgttaaagct tcaacaatcg caatctcagt aagatacgca
     8401 aataatcaaa tacttccagc atttggtaag cttaaactat cgaatatctc tgtcccatat
     8461 tgtcaaaaag tggtagatga atggcacagt aaatatgaaa gttacgatta tatgagaaaa
     8521 cagactgcac aaattttacg ctacggggtt gcaatgcaat atattgacaa taatcctatg
     8581 gaaaaaacac ttcttccacg aaaaaaagag tatgagaaaa atcgtaaatt ttactcaaaa
     8641 gaggagctta ataatttact ggatgctttt aaagattttg gtaacatgaa acaatacgcc
     8701 ttcttcagat tattggcata cacaggtatg agaaagagtg aagtactcgc tttacagtgg
     8761 aaagacatag acacgtttaa taaagaacta catgtcaata aaactcttgc tgtagatgaa
     8821 tttggtaaag ttataattca atctccgaaa acaagagctt ctagacgagt tatctcttta
     8881 gatactgaga ctctttctat cctcaacaac tggaaattac agcaaaaaga agagtattta
     8941 aaacttggat acaatactag ctctaaagag caacatgttt ttacaacagt taaaaacact
     9001 ctatacattc caaacactgt taatgattgg ttaagatata ttttgaaaaa atataacttg
     9061 cctcgtatta cacctcatgg gtttagacat acacatgcta gtttattatt agaagcagga
     9121 gaatctgtca aggtagttca acaacgatta gggcatgaaa atagtaaagt gacattagac
     9181 atctatgcac atattacaaa taatgcacct aagaaaacag gtcaagactt tgctgatatg
     9241 atggctcatc agtaaaagag ctggtcaaaa tctggtcatt tctagtatac aggcaaaaca
     9301 aaaaagctag aacccttata tatcaagggt tctagctcct ataacaggtt tacccaacac
     9361 tgccttccaa tgactctttt gggaatcaga ggaaagaatc aggctttata gagatatttc
     9421 atctaacaaa ttactttaga ctgacagtat atatcagcag gtactgtcat cgggaacgta
     9481 gccaatatcg tatccaaaac agcaggtaga gaagctattt gaggattcaa gttattctat
     9541 ttcaaccatg aagttaagtt cattaaaaat aaagatagtt ggtatttcaa taatttttgt
     9601 atagagttaa tcactttatt gatgctaatt catcttgatt ggtattataa tcgtattcaa
     9661 gttgcgtggc gtgcttttgc tagaaaatat ataactgttc tttataaaga aatataagga
     9721 ttaaacattt tttatcatag agttttactt atctatagaa ttatgtctgt tcctaattca
     9781 gtttgatgaa ttaactgata aaaaaatatc tactatttaa agatacaggg ataagtaagt
     9841 aaaaaaataa catgtcatta gatagtagac agttccaact ctttatttac cttttttgta
     9901 tgctgcactg tcaatccaag ttcctaaatt gttgtatcca tcatcactta tataatcata
     9961 ttggccatca ataatttcgt caaaccacaa atattctcca tctggttttt gcccaattat
    10021 tttaattact gattgactag tagttgtcat ctggttaaaa tcttttattt tacctatatt
    10081 aacggccaaa atagcatttc ctcgcttata actctcctgg atttcatatt taacatattc
    10141 tcgatcaaga gtttctttac ctatcagcac cacagtcact gatgttccaa ttaattgatt
    10201 atctatccag ttttttatag caatatctcc attacgttta actttctcaa attcagcctt
    10261 atctacaaaa ccagcttcct ttgttcctcg caaagtccag ctgtttctaa ctaccattgc
    10321 tcttgttaca tctgcataat ggaaactaaa aaaaaccctt ctcaccatat taatcctcct
    10381 gaatactatt tattaaactg acaatttgtt caactttttt atctacttct ccttcagtat
    10441 ctaatttttc tagcgcttga aatttacttt ttaaggaatc atcaaaataa tcactgaaat
    10501 tctcttgaat cttatcaaac aaaaccttac ttgcaccttt ggtaaatcca atcggaacta
    10561 ctatattttc attttgaaca gataattcaa attcttcaat cattccatct gctgtaacta
    10621 tttcacctga ttcaagtttg tttccaaaaa caaaaatact aatcccagac tctgcaataa
    10681 tgttttctcg atatcttctc cactcatgag gcatatcaag gggaagtggt cttaaagaaa
    10741 gtacgtcttg tatgttattt tttcttaaat ttcttctctg ctttagaact cctgaaacaa
    10801 tactattacc aattccaagt ccgtaacctg atactattct ataaccggat tcagaaagcc
    10861 tatatgctaa tttctcgaca aattttaatc ctttcgattc agatgtaaat ggagtataat
    10921 caacagcact tcccgaaata aaaatagttt ttctcaaata cttttttcta atacttttca
    10981 aaatatcagt aatctcagaa taatcatcta cttcaacaac gtttatcgaa aatctggaca
    11041 aatcattgat ttgtagtctt ctttttgtca gttcataatt atatctctct tgatcaaaaa
    11101 aatcctcaga atcgacaaaa ttttccttta aaattatatg ggattttaga ttatcttttt
    11161 agaagttctt gaatgtcggt atagcccgtg tttccgggct tttccggcat ttttgatatt
    11221 gttagatact tacaaatgtt cttattacct ctcaccattt ccccctcaaa agtagtaaat
    11281 ggagtagtaa aaccggcctt gtgtcaggct gccagccgtt ccatttctgc ccttgcggaa
    11341 tcgaatgtgg cgtgtgcata atagttcagc gtcatggtga tattggaatg tcccataatg
    11401 tactgcaagg ctttggggtt cattcccgca ttggctaacc gggtgcagaa tgtatgacgc
    11461 atagcatggg gcgtcgtcgt tttcggcaac gcttcttcat ggctcttgtt gtacttcttc
    11521 acaagcctgc caaacatccc gccataatct accgccgtca tgggatagcc gttctgtttg
    11581 agaaacagga aattggcata cccgtcaata atgaacggct ttgcaccttt gcggtttttt
    11641 atcactcgct ggaacgcctg atacacttcc tcattcatgg ggatttttct gacgccgctt
    11701 tgggtcttgg gttcgtcaat atagtaaccg acgccggtat ttctcaaaag ctggtggctc
    11761 acgatgatta cccggttttc aaaatccaaa tctttgtccg tcagtccgca cagttccgaa
    11821 atgcgaagcc ctgtccccag cagaataacg attgcgtcat aatgcttttg gtaaacctta
    11881 tcaccttgaa taaaggacag aaaactttct tcctgtgctg gtgtaagagg cacctttggt
    11941 tccgtatcgt cgtccagaac gtcactaagc tggaagtcaa acgggttttt tcggatgcaa
    12001 tcgtcctgta tggcggtgta aaaagccgct ttcagggaac gcttgtcgtt attgatggtc
    12061 ttataagaaa ggcccttttc tttcatccga agcgcccatt cctttgcgtc ggacagcttc
    12121 acactgtcaa tcgggcagct ccccagccga tcttgttcca gaatacgcat cagccgttcc
    12181 cggcccagtt tggtgttgtg cttcacattg ccccggtgcc tgatctgctt ggcgtagagc
    12241 tggcagacgg tcattttctt gccgatggtg tctatcccgt cgtcaaggtc tttctggatt
    12301 tctttctcct tttcccggag tgaaatatcc tcccgtttac ctgccggggt cttatccgta
    12361 ggcactaact tccatgagta aacaaactgc ggttttccaa aggtatcaac atatttgtaa
    12421 gcatatcgtc cgtcttttct ctggctctct ccagaccgca aaacgcgatt tttgctgtct
    12481 cgtctttttt ctgacatctc gtcatgctcc tttccatgac ggaaagagcc gcatatatgc
    12541 ttataaatta ttataacata tctgcggccc tttttcacta ttagattgtg tccaaagtgt
    12601 caattatttt ctcaaactgc ttgcgtttga tctggatgcg gttgccattc ataatgaccc
    12661 agccagaggc cggattttcc tcggccagct tacgcaattt gttttctccg atacggaaat
    12721 atttagacgc ttcctcaatc gtcagcgtgt atttttccca aataggcaca tcatggttca
    12781 taatgcagcc ccctttcaca aattcaaagg tttgtgtgat ttaggggcat agacggacgg
    12841 ctgctggcac agctccacgg gactttcacc cccgcgtggt tctcacgcgg ccctacccat
    12901 tgcctgcgac gcttttaacg ctcggactgt ggctataagg gagtatcata gtcctgcctg
    12961 tacgtcgtcg cccgcaagcc gccacgctca cattgcggcg tggtgttcct cgctccgctt
    13021 ttcccgtagg gaaaagtatc atggcgcacc agccgtccgg ctcggcacag acagaatgtg
    13081 tccgtatgcc ctatgatgcg ccgccgttat cttgcgggca tatttatcaa ggtgcgatca
    13141 ggccaccggg aaaacaccga aacggggaaa gggtaagccg tttcatgctg ccggggccgg
    13201 ttcgtcagtt cgtgacgata gcgtggatga gcttgatttc cagacggcgc ttcatggcct
    13261 cgtccagaca cacatgcgga tagccgtttt cgtcatagag cgtccgggta cacagcttgt
    13321 tcatgtaacc gctgtaatac tgcaaaacgc gctctacggc tccggcatcc ccagcgcggg
    13381 cggcctcgat caccgaaagg ggcaaaagct caatgccctt gtagttcggg ttcttcatcc
    13441 gcgtctaacc tcccttcggc atcaacgcct ttagctgttt ccgcagctcc gataaggtat
    13501 ttgtcctgtg ccgctgaacg gcactccggg acattcccac aaggccgccg atctcaccat
    13561 ctgccatatc cagaacacag tgcaggatta aaatactctg ctccatgctg ggcagcgcgg
    13621 caaaggcttc ggcaacaagc tcattgttga tatgtaggtc atagccatgc gacgaaaacg
    13681 taaagctgtc gctggggtag tgatctactg tacagagctt gtccaaatct gcctgtgaca
    13741 aagagcttag tgacacttca cggtcacggc ggcgcttcat ttcagccaag tagcttttgg
    13801 cctcgttacg cagtaccgtc ttgcaaaaag catcgaacat gcaccgcgct tcatagtcgc
    13861 gggggatagc atccatcttc tcaccccctt tctgtggggg acttaggtgg ttctctccct
    13921 ttccgctaac aagactttga caaggccgcc agctacccgc taaatacctc ctttttgaaa
    13981 atttctcaaa aaattttttt ggggacagcc gggccgcaaa agacgacaaa aatcgcccgg
    14041 caggtcgcaa acctaccggg cgagaaaatg ctttgctatg ctgctgattt acatggtata
    14101 gtacatactc ataaccggaa tagccctgtg
//
LOCUS       DBBGSP010000071        14129 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000071 DBBGSP010000000
VERSION     DBBGSP010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.071"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(41..3694)
                     /gene="rpoC"
                     /locus_tag="ACIZE9_002561"
     CDS             complement(41..3694)
                     /gene="rpoC"
                     /locus_tag="ACIZE9_002561"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGC6094379.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(3773..7390)
                     /gene="rpoB"
                     /locus_tag="ACIZE9_002562"
     CDS             complement(3773..7390)
                     /gene="rpoB"
                     /locus_tag="ACIZE9_002562"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGC6094380.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8118..9086
                     /locus_tag="ACIZE9_002563"
     CDS             8118..9086
                     /locus_tag="ACIZE9_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6094381.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9104..10009
                     /locus_tag="ACIZE9_002564"
     CDS             9104..10009
                     /locus_tag="ACIZE9_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6094382.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            10006..10812
                     /locus_tag="ACIZE9_002565"
     CDS             10006..10812
                     /locus_tag="ACIZE9_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6094383.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10969..11937
                     /locus_tag="ACIZE9_002566"
     CDS             10969..11937
                     /locus_tag="ACIZE9_002566"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HGC6094384.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12254..12778)
                     /locus_tag="ACIZE9_002567"
     CDS             complement(12254..12778)
                     /locus_tag="ACIZE9_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HGC6094385.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13065..>14129
                     /gene="scm"
                     /locus_tag="ACIZE9_002568"
     CDS             13065..>14129
                     /gene="scm"
                     /locus_tag="ACIZE9_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HGC6094386.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT         3996 a         3046 c         2791 g         4296 t
ORIGIN      
        1 gttgtgacaa taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca
       61 ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg
      121 ctacaccgac ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga
      181 tgatcttacc tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga
      241 tcgcagcatc cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat
      301 ttgtttctaa tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc
      361 ctcctgagac tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac
      421 ctggtaagat atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa
      481 ccattacttc gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta
      541 cttcacgaag caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg
      601 gatcgattga tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt
      661 tcatacgtgc tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta
      721 cttctttggt acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg
      781 tgatcactgc ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac
      841 cttgagtgat atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag
      901 taccaggttc accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt
      961 cagagccagt tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac
     1021 atgtgaagac agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga
     1081 tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta
     1141 cttctttacg ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc
     1201 cctcgcggat ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga
     1261 ttacatcttg ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca
     1321 aggctgtatc ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg
     1381 atagtccttc acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg
     1441 ccatcaaacc acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag
     1501 aatcagacat catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga
     1561 tgctgtcttt tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga
     1621 tcagaccacg acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga
     1681 tttcttgttt ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg
     1741 tcgaatgttt gtaccctaag tctttcatac ggtcaagcat cttagaagtt tctgttactt
     1801 tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata
     1861 ctaattcttg ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt
     1921 ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag
     1981 gcatgatctc gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc
     2041 attcagtaaa tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat
     2101 gaacatatcc gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt
     2161 cgccttcgcg tccttcttct tccattgtca agtagtagtt acctagaacc atatcttggg
     2221 aaggagtaac aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca
     2281 acatacgtgc ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc
     2341 catcgaaatc ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt
     2401 gtactaaaac tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca
     2461 gcaatactgg gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac
     2521 gttcgatttt acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac
     2581 gcatcacgaa tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca
     2641 tcttcaagaa aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta
     2701 gcaagttttg acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg
     2761 ggcggttacc tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta
     2821 ctgcttcttg cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta
     2881 acaaacgttt caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac
     2941 ttgttgcaaa acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag
     3001 ggataacgtc cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa
     3061 tatccaaacg gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt
     3121 tcaattcggc tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg
     3181 cacccatagc agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt
     3241 ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag
     3301 caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg
     3361 aaggaatccc tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca
     3421 tgcgttcacg gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc
     3481 ctttataacg gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa
     3541 aaatccgctc acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct
     3601 caggtttttt tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta
     3661 tttgcatact ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat
     3721 ggcaaaccgc aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta
     3781 aattatcttc tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt
     3841 cagcagcttt cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat
     3901 caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt
     3961 cgatatccaa gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga
     4021 atgattccgg tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt
     4081 tcacacgtcc gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg
     4141 caccgtaagc ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag
     4201 ctttacctcc caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca
     4261 atttgtcatc gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc
     4321 catcaaatgg ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac
     4381 cggcttcacg aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg
     4441 ctacgtggat acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga
     4501 tgttcatacg tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag
     4561 gtaggaatgg catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac
     4621 gaccggccat tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta
     4681 acatgtttac gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt
     4741 gaacgatacc gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt
     4801 tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg
     4861 gcgtgacttt ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac
     4921 ccatttcgtc taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt
     4981 cttcaggtcc taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag
     5041 tgtatacgtc atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc
     5101 cttcccaagt catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca
     5161 tagatggtcc gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg
     5221 gacgttggtt gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat
     5281 ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac
     5341 cgtcatgttt acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag
     5401 taccaaccca tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac
     5461 ccatcaaggc acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg
     5521 caactacttg tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt
     5581 tttcactttg agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg
     5641 ggctgtttgc ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt
     5701 ggtcagtaac acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga
     5761 atttatttac tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag
     5821 gagtttcgat cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac
     5881 cggcgcggtc acgagtcaat ccgccaggtc ctaaggctga aagacgacgt ttgtgtgtca
     5941 attcgccaag agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt
     6001 ctttgatact tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag
     6061 tatcttggat cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga
     6121 attggttttg taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat
     6181 catcgacatt gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt
     6241 cggctggacg aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt
     6301 cacgttcagg gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga
     6361 ccacaccgtc ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag
     6421 ctagtgtttc catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg
     6481 tttctggatc aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta
     6541 attttttgtt tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga
     6601 aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac
     6661 gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt
     6721 ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat
     6781 cggaaccaaa tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga
     6841 tacgtacata agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag
     6901 ggataacagt agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga
     6961 cacctggtga acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg
     7021 ttccttgttc tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc
     7081 cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat
     7141 gcgcacgagc ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca
     7201 aagatagatt gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc
     7261 cctcatctaa gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca
     7321 acacttcact gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt
     7381 gtccagccaa gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt
     7441 tacaataata tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg
     7501 caaaaaaaaa ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt
     7561 gtttccttat attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat
     7621 agtttttgca acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt
     7681 tcttctgctt tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga
     7741 caattcttaa ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga
     7801 ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac
     7861 tttagctact ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt
     7921 tgtatctatg atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct
     7981 aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta
     8041 ttttccgact tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa
     8101 ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac
     8161 tagctttagg aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa
     8221 caattggcgt attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca
     8281 aagaaggatt agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa
     8341 atgcccaaaa caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc
     8401 ctgatttgct acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca
     8461 ctatcccgat gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca
     8521 atgaaaaacc tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa
     8581 tcggcttact gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg
     8641 gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg
     8701 tcaaagtcaa agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc
     8761 tagctaaaga tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa
     8821 gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc
     8881 aagtcaaaga cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggtaaacaaa
     8941 cagggatcat ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa
     9001 cagcgaatga tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc
     9061 cagacagcat caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc
     9121 tcttttctta tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata
     9181 cgtcactttc cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg
     9241 tgcagggatc gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct
     9301 aggcttttta gggggtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa
     9361 aattcccgcc cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg
     9421 tgtgatgggt gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga
     9481 gtcattcggc ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat
     9541 cgttgtatgt ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac
     9601 tggcgataat ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat
     9661 cggttatatg atttctaatg gatgcattgc tctttctggc tccttgcttg cgcaaaacaa
     9721 cggctttgct gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat
     9781 catcgcagaa gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt
     9841 aggtgcggtc atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag
     9901 tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca
     9961 gcaaaaattc catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta
    10021 acattggaaa atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg
    10081 aaaggcatta atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg
    10141 gctggtaaat ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa
    10201 attttattga atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc
    10261 agtcgcgtat tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat
    10321 cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa
    10381 gaccgaacat ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta
    10441 tcctcagaaa tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc
    10501 acattacagc gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct
    10561 acttccaaaa cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct
    10621 tttatggtca ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg
    10681 catcaaggaa ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc
    10741 caattattag cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt
    10801 ttatcttcat aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt
    10861 ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt
    10921 gttctctcct tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa
    10981 gacaaggtac ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca
    11041 cagcaactgg aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca
    11101 ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat
    11161 gcaaaagaaa tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg
    11221 ttgacttctg aatctacgat gaaagatgtc aaactggcag cagctcaagg agattctgtt
    11281 tcgaagttat ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt
    11341 ttcgctgaac ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt
    11401 gatgaattgc ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct
    11461 gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa
    11521 gtctgtggga ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc
    11581 atcattggga tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa
    11641 gaaaaagcca tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc
    11701 agcaaaatct ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc
    11761 tataaagaaa aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact
    11821 tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa
    11881 cagaagatga gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta
    11941 tcagatttca caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca
    12001 aaagactctc cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta
    12061 aaaatatcta taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag
    12121 tcatcagttt acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata
    12181 gaccatgggt aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt
    12241 tttagctagt gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag
    12301 agtgcatagc agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg
    12361 tccagttctc gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa
    12421 tagcaaaatc agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga
    12481 tctgctttgc ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg
    12541 gaaaccggct ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa
    12601 tctggaaatc taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg
    12661 gggctctatc ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac
    12721 gttcaaaccg atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt
    12781 attttcctcc tttttattta tcctacttac tttttcctaa ttctaggata cctacttata
    12841 tgttactaca cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga
    12901 ttgaaagaaa aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt
    12961 cattaatatt ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa
    13021 aagagtataa taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa
    13081 gtttactagt cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag
    13141 cggaaacata cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg
    13201 gcttgttagg aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg
    13261 cacatacaga cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag
    13321 agcttcatga aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg
    13381 ctaattcttc aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta
    13441 acgtggatgt agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact
    13501 taactccaga tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg
    13561 aatttgctaa attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat
    13621 atactgctgc agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag
    13681 ataccgggtt tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc
    13741 aaatcattaa tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat
    13801 tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt
    13861 cggatgcgaa tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc
    13921 cttttcaagg aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg
    13981 gaacgattat aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg
    14041 aaatatttat cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat
    14101 ctaccacaag tgatagctca gattcatca
//
LOCUS       DBBGSP010000072        13917 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000072 DBBGSP010000000
VERSION     DBBGSP010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.072"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            131..505
                     /locus_tag="ACIZE9_002569"
     CDS             131..505
                     /locus_tag="ACIZE9_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HGC6094387.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="ACIZE9_002570"
     CDS             complement(619..1248)
                     /locus_tag="ACIZE9_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC6094388.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="ACIZE9_002571"
     tRNA            complement(1382..1454)
                     /locus_tag="ACIZE9_002571"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="ACIZE9_002572"
     tRNA            1668..1741
                     /locus_tag="ACIZE9_002572"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="ACIZE9_002573"
     CDS             complement(1879..2043)
                     /locus_tag="ACIZE9_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094389.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="ACIZE9_002574"
     CDS             2338..3666
                     /locus_tag="ACIZE9_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HGC6094390.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="ACIZE9_002575"
     CDS             3868..4701
                     /locus_tag="ACIZE9_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HGC6094391.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="ACIZE9_002576"
     CDS             4717..5454
                     /locus_tag="ACIZE9_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGC6094392.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="ACIZE9_002577"
     CDS             complement(5609..6577)
                     /locus_tag="ACIZE9_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGC6094393.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="ACIZE9_002578"
     CDS             6809..7642
                     /locus_tag="ACIZE9_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HGC6094394.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="ACIZE9_002579"
     CDS             7676..8515
                     /locus_tag="ACIZE9_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6094395.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="ACIZE9_002580"
     CDS             8541..9101
                     /locus_tag="ACIZE9_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6094396.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="ACIZE9_002581"
     CDS             9300..11021
                     /locus_tag="ACIZE9_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGC6094397.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="ACIZE9_002582"
     CDS             11186..12328
                     /locus_tag="ACIZE9_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGC6094398.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="ACIZE9_002583"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="ACIZE9_002583"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGC6094399.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4751 a         2298 c         2833 g         4035 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttg
//
LOCUS       DBBGSP010000073        13807 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000073 DBBGSP010000000
VERSION     DBBGSP010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.073"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="ACIZE9_002584"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="ACIZE9_002584"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGC6094400.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="ACIZE9_002585"
     CDS             complement(2260..2511)
                     /locus_tag="ACIZE9_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGC6094401.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="ACIZE9_002586"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="ACIZE9_002586"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HGC6094402.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="ACIZE9_002587"
     CDS             3461..3679
                     /locus_tag="ACIZE9_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094403.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3968..4480)
                     /locus_tag="ACIZE9_002588"
     CDS             complement(3968..4480)
                     /locus_tag="ACIZE9_002588"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGC6094404.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="ACIZE9_002589"
     CDS             complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="ACIZE9_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGC6094405.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6933..7376)
                     /locus_tag="ACIZE9_002590"
     CDS             complement(6933..7376)
                     /locus_tag="ACIZE9_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HGC6094406.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7377..8165)
                     /locus_tag="ACIZE9_002591"
     CDS             complement(7377..8165)
                     /locus_tag="ACIZE9_002591"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGC6094407.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8162..9103)
                     /gene="rnz"
                     /locus_tag="ACIZE9_002592"
     CDS             complement(8162..9103)
                     /gene="rnz"
                     /locus_tag="ACIZE9_002592"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGC6094408.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9280..9867)
                     /locus_tag="ACIZE9_002593"
     CDS             complement(9280..9867)
                     /locus_tag="ACIZE9_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HGC6094409.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10088..11401)
                     /gene="obgE"
                     /locus_tag="ACIZE9_002594"
     CDS             complement(10088..11401)
                     /gene="obgE"
                     /locus_tag="ACIZE9_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGC6094410.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11689..12699
                     /gene="gap"
                     /locus_tag="ACIZE9_002595"
     CDS             11689..12699
                     /gene="gap"
                     /locus_tag="ACIZE9_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGC6094411.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12784..13719)
                     /locus_tag="ACIZE9_002596"
     CDS             complement(12784..13719)
                     /locus_tag="ACIZE9_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6094412.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3808 a         3095 c         2435 g         4469 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa
     3721 cttttacggg ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta
     3781 aagccagttt ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg
     3841 gtctttgctt gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct
     3901 gacttttgag ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt
     3961 tttctgctta atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat
     4021 ggagatccat caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga
     4081 tcagttcgat cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca
     4141 cacgttgacc tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta
     4201 atccataagt cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa
     4261 aaccgactcc taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc
     4321 caactaccat atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc
     4381 gataagcgtc accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg
     4441 gatagtcggg aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt
     4501 gttaaccatt tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt
     4561 ttattgagcc gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg
     4621 actttttgta aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc
     4681 ataaaaatta ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga
     4741 cgtatatcaa ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt
     4801 gtgcctaccc cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg
     4861 aatgaataag accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca
     4921 actagagagt ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa
     4981 acaatcgcag cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct
     5041 aaataaaggc taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca
     5101 aatacttgca gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg
     5161 ttccattcat tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct
     5221 tcttgagtac caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca
     5281 aatttcagat gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga
     5341 aataaaaact gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca
     5401 attcgctcta ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct
     5461 ctcatcaagt caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg
     5521 acattttcac ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat
     5581 aaatctcgca tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat
     5641 cctttagctg atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc
     5701 attattttcc cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga
     5761 tggatatgat tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt
     5821 gcttttcttt cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca
     5881 tcaaacgtcg caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt
     5941 agtctgggag caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg
     6001 ctttcttcaa atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct
     6061 aatgaaacaa ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc
     6121 gctactaaat ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat
     6181 gctactccga ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga
     6241 acaatcgcat aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg
     6301 tctacaccag cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca
     6361 gtgatgatca actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca
     6421 tacccatgct caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt
     6481 gtttctttca ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg
     6541 attttttctc cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt
     6601 atcagatacg gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt
     6661 tcctcatggt aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca
     6721 cggatcattt ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt
     6781 gcttgtctca ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa
     6841 agcagaaaga aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga
     6901 tcttttgtac gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg
     6961 ggcgattgag ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct
     7021 tgtaactccg cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc
     7081 tgttcttctt ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc
     7141 tgagtcagct gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat
     7201 acaatcagtg caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag
     7261 gaagtgaagc caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata
     7321 atcaaaacta aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac
     7381 tttttgttaa aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat
     7441 tttgatgcaa cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg
     7501 cggacgatca tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa
     7561 tagcttccgc ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact
     7621 gtcgtaacag ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg
     7681 actgcaaatt tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata
     7741 gaggcgatat taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt
     7801 gtcaaaacca tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg
     7861 aatgtaagga agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc
     7921 ccgacttctt ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct
     7981 accttgaaag cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct
     8041 acaaatgcca ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa
     8101 cagatttgtg cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa
     8161 ttcatgcctc ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg
     8221 tcgtgttttc aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat
     8281 atctcgcact gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag
     8341 cagcttgatg agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa
     8401 atgtgctttc atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt
     8461 ttctcgtatc gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt
     8521 ttccattgat cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt
     8581 acagtggtcc agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat
     8641 gatcatgttc aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat
     8701 aaacagaaaa ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca
     8761 gcggataact taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc
     8821 cttttggccc gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga
     8881 gcccgggaag tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt
     8941 ttctcggacg aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca
     9001 accaaacttc attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt
     9061 ttgcaggaac acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct
     9121 ttaagttcct ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg
     9181 ggttcaaatt aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa
     9241 acagcagcga acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact
     9301 ttcattgtcg ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt
     9361 cgcatgattt tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa
     9421 gcgagtaatt tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc
     9481 ttcatcagca atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc
     9541 gaacacggtc tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc
     9601 ggcaaaccat cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat
     9661 taatccaccc gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa
     9721 ttgatgtgtc ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg
     9781 aacagcatgt aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa
     9841 atttaaaatg attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt
     9901 attttacctt taattgaaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg
     9961 gctgtgacaa aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga
    10021 tcacttctgt cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt
    10081 tgcttgccta ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt
    10141 tcgcaccgcg tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac
    10201 gcatcactgt ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac
    10261 cagataagat ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat
    10321 tgaatccata gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg
    10381 ttacttctaa caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc
    10441 cagaaattgg aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct
    10501 gttctttgaa tttcactaga ttttccggtg catccggcat atccattttg tttgccacga
    10561 tgatttgcgg acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa
    10621 gatagtcttc ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta
    10681 ctcgtgttct ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc
    10741 cttcaatcaa gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca
    10801 ttcctagatt aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg
    10861 aaataacgga tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg
    10921 ccaatacttt caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa
    10981 tttccggtgc aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac
    11041 cttttgccac aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct
    11101 ccgcatctcg gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac
    11161 cgtgcatccc tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc
    11221 gaaaatccat caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac
    11281 caccgtctcc gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca
    11341 ttccgtctcc gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca
    11401 taattaagtc ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca
    11461 aaagtcttac ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt
    11521 gtttaccttc ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag
    11581 tataattttt tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa
    11641 ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat gacagtaaaa
    11701 gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat caaagaagtc
    11761 tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat gttagcacaa
    11821 ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc aacagaagac
    11881 tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc aagcaaaatc
    11941 ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt ttatacatct
    12001 gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat ttctgcccca
    12061 gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga tgaaaacgac
    12121 aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc ttatttctta
    12181 aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta cacttccaca
    12241 caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg ttcagctgct
    12301 gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt tatccctgag
    12361 ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg ttcattaact
    12421 gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga agcaatcaaa
    12481 aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt ttctagcgat
    12541 gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt aacaactgct
    12601 ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg atttacttgc
    12661 caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc aatcgataaa
    12721 agaagccttt gactggatcc agtcaaaggc ttctttcttt tcatccccta cttttaaact
    12781 cgttcaatga acatattggc ttaaaaattg ttggactact tgctgatatt tttcaggatc
    12841 tgtcttgtat gcttccgcat gctcggctcc ttttacaaca tacttttctt ttggtccctt
    12901 cgttgcacga tagaccttat ctaacatttc aaatggtaca aatgtatctt cgtctccatg
    12961 tataaagagc attgggcgct ggtttttctt caattgttcc actgcatttg cttcaccgaa
    13021 aaagtagcca gcacggactt ttgtcactag actcgttact tgcataagcg gaaatgctgg
    13081 aagactaaac atatcgtcta gctgataagc aagctcatca tgaacggaag aataaccgca
    13141 atcttcaatg attgctttca cattatctgg tagtttttct ccgctagtca tcataactgt
    13201 tgctgctccc atgctgacac cgtatagaac gatttcttgc gattttccat tgttttctag
    13261 cactttgttt atccactgta catagtcttt acgctctggc catccaaatc caatgtaatc
    13321 cccttcgctt tttccatgtc ctcttgcatc aggaacaagg acattgtaac ccatatcatg
    13381 aaacatcttt gcgtaattgg tcatcgtttc agcgtttccc atatagccat gagccacaag
    13441 agctgttttt tcacttttcg tttcagcagg aagataaatc gctgataatt tcagaccgtc
    13501 ttttgaagtg atggtccaat cgcttcggtt ttcttttgaa ctaaaccatt tatgtgcatc
    13561 cgtttctttg gatgtctgtg ttgtaccagg tgtatcttcg tctaaaaagt ctttctcaga
    13621 aggcacaaca gcataattat aaaaataatt ccctgcaaac actaacgcaa caatcagagc
    13681 taaagcgacg cctaaaagga ttttcatcca aagtttcata aatcatccat ctcatttctc
    13741 ttttttcata taaccttgaa ttagtataat caaagaatct ctactatgca atgttcattt
    13801 ttataac
//
LOCUS       DBBGSP010000074        13727 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000074 DBBGSP010000000
VERSION     DBBGSP010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.074"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(143..1345)
                     /locus_tag="ACIZE9_002597"
     CDS             complement(143..1345)
                     /locus_tag="ACIZE9_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6094413.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1348..1542)
                     /locus_tag="ACIZE9_002598"
     CDS             complement(1348..1542)
                     /locus_tag="ACIZE9_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HGC6094414.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1589..2437)
                     /locus_tag="ACIZE9_002599"
     CDS             complement(1589..2437)
                     /locus_tag="ACIZE9_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HGC6094415.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2642..2992)
                     /locus_tag="ACIZE9_002600"
     CDS             complement(2642..2992)
                     /locus_tag="ACIZE9_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094416.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3170..4033
                     /locus_tag="ACIZE9_002601"
     CDS             3170..4033
                     /locus_tag="ACIZE9_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6094417.1"
                     /translation="MFGLVQPNKVKVGQRIKEIKDGMSLSFTELGNRLGLKKPTISSY
                     VQGYALAPKSVINQLSSISGKPVGWFYFGHVEEYIREYLFLIGQKKIVDDYPEIIEKI
                     KQEFYTGEFKNPAWENELGYPLEEFIQECFVEYSSEIMKDYVVQITKEVLEESKTLNK
                     LSSKAKEEAVTILSSGIIDYIEMSGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSY
                     LIGKLINILGTDEDTELFLSSLSMIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREK
                     TPDEFYDWFEK"
     gene            4657..5649
                     /locus_tag="ACIZE9_002602"
     CDS             4657..5649
                     /locus_tag="ACIZE9_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6094418.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5665..6549
                     /locus_tag="ACIZE9_002603"
     CDS             5665..6549
                     /locus_tag="ACIZE9_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6094419.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6598..8205
                     /locus_tag="ACIZE9_002604"
     CDS             6598..8205
                     /locus_tag="ACIZE9_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6094420.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8206..9690
                     /locus_tag="ACIZE9_002605"
     CDS             8206..9690
                     /locus_tag="ACIZE9_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGC6094421.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9867..10859
                     /locus_tag="ACIZE9_002606"
     CDS             9867..10859
                     /locus_tag="ACIZE9_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6094422.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10911..11780
                     /locus_tag="ACIZE9_002607"
     CDS             10911..11780
                     /locus_tag="ACIZE9_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005472675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGC6094423.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12200..13726)
                     /gene="guaA"
                     /locus_tag="ACIZE9_002608"
     CDS             complement(12200..13726)
                     /gene="guaA"
                     /locus_tag="ACIZE9_002608"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGC6094424.1"
                     /translation="MVLDYGSQYNQLITRRIREFGVFSELMSHRITAEEVKAMNPKGI
                     ILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGKVKPAKNREYGKAE
                     LEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCPIASIQNAERKMYG
                     IQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIREQVGDKKVLLGLS
                     GGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGKFGLNIIKVDAKER
                     FLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVIESGTET
                     AQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPGLG
                     IRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGIRSVGVMGDGRTYD
                     YTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE
                     "
BASE COUNT         4213 a         2322 c         2832 g         4360 t
ORIGIN      
        1 ttgaaaaacg ttgatttatc ggcattcccc atccatatta tatttacgtc ttattcccac
       61 tcaatatgag tagcctcgta aagaagctat tatatcagtg ctttttcagc ctattcctca
      121 ttttggtagg gaaatggtag ggttagattt ttactgcttg atttccatta aagtttgcaa
      181 ctttagattt tgttgcacag gtaaatttaa tgtttcctgt catttgttct gcaattcctt
      241 catcattacg gctccataga tgagcgtagt gctttaaagt gatttcaggg ctagaatggc
      301 ctaaccgttg cgacacgacc agaatgtctg cgttaaactc attgattagg tagctaacat
      361 gagaatgacg taatcctttt ccttgtatta ggggtacctt agctagtttg gcataacgct
      421 gaataattcg ttgaacagtt gaacgataga gtgggaggtc agtgtagcta agaataaatt
      481 gttctacacc atgatttttt tgaataactt tccacttttt tagcacttca attgtatcat
      541 cgtccagaga aatgatccgc aagccgcttt cagtttttgt gtaaggtttc cgaataaaat
      601 ctttttgatt tgtcatttcc aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca
      661 cgtcattcca attaagtgct aatccttcgc ttacacgaac accagtcatg taatatagcc
      721 agatcattaa aaaacacata tgttcgtaga aatcatcttt ataaattttt gccaaaactt
      781 cttcaaattc ttcttttgtc cagtaaggaa cgattgattt tccttttgga attgcttttg
      841 ttcttttgga aatattctca ttcagaaatt gcagggtgac cgcatagtct aatgatttac
      901 gaaacatacc gtacataagt gaactgtatg cttgtgagta tccgctatcg ttcaataacc
      961 aaattcgata attttcacaa tctcgcacat tgatttcacg aagcttctta tcaccgaaaa
     1021 attcagtaat ctgaatcaat ccacactcac gagaactcca agtacttttt tgtacgctag
     1081 ctttgtagtg tggaacgtaa gactgctcca taaattcttt gtaagttaaa tcataattcg
     1141 caaatccatt tacaaccatg tattcatttt ttatacgcat gacttctttg tgtgcttcac
     1201 gagctgatga gaatcgtttt cctagagaat cttttgttcc tttcttctgg atcctctttc
     1261 cagtcacttg atctgttcct aactcaacta gataagaaaa gcgaccattt ttatcttgat
     1321 acacacaagg gtattttgtt ttcatagtta ttcctcctgt gaaagaggaa cacctataat
     1381 ttcttcaatt acttgtcggg gtactacccc aactctttta ttattataat atggatatcc
     1441 ctgatttacc attcttgttt ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa
     1501 tcctagagcc tctaaatctt ttcgacaaat tgtatttttc attgtataaa ctcactttca
     1561 aagaaaacac tatcattggg taatagtgtt atttctttat ttttgtataa tgaacggtac
     1621 tttcttgaaa atccatcact tgttcaggac ttcccaactc atttaaagct aaagcattgt
     1681 aaaaaaatgg acgtctaact atatattcgc ttgtatatag tatatcttga ttcgtggaat
     1741 catagggttt ctttaccatc tttttggtga cagttggtag tttgagattc cgggacttga
     1801 aaaaagcttt tttcttatgc tctttcaatt ccagctcttt atcgaaatat ttgctgatat
     1861 agcgcccgcg attttcgata ctgtctacat cgatcttgtt gatcttaacg aaaccctgac
     1921 cccaaatcgt agttaaccgg ttaaatgaga taaaggggaa atcaaacaag ataatatggt
     1981 agtggattgc accgcgttgc tgcttttccc acgtggcgag atactttaaa tttgcttttt
     2041 tagttttata gaggtcataa ttcagtcgtt tgataaattt tttaaattca ttatttgcat
     2101 actcaatgtc ttgaatgttt tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa
     2161 aattcgtgtc tacaaggcgg gcaatctcaa atcgcatact ttgataatgt ttctgtttgc
     2221 gttttaaact gtcatattgt ccttgagcgg ataattcatc atagtttttt cttttttcaa
     2281 gagtaatatc attttcataa atccaagcta atttttgttt tcgttccaga tttacttcgt
     2341 tttcgatcgt tttacgtttg ggagtaatga ttgcttcata atcataaatt tcaatatacg
     2401 tgggagtttc aatgattttc tgattataag cttgcaaaaa tcatcactcc ttgttgcgta
     2461 ttcgattgtc aaagaaccag tcattttctc ctgatgttga tctataaatc aagttaaggg
     2521 ggaaggcctg cgtagcagcc cttctagcct atggggtgtt gggcggtctt aacggacaga
     2581 aacggctctg tgggcgctgc cccgccgttt cgtcctaacc acccaacact ccatagtata
     2641 gttagttttg tgtagtggta ccttgttttc tgggaatcaa agttgccgta tcagcggttg
     2701 ccgataaccc ataactgaca aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat
     2761 tggtaaatgt aattatggct aaaccttgtt gggtaagttc ttccggcgtg atcacaggat
     2821 gttcagattt gactttgaca ctgatttttt cgtagcgaag ttttggtagg atacattcgt
     2881 agctccaacc tagaatttcg ccctcctttt gccagcgagt gacattgacg acttggtatt
     2941 ctttttcgag tgtttctttt ggtaaactga gatcggtaat ttttattggc atcacaattc
     3001 tcctttttta tacgaaagtt tatacgattt gattaaaaaa tatagatggc catctacgac
     3061 ttgtattata tacgagaact tatacgtagt caagagattt tctaaaaaaa tatatacgat
     3121 tttttatacg agtgttataa tgaaaaaaat gataaggagg aatttgaata tgtttggttt
     3181 agtacaacct aataaagtga aggtgggcca acgaatcaaa gaaataaaag acggaatgtc
     3241 tctctctttt acagaattag ggaatcgatt aggtttaaaa aagccgacga tcagttccta
     3301 cgttcaaggc tatgcgttgg ctcctaagag tgtgatcaac caattatcta gtatcagcgg
     3361 aaaacctgtc ggctggtttt attttgggca tgtggaagaa tatatccgag agtatttgtt
     3421 tctcattggt cagaaaaaaa tagtggacga ttatcctgaa atcattgaga aaataaagca
     3481 agaattttat acgggcgagt tcaaaaatcc tgcttgggag aatgagctag gctatccttt
     3541 ggaggaattt atccaagaat gttttgtaga atattcgagt gaaatcatga aggactatgt
     3601 cgtacagatt acgaaagagg tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa
     3661 agcaaaagaa gaagctgtca cgattctttc atctgggatc attgactata tcgagatgag
     3721 tggtgagatc aagtatggag agaaagatcg cattgcgaaa atggtgaaag aatcaataaa
     3781 aacctttgat gtgaaacaag acctgacatt taatgattcc tatttgattg gaaagttgat
     3841 caatattctt ggtacagatg aagatacgga gctgtttctt tcttctttat caatgatatt
     3901 tactgataag catttttcca ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc
     3961 gatgcgacca gcgttaatca aactctatcg ggagaaaaca ccagatgaat tttatgattg
     4021 gtttgagaag taaaataaga aaagtggctt agattacaag ttggtgaaaa aatttttttc
     4081 agcataacat cagtaatcta taaaggggtt gttgattata ctgtagaagt taagtactca
     4141 agagattttt tgtacgtaaa caaagcaaaa aagggtgcag tttcactaga aaatgtactc
     4201 ttttttgtga tttttcttag ttatagagtt tttttgaaac tttaaaaatg agaaaacata
     4261 ttgattttaa agagtgtaga catagcttct tttgctaaat agattaaact tactggtgag
     4321 tggtcttgaa catactttta aatcacattt tactgagttt tattggattt tataattcat
     4381 tggaaacctc gtacttaatc tgtttttatc tatcgactag aatctgtata tattccagct
     4441 atcaatgagg ccgcagaaaa gggtgcttaa aaataatctg ttgtttaaaa tattattatc
     4501 agaatactta gatacaaaat tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg
     4561 atatggtaat ctataaacga aaatagtggt aacgtttcca aaatgcatct tcgttaaatt
     4621 tttatttttt taaacgaaaa tggaaacgtt tctaaaatgt attgggagga gattgaattg
     4681 gaaaagacat tgggaccagg tggtgagata agggcggtac aacgggataa aaaaaatatt
     4741 tcgaagtggg aaaaattaaa gaaacagttg cggcgtgata agtggatgta cttgttgctc
     4801 ttaccaggta tcatcatgac gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt
     4861 gcatttaaag actataatcc tatgctagga attttggaaa gtccttgggt aggactagat
     4921 cactttaggg aatttatcag ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa
     4981 attagtattt atggtttatt gttaggtttt tttccaccaa ttattttagc actgagcttg
     5041 aatcaaatta tcaataaaaa aataaaacag aaaatccagt tgattctata tgcgccgaat
     5101 tttatctcag tagttattat tgtggggatg ctgtttttgt tcctatccgc aaatggacct
     5161 attaatgggt tagtagaaaa ggttacgggg caaccaatta tgttcatgtc taatccagct
     5221 tatttcagaa cgatttatat tttatcggga atttggcaag gaatcggctg gtcatccatt
     5281 ctttacaccg caacgctggc gggagtcagt accgatttat atgaggcagc aaatatcgat
     5341 ggggcaaata ttttacaaaa gatttggcat atcgatttgc ctgcattgag gcctgtgatg
     5401 gtgatcagct tcatcttggc cgccggcggt attatgaatg taggatatga aaaagcctac
     5461 ttgatgcaaa cttcaatgaa catccctgcc tcagaaatca tttccactta tgtatacaaa
     5521 gtcggcttgc aatcaggtga ttatgcctac tctgctgctg ttggtctgtt caatatgatt
     5581 attaatgtcg ttttattact gattgtcaac aatataacca agcggctaaa cgatggtcaa
     5641 ggcttgtaat gaaaggagaa aattatgaat agtgctttat caaaaatcga ccgtcaaatc
     5701 ttatggttga atcgagtgat tgtaactttt ttagtcgtca tcaccattgt tccgctgatt
     5761 tatgtactgg tagcttcttt tatggaccca gctactttga tcaataaagg tataagcttc
     5821 aatccgaaag attggacaat acagggatat caacgggtat ttgcagatga ttccatttta
     5881 cgcggttttg taaattcgtt gttttactct tttagcttca gcttattgac tgtatttatt
     5941 acgatgatca ctgcgtatcc tttgtctcga cctaacttgg cggggaaaaa gattattatg
     6001 actttttttg tcattacaat gttcgtgggt ggtggcttga tacctaccta tttattggta
     6061 aagaacttgg gcatgttaga tagtgtatgg gcgattatcg taccaggtgc tataaatgtg
     6121 tggaatatta tcttagcccg tacctatttt agtgctttgc caaaagaact ttctgaagct
     6181 gctactatcg atggcgccaa tgacttgcaa atactgttca aagtcatgct tccattagcg
     6241 aaaccaatta tgttcgtatt gtttttatat gcctttgttg ggcaatggaa ctcatacttt
     6301 gatgccatga tttacatcaa agatcccgac ttacagccgt tgcaactcgt attaagaaat
     6361 attttgatcc aaaaccaacc ttcacaagac atggtgggag ccaatactgc catggcagaa
     6421 atgaaacaaa ttgctgagtt gatcaaatac gcaacgatcg tcatttctag tctgccatta
     6481 atcataatgt atcctttctt ccaaaaatat tttgataaag gtgttttagt tggttctgtt
     6541 aaagggtaag tattgttcac tatttgtatg aataaaaatt ataaaggaga ttttaagatg
     6601 aaagcaaaat ggatgctgcc aatcgttttt acttccgtac taattttggg ggcttgtgga
     6661 ggctcaaaag aaaagagtaa atcaagccct gattatgaac tagaaaatgt ctcttttcca
     6721 ttgaaagaaa aagtatcttt aaaaatgatg tctcaaagtg cccctttggc tcccaatgat
     6781 cctaatgaca aattgatttt ccaacgatta gaagaagaga ccaatctcca tattgattgg
     6841 acaaactaca gtagtgattt tgccgaaaaa agaaatttgg atatcgctag tggtgattta
     6901 ccagatgcca tcttcaacgc cgctgcaggt gactatgatt tattaaactg ggcggaaagt
     6961 ggcgttattg taccgattga agatttgatc gaagattata tgccaaatct gaagaaaatt
     7021 tttgatgaaa accccgaata ccgacaaatg tctactgcac ctgatggtca catttactct
     7081 atgccttgga ttgaagaatt aggcgaagga aaagagtcga ttcatacagt aaatgggatg
     7141 gcttggatca acaaggagtg gttggataat ttgggtcttg aaatgccgca aaccactgat
     7201 cagttgatga ctgtgttgga ggctttcaag acgcaagatc caaatggtaa tggtgaagca
     7261 gatgaaattc cttttagctt tattaacaat ggaggaaacg aagacttaaa atttttaatg
     7321 ggggcattcg gtctaggtga taatgatgac cacttagtcg ttgataacga tggtcaggta
     7381 caatttactg ctaacaaaga agggtataaa gaagccatca aatatttcaa tgaaatgaat
     7441 aataaaggtc ttattgataa agaggctttc gaacaagatt ggaatacgta tgttgccaaa
     7501 gggaaagaac ataagtatgg cgtgtacttt acttgggata aagcaaatat cacgggtgca
     7561 gatgatagtt atgacgtctt gccagtctta gcgggaccag atggaacgaa acatgttact
     7621 cgtacgaatg gcatgggttt ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac
     7681 ttggaactta cagctaggtg gatagataaa atgtatgaac cgttacagtc tgtccaaaat
     7741 aactggggaa cctacggtga tgaagcacag gcgaatattt ttgaattaaa ggatggtatg
     7801 ttaaaacatt tgcctttaga ggggacagca ccgggggaac taagacaaaa aaccgaagct
     7861 ggaggaccat tagcagttct tgattcttat tacggcacag tcactactat gccagatgat
     7921 gcgaagtggc gtttagattt gatgcatgac acgtatttgc catatattac agaagacaat
     7981 atctatccac gtgtcttttt agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg
     8041 gatatgtggg attacatcta tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat
     8101 gaagaatggg aagaatacct tgctgaattg gaacgtgtag gtttggaaga atggattcaa
     8161 ataaaacaaa ctggctatga taattttttg aagggagcac aataagtgtt agtagaagaa
     8221 acggcgattt tggataaagc aaatcgattt attgaaatga tgcgaggaaa agttaaccct
     8281 cagtatcgac aaaactatca tttttccgca cccatcgggt ggataaatga ccccaatggg
     8341 tttatatatt acaaagggca ttaccatctc ttctatcaat actatcctta cgatagtcga
     8401 tgggggccca tgcattgggg gcatgcgcgc agtagtgatt tggtccattg ggaagatcta
     8461 ccagtagcgt tagccccaga tcaaccttat gacagcggcg ggtgtttctc aggaagtgca
     8521 attgaaagag acggaaaact atatttattt tatacaggct gtcaagaaat tgatggtatt
     8581 agccatcagc atcaatgttt ggcggtctct gaagatggta ttcattttag caaatacagt
     8641 ggtaatcctg tggtagcaga aaaacagcta ggtgaaaatg ggctaataca agaatttcgt
     8701 gatcctaaag taattgttca caacgatggt tactatatgg tagtagctac taaatctaca
     8761 cagtctactg gtagaatagt gatgtttcaa tcgtcagatt tgtatacttg gcacttttac
     8821 tctgtgctgc tagaagggac ttcagagcaa ggaataatgt gggaatgtcc tgatttattc
     8881 catttagacg gacgagatgt cttaatcatg tctccgatac aaatcaagaa gaacggactg
     8941 gaatatcata atatcagttc taccatggct tgtattggtg aggtaaactg ggaaacaggt
     9001 cagatgatag ttgataattt ccatgaaatg gattttggaa tggattttta tgcaccacaa
     9061 acaacaagag atcctaatgg tggacgggtg atgattgctt ggatgcagat gtgggatcgt
     9121 acattgccta cacatgagtt aggccatctt tgggcaggct ctatgagttt gccccgagag
     9181 ttaagagtga aaaaaaatcg attggtacaa aaacccatct caactgtata tagtcattta
     9241 gtttatcaac aaggcagtga aaatattgca gtgactgaca catcagtcgt atttcgaaac
     9301 gcgctgtctg attcttcata tttacatcta gtcgcagatt tggagaaagc tgaagttttt
     9361 acaattgaat tactgcggtc taagacggat tgtctcaaac tagcctatga cactgctaca
     9421 caggtttttg aattggatcg tcagaaacta ggaagagagc ttacaggggc ggaagaagac
     9481 cctctgaatg tacgaaaagt tgaagtacct ttgattgata atcagctcgt tcttgagatt
     9541 tttagagata cctcatcaat tgaagtcttt attaatgggt tagaagttat gacggctact
     9601 ttctatgagc tggaaaaagc tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt
     9661 caagcttttg aaacagcgag tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt
     9721 atttaatagg ttttgaagga taatgttttt agaaaagaac agatagctag atttcccatg
     9781 gatttgctat tagtattttg aaaaaattag taatttatga caaaattcat tatactaaac
     9841 ttgtgcagaa atgtgaggga tcaactatga aagcaacaat gaaagatgtc gcaaaattag
     9901 caggtgttgg agtaggaact gtttcccggg tattgaataa cggttctgtt aaagcttcta
     9961 ctagagaaaa agttgaagca gcaatgacag agttaaacta tcaaccagat ttttatgccc
    10021 gggggttaaa gatgaagcat acgaacacgg ttgctttgat tctacccacg gtatggcatc
    10081 cattttttgg cgaatttgcc taccatgtag aaacagcatt agaaagacaa aactacaagc
    10141 tttatttgtg taactccagt ggtaatagtg aaaaagaaca agaatatatc cagatggtca
    10201 gccaaaataa agtagacggc atcattggaa ttacttattc agatatcgat gaatacattt
    10261 cgagtaatct gccttttgtt agtattgacc gttatttcac tgaagaggtg atttatgtga
    10321 ccgctgacaa tgcggccggt ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc
    10381 agaatgtagc atatatcggt gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa
    10441 aatattttga aatcgagtgc cgtcaactgg ggatttccta taaagcgtta gatatgttag
    10501 aacctttaga ccatctctca gaacgtgtaa caaatttttt gttagagaat cccgatatcg
    10561 atgggatttt tacgatcaac gatccaatgg cattagctgt cattgatatg cttgaaaaaa
    10621 tagggaaaaa cgtaccagag gatgtccaag ttatcggatt tgatggtcaa aagatgacag
    10681 aaggagatcc ttatctagtc tcaacgattg cccaacctac aaagcaaatg gcggaagtgg
    10741 cagtggcaaa attaattgct gtcattaatg gagagacagt agaaaaacgt accgtattgc
    10801 cgattgaatt tggcgaaggt gacacaacga aacctttagt gagaaacgat tttgcttagt
    10861 gcaaatacgt ttcttttttt gaaaatgagt gaatgaaagg tgtagataaa atgttatatg
    10921 gtggaataga agccggtgga acaaagtttg tctgtgggat tggtaatgaa caattacaag
    10981 tgatagaacg gaaaagtttt cctaccacaa caccagaaga aacgatggag caagtgtttg
    11041 atttctttga taagtacaaa ggaaatatcg catcaattgg tgtaggagca tttgggccta
    11101 ttgatattca aatcgaatca agaacttacg gatatatcac caacacaccg aagttagctt
    11161 ggcaaaatta tcattttgta ggagctttgg aaaacgcctt gtcggttccc atctattgga
    11221 ctaccgatgt aaatgctgct tgttatggag aatatatggc agggtatgga aaaggtaaaa
    11281 atagtgttct gtattacacc gttggtacag gtgttggtgg tggtgctgta gtggatggga
    11341 aaatagtcgc aggttttagt catcctgaaa tgggacatat gctcttacaa cgtcataatg
    11401 aagatcaatt tgaaggaatc tgtccttttc atcatgattg tttggaaggg ttagcatcag
    11461 gacctgcgat tgaaaaacgc tttggaagaa aagcccagac tatctcattt gatcatcctt
    11521 attggacgat tgaggcagat tatcttgctc agtgtgtgta taacacaacg ttactatatg
    11581 caccggaagt aataatttta ggcgggggtg taatgaaaca gccgcaacta ctcgagttga
    11641 ttcgccaatc gtttaaagaa aaaatgggtt cctacgtgga tacgcctact ctcgaagaat
    11701 atctactaac tccaaggctt gctgacaatg cgggcttgat tggctgccta gctttagcaa
    11761 taaagaaact caatcattag aatagtattt attagaacta ttcataacat accggaagtt
    11821 taaaagggta ttctgaaact taaatagtct caattcattc ttctttcttg agaatctgag
    11881 tagagacttt tattctgttt caaattaata taattacgaa atgatattga gtacaagaaa
    11941 gttcttttta ccagatcttt taaatcgaaa aatctgatat atatatttat agtactaaaa
    12001 atctgattag ataaaaagct aattcaatag gaaaataaag gtagtgaata aaagcaaagc
    12061 ccttgttagt agttaatcta acaagggctt tggtagggaa aatggtagga aaccatctta
    12121 ttttttacga aaatcaggaa ctttagtaat tgaataatgt tgatttatag gtattcctca
    12181 tccatattat gttggctctt tattcccact ccactgttgc aggtggtttg ctggtaatat
    12241 catacacgat acggttaacg tgtgcgactt catttacgat acggacactg attttttgca
    12301 agacttccca agggatacgg gcaaagtcag cggtcatgcc gtcaatagaa gtgacagcac
    12361 ggatacctac agtgtagtca tacgtacggc catctcccat aaccccaaca gagcgaatgc
    12421 ctggtaggac ggtgaagtat tgccagatgt cgcgatctaa accggcattg gcgatttctt
    12481 cgcgcaagat agcgtctgat tcacggacga tttctaattt ttcttctgtc aattcaccaa
    12541 ggacacgaat acctaagcct ggtccaggga atggttggcg ccaaacgatg ctgtcaggca
    12601 tgcctaattg ggtacctaat tcacgtactt cgtctttgaa caatgtgttc aatggctcga
    12661 tcagcttgaa ttgcatgtct tcaggtaatc cacctacatt gtgatgtgat ttgatggttt
    12721 gggcagtttc agttcctgat tcgatcacat cggtataaag ggttccttgt gcaaggaaag
    12781 aaacgccttc ttcaccggca agtttggttg cttcatcatc gaagacatat acaaattcat
    12841 ttccaatgat tttacgtttt tcttctggat cagacacgcc agcaagtttt gataagaaac
    12901 gttctttggc atcgactttt ataatgttca agccaaattt tccgccaaga ctttccataa
    12961 cttgttctgc ttcaccttta cgcaacaata cgtgatcaac gaagatacat gttaattgat
    13021 cgccgatcgc tttttgtaaa agaacaccaa caacagagga atctactccg cctgaaaggc
    13081 ctaataaaac ttttttgtca ccgacttgtt cacgaatttt tgcgatctcc atgtcgatga
    13141 agttatccat tgtccagtca ccagtacatt ggcagacatc tagtgtaaaa tggcgcaaca
    13201 agtcatttcc atattcggaa tggcgaactt ctgcatggaa ttggattccg tacattttgc
    13261 gttctgcatt ttggatcgat gcgatggggc aatctttgct ggtagcaacg acatcgaaat
    13321 cagtcggtgc ttgggtaact aggtcaccat gactcatcca aacggtttgt ttttcaggag
    13381 tgttttggaa aagggccgct tctgcagaag tgatttccaa ttctgctttt ccgtattcac
    13441 ggtttttggc tggtttaact tttccgccta atttataagt aatcaactgc ataccgtaac
    13501 agattcctaa aactgggatc cccaaatcaa aaatcttttc atcaatacca aaggccttct
    13561 catcataaac actgtttggt ccgccagaaa ggatgattcc tttagggttc attgccttta
    13621 cttcttctgc ggtaatgcgg tggctcatca actctgagaa aacaccgaac tcacgaatac
    13681 ggcgagtgat cagttggtta tactgactac cgtaatcaag tacgata
//
LOCUS       DBBGSP010000075        13696 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000075 DBBGSP010000000
VERSION     DBBGSP010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.075"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            312..482
                     /locus_tag="ACIZE9_002609"
     CDS             312..482
                     /locus_tag="ACIZE9_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094425.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            496..1098
                     /locus_tag="ACIZE9_002610"
     CDS             496..1098
                     /locus_tag="ACIZE9_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6094426.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1114..1791
                     /locus_tag="ACIZE9_002611"
                     /pseudo
     CDS             1114..1791
                     /locus_tag="ACIZE9_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2102..2599
                     /locus_tag="ACIZE9_002612"
     CDS             2102..2599
                     /locus_tag="ACIZE9_002612"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HGC6094427.1"
                     /translation="MLFLRDGEIKATLTTMMNKLAFSHKLILEPLFKSVSQIDEESDR
                     ERMDAIDKLMEQLLEERNTLIALMSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTN
                     SASGVLRANEIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLK
                     EKVVR"
     gene            2600..3016
                     /locus_tag="ACIZE9_002613"
     CDS             2600..3016
                     /locus_tag="ACIZE9_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HGC6094428.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3036..4580
                     /locus_tag="ACIZE9_002614"
     CDS             3036..4580
                     /locus_tag="ACIZE9_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6094429.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            4723..4947
                     /locus_tag="ACIZE9_002615"
     CDS             4723..4947
                     /locus_tag="ACIZE9_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094430.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            4962..5831
                     /locus_tag="ACIZE9_002616"
     CDS             4962..5831
                     /locus_tag="ACIZE9_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HGC6094431.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            5812..6546
                     /locus_tag="ACIZE9_002617"
     CDS             5812..6546
                     /locus_tag="ACIZE9_002617"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6094432.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            6579..7487
                     /locus_tag="ACIZE9_002618"
     CDS             6579..7487
                     /locus_tag="ACIZE9_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HGC6094433.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            7484..8026
                     /gene="sat4"
                     /locus_tag="ACIZE9_002619"
     CDS             7484..8026
                     /gene="sat4"
                     /locus_tag="ACIZE9_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HGC6094434.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            8119..8913
                     /locus_tag="ACIZE9_002620"
                     /note="aph(3')-IIIa"
     CDS             8119..8913
                     /locus_tag="ACIZE9_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HGC6094435.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            9189..9320
                     /locus_tag="ACIZE9_002621"
                     /pseudo
     CDS             9189..9320
                     /locus_tag="ACIZE9_002621"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            9396..9889
                     /locus_tag="ACIZE9_002622"
                     /pseudo
     CDS             9396..9889
                     /locus_tag="ACIZE9_002622"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            10059..10955
                     /locus_tag="ACIZE9_002623"
     CDS             10059..10955
                     /locus_tag="ACIZE9_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6094436.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
     gene            11054..11263
                     /locus_tag="ACIZE9_002624"
     CDS             11054..11263
                     /locus_tag="ACIZE9_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HGC6094437.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            11280..11552
                     /locus_tag="ACIZE9_002625"
     CDS             11280..11552
                     /locus_tag="ACIZE9_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HGC6094438.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            11554..12417
                     /locus_tag="ACIZE9_002626"
     CDS             11554..12417
                     /locus_tag="ACIZE9_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HGC6094439.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(12680..13417)
                     /gene="erm(B)"
                     /locus_tag="ACIZE9_002627"
     CDS             complement(12680..13417)
                     /gene="erm(B)"
                     /locus_tag="ACIZE9_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HGC6094440.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(13542..13625)
                     /locus_tag="ACIZE9_002628"
     CDS             complement(13542..13625)
                     /locus_tag="ACIZE9_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HGC6094441.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
BASE COUNT         4853 a         2128 c         2848 g         3867 t
ORIGIN      
        1 tatgatacgt gtttgttttt ctgtgctgtt tagtgaatga ttagcagaaa tatagagagt
       61 aagattttaa ttaattatta gggggagaag gagagagtag cccgaaaact tttagttggc
      121 ttggactgaa cgaagtgagg gaaaggctac taaaacgtcg aggggcagtg agagcgaagc
      181 gaacacttga tcttttaagt tgctatcttt ttaaggtcaa tagagtatac ttatttgtcc
      241 taatatggtt ttagcagtat aattgacttg gtgaataggt catttaagtt gggcataata
      301 ggaggagtaa aatgaaaaaa tttatttatc gagttttaga aaatgacgaa gtggtggcta
      361 tttttaatga gcaacaatat gcgcaagatt ttatcgctta cgaaaagaca atttctgata
      421 agcaatttga aattgaaaaa gtagatatag ctgattggtt attgcaaccg agagaatttt
      481 agaggttggt tgaaaatggc taaaattggt tatgcacgtg tcagtagcaa agaacagaac
      541 ttagatagac aactgaaagc gttagagggc gtttctaagg tcttttcaga caaattaagc
      601 ggtcaatcgg tcgaacgccc acaattacaa gctatgctta actatattcg tgaaggggat
      661 atagttgttg ttactgaatt agatcgatta ggacgaaata ataaagaatt aacagaattg
      721 atgaatcaaa ttcaaattaa gggggcaacc ctggaagtct taaatttacc ctcaatgaat
      781 ggtattgaag atgaaaattt aagacggctg attaataatt tagtgattga attgtataag
      841 taccaagcgg aatctgaacg caaacgaatt aaagaacgcc aagcccaagg aattgaaatt
      901 gctaagaaaa aaggaaaatt caaagggcga caacctaaat tcaaagaaaa tgatccacgt
      961 ttacaacacg ctttcgattt atttttgaat ggttgttccg ataaagaagt tgaagaacaa
     1021 actggaatta atcgccgaac gtttagaagg tatcgatcaa gatacaacgt gacagtagat
     1081 caaagaaaaa aacaatgaaa agagggatag ttaatgagta cggttatttt agctgaaaaa
     1141 ccaagccagg cattagccta cgcaagtgct ttaaaacaaa gcaccaaaaa agacggttat
     1201 tttgagatca aagacccact atttacagat gaaacgttta tcacctttgg ttttgggcat
     1261 ttagtcgaat tagcagaacc aggtcattat aacgaaaagt ggcagaactg gaaacttgaa
     1321 tctttgccga tttttcctga tcgatacgat tttgaagttg caaaagataa gggaaagcag
     1381 tttaaaattg ttgctgaact tctcaaaaag gcaaatacaa ttattgtcgc aacagatagc
     1441 gacagagaag gtgaaaatat cgcctggtcg attatccata aagcaaatgc cttttctaaa
     1501 gataaaacgt ataaaagatt atggatcaat agcttagaaa aagatgtgat ccgaagcggt
     1561 tttcaaaatt tgcaaccagg aatgaattac tatccctttt atcaagaagc gcaaacacgc
     1621 caaattgccg attggttgat cggcatgaac gcaagccctt tatatacctt gaatttacaa
     1681 caaaaaggcg tacaaggtac attttcatta ggacgtgtac aaacaccgac tttatatctc
     1741 atttatcaac gccaggaagc aatagaaaac tttaaaaaag aacctttttt cctgaataat
     1801 tcatagtttt actaatagtc tttcctaaca ttgatttaat agtctttaaa gtattctgct
     1861 tcatcaccca ttaggtgatg aaaaaagaac ccctttctga tttagcggac aaatactttg
     1921 acctaatctc agaagatata aaagaaaaaa taataaaata tccgatttat actttgtata
     1981 aagaactaaa gtagttagca aatcatttac agcaaatcac tatgttccac ataccatttt
     2041 acatacttac cttatccacg acacatgttg agatagtatc gaagataaag aaagttgctc
     2101 catgttgttt ttgcgagatg gggaaatcaa agccacattg acaaccatga tgaataagct
     2161 tgctttcagt cataagctaa tcctagaacc acttttcaag tcagttagcc aaatcgatga
     2221 agaaagcgac cgtgaaagaa tggacgctat tgataagcta atggagcaac tattggaaga
     2281 acgcaatacc cttattgcac tgatgtccaa aggtttccta gaacctgctc tttttaatca
     2341 ggaacgaaat gttttagata gtgagattaa aaatcttact accgaaaaaa caaacctggt
     2401 aacgaactct gcgagtgggg ttttgcgagc aaacgagata aaggacctca ttaattatgt
     2461 gtcagcagat aattttaatg gtgactacac ggaagaacta tttgaagaat ttgtagtgaa
     2521 catcattgta aattccaggg atgagctgac attcaatttg aaatgcggtc tttccctgaa
     2581 agaaaaggtg gtgagataaa tggcatatat tccatatgga tacaaaattc aagatggagt
     2641 ggttactgtc gatgaaaagg cagcaggtca agtaaaggta ttctttgaga aatacatatc
     2701 aggactatcc cttacagtgg ctggcgaaca ggcaggtatt gaaaagacac attctgtgat
     2761 ggggcgcatt ttgaaaaacg tcaactacct tggaaatgat acgtatccag caattattga
     2821 taaagagata tttgataaag ctgaagaagt tagagataaa cgtgcaaagg atttaggacg
     2881 agtggtagag cttgccgctt tcacctctcc ccctcccaaa gaacgattca aaatgaaaaa
     2941 ggcagataat aagatgccag tggatccttt tgaacgagca gaatacttat acagtctgat
     3001 agaaagcgag gaataaagtg acagagaaaa atataatggt tattcctgct cgtaaaagag
     3061 taggaagtac agccgcaaaa gaaaagataa agaaacttcg tgttgctgcc tattgccgtg
     3121 tttctacaga aacagaagaa caaaattcta gctatgaggt tcaggtctca cactatacag
     3181 agtttataaa gaaaaataat gaatgggagt ttgctggcat ctttgcagat gatggtatct
     3241 ctggtacgaa cactaaaaag cgtgacgaat ttaatcgcat gattgcagag tgtatggacg
     3301 gtaacatcga catggttatt acaaaatcca tcagccgatt tgcgcgtaac accctagact
     3361 gccttcaata cattagacag ctcaaggata agaacatatc agtttatttt gagaaagaga
     3421 acatcaacac cacggatgcc aaaggtgagg ttttgctgac tattatggca tctttggcac
     3481 agcaggaaag ccagagcctt tcacaaaacg ttaagcttgg gctacagtac cgataccaac
     3541 aaggaaaggt gcaggtcaac cataagcgat ttatgggcta cacgaaagat gaagatggaa
     3601 atttaactat tgtccccgaa gaagctgaga ttatcaaacg catctaccga gaataccttg
     3661 agggtcagag tctagtgggc attggtcgag cccttgaaaa ggatggtatt ttaacagcag
     3721 cgggaaaacc aagatggcga ccagaatcag ttaagaagat acttcaaaac gaaaaataca
     3781 tcggagatgc ccttctgcaa aagactgtca cagtagattt tctgaccaag aaacgagtga
     3841 aaaatgaagg gcatgttccc caatattatg ttgaaaatag ccatgaagcg attattccta
     3901 aagagttatt tttgcaggcg caagaagaaa ttcatcggag aagcaatatc tacacaggag
     3961 aaggcaagaa caaaagaatt tacagtagca agtacgcttt aagtgccatc accttctgtg
     4021 gagattgtgg cgatatttat agacgggtct attggaatat ccacggaaga aaagaatttg
     4081 tctggcgatg cgtgactaga atcgagcaag gtcctgaagt ttgtaagaac cgaaccgtaa
     4141 aagaagatga actttatggt gcagtaatga ctgcgattaa taagctactt gcaggtggga
     4201 acaatatgat aaagacactg gaagagaata ttcatgctgt gattggcgaa accacagaat
     4261 accaaatttc agagattaac aactcactag aggaaaaaca aaaagaacta atcaagctgg
     4321 cgaacaaggg tcaagactat gaccacttag cagatgagat tgatgagctg agagacaagc
     4381 gacagatcct tttagtagaa gatgcctccc tcagtggcga gaacgagcga atcaatgagc
     4441 tgattgaatt tatccgcaag aacaaattcc gcaccttaga atatgatgat aagcttgtaa
     4501 ggaagataat ccagagcgtt acagtctatg aaggccactt cgtcatagcc ttcaaatctg
     4561 gcatcgaaat ggaaatatga aaaccagaag taaatagccc atgactctac agtagagttg
     4621 tgggttttct tttgcttgct gattataata atattttaat aactattgtg tttatcaacc
     4681 aaatggttta taatattctt agcgtaaact tggaggtgct gtatgactac ggcagaaatg
     4741 attaaagaac tgtgtgagca aatgaatata agtgtttccg aacttgctag acgtattggc
     4801 cagactccac agaatttcaa taaaaaatta caacgagaaa cagtaacctt ggatgagttg
     4861 aaggccattg ctgatgtgct aggtgtcaag tttgtgcagg catttatttt accagatgga
     4921 gaagaaataa aaatatctaa cgaataaagg aggatgttta tatggtaggt aatgttattc
     4981 aaatagtaac agagaaatta tcatctttgc cttttataga aggcatcgta ttagggggct
     5041 cacgtgcaag aggcacccat acagaaaatt ctgatataga tatcggaatc tattacaatt
     5101 cagactcatt tgacctgaca gcgattaatc aaattgctac agagttggat gatgagaata
     5161 gaaacaacct tgttgtacct cccggagcgt ggggtgattg ggttaatggc ggtggatggt
     5221 tagttataaa cgggtgtcat gttgacttga tattacgtga tataaaacgg gtggaacaaa
     5281 taatcaaaga tacggagcaa ggaattgtta ctgccaatta tcagaccggg catccccatg
     5341 gttatataag tgctatgtat cgtggagaat tagcgattag taaaatacta tatgctaaga
     5401 acgaaagctt atgcgaatta aaaaagcagg cagaaattta ccctactgct ctaaagaaaa
     5461 gcttgatgaa cttttttata tttgaagctg aattctcttt aatgtttgta aaagcaaatg
     5521 cgggggcaga ggataaatat tatattgcag gccatgtttt tcgtattatt tcatgcttaa
     5581 atcaagtact atttgcatgt aataatgctt attgcattaa cgaaaagaaa gctataaaac
     5641 tgcttgaaac ttttgaatat aaacctgaaa aatatgccga aagagttaat catatttttg
     5701 aagtactcgg tctttctctt tttgaatgct acgacatgac cgagaaactt tataaagaag
     5761 tgaatgaaat tgtatcggag ataaataact ttttaaacga ggagagttca gatgaaagaa
     5821 aacaaatatg atgataatat attttttcaa aaatacagtc aaatgagtcg ctcgcagaaa
     5881 ggactggctg gtgcgggaga atgggagact ttgaaaaaga tgctacctga ttttaagggt
     5941 aagcgtgtgc ttgatttagg atgcggctat ggatggcact gtatatatgc gatggaaaac
     6001 ggtgcttcct ctgtagtagg tgttgatatt tctcataaaa tgctcgaagt agcaaaagga
     6061 aaaacccatt ttccacagat tgaatatgaa tgctgtgcca tagaagatgt ggatttccca
     6121 gaggagagct ttgatgtaat actaagttcg cttgcgtttc attatgtagc agactatgag
     6181 aatttaataa aaaagatata taggatgctg aaggctggtg gcaatttagt ttttacagtt
     6241 gaacatcctg tttttactgc tcatggaaca caagactggt attataacga aaaaggagaa
     6301 atactgcatt tcccggtgga caattattat tatgagggca aacggacagc tatgtttttg
     6361 gaagaaaagg ttacaaaata tcatagaaca ctgaccacat atctaaatac actgctttca
     6421 aatagtttta taataaatca gattgtggag ccacagccgc cagagaacat gatggatatt
     6481 ccggggatgg cggatgaaat gcgacgccca atgatgctga ttgtatcggc aaaaaagaag
     6541 atgtaataat atagaaaaaa taaacgagga gtatgtaaat gagatcagaa aaagaaatga
     6601 tggatttagt actttcttta gcagaacagg atgaacgtat tcgaattgtg acccttgagg
     6661 ggtcacgcgc aaatattaat atacctaaag atgaatttca ggattatgat attacatatt
     6721 ttgtaagtga tatagaaccg tttatatcta atgatgactg gcttaatcaa tttgggaata
     6781 taataatgat gcaaaagccg gaggatatgg aattattccc acctgaagaa aagggatttt
     6841 cctatcttat gctatttgat gattacaata aaattgatct taccttattg cccttggaag
     6901 agttagataa ttacctaaag ggcgataaat taataaaggt tctaattgat aaagattgta
     6961 gaattaaaag ggacatagtt ccgactgata tagattatca tgtaagaaag ccaagcgcaa
     7021 gggagtatga tgattgctgc aatgaatttt ggaatgtaac accttatgtt attaaaggat
     7081 tgtgccgtaa ggaaatttta tttgctattg atcattttaa tcagattgtt cgccatgagc
     7141 tgctgagaat gatatcatgg aaggtcggca tcgaaacagg ctttaaatta agtgtaggca
     7201 agaactataa gtttattgaa aggtatatat ccgaggattt gtgggagaaa cttttgtcca
     7261 cctaccggat ggattcctat gaaaacatat gggaagcatt atttctatgc catcaattgt
     7321 tcagggcggt atccggtgag gtggcggaaa ggcttcatta tgcctatccg gagtatgata
     7381 ggaatataac aaaatatacc agggacatgt ataaaaaata cactggtaaa accggctgcc
     7441 tggatagcac atatgccgct gatatagaag agaggcggga acagtgatta cagaaatgaa
     7501 agcagggcac ctgaaagata tcgataaacc cagcgaacca tttgaggtga taggtaagat
     7561 tataccgagg tatgaaaacg agaattggac ctttacagaa ttactctatg aagcgccata
     7621 tttaaaaagc taccaagacg aagaggatga agaggatgag gaggcagatt gccttgaata
     7681 tattgacaat actgataaga taatatatct ttactaccaa gacgataaat gcgtcggaaa
     7741 agttaaactg cgaaaaaatt ggaaccggta cgcttatata gaagatatcg ccgtatgtaa
     7801 ggatttcagg gggcaaggca taggcagcgc gcttatcaat atatctatag aatgggcaaa
     7861 gcataaaaac ttgcatggac taatgcttga aacccaggac aataacctta tagcttgtaa
     7921 attctatcat aattgtggtt tcaaaatcgg ctccgtcgat actatgttat acgccaactt
     7981 tgaaaacaac tttgaaaaag ctgttttctg gtatttaagg ttttagaatg caaggaacag
     8041 tgaattggag ttcgtcttgt tataattagc ttcttggggt atctttaaat actgtagaaa
     8101 agaggaagga aataataaat ggctaaaatg agaatatcac cggaattgaa aaaactgatc
     8161 gaaaaatacc gctgcgtaaa agatacggaa ggaatgtctc ctgctaaggt atataagctg
     8221 gtgggagaaa atgaaaacct atatttaaaa atgacggaca gccggtataa agggaccacc
     8281 tatgatgtgg aacgggaaaa ggacatgatg ctatggctgg aaggaaagct gcctgttcca
     8341 aaggtcctgc actttgaacg gcatgatggc tggagcaatc tgctcatgag tgaggccgat
     8401 ggcgtccttt gctcggaaga gtatgaagat gaacaaagcc ctgaaaagat tatcgagctg
     8461 tatgcggagt gcatcaggct ctttcactcc atcgacatat cggattgtcc ctatacgaat
     8521 agcttagaca gccgcttagc cgaattggat tacttactga ataacgatct ggccgatgtg
     8581 gattgcgaaa actgggaaga agacactcca tttaaagatc cgcgcgagct gtatgatttt
     8641 ttaaagacgg aaaagcccga agaggaactt gtcttttccc acggcgacct gggagacagc
     8701 aacatctttg tgaaagatgg caaagtaagt ggctttattg atcttgggag aagcggcagg
     8761 gcggacaagt ggtatgacat tgccttctgc gtccggtcga tcagggagga tatcggggaa
     8821 gaacagtatg tcgagctatt ttttgactta ctggggatca agcctgattg ggagaaaata
     8881 aaatattata ttttactgga tgaattgttt tagtacctag atttagatgt ctaaaaagct
     8941 ttaactacaa gctttttaga catctaatct tttctgaagt acatccgcaa ctgtccatac
     9001 tctgatgttt tatatctttt ctaaaagttc gctagataga gttctatatt agagatgtaa
     9061 agagttttgg tgaagaggtt tgtgagtatg gcttttataa ccagggtgca atgagaagca
     9121 ctaacagcag ctagcttaag aacgcatagg atatactttt tatggaagtc acagaggagg
     9181 aataaaattt gaacaggatt aacagagtaa cctctattct tattcagctg caatcaaaaa
     9241 aaataattcc tgccaaagaa attgcacagc gatttaatat aagcttaagg acagtttaca
     9301 gagatatccg gacacttgaa gaagccggaa taccaattgg atctgaggcc ggaaaaggat
     9361 attttcttgt agagggcttc ctacttccgc cggtaatgtt tacagcggcg gaagtgggtg
     9421 cattgattac agcagggaaa tttttaaatt gccatggaga tgaatcattt ataaaggatt
     9481 ttgattcagc tatgtataaa atcaaatcta ttttgaagca tggtgaaaaa aactatgcac
     9541 aggagttgga gaacagtatt aacgtgtaca gcacatctgg acagaaaaat acattggcgg
     9601 ataacgttat tgcagcaatt cagactgcaa tctgcaataa aagggtaata tcaattcaat
     9661 atcctgcatc aggagggcaa gaaccggaaa gcagaatgat agagcctata tcactggggt
     9721 tttatgaaca gaactggtac ttaatcggtt ttgcaggcta agaaatgaat ataggaattt
     9781 tcgtgtggat cggattaaaa gcatttgcat agaagaagag ctctgtcaaa gccatgatgg
     9841 ctctttggaa caaatattaa aacaaatgct ttcatataaa aaactatatg ccctacaatg
     9901 ccgttgtaaa aattggggaa aagggatata ttgattttat atctttctca aaataaatat
     9961 aaaagccctt taaagagggc ttttatatat taatcacaaa tcacttatca caaatcacaa
    10021 gtgattaatc acaaatcact tgtgatttgt gattcttaat gatacaatat tactatacaa
    10081 aaaaagaatg gggcgtagtt atggagaagg aaaaactaaa aatacttgaa gaattaagac
    10141 gtattttaaa caataaaaat gaagcaatta ttatcttgaa taattacttt aaaggtggtg
    10201 ttggaaagtc caaattatcg actatgtttg cttacttgac agacaaattg aatttaaaag
    10261 ttttaatgat cgataaggac ttacaggcaa cattgacaaa agacttagca aaaacttttg
    10321 aggtagaatt gccacgtgtc aatttttatg aaggcttgaa aaatggaaac ttggcttctt
    10381 ctattattca tttgactgat aatttagact tgatccctgg cacgtttgat ttgatgttac
    10441 tgccaaaatt aactcgctca tggacgtttg aaaatgaaag tagattgctt gctactcttt
    10501 tagcaccttt aaaaagtgac tatgatctta ttattattga tactgtacca acgccaagcg
    10561 tttatacaaa taatgcaatc gtggcgagtg attacgttat gatcccttta caagcagaag
    10621 aagaaagtac aaacaacatt caaaactata tttcctattt gattgatttg caagaacagt
    10681 ttaaccctgg actagatatg attggttttg ttccttattt agttgatacg gacagcgcaa
    10741 cgataaaatc aaacctggaa gaactgtaca aagaacataa agaggataat ttggttttcc
    10801 gaaatattat caagcgaagt aataaagtaa gtacttggtc taaaaatggc attacagaac
    10861 acaaaggcta tgacaaaaaa gttttgtcta tgtatgagaa cgtatttttt gaaatgattg
    10921 agcgaatcat tcaattagaa aatgaaaaag aatagaatca caaatcacaa gtgattaatc
    10981 acaaatcact tgtgatttgt gataggtgat gataaaataa atagtaagaa gaaatagaaa
    11041 gaagtgagcg atcgtgggaa atttaggcgc acagaaagca aaacgaaatg atacgccaat
    11101 cagcgcaaaa aaagatataa tgggggataa gacggttcgt gttcgtgccg acttgcacca
    11161 tatcataaaa atcgaaacag caaagaatgg cggaaacgta aaagaagtta tggatcaagc
    11221 cttagaagaa tatatacgga aatatttacc tgacaaactt taaaaggagt gaaaatgaaa
    11281 tggcagttac gtatgaaaaa acatttgaaa ttgaaatcat taatgagtta tcggcaagtg
    11341 tttataatcg ggtattaaat tatgttttga atcatgaact agatactaaa aatactcgtt
    11401 tactagaagt gaatctttta aatcaattag aagtggcaca agaagttgat ttatttcaac
    11461 aaccatttga agaattacaa gctattcatg agtattggcg gtcaatgaat caatattcaa
    11521 aacaaatttt gaataaagag aaagtggctt aacatggcga atattactga cttcaccgaa
    11581 aagcaatttg aagatcgttt agaaaagaat gttgaacgac taactaaaaa tagactagcg
    11641 gttgaatcgc caaccgcttt tttacttggt gggcaaccag ggtcagggaa aaccagtttg
    11701 cgatcagcaa tttttgaaga aacacaaggg aatgttattg tcattgataa tgataccttt
    11761 aaacaacagc acccaaattt tgacgaatta gtgaaactct atgaaaaaga cgtagtaaaa
    11821 cacgttaccc cttattcgaa tcgcatgaca gaagcactta ttagccgttt aagcgatcaa
    11881 ggctataatt tagtgattga aggaacagga cgaacaacag acgttcccat tcaaacagcc
    11941 acaatgcttc aatctaaagg ttatgaaaca aaaatatacg tcatggcagt accgaaaatt
    12001 gaatcatact taggaacgat tgaacgatat gaaaccatgt atgcagatga tccaatgaca
    12061 gctagggcaa caccaaaaca agcgcatgat attgttgtca aaaacttacc gaccaattta
    12121 gaaacccttc ataaaacggg cttatttagc gatataaggc tttacaatag agaaggagtg
    12181 aaactctatt caagcttaga aacgccttcc attagtccga aagagacctt agaaagagaa
    12241 ttaaatcgta aagtatcagg gaaagaaatt caaccgactt tggagagaat agagcaaaaa
    12301 atggttcaaa atcaacacca agaaacccct gaatttaaag caattcaaca aaaaatggaa
    12361 agcttgcagc tacctacacc accaataccc aaaacaccta aacttccagg tatttaaacc
    12421 ttaaaaaagg aaaagagtag ttaccaaaaa acggtaacta ctcttttttt ataaaaacat
    12481 ttcctcatgt tggggtcccg agcgcctacg aggaatttgt atcgataaga aatagattta
    12541 aaaatttcgc tgtttttttc taatttcatt ttgaggtgaa ttaattggta gttattagag
    12601 gtgccctata cctaataatt tatctacatt ccctttagta acgtgtaact ttccaaattt
    12661 acaaaagcga ctcatagaat tatttcctcc cgttaaataa tagataacta ttaaaaatag
    12721 acaatacttg ctcataagta acggtactta aattgtttac tttggcgtgt ttcattgctt
    12781 gatgaaactg atttttagta aacagttgac gatattctcg attgacccat tttgaaacaa
    12841 agtacgtata tagcttccaa tatttatctg gaacatctgt ggtatggcgg gtaagtttta
    12901 ttaagacact gtttactttt ggtttaggat gaaagcattc cgctggcagc ttaagcaatt
    12961 gctgaatcga gacttgagtg tgcaagagca accctagtgt tcggtgaata tccaaggtac
    13021 gcttgtagaa tccttcttca acaatcagat agatgtcaga cgcatggctt tcaaaaacca
    13081 cttttttaat aatttgtgtg cttaaatggt aaggaatatt cccaacaatt ttatacctct
    13141 gtttgttagg gaattgaaac tgtagaatat cttggtgaat taaagtgaca cgagtgttca
    13201 gttttaattt ttctgacgat aagttgaata gatgactgtc taattcaata gacgttacct
    13261 gtttacttat tttagccagt ttcgtcgtta aatgcccttt acctgttcca atttcgtaaa
    13321 cggtatcggt ttcttttaaa ttcaattgtt ttattatttg gttgagtact ttttcactcg
    13381 ttaaaaagtt ttgagaatat tttatatttt tgttcatgta atcactcctg aagtgattac
    13441 atctataaat aaatacagaa gttaaacgat ttgtttgtaa ttttagttat ctgtttaaaa
    13501 agtcataaga ttagtcactg gtaggaatta atctaacgta tttatttatc tgcgtaatca
    13561 ctgtttttag tctgtttcaa aacggtagat gttttatcta cattacgcat ttggaatacc
    13621 aacatgacga atccctcctt cttaattaca aatttttagc atctaattta acttcaattc
    13681 ctattataca aaattt
//
LOCUS       DBBGSP010000076        13678 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000076 DBBGSP010000000
VERSION     DBBGSP010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13678
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.076"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..902)
                     /locus_tag="ACIZE9_002629"
     CDS             complement(<1..902)
                     /locus_tag="ACIZE9_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HGC6094442.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSE"
     regulatory      complement(926..970)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1185..2153
                     /locus_tag="ACIZE9_002630"
     CDS             1185..2153
                     /locus_tag="ACIZE9_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6094443.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2266..2544
                     /locus_tag="ACIZE9_002631"
     CDS             2266..2544
                     /locus_tag="ACIZE9_002631"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6094444.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2662..2898
                     /gene="secG"
                     /locus_tag="ACIZE9_002632"
     CDS             2662..2898
                     /gene="secG"
                     /locus_tag="ACIZE9_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGC6094445.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3001..3756
                     /locus_tag="ACIZE9_002633"
     CDS             3001..3756
                     /locus_tag="ACIZE9_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC6094446.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3759..6116
                     /gene="rnr"
                     /locus_tag="ACIZE9_002634"
     CDS             3759..6116
                     /gene="rnr"
                     /locus_tag="ACIZE9_002634"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGC6094447.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6138..6602
                     /gene="smpB"
                     /locus_tag="ACIZE9_002635"
     CDS             6138..6602
                     /gene="smpB"
                     /locus_tag="ACIZE9_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGC6094448.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6904..7623
                     /gene="atpB"
                     /locus_tag="ACIZE9_002636"
     CDS             6904..7623
                     /gene="atpB"
                     /locus_tag="ACIZE9_002636"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGC6094449.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7676..7891
                     /gene="atpE"
                     /locus_tag="ACIZE9_002637"
     CDS             7676..7891
                     /gene="atpE"
                     /locus_tag="ACIZE9_002637"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HGC6094450.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7982..8506
                     /gene="atpF"
                     /locus_tag="ACIZE9_002638"
     CDS             7982..8506
                     /gene="atpF"
                     /locus_tag="ACIZE9_002638"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGC6094451.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8493..9035
                     /locus_tag="ACIZE9_002639"
     CDS             8493..9035
                     /locus_tag="ACIZE9_002639"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGC6094452.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9058..10614
                     /gene="atpA"
                     /locus_tag="ACIZE9_002640"
     CDS             9058..10614
                     /gene="atpA"
                     /locus_tag="ACIZE9_002640"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGC6094453.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            10628..11530
                     /locus_tag="ACIZE9_002641"
     CDS             10628..11530
                     /locus_tag="ACIZE9_002641"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGC6094454.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRAVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11553..12959
                     /gene="atpD"
                     /locus_tag="ACIZE9_002642"
     CDS             11553..12959
                     /gene="atpD"
                     /locus_tag="ACIZE9_002642"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGC6094455.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12973..13395
                     /locus_tag="ACIZE9_002643"
     CDS             12973..13395
                     /locus_tag="ACIZE9_002643"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGC6094456.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4521 a         2448 c         2980 g         3729 t
ORIGIN      
        1 ctttcggaaa aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc
       61 caaaattcat aacgatcaac caatgtttgt ccacgactta ttccctgagt ttccacagcg
      121 gtgaagcttt tgaaaccttc acagatggcc ccctcgatga aataagcaac agctaacgga
      181 tcattgatga cacatcctaa aattctttct tgtttccagt ggaagtcaaa ataaaaacga
      241 gtgatcgctt ttaaatactc tccctcttca ggattcattt gacagcagta ttcgaggata
      301 gtcggtgtca agacgatttc tcttgtcaca tctaacccaa ccatttctat cgtttgtttg
      361 agattctcga atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact
      421 ggcgaacagt taccatggct tttgtaagtt ccacccatcg agacaaaacg atccatatgt
      481 ttcccaatat ttgggttgac tttcaaagca aaagcgatat tggtcaaagg acccaaagca
      541 atgactgatg tatttgtctt ttctttgaaa taatcagcca aaaaatcaac ggcatggaga
      601 ggttctgcct gttttctcaa gatcatcggg aaatttgttt cccctaaacc atccatacca
      661 tgagtgtctt gtgcactgat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca
      721 ggaatgtcta aacgatcaca gcgttccagg catttcagca cattctgcgt acctatatct
      781 gcagggacat tcccacaaac tacggtaata gcaactactt cgatatcagg ggatttgaca
      841 gctaatgata aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tacttttcgc
      901 attatttcca atctcctttc tttagagata cttagttttt tattctggga agtttccgaa
      961 ccagtccaag acgagcgtct tgattataat gcacgaaatt agtatactgg cttttattgc
     1021 gaatgtaaat gctctcttac aagtaaatct attgaggaga actttaagta aatgatacaa
     1081 tgaaaaagaa atggaattta cgtgtgccga aaataaagaa tcctatggat cggtacattg
     1141 gataatagat agattatagt ttggcagaaa gcggcgggtg tacaatggtt attttttatt
     1201 tcattcttat tctgataatt atagggatca gttaccattt tctttcttat ttttatgcaa
     1261 agaaattagt aagagcggga gtacagagag gatatgactg gtatgaagac actggtcatc
     1321 gtttgatgga ccctgctgca gtcacgtcag tagaaaaaaa acgacaaaaa ttagaagaag
     1381 agtgtgaaag cttttgggag cagggaacac ccaaaacaat caaaagttat gacgggttga
     1441 aactagctgg tcagatgttc atccatccaa ataagcagaa taaatgggtc atttgcgtac
     1501 atgattaccg aagcacaggg aaaagagaca tgtctcatat aggtaaaaga tatgcagaga
     1561 aaggattcaa cgttcttgta cctgatttac gtgcgcacgg agaaagtgaa ggagaaatca
     1621 tcggaatggg atggctagat cggctagatt taattgcctg gatccaactc atcttagatg
     1681 aacagccgaa tgcgtccatt attttacacg gcggatcaat gggagcttct acgatcatga
     1741 tggcaagtgg tgaaaaactt ccatcagcgg tcaaaggatt tattttagac agcggatatg
     1801 tttctgttta tgcagaattc cgatatatgt taagtaaaat cactgtcttt cctaaaaaaa
     1861 tggtcatgag atatgcgaat cattatgccc agaaatacgc cggttactcc ttaaagcaag
     1921 catcagctac gagacagctt ggcagcaacc atctgccttt attagtcatc catggtgaaa
     1981 gagatcattt tgtccctaca gaagcagcgt acacgattca aaatgctacg gcaggggata
     2041 aagcactgct gcttgttcca gaagcagaac acttggaagc atcgatgaaa gatccgaaaa
     2101 cctattggac agtgattttt tcatttattg aacaaagaat aacgatggat taattttctc
     2161 ttcttttttg taagtaattc gaggataaat aattgtttat agatctggag actgctaaaa
     2221 taaggtagga ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagaa
     2281 gaaaaaaatc gtcttgcttt attcaatgat gagcaacaag agattggaga aatgacatgg
     2341 tcagatgcgg gcccagacat catgatcatt gaccatacat ttgtagatcc agcatatcgt
     2401 ggtcaaaagt tagctgaaaa gctagtgtat actggagtag aattagcaag acgagacggg
     2461 aaaaagatca ttcctttatg cccttatgca aaaaaagagt ttgaaaagaa accagaatat
     2521 caagacgtct tacgtcagtc ataagaataa cagctgaaag ttttgaactt tcagctgtta
     2581 ttccatttat atagagttgt cacggacttt tatctatgat aaagttaaag agacgatatc
     2641 ttttgggaag gaggctgcga tatgtataat ttaattttgg gaatcgtgat cgttttatcg
     2701 attgttatgg tcattgcgat tatgatgcag ccaagcaagc aaaatagtgc agcgagtgca
     2761 tttaccggcg gtgcggatca actattcggc aaacaaaaag ctcgcggctt tgaagctgtc
     2821 atgcagcgat caactgcagt tatgggagct atctggatga tcttattatt tgtcctagca
     2881 tatttatctt cgaagtagtt gaataagcct ctcgcaaaac ggcgggcggc tttttttatt
     2941 gcaaagagaa cgcttaagaa gaagttatga aagaaactat ggtaaaatga ggcgaaagag
     3001 gtgagacgag tgagacaatt accaaaaccc ctttatgcaa aacatggaaa gcgagcggtt
     3061 ttgctgcttc acgcttactc aggaagtcca aacgatgttc gaatgctcgc acgatttttg
     3121 gaaaaagcag attatacagt ttatgcgccg ctttttaaag gacacggaac aatggagcca
     3181 tatgatatct tgcaagaaaa agcagaaagc tggtgggcag acactaaaaa agccatccat
     3241 tttttacagt ctgagcagtt ttctgatatt gccgtattag gattatcaat gggcggcatc
     3301 tttgctgtac gagcactaga agaagaatca gtgattggcg gcggtttttt ctgttcgcct
     3361 ttgtctcctg taaaaacaaa cgtgcctgaa aactttgaaa aatacgtacg tcaagtgctg
     3421 aagacagcag gtaaatcaga gaaagaaatc aatgaaaaag cagttgctta ccgctcgtta
     3481 gctgaacaac aattaatgga tatacaagat caggcagcaa tcgtagaaag taggttgtca
     3541 gatatccaac agccgatatt tttagctcaa gctgggaaag atgaaatgat cgaccctaat
     3601 ggcgtatttg aaactgcacg caagttgagc cgtcagcgag tgacacttca atggtatcct
     3661 gaaagtggtc atgtgattac agttggtaca gcaagacgcg aattagaaaa agacgtcttg
     3721 gaatttttag aaaaattacc ttggaatgag gaataaatat gacaaaagaa acgataaaag
     3781 agaaaattct ctttttcatg gaaagcagtc gcaaacgcag tttttctatg gaagaaatcg
     3841 ctgaaggttt agggttccaa aaaagcgatg attttaaatt actagtacaa acgattgctc
     3901 aaatggaaag agaacagagt atagttttca ataaaaaagg aaaagtgaaa cttcctttaa
     3961 aaccaatctt gatcgaagga acatttcgag caaatgaacg aggatttgga tttgtaacga
     4021 ttgatcccga agaagatgac atctatatcc caaaagaagc gactggtttt gcaatggatg
     4081 gagacaccgt agcaatcgat atcatgaagc gagcaaatac agatatggat cgcggagcag
     4141 aggggaaagt agtcgagatt cgagaccggg cgactactca gttagcaggg gaattcgttg
     4201 cttattcaga agaagaaata caagaaacag atctttacgg cgttgttatc ccgaaagata
     4261 gaaagctcaa ccaatttaaa gtatatgcag cagcagaggg agttcgtcca gttgacggaa
     4321 gtattgtgct gatcgaactg acccattacc ctgaaaaagg gtatgcgact agtttagaag
     4381 ggataatcaa gcaagtgatt ggtcataaga atgaccctgg catggatatc ctctcaattg
     4441 tcgtggctaa tggtatccct acgaaatttc ctgatgatgt attgtctgaa gcagatgaag
     4501 ttccagatca aatcagcgaa aaggatataa ctggacgtag agatttaaga aatcagctca
     4561 ttgttacgat tgatggagaa gatgcaaaag atctagatga tgcagttacg gttaaaaaat
     4621 tagataacgg taattatttt cttggagtac acattgcaga tgtttcttac tatgtgacac
     4681 aaggcagtca attggacaga gaagcatatg aaagagggac aagtgtatat ttgactgatc
     4741 gagtgattcc gatgatcccg caacgtttat cgaatggtat ctgttcactg aatccccatg
     4801 ttccaaggct gaccatgagt tgcgaaatgg agattgatcc aaatggacaa gtagtctctc
     4861 atgatatttt cccaagtgtg atccaaacaa cagaacggat gacctacaca gctgtcaatc
     4921 aaatcttaga agatcaagac gaagaaacga tgcaacgcta tgctcagctc gtacctatgt
     4981 tccaagaaat gggtgaattg catcgaatcc ttgaaacgat gcgaatcaaa cgtggcgcga
     5041 tttcttttga ggatcgcgaa gcgaaaatcc ttgttgatgc tgaaggacac ccaaatgaca
     5101 tccagctaag aagcagagga attggtgaac gcttgatcga atctttcatg cttgcggcca
     5161 atgaaacggt agctgaacat tataataaat taaatctgcc gtttatttac cgaatccatg
     5221 aacagccaaa agaagaaaaa atgcagcgct tctttgattt tgcttcagct ttgggcattc
     5281 tggtccgagg aacgaaagga acgatcacac caaaagattt acagcatgtg atcgaaggag
     5341 tagaagacaa accagaagct gcagttatca atactatgtt gctaagaagc atgcaacaag
     5401 cacgctattc agaagacaat tttgggcatt atggcttagc ggcagattac tacacacact
     5461 ttacatctcc tattcgacgc tatcccgatc taatcgtcca tcgtctgatc cgttcttaca
     5521 gtgaagataa aagtgaaagc aatcaaagtt cgtgggctgc ggaacttcct gaaattgcag
     5581 atcatagttc taagatggaa cgtcgtgcag tagaaacaga acgtgaagta gattccatga
     5641 agaaagcaga attcatgatg gacaaagtgg gagaagaatt cgatgggatc atcagctctg
     5701 ttgtgaaatt cggcctgttt atcgaactgc cgaatacagt agaaggattg atccatatca
     5761 atgaattgaa acaggactac ttccattttg ttgaaaatca tttagctctt gtaggtgaaa
     5821 gaactggtct gacttttaaa atcggacaaa aagtgcgcgt aaaagtagtc aaagctgatc
     5881 cagatgaacg agcagtggat tttgaactcg tttccgcaga agaggtcact gcgttggaac
     5941 gtccaaaagc acgcaatgga aaatctggaa aacgagaagg aaaacaagca ggcaaacgct
     6001 cagaaaaaaa tggcaagaag aacaaacgat atagtgatag taagcaaacg ttcggtaaga
     6061 aaaaagggaa aaagccattt tacaaagatg tcaaaaagaa gaaaaagaaa aaataaaatg
     6121 agttggagga aacagctatg ccaaaaggcg agggaaaact aattgcacaa aacaagaaag
     6181 ctcgccatga ttattcgatc atcgacacga tggaagcagg gatggtcttg caaggaacgg
     6241 agatcaagtc gatacgaaac agccggatca atctgaaaga tggatttatt cgcgtccgca
     6301 acggggaagc tttcttgcat aatgttcata tcagtcctta tgaacaagga aatattttta
     6361 atcatgatcc gttgcgcacg agaaagttat tattacacaa gaaacaaatc gttcgtcttg
     6421 aaaacgaatt gaaaaacact ggaatcactg ttgttccttt aaaagtctat attcgtaacg
     6481 gctatgccaa ggtattgatt ggtctggcaa aagggaaaaa atcgtatgat aaacgggaag
     6541 atttgaaacg aaaagatatc gatcgacaaa ttgatcgaac attaaaaaat ttctctagat
     6601 aatttcatta tcctttttcg catattcggt gcttttgctt ttacttaatg ataaaatttg
     6661 ttagcattta atctgataaa acatgattat cacaggtttt ttcttagatc aggagcaccg
     6721 tgcatgggga aaaattcgct tcgtttttga ctgaaataaa aaagtgtcta attttcatga
     6781 aaatgttttg aattttctgt ttcatggtgg tatgataccg tgtggttaga aaccgattgg
     6841 aaaaaaccag atacgcacat gaattgattt tatgtgaatt tcggggaaaa gaggtgaaat
     6901 ggattggatg aacgctcgct aacgtttcac attggaccaa tttggtttga tggtacagtt
     6961 tgtataatgg tgttactgac ctgtttgatt gttttcttct tagcttactt ttttacaaga
     7021 aatcttaagt tgaaaccaac aggcaaacaa aatgcgatag aatgggtcat tgattttagt
     7081 cgaggaatcg taacagataa tctgcctaga aaagaattga gcaatttcca tttgttggca
     7141 tttacattgt ttttatttgt ttttgttgca aacaacatag gtttagtaac aaaaatcgtc
     7201 ttacctaacg aaacaacact ttggaaaagc ccgacagcag acccgtttgt tactttaact
     7261 ttggcattta taatgatctt acttactcac ttattcgggg tgaaaaagtt aggcttcaaa
     7321 ggatatttcg taaattcgtt cttgaaaccc tatagtttta tgtttccgat gaaactgatt
     7381 gaagaattta caaatttatt aacacttgct ttacgtcttt atgggaatat ttatgcgggg
     7441 gaagttttgc taaccttgat tgcaaaaatg atgacaagct taggctggtt ctcattacca
     7501 ttagcaattc cattagagat ggtctggatc gcgttctcct tgtttattgg gagcatccaa
     7561 gcatttgtct ttgtcacttt gtcaatggtt tatatgagcc ataagattga agtagaagaa
     7621 taatactcgg ttaaaaaaca aactactatt tatctatttt aggaggaaaa caattatgaa
     7681 ttatatcgca gcagcaatcg caatcatggg agcagcaatc ggagccggtt atggtaacgg
     7741 tcaagttatc tctaaaacaa tcgaatcaat ggctcgccaa cctgaaatgt ctggtcaatt
     7801 ccgtacaaca atgtttatcg gggtagctct agttgaagct gttcctatct taggggtagt
     7861 tatcgccttg attctagttt ttgccgttta attgaatcag tattaaggca gaaacaacat
     7921 cgtttgttac tgctttttta catggaaact agaaatactc caaagaaagg aaggctcgcc
     7981 tatgctgaat caattggcaa ttgcagaagt tggcaatgcg atgttaggta atatcatcgt
     8041 tgtcagcggc tcatttttga tactactggc tctcttgaag cactttgctt ggggaccaat
     8101 cagcgatatt ttgaaaaaac gtgaagacaa gatcgccaat gatttagatt ctgcagaaca
     8161 atctcgcatc aactcagcga aaatggaaca agaacgcgaa caacaattgt tagcctctcg
     8221 ttctgatgca gctgatatca tcaaaaatgc gaaagaaagt ggagaattaa gccgccaaaa
     8281 tattttgaag gatgctcaag aagaagcagc tcgtctaaaa agcaaagccc aagctgatat
     8341 cactgtagaa cgtgattcag cgctgaactc tgtaaaagac gacgttgcag aactctctct
     8401 tcaaatcgcg gaaaaaatct tgaacaaaga attatctcca gaaatgcatg aatcattaat
     8461 caatcaatac attgaaggtc taggttcttc aaatgaaact agataaatat acagtaggaa
     8521 gacgttacgg gaaagcttta tttgaactgg cgatcgattc aaatcaagca gaagaaatct
     8581 atcaagatct cgtaagttta cgtcaaatct atgaacaagt acctggatta gggaatatgt
     8641 taagtgatgt tcgtctagaa cctcatgaaa aacgagaaat catggacaag cttgtcagcg
     8701 gttatgatgg gatcgttaaa aactttttag aagttgttta tgagtataac cgaatggatg
     8761 accttttgtt catgatcgaa gaatatgaac gtcgatatga tgaacatcaa gggttactat
     8821 tgggaagtgt cacaacagca gtcccacttt cagacgaaca acgaatacaa ttagaaaaga
     8881 atgttgcaaa aacaatggac tatcaatcag ttgaattaaa acaaatcgtt gattcttcta
     8941 ttattggtgg cgcgattgtt gaagccaacc atcgagtaat cgacggaagc attcgcacgc
     9001 aattagaaaa aatgcgtaat caattaaaca gatagtacaa agaggtaggt gaatcgaatg
     9061 gccatcaaag cagaagaaat tagtgccttg attaaagaac aaattgaaaa ttatcaaaac
     9121 gtgctttcag tcgaagaaat cggtaccgta acttatgtag gtgacgggat cgctcgtgca
     9181 catggtttag aaaacgcgat gagtggtgag ttgcttgaat tttcaaacgg ctcatacgga
     9241 atggcgcaaa acttagagtc aaatgatgta ggtatcatta tccttggcga tttcgagtcc
     9301 attcgtgaag gagataaagt aaaacgaaca ggtaagatca tggaagttcc agttggagag
     9361 gccttgatcg gtcgggtagt caatccgcta ggtcaaccaa tcgacggact aggtgaaatc
     9421 gttactgaca aagctcgtcc agtagaagcg atggcaccag gtgttatgca acgtaaatct
     9481 gttaacgaac caatgcaaac agggctaaaa gcgatcgacg cccttgtgcc aatcggacgc
     9541 ggacaacgtg aattagtcat cggtgaccgt aaaacaggga aaacttctat tgcgatcgat
     9601 acgatcatca accaaaaagg tcaagatatg atctgtatct atgtagcaat cggacaaaaa
     9661 gattctacag ttcgtacaca agttgaaaca ttgaaaaaat atggcgcaat ggattacaca
     9721 atcgttgtga atgccggtgc gtctcaacca gcaccattgc tttatatcgc accatatgct
     9781 ggtactgcaa tgggtgaaga attcatgtac aacggtaaac atgtattgat catttttgat
     9841 gatctttcaa aacaagctgt tgcttatcgt gaactttcct tgctacttcg ccgtccacca
     9901 ggtcgtgaag cttatcctgg ggatgttttc tacttgcact cacgtttatt agaacgtgca
     9961 gcaaaattaa gtgatgattt aggtggcggt tcaatgactg ccttaccatt tgttgaaaca
    10021 caagctggag atatctctgc ttatatccca acaaacgtta tttcgatcac tgatggacaa
    10081 atcttcttag aaagcgactt gttctacgca ggtactcgtc cagcggttga tgccggacta
    10141 tctgtatctc gtgtaggggg ttctgcgcaa atcaaagcaa tgaaaaaagt tgctgggact
    10201 ttacgcctag acttagcaag ttaccgtgaa ttagaagcat ttacacaatt cggttctgac
    10261 ttggatgcag caacacaagc aaaactaaat cgtggacgcc gtacagtaga aatcttgaaa
    10321 caaaaattgc atgcaccgct agctgttgaa aaacaagtag tgattttgta tgctttgaca
    10381 catggattct tagatagtat ccctgtagac agtattttag acttcgaaca tgaattattc
    10441 gaatatctgg ataccaatca ttcagatatc tttgaaacaa tccgtacaac aaaagatctt
    10501 ccagaagaag aagcgttgaa cagtgcgatt caggaatata aagacatgtt cttagctaca
    10561 aaaggaagta attcctctac agaagataaa ttgaaatcca ttcaaaatgc atagtgaggt
    10621 gagatgaatg ggtgcttcat taaatgaaat caagacacgt atcgcttcaa cgaaaaaaac
    10681 gagccaaatc acgcgggcaa tgcagatggt gtctgcttct aagttgacaa aatctgaagc
    10741 ttcttcacag aagtttcagg tttatgcaac aaaagtaaga gaaatcgtta cgcatttgac
    10801 tgctactcag ttaaatgata ttgcctcaga aaatcctaga ggggatatca attacaacag
    10861 catgctgctc agccgtgctg tgaagaaaac tggttatatc gtcatcactg cagatggcgg
    10921 tttagtcggt ggatataaca gctcgatatt gaaacaaacg atgtctattt tagaagaaga
    10981 ccaccaatca cccgatgatt acgtgatgat cgcaattggc ggaactggtg cagacttctt
    11041 taaagcacgc ggtatcaatc tagcatatga gctgcgcaat ctatctgatc agccaagctt
    11101 tgatgaagtc cgcaaaatcg taaatatggc aacaactatg ttccaaaacg aagtattcga
    11161 tgaattatac gtatgttata accatcatat caattcgcta actagtcagt ttcgtgtaga
    11221 aaaaatgctg ccaatctcag acttagatcc agaagaagca acgactttcg aacaagaata
    11281 tatttttgaa ccttcaaaag aagaaatctt gtctcagtta ttgcctcagt atgctgaaag
    11341 tttgatctac ggtgcgatcg ttgacgccaa aacagcagaa catgctgctg gtatgacagc
    11401 aatgaaaaca gcaactgata atgctgctaa tatcattgat gagctgacgg tttcttataa
    11461 ccgtgcaaga caaggggcta ttacccaaga aattaccgaa attgttgccg gagcttcggc
    11521 actagaatag tattgagatt ggaggaaaaa agatgagttc aggcaagatt gttcaagtaa
    11581 tcggtcccgt tgtcgacgtg gaattttctt tagaccaatc cttaccagat atcaacaacg
    11641 cattagttgt ttataaaaat gacgaaaata aatcaaaagt tgttcttgaa gcagcgttag
    11701 aattagggga cggagtgatc cggaccattg cgatggaatc aacagatggt ttacaaagag
    11761 gaatggaagt cattgataca ggcaaagcaa tctctgttcc tgtaggtaaa gaaacattag
    11821 gtcgcgtatt caacgtacta ggagatacga tcgatttaga aacacctttc ccagaagatg
    11881 cggaaagaag cgaaattcat aaaaaagcac cagcctttga cgaattaagt acaagtacag
    11941 aaattttgga aacagggatc aaagttatcg atttgcttgc cccatattta aaaggtggga
    12001 aagtcggact attcggtggt gccggtgttg gtaaaaccgt actgatccaa gaactgatcc
    12061 ataatatcgc ccaagaacat ggtggtattt ctgtatttac cggtgtaggt gaacgtactc
    12121 gtgaaggtaa tgacttgtat tatgaaatga aagattcagg agttatcgaa aaaacagcca
    12181 tggtgttcgg acaaatgaac gaaccaccag gtgcacgtat gcgtgttgct ttgactggtt
    12241 tgacgattgc ggaatatttc cgtgatgtag aaggtcaaga tgtactgttg tttatcgaca
    12301 acattttccg tttcactcaa gctggatctg aagtatcagc cttgttagga cggatgcctt
    12361 ctgcggttgg ttatcaacca acattggcaa cagaaatggg tcaattacaa gaacgtatca
    12421 catctacgaa aaaaggttcg atcacatcga tccaagcaat ctatgtgcca gccgatgact
    12481 acactgaccc ggcgccggca acagcattcg cccatttgga tgcgacaacc aacttggaac
    12541 gtaaattaac agaacaaggg atttatccag cggtagatcc attggcttct tcttcaagtg
    12601 ctttagcacc tgaaatcgtg ggggaagaac attataaagt agcaacagaa gtccaacacg
    12661 tattgcaacg atatcgtgaa ttacaagata tcattgctat cttaggtatg gatgaattat
    12721 ccgatcaaga aaaagtgtta gtttctcgtg cccgcagagt ccaattcttc ttgtcacaaa
    12781 actttaacgt ggctgaacaa tttactggtc ttccaggttc atatgtccct gtagaagaaa
    12841 cagtgaaagg attccgcgaa atcttggaag gcaaatacga tgatcttcct gaagaagctt
    12901 tccgaagtgt tggccgaatc gaagacgtcg tagaaaaagc gaaaacacta ggctactaga
    12961 aaggggtgcc ccatggatca atatttaaca gtaaatgtgg taactcctgc cggtttggtc
    13021 tatgatcacc atgcagctat cgtcgttgca cgtacgacag ctggtgagct tgggattttg
    13081 cctaaacatg caccaatcat cgttccattg acgattgatg aagttcgtgt aaaacgaaca
    13141 gattcagata cccacgtcga ttggatcgct gttaatggcg gaatcatgga agttcgtgat
    13201 aatgttgttt caatcgttgc tgatagtgcg gaacgtgaac gtgatatcga tgtatctcgt
    13261 gcggaacgtg caaaacaacg cgcagaacgc caaatcgaag aagcaaaagc aaaacaagat
    13321 acgaacgaat tgaaacgggc aactgttgcg ttgcaccgag caatcaatcg tatcaaagta
    13381 tctaagcact cataaaatga gatgcggatg tttatccgtg tttaagaaca gtaaaaagag
    13441 gttatgacag aagtggtcag cttcaagaca taagaaggaa tttacgaaaa ttgcttctca
    13501 aatttttgtg aaatctcagc ttatttttcg aagaagctac ttctggaaca ccgtatatca
    13561 gaggttgtaa aatcagcgtt ttgtcctgag tattagagaa acaaatggaa aatagttcct
    13621 catattttgc cgttttttga gctaataccg agggtcagat gattgaacac cgtttatt
//
LOCUS       DBBGSP010000077        13145 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000077 DBBGSP010000000
VERSION     DBBGSP010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.077"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(77..149)
                     /locus_tag="ACIZE9_002644"
     tRNA            complement(77..149)
                     /locus_tag="ACIZE9_002644"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="ACIZE9_002645"
     CDS             530..1099
                     /locus_tag="ACIZE9_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGC6094457.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="ACIZE9_002646"
     CDS             1086..1946
                     /locus_tag="ACIZE9_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGC6094458.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /gene="yycF"
                     /locus_tag="ACIZE9_002647"
     CDS             2136..2840
                     /gene="yycF"
                     /locus_tag="ACIZE9_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGC6094459.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="ACIZE9_002648"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="ACIZE9_002648"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HGC6094460.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /gene="yycH"
                     /locus_tag="ACIZE9_002649"
     CDS             4677..5993
                     /gene="yycH"
                     /locus_tag="ACIZE9_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HGC6094461.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="ACIZE9_002650"
     CDS             5994..6863
                     /locus_tag="ACIZE9_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HGC6094462.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="ACIZE9_002651"
     CDS             6918..7727
                     /locus_tag="ACIZE9_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGC6094463.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="ACIZE9_002652"
     CDS             complement(7830..8459)
                     /locus_tag="ACIZE9_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGC6094464.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="ACIZE9_002653"
     CDS             8629..9921
                     /locus_tag="ACIZE9_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6094465.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="ACIZE9_002654"
     CDS             complement(9997..10659)
                     /locus_tag="ACIZE9_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGC6094466.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="ACIZE9_002655"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="ACIZE9_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGC6094467.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="ACIZE9_002656"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="ACIZE9_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGC6094468.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4369 a         2264 c         2833 g         3679 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tttgtgtgta
    13081 attataatga aaatagttat ttttaatagt tataatattt tatctattaa aagtaaatat
    13141 ccatt
//
LOCUS       DBBGSP010000078        12735 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000078 DBBGSP010000000
VERSION     DBBGSP010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.078"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            94..537
                     /locus_tag="ACIZE9_002657"
     CDS             94..537
                     /locus_tag="ACIZE9_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGC6094469.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(543..1727)
                     /locus_tag="ACIZE9_002658"
     CDS             complement(543..1727)
                     /locus_tag="ACIZE9_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HGC6094470.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            1995..2693
                     /locus_tag="ACIZE9_002659"
     CDS             1995..2693
                     /locus_tag="ACIZE9_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGC6094471.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2700..3377
                     /gene="nth"
                     /locus_tag="ACIZE9_002660"
     CDS             2700..3377
                     /gene="nth"
                     /locus_tag="ACIZE9_002660"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGC6094472.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3503..4036)
                     /locus_tag="ACIZE9_002661"
     CDS             complement(3503..4036)
                     /locus_tag="ACIZE9_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094473.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4333..6714)
                     /locus_tag="ACIZE9_002662"
     CDS             complement(4333..6714)
                     /locus_tag="ACIZE9_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HGC6094474.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6704..7351)
                     /gene="recU"
                     /locus_tag="ACIZE9_002663"
     CDS             complement(6704..7351)
                     /gene="recU"
                     /locus_tag="ACIZE9_002663"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGC6094475.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7415..7954
                     /locus_tag="ACIZE9_002664"
     CDS             7415..7954
                     /locus_tag="ACIZE9_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGC6094476.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8044..8463
                     /gene="gpsB"
                     /locus_tag="ACIZE9_002665"
     CDS             8044..8463
                     /gene="gpsB"
                     /locus_tag="ACIZE9_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGC6094477.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8485..8852
                     /gene="rnpB"
                     /locus_tag="ACIZE9_002666"
     ncRNA           8485..8852
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACIZE9_002666"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9061..10227
                     /locus_tag="ACIZE9_002667"
     CDS             9061..10227
                     /locus_tag="ACIZE9_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGC6094478.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10273..11769
                     /locus_tag="ACIZE9_002668"
     CDS             10273..11769
                     /locus_tag="ACIZE9_002668"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HGC6094479.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEYRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11850..12533
                     /locus_tag="ACIZE9_002669"
     CDS             11850..12533
                     /locus_tag="ACIZE9_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGC6094480.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            12542..>12735
                     /locus_tag="ACIZE9_002670"
     CDS             12542..>12735
                     /locus_tag="ACIZE9_002670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094481.1"
                     /translation="MTEVVSSKIFRIIFRKSYFWNTVYQEVVSLPFSSESQGTISKNS
                     FSCLMNIVTCDSELAGEHRL"
BASE COUNT         4273 a         2228 c         2630 g         3604 t
ORIGIN      
        1 tggtttcaga ttgggttttc ctacaaaata tttttatctt tgttgaatag gaaacaaaaa
       61 aacaatataa tgaaagaaaa agaaggtgta gaaatggata aaagacaact gctaatagaa
      121 gaatatctgg atttagctaa tgagattatt catcgtaata aaccagaaat ggaaaaagaa
      181 tttgcaggat ttactctaaa tgaactagaa gtgattgaac atatcgggaa aatccctgat
      241 cctaacgtga caaaattagc gaatgctagt tacatgacta gaggagccat cagtaagcta
      301 acaaaaaaac tgatagctag agggatcata aacacttatc aaagcgaaga gaataaaaaa
      361 gaaatctatt ttcaattgac gccaatcgga caaaaaataa ggaatagaca cgagcaactc
      421 catcaaaaat gggtacagcg agatgctact gtatttgaaa atatgtcaaa agaagaattt
      481 gacacagtat ttcgttttat cggtcgatac agagaattta tacgaagtag caaatgaagc
      541 tactattttt tattgtagtg ataataggca aaaatcataa gcaaaaatcc gaataccgtc
      601 ggaagaaatg gtgctgcagc ataaagctgt cctgcgatta gcgggccgat gacgcgcgat
      661 agagattgta tactttgggt accgcccatt acaagacctt gctggttatc tgagacagaa
      721 ttggatagtt ggccattgaa tacaggagta aaaatagaat caccgaaacc ataacagata
      781 atcccaaata aaaacaaaat cggcagtaga agaattccag ataatgtgat gaatagatag
      841 gcgaggattt cactgaacat ccctattctt gtgatctgct gttctgaaaa ttttttgagc
      901 aatcgaggca taatgaacaa ttgcgagaca gtatccaaga ttccaatcaa agagaagctt
      961 aaaccaacca acccagcctt ccactgaaag gcgtcaatcg aaaattgaga aaagatagat
     1021 tgaagagagc cagctgccaa ccaaacagca aaacctgctg tcaataaagg aataacggat
     1081 gaaatcttga ataattgttg taattggtga aaaggtctta catgggagaa acttaaatct
     1141 actgaacgtt tttttattgg aaggctttct agcataaatg tgtagccata aacggcattt
     1201 aagaaagtaa agagtgctcc aataaatata ggaacagaat tccccaactc agctaataga
     1261 ccccctataa taggacccag cgttgttcct ataccgacta aagcacccat ccatccaaaa
     1321 actttggttc tttcattagg ttccgtgatg tcggcaaagt aagcatataa ggtggagatt
     1381 tctcctgccg tcaatccttc aatgatacga ccaaggaaca acatccatat cgaatttcct
     1441 aaaccaaaaa gcaaatatcc gatacttgat cctaataaac tgataataag gatcggatga
     1501 cgcccaaaat gatcacttaa gctaccgaga atgggggcag ataagaaggc agctagagca
     1561 taaacagaca tgagcaaagt gatatagaaa gcttgctgat gtatggagtg agaataaggc
     1621 agcgttaaaa acggaagtac aggactgacg atagtaaatc ctaatccagt gaataagaca
     1681 gagacgtatc caaaaacttt agaatgttta tttgtgaaac tgtacatgta aaaactcctt
     1741 tatgcaataa tgttaacttg gaaacaaaaa tagtgtatag taattttgtt tccttgtcaa
     1801 cattctaagg aacagcgaaa tctacttaat ttatttattc cgaaaagtga agatacgcat
     1861 caaaaacatg aacaaacaaa aatcaagtag acgacattgt aaatctgacc gatcagtgaa
     1921 gtaaatagaa aagaaacctg ttcttgcttc ccatgttttt tttacgtata ctgtgattga
     1981 gcggaggaga aatcatgttg aatttagaaa attacttaag cgctggacaa acagtcatat
     2041 ctaatctttt acttaaaaat tatcatagga tcggtctaca atctgaagaa tttttatttg
     2101 ttctacagtt gcatatggca cagcttgaag gagatacttt ccctgatttg cagatgattg
     2161 ctatggatat gggaatcaaa caagatcaga tttttcaaat actggatcgt ctcgtaacaa
     2221 atggatttat caagatagaa acgacgattg tcaacggtaa aaaagcagat cgatataatc
     2281 tttaccccat ctatgatcta ttaggtgagt atttaaaaac acaagaaaaa aaatacgaag
     2341 aaaaaacaca agaaaaagaa atccagtcag tgtatcaatt atttgaacaa gaatttggac
     2401 gcccgctttc ttcgatcgag ttccagcgga tcggacaatg gctagaagaa gaccattatc
     2461 agccggaaat tttgaagcta gcactgcggg aagccgtatt aaatcaggct tatagtttta
     2521 attacgttga ccgcattttg ctatcgtggg aaagaaaaaa tctacgtaca aaacaacaag
     2581 tggaagaaga ccaaaaacga agaaaacagc agcttcttca aagagaagta gaacagtcag
     2641 ctcaacaaga agaattgccg aaagtctcac tgaaaaattg gttggaggag tagcggaata
     2701 tgttaagcaa acaaaaaaca atggaagctc tagaaacgat gtatggaatg tttcccgaag
     2761 cacatggaga actcaagcac aataatccat ttgagttatt gattgcagtg atcttaagtg
     2821 cccaggcgac agatgtatca gtgaataaag caacgccaga tttgtttgcc tcttttccga
     2881 cacccgatgc gttagcagaa gcttcaatcg atgaaatcat tcttaaaata aaaacgattg
     2941 gtttgtatcg aaataaagca aaaaacatca aagcgtgtgc acagcagctg attgaacgtt
     3001 tcgatgggca agtgccaacg tcaagagaag aattgatgtc tcttcctggt gtaggcagaa
     3061 agacagcaaa tgtcgtattg ggggatgcat tcgggatacc agcaatcgca gtagataccc
     3121 acgtggaacg tgtctcaaaa cgcctgagga tctgcaaact agatgctacg gtcatggaag
     3181 tagaagaaac actgatgcgg aaagtaccac aagaattatg ggtaaagaca catcatacac
     3241 tgattttttt tggtagatat cattgcacgg caagaaatcc caagtgcgag gtatgtcctt
     3301 tgctatcaat atgtcaagat gggaaaaatc ggatgcgtct aaaagaaaag gcgctaaaaa
     3361 agaaaccacg cctgtagacg tggtttcttt aattgcaaat aaatgtatga attatcttgt
     3421 tattatggag aaaagctgtt tcgtttatct tttttgcatg aaaaagtaaa tgtacatact
     3481 cagtagctag gatggtaact tattacaatt tattgcgata aaaataaaag ttgttatttt
     3541 tattgggaaa atacccgatg tagaaaataa tgccttccaa tatacctata aaataagtcc
     3601 agtattccaa aggattatat aaataagtga cgtatctatc taaaggtgta ataaaaatga
     3661 taagtgataa taaaaaaata ccatttataa ctaaacataa actaatggat ttgggcggtt
     3721 tcaggctcat cagaaaaata tagattctgg tgaacaacaa ccataaaaaa gtgagaatca
     3781 ttgcatgaga gcttctttcc ataaattttc ctttaagagt agtgcttaaa agtacagaaa
     3841 aaataataaa tgcaaggata ggagcaatta aagtaaattt atttaataat aaacaaaatt
     3901 tttcagcttt tttattcttg gaataacgag gtattgtttt cgataaaaaa agatggtgca
     3961 gacaaattat gataattaag catactatca gataactcaa aatgaagcct tctttcaaaa
     4021 aattattcaa aaccatatat tgtatttttt atttgataat aacaatggga ttattaagaa
     4081 gtggcactaa ataaaagact agtgtgtatt tagccgattt aattataaac aagtaaatgg
     4141 ataaagtata tgtaatgata aaagaaaaat ggattttcta atttttaagc taaatgttag
     4201 atcacacatg tatatgctgg atagtcttat aaaaaatcat gtaatacagc ttggtacatg
     4261 atttttattt gtagctgttt tttacataga cacaaaaaag aaaccacgct tgtagacgtg
     4321 gtttcttttt tactatctgt ttccagaagc tgaggtgctg ctggatggtg tatggtcatt
     4381 tgcagcatcc gctccgctag ttgctggctc actggaagaa gcaggaggag cagatgaaga
     4441 cggtgtcgag ctttcttcgg atgaagaaga aggaaccgtt gttgaagacg ctggctcgct
     4501 tgtttctgct gtcgtgcttt cttttgagga ctcagcagtt gattcgcttt gactagtaga
     4561 gctagagctt tgagtcgttg tctctgttgt tgagcttcca ggagtctgga catagctgga
     4621 agatggaata gttgttgatg gtgtaattgc attcgatcta gctgtatatt gatctttgta
     4681 gtacagttca ccgcccacac gaattaatcc gcttggcatc tcccagtctg tatttgtcac
     4741 gttagctgaa acatactgca taagctcgcg ataaacatca gaggctacgt gtgacgattc
     4801 tgaagtgaca ggcgtcattt ttttattgta acctgtccac acggaaatcg aataatttgg
     4861 cgtatagccc gcaaatagga tatctggata caccccagaa gaaataccaa gttttgcata
     4921 ctcgtcatct gtgtaattgg atgttccggt cttaccggct tgatataacc cagcgatttg
     4981 cgcattcgta ccagttcctt cagtgatcgt atcttttaaa atgtctgtga tcatataagc
     5041 tgtttctgga gacatggctg tttttccatc tggctcataa gtttcttctg ttccgtcttg
     5101 gaagacgatt ttattaacat attgaggttt gtaataagtc cctccattgg cgaaagccgc
     5161 ataggctgct gccattttta aggaagaagc tccgtatttt gtcccatctt gttcttccgt
     5221 attactagag atcgcattcg attgatggat cgtactgtat tcgatcccaa gattttttaa
     5281 gaaagaagcc actttatctg aaccgacttc attgaataat ttgactgctg gaacattacg
     5341 ggataagtaa agtgcttggc gtaaagtaat ggtgcccata tattgattat cccagtttcc
     5401 tacaggagtc gaagtccctt catagttata cggtgcgtca gtaatagttt ttccagtaga
     5461 atatttcaaa tattcaaaag ctggtccgta atctgtgaca ggtttcatcg tagaaccaaa
     5521 atcacgggaa gtattcactg ctaagttgtt gcctaaagtt acgtcttctg cgatgtgacg
     5581 tccgccaatc tgggctttta ctttcccggt attggtgtcg ataagggtgg aggcaacttg
     5641 catctcgtcg tctgggtaag agacatactg atccgtgttg acgatatcat atagtttctt
     5701 ttgggcgtcc agatccaaat tcgtataaat ctctaaaccg tctgtgtaga cattcttatc
     5761 tgttttttct tgtacttcat tgatgacttc tttgacataa ttatcgacga tcttagtatt
     5821 gtcatcggat tgagttagtt cttgcagacc atccgttacc ggtacattaa cagcttgatc
     5881 atattctgtt tgagagattt tttcgttttg aagcatcgta tacaaaacag tatctcgtct
     5941 tttcttcgcc tgatctggat aaacataagg atcataggcg gaaggggctt gaggcatccc
     6001 agcaagcaat gctgtttgcg gtaaagaaag ttctgataat ttcttaccaa agtacatctc
     6061 agaagctgtc tccatcccgt acaagccgtt tgacatatac actttattta cgtagtaggt
     6121 caagatctct tgtttcgatt ttttttgttc caatcttaca gccatccacg cttcttgggc
     6181 cttgcgtttc agagtctgat cctcggcact ggtggagaag aaggaaagtt tgatcaattg
     6241 ctgtgtcaaa gtacttccgc cttgcagtcc gccagaggta aagttagaga gggcagaacc
     6301 gatgatccga atagggtcaa ccccgatgtg tttataaaaa cggcgatctt ctaccgacac
     6361 gatcgcatct tctaatgttt tcggtaattc attcgcagaa attttttcac gcttttctgc
     6421 gcctaaatct tcgaatagtt cgccatcttg tgtatatagt ttggaagata cggtagcgtc
     6481 taatttttta tccgtcaatt cgggcgcatc ttttgcgtaa taccagaaaa gtcctacacc
     6541 tgctaaaaag aggatacaga aaaatgagag tattcctaaa aggatcttga taaataatcc
     6601 ttttttatgt gttccagagg actttccaga acctttgcca gaattcttct tcacactctt
     6661 tttaggagta ggctgtttct gtcgtctaga gcttctagtt tgttcatttg ccattcttgc
     6721 tttctccttc aatagataat gttgataaat agaagtcaac cgcgtccaaa taaggaatcc
     6781 gcggagaaat accagttttg atctctattc ctagttcttc gatcaaagat aaaggtagtg
     6841 atttgcgtcc tttttccttt tgggcgtccc agtaagcaat caaatgaaca ctattcaaat
     6901 aaaaacagcg cttcaaagac gaaaaccata acaagacaaa gcagacccca ttttgttcga
     6961 ggcatgcttt catatgttcg atttgatggg catggaagtt tttaaaggga aaagatgttt
     7021 tgttcttggt ttcttttgct tcaaagtcca agtaaaagcc tcgatagacg ccattatagt
     7081 ctgtagttga ggcttgggta aagtaggctt ccttgatcac agcagcactt ctcttaggat
     7141 agtctacttt cacgatttgg ataggggtag gctttttatg gataaccgcc aacccgcggg
     7201 aaagataata tttattactt tcattgattg cttcttcaaa gcgcatcccc cgattgccga
     7261 attcagtgat ctgatttctt ttttcttgaa ttttttcgac gggagaggca ttcttataat
     7321 aaggttggcc atttggatag cgcaatacca tctttaatca cactcctagg ccacattata
     7381 gcaaaaaagc ggatagaaag aaaaggaatc tgagatggat aagtcaaaag taatctatgt
     7441 gtctgggtat cgaagtttcg aactcggtgt ttttaaagaa aatgatccta aaatccaagt
     7501 tgttaaaaat gttttaaaaa aagaactcca tcagttagca gaagaagggc tggaatgggt
     7561 acttgtcagt gggaatttgg gcgtcgaact atgggctgtg caaatagtag cggaattgaa
     7621 agaagaatat ccggaactat ctcttggtat tttgtatcct ttttctgatt ttggtaataa
     7681 ctggaatgaa gggaaccaag aaaaaaaaca attagcagaa caattagcag attatgtcga
     7741 agctgttagc catcaaccct accaatcacc tagtcagcta aagaatcaca ctcgttttat
     7801 acttgagcat acagtgggct gtctgctgat ctatgatgaa gaattccctg gaaaaacgaa
     7861 gtattttttt gaagatgcac agaattacca agcagatcat ccctacgaaa ttcggctgat
     7921 cagtatggac gatcttcaaa attttagtga ataatcgata ttgtgtttga tttatcaact
     7981 tttttcctat acaatgaaaa aggtagaaat gttattacgt aaatgaaaac tagaggtgta
     8041 aatatggcga atttggttta tagtcctaaa gacattttac aacaagaatt caaaacaaaa
     8101 atgcgcggct atgatcccgt tgaagttgat gaattcttag acaatatcat caaagattat
     8161 gaaacttaca gcaaagaact ccttgcttta caagaagaaa acgatcgatt gagtgcaaaa
     8221 gtagctcaat tatctaaaac tcaaggagca gctcaaacac gcgtgcaaca aacagaggca
     8281 ccaaagagcg cagcagtgac caattttgat atcttaaaac gcttgtcaaa tcttgaacgt
     8341 gaagtatttg gtaaaaagct tgatcaacaa gcaagtgcag tcaaaccagc acaacctaat
     8401 ccaaataact acacaaatgc agacacaagc ttagatgata atgaaaaaac acgtcaattt
     8461 taatttttga ttaatgaatt tgcggttttc gggtaatcgc ggtctgactt gatcaggctg
     8521 aggaaagtcc atgctcgcac aggctgtgat gcctgtagtg ttcgtgctta gcgaaaccat
     8581 aagctaaggt actctttgga gtaacggcag gaaaacaagc taaggcttcg gctatgctta
     8641 agtatccttg aaagtgccac agtgacgaag cggctgggga aacccatccg gtggaacgcg
     8701 gtaaacccct cgagcgagca acccaaacaa tggtaggggc gctttttgtc tggaagaaga
     8761 acaggacaaa aaggcagtat aactgcagat agatggttac cgctttgttt tttctccctg
     8821 gaaaagcaaa gtacagaaca tggcttatag aaaaccgcaa acatcaggga attaggtcgt
     8881 gacaaaagta atgcgttata agaaacaaga aaaacatttg aaagctattt ttcaatactt
     8941 cagatgaatc gttcttatta caaaacaaac ttttgtatca ccggttattc ggaatttgag
     9001 taaaagtgtg gggtaggact gatgtcccac ctcctttttt tataaataag gagattgtgt
     9061 atggaaaaaa acaggaagtt caacctcgtc gcaactgcgg caagcgggct agaagcactg
     9121 gttggtaaag aattaagaga tcttggaatc gaatgccaag ttgagaacgg acgtgcacgt
     9181 tttgaaggaa caatggaaac gatcgctaca gctaatttat ggttacgtac agcagatcga
     9241 gtaaaaatcg tggttgggga attcgatgcg tatacgtttg atgaattgtt tgaaaacgta
     9301 aaagcattgc cttgggaaga ttttcttcca ctagatgcag cttttcctgt agctggaaaa
     9361 tcgatcaagt cgaaactata tagcacacct gattgccaag cgatcacaaa aaaagcaatc
     9421 gttgaacgtc tccgtaccta ttatcaccgt ccagcttctg taccactgac ggaaactggc
     9481 gcacattttc agttggaagt agctttgctg aaagaccatg tgatggtaac tctggatacg
     9541 acaggaccaa gtttattcaa acgtggttat cgcttagaaa aaggtggagc accattgaaa
     9601 gaaaacatgg cagcagcact tattatgttg acaaattggc gaaaagaccg tccattttat
     9661 gatcctgtat gtggttcagg tacgctttgt attgaagcag ccttaatagg ccataatatc
     9721 gcaccaggat tcaatcgtga gtttgcttgc gaatcttggg attggttcag tcaagaaatc
     9781 atggaaaatg ttcgatcagc agccgaagaa aaagcagatt atgatattga attagatatt
     9841 actggttcag atatcaatgg acggatgatt gaaattgcca aagccaatgc agaagaaatc
     9901 ggattaggct cttcgattac ctttaagcaa caagcagtca aagacttcaa aacggataaa
     9961 gaatacgggg tcatcgtggc taatccgcct tacggagaac gtctaggaga agaagaaact
    10021 gttcggaaat tatataaaga aatgggcgat gtattccgtc cattaaaaac atggagtaaa
    10081 tatatcttga ctagcgactt agcgtttgag gaattttacg gacaaaaagc aaccaaaaaa
    10141 agaaaattgt acaatggtgc attgcgtacg gatctattcc agtattgggg aactcgtccg
    10201 cctagaaaaa aagagaaaga cgaataatct tactaattga ttcattcaat tggatgtttg
    10261 gaggaatagg gaatgaaaga aaaagagttt ttacaagaag taaaagaaat caatcttcta
    10321 caacaagctt taggaatcct cgattgggat acacaaacag gtatgcctga aaaagctagt
    10381 gcataccgaa gtgaagtaga cagctatctt tacagcattt atttttcaaa aaaaatcggt
    10441 ccaaaaatca aagaagccat tcgctatttt tctgaacatc cggaagaatt gtcggaagtt
    10501 ggaactgccg tttttgccaa agtaaaagaa gagtatgatt tggaatatcg cgtaccggaa
    10561 gatcttatga gaaaatatac agctgccgtt tcttcagcac acggacaatg gcaaaaagct
    10621 agagaaacac aacaattttc tgattttcaa cacgcattga atcaaaatat tgaattaaca
    10681 aaacagttga taccttactg gagaaaagat gaaaagacga attatgatgt tttgctgaat
    10741 caatacgaac ccgggatgac tgtcgaaatc cttgataagg tatttgatca gcttaaagaa
    10801 ggaattcttt cgatccgccg tacgctccaa gaaaaaggga ctgaacctga aacagacttt
    10861 ttaaatcgga gaatgacgaa aaaacaacag aagagatttg tagtgaaagt aatcgaacaa
    10921 cttggttatg attttagtcg tggtcgttta gatgacactg tccacccatt tatgactgga
    10981 attaatccga atgatgcacg aatcacgaca cgatggaacg aaacagattt caaaatggct
    11041 gtttttggag tgatccacga ggctggtcat ggtatgtatg aacaagacat cgatgataaa
    11101 tatgcgtata caccggttta tgaaggtaca tcaatgggta tccatgaatc acaatcgttg
    11161 tttaacgaga tcattattgg aagtagtcgc agcttctgga aaaagcaata tcctttcttt
    11221 caagaatgtg cagaaggaac attcgatgat attccttttg acaaatttta tcgttcattg
    11281 aaccatacaa aatcaagttt ggttcgtatc gaggcagaca gtttgactta ccctctccat
    11341 atcatcattc gttatgaaat cgaaaaaatg attttcaatg aaggggtaga tgttgctgaa
    11401 ctacctgaaa tatggaatca aaaatatgaa gagtatctgg gaatacgacc aacaaatgat
    11461 gtggaaggca tcctacaaga cgttcattgg tcaggtgcaa gctttggtta ttttccctct
    11521 tatgcattag ggtacatgta tgcggcacaa ttacttcatt ctttgcagca agaaatagat
    11581 gtggaaaatg ttctagcgtc agacgattat tctccaatca aaaactggat gtcagagcat
    11641 atccatcaat atggtgcatc tagaaaacca aatcaattaa tcatggatgc aacacatgaa
    11701 ccgcttaatc cgcaatacct gatcgactat atgaaagacc tgtattttaa tgtatatcag
    11761 gtaaaataaa atacaattta caaagatagc tgaaattcat ctaatctata gatgttttca
    11821 gctatttact taagaaagaa gtggaacgaa tggataaatt acaagtgatc gctgattata
    11881 gtatggacca attagcgcat gatcaaacag gacatgggag cgatcatacc aaaagagttg
    11941 tcaagttagc tgaaaaaatt ttggagacgg aaccgcaggc agaccgcttt gtgacgcttg
    12001 cagcagctta cctacatgat acgattgatg ataaagtcgt taaaaatgag aacgaggcaa
    12061 agcaacagct tcgtgtattc cttcgctctt tgccaatagt agaggaacag atctcgatga
    12121 ttttttccat tatcgaaaat atgtcctttt ctaaaaatct ctctgaagcg gccgaactat
    12181 ctctggaagg taagatcgtt caagacgctg atcgtatcga agcattagga gcaatcggca
    12241 ttttgcgtac tgcttatttc ggcggtggac atgggcaccc gatttttgat cctgaactgt
    12301 atccgcaaac attcaaggac aaagaaaatt accgaaaagg cacgacagtg atcaatcatt
    12361 tttatgaaaa actgttcttg ctgtctgata aaatgaatac tgattacgga tatgaagaag
    12421 ccaaacgaag agaaaccttc atgcgtgaat tcttagaaga attttttctg gaatggtcta
    12481 ttgacgatga aaattttact ccagacaatt ggatcaaaaa taacaaaaaa tgatggaggt
    12541 tgtgacagaa gtggtcagct ccaagatatt tcggatcatt ttccgtaaaa gttacttctg
    12601 gaacactgtt taccaagagg tcgtgagcct gccgttcagc tccgagtcac aaggaacaat
    12661 ttcaaaaaat agcttctcgt gtttgatgaa tattgtaact tgtgattcgg aattggcagg
    12721 agaacaccgt ttatt
//
LOCUS       DBBGSP010000079        12732 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000079 DBBGSP010000000
VERSION     DBBGSP010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.079"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="ACIZE9_002671"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="ACIZE9_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGC6094482.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="ACIZE9_002672"
     CDS             complement(322..891)
                     /locus_tag="ACIZE9_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGC6094483.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="ACIZE9_002673"
     CDS             1077..1979
                     /locus_tag="ACIZE9_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HGC6094484.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="ACIZE9_002674"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="ACIZE9_002674"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGC6094485.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="ACIZE9_002675"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="ACIZE9_002675"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGC6094486.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="ACIZE9_002676"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="ACIZE9_002676"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGC6094487.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="ACIZE9_002677"
     CDS             8547..8732
                     /locus_tag="ACIZE9_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HGC6094488.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="ACIZE9_002678"
     CDS             complement(8794..9990)
                     /locus_tag="ACIZE9_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGC6094489.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="ACIZE9_002679"
     CDS             complement(10160..11596)
                     /locus_tag="ACIZE9_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGC6094490.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="ACIZE9_002680"
     CDS             11889..12698
                     /locus_tag="ACIZE9_002680"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6094491.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3801 a         2672 c         2250 g         4009 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt ga
//
LOCUS       DBBGSP010000080        12670 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000080 DBBGSP010000000
VERSION     DBBGSP010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.080"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            6..305
                     /locus_tag="ACIZE9_002681"
     CDS             6..305
                     /locus_tag="ACIZE9_002681"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC6094492.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACIZE9_002682"
     CDS             378..1739
                     /locus_tag="ACIZE9_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HGC6094493.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACIZE9_002683"
     CDS             1761..2021
                     /locus_tag="ACIZE9_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094494.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACIZE9_002684"
     CDS             2035..2787
                     /locus_tag="ACIZE9_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HGC6094495.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACIZE9_002685"
     CDS             complement(2881..3486)
                     /locus_tag="ACIZE9_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6094496.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="ACIZE9_002686"
     CDS             complement(3539..4513)
                     /locus_tag="ACIZE9_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HGC6094497.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="ACIZE9_002687"
     CDS             complement(4891..5610)
                     /locus_tag="ACIZE9_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC6094498.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACIZE9_002688"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACIZE9_002688"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGC6094499.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="ACIZE9_002689"
     CDS             7161..8558
                     /locus_tag="ACIZE9_002689"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC6094500.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="ACIZE9_002690"
     CDS             8639..9079
                     /locus_tag="ACIZE9_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGC6094501.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="ACIZE9_002691"
     CDS             9227..9553
                     /locus_tag="ACIZE9_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC6094502.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="ACIZE9_002692"
     CDS             9554..10303
                     /locus_tag="ACIZE9_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HGC6094503.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="ACIZE9_002693"
     CDS             complement(10383..10838)
                     /locus_tag="ACIZE9_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGC6094504.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="ACIZE9_002694"
     CDS             complement(11265..11540)
                     /locus_tag="ACIZE9_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094505.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="ACIZE9_002695"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="ACIZE9_002695"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGC6094506.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
BASE COUNT         4054 a         2175 c         2588 g         3853 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag
//
LOCUS       DBBGSP010000081        12432 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000081 DBBGSP010000000
VERSION     DBBGSP010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.081"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..190)
                     /locus_tag="ACIZE9_002696"
     CDS             complement(<1..190)
                     /locus_tag="ACIZE9_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094507.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(200..1015)
                     /locus_tag="ACIZE9_002697"
     CDS             complement(200..1015)
                     /locus_tag="ACIZE9_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6094508.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1277..1720)
                     /locus_tag="ACIZE9_002698"
     CDS             complement(1277..1720)
                     /locus_tag="ACIZE9_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HGC6094509.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1854..2192)
                     /locus_tag="ACIZE9_002699"
     CDS             complement(1854..2192)
                     /locus_tag="ACIZE9_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC6094510.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2180..2557)
                     /locus_tag="ACIZE9_002700"
     CDS             complement(2180..2557)
                     /locus_tag="ACIZE9_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC6094511.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2781..3974
                     /locus_tag="ACIZE9_002701"
     CDS             2781..3974
                     /locus_tag="ACIZE9_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6094512.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4140..4562)
                     /locus_tag="ACIZE9_002702"
     CDS             complement(4140..4562)
                     /locus_tag="ACIZE9_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094513.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4957..5151
                     /locus_tag="ACIZE9_002703"
     CDS             4957..5151
                     /locus_tag="ACIZE9_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094514.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5148..5594
                     /locus_tag="ACIZE9_002704"
     CDS             5148..5594
                     /locus_tag="ACIZE9_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094515.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLS"
     gene            complement(5804..6976)
                     /locus_tag="ACIZE9_002705"
     CDS             complement(5804..6976)
                     /locus_tag="ACIZE9_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC6094516.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7182..7997)
                     /locus_tag="ACIZE9_002706"
     CDS             complement(7182..7997)
                     /locus_tag="ACIZE9_002706"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HGC6094517.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8147..8593)
                     /locus_tag="ACIZE9_002707"
     CDS             complement(8147..8593)
                     /locus_tag="ACIZE9_002707"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HGC6094518.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8590..9105)
                     /locus_tag="ACIZE9_002708"
     CDS             complement(8590..9105)
                     /locus_tag="ACIZE9_002708"
                     /inference="COORDINATES: protein motif:HMM:NF037639.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HGC6094519.1"
                     /translation="MDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFT
                     SSKDGTFSVHGLSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEP
                     KANPTNNGKTPVQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKK
                     QQKGNNRREIK"
     gene            complement(9178..10092)
                     /locus_tag="ACIZE9_002709"
                     /pseudo
     CDS             complement(9178..10092)
                     /locus_tag="ACIZE9_002709"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
     gene            complement(10089..12416)
                     /locus_tag="ACIZE9_002710"
     CDS             complement(10089..12416)
                     /locus_tag="ACIZE9_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBG domain-containing protein"
                     /protein_id="HGC6094520.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         3513 a         2430 c         2272 g         4217 t
ORIGIN      
        1 tgcaacctgg accaataaaa agtaaagaaa aaataaagga aaagacattc cttccatcta
       61 tcgacaaaag gaacgcagct gctatataca agatattgac acaccaaaaa caaaggctac
      121 ttgccaatga ttgatacaac caataaaaga attccatata aacatttttg tcaaaacgct
      181 gctctttcat aatcacctcc tattccttca ttcctgatga agcgatccct tctacaaaat
      241 atttttgcat cgctaaaaat ataaaagcaa caggaagaac agaaacaact gaggcagcca
      301 tgattaatgc gtactctgca tcaaatagcc caataaacat tttcaaccct aactggattg
      361 ttttattttc cgtagaagac aaataaatga atggccccat ataatcgttc catgtattaa
      421 cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc
      481 gatagattcc ccactctgat aagccatcga tccgcgcact ctcacataaa gaatctggga
      541 tactactgta gtattgcttc aacaagaaca caccaaaagc attgaacgct tgtaatagca
      601 ccaacgacca caacgtatat gttaaaccca cttttctcat cataatgaac tgcgggatca
      661 tataagactg ccaagggaca gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc
      721 ctttaaaatt tagtttagaa aacccgtaag cagcaaaact agaagtaaac aactgaatca
      781 acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag
      841 accaaataac cagataattc tctaaatgcc aagttttagg gatccattga atcggaatcg
      901 tgaacacttc attatttgct ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg
      961 tcaataaagc taatacaatc agcagaatca tacccaacca ttgaataaag ggcatgtttt
     1021 ttgaacgaat ttttgctttt tttctttcat ttcgaacacc tccaaagtta taatcttcat
     1081 ttctttgtaa tgattacaat ccagaacaac ggttattata gctgattcat ttccgttctt
     1141 cttatgtttg taagcgctta tttaacaagt tatgtaaatc tctttatttt ttttgattta
     1201 aaaatgaaaa aatacaaaag caagactgtc atacgtctcg cttttgtatt gaaatttctt
     1261 cgattagaga tacttattac tgttcaaaag cttctttgaa acggtgaatc aattcattga
     1321 ctacaggtga taaaatccga ttctttttcc agactagcat gcagttcgtt tcaatcattg
     1381 ggtcaagcgg aacgaatgtc actcgctttg aaagatgact tacagcacct tctatgacta
     1441 aagcagcacc tacctgattc tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc
     1501 ctgtgatcag caactgctcc ttttttatgc ctaaccagtc agcaaacatt cgctgtattt
     1561 ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt
     1621 tttttgctaa aacagaattt tctaaaatga gcaatcccca tttttccttt cttggtaaca
     1681 aaatcgtttc gtatttctct gtatctactg gatctagcaa aatcgctaaa tctaacaggc
     1741 ttttttctag tcactccgtg atatcatcac ttgttccgct gtggatatga aattgaacgc
     1801 tgggataatc acggatcaac ttttctagta atagtgccaa tgtattcgaa ttatcagctt
     1861 ccacacagcc gatcgtaaat cggccgctga ataattgttt ttttctgttc tcgaattctt
     1921 gagtggtttg attcgttaaa tctaaaattt cttctgctcg gcttttttag aaaataacct
     1981 gcttctgtca agatcatttt gcggttttcg cgtacaaaca gttctgttcc tagttcctct
     2041 tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct
     2101 tgagagattg ttccttcttc tgcaattgtc caaaaatatt ttagtaagcg taactccata
     2161 gcgatgctcc ttgatttttt tacttgatac attccatttt atttctagat aacacacgat
     2221 catatttctt gatttttcct tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt
     2281 tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc
     2341 cttcgctaga taggcgaata tattcaatca aagactcgat cgataatccg gcatttcgca
     2401 tacagatcgt aaagtcgacc cattttaggt cttcttctgt ataatcacgg attccgcctt
     2461 ttgtccgatt aactggtgga atcaacccga ttcgttcata atagcgcaat gtatcggccg
     2521 aaatgccctt ttcttcactg acttgtttga tattcatctg atcactcttt ctcttaattt
     2581 cttgccactt tacttatgta ttttatttat tctacaactt taagtgtact ccaagtcaat
     2641 actcatttct attaaaacta agctggatta tctatatcgg ttgtttgtgt attatttcaa
     2701 ataaaaaagt cttgtttttt tattcttttt tggatatact tttaacaatt tagggaaatt
     2761 ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa ggtattatta tcgacatcgg
     2821 cgggaattgc tttagagaat atggatatta tgtttttagc tttttcatta tcttcaatga
     2881 ttacttcttt tcatattagt ggtacgcaag cgggtttcat ttcaacgatc actaatttgg
     2941 ggatgctcat tggaggtatt ttttttggca tcatagctga taaatatgga cgtgtgaaag
     3001 tattttctca aacggtcctt ctgttttcga ttgcttcttt attgatgtat tttgcttcaa
     3061 acatctactt ggtttatctc tttcgcttta tcgcaggtgt aggagcggga ggagaatacg
     3121 gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt
     3181 cggttgctgg tattggtgcg caggtcggtg cggctttggc tgcgatttta gctgctgtga
     3241 tcattccaac gtttggttgg aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg
     3301 tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt caaatctgta caatctgccg
     3361 aaaagaaaac caaacttagc agactgtttg aatcaaaaca tcttgcttgg caaacatgtg
     3421 gccttagtat catggtaact gtccaaattg ccggctattt tgggttaatg aattggctgc
     3481 cttcaattat gcaaaatcga ttagggcttt cggtttctgg gtcttcattg tggatggtca
     3541 gtactatttt aggcatgtct ttggggatga tgacttttgg cataatcatg gataaattgg
     3601 ggcctaaact agccttttct ttgtttttaa tttgttcatc cttatctgtc tatctacttg
     3661 tgttagccca tagccagtgg agtttggtag cagccgctgt gatagtcggc tactttatca
     3721 atggcatgta tggtggatat ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg
     3781 cgacggcgaa taatttcatt atgaaccttg gacgagctgt tggtggtttt tcttctatcg
     3841 tcatcggttt cttgatggat cattatagtt taactgccgt aatcttgttt ttgagcggta
     3901 tttacctagt cagtctgctg gtcttgacaa ctcttactgg tgttacagca ttaagggaaa
     3961 gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc
     4021 atctgcggta ataagaccag ccaaatcaaa aacatgagac actgtttccg tttggctggt
     4081 cgtattactt gatgcagggc agctttttca actgctaatt tccttctatc tggcggcgac
     4141 tattctttga cgtccgtcat ttcaaagtac tttactaata acttagcata acgaaaaact
     4201 gtggatacac tcgtatattg agcgtctgca taatcttcca aatttttctc aggatgttga
     4261 tacatgaatt caatcaaatg ataattatat gattttctgt agaaatgaag ataaataatg
     4321 tagattggga agttctcctg cttttccata gaaaagcgcc gattattctc attcttcaaa
     4381 atgaccttat caggatattt ttggaacaat tcttctaaat ctgttagata attcaagata
     4441 gacttacttg ataccttcaa ttcgttttgt agttcttcta ttgaacacca acgttctgtt
     4501 tcaagcagta aatgaatcat tttaattttc ttttgagaaa cttttgttaa aaaagtctgc
     4561 atattttctc ctcctgtatc tactttacta tactacatac aagaaaaaaa acggatacaa
     4621 atatcatatt gtcacaccgt caatagtgca taaacctgtt attatttctc tttttttcct
     4681 aagtattcta ttgatatgaa tcatttaatc gtttattata taaatgtcaa taatctaata
     4741 ataaaataac gtacatattt tattattgca tacttaataa cagaactata gcaaaaaatc
     4801 ccgtgtatca acacgggatt agattaagtt tcctcaatca ctattcataa cacaattatt
     4861 ataacaagta agtaaacaat tgaaaaggac atttattgaa aacggttgtt ttttacttaa
     4921 ggaggaaatt tagcgaaaaa attagttgca ttgtttttgg tcgcaggaag tttgttgagt
     4981 gggtgtggtg ctactacgtc tactactcaa agcacaagtt cagatcaggc ttccagcagc
     5041 agtaccacga tctccgaaag tacggcagat tcatcgaaag aacaagaaca aattgaaaag
     5101 aaaaaagaag agaaacaaaa agcggaaaaa gctgcactag aaaaaaagtg acagaagcgg
     5161 aatctgcttt gtcacaagct gaagcaaatc ctacaaaaga aaactatgca actgcttcag
     5221 cagctatcca agcgctacct gaaaacaaac aagagttgac aagccgtctt gctgcaattg
     5281 attccacaat caaagcaaaa gaagcagaag aagaacggaa aaagcaagaa gaaattgcac
     5341 gacaacaagc agaacaagcg caacaagaag caatcgcaca gcaacaagca gaacaggcga
     5401 ggcaagaagc aatcgcacag caacaagcag aacaggcgcg acagcaatca gcagctgaac
     5461 aggcctctca gcaggcacaa gccgcagctc ctgagcaaaa taatgaacaa actgtctatg
     5521 tcacaccgac cggttcaaaa taccatacac ataaatgtgg aaatggtacg tatacccctg
     5581 ccactttaag ctaagctcaa gctcgtggtt taaccccttg ctccaaatgt tatggaaact
     5641 aattcaaaag ttatactata ataataaaat tcttctgaaa cataaaaaaa tagaagatgg
     5701 cgttccagat agtaaaccaa aaataacagt ttacacgtcc atttcgtcag cttctctctt
     5761 ttttcattta gtctgttccc tctgcttttt tggacatctt cattcattct ttctcaatca
     5821 aatagtacac ctctttttct tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa
     5881 actgtttcga atgtttatgt tttacatgga ttttaagcag gagctcctca tgttgcaagc
     5941 gatagttcct gccttttaaa tcagaaaatc tcactagtcc gtattcatca gaagctttca
     6001 caaatggaac tttttctcta gtaatatagt gtttgccgtt gagcgttttt acagaaaaga
     6061 ccattccttc gattggtcgt ccgtttgtgt tctttacata aaaagataaa ggatagtttc
     6121 gcttagcgat ggccaaagaa tctaaataag cgatgagtag ccaaactaag ccgattgatc
     6181 caagtagtat accgataaac caaataaaaa atttccattt tttccattga tcaattcctt
     6241 ggatcgcttt ttttgcctct tttgcttgat aaggaatacg atgccccgtc acaagcagtc
     6301 gatgtgtatt gaccatataa ggagtacagg taagcaaagt cacgagatct ctgccttttt
     6361 ggatacccaa agaatctact tcatcaggta agaccacttg gattttttct acttgatacg
     6421 ccaatgtctt tccattgatc tggatgaaaa actggtctcc ttttttcaac ttaggcaaat
     6481 ctgtaaataa ttttgcttct gggagtccac gatgcccaga aagaacggca tgggtgtttt
     6541 tcccgccagt cggataagaa ctttcttcca ataatgacgt tcctttttgc aaaaatattt
     6601 ccgttgtctg atcgaatata ggtaagctga cattgatttt tgggatttcg atgactccaa
     6661 gcatatgttc cataaaaaag gcattactag gtaaatcttt taatgctttt gcatcaactg
     6721 cttggttgaa actgcctatc cctggtgata cgttttgctc tgccaactgt tggtttttct
     6781 ttgtcatttt ttcctgctgt ttttttattt cctctgaatt cttattcgat gcttgctttt
     6841 gataatggat gatcatttgc tgggcaagaa aatcattcag tgaatcttct acaaaaggat
     6901 aagaaaagat cccgatccca acgactaaaa tgattgccat gaagatgtcc agtattctta
     6961 ttctgctttt attcatcatg tccacctatt ttctaatatg tatatgaaga ggttgtgaaa
     7021 tcagcgcctt gacctgagta ttagcgaagc aaacggcaaa atagttcctc ctattttgcc
     7081 gtttgttgag cgaataccaa gagaccgacc acttgtcaca acctttctcc ccatttgaat
     7141 cactatcgtt tatttatcgt atgatttttg tttccaatag tttaagcttc tgtttcttga
     7201 tggcgttttt tgaaatagat cactgctcct ccaactaaag cagtacctac caagatgaat
     7261 acgatgatcc ccataccacc agttgaaggc aagattcctt taggttggtt atcgatcgtt
     7321 gtttcatcag aagttgttgg atcatcatct actgtaaatt cagtgtacgc agcttcattc
     7381 ttaggtaatg cgtagccttc tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc
     7441 agcccttcga ttgaaaattt cccttctgaa tcagaaatca atttcacttc ttcccagtca
     7501 gaacctgtga cttcatctga ccaagcatat gggtattctc ctgaggcaag gtttgctatt
     7561 tttttcatta atttaacagt tggatctttt gctcttagaa tagaaaattc tgcatcggct
     7621 aatttttctt gcgtgttcac atcttgtttg atgaagtgga aatcaccgta gttttggaca
     7681 ttttctacag taatcgtgtt atccgtagtt gtattttccc gattgactac accgtttgga
     7741 ttcccaagat tggcttcatc tgcgccatgg atgataccgg ttgtttgttg caattttccg
     7801 ttttttacta taaaagtagt ttctttttgt ggattggtta attgataacc atctggtgct
     7861 tttgtttcaa ctaaagtata attgccgtct attaatccat tgacactgat ggatccttca
     7921 gtatcagttg tgaatgtcaa cgctgactca gcaggatcat agagagcgac accagtgttt
     7981 tcatcaaaac cggtcacgaa ttgattctct gaatttttga tctggaattg cgcccctgct
     8041 aacttatcta cccctgaaaa gttcccagct ttctggattt tgatattgct ttctttgatg
     8101 acatttttag catataggtg aatcgtgtct aaaggtttgt cagggtctag ggtaagctta
     8161 acacgatatt tggcgacgtt tcgacaccgg gctttggtgt ttctacaaag acgtatacag
     8221 catctttccc atcagattta cctggaagag tcaggttagc taatccttca ccagaagtcg
     8281 ttacacttgc gaagggtgta gcgtctgctg gaactgctgt gtctttactt ggatagtacg
     8341 tagcagtgat gtcatatacg ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg
     8401 tcaattccgt tccgttgttt atttgatttt ctggtgctga agtgaatttc aatttatgca
     8461 aattaaccgt aacattttct ggtgtaggtg atacggctgc agaaacctct gcagttccta
     8521 ggccgagaac gaaaggaagc agcatgatag cagttcctaa aaacgtccat atttttgttt
     8581 tgatgttttt cattttattt ccctcctatt gtttcctttt tgttgttttt tataaaacca
     8641 agctgtccct gttgaaagga ctagcaataa ccctaaaatt gagaaacctc caagcatctc
     8701 ttcgcttgtt tttggaaagc ttcctccatt tttttcattt gatggaccat ttgtctgcat
     8761 ctgaactggc gtttttccat tattcgtcgg atttgctttt ggttcgttga tgatttccaa
     8821 tggtatagga tgaagcggat cataactgcc tttttcaact tcaaagagaa tggttgattg
     8881 actcaatata tatcctttag gcggtttaat ctccactagt tcgtaacttc caaaagacaa
     8941 tccatggaca gaaaatgttc catctttact ggaagtaaaa atcgttgctc ttgaatcatc
     9001 tttggctacc caatgattta tcccgttttc ttgcgctaag tattggtcat tttttttgac
     9061 tagaaattga gcatctgcta gtttttgttt cgtttgccga tccactttga caaattgttt
     9121 gcctcctgtt tggatggcaa gatgtgtttc tactgtttga ttgtcagtcg tcaaacgtac
     9181 atcgttatca aatgtcgttt tttcactgtt ttctttcaat gtcatttggt aacggatcgt
     9241 taattttttt ccagcaaacg aactaagatc ttttccagaa tctgataaga caaaaccatg
     9301 ttttattttt tgtgtgtgaa atgtatgaat cttgtctcca ccaatcaaaa aatcgatcgt
     9361 ttctggttct agccataact gaggatcagc tgtatctttg atcgtatagg ttcctatctc
     9421 gttgatgttc tcaggaattg ttacggtgat gagataaggg actttatccc catctgcaaa
     9481 atctgtctgc ttattctcta ctgtttttgt taatgtgagt gcagcaggta ttttttgttc
     9541 gctctttgga tacaagtgga tggtcgtcaa tttatgatta gatgaatctg tcacaggaag
     9601 cacaacgaca aatggtgctg atttttcttt tacttaatct gaagtcttta tttccgtaaa
     9661 tcggtaaaca gcgtcacgac cttgctcatc tttgtccgat gcactaaaag aagcaatgcc
     9721 ctcttcctcg tctactgttt ttgtcacatt ttctgccagt attttttcac tatcactttt
     9781 ttgtgctagt tttctttgtg cgtcttccac actacttcct tctgaccgca gcttgtaaaa
     9841 ttcatccgag acatcatata tagcgaaagt aacgccgttc aaccctttta ctccttgaaa
     9901 gttatccggg atatttattc cgtcgttttg actgatactt ggcatcttat cgctttcgaa
     9961 cattcgatta tgcaaagtaa atgtaatagg tgattctcta gctgacacag tcggagaacc
    10021 tataaaaaag accagtagga taaaaaagag aacagcaaat atatccacac gtacattttt
    10081 tgtttttttc atcgctgttc acctgctttt ttcttacgat ggataaaata aaagaagcca
    10141 gaaaaaataa agatcagtcc taaaaagaca aagggcagta gacctatccc acctgtcgaa
    10201 ggaagcaaga gagtcggatt gatcgtcaac ttagcggtat ctgttgcgat aatcgtataa
    10261 ttattgttta cacttccttc gcctaaacta atcgttacta tttgtgatcc aatatctgtc
    10321 cggctgttaa ctgttagggt ataatccaat gattcgccta agacaacacc ggtaacgtgg
    10381 agatttccaa ccgaaatcga gtgactttgg gcatcataat taaaggcagc gtcatcgaca
    10441 gtaatcactg cgttagcttt atagatggta taagttcctg atgtgttggc tatatcagta
    10501 aatgacaact tgggatttgc tgctttgact ttgtctattc cgctattcgt tagtttaatt
    10561 gtatagctgc cagcattaac catatttttt gctgattgtg catctgctgt gtaatccata
    10621 ctgctaagtg ccacttgtac tggagtaagc gaactagtga caccctctgc tagcttgaca
    10681 tggattgacg ggacacctgc ttttccatca tatgtcttac tgccactgag ctctaccgca
    10741 ccgctgattt gcttaatcgt atagacatca gatgtctgca cgatagtaaa taaatagttt
    10801 gttctggcag ctagtttagc tagtccgctt tttgtcaatt gccaagacgt ataggttcca
    10861 atttcagtag gcgcagttac ttcaactccc ttttcattca tcgctttgaa atcagttgga
    10921 ttccatgtga tttgatcaat actgagatca ttgtttaaaa gggatgttga ttctgtttta
    10981 tcattaaagg catatttaac gatcggtaca acagaaagac catcatagta cttactgcca
    11041 tttgcattga ttgatactgt tgcatttgtc ttataatata ggatgacttc agaaatctgt
    11101 tttccatttg cgtcctttac gattacattt ccatttgtat ctaaactagc taaaacactc
    11161 attgctgatt ggttctttgt ttctatcgct gaaacagctg taaaggtata tccgttgata
    11221 gtaggcgtat tagtcgtcag gtcttgtgca gcacttccgt aagtaagatt cattatttta
    11281 gaaggagcaa tcatctgtcc aaaatagtct tgatacttaa tagtgattgg tgtttgtttg
    11341 cctgtatagg tcaccgtatc gacgttactt tctagggctg tgaaagaacc gtttgtttgt
    11401 gcaaaagaat agcccgttac tgctgttgga gtgataacca ctttgtcacc cacatggatt
    11461 ccagataatg tagtcccgta cgttccgatt tttgctgctc caccattgac tgtataagaa
    11521 aaagttcctg tccgattcgc attgacctga accgttgctg cttgataggt tggaaaattt
    11581 gaaacatttc ccttaccatc aacgatctgc ccatttttga tcgagtaccc cgtgaatgga
    11641 atatcatttg ctaactgtat accgattgaa aaagtactca tacctcctcc ggcaggaagc
    11701 cctccccatg ttgagggtgt aaaagaataa cttttatccg cattgggtgt aactgaatcg
    11761 atcgtatttc cagcggtagc cacccccata tagatacttt ttgggaatgt gatagtagta
    11821 ccatttactg tggagccaat aaacagatta tggatatctg gacggttatc aataaaagcg
    11881 attgctttgg ttacgccttg taacgcagtt ttatccgcac tcatcgatcc gttaaccgca
    11941 acaatgactc catctttggc atatatcact gtatatccat ctggtatggt atgtccgttg
    12001 aaattcgcag tggccgcaac agtactaaat gtctggcttc tacctgtttc tgaataagct
    12061 ttctcccctg ctgcttttgc tgctgtgatt tctttttctg tcggatcaat cagttgagtc
    12121 gaggatgtgg ttgaggttgt ctcgttgttg ctagactgat tggtgctttc tatggactgt
    12181 atttcagaat agggtggact atttgtctcc tctgtcgttt ggttagcaaa atttgacgtt
    12241 tctgtataaa cgtttacata aatacttgat aagctcccta agaaagtaaa aatcaagatg
    12301 atcgaaatca taatgggatg taagtatttt cttttagata cagctttgag tctagaaaca
    12361 aaatgttttt gacatatacg ttggatttta ttttgagttt tcttaatcat tttcatccct
    12421 cctctcaata aa
//
LOCUS       DBBGSP010000082        12359 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000082 DBBGSP010000000
VERSION     DBBGSP010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.082"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..465
                     /locus_tag="ACIZE9_002711"
     CDS             <1..465
                     /locus_tag="ACIZE9_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HGC6094521.1"
                     /translation="WKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQAAYAF
                     LKRLVKQFDEPKVVVTDKAPSIASAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVK
                     RRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPD"
     gene            complement(1081..2121)
                     /locus_tag="ACIZE9_002712"
     CDS             complement(1081..2121)
                     /locus_tag="ACIZE9_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HGC6094522.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(2470..2796)
                     /locus_tag="ACIZE9_002713"
     CDS             complement(2470..2796)
                     /locus_tag="ACIZE9_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094523.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2783..3571)
                     /locus_tag="ACIZE9_002714"
     CDS             complement(2783..3571)
                     /locus_tag="ACIZE9_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6094524.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3939..4229)
                     /locus_tag="ACIZE9_002715"
     CDS             complement(3939..4229)
                     /locus_tag="ACIZE9_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HGC6094525.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(4365..4544)
                     /locus_tag="ACIZE9_002716"
     CDS             complement(4365..4544)
                     /locus_tag="ACIZE9_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094526.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4541..4891)
                     /locus_tag="ACIZE9_002717"
     CDS             complement(4541..4891)
                     /locus_tag="ACIZE9_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094527.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4884..6209)
                     /locus_tag="ACIZE9_002718"
     CDS             complement(4884..6209)
                     /locus_tag="ACIZE9_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HGC6094528.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6659..7273
                     /locus_tag="ACIZE9_002719"
     CDS             6659..7273
                     /locus_tag="ACIZE9_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6094529.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(7438..7680)
                     /locus_tag="ACIZE9_002720"
                     /pseudo
     CDS             complement(7438..7680)
                     /locus_tag="ACIZE9_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7884..9203)
                     /locus_tag="ACIZE9_002721"
     CDS             complement(7884..9203)
                     /locus_tag="ACIZE9_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HGC6094530.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(9337..9945)
                     /locus_tag="ACIZE9_002722"
     CDS             complement(9337..9945)
                     /locus_tag="ACIZE9_002722"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094531.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSLNNSYF"
     gene            complement(10583..10840)
                     /locus_tag="ACIZE9_002723"
     CDS             complement(10583..10840)
                     /locus_tag="ACIZE9_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGC6094532.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(10833..11102)
                     /locus_tag="ACIZE9_002724"
     CDS             complement(10833..11102)
                     /locus_tag="ACIZE9_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGC6094533.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(11233..11412)
                     /locus_tag="ACIZE9_002725"
     CDS             complement(11233..11412)
                     /locus_tag="ACIZE9_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094534.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            11510..11746
                     /locus_tag="ACIZE9_002726"
     CDS             11510..11746
                     /locus_tag="ACIZE9_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094535.1"
                     /translation="MKQNTSIAKNTTKFKCTAAAWRISISPTNRTNNRGMILFIWISF
                     FLLGYRVLPAYFAPPKRRGRLERLVRNKNHSLSY"
     gene            complement(11793..>12359)
                     /locus_tag="ACIZE9_002727"
     CDS             complement(11793..>12359)
                     /locus_tag="ACIZE9_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094536.1"
                     /translation="EEQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETE
                     KYIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATID
                     DYYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTY
                     TYDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         3787 a         2256 c         1894 g         4422 t
ORIGIN      
        1 tggaaaatgg atgaaacgta catcaaaatt aaaggaaaat ggcattattt gtatcgagcc
       61 atcgatgcag atggtttaac cttggatatt tggttacgta aaaaacggga cacacaagca
      121 gcctatgctt ttcttaagcg gttagtgaag cagtttgatg aaccgaaggt tgtagtcaca
      181 gataaagcac catcaattgc tagtgccttt aagaaactaa aagaatacgg attttatcaa
      241 gggacagaac atcgtaccat taaatacctg aataatttga ttgaacaaga ccatcgtcca
      301 gtaaagagac gcaataaatt ctatcgaagt ttacgcactg cctcacccac gattaaaggc
      361 atggaagcca tccgaggatt atataagaaa acccgaaaag aaggcactct cttcgggttt
      421 tcggtctgta ctgaaatcaa ggtattattg ggaatcccag attaaatcat agataccgta
      481 agggatttta ttctttattt aaaactttgc aacagaaccg tccgttgcgg gtaataccgt
      541 aacactgaag ggcacgcatt aaggcgtcat cttaatgctt tcctgtagga cactgacgga
      601 gattaccagt ctcccgagcc ttacaggggc ctttcttttt tttgtatttt caattatcac
      661 aatttatcgt ccaaaagtgc agaacgaaaa tcaattcatc acaagcatat cagacaatta
      721 aatttaaaac aactaaaaat atacaaaaaa gtgtaattga atattagcag cactgcctga
      781 aaagaagtaa tatcaggctt ttcagcttgg ggaaataagt gaattacctc tcttcatgaa
      841 ttattataac tcaaaaaagc acatatgcaa acactagttc cctatttttt tgaatgaaaa
      901 ataactaaaa tatctaacga ttatgacttt aaaacctacg tttgtgattg ttttcataaa
      961 cttttaatct aaaaactccg gaataatagc tatttatttg taacatttgt aataaaatta
     1021 aaatcataaa aaagttctaa tttaaaattg atcattttta tagtgatcgc tttttatcaa
     1081 ctactctagc caattttccg tactaactgt tggtaattcg ttaaatgttt ctctttgttc
     1141 gtttgcaagc tttgccgcaa tagctttttc gacaaaccaa ttttttacat aaacgaaaat
     1201 tagattctgc aaattgttta ctttttcagt tttttgtttt tgataagctt tcagcaaagt
     1261 catatataat cctttgtcag catcaattcc ataagattcc agttcttcat aaacaacaac
     1321 tgtttgctct aattcttcag cttttttctt tgcattatga atagtttgga cggttttttg
     1381 agcgtcttcg taagtactag aaaatgtttt tatcaagttt aatacatttt ctggtacaaa
     1441 tgtatttata ctgtcctctt tcatgatgtc gacgaagtta tctagtaaaa cttgattttg
     1501 taactgatca gtttcagtgt ctattatgtg tctattagtg tctatagaat tagaatagaa
     1561 tagattgtct gcgattttcg caattacggt tgagtccttg atatgactgg attttgccgt
     1621 atttgcgatt ttcgcaatta cggtggtatc attgatttct cgcggttttg ccgtatttgc
     1681 gattttcgca attacggtgg tatcagtatt gtcttcctct tccatgattt taaagacgtc
     1741 ttgattcgtt acttctggct tgcctaagta caataaatta ggcatggatt caatcttacc
     1801 gtcacgttta tttactcttc ctctcttctg tttcagaaga cctgcttttt ctaattcctt
     1861 tttgatttta gatactttac cttcgcggca ttgtaacaat ttcattaatt cttcaactgt
     1921 gaatatgaaa aatatattat catcagaatc tacccagtta tttttgactg aataatcaaa
     1981 tcgatcttta agtagcatat aagcaatttt tgcatcattt gatagatcca tgtatttttc
     2041 gttagtaaaa aataccttag gcatttgata atatttttca cgataaattt cttttgattt
     2101 gtaataatta aaatcattca tagccaatcc tctttctgta ggatagcgtt ttgttcaaaa
     2161 ctatgttaca atgaattaaa caaatatatc tatccactat atatttttct actgctgata
     2221 agtcgccaaa ctttgttaaa gcagtagtct ttttttatct ttttttagtt taccttaaaa
     2281 aataaattaa agcaaaccgc tctatttcaa ggtttaagct catagtaact atatcacgat
     2341 attacaataa tattatatca cgatatcgta atattacaat atgaagataa gcgacttatc
     2401 agctttgata ctactgattt ttataaaaaa aatatcacga tattatgata tcgtgatatt
     2461 gaatgtaaat taaattttat tttgtttctt tgctagttta tatccttcaa tcaagtattc
     2521 ttcaggtatg gactttaata gcgcatcttc tataacgtct ggtttacttt tgtctgattc
     2581 agcaatagtc gtccaatatt tgagtgctga cattagaatt ggatttatac gaatgctatc
     2641 tgctgttctt acactacttc cttgatcttt tatgacttta cttatatttt tcttggttaa
     2701 ttcgatttct tctacttctt ttgatttaaa attcttttta tttttatttc ctagtaatct
     2761 acttactgca gcttgactgc gattatcttc tgccatcaaa atcaccaact tcttttaaat
     2821 attcttctgt aaatgcttta tagtcatctt cagctgttga gggtttatta aaattgatta
     2881 gatctgatcc agcagcttgc gcttcgtcaa cggttattgt cctacgaata taagttttga
     2941 aaatttttgc accaatgact ctagaaattt cggttgctgc agacgtcatt tctttagaaa
     3001 tgttataacg cttattatac ttagtaaata gaactcctcg tacttcaagc ttgtcgttcg
     3061 tatattcttt taccgtttca atagtttcac ttaactttat tagtcctttt aatgagaaat
     3121 acgcagcttc aactggaatg ataatttcat cagaaacagt aaatgcgttg actgtaagca
     3181 ttcctaaact tggtggacaa tcaattataa tataatcata gttgtccttg attggttgaa
     3241 gtactctttt aagcctgtgt tcacttccta cttgagtaaa ttccctctct gcagaagaaa
     3301 gggctatgtc ggctggcaaa acatcaattc ctttatagtc cagaatagca tctgtaatgt
     3361 cagcctcccc ttttaatact tcataaattg taggttggtt tgttccatct atatcgaaac
     3421 ctacattatc tgtagcattt ccctgaggat caatgtccac taaaagtaca tttttaccgt
     3481 aaacaaattt caaacatgct gctaaattaa cgctagtcgt agttttagaa actccacctt
     3541 tttgattggc tactgacaat attcttgcca ttaaaatatc ccccattcat cttatattat
     3601 aatataatta tatcataata ttgtgatatt gcaatatcgt atatgcatta tattgtaata
     3661 ttgtgtgatt attttgtttt aaagatatat atcggttcgg atataaagat tattcatatg
     3721 ttattcgaaa ttaaaataat cactttttat tactttaaaa ttttttatta atgataagaa
     3781 atatgttttg cgagcagcaa ctagaataat ttaaacatta ctaaactgtc tatattgtta
     3841 ctaataattc ccttcttata gtgcattttc ttagaaaaaa acaatattac gatatcatga
     3901 tattaagata tcgtaatatt atacaattgt gattgatatt atatatgttt ttttattttt
     3961 ttatcatgtt taatcttgaa ggaatcatat tctttttcta aagacaggag cttttcataa
     4021 acatcagaca tgtttaaact agaggccagg cttaaatcat aaacgaatga agcaggtaat
     4081 gattttattc tacgttgtcg ggttatccag cttgcaaccg ttccttgtgg gtaggcatat
     4141 aactcacaaa attgttctac agtgattcct aaattcttga taatgtaaac attgatcggg
     4201 tgcgagtaaa caaatgtatt gatagacatg gtgcgtaagc ctactttctt ttattattgc
     4261 gtttgcaata atagtttaac acacgcatta ttctagtatc tactcctatt tgtaaaaaca
     4321 aaaaaggatt catagagata actctataga atccgtaaaa taccttatat atataacggg
     4381 aagatataaa acctaaaatt atgataacct gctgcagctt ctacatagaa agagaagcgc
     4441 tcaacaccaa cctcatttat caaacgttgg ccataacccc aaatctcttc tgatagctga
     4501 tcaaaggtta tatactttag ctcatattgc tggataatgt tcattctaat cgactccatt
     4561 tattatcctg gtaaaattcg atatgacgta tttcgtcgta gtgaattttg tcttttccaa
     4621 cgtagatccc cagctcatca ctacctaaga tcttgccaat gatatcttct ggatagtatc
     4681 cttcagcgtt tcgttcttct ttttgaatag atactgatct attttttatg actgcagcgt
     4741 tcaatacttc cgcaatctct tcagtcgtca tttgttcttt tgctaaattt tgactggttc
     4801 gttgttcatt gtcggcatca atttcttcag tatgatcaga taaataaaac cctgcccact
     4861 ttaaacgtcc acgatcattg taatcaatca tttttaattc ccccatttcc gcccgcatga
     4921 ccaccaacaa gtgtgcttct agtaatgctt ctagcgcctt ctaacattga agaagcatgt
     4981 acaatcgacg taaaaccata tttttgccga atcttgtcaa taattttatc taaattttct
     5041 tcgtcaattt gcttttgtgg atcactaaat aaatccagct gaagcgaatc ggtgtacaca
     5101 agcttgctat aggttattcc aacatgcctt acttcttgtc cttcataata cttatcaaac
     5161 aagaaaagac aataattctg caattccttt gtattatctg tgatagggat cttcatctgg
     5221 tgtgaaaacc ctggtctcgt ttctaagatc gacgtgccaa tgtgtaaatg gacacaacct
     5281 gttttacagt tatgctgcct aatgcgtatc gctacttgtt ccgccatttc ttttaccacc
     5341 agctcgattt catttcttct agtataatct cgtggtaaca cttgtgaatt tccatatgat
     5401 ttttcctttg tcggttctgg tgggattgct atatctgttc gatcgatccc attagcatgg
     5461 aagtacagct gtaagccaat cacacctagt ctattcttaa tcgtataagg attccagtta
     5521 gcaagatctc taatgctcat aatccccatc tgattgagtc tttttttcat tcgagagcca
     5581 attccccaaa agtccgtcat ttcaggaata ttccatactt tttcaggaac gttttcgtac
     5641 gtccattccg caacaaatcc ttcattatgc tttgcttcgt tgtctaaggc tagtttagcc
     5701 aaaaggggat tatctccgac acctactgta gcaatcaatc ctagctcttc tttaatattc
     5761 tcctggatca tttgagccag cttctttctc cgttgacttc gtgttccttc agtcgtaaaa
     5821 agattcagtg atcgggtcac ttttaagatt gattcatcga tcgagtaaat cagtagatct
     5881 tcatcagcca catatcttct gaaaatatta tttacctgca tatttcgctt gatatatagg
     5941 ttcatacgtg gtggaacaac gtgtagtgtt ttaggaaatg gttgtggtaa gtcacgtggt
     6001 ctactcacat ttgtaatacc ataccgcttt tttgcttcag gagaagaagc taatatcaat
     6061 cctgaaccag tattatcagc tcgactcata acaacaagtt ctgttgttaa tggatctaaa
     6121 tttctttcta tacattcgac acttgcgtaa aagcttttca tatcgattaa aaagtaatca
     6181 tttactggct cttttgaata atccatcata aataacactc cattctttca cattatacaa
     6241 acatatgttc gatattgtaa agaagaaata gctaaataca taaaaaaaga agcataggta
     6301 tgctatcacc ctgcttcttc ttttgatttg tatgatcaat ttattctatc actttactaa
     6361 ttaatttgaa aatctaataa aaactctcac tctaaaagag tgagagactg caaattagag
     6421 tacggacttt tttggagttc cgttctttaa tattaacaaa tgaataaaat ccttacaaca
     6481 tttgagaata agttatcagt agacacttac aaaaaattct catactattt cctccatcat
     6541 tagtttttgt ctatataagg tttaccctaa atagacactg gtataacatt gaaaaatatg
     6601 gcttcctcgt gtatgattag ggtgtatttt aaatagttgc agaaagtagg taaaagtttt
     6661 gagagttgca tacatacgtg tctcatcgat cgatcaaaat gaacaacgcc agattgaaga
     6721 aatgaaaaaa ttcggtgcag agagaatttt catcgagaaa caatctggcg caacgattac
     6781 tcatcgacct gttttccaag aagcattaga ttacgtccga gatcaagata tttttattgt
     6841 ggaagctatt gatcgacttg gaagaaatta tgacgagatc atcgcttcag tcaattactt
     6901 gaagaagaaa aatgtgaagc tgatcattac tagtttaccg atcatggctg aagcaattgg
     6961 caatcctctc ctggataaat tcattaagga tctgatcatc caaattttgg ccatgatcgc
     7021 tgaacaagaa cggactgaat cgaaacgtcg ccaggcacaa ggaattaaga tcgcaaaagc
     7081 aaacggcgtc tacaaagggc ggcccaaatt atacagtgca gacgcaaaag atccccaacg
     7141 tcgccttgtt tacaaaagca tcgttgaaga tcttaaaaat ggtgttgcga ttgctaagat
     7201 tgctaaagac tacaatgtta cgagacaaac cgtgtataga ataaaaaaag acagcatggt
     7261 caatgacaaa tagttgatca tgctgctttt attatcttct catctttaat ttcctacata
     7321 taattactat ctataaaatt aagtcttact cagaacagat aaagcataaa attccaacaa
     7381 accatttttt acttaactaa ataaagagtc tgttaatata atcttcactt atttacgtta
     7441 atcccctact gtatttgttg gttccttatc tatattttct acaaaatcct tattatcttg
     7501 tgatttagct tcgtataatt ctttgtatgt cgacacattg gttatactaa ttcctatagc
     7561 tagttcttga gactctactt ttctctctag ctcctttgac aaagtgattt gagatttatt
     7621 tggttccgtt ggagtcaatt ctatagattc ttcataaaaa tctctataca taaagctatc
     7681 cctgaataat tcatagcttt aattctttgg cacattttat tgaaatatgt atcactaata
     7741 tccctatcaa ctgattttga ctaaaaagtt acttcaaaca ttcactgttc aaaaatattg
     7801 aggaataaat tttgggtgta aggcattttg agcatacttc tccctggata acttcccagt
     7861 aaaaaaatcg ttagattgtt ggattagatc cattgactgg ctcgcctcag gcgagcaaag
     7921 accctgtaga attcattctg atacacatga taactagata atttgagata gactcgtcta
     7981 cccgtttgga ctaatttccc agcaactttc agaaacttca atcgaataga atgaatggtc
     8041 attccctttt ggacttcttc aaagccaatc gttcttaaga agttgactaa gttgtaagct
     8101 atcaagctga gcatcattcg gacatgattc tccaaaaagc gaggactgtc tgttttgtca
     8161 aagtaaaagc cagctttcgc ttctttaatg aagttctcca ttgtgccacg tttggcatag
     8221 atagaaaaga tggtatcagg agaaacattt tctgatagat tcgtcacgat aaattcatgt
     8281 cgaaagagta gttcgcccgc ttcacgtgtt gagcgtatac acacgcgacg actttgtgac
     8341 caggattgtg cttgataagt ggtcgagaag tactgaactt ctcgttcttc ccacttttga
     8401 ttatcgccat aaagtactga tttctcagct atttgaccta gtctacgatt attcttcagt
     8461 cgaataacat aatgactctt ttttgattca cacgaatcat acacaccagg tgtagcgaac
     8521 ccgctgtctc cacgaaccaa gatgtcagtg tttggtagag agtgattata gtgctctaat
     8581 aaaggtgtga gaaactcctt tacgcctttt gatgtatatt gatttcctga acgtagttca
     8641 gcttttaaga agtcaccagt caatccgtca aaagctacca atggatggta accataggtt
     8701 tggtagtgtg tattataatt cgtttgttct tggtgaccaa atgtatctga atgggtcgaa
     8761 tctaaatcaa tgattaattc cgtatcatta cggatgaggc gtgctttatc gataagttct
     8821 tggttcaaag cttgaagttc atggatattc tcctcagata gtcgatctaa aaatcgggaa
     8881 agtgaagatt gagaagcgag ttctttccta tctaaaacag ctttaaacac aggatcttgt
     8941 ctcaggagat tagctgcaga atcagctgag taaccagcaa ttaattgcat aatgaactgc
     9001 tcaagtatgg ataagttgtc atgagtaaaa tacgctcgtt cgtcttcaat gtgaatgtgt
     9061 tgcttagcca gttcagaaaa accaaagatg ttcatcagct ctttcactag gacgagaccc
     9121 gaatcactcg ataattgacc acctgtatga gaaatagtga tatttgaatt gaattttact
     9181 tggtttttgt gtaagctagt catgaaaaga actcctttct tttggttggt ttagtcactt
     9241 taaccatagc agaaaggggt tcttttttca tcacttaacg ggtgaagatg aaaaagtaat
     9301 tgtaagctgc cgtgaggcag tttcacatgg ttttaattaa aagtatgaat tattcaggct
     9361 atcattaatt ttataaaaaa aattaaatgt ttttagcact gccatataac attcaaaaca
     9421 ttcttctata gttggtttac ttccttgagg agaatgaacc aatttattac gtttttctat
     9481 gaaattttta atttcctttc ttatttcttt cggaaactca atattaaagt accctttaaa
     9541 catgctccct aataatttgt ctacaggggg agattgtaaa ttctcaaata ttagagttaa
     9601 atcaggtttc tcttgttgat aaaattcctt tacccctatt tcacaggctg taattatcga
     9661 aataaaccta tctctagtat ttgatatatt tttacttctt ttaaggagta taagagaaaa
     9721 ggggatactt tcgtgtccat gcatgtaatt aactaattgt tgagcttcag aagttatatc
     9781 tctaattata tagttaacgg aattaggaag tgtctttaac tctaatgaaa tttctatcca
     9841 attactatct tctaatctgt atatgctcga agtataattt gattcgtcag caagcatcgc
     9901 tacatcccaa acactgatca taaaatcttt taaacgttca atcatttcag caatattgct
     9961 aaaatcagct aatttttctt tagaataaaa aaaaacattt atatcagaat caataaattc
    10021 tattttttta ttactatatc gtcatcatta tcttgaccat ttatgtttat tgttccctga
    10081 gtggggagta cttctttcaa attcaagtta aatttatatt ccattacttc tcctccaata
    10141 tataaaaatt acttaactgt atccaaattt aatatgtaaa taaatcatta atttttagct
    10201 aaattctatg agaagtttat ttttgttgtt tttgctaatt aactaaaact agtacaaaaa
    10261 atttaaaata gattattaaa cctattgctt attctattca gtcatatata taagcgtcat
    10321 cctttagtaa ctaacatccc acactacaat agtattataa catatctatt caacttcaaa
    10381 ttgttgaaat ttaagccatt tatatttact tttcctcaac tttagaaatg attttactaa
    10441 ccttatatcc gtaatacgcg taacaaacac attcattaat aacaatcaac actaagctat
    10501 attagctttt taaatgacta gggtaaataa aataaggatc aaaaactttt aagtttctga
    10561 ccctttcctt acttccgatt ggttaatagt gatcttttgc agaataaata aatatcgttt
    10621 cattttcaac tctatatatc agtctatgtt catctgtaat tcttctggac cattttccag
    10681 ataaatcatg ctttaatggc tcaggttttc ctaatccagc aaagggggaa cgatcgatat
    10741 cttttattaa cttgttaatc ttttttatat tgcttttgtt tccttgctca tgccaataaa
    10801 gataatcatc ccaagcatca tcagaccaag ccttaatcat cagattcaac ctcgattaag
    10861 tcatgtgttt taaatgcacc tttggagaat tgttcatctc ctcgacgaat tttttccatg
    10921 acgtaattat tagaaagtgt tctcaacgtt tcttgcatag aatcataatc tctttttgat
    10981 aatacaacaa ctgtatcttc tacatcttta cttgttacaa taagtgtttc agcatcctca
    11041 ttaacttgtt tcatataact acgtaaattt tggcggaaat ttgaataagc tactgcttcc
    11101 attcctttca ccccttattt atttctataa aacaattgta cattatattg tacaattaag
    11161 caaatgatta atattctaac ttcttataat taaaagtgct atcactttta gtttttagga
    11221 taaaaagtga cgtcactttt tgagtgctgg tacctcaaat cctgcttttt cttgggcaat
    11281 caataaatct aacgcaatac acataatcct ggattcactt ttgccgtact tctgctttag
    11341 ttgctgcaat tctttttgtc tcttttcatc caacgtaacg ggtaaccgtt tatttcctat
    11401 tgcaattggc attagtactc tctcctttca tcgaaataac cctatgaaaa atatggctgc
    11461 aatcatcttg aatagtagac tcacaagggc taatacaaag cgccaaaaga tcaaacaaaa
    11521 taccagtatt gccaaaaata ctacgaagtt taaatgcaca gctgcagcat ggcgcataag
    11581 tatttcgcca acaaatagga ctaacaatag aggaatgatt ttattcatat ggatctcctt
    11641 ctttctctta ggttatcggg tgttgcccgc ttatttcgca ccacctaagc ggcgggggcg
    11701 gttggagcga ttggtgcgaa ataagaacca ttcccttagt tactaggttt tttgtcctta
    11761 tttcacacat tctcactttt cggtataaat gattattgcc tttttttcct ttcaaatcgt
    11821 tgatatggca ttcgtttacg gtcaagttca ttttggattt cttctgtatc gtcgtaagta
    11881 taggtgtcta aaaaatcagt taaagtcgtg taccagtcgt cgcctgggtt atctacttct
    11941 tctacatatt ccctcaaaaa tgcttcgggt acagcgagtt cataatccat tcccattaac
    12001 acgatagatt ccgttccaca cgtcaaaaat ctagtaaata caaggtaata atcgtctatc
    12061 gtcgcatctt tgctgtttag ctcttccatt tcttcttcca ttaattccat gctctcaaaa
    12121 attgaataat attctgattc tgagtaatag tgtttcctgc aaatcgtgta gctgacaaag
    12181 ttttcgacca gctcactcct ttctaggtaa acattcatga tgtatttttc tgtttctagt
    12241 cgtagaagct ccgttccttt ttttaccgtt tcaggacgac gtttatacac gtctaaacga
    12301 ttatggctga ctgtgacctt cgtttgactc gtttcacttt ccaaatacaa ttgttcttc
//
LOCUS       DBBGSP010000083        12144 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000083 DBBGSP010000000
VERSION     DBBGSP010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12144
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.083"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..566
                     /locus_tag="ACIZE9_002728"
     CDS             <1..566
                     /locus_tag="ACIZE9_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGC6094537.1"
                     /translation="YFKSEKDTSSLTLTLEEGVEPDKVTSKVINQLKEKGSLKHLGEY
                     EVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRA
                     LGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVG
                     VSSVIGLVFSVMPASEAAKKDLIDILR"
     gene            967..1572
                     /gene="fic"
                     /locus_tag="ACIZE9_002729"
     CDS             967..1572
                     /gene="fic"
                     /locus_tag="ACIZE9_002729"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HGC6094538.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1588..2160
                     /locus_tag="ACIZE9_002730"
     CDS             1588..2160
                     /locus_tag="ACIZE9_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6094539.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2412..2669)
                     /locus_tag="ACIZE9_002731"
     CDS             complement(2412..2669)
                     /locus_tag="ACIZE9_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094540.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2795..3610)
                     /locus_tag="ACIZE9_002732"
     CDS             complement(2795..3610)
                     /locus_tag="ACIZE9_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094541.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            4127..5452
                     /locus_tag="ACIZE9_002733"
     CDS             4127..5452
                     /locus_tag="ACIZE9_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HGC6094542.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5445..5795
                     /locus_tag="ACIZE9_002734"
     CDS             5445..5795
                     /locus_tag="ACIZE9_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094543.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            5777..5962
                     /locus_tag="ACIZE9_002735"
     CDS             5777..5962
                     /locus_tag="ACIZE9_002735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094544.1"
                     /translation="MGSIRMNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSF
                     YVEAAAGYHKYEYYIGY"
     gene            complement(6866..7141)
                     /gene="prgO"
                     /locus_tag="ACIZE9_002736"
     CDS             complement(6866..7141)
                     /gene="prgO"
                     /locus_tag="ACIZE9_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="HGC6094545.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(7113..8066)
                     /locus_tag="ACIZE9_002737"
     CDS             complement(7113..8066)
                     /locus_tag="ACIZE9_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6094546.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            8678..10171
                     /locus_tag="ACIZE9_002738"
     CDS             8678..10171
                     /locus_tag="ACIZE9_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HGC6094547.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            10306..10602
                     /locus_tag="ACIZE9_002739"
     CDS             10306..10602
                     /locus_tag="ACIZE9_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HGC6094548.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            10703..11554
                     /locus_tag="ACIZE9_002740"
     CDS             10703..11554
                     /locus_tag="ACIZE9_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094549.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11575..11787
                     /locus_tag="ACIZE9_002741"
     CDS             11575..11787
                     /locus_tag="ACIZE9_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094550.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         4171 a         1864 c         2268 g         3841 t
ORIGIN      
        1 attattttaa gtctgaaaag gatacatcgt ctctaacgtt aactttagag gaaggagttg
       61 aacctgacaa ggtgacctct aaagtgataa accaattgaa agaaaaaggt agtttgaaac
      121 atttggggga atatgaagtg ttagatacgg ctatgttaac gaaaggaatt ggtcaaatcc
      181 tcagtacgat cacttatttt ataacagctg tagcaggtat atctttattt atcgcagggg
      241 taggtgtaat gaacatgatg tatatatctg tatctgaacg aacaaaagag atcggtataa
      301 gaagagccct aggagctact cgaaaatcga ttatgctgca gttcctttta gaaggtttga
      361 ttttaactct ttcaggaggg ttaattggct atttattagg aatggctctt gcttatagtg
      421 ttggttcttt gataaaggta aacgtgtcac ttgatctatt tactatttta ctagcggttg
      481 gggtatcttc ggttattgga ctggtctttt ctgtaatgcc cgcttcagag gctgcaaaaa
      541 aagatttaat tgatattctt agataaaatc agaatgacaa gaatatttac gttctagatt
      601 ctaaaataaa acacaaagag accaaccagg caccctattg tttctttgta gtatagagat
      661 attctttggc ttgtaagaga tcaatagagt taggtgaccg gagttcgaaa taaaggaaat
      721 ttttgattgt ataggagaat tctttatccc taatatttag aattttgagt atgccatgtt
      781 gatgttttag attctctata aatatagagg tgtatcaaag gtcaactaga ctgtgcaaaa
      841 tagagacact tgaaaaatct atcgggggtc agaaacttaa tagtttttga cacataaaca
      901 aaatcgcgat ataatggggt tgagagtgtt tcataaactt atgtcataaa gttaaggaga
      961 tttcgcatga ttttagagaa taaattggga ttaaccaatc aagttgagtt ggctaaggtt
     1021 gaagaaaaac tcagtaaaca aaaagcgaaa gaattgtacg attgtggaaa aataaatgaa
     1081 atcgaagttg gtacatttaa aggtttatct gaaattcatg aatttctatt ttcggatatt
     1141 tacgattttg ccggaaaaat ccgatcggtc aatattgcaa aaggaaattt tcgatttgca
     1201 ccagttatgt atttagaaca ttcgttacag catattgatc agatgccaca aacttctttt
     1261 gaagagatta tcaagaaata tgtggagatg aatatcgctc acccatttcg agaaggaaat
     1321 ggccgaagta ctagaatttg gctggatctc attttaaagg aagaattgca aaaagttgta
     1381 gattggaact taatcgataa agcagactat ctttctgcaa tggagcgaag tcccataaac
     1441 gatttggaaa tacgctatct aatttccaat gctctgactg ataaaattga cgatcgcgag
     1501 ttatatatga aaggaatcga tgtcagctat ttctatgaag ggtattctga gtatacgata
     1561 gatgatttgt aaaagtaggt ggaccaaatg acgaaatatg gatatgcacg tgtctcaacc
     1621 gcttctcaaa gtacaaaaga acaaattcaa cagttgcttg agaacggcgt agagaagaag
     1681 aatatttttt cagaaaaatt tacgggtaca aaacgggatc ggccaaaatt caatcagctg
     1741 ttggctggtc tgaagcctgg agatgaaata gttgttacga agcttgatcg atttgctcgt
     1801 aacacgagag aagcattaga gatcattgaa cctttactcg atgataacgt aacgatcaag
     1861 gttttgaatc taggaacgat tgaaaatacg tccatggggc gaatggtgac acggacgttg
     1921 ttgagtgtag cagaaatgga acgtgatatg attgtggaac gtacccaaga aggaaaaatg
     1981 tttgcaagaa agaataatcc taatttcaga gaaggacgtc cgaaagcaac aatcacaccg
     2041 aagaagaggc acgcatatga actgcttact tcaggtaaat cgtataagga agttgaagct
     2101 ataaccggtt tcagtcgcag tacgcttttt agaataaaga agaaaattga agaaagttaa
     2161 aaaagaagtc tcagcgaacc agacaggtaa atacttaatg cgttctagat atgagtctat
     2221 tagcatgttg tgaaatataa tattttttta tttacttgat ttctgctcaa aaaatgtgta
     2281 tggtaactgt aaaaggtaaa gtaattaaag gtatgctagc cacgcttact atattaggat
     2341 accatcatat atttataatg aacgatttgt tcgtctacca aacaacacat atcgttcagc
     2401 gtaagtcacg tttaggaacg tggctttttt agtgttatta tcgataaata atctattgac
     2461 tctattgatt ttatctccat atccctacgg tgttgattgt ctttagatct ttcatttaag
     2521 aaccaaataa ctatcataaa aatcagcact gctgctaata taataaacag cattcctatt
     2581 gtgatattac ctattgattt taccataact acgattaaag taataatggc attcaagtct
     2641 cctttgttct ctatatataa attagccata aatcatcttc ctttcaaatt aagatacttg
     2701 tttgatacca ataaatagta agcgtggcta gcataccttt ttctgtaata gcaagtgttc
     2761 taatagtcca aacttaatga tggaccgatg ctagttatag tacagtaatg ttttctttct
     2821 tatctagatt tttagtaagc tctatcagca aatctaacaa atctgagtcc ttttcagaaa
     2881 ctaaattaaa tctagtgttt acaacaaagt tttcatgttc tatattgttt agattatttg
     2941 cggaaaggag ggcttctaga tcttgacatt caaatctata tgcatcgtca taaatcttac
     3001 tagaaggagt gcttaattcg aaattactta ttttctcatc ttggaccaag ataaatttat
     3061 agatagtatc tttttgtgtt tttcttttaa aaacacaaca gagtgtgtta taaggaacgt
     3121 tataattttc atcagcctca ttttttctcc attcaaacaa atgataaact gcaaccaagt
     3181 tgccatcaat ttcatggaca gtgctctcgg taacatcctt taaagaacta tcaagggcta
     3241 atttatagta actagagaga ggaagtaaaa ttgtcgattt actgagatgg ttatcgtcta
     3301 tacgtgcaat catacctaaa tcaactaagg ttttattcca ggtgtttata gttttagttg
     3361 tcactcctag agactctgct atggtattga ccgaatgcca ggaatccccg ccttcattct
     3421 ttgccttaaa acagtaatac agatataaat taatagcttt gttattcggt aaatattttt
     3481 caagttctgt tggtagaata aagtaagaat ccttaatgtt ttttctgaac tgtctccagt
     3541 ctctgtagtt ttgtttataa agttgtgaaa cggtttttcc acctttagaa agtcctgcta
     3601 tcttaaccaa tcttattgct cctttcttga atctgtcatg atcatacagt attttttact
     3661 tgtagtccag caccttaata tattatccta tgtaattaat ttcgtactag atagtaatta
     3721 ttttttattt aattctctag tcacttacaa ataagttata taaactacga ttaataaatt
     3781 attacaaaaa ctattaagaa aacttctaca tacaactatt acaaaactat taagaaactg
     3841 aatactccta ttttttgttt ttaaggaaag ttttttcttt tttgaatttc ttattttttt
     3901 ctaatataac taagcaaaac tggataatac gacacttatt ttcaaatttt cacaagacta
     3961 atagtaaata tccatttaat aaagtgatac aatgtgttga ttttacaaat caacagaaga
     4021 agtagggaaa taacttacct atgcttcttt ttttgtacat ttaatcgatt cttctttaca
     4081 aaaacgaacg tatgtttgta taatgtggaa gaatggagtg ttatttatga tggattattc
     4141 aaaagagcca gtaaatgatt actttttgat cgatatgaaa agcttttacg caagtgtcga
     4201 atgtatagaa aggaatttag atccattaac gactgaatta gtcgtcatga gtcgagcgga
     4261 taatacagga tcagggttga ttttagcttc ttcaccagct gcaaagaaga agtacggtat
     4321 ttctaatgtc agtcgaccac gagatctacc gcaacctttt cctaaaacgt tacatgtcgt
     4381 tccaccacgc atgaatctct atattaagcg aaatatgcag gtaaacaata ttttcagaag
     4441 gtatgtagca gacgaagatt tattgattta ctcgatcgat gaatcgatct taaaagtgac
     4501 cagatcaatg aatcttttta cgactgaagg aacaagaagt caacggagaa agaagctggc
     4561 tcaaatgatc caggagaata ttaaagaaga gctaggattg cttgctacag taggtgtcgg
     4621 agataatccc ttattagcta aacttgcttt agacaatgaa gcaaaacata atgatggatt
     4681 ccttgctgaa tggacgtatc aaaatgttcc tgataaagta tggaatattc ctgaaatgac
     4741 agacctttgg ggtattggat ctcgaatgaa aaaaagactc aaccaaattg gtatcatgag
     4801 tattaaagac ttagctaatt ggaatccata cactattaag agccatttag gtgtgattgg
     4861 cttacagctg tattttcatg cgaacgggat cgatcgaaca gatatagcga tcccaccaga
     4921 accgacaaag gaaaaatcat atggtaattc acaagtgtta ccacgagatt ataccaggag
     4981 aaatgaaatc gaactggtgg taaaagaaat ggcggaacaa gtagctattc gtatcaggca
     5041 acataactgt aaaacaggtt gtgtccattt atacattggc acgtcgatct tagaaacgag
     5101 accaggtttt tcacaccaga tgaagatccc tataacagat aatacaaagg aattgcagaa
     5161 ttactgtctt ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc acgttggaat
     5221 aacctatagc aagcttgtgt acactgattc gcttcagctg gatttattta gtgatccaca
     5281 aaagcaaatt gacgaagaaa atttagataa aattattgac aagattcggc aaaaatatgg
     5341 ttttacgtcg attgtacatg cttcttctat gttagaaggc gctcgtagta ttactagaag
     5401 tacattggtt ggtggccatg caggcggcgc aggagggctt aaaaatgatt gattataatg
     5461 atcgtggacg tttaaagtgg gcaggttttt atttatctga tcatactgaa aaaattgatg
     5521 ccgacaatga acaacgagcc aatcaaaatt tggcaaaaga acaaatgacg actgaagagg
     5581 ttgcggaagt attgaacgct gcagtcataa aaaatagatc agtatgtatt caaaaagaag
     5641 aacgaaacgc tgaaggatac tatccagaag atattgttag caagatctta ggtagtgatg
     5701 agctggggat ctacgttgga aaaaacaaag ttcactacga cgaaatacgt catatcgaat
     5761 tttaccagga taataaatgg ggtcgattag aatgaacatt atccagcaat atgagctaaa
     5821 gtatataacc tttgatcagc tatcagaaga gatttggggt tatggccagc gtttgataaa
     5881 tgaggttggt gttgaacgct tctctttcta tgtagaagct gcagcaggat accataaata
     5941 cgaatactat attggctatt aaagtgcaat aaaattatat ttcttttatg ttttacattt
     6001 tgtatcaatt ctgataaaat tacctatagg taattaaaaa atataaaaaa actagttaca
     6061 accttaggac gttgtaacta gcttgaagca tactagagct aactaaaata gcactagaaa
     6121 gcaatgttaa acccgtccaa caaacttgat ttaacattga gaccagctta ttcagctaaa
     6181 tatagttgaa taagcttctt ttgttttaaa aaaacaaaag gtgtactacg aataacgcaa
     6241 gtaaaagaaa tactattaca accagtaggc tacaagtaag tattactaaa cattgcgtag
     6301 ttagaacctt tgctctattg tctaaagcca caaaattaga gatcagcttt atgatgctaa
     6361 gagcgagctg catccatgcg gacataggtt cttttgacac tattaattct cctttttagg
     6421 ataagggaaa ttgctagtag ttttttcatt agcaccatcc cccttcattt gattgagtct
     6481 agtgctgctg tgatagtttg ctgtttaata tgcttacatt cttattataa cataaatgaa
     6541 acaaacacat ggttagaggt cgtatcaatc aaaatagtgt ctcacaaacg atttattact
     6601 tactcctgct gactaacgga ctgttcttca gtaactgtaa ctatatgttt gttaaaacca
     6661 ccattacctg tagataaaaa ccaatatatt tactatactc actatattaa atatatttag
     6721 tatagtaaaa actagaaaca ataaaatttg tgaatgttgt atacccccaa acaatacaca
     6781 tattttgaag gattaggatt aataaagcta aaaatatagt aagtatacta aatatattta
     6841 ctatatctag tatacttact atattttaat cttttgatcg tctattatat ataatccgtt
     6901 cctcgtcgtt taaagtatca acataggcgt ccattgcaag tttgactatt tcatacatag
     6961 gaatatcttt tgcataacta agatcccgaa tggtttttag tacgggagga tctacttgaa
     7021 ctggttttct ttctttcgca gtgtactttc gttcccctaa ctcgacatta atatcatctt
     7081 taattgaaat atcttcagca ccaattttct tcttatcttt gttcgttggt aataatgcca
     7141 tttagtttaa tctcctttcc aagaggtagg atatgattgg ccattgagtc agcatattta
     7201 ggtgtataat caaatccttc aatatcacca tgttgttcat agtattcaat tctttcttct
     7261 aattctgtaa agatgtctgc aaaaatagcc caccatcttc gatctacata atcatttaat
     7321 tggataccat tctcaccata catttctaac cgatccgagc ctttaacaat gcttttaaaa
     7381 atgtttgatt caccatactt atcaattgtt ttttgatagt ttgcgtgttg agaggaacgt
     7441 cgcactgaga aaagaacagg caaaattcca atgatttgaa gatgagactc ttcaaaattc
     7501 gtgacaatcg gaactaaaac tttattaata aaatcttctg ttccttccat tgcgtaccgt
     7561 tttaattctt gcattgcaat aatataatct gcagcagtta agaatgcacg aaccacatta
     7621 tctgttgatg gtgggcagtc gataaagata taatcgaaat tttttctcaa ttcttctaaa
     7681 ggtttaatga aggccaatga tctcttacga cgatcaggat atttttcgga caagtattca
     7741 ttaagttctt cagatccagg agagccagcc ataatatata aatgtggact tacttgagta
     7801 atacctgaaa cccagtcccc ttttttgatt gctgcagaca tggatcgatc aaagctagta
     7861 atttgatacg ttgatccaat gttggaagta gtatttcttt gttggtcata atcaattagc
     7921 aacacgtctt tttcaaaaag ttgactagaa acaatcgcta ataaatcatt gtctgtagtc
     7981 ttaccaatgc cgccttttct acctgtaagc attacaactt ttcctagttt atctgatgtt
     8041 ttaaatgcag tccgtaagtt ttccatagtt ccctccaatt tcctatacta aatatattta
     8101 gtatacttca tatacttaat atattcgata tatctaatat actccaaatt gataagaatt
     8161 cagactttat aaggaatata gtggatatac taaatatatt tgctatattc agtatatcag
     8221 atatattcaa aatgtcaaaa tatatttgtg cgttttgcgt tgacaattta gagtgaaaag
     8281 aggtaaactt aattctatag aaaccacaga taattcacta tttacaaagt agcaaaagca
     8341 gtggtactct ttaaacagaa aaattacata aaaaaaagag acggaaataa ttgattttag
     8401 cagaatcaat tatttctgaa tcacatggtt aggacatgtg ttcacgctcg tctcaagaat
     8461 atgtaagtag ctaccaacta cttatattaa aagttgatcg gatacctttt ccgattgcct
     8521 ttattctacc aaaaaaaggc gagcaactca acagaagaac gtttatttag tgtacttaaa
     8581 ttaaatattc ttaaacactg aagagagaac acatactatg gctgagatta aagctaaact
     8641 gtgttctctt tttgtttgag aaaggacgtt acaatcgatg ttgagcgaaa tttattcagc
     8701 tattcttaaa aacggcttac gtacatacaa atatcgaaac agcaccatga aacctgcagg
     8761 tcatattgat tccagtagga gtggtgctat ctttgcgtac cgtagcaagc aattaatgaa
     8821 tgttgggcgt ggtatggtca ttacttcgga agaagctatt ttagagaacg aaaagaaact
     8881 aacgcattgg acacctaata cctatcgctt tggtacttat gcggatgatt atcgaacagt
     8941 ggttaaaggt cattctgaga aaaacttaag tcaaatcaac acatttgtag ttgatatcga
     9001 ttcaaaagag aaccatcaag gcgaaattat tttagcctgt ttagatcaag tgggctacat
     9061 gccaacgcta attttagaat cagatcatgg ttatcaagtt tattttgtac taaagacacc
     9121 aggctatgtc acaaagaaaa gcaatttcaa ggtgatcgat gtagcaaaaa aaatttcaaa
     9181 aacaattcgt ctacagttgg ctgaaaaatt gtccggagtg gatctaggat gtaaccactt
     9241 cggaattgct cgattcccac aagaaaataa tattgttttt aaagaaatga actatcagta
     9301 ttcttttgct gactggattc aatggtcgat gaagcttgaa tcagatcaaa aaacaaaaga
     9361 agatcgagaa cgaaaactaa ttgtctttcc tgagaaaaaa gaaattcgtc aagtagatga
     9421 accgtggttc gatatgttac ttcataaagc aaacatcgtc ggcggagaag gacgtcttgg
     9481 tcgaaataat gtgattttca cgctttcttt agcttattac tcttcaggtt atgcattgga
     9541 tacttgcgaa tacaatatgt tcacattcaa cgaacggtta caggaaccgc tatctgaagc
     9601 agaattagta aagattgtac gtagtgctta ttctggtaat tatcaagcag caagcagaga
     9661 attcattatt gaattgtgcc agcaatgggt ttcaccaacc ttaaaaaata atgatctgtt
     9721 cattcaacga cgtggctggt ggaaatttaa aaagccacga gatcaaagaa aatatagtca
     9781 taaaaatgaa tggaaagaag atctattggc ttatctaagc gaaaaaagtc ttgctagtga
     9841 gccttatttg aacctgtcaa aaaaagaatt ggcttcacaa ctaacgatgc ccaagcgaac
     9901 acttgataag atcttaaatg agttacgaga ggagaataaa gtcttctaca aggtaacacg
     9961 aggaagaaat ggcggaatga tcattgcttc agtcaaaacg ttgttcgcga gggttattca
    10021 actaagtaaa gaaaagagac tagattattc aacaaggatc acagaggtat ttggactcaa
    10081 cgagagctta gtagaagaga catttagaca attatcaacc cccttgaacc ctcttaaaga
    10141 agtgaatctt tttgaagtag atacaggttg aaaaataaaa ggtgcaaatt gccttataca
    10201 atatatctat gatacttctg taggtgttgc tccctttgcc tagctacgtg taggtggtat
    10261 acttataact gcgtatgcag tcttatgtat catggaggaa gttgtatgtc gttaaaaaat
    10321 tatgtctatt cacatcctgt taatgtgttt atcattggtc gtttgggatt atctgtggaa
    10381 gtgttctgtg agctttatgg ttttaagcag gggactttgt cttcttgggt taccagggaa
    10441 aaaacagttg cttctttgcc gattgagttt cttcatgggt tgtccttagc ttctggggag
    10501 actatggatc aggtatatga ttgtttgtgt gtgttagagc aggagtatat tgagtataaa
    10561 atagctaacg agttaagaaa aaggaagaag tatatccagt agtagttttt atttacttaa
    10621 aaaattggtt cattgagcaa cctatcgctg ctaaagtagc aaaggaaaac gttaaaggaa
    10681 agaatttagg gaagaaatcg aaatgaaatc ggacgactgg attgaacaca cctggcttcc
    10741 tctgaaaaga aatagcaaac gaaagaaatt ttgggtattg caattatggc cattaggaaa
    10801 actttgtagt tacggggcac gacttattct tgatttaacc gtttactcga ttggagtatt
    10861 tggaacggct tattacttga taaatgatcc caataggatt gcagcatcag acatttttac
    10921 agtgctaatg acgttgattt ttgtcatgct attgtctatt tttactcaat tagtcatgca
    10981 atttaccagg caaaaattaa cagcaggaaa acttttcaaa agcctattcg atttaattgt
    11041 tgtaaatgca attctagcga ctttaataaa acaaattgaa caatctggaa gaacaacaaa
    11101 aggagtgaag gattttttat tgacgtttat tcactttgta aatggacaca tgtatttgtt
    11161 tgaagtgggt attattctct tttttgtcgg gtatgtatcc acgaaactta ttaaacgttc
    11221 aattgaaaaa gaaattgaaa ttgacctgat tccgacactt cttggttatg agtacaatgt
    11281 tgattttgga agatatgacg aattgatcaa tacggatatc gttcacacga gtatccatga
    11341 atctactgtt aagggcatca gatctatttt aaaaaatggc caggaaatga aagcaataga
    11401 tcgaagaaaa gagatctaca atttttatga agtcgaagca agcctacgat atggcatcgg
    11461 aaaattgtgg ttagatggaa gtaatattcg tcaaaacaaa ccatacattt tttggaacag
    11521 tagtgattta gaacttccaa tgaaagataa ataattatgg agaatcgttt gaaaatgatt
    11581 cctctataca ggattgtgct tatagttggc atggagttaa aaaccttaaa gaaggagcag
    11641 ttattcaaag tgaaagaacg tcataatcag ttactatgta gtaaaacggg tacgatgaac
    11701 attgaatacc gaacagaata tttagaatta acgaatcaaa ctgatttttt gttgattcga
    11761 aagcaacaag agcaagaaaa aaattaatgg ctacttatag ccaattgatt gatgaatggg
    11821 aacaattcaa ggaatctaaa attccagaac gtctctaaaa gcctttattt gtaaagagca
    11881 taaggaaacg tgggaacact ttttaaaaaa agtgttccaa taggctgtgc ctattacgtt
    11941 tctcaaaaat aaatgtggga acaaaatatt taaaaatagg atagtgaaag gatagtgaag
    12001 gatagtaaaa ggagggtagt aggatagcaa aaaggatagg ctccttttcg ctatcctttt
    12061 taaattggag gaattaatat ggaagtaaga ataagaaatg tggatgagaa aatcgtaaga
    12121 gaaattgatc gaagatgtga cgaa
//
LOCUS       DBBGSP010000084        12040 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000084 DBBGSP010000000
VERSION     DBBGSP010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12040
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.084"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            104..1147
                     /locus_tag="ACIZE9_002742"
     CDS             104..1147
                     /locus_tag="ACIZE9_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HGC6094551.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
     gene            1320..1544
                     /locus_tag="ACIZE9_002743"
     CDS             1320..1544
                     /locus_tag="ACIZE9_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094552.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            1547..1804
                     /locus_tag="ACIZE9_002744"
     CDS             1547..1804
                     /locus_tag="ACIZE9_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094553.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            2021..2674
                     /locus_tag="ACIZE9_002745"
     CDS             2021..2674
                     /locus_tag="ACIZE9_002745"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094554.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSADCKIKLDN"
     gene            2737..3696
                     /locus_tag="ACIZE9_002746"
     CDS             2737..3696
                     /locus_tag="ACIZE9_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6094555.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDESFIQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
     gene            3752..3961
                     /locus_tag="ACIZE9_002747"
     CDS             3752..3961
                     /locus_tag="ACIZE9_002747"
                     /inference="COORDINATES: protein motif:HMM:NF040212.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5839 family protein"
                     /protein_id="HGC6094556.1"
                     /translation="MKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTV
                     TELYIAEKEDITKMKPVIKILDNKE"
     gene            3971..4765
                     /locus_tag="ACIZE9_002748"
     CDS             3971..4765
                     /locus_tag="ACIZE9_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094557.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            4794..5912
                     /locus_tag="ACIZE9_002749"
     CDS             4794..5912
                     /locus_tag="ACIZE9_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094558.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            5945..6235
                     /locus_tag="ACIZE9_002750"
     CDS             5945..6235
                     /locus_tag="ACIZE9_002750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094559.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFLLKNGKVLRT"
     gene            6519..7208
                     /locus_tag="ACIZE9_002751"
     CDS             6519..7208
                     /locus_tag="ACIZE9_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HGC6094560.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            7245..7412
                     /locus_tag="ACIZE9_002752"
     CDS             7245..7412
                     /locus_tag="ACIZE9_002752"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094561.1"
                     /translation="MVNEVETLLASFFENGHVNDEWRKEEPKRVNAYIARLKRFIDKY
                     KENSDKFSKDK"
     gene            7432..9060
                     /locus_tag="ACIZE9_002753"
     CDS             7432..9060
                     /locus_tag="ACIZE9_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094562.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMNLTIKRIYDLLSLI"
     gene            9111..9482
                     /locus_tag="ACIZE9_002754"
     CDS             9111..9482
                     /locus_tag="ACIZE9_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094563.1"
                     /translation="MRELTLSSKELEKKTALLNEIFSADCIIQSLKESSFSKLTDQEK
                     ISYMLSLDNLGTKYDESASSDKLLIELVSSLSSFGKMKRFNVILEIFAWLIPSFIWFF
                     YIFIVESELIAKVSLGLLIPI"
     gene            9567..9767
                     /locus_tag="ACIZE9_002755"
     CDS             9567..9767
                     /locus_tag="ACIZE9_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094564.1"
                     /translation="MLKRIAWDKDNKTDIELKEYKYNYFSRCIDRKLLFKKEGLEFSF
                     DEDEFEKLVMDWRKNLLDTVQF"
     gene            9901..11127
                     /locus_tag="ACIZE9_002756"
     CDS             9901..11127
                     /locus_tag="ACIZE9_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094565.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
BASE COUNT         4643 a         1527 c         2389 g         3481 t
ORIGIN      
        1 caacaacgat tatgatctta aaacaatcgt ttatgtaatt ggcaatctta cgaataattt
       61 tcatgcaata atgacaataa aaaatgaaaa ggggtaaaat caaatgaaaa aatttttagt
      121 aggaattcta ttcacaatgg ggctagtatt attatcacct tcagtttcag cagaaagctc
      181 tatttccatg tatcgtatgt ataatcccaa tagcggagag catctataca ctagaagcgt
      241 tggagaaaga gacaatctga aacgttatgg atggcattac gaaggtgtcg catggcaagc
      301 tccaacaagt ggtactcctg tttatcgttt gtataatcgg tataacggtg aacattttta
      361 cacagttgat gccggagaaa gagataagat ttcacacaca ggatggacgt acgaaggtgt
      421 tgcgttctat tcctacaacg gagcaaatag agttcctgta acacgtttat ataacaaata
      481 cgtgaattgg catcactaca cgttagatca aaatgaaaag aacgtaatta gtaaacaagg
      541 ttggaagatt gaaggtacag gctggtatgc aatgccaaac agcgtaccaa atcctacacc
      601 tgctccaagc actgaaaaag tgttgaacgt tcctgttgta tggcaaggaa atacaatgtt
      661 atgcgaagga gcttctttat tagaaggttt acactacaaa ggtgtagcca caaatcaaag
      721 cttaaccagt tttgtaaact atatgccaaa agctaatgac aataatcctt atcatggtta
      781 ctcaggagag tggcgtcata acgttaatgg aacgtatcaa ggcatgatgg ctgacccagt
      841 agttaaatgg gcaaaaaacg ttggcggtaa tgccgtcaat atcactggtt caggaacgaa
      901 tggaatcaag aatgaaattc gcaatggtaa tccggttgta acttggatta cttataacta
      961 tgctacgcca gagttcaaac aaatgccttg gggtcgtgca gtatggaatg gacatgtagt
     1021 tctcgtggat ggcttcagaa atggtgcata ccatgttgtt gaccctgtat ttggcgcaaa
     1081 atggatcaat gcaagcacgt atgagagagc atttaatgtg actggaatgg cggttgctgt
     1141 acgttaattg atagaattat caactaaatg aaataagagc ttaattactg aaatggtaaa
     1201 taggctctta tttttttaga ggaaattttt gtaatacgaa tctataacaa aaaatattga
     1261 atgtagtaca caaaagtggt atattaaaat cgtagagatt atgcgaagag gtgattttga
     1321 tgaaccaaag aagaagaaaa aggttagaag aaataagcga gcgactttcc gagctaaagg
     1381 atgagttaga agtaattcaa gaagaagagt acaaagaaaa tatacctaaa aatctacagg
     1441 gatcagaaag atatgaaaaa gcagaagaat ccgttgatca acttgaagaa gctgttgatg
     1501 gtttatccga catattagaa ttgattgaag atatagctag ctagagatga ttaatgaaga
     1561 tttcaggagt gagaataaaa tgattgatat ttcactgata gagaagctac ttttttcaaa
     1621 taagtacaca gccaaagagt tggctacaag atggcaaata tccgaatcag ctattaaagc
     1681 ctatcgtcaa aataagggaa gcgtaggatg gcgtgattgg aaaggaatca gcattggaaa
     1741 agcagaagac ataatgaaac gtgaaggatt tcaagctgac aatgattcta aaaaagttga
     1801 atagtttaat agtcgccaag aaaagtacca ggacgagggg aaaggtagat tacaaaggaa
     1861 aacactttta aataaacttc gcaaaagcat caggttatga gtggctaggg ctatacgaat
     1921 gtgatgaaaa caaagggctt taatgtcaaa gaaaacgcaa taggggggga acaaaatttt
     1981 taaaaaagat atttatgttt ggtttaatgg aaaaaaatat atgactacta acaaaaggtg
     2041 gtcagagcta gtacaaaata cagttaaaaa agtcatgcca gatggatatc atttcaacta
     2101 tatacaatgc tcacaaacaa ctgaaagtat ttatttttca atattaaatg agaatagact
     2161 ctattatttc agggtaagtt cacaccatag gaaaaagaga gaagataatg ttacgacatt
     2221 tttatcggga aaatacaatg gcttcaaaga gttaagtgaa gccattggtg agtatctaaa
     2281 aagtaataga tttgtcagaa tttctgacaa acatatattg atcttgttac tttatttgaa
     2341 taatagcttc aaattgtttt ggagagacga cactttctac tatattgaga acggcatgga
     2401 tatttattct ggtatcaacg gcatattaaa acattatatt aaggcgttac ttcgatatgg
     2461 ggttctttat caagaagatt taagtaacca aattaagatt agtaattctg gaaagtcatt
     2521 actggcaaaa tataaaaaat tgctttctcc tatctacaaa ggaatagata tggaagctgt
     2581 aaattctgaa actttattta atttagttgt tgatgaaaag tttgcgaatg aattttttaa
     2641 aagcgccgat tgtaaaatta agctagacaa ctaaaaaagt catttgtgct acactcaaaa
     2701 tagttccgtc caaagaatta taaggagtga gtacaaatga cctataccca tcttacaacg
     2761 gatgaacttg taatgataga gtcttatttc aaaataaatc aatctgttgc gaaaactgcg
     2821 catttcttga atcgttcaag acaaacgatc cataaagtat acctgttctt caagcaagga
     2881 aaatcagcct tagagtacta tcaacagtat aagaaaaaca aatcaaactg tggtagacgc
     2941 ccgcttgttt tacctgagga acaatcagaa tatattcaaa gaaaggttgt tcaaggatgg
     3001 acacccgatg tgattgttgg tcgtgcagcg tttcctattc gttgttctgc tcgtaccatt
     3061 tatcgtatgt tcaaaaaggg gctatttaat ccttctgact taccgatgaa aggcaagcgt
     3121 aaaccaaatg gacatcaaga aagacgtgga aaacaagctt tccgtcgctc tattcatgaa
     3181 cgtgaaaaag attatagcca attctcaaat gagtttggtc accttgaagg tgacactatc
     3241 gtaggtttga aacataaaag tgctgtaatt accttagttg agcgattatc aaaagttatc
     3301 atcacattga aaccgtgtgg tagacaagcg attgatattg aaaacaaatt aaatcattgg
     3361 tttgaatctg taccgaaaaa tctattcaaa tccatcactt ttgattgtgg aaaggaattt
     3421 tcaaattgga aacagatcag taatgccaat gatattgcca tttatttcgc tgatccagga
     3481 acgccgtctc aaagaggcct aaacgagaat tctaacggat tgttacgtag agatggttta
     3541 ttgaaatcta tggatttcaa ttcagtagat gaatctttta ttcaatctgt cgcatcgaaa
     3601 cgaaataata ttcctagaaa atcactgaat tatcgaacac ctttggaagt atttttgagt
     3661 tacgtaagta ttgatgattt gtctaactta atttgacaat taagaaagta aaaaaattga
     3721 aagactaaat aacctgtttc ctgaaaatgc aataaaagct tatgtagata ataataaatc
     3781 acgattatac aactggttta ttcccaaacg gttgcgagga aaaatcaaaa ttggcgatca
     3841 agtgaaagta attaatctaa atcatactaa gatcgttacc gtaacggagt tgtatatagc
     3901 tgaaaaagaa gatattacaa aaatgaaacc agttattaaa atactagata acaaagagtg
     3961 agtggaatat atggtagcaa aaaagaatac tctaaaagaa gcttctgaaa aatatcaaga
     4021 tatgaaaaga cgaggattaa taccaaagga caaaaaaggt atatggagag aatttgttaa
     4081 ggaagtcagt agtgatcgaa gtggcggtga ctttgttgga cgatatacag caaaaggtta
     4141 tagcaggcgc ttaaggatca ctgttgaata tggaacgaat gaatcagcta cagagctgaa
     4201 gcaaaggtac ttagatacac gaagagaagc ttcaaaaaaa tatgatgatt tcaagagcag
     4261 aggtctaatt cctaagaaga aaaaggggat ttggcgtgag tttttcaaag aagaagatag
     4321 caatcggaat aagggagact tcattggacg atacacagca aaaggctaca ctaagaattt
     4381 agggatcaag gttgaatacg gaactggtga aagttcatgg gaattgagaa atcgctattt
     4441 aaatacattg ttagagaaat ataaagcaga attattggag ttgttcgatg ttaatgattt
     4501 tatcgagatg gctgaaaagt atggtcatga agaaggtttt atgatcaatg acattatggt
     4561 tattgataat tttacggatt tattagcact tgcgaaaaaa gcaagggatt taagagaaac
     4621 gcagatgtat ctattcagaa ataaaaacgg aagaaaccgg agaactgaat cgagtgagat
     4681 tgaagattac tatgatgcct ttacacacga tctgggagcc tttgtagacg agataagtgg
     4741 tgtaatgaac aaatataggg tctagaataa aaaagccgga gatgagcaga taaatgggaa
     4801 acaatagcat atacacacct gaaatgcaga ataaaattaa aagacttgtc ggattagggt
     4861 ggatgacaag aggaaaatta gattctttta gtacgatcaa atatcttttg atggacattt
     4921 accgtcagaa caagcaaaca ggaatacatt ttttgggcta tgataagccg gaagatgcac
     4981 ctttctttgt tccaagttca gcctatagag ccagtacctc cggtagcatg tataacttgg
     5041 atttgtttga ggaaggagca aagatgatcg aatatgattt caacgaagcc tattcgagga
     5101 tcatgagaaa ttatcctttg ccgtcaaaca cttatttgaa agcaaaatat aatacagatc
     5161 aagctatttt gagagcgata aatagaccaa aagtaagacc gtatgaaaat ttaaaaacgt
     5221 atatgttctt tttggttaat tttgaaggaa cagccaaaga aggaacatat gctaatccaa
     5281 aatcacagtc gatgtttgcg gattatggcg aaaatcccaa aacagctaat gagcctattt
     5341 ggttatcgga gattgagcta acacttatcc ttgattatta tgatattaaa gagatggaag
     5401 tcctagatag ccacacattt ttgacgaaaa aaggattact caaagaatat tttgaaagaa
     5461 tcgagccatt aaaaactgat cctgatacgt tgaagcttta taaaaatctt agaacgaaag
     5521 tatttggtgc tatcggacaa aaatcattaa gagaaggaga aacaagcacc ttcgataaat
     5581 acagtatgta taatcgagcg tattcctcca tggtagcagg cgtatttaga gatcgtatgg
     5641 ttagatatga acagaaatac gttcatagcg catatgggct attaaaaatt cgtactgatg
     5701 gattgtattt cagatccgaa gtaccagagt ttgaagagct gtataaactt ggagtagtta
     5761 agaaaaaagt tcatacaata tccaaagaag aagtcgaaaa agctttagaa tttaaaaaca
     5821 aaggatttga aaataagggc tcctttggga aatctaaaga tgaagttaag ggtgttgtga
     5881 tagacgatga tttcgagttt gattttgact aaatactctt tggaaaagat ggtaggaggt
     5941 aaatatgaag aagaaaattg tggaaggaaa tgtaggtgtt attattctaa aagattcaac
     6001 tgactatgct aaatcaatgg cactaaaaga cgaaaaagtt gcacgcatgg ataaagattt
     6061 agttgaattt ctgatggatg atacagaaag attaaaaggg gatcagtttt tgagtttaat
     6121 gaaagacaaa ggcttaaaca catatggttt atttgattat aagaaattag ctatagagtg
     6181 ggtaaaagaa ggagaaatct ttttattgaa gaatgggaag gtactgagaa cttagttctt
     6241 catcagtatc ttttgaaagc ttaatctaag taaaacagtt ctgactagtt atgcttgtca
     6301 gaatttcaaa ggaagttttc cataaccatc atcattcaaa aataaaggat ttgaaaataa
     6361 gggttccttt gggaaatcta aagatgaagt taagggtgtt gtgatagacg atgatttcaa
     6421 gtttgatttt gactagattt ttttgcaatg tttaagagta aacaaggtaa gaactaagat
     6481 catgaagatt gagagtaaag aagatagagg acgaatgtat gagaacacac tatatttatt
     6541 tagaagataa aattgtagat gaaattccgg caaaaagtcg agaacaagct agaaaattat
     6601 ttattgaaaa atacaaagag atcaatggag atagtgaagt tccaaaagtg gtcgtaacag
     6661 ttagaaaaag gcaaacaaaa aagagaagta cgtttcatgt cagccctgat atatataatc
     6721 ttatagagcg acatagaagt gaagataata tttctatctc tcaatatatt gctacagtta
     6781 ttgatgaatt gatttcagga aagtatgact atgcttttga ttttgagggt gaaaaggatt
     6841 acaaaagtgt tgctgtcttt caatctgatt ttgagaagct aaaaaactat gctggcagga
     6901 gaaatgttaa ttttgcaaga ctactagaag agttctactc cgaagagttg ggagtaggaa
     6961 atgaatacaa gagagaaact tatgcgaaat tgtctcataa gttatcccaa gcgcttaaag
     7021 aagtgacaga agttaaagcg gaactagatg ctaaacttga agaagtgaaa aaatatcaaa
     7081 cagagaggaa gaacaacatg aagaatcaag tggaatttga cgaacagaaa gaatttgaaa
     7141 aagcaagaaa acgctataac aaaattatga atgaacttag ctatgaacac ttaacagttc
     7201 atgaataatt gagtgagggt acagaaaaat atacgatcgc agatatggtt aatgaagtgg
     7261 aaactctttt agcttctttc tttgaaaatg gtcacgtaaa cgatgaatgg cgaaaagaag
     7321 aacctaaaag ggttaacgct tatattgctc gattaaaaag gtttattgat aaatataagg
     7381 agaatagtga caaattttct aaagataaat aaggagagag tgtgattaca tttgccagaa
     7441 atcgaaggaa tattttcgcc aaaaataggt aaaaaacagt tagatttcag cagttttccg
     7501 agcgtaaata gagattataa tctaggtgat gaggtacaga tactaaatat tgatttcaaa
     7561 gaactagact tcgctgttgc tgtttccaac aaacccaagg cattggaacg agtgaaaaaa
     7621 atataccaag agaatgatca aaatatcaaa aatatgatca aaaagtatag acgagataat
     7681 tcaaaagttg aagacgtttt attcaacggt acggcaaaac atgatttgaa tgtttatatg
     7741 gcattaggag tggctttgta ctgtaattca attaatcaga cagatatttt ggttaatatc
     7801 gtgaggaata gctatcaaaa aatattaaaa ataagtagcg aaacaaaccc ttattatgca
     7861 atgaaatatc ttggggataa tttattaaat gataaaaaat tgatgcacaa cactgaagag
     7921 ctgttatcta atttggctgc gattaacttt ctattcaaaa caggttctga agattatttt
     7981 atagataacg tactaaaagg tgcttacgga acagcatttt atccgcttta caatatgaaa
     8041 cagcataaag ccgaacaaaa ggataacaaa cttgaaatta aaaagatgaa agaactatta
     8101 ggtataggat ttgtaaaacc caattcaaaa gtcactattg cttcgttagc aactactaac
     8161 aatgatggga aaatagtaaa tgggtttgac gattcagata tagatatatt gtcaaaatca
     8221 tatttttctt tgtatggaga ttttgcagat ttgatgggta ttgatagtta cttagtcaat
     8281 aattttgaga tcaagggtag cgagctgaat gatattgtgt atttcgtttt aatctctcta
     8341 tatgcaattg atcagaatac cgagtaccga caaattgact atttgctagt tttttatagt
     8401 ttgttatatc agttcgtttt aactcggttg tttaaaaatg ctaaggaaga attgatcctg
     8461 aattctgatt atgaaatagc aaaacaaatt gcaagtatta gaaaagaaaa caaatctgaa
     8521 gtaatcaaat taagaaaaga attaagtatt gcgagtaaag aaaacggtcg gttagaatct
     8581 ttagtcaaat cggcaaaaaa agaagaggaa cttttgaagc aagagattaa agaattaaaa
     8641 ggaatcagaa aagaacttga acagctgagg tttgaaaata aagtattaaa gcaattgcag
     8701 gagcaagaac atagacaatc attaaatggt aaaactgaag agccttcact gtctgaaatg
     8761 atagcttatc taaaacataa aaacattctt ttagtgggag gacatgtaaa ttttcaaaat
     8821 aaattaactg aactattacc aaatattaaa atgtttgatg taagcgaaaa taatggaaag
     8881 atacttaaaa atttgaatac gtgtgatgcg atttttctat atacagatta cttgaatcat
     8941 ggtctatatt atcgtgttat gagtgaaatt tctaataaag ataagatatt ttatttggat
     9001 aatcatgtga atatgaactt aacaattaaa cgtatttacg atcttttatc acttatataa
     9061 agagagaagt gataaatagg acacaaaatt tggaaagtag gtaagtcact atgagagaac
     9121 taactttatc ttctaaggaa ttagaaaaga aaactgcttt attaaacgaa atatttagtg
     9181 ctgattgtat aatccaaagt ttaaaagaaa gttcattttc aaaactaaca gatcaggaaa
     9241 aaatttctta tatgctaagt ttagataatc taggaactaa atatgatgaa tcagcaagta
     9301 gcgataagct tttgattgaa ttagtatcaa gtcttagtag ttttggaaaa atgaaaagat
     9361 ttaatgtgat attagaaatt tttgcttggt taatcccttc atttatttgg tttttttata
     9421 ttttcatagt tgaatctgag ttaatagcca aggtctctct tggactgtta attccgatat
     9481 aaataggttc agcaatttac tttaataact tgtatacacg tattcaaata aaaaagcagt
     9541 tattacatga aggattaagt ggtaatatgt taaaaagaat tgcatgggat aaagataata
     9601 aaacagatat tgagcttaaa gaatataaat acaattattt ctcgagatgt atagatagaa
     9661 agttactgtt taaaaaagaa ggattagaat ttagttttga tgaagatgaa tttgaaaaat
     9721 tagtgatgga ctggcgtaag aatttactgg atacggtaca attctaaaag caattgaggt
     9781 cgaaattccg atacttgaat catgatctat attatcgtgt tatgagtgaa atttctaata
     9841 aagataagat atttcatttg gacagtcatg tgaatatgag cttaacaatt aaacgtattt
     9901 atgatctttt atatgtttat aaacattaat gaggtgctaa aattgacaac aataactatg
     9961 acaaaaaaaa tagaagtata tgttgatgga tcacaagaag aaagggattc cttttttgat
    10021 tttttttgga aaaatagtag agaatatgta aaagcgttga atctggtata taaacagcta
    10081 atgtttgaag agttgataaa agatgcaatt aaagaaatgg atcaaggtta tgctgagaga
    10141 gaagaaagta ttcaaaatcg gattgaaaag ttagcatata ctgatccaat agatcaaaaa
    10201 aaacttgata aagcaaaagc tgaattatct aaattgagaa atgaaaaaaa taaagaagcg
    10261 agagaaatat taacgcaagc gatagggttg aagagtcaaa cgagaacacg agatgtagca
    10321 aaaaaattag actttgactt tggagatttt gttgattccg caaatatgaa agctagtaaa
    10381 gattttggca atgattttat cggaattgtg accggacaaa gaacgcctag aatatataaa
    10441 aatagaaaca aatatggatt actacctttt agaggtcgag atattaaaat ccataaagat
    10501 gataagtttt atatttattt acctaaaggc tttaggttta aagtgaattt aggtagcaag
    10561 ccaagaaaag caagagatgt tgcttcagtt ttacaacaca ttatggatgg cgattacaaa
    10621 ttaaatcaaa gtaatcttat ttttgatgga agaaaattat tttttaatct aacaatttct
    10681 tttgaaaaaa gctataatga aatggaattc aagaaaggta atgaattgat cgtaaacttt
    10741 gcagatttgt gtagcggtga atgtttaatt aatgataaat ctgtaatgtc ttttggtgat
    10801 agccaatata taagaaactt caaaagtaaa attttagcaa tgaaatcaaa agaacaaagc
    10861 cgaggagtct tttctaaggg cggtcatggt cgaaaaagaa aattagatca agatcgatgg
    10921 gaagcaataa agaaaagaga aagtaatttt gttaaaactt ataataatca atgttctgca
    10981 aaaatcgtta aaactgctat tcgcaataaa gctcaaatta ttcgtatcat tgaaccagat
    11041 aaggcttatg gcgaatgggc ttactatcaa ttgaaagaac aactagtaaa caaaggaaaa
    11101 agatatggga tagaagtcag aagttagtaa attaaacaat cgttgatttg gcaacgaaat
    11161 agtgagggaa aatccactca ctgaagggta aactccgtca agttgtgtga ccagacggaa
    11221 ggacgaatgt tgttgaggtt ttagaaccat ataaaacagc atgtttctca aatttttagg
    11281 ataagggaaa ttgctagcag tttgttttag aaccatataa aacagcatgt ttctcaaatg
    11341 agtactttaa attaattgat ggcgttcctg ctttagaacc atataaaaca acatggattt
    11401 aaaacaagaa gtaagtcagt tctcctttta ctttagtaag gaaaaataaa gtattctcaa
    11461 taaaacttaa aataagcaaa cctttgtttt aatagctaat cgaagtaaaa cccaaagcca
    11521 tatgaacccc tgaatcagcg aaagtttatg atgatttgga ttactaatag tttaggaatt
    11581 agatggtaaa tctaaattaa acaatcgttg atttggcaac gaaatagtga gggaaaatcc
    11641 actcactgaa gggtaaactc cgtcaagtta tgtgaccaga cggaaggacg aatgttgttg
    11701 aggttttaga accatataaa acagcatagt tctcaaattg tttaaaatga ttgtcaagtt
    11761 aaaaaaatct gggatcatat aaaatagtat agttctcaaa tatgattaga aaccctatta
    11821 aagagcaata ttaagccaac ttacttaaat cgtttaatta agaacaataa tggctctttg
    11881 tcaaatagga ctgatagagt gagataagaa catctaaggt agaattcctt ttctacttta
    11941 gatgtttttt gattcatagg taatcagatt atttagtaag aaaattctgg tcttcatttt
    12001 ccgaaagctt cgaaagccat aagcgactcg tttcaatgct
//
LOCUS       DBBGSP010000085        11925 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000085 DBBGSP010000000
VERSION     DBBGSP010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.085"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            594..800
                     /locus_tag="ACIZE9_002757"
     CDS             594..800
                     /locus_tag="ACIZE9_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HGC6094566.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(1002..2003)
                     /locus_tag="ACIZE9_002758"
     CDS             complement(1002..2003)
                     /locus_tag="ACIZE9_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC6094567.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(2008..3921)
                     /locus_tag="ACIZE9_002759"
     CDS             complement(2008..3921)
                     /locus_tag="ACIZE9_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC6094568.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(4089..4595)
                     /locus_tag="ACIZE9_002760"
     CDS             complement(4089..4595)
                     /locus_tag="ACIZE9_002760"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGC6094569.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4755..5195
                     /locus_tag="ACIZE9_002761"
     CDS             4755..5195
                     /locus_tag="ACIZE9_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGC6094570.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(5221..6336)
                     /locus_tag="ACIZE9_002762"
     CDS             complement(5221..6336)
                     /locus_tag="ACIZE9_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094571.1"
                     /translation="MKNYHLSCSLKKGNPIEGEEYRIRYFFHLMYWQSFDENHSDILS
                     SIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSITYVPEEMNKFVHPL
                     ITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYLEEDLLDTPDKVQES
                     WGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGTKKKVDAFGKSAEDR
                     DFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCMLVRDIFIKHEQPVIF
                     YIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYPIDKKAYDQTNTQIF
                     YWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6381..6737)
                     /locus_tag="ACIZE9_002763"
     CDS             complement(6381..6737)
                     /locus_tag="ACIZE9_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094572.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(7035..8009)
                     /gene="sgrA"
                     /locus_tag="ACIZE9_002764"
     CDS             complement(7035..8009)
                     /gene="sgrA"
                     /locus_tag="ACIZE9_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HGC6094573.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(8205..9044)
                     /locus_tag="ACIZE9_002765"
     CDS             complement(8205..9044)
                     /locus_tag="ACIZE9_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGC6094574.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            9229..10116
                     /locus_tag="ACIZE9_002766"
     CDS             9229..10116
                     /locus_tag="ACIZE9_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HGC6094575.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(10710..11404)
                     /locus_tag="ACIZE9_002767"
                     /pseudo
     CDS             complement(10710..11404)
                     /locus_tag="ACIZE9_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
     gene            complement(11388..11786)
                     /locus_tag="ACIZE9_002768"
     CDS             complement(11388..11786)
                     /locus_tag="ACIZE9_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HGC6094576.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         3552 a         2342 c         1797 g         4234 t
ORIGIN      
        1 atatttggta gtggcttttt tggttctgca agggtggtac agaacatcaa tagtcggtgg
       61 gttagaacgt atgtcatcgc atctttggag aaggttgtat tggtattatt cgagttactt
      121 gttagatgcg ataacaaagt tagtatacag tagtaaaaaa tttatctttt ctttttttta
      181 ttatttttgt ttcttatttt ctaaaaaatt aaaaaaaatt ttggtgaatt aagtatttcc
      241 ttgataacac tggcttttgg cctcatttta ggttatcatt tgtaatttta tttcacagtt
      301 gatatgattg ttatgtaaaa taaaaaagtt taggatacat cgaatttttg gggaaattct
      361 tttgggggta tcctaaatct tttctattat attcccatat tttctattat tggtctagac
      421 gtatgatggt aaactttgta cctatctgat tgctgaatca ttaattgctt atcattagcc
      481 atctttgttt caagttcgct agatgatcat tttattcaca tcctaacaaa cttgtcacat
      541 ttatagattc ttaatctatt tatcatacaa ttataaaaaa ggaggtgctg cttatgaaag
      601 ctatccatat ttctttgctt tttttcgcta gtgcattgat tttatttgct attcatcttt
      661 gttcccagcc ttatatcaat aacaacggaa tattagtgga accagcattc ttttgcttac
      721 cactcggctt tttgtccctt cttgcctccg caggcttcgg atttgttgct ttttttaaac
      781 gatcaaaaca acaaatctga cttataaaat ttacgtaaaa gagatcgtga caataatcgt
      841 gtgatattcc caaatttcga ataaaaggtg ccccttgcca tctctaactc ctcagtcaca
      901 agttacaata ttcataaacc atgaaaagct tgtttattga aattgctcct tgtgacttgg
      961 agctaagtga cagattacaa cctcttttgc atcataagac tttactcctt gaaaaacatt
     1021 actaactttt gatatgtttc ttgcgcttgt ttattgctga aatcaaactg atattcatgg
     1081 ttcaaaacag catttttctc cgcataatct acttttgtga ctttcacccc cgctttctca
     1141 aatacagaag ttacttcttc catttgtttc gtaaacgtat ttgtatttcc atccgttaag
     1201 aatgtgtttt gcgtccaacg atccgcatgt ctgaccaagg ctaaactttt gaccttctct
     1261 gattgttcaa agtccttatt atcaaagtaa gcccatccac atttttcata aagaaagcta
     1321 gagattttat cacttacttg agtaagtgca gaaggatcca acagaccaga caaagaaata
     1381 aacttcgtaa tctgcttgtt ctccaaagtc ggatcaagat gatcagcttt tttaatttct
     1441 tcattttgaa gtgctaacaa atattctcca ctaatttgtg cacctgccga atttccacca
     1501 atcgaaatat tcgaccaatc tgcttgatct tttatctctt ttttagctgc ttgaatggct
     1561 tcgttcaatt ggataactgg tgtaggatgt tttgcttccg gtgatcgttc ataatctata
     1621 tttacgatga tttgctgcgt gtctgaacat agatattcca aataatcacg acaatcattt
     1681 ttatcccctc ctacatatgc gcctccatgc atccagaaaa gaatcggtaa ttttttcttt
     1741 tccactttcg gtgtgtagat atccatatta ttatttttgt actttgaagg ataggatatt
     1801 tcttttttta tatcgatttg ttcgattttt tgctggaaat catctggtcg ggcatatact
     1861 tgttcttttt cacttgtgtc aaattgtttt ctaacaagca agctaatcgg ctttggtgtg
     1921 atttgattaa tcaaaaatac agtgactaaa ataactacga tgataactgg tactgcaatc
     1981 actattcgct tgaaccattt cattcattta ccctctcttt cttcgccaaa tccatgtgat
     2041 aatcgtgcta acagataaaa atccacctga ataaatgaga agcgaatgtt tcttttctcc
     2101 agttttcggc aacattcttt tttttgcatc tgtctttttt tgtactttca ctgtcatctg
     2161 aatcggttgc gtatcatcac ttgattgatc ctctcgaggt tcattctttc ccttattgtc
     2221 tgcattctct gtcggatctt gcttttttgg tggagctact gggatttttt tgtaatagaa
     2281 aataatagtt ggtatcgtct cattaaaaat cccttcagtc ggtccttcaa catttgctaa
     2341 ttcgtatcct tcgaatgtct tttgctctgt catataattt tctccataag ctccgtaaag
     2401 ctggatttcg tcctggtctt tgagtagact tttattgttt tcatccacat actttacgtt
     2461 tatctgatca tggaacacta ctttcaaaaa gtccgttaca tgtttcgtgt aggcagcatg
     2521 gtcaacttcc tgtgcctttc catgccctgc tccttctact aataaaagat ctttataccc
     2581 tcctgataac tcatataatt tttgcgcgtt agacacaggt actacatcat ctgctgttcc
     2641 atggataatc aatttaggca atgaatctga cattccaatc gtaggtagag cagcttttgt
     2701 atccaaatgc atctcctgat caaaatagta ttgtttcaaa aggcccataa ataaatcttc
     2761 atgctcttga tccccaatga tgtctaactg attttttatg gcatccggta gtgcgggggc
     2821 tactgtctgg ctgtacgtaa aacgtagttg ttcatcaatt gatgcaaatc cgcaattttc
     2881 aataattcct ttgacattga caggaatatc tttcgctaat acagacatca tcgtagctgc
     2941 tcccatcgaa ccaccataaa gtaaaatctt ttgagatggc cgctctcgaa cttcttgatt
     3001 tatccagtaa aggacgtcat ctgactcata ttgtccatag gtcacataat cgcctccgct
     3061 attaccagtc gctctggaat caacaaataa taaattatac ccggccttat aaaaatcatt
     3121 gtattcttct gtaacgatcc cgttattcca attccctcga aatccgccat ggatcatgac
     3181 tgttttatct gaaccttgat cgacataata tgcatataca tccatcattt tgccatcttg
     3241 tttgtttagt acagtttgat gaagttgttt tgtatttgga tagaagcctg tgttttctgt
     3301 aggcgttgtc ccatcatctg tacctccaag catcgacatc aacacactgt tttttgcaaa
     3361 agcgatatcg tacaatagat aagtagcaat cagatgtttg ataatctctt tatctacacc
     3421 ataatcatta acagcaagct cagtgactaa taactctatt aattttgact tgatgtcttc
     3481 tgttggtcca ttaagtattt ctgtcatctg tttaccgaag taattcaaat attctttacc
     3541 attgaaattt tcacctttac cgatatcatc attttctgtc ccattctctt tgtcacttac
     3601 tttagcagaa gaggattcgt cgtttgacat ttttgtagct gttgcttctt ctgtttgttg
     3661 gttatctgtg gtagcggtcg tttcttgatc tgtgctagta acagatgtct caaccgttgt
     3721 ttcagtattt gtttctgttt gtgaagtact cgatttcgtt tcatttccag catcagtagt
     3781 ttctgtggtt tctacctccc gagattccga ttcggaagaa atgctctctc catatactgt
     3841 ccattgcggg acgcttgtac ttacagcaaa taagatgacc aacgctccct ttaatacttg
     3901 ttttgttctc aagctattca ctccttttta tgtttctagg agaattatat gtaaacgcaa
     3961 acatttttta tacaaaaaat aaatggttta tcccataaaa atagaacagg attattttct
     4021 cattttacgt aataaagcag aatggataaa ccagtatcca ttctgctttt tttaaacgaa
     4081 gaaacaactt attgctccaa aaatgtcaga aatcgtttat cccaaatttt ctcgtaaaaa
     4141 gcgattgttt cctttgcttt cataaaagga ttatcataag ttgtcgttgc tcctctacac
     4201 atcataagct ggtatcctaa tccatgagca aacttcacag tcgtatctat acaatactct
     4261 gcttgtgccc cacataattc gatcgaatga cagtccaatt cagttaataa aacactcaaa
     4321 ttagtcttat aaaatgaatt cgcatgggtt tttctcacaa aataactgtg ctcaggaata
     4381 gataattccg acaatagctc ccatggtttt gtttgtggca ctaattgagc atcttcgtgt
     4441 tgaacgaaaa taactggttt cccaatcgtt tcgtatgttt tgattctttt attcactaat
     4501 gctgtcactg tttctaattc gtgtatcggc gaagaatcaa aacatacccc tttttgtaaa
     4561 tcgatcacta ctattgcgtc ggctgtgttt gacatacttg tgccttcttt cttttttctt
     4621 gatttaatag tatttcttat ctagctagtt ccattatacg tgacaacatt ttcttatttt
     4681 acacctctaa atggcacttt tcgactattt cttcatgtta ttatttcata aatacttagc
     4741 tattggagga atgtatgatg attaaattgt atacaggttc tggctgctcg tcttcaagac
     4801 gcgcaaaacg ttggcttatc gtccatgata taccgtttat cgaacagaac ttaattcgtc
     4861 aaccactaac caaaaatgaa tttatccact tactaaaatt gacaaacaac ggcgtgaccg
     4921 aaatgctctc tactcattct attagttata aaaatcttgt tcacagaata gatgaactca
     4981 gtttgagtga actatatatt gagattcgta catccccttc tttattgaaa aaaccgatta
     5041 tctacgacca atctgcaaaa cttttgactg gatttagcga agataaaatc aggatgttcc
     5101 tttctaaaac taaaagaaag caagagctca acgaactctt gctttctggt catcttgtcg
     5161 attttaaaga aaataatctt tttgcaatgt cttaattttg gcataaacaa tctgcttttc
     5221 ttaattaacg aaatccaatt tttccaatat ggatctattt ttctcattcc tgatttttat
     5281 gatttcagct ttcagacgcg cccaatcatt ttttgtaggt tgtccattcc agtaaaatat
     5341 ctgtgtattc gtttgatcat atgccttttt gtcgatagga taatcgctaa tgacaatatc
     5401 aggtaactga tcagcggatg cactatattt tattgggcgt tcagtcatag ataatatcct
     5461 tttctttgcc cataattcct gtgttttacc atactttgat tgaatataga atatgacagg
     5521 ttgttcgtgt tttataaaaa tatccctgac taacatacag tattgaaaaa tcaaccgtct
     5581 gttcttttca taataagtat taagctctgg aattctgcga gctaccccac taaaaaactg
     5641 ttgcatgatt ggatacatca ctggaaatat atgctgaaaa tctctgtctt ctgctgattt
     5701 tccaaaagca tccaccttct tttttgtccc aaaaaccctt gaatacaaat ggatcattgc
     5761 caaattgaca tatagataat ttttttctga agttgtaaaa caaatcttga agtttttttc
     5821 aaaattttct acaatagacg attcaatcca gccccaactt tcttgtactt tatctggagt
     5881 atccaacaaa tcttcttcca aataggtgtt cattacacca aacataaaat aaaggtaagc
     5941 ttgctctgtt ggagtgatgt gattcatcga ccagaagttt gcttcaaaaa aaggctctag
     6001 tatgtaatgc gtaaactctt cttttgttat caatggatgc acaaatttgt tcatctcttc
     6061 tgggacatac gtaatcgagt ggccttgttt cattcgttgc aacgaaattc ttagtaggct
     6121 gatccatttc tttctatcta tactacgcgt atatggcgca tgtttcgcaa atttttctaa
     6181 tagttgacgt ttatttttta tacttgataa tatatcagaa tgattttcgt cgaatgactg
     6241 ccaatacatc aagtgaaaaa agtatcggat acggtattct tctccttcta tcggattacc
     6301 ttttttcaag ctgcaagata aatgatagtt tttcaaaata gtattaagtt ctcttaattt
     6361 tctttgaatc gtacgcaaac ttatataatt ttttgactaa gattttctaa ggattgataa
     6421 gtacctttgt aaagtgaatc cagtaaaata taaccaatcg ttccctctaa aagtatagaa
     6481 taaactttac tcagtaaaaa ctgagaagaa aactcgactt ttatcatctt gttttctgaa
     6541 agaaaagata atttatattc tggatacctt tcgcaaaacg attctgcttg ttgaatcacc
     6601 gaattcatct tagccagggt gtagtttaga tctaaagcga tatccttcac cacatataat
     6661 ttctcgtctc tttcataaca atagttcaaa aattgatata cttgcctttc attgatatca
     6721 ataaattctt caaacaaagt acatactcct ttttatctat tatttagact tattccgaca
     6781 gctacatgaa taacgtacaa atagattcgt tactgatttt tcagagatac taccatgcgc
     6841 agtgtgcatt gtcaattatt cttgctctta ttttccattt gtgttcctgt tatttcctgt
     6901 ttctcaaata tgttagtaaa caaaaataga tctggcaaag ctacaacttc gccaggcaat
     6961 acagcactct cgaatgaaat attcactcaa aaatctatcg ttttattcaa ttttagatct
     7021 gttgctttta ttctttattt cactcgatgg aagagagaac gaaaatagct tgctcctaca
     7081 atcaaaatga gtaacacacc catccatgta attagcttgt tcaaggttct actaccagtt
     7141 tctggtaaat cgctttttct attatctgtt tctttcgctt tttcttgatg atcaattcca
     7201 cgagaaacaa aatcaggctg ttttagcaca ctttttaggt tgctccctgc atttctcttt
     7261 tgttccttag ttggtatgat aggtaccaaa tcaagttcat tatttacttt tcctgtgctg
     7321 ctttcgctgc tcgtgcttcc tgtgctactc tcactactca tgcttcctgt gctactttca
     7381 ctactcgtac tctccgtact gctttcgctg ctcgtgcttc ctgtgctact ttcactactc
     7441 gtactctccg tactgctttc gctgctcgtg ttttctgtgc taatttcact gctcgtactc
     7501 tctgtactgc tttcaccgct cgtgttttct gtactgcttt cactacttgt gctatccgta
     7561 ctgcttggcg gtccaacaac tgtccaactg cttggtttca aattctccgt gatcgtcatc
     7621 tgtccatcat aaaaaacaat caaatcaact ttatctttac tcttgatctc atcaatcgat
     7681 agttctgcag aaatcattat tgtatactca ataccagcgg tccattgtac gtcttttaaa
     7741 taaacttccc caataacttt ttctgaactt ccattaccat cccaaccata tgttagaaca
     7801 gcatgtacat cactagcatt cacgcttttg tttggtttga ctggaatagt aatgacttgt
     7861 tgtgtcatgt cataaacaat ccgatcagtt ttcacagtaa atgaaagatt ctcatttgcc
     7921 cgttcatttg cagaagtact gattccaatc attgctgcaa ttatactcag cccaagaata
     7981 acaaataata cggtcgctgt tttcttcatt tctatcactc tccatataat taccttctat
     8041 ttgataaagg aattatataa aatgaaaatg atgagaacac gacagtcagt tgtgaaaatc
     8101 taacaaaaga tgtcgtgtat tcgcttgaat ttgtttactt tttcgtttaa tcaatgacag
     8161 acttaaaaaa gcaagaccga tatcagcctt gctttcttca tcttttattg ataaacagca
     8221 gtgtatttct tcatccgctt tgttttatat gcatagagta acaaaccaac aatcaagact
     8281 aacaagaata atgtagttga tatagatgct tcagccccaa agtttccccc agtaattatt
     8341 gtattttgcg attggatcag agtggagaaa aaaccttgtt cttgcgttcc gctgactggt
     8401 atacccaaaa tagctccttg tgtccaattc caagtaatat gagcaccaat agccgtaaat
     8461 aaacttcctg tactgtagat aagtgcgctg aaaaagcaac ctgctaaaaa gatattgaaa
     8521 actgccagaa atgtcatgtt aggattcaat ccgtgcaaaa gagcaaataa tgcagcagat
     8581 ccaatcattg ctattaacgg accaaatcta agcatctgat gctgaaaaaa gccacggaat
     8641 aaaagctctt ctgatgcccc cactgcaata aataaaataa aactcgttat cagcggcaca
     8701 atgtttgcgt ttcctgaatc taaccgatac gcccccgtca aatataatgg actagtaata
     8761 agcagaaaca ctccaattcc aacaacgaga cctcccgcta aataccccca gtcttttcct
     8821 cgaacagaaa caccataatc ttctattctt tttccttcga ccttactagc aagaaataaa
     8881 gctagtaaaa aaacagctaa atgtccgacc gtaccggcaa ttgctccaat ccattcacta
     8941 tttccaataa acatatccgc aagtgcatta ttgacaagaa ttcctaaaac aaaaccaaca
     9001 aagactatta aaacagatcc aatcaaccga ataatcctga tcatctttca tccctccttt
     9061 atattaagtt taacaaccct tttctttctt gtctcgtgaa aactatgtaa atgttctcca
     9121 tcatagagag aatagatttt tacgaactaa gaatatctac agcaacctta cgaaaatgaa
     9181 agactgtctc cctaattctt ctgttagact gtttttaata aggaaaggat gggaaatttt
     9241 ttgaaaaaac aactactaat tatgtgcctt tcagcatgtg caattttact attctcaggt
     9301 tgtagcaagt ccaatgaaac gattgcaacg tttaaaggtg gaacacttac agttcaggat
     9361 ttttatgata acccaaaagt taaatcaaat aatcaaacac tattaaaaaa aatgattgtc
     9421 ttcaaagcat ttgatgatgt atacggaaaa gagatttctt caaaggaagt aacaaaagaa
     9481 tataatgaac aaatcaaaaa actcggtcca aactacaagg aacaattaaa agcagttggc
     9541 caaacagaag agacatataa gaaactcttt aaacagatgc tggctttcca atacggtttg
     9601 aaagccaatg taaaattaac agataaagat ctagacactg cttggaaaga attctatcca
     9661 gaagttagta cacagatcat tctattttcg actaaagaag aagcagataa agcaaaaaaa
     9721 gaagcaaatg aaggagaaaa tttctccaag cttgttcaag cttatggaaa aaataaaaca
     9781 ttaaaggaaa ctgatggaaa aatgaatttt gattcaacca atccagagat tcctactgaa
     9841 gtaaaaaaag cagcatttaa actaaaaaac ggggaagttt ctgatatcat tcctgtaaca
     9901 gatccaacga cttatcagca aagctattat ctagtaaaaa tggtaaaaaa acaggataaa
     9961 ggttctaata aagacaaata caaatctgag ctagaaaaaa ttgctaccga agcaaaaact
    10021 cttgatacgg aattcatgga taaaacaatc cgtaaagtga tgaaaaaaga caatgtaact
    10081 attaaagatc cttatgtaaa aaatatattc aaataaacaa atttgaccca attggggatg
    10141 tggcaaaatt tgagaagtga tttttggaaa ttccttctta tttttgaggc aaaccacttt
    10201 tgccacaact tcatcggggc ctttttttat ttgtaccaaa acaaatcact ggatttgtta
    10261 caatcatgag gatataattt aaaaaagttt tttatttcta tcacatgaat caatgcgcca
    10321 ttaagtagat tctttcatgc ttccctattt tttcacttgc cgtatcgctt caaaaacaac
    10381 tatcataaac tcaaactcga ctgaaaagtt attttaaaaa agactaaaaa tatcccttct
    10441 ggacttgttc ttcttattct gttatactag agaaacacga aagatatttt tatgcgacac
    10501 ttttcatttg tttttatgaa atttattcaa aactggcgta acttcagagt tacaaggatg
    10561 tattagaggt tagggaatac atcgtttaaa tgagaaataa gtaatagtta gtaatagtca
    10621 cccaaacttt aaattaatga atattgaatc gtcagatagc ctcctcgagt tttcgagaag
    10681 gctatcgttt attttatgga gaaattgatt cagaagtaat cagcgacctt ttttagttca
    10741 ccaatcgttt ctgcttggaa agtttgcacc caatcttctt ggaagcccct cactgcttta
    10801 tcaatcgagg gcatctctaa tacttgatct agtagctctt tacctaacgt tatcgctgag
    10861 ctccagatcg aatggctgta gtgacttgtt cacaattttt gaaactagct gctaatattt
    10921 ttgttggtct ttgcgtacgt tcgatctcag tccgcaacga atcaatcact ttcatagcat
    10981 caatgccttg attttgcatc ctgttataat aaggtgcaat ataatctgct ccattattaa
    11041 tagctaaata cccttgtaat tctgtgtaaa tagctgtacc ggtaatcaaa taaccttctt
    11101 ttttcaactt tttgatcgct tgaaggcctg cttgattcac cggcaccttg ataaacgtat
    11161 cttttcccag ttcttctatg ataactcgag catcctctat catttcttct tccgttcttc
    11221 ctattgtctg aatatggata ggaatctgtc cgattatttt tttgatttct ttcatatgcg
    11281 agaagaagtt tgacgctcct tcttttttca gaattgtagg atttgttgtt acgcctgtta
    11341 aattcaaaaa ctgttgacaa gaataaatac tttttgtatt tgctgtatca agcatgattt
    11401 ccatatagct ttcccccatt ctgatcctct tgatcgattt taatgattgt cccctttctt
    11461 aaatgcggca tttccttatc ttctacatac attgttcctg gaagttccgg ctcatgagat
    11521 ccatcaaatt ttatcgtgat atgtcctaat tcattcaaat tagtttggac aacatctcct
    11581 actgctgtga ttacatacat ttgtttatca aaacagagct tcatatcaca agttatttct
    11641 tttcttacct gattcaattc aatcttataa caataatctg ttaatgtttc cggtgcttca
    11701 tctccaaata aaatcattat tttttctttc ctgaatactt ctgcttctat accaacatct
    11761 gttacaaccg tttcaaagat cgtcatctct gttcctcctc gtaaaatatc atttgtctaa
    11821 tagtttttat tcaaaatgtt tctagattat aaaatttatt gaataacaca ttcctaacgg
    11881 aatttgtttc gatattgtgt gatttctcag agtacaatgg atgta
//
LOCUS       DBBGSP010000086        11780 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000086 DBBGSP010000000
VERSION     DBBGSP010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11780
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.086"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            506..1069
                     /locus_tag="ACIZE9_002769"
     CDS             506..1069
                     /locus_tag="ACIZE9_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094577.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1130..1495)
                     /locus_tag="ACIZE9_002770"
     CDS             complement(1130..1495)
                     /locus_tag="ACIZE9_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HGC6094578.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1571..1816)
                     /locus_tag="ACIZE9_002771"
     CDS             complement(1571..1816)
                     /locus_tag="ACIZE9_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6094579.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1886..2140)
                     /locus_tag="ACIZE9_002772"
     CDS             complement(1886..2140)
                     /locus_tag="ACIZE9_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094580.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(2304..2627)
                     /locus_tag="ACIZE9_002773"
     CDS             complement(2304..2627)
                     /locus_tag="ACIZE9_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094581.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2814..2887
                     /locus_tag="ACIZE9_002774"
     tRNA            2814..2887
                     /locus_tag="ACIZE9_002774"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2848..2850,aa:Ile,seq:cat)
     gene            complement(3272..3769)
                     /locus_tag="ACIZE9_002775"
     CDS             complement(3272..3769)
                     /locus_tag="ACIZE9_002775"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HGC6094582.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3809..4618)
                     /locus_tag="ACIZE9_002776"
     CDS             complement(3809..4618)
                     /locus_tag="ACIZE9_002776"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6094583.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4952..5809
                     /locus_tag="ACIZE9_002777"
     CDS             4952..5809
                     /locus_tag="ACIZE9_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HGC6094584.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5802..6704
                     /locus_tag="ACIZE9_002778"
     CDS             5802..6704
                     /locus_tag="ACIZE9_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HGC6094585.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6737..7087
                     /locus_tag="ACIZE9_002779"
     CDS             6737..7087
                     /locus_tag="ACIZE9_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HGC6094586.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7136..8059
                     /locus_tag="ACIZE9_002780"
     CDS             7136..8059
                     /locus_tag="ACIZE9_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGC6094587.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8137..9030
                     /locus_tag="ACIZE9_002781"
     CDS             8137..9030
                     /locus_tag="ACIZE9_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC6094588.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9068..9631
                     /gene="amaP"
                     /locus_tag="ACIZE9_002782"
     CDS             9068..9631
                     /gene="amaP"
                     /locus_tag="ACIZE9_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGC6094589.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9645..9833
                     /locus_tag="ACIZE9_002783"
     CDS             9645..9833
                     /locus_tag="ACIZE9_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGC6094590.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9846..10748
                     /locus_tag="ACIZE9_002784"
     CDS             9846..10748
                     /locus_tag="ACIZE9_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGC6094591.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPYPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10780..11022
                     /locus_tag="ACIZE9_002785"
     CDS             10780..11022
                     /locus_tag="ACIZE9_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGC6094592.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(11278..11649)
                     /locus_tag="ACIZE9_002786"
     CDS             complement(11278..11649)
                     /locus_tag="ACIZE9_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094593.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4175 a         1985 c         2232 g         3388 t
ORIGIN      
        1 attggtcgtt gaatgggctg aatagtagtg tataaaacaa ttttgtggag cgtgaagctt
       61 ttatggtaga ggaaaatacg aataaagtga tgttgataaa aagattccta tcttgaatat
      121 gaatcgagat gtcttgaaaa tgaatgagtt tgaccaatca ttatcctatc gaaatttaca
      181 gtttcgttcg attggtctgt caattaatga aaaagtaaaa aagaatatgt tctaggaaga
      241 gggcggcaca tctaaatttt taagtaacgg acagttcaaa tatcaagcat tgaaagaggc
      301 tatcctactg tttgaaggaa tacgaatata taaaaacgac aaagaggaaa aagtagttca
      361 ttaaatccct tcaagtgatg aaagaatgag atctaataaa acctgatctt tcatctgttt
      421 ttttaataac gtaataattt ttttattttt tgtgctttcg ccgttattgt agagtgattt
      481 agcattctta tttttaaaaa taactgtgtt atatattaaa aaaggcataa tagttataag
      541 cttttttaaa gaatatttag aaattattaa ttttcgtctg aaaacaaaaa aagaaagcgt
      601 tattatttta gtctattttc agggggggaa ccttatgata aaaaaactat ttttactatc
      661 aatattaacg ctagcaatgg caggttgttc tgactctggc ttagcaactg aactgatcac
      721 aaaatcaact gaagccacga cagaggagtt aaaatgtgga aacgatcaca gtgactacag
      781 aggcttaaat cgacgatgca tgggaatatt aggcagaagc aattgtaagc atcgatgtag
      841 taatcgaaga aggtgtagaa gaagcaacag aaaaatcaaa agaaagatca aaagaagcaa
      901 tctgtgctgt gcatcgtata cagacgtcga agatgcggta cttttaaacc acgtcaggag
      961 atgttcattt atgtctaggg aagttggcga tgaaccaaaa ctagagtacg cttttagttt
     1021 tgcacgtgag gatgaagata accctaaaac ttacgacatt ttagcttgat ctaagatggt
     1081 taaagctttt taatgaagta agaggagata gaaggctttt ctagttatat taggtaagat
     1141 aaattccttt ttgctccaaa tttgctaaac attctgctag ataaacttca tcgtgttccg
     1201 gataaatcgg cacgttgcgc tctacagtag gtaaatcaaa aaatgcttcg catgatttgc
     1261 cacgatacat aggatttttc cactctggtg ctgggctgta accacgtttt tccatttcat
     1321 ccatgacaag ctgatgatat tggaataatc tataaggaga atagtgaaaa acataatcca
     1381 cagtagcatg tttctttccc cagccatttc ctcttaatgc acagcattcc cgatgttgtc
     1441 ctaaaagctg ttgacgagga agctttgaaa tcaatttttc atgccataat cgcatagaaa
     1501 tgtctccttt atatatagat tgttaacctt agacgttaaa tgaaaaaacc agcaccaagg
     1561 ctggaaaaaa tcacttcagt ttgcttgctg tttctgagcg accaattagg taatcaacgg
     1621 aaatatcgta aaagtcagcg atatagatta attcaatgat gcttggaatt tcttctcctt
     1681 cttcgtactt acgatatttg aataaaggaa tacttaacgc gctagaaaca gctacttgag
     1741 ataaagatcg gccagttctt aagaaattca gacgacaacg taaagtatcc agtaaaatag
     1801 cttcttcgat actcatttaa tcacctttca ttatagtaga atagttataa tgactataga
     1861 aagctacaca tgcaatcaat agtactcaat gttttttatt taaacgtatc aaataaagaa
     1921 tgacgatcaa taaagacaaa accagtcctg ataattcttc tataaaaaca ctatcgggtt
     1981 caaagtagtt gtaattaaaa actttccaca taaagtagat agccggaaga gtcaaaatag
     2041 ctaaataaaa ccgttctttg ttccaattca taagataaac aatacttgcg accagtgcga
     2101 ccgcaggcac ccaaaacaaa actctcacca acgtaatcat gtaacggact cctcaacgat
     2161 tcatataata aaagataaca tgttattgca tacatcacaa atgaaatgct aggaaaataa
     2221 aagaagaata gatcaatgaa aaatgaaaaa gcagaacagt tttctgctga taagcaggaa
     2281 ctgttccgct gaatgtgtct tatctatcga gaaaaaatca atggattgat atctaagtaa
     2341 ttcaatacat ataaaaagag gacgatcgca ttcactaaaa aggaaagaat gatgatccca
     2401 tagcgaatgg aaacatattt aacaaatact tttgtttgaa tacgggcata tctttttcct
     2461 ttatagctga gcatcatgac aagaagcaaa agggtaatca caccttgaaa aatcattcca
     2521 ataaacagaa ttcctgaggt ttgataattt aattggagaa aataagctgc tgccgcaact
     2581 aaatcgaata aaatcgcaat aaatggcaaa ataatcactc ctaacattga gaataaataa
     2641 aagaataaca ttttttctaa aataagcaaa taaaaattaa agtaacaaaa tagttatgac
     2701 acaagtaaaa gaaataagaa taacaatatt attttactta tattttgaaa cttgtgagag
     2761 tttgtcattc gtgctatagt tgaaaagtaa caaaaataaa ttttatttat gatgtacctt
     2821 tagctcagtt ggttagagca gacggctcat aaccgtccgg tcgtaggttc gagtcctaca
     2881 aggtacataa gaggttgtga aaaagctgcc ctgcatcaag taataagaac agccaagtaa
     2941 aaacagcttc ttatgttttt acttggctgt tcttattact gcagatgcaa gcttttgaat
     3001 accgtttaag gaagaggttg tgaaatcagc gttttgacct gagtattagc ttaacaaacg
     3061 gaaaaatagt tcctcatatt ttgccgtttg ttaagctaat accgagggtc agctgattga
     3121 acaccattta agaaagaggt cgtgagcctg ccgtttcact ctgtgtcata aaaaagccaa
     3181 tctactttga tagaaaaagc acgtaggact aaaacagttc tgcgtgcttt ttttattgtg
     3241 tgttaaatat cgtaaatgaa gatagatatt tttatgattc gacgatagag acgttgaaat
     3301 ctttcaacag ctctaaagcg gattctccgt gttttctact ggagactaac attggatcaa
     3361 caaaaaagtc tgcttcagga aaagcactct gcaggcctat cagattagag agtacacaca
     3421 agtttgtttc aatcccgact acttcgatct ctttttgttc ttctttgctt tcaaataaag
     3481 tttcctggat ttcagctaaa gtttcaggtg gaatcgtaaa gtaatacttt ttaatcactc
     3541 gttcattttc ttgtggagaa agaagaggga tcaattgcaa atcttctcgt tcttcttctt
     3601 tgtccttcag ttcaactggt atatcccgtg tgaagagaat atattcatta ttttggcgtg
     3661 ctttagctaa tctttgagca atacgttctg ccaattgatc tgactctgga atataaaatt
     3721 cgctgtttgg atcaagaata tgattttgca tatcaataat aactaacatt ttctttcctc
     3781 ctacattcat atcgtcattt tattcttttt aatagaagtt ttttaaaata taagcaacac
     3841 cagcttcttc attcgtcagt gttacttggt ttgcaatttc ttttacttgt cgctgtgcat
     3901 tccccatcgc aatactcaac ccgctgtaat tcaacatagc aatgtcgttt tcttgatcgc
     3961 caaaagccat gatgtcactc gattcgattc caaggtaatc cgccagaaaa acaagtgaat
     4021 gagctttagt gatacctgta ggcgtgattt ctaagaaatg cggatcagag aatactgatt
     4081 ggataccatc tgcttgcaga tctctttgta gcttctgtag tttttcttca ctcttatctg
     4141 ttaatgctaa tttaagatag ctaagagaag gatcttccaa catatttaaa atttgatcaa
     4201 aagaatggtt ctgtaaattg aaatgttcat aataagggtc atctttgact agatttgatt
     4261 catcgaatgt cagctgatca tcttgggttt ctcggctagc aatgatggat attttcgctt
     4321 cttgagcata gaagaaggct tttctcagtg tatcgctatc tatttttgaa cgtctgagaa
     4381 ctttcgccat ttttccatcc ttcatttcag caatcagtga accattggaa gaaatcaaat
     4441 agccaccgat tcctaattcg gaaaaaatat ctttagcaga aatgctgttc cttccggtag
     4501 cgacggttac gattccgcca ttttcatcaa atttccgaag tgcttggata ttttcttctg
     4561 gtatctttcc atttcgatca agcaaggtac cgtctaaatc aatcgctgct agtttcattt
     4621 tatcttccta ctttcttttt acatatctat tttcctgtta ccttaagatt aaatgagaat
     4681 ttaaaaaaat gaaactaact tgctttgtca ttatgaattt tttcaaaaaa cattcttaag
     4741 aaaaaggtgg ctatatatag tagtttttgg tcaatacctt tgaataaaaa gccatgaaaa
     4801 acgaatagtt agcgcttacc gatgcgtttt gtgataaaaa aattttaaaa tattcaatga
     4861 aaacaaagca tatattttgc tttaaaacca aatgaggaat attctagatg tagaacaggt
     4921 tagaaaaaga ttagaaaaag gagtgatttt gatggagaag agatacggcg tagttcctgt
     4981 ggtaactgct tcagacgaaa attatgctcc ttacttgagc gtgatgatcg caactgcatt
     5041 agaaaattgc aataaaacaa gacgcataaa attttatgtg attgacgatg gtctatcaga
     5101 atatagtaaa gaaggattgg aagaaacggt aaataaatat tcaagtaatg caagtatcca
     5161 attcctgaca gtggaaaaag atatctacga agacttccta gtcagtgacc atatcacaac
     5221 taccgcttac ttaagaattt ctttaccaaa cttattagct aaagaggatt ataagaaagt
     5281 cctttactta gattcagatg tgttagtact agacgatatc gtaaaactat atgatgagcc
     5341 gttaaatgga aaaacaatcg gcgctattat cgatccaggc caagtgaaag ctttggaaag
     5401 attaggaatc gattccgatg acttgtactt caattcagga gtgatggtga ttgacattga
     5461 tcaatggaat aaaaaagaaa ttacagaaaa aactatccat tacctcagtg aaaatggcga
     5521 tcgaatcatc tatcacgacc aagatgcttt gaatgctgta ctttatgaag attgggaaca
     5581 acttcatcca aaatggaaca tgcagacttc gctgattttt gaacgtcatc cagcaccaaa
     5641 tgaaaaatat gaacgtcagt ataaagaagg aaatgaaaaa ccttcgatcg ttcactttac
     5701 aggacatgat aaaccttgga atacgttgaa agatcatccg tataccaatt tatacttaaa
     5761 aaaattagca cacagtactc taacgaaagt aggcgagatc aatgaataaa aaagaaatag
     5821 cagtagtcgc aagttgtaac acaaaattcg taccacattt agctgcatta tttgtctcag
     5881 tattagataa ttgcaacccg tctaaatttg ttcggttcta tgtgattgac gatgatatcg
     5941 attttgaaag taaacagctt ttacgcttct cagtgaaaaa cgcacgaatg aactcagatg
     6001 tggaattctt gaaaatcaat aaagaattct ttacaaatgt ggtaatcagc gatcgtattc
     6061 cagaaacagc ttattatcgt attgcgattc cggaattgtt ccgcggcaca gaagttgaac
     6121 gtatcttata tatggattgc gacatgatcg ctttacaaga tatctctaaa ttatggcgtc
     6181 ttgacttcgg tgattcaatc gtagcagctg ttgaagacgc tgggttccat caacgactgg
     6241 aaaaaatgaa aatttcagct aaatcaatgc gttatttcaa ctcaggtttg atgctgatca
     6301 atgtgaaaaa atggttagat gaaaatatta cgcaaaaagt attagatttc atcgaacata
     6361 atccagaaaa attacgattc catgaccaag atgcattaaa tgctatctta catgaccgtt
     6421 ggttaccact tcatccgcgt tggaatgcac aaggctatat catggcaaaa gcaaaaaaac
     6481 atccaacagc agcaggtgaa cgtgaatacg aagaaactcg caacaatcct tacattatcc
     6541 atttttcagg acatgtgaaa ccgtggagca aggattttga agggccaacg aagaaatatt
     6601 acgaaaaata tgcagggatg acggctttcc gttgtgtagc taaattccct aaatatccaa
     6661 aatatgcaaa agttcaacca aaaacagatg tagttgttaa ataatagaag accacaactg
     6721 aagaggggga gtaggaatgg aaattacaat gtctaaaaat gcagtagaga cgttaattga
     6781 aaaggttggg gaaaatacaa aaatcgcact cgcgcttatc aatgattccg atccatttct
     6841 aagggacaaa ggtgcttttg caaaaggcag cttttttcaa atcattcctt ttgtttcgga
     6901 atttggagaa tatgcgacta aaatcgagca tccattattg gacatctata catctaaatt
     6961 agagcaaaat tatttcggta aacgattgaa catggacttc aacaaacagc ttgacagctt
     7021 ttcattagaa aatgaaatcg cagtactcga ttataatatc aaattaaaga actgcttctt
     7081 cagctaatag tttcgagaaa gtccaaaaag gaggtataca ttgagatact actttgtgga
     7141 tgaagaaaag aatgtaatag aaacagatga aaaaaaatat aattggctcg tacttgatag
     7201 tgcaaagccc gaagagattg agcaagcaat cgaagaattc gagcttcctg atgatatttt
     7261 cgtaggaacc gaatatccgg aagaagtttc tcggatggag cgcctttatg agacgaaact
     7321 agagcatcca ttttctttgg tagtgattaa tctagatcag tcagataatc gtatcgaaaa
     7381 aaaattaacg ccaatatctt ttgtactttc cgataatctc ttgattactt gtatcgatag
     7441 aaaaaccgaa tttgtggatc ggctgctgac aaagcatgga aatcatttaa actcgtttga
     7501 aaagatcatc acgtatacat tattagatat ttacacccat tacgtgaaag aactaagaga
     7561 gatgaaaaag cgaattgacg ctttggataa agcagctcgt aaaacaacgg aaaatgaaga
     7621 actgtataaa caggcagatc ttgaaagaga catcgtatat atcgatcata ccttaagaga
     7681 tcaacgggaa acaatggatc aattatggaa ttctgaaact ttcatcaaac gtttagacga
     7741 tgaacagcta ctctatgatg tccatttgag acagcgacaa acagaaaaaa tgatcgagat
     7801 ctatcgagat ttattagaga gtattggtga tctattcaac gggatgatgg acaataatct
     7861 aaatcatatc atgaaatatc tagattcagc tgcattaatc atttccgttc cggcgttgtt
     7921 cgcagggatt tggggaatga atacaggagg attaccgggt aaaagttctg ctctaggctt
     7981 tatactcgta gtctttggct ctttgatagc agcagtagtt ttaggttacc atttataccg
     8041 gaaagattat acaaattaaa gaatctattt aaaacaggta tcaaacaaag aaatttgttt
     8101 tggcaataca atttaaaaac taggaggaat acagcaatga cagaaccaaa attaatcgac
     8161 ccgcgaaact tgtaccatac ggagaaattt cctaaacaag atcaggatac accagcttta
     8221 cagcagaata tgattcctgt tcctgattgt ggagaagaat cctatgaagg caataatcaa
     8281 ctagaaaacc gccgtgtact aatcactggt ggagattcag ggatcggtcg tgcagcagcg
     8341 attgcatttg ctagagaagg ggcagatatc gctcttcaat tcttcccagg agaagaaaaa
     8401 gatgcagagg aagtagcaaa atacgtgaaa gatgcaggac gtaagattgt cttactacct
     8461 tttgatcttc gtgacgaaca agcacctaaa gaaatcatag ataaagccgt gagtgaactt
     8521 ggcgggctag atacgatggt actaaacgca ggacagcaaa tttcttgtca gtctattgct
     8581 gagttaccac ttgagcaagt caaagacaca tttatgataa acatcatcgc tatgtttgct
     8641 ttagtgaaag aagctgttcc gcatatccca gcaggaggag caatcgtaac aacaacttct
     8701 gttcaagcat tcaatccaag cgaacattta ttagattacg cagcaacaaa agcttcaatc
     8761 gctaacttta cgatcggttt agcaaaacag cttgcaccta aaggaatccg tgtaaatggt
     8821 gtagcacctg gtccaatctg gacaccatta caactagacg aaggacaacc ttctgattcg
     8881 atccctgaat ttggtcagca aagtttacta gaacgtgcag gtcagccagg agaattagca
     8941 ccagtttatg ttttcttagc atcgaataaa gcaagttatg ttacagccca aatttacgga
     9001 gtaactggtg gagaagcgat caacttataa gaagttgatc gtttcacccc tatgaggagg
     9061 tgcgaaaatg aataaaggtg taaaaacgat cggagtgatc ggaacattac ttttgctatc
     9121 tgtgcttttg tttgcgatac tattaagtgc aacctatcca ttgccttttc agctagagaa
     9181 gtttcgattc ttttccatca ctaattcata cgtgcaacaa tatgtatttt ggcttgccgt
     9241 tgcatttgct attttgacaa ttatcacgtt acttgttttc ctgttttatc caaaaacaat
     9301 cggaaacttt ctactgaaac atggtgatgg ggagttgacg ttggataaaa aagcaattga
     9361 aggaatggtt cgttctcact tgcatgaaga tgaattcatc cattcaccaa aagtaaatgt
     9421 caaagcaacg aaaaacaaga tcgccgtcaa tgtaaaaggg gagttgaaac gaacttcagc
     9481 actcattggt aaaacaggaa cattgatgaa agaaatcgaa aatgaagtac aacacatatt
     9541 gggaacaaaa gagccagtga aagtatcggt gaaatacaca ggctttgaag aaccagctaa
     9601 acgaagcaat gaccgcaaac gagtagaata gggggggacc aaaaatgaaa gaactatttt
     9661 cgacatacaa gctccctatc atctttgggg tacttggatt gatattagcc gttttatgga
     9721 tcaccgtggg ctttttcaag accttattga tcttgatcat ggcagcgatc ggcgtcgcta
     9781 tcggttttta tctgaaacaa acgaaaatct tagatcacta ttttaaatct taggaggaaa
     9841 catccatgaa taacaataac aaaaataata acaataaaat gaacaaccaa aaaccagtgt
     9901 ctgcacatcc agacccaacg acaccaaacc aatcaaatgg tgtgaacgat gaaaagaaca
     9961 aaacagcacc agtatctgca catccatatc cagtagtccc taacgttcaa caaggagtag
    10021 aagagaagaa acatgatgca gaaaagcatg cacctcatca tccaggaact ccagaatcta
    10081 aagttccaga acaacatgat gcaatcgatc cttctaaacc tgtggaagag caaaaacatc
    10141 cttctgacca tgcgaaagca caagaaaaac ttagttctga ccacacaaac ggacaaggaa
    10201 aacttggttc tgatcataca aataaccaag gaaagcatga ttctgaacag gaagattcaa
    10261 tgcgcggtga gctgaattat gaagataaag ttgtgcaaaa aatcatcgga atcgcaattg
    10321 aacaagtaga cggtttatta tctgcaaacg gtggtttctt ctctaatgtg gcaggaaaac
    10381 ttgtgaatac agataatgta acggctggga tcgaaacaga agtcggtaaa aaacaagtag
    10441 cagttgatat ggatgtcatt gtggaatatg gcaaagatat cgaaaaaatc tttgaagaaa
    10501 tgcaagaagt aatcggcaaa gaagtaaaaa atatgacaca tttagaagtg atcgaagtca
    10561 acgctaacgt agtggacatc aaaacaaaag aagaatttga aaaagatcaa gaaacggtgc
    10621 aagacaaagt aactgacgca gcgaaaaaaa ccggtgaatt tgcttcgaat caaacagata
    10681 aagtaaaatc agcagctgga agcggcgcac aaaaagtaaa agaaaataca gaaccacggg
    10741 ttcagtaata aggaagtaaa acattaggag gaacgaaaca tgggatttat ttggtcactt
    10801 atcgtcggag gaattatcgg agcaattgca ggagcaatca cgaataaagg ttcttcgatg
    10861 gggattattg caaatgtcgt agcaggttta gttggatcag cacttggtca agcattatta
    10921 ggttcttggg gaccaagtat tgcaggaatg gcaatcgtgc catcattgat tggtgccatc
    10981 attttagtac taatcgtatc attctttgct cgaaaactgt aaaaagactt ttaaaaagag
    11041 gtcgtgaaaa agctgttctt catcaagtaa taagaacagc caaacaaaaa tagcttctca
    11101 tatttttcat ttggttgggc atattatcga agatgcaagc ttttgaacac tgtttatacg
    11161 gaataagagg ctgtgacaag acttttgtca cagcctctta tttatgcggg caaattccca
    11221 attagatttt taaaagtttt tccttaaatg tgtctttatt gatacagaga agcttcttta
    11281 ataaaacaat gcctccctaa attttcttga gataggaaag gtgaacatac aaaataatac
    11341 gaccactttg aaaacccaga tgatccacaa atggatcgta tgatactgat gaagtaaaaa
    11401 gcaatggatc agaaactcaa agagattgaa aaagacaagg aagaaataat atctcttttt
    11461 tactcttgtc tgttttagcc aataatagct cgtaaagtaa tctagacaaa caaatagaag
    11521 taaacaaagt ttcgtaagag cagcaatcgt atcatgttgc tctgctagac gattgacgag
    11581 caggaaaaat gttggtaatg gaatatagat cacgagtaat gaaagaaaaa agtaaacaat
    11641 aaatggcata ctattcctcc taattgtgtg agttcgccct cattttaaaa taacgatatt
    11701 tgtttgtgaa gctttttcgt gtcgtaacaa atgttatcta atgtattttt aaataaataa
    11761 tcattattat caaaataatg
//
LOCUS       DBBGSP010000087        11508 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000087 DBBGSP010000000
VERSION     DBBGSP010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.087"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(80..2155)
                     /gene="glyS"
                     /locus_tag="ACIZE9_002787"
     CDS             complement(80..2155)
                     /gene="glyS"
                     /locus_tag="ACIZE9_002787"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGC6094594.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDIKTDRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKDHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEV
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2157..3074)
                     /gene="glyQ"
                     /locus_tag="ACIZE9_002788"
     CDS             complement(2157..3074)
                     /gene="glyQ"
                     /locus_tag="ACIZE9_002788"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGC6094595.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRF
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARSVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(3458..4270)
                     /gene="recO"
                     /locus_tag="ACIZE9_002789"
     CDS             complement(3458..4270)
                     /gene="recO"
                     /locus_tag="ACIZE9_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGC6094596.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFLSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHAYPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKMPEKNMPEKEIPEKEE"
     gene            complement(4413..5312)
                     /gene="era"
                     /locus_tag="ACIZE9_002790"
     CDS             complement(4413..5312)
                     /gene="era"
                     /locus_tag="ACIZE9_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGC6094597.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYTALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5327..5722)
                     /locus_tag="ACIZE9_002791"
     CDS             complement(5327..5722)
                     /locus_tag="ACIZE9_002791"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGC6094598.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQIDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5706..6182)
                     /gene="ybeY"
                     /locus_tag="ACIZE9_002792"
     CDS             complement(5706..6182)
                     /gene="ybeY"
                     /locus_tag="ACIZE9_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGC6094599.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6199..8391)
                     /locus_tag="ACIZE9_002793"
     CDS             complement(6199..8391)
                     /locus_tag="ACIZE9_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HGC6094600.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNTGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8415..9386)
                     /locus_tag="ACIZE9_002794"
     CDS             complement(8415..9386)
                     /locus_tag="ACIZE9_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGC6094601.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10091..11470
                     /gene="brnQ"
                     /locus_tag="ACIZE9_002795"
     CDS             10091..11470
                     /gene="brnQ"
                     /locus_tag="ACIZE9_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGC6094602.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT         3106 a         2419 c         2103 g         3880 t
ORIGIN      
        1 gttatttata tttataacaa ataaaccaga gaaatagcct attttgtgcc tgttctctgg
       61 tttatttaca tattagaaat tattttgtga tgatttgatc taaacttgct agtgacaaag
      121 ccatggcagc aatttgactt aattgcgtta atcggttctt acgtactgct ggttcttctg
      181 ccatgaccat cgtctgatca aaataatttt cgatcagtgg gcgaaggctt acaagctgat
      241 cataattttc gttgatcgtt tggtcagcaa agcttgtttt cattacctct actgctttgt
      301 gcagttcttt ctccgcttcg ttttcgaaca gttcagggtc tacttctgat tgtttttcaa
      361 gctccgcttt tttcgctaag ttcacgacac gtgtcaaagc ttccatcgat ggtttgaagt
      421 cttcatctgc aagatgctgc ttgaacaatt gtgctgctgc aaatactttt gtcagatctt
      481 tttgttctgc gttcaaaaca gcttcgatga catcatgacg gatattcttc gttgtcaata
      541 attggcgcag acggcctttg ataaagtcga tcacctgttg ttgtcccgct gacaagccaa
      601 tgccaaaacg atccgtatct ttactgataa cttcactaat cgtttcttgc agaacagaca
      661 aaggaaaggc ccattttttc gattcgatga ttcgaacgac accatatgct tgacggcgca
      721 aagcatatgg atcgtttgag ccacttggga tcatcccaac tgcaaagaaa gaaaagatac
      781 tatctaattt atcagcaatc gctaaaacag aacctactgt agtctcaggt aaatctcctt
      841 cactggatat aggcatgtaa tgttcacgga tcgctgttgc tacggctggt ttctcgcctt
      901 taagcagagc atatttttct cccatgatcc cttgtagttc agggaattct cctaccatgt
      961 tggttactag atcaaattta tagatttcag cagcgcgttg cagatccatc aattcttcct
     1021 cagacagtcc tacttgttcg cctatgatgc gagcgatgac ttgtacccgt tgcattttct
     1081 catagatgct accgattttt tcatggaaag taacagtttt taatttttca acgtattggt
     1141 cgattgaagc tttcttgtct tcattataaa agaattccgc atcttctaaa cgagcagtca
     1201 atactttttg attgcctcgt accacatttt ccaattttac ccgatcgcca ttacgagcag
     1261 aaataaaatg aggaagcaac ataccttgat cgttccgtac ttcgaaataa cgttgatgtt
     1321 ctttcataga agtgactagt acttcttcag gaacagatag atatttttct tcgaagtcgc
     1381 cagaaaagac agttggatat tcgactagat tgttgacttc ttctagtaaa tcttcatcta
     1441 gatcaatgat ccagtgatct ttttctgcta attcgtttgc ttgtgtgatg atcatttctt
     1501 ttcttttttg cggtgaagca ataacaaatt gttcatttaa tttttcttcg tattcttttg
     1561 catgcgcaaa tgtcacatct tcgcctaaga aacgatgacc tcttgaagct ctgtctgttt
     1621 tgatatccaa gatctcaaac gggattactt cgtcatctaa caatgccacg atccagtgaa
     1681 taggacggat atattcaaaa tcgtattctg cccaatgcat cgttactggg aaagtgaggc
     1741 ttttaatgac atctgctaaa cctgtcaata cttcttttgc ttctttgccg tgagtgtatt
     1801 tcgttacata gacatattcc acgcctttta attctctaaa agtgatagca tctgtcgtca
     1861 gaccttgtcc gcggacaaat ccttccgctg ctttcgtcca gtttccatct gcgtccaaag
     1921 caattttttt ggctggtcct ttgacttctt cttcactgtc tgcttgacgt tctggaatgt
     1981 ttgttacttt gattgctaaa cggcgcggtg tagaaaatgt ttcaatcgta tcataagtca
     2041 attggttttc atctaaaaat tttgctgttt tttcttctaa ttgtttcatg cttggtgtga
     2101 caacatgagc aggcatttct tccagcccaa tttcaagtaa taagtctttt gccatcttat
     2161 tcagcctcct tcacgttttc tggatttgct gtgtttttat tcaataaagg gaatcctaat
     2221 ttttcgcgtt ctgccacaaa gattttggct acagaacgag ccatgttgcg gatacgggaa
     2281 agataacctg cacgctccgt tacggatact gcaccgcggg catctaataa attgaatgta
     2341 tggctgcatt tcaaaatata atcatacgct ggatgaacaa gattttcatc gatacagcgt
     2401 ttagcttctt tttcaaaacg atcaaagttg cttagtagca agtcttggtc gcttacttca
     2461 aaagaatatt tggaatgttc atattctggt tgtttgaaga tctcgccata tttcacgcca
     2521 tcagcccatt ctaagtcata gacactttca acttcttgaa tatatgaagc aagacgttct
     2581 agtccataag taatctcaga agtaactggt ttacaaggta gtcctccgac ttgctggaag
     2641 tacgtgaatt gtgtaatctc catcccatca agccatactt cccaacccac accggcacaa
     2701 cccatcgatg ggttctccca gttgtcttca acaaaacgaa tatcgtgttc taatggatca
     2761 attcctaaaa aacgcaagct ttctaaataa agctcttgga tattttcagg tgaaggtttc
     2821 attacgactt gaaattgatg atgctgatac aaacggtttg ggttttctcc ataacgcccg
     2881 tcagctggtc ggcgggatgg ctctacataa gcagcattcc atggttccgg tccgattgcc
     2941 cgtaagaatg tatatgggct catcgtacct gctccttttt ctgtatcata agcttgcatc
     3001 agcatgcagc cgtttgatga ccaaaatttt tgtaatgtta aaatcatatc ttggacggtc
     3061 aattttttac tcatctgttt tgcccctttc aatttttaag cgttgctgtc aataagaata
     3121 caggaaagaa aacgacaaaa agtccctatg tctgattaca gacataggga cgaataattt
     3181 cgcggttcca ccctacttcc gaataaagat tcggcagctt catttatcgt actcgcaagt
     3241 gcctcttcaa aaatcgtttg ggtccggctt ccactctccc gaactcgcta aaccacgtgt
     3301 tttttactga tcttggtcaa tgtacgtatt cattttgcag ttttcttgtt tatataatag
     3361 atcctctcag tgaacgatct atttaatcta cggttaataa tagacggaag tccctgtatt
     3421 tgtcaaatag ttttgatttt tttgttgtat ctttcattta ttcttctttt tcaggtatct
     3481 ctttttcagg catatttttc tctggcatct ttaatacgtg tgcccaagac ttcatttgat
     3541 caatgaactt tttgcttttt agatgaatac cgacatattc atcatacaac tggtcaatga
     3601 ggtcacggat tgcctgcttc gtttcttctt tcaagtggat tccactgatc ttatcataag
     3661 aaatagccga aaacattcga acgaaataaa cagcgcgagg atatgcatga taacggtgtt
     3721 cgtccattgg ccagtgtttc tcgcatatca cgccgccata tttggaagaa tagtcaaatt
     3781 ttccttttgt ttccccgcat acgacacagt gcgtccaaat tggcgcgatt ccgaagcgtt
     3841 gcagtatttg aacttcaaag atattcgtga tgatttctgc atcatctcct tggtccatcc
     3901 gctgcagagc ttgttgcgta aattggaata agtgcgggtc atattgatga tcttcgattg
     3961 ctgcatctac tagatttagc aaatacgtac cataaccgct caaaaagata tcttcttgga
     4021 tgttccgaaa cgcatggacg tctttgacac tgcttaaaaa cgacaaacct tcacttagaa
     4081 aattaccgat atagactgct tcggtaaagg ggagcaaagc cggagctaat ggctgatttt
     4141 gccgatggat tcctttgata taaaacatca ttttgccaga agattccgta aagattttga
     4201 ctaatttatc tttttctttg taattacggc tagataaaat caagcctttc gattctgcaa
     4261 gctggctcat attctccctc ctaaaaaata aatctggaaa agcagattct gccgatccag
     4321 attatttatg ttacgatctt tcgctgtttt tctcaacgta cggattttta tccagtttat
     4381 ttctatacct aacctataag aagtccagaa tatcagtact cgtcttttcg gtagccgaag
     4441 tcttgcagat agactttttt gtctcgccag tctttttgga ctttgaccca aagttctaga
     4501 aatactttgt ctcctaaaag attttcgata tcctttcttg ctttcgttcc tacttgcttc
     4561 agcatttttc cacctttgcc gataatgatt cctttttggc tatctctttc aacgatgatc
     4621 gtggcctgga tatggatttt atcattctcg tttcgcttca tcgaatcaac aacgactgcg
     4681 acagaatgag gcacttcgtc tcgtgttaaa aacaagactt tctcacggat caattcagaa
     4741 acgatgaagt attcaggatg atcagtcact tgatcatctg gaaaatattg tgggccctct
     4801 ggcatttcac tgactaatac atccattaag cgttcgacat tgtttccttc tgtagcagag
     4861 atcggaatca cttgtgcaaa aggcatctgc gtcgaataat cttcgatgat tcccagcaac
     4921 tcgtctggat ggatcttatc gattttattg ataatcagat aaactggaga atgcacgttt
     4981 tttagacgtt caataataaa atcgtctccc cggccgcgtt tttgatcagc actgatcata
     5041 aataagactg catccacttc tttcaacgca gtgtaagctg cttctaccat aaaatctcct
     5101 agacgatgct ttggtttatg gattcctggt gtatcgataa aaatcagctg agcttctggt
     5161 gtagtatata ctccttggat tttatttcta gttgtctgtg ccttgtcact cataatggca
     5221 attttttgac ccacgattcg gttcaataat gtggattttc ctacattcgg gcggccgacg
     5281 attgcgacaa accctgattt atgttctggc atatacgttc tcctttttaa ttaaacaaca
     5341 aatgatatat tttagggaca aataaaatca acccaatgat gacagcaaaa caagcggtca
     5401 ctaaaactgc tccagctgcc atatctttga tttttttccc aatcggatga aaatgaaaat
     5461 ccgtaaacat gtccactaca ttttcaaaaa cagtattgat gatctctact atccaaacga
     5521 gaaaaacagc taaaagcagc cataaccact ctatccgatc aatctggaaa atcacgccca
     5581 taaataaagc aaggataccg aacgcaacat gtttcctcat attgcgttct tcctcaaaaa
     5641 cggttttgac tccttggaca gcaaattcca cggacatcag gaaatgtttg tttttctcta
     5701 cgtttttatc ttttgagtcc ataggcatcc aagatctctt tctgtaaacc aaacatttct
     5761 ttctcatctt ctggtgtcat atggtcatac ccgttgatat gcaagaatcc atgtaccgct
     5821 aaaaagccaa gttcccgatc atatgaatgg ccgtaagctt ctgcttgttc agcagcacgt
     5881 tcaatagaga tcatgatgtc tcctagtaca cgaggcaatg gattctctcc atcttcaaaa
     5941 atcactggga tttcgtcttc gccttcttct tccagagcaa aactgatgac gtctgtcggt
     6001 gcatcttttc cacggtaatc acgattgatt acttggattg ccgcattgtc catgaaagta
     6061 acagacattt ctgtttcctc tggcagcttt aaataagatg ctgcaaattg cagcaagtca
     6121 tcgatttctt tcattttctc ttctgagact tggtttgttt catccataaa ggtaatatcc
     6181 attatacatc gcttctttct attcttcttg ttcttccttt atcttctcaa cttctgtttt
     6241 cattttagga tatttgatcc gagaatggaa ggtgctactt aaaccgctga tcaatgattt
     6301 ttccactttt cggatttctt tcaaggtcaa tccactatcg tctaattgac catcggaaat
     6361 acgctcttcg ataagattat ggacaaaact ttcgattttt tcgctcgttg gatgatccat
     6421 tgcccgtact gcagcctcac aactgtcagc aatattgacg atccctgctt cacgactttg
     6481 cggttttggt ccaggataac ggaattgctc ttctgttact tccggattgc gttctttcgc
     6541 tttgatgtag aaataacgca ttagcgtggt tccatgatgc tgtttgcaaa tatcgatcac
     6601 catttgcggc atattataat cttccaatat tttggctcca tctgtcacat gtccaaagat
     6661 aatatgttta ctgtcttctg gcaataagaa attgtgcggg ttttccgctc ctgaaggcaa
     6721 gttctcaacg aaaaagctag catgtttgat cttgccgata tcatgataat agcaagctac
     6781 tcgagttagt aaagaacgtc cgccgatttc tgctacagcg ttagcactta gattagctac
     6841 catcatacta tgatgatacg tacctggcgc ttcttccagc aactgtttca ataaaggatg
     6901 atttggattg ctgagttcat ttaatacaat tacactgtca tcattgacca tcaattcaat
     6961 atatgggtgt agaccgatcg tcagcaagaa tgagaagagt gcaccagtga acccgcagac
     7021 aagcattaac caagtcgttg catcaccaaa gctcattcct tgatagacga tcaaaatgac
     7081 atccatcatc acaggaaaaa taatgaccca catggcagca gataatcctt gttctgagat
     7141 ccgtttacgt ctgacaatcg ttgccatgag cccagagaaa acataagaca tcaagataat
     7201 cgttagaaag ttcgtgccaa tcgaatcata aaaaatgaaa agtgcggata ctgcttggaa
     7261 aataccagcc atgatccctg ctcttcgatt caagaaaaag cttaaaacaa gtggtgcaaa
     7321 agcagcggga taaaacagcg ggatataagt agcttgttcc gtttggaata attggaaaaa
     7381 tttcatcagc actatgctga ctgacatagc tgtcacatag aaaagaacgt attttgttct
     7441 ttctcctgta ttttggaatt gaagtgaatt ataaatcagt acgccgattt gaagcaaaac
     7501 agctaaaacc atggcaatta gcggaaaaat cgaagttgtt tgattagtca gtcctagtaa
     7561 ttccaatttt ttcatagctg aagcatcaat ttgattacct tcacgaacaa tgatttctcc
     7621 ttggaagatc atcactggtt gtacagcttc tcgtgcggat tgtttcaatt cttctgtctt
     7681 tttctcattc aatacgtcat tcactacgat accttgatcc actaagtagc gaatcatttg
     7741 ttgttgtgct ggtgtgacat tcaaatattg gatttgctct tctgcttctt gtttaaaagc
     7801 ttccaattca ctttcacgaa cttgtttgct catctgttcg tcaatgagct tcagactctc
     7861 atccctcaca gtatgaatct cagtttcagt catttcaaat atcgtcgaat aaaaattgtt
     7921 cggtagtttt tgataaaaca caacattttc tgcattcaca ttttcaaaat ttttcttcag
     7981 cgcggcgatc cgctcttctg tagtaggctt tgggatattt tcatcttcct ttgccttatc
     8041 aatcttttcg tcataagatt tgttgatggc atcattcgtc ttatcgatca attcaaatag
     8101 ttgcttgatc cgattgttct ggtcatctgc aagatctttt tggtaagtgt attctggagt
     8161 gactgcttct gctgccagtt ttcttttttg ttcggtttct tccgtgttct cgatcgtttt
     8221 gttcgcacgg atactttctt ctgctacttg gccttctctg aaatcattgg ccttttgttt
     8281 gacactacta aatgtaacgc cgcagataat gataaaaaac aagaacagca ggaaaggcaa
     8341 tgctgccttt ccaagttttt cttgtagttt ctgcagtgtt ttattcaaca tgtgcttatc
     8401 ctcctaagca aagcttattc ttgatggaga tctgcctttt cataagcttt gatgatttcg
     8461 gcaactacag ggtgccgaac aacgtcactt gcttcaaaat taacaaaatc gattttcttg
     8521 atttgcttta atgttcgttc tgcatgaaca agaccacttg ttgtccctcg aggcagatca
     8581 atctgactcg tatctccatt gacaatcatt tttgattgat aaccaagacg tgtcaggaac
     8641 attttcatct gagcaactgt cgtgttctgt gcttcatcca aaataacgaa tgcatcatcc
     8701 aatgtccgcc cccgcatgta agctaaagga gcaatttcga tcacgcctcg ttccatcaat
     8761 cggttcgtat gatctaatcc aaaaatttgg tataaagcat cataaacagg acgcagataa
     8821 ggatctactt tttcttttag atccccggga agaaagccta gattttcccc tgcttccaca
     8881 gcaggccgcg tcaaaatgat tttttgcact tcaccttttt tcaaggcagc gattgctaat
     8941 actactgcaa gaaaagtttt tcctgtcccg gctggtccta cgccaaatac gatatcatgt
     9001 ttggctaccg attcgacata tttcttttgg ccgctgtttt ttacccgtat aggttttcca
     9061 ttacggtctt tgacgatctc ttcctcatac atctcaacaa aataatctaa tgtgcctttt
     9121 tgccccattt tcagtgccgt cacgacatct ggtgtactta catggattcc tcgtttgatc
     9181 aattcctgca atgtccgaat gactgaggca gccaaggaaa tctgggattg ttcgccaatg
     9241 atctgaatga tttctccacg tgtatggatg gttgtttctg ttgtttcttc aatcagtttt
     9301 atgtgcttgt cgtgtgcacc taaaagcatg ctgacatcat cagcagccgt caatctaatc
     9361 tctaaagaac tagactcttc cgtcaaaaat agacatcccc tttttttcga ttcattcttt
     9421 cctattttac catactcaga agaaactata tagcaaataa gaaaaggttc taaaagagtt
     9481 gcttaaccat aagtaccaag aaacgttaaa aaatagctgc ttccattctc taaaggtctc
     9541 gtttgaataa aaaaagctga tcatgtaagc tatgcataag atagaggaca agtattccgt
     9601 ctaacttagc aagtattctc tgggtatttt tcttgtttca aaaaaagaaa acaaaatatt
     9661 tgaaatattc ttgcatttca aaaaaaacag gtgtattata acgtcaacaa ataaatatac
     9721 agcaaagcgt cgaggaaaac agtaggctat tcagtgattt attcccagtg agtcatgtaa
     9781 gtgagaaatg acaataaatc gaatagacga acatcatttc cgagtcaatg tcgaaaacgt
     9841 agatcattgt ggctgcctcc attatcaggc cagcggataa ctttatcgaa aagcgtccgt
     9901 gaatgaagaa gcttttttaa gcgaaaaaag gtggtaccgt tctagaatct agagcccttt
     9961 tcccaagtgg aaaagggctt tttttatatt ttaaggtggt ggttttcatg gaatctgata
    10021 ttagtggtat ttctagtttc tgcaacgttt attttgttac tcaaaatgat aattattgga
    10081 ggaaaaattt atggaagaaa caaaaactta ttcatggaag caattattga tggtcagttc
    10141 acttatcttc gggatgttct tcgggtcagg taatctgatc tttcctgtcc acttaggtca
    10201 aatggctgga tcaaactgga tcagcgctgg tgtaggattt gccatctcag gcgctctttt
    10261 cccattatta gctatcttag ctgtagtagt gacaaaaagt gatggtctgt atgacttagc
    10321 taaacctgtc ggaaaatggt atgctgcctt gttcttgatc cttgttcatt taacgatcgg
    10381 accattcttt ggtacaccgc ggacagcagc aactgctttt gaaatggctg ctaaaccctt
    10441 tttgcctgaa aaatatgatt cattaggtat gtttttattc tctgctcttt tctttttact
    10501 tgcttatttc cttactgtac atccaacacg tttggtcaaa tatgtcggaa agtatttaaa
    10561 ctccttgttt cttgcattat tagctatcat ttttgtcgtt tctttattcc aacccatggg
    10621 gaatctaaac caatctgctg cagattctta tcagacgaac gctttgacaa atggcgtttt
    10681 agaaggatac aacacggttg atgcagtagc tttacttgct ttaagtgtca cttttgtcca
    10741 tgcagttcgt gatcttggtt ttaaagataa aaaagtcaca gaattaacag caaaagctgg
    10801 tagcctgagc gttgcgttag aagtcatgat ttattttggt ctggtccttc tcggtgcgat
    10861 gagtttgaat aagatgtctt tatcagaaaa tggcggaact gcactttctc agatcactaa
    10921 tttttattta ggtaacttcg gtgctagctt cttaggggta atggtcacat taggtgtctt
    10981 cactaccgct atgggactcg ttgtttcttt tgcacaagat ttccataaac tgttccctaa
    11041 agtcagttat atgacatggc tgcggttaac gacttttgtc tcttttgtcg ttgcgaatgc
    11101 cggattggat aatatcatcc aatggtcttt accagtattg atgcttttgt atccattgtc
    11161 acttgcgtta atcttgcttt ccttaacagc aaaattcttc caaaagagtc catttgtcta
    11221 tcaagtaacg atgttctttt ctgccgttcc agccgtattg gatatgttgg caaattcgcc
    11281 tgcattagtg agtcagcaaa ctgtcgtagc aagcttacta ggattttatc atcattatgt
    11341 tccttttgct gcattaggac ttggctgggt cgtcccaacg ttgcttggtt acgctggcag
    11401 cttgctcttt tattatgtat atcgcgtatc aggatataaa caagaagcaa gtgagttacc
    11461 agaagaataa ccaaatcaaa cacaatttaa cataagagat attaaaca
//
LOCUS       DBBGSP010000088        10510 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000088 DBBGSP010000000
VERSION     DBBGSP010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.088"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(220..972)
                     /locus_tag="ACIZE9_002796"
     CDS             complement(220..972)
                     /locus_tag="ACIZE9_002796"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGC6094603.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            1085..2005
                     /locus_tag="ACIZE9_002797"
     CDS             1085..2005
                     /locus_tag="ACIZE9_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC6094604.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2078..3013
                     /gene="murB"
                     /locus_tag="ACIZE9_002798"
     CDS             2078..3013
                     /gene="murB"
                     /locus_tag="ACIZE9_002798"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGC6094605.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            3311..4789
                     /locus_tag="ACIZE9_002799"
     CDS             3311..4789
                     /locus_tag="ACIZE9_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094606.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            5066..7126
                     /locus_tag="ACIZE9_002800"
     CDS             5066..7126
                     /locus_tag="ACIZE9_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGC6094607.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            7209..7778
                     /locus_tag="ACIZE9_002801"
     CDS             7209..7778
                     /locus_tag="ACIZE9_002801"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6094608.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKSDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(7953..8759)
                     /locus_tag="ACIZE9_002802"
     CDS             complement(7953..8759)
                     /locus_tag="ACIZE9_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094609.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            8897..10411
                     /locus_tag="ACIZE9_002803"
     CDS             8897..10411
                     /locus_tag="ACIZE9_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HGC6094610.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
BASE COUNT         3727 a         1751 c         2071 g         2961 t
ORIGIN      
        1 atctgcggta ataagcccaa ccaaacgaaa aatatgagga actatttttg tttggctgtt
       61 cttattactt gatgcaggac agctttttca caatctctcg ataaacagtg ttcaaaagcc
      121 agtttctcgg tattatgcca aatttatgca aaatgtggaa agccattttc acaaaatttt
      181 tcttaatact cgaaactaaa cgactttttc acaacctctt tatttcaaat ctaattctac
      241 tggacaatga tcactgccca taatgtccgt atggatcttt gcatcagcta gtcctggctc
      301 taaatctttg ctcgtcaaaa agtaatcgat ccgccaacca gcattgtttt tccttgaatt
      361 gaatcggtag ttccaccaag agtagacacc ttcctgggtt ggataaaaat aacggaatgt
      421 atcgataaac ccgttatcca acagtcgaga aagagccgct ctttcttctg gagtgaatcc
      481 agcatttttt tgattcgttt tccagttttt caaatcaatc ttttgatgag cgacatttag
      541 atccccacac acgatgactg gtttttgttt ttttagattt tccaaataat tataaaaggc
      601 ttcttcccat tctaatcggt aatctaaacg ttttaattcg ctttgagaat ttggcgtgta
      661 acaggttaca agaaagaaat cggaatattc caaagtaatc agacggcctt ctgtatcatg
      721 gatatcgata cccattccgt aagtggcatt caatgctggt tttttagcaa aaatcgctgt
      781 gccggaatag ccttttcgtt ccgcgtaatt ccaatattga taataacctg gaagatctaa
      841 atcaatttgt cctgcttgga gtttcgtttc ctgcagacag aaaaaatcgg cgtctaactc
      901 atgaaaaact tctaaaaaat ttttatttac gatggcacga agcccgttta cgttccaaga
      961 gataaatttc aataaaagca cactccttcg aattaatttc cttacctttg cgatactatt
     1021 gtacctcatt ttagaaaaaa atggtgtaag atgaaagtaa ctaaatgatc caggaggaaa
     1081 gtagatgaag attggtgtaa tcggtgtagg gaatatcgca gaaaaagcat atttaccaac
     1141 ttatgcgaaa aaacaaggaa cacttgattt ttattttgca acaagaaata aagaaacaaa
     1201 agaaagaatt caaaaagagt acgggttcca acatctatat gaaacgatcg atgagctttt
     1261 agaagaaaaa atcgaagcat gtatgatcca cgcagcaaca aaagtacatt atgaattagc
     1321 caaaaaatgt ctagaaaatg gtatccatgt ttatattgac aaaccactga gtgtccatct
     1381 aaatgaagtt cgtgaattgc aagaattagc tgataagaac caaataattt tgatgatcgg
     1441 tttcaaccgg cgctttgctc ctatggtaga agaattgaaa cgtatcccag ataagcggtt
     1501 gatccacctg caaaaaaatc gaatagcggc aaaagaaacg acagagttcg tcctttatga
     1561 tttgttttta catcttattg atacagctgt gtatttatta gatgaaccca ttttgagaac
     1621 aaaataccag ataagagaaa caaaggaatt tttggaatat gccattttac aattagaaac
     1681 acaaaatcaa acggctattt taacgatgga tttagcaagt ggcgctaata tagaaaaata
     1741 tcaagtaaca agtaaaaatg gtacttatga agtaaacgat ctgacccagc ttgtcattca
     1801 agatgctgat ggaaaaaaag tgaaagaatt tggcgactgg acaaacacgc tagtcaaacg
     1861 cgggtttgag ccaatggtag aggccttctt ttctcagatc cgtttaggta aatcggaaac
     1921 agaattgctt aaacaaaaag aagttgtaag aagtcatgaa ttatgtgagg aagtgcttaa
     1981 agatcactac cgtcatcaac tttgaacaag actggcaaga ttgtattaag cgtgatagaa
     2041 taatgaggac gtttgagaaa agaaaggaaa atcctcagtg aataaagaag aaatagttga
     2101 aagcttagcc acgattacta tattgtttga tgaaccattg atgaactata cgtttacgaa
     2161 aacaggtgga ccagctgatg tccttgcatt cccgaaaaaa caagaagaag taaagcaaat
     2221 catcgattat tgccgaatcc atgatatacc ttggatggta ttaggaaatg caagcaatct
     2281 gatcgttcaa gatggcggga ttcgcggtgt agtcatcatg ctgactgaaa tgaaacagat
     2341 tcatgtcaaa ggaacgatgg tcattgcgga agcaggtgcc tcactgattg atacgactta
     2401 tgcagctttg gcagaatcat tgactggatt tgaatttgct tgcggcatcc cgggaagtgt
     2461 cggtggagcg gtttatatga atgcaggtgc gtatggcgga gagatcaaag atgtttttgc
     2521 tgaagtggat cttttgcttg aagatggaac attgaaaact ttgacaaaag acgaaatggt
     2581 attttcttat cgtcacagta aagtccaaga attacgtgct atcgtattgg aagctcgatt
     2641 cagtttgcaa acaggggatt atgaagcaat caaagcaaga atggatgagt tgaccgaatt
     2701 gcgtcaatca aaacagccat tagaataccc ttcatgcgga agtgtcttta agcgcccagt
     2761 aggacactat acaggtcagc tgatccaaca agcaggattg caaggcctga aatggggcgg
     2821 tgcacaagtc tctgaaaaac atgctggatt catcgtcaat atcgatcatg cgacagcgac
     2881 agattatatt gaattgattg cgcacatcca agaagtaatc aaagaaaaat ttgatgtgtc
     2941 tttagaaaca gaagtgcgga tcattggaga aaaacaagca atatcagaaa caagcagaag
     3001 tttagccaat taataagtaa tggaacttaa aataagtaaa agagcaggac ggtggccgtc
     3061 ctgctctttt ttgtggttgt ttacgcaaat ggcgcaaatc ttgtacattt taacacaata
     3121 aaacaaaaaa tatagaatat ttcctcataa atttttccat tttttgcaat attctcaaaa
     3181 aaaagataaa aaatgagaat aactgatgaa aaaacaagca taatccatca taaaatcagt
     3241 ataggtgaaa agatgaactt tcatctgcat atcaagtaat tggtatgagg cattttttga
     3301 ggtgtaggat atgaagttgg attaccttat agaagaggaa gatagagaaa aactgctgct
     3361 agctagatat ttagaatttg agaaaaagaa ttatgtagtg ctgcctaagt tatatgaaac
     3421 attaggtttg tctaaattta aaacaagaaa ttatatcata gaattaaata aagaatttac
     3481 tgaattcaaa acaaagccag agatccaaat ttcagaagaa gcagagatcc atgtcgaacg
     3541 tctgaatttg acggatatca aaaatttaag aagaatctac tttcaacgat caaaaattgc
     3601 tcgactgtta acggagatcg tggattcaaa agtaacgatc gaaaaatttg cagagaatca
     3661 ttttttaagc atatcaagag cctatgtaaa aagaagagaa ttagtctctt ttcttgaaca
     3721 gcatcaaata aagttaaaga aaaacatatt agttggggaa gaaataaaca tacggaacgt
     3781 attatttggg gtatatttcg gggtctttaa tggtttttct atgccattta gagaaagcgt
     3841 catgaatgaa gcaaagagta tcgtgcaata ttttgaatat ctgttcaatt taaaactgtc
     3901 tgcaacaaaa cgaatcaaat tcaatttgct aaccactatt agtttgttga gggcctatgg
     3961 gaatcaacca atcggaaaac gtttcttttc agatgaatac tttaagagct cagaaggaat
     4021 gaagatcatc aaggatttat cacatatttc ttttcttcat atccctaaag agcagatcat
     4081 tgatgagatt tcttatatca tgttgttttt gatcacggaa gaagaatttg aattagatgg
     4141 cgcatttgga cttgcggaag ctcattttca tgatatccac atgattagtc aaaaaatgtc
     4201 agtggaattg attgatcaat taccattttc gattgaaatc tctgaagaag aaagactata
     4261 tatacgaaaa gaacttcgta tgggtatgat gcatgtcaat cgaaaaaatt ggatattcga
     4321 ctttgagatg actagcttta cgtctaaaaa gcagctacag tttttcttcg agacgtatcc
     4381 aatattcagt acagcaatcc aaaaggtcat acaagagaat aaacgctatt tcttgggaaa
     4441 agatgaacgt ttcatgattc gcttatttta tgattatctc tttttattgg tcggtatttg
     4501 tccggtatca tattttgaag caccgattca tgtctgtatt gatttttcgc aaggatctgc
     4561 ttataccgat tacattattt ctcaagtgaa aggatttaaa aattacaata ttgtgattga
     4621 gagtcgaatc acttctcgta cgaatattta tttatctgat tgtttacttg aaaaatttaa
     4681 taaagaacag ataatttgga aaaatccacc gactccagat gactgggaat attttggaaa
     4741 taccatcatc agagaaaaaa atagacattt aactgaaaaa atcagctagt atttatggat
     4801 ggcagctttg tctcacatat ttattagctg atttatgttt ttttcaaaga aaaggtaact
     4861 agatataact agatataact agatatatta cttaacaaaa ttaaaaagta cataagttat
     4921 tattccgatt ttcttgaaac aataaaaaat caaaaaaaat actctcctaa tagtccatct
     4981 tcttttgatt ttatttatat aatgaaatca tcttatgaaa attactactt catgtttaga
     5041 caagagtagg gaggactaag aataaatgtg ttcaaaaaga cgttcaaaac aactaaataa
     5101 acacgcttgt cgtttagata aggaacggtc gtgttctgaa aaacactacg ttaagtttat
     5161 gatgcgcacg atgctgatca gtttatctgt aggtgtctat atgcatgtac ccgttcaggc
     5221 aacgacacaa accatcaagg tcgtacgtac ctctgtttct gagaccactg attcccctat
     5281 cactattact catactttca ctgatgcaaa tggaaaacag ctacttcctg cattgacttc
     5341 ctataataaa gtcagttatc ctccaacgat aaaccactac tggttaattc ctaacaaaac
     5401 attatggaca tcggaaaccg gaagcagtgt gccgctttct atcttttccg atatgactga
     5461 tcctacaaaa ggtgatcagt taaaacagat cactgatatt ttgaatcatg ctttgacaga
     5521 tataaaggac ggtggaagcg cacaagtttc ttatgtatat gaaaaagatt attcacagtt
     5581 tgaaagaaag aaaatcgatg ttctggcagg gacaaaagtt tcgatatctg atctggtaga
     5641 aaggctgaag aacgcagatg gaacacaagg agatatgtcc aaagtaattt caaacaatgg
     5701 gaatatcgtg gatacgacta atacaggaac atctactatt tccttgtcct attttgatcc
     5761 aattgcttta aaaacaatga ctgcatctgc tgtgatccat gttcgtgctg atcaaacagc
     5821 tatcaaagga aaagatcttc acttaagaac aggagagagt tacgccccta aagatcttgt
     5881 tgaatatgta acaaaaagcg atggaacttc aggaaataaa gaagaaatca aaatgaacgg
     5941 gacagtagat actacaactc cgggagaata tcccgttgta ttaacttata tagactcgaa
     6001 aacatcaaat gtggcagaaa caacagctgt agtttatgta gaagcatctg ctgcttcatc
     6061 gactgtcatc actcatttta tagatagtca aacaaataaa gaacttcaag cagaaacaca
     6121 tatgagtagt gtaaatcgta ttcctgattt gcgcctacct gctgaatttt ctgatcgagt
     6181 gccaaatata gatttatcga cttatgaaca aaatgggaaa gtcacttcta tttctgattg
     6241 gatgcaagca aacggattag acagaaaaag tcactggtcg gagatccttg aagtacttca
     6301 ctcagaactg atgaataata ggaagcaatc aggaggggaa attaccttta cttatgttta
     6361 tataccagac aatcgttcat tagaaggtca tgatcttatt gttcatccaa acgaaaaaat
     6421 aaacaaagaa gagttgatcc aatcagcaac aaattcctta ggtaaacccg taccgttaaa
     6481 ggatgtatcg gttacaatca atgaagtacc attggaggat ggttatttga ccaaacaaac
     6541 aggtgatttt acgattatgt atagttatca tgacccgtat tcactccaag aactccatgc
     6601 tcagtcacta ttacatgttt taccattaaa caaacagata gatcaaaaag aacaaaaaag
     6661 acaagaagaa agcttgtcag aaaaaaaaca acaaatggct catgcagttt ctccaacagg
     6721 gaaagtaaaa caaacaagaa gcctagagtt agcaagaata tctagaaaaa tctcagaatc
     6781 taataaaacg ataaggcaag aagctcattt ggccccacaa gtttctggat tggaaaatga
     6841 aattttagag cctaaaataa aacaacaatc agaaaaagaa tttgttgcta aacagtcgga
     6901 agatcagaag gaatcagatg accagaagga aacgaagaaa aaacgcttgt caactattga
     6961 ttccaccgat gagcatctgc agccgcaagt accacttcct agtccgggaa cacccgcacc
     7021 tggtggaggt attccttctt ctgctttagg agatttcatg cgaggtatgg caggaacatg
     7081 ggtatacgct aatcgaaatg aatttgacgc agatgactgg ttctgattta tatctctatc
     7141 tgttatagtc aaataagtag ctgagtcata tgttatttgg cataatggag acgaggaggg
     7201 atagaaaaat gttagataaa acgttacctt acgcagaaat ctggatgaca agaccacttc
     7261 aacaaaatgt tccaatcacg cctttagcgg aaggttttga atttcgattt tatcaaaaag
     7321 aagatgaatc tgcttgggcg gagattgaga cttccgttgg ggaatttcaa acgacagatg
     7381 aagcacttga gtattttcaa caaaactttg ctccttatcc tgaagaactt gaaagaagga
     7441 tgttttttgt agagacaaaa aaaggagaaa aagtagcaac ctgtaccgct tggcgaaaaa
     7501 aatcaagaga gcaagtgtat ccggtttttc attggttagc agtgaaatca gattaccaag
     7561 gaaaagggct cgcaaaagca ttgactgcca gagtcttgca agaatttcct accctccata
     7621 cggacggacc aatctatctt cacacacaga catggagcca tcaggcgatt gctctttata
     7681 aaaaaatggg ttttactttt attgctgaaa atctagacgg cacacctaat ccagattatg
     7741 aaaaagttat gcaggtttta agtaaattag ataaataacg aaatggtgaa ataagtcctc
     7801 agtattggga taaaaaacga aatagtcatt cctcatatct tacttttttg agttaatact
     7861 atcggataac taatggcatg ccatacattc aaaaaagaag gggcagtgac aaaagtattg
     7921 tcactgcccc ttctcttgtt ttttagcatg ttttatcgtt tgattttttt aggaataaaa
     7981 ttcttgatga acgtaaattt ttggtaatcg tttcgactat agaggtaacc aaatacactg
     8041 aaaacaactg ctccaataaa attaacaaat aaatccttca tagtatccat gattcccacg
     8101 tctaagtaac cattttggat gattgtttta tctgttttac catctgcatt ttgactttca
     8161 atgattgtcc gagtgatatc tggaacatga tagacagtgt ttccgtcttt acttaactcc
     8221 acactattga tttgctggat gatcgtatct ttttgcatat cgaattgcag taatttatct
     8281 gctgaaaatt ccacaaactc ccacataaca ccaactgtca tcgaaaaaca gaaggaaaca
     8341 actgctagta ataaaggagt caagttcatg gtttttgtat ttttattgag caaataaaca
     8401 agggaaaagc cgacaccccc agctaaaaat ccgctgaatg catgtagaaa agtatcccac
     8461 attgaaaaat agccataaaa atcacttaac tctcctaaaa ctgttgaact aaaaataaaa
     8521 gataacaaaa tgatttctag catatttgga atctgtatct ttaatatctt ttccagaaaa
     8581 taagggattt caaataaaat taatgtcagt aataaaagca ttgtatttcc ccagtgttgg
     8641 ttccagacct gatccactag cataataacg acgatgatac gtaataaaat atagattccg
     8701 tttgtgattc tacctgcagt ttttgtactg ttcgtaaaaa aggttttcaa atgattcata
     8761 aaataactcc ttcatgtata tccttaatta tactaagaag cgtgtgttta ccaaagctat
     8821 atgacttaaa gaaaaacaga gttgatattg tgaaaaaaat cacttaatat agtataagga
     8881 gaaaaggggg atacaaatga aaaaattagt tgctggttta ttaacagccg ttgcacttct
     8941 tgctatgagc gcatgcggcg cagatcagaa aaatacagcg cagacaagtt ctagtacgaa
     9001 ggaatctgcc gaagtatcat caggcgcttc tgaacaagta tatacagatc caaaagaaat
     9061 gaaagaatct tatgatgtcg tgattattgg agctggtggt gcagggatgg cagcagctat
     9121 cgaagcaaaa gatgctgggt tgaatccagt aattttggaa aagatgcctg ttgccggagg
     9181 aaacacatct aaatcatcaa gcggtatgaa tgcttcagaa acaaaatttc aaaaagaaga
     9241 aggaatcaaa gactcgaatg atgccttcta tgaagaaacg ctaaaaggtg gtggaggaac
     9301 gaatgataaa gaaatgcttc gatactttgt cgatcactct gctgatgcgg tcgattggct
     9361 agatcaaaac ggtatcaaac tggacaactt aacgatcact ggagggatga gtgaaaagag
     9421 gacacatcgt ccgtctgatg gctcggctat tggtggatac ttagtggagg ggttattgaa
     9481 taacgtccat gagcgggaaa tccctatttt tgtcaacgca gatgtgacag acattaagaa
     9541 aaatggggaa acggtcaatg aagtgactgt acatgttcaa ggagaagaac caaaagaggt
     9601 caccggaaaa gcaatcgtag ttaccacagg cggttttggt gccagcaaag aatttattga
     9661 aaaatatcgt cccgatttag ctgattatat tacgacaaat caagaaggat caactggaga
     9721 tggtatcacc atgattgaaa aattaggtgg acaaaccgtt gatatggata aaatacaaat
     9781 tcatccaact gtgcagcagg atgagggggt cttgattggt gaggttgttc gcggagaagg
     9841 agcaatcttg gtcgatcaag aggggaaaag atttgtcaat gaaatggata caagggataa
     9901 agtatctgca gcaattacag cattgcctga aaaatcagct tatttgattt ttgaccaagg
     9961 cgtgcgtgat cgtgccacag ctattgaatt ttatgaccaa aaaggatatg tcacaactgg
    10021 aaagacaatg gaagaattag cagaaaaaat cgatttacca aaagaaacac tagcaaaaac
    10081 agttgatgga tggaatacgg atgttgcgga gaaaaaagat gctcaattca accgtgccac
    10141 agccatggaa catgacttat cgtctccgaa ttattatgcg atcaaaatcg caccaggaat
    10201 ccattacacg atgggcggtg tgaaaatcaa tacgaacact gaagtattag ataaagaaaa
    10261 ccagccaatt agggggttat atgctgctgg tgaagtcaca ggtggcttac atggaaacaa
    10321 ccggatcggt ggaaattcag ttgcggagat cattattttt gggcgacaag cgggcataca
    10381 agcagctcga tttgcttcgg aaaatgaatg aaatagaacg taaataaaaa gaggttgtga
    10441 aatcagcgtt ttgagctaat accgagggtc agctgattga acactgttta gtgaagaggt
    10501 tgtgaaaaag
//
LOCUS       DBBGSP010000089        10082 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000089 DBBGSP010000000
VERSION     DBBGSP010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.089"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(109..2229)
                     /locus_tag="ACIZE9_002804"
     CDS             complement(109..2229)
                     /locus_tag="ACIZE9_002804"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HGC6094611.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="ACIZE9_002805"
     CDS             2459..3637
                     /locus_tag="ACIZE9_002805"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGC6094612.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="ACIZE9_002806"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="ACIZE9_002806"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGC6094613.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="ACIZE9_002807"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="ACIZE9_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HGC6094614.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="ACIZE9_002808"
     CDS             complement(4990..6243)
                     /locus_tag="ACIZE9_002808"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGC6094615.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="ACIZE9_002809"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="ACIZE9_002809"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGC6094616.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFISGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="ACIZE9_002810"
     CDS             7821..9167
                     /locus_tag="ACIZE9_002810"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGC6094617.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="ACIZE9_002811"
     CDS             complement(9475..9861)
                     /locus_tag="ACIZE9_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HGC6094618.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(9910..>10082)
                     /locus_tag="ACIZE9_002812"
     CDS             complement(9910..>10082)
                     /locus_tag="ACIZE9_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HGC6094619.1"
                     /translation="VETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQR
                     RFEGTLRYSLGY"
BASE COUNT         3215 a         1839 c         2053 g         2975 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt atttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttattata cccgtggtgc
     9901 tagttaattt taatatccta aagaatatct caaagttcct tcaaaacgtc gttgtgctcg
     9961 acttaataga acactgtaag ccagtaatat gctttcaaat ctactctcta gccctttaac
    10021 agaacgtgag ttgaaatttt gacaacctaa tttttctaag gaagaaaaaa cagtctcaac
    10081 tg
//
LOCUS       DBBGSP010000090         9676 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000090 DBBGSP010000000
VERSION     DBBGSP010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9676
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.090"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(203..1654)
                     /gene="cls"
                     /locus_tag="ACIZE9_002813"
     CDS             complement(203..1654)
                     /gene="cls"
                     /locus_tag="ACIZE9_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGC6094620.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            1995..4661
                     /locus_tag="ACIZE9_002814"
     CDS             1995..4661
                     /locus_tag="ACIZE9_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGC6094621.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            5025..5777
                     /locus_tag="ACIZE9_002815"
     CDS             5025..5777
                     /locus_tag="ACIZE9_002815"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6094622.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(5799..6953)
                     /locus_tag="ACIZE9_002816"
     CDS             complement(5799..6953)
                     /locus_tag="ACIZE9_002816"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGC6094623.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            7138..9579
                     /locus_tag="ACIZE9_002817"
     CDS             7138..9579
                     /locus_tag="ACIZE9_002817"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGC6094624.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         3116 a         1742 c         2075 g         2743 t
ORIGIN      
        1 gaaagaggtc gtgagcctgc cgtccagctc cgagtcacaa ggaacaagtt caaaaaacag
       61 cttctcatgt ttgttgaata ttgtgacttg tgaccgagga gttggcagga gaacaccgtt
      121 tgttcggaag aagggactgt gacaagattt ttgtcacagt ccctttaatc ttagtatatt
      181 tttctctact tgaataaaaa aattatagga ttggagaaaa taatcgagaa atttgttgct
      241 tgaataatag ccagttagac atttccttga ctgtttcagt tgtcatggat gaacaatgtg
      301 tctcatcttc tttgaactga gtagcaagtt cttctaaaaa ctcaggatcg taaatgacag
      361 cacttgtttc aaaattcaat cggtagctac gaatatcttg atttgctgaa cctaccatgc
      421 agatttcatc atccattatc aatgtttttg catggaggaa gccgttctca tagacaagga
      481 tttgtacatt ttccttgatc agctgccgag cataatattg tgttgctcga taaataaaag
      541 gatgatccgg tttgttggga atcatgattt tcacatctac accagaggca gttgcgattt
      601 ttaaagcagc aatgacactt tcatcaggaa caaggtaagg tgtctgtatc caaacacgtt
      661 ttttagcaga agtaatcaat ttgataaatg aaagcttgat ttgttccctt tcgttattcg
      721 gtccgcttga aacaagctgg atggatgtat cagcaagctt agattcatct cgatctgctt
      781 ttttaaagaa ataattcaaa tgatagccga cctttttttc ttcaggtacc gagacgttcc
      841 agtctgttaa gaagcgaagc tggagcaaag aagaagcggc accgaaaatc cgtatatgcg
      901 tatcgcgcca atagccgaat ttttttgttg tatttacata ttgattggca atattgaaac
      961 caccggtata actaatcttt ccatcgatca caacgatttt tcggtgatca tggtaattca
     1021 atcggaaacg aagtaatgcc ctttgtgagg taacaaatgt atggacatgt ccaccatttt
     1081 tgattagacg attgaaatct tttgcttttg tgccatgaga gccaaatgca tcatataata
     1141 ttcgaacttc cacgccttct gcggcttttt cttctaaaac atgtaagact tgctggccga
     1201 tattatctgt cacaaatgcg taatattcga tatggatcga atgtttggct ttttttagat
     1261 cttgaagcag tgaatccaat ttctcttgtc cgtctgtgag aagagtgaca gaattcattc
     1321 ttgtcagcgg catacgattt aatgaagaga agaagtcaac aaattgctgt ttgtctttat
     1381 cgcccatgtc aggatcgtaa tgttcaatgg tatctcctct aaaagactga aagttttcta
     1441 attctttcaa gtcactttgt cggagataga attttttctt atccgttaat ccacgtccga
     1501 aaaataaata taatacaaag cccaccccag gaagggcaaa caatactaag agccatgccc
     1561 aaatggctgc tacatctcgg ggtttgatca aaatagccac caaagcaata agtgcattta
     1621 atagataaag ggcggttata atactagata ccacaaaaat gttcctcctt acatacaata
     1681 acattagtat agcatgatag aagaaagaag cctaccaagg tgaatatact tttcactcct
     1741 ttcatgaaaa tgtaggtaaa tcgggctaaa gtagttgctt tttgtaggtt aataaggtag
     1801 gatattagta cagttgaata tctccttagg ggagtaaccg gcaacgtttg ttgcgataat
     1861 atcaacagta agttaaccaa atggttttct ggtattgtat gaaatggtga gacctaagac
     1921 aaatgcgtat ttgtcttagg tctctttttt ttcagacagg actagggcca agatcaaaaa
     1981 atgggggatg aaatttggaa aacaaggaac aagcacaaca agcggtctat aaagaaacga
     2041 tcgactcgtt gatgcagcaa acgcagagct caaccgatgg attgagcacc acgcaagcga
     2101 aggaaaaatt agaaagagat ggcttgaacc agctaaaaga aaagccgaag aagccaactt
     2161 ggaaattgtt cttagaaact ttcaaagatg caatggttat cgtattgctg attgtcgcac
     2221 tgattcagat ggtcatgggt gactacatcg aattcttagt tatttttgca gtattgatgt
     2281 tgaattctat aatcagtgtt gtccaaacaa aaaaagcaga aggttcttta gaagcgttga
     2341 aaaacctttc agcgcccgat gctcgagtga ttcgtgatgg taaggaaaaa acgattccgg
     2401 caaacgaact tgtggtagga gatatcgtgt tgttagacgc aggcgattat gtacctgctg
     2461 atggacgttt actagatgcg ggatcattaa aagtagatga aggtatgctg acaggagagt
     2521 cgacttctgc agaaaaagaa gtaacggata tcacaagtac ggtaccaatc ggagatcgta
     2581 caaatatggt attcagtgga acgatcgtaa cttacggacg cggtaaattc ttagtgactt
     2641 caactgggaa taatacggag atcggacaag ttgctggcct tttggaatca acaactgagc
     2701 aagtcactcc gttacaacga ggtctggata aattcagtaa aaaactaagt ttggctattt
     2761 tggcattgtc tttattgatt ttaggtatcc aactgtttcg tatttatctt ggagaaggta
     2821 caggagatat gactgcagat atcgtcagcg cagtgatgtt tgccgtagcc gtagccgtag
     2881 ctgctattcc agaagcatta cagtctatcg taacaatcgt gttatctttg ggaacgaata
     2941 aaatggcaaa acgtcatgcc attattcgga agcttccagc agttgaaaca cttggttcga
     3001 caagtatcat ctgtacagat aagactggta cattgacaca aaacaaaatg acagttgttg
     3061 actacttttt aggtaatggc gatactgggg atttcacaaa tgacccttca aaatggacag
     3121 ctgacgaacg tcgcttgatc gaaatcagtg ttttagcgaa tgatgcatcg atcagtgaag
     3181 acggtactaa attgggcgac cctacggaag tagcgtttat cgactttagt gaaaaattaa
     3241 accagcctta tcaggaaatc cgaaacaact acccaagaca agcagaactt ccttttgact
     3301 cagatcgaaa attaatgtct actggacaca caattgataa caaaaattac ttgtttgtta
     3361 aaggcggacc agatatcgtc ttccaacgca gtaaaaaagt attgctaaat ggtgaagtcg
     3421 ttccgatgac ggatgaattg atgaaaaaat tccaagagca aaatgaagct ttttcaacac
     3481 gcgcattacg tgtactagct tttgcttacc gtccacttga taattttgat ttatcatttg
     3541 aagatgaaga cgatttgatc cttgttggtt tgcttgctat gatcgatcct ccacgtgctg
     3601 aagtgactca ggcggtaaca gaagcaagaa gtgcaggaat caaaacaatc atgattactg
     3661 gtgaccacaa aacaacagct gttgctatcg caaaacaaat cgggattttt gaagaaggaa
     3721 acctggcttt gaccgggacg gaactagatg aattgacaga agatcaacta aacgaagttt
     3781 tagaaaaagt cactgtttat gcacgtgttt cacctgagaa taaaattcgt atcgttcgtg
     3841 cttggcaaaa taaaggtcat atctcagcta tgacaggtga tggtgtaaat gacgcaccag
     3901 cattgaaaca agcagacatc ggaattgcta tgggaacggg tacagatgtg gcaaaagatg
     3961 cagcagcgat ggtattgacg gatgataact ttgcttctat tgtcagcgca gtagaagtag
     4021 gacgtaatgt gtttgataat atcaagaaag ctatttctta tctatttgca ggaaatttag
     4081 gtgcgatcat tgcgatcatc tttgccttag ttgctgactg gtccaatcca tttacagcat
     4141 tacaactgtt gttcatcaat ttagtcaatg attcactgcc agcaattgca ttaggtacag
     4201 aaaaagctga acctgctacg atgaaccgcc cgccaagaga tccaaattca ggaatcttta
     4261 cggacaaaac attgatttct gtaacgtatc gtggtgtgct gattgggatt gctgttatct
     4321 ttgctcaatg gcttggcatg cagcattcac ctgaattcgg tgtagccatg tcattttcaa
     4381 cattgatttg gtgtcggaca ttgcaaacat tcccagcacg ttcaaacaca caaacagcta
     4441 tccaagcagg gttcttctct aacagaagtg tcttactagc tgtagttgta tgtagcgcgc
     4501 tttactgctt aacaatgatc ccaggactga aagaagtctt ctctatccca tcagcatttg
     4561 gattgacaga agtctttaca tgtatgggaa tcgcacttgt gacaattgtt ttgatggaaa
     4621 tcactaaatt gatcattgta cgagtacaag gaaataaata aaacgaatca acgaggttgt
     4681 gagcctgccg tttaattctg agtcacaagg tgcaatttca acaaacagct tctcatgttt
     4741 gttgaatatt gtgacttgtg accgaagagt tggcaggaga acaccgttta aggaagaagt
     4801 tgtaaaatca gcattttgag ctaatactga gggtcatctg attggacact gtttattcgg
     4861 aaagagggac tttgacacga ctttggtcac agtccctttt tttatttatg atagacggaa
     4921 agccaatcat tttattattc atcaaaagag atagaataga taaaagagga gaatgattta
     4981 ttccgaaaag tgaaaacata taacaaaaaa ttagaggaaa tcaaatgaat gaaaaagaat
     5041 gggatgaatt tgctgaagaa tattatgaaa tccagcaaga atcgcaagta actattgctg
     5101 aagatgtaaa aaattatctg aaaacggaga aagtcctgcc tgctgaaaca gcagcagacg
     5161 ttgctggagg atctggcaga tttctttcct tagcaaaaga aattaatcgc tatgatttga
     5221 tcgatttttc ttcaggaatg ctagaaaatg caaaaaaaga agcagaaaaa aatgagttgc
     5281 caaatgtttc ctttatcaaa cagtcgttag aagaatttat ccaatcaaat gagacatatg
     5341 aaatggtttt tacagcagca aatccagcat tggtacatct tattcaatta gaaaaattga
     5401 tgaaaaagtc aagcaaatgg tgcgtgataa tcagagtagt ggaatcaatc gatgatgttt
     5461 tttatcctat cgaaaagcaa ctaggaatga tagaagaaga tcctaataca tcgccagttg
     5521 taatggatca atttgaaaca tacttaattg atgaaggatt caaagtgaag aaaaaagatt
     5581 ttacttattt tacacaggaa tcaattactg aagaattgat gaagctatac tatgacgcgt
     5641 acgcaaaaga tcctgttgtg accaggtaca ttcgcaaact attcagtgaa aaacgagaaa
     5701 tccttagtac gactaagctg acctatagac tgctcctttg gtccgcagat aaaaaaagaa
     5761 cctttcacga ctcgtgaagg gttcttttta tgattttatt atattttgta gtaacgaata
     5821 tcattttcga tctttgtaat cgaaaaaggt acatctgaag tatattctgc acattctccg
     5881 tgttcaggaa gcgtctcact gaaaatcgtt tcatattcgt caacagtgat ccgtgttcga
     5941 gaatctagca tctcttgatg agattgtgcg aagagatatt cttgatagtt ttcttccaga
     6001 taacctgtaa aaaattcact tactgcacca gaaccgtagc tgaatagacc gatgcgatct
     6061 cctggctgta gtgatttcga attttccagt agagaagtta gccccaggta taatgaacca
     6121 gtgtaaagat taccgattcg tcggctgtaa cggatgcttt cttcatagcg agccataaga
     6181 cgttcctgat tttcttcgtc tgtttggtct aatacgcttt gcaatgcctt ttttcccatc
     6241 ttagtatacg gaatatggaa agcaatcgcc tgataatctt cgagtcctcg acccgacaat
     6301 tctttatgtc gattccaaac tttttggaat gattcgatat acgtagaatt agataaagga
     6361 ccatcaacaa caggaaattc gctataatct ggacgccaga aatcatagat atcttctgtc
     6421 agaaatacgc tgtcgtcttc aatcgataaa atacgcgggt tttgagtgat catcatcgca
     6481 acagcaccga caccttgcgt cacttcacca ccgcttgcca agctgtaacg agcaatatca
     6541 cttgctatga ctagtacttt tcgttctgga tgatttttga catattcttt cgccatgtgc
     6601 aaagctgcgg tgccaccgta gcaagcctct tttacttcaa aagaacgagc aaaagattgg
     6661 attttcagta aatggtggat aattaccgca ctcgcttttg aatgatcaat cccggattct
     6721 gttccgacga tgaccatgtc gattagctca cggtcttttt ctgttacgat tttgctggca
     6781 gcatttgctc ctagtgtaat gatgtcttca tttgcacgat tgactgccat ttggtcttga
     6841 ccaatcccta tatggtattt tgcaggatca tccccacggc tttctgccaa ctctgtcata
     6901 tctaaatata aattaggaat aaaaaaggaa agacgatcaa tccctatttt catttcaaca
     6961 cctctttact tatgataaaa aacttacttt actaaggtat cataaaaaga ttaaaagaaa
     7021 tataaaaaag agaatattta aggattgtta aaatttaatc ttagaaaaaa ataactggaa
     7081 caagagctat ttgtttttac agcaaagaat ggtatatttt tgtaggaggt ggcttacttg
     7141 aaagaagtcg ttatgataga tgctgcaaga acgccgatag gaaagtatcg cggaagttta
     7201 agtccattta ctgcagttga attaggcaca cttgtgacta aaggattatt agataaaaca
     7261 aaactgaaaa aagataaaat cgatcaagta atatttggaa atgtcctgca agctggtaat
     7321 ggtcaaaatg ttgccagaca gattgctttg aacagcggtc tccctgtaga tgtcccagca
     7381 atgacgatca atgaagtttg cggatctggt atgaaagcag tgatcttagc acgccagctg
     7441 atccaattag gtgaagcaga acttgtgata gccggcggaa cagagagtat gtctcaagca
     7501 cctatgctga aacagtatca gtcagaaaca aatgaatatg gtgaaccaat ttccagtatg
     7561 gtcaacgacg gattgactga cgcattttca aatgcacata tgggattaac cgcagagaat
     7621 gttgcaacac aattttctgt gagcagagaa gagcaggatc gctatgcctt gtcgtcccag
     7681 ttgaaagcag cacatgctgt cgaagccggt gtattttctg aggagatcat cccagtcaag
     7741 atttctgatg aagacgtgtt atctgaggat gaagcagttc gtggaaatag tacattggaa
     7801 aaactgggca cgttacgtac agtattctca gaagaaggaa ctgtaacagc aggaaatgct
     7861 tccccgttga atgacggtgc ctctgtggtg atccttgcat ccaaagaata cgcagaaaat
     7921 aataatctgc cttatttagc aaccatcaaa gaagtagcgg aggtcggtat tgacccaagt
     7981 atcatgggaa tcgctccaat caaagccatt caaaaattga cagatagatc aggaatgaat
     8041 ttatcaacaa tcgatctttt tgagatcaat gaagcatttg cagcttcttc tatcgtagtt
     8101 agccaagaac tgcagttaga tgaagaaaag gtcaatatat atggaggagc aatcgcatta
     8161 ggccatccaa ttggtgcaag cggtgcacgt atcttgacta cattagctta cggattgctt
     8221 cgtgaacaga agagatacgg tattgcttca ttatgtattg gtggaggttt aggcttggca
     8281 gtcttgttag aagcgaatat ggagcaaaca cataaggatg tgcaaaaaaa aaagttttat
     8341 cagcttacgc catctgaacg gcgcagtcaa ttaatagaaa aaaatgtatt gacacaagaa
     8401 actgcgttga tttttcagga acaaacactt tctgaagagc tctccgatca catgatcgaa
     8461 aaccaagtga gtgaagtgga aatcccaatg gggatcgcgc agaattttca aatcaatggc
     8521 aagaaaaaat ggattccgat ggcaacagag gaaccatctg tcattgcagc tgcaagtaat
     8581 ggtgcaaaaa tctgtggaaa tatctgcgca gaaacacctc agcggctgat gcgagggcaa
     8641 atcgttctat caggaaaatc ggagtatcaa gcagtgatca atgcagttaa tcatcgaaaa
     8701 gaagagctga ttctttgtgc aaatgaaagt tatccttcaa tcgtgaaacg cgggggcggt
     8761 gttcaagata tctctactcg ggaattcatg gggagtttcc atgcatactt atctattgat
     8821 tttttagtgg atgtaaaaga tgcaatgggc gctaacatga tcaactcgat tcttgagagt
     8881 gtggcaaaca agttacggga gtggttccct gaagaagaga ttctattcag tattttaagt
     8941 aattttgcta cagaatcatt ggcttctgcc tgttgtgaaa tcccattcga acgcttaggg
     9001 agaaacaaag aaatcggtga acaaattgcc aaaaaaatcc aacaggcagg ggaatatgcg
     9061 aagcttgacc cttaccgtgc agcaacgcac aacaaaggga tcatgaatgg tatagaagct
     9121 gtagtggcag ctacaggaaa tgatacacgt gcggttagcg cttcgatcca cgcctacgcg
     9181 gcaagaaatg gattatacca aggattaaca gactggcaga tcaaagggga taaactagtt
     9241 ggaaaactaa cggtgccttt ggctgttgcc acagtaggcg gagcttccaa tatcctgcca
     9301 aaagcaaaag catctttagc tatgttagat attgattcag ccaaggaact agcacaagta
     9361 attgctgcag tagggttagc tcaaaacctg gctgctttgc gtgcattagt tacagaagga
     9421 atccaaaaag gccacatggg acttcaagct cgttcattag cgatctcaat tggggctatt
     9481 ggtgaggaaa tcgagcaagt tgcgaaaaaa ttacgtgaag cagaaaagat gaaccagcag
     9541 acagctatac aaatattgga aaaaatccgg gaaaaataaa aaagcaatat ctttagaaga
     9601 ataaagcaag atttacagtt attttattta ctgcagatct tgcttttttg gctcttcgtc
     9661 aaattgtgtt ggcgaa
//
LOCUS       DBBGSP010000091         9321 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000091 DBBGSP010000000
VERSION     DBBGSP010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.091"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..106
                     /locus_tag="ACIZE9_002818"
     CDS             <1..106
                     /locus_tag="ACIZE9_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HGC6094625.1"
                     /translation="NESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(175..903)
                     /locus_tag="ACIZE9_002819"
     CDS             complement(175..903)
                     /locus_tag="ACIZE9_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HGC6094626.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(916..2196)
                     /locus_tag="ACIZE9_002820"
     CDS             complement(916..2196)
                     /locus_tag="ACIZE9_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HGC6094627.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(2337..2939)
                     /locus_tag="ACIZE9_002821"
     CDS             complement(2337..2939)
                     /locus_tag="ACIZE9_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HGC6094628.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            3184..3390
                     /locus_tag="ACIZE9_002822"
     CDS             3184..3390
                     /locus_tag="ACIZE9_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094629.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            3702..4421
                     /locus_tag="ACIZE9_002823"
     CDS             3702..4421
                     /locus_tag="ACIZE9_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HGC6094630.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4502..5185)
                     /locus_tag="ACIZE9_002824"
     CDS             complement(4502..5185)
                     /locus_tag="ACIZE9_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGC6094631.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            5404..7590
                     /locus_tag="ACIZE9_002825"
     CDS             5404..7590
                     /locus_tag="ACIZE9_002825"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HGC6094632.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            7936..8346
                     /locus_tag="ACIZE9_002826"
     CDS             7936..8346
                     /locus_tag="ACIZE9_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGC6094633.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            8360..8716
                     /locus_tag="ACIZE9_002827"
     CDS             8360..8716
                     /locus_tag="ACIZE9_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGC6094634.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT         3363 a         1526 c         1744 g         2688 t
ORIGIN      
        1 aaatgaaagt caagaagtat tgctgaaaga aatggagaat tggccaacat tttatccaga
       61 tacaatggat ggacgtgaaa ttgcacagga aatgcttttg cactgatagg caaaaaagaa
      121 ccgaagggtt tggatcggct ggtcatttag tcggtccaaa ctattcggtt ctttttatga
      181 aatcaatttc tttaatccac ggatagaggc tgggatggtc tcgccgtttg ccaacgtgac
      241 ttctctggtt tttttattaa tcgaccgcac attttgtgta ttgataacat aggatttatg
      301 acaacggata aaattccgat gcattttctc gatttctttg atcttctcat agaattgtaa
      361 ttgggcatga gtcaaatgga cttccagttt atgtggcgct cctagcgaag tagaaaaata
      421 ttggatgtct ttgatcggta aaaatttgat ctcatcatta aactctattt tgaagatatc
      481 tttttggatt tgggacattt gaaaatcttc gaaaattttg ctcaggatat gctcgacatt
      541 ttcttttaaa tcataaagat cttctttgac gatataatca gtcggttcga tgttgctttt
      601 taagattttc atcgacattt ccgtatggga agtcacatag attatttttc ctaaaggatc
      661 taattcacgg atcaatttac cgatcgctac accatccatt tcactgtctt ctagttcgat
      721 atctaaaaag taaataccaa aagaagaagt tctgatcttg gctgcattga gaagttcttc
      781 cggatcagag gtagaaatat ggacataact gtctaagttt tcaatcatga ttctattttt
      841 gatcaccgtt gataaaactt ctaattgttt tggatcgtct tcacaaatat aaatgggaat
      901 catatcatta ctcctttatt ttatttgtat ataaatcgtt tgagaaaaac gctggttttc
      961 aattgatgtt tcaaggaaaa gataaggatt ggtctttgtc aattcatcca agataaacaa
     1021 gccaaggcct tcgttttttg gatttgtttt tgttgagaac cctttttgtt tcaactggtt
     1081 taacggtaat gtatttgttg ttgtattgat cacacgaatc atcacggaat gattcttctt
     1141 gagtatggtc aattcgattt ttttcttctt tgcagcacta gctccttcaa tcgcattgtc
     1201 caagataata ccaagcatac gtacaaggtt taccgtatgt ttcgtatcca gttcgattgg
     1261 ctcaggaaaa tgaagctgga cgatcaaccc tttttcctgt gccatcatga gttttaatga
     1321 cagtaaacta cggatctcag gaactttcat attatccaac atacttagat tggccggaaa
     1381 aaggttcatc atctggcgtg taggtaatat cgtttgatca taataagacc gtaatccttc
     1441 taagtcgcct tctgaaatat agctgtgaag agaaaaaagc agattttggt aatcatgttt
     1501 gaattctctc aagtcttgat agtttttttc tagatctttg atataatcct gttgcatcct
     1561 gacttgttgc tctaataact gatcagctaa tttcttatta gagattttcc aataataaac
     1621 caagatgatc aggccaacac acagatatag aatgaaaaaa ctcgtattca aagctaagac
     1681 atcaggtgtt tcaccagaaa aacgggtata aaaaataatg atatagtatg taaataatat
     1741 caatgtcccg atcgtaccga tcatacggcg gtccacagtg tgaaaccaag tctctaacga
     1801 tttttttaaa caaaaagcta ataaagcaga taaaaaagcg gataagacaa tgtgaaaata
     1861 ctgcaatgaa tctcctggtt caataaccga agatttcaaa acaaaaaaat cgccgatgct
     1921 tgttaagtga tctcctaaaa gcgacgtcaa taacccaaaa ggaagcgcgt aaaccaattg
     1981 ttgacgcgaa gtcgaaaaga agaaaaaagt aagcatcagc attcctatag caattagagc
     2041 agtaaaaatc cctaaaatcg aatagaccca tccaatcaaa atacaagaaa tcagaatgac
     2101 tcccgcaaac agatatttgt atcggatgtg atggtcaatc aataagatac aaattgtgta
     2161 aatcaaatat tgcaacgcta tggaccataa aaacataaag tacagctccc attgattttt
     2221 accaaattat agcacaattg gcgtattatt tttttaattt ttcagggatt ttgaattcag
     2281 aactcatacc aaagcagcag ccagatacaa aaaagtcaga taagttagtt aattgtttaa
     2341 tgattgtttt tttcatgaaa gattcctcca aaattcatca agtagtttgt aataggaagc
     2401 aacgtagcta tttctaaaac aatcccaagt agcaaatagg tagaaaagta agaagctgag
     2461 aaaaataacg taatgagaga aaaaattaga aacatgctga tcgccttctt taataatggg
     2521 ggacgtttct cgggttcaat gggattgatt gctgtacctc ttgatccata gcgaagcagt
     2581 aacaaaaagc agctgattaa caaaaagacc atcattggga aggagatagt caattgcaga
     2641 tgtttcatca ccaagggaac gccccataaa taaagtagtg tccacagcag acaaacgaat
     2701 tcagagtcgg aatgcaatcc ataagcatat ctgcggatgc agatataaga aagaaaggtg
     2761 attcctgttt ccgcccatga gcctgtcacc agagaaaaga ctagaacgac cgctagtttt
     2821 ccaagattat tcaataaaac ttctaagaca aattttactt ggacatacac catatcttct
     2881 tccgatttgt ctccgctgaa taaggcttct aataatttgt tcacaacttt atctttcatc
     2941 tcatacgtac ctccaccaca aattttatgc taaaaaaaat aaaaaacgtc ttttgtttca
     3001 taaaaagtgg ttttgacatc aaaaccgtca tgatctccta aaaaaatctt cgttttccaa
     3061 gaaccttacc aaaaaaagtg acagttttga tacgaaaagt actttttatg acaagtttgt
     3121 gctttttcga gtgatttatg ttaaaaaatt actgacctta taaaaggtga tggagggatt
     3181 cttatggaaa atgaacaatt gtttgaagtc ggcgaaacat atgcatttaa atctgattta
     3241 tttgaatcac caataaaagg aaaaatagaa aaaatctatg aaaatagtgt gatgatacgt
     3301 gtcatgaaat gcgcagtaga agacaatgat accgctcata atctgcactg gcagttagtt
     3361 gtacgcaaat caagtacaat agaagaataa aaacagataa aatgttgaga gcataaagag
     3421 gttgtgagtc tcccgtttag ctctgagtta caaggaataa tgttaaaaaa cagcttttca
     3481 tgttttatga atattgcctt gtgaccgagg tgttggcagg agaatactgt ttatttgaaa
     3541 aaagggctgc gacaagactt ttgtcacagc ctttattttc atgaatagga gttacttttg
     3601 gctactttta gagaagtagc ttttaaggag cagataaagt caaggctttt atttctataa
     3661 atgaagtagt aaaatgaaga acagatttta ttacaggaag gatgccgata attgtgatca
     3721 ttgttgcagg aacgatcggt gcagggaaaa gcacactaac tgaaatgctt gcccaagatt
     3781 tagaaacaaa acctttttat gagaacgtgg aagataatga agtattgccg ctattttatt
     3841 ctaatccaga aaagtatact tttttattac agattttctt tttgaacaaa cgctttttgg
     3901 caatcaaaga tgctttcagc catgatgaca acgtactaga ccgctccatc tacgaagata
     3961 gtatgctgtt tcatttgaat gcagatttag ggcgtgtttc tgaagtagaa gtaaagcagt
     4021 atgaaggtct tttagaaacg atgctgaagg agttagaaga aatttcgcca caaaagaaac
     4081 cagatctact ggtttatatt cgtgtatcct ttgaaactat gttagcgaga atcaaaaaaa
     4141 gaggccggga atatgaacag ctagaacaag atcctgaact ctattcctac tataaagaac
     4201 tcaatcgacg atacgaagag tggtatgaac agtttgatat atgtcccaaa atagtgatcg
     4261 atggggacaa atatgatttc gtagccgatc cggcatgtgg agaacaaatc gtacaagaaa
     4321 tcaagatgcg ggcaaagaaa atgacagaag aggcagatgc ccagtcgatc cgctacacta
     4381 caaataaccc gaaagcaaag ggaatcttta caactaaata atataaaaac taagcaaatt
     4441 gctcactcgc agatatttct ctgtgagcag catcttgctt agtttttttg attcattgag
     4501 atcaaatagt gaaccgattc gtatgataaa attgccataa atgaaatgtc tgagtgaggg
     4561 ccatgatcaa aaataaaatg gaaacgatca aaatcgaatg ggcgccaaac agatgatgac
     4621 agaaaacaag gacaatagct cctgcgataa aggcaagaac gacacttaga tagtggaaaa
     4681 atcgatcaaa atctgctttt tctttagaaa tacaataatc atataagttc gttgctaccc
     4741 cttttaaatt tccagttgta aataaattag tgtaggcacg cccgttgatt ttatcaaaag
     4801 ctacccactg gatcgatgca gtaaaagcaa tcaaaatcgt tactaatgcg ggatgctcat
     4861 ggacgggtgt caaactaaca aagaaaaaaa tcactgcttc ataatataga acaaacaagc
     4921 gccagaaatg tttttctttt tttctaaaat aatcaattag atactttgtt agaagaatcc
     4981 ctaagaaaaa gaaaagggta gacaatactt ttttaccaac acttagccat tctccgtcaa
     5041 atgcttggat gatcgataga atgatattgc cagtttgagc agaggcaaaa gcaccatatt
     5101 ggatataagt ataactgtcc atggctcctc cgataaatgt cagcaaaagt cctattgtac
     5161 gcccctcgtg aaaggaagtc tgcatttttt tcatcacctt ttatgaatat ttttgtcttc
     5221 cttatcttag cataaacgat tgaaaaaaaa ggaaaaattt tcagaaaact aaaatcatat
     5281 cgcttcccat tttcattttt agaaaggtct gttagtataa agaaaaaata gacaacgaaa
     5341 ctttaaataa ccaacttgaa ataaacaaat tcaaagaaga aagatgggaa ggaaatcaat
     5401 cagttgaatg aaaaagaaat tctccgatta caaaaagaat tgaaacgctg ggagaacaag
     5461 tataaaaagc ttcaacaagt ctttcggcta caagaagaaa tcattgctac ctatgaagcg
     5521 gcttatggcg aagcacccgg acttattgag gaagaagtac aagtaaaaga aagtgaagga
     5581 aacagctctt tctttaaaat gatggagaaa cgttcctata atcgcttcaa tcaagaacaa
     5641 aaagcagcta tcacatatga tatgaagaaa catcttcgaa tcatagcagg agctgggagc
     5701 ggcaaaacgc aaacaatctg tgcaaaagct gtttatctga tgacgcaaaa acaagtagac
     5761 gaagaacgca tactaatgat cacttttaca aggaacgctg caaatgaact aaaaaaacga
     5821 gtagataatt tcagccagag aaaaaccgct gtccatatcg gaacattcca tagtatcttt
     5881 tttaggatat acaatgaaat ttgtcgaaaa tttcctgaag tagcaatgca aggaatacaa
     5941 ggagactttt caaaggatac tgcacaaaaa gtgaatgctg ttttgcaaca gctgatacgt
     6001 aaatataatc tttatatatt tgatcaatat ggagaaaaaa cgattgcttc tcggttagac
     6061 tattggcaga atatgaacct ttcagtagaa gaaatggttc agttagttaa agaaaaatat
     6121 gattccattg ataagaatgc acgacagccg atatcagaac gactgtatgg attgctcacg
     6181 gaactccaag aacaaaaaag aagccagcaa ttgctagagt tcaatgatgt actccaaaat
     6241 ctgaaaagcg ctttggagaa tgaggagatc cagcattata tcggccaaaa atatgattat
     6301 ctattcattg atgaatttca agatactaat ccacttcaat gggaaatcgt gaaacggatg
     6361 acaaaggaaa acaggatcaa gttgattgtt gttggagatg atgatcagag tatctatgga
     6421 ttcagaggat cagagccagc atacatcaag aactttgaaa aagaatatcc taccaaaact
     6481 cttttcttat taactaatta tcgttctcgg gcagctattg tccaaggagc aaatagattg
     6541 atcagctata ataaaaatga tcggatacca aaggcgatga ttccagcaca aaaagaagca
     6601 ggtgttatgg aagcctattt gttttctgat actaaagcag aaagtcagtg gctaatcaaa
     6661 caaattcaga catttattca aaaaaatggg aaatataagg aatcaatcat attataccga
     6721 tcagcttcac aaacgcagca gcttgtccaa tctctgctga aaacgaatat tccttttgta
     6781 ctggaagcag atagtccata tgaaggtatc tttggtatca agtctttcca acatttctat
     6841 caaaaaattg ttcattggca aacagcactg aatctgcaaa agaaaaatca ggcctaccag
     6901 caattgctcc ggcagctgat ggcagactgc tacctgaaaa aaagtgaatg cgatcaatac
     6961 ttttctccta aatatcaaaa tatagccgtt gcagattata ttttgtcgat aagccccaat
     7021 ttaaaatcga aatctgcaga aatccgagag tttgaggaag cgttgcgtaa aacagaccag
     7081 catcaagaaa tctattcgct tgttcaaagc tatcttcatc tgccacgtat agctaaggaa
     7141 atcgaccaga gtgatcaaga atggatacga gaagaagtaa agcagcatgc tactttcaga
     7201 agactccaag ccttatcgca agaaacccaa gcgacagcta aagaattaaa aacccgcttg
     7261 attgcttaca gacaaggaaa acttgatgca ctatgtatcc agagcattca caaaagtaaa
     7321 ggtcttagtt accgaaatgt ctttttgatt ggttgtaacg aaggaagttt gccttataac
     7381 ggagcgacag aaaagaaagt aatcgacttt aatgaaataa aagcagaacc agtaacgacg
     7441 atagaagaag aacgaagact attttatgtt gcgatgacta gagcaagaaa tcgtctgtat
     7501 ctatgtgtac ctcaaatgaa aaattcaaga aaattgaaag tatcgagatt tatcaaagaa
     7561 accgggagtc gtgtgaaaaa aggaaagtga tagaagagag ggtgtgacag aagtggtcag
     7621 tttcaagaaa gaagaaggaa tgtacgaaaa ttgcttctca aatttttgtg aaatttcagc
     7681 ttattttcga agaagctatt tctggaacac agtttattcg gaaaagggag gtgtgacaag
     7741 aattttgtca cacctccctt atttattttg aaaatgagaa tactattatc aaaatagaga
     7801 atatatagaa aaattctcat tattcaaacg taaataatca gttattttga ttttttttat
     7861 attttattag ctaataattg gtattttaaa agaaattact gtagaattgg attataatta
     7921 aaaaggagtg agaaaatgat aaaagtatat acttcgccta gctgtacttc ctgtagaaaa
     7981 gcaagagcat ggttgcaagc gaatcaactt gaatttgaag agaagaatat ttttgccgaa
     8041 ccgttaacag aaagtgagat caaaaagatc ttggcagcga ctgaaggagg agttcaagat
     8101 attatttcca ctcggtcgaa aatttacgaa aagctgggca tagattttaa cgaattaact
     8161 ttaaagcaaa tgatcgtctt attcaaagaa tatccttcat tattgagacg acctattttg
     8221 attgatgaaa aaagaatact aatcggattt aatgaagatg agatccggtc atttgtccct
     8281 cgtgaaattc gatgtgttgc cagaaatctg atctatttac aaaacaataa catcttaaat
     8341 tcatagggag ggagccttcg tggaagtgaa agtctatgga tcagcgcact gtgtaacaag
     8401 tctgaaggcg aaacaatggt tagaacacca tcaattgcct tatcaatttg ttgacttaga
     8461 agaacgcgat ttaagtacag aagaagcaga agaattatgc agttttgaag aagtgcaagc
     8521 agaacagcta tttgcgactt ggtctgaggc ttttcacaac attgcgattg acctttcctg
     8581 tgtaggaaaa aaacaactga tttttttatg cacacaacat accaatctcc tcagacgtcc
     8641 tttgattatt atcgatgaag ttctatttat tggatacaat gagcagttga tggaacagct
     8701 tatcttaaat aaatagactt taactgtttt aatcaagtca ctgagcattt catacagttg
     8761 taacagtcga acacttagca tcaagcgtgt tatgtgttct ttttttgact ttatttttct
     8821 actatagaga catgctcaat ttatgtggtc aaaattcaaa tctaggtggg gatatagagt
     8881 taaaaatata ttgacatgtg taaatttaca tgatatattc atttctgttg ttttaagtag
     8941 caaagcaata aaatagtatt ttaaaaaaca tataaaatag ttgttgacat gttagaaatg
     9001 acatgataag ataactgagt tgttaaaaaa gaaccacttg tgaagcttga ttctatcgaa
     9061 aaaaacttca aaaaagttct tgacaaataa caaatgataa gttatgataa atgagttgct
     9121 gtaagatttc gaaaaacgaa atcaaaaaaa cttttaaaaa agagttgaca attacttgtc
     9181 tctctgatat gatataaaag ttgctacggc agccaaaaac gaatcgggga acactcctga
     9241 tgaagtagac ctttgaaaac tgaacaaagt aagacaaacc aaatgtgtag ggcgtcttga
     9301 ttcaattcaa gacaacaaac a
//
LOCUS       DBBGSP010000092         8746 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000092 DBBGSP010000000
VERSION     DBBGSP010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.092"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(977..1150)
                     /locus_tag="ACIZE9_002828"
     CDS             complement(977..1150)
                     /locus_tag="ACIZE9_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094635.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHIFIFAYVLAMIA
                     FLSGGWLIIYLLS"
     gene            complement(1153..1551)
                     /locus_tag="ACIZE9_002829"
     CDS             complement(1153..1551)
                     /locus_tag="ACIZE9_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094636.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KIAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1767..2822
                     /locus_tag="ACIZE9_002830"
     CDS             1767..2822
                     /locus_tag="ACIZE9_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094637.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTANLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2842..3195
                     /locus_tag="ACIZE9_002831"
     CDS             2842..3195
                     /locus_tag="ACIZE9_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094638.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3377..3664)
                     /locus_tag="ACIZE9_002832"
     CDS             complement(3377..3664)
                     /locus_tag="ACIZE9_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094639.1"
                     /translation="MKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAKLKS
                     DSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3677..4495)
                     /locus_tag="ACIZE9_002833"
     CDS             complement(3677..4495)
                     /locus_tag="ACIZE9_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6094640.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAVNENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWMVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4721..4942
                     /gene="relB"
                     /locus_tag="ACIZE9_002834"
     CDS             4721..4942
                     /gene="relB"
                     /locus_tag="ACIZE9_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGC6094641.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKELMKEHEENDQSISHEDMLKELGL"
     gene            4944..5210
                     /locus_tag="ACIZE9_002835"
     CDS             4944..5210
                     /locus_tag="ACIZE9_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGC6094642.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            5377..5862
                     /locus_tag="ACIZE9_002836"
     CDS             5377..5862
                     /locus_tag="ACIZE9_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094643.1"
                     /translation="MGWYGAYSSANEVIEEKKGYAKNGLEIVDTKVTKTYGIILFKDA
                     EGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFFVGDQEKMVKQQLDRIKEE
                     NNKPNLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQDGSLTRFTRLSAGDVKEV
                     A"
     gene            6356..6640
                     /locus_tag="ACIZE9_002837"
     CDS             6356..6640
                     /locus_tag="ACIZE9_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094644.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGVVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKNSFIGKLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            6656..6793
                     /locus_tag="ACIZE9_002838"
     CDS             6656..6793
                     /locus_tag="ACIZE9_002838"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094645.1"
                     /translation="MEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTSLEC
                     V"
     gene            6914..7168
                     /locus_tag="ACIZE9_002839"
     CDS             6914..7168
                     /locus_tag="ACIZE9_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094646.1"
                     /translation="MNYTDEEQITLEYVFTNEKGEEIEKVLIISSKDLENALTYEPYE
                     STVTVNEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            7250..7435
                     /locus_tag="ACIZE9_002840"
     CDS             7250..7435
                     /locus_tag="ACIZE9_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGC6094647.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            7502..7897
                     /locus_tag="ACIZE9_002841"
     CDS             7502..7897
                     /locus_tag="ACIZE9_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGC6094648.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEDLLEK"
     gene            7914..8264
                     /locus_tag="ACIZE9_002842"
     CDS             7914..8264
                     /locus_tag="ACIZE9_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094649.1"
                     /translation="MKSTHLNYFSRTLINNLLKDTTGISVSTKHFANDLIIFEDNNLR
                     IEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKKAKLLFEFQT
                     DYHNELLAQSEILD"
     gene            8286..8660
                     /locus_tag="ACIZE9_002843"
     CDS             8286..8660
                     /locus_tag="ACIZE9_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094650.1"
                     /translation="MKQTQTETINDTLADQLAGYYKLFEMSKAQRLIHYLWKYKILFL
                     FWEATLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVISDAGIERN
                     IKRVSFKITLNKPTDKKLSEAF"
BASE COUNT         3064 a         1471 c         1368 g         2843 t
ORIGIN      
        1 acttttgttt cgtgttaagt ttctttacat tcctacgcac ctcgagtgta aaatttcttt
       61 attcctccca cgctccatgt tattttatat ttcctttttc atgttatttt tatccagaaa
      121 ccgatcaagt ttttacctat tcccaaaatc catttattcg ttattttttt cactgattaa
      181 gaataattat ttgatgctta aattagctaa aaaagcgatt tgttactgat ataatcatga
      241 tattgcagct gaattaggcg gaaagataaa atgttcgcaa aatcaaagta tcaattatct
      301 tgttttttta taaatttgta agtaaaaatc taaaaaagtt ttcttttaat tggtatatgt
      361 attaaaatca catttaatca cccataaagt atgcgctttc atttttttgg atgagattaa
      421 tatcaataaa taacgatgta aaaatcattt attatgctct tttataagga tattaattga
      481 tctaatttga aaaaaaatca aaatttaaat gttttaatat tacaaataaa atcatgttat
      541 tgtaaaatgg tataaaaaag ctaaatattc tatttttgtt attttattag caggaaaatt
      601 taaatagttt tacaagaatc cgtagaaata tattggtttt gccttcagat taatactgga
      661 tcatattaat ctgaatataa tatatgaact aataaatagc ttaacctcgc tattttgttt
      721 tttctgatca ctatctatac agcattagta aatagaattt taaaaataaa aaaattaaga
      781 caaaaaagta tcaacataaa catatacata tacacgttta tgttgattca cttaatttgt
      841 cctttaaaaa gcacttattt taatataatg ttattttata atcttattac aagctgattg
      901 ttaggcgttg tcctttcatt acatttatta acggttattt tattgtttaa tttattaatt
      961 atttttgatc taaaacttag cttaacaaat aaataattaa ccaaccgcca gataaaaatg
     1021 cgatcattgc taatacataa gcaaagataa aaatatgttc gatcagctta aaccctgatg
     1081 cgattaagca gaccaagtaa aatagaaatt ctcttacaga taatggtaat tttctaacta
     1141 gcatactcat aattaacacc ccaaagtaat attgtatttt gaacatttta catccaatac
     1201 agcatcaatc aaccattgcc aatcaaaaat acaaggcttc attgaagtat gtttttcaga
     1261 tgaaaagata taatataatt tcttcggaat aatattttca gttgttggga tcaagctaaa
     1321 tctaataccg tctaactcat agctaccagc tttctctcca ttaaaaattt ccttagcact
     1381 ttcttctaaa gaatcaaaat atttttcgac agcaatcttt gaagctttta ctattgaagc
     1441 atttcccttt tcgataaaat ctgcttttgt tttaccgaca ataagtaatt cttgatcagt
     1501 aaaatcttct aaaataatgg tagtgtaatt cttatttctt ctcaatcgca tcaggatcac
     1561 tccttaatat aatttatgtt tttataatat cataataaga taaatttgca agcatttatt
     1621 tacacctttt tatttacact ttattataat taattagact tttatgattg catttttttc
     1681 ttataaacag ttgcaactaa tagtaaatag gtgtaaacta ttttcgtacc gaaataccat
     1741 aaacacaaac agaaagaggt cataccatga aagaaccatt attgttttcc gttgacttag
     1801 ggaataaatc agtaaaagaa atgagtacac acgtttctcc actctcactt ccctctcgta
     1861 ttttgaacaa aaatatcatt aattcaggac gtttttctaa tataggttcc tcattaaaac
     1921 gatcactaaa cgtttctgaa tatagcctag taaacactac tgaaagctat tactttggga
     1981 aggatataca cgagctagga aaagatgact acgtgataga atcactaggt tttgggatca
     2041 gcagatacaa gcaggaaacc taccaaaata tcctatcttt ctctttagct aacctagcac
     2101 gtttagaaga tcaatctgat gacgttttaa ccgctaatct agttttaggt ctgccttcat
     2161 ccgactatac cgaaacaatc gtcaaatacg tgatgcaaca agccacacga caacattcag
     2221 ttgaagttga cggtaaagct tataatataa acgtagatac cgtttgggta ctgccacagc
     2281 cgattggaac actatataac ctcctacttg ctgatgatgg tagtgtacaa gatgaaacat
     2341 tgatcagtca gaagatcggt tttgttgata ttggcggtgg cacgaaactt tttgatgttg
     2401 tccaaaattt tgaaattgac gaaaacaatc gtgaacaaaa ggataccggc atttttactt
     2461 tatataatcg tatcgtaaat atgcttgacc ttccgatcag tcctaatgct ttccaacttg
     2521 aaaagattat ccgagaaggc aaagaaaaag gcgtatatct atttaagcca agcggaaatg
     2581 aaagttttga tatttcagaa gtagttgaaa gagaaataaa aacatacacc aatatggttg
     2641 ttgcagaagt tttagctaca ttcaaaaact tcacaacctt agataaagtt gtctttactg
     2701 gtggtggagc ttctattatc gacaaacaac ttgtaaaaga taaaattccg cataccttgt
     2761 ttgttgaaga cagtgaattt tctaatgtaa aaggctttta caagtttggt ttaactcaat
     2821 aaaacagcga aggagatcaa catgaataag ggaaaatcag agcgttatgt agttataatc
     2881 aatagagaaa aggttagcga gttaccttta gcagagtttc ttgaatccga atatgaaaca
     2941 ctaggcgtta aatactctca gacgatcaaa aaagctttga acctatatcg gcgtgtaaag
     3001 aacaatgaag ttacaattat tgaagcaggc aacgatagaa acgatagcaa agtagcagaa
     3061 gtaaagaata aaccaactga tcataaccct attcaacaag agcatccttc aacggttaca
     3121 tccgatcatt cagcaaagaa agaaaagcca atgctgaaag ggttcaatgc accaagtaac
     3181 aaagacttac tttaaaaata aaaaggcgag gttacaatac ctagcctttt tattatgtac
     3241 aaatataaac ataaacatat acgtatacat gtatataaac atgtatacgt atatatccat
     3301 aaacacgtat attaaattta gttaagctat acctaaccgc ttattccaat aaaaaaagtg
     3361 atcagcttta aactgatcac tcaccaaaaa cttcatcata caagttatct atcatttcac
     3421 caagtaaagc tgaatctgat cgaattccta acttttcgct gattttagat agtttctttc
     3481 tttgcgatgg ttgaagcgtg aattgataat ttttcttctt ttcagaacta tcacttttta
     3541 gtttagctac caaagaactt gttgtttctt taggtgtttg tttaggttct tcaactgctt
     3601 caaccacttc aggaacttct tctacttcag cttcagcgaa ttttttaaat ctattttctt
     3661 tcacttcaat cactccttat tcttgtgccg tatcaattat tttgttgtat agcgtaaacg
     3721 tgctttcaaa gaaatcctta ttcttacgat agatattctt atccttagcg aactcagcaa
     3781 tattcttacc ttctaagcta gttgcattaa gcaattcctt ctcttgtaca tatccaagat
     3841 aattagataa cgttggtacc agttctagga actcacgact tgaattagta ttatgtttga
     3901 tcctgctacc gatcgtagcg tatttagttt ccatcagtgt ttcaccagtc ttaatatcaa
     3961 tcaactgttt tgctagtgca tcaatatctt taccaagctt cagcaaagct tcaaaaccat
     4021 ctttagatgg atcagaaatg cctacgacaa gatcagatac agcccaagca ttttgagcta
     4081 gtagacctgc atcattatga gtatcaatca gaattagatc atacttctct ttaagctgtt
     4141 catagttaac aaccatccat ctaaacagta gggttctgtt gttaggcata tcacgcattt
     4201 gcatctcaac ttgttttaaa tcttcacctg ctactaaaat atccatgttc tcatttacag
     4261 ctaaaggttc agctgatcca tgaagatata aatgattgat tgtattctct cttttcgctt
     4321 tactgaaagc atcaggaaat cgttttgata ggttttgcga cttatcttca tcaatataca
     4381 gcaccttcat acctaaattt tcgacagcat atccacctag attgtagatt gttgttgttt
     4441 tacctgttcc acctttttca atgtttccag taatgattga caacttcttt tccatgatta
     4501 aacctccctt attaaccttt tgtaactcca ttatacacta taaacacgtt tatgtatatg
     4561 tttatataca taaacgtgtt tatatttata tttgctttta tattctacaa cataaacata
     4621 tatatgtata tgtttatgtt tatgtatata ttcatatata taactattgc atttgtcata
     4681 caatcgtagt acaatgtaat tgaaaaggag ttgataaact atgccagtaa taagtattcg
     4741 tgtatctaaa gaagaaaaag attttcttga aaaagttgct gaattcaacg gagataacat
     4801 ttctgaattt atgcgtagta attccctgca aacagcagaa acgttagtag actttgccac
     4861 ctacaaggaa ctaatgaaag agcatgagga aaacgatcaa agtatttccc acgaagatat
     4921 gctaaaagag ttaggcttat aagatgactt accaagtaag atatgaacgt gaagctcaaa
     4981 aagcgctaaa aaaaatggat aagtttcagg caaaggttat cctaaactgg atcgagaaaa
     5041 atcttgtagg cactgatgat ccaagaaaac atggtaaagg tctaacagct aataaatcag
     5101 gctactggcg atatagggta ggtgcctacc gtataatagc tgatattagc gagcatgaag
     5161 tgacaattct tatattgtct attggtcaca gaagtgaagt ttataagtaa cagacaagct
     5221 gataaggctt gtctgttttt ttgttaaccc aacaaaatca ctgtttacga tcccacttta
     5281 cctaaaaaag aacaataccc tcttgttatt atacacactg gtgtgtataa tataagtgta
     5341 aacaagctaa ttaactttca aaaggagcga ttttttatgg gatggtatgg tgcttattca
     5401 tcagcaaatg aagtgatcga agaaaagaaa gggtacgcca aaaatggttt ggaaatcgta
     5461 gataccaaag taacgaagac ctatggtatt atccttttca aagatgcaga aggaacctac
     5521 gatattgaca gcttcatctt tcgagatgaa atgtacaaac caatctactt cttaaatgac
     5581 agtcctgctt actttaagaa aattccgaaa aaatggttga aattctttgt cggtgatcaa
     5641 gaaaaaatgg ttaagcaaca actagataga attaaagaag aaaacaataa accaaacctt
     5701 gatgacttat tagttgcagg taaaacttac tcaatctggg atggatcgta tgtcgctgtt
     5761 tatcagtata aactcaaacg tagctttatt tttagactac aagatggatc actcactcgg
     5821 ttcactcgac tatcagcagg agatgttaag gaagtagcct aaaacttaaa tacataaaca
     5881 taaacgtgta tacgtttatg tttatgttta tgtatatgta tatgaatata aacgtattag
     5941 gtacgaacgt ttttaaatgc ttttctgggc tttgatttta gggtagggct aaaacatcca
     6001 ttgatccaaa acagctcaga aacgcattta aacgtatctg ataccaatat tacagaagga
     6061 gtgtatcgta tgattaacct atttctttta gtgacagcta gtacattatt ctttactgga
     6121 atatcactga taatttccta tttgatctat aagaaagccg aaacttacac aagcaaagca
     6181 accggactag ccgtttcctc ctttttaact ttgctgactt tttttgttac tctatcgttt
     6241 tcttttgttt agcacagctg atccatcagc aaaaaacctc tctttacatt atacacacta
     6301 gtgtgtataa tgtaattgta aacaagctaa ttaactttta ggaaggagtg acaatatgct
     6361 aacagctaca ttacagcaac ctactcacgt tgctattgca gaaagctata caattaatgc
     6421 aggggtcgtt aaacagctga tcaaggatcg agaattcaaa aagtttaaca gtcgtcaagc
     6481 gtataacaga cagttaaaga aagctattct aaagcacaaa aattccttca tagggaaatt
     6541 ggaaagtgtg gatgttaaaa ctgtttcaac ggcattttca gttgttgaag tgactattga
     6601 cggtcgcttg atttctctat ttgcttttgg aattaattga tagggagtgt ggactttgga
     6661 aggtaagact tttgcagaaa tttggactga atttattgag gtaccaactc gcattgatcc
     6721 gataacttct gaaaaggtat tggatgcaga cttctacaat ctcaaagcag gtactagcct
     6781 tgaatgcgtt tagatgtatt tagaagagca tttcaaaggc gtaacgctcg gtcacgtctt
     6841 ataccacaat ggtgccgagt gggatgcaat tggaaatatc catttttctt aatacaagaa
     6901 aggagaacac aatatgaatt ataccgatga agaacaaatc actttggaat acgttttcac
     6961 aaatgaaaaa ggggaggaaa ttgaaaaagt cttgatcatt tcatcaaaag acttggagaa
     7021 cgctttgact tatgaaccat acgaatcaac cgtaactgtc aatgaattct tagataccta
     7081 tacttctaat gatacttggg aaattatgaa tatttgcaac gctaataaca ttcaatttgc
     7141 tgaaaaaacc aataaatcat tttattagtt ttgcaataaa acatcctctt tttctattga
     7201 ttccatacac aacaatgtgt ataatagatt ttgtaaaggg agggtagcta tgcctaagac
     7261 agcaagagaa attgtaaaaa ttctcaaatc taacggcttc aaaaagactg gacaaactgg
     7321 cagtcatgca aaattttata attccaagac taaaagaacg gtcgttgttc cgatccacaa
     7381 tggtgatgta ccactaggaa cagaagctaa tatctggaag caagcagggc tttaacagcc
     7441 ttgccttcct atttggtatt aggcatacta tcctctctta cactagaaaa ggagcgagga
     7501 aatgaagaca aaaaatattt tttatccggc aatcttcgag aaagaaggag aagcttataa
     7561 catcgttttc cctgacttac cggaaatatc tacctttgga aatagtcttg aagaagcata
     7621 tttaaacgct aaggatgctt taggattagc gctatatagt gtaccagatg cagaatttcc
     7681 taaaccatca gcagtggaag aattaacttt gaaagccaat caagtagtag taatcatcca
     7741 actaaacatt aaacttttcc gaagaagctt aaatacaaaa acaattagaa aaaatgttag
     7801 tgttccggaa tggttagttc ttttagggaa ggagaaaaac ataaacttct ctcaattact
     7861 tcaaaaagca ctagaagaag atttgcttga aaagtaaaaa ggagaccgaa cctatgaaat
     7921 ctacacactt aaactatttc tctcgaacgt taatcaataa tctattaaaa gatacaactg
     7981 gcattagcgt tagtaccaaa cactttgcca atgatctaat tatttttgag gataataact
     8041 tgcgaattga gatgtttatt gaacaggcaa ctcctaactc aatacctgaa ttctgctata
     8101 cgcacactga aaaaatgaaa catgcaaaat cagttaaaga tgttgaagca ttaagtgaat
     8161 cactaacgaa cgctttaaac ctcgttaaga aggctaaatt gttatttgaa tttcaaaccg
     8221 actaccacaa tgagttgctt gctcaatctg aaattttaga ttaattgaaa caggagaaga
     8281 gaaaaatgaa acaaacacag acagaaacca ttaacgatac gcttgctgat caattagcag
     8341 gttattataa attatttgag atgagtaaag cacagcgctt gatccactat ctttggaaat
     8401 acaaaatttt gtttcttttt tgggaagcaa cactaacatt ctcagttctt ttttataagt
     8461 cagattttta taatcaacac ttagttttag ggagtttttt gcttatctac accattttga
     8521 tgcttaattt atatacctac atcacacttg aagaacactt agtaattagc gatgcaggga
     8581 tcgagagaaa catcaaaagg gtatctttca agatcacgtt aaacaagcct accgataaaa
     8641 agctctcaga agcgttctga gagcttttga cattttcttg tataatttat cctaacacat
     8701 tacaaagcac ctaattcgag cttatatcaa gcaaatttgc tattta
//
LOCUS       DBBGSP010000093         8675 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000093 DBBGSP010000000
VERSION     DBBGSP010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.093"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..1101
                     /locus_tag="ACIZE9_002844"
     CDS             <1..1101
                     /locus_tag="ACIZE9_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGC6094651.1"
                     /translation="KKETIVRFEQYNHMPLVTRLKKQRYTCKNCRTHWTAQSYFVRLS
                     HSIADHVRYKIASLLTEKVSLSFIAKSCQVSLTTVTRTLKEFKSYLPKPSKKILPRVL
                     MVDEFRSHASIEDKMSFICADGETGNLIAVLPTRKLPRLTSYFLGCTNPEEVEFLVTD
                     MNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQALNELRIREMNELRKAGQKSQAEKLKK
                     NWRFLLKNRASINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSAPLKEAYPFFHELV
                     EAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITSAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
     gene            complement(1280..1615)
                     /locus_tag="ACIZE9_002845"
     CDS             complement(1280..1615)
                     /locus_tag="ACIZE9_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGC6094652.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(1599..1862)
                     /locus_tag="ACIZE9_002846"
     CDS             complement(1599..1862)
                     /locus_tag="ACIZE9_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGC6094653.1"
                     /translation="MAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQGKI
                     PFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2322..3125)
                     /locus_tag="ACIZE9_002847"
     CDS             complement(2322..3125)
                     /locus_tag="ACIZE9_002847"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC6094654.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3103..4227)
                     /locus_tag="ACIZE9_002848"
     CDS             complement(3103..4227)
                     /locus_tag="ACIZE9_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6094655.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4243..5058)
                     /locus_tag="ACIZE9_002849"
     CDS             complement(4243..5058)
                     /locus_tag="ACIZE9_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6094656.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5048..5920)
                     /locus_tag="ACIZE9_002850"
     CDS             complement(5048..5920)
                     /locus_tag="ACIZE9_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013669610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC6094657.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(6005..7294)
                     /locus_tag="ACIZE9_002851"
     CDS             complement(6005..7294)
                     /locus_tag="ACIZE9_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC6094658.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7438..7950)
                     /locus_tag="ACIZE9_002852"
     CDS             complement(7438..7950)
                     /locus_tag="ACIZE9_002852"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094659.1"
                     /translation="MTINCDLKEEGLEMAVFSLAQTYQIWPQIVLSGYVQLSWAAIWG
                     KHIFYNIENQFEGKKLGDITEADLIDTLQKLAYQSVQIVNIHEGWLTKLAREVGQQLG
                     LTFSVWTVNELETIEYLARCGVYNITSRCAWAYLWKKGAQNKLFYNQNRGVKRFGDGI
                     HDHMGALFLA"
     gene            complement(8017..8160)
                     /locus_tag="ACIZE9_002853"
     CDS             complement(8017..8160)
                     /locus_tag="ACIZE9_002853"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HGC6094660.1"
                     /translation="MITAHSGSDNTEENSWAFLRFCLDRQLCFEVDVRQQTDGTLILA
                     HDR"
BASE COUNT         2691 a         1850 c         1371 g         2763 t
ORIGIN      
        1 aagaaggaaa cgattgtccg ttttgaacaa tacaatcata tgcctttggt tacgcgccta
       61 aaaaagcaac gctatacctg taaaaactgt cgtacccatt ggacggctca aagttatttt
      121 gtccgactca gccattcaat cgcagatcat gttcgatata aaattgcttc tttactgact
      181 gaaaaagtat ctttgtcttt tattgcgaaa agttgtcagg tatctttgac taccgttact
      241 cgtacattga aagagtttaa aagctattta ccaaagcctt ctaagaagat tctccccaga
      301 gtattgatgg ttgatgaatt tcgttcgcac gcttccatag aagataaaat gagctttatt
      361 tgcgcagatg gtgaaacagg aaacttaatt gctgtcttgc ctacgcgtaa attacctcga
      421 ttaacaagct atttcttagg ctgcaccaat ccagaagaag tagaattctt agtcacagac
      481 atgaacgccg cttacttcca gcttaccaaa cgtgttctgc caaatgcgaa agtagtgatt
      541 gatcggtttc atattgtcaa acacatgaat caggcactca atgagttgcg tatccgtgaa
      601 atgaatgagc ttcgtaaagc aggacagaaa agtcaggcag aaaaactgaa aaagaactgg
      661 cgctttctgc taaaaaatcg tgcaagcatc aaccattatg agtacaaaac atggaaaagt
      721 ttccgagcac caaaataccc atttctcact gaagcaatga tgattgatcg attgcttgag
      781 ttttctgcgc ctctaaagga ggcgtatccc ttttttcatg aattagtcga agcctttcga
      841 gacaaagacc ctgacttatt tttctcctta ttggcagaac ttcccgaaac gttagatgac
      901 ggctttcggg agaagcttca aaaccttctg acctatgaag aaggtatcac cagcgcaatg
      961 atctatcctt attccaatgg aaaaattgaa gcgaagaata cccacataaa gacaatgaaa
     1021 cgagtatcct acggatttaa atcattcgag aacatgagaa ttagaatctt tttgatcaat
     1081 caattaatca atgtaagata acaaaaaatc tgaaccagaa tgtggttcat tctgacccgg
     1141 atttgatttt gcacaactca tcagtcctta ttgacaaaga gccaaaaatc tgagccagaa
     1201 tgaggttcat tctgacccag atttgatttt gtacaaccca tcagtcctta ttgacaaaga
     1261 gcccttcttt ttagtattat tataattctt ccatgcgttc ttccagtcgc tgtaaatcgc
     1321 ttggacttaa ttccccaatt tttttccatt tgaccttttt gttgtttttg ggtaattcgt
     1381 ttagagttcc tacgtcaatc caagattctt tttttagtcc tgcctgtttc caatccctta
     1441 tttcaacgta tttcagcttt attttatcgg atttagtatg atattttgaa gtaattgaca
     1501 gaaacgaaat tgtgtccagt ccatttttta gaatatagac aggccggcgt ttaccgccct
     1561 ctgcagctgt gaaagcaacg tagacggttg ctatatcatt agtattcatc ttcattgaac
     1621 cattcttcaa ttttttcgtc agtgtctagt ttttggacag gcaatttttc cgctaatctt
     1681 tgaatattat ggattcgttt acttttttcc gacaattcaa tagaaaatgg gatttttcct
     1741 tgctcaacaa tttgcttata aaaaacggtg acggctgttt tggggctcat gcctagttca
     1801 tcaataatgc tttctgcttc atttttcaat ttttcgtcca tagaaatttg taacttagcc
     1861 attttctcca cctctttctg acaaacacat tatatcacgg aaagagttca aatggaatta
     1921 atacaactac ttttgaactc cttgaaatgc agtgtattta tctaaatata aggaaaggat
     1981 atagtgctaa atggccttga tagatagaaa agtttcaaaa tccgccacag cgataattga
     2041 agcgaacact caacgacaca cagaacagga aaagactcct aaaagaacca aattaactag
     2101 gacgtgtctg aaaactccac aaagatgtgg tatgctctgg taaaaaacga atggcacaac
     2161 cacgaagacc gatatggttc ttggaaaact ttctccaccc tttttgtaat tggagggata
     2221 gtggtttatt gatagcgatt ttccaagttc ttcaagtgga accagacatt gagcaccacg
     2281 gctaaaaagt gaatgaagtc tttattttta atcaataatt tttaatgatt accagtaatt
     2341 ggttttttca tgcgccctat ttctatttga tgtggagtta aataatgctg ataagtaaaa
     2401 atttttccgt caattaaact gccactagtg aatcctgttc tattggtaaa aagagaatag
     2461 tctgggtatt catctacacc aaatgataaa gattcagcca taaactgttt tttaccagca
     2521 aattcagcac tgctaccttg atggatatgt cctacaaaaa tacctaaaat atcactttcg
     2581 gcaatcaatt cagcaaaacc ttccggaact tcagttacaa tagatggatc ttcccacgac
     2641 aatggatgat gaaccaataa aatcgttccc ttttcagcag gtgtacccaa ccactcttgt
     2701 aattgaatca tctgtcctat cgatattttt ccttcgtgct gggtatcttg agcagaatcc
     2761 aaggaaataa ttcgtaaccc attttgattc gtacaatgga tatactctcc cgtttcattg
     2821 ctttcaacac tcattccttc aaagaaaaca ctgcgacgat catgattccc acgacaaaaa
     2881 tagtaaggtg tggttgggaa atattgatcc aacattttcc gtaagacttg ataatcagaa
     2941 atcccccctt catgtactaa atcacctgtt aatagaataa aatcgtacac tgttaacgag
     3001 agttcttgta acaatttttc caatgccaac tgtggatttt taattgttgg aaatagttca
     3061 gcagtaaaca agttagtttg atagttttct ctaaaatgga tatcagagag atgcaaaaag
     3121 cgcatggcta ttccctcttt cttcaataaa ataatcagga tatcctaaat tttcttgcgt
     3181 ctgataatca aaaaaatgca ttctttcagg ttctatgcgg agattgactg catcaccaat
     3241 ctgccaagta ggtttttcat taaggacaat catttctata ccatcgactt taacggtgta
     3301 cgcataactt tgacctaata gctcacgata cttcacttga ccgtgtaaat cgcttgtttc
     3361 ttttgaaaag gttacgtgtt ctggtcttat gcctaaatac aatgagccac taacctgaag
     3421 aagttgtttt tgccaagctg gattcaatgt taaaaattga ctggctacct ttaatgttcc
     3481 ttgatcataa gtaactggca taatattcat gcctggcgaa ccaataaaat ttgcagtaaa
     3541 agtattttta ggtttcgtat aaacattttt cggcgtatca atcatctgaa ttctaccttc
     3601 attcaataaa acaatccggt cagctaacgt catcgcttca atttgatcat gagtgacgta
     3661 gacaaaagtt tgtttataac gttgatgaat ttttaccaat tcttttcgtg catccaatcg
     3721 taaacgcaca tccaaatttg ataacggttc atctaataaa aaataattac tccgtttaac
     3781 caccgcacga gccaatgcta cacgctgccg ttgccctcct gacaaatctt taggaagtcg
     3841 atcttggtat ggcgttaaac ctaacatctt caaagcttct tccaaacggt gctgaatgtc
     3901 agctgtctta attttattcg cccttaatgc aaaaataata ttctccttta cagtcatgtg
     3961 aggatataaa gcataatttt gaaaaaccat tgcgatctct cgttctccac aaggtagctt
     4021 atttgctagt tgtgtaccta aaaaaagctc tccactcgta attttttcca aaccagcaat
     4081 cattctcagc aaagtagatt ttcctgaacc agatggtccc agtaacacaa ttcgttctcc
     4141 agcggccaca gctaaatcaa tttcttttaa aatggtatgt tctccatatt tttttccgat
     4201 atttcttaat tcaagcgttt ctcccatgat ttgtcctcca atttatttaa tacctgcaga
     4261 aacaaaagtc ccgataatat atttttgaaa aattgcatac aagactaacg gtacaaacat
     4321 tgtaattaaa ctaatcgcca ttgctacggt aaaatttgtc ccaccttcag aactaatata
     4381 ggtctgcatc gccaacggca aagtataatt atctactgtc cgtaaaatta ataccggcca
     4441 aacatactca ttccaagagg taataaaaaa ccaaataccg gtagaagtaa tcgcatgtct
     4501 agtaagagga aaaacaattt tactcatgac ggttgtttgt ttgatgttat ccaatgccgc
     4561 cacatctaga aggctcactg gaatttcccg cattgtttgc gtcaataaaa aaatgcccat
     4621 cgcatcagca aattgtggta ttatcacacc ccaagtagta tcaattaaat taagttttgc
     4681 aatcaacaaa taattaggaa tcatcgcaac agtaaaagga atgaacatcg taccaatgat
     4741 gataaagtac cagattttct tccctttgat tcggcaataa gtaaaactat atgccgcaaa
     4801 aaaagctacg cctaacttaa caaccgttat aattgtagca ataaaaaaag tatttctcgt
     4861 aattttgata attggaagat tttcgaacaa atagcaaaaa ttttccaagg taaacggctg
     4921 tggtatcaaa ctagtaatcg tctgataggc atctttcaat ggcttaaaag aattggccat
     4981 aataaacaat aatggataga taataatgat tatgatgaac ataaataaga gatgtggcaa
     5041 ccagcgttta attttcatag taaaccccct tttccacaaa tttaaatatt acccctaaga
     5101 aaacagcaaa tattaataaa gttaaaactg aaattgctga agattctccg actttataca
     5161 tttcaaaagc cttttgataa gcataataga tcacgtttgc actaccatta ttcggtccac
     5221 cacgagtgat gatcttaatc ggagtaaaca catactgcag accttgaaca atggtcatca
     5281 ccaataaata tagtcctgtc gaactactca taggcaacac aattgtaaaa aaaatgcgcc
     5341 agatgggtac acgatccaac ttagctgctt cgatcatctc ttgatcaatt cccacaattg
     5401 ctgcaaaaat gacaatgaaa ttataaccaa aaactttcca agcagtaata cctgcaatca
     5461 cagcaattac ccaaccttgt aaattcatcc acataggcag tcttaaacca aaatttccca
     5521 acaagacagc aattggtccc gataccggat ttaatatcca tgtaaaaacc atccccgcca
     5581 ctaccaaaga aatcacagct ggaataaaaa ataatggttt atacaaattc tgcccttttt
     5641 ctataactat tcctaataaa aaggatgtaa tatatgggaa cacacagctc agcaagacaa
     5701 atagaacggt ataggacaaa gtattcttca acactttatg aaagactgga tcagtcagca
     5761 cctttacata gttggcaaag ccaacaaatt ctttagtggg ggccaccata ttccagtcaa
     5821 aaaaactcaa atagatcgta taaatcaatg gataaaaaac aaacacgccc aacaaaataa
     5881 ttgctggcgc cagatacaaa taacctacat agcgcttcat ttccgacagc ctcctcatcc
     5941 ttatgtcaaa agcagacgac cttgtttttc ctttcttaca ggcgctgtcg tctgcttgct
     6001 ttgcttattt gagtaactca ttaatttcct tttgagtagc tttcatcgtt tcattgacgg
     6061 aattacctga taaaatttta tcccgcatat ccaacaattt ttgttcagct tctaatccag
     6121 catctccagg aaatgaactc caactgacca tcttatccat ctgatcaatt gctggtatca
     6181 tcatctgatt ttcagctaag aaagctttta atccattttg ggcgtctgca acatctttac
     6241 gtggtggtaa ataaccagta ccttctgtcc atttagctaa agattcaaca ctataaagat
     6301 attttaagaa atcccaagtt gcttcctttt tcttatccgt ttgtgatgta acagctaaca
     6361 ttgcgccacc agcaggtagt ttaacttttt tcccttccca acttggtgac tcaactgctt
     6421 tagcagtaaa agtactattt ttttgaatgt tgtccctttg agcaatagtg gtatagacca
     6481 tcgcgacgtt accatcaata aagctttgca caccttgttc ccacgtagtg tgtaatgccg
     6541 tctggtcttt taccatcctt tgatataatt cataagcagc gataccatct ttagaagcaa
     6601 aggtagcttt gccatctttt attacacttg ccccattact ttctaaaatt gcttgttgtg
     6661 cccaattatc agcaggttct tgaatataca cgccatactt tccagttttt tcttttatta
     6721 tcttagaaaa agtttgaact tcttcccaag tttttggacc attttcatcc aagcccgctg
     6781 cttttaatat atcttgattt aaatataaaa ccggattact aatggagtaa ggaataccca
     6841 cttgtttacc atctttttca gacagtgcca tgatattgtc taaaaaatga tctttaaaat
     6901 aatcagcatt atccggatcc acttcttcta ctaaagattg aggattagta tatttgaaat
     6961 tttctgcaaa ataatcttta aaagcccatc ccacttgtac tacgtccggt atttctttgg
     7021 aggcaacaga agcttgtaaa ttttgcatca agcctttata catatcagga ttatattttg
     7081 ctacaacctt cactttgtct tgagattgat tgtatttatc tactaattca ttcactgttt
     7141 ttccacctag ggtatccgca ttaacatgcc aatactctat cgttacacga ccctccgatt
     7201 tttttgttgt cttggtattc ccactaccac aagctgccaa agagatgaca cttaaaacag
     7261 acacaacccc tataacaaga tttttcttta acataacatt aacttcctcc taatttcttt
     7321 atggccattt ttctaatcaa gaaatattat gaactaccaa tgtaaatttc tagttaattt
     7381 tctgtaaata attcgaaatt tgtgcatttc ggggtacagg gtcactggac atatccatca
     7441 agctaagaat aaagccccca tatggtcatg tatcccatct ccaaatctct taactcctct
     7501 gttttgatta taaaatagtt tattctgtgc tcctttcttc cataaatagg cccatgcaca
     7561 acgtgaggtt atattataaa caccacagcg cgcaaggtac tcaatcgttt ctagttcatt
     7621 gactgtccat acagaaaatg tcaatcctag ctgctgcccc acttcacggg ccaacttagt
     7681 taaccatcct tcatgaatat tgacgatttg aacgctttga taggctaatt tctgtaaggt
     7741 atcgatcaaa tctgcttcgg taatatcccc aagttttttc ccttcgaact gattttcaat
     7801 attataaaat atatgctttc cccaaatcgc agcccaagat aattgtacat agccactaag
     7861 aacaatttgt ggccagattt gataggtttg tgccagcgaa aaaacggcca tttccaatcc
     7921 ctcttctttt aaatcacagt taatggtcat ggttgccttc tcattggcca ctgcttgaaa
     7981 cacctgctca agggttaccg aatctgggac aacttcttac ctgtcatggg ctagtattag
     8041 cgtaccatct gtttgctgac gcacatctac ttcaaaacaa agctggcgat ccaaacaaaa
     8101 gcgaagaaat gcccagctat tctcctccgt attgtcacta ccagagtgtg cagtgatcat
     8161 ggtcattttg acccctcctt taattccgtg attttctccc acacgtccac tataccgatg
     8221 aagcgttaat ttcttgttaa tttcttgtaa attccctgcg ttttttcagt aaactagttg
     8281 taaatcttgc atgctccttc ctacgaactc atgaatcgtc gattttgccc ttctagctag
     8341 tttcaccaat taagtagttc tacattcccc gcttttaacc tactacacct ttttttgttt
     8401 tcagctattc cttcttcttg ctgaaagtcc ttgaggttct ttcttacagg ataccatcaa
     8461 ggtgttcaat ggcttattcc cattgaatga ccgagactta ctatcagatt tctgctcgtt
     8521 gaaccaagtc tttgatacag gatttcttcc gtcatcttct cacaaatacc accttgcgtt
     8581 tctctagcga ttggtcgatg tgcaccctcc cagtggactg tcactacccc tttttgctat
     8641 gcctagccca caaaaaaagc tgtcctcaca gacag
//
LOCUS       DBBGSP010000094         8668 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000094 DBBGSP010000000
VERSION     DBBGSP010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8668
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.094"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(151..1104)
                     /gene="menA"
                     /locus_tag="ACIZE9_002854"
     CDS             complement(151..1104)
                     /gene="menA"
                     /locus_tag="ACIZE9_002854"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HGC6094661.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1117..2220)
                     /locus_tag="ACIZE9_002855"
     CDS             complement(1117..2220)
                     /locus_tag="ACIZE9_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGC6094662.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2310..3245)
                     /gene="pplA"
                     /locus_tag="ACIZE9_002856"
     CDS             complement(2310..3245)
                     /gene="pplA"
                     /locus_tag="ACIZE9_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HGC6094663.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3547..5481
                     /locus_tag="ACIZE9_002857"
     CDS             3547..5481
                     /locus_tag="ACIZE9_002857"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGC6094664.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5938..6354
                     /locus_tag="ACIZE9_002858"
     CDS             5938..6354
                     /locus_tag="ACIZE9_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HGC6094665.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6368..6934
                     /locus_tag="ACIZE9_002859"
     CDS             6368..6934
                     /locus_tag="ACIZE9_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HGC6094666.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6957..7943
                     /locus_tag="ACIZE9_002860"
     CDS             6957..7943
                     /locus_tag="ACIZE9_002860"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGC6094667.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8098..>8668)
                     /gene="scm"
                     /locus_tag="ACIZE9_002861"
     CDS             complement(8098..>8668)
                     /gene="scm"
                     /locus_tag="ACIZE9_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HGC6094668.1"
                     /translation="SDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDT
                     STTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDS
                     STSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQ
                     SNNWITLAGVILLVIGLRITFMSYKKSKR"
BASE COUNT         2538 a         1674 c         1766 g         2690 t
ORIGIN      
        1 cgactttttc acaacctcct gataaacggt gttcaaaagc ttgcatctgc ggtaataagc
       61 ccaaccaaac gaaaaatata aggagctatt tttatttggc tgttcttatt acttgatgca
      121 gggcagtttt ttcacaacct cttcatgctg ttaaatggct tgcataatga ttgttagtaa
      181 tagccccaat acataactgg cattgaataa gaccatattt ttgatggaat agctgaaact
      241 gataggctgg ggtaacgttt gcttgaattg atccaaatgc ttcttcacaa ttggcaaggt
      301 caagaaggtg accaagatcg gccattcata gataccgctc aacaacccca ttaaaatcac
      361 gaaatagcaa gcatacatca atagctggaa taagactgtt cccgcaggac gtccgatata
      421 aaaaactagt gtatagcgat gattttcaat atcacggtca agatcccgca aattattagc
      481 caacatgata ttggcaatcg taaacaccaa gggtaaggaa gctaatacga ttgctgctat
      541 agcccaaaga tttcctacca aagcaaattg tccagatgaa aagttgactg tcagatcata
      601 gacatctgaa ccgaatgtat tgacataaac gaccatggca aaaattccaa ggcccatagt
      661 caccccactg aaaatttccc ctaaaggcat tcgagataaa ggaatcggtc cgaatgtata
      721 gaatactcca ataaaacaac agataaatcc catcaaaagt aaaagccaac ccgtattgat
      781 cgttagaata acgccgataa caaaaacaaa tgcaatcata gctaaaatca tgtttcgaat
      841 caatacagga gatagatttc tgcggccaat gacattttct tcatacttat atacttcaga
      901 atgagccttt tcataatcca tgtaattatt gatagcggta gtcgctaaat caaaaactag
      961 cattccaata aaaaataaaa aagtgtttag ccaatgtatc tcatgaaaaa aagcgataga
     1021 gaataatacc cctaccgcaa aaggaaatac actagccacc tttgttcgta tttcaactac
     1081 ttctaaaaag atttttagtg tcatggttcg tactccttat tttagttcag aacggtcacc
     1141 catcgtgtaa tgggagtcct ccgataattt gaaggtgtct ttgattggat cggtcacata
     1201 tactttatcg tcttttgtca cgaagatcgc ttccgtcccg ttattcaatt cgctttcgac
     1261 gtattccagt ccttttttca cacccattga aaagactgct gtagacaacc cgtcaccatc
     1321 aattgattta tctgttatga tcgtgacact tgcgatatca ttgtcgaacg gataacccgt
     1381 ttttggatca aacaaatgat ggtatttttt gccatctact tctaaataac gctcgtaaat
     1441 tccagaggta actaatgttt tgttccgttc tttaatagaa cctaaaacag atccgcgagc
     1501 catgttcgga tcttggatgc cgactgtcca gtcttggttt tcgcctcttg ggctgtggcc
     1561 taagacatag acattaccgc ccaagtcaac gatggcagtg gtcactcctt gttttttcaa
     1621 gactttcact acttcgtccg taatgtaacc tttggcgatt gcacctaaat cgatgatcat
     1681 tcctttttct tttagataaa cagttttttc tttgtcattt agttcgatct tatgataatc
     1741 cactaatttc aatgcctgat cgatttcttc ttgggaaggt tttctggcgt catcaaaacc
     1801 gattcgccat aattgtgtga ttgcaccaat cgccatatcg aatccgcctt gagaatcttg
     1861 gctatattcg taggcccgct tgactaacgt gtagacgtca tcagaaactt ttactggttt
     1921 gatcccagct tgctcattca cttcatcgat ctcagaacct ttttgattga tcgtgatttt
     1981 atcaccaagt tcttttactc gatcgaaggc aggtttcaat gctgattctt tgccttcatc
     2041 atacacacgg atacgaacgt aagtccctaa caagaactgt tcatcagaat atggatcttt
     2101 caatatcttg gtagctgctg aactttcagt ggttgtttta tttgctgagt tgctgcagcc
     2161 agttagcacc ataaaagaga tgcccagtgt gattaaggaa aatagtagtt ttttccgcat
     2221 ctttttcctc tcttcatttt gaaaggtgag acgactgcct aatctggcta tcgtcccacc
     2281 ctccaacttt tattagtatg attatgtgat tatttttctg ttacgatatt atctacttcg
     2341 attgtttgag tgtcgccttt ttcagctgca ttcactaatt gttgtgcgta catgatgaat
     2401 gaatgtgagc tgtgtgtagc acctgtaaca acttctacat tagcaggtga gccatcttct
     2461 tcgcccattg ctttgacgaa ttcgtcgttc agagtaggga tgtaagtttt tggttctgta
     2521 ccgctttttg ctttcatatt ttcattatat tctgtatcat cttgttttga tttaccgtct
     2581 ttgtcgatat aatcaaagtt tgattcagtt actttgccgc cagcaactgt catttcgaat
     2641 tgcacacggt agccgttaga gtagttcttt tcttcaagct tgtaagtgcc gtctttcaaa
     2701 tcagcaccat tgtcgatttc gattgtatct gtgttaccag cttgagcagc ttggatcaat
     2761 tgttgtgcgt agttttggaa gctttcagat gagtgagtag ctccagttac gacttccaca
     2821 ccgcttgcgc tttgtgcttt taagaattgg tcattcaact caggaatgta tttttctggg
     2881 tttgtgccag attttgcttc catgtttttg ttgtattctg catcttttgt ttttgattcg
     2941 ccgttttcat tgacgttatc atattttgat tcagtgattt tgccgtcttt tacaaccatt
     3001 tcaaagactg cacggtaacc atttgaataa tttttttctt ctaatttata tgtgccgtct
     3061 tgcaaatctc cgccagctac aacttttgca gatgattctg ttgtgctttt tgcagtcgaa
     3121 gattgtgctg tagatgattc agaagaagag tttgagcttc cgttgtcatc tgcgccgcaa
     3181 gcgcctaaca ctagagctga aaatgctaat acggcaaatc cagttacaaa acgttttttc
     3241 ttcattttaa taccccacca ttccatttct agtccacaat ttttctttgt gattcattat
     3301 acattctaat ctttttagcc tataagtcaa ctatttttga taaataaccc atgtaatatt
     3361 tcaaacgttt tctttcagca aatttcgtga aaaaacgctt tattttaaaa tttgaaaaaa
     3421 atccaaaagg agttagacaa aagaacagaa catctatata atatatggag attgtgtaat
     3481 aagtatcaaa ctaaaagaat tatcatatat tcattatata gatagtctat aaggagcgga
     3541 tgatcaatgg caaagcaaaa tattgtcgtt gtaggagcag gatatgccgg tgtttcagct
     3601 acaaaatact tggcaaagaa actgaaaaaa gaagatgtag caattactct gatcgatcgt
     3661 cattcgtacc atactatgat gaccgagttg catgaagtag ctggcggacg tgtagaacca
     3721 gaagcaatcc aatacgatct gcagcatttg tttgctcgtc aaaagaatgt acaacttgtc
     3781 acagacactg taatcggtat cgataaagaa cgaaaaatcg tcaagaccaa attaggttcc
     3841 tatccttttg atcagctgat ccttggaatg ggcggagagc cgaatgactt tggtacacct
     3901 ggtgtcaaag cacacggatt caccctttgg tcatttgaag attctgtaag gattcgggaa
     3961 catattgaga agacagtagc aaaagctgca ttggaaccag atgatgaact gcgtaaagcc
     4021 atgctgactt tcgttgtctg tggttctgga tttaccggta ttgaaatgat tggggaactg
     4081 atcgactgga aaaatcgcct agccaaagat tataaattag atccaaacga aatcacactg
     4141 atggtcgtag aggcaatgcc gacgatcttg aatatgttgg atcgaaatga tgctgcaaaa
     4201 gctgaacgct atttgcgtaa gcacaacgtg gaattattat tgaatgcacc aatcgtagaa
     4261 gtggctgctg atcatatcaa attgaaagac ggacgcaaca ttccgactca cacactgatt
     4321 tggacagctg gtgtcaaagg aacttctgac gctgctgact ttggattaga atcagcacgc
     4381 ggacagcggt tgatcgccaa tgaatatatg caggcaaaag gctacgaaga taaaaacatc
     4441 tatatcattg gtgatttagt cttttatgaa gaattcccag gaacaccgac accgcagatc
     4501 gttcaagctg ctgaacaaac aggacacaca gccgcagcga atatcgtggc ttcgatcaaa
     4561 ggcggagaaa agcataaatt taaaggaaac tatcaaggat ttatggtttc tattggtgcc
     4621 aaatgggggg tagctaacct atttgataag atccatttaa gcggattttt agctatcgta
     4681 atgaaacata tcgtgaattt gaaatacttc tttgatattc gttctggtta ttatatgttc
     4741 caatatttaa tgcatgagtt tttccatatc aaagatgatc gcaacgtgac tcgaggacat
     4801 tcttctcgtt acggcaatgt cttatggagt gtgccacttc gtattttcta tggtttagtt
     4861 tggttcgttg aagcttccaa aaaaatcatt gggaatggtg aagtgttcaa accaagtact
     4921 tggtttggtg aaggatcatg gttcactgga aacagtgtgt tcccttggac atgggaatac
     4981 aatgtaacag atgttgccag tggtgcttct gctgctggtg atgcaaccac agctgccagc
     5041 ggagcagggg caagtgccgg agaagcagcg actcaagctg cacattttgg tttgagttat
     5101 gcatacggtg aagaaccaat ggctgtgatt gagaagtcac cagactggtt cacaaagatc
     5161 atgcaagtga tcatgccaaa caatgatgta gcaatgttct tccaaaaatt catggtattc
     5221 tttgaaattg ccttggcatt agcattgatt gctggattat tcacatggct atgcagtgcg
     5281 acaacgattg tattggtgat cacgttctgc ttatcaggca tgttttactg ggtaaacatt
     5341 tggttcattt ttgttgcttt cgcattgatg aacggttccg gacgtgcgat tgggttggat
     5401 cgctgggtaa ttccatggct acaacgtaca ctaggtaatt ggtggtacgg tagaccaagt
     5461 tcccagtacg gcaagaaata aatagataaa gaacgttatt tgaatgcaag atttcaatag
     5521 aaaggggctg agacaaaccg tcacagcctc ctttttatgt aaaattaaag gaataagatg
     5581 cccgagataa gcctccatga gcaagacaca ggtgtcacaa cctctgttac aacctcttgt
     5641 tataaacggt gttccagaag tagcttcttc gaaaaataag ccgaaatttc acaaaaactt
     5701 gaaaagtaat tttcgtaaat tccttcttat ttcttgaagt tgcccacttc tgtcacaacc
     5761 tcttgttata aacggtgttc cacctgctgc ttctcggtaa taagcccaaa gaattagaaa
     5821 acatggaaag ctgttttcta ttcttcgttc ttattactca aagcaagaca caggtgtcac
     5881 aacctcttgt ttttatgcta aaattgggtg agttaatctg gaaaaaggag aacaaaaatg
     5941 agccttaaag aatttgctga aaaaagtctg ctcaaacctt gggatgtttt tattattttg
     6001 cttttgactg ttctttcttt tttaccagtc atgatttttg gtcttcagca aaacaccgca
     6061 acagcagaaa aagaagcggt actgcgtgtg gatggcacag aaatcaaaac attccctttg
     6121 atggctggag aagagagcaa cacatatact tacaaagatg aacacggaga ttataacttg
     6181 atcgagatag atggcgatcg agtacggata aaagaagcag attgcgatga ccagatctgc
     6241 gtacgtcgag gctgggcaac gaaaaatggc gaaaccatcg tctgtttgcc acataaatta
     6301 gtgatcgaag tccgttcaac agatggaggt gacgaagaca gtctgattta ttagaccttc
     6361 acacaccatg agtaaattac aaaaaatgat ttatatttcg ctacttgttg cacaaggagt
     6421 gatcattggt ttattggaaa atatgatccc ttatcctttt tcttttgcgc ctggtgcaaa
     6481 actaggctta gccaatctaa tcacgatcgt tgccattttt accatgaaaa aacgagacag
     6541 cttcttacta ctttggctac gactattcct gactactttg ctaggcggaa cgatttccac
     6601 attcctttat agtatgagtg gtgctttgct tagttatttt ggaatgttat tggtcaagca
     6661 attaggacca aaacgtgtca gtatcatcgg aattagtgcg gccggcggtt tcatgcataa
     6721 tgtcggacag cttttgatgg cttctttcat tgcacaatca tggacagtca tgttgtactt
     6781 gccagtcctt tcagttttag ggattttatc agggattgca atcgggatcg cagcgaatta
     6841 tcttttacga catgtgcaga cacttcaacg attccaaaaa gattatgagc agggaaccaa
     6901 acaaaaatgg agcccaatgt ttaccaaaaa ataatcgtca cacaaggagt ttttttatga
     6961 agctacatcc aatgtgggaa aactatcctg ctttaagtaa agaattgaca gaaacactaa
     7021 aacggatgga agaaactgtc cgcctgaaaa acaaacctgt cgaacaagca atcaaagaaa
     7081 cgatccatgc cggcggaaag ctgttgcgtc ctgcctatca gctattgttc tcacaatttg
     7141 gaccagagca agatcgagac aaagccatcg ctttggcagc ttctatcgaa atgctccata
     7201 cggccacact gatccatgat gatatcgttg atgaagcgga tctgcgacgt ggtcagccta
     7261 atatccgtag tcagtttggt aatgtcgttt ctgtctatgc aggagactat ttatttgtct
     7321 gctgttttaa actattgtct gattactcca cttccttgaa aagtctccaa ttgaattctc
     7381 gcagtatgga aaaagtattg aatggcgaat tagggcagat ggatgatcgc tataattatg
     7441 aactttctgt aaaagaatat ttggaaaata tttcaggtaa gacagctgaa ctgttccaat
     7501 taagttgttc tgttggcgct tttgaaagtg gaacaagcga gcgcttcgca aaaaaagcag
     7561 gagatatcgg actttctatc gggatggcct ttcagattat cgatgatatt ttagattata
     7621 caaaagagag ccaggaaatc ggcaaacctg tactagaaga catgcgtcaa ggggtctatt
     7681 ctttaccgtt gatctactct ttgcaaaaaa acaaaccaaa gctactacct tatttagaga
     7741 agaaagcggc aatgacagaa gaagatgtcg acgccgtacg caaaatcgtt gaacatacag
     7801 gaggcgtgga agaagctagg aagttagcgg cctcttacac agaaaaggct ttgaaggaaa
     7861 taaagaaatt acctgccacc tctcttcgaa caaaagagaa tctcttttcc cttacccaac
     7921 tgattttgga tcgcaaagac tgaataggga aaggttcgat acgtaaataa atttctcaga
     7981 aggaaatcta cgtgtttttt gacaaattga attgtagttc ttgtatttat gataaaaagc
     8041 aaaaataaag agcaacgtcc gttagcgacg ttgctctttt ttatcttgaa tattttttta
     8101 ccttttcgat ttcttataac tcataaaagt gattcttaaa ccgattacaa gtaatataac
     8161 gcctgcgagt gttatccaat tattcgattg acttccagtt ttaggaagtg ctctttttga
     8221 tttgtttcca ttgtcattgc ttgttttatt agttaagtta aagttcgtcc tgttatccga
     8281 acttgttttt gagaaggaga cacttgcatg acgtgtatcg cttgtggtag acgacgtgtc
     8341 tgtactatcg cttgaagttg atgaatctga gctatcactt gtggtagagg atgtatctgt
     8401 actgtcactt gaagctgacg tgtccgtgct atcacttgta gtggtagatg aatctgagct
     8461 atcacttgtg gtagaggtag tatctgtact gtcacttgaa gctgacgtgt ccgtgctatc
     8521 acttgttgtg gtagatgtat ccgtactgtc gcttgaagct gacgtgtccg tgctatcact
     8581 tgtggtagag gtagtatctg tactgtcact tgaagctgat gtgtccgtgc tatcacttgt
     8641 ggtagaggta gtatctgtac tgtcgctt
//
LOCUS       DBBGSP010000095         8494 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000095 DBBGSP010000000
VERSION     DBBGSP010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.095"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..149)
                     /locus_tag="ACIZE9_002862"
     CDS             complement(<1..149)
                     /locus_tag="ACIZE9_002862"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC6094669.1"
                     /translation="MENHVLETGMQKITTHASITAKPFFEKRGYKVINEQTVELRGQL
                     FTNFL"
     gene            complement(593..1714)
                     /locus_tag="ACIZE9_002863"
     CDS             complement(593..1714)
                     /locus_tag="ACIZE9_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HGC6094670.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="ACIZE9_002864"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="ACIZE9_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HGC6094671.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="ACIZE9_002865"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="ACIZE9_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HGC6094672.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="ACIZE9_002866"
     CDS             complement(4304..5215)
                     /locus_tag="ACIZE9_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGC6094673.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="ACIZE9_002867"
     CDS             complement(5232..6239)
                     /locus_tag="ACIZE9_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HGC6094674.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="ACIZE9_002868"
     CDS             complement(6236..8365)
                     /locus_tag="ACIZE9_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HGC6094675.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8480)
                     /locus_tag="ACIZE9_002869"
     CDS             complement(8370..8480)
                     /locus_tag="ACIZE9_002869"
                     /inference="COORDINATES: protein motif:HMM:NF024254.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094676.1"
                     /translation="MMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1486 g         2681 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg tttt
//
LOCUS       DBBGSP010000096         8290 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000096 DBBGSP010000000
VERSION     DBBGSP010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.096"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(45..1511)
                     /locus_tag="ACIZE9_002870"
     CDS             complement(45..1511)
                     /locus_tag="ACIZE9_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HGC6094677.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1898..2494
                     /locus_tag="ACIZE9_002871"
     CDS             1898..2494
                     /locus_tag="ACIZE9_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGC6094678.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(2552..3034)
                     /locus_tag="ACIZE9_002872"
     CDS             complement(2552..3034)
                     /locus_tag="ACIZE9_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094679.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3140..3337)
                     /locus_tag="ACIZE9_002873"
     CDS             complement(3140..3337)
                     /locus_tag="ACIZE9_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094680.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3632..4390
                     /locus_tag="ACIZE9_002874"
     CDS             3632..4390
                     /locus_tag="ACIZE9_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HGC6094681.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4450..4878
                     /locus_tag="ACIZE9_002875"
     CDS             4450..4878
                     /locus_tag="ACIZE9_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094682.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4924..4996
                     /locus_tag="ACIZE9_002876"
     tRNA            4924..4996
                     /locus_tag="ACIZE9_002876"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4957..4959,aa:Gln,seq:ctg)
     gene            complement(5146..5517)
                     /locus_tag="ACIZE9_002877"
     CDS             complement(5146..5517)
                     /locus_tag="ACIZE9_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HGC6094683.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5732..5917
                     /locus_tag="ACIZE9_002878"
     CDS             5732..5917
                     /locus_tag="ACIZE9_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094684.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6000..6188)
                     /locus_tag="ACIZE9_002879"
     CDS             complement(6000..6188)
                     /locus_tag="ACIZE9_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094685.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6212..6475)
                     /locus_tag="ACIZE9_002880"
     CDS             complement(6212..6475)
                     /locus_tag="ACIZE9_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094686.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6633..6890
                     /locus_tag="ACIZE9_002881"
     CDS             6633..6890
                     /locus_tag="ACIZE9_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HGC6094687.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6961..7152)
                     /locus_tag="ACIZE9_002882"
     CDS             complement(6961..7152)
                     /locus_tag="ACIZE9_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094688.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7293..7613)
                     /locus_tag="ACIZE9_002883"
     CDS             complement(7293..7613)
                     /locus_tag="ACIZE9_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094689.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7636..8070)
                     /locus_tag="ACIZE9_002884"
     CDS             complement(7636..8070)
                     /locus_tag="ACIZE9_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGC6094690.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
BASE COUNT         2629 a         1635 c         1313 g         2713 t
ORIGIN      
        1 aggaactgct gcaaataagc aattcctgtt tttatgttca ttgattaatg aatagagccc
       61 attagttttt tgattggttc tttcacagta aatagcaaga taccaccgac gattgctact
      121 gcaccgataa taccgaagta agcagattct gttcccggtg tgtagaagcg tgcaatttgt
      181 gcattgattg cttgtgaaga agcatcagct aagaaccaaa tagcgattgt ttgtgattca
      241 aatgctcgtg gtgctaattt tgttgtcaca gacaaaccaa ctggtgaaag acacaattca
      301 gcaataacca cgatgaagaa acttcccaac aaccacaatg gacttacttt tccacttgta
      361 ccataaagca tacccggcaa catcaatagc aagtacgata atcctgcaaa taaaagtcca
      421 agagagaatt tcactactgt agatggttga cgttcaccaa gtttcgtcca catcgttacg
      481 aatactggtg tcagaataaa gatgaaaatt ggattcaatg attgatacca gcttgcttgg
      541 atcgttacac caaatagcgt agattgtgta cgttcactag caaataaagc taagatagat
      601 gaaccttgtt cttgtaatga ccagaaaatg attgctgcaa ggaataatgg gatataagcc
      661 catactcttg gtttttcttc agcagttaca tcttttgaag tcagcatttt gataaagtaa
      721 tacaacggta agataatccc caatacactg attgtattga caaaaaagtc aattgtcaga
      781 tgaccagtta gttgtgcccc gccgaatact gcagcgataa caacaagtgc gatgatcaag
      841 ttacggatga atcctttacg ttcttcagtt gtcaaaggat tcggcggtgt tgtacccact
      901 ccgtctaatg tcttgcgtcc ttggatgatg tattgtaata atccaaagaa catcccaata
      961 gcagctaaag agaaccctaa atgatagtta tattcttgac cgattgtacc aacgattagt
     1021 ggtgctaata atgcccctaa gttgacaccc atgtaaaaaa tcgaaaatcc tgcatctctt
     1081 cgcaagtcag tctttgaata aagatgtccg accatgccag aaacatttgg tttcaaaaag
     1141 gcggttccga taataatcaa tgccatcgaa acaaacaatg tacttacacc aaatggtaaa
     1201 gccaagacga tgtggccaag cataatgaaa actccaccga agaatacagt gcgttttgct
     1261 cctaacactc ggtcagatac ccatccgccg acgatactag acatgtagat caaagatccg
     1321 tagatcgaca tgatagctaa tgctgttgct cgtggtaatc caagtccccc gttggcaact
     1381 gtatcgtaca tataatagat aagtaatgca cgcataccgt aataactaaa tcgttcccac
     1441 atctcagtga agaacaaagt tgacaatccc ttcggctgcc cgaagaagcc cttgtcttgc
     1501 tgtttttcca taatctatac cccaattctt taaattttca gaaaatatta tacatcttta
     1561 ccgaaaaatt taactaaaaa acttatttaa gaaatataaa ctaattttct ataaaagcaa
     1621 gtaattttta atggcaatat cataaaaaaa agaagataga gatttaataa ttatatatca
     1681 gctgtttttt tcaaataagc aaaaattcct aaaacacaac aatgaaagcg ataactaaga
     1741 aaatccttac ataacgattt ttcttattaa aattgttttt tgaacttcgc ttattttttg
     1801 tgagcatatc tgtttactta ctttttgtaa ggtgctatac ttcatttcgt aatcaattaa
     1861 aaaaatgcaa aacgcaaatc aaaggagaaa ttttattatg acaactttta ctgacacttt
     1921 gaaaaaccgc cgttcaatct atcatctagg acgtaatgtt tcactttcta atgaagaatt
     1981 aacaactttg atcaaagaag caattaaaga aagcccaact gctttcaatg ctcaatcaac
     2041 acgcgcagtt atccttttcg gagatgcaca tgaaaaactt tgggaaatca ctgaagaagc
     2101 acttcgccca ttgactccag cagaagcttt cccaaataca caaaacaaat tagctggttt
     2161 caaaaatggt tatggtacag tattattctt caaagatact gacgtggtaa aaggtctaca
     2221 agaacaattt gaattatatg cagacaactt cccagattgg tcagaacaat caaacggaat
     2281 cgcaacagct aatacttggg tagcattagt tgataaagga ttgggcgcaa acttgcaaca
     2341 ttacaaccca gttattgacg aagcagttgc aaaagaatgg aatatccctt caaactggaa
     2401 actacgttcg caattagtat tcggttcacc agaaacaccg gctgaggaaa aagaatacat
     2461 gaacgatgcc gatcgcttcc gcgtatttgg ataattttat ttgaaataaa aaacagaggt
     2521 tgtgacaaac atcttgtcgc aacctctgtt tttattctgg atcaatcata atatcaatct
     2581 ctgcctcatc gtttaagcgt tgggacaaaa atggaactaa ttcttctaat gatgcagaaa
     2641 atttcagcat cggtcctcgc catccgtttc ggaaaaaatt catttttacg attttagaac
     2701 cttttggctg atataataca attttattga tctcagaaaa aggaacacct tttttgtcaa
     2761 agctattcaa aacaagtcct tcttctgtga ttcctctact gtccaacaaa aaactaataa
     2821 aaatcattgc tgacaagatc ccttttgcca attcatctgc tgtaggatga ctgatgagtg
     2881 tataccaaat gactagtgac actaagaagg gtatcaccaa gtagacccat cgatttcgca
     2941 cagtccgata aataatttct tttcgaacca gccaaagaaa taaaaacatc acaacaacga
     3001 ataaaaacaa tagaaccgta aagaatgtta ccatgacaac tcgcctcgct ttttcttctc
     3061 cagaaaatag gaaaagaata ctgatttacc ttctcaaaga aattggactt gcagcacgcc
     3121 gcacgtccaa ttgttttctt tattcaaatg tatcatattt tgcaacaacc atgcttgctt
     3181 tttcatctaa taattcttgg tcctctgcag cacattgggc aactttgacc acggcgcagt
     3241 ttgtcatttt tgatacaact tcaccaatga ccgtttttgt aaaaccaatt ggtttgcatg
     3301 catattgttc tcctaaatta atcatttctt ccgtcatcaa aatcctccta aactgctgga
     3361 acttttctcc acattaccac tgctatttct ttggagattt aactcattga tttttattta
     3421 cagttaaaaa tcaaccttac aggcattata gcgtactgtt ttcgttttca caattaaaac
     3481 agctgttgta tttagaagaa tttttttcaa aaaattaaaa catattcctt aaaaactaat
     3541 tatttcctac atattaaaat ataatacttc catttccaat aaaaatacat ttataatagg
     3601 aaagataaac agctgaaaag ggagatttca aatgaagaaa aaaacgttca aaaaactatt
     3661 gtttctaggg ggcacagctg ctcttttatt aagcggtaca agttattacc tacatatcca
     3721 ttctccagaa catacaatga acactgcaca aaaaagttca acacaaaaaa cgaaaaagac
     3781 aaaagagaaa gcagaagttt tactagatgt tccattagag agccagtttg attctccttc
     3841 tttagaaaat ggctgtgaag tcacttcgct ttctatgctt ttatcttttt atggttatga
     3901 aacaactaaa aaccagttag ctgagcaatt ggattacgtc cctgttttca atgcagatgg
     3961 gactcatggc gatcctaatg aaggatttgt tggtgatatc agtggcggag actgggctat
     4021 ggtcgtctat gttcccccag ttgcctccct tgctcagcaa atcgtccaaa cggattatca
     4081 cacttttcca aaaaccgatg ctcaactcga tgatatcaaa aaagcactat ctaaaggaaa
     4141 tcctgtctgg acttctgtga ctatcaattt tgaagtccca gatgaaactg attttatgac
     4201 ttggaccaca aataatggag aagtaagagt cactcctctt gttcatgctt gtgtagtcac
     4261 tggatatgac aaagaaaata tttatgtcaa cgatccctat ggtgtaaaaa atcgagcagt
     4321 accgatcaac gatttttcgg cgattttcac tgcaatgggt ggacagatgc taactttgga
     4381 gaaaagctag taattcaaac aaaaatccct tatactcaag ataccaaacc tttgaaggga
     4441 gcgtagataa tggaaaaatt cacacataaa aaaatggatc caaatgaaat tccgattatt
     4501 tttgtccgtg actgcaaggg aaatgttcaa ggtaaagtct ctattaatga gtggaacgag
     4561 cgtcgcagac ctgctaccct caatgaactg gaaatcaaat tgtatcgtca atctcttgtt
     4621 tattacgcag atcaagagta cgagaaagcc accgatttat tgaaatttct aattgctcga
     4681 acagagtata ctcgctttga atatattgaa cgtttagcaa acatctatca tattatgaat
     4741 gaacctgtca aagaatatca gttattggac accgtcttgt cagtagcaga actgattgcc
     4801 cttcctgctg gattagaaaa gaaactagta cgccgccttt tacgagtaaa gcaacaacta
     4861 tccgatcaag aaaaataact tgcgtttttt taggaaagtg ctatgattat tttgttgaat
     4921 aaatgggatg tagccaaact ggtaaggcac ttgactctga atcaagcaat tgtaggttcg
     4981 aaccctgcca tcccaatttg atgtgcttgc tgaaaaaatg aaccccctgt aaaagaacaa
     5041 tctttttgca gggggattat tgtattattt ttactacttg tatttagttt acataattaa
     5101 attatgaata ataaaatcgg gcgtattctt aatacaaaaa ctgatttacc caataattgc
     5161 taatgctttc tccggaactt tttctctagg aacttcctca tacgtttcta tgtgtgctcc
     5221 tttattgcta attttcaaat aatgattttc ttttaacaca gaaagaccat taaattcaac
     5281 cgttcgttct ttcccattgg catcagcagc tttctgcaca taccttgctg taccatattc
     5341 atttacttcc tctggttttt gtgtctttac atagacctct cctttttcaa ctaatggatt
     5401 tagctgatca agtataccag ggatttctcc ataacttcct tcagtataat atttcagtcc
     5461 aaatagcaaa ataccactaa tcgccgccag tccaatcaaa tatttaatca ctttcatctt
     5521 tctacctcct tgttatatat tcagtatatg ggtcagttaa agaaattcca tccgtcccaa
     5581 gttggagatt tttctcctac tttagaagcg agaatcgagt gtttttttag taaaaatgat
     5641 cgttatttga tattattgac gtgtggataa atcagttttt ctcgttttgt ccatgtaaaa
     5701 aatcatgttg atagcaaagg atgtgttcaa aatgaatcaa gaagaattat ttcaaaaagt
     5761 caaggaaatg attaagaacg gcaatttcga tggcgcaaaa cgatttatcg aagaacataa
     5821 agaacaatta ggaccttata aagagaaagc ccaaaatctt ttaaaagatg taaatatcga
     5881 cagtgtcaaa aacaaattta aaaatctatt caaataagta aaactttcac ttttgtaaaa
     5941 tcaaaggagg acaatgctgc tgcatcgtcc tcctttggtt cttttctgaa tacttcatac
     6001 taaaataaac gtgtcggatc gtaatgataa gtcacattgc cgttcagtga ggcttttccc
     6061 accacatatt tacgattctc caacttcagc cacgcttctc gaaaagccat taattcttct
     6121 ctttttacat caatcttttc gatttttcca tcgatcaaat cttgaataag ttgttcatat
     6181 ggattcattt ttttcctcca tctgctgtca atcaataagt tgtaaaaata ggttcatatg
     6241 cttttttggt atctagatct tctctgactt tgactgtcgt ataaataatt ttttctactg
     6301 ggatactata ataacttcct tcaccattat tgaatcggtg aacgtctttc tttgctaaaa
     6361 taccatttat tttattcgtc agtacacgtt gttcgacact gttacttaca acatagtaaa
     6421 tcacccgaat attattgatc aaatgcaaat cgatttctaa cactacatga tccatgaaaa
     6481 tcccactcct tctttcactt tgattatagc aagtttctcc tctaatttca aaatcgatac
     6541 agattttacc ggataaatcc acaaaactgc ttgcgccatt tcgcacaaag tgttattttg
     6601 tatcatggac tttatttatc ggaggcaata gtatgatcgc gatcggtcaa tttgtttttt
     6661 atattccttt ttttattatg ataagcattc ttttctatta cataaaatgg acaaaaaaga
     6721 agttttcagt tttactggcc tctttacctg ctgtatattt tacttatcaa attttttctt
     6781 ttaggcattg ggaaacaacg tctgtattaa taacacacat catcgaattg acgctttcag
     6841 taatttttct tattatttgg atctattttt tatataagaa tcagaattga atccctcgca
     6901 tgtttaaaaa gaaaacgatt aaagatgcag caaatttctg ccgatcttta atcgtttttt
     6961 ctattctgtt ataccaaaaa aatgtttgaa tcggtgaagg atcgttcctt gttttaattc
     7021 tataaattct tgtgcgatcg ggtacttttc ttccaaattt tctttgttct tttcgatcag
     7081 gcttttcgct tcttcatatt ttttatctgc acatagtgct tttacttcct gtaatacttt
     7141 tcctgcttcc atttgcctca ccctcttgcc attttattgc tttaagtttt atttaagtta
     7201 tacgcattat tctagtttca tcccaaataa ccttttttca tttttactcc tcgaactaat
     7261 cagttttcta aaggctgatt ggttcgtctt ttttattttt cctccatttc attctgctct
     7321 tctgttaatt tatctaatgc tttgattgat gctgcggctc ttgcataatc atagctgtat
     7381 aattccataa atttatcagg cagaacaaac cacgctggat gataaccgtt agctgtgaca
     7441 gggaatcctt tatcttgttg gttatctcca tcccatctca gagcaacacc tttttttcct
     7501 ttccacttta ctaaagcgat cgagtatccc ttctttgttt gtgtgccgtc ttcaataatt
     7561 gctaaaattt ctattttttc ttttggcgca cggacttctt gaggacgaac cattttctat
     7621 tcctccctta tctcattact tcacgaccaa cacactgcaa ggggcatgtg atacgacata
     7681 agaagcggtc gatccaacta atgcttgttg tatagcacct tttcctgtcg ctcccataac
     7741 gatcaaatca atattttctt gtccagggat gacattggca atcaaatttc ttggatctcc
     7801 agtttcaact attgcgtgga tctcagcaat gccgtactct ttggcatcat tgattttttt
     7861 cagcatggct acttctgttc tttgtttttc atctgcatag atttttgaaa aggcataggc
     7921 actatgggtc agctcaactt tgttgatgat tgacacgata aataagtggg cttcattgtc
     7981 ctttgctaag tcaagggctt cagcgaacgc tttgatcgat tgtcttgatc cgtcaactgc
     8041 taccatgatg ttctggtatc ttttactcat tggaaccgcc tcctttttct tttattgtaa
     8101 catctcaagc aaaaatacaa aaaatatacg caatatgtaa ataaaatgat gaacaaaagc
     8161 aatttctttc aagttattta tacatttctt ttctcatcag aacacctgtt ctaatcccat
     8221 tatttctgca ttatgtgaaa ttcctcatca tttttcacat cgagcgaaca tcattctgtt
     8281 acaaaaaacg
//
LOCUS       DBBGSP010000097         7854 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000097 DBBGSP010000000
VERSION     DBBGSP010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.097"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(646..1992)
                     /gene="gor"
                     /locus_tag="ACIZE9_002885"
     CDS             complement(646..1992)
                     /gene="gor"
                     /locus_tag="ACIZE9_002885"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGC6094691.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2126..3379)
                     /locus_tag="ACIZE9_002886"
     CDS             complement(2126..3379)
                     /locus_tag="ACIZE9_002886"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGC6094692.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(3385..4308)
                     /locus_tag="ACIZE9_002887"
     CDS             complement(3385..4308)
                     /locus_tag="ACIZE9_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGC6094693.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4529..7021)
                     /locus_tag="ACIZE9_002888"
     CDS             complement(4529..7021)
                     /locus_tag="ACIZE9_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGC6094694.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(7028..7495)
                     /locus_tag="ACIZE9_002889"
     CDS             complement(7028..7495)
                     /locus_tag="ACIZE9_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGC6094695.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7631..7704)
                     /locus_tag="ACIZE9_002890"
     tRNA            complement(7631..7704)
                     /locus_tag="ACIZE9_002890"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7668..7670),aa:Arg,seq:acg)
     gene            complement(7762..7835)
                     /locus_tag="ACIZE9_002891"
     tRNA            complement(7762..7835)
                     /locus_tag="ACIZE9_002891"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7799..7801),aa:Pro,seq:tgg)
BASE COUNT         2190 a         1705 c         1265 g         2694 t
ORIGIN      
        1 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
       61 actggctttt gaacaccgtt tatcagaggt tgtaaaatca gtgttttgtc ctgagtatta
      121 gagaaacaaa tggaaaaata gttcctcata ttttgccgtt ttttgagcta ataccgaagg
      181 acagctgatt gaacactatt tgttcggaaa aagtgactaa ctatgacaca atttttttca
      241 cagtcccttt tttcacttga tttgattcgt accagcgaac ttgacgagaa ctttcttggt
      301 ttggtaacta tatggtattc ttttaacatc ctcgtttgct tcttctaatt tatttataca
      361 aagtcacact tttttaaaca tctgttcttc gatacatttc tatttctttt aaacatcgat
      421 accaatattt tgaacttaag agtgcatacc aaatggattc atttactctt cgtcagttac
      481 gaagataatc aaaatctcca acttccctac ttatttcgtt ttgagaatta tcgaagcaat
      541 cttacataaa taactaaaaa acaaaaaacc agaaaatcag tatactgatt ttctggtttt
      601 acatggtttg ttcaataaaa agctgttgga actgttaata ttaaattatc gcatcgttac
      661 gaattcttcc gctcctgttg gatggatggc tactgtattg tcaaagtctt ctttagttgc
      721 acccatcttg atagccacgg caaaaccttg cagcatctca tcgacaccaa caccaatagc
      781 atgtaagccg acgattcttt cttcttttcc gacacagatc aatttcattt cgcatttttg
      841 gcgataatca tttaatgcaa agtacattgg ggtaaagcgt gaacgataaa ctttcaattc
      901 attttcgcca tatttttcca atgcttcttc ttctgtcaaa ccaattgttg caattggtgg
      961 atgcgtaaag acgactgtcg gaacaagttt atagtcaaga taagaatctt tctttccatt
     1021 aaataaacgt tctgataaac gtctaccagc tgcgattgca acaggagtca gatctaattt
     1081 accgatcaca tcaccaacag caaaaatatg ttcatccgtt gtattttggt atttatctac
     1141 tttgataaac ccttttttgt ccaattccac atttgtattt tccagaccta atttttcggt
     1201 attcggtaca cgtccaccgg caaaaagtac acaatcacca gttaaggttt caccattttc
     1261 aaatagcacc gtatattcgt cattgttttt agtaatttct ttagcaatat gatgtgcgta
     1321 agtttttatt ccagcttctt ggtacatttg gatcaaattg tccgaaagca ttttatcaaa
     1381 cgttctaagt ggtcgttctt ttcgatatgc ccacatgact tcactaccta aaccacgaaa
     1441 tacacctgaa agttcagccg caatgtatcc agcacctaaa acgattgctc tcttaggtaa
     1501 ctctgttaat tcaaaaaatc catttgaatc aattgcgtat tctccaccag gaatggtcat
     1561 tttacttgca cggcctccag tagcgatcaa gattttagga gcacgatagg tttcaccgtt
     1621 tacttcgatc gtttgactat cgataaaagt agcgtaacct tttatagcct cgacatgatt
     1681 gctatctaat cctctttgat aagcaccgtg tagaaaatca atatattttt ctcgtctttc
     1741 tactagaccg gcgaaatcaa cattttttaa atctgcttgg ataccgtaac ttgaggcatc
     1801 tcgttcaatt gtttccaaaa tcgtacttgc ttgccacata acttttttag gtacacaacc
     1861 gacgttgaca catgttccgc ccaattcatt cgcttcaatc agcaaaactt ttgcgccatg
     1921 catccctgct ctgtttgctg aagcaatacc gccagagccg ccaccaatta cgatgtaatc
     1981 atatatttgc attttgttcc tccttattga agagatcaat caaaaccttt atttaacgat
     2041 cctttttcta cagaaaacaa gtgtaacact tttcttgaat tttgtatgcg aagatgctta
     2101 aaacagggat atatcagctt tttccttatt tacgttttcg gatcatatct ccaggtttca
     2161 ccggctgtgc gactggcata gttaaaatca tcattggatt tggtgctcgg tcaatggatt
     2221 cgccttcttc attatgcata acttcaacgg tttgactgaa atgactgaat cctggaccat
     2281 aaaattcgat ttcatctcct acagaaaaca agtttctctg acgtatcgta gcaatctgtg
     2341 ttgcctcatc ataagataat acttcaccga caaatttata tactgggatt ttacgacgtt
     2401 caccgaataa ttgttcgttt tcagttggtg tattgtagta aaaacctgta gctaattctc
     2461 gttgtgctac tttccataac tcgtcgatcc attcttgctt gcagacatag ttttcaggat
     2521 cttccatata actgtctaca gccgctttat agacatttga caccgtagat acataatgga
     2581 tcgatttcat tcttccttcg atcttgaagc tgtctacgcc gttttcaatc aattctggaa
     2641 tatgttcgat cattgacata tccactgcac tcatcgagaa ttcttcttcc acttcgcctg
     2701 tatcagttaa actgtttcgt tcttgaccaa aaggcatatc gaacaatcca tacttccagc
     2761 gacaagattg agaacatccg ccacggtttg catcccgcat cgacatatgg ttggacaatg
     2821 tgcatcgacc agaataagag atacacatgg caccatggat aaatgcttcg atttcggtat
     2881 ccgtattttt acgaatctct gccacttcct ccattgaaac ttcacgagct aaaacgacac
     2941 gttccaaccc ttcttctttc cagaattcca atgtctcaaa attagttgct gaagcttgag
     3001 tggataaatg gatcggcaga cctggggctt ctgtcgcaca aatttcgatc aaagctggat
     3061 cagaaacaat cactgcagaa ataccgacat cacgcaaact gcggaaaaat tcccctgctc
     3121 catcttcatt tccttcatgg gtgaccatat tagcagcaac gtataccttc gcatcatgtt
     3181 cttttgcaaa agcaactcct tcagccattt cttcataagt aaaattacct gcacggcttc
     3241 ttaaaccata tgcattcccg ccaatatata ctgcatctgc tccataatgg atcgcggttt
     3301 ttaacttttc cagtgttcct gctggcgcta ggatttctgg tcgtttcaat tttcttttta
     3361 ctgtcatttc tttcatcata ctccttattt gatagcagaa ggatcaatat aaaagaatcc
     3421 tgtatctaat tcacggtttt caggatgcaa tttactgatt tcgctagtca ttttttccgc
     3481 tttttcttga tcccagctac cttctaaaat ttgttttttt gcttcggcga atagtcgagt
     3541 gatgtttacg aatttttcgc ctggagtaaa taatccgtcc aatttccatg tacagtaatg
     3601 atgctgataa agttcattca attcattcga gagattcaga tcattgctgg caaaaatatg
     3661 tgtgccatga ctatcttcat aaatagaata atgtgtctct tcttttttag gttccgagat
     3721 aaaaagacct ctttcacgat ctttttgttc gtcttgtttc gtatagttat agtaattctg
     3781 tagcagtgga cgtttggatt gatggatgca tgtagcacca tacacaaggg tttctacagg
     3841 aatatcgagt ttttcttcca tcgccttcat ctcttcaaaa ggaacttcac gagcaagtac
     3901 tgctccaact gcgccttttt tcgcccagaa attgatttga cgtgcgctcg ttactaatgt
     3961 ttcagcatca taaatatacg gtatacgcaa ttcaggattt tttttcatcg tataaataat
     4021 acctgtatca ccaactgtga tcacatctac gtttatttct tttaaaaaag ccaaatattc
     4081 aggtacattt ttcatttttt caggatgaat gatcccattt acagcaatat tcgctttttt
     4141 accatacttg tgtgctaatt ctaccaattg tcgctgttct tctcgtgtaa atgaagcagg
     4201 cagacgcaat ccaaattgct cttcaccgaa atatagtgta tctgcacctg cagcaagcaa
     4261 ctgttctgct tgttcaatag tttctactgt ggttatgagt tcgatcataa ttttctcctc
     4321 ctacaacttc ataatagtag catagctcta aaaactttcc aatacttctt ctatttaaag
     4381 tcggattttt gaaaattatt tcacaaaaaa tcaaaataaa gttcgatata ttctgtccaa
     4441 atataaaaag agattgtgac aaaaatcttg tcacaacctc ttaatcaagt cttactatta
     4501 taaaaattca gctacacagg ccaagtaact atagggaacc tactgtttcc tttttaggtc
     4561 cgcgaacatt caatgtgatc ttaccttttg aagcacctac tgttacgtgg tcacctaaac
     4621 gaatttctcc gccaagcaaa gcctcgctca atcgatcttc aatttctttt tgaagtgcgc
     4681 gacggattgg acgtgcacca tattcaggat caaatccagc tttcccgatc acatcgattg
     4741 cagatggtgt gattttcact tgaatatctt gttctttcaa tcgtttgata atcgctttgc
     4801 tcatgatttg gacgattgta tggatttcat ctttactcaa tgaatggaag acgacagtct
     4861 catcgattcg attcaagaat tcaggtcgga aagctttctt taactcttct aagatacgtt
     4921 tttgcatggc tttgtgatct ttagtaacat cttggacatt gaatccgaca tttttttctt
     4981 ctcgaatttg tgtcgctccg atatttgaag tcataatcat gattgtattt ctaaagtcca
     5041 cttttctacc tttagaatct gttaaatgac catcatccaa tacttgcaga agtaaattga
     5101 aaacgtctgg atgtgctttc tccacttcat ctaagagaat cactgaatat ggtttttgac
     5161 gaattttttc tgtcaactgt ccaccttcat cataccctac gtatcctgga ggagacccga
     5221 ttaatcggct tgtactgtat ttttccataa attctgacat atcaacacgg atcagggcat
     5281 cttcacttcc aaacatgact tctgaaagtg ctttggccaa ttctgttttt ccgacaccag
     5341 ttggtccaag gaacatgaat gaaccaattg gacgatcagg atctttcaat ccgcttcgtg
     5401 cacggcggat cgcacgtgaa actgctttga cagcctcatc ttgaccaacg acacgttcat
     5461 gcagaagtcc ttccagttct aacaagcgtt cgctttcttt tttctccaac tgctgtagag
     5521 ggacaccagt ccactccgat acaactgtag caacatcttc ttctgttaca cgatcagaat
     5581 aaccttgctc ctgttttgct tcaattgcag aaactttttg cagcttttta cgtagtgctt
     5641 tttcttgtct gcgtaattga gcagcatttt caaagtcttg tttttggatc gctgcttcct
     5701 tttcttgtac tagttcatcg atttctagtt tgatcacagt tgattttgtt aagtgatcgg
     5761 tttgatccaa acggactttc gctgctgatt catcgatcaa atcaattgct ttatcgggta
     5821 gttgacgaga agtgatataa cgaacagaaa gattgactgc tgctcgtaca gcttcatctg
     5881 tgatctccac tccatggtgc tcttcatatc ttgtacgtaa tccttgaaga atcacttctg
     5941 cttcttcagg agttggctca tctacttgaa tgcgagcaaa acgtcgctct aatgcagaat
     6001 ctttttcgat atatttttga tattcatcta gggtcgttgc tccgatcgtt tgtaattctc
     6061 ctcgagctaa cgccggtttc aagatattcg aagcatcaat tgctccttct gctccacctg
     6121 caccaattaa ggtatgcaat tcatcaatga ataagattac ttgaccatca ttatagattt
     6181 cgtcgatgac ctttttcatt cgatcttcaa attcaccgcg atatttcgta ccagcaacca
     6241 aagatcccat atcaagcatc atcaggcgct tttcttgcat gtcttctggc acttcaccta
     6301 aaatgatttt ttgagctaac ccttcagcaa tggctgtttt gcctacacca ggttcaccca
     6361 ccagtacagg gttattcttt gtccgtcggc taagaatctg gataagccgt ttcacttctc
     6421 tcgaacgacc aacaactggg tccagcttgt tttcttttgc taatttcgtc aaatcacgtg
     6481 ctaatgaatc tagcgtaggt gttccttgcg gtgtttgccg tttatcttgt acatttacat
     6541 ttctacgacg attcattcct tttccagcag aatcaccagc tagccccatt ttttgtttca
     6601 gaacttgacg ggcttttgaa aggctgatac ctaagttgat catgattcga gtagccatga
     6661 tactttcatc ttttaataag ctcatcaaaa tatgttctgt tccaactttt tgagaaccag
     6721 ttttcttcac ttcgctgcta gctaaagcaa aaacttgttt cattcttggt gaatatggaa
     6781 gaaagactcc tttagggtaa gaacggatac caccataacc aatcagatgt tcaatttctt
     6841 cataaatttc cgtttcattc aaatccattt cacgtaatac ttttccagca attccatttt
     6901 gctcgaccac taaggctagt aaaacatgtt ctgaactaac tgattgatgt ttcaaccgtt
     6961 ttgcttcttc ttgtgcaatt tctaatactg cttgggctct ttcagtaaaa agttcttcca
     7021 tctaatctca cttcccatct tcataactta aacgttccag aaatgctcgg agaatccgag
     7081 cacgtgtatg atcttcatat tcattgaaat tcaatgtgtt ttttgcaatt gcactcaaca
     7141 tcaagtttcc ttcttttttt gtaattattt ggtcttcata aagtttttga ataatagcaa
     7201 aagcattttt ctcactgatt gtatcatcaa ataactgatt tatctgctca agtaattgtt
     7261 ttttatctga aatccttact tttgcaattc gtatataacc accaccacca cgtttgcttt
     7321 ctactagata accacgttgg atggtaaaac gggtattaat cacatagttg atttgtgaag
     7381 gaacacagtt aaagaggtct gccatttcaa tccttcgaat ctcgatcatt tcactatttt
     7441 ccagaatttt ctttatatat gattcaatta aatccgaggt attctgatgt gccatcttat
     7501 tcattccctt tgactaatat tgaccttaat tataacgaat ttgataatag aaagaaagaa
     7561 gaacgctttt tgttaaataa atcctttaga atcaacaaaa aaaaatacgg aatatactat
     7621 tccgtatcga cgcgcccaag aggagtcgaa cccctaacct tttgatccgt agtcaaacac
     7681 tctatccagt tgagctatgg gcgcatattc aatttaaaaa aattataaat catttgaaaa
     7741 caaaaagcaa gataaaaaaa atcgggaaga caggattcga acctgcgacc ccttggtccc
     7801 aaaccaagtg ctctaccaag ctgagctact tcccgtttaa aaaataaaaa agac
//
LOCUS       DBBGSP010000098         7598 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000098 DBBGSP010000000
VERSION     DBBGSP010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.098"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(136..426)
                     /locus_tag="ACIZE9_002892"
     CDS             complement(136..426)
                     /locus_tag="ACIZE9_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094696.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(544..804)
                     /locus_tag="ACIZE9_002893"
     CDS             complement(544..804)
                     /locus_tag="ACIZE9_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094697.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(941..1354)
                     /locus_tag="ACIZE9_002894"
     CDS             complement(941..1354)
                     /locus_tag="ACIZE9_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HGC6094698.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1810..2295)
                     /locus_tag="ACIZE9_002895"
     CDS             complement(1810..2295)
                     /locus_tag="ACIZE9_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094699.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2434..2649)
                     /locus_tag="ACIZE9_002896"
     CDS             complement(2434..2649)
                     /locus_tag="ACIZE9_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HGC6094700.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2873..3673
                     /locus_tag="ACIZE9_002897"
     CDS             2873..3673
                     /locus_tag="ACIZE9_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC6094701.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3692..5560
                     /locus_tag="ACIZE9_002898"
     CDS             3692..5560
                     /locus_tag="ACIZE9_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HGC6094702.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5553..6044
                     /locus_tag="ACIZE9_002899"
     CDS             5553..6044
                     /locus_tag="ACIZE9_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HGC6094703.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6032..6586
                     /locus_tag="ACIZE9_002900"
     CDS             6032..6586
                     /locus_tag="ACIZE9_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HGC6094704.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6604..>7598
                     /locus_tag="ACIZE9_002901"
     CDS             6604..>7598
                     /locus_tag="ACIZE9_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HGC6094705.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2235 t
ORIGIN      
        1 tgttactatg aataacataa taagaaagta aagtggattg atttgagatc tttttatact
       61 tcaaaaaaga taacacccaa ctttcaaaaa tatgttttgg aagttgggac aaacgagtta
      121 atacatttta atacattatt ttttattcaa aaaaaatagc acaatggcaa agatcgtaag
      181 agagatcata agccccaatg aatgactaaa aagaaaagca gaatcacatg ccatatcatc
      241 ccatatttct tcaagaaaat aaataagcgg gaaaaaggga aggaatagta gaacatcgat
      301 ccagcaccat ttttttcttc ttttgaaata acataaaaca ataaacatga acgtgcaggg
      361 aagtaaaaac aaagctttac tcataactaa caaaatacca gctcctttta tttttttctc
      421 ccccacattc aaagagtaac aatggtatgt acttaataat agaaaaatgg atcaacttgt
      481 atgaataaca gctgaaaaga tctgcaccaa ataaaaaact tccagccaaa actgactgga
      541 agtttatttt tttctgaaat attctaacac aaatatgaaa aagatggccg aagctaataa
      601 gccgatttcg tagcaaaaca atgagatacc agagtcgtaa taataaaatc ctctaatctt
      661 atggataaaa tagatcatcg gacaagcaga taagagtaag tatttgttag gccttttgaa
      721 taagtaaaag aaagcactgg tcattatgat aaatggtatc caaaacaaaa gtttacttaa
      781 gacaatcaaa tgatcaactc ccatattttt taccaagaga gatcataaca tctttatcgt
      841 aaaaacaaaa tatttttttg ctcattttga aaatttaaac atactcgttc ttatccaaat
      901 atataaaaat cgcccctcat tcatcgagag gcgataagtt ctaatttaac tcaatttttt
      961 ttgtttcttt tggctgataa gctgttttag gtaataccaa tttcagcaca ccgtttttaa
     1021 aggttccagt gattttttct tcatcaacat taggaagata gaatgaacgt ttgtaagaga
     1081 ccgaatgtct ttctttccgt acatagttgc catcttcttt atcttctgta tgggactcat
     1141 gattggcgga gatcgtcaaa gtattatctg aatattcaac tgtcgtgtct tctttgtcac
     1201 agccaggcat atcagcagtt agtttgtatt ctttttcatt ttcgactaaa tctacttttg
     1261 gataacttga aacacctaaa aaatcattga atgctggact aaacacgtca ttgaaatcag
     1321 ggaacatgtc gcgaatgcta ggtacatttg ccatttttga tcatcctttc aataagtatt
     1381 ttttatttat ccctatttac gtaataactc tattttgaaa aaaatgcaag tataatggtt
     1441 agctttgtga atatttcatc taatacgata caaaggctat ctttctaatt tgaaaaaggg
     1501 atcattaaaa taataagaag aaaatatgtc aaaaggtaaa aaagtaaatt cttctatcca
     1561 aatatagaaa aattgaatct agaaaaccgc ccgacaataa atttcattaa ctcagttgac
     1621 cgaaaatgaa gtagatacca aaaatttatc aagagagcaa gtagagaagt gagtatattc
     1681 ataagagaaa tagctgtaac gaattattag gttaatgcaa atgcttattt atactccgta
     1741 taactttctc agaaaaaatg ataccaataa tgacttgcta gtactgtaaa tccgtataat
     1801 atcatctaat caaaatggtg ttccatttgc atctgtcatc gtaatcgatc cttcgggtga
     1861 cactcgataa aaaccaacgc ttccagatcc tccttgggaa cggatttgtt tgctggaagc
     1921 tgtgaacaaa taatctcgat caattttttg ataaaagcta ataacaatat cgtcactttg
     1981 taattcggaa cggtgggcaa taagaaatag aagtgctttg tcagagtttt ctaatggaag
     2041 agaaggtaca gtgctttctt gcatttcaga tgttgaagaa atgctaaacg actgaatact
     2101 tgattggcta tgttgcgaat ctacattacc agtagaagta ttagtaatgg aagtagtaga
     2161 agtactttta gttgaaccaa cctcagttgt tgaaatggct gctgaagatt ctttaacaga
     2221 attctttgtt ttatatccac aggcagaaaa aagtattaca gttcccaaca agcctgcgta
     2281 aatcccttta tgcatgatag ctcctcctaa aatagattat ctttattcag tatatcactt
     2341 aaacaaagaa aagcagatgg tttaaaatga aaaaaccttc ccaataaagg gaaggttcat
     2401 gaagataata acttttttaa taattatagc tttctaatat ctttcatcaa cttttctagt
     2461 aatcattggg aaaaatttca agcagtagat cgcacaaata cctacgacga tataaatgat
     2521 cttcgcaaaa atagttgttg aaccaccagc aatcatagct actaaatcaa gttcgaacaa
     2581 gcctaccaac agccagttca accctcccac aatcaataaa gttaatgcaa tagcatctaa
     2641 agttttcatt agaattctcc tttcttaaat gataaaacaa ttatatatca aaaagagaaa
     2701 cattgcttat ataacgctca ggaattttag caatctatgc aaaaagatga aaattttttt
     2761 tgctcttcca ttagtacaca ttttttagct gaagctgtaa atttcatgtc ttaatttttt
     2821 ttagtgagct tttatactgg atttgtaaga aaaaagaagg agaggatcac atatgtcgga
     2881 ttggttggat attgcaggaa aagtagtaat tgtaactgga ggttcctcag gaattggaag
     2941 aagtatcgtc gaaaatttgt tgaagcagaa tgcacaagta gcgaattttg atgtaactga
     3001 atgccgtata cagcatgaaa acctactatc tttaaaagtc gatgtgtctt ctaaaacgga
     3061 catagaagaa gggatatata aagtaatgaa acatttcaag acgatcgatg gtctagtcaa
     3121 taatgcagga ataaatattc cttctcttct aatagataga aatcatccaa aaagcaagta
     3181 tgaattatca gaacaagttt ttgataagat gatcgctgtc aatcaaaaaa gtgtatattt
     3241 gatgagccaa gcagttggaa gaatcttggt gcaaaaggga tcaggagtga tcgtgaatct
     3301 ttcttctgaa tcaggattgg aaggatcaga aggacagagc tgttatgctg ctacaaaagc
     3361 agcgatgaac agttttactc gttcttgggc aaaagagtta ggaaagagga atgttcgtgt
     3421 ggtaggtgtt gcaccaggga tactggaaga aaccggtttg agaacacaag aatatgaaga
     3481 agctctttct tatacgagag gtataagcgt cgaacagctg agaaacggtt acagtcgaac
     3541 aagtacgatc cctctaggaa ggagtggtaa gctgcaagaa gtggcggatc tagtctgcta
     3601 ttatctttca gaaagatcaa gttatatcac tggagtcacg actaatattt caggaggtaa
     3661 aacaagagga taaaggatag gggggacgca cgtgacgcta gtaaacagat ggtaccaatt
     3721 attgaaatta ctagtcactc acaagaaagt ttcaatccag gaagtgcaaa aagaaatcaa
     3781 aaccagtaat caaaccataa aaaaagatat tggggagttg aatgaagaaa ttgccggtat
     3841 tgcaaaaatc atccaaaaaa acaaacattt tgaacttgaa atttatgatt ttgatttttt
     3901 tgatgagatc atgcaaggaa aattgaaaac agccagtgat ttcaattcgg catccaaaag
     3961 aatcgcttat ttactaaata ggctgatcga aacagaggat ttcttacgta tggatgattt
     4021 gtctgaagaa gtcggtgtca gcagaggaac agtggtcaag gatctaaaga cattaaaaga
     4081 gatgatcaat gattttgatg taaagattac aggcacacca aataaaggac taagaataat
     4141 aggagatgag ctagaattac gactactttt attttatttt gtttctccct acttttcaga
     4201 gacgaaaaca gaacagtttc tagaagaaaa acaagcaatc aaacattttc agaagaagac
     4261 gaatgctagt aaacaagaaa tcaccctttt aacgaaagtt atcggtattt ctttgaatag
     4321 aatctctagt aactatctgt tgaagaagcc catcaatcgt tacagtgggt gttttgaata
     4381 tatccaagaa ttcaatgaac tgatcaatca gttggaagaa atctatgaac taactttgag
     4441 ccaatatgaa aaagatttta tcagttttcc tttgaacatc atcaacacaa gtataacgat
     4501 gataaggaaa gctaactctg atttgcgctt atatttcgac cccatgatga tgcgtattcg
     4561 acgattagat ctcattgatc tggatgagtc cttcttatat caagagatga aacagcacct
     4621 ctctttattg ataaatcggg taatttttcg ttatcgattg actgatttat tttatggtga
     4681 gatagaaaaa aagtatcctt tttcttacca aatcgctagc gaatgcatac aagcattaga
     4741 agctatcttg caacataaga tctctaaagt agagatcagc tacctaacgt tgtatttgga
     4801 gttagcattt cgatatcaaa aagagcattt ttcctctaaa aaagtagcca ttgttcatac
     4861 gacaggaaaa ggaacagcat taatgatcca aagacaaatc aaaaggatat tggggaggga
     4921 tatacaaata acacatgttt cagaagaaca atatgaaaaa gtagatctaa acaaatattt
     4981 cgctgttttt acaacgattc cgttaaaaaa tgtaaatgaa gagacaccgg tgatccattt
     5041 gactaatctt tttgatgact cttggttaag ggcacaatgg caaaaagcaa aaaaaaagcg
     5101 attagccggg tttcattcta ctgttttttt ctatcaaata tggaaagaaa aaaagacgta
     5161 tcaagaatat ttaaacaaat tagtcgctcc tttgatcaga ggctattatg tggatgaaga
     5221 atttgaaaaa aggatcttga aaagagaata tcagcaaagc acatttgtta acaaagaatt
     5281 tgcttttcct cacacaacca accagctatc tcaacacatt gttttatcag tagggctaat
     5341 aactgatcaa ggtttagcag aaacaggagg aaatggagtt atttttttat ttgccatacc
     5401 tgaagaaatg acggctgaag ttgagaatga attatttgag ctatacgata tcctatttga
     5461 actcataaaa atgggaatag atgagtttat tgaattagca ccgacacaag aatcattttt
     5521 aaaactaatc aaaagtaaag gagagagact tcatgaatga tatgtatcta ttcatagttt
     5581 tcgcagcttc agcttatgtg ctgcaagcag ttatcagttg gaagcaacta aagcatttca
     5641 atcaaacata tagcgaactg cgaagaaaag gaaaagtagc gattggtaaa cgacctggga
     5701 aaatccgttc aggcacgatt gttatgctag ctatagacga tcatgatcaa gttttagaag
     5761 tcagaaaaat gcaaggggtt acatctttgg caaaatttca ttcattacct gtctatgcgg
     5821 gtgaagatat ccattacatc gatcgttacc atccctcagt tcgagcggaa gatcgtttga
     5881 cacaagcagc tttagaaaat gccagagaag tatacttacg aatagaggca ggaaatgaaa
     5941 aaagtgaaca accttcattg ccttttattg ctatgctcaa taattttcgg atatggaaaa
     6001 gtacgatcaa agaaaaaagg agtgacaaac gatggatatc ataacaaaat ttgctgaggg
     6061 atttatgagg ctgttccaaa caggtgcaga aacattcata agctggatga caggaatcgt
     6121 accagttgtc ttgatgctga tggttgcaat gaatacgctg attgcttttt taggtgaaga
     6181 ccgagtaacg aaagtagcca aattatcagc gaaaaatccg cttactcgtt accttgtgtt
     6241 accgttctta tctgctttta tgttgggaaa tcctatgtca tttacaatgg ctcgtttcct
     6301 tccagaatac tacaaaccaa gctattatgc tgctcaagct caattttgtc atacgagcaa
     6361 tggtgtattc ccccatatta atcctggaga attgtttgta tggatgggga ttgctcaagg
     6421 gatcgaaacc ttagggctaa attcgatgga gctggctatc cgatacttgc ttgtgggact
     6481 gctgatgaac tttattggtg gttggataac tgattttact actggatttg tatgcagaca
     6541 gcaaggaatc gttcttagca aaaaagtaga gctttcagtt gattagagaa aggagagttt
     6601 taaatgtatg gtgatattaa gatcgtaaga ggaaacggcg ggtatggagg tcctttgatt
     6661 attaggccga caaaagataa acacaagttc atctatgtca caggtggagg tgagaggcca
     6721 atgatcgtag ataaaataga agaactgaca ggtatggagt ctatcaatgg gttcaaaaca
     6781 tcaatacctg atagtgaaat cgcgcttgca atcgttgact gtggagggac tcttagatgt
     6841 ggaatttatc ctaaaaaagg gataccaacc atcaatatcg tttccacagg aaaaagtggc
     6901 ccattagcac aatatatcac tgaagatatt tatgtttcag cagtagggtt agaacaaata
     6961 cagccactaa tggaaactga tgataacaaa gaaacagtaa atactgcatc tccagataaa
     7021 aagtacaaat atgatacttc taaaaagata accgagcaaa aagcagagca gcaaaactgg
     7081 atagcaaaaa ttggaatggg cgcgggaaaa gtagttgcta cattcaatca atcagcaaga
     7141 gaagcagtag atacgatgat ccggacagtg atccctttta tggctttcgt ttcccttttg
     7201 attggtgtga tacaaggttc tgggatcggt aatgtatttg ctaacattat ggcaccttta
     7261 gcaggaaatg cagttggatt aacaatcatt ggctttattt gttcactgcc atttttatct
     7321 cctttgcttg gtccaggggc agttattagc caagtgattg gaacattgat cggtgtagag
     7381 attgggaaag gaaatattcc tccccaatta gcattaccgg cactatttgc tatcaatact
     7441 caaaatgcat gtgattttat tccagtcggt ctaggtttgg aagaagcaaa agctgagaca
     7501 gtagaagtag gtgtaccatc agttctttat tcaagatttc ttaacggcat cccacgagtt
     7561 atcattgctt gggtagcaag ttttggatta tatagctg
//
LOCUS       DBBGSP010000099         7153 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000099 DBBGSP010000000
VERSION     DBBGSP010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.099"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(1..1368)
                     /locus_tag="ACIZE9_002902"
                     /pseudo
     CDS             complement(1..1368)
                     /locus_tag="ACIZE9_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1611..2066
                     /gene="tnpA"
                     /locus_tag="ACIZE9_002903"
     CDS             1611..2066
                     /gene="tnpA"
                     /locus_tag="ACIZE9_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HGC6094706.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            2331..2429
                     /locus_tag="ACIZE9_002904"
                     /pseudo
     CDS             2331..2429
                     /locus_tag="ACIZE9_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2652..2882)
                     /locus_tag="ACIZE9_002905"
     CDS             complement(2652..2882)
                     /locus_tag="ACIZE9_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HGC6094707.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(3112..3930)
                     /locus_tag="ACIZE9_002906"
     CDS             complement(3112..3930)
                     /locus_tag="ACIZE9_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC6094708.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            4091..4780
                     /locus_tag="ACIZE9_002907"
     CDS             4091..4780
                     /locus_tag="ACIZE9_002907"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGC6094709.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4794..6296
                     /locus_tag="ACIZE9_002908"
     CDS             4794..6296
                     /locus_tag="ACIZE9_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC6094710.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            6309..6785
                     /locus_tag="ACIZE9_002909"
     CDS             6309..6785
                     /locus_tag="ACIZE9_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HGC6094711.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6882..6992)
                     /locus_tag="ACIZE9_002910"
                     /pseudo
     CDS             complement(6882..6992)
                     /locus_tag="ACIZE9_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2316 a         1131 c         1295 g         2411 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggatccg atttttggct actgctccga cttgtcctcg ataagaattg tagcgccgtg
      541 atttacgtgt gtatgtcgtt acttttattc ctagcttctt gatcaggcgc tgaactttct
      601 ttttattgat agagaaaccg cggtttctta gttcattggt catccgtaaa cagccataat
      661 ccttgtgctt ctcccgaact ttaagcattt ccgcttcaat ctcttgatct ggatttttac
      721 ggtccaatcg tttttgccag tacataaaga ttgccttagg gaactttaaa gtttctagaa
      781 gctcaactaa tttaaacggt cctcggaggc ttgcgatgat tcgtgcgatt gcttcattcg
      841 tcgttgttgg gcttcctgtt ttcgcagctt cctcaattct tttaaaaagg cattttcaat
      901 ttgaagggaa cggactcgtt tctccaactc ctcgatgcgt tcacgttctt tagacgttgc
      961 tttagttgta gattttttct tatttttggg ttcatttttc ttagacaaga taggtggaca
     1021 tcctttcgtt tttgagagtc catcgatccc accctcacgg aattgacgca tccaactagc
     1081 gatcaaatta gggttgttca tgttaagtgt gttggcaact tcacgatagg acagctcact
     1141 tgttagatat aactctatcg catccagctt aaattgaaca gaatattttt tcttttgtcg
     1201 ctttcttact agaccctctt caccaaattc ttgataggca ttgatccagc gcttcacttg
     1261 tgatggagcc ttaatggaat atttctttgc cagataatca cttccgcctt taccatccaa
     1321 gtaatcatga acgatcttta atttaagttc aaaagtatac ttagccataa aaaataccga
     1381 cctccaaaag ttagattttt tggtctaact tttgggggtc ggtacaaaac ttaaaagttt
     1441 tagacccttt tattttctta atgacttcag tcagttttgt gcgtaaagcg tgcgaaacaa
     1501 gaaaaccgcg cgtttctacg cgtggaagaa gtatctttag cgataaaaac tcctttcgat
     1561 atactagtga gtggctacca accgctcatc agatcgaaag gagttttttc atgtcaaatg
     1621 acgataaaag tttagcatat actcgttgga attgtaagta tcatattatt tttacaccaa
     1681 aatatcaacg aaaagtaatc tatgggcaat tacgaaaaga tcttggaaaa atacttagga
     1741 agttgtgcga aatgaaagat gtggaaatca tagaagcaca tgcaatgcta gatcatattc
     1801 acatgcttgt tcgagtacca ccaaaaatat gtatatccag ttttatgggg tatctgaaag
     1861 gtcgtagtgc ggtactaatc cacgagcagc acgcaaatct caaatataaa tacggaaaca
     1921 aatccttttg gtcgaagaga tactatgtga gtacagtcgg attgaatcaa aagacaaatg
     1981 aaaaatacat ccgtgaacaa gaagctgatg atcgcattcg atatattata agtaaaagag
     2041 agtacgtaga accatttaaa aaataaagag aagtaagtga gtgaagatga gcagttggcg
     2101 gtcttttaaa aatccccttt taaggggcag cgagtgtcga ccccttctag ggggattaaa
     2161 aatacacccg tcctcacggg tgtatgggtt actgatagac ttgattttaa ctggtgtcag
     2221 aaacttatgt ccagaaaggg tgatgaaatt ttggcaattt acggctattc aagaattagc
     2281 acaagcaacc aagattacaa aacacaaatt caaacattag aaaatgctgg cgcagaaata
     2341 atcttcctag aaaatcactg gattatcgaa cacctttgga agtatttttg agttacgtaa
     2401 gtattgatga tctgtctaac ttaatttgac aattaagagt atatttactt cagatggtaa
     2461 ggcaacaaaa taaaatacaa taggcagatg aactaataaa taaaatctgt attaaataca
     2521 gataaattaa tataaaaatc aaaaggatca taaactttta acaagtgatg aaatgggtgg
     2581 aaattgattc ttatagacag tttgtctcat aacattgaag tattttgcaa ttttagcatt
     2641 gaaacacttt tttaatcttc aacgttgttc ttataaacaa gatgattggg aatcttttga
     2701 attaacactg tatagcttag aacacccttt atagaaaaca ttcgcttagc aatcttaata
     2761 attccttgtg cccgatgtcg tttagattca gtaggttcct gctcatcgat catggaaaaa
     2821 atttgaagga tcagatcctt aataaattta tttaagagag gatgatccat tgcttcatcc
     2881 atactcgata aactagtgat aatgagctac acgtttttct ttcaagttga tcaatagctt
     2941 ccacgataaa aatatcttta gataaaatca agaaccgtag gaactacagg gatatttggt
     3001 caataagagc caccgctatt agtaaaaaat aagctatcaa gtatgctctc atcccaagaa
     3061 ttgcctactt caatcgttaa aaaccgttag gtttagctaa gtgggggtag ttcactcaat
     3121 acttttatca ataatagagc gcaaaacttt ttctcttaat tcaactgaat caatattatt
     3181 gttttgttca taaccatgaa ctaatagatc acaaatataa agttgtgata tttttccagc
     3241 taaagatcca ccattaagaa attcttcaat ggctgtttgt aaaactaagt ctgcagactt
     3301 tcctataggt gaatgaatat agttagttat agcaataatt tttgcgccat tttttttagc
     3361 tattttcaat gaatcataag tatctttcgt tttcccagat aaagaaaaaa tgattactaa
     3421 atcattaact gttaataaag aagcgacttg ggcttgaaaa tgagggtcta gtacagcttt
     3481 tgcttgaact cctacgcgaa gaaacatatt ttctaaatca agactagtat ttccactaga
     3541 tcccactcca aatatatata tgttttttga ttgagtgatc attttaatgg cttcattcaa
     3601 tttttcttcg tctaaaagcc taatagtgga atagagagct tctgttaaac tattagcaat
     3661 ttcatcatag tactttacac tagtcggatg ttcttttttt tgactaaagt cttcctttgc
     3721 aatttcaatt tttaaatcag aaaaaccaga aaaaccaatt ttttgacaaa agcgaataat
     3781 agtagcatcg ccaacttttg tgtttttctt aatatcactc atcgtactat aaataatagt
     3841 tttcccagaa tttaaaataa aatcagcgac ttttttttca gacttcgtta aaaatggata
     3901 attttcttta attaaataga tataactcat acaaactcct ctacaatttc aacttttctc
     3961 cattatactc caaaataata aaaaaaactc ctaaatactc catttttatc tttactttta
     4021 tgaaagcgga tgctatattg tttttggagt tgttatccaa aaataataaa aaattggagt
     4081 gtttaggata atggataaaa agaggttttt agatcttatt tcaaaaggtt tgattgtttc
     4141 ctgtcaagca ttacctggtg aaccatttta caaagaggaa gaaagtttaa tgccttattt
     4201 tgctttggct gctcaaaggg ctggagcagt tggtatacgt gcaaattctg ttcgagatat
     4261 tattgaaatt agaaagtgtg tatcattacc aatgattgga attattaaaa gagattatcc
     4321 accagaatct ccattcatta ctgccactat gagagaagta gatgaattag tagaaaccgg
     4381 tgttgaggta atcgctcttg attgcactct tagaaatcga catgatggac tatctataaa
     4441 ttcttttatt actaaaataa aagaaaaata tcctcatcag ttatttatgg cagatatttc
     4501 tacatttgaa gaaggcaaaa atgcatataa agcaggaata gattttgtag gaactacttt
     4561 aagtggatat actgaggaaa gtaaaaaaca agatgggcca gatatagatt tgattaaaaa
     4621 attggtagaa gaagggattt gtgtaattgc tgagggaagg attcatactc cagaacaagc
     4681 aaaagagata aaaaaaatag gagttgcagg tattgttgtg ggtggtgcta ttactcgacc
     4741 acaggaaatt gcatcaagat ttgttaaagc attaagttag ggggagaaat aaaatgttta
     4801 aaaaattttc acaattagga cgcgctttca tgttaccaat tgctatatta ccagtagccg
     4861 gattactatt gggactggga ggagcgttaa caaatgagag tgctataaat gcttatccat
     4921 ttttagatca accgtggttg catacaattt taagtattat gagttatgct ggaaatgcag
     4981 tttttgcaaa cctagcacta atttttgcaa ttggtattgc tgtaggactt gcaaatggag
     5041 ataaaggaac agctggttta gctggtggag tagcttatct agtatatact gcaactatta
     5101 gtgggtttct tgaacttttt tcagcaaaag atgcaacact agatacaggt gtagtgggat
     5161 caattgttgt tggtggtact gttgcatttt tacacaatcg ttatagaaaa attgaattac
     5221 cacaattctt aggttttttt ggaggatcaa gatttattcc gattgtttct agtttagctg
     5281 caatcattat tggttctttc ttttatttaa tttggccacc aattcaaaat ggtttagtag
     5341 ttgctggtga acaaattgcc caaatgggta gtttaggaac ttttttatat ggttttttat
     5401 tgcgtttaac aggtgctgtt ggactacacc acaccattta ccctttgttc tggtatacat
     5461 ctttaggtgg taccgaaact gtagctggat caacaattgc tggagcccaa aatattttct
     5521 ttgcccaact agctgatcca aaccacactg gtctgtttac ttatggtact agattttttg
     5581 caggaagatt tgcaacaatg atgtttggat taccagcagc atgttatgca atgtatcgtg
     5641 caattcctaa gaaaaatcgt aaaaagaatg gtgggcttta ttttagcggg gcccttacat
     5701 catttttaac tggaattact gaaccagttg aatatatgtt tttatttgtt gctccttggc
     5761 tttatgtgat tcatgcattc ttagatggat tatcttttta ttttgctgat atcttaaata
     5821 ttcgtgtagg gaattccttt tcaggtggtt tgatcgactt tttattattc ggtgtacttc
     5881 aagggaatga caaaactaat tggttaaaat taattccttt tggtattgca tgggcattta
     5941 tatatttctt tgtttttaca ttctttatca aaaaatttaa ggtagctatt cctggaatgg
     6001 aagaagaatc agaagttcat tctgaaaaag taataaacaa aaatacatca ttacatgaag
     6061 agtctcttat cattattgaa gctcttggtg gaaaagaaaa tattgagtct gttgaagctt
     6121 gtgcaactcg tttgcgtgtt gctgttacga atggggagat tattcaaaaa caaacaataa
     6181 aagacactgg tgcaactgct gtcttcgaag tgaagggtgg catccaagct gtttttggag
     6241 ggaaagctga cttattaagt caagaaatca atcaaatatt aggaaaagat aattaggagg
     6301 tttttaatat gtttgaaatt ttcaaaaaga aaaaacaaga aactttttat gcaccttgtt
     6361 ccggaaaaat catttccatc acagaagtaa atgatcctgt cttttcacaa aaattactag
     6421 gtgatggttt tgccgtcata cctgatggtt caaaaattta tgctccattg gctggtcgag
     6481 taacaaatat atttcctact aaacatgcta ttaatataaa aagcaactca ggcattgatt
     6541 atttgattca tattggaatt gatacagttg aattacaagg agagcctttt tcgatttgtg
     6601 ttcaagaaaa tgatgaggtt actcctgaaa cctcgttggt tgatgtggat tttgacaaaa
     6661 taataaaatc tggtaaagat acttctgtta tagttgtttt tccggagaaa aatcagttca
     6721 atgatttaat aatagataat ggtcgaattg ctcatgggaa ttcatgtgga aaaatcactt
     6781 tttaaaaaag tgtatataaa aagctataaa ataagctaaa taggatattt gtcaaatgaa
     6841 gttggtgaac agaaagaact gttttctttc tgttcatttt tttattttat tagtaatgat
     6901 tccccatgcc aaatcatgat ccgtaattta aagttataaa agcttcgaaa tccattggca
     6961 tttcgttgga ataccttgat atgattattc aaatataaaa tatagagaga agagagagag
     7021 ggaagatatt tataaagggc aaagttatgt ttactcaact taggaaatag aaatagatca
     7081 atttatattc tcttgtcaat cgaatatgaa ccttagcact atataccaaa tatagtaaaa
     7141 tgctgaaaga tgt
//
LOCUS       DBBGSP010000100         7126 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000100 DBBGSP010000000
VERSION     DBBGSP010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.100"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..507
                     /locus_tag="ACIZE9_002911"
     CDS             <1..507
                     /locus_tag="ACIZE9_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094712.1"
                     /translation="PEIPHKVFKDIQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDF
                     EDYRDIEVKPDPKKVGRKIRSIRKKLGLTMQEFGYEVSNSPRSTVSTWEHGGNLPNKA
                     KLKKIADIANCSVEDLLFDEGFISEKSQVKLINELKEENSKLKEKIKYYECLFDGIES
                     LLNSRKNS"
     gene            547..1158
                     /locus_tag="ACIZE9_002912"
     CDS             547..1158
                     /locus_tag="ACIZE9_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6094713.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFRKIGVEKVFAEKKSGRNTVERP
                     EFNKMLSFVREGDTLVFESLERLGRNSDEILETVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVINIFSWTAQNEREEIKRKQKQGIAIAKKKGVYKGKPYEYSSTAKNPQ
                     KRFIYNEIVRMLGEGVPIKRIAEKTGTNRNLVYRIKKRISESD"
     gene            1602..1751
                     /locus_tag="ACIZE9_002913"
     CDS             1602..1751
                     /locus_tag="ACIZE9_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094714.1"
                     /translation="MKLEIKEVVCDWGIYVDGETYPFMIFNSKANAQEIMRIMELDNK
                     HERFD"
     gene            2406..2969
                     /locus_tag="ACIZE9_002914"
     CDS             2406..2969
                     /locus_tag="ACIZE9_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094715.1"
                     /translation="MTAIYKALKNSNVSEYVKSRVLNNNLDYILENGVADLISKLSDP
                     IDIDHLVVWQDGTLEVSIYGEFYSRNKVTTFKNSISGREDLKGINKNSKFYRTNKELL
                     EKISKRVFELVNPFSKKRSKELFGIFYDGFSAKSNVEKFFYFNDSAYIAVKDSKRIPE
                     ATLEYLEPIKLSVFYSLYEKEIADEAV"
     gene            2980..3840
                     /locus_tag="ACIZE9_002915"
     CDS             2980..3840
                     /locus_tag="ACIZE9_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraA"
                     /protein_id="HGC6094716.1"
                     /translation="MSKKIGKESLSLGLKKEIVKFKSMYREPEFRLIFQLDIVRGLKI
                     SFSCLGYLVWLFIARVGWSNAYSFYKLFAGTDRLKESLEVKEALNILGSLAFSLFIFA
                     LFILQVGKIMMSTNDNYINYLKPFQKGIKIICRQGTVLFLLSLYEHEIHFQNYYNTTT
                     KLGAFLLLYLVSNIAEKMLFKHIVKQVFSDIQKESYCLKTPYGNLKNVELFLFKMDSK
                     WDKYIYRSKEVFLTGSYNKTLQESLYDTGAIFNNEPMVLKDFFGDYELVWNPKQLSEQ
                     GAENEFAEVH"
     gene            4234..4731
                     /gene="dfrG"
                     /locus_tag="ACIZE9_002916"
     CDS             4234..4731
                     /gene="dfrG"
                     /locus_tag="ACIZE9_002916"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HGC6094717.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4803..6755)
                     /locus_tag="ACIZE9_002917"
     CDS             complement(4803..6755)
                     /locus_tag="ACIZE9_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HGC6094718.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(6762..6998)
                     /locus_tag="ACIZE9_002918"
     CDS             complement(6762..6998)
                     /locus_tag="ACIZE9_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094719.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT         2535 a          977 c         1274 g         2340 t
ORIGIN      
        1 ccagaaatac ctcacaaagt ctttaaagac attcaagaaa gatatagtaa tacgttttcg
       61 ctaaataaag actatgagtt attgaatcct ataataaaaa atatatttac aaaatattac
      121 tcaaaagatt ttgaagatta tcgagacata gaagttaaac cagaccctaa aaaggtaggg
      181 agaaaaattc gttctattag aaaaaaatta ggacttacta tgcaggaatt tgggtacgag
      241 gtttctaatt ctcctagaag cactgtgtca acatgggaac atggtggtaa cttaccgaac
      301 aaagccaaac taaaaaaaat tgcagacatt gcgaattgta gtgtagaaga tttgcttttt
      361 gatgaaggct ttatttctga aaaatcccaa gttaaattga taaatgaact caaagaagaa
      421 aattcaaagc taaaagaaaa aataaaatac tatgaatgtt tatttgatgg tatagagagt
      481 ctgctgaact cacgaaaaaa ttcctagtta attaaactag agtaaaatta tttgtaggtg
      541 ttaaatatgt tagttggcta tgcacgagtc agttcagatg atcaaaattt ggaaagacag
      601 cttgaagaat ttagaaaaat tggtgtcgaa aaagtatttg ctgagaaaaa atctggacgt
      661 aacacagtag aacggccaga gttcaataaa atgttgtcat ttgtcagaga aggggatacg
      721 cttgtttttg agtcgcttga acgcttagga agaaattctg atgaaatact agaaacagta
      781 tcttttatag ataaaaatgg tatgggctta atggttttga atttaccaat tttagataca
      841 aaatttggtg atccaaactt agaaaaactt gttagaagct tagtaattaa cattttttct
      901 tggacggctc aaaatgagag ggaggaaatt aagagaaaac aaaaacaagg aatagcaatt
      961 gcgaagaaga aaggagtcta taaaggaaaa ccctacgaat attcttctac tgcaaagaat
     1021 ccacaaaaga ggtttatcta taatgaaata gtaagaatgc ttggagaagg tgttccgatt
     1081 aagcgaattg cagaaaaaac aggaacaaat agaaatttag tctatagaat aaagaaaaga
     1141 ataagtgaat ctgattgatt ttaagttctt tgagaaatca atgttacgag agaaggattc
     1201 taagcctgtt tcaaactttt aaggtgtaca attatacaaa gaagcttcta aacaaaagaa
     1261 ttaattttgt ggcagtcaag taacgacaga aatagaaaag aaagaggcta tgcgagagtg
     1321 aatcaacaag ttaattgggt taatgatttt gaaaaagaat ttcgactgaa attttttgga
     1381 aatcctacag cagaaagtac agaagaaaaa aattatgact ggtcagaatt ttaggttgca
     1441 tattcgattc aataagtgtt gaagataata gttctcttac gccacagtat acaacgttag
     1501 aatatgacga aaacagattc aatacatttc cttgcaatac cattcaagaa tcaattgata
     1561 agcatgagtg ataattgatt atctacagga aggtgttttt tatgaaacta gagatcaaag
     1621 aagttgtctg cgattgggga atttatgtag acggagaaac atatccattt atgattttta
     1681 atagtaaagc aaatgcacaa gagataatgc gtatcatgga gttggataat aagcacgaaa
     1741 gatttgatta agtaaaaaaa atggagaatg aatgtgaagc agtggaatac caaaaaacat
     1801 gcgccaataa taagtatatt ttaggtgcaa tgggattagg taaatcagct tctattaaac
     1861 aggtctacga agaatcacag gagaattgcg tatatgaaaa ttcgaattaa agagtgagaa
     1921 tatgtgggag ctaatttatt tagttttata cttaatagga aaatcaactg aatttgtata
     1981 taacaataag gtaatattta tattgttctt aatagtttgt attatcgtat ttgatgtcta
     2041 tgatttacta attcataaga atgaaaatag taatattggt agaattataa tcacaaactt
     2101 aatagtaatt actattggga ttacaacatt aacaaataaa gctttaatat caagtatgat
     2161 tttaatagtg tttgatttta ttatcattta tagtttgctg tttttaataa agaaagtaac
     2221 tgaatattta aatcgttagg cacgaaataa attttaattg aggttgaatt atagcggtaa
     2281 atcatacaaa atagaaatgt agtcttgtta agcgtcttga ctatctaatt ttgaatgagg
     2341 agggttgtat atagaaaaag ggtagttaaa ttcgtagatc aaaaggctac gaaggagaat
     2401 aaagaatgac agctatttat aaagcactaa aaaattctaa cgtatcagag tacgttaagt
     2461 cgagagtatt aaataataat ttagattaca ttttagaaaa tggtgttgct gatttaatca
     2521 gtaaattaag tgatcctata gatatagatc atttggtggt atggcaagat ggtactttag
     2581 aagtatcaat atatggagaa ttttatagta gaaataaagt aactacattc aaaaatagta
     2641 ttagtggtcg agaagattta aaaggaatca ataaaaatag taaattctat agaacaaata
     2701 aagaattgct agaaaaaatt tcaaagcgtg tttttgaatt ggtgaatcca ttttcaaaaa
     2761 aacgtagtaa agaacttttt ggaatttttt atgatggttt tagtgcaaaa agtaatgtag
     2821 aaaaattttt ttattttaat gattcagctt atattgcggt taaagacagt aaaagaatcc
     2881 ctgaagcaac tttagaatat ttagagccaa ttaaattgtc tgttttttat tcactttatg
     2941 agaaagaaat cgctgatgaa gcggtttaag gggagtaaaa tgagtaaaaa aataggcaaa
     3001 gagtcattat cgctcggatt gaaaaaagaa attgttaaat ttaaaagtat gtatagagag
     3061 ccggaattta gactcatttt tcaattagat atagtgagag ggctgaaaat tagttttagt
     3121 tgtttaggtt atctggtctg gctattcatt gctagagtag gatggagcaa tgcttatagc
     3181 ttttataaac tgttcgccgg aactgatcga ttaaaagaat cattagaggt gaaagaagcc
     3241 ttaaatattt taggaagtct tgctttcagc ctgtttattt ttgctttatt tatcttacaa
     3301 gtaggaaaaa taatgatgtc aacaaatgac aattatatta attatttgaa gccttttcaa
     3361 aaaggaataa aaatcatttg tagacagggc acagttttat ttctacttag cctgtatgag
     3421 catgaaattc attttcaaaa ttattataat acgacaacta aacttggtgc atttttactc
     3481 ctatatttag ttagtaatat agctgaaaaa atgctgttta aacatattgt aaagcaagtc
     3541 ttttctgata ttcaaaagga aagctattgt ttaaaaacac cttatggaaa tttaaaaaat
     3601 gttgagctgt ttttatttaa aatggatagt aagtgggata aatatatcta tagaagtaaa
     3661 gaagtatttt taactggtag ttataacaaa actcttcagg agagcctgta cgacacagga
     3721 gcaatattta ataatgaacc tatggttttg aaagatttct ttggagatta tgaactagtt
     3781 tggaatccaa aacagcttag tgaacagggg gcagaaaatg aatttgctga agttcactaa
     3841 catagtgtac agaaaaacat tatctgaaag aagaacgcct tcaaaagaaa gtacaagaac
     3901 gattgggccg tacagaagac taacgaaaga tcgtaaaaaa aaggaaagac aatgaaaatt
     3961 aagtagttca gttttggagt acaaaatgac aaaatgtact tcaaaatgga ctactttttt
     4021 cattttaact tacataccaa attacataca aaatgattta taaaatgcaa ttgaaaatga
     4081 taattgaatg aaaatttgtg attttgtggt attatgataa tataacttat agaaaaaatt
     4141 gcttattcaa ctaacgggca ggataatgag aaaaggtttt ttgatagaaa taagaaatta
     4201 gatggtaaat tagttaaaaa ggctgtgtta taaatgaaag tttctttgat tgctgcgatg
     4261 gataagaata gagtgattgg caaagagaat gacattcctt ggaggattcc caaggactgg
     4321 gaatatgtta aaaatactac aaagggacat ccgataatat taggtaggaa gaaccttgaa
     4381 tcaatcggaa gagccttacc tgacagaaga aatattattc tgacgagaga taaggggttt
     4441 acctttaatg gttgtgaaat tgttcattca atagaagatg tttttgagtt atgtaaaaac
     4501 gaagaagaaa tttttatttt cggaggagaa cagatttata atttgttttt cccttatgtt
     4561 gagaaaatgt acatcacaaa aatacatcat gaattcgaag gagatacttt ttttccagaa
     4621 gtgaattatg aggaatggaa tgaggtattt gcccaaaaag ggataaagaa tgataaaaat
     4681 ccgtataact actattttca tgtatatgaa agaaaaaact tattgagtta acgggtgcgt
     4741 taattgaaga agaacagtaa agataaagca caagagcttg ggattactcc aagctctttt
     4801 tgtcatttga aataaattat atctttccaa tcaaattgtt tatctgtaat ccctaatctt
     4861 tgagcaggtg tcaaaacctt tttatccgct gatttaaaag ggcgacaaaa gttgtagtaa
     4921 gttcttagaa ttgtaatcgc aaattgagca tacttcggat tgaagttagc gtaaatatag
     4981 ctcttcttat caccacgagc tgttgttaat ggtctttcaa gagatgatat ataacgtctt
     5041 atctgttgaa taaagctatt ggtcgaatgg tcattaacat ttaatagcat ctttgcgatt
     5101 tcgtttggtt ccagagcaga taaatccgtt ctacaatcaa ctgaataaaa tcctttatcc
     5161 ttagtggcta atggatgttt gatagggtta tcggcatatt tgcgatatct ttctccatct
     5221 ttactaatag cctcttcgtg gaattgatga cttgttagta attcagttag ataatgagat
     5281 gccaaagtcc gtagaaactt tgttttgaat cctctgatat ctccccaatc gagcagttct
     5341 gcttttgctt gtccgaattc ttttaagcat tgttttctgc ttttcgtctt gttaacttgg
     5401 caaataaaat gatgtgcatc gctcaacctt aattctttcg tgaatactct ataaaaggcg
     5461 tttctaatag agaagtcatc atcactaatc attcgccatt cgtcggcatt aaccatttgt
     5521 ttaattaacc aatagtgagc agttgtagta taaggagcat caacatttaa accatcgaca
     5581 aatctactcc tattagtaat tttccctaat tcgtgaagat aagcattcct attttcgcta
     5641 tcgttagcgg atggttcttg tggataataa gaccaatcta acctatcatt tttacgacta
     5701 aaagtattga gatggtcttc tttgaatttt cttgtatctt catttaattc atccattgaa
     5761 atattccaat cataggcaac atcagaacgg aacacatatc ttgataagac ctcagcagat
     5821 acaactatat acgtttgcat attaaggtct tcaaaccccg tatatttctt tgaaccttgt
     5881 cctttcttac ggacgttatt taggtagtag tgcatcttgt ccgtattaag ccacatctcg
     5941 ttaaatttct ttgtttgaag gggttgtgtc tcatatcgtt ctaaaaactc caaacaacgc
     6001 ctatacagcc actccagctt atgatagtag gttccaactc caattcctaa aatatcacaa
     6061 gtacgactga ctgaaaccct tccaacaacc atcttagcga acattggaag aatggtgttc
     6121 ttttgttggt gataagtagt ggtttcttct ctttttggta gaacattagt gaacttctta
     6181 cacgccttac attgatagcg ttgagatttg cccctacttt tccccctttt gtaaaattgc
     6241 ttcggctcat tgaatggggt tgattcttct tccgagcagc cttctttatg aaattgataa
     6301 tctggctcaa catcttggat gctattgatt tctataaggc gtttaatttc ttcaacaaca
     6361 gaccaattag ataaaggggt tactgtacag ttttgcgata cacctctgcc aataggattg
     6421 tcattgcagt acataccttt atgaccttta tctttggaac taccagtcat tttatatcga
     6481 cttggtttcc cttttacatc tttgaatttg tgctgttctt tcccaaaatt acaacaaaac
     6541 ggattgatgc agtaattata ttgaatggga tattcagaac cgttccattt aaaagacgtt
     6601 ggcaagaaca acattttgtt ataccttgtt gcaaatcgtt ttggagttaa taaatcatat
     6661 tgtttagccc tatcttttaa ttcttcgttt gaaatcggaa ttttaacatc tacaatttca
     6721 tcttccttcg tggctaatct tttaagcttg gtcattgtct atcaacccac tctatctttg
     6781 atacccattt tttcaacaat ccgcttatta cttcgcttgt tggcaatcca ttcaataaac
     6841 ttcttatcgt ctaaaatgtt caataagaat tcatccactg cttcgctttc agtacgctct
     6901 gcatattcag cgtattgctt aactatcacc cttacttgct ctgatatttc ccaatccaca
     6961 gacttagcgt tcttattttt tggctcaaga aattgcatag gaaaatgcac ccctttttgc
     7021 ttagtaaatt gtaaccattt taacacacca atttgcattc ctacaataat tatttcacgt
     7081 tcgcattttt atatacattt taacttacat tttgtggtgt aaatta
//
LOCUS       DBBGSP010000101         6684 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000101 DBBGSP010000000
VERSION     DBBGSP010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6684
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.102"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..615
                     /locus_tag="ACIZE9_002919"
     CDS             <1..615
                     /locus_tag="ACIZE9_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HGC6094720.1"
                     /translation="FVFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVG
                     KYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGT
                     GVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPF
                     ILALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            612..1385
                     /locus_tag="ACIZE9_002920"
     CDS             612..1385
                     /locus_tag="ACIZE9_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HGC6094721.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1382..1780
                     /locus_tag="ACIZE9_002921"
     CDS             1382..1780
                     /locus_tag="ACIZE9_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HGC6094722.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1965..2636
                     /locus_tag="ACIZE9_002922"
     CDS             1965..2636
                     /locus_tag="ACIZE9_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094723.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2695..3135
                     /locus_tag="ACIZE9_002923"
     CDS             2695..3135
                     /locus_tag="ACIZE9_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094724.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3147..3815
                     /locus_tag="ACIZE9_002924"
     CDS             3147..3815
                     /locus_tag="ACIZE9_002924"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HGC6094725.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3879..4502
                     /locus_tag="ACIZE9_002925"
     CDS             3879..4502
                     /locus_tag="ACIZE9_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HGC6094726.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4558..4944
                     /locus_tag="ACIZE9_002926"
     CDS             4558..4944
                     /locus_tag="ACIZE9_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGC6094727.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5157..6548
                     /locus_tag="ACIZE9_002927"
     CDS             5157..6548
                     /locus_tag="ACIZE9_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HGC6094728.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         2128 a         1081 c         1488 g         1987 t
ORIGIN      
        1 tttgtttttg caccgttaga aggagaagac ctcgcttcat ttctggttgg tgcggcaatc
       61 atgatgatcg gaatgacgct ctttttgttt ggagcagatt attctatgat ggaagtcgga
      121 gatctagtag ggaaatatat gatcaaaaag aaaagtttga ccgttttggt cagtttggga
      181 tttgctatcg ggatcgtgat cacgattgct gaaccttccg tgcaagtttt gggacaacaa
      241 gtatatgata tatctgacgg agagattggc agagtgttgc tgattgggat cgtcagcgtc
      301 ggcactggag tatttctagc ctttgcgctg cttcgggtcg tattcaagct atcctattat
      361 caattgatgg ctataggcta cataggcgtt ttgatcgcct catttttcac cagttccgaa
      421 tttatgccga ttgcttttga ttcgggggga gtgactactg gtccagtaac tgttccattt
      481 atcttggccc ttgccggagg gatgactagt atgatcaaac aaaagaaaaa tgaaaatgac
      541 agttttggaa tggtcggtat tgcttcgtta gggccgattc ttgccgtgat gattttgggg
      601 gtgatcttcc aatgagtttc tggcagcaag tgatagatgg aatcgaaatc gttaccatgg
      661 aagtcatttt ggcagtggca cctatcgtaa tcctatttgt tttaatgaat atcattagtt
      721 ttcgtatgcg caaaaagcgt ttctttgaca ttatgaaagg tttcttgata acgactattg
      781 ggttgatcct tttcctgcac ggagtcaata tggcttatgt accggtagga cagcatttag
      841 gcagtgctat tgcgggattg ccttacaatt atatactggt tccccttggc tttttaatgg
      901 ggttcttagt agggtttgct gagccggcga ttcatgtaat gatcaaacag gttgaagaat
      961 tgagcgaggg gagaatccga tcgaaaatca tgctgatggt aatttcaatt gggatcggcg
     1021 cagcagtagg attgtctatg tggcgtttgc tcgtcggatt ctctctttat tatttcttga
     1081 tcccaggata cgggctagca tttattttag gacgaaaagt ggacaagatc tttttagcaa
     1141 tggcttttga taacggtgga gtagcaacgg gcccgatgtg ttcgacattt attttatcaa
     1201 tgagcgtggc aatcgctgca caaattgaag gaagagatcc gatcattgac gggtttggtg
     1261 tggttgcaat gattgcattg acaccaatat tatccacttt agtactagga tatatttata
     1321 aacgaaaaga tgaaaaagac agaatcgaaa aagaaagatt gcaaaaattg ggggaaagca
     1381 aatgaaagat cttgtagcat tgaatcttca catgattgtg acgatcgttg acggaggaat
     1441 gggcgaagat gttatcgact tttcaaaaga agcaggtgca gcaggcggaa cgatcttaca
     1501 tggaagaggt tctggtgtac atgattcagg gaaattttta ggtttggaca tttcgccaga
     1561 aaaagatatt gtgttgacat tagtacccga tagtttgacg aataaagtaa tggatgcgat
     1621 tggtcaaggc atcaacatcg atattccagg taatggtatt tgttttagta ttgatgtaga
     1681 caaagtcatt ggtatcacta agattcatca atatcgagaa attatcggaa tgcaagaact
     1741 tttagatgaa aataacgata gagaaaagtc tgaatcatag acaagcgttt gaagaggaaa
     1801 taaacacaaa caagaaggcg gatgagcgtt atttccgctt ttttgtttgt atttttctcg
     1861 tgaatactta tgaaatagta aatttttatg aaattctact ctaagcatca gactttcttt
     1921 tcaaaatatg ctattttaaa aatgatgaaa aaagggggag aaaaatgaat tttttagttg
     1981 ttttaaaaga tactctgatt gagcgattta catttctata tgttcaattg caggaaaata
     2041 aaacattgct gcatttttca ccagagttcc atctagaggg gctaacatta ggagaaatct
     2101 atcaagcaga agggctgtcg gctgttttgc acttttttaa ggtagaattg gaattaccag
     2161 taaaagatta tatcgagctt tctcttgaat cttgggatcg agcagtggtt gaactgtttc
     2221 cagaaggttt aatgatcgat acaaacgatg ggaagatcca tctgactgca gcagaactgc
     2281 aaaaacaaat gcgttatcaa atagatgacg aaaattcttt ttctattttt agacgtcagc
     2341 aaaagattct aaaaagcttt ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga
     2401 cacagctgtt gaaaaaatat ccaggtctgc ttcacacgtc tattcaattt cctcaattga
     2461 ttacgatgat ccatcgtttt atacgtatgc aacagctacc atctaagaag ctgtttcttc
     2521 cattgacgga cacatttcga gtagtcaaca gagaagataa aaagaaagtg attgtgattg
     2581 actttaccag aaatcggaat gtccttcacc aagttgcaat ggaaaaggcc aattaaggct
     2641 ttttcttttt ggattttttt gtcataataa atattagatg atggaggaga taatatgatg
     2701 caaacatggt tagaaaggct aatacgattt cagcagaact atcacaaact tatgcaggga
     2761 agatatgcga aatttgatca gttgaatcgc ggtctattga tcgctgcgct tgtctttagt
     2821 ttgctaagtc gttggttgcc ctatagaatc ggacaattgt tgttcatcgt ctttttcgga
     2881 tggatgatat ttcgtttcct atcaaaaaaa atctacccca gactaaatga gaatcaacgt
     2941 tatttgaaat atcttgatag agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa
     3001 gtcaaaatgg atcgaaaaag ttatactttt tttgagtgcc cgaattgtca tcaaaagcag
     3061 cgtgcaccta aaggaaaagg acgaatacgt gtgacatgca aaacatgtgg tataaaattc
     3121 gaaacgaatg tttaagggag aaaagaatga aattagtatt attacgtcat ggcgaaagcg
     3181 aagcaaattt tgaaaattac tggacaggat ggctagatgt cgccttaaca gaaaaaggaa
     3241 aagaacaagc agcagttgcc ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg
     3301 tttatacctc tgttttgaaa cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg
     3361 gtcagttatg gcttcctata ataaaaacat ggcgtctaaa tgaacggcat tatggggatc
     3421 ttgtgggtaa aaacaaagat aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat
     3481 ggcgcagagg atatacggaa gttccgccgt taaccgcaga aaatagattt gaccgcagat
     3541 atgatcactt ggatccgcat ttgatcccat acggagaaag tctggaaatg acagtgaatc
     3601 ggatcattcc cttatggcaa gatcatctag caccaaaact aaaagatcgg caagatttac
     3661 tagttgtggg tcatggtaat agcatccgag cactgacaaa atatttagaa gatgttcctg
     3721 aagatcaaat ggatacgatc gatatcccaa atgcacaacc aatccagtat acattagcag
     3781 atgatttgac aattctggac aaaaaaatac tttaaagaac acctttatct aaaagtgaga
     3841 gatagaaaaa agaagcaaag gaatggaaca aaaggaacat gaaaaattat atatgggact
     3901 ttgatggtac attgtttgat acgtatcccg caatggtaga tggtgcatgg caagcactaa
     3961 aagattttgg tatcagtatg gacaaaaaag aaatctactt caaaatgaaa aagtattcta
     4021 ctagttattt gatcaatgaa tcaaacttga atgccagaga gtttaatgaa ttatttcacc
     4081 gatatgaaaa agaaagtacg gaagtttccc gtccatttcc agaaacgaaa caagtactgg
     4141 aaatgctaaa agacaacggc ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa
     4201 catggggcct gttaaaagaa catcgattgg cacatctgat tgaggaagta gtagggatcg
     4261 atcaggactt tcctcgtaaa cctgatccag catctttaaa ttatttgatc gatacttttc
     4321 atttagaaag aacagacacg atgatgatcg gcgatcgtcg tttagatatc gaagcaggga
     4381 aaaatgcagg agtcgctact tgtctttacg acatcgatca ttttctgggt gagatcccgg
     4441 cagattatgt ggtaggaaat ctgaatgaaa tccttacctt gcagagcatc attaaaaagt
     4501 agtatcccct ttcaaaggag atatgttata attttcataa aggagtgata aaattatatg
     4561 gaaatcagaa gacaaaaaga agttgtagaa gcatttcatt atgatatgag attgccgaac
     4621 caagaagtag aaacagattt gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac
     4681 tatccgaaag aacatagcat cgtaggagca cgcttagagt tccgtttagt gtttgataca
     4741 tatgttttat ctggaagtgt gagtcagatc aatcatatcc tcaatcggaa aattgaaggt
     4801 caaaatgatg tcacacaaga agaagtggac gagctagtag caccgttatt cgatatcgta
     4861 cgccgaatgt cttatgaggt gacagagatc gccttagatc agcctggggt aaaattgaat
     4921 tttcaatcag aaaaacaaga atagacagta aaaacatacc tgcgatagat taaagctatc
     4981 acaggtatgt ttttttatta ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg
     5041 tctaaaatat aaaagtcact gaaaaaaatt ttttcaggag gatggttgaa gaatcattct
     5101 cgggaacctt tacttccttc gatggacttg tcattaataa tatgaggagg agaaaaatga
     5161 caacactcat cacagtttta gtggttctag tttttgcggc attattatat gtgttctatc
     5221 gtatgcaaaa gcgccataca aaattttcaa cacgcgtctt tacagcatta ggagttggta
     5281 tcgtctttgg cggtctgctt caattgatct ttggtgtaga cgacaaagtc gttactcaat
     5341 caatggaatg gatcgggatt gtaggtcaag gatatgtatc attcttgcaa atgctagtta
     5401 tgcctttagt gtttatttcg atcattggtg cattcacaaa aatgaaagtt tctgaaaagc
     5461 tagggaaaat tagtgcgact gtattgactt ctttacttgg aacaacagct attgcagcat
     5521 tgatcggaat tggttcaaca atgctgttcg gactccaagg agctaaattc acacaaggag
     5581 ctgcagaaac agcacgaatc tctgaactgg caacacgtca ggaaacagtt gaaaacttat
     5641 cgattccaca gcagatttta tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta
     5701 gtcgtgcaac aagtacgatt ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc
     5761 taggcgtgaa aagaaaagcg ccaaaagaag cagcattctt ttcagattta gtcgacagtc
     5821 tgtataaaat cattatgcgg atcgtgacgc ttgttttgcg tttgacacct tatggagtat
     5881 ttgctttgat gacaaacgtt ttggcaacaa gtgattttgc agctatcgtc aatttaggta
     5941 aatttgtcgt tgcttcttac gtagcattgc ttgctgtttt gattgtccac tcactgattt
     6001 tgattggtgc aaaagtcaat ccaatcaact atttcaaaaa agcctttccg gtattgagct
     6061 ttgcgtttac ttcacgttca agtgctggag ctttgccatt gaatatcgag actcagacaa
     6121 aagctttagg agtagatgat gcaacagcta atttctcagc aagttttggt ttgtctattg
     6181 gacaaaacgg ctgtgctggc gtttatccag ctatgttggc aacgatcgtc gcaccagcag
     6241 ctggagtgaa tgtctttagt ttggaattta ttttgatgct tgtggcaatt gtaacaatca
     6301 gttcttttgg tgtagctgga gtcggtgggg gcgcaacatt tgcttcactg atcgttttag
     6361 gggcaatgaa cttgccagta gcaatcgttg ggttagttat ctctgttgaa ccattaatcg
     6421 atatggcacg tacagcagta aacgtcagcg gtagcatggt agctggtatc gtgacaagtg
     6481 cacgcatcaa agatttagat cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga
     6541 atgcatagtc aaaaagaggt tgtgatagaa gtggtcagct ttaagaaata agaagaagtt
     6601 tcctaaaaat agtttctcaa atttttgtga aatttcggct tatttccgag aagctacttc
     6661 tgaaacaccg tgaataagag gttg
//
LOCUS       DBBGSP010000102         6589 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000102 DBBGSP010000000
VERSION     DBBGSP010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.103"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            46..903
                     /locus_tag="ACIZE9_002928"
     CDS             46..903
                     /locus_tag="ACIZE9_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HGC6094729.1"
                     /translation="MEEKLIKKDEIIMGLLVPRANTYTIPLTKRQLIAKRYQRITRAI
                     NREFWNSESDTAHSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQ
                     VIKNAFQEILPNSDIRADGQVVKINFHDGIKFEIVPAFNEKDYLGESKGFIYPDSNMG
                     GNWKATNPKKEQEAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEA
                     MGNWKFVENNSGGQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICL
                     EKVLKKIAL"
     gene            923..1483
                     /locus_tag="ACIZE9_002929"
     CDS             923..1483
                     /locus_tag="ACIZE9_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HGC6094730.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNKTHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            2391..3158
                     /locus_tag="ACIZE9_002930"
     CDS             2391..3158
                     /locus_tag="ACIZE9_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HGC6094731.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            3184..3729
                     /locus_tag="ACIZE9_002931"
     CDS             3184..3729
                     /locus_tag="ACIZE9_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094732.1"
                     /translation="MGERTQALITVKYGNSKTKVSVSIHYQWGYGRFMLMDVLNQGIY
                     LINKAYDLRDESREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            3730..4296
                     /locus_tag="ACIZE9_002932"
     CDS             3730..4296
                     /locus_tag="ACIZE9_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094733.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTIEGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMETENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGTDDCVAYYTTAE"
     gene            4311..4559
                     /locus_tag="ACIZE9_002933"
     CDS             4311..4559
                     /locus_tag="ACIZE9_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094734.1"
                     /translation="MEGMDFIDHEDLIDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDNTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            4578..4817
                     /locus_tag="ACIZE9_002934"
     CDS             4578..4817
                     /locus_tag="ACIZE9_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094735.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEELLRKAKQKGYPDKMLKQIGYYM
                     PEERIEKESCKVLFDSEQLLVLLTQNKLICQFENN"
     gene            4834..5418
                     /locus_tag="ACIZE9_002935"
     CDS             4834..5418
                     /locus_tag="ACIZE9_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094736.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEENMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEPELILERQRILFSEQDSKRLYGLYDLQLKGLKAQYV
                     ADSYDDMVEQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSKVES"
     gene            5525..5806
                     /locus_tag="ACIZE9_002936"
     CDS             5525..5806
                     /locus_tag="ACIZE9_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGC6094737.1"
                     /translation="MKVKNPKEKSRIQVGIDKDLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTMDMPVDVLDTDEKLEEWFNEA"
     gene            5796..6137
                     /locus_tag="ACIZE9_002937"
     CDS             5796..6137
                     /locus_tag="ACIZE9_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGC6094738.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     NKSDQIKRVYFPIAEWEKVGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSAIDTKKL
                     NRFIERLQRKV"
BASE COUNT         2487 a          852 c         1347 g         1903 t
ORIGIN      
        1 ttatcaataa attgcttgaa gtattatatt tagatatcat aatttatgga agaaaaatta
       61 attaaaaagg atgagattat aatggggtta ctggttccga gagctaatac ttatactata
      121 cctttaacga aacgccaatt aattgctaaa agatatcaaa ggattactag agccatcaat
      181 agagagtttt ggaattctga aagtgatact gctcacagtt tatacgtagg ttcttatggg
      241 agaggaacgg caattagtac tagtgatata gatataatag ttgaattacc gatggcagaa
      301 tttgacagat tcaaaaatta tttatcaaat ggaccgtcta agttattaca agttataaaa
      361 aacgcatttc aggaaatact accaaatagt gatattagag ctgatggaca agttgttaaa
      421 ataaatttcc atgatggaat caaatttgaa atagttccag cttttaatga aaaagattat
      481 ttgggtgagt caaaagggtt tatttatcca gattcaaaca tgggagggaa ctggaaagct
      541 acaaatccca aaaaagagca agaagccatg aaattaaaga atacaaaaag taataattta
      601 ttatatgcta cgtgtaaaca ttttcgacat gtacgagata cagaatttac gagttatcat
      661 ctttcaggaa tagtaattga cagtttcgta tatgaggcta tgggaaattg gaaattcgtt
      721 gaaaataaca gtgggggtca aaacattagt tctgtatctt atgagacagc tttattagaa
      781 tactataact cacataaagt tatgggcggt ttaaatttat actctcctgg aagcaatcaa
      841 tttgttaatt ctgatagtag tatcatatgt ttagaaaaag tattaaaaaa aatagcttta
      901 taaagtttta tggaggaaca acatgggaga cgaaaaaaag cgcttggaag ttcaattacg
      961 tgaagcatat ggacgagtaa cgtatactta caccactcat ttaaagcaag ccgataatat
     1021 tatttctgac aataaaattt taaggtgtct tcaaattggt ttgtcagccc ttactactgg
     1081 aggggtactt agtaccatta ttactgataa tagtgagtta acctttgttg ctggattatg
     1141 ttcaacaatt tctcttggat taaacttata ctttaagaat tttgatcttg ctgaagaagc
     1201 taaaaatcat caaattgttg ccgataaatt atggttgatc agagaagaat acgtaagctt
     1261 actaacagat ttaaatcgtt taagtgttga agatattgtg aaaaaaagag atcaattaat
     1321 gaacaaaact catgaagcat ataaaaatgc ccctaaaaca aatagtaaaa gctatgaatc
     1381 agctcagaaa gcattaaaat ctgaagaaga gcaatttttt acagaagagg aattggataa
     1441 gatgttacca gagcatctta gaaaaaagag ttctaaatat tgaactcttt ttttatgctt
     1501 aaaattttct tgtaattttt ctattcaatc aataaataat ctatatttaa gaagaaatat
     1561 gatgatagaa acatctccta aagccaccgc aagccgtcct agccattgcc cagtccgaca
     1621 tcgctagatt agtgcatctc tccaaaaaag ttttctaaag ccaccgcaag ccgtcctagc
     1681 cattgcctag tccgacatcg ctagattagt gcatctctcc ataaaagttt tctaaagcca
     1741 ccgcaagccg ttctaagcat agcttagccc gacattgcta gatatgctca tctcaccatg
     1801 aacgtttcct aaagccaccg caaaccgtcc tagccatcgc ctagtgccta gtccgatttt
     1861 gcttgatcgg ttccatttct gtttatttag tgggtcaaca ccgtaatctt aaatagccat
     1921 cgcctattta agattactag gtctgctttg aaggtaaaaa gtctttcatt cttcaagact
     1981 tttaggcttt caagctacgc ctgaaagcat tgaaattcat cgctctttat ttggttttgc
     2041 catttataat tccttacgcc cattatcttt ttcgcctgtc ataccttgtc agaagtgttt
     2101 agagcttatc tcatctttgg attaatacaa gtggcgtaaa tttttttcta aacgcaagcg
     2161 ttacgaaaat aatttactta aacacttgta ttaatccggc agataagaac gcattctaat
     2221 cactcccgac aaggcaagac aggcgaaaaa gataaataaa tgaacgaaag gaagaaacat
     2281 aaaatgcaaa accaaatagc gatgaagaaa aaaccacctc cctctaaaac aatccaaaca
     2341 aaaaagaatt ttgaaaaacc aaaaatcaaa aacagaaaga agcgttcaac atgagagata
     2401 gaattttaga agttaatcaa gaaatggtaa acaagttaac aaatatcagt gggaactatg
     2461 aaaagtacga tggtacttta cttgataatt atatttttca cgatacacaa aatatcagaa
     2521 ttggcagaag taaaccgaga gcgttcattc tcatcaaaga gaaatatttg aatgaatgga
     2581 atagcaccta tgaaatggtt atgactgata actttgaaaa ggtattggat ttcagaaatg
     2641 ctttgttggg ttctgatatg ggaaatagca gtcttgaatc tattgaagtt gaaaacaaga
     2701 ccgagaatga aggtgaagga ttgattaaga atgtcctgaa aatcgaacaa aaatatatca
     2761 gtgaagatag aagtttttat agagtcacaa gctcggttgg tctagcaaac tttgctacta
     2821 acttaattgg aaacaatgct agtgaatctt tgctagtgat gtgtctgaat acaaagaatg
     2881 aggtcattgc ttatagcgaa gttttcaaag gtggaattaa tcaatcagta gcgataccaa
     2941 gagagatttt tcaactagct ttgctaaaca attcagcaaa aatcgcagta tcacataatc
     3001 atccgagcgg atatgaattt ccaagtgaaa atgacaaaag ttttactacg aatttgaaaa
     3061 acgcaggaaa aacaattggt attgaattgt tagaccatat catcgtaaca agtaaaaaca
     3121 caagctatta ctcatttcaa gaaaatggtt ctttataaaa attagagaaa agaggaaaac
     3181 aagatgggcg aaagaacaca agcgttaatt acagtcaaat atggtaacag caaaacgaaa
     3241 gtaagcgtgt caattcatta tcagtgggga tatggtcgat tcatgttgat ggacgttttg
     3301 aatcaaggaa tatatttaat caataaagca tatgacttac gagatgaatc aagagaagaa
     3361 ttagcaaaag gaatctttga tagaagtaca ggagttatca attttgtcac ctatgaatct
     3421 ggagtgagtg cttatgatga aacagggttt ggtgggcgct atgaacctta tcaagaaacg
     3481 attgaagatg tgatgaagtt ttcagataac aatgatggct atgctcattt agagatggtg
     3541 ttcgatgaaa atggatttag tctagatgat aaaaccagat tgcgattgtt tgattttgag
     3601 ggtcaacaga taggactaaa caagttttgt gaaagcggaa aagagtttgc tacgaaagat
     3661 tttattaagg gatacagatt attgctagaa aattatggaa taaacctaga agaagagagc
     3721 gtgaaataag tgtttgaaaa aagaaaagac cagttcccta atttagaagc gaaaagtcaa
     3781 aaagtgattg atggtgaaat gattgaatta ttccaaaaaa gttatggaac catagaaact
     3841 accgcaagtt gcaaatacta ctttcaagga aagagaaaca cgtttaaagg ctttgccgat
     3901 tctgatgaag aattggcaaa gaaaatcatt gattggcttg tcagcagtga acacgtagca
     3961 agagaagata ccgttagaac aacgattgag ggtgaagtcc taacaggtac tagatgtgtt
     4021 tgttgtaatc atgaatttgt agaagatgaa ggttgctacc gaatcaatga atatggtgat
     4081 tttatttgcc agagttgcca cgagatagaa tttccaaccg aaagaagttg gtttgaatac
     4141 atgctacaag attatgagat ggaaacagaa aatggtgaag tagttttttg taccaaagag
     4201 gaattgagta agagaagcga tgatgaaatt gaagattggt gtgtgtggtt agtagggaca
     4261 gatgattgcg ttgcatatta cacaacagca gaataggagt gtgaatcagc atggaaggaa
     4321 tggattttat agatcatgaa gatttgattg attttggtta tacatggaaa ggaatggtag
     4381 gtattagcag aagtcttgct aatgcctttt acgaaagaaa ttatgcagtc tatgtccttt
     4441 atgatgacaa tacagaaagc cttgttgatg aagagtataa attggattta gagaatgttt
     4501 tatatgggat agaaaaagaa gatttagcaa aatatatttt ttcatggttg ggtcaataaa
     4561 cgaaagaggg tagcaacatg acaaaattca aaagtaaagg tatgcaatgg tgttcttatt
     4621 attatgttgg gaatgatgaa gagcttttga gaaaagccaa acaaaaaggt tatccagata
     4681 agatgttaaa acagattggc tattacatgc cagaagagag aatagaaaaa gaatcttgta
     4741 aggttctttt tgatagtgaa cagctattag ttttgttaac tcaaaataaa ttgatttgtc
     4801 aatttgaaaa taattaatat ggggtgaaga accatgaatg agaataagat ggtattaagt
     4861 gaatacgcaa gattgagaac cattaattgg ttgaatggta tgcaaagtag tggcgctttt
     4921 gatggatttg atgaggagaa tatggacttt gaaagtttat cgaatgagga tattagatat
     4981 tattttatcg aatggtattt tacagaacca gatgaagagg tggaagatga accagaatta
     5041 attttagaac gtcaaagaat tttattcagt gaacaagata gtaagaggtt gtatggttta
     5101 tatgacttac aactgaaagg attaaaagcg cagtatgttg ctgatagtta cgatgatatg
     5161 gtagaacagg gggcagatag ggttgtcact tattcagaag atgatgaaga ggaatgggaa
     5221 aactattcag atgatgagat atgctttaat gatgggtata tgcctattga aatcaccgaa
     5281 gaagaatatg ataaagtgtc ggatagcgat gagattggta tgtgtacggt tgtaagtgga
     5341 ttggatatag atgtccaaag agtagaggtt gcataccaga agatgaaaga acgtataaaa
     5401 agtaaagtag aatcttgatt tgattggatt gtttgcaaag tagctaatta agagtataat
     5461 ataatcataa atgtagttaa tggatataat aatgagtata ttatactcaa aagaggtgaa
     5521 cgaaatgaag gtaaaaaatc caaaagaaaa aagcagaatt caagtcggaa tagacaagga
     5581 tttaaaagaa aacgcagaaa tgatattgga agagctaggg ttaaatccaa caacagcaat
     5641 cacaatcctt tataagcaag tggtcgctag aggtgagttt ccagtagaga taaagctaag
     5701 cgaagaggaa aagcaaggaa tcagattgca acagctaact atggatatgc cagttgatgt
     5761 tctagataca gatgaaaagt tagaagagtg gttcaatgaa gcctaatgag atagtaacgg
     5821 tctatgttgc atttacagat aaaaatggtg gtaaaagaag acctattttg gtggttagtg
     5881 ataaagaaga tagagtagaa ttttttggaa tcacaagtca atatgagaat aaatcagacc
     5941 aaataaagag agtgtatttt cctattgcag aatgggaaaa agtaggtcta aagaagcaat
     6001 catggattga cgtagggtct ttaaaggcta ttcccaaaag ccgagagaac atatcattta
     6061 aaaaggttgg tatgctatca gctattgata cgaaaaagct aaataggttt atcgagagat
     6121 tacaaagaaa agtctaacaa ggcttttctt tttttgttta tatgtatatt aagatatacg
     6181 tttatataaa cgtatttatg tatattaaaa tacacgtaaa tatatacgtg attataaaaa
     6241 ttaagaaaat attaagtatt gttaaatagt gataattagt aatatacgaa ttataagata
     6301 cattttatat ttaatgtatg taaataaata aaatgactga cggatattga atagtaataa
     6361 ataacaataa ttcagacgga tacagtgagt gaagtagctt gctacgaacg aacaggcaga
     6421 atgaaacggt agtttcatta gagcaagtcg cttgcgacgt agcgttacca ctgatgtaac
     6481 tggcaagtta catagagaga gtttgcttgc aaacgaacgt tacccacttg aatagaaaac
     6541 aaaaataaca tattagtgaa ttttgaatag gagccacaac tcaaccaac
//
LOCUS       DBBGSP010000103         6347 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000103 DBBGSP010000000
VERSION     DBBGSP010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.104"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            290..1135
                     /locus_tag="ACIZE9_002938"
     CDS             290..1135
                     /locus_tag="ACIZE9_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6094739.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="ACIZE9_002939"
     CDS             1416..2636
                     /locus_tag="ACIZE9_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HGC6094740.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="ACIZE9_002940"
     CDS             2633..5353
                     /locus_tag="ACIZE9_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6094741.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="ACIZE9_002941"
     CDS             5337..6281
                     /locus_tag="ACIZE9_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGC6094742.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2363 a          983 c         1224 g         1777 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 tcgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgttttc
//
LOCUS       DBBGSP010000104         6286 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000104 DBBGSP010000000
VERSION     DBBGSP010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.105"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            190..690
                     /locus_tag="ACIZE9_002942"
     CDS             190..690
                     /locus_tag="ACIZE9_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HGC6094743.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            787..2634
                     /locus_tag="ACIZE9_002943"
     CDS             787..2634
                     /locus_tag="ACIZE9_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HGC6094744.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2637..3533
                     /locus_tag="ACIZE9_002944"
     CDS             2637..3533
                     /locus_tag="ACIZE9_002944"
                     /inference="COORDINATES: protein motif:HMM:NF024700.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6094745.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3583..3972
                     /locus_tag="ACIZE9_002945"
     CDS             3583..3972
                     /locus_tag="ACIZE9_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGC6094746.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3959..>6286
                     /locus_tag="ACIZE9_002946"
     CDS             3959..>6286
                     /locus_tag="ACIZE9_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6094747.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2118 a          933 c         1347 g         1888 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg gggcatggtt taccccaccc gtcgattttg atgaagtgaa agaacggatt
      301 ggattaaatg acgaatatga agagtacgca attcatgatt atgaactgcc ttttgagatt
      361 gatgagtata caccaattga ggaaattaat cggttgtgtg gtttagcgga agagcttaaa
      421 ggaacgccaa ttggtgaggt cgcttcagag attcaacatg ccttcttcaa ttctttcgag
      481 gaaatggtag agcatgtgga tgatatcatc tattatcccg attgtaatga catgagtgat
      541 gtagcgtatt acttgattgt agaagctggt gatttaggcg aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtcga gacttggaga ttggcgggaa ttatttggtt
      661 acgagtcgag gggtttttga actaatgtaa atcatttgtt agaattgacc agaaatttct
      721 atcgtacttt tacttttcta tttgatatac tgaaatagaa aatatttgtt gataggggtg
      781 ttactaatgg ttggcaataa gtggtacaaa tgtgatcttc atattcattc aactgcgagt
      841 cagtgctttc aggataaaaa ggttactgct aaggaatggg tagaagaatg tttaaacaaa
      901 ggactcgatt gtgttgcatt aactgatcac aatacagggg aaaatattga tgaatataag
      961 aaagtggcta tcgaaaatgg cttagatttt tttcctggag tggaattaac gtgtggagaa
     1021 aatggaactc atttactagt cctatttgat aaaagtgcat gtacaaatga tatctctgat
     1081 ttcttaacca agatgggtat aaaaagagag gattgggcca gcgctgcagc ttgctcaatg
     1141 aaatcagttt tagaagttat tgattttgct gagcacgagg gcttgctcgt tattcctgca
     1201 catatagatg agtttaatgg aatttcttca gcaaaatttg gaaatctagg aaagatattt
     1261 gaatcagaaa atatatatgc agtacagacg gttcaaaaag aattttttga aaatcgctca
     1321 caaatgattc cctcatctaa gcgtgacact atctatgata gtgtgaatgc cagatatgat
     1381 ggtagagttg gaaaagatac tttggaatct tggtataaat cagttgttga ggcagaaaaa
     1441 aataatatga catttcttag cttttctgat aacccacact cgaaaggaaa ttcaaaacat
     1501 ggactttggg gaataggcac aagatattcc tatataaaaa tgaaggacga acctgacttg
     1561 ggatcacttc gcgatgcttt aatgctaggc gaaactcgag ttcattctga tttttctaat
     1621 ttctccatta atgaaaatga agttttattg gaaaaattaa gcttttctgg gaccactctt
     1681 agcacaaaag aagttgtagt cgaattcagc gataatttaa cttcaattat tggaggaaga
     1741 ggaacaggca aatcttgtat tacaagattc ttggtctatg tccttggaaa ggaagcagaa
     1801 cttgatcaat tttctgaaat acaaagtgat tatcagaact ttgcacaaat tgaacataat
     1861 ggctctggaa tatttttgaa ggatacaatt gtgaaactga atattttcta taaggggaca
     1921 aaatatcaaa taataagaac acaggataga cattctattt atgaatttac acaagagaat
     1981 ggtctggttg aaaaagaaac agaacggttg agaatgattt ccgataaggt gagtatatac
     2041 tctcaaaaac aaatttatga aatttcaaaa aatcaaacta gtatactaga attactagat
     2101 ggatataact ctgatttgat ttcagagtat aaaaatgaga ttgaaacatg tgtaaacgaa
     2161 ataagaaaat taaattggga tattgtttct gtgaaaaaag aaatacaaga taaggcgaag
     2221 gtagagcttg aaattgaaga tttaaaaaaa caagtagaaa agctatctca taagagttat
     2281 aaagatgttt atgatgagta ttcaaaagag acagatattt atagggaact gaaacgtgat
     2341 gtggaggcac ttaaggaaat tcccaaaaat ctaactgata gtgttgacaa aattgacttt
     2401 ggcaatggta taaaagttac agacgaaatt gatgaacacc gcggagaatt gattaagaat
     2461 ttagtgacca atcgggctaa gattcaaaca ataattaatg aaatgtcaga tgaaattgat
     2521 agttatagag cagagctgaa taaatcagat tggaaagtta actataatga ggtttcaaag
     2581 aggtatcaaa gaggtatcaa aaacttagtg aagagttatc tcaagatgaa ttaaaaatgt
     2641 tacaaaacct tgattcttta tatcaatctt tatcaaaaac tgaagagcga ttggaagaaa
     2701 ttattcaaca agaaataaag cttaaagatt accaagttga ggttgactca gcaatgtcaa
     2761 gaatgaataa atcatatcaa aatctctatt ctgagagaag tagttcctcg cgcgaaattt
     2821 tttctgatat tacaggaata gaggctacta ttcaaccaaa tagggatttc aataattatg
     2881 ttaaagagct cagagcttgt attaataagg aggacacttt tgacagtgag tttggatctc
     2941 ttattgataa gctgacaaaa aattccatta ctaatcaaga tatatataat gacatacttg
     3001 atataagagt tagtggggaa agtagtattt tttcagataa aaaattaatc aattctataa
     3061 gaaaattgaa tgatgcacaa gttcttgaat tacaaaccct taagccaaat gatttagtag
     3121 ttatccgact tgaactaaat ggaaaaaaag ttagtttatc gaatgctagt gctggtcaaa
     3181 agacatctgc aattctttct atgattttgg cgtatggaaa ttcaccactc atattggatc
     3241 agcctgaaga tgatttggat agtcaattaa ttaataactt aatcgtaaga agtatcatta
     3301 caaaaaagga aaacagacaa attttaattg taactcataa tgcaaatatc ccagttaatg
     3361 gtgattcaga atggttgatt agcatgggag attcaaaaga aatatcggct gatcagtgcg
     3421 ggtcggtaga tgaacccaat atcaagccaa gaatatgtac tgtgatggaa ggtggcgagg
     3481 atgcttttac aaatagagcg aaacgctatg gttttaaaca aattgtagaa taacactaga
     3541 gggtgagaca tattattatg tccgcccttt ttaggaggaa aaatgaaaaa aataaaaagc
     3601 tataccagta tctgggcagt tgaaaaagtc atttacgcaa tcaatgattt tcagttgcct
     3661 tttcctgtga cttttaacca aatggcttgg ttcgttttat ctttactgtt tgtcatcgta
     3721 tttgcccatg tgcctccact atctatgata gaggaggtct ttttaaaata cttaggcata
     3781 ccggtggctg tcacttggtt tatgtcgcaa aagacgtttg atggcaagaa accactggga
     3841 tttttacgat cctttatcag ctatcacttg cgatttaagg tgacttttgc aggaaagaaa
     3901 gtcaaagaac agaagaaacg atgggatgaa cccagtactc ttgtaaggag tgtgaactat
     3961 gtatccgatt aagtatattg aaaataatct cgtctttaac caagaaggcg agtgttttgc
     4021 ctactatgaa ttagtgcctt acaattactc ctttttgtca cccgaacaga aatttcaagt
     4081 gcatgataac tttcgccaac taattgcgca aaatcgtgaa ggcaagatcc atgcgttaca
     4141 aattgccaca gaaagtagta ttcgcgccac acaagaacga tcaaaaaaag aaattaccgg
     4201 tagactcaaa gaagtagcga aacaacgaat tgatatacag acagatgcat tagtatccat
     4261 gattggcgat agtcagattg attatcgctt ttttattggc tttaaactaa ttgcgacaga
     4321 tgaagaagtc aatctaaaga gtctcaagaa atctttcttt tctgggcttc aagaatttgt
     4381 ctatggagtg aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg
     4441 ctgctattct aagcttgaaa aattaatgga aagcaaattg gctcgaagat ttaaagtcag
     4501 gcgagtcaca ccgagtgacc tgacgtattt gattgaacat atttatggcg aaaaagggat
     4561 accgtttgaa gaatacgaat ttcagctacc aaagaaaaag ctaaaatcag aaacactggt
     4621 gaaacgttat gacttattac gtccaaatcg ttgtttaatt gaagaaaaac caaggtgctt
     4681 acggatggaa catgagaatc atgagtcgta cgtagcgtat ttaacaatta atacaattgt
     4741 gggggagatg gaatttcctt cctcagaact tttctattac cagcaacaac aatttacatt
     4801 cccaatcgac acaagtatga atgtagagat tgtgacgaat aaaaaggctt tagctaccgt
     4861 tcgtaataag aaaaaagaac tgaaagattt agacaatcat gcttaccaat ctgacaatga
     4921 aacgaattcc aatgtcttag atgctttgga ttccgtggat gaattggaaa ccaccttgga
     4981 tcagtcaaaa gaatctatgt acaaactgag ttatgtggtt cgagtgagtg ccgaatcagt
     5041 ggatgaacta aagcgacgct gtgatgaagt gctcgatttt tatgatgata ccaatgtaaa
     5101 actagtccgg ccctttggcg atatgatggg gctacatgaa gaattcttac cctcaagtaa
     5161 acgatatatg aacgactata ttcagtatgt tacgtctgat tttttggcgg ggcttggttt
     5221 tggggctact cagatgctag gagaattaga agggatttac tttggctaca atgtggatac
     5281 aggtcgtaat gtttacctga aaccggcatt ggcttcacaa ggagtcaagg gttcagtaac
     5341 caatgcgctg gccgccgctt tcctgggttc tcttggtgga ggtaaatcct ttagtaacaa
     5401 tctcttagtc tactatgctg ttttgttcgg tggtcaagct gtgattgtcg atccaaaagg
     5461 ggagcgagga gggtggaaag aaaccttgcc agaaattgcg gatgaaatca gtatcctcaa
     5521 cttgacgagt aagtcagaaa atcaaggtct gcttgatcct tatgtgatta tgaagaaaaa
     5581 gaaagactcg gaaagtttag caattgatat tctgactttt ttaacaggaa tttcaagtcg
     5641 agacggggag aagtttcctg tgttacgtaa agccattcga acggtgactc aaagtgatca
     5701 acgggggtta ttacaagtta ttaacgaatt gcgaaaagac gggtcaccaa tcgcggaaaa
     5761 tatcgccgat catatcgagt cctttaccga ttatgatttt gctcatttgc ttttctcaga
     5821 cggctcgatt acccaatcga ttagtttaga taaacagcta aatatcattc aagtggcgga
     5881 tttggtttta ccggatgcag aaacgacttt tgaagaatat accaccatgg aattgcttag
     5941 tgtttcgatg ctaatcgtca tttccacttt tgccttggac tttatccata gtaaccgaga
     6001 aatcttcaaa attgtcgatt tggatgaggc ttggagtttt cttcaagtgg ctcaaggaaa
     6061 aacgttatcg aataagcttg ttcgtgctgg tcgggccatg aatgctgggg tctatttcgt
     6121 cactcaaaat agcgacgatt tattagatga acgtttaaaa aataatatcg ggttgaagtt
     6181 tgcttttcgc agtaccgata ttcatgaaat caagaaaacc ttggaattct ttggtttgga
     6241 tcaggaggat caaagcaatc aaaaacgcct gcgagatttg gaaaac
//
LOCUS       DBBGSP010000105         6173 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000105 DBBGSP010000000
VERSION     DBBGSP010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.106"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            725..811
                     /locus_tag="ACIZE9_002947"
     CDS             725..811
                     /locus_tag="ACIZE9_002947"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGC6094748.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="ACIZE9_002948"
     CDS             complement(932..1621)
                     /locus_tag="ACIZE9_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094749.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="ACIZE9_002949"
     CDS             complement(1628..1906)
                     /locus_tag="ACIZE9_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094750.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="ACIZE9_002950"
     CDS             complement(1866..2780)
                     /locus_tag="ACIZE9_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HGC6094751.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="ACIZE9_002951"
     CDS             complement(2762..3142)
                     /locus_tag="ACIZE9_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HGC6094752.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="ACIZE9_002952"
     CDS             complement(3592..3879)
                     /locus_tag="ACIZE9_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGC6094753.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="ACIZE9_002953"
     CDS             complement(3899..4123)
                     /locus_tag="ACIZE9_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HGC6094754.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="ACIZE9_002954"
     CDS             complement(4578..4748)
                     /locus_tag="ACIZE9_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094755.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="ACIZE9_002955"
     CDS             complement(4763..5296)
                     /locus_tag="ACIZE9_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HGC6094756.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..>6173)
                     /locus_tag="ACIZE9_002956"
     CDS             complement(5317..>6173)
                     /locus_tag="ACIZE9_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HGC6094757.1"
                     /translation="IVSRMREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEK
                     ILSLRFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYS
                     LQQFNELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPI
                     RQELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALAL
                     ADKQKEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLL
                     SDLDNLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DBBGSP010000106         6120 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000106 DBBGSP010000000
VERSION     DBBGSP010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6120
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.107"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(207..1169)
                     /locus_tag="ACIZE9_002957"
     CDS             complement(207..1169)
                     /locus_tag="ACIZE9_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC6094758.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="ACIZE9_002958"
     CDS             complement(1171..2610)
                     /locus_tag="ACIZE9_002958"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HGC6094759.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="ACIZE9_002959"
     CDS             2795..4741
                     /locus_tag="ACIZE9_002959"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGC6094760.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..5877
                     /gene="scrK"
                     /locus_tag="ACIZE9_002960"
     CDS             5005..5877
                     /gene="scrK"
                     /locus_tag="ACIZE9_002960"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGC6094761.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1943 a         1051 c         1084 g         2042 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaggc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg
     5581 aaaaaaggac aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt
     5641 gctcaatgtg cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt
     5701 ggtgtgatga aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc
     5761 aatgggtatg tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac
     5821 aacgctggaa cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg
     5881 aaaaaaggct cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat
     5941 aaccagttag gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat
     6001 gagataaatt cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt
     6061 gcaatagttt tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat
//
LOCUS       DBBGSP010000107         6036 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000107 DBBGSP010000000
VERSION     DBBGSP010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6036
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.108"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     regulatory      complement(20..86)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(128..775)
                     /locus_tag="ACIZE9_002961"
     CDS             complement(128..775)
                     /locus_tag="ACIZE9_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HGC6094762.1"
                     /translation="MEQTIKPYQYFFIIREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILDHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(1183..1686)
                     /locus_tag="ACIZE9_002962"
     CDS             complement(1183..1686)
                     /locus_tag="ACIZE9_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGC6094763.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1809..2573)
                     /locus_tag="ACIZE9_002963"
     CDS             complement(1809..2573)
                     /locus_tag="ACIZE9_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGC6094764.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2681..2956
                     /locus_tag="ACIZE9_002964"
     CDS             2681..2956
                     /locus_tag="ACIZE9_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGC6094765.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            complement(3157..3504)
                     /locus_tag="ACIZE9_002965"
     CDS             complement(3157..3504)
                     /locus_tag="ACIZE9_002965"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094766.1"
                     /translation="MIPSVSFLFKKLKTFFILPEIEESNELTASDRSAFLLPVFNTWG
                     KAPQKQPYRRCSKVSFLVLRQIYAKMWKAIFTKFSLILKTKRLFHNQSLMLDADQLFH
                     NLIDGVLSAASRY"
     gene            3672..4601
                     /gene="yidC"
                     /locus_tag="ACIZE9_002966"
     CDS             3672..4601
                     /gene="yidC"
                     /locus_tag="ACIZE9_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGC6094767.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQPKNSTNNKGRNAGKQQKRK"
     gene            4722..6036
                     /locus_tag="ACIZE9_002967"
                     /pseudo
     CDS             4722..6036
                     /locus_tag="ACIZE9_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320902.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
BASE COUNT         1872 a         1155 c         1110 g         1899 t
ORIGIN      
        1 agaaaggggc tgtccccaga ctttagtagg cgtcattagc tatctttcgt tagcatttaa
       61 aggcgaacac catcacctat tcacttccat taaaagatag catatttttc tgtaaaaaac
      121 aataaaatta tcgttctttc tttacacgtt cagcaaattc atagaaagga gccaatttcg
      181 ttaactgttg attacattgg tcactatcat gacaaatata attccccttt ttcgtatacg
      241 tgccatcaga acctgctttc gttgtagaaa gaaaaagcga aacattcgat gttttctgac
      301 agattgcaca gattccctta tttatcgttg gtgataaagt accgctaatc ccttttaatt
      361 tttcatcttc gtaatagacc atgaattttt tctgcgtacc tggatcattc cagccgatgt
      421 acgtatgttc ttgcaagtcg atttcattcc aagctggttg tttgagtttt ttcacttttc
      481 ggaataattt ctcgatttgt ggtttgctag gctgcataaa cggctgaacg atttgcttca
      541 gctcctccaa tgctctttct gcttgcgctt ttgtcagttt tacgtctaaa actgtcgtta
      601 aaaatgtatc gatttctggc agttcgtgat ctaatatgtc tcgaatcttt tcagctgcta
      661 gtgcctgaac tgtttgtacc gtttttggat cattgacaga tgagtacgca tttaataact
      721 gttctacttc tcttattata aaaaaatatt ggtatggttt tattgtttgt tccatgattt
      781 taaagtcctt tcttctaacc aaagtgcata ctttgtagaa aaaagtgatc ttctgcaaag
      841 tatgtgttac ctgaagatcc tggactcttt taaataagat acgttttgca tcttatcatc
      901 acccccttta atgcttatta ttctatgtac atgattcatt cgataaataa aagtaaaccg
      961 tatcttgaac agatagtcaa ctgcaaacag aaaaaaggac tgtgacaaaa gtcgtgtcaa
     1021 agtcccttgt ttcgaatgaa tggtgttcaa aagcttgcat ctgcagtaat aagccgaaac
     1081 ttcacaaaaa tttgagaagt aattttcgta aattccttct tatttcttga agctgaccac
     1141 ttctgtcaca acctcaatat ggtctattat tggttttacc tgttaaatcg aggattcttt
     1201 cccaaagtaa cgttgccatc tcttacgcat acttgcagac atgggctgag ccgcttcttt
     1261 gactgcgcag tatttgtcca cgaatgtcac aatatatcct tctttatact taggcggtgc
     1321 gatcgttgca ccccacatgt gcttcaaaat gatatctcgc tcaagatccg acaaatcggt
     1381 gattttttct gcattcttta cagcaattct tggatggata tacgcatgtg tcccctcgtc
     1441 aaatttcgtc gtacgccaat catagtagaa cagatcatgc aaaagtccag cacgcgctgt
     1501 tgctttagca ttgccacccc atttttttgc gagcagataa ctatagtaag aaacactgat
     1561 ggaatgctcc aaacgagtgg aatgaacatg ctgtgtgtaa ttcgctaatt ttttcactgc
     1621 ttctgtttct aaaagatctt gtacataaga catatattct tcgtcttcac gccatttttc
     1681 tgtcataatt atcgatctgc cacctttttg aatttcattt tcttctgaaa ttgatctaag
     1741 tataccacca gtgttcggat tattctagtc gctctagata aaatagctaa agcttaatag
     1801 ttccttaatc ataaagaaaa atgataaaga acgatccctg ctgcgactcc gacattcaat
     1861 gattccgcat ttcctttcat tgggatatat acgttctgat cagtcaaaga caagatttcc
     1921 tgactgactc cctgaccttc gtttcccatg attatagcga aatcctctgt tttttctact
     1981 ttgtctaatg catgtgcttc ttcatttaat tctgtaccgt acaccgtaaa ccctttgcct
     2041 ttcattacag ggattacatc tgccaaatct ttttgtaaca caggcaaatg ataattgctt
     2101 ccctgcatgc ttcgcagcac ctttgtacta taaatatctg ccgttccttt acctaataaa
     2161 acaccagcca taccaaacgc atctgccgta cggatcatcg ttcccacatt tccaggatcc
     2221 tgtacattat ctagtaaaag ccagcctcct gaaaaatctg gcgtatcttc agatgttaac
     2281 gtcatcactg ctaagatccc ttgcggtgta ggtagatctg acatagcggt catgacctca
     2341 tctgaaacta gaaaagtaga aatctctttg tttacagcca gccagtctcc ccattctttc
     2401 atacctctct gtgtcacaaa aagttctttt atttctgcat cagacgacgc agcttcttcg
     2461 atcagatgga acccttccaa aagatattct gccttttctt ctctgtattt ctttttatgt
     2521 agttttttta attctttgat tcttggattt tttgctgatt ggatctcttt cacattcctt
     2581 cacctcacct gattatatca tggaataggt gcttgagctt gtttcatcct aaaaaaatcg
     2641 gtatcattga tttataaaac aggaaagaaa ggtgacgaac atgcgcaaag ttaaaatgaa
     2701 tgtccaagga cgtgtccagg gcgtgggatt tcgctatatg accaagatgg ttgctgatca
     2761 gttaggcgtg accggaacgg taaaaaacga agacgacggc tcagtcacaa tcgaagcaat
     2821 cggaaatgac gacatcatcc aaaaatttat cgaagaagtc aagaagtctc cgagcccaag
     2881 tggacgagtg cagtatgtgg atgtccaaga agatccgatg attgaggaac gaaagaaatt
     2941 tgatgtggtg ggataaggtt gtgaaaaggt cgcttagttt tgagtattaa ggaaaatttt
     3001 gtgaaaatgg ctttccacat ttttgcataa atttgactta ataccgagaa actgactttt
     3061 gaacaccgtc gataaggttg tttttgaagc gctttgcctc gagtattaag gagaaacatt
     3121 ttcaaaatag cttctcatat tttgaaatgt aatgacttaa taccgagagg cagctgataa
     3181 aacaccgtca ataaggttgt gaaaaagctg gtctgcatca agcattaagg actggttgtg
     3241 aaaaagtcgc ttagttttga gtattaagga aaattttgtg aaaatggctt tccacatttt
     3301 tgcataaatt tgtcttaata ccaagaaact gacttttgaa caccgtcgat aaggttgttt
     3361 ttgaggcgct ttgccccaag tattaaagac aggtagtaaa aaagctgatc tatcacttgc
     3421 agtgagttca tttgactcct ctatttcggg cagaataaaa aaagttttta gttttttaaa
     3481 taagaaagaa acacttggaa tcactctttt ctttccaagt atttctttct tgattttttg
     3541 tcttttttca aaatttttcg ctacgaaaaa gaaagaatat ttatatgaaa tttctatgaa
     3601 gttgattgaa ttccatgcgc ttttttagta tagttaagtt tgtgtaaaaa ttatagaaga
     3661 ggaagtattc tatgaataaa tggaaaaact ggttattggg atccggactt gtcagtatcc
     3721 tgctcttttt atctggctgt gtgcggatgg attcaaacgg aaaccctgac acttcaggaa
     3781 tcgtttatcg agtactcgtc catcctatgg gccaagcgat tacatatcta gttgagaatt
     3841 tcaattggtc ttacggctgg gcagttattg caatgactgt gatcgtccgt atcatcatct
     3901 tgccactagg tatcagtcaa tcaaaaaaaa caatgatcca atctgaaaaa atgcaagcgt
     3961 taaaaccaca agttgaagca gcacaacaaa aactaaaagc tgcaacaaca cgtgaagaac
     4021 aaatggcagc acaagcagaa atgcaacaag tatatcgcga aaacggattg agtatgaccg
     4081 gcggaatcgg ctgtctgcct ctattgatcc aaatgccgat cttctctgcc ttgtatttta
     4141 cggctcgcta cacagaaggt atccgtgaat catcttttta cggcatcgat ctaggctcac
     4201 caagtatggt gcttgttgcc attgcagggg tcgcttatct gcttcaagga tatatttcaa
     4261 caatcggtat tcctgaagaa cagaaaaaga cgatgcgtac gatgctgatc gtctctcctg
     4321 ctatgatcgt tttcatgtcg atcagtgcgc cagccggtgt tacactttac tgggtagtgg
     4381 gtggtgtgtt cagttgtctg caaacattca tcacaaacgt tatgatgaaa ccacgtttga
     4441 aagcacaagt ggcagaagag ttgaaacaaa atccgccaaa acaagtcgtc actccaagaa
     4501 aagacgtgac agaatcggca aagccagctg acaataaaca accaaaaaac agtacaaaca
     4561 acaaaggccg caacgcagga aagcagcaaa agcggaaata aaaatatatg acaaaaaact
     4621 gtagacaaat aaaaaaattt ctttgttcta cagttttttt gttacaatca aagaaaacgt
     4681 cgcttttcga ggaggaatgt ataatgatgt ccaaataatc aatggatagt cgaatggaag
     4741 aagccaaaat ttcgctagat gcacttgttc ctaaaaatca tttggtccat aaaattgaca
     4801 aaatattgtt atttgatttt atttatccaa ttgttgaatc aacttactcg accattggtc
     4861 gtcctagcgt tgatcctgtc atcttagtaa aattagtatt cattcaatat ttatttagga
     4921 ttcgttcgat gcgtcagtcc attaaagaag ctgaaacaaa cctagcttat cgttggtttc
     4981 ttgggcttag tttaatcgat aaaattcctc atttttcaac gtttggtaaa aactatgtac
     5041 ggcatttcag agaaaccgat tgtttgaaca gatatttatc attatccttg aacaagcagt
     5101 tgaagctaga tttattcatg aagaaatttt gtatatggat tcaacctata ttaaagcgaa
     5161 tgcgaaaaaa catattttta caagagaaat ggtacataaa taagccattt tataccaaaa
     5221 acaattgaaa gaaaaaatta atgaagcaag aattgcagaa ggcaaacgtc cttttggttc
     5281 aatcattcat caggaggtgg tagaagggaa aattagtgtc gcagatccag aaagtggtta
     5341 ttatgtaaaa acagaacaag aaaaacagtt tgcttattct gctcataccg tttgtgatga
     5401 aaatggtttt gtattagatg tcatgattac gcctggaaat ctacatgaca gccgaatgct
     5461 cgtgccacaa atcgaacgtg ttaaatcatg ttgtggtgta gctgctgatg ctgcgtacaa
     5521 aacaccttgg aacgccaagt atttaatcga tcgaaaacta cgacccattt ttccttatac
     5581 tcgacccaaa agaagcaaag aacgttttaa aaagaaagat ttttattatg atccctatta
     5641 taactggtac ctatgcccaa atgatcaaac acttcagttt cgcacaacta ctcgagatgg
     5701 ttataaaaaa tatgtatcta aatcttttat ttgtgaaagt tgtctattat tgaaaaatta
     5761 tacagaaagc cagaaacacc agaaagaaat acatcgacat atttaggaag actacttaga
     5821 tgaagcagaa catttacgcc atacggtgta caatcgcgaa aaatataaaa aaaagaaaag
     5881 aaacgattga acgcgttttt acagacgcaa aggaaaagca tggaatgcgc tacaccaaat
     5941 atcgaggctt ggaaaaaacc aggtgcatac gatgcttgtt tttgccgcaa tgaatctgca
     6001 aaaattagcc atttggcagt gggggcatat gtcttt
//
LOCUS       DBBGSP010000108         6029 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000108 DBBGSP010000000
VERSION     DBBGSP010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6029
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.109"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(68..370)
                     /locus_tag="ACIZE9_002968"
     CDS             complement(68..370)
                     /locus_tag="ACIZE9_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HGC6094768.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(590..956)
                     /gene="ssrA"
                     /locus_tag="ACIZE9_002969"
     tmRNA           complement(590..956)
                     /gene="ssrA"
                     /locus_tag="ACIZE9_002969"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1127..1900)
                     /locus_tag="ACIZE9_002970"
     CDS             complement(1127..1900)
                     /locus_tag="ACIZE9_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC6094769.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2044..2394
                     /locus_tag="ACIZE9_002971"
     CDS             2044..2394
                     /locus_tag="ACIZE9_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HGC6094770.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2375..3091
                     /locus_tag="ACIZE9_002972"
     CDS             2375..3091
                     /locus_tag="ACIZE9_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HGC6094771.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3091..4539
                     /locus_tag="ACIZE9_002973"
     CDS             3091..4539
                     /locus_tag="ACIZE9_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6094772.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4610..5119)
                     /locus_tag="ACIZE9_002974"
     CDS             complement(4610..5119)
                     /locus_tag="ACIZE9_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094773.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5109..5834)
                     /locus_tag="ACIZE9_002975"
     CDS             complement(5109..5834)
                     /locus_tag="ACIZE9_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094774.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         2052 a         1050 c         1170 g         1757 t
ORIGIN      
        1 aaaaatatcc cttttataag tatggtgata aaatccgttc cgggctacct tttttaggta
       61 gcctacttta atctttatac ctttctggat caacgaaagt atacttcaaa tagtcataac
      121 gccgatgatc gctccgtgcg tctggcacat cagtcacgat atcaaacaaa aaatacacat
      181 ctttcttcat tctggttttt gttgccggaa ttttaaagta gttcttatta gagtaataga
      241 gattgattaa taagctatct tcgattgcta aaaagaaaac ttctgaatcc cacaccttat
      301 aaaaatcttt gacaaatcta ttcgaaggat caaatttaaa ccataattgt gtttttcctt
      361 ccatcaacat aatgttcacc tcaaaaagag tatacgaact aatgttcttt ttgtaaagta
      421 ggaatatcat tgataatatg gatggaacat atatattaaa aagtgttctt tttgaatgct
      481 attttgaatg ccattttcat tcatttaacg aaaatctgcg aaaataaaaa atgctcaaac
      541 ccttataaaa taaggattta agcatctagc gaaatctgct gaaatctcac aatggagacg
      601 gcgggagtcg aacccgcgtc caaacacatc gccacttaaa aatctacgtt catagtcaac
      661 tcatttaagg attcacttta cagcttgccg agtgacaggc attctgtatc gctagtctga
      721 tgttctcttt ttcaacttac agacggaaag ttgaaacgta tcccactaaa gttaggaccc
      781 ttactcgagc acatgggcga tgccgagagg atctacgcta actgttttta ggcagctaaa
      841 gcgtaagagt tgttttcgtt tttagcagtt atatttaact gtaacgtttt tacgtagacg
      901 taacctacga aacgcaattc aagctcgact gtgcctgtcg aatccgtaac gtccccgtta
      961 gctaacaagg gttacgtgta tttttcatac aaaattagta tagcatatat tgggataaat
     1021 tcaataaaaa agcgaatcat atcccattat ttatataata actgcccctt tcttaagaaa
     1081 aaataagcga ttttcttaag aaaagaggta gcttcaaaaa aagatcttaa atcagatcaa
     1141 aatacttcaa tgcgtggaca attccgcctt ctgtattttt ctttgtgata aaggtagaaa
     1201 gttcttttaa tccgtcatag gcgttgccca tagcgatttt gttgtcgcaa gcttccaaca
     1261 aggcaaaatc attcggacca tcgccaaatc caaaagtagg aactttttcc agctgaagtt
     1321 ctttttgcag acgtttgaca cctgcccctt ttgagattcc tttcttcact gtatcgatcg
     1381 agtaaggacc attccgataa aaagttagct caggaaaatg ttcgtgatag tattcgtcac
     1441 ctgattgaga taagatcagc aacatattta ctgtgttttc tttaaagcct aaaggatcaa
     1501 tttccggaac atctgaatga atgaagtcgt aagcattgat cattgtttgg ctatgaccgg
     1561 tacaccagat tttctgatcg ttatagtaag aaagttcatg accgttcaac tgtacatgat
     1621 catacatttt ttgacattct tctgaagaaa atgtttgaga atagatttct tcgccgtcta
     1681 ctcgaatgaa agaaccattc atggtgaccg cagaagtaat gcccgcatct tccatgatag
     1741 agtggatttc tgcttctgta cgtcctgtag cgatgacggg gagaacattg ttttctttta
     1801 atgcgttcat agcttttgcc acttcgggtg tgatttttga tttcgcatct agtaatgttc
     1861 catcaagatc aaagaaagtg attgcacgat aatttgacac aaataaaact ccttttttat
     1921 tggaataagt ttatcttaac aaagaatgaa caaaagacaa acctttcgtg aagaattcct
     1981 gaacatattg gttcagtcaa caatttagag tatactataa gaagagaatt taggagggaa
     2041 agaatgattt ttttcagtat tggtatctta ttcttaataa ttggcagtct ttttcggatt
     2101 ctgccctcaa aaggaaatct gcctttttat gggtatcatt cgcctcttgc cgcaaaaaca
     2161 gacgctcatt ggcggctggc tcaaaagaca agcggaaact ggttttttct tatgggctta
     2221 ctgatggcat tgatcggcta ttatttaaag acatctgggc atacgaatta ttttctgatt
     2281 gaaatgcttc tgctagtatt tccaattatg cctattttta ttatgacaga aaagaaatta
     2341 cagaaatatg acctggaaac tggagggaac gataatgaat attttaatga ttgaagataa
     2401 tcaatctgtt tctgaaatga tgcagatgtt tttcttaaat gaaggttggg aagcaacttt
     2461 caagtatgat ggaaaagaag ggctcgatgc ctttttagaa aacccacaac attgggatat
     2521 gattacacta gacctgaatt tgcccacact ggacggtatg ctagtaggaa gagagatccg
     2581 caaagtttca agtactgtgc cgattatcat gctgacagct agagattctg aaagcgatca
     2641 ggtgatcggc ttagagatgg gggcagatga ttatgtcaca aaacctttca gtcctctgac
     2701 gcttattgct cgaatgaaag ctttgcatcg ccgtagtgag ttggcagaag caagagaaga
     2761 agcagtagtt tcagatgatc attttgatat cgagactagt catttcaaga tgaatacgaa
     2821 aacacgagaa gcgtatctgg acaaccggcc aattgaagga ctgacgccta aagagttcga
     2881 tctattgttt actttagcaa aaaaaccacg tcaagtattc tctcgggagc agttgcttga
     2941 attagtctgg gattatcagt actttggtga tgaacggaca gtggacgccc atatcaagaa
     3001 attacgacaa aaaatcgaaa aggtcggacc acaagtcatc caaactgttt ggggagtcgg
     3061 ctacaaattc gatgattctg gtgttgccta atgcgttatt tgtatcagca actcttagct
     3121 ttctgcggaa tggtcgcgtt gatcttattg atcgttggag tttcttttac acaactgaca
     3181 aaacaaacga ttgaagaaaa caattaccag caactgtttg gatatgctga atcagttgaa
     3241 aagacaacgc aaacctatgc cgatacgctc ccgcagttta gtcaagatca ggcgtttcaa
     3301 aatgcattgc tgctgacaga gcaagtactg acagaacaaa atgtgaactt tatatttatc
     3361 gataaaaacg aacgtgtcat ttatccgact aatacagctt tactgaattt taccttaaca
     3421 gctgatcaat ggaaaaatct gaggaatgga cgtcaagaaa aattcacatc gaataaaaat
     3481 attttaggac aagcacaggc gacctcttac gcacttgtgc catttaattt gaatcatgaa
     3541 ttctatggag cacttgtagt tagtcaacct gcgcgaaata tcgataacag cgttcgtcca
     3601 attacactga acctgttcaa aggatttatt ttttccagta tcgttgcagt tattgccagc
     3661 tatgcttttg cagcattcca agttaagcgt atcaatcggt taaggaatgc gacgaaagaa
     3721 gtgacgaatg gtaattttga tgtacagctc cccgtacatg acaaagatga atttgatgag
     3781 ttagcagatg atttcaataa aatgacgaat tcattgaaag aatctcaagc agaaattgaa
     3841 gaacaagaaa atcgtcgaag acaatttatg gcagatgctt ctcacgagat gagaacacct
     3901 cttacgacaa tcaacggact tctggaaggg ttagaataca atgcaatccc tgaaaatcag
     3961 cgagaaaacg cgattaaatt gatgaaaaat gaaacagagc gtctgatccg tttggtgaat
     4021 gaaaacttgg attatgaaaa aatccgtacg aatcaaatca gtatggtcat taaaaaattc
     4081 aatggaacag aaacattgaa aaatattgtt gcacagttag aagctaaagc agaagcagca
     4141 ggagatacat tgacattgaa agccgttgat gatattgatg tttacgctga ttatgaccga
     4201 tttgtccaaa tcatggtcaa tattattcaa aacgcgatac agtttactga aaacggccaa
     4261 atcacgatta ctttagaaaa aggctatctt gaaacgatca tcacgattga agatacggga
     4321 attggaatgt ctgaacaaca aatgaaaagt atctgggatc gttattataa agtagatcct
     4381 tcaagaaaaa atacaaaata tggtgaatca ggattaggtt taccaatcgt gcagcaactt
     4441 gtacgcttgc ataaaggaaa attagaagta gaaagcgaac taggaaaagg aacaaaattc
     4501 gctgttcgtt tgcctgacgt agaaatcaaa aaagagtaaa aaacaagcgg tataaaagat
     4561 catgaatcga tcttctatac cgcttgtttt ttactataaa atgattgatt tagcccgcgg
     4621 gctctaaacg atcaatataa ggactttgag caatagtagc atcatgagta aagagtaaga
     4681 taccttgatt ttcttcatga gctaaataag aaagcaagtg gagtagctct tggatctcca
     4741 atacactaag ttcatcaaat gtatcttcaa taacaatatt gtttcgcttg gaaagcaagg
     4801 catgaagtaa ttgcagcttt actttttcaa aagacgtcaa ctcagctgcc gcacaattaa
     4861 gcaaggaagg agagatatca agtttttctt gataggccaa acgatcttgt ttgatttctt
     4921 tttccggtac atccaacagg acatggtctt taagattcag ataaggaaac atcggccaat
     4981 ttttttggat gatcgcaaaa ttatccagtt ttgcaacaag aacctctttt ttcaagtgct
     5041 ccaatatttt atgctgtttt tcgagaggac acaaaataac ggtcaagtgt tcagcatgaa
     5101 tcaaatattc aggtttcatt acgtccaggc ctcctacttt gcaaatgatg gataaaaaaa
     5161 gtgaaaggga atagactaag aatgagacag catccactga gcccaataag agtttgggca
     5221 aatcccttaa gtatatctgt gaaaaaaaga tcattttgga aatcgatggt aaaaaaagtc
     5281 tgttgatcca tcggaattgt aagtccgctt accgaagtca agatatcacg gatatctggc
     5341 agttcagtag tctttaagac aagaaaattg atcctttgaa gaagcgcttc ataaactgac
     5401 tggaagctta cgatccacaa taaaaccaag atacaacaaa gaaagagagg aaagaacagc
     5461 tgccagaaaa taaaaaggaa taatttggtt ttagaaagac cagtcaggtg ccaattgatc
     5521 aattcctgct tgttttgcct gactgaatag taaaagaaaa agataaaaag gaaggcaaat
     5581 agaaaaaata aactgaatat gccttttata taaaatcggc tagctaattc taaagccgga
     5641 agaagctctg tagatgcaga agcgccaata aatgaaagcc gatcttggac ttgattggct
     5701 aaagccgatt gcaaatggta aagagtcagg catgctatca ataaaaaagc agaaaagctt
     5761 gaaaataaac aatagagtat tgtctgcttt ttgtaataaa ttaatcgagc agtagcatag
     5821 cggattattt tcatactttt cacctctata aaaagtatag aaaatgaata tgaataaagt
     5881 atgaaattcc tttagtgaaa tcacgaatta aaaccagaaa atattttgta aaaagcaaga
     5941 ggttgtgaag aagctgccct attctattac cgtagatgca agcttttgaa cactgtttat
     6001 tcgaaaagag gagcagcgac aataatttt
//
LOCUS       DBBGSP010000109         5925 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000109 DBBGSP010000000
VERSION     DBBGSP010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.110"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(76..1170)
                     /locus_tag="ACIZE9_002976"
     CDS             complement(76..1170)
                     /locus_tag="ACIZE9_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HGC6094775.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            1359..2120
                     /locus_tag="ACIZE9_002977"
     CDS             1359..2120
                     /locus_tag="ACIZE9_002977"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC6094776.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(2235..2675)
                     /gene="fabZ"
                     /locus_tag="ACIZE9_002978"
     CDS             complement(2235..2675)
                     /gene="fabZ"
                     /locus_tag="ACIZE9_002978"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGC6094777.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            2895..3650
                     /gene="fabI"
                     /locus_tag="ACIZE9_002979"
     CDS             2895..3650
                     /gene="fabI"
                     /locus_tag="ACIZE9_002979"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HGC6094778.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(3760..4812)
                     /locus_tag="ACIZE9_002980"
     CDS             complement(3760..4812)
                     /locus_tag="ACIZE9_002980"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGC6094779.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            4938..5858
                     /locus_tag="ACIZE9_002981"
     CDS             4938..5858
                     /locus_tag="ACIZE9_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HGC6094780.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
BASE COUNT         1806 a         1181 c         1063 g         1875 t
ORIGIN      
        1 cctataaaaa aacaaaataa aaaagcagaa ataactggct atttctagcg gattatttct
       61 gcaataacta attatctatt ttttattttc aattaattta aagcttgacc atggtttcaa
      121 aaagtcaagg aggaataatt cgtcatcgga gattcttcct acaacattga cacgtccgtc
      181 gtttttcata tccttcaagg cgatttgtgt ttctcctttg tattgaccgt acccttcatt
      241 gtcaatcagt acatccccat gatgcatatc tcgcgtatta tgaggcggga aatctttatc
      301 tttgtagtat acacgagtca tcgttgaacg aaggatatat tctgagcgat cccctcgata
      361 actatgaagg ttatcaaaca agcagattcg ttcgttttct gtaatacctt cttccgtatc
      421 tactttcaat gttggataat ccgcgttaaa tgcttctgcc atttctttca attcttcttc
      481 acttgcgtac gcatttccaa tagaaatatc atcaatcaat cctgtaagga ttaaatgctt
      541 cacttgtgtc gcaatttcaa gatctcggtg gtcttccagc gtgcacaagc catcttgcgt
      601 aggccaaggg ccaaactcag cagattgcga attgacgaat gccatcgtat tcaaattata
      661 ttttctgaat ttttctgaac aaaaaacaaa gtgttcgtat cctaaaccag agtatcgatg
      721 aggataaaaa ttatgagaac ctaataaatt atccgtgttt ggcgaataac tcatgatgtt
      781 gtcaacgtaa ttcgtgcccg aactcatatt gatctcgatt ttgataccaa aaggattgcg
      841 cgtcattttt gcttcttctg ctcctgtgaa tccgatatct aagcggaccc cgtaggcacc
      901 catcttatgg aaaaaagata agtcatcgta agaaatctcc aactgttcaa ataacgctgg
      961 attgatatca accattactt ccatgcctag gctattcgcg taatcaacta cttctttaaa
     1021 ttctgaaaga actttttctt tatcatcatt gatctgcagc aaactggtaa aaacccgttt
     1081 atacccatac ttatgagcta aatccaagta cgctttgtcc ttttcaaatg ttgaccgttc
     1141 tggataaatc gagattccta attttcccat attaccattt cctcctgcat cttttcgttt
     1201 ttgtatccac ttacattata gcaaacacaa agtaaatggt ctacaccttt tctttttctt
     1261 ttaaaataaa tgataaattc caataattta agtaggtatt ttccctctat tttgttatca
     1321 ttaaagataa caaaatagta aattggaaag gaacagttat gaagaaaaat aaagttattt
     1381 taagtattag tttagcagca gcattgctgt ttgctgctgg ttgttctgca aacaacacga
     1441 cttcttctag ttcgtctaca gaaagttcaa aaagtacatc tactgcggaa agcacgactg
     1501 ccagtagcgt cgatttgaac gcattggaat taccacaatt gacgaaagat gtcgccgaaa
     1561 atgaagatct ggtcgaaatg gtgacgaata aaggcacaat caaaatcaaa ttatttcccg
     1621 aacacgcacc aaaagcggtt gaaaacttta tgacacatgc aaaagacggt tactacaacg
     1681 gactgacttt ccatcgcgtc atcaaagatt tcatgatcca aggtggcgat cctaaaggcg
     1741 atggcactgg aggggaaagc atttggggag aaggatttga aacagagatc aacaaccacc
     1801 tttataatat aagaggtgcg ttatctatgg ctcgctcaca agatcctaac agtaacggca
     1861 gccagttctt tatcgttcaa aatacagatg atatgcatga tggtctttta aaagacgact
     1921 atcctcaagc aatcatcgac gcttataaaa acggcggtta tccttcacta gatggccatt
     1981 atactgtctt cggccaagtg attgaaggaa tggatgtcgt ggatgctatt gcaaatatcg
     2041 aaacagatag ttcagacaaa ccaaaagaag aagtaaaaat cgataaaatc aatatactgc
     2101 aagaagcaaa acaaaaataa aaaaataacg tctgaatcct gcatagatga caacgtatgc
     2161 taggattcag gcgtcttctt tttacataaa aagcaagtaa gcttcctttt gttttgctat
     2221 atcaggtttt atagtcaagc attttggttg acgatgaacg tgaactcgca ctcacagact
     2281 tttttatcat ctacatatgc tgcagataac gctgtaccga ctgatccctt cattttggtg
     2341 atttcaaaat gacatttcag cacatctcct ggaacaactt tttgacggaa tttggcctta
     2401 ttgatcccac cgatataagc tctttttcct agaaactctt ctgattttag gataagtatc
     2461 gaacctgctt gtgccagtgt ttctagaatc aacgcacccg gcatcactgg attgtcagga
     2521 aagtgacctt ggaaaaaatc ttcattgatt gttacatttt ttgtcgcaac gatctttttt
     2581 cctggttcta aagtatctac ataatcaata taacaaatag gataacgatt aggaatcaat
     2641 tccattactt cagtagcaga taatacgtaa gacataatta aactccttct ttcaggcaat
     2701 tgccattttc attactttga ctatcaaagt atcatattcc taaatattta gcaatctttt
     2761 tttaatttaa gaaaaaatag tttgacaatc aaaacatttt gactaataat taagaaatca
     2821 agaagttatt ttagctatta ttctctattt ttttacgact atcaaatttt tatcagaaac
     2881 aaaggagagt cattatgtca tttctagaag gaaaaaaaat cgtcattatg ggcgtcgcta
     2941 acaaaaaaag cattgcttgg ggttgtgctg aagcaatgtt gaaacaaggg gcagaaatta
     3001 tctatactta ccaaaatgaa cgaatgaaaa aatcattagt caaattggtc ggcgaagaag
     3061 cattcactgt agaatgtgat gtttctagcg acgaaagcat cgaaaaagca atgaatgcca
     3121 tcggtgaata tgctggggag atccacggcc ttgtccatgc agttgcttac gccaacaaag
     3181 aagaattgtc cggaaatgtg tctgatattt ccagagacgg ctatcaatta gctcaagata
     3241 tcagcagcta ctctttaatt gctgtatcaa aatacgcaca accgtttctt gcaccaaaca
     3301 gcgggatcgt tagcatgact tatctaggtt cagaacgcgc aatcccgaat tataacatga
     3361 tgggtattgc gaaagcttct cttgaagctg ctatccgtta tttggcagct gagttctcgc
     3421 ctaaaggaat tcgggtcaat ggaatctcag ctggggcaat caaaacatta gctgtcacag
     3481 gtgttaaaga ctatcaaaaa ctgatccagt tatctgaatc tcgtacgcct gatcagcaag
     3541 gtgtgacgat cgaagaagtc ggtaatgctt gtgctttctt aatcagccca ctttccagcg
     3601 gaatcatcgg tgatattatc tacgttgaca aaggtgtcca tctttcataa acttttgttg
     3661 cattctttaa agtaaaacat ataaaaatca ggaaaaaact ttttaaagtc tcttcctgat
     3721 tttttctttt tacgtttttt tcaactcatt actttgaaat tattccacga cttcaatcca
     3781 gccttctggt gcttctatgt ctccaaattg aatacctgtc aattcatcat acaaccgttt
     3841 tgttactggt cctacttccg tttcactata aaatacatga agattgttat tgtgataaat
     3901 cccaccgatt ggagaaataa cagccgctgt accacatgca ccagcttctg caaattgatc
     3961 tagatcatca atgaaaatat ctccttcaat tgcttgcagt cctagtcgtt cttcagctaa
     4021 ctgcaacaag gaatatttcg tgatacttgg taagatagag ggcgattgcg gagtgatgaa
     4081 ttttccgtct tttgtaattc caaagaaatt tgctgcacct acttcttcga ttttcgtatg
     4141 tgtggctgga tcaagataaa cacaatctga gtaatccagt tcttttgctt ctgttcctgg
     4201 aagtaaactc gctgcgtaat ttccgccgac ttttgctgca ccagtcccct taggagcagc
     4261 acgatcgtaa tcagatacaa taaaattcgt tggttttagt ccacctttga aatacgctcc
     4321 tactggcgta cagaagacga caaataaata ttctggagct ggatggacac caatgttttc
     4381 accgacccca atcagtaaag ggcgcaagta taatgtagcg cctgttccat agggcggcac
     4441 aaaatcttca tttgctttta ccacttgctt gacagcatca acgaacatct tttcagggac
     4501 cattggcatc agcaatcgtc tagcactttg attcatccgt cgactatttt gttcaggtcg
     4561 aaagagattg accttgccgt cttttcgacg ataagctttt agaccttcaa aacattgctg
     4621 accataatga agcgctggag agccttcatg aatcgtcagg taattatctt ctgtcaattc
     4681 tccttcttcc cattgtccgt ctttccattt ggcaataaaa cgccaaggag ttttgatata
     4741 agaaaaacct agattgttcc aatcgatttg catatactta ccaccttcgt tattttctcc
     4801 acattttatc attatccata ttatttgtca ttttattttc agcttttttc cttcattata
     4861 gttatttttg ctatttcctt ttttgaaaac ttcttggtac aatacagaaa gaatcaaatt
     4921 ttagaaaaga ggattttatg ttttcattat tagcaactgc cggtacgaca gactcttctg
     4981 gcgagacatt gacagatcaa gctgtcagca aagtaaatgc gtttcagcgg ttttgggacg
     5041 ggattgattg ggacgccatt ttggctgcct ttatccaaaa aagtttatat ctgatttttt
     5101 tgatcgtcct tttttggatt cttcaccgtg tgggaaaata tctgattgat aagtctttta
     5161 atcagtattc taaaaaagcc attctaaacg agagccgctt aaagacttta catagtcttt
     5221 taaatactat ttttcattat acccttggtt tcttttttat ctatgcaatt ttatctgcta
     5281 tcggtgtgcc gatcggatca cttttggctg gtgccggaat tgcaggtgtg gcaatcggtc
     5341 ttggtgccca agggttcatg agtgatgtta ttaccggatt ttttattatc atggaacaac
     5401 agatggatgt tggggactac atcaagctag caaacttaac gattgaagga accgtcgtat
     5461 ctgttggtat ccgtaccctt cagctgaaag caacggatgg tactgtccat ttcatcccga
     5521 atcgaaacat caccacgatc agcaatctct ctcgtgcaaa tatgcaagta cttttagata
     5581 ttcggattgt tcctgaagaa ggatatgaca aaatctatga gatcattgat cgagtaaatc
     5641 gtacattagc tgaaaaatac caagaagagc tccaaactga accttctatc tttggattag
     5701 tggatcttgg aaacagcaat tttgcgattc gtacggtctg ctacgcattg aacggaaaac
     5761 aatatgcctt aaaagaagag ttcttgagct cctatgtcaa agaattgaca gcttctggtt
     5821 tcacgattcc gaacagtcca attgctgtcg gaaaataatt tggacaaacg atgcaacgaa
     5881 tctcactaaa aagagcgtgg gacaaaagta aagaacactt ttgtc
//
LOCUS       DBBGSP010000110         5907 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000110 DBBGSP010000000
VERSION     DBBGSP010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.111"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(368..1486)
                     /locus_tag="ACIZE9_002982"
     CDS             complement(368..1486)
                     /locus_tag="ACIZE9_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094781.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1719..1841
                     /locus_tag="ACIZE9_002983"
     CDS             1719..1841
                     /locus_tag="ACIZE9_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094782.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            1957..3264
                     /locus_tag="ACIZE9_002984"
     CDS             1957..3264
                     /locus_tag="ACIZE9_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGC6094783.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3383..4582
                     /locus_tag="ACIZE9_002985"
     CDS             3383..4582
                     /locus_tag="ACIZE9_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HGC6094784.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4609..5877)
                     /locus_tag="ACIZE9_002986"
     CDS             complement(4609..5877)
                     /locus_tag="ACIZE9_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HGC6094785.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
BASE COUNT         1813 a         1251 c         1058 g         1785 t
ORIGIN      
        1 tttttaaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt cacaaaaatt
       61 tgagaaataa tttttgtcaa tctcttctta tttcttgaag ctgaccactt ctgtcacaac
      121 ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagcccac caaacaaaaa
      181 atatgaagag ctatttttgc ttgctgttct tattacttga tgcagaacag ctttttcaca
      241 acctctcata cacggtgttt aatcagctga ccttcggtat tagctcaaaa aacggaaaaa
      301 tatgtgaaac tatttttccg tttgtttctc taatactcag gtcaaaacac tgatttcaca
      361 acctctttta ataacgaaga atcgctgtca gactcttttc atctggcgca tctttttgat
      421 ccaaaataaa cactttcccg ccattaatga tcacatcatc tgctaatgca ttcaacactt
      481 gacgccgatc atattctgtt tcaggatctt caccgaaacc atcagctaag tttgacgtag
      541 cgataaataa atgtgacact tttccttctt tcgcagctgg aacgatatca actaactgat
      601 cgatgaattt cttatctaag agtttattgt attcttttga ttcttgagct gcgagttcac
      661 ttgacagctt cttcgcccct tcttcgatat ctctaaagga tagctgcgca ggagaagcag
      721 aaatcgcaac gtctgcacaa taatagggat ttttagcaat ttttttgaac atcgtctgat
      781 tttctggtaa tgcaaataaa taaatcggcc attgttcagg attttcgaaa gaatccttca
      841 agtacgtatc aacagcttgg taatagttga cccaatcgat ctctacttct tcatcttttg
      901 gatttacgcc atggaaagtt actccatctc gggctccgcc tcctccatta gaagagaagt
      961 tcaaaccgcc acctgtcagt tcagatccca atgcagtaac gacatcaacc ggtgcccctt
     1021 ctggtagaga tacttctttt acttgtttgt tgctgacctc atacaatttc atggagtcgc
     1081 ggttcaatcc caataaataa taagaatagt tgaactgccc atttttgata atagccagta
     1141 aataaggaag atcacttaca tagtattgat cgtctaccgg gatactcaaa cgatggatat
     1201 aggtctggtc agcagttata atgaccgcta cactcgtagt tgcactacgc caaaacgaag
     1261 gatctcctaa caaattttca attttttctt ggaacgggga ccagtcatgt tcggaatatt
     1321 ttttctcaaa acgtttcttt gcttctttcg caaaattttt gaatttgatc tgatcttttt
     1381 ccacatcttg atgggcgaca tgcgtattca gcatgatcgt gacgaatggt cctttagcgc
     1441 cttctgaagt caattgtgtc aataattctt tatccttttt tgccataaac gtacccctcc
     1501 taaaaaaatc attcctttgt ttctatctaa agtctaccac aacactattt ttccatacaa
     1561 taaaacgtat ctaaaaaaat aaaacggttt ctacggtttt aaatttagct atttttttaa
     1621 gttatcttca taatttcctc aattatttag ccccagtctt caactattct tcatgaaatg
     1681 ctgataaact aagaaaaaga ataaaagagg tggatcttat gcatttgatt atgattttca
     1741 gtttattaag tattatcagt ttatttgctt tcagcgcttc ccgcttatta gatgcggaaa
     1801 cacagcctat tcctgtaaaa gtacgtaaaa acgaccgcta aacttccata acgcgcgttc
     1861 ttatcctaaa gttttttcag aaacattgaa actctctccc ctctctgata aaattttaat
     1921 ttgtagcgaa acaaattaat tacaaggaga tcggatatgt ccataaaaaa aacacgtcta
     1981 gtcctattat tggctagtct cattctttgc cttgcttctt ttctaccagc tgttgctgtg
     2041 caagctgaag atacgttcaa agtaaatgca aaagcagctt ttgctgtaga tgcgcaaagc
     2101 ggtaagattc tttatgatca agatggagaa aaaaccatgg ggatcgcttc aatcacaaaa
     2161 atcatcggtc tttacatcgt ccttgatcaa gtaaaagaag gaaaactgtc atggggtgat
     2221 aaagtttcga tttcagatta tgcagaaaat ttgagtatca ccccagattt atcgaatgtt
     2281 cctttgcata aagaaaacac ctacactgtc aaagaattat tcgactctgc aatcatccag
     2341 tcagccaatg cttcaatggt ggccttggca gaaaaaatct ctggcagcga agctaaattc
     2401 actgaacgaa tgaaagaaca attgaaagat tggggaatca aagatgcaac aatcgttaat
     2461 gcatcaggat tgaacaactc ttatcttggc gaaaaccgac cagaaggcac tggagaaaac
     2521 gacgaaaatc aaatgtctgc tcaagatgtg gccatcgttg cccgccattt gatcttggat
     2581 ttcccagaaa tactggatgt atcaagtact acgacccaaa tgtttggcga aaatacgcaa
     2641 tcaccagtgg aaatggtcaa ctggaactgg atgctcccag gattcgttaa ttacaaggaa
     2701 ggcgtggacg gattaaaaac tggtacgact gagcttgcag gtgcttgttt cgttggtacg
     2761 atcactaaaa acgatcaacg gatcatcact gtcgtattga atgcggacgg ccatgcggaa
     2821 aacccgagtg cccgcttcaa tgaaacagac cgtttgatgg actactgcta tgacaattgg
     2881 tcagaaaaag agctcggaaa agctaacgca agtattccta gtctaaaaac cattgatgta
     2941 aaagacggaa aagaatcaac agttcctgtt gtgcttaaaa gccctgtaaa agtatgggta
     3001 cgaaacgata tggatactgg caaattaacg atcacgccaa cacttgacaa gaagcaagtc
     3061 actgacaatg agatccaagc acctatggat aaaggtacaa aaatcggtac cgctacgatc
     3121 accttggcag acgataaatt aggctattta gaagacaaca atgcaccatc aacagagatc
     3181 attacggata aaacagtgga aaaagcgaat atattcgtga ttggctggcg acgcgtcgca
     3241 gaatttttcg gcaacttgtt ttaattgaac aataagaaaa acatctttcc atcggaaaga
     3301 tgtttttttg ctttttctag tttaaataac agcttttttc atctattttc gttatactgt
     3361 ataagaaaaa ggagttgaat ttatgaatct aaccagagat ctgatctttt tagttctcta
     3421 tcttattggg gtattctcta tcgtttattg gcgaaaacag aagaaggatc cttccttgtt
     3481 cttttacggc agtacgtgga catttacggt aatcttaact tattttgtcg tgttggaaat
     3541 tttttattcg accttttatt ttttgattcc attgttgttc tttagtatct ttgctttttc
     3601 ttatttcaca gaaaaacgaa ggctactgaa tggtctttta ttcaatgttt tactcatcag
     3661 tttcggcatc tacttgtttg tcttgctgta tgaaacgcaa aatatttttc ttggcggact
     3721 gatcgccttg atcacgattc cattgctact tgtcctttta tttggtattt atggattgat
     3781 tgtttttctt ttttggaacg gggtcacagt tttacgtaga gaatcgcatt cattagctaa
     3841 tcttttaacg ttgatactag ccatttttct tacactgttt cttgtttttg actttttctt
     3901 gttaaaatat ttgccgcaat ggataaatgc tttgtttttc tgcgttcccc tgatcttgat
     3961 ctatctattt atcgtattct acaacttttt gactgtctca ttcttgtatc agttcaaccg
     4021 gcctcgatac aatcaagact tcatcgttgt gttaggcgct ggattgatca atggagaaac
     4081 agtttctcct cttctagcca agcgaatcaa taaggcaatt gctttttatc gggctcaaag
     4141 ccgtgctaca ttaaatccgc ccatcttatt gatgtctggc gggcaaggag cagacgaaaa
     4201 agtaccagag gccattgcga tgaaacaata tgccatggaa caaggaatcc ctgaaagaga
     4261 cattcttgtc gaaaccaatt cgacaaccac tttggaaaac atgctctatt caaaggaaat
     4321 catggatcag caaatgaaag ggccataccg cgcgatcttt agttccaaca attaccacat
     4381 ttttagagcc ggtctttatg cgcggcaagc caaattgaaa gcaaatggta ttggtgcaaa
     4441 aacagctttc tactacttgc ctaatgcgtt tttaagagaa tacctcgcca tcttgatgat
     4501 gaacaaaaaa agacatatga tcatttgcgg attgcttttc gcaggctccg cattcttatc
     4561 gctgattact ttacttttct aaaaaaacaa ggtgtgacaa aacatatgtc acaccttgtt
     4621 tttttctttc attctcttaa ctattggcaa aaagagtatc ccttttttga ccgctacttg
     4681 ctgagcagaa taaataccgc tgttgcctga acacataaag ctgatcaagc agatcataaa
     4741 gaagtatact gccgcttgtg aaccgaacaa ttcgatcccc atcacaaagc aggcaatcgg
     4801 tgtatttgtc gcaccagaaa atactccgat aaagcccaat cctgcaagaa aaggaacaga
     4861 aacatggagc aaaggcgcta gtgctgcacc aagcgttgca ccaatttcaa acaatggtgt
     4921 cacttctccc ccttgatatc ccgcgcctaa agacaaaact gtgaagaata acttcccaat
     4981 aaaatcatag acatgtgcct gtccattaaa tgattcttga agtaacggaa gactcaatcc
     5041 gagataacgt tgtgtttgca aaatcaatgc tgctgccaca actacagctc cacctatcgt
     5101 atttcgacaa acaggatgag gaatccattg tgcatatcgc gcttttaaaa agacgatcga
     5161 acggctgaat acccaaccaa tcaaaccaaa agcaatccca gcaacaaaaa ctttgaagaa
     5221 cagcaacata ctccattcag gaatcacacc catttggtaa tgtagatgag aaacaccata
     5281 gctttctgtc atgaaatttg caaacagtgc agcaaagaag ctagggaaga tcgcttctgt
     5341 tcggactttc ccgattgcca acacttctaa tccaaataat gttccagcta aaggtgtgcc
     5401 aaatacagaa ctaaaacccg cactgattcc actgataatc aagatttccc gttctgattt
     5461 atccaatcgg aacaaacgtg ccgtattatc tgctaacgct ccccccattt ggactgctgt
     5521 tccttcacgg ccaacagatc ccccaaataa atgggtagtt atggttccaa acagtgtaag
     5581 tggaataagc cgcaacggga ttttttcttc tccaccattt ccttgatcga tcactaagtt
     5641 gtttccacga ctagaaagtc cgccgtgata cgcatagaga taagcaaaaa gcgcaccact
     5701 aactggtagt agacaaagga gccaaggatg tgatagtcgg atatctgtca caactgtcag
     5761 gctatttaag aaaaaagcag acaagctccc catgaatata ccgagaatcg ctgtgatcac
     5821 cagccacttc agcatataca ctaaaatgcg tactggactc ggtaattgtt tttccataaa
     5881 aaattcctcc tcaataaaaa aacgcct
//
LOCUS       DBBGSP010000111         5595 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000111 DBBGSP010000000
VERSION     DBBGSP010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.112"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            6..863
                     /locus_tag="ACIZE9_002987"
     CDS             6..863
                     /locus_tag="ACIZE9_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC6094786.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            885..1394
                     /locus_tag="ACIZE9_002988"
     CDS             885..1394
                     /locus_tag="ACIZE9_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HGC6094787.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            1431..1832
                     /locus_tag="ACIZE9_002989"
     CDS             1431..1832
                     /locus_tag="ACIZE9_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094788.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            1944..2297
                     /locus_tag="ACIZE9_002990"
     CDS             1944..2297
                     /locus_tag="ACIZE9_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094789.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            2331..2774
                     /locus_tag="ACIZE9_002991"
     CDS             2331..2774
                     /locus_tag="ACIZE9_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC6094790.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            2791..3876
                     /gene="uxuA"
                     /locus_tag="ACIZE9_002992"
     CDS             2791..3876
                     /gene="uxuA"
                     /locus_tag="ACIZE9_002992"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HGC6094791.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            3869..4582
                     /locus_tag="ACIZE9_002993"
     CDS             3869..4582
                     /locus_tag="ACIZE9_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC6094792.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(4789..4938)
                     /locus_tag="ACIZE9_002994"
     CDS             complement(4789..4938)
                     /locus_tag="ACIZE9_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094793.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            5334..5534
                     /locus_tag="ACIZE9_002995"
     CDS             5334..5534
                     /locus_tag="ACIZE9_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC6094794.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         1941 a          856 c         1216 g         1582 t
ORIGIN      
        1 gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag
       61 atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac
      121 gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag
      181 atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa
      241 gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag
      301 aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg
      361 gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata
      421 tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc
      481 cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt
      541 tcactatggg ccgtaatgct acaggcctaa tgcaaaacac tggtgttcag acagcgattg
      601 aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag
      661 tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg
      721 atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata
      781 cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc
      841 tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt
      901 tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa
      961 gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag
     1021 atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga
     1081 aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa
     1141 aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata
     1201 ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt
     1261 taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata
     1321 tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt
     1381 ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga
     1441 acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa
     1501 aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag
     1561 atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag
     1621 atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag
     1681 gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat
     1741 tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc
     1801 ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga
     1861 gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc
     1921 gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg
     1981 tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat
     2041 cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc
     2101 tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt
     2161 tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct
     2221 atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta
     2281 ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa
     2341 tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg
     2401 tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat
     2461 tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat
     2521 ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga
     2581 ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag
     2641 aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca
     2701 aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg
     2761 aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa
     2821 aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt
     2881 ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg
     2941 aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac
     3001 gatgcaatca aggcagggac agatgaacga gattactata ttgataacta tatacgaaca
     3061 atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt
     3121 ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac
     3181 gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag
     3241 tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg
     3301 gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta
     3361 gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat
     3421 ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa
     3481 attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg
     3541 gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt
     3601 gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc
     3661 tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc
     3721 gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga
     3781 tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata
     3841 agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat
     3901 ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca
     3961 aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat
     4021 ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg
     4081 agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa
     4141 aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc
     4201 ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt
     4261 gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt
     4321 tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc
     4381 gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca
     4441 tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata
     4501 tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga
     4561 aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc
     4621 ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt
     4681 atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat
     4741 gcgtttaaag agaagaacga gaatcgtcca tatgagggtt tccactcctt atgcagattt
     4801 ttttaattct tgcactgctt gttcgatcgt aacacctgtc gctacatgat tggtattttc
     4861 tttgtcaaaa acgacaaata gattcaaatc tgtatccaag gttactcgat attgtatatc
     4921 tttgttatag aatgtcatag ccattctcct ttctttaaat acttgctgaa aggcaacgaa
     4981 cgcgttgata acgaaattcc atttataagt ataccaccaa ttgaaaggtt ttcatagtta
     5041 agaaatttta aagtcaaaag ttgcagataa aagcaaataa acaagaaaac aaaaagtgaa
     5101 tcaatcgcgg ttattcaact ttttcttcga ttcgaagaca atagaagaca atgaatttta
     5161 tatttcattg cattatcctt gtgttattag aaaaagcatg atatattaaa tgagtaatct
     5221 attttgaaac gtaatttgag cgatatatct acatagataa aactcctttt gcctatcaaa
     5281 tatttattgc aacgaaaaaa cgtacattga tacgtatcag gaggaattta tttatgaata
     5341 acggtacagt aaaatggttc aacgcagaca aaggttttgg ctttatcact ggtgaagatg
     5401 gaaatgatgt atttgcacat ttttcagcta tccaaggtga cggcttcaaa actttagaag
     5461 aaggccaagc agtgtcttac gatgttgaag atggtcaacg tggccctcaa gcaacaaaca
     5521 ttgttaaagc ttaataaaaa ttgactttta accgtctttt cgaaagaaaa gacggttttt
     5581 ttgtacgaaa aaatt
//
LOCUS       DBBGSP010000112         5340 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000112 DBBGSP010000000
VERSION     DBBGSP010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.113"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(61..285)
                     /locus_tag="ACIZE9_002996"
                     /pseudo
     CDS             complement(61..285)
                     /locus_tag="ACIZE9_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(839..925)
                     /locus_tag="ACIZE9_002997"
                     /pseudo
     CDS             complement(839..925)
                     /locus_tag="ACIZE9_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2091..3131
                     /locus_tag="ACIZE9_002998"
     CDS             2091..3131
                     /locus_tag="ACIZE9_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HGC6094795.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3955..4287
                     /gene="traE"
                     /locus_tag="ACIZE9_002999"
     CDS             3955..4287
                     /gene="traE"
                     /locus_tag="ACIZE9_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HGC6094796.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4906..5247
                     /locus_tag="ACIZE9_003000"
     CDS             4906..5247
                     /locus_tag="ACIZE9_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HGC6094797.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1943 a          728 c          900 g         1769 t
ORIGIN      
        1 aggtattttt attatatata gatttaacat atgtcggtcg gttgattgat atagctaaag
       61 ttataactca accgaagccg attcatctac acgaataaag ttgcgagtgt tctcggctaa
      121 ttcataaaaa ttgttatgtg ttccatatag caatactgga ataactttat tttcttgaat
      181 ctcataagca actctataca cggtgaccgc atacttaaat ccattagacc aattacctga
      241 taaacctcca gttttttgct cttacttaaa tggatcaatg gcaatttcat cacaaaccta
      301 tagaggatga gtgacttctg cctaattacg ttaaaaaata ttgaaagtaa ctctatgtag
      361 caaaaaatat ctagaatttc atttcctcaa aactgatcga tattgtatct aaaaatatat
      421 actacctaaa ataggtagta tatattaaaa tatgtgcttt tgttagaaaa atcaatacat
      481 aaattatcat atctgtatat gtcatttagg tatttcagtt atgttataat agttttgctg
      541 tctgctaccc cggcctaatc tggcaagggg aggaggagat ataatgaaat acctttttga
      601 ttttgttttt gcaatcaagc cacttgcaga tgtagtgtgc agttacctct gcaaatggct
      661 tgattgcaaa attgccaaaa aagacagtaa gcctacccgt taattctata atatagaaac
      721 gtaaaaaaaa ccccatcagc ctgcacgctg atggggtttg gtgatataat gaaatacctc
      781 tttgttactc ataattatac cataattagt cacgaatgca accaatagaa aaaactactt
      841 agaacggtag atcatcgcta ataacaatgc attgtccacc aaatggattt tgtgaagcat
      901 taaatacatt gttattaatt gtcgctgctt ttaactaggc ctctcccctt ctattataaa
      961 agaagatata tatcatttct taattaccta ctaccttaaa ccaaaattta agtactacct
     1021 aatttaagta gtacttaaac aatctaaaaa atagttatcc caattgttat gcttttataa
     1081 tacgattatt tgtaacaaaa tgaatattat ataattaaac actaccatat ttaggtagtg
     1141 tttaattatt agcaaaacaa aaaatattta ttctattctc ttaacttcaa ctaagttatg
     1201 ctgcacacct ttatataaat catatgcaac tcattagcta gacaaactac aagcatgtag
     1261 ttttatctgt taattatgta ctacctaaat aaagtagttt ataattagca agtatatata
     1321 tttaaaaatt taagattaat ttttttatga cttgtacaaa tttatctgat attctcttat
     1381 taagaactac ctaatttggg tagttcttat tttttacatt ttaagtagta tttaattgca
     1441 atttggtagt atttttttat tatcttattc ttagaacggt agtacttaat ataaatatag
     1501 gtagtatcta atttaagtat taatggtagt atctaaatta acaggtagta tgtaactact
     1561 ttaaagtaat ttttttcaga ttaacacagt agtatcttat taaataagtt aattttaatg
     1621 gtagtacata attattatat atatctgaca ttggtagtac ttattgtatt ttttagtagt
     1681 atataatcta ttgttttcta gcctaaagcc ttgtcttata agaataatat aatatatact
     1741 actgaaataa ggtagtatat attactagta atggtagtat gttttatatg cataaggtag
     1801 ttcttaattt attttttgtt ttgacactgg tagtacttaa ttatctttaa ttttaaaact
     1861 aaattttatt catacgtttt tctggtagta tttaattata aataatattt atttaaagta
     1921 gttcttaatg actttaaagg tagtacataa ttcattttat ttctgatttt aggtagtatt
     1981 taattaaaaa acagttttaa tgcgtttgca ttttttattt atctttgcta ttttcgaaaa
     2041 gagtaggtaa ttttacataa ataaaacaac gtgaaagtag aggatctaca atgactgatt
     2101 ttaaattttt taaggcggat agagtttaca acgaattatt ttatcaattt ccaaaagtct
     2161 ttattgtttc tgacgaatac aaaaaaatga aagattcaac taagattgcc tatatgcttt
     2221 taaaagcaag attagagatc gcaatcagca aacggcaaat cgatgaagaa ggtaatgttt
     2281 attttactta tacgacaaat gaactatgta gagtattaaa ctgccaaaaa caaaaagcga
     2341 tagcaatcaa aaaagagttg gaatcctttg gtttattatt acaaaagcag atgggattta
     2401 acaaacagtt agggaaaaat aatcctaata gactatatct agcagaatta aaagtctcag
     2461 aaaatgatat ctacttactc gaaaaatttg atagagagaa tagggaaaac gttgataaat
     2521 cagagggtat gaaaatcata cccaccctcg acgaaaaatc agacgctgaa tcccttgggg
     2581 ctcaagaggg tatgaaaatc ataccgtgcc aaaacgttga taaatcagag ggtatgaaaa
     2641 tcataccaga acttaataat aatatattag acactaatag acacaatata gacactgaaa
     2701 aagaccgcct acaagatcaa ttgttgttag acaattttga gacaattatg acaaacgaca
     2761 gcattgctac gtttgtccct gaacgagtat taaatttgat aaaaacattt tcttcaagtt
     2821 acagtgaagc tcaaaaaacc gtccagacta ttcataatgc aaagaaaaaa gctgaaatag
     2881 aaagtgatat ttcgatagtt tttgaagaac tcgatagtta ttatgtcaat gcagaacaag
     2941 aattatacac gacactgtta aaagcctatc aaaaattaaa aaccgaaaaa gtcgaaaata
     3001 tccagaacct gatttttgtc tatgtaaaaa attggtttat cgaaaaacca atagctgcta
     3061 aagtatcaag tgaaaaacgt ttgaattatg caagctcccc aagcactatt acgaaagact
     3121 ggttagagtg aaactttact gacaaagtga ttgttgcttc atggagtaac attaaaatta
     3181 aaaatttttt attattctaa ttatattacg aatattacaa aataatagct attttaatag
     3241 aatttataag ttaaaatatt atgataaaaa tcacaaacgt agccttttac gtcataagtg
     3301 ttaaaagaaa taattaattt caaatataga aaagggaacg tatgtttgca tactcctttt
     3361 ttttgagtta taataatacg cgaagagaga taatttcatt atttaaacaa gctaaaaatc
     3421 ttgatattac ttcttttcag gcaatacgaa tattattcgc ttacattttt tgtataaatt
     3481 taattgtctg ctatgcttgt gatgaattga ttttcgtttt gcacttttgg atgataaatt
     3541 tggacaattg aaaatacaaa aaaaagaaag gcggtatgaa ctcggaaggc tggtaacctt
     3601 cgtcagcgtt catacacggc attaagattt ggcccttaat gcgttaacct ttcagtgtta
     3661 cggtattacc cgcaatggat ttagtataac agatattcaa aagtgatacc actttttttg
     3721 gctgtgttaa ggttaaaaat acgtgatatt acgatgaatc tatgcctaag cataatgtta
     3781 taaaaatgtc cgtgtggctc tttgccgtat gacgaacgct gaaattagag ggaacgcatg
     3841 tttggatgcg ttccctcttt tttgtttgtc atgaacgaaa atcaattctc tatttttgaa
     3901 aaataacaag aaaaacttgt taaaaatatt taaagaaatt gggtggttta ttttatgtca
     3961 tatacaggaa ttttgagtct caaagatatt tgtcactacg gtaaacggtg taccgctaca
     4021 gagaaaatca cgaagaaact atcaactggc caaagtaaaa ccgttgtgca gtgtaagaaa
     4081 tatataatcc agaaagacaa agtctcagag gaaatgattt attacattgg gaaacaaaag
     4141 caaataattt taaaagatcc tatcccctta aaagagctat atccaacaat caaacatgtt
     4201 tatgaccaaa acggtgtact gattggtcga agaaaaaatg gagtcttgcg ttgtaccgca
     4261 aaagggatgg ggcgtttgat cggctgaatt gatcattctc ataacttgta ttttatcgtt
     4321 tttcgcttgc ttgaaaatat tgtcgagact tctaaaggaa cttagagtca ctagaaaaat
     4381 aaggagtaga cttgatctat caacaattcc cttcggggag tgacggggta ggttttaacg
     4441 attggtaacg taaaaaattg gtcaatcgag taaatgcgct tgtttggata gtggtgaaat
     4501 gaatttgtgt aaataataag cgcagagtaa acaagaggga atttagaagt tagacaagtt
     4561 agaatagcgt ctagattaat catgagcagc tactaaggga tctagacttt gacgcaaact
     4621 catggaataa ggagtaggtc ttctcgtaat ggggaggacg cacaagaaat tgtgtcgtgt
     4681 gctgcagtac atgtagatac ttgcgaggac gttgattatt ggatcaatcg agcatttacc
     4741 gctgtctact agggtttctc gtttcggacg ccataaacga gtcgaaattt tttatgtatt
     4801 tttaagtaaa cgaaaaacga taaaatatga acaagtcctg aataaagtga aaaaattgat
     4861 ataaaacata gagaaaatga aatttacgta atggaggaat gacaaatgaa aaattatgat
     4921 ccgaatatac gattgggcac acatactatt aaggtttctt tccaacgttg ggattacaaa
     4981 ggatttgtga cgtttagaag gggcggaaat tgtaaaggat tagatgtttt agcattagac
     5041 gaggatgatt tatacgatca aacattgact gataatccaa ttggattcgg cttgctacct
     5101 gaagatgatg aaggtaatga atggtttaaa atgacgctta tgaatgataa tggagacgaa
     5161 ttatctgttg aagatacttg gtcatatttg agtgattata ttgtcagctt tgaaatcatt
     5221 gaatttgtag cggataaaga agaataaaaa ctggaggaat aaattttaca gataaaggct
     5281 tagaaggagt cacgacgatt aataaaaagg tagtattacc ttaggcattg agtaaggaat
//
LOCUS       DBBGSP010000113         5312 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000113 DBBGSP010000000
VERSION     DBBGSP010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.114"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(74..1222)
                     /gene="nagA"
                     /locus_tag="ACIZE9_003001"
     CDS             complement(74..1222)
                     /gene="nagA"
                     /locus_tag="ACIZE9_003001"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGC6094798.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1298..2134)
                     /locus_tag="ACIZE9_003002"
     CDS             complement(1298..2134)
                     /locus_tag="ACIZE9_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094799.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2318..3535)
                     /locus_tag="ACIZE9_003003"
     CDS             complement(2318..3535)
                     /locus_tag="ACIZE9_003003"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGC6094800.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3684..3845)
                     /locus_tag="ACIZE9_003004"
     CDS             complement(3684..3845)
                     /locus_tag="ACIZE9_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094801.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            3918..4001
                     /locus_tag="ACIZE9_003005"
     tRNA            3918..4001
                     /locus_tag="ACIZE9_003005"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3952..3954,aa:Leu,seq:gag)
     gene            complement(4241..5312)
                     /locus_tag="ACIZE9_003006"
                     /pseudo
     CDS             complement(4241..5312)
                     /locus_tag="ACIZE9_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1082 c          838 g         1739 t
ORIGIN      
        1 tttttactag aacacaaaaa aaaccttaaa accaaactta agaagtttag ttttaaggtt
       61 aacttaaatt atattatgcg tggaaacgtt ccacgccatc tagataagtt gcttccaatg
      121 tcatatcagg gttcaatacg ataaagtctg catcgcgtcc ttgagcgatt tttccacatg
      181 tatcatcgat tttacagctg attgctggaa tcagactagc catcatgact gcttgttctg
      241 gtgttgctaa tccccagtct acaacatttt taattgcttc tttcaatttc aatatacttc
      301 cagctaagtt gccagattct agacgtgctg ttccttcttt tactactact ggaaattcgc
      361 ctaaattgta atttccatca ggcatcccac cggccatcat acagtctgta attaatgcga
      421 catgatcatg tcctgctttt tccattagga ttcccgcagc atttggatgt acatgatggc
      481 catcacaaat caattcagaa aagacatgtt ctaaagataa taacgcaccc accatacctg
      541 gttcgcgatg attcaatcca cgcataccat tgaaagcatg gacaaataca cttgcgcctg
      601 cttcaacagc tttttgcgct tcttctagtg tagcattact gtgtcctaga gaaacaacta
      661 ctccttcttc agtcacttgt ttgacaaact cttctacacc ttgacgttcc ggtgctaaag
      721 caattttttt gattaaacca cctgaagctt cttgccattc atggaaagta tccaaatcag
      781 gatccccgaa ataacttggg ttttgtgccc ctttgtgttc ttctgtgaag aaaggacctt
      841 caaaatagat tcctttgatt ttagctcctg gtgcttcctg atacattttg ccgattgtct
      901 cagctacatc ttttaaacgt tctttgcttg acgtcaatgt tgttggtaaa aatgaagtca
      961 ctccacaaga taacagacct tcagacatca ctttgatgcc ttctgcatca ttatccatta
     1021 catcatgatt catatagccg tgaatatgtg tatctaccaa accaggagca atccatttgc
     1081 cgctttggtc aatgatgttg acttctccct caggtagttc tttggtgtat tcaccaaaaa
     1141 gtccatcggt aatttcaaga tagcctgcat gtttgacacc tgacgctaaa aagaatttgt
     1201 cagcatagat aaaagttctc attctattct ctccctttgt ttttctacct ctaaagtact
     1261 cttatttaga gaagaagtca agaatggtct acaccattta caaatttttt gaaatttgtt
     1321 tcacagcttg tgctaagcct tcatagaatg ctgctctttc tggttcttct ttacgcttgt
     1381 atattaagct tttaagcaca aataaatcat tgaggtaata gtagctattc ttctcttgag
     1441 cccaatagat tccttgattc acctgttcta acgcttcgtc gatttcattt tgatggaata
     1501 agaaatttcc ataattataa aaaatttgcg aaaattcact ttttgatcgt tcatcagctg
     1561 attgatgcag cagttggatg cttcgactca aatagtagcg tgcttcagcc gtttttcctg
     1621 ccacaccata tatttttccg atacaactaa tcagttgtat ttctgtgtca gaaacatgga
     1681 ttctttcttt ttggctagag tagcttaatg cttctttcaa ataataaagg gactgagaga
     1741 tattttgacg caacgtgaat tcgcaaacac cgagataata ataatagcgt tgaaagtcag
     1801 ttgcttgata cagattttca gaaatatcag aagattttag tacttgttct aacttccgat
     1861 aatcacgttt ttggaaacaa ctatccaaca gttcaaataa tttatcgttt gtccgagtag
     1921 tttttcgaga gagattcatc acatgatcaa tcgttacccc tagccgttga caaatctgca
     1981 tcatcaccaa tacattcggc agttcctcat tattttcgat ccgacttaat acactttgtg
     2041 aacaaatatc atgcgaaagc attttttgcg tcattttttg ttcttttcga atctctttaa
     2101 tgatcgttcc aaaggactcg attaacgttt ccataagtat cctccccaaa atatgcgtat
     2161 tcgcattcta ttcgtatttt actttaggaa gtcgcaaact tcaagaaaag acttgcaact
     2221 aaataatata ctttagttat ttaagaaaac tccactagaa agagagcctc agtgtgtttg
     2281 tctgtggccc tcctactgaa aaatttggtt tttaaaatca tttttggcga taggttgcta
     2341 ggaattctct cattttctta gctgtttgtt tcaaatcatc cattttagga agataaacga
     2401 ttcgaaaatg atctggctgg ttccaattaa atccaccacc atgtacaagt agaatatgat
     2461 gttcatgtaa aaagtccaaa acgaattttt catcatccaa aatattgaat cgctttgtat
     2521 caatttttgg gaatatataa aaagcagctt ttggttttac ggctgaaaga ccaggaatat
     2581 cattgattgc attatagata tattctcttt gttcatagat ccttccgcct ggcaggagca
     2641 gctcatcgac actttgataa ccgcctagcg cggtttggat aatttgctga gacaatacat
     2701 tggaacacaa acgcatggag gacaacatat tcagcccttc tatatagcct ttgacgtgtg
     2761 acttatctcc acttaggacc atccagccta ctcgaaatcc tgctacacga tgagatttgg
     2821 atagaccgtt cagcgtaaca acgaacaaat caggcgctaa tgtagcaatc ggaatatgtt
     2881 ctagaccatc catcactaag cgatcataga tttcgtcgga ataaataatc aggttatttt
     2941 gtcgagctac ttcaacgatt tcttctaata attcttttgg ataaagtgcc ccagtaggat
     3001 tattaggatt aatgataaca atagcttttg tccgactcgt tatttttgat ttgatatcat
     3061 caatatcagg ataccattct gcctcttcat cgcaaatata atgaacaggt gtgcctccag
     3121 ctaatgcaat agaagccgtc cacaacggat agtccggcat tggaaccagt acttcatctc
     3181 cattgtccag caacccctgc atacacatcg tgatcaattc gctcactccg ttgccggtgt
     3241 agatatcatt gatcgtcaca ttcggaaaat gtttcagttg gcaatattgc tcaattgctt
     3301 ttctagcaga aaagatcccc ttggaatctg agtagccttc tgagtcacgg gcattcatga
     3361 tcaaatcacg aatgacttcg tttggtgctt caaatccaaa aggtgcggga tttcccgtgt
     3421 tcaattttaa aatactaatg ccctcttctt gcatccgctc cgcttcttct agaacgggac
     3481 cgcgaacatc gtaactgaca ccttctaatt tgttggattt ttcaaattct ctcatcactt
     3541 agccaatccc tcatttcaaa aagttagaac tttccaaatt ttttgttatt tactatttca
     3601 atatcatact ccatcctaga aaattttgcc acttatttag gaaaaacgta agtattaaaa
     3661 aaacacaaac aagcgttgag aacttaattg tcatgatagt cattccatag attcgctgcc
     3721 caatccattg caattccaca aatgattcct agcataaaac caagcaaaaa acgtccgaat
     3781 gcaagtccaa tcaatacacc taagatcatt cccagtcctg aaaattctcc gtcatatttc
     3841 tccatcttaa taagtcctcc catttttgag cttgacaact atgtaaaacc tcgctatcat
     3901 tagtgtgtta ttattacgca gatgtgttgg aattggcaga caagcatgat tgagggtcat
     3961 gtgagcgtta gctcgtgtgg gttcgagtcc catcatctgc actacaactc gtgaagttaa
     4021 ttttgcttca cgagtttttt tgtttgaacg tttctttatg ccattatata catatcactg
     4081 tatcctttac aaaaagaacg tacaatcatg taaacagcct gaggtgagta tatgaaggtc
     4141 ggaaacaagc tactcgtaga aacttgcaag tgttaaaaca attaatcgaa aaacgagtaa
     4201 aatccctcac ctaatactaa agcgagggat tttttgtata ttatctgttt atcaccgtta
     4261 ttataaaggt acaaatacca agcacggtta atccaaattg cataaattca tttttttgta
     4321 cactcatgct tttcattagc tctttaactg ccattagtac taagatggcg ataacaacat
     4381 aaagtatata gtacgtccgc attccggaag cccatactgt gggagaaaat cccataatta
     4441 accttgaaca aaatcccatt atcatcaaaa taactaaaaa aatagaagtt ttcttattgt
     4501 caaaacttaa ataaattcca acaattaaac atagtaataa tgccaagact actaaagtag
     4561 ctatccaagt acctggataa aaaagtgaca gtttcgttcc taactctgta aagagattat
     4621 tcaggttact actactccaa atcattgccc ttttatttcc attgacgtaa gtaaagcttt
     4681 gacccattgt attaccaaaa taaataatca ggtttaagaa aaacggtaat gcagtcaata
     4741 tacgcacata atagttttga catttcctat atgttagaag gaaaattaag aaaaatagca
     4801 ataaaaataa gatattcatg tctaaaaaaa cggctttcca aatgatgaaa tacctaaatc
     4861 taacttatta agaaagttga aatttttata ttcaggaaac catttattaa tttcatgtgc
     4921 agcacgtaat gcattccctg gagttgtcaa agagaaaatt aattctgcta agcttattat
     4981 tgaaaatact gataacttat aattatatcg tccattgaca atcaaatata aactaactat
     5041 acttgttaga acaaaaaaac aggcgttgac ttgttcttga ttagttaaaa atatcaataa
     5101 aggaatactt acccaatata tttttctatt tatttcttct cctcttaaga gttgaaaaaa
     5161 cggataaaaa gttagtaaac taaatgctac tggccactga tagttcaagg tggttgctct
     5221 ccaaccggtt tcccccatta ctgtcaatgg tattaaacag tatatagagc aaaccaataa
     5281 taaattttta acatttattt tctcaaaaac at
//
LOCUS       DBBGSP010000114         5304 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000114 DBBGSP010000000
VERSION     DBBGSP010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5304
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.115"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            447..1175
                     /locus_tag="ACIZE9_003007"
     CDS             447..1175
                     /locus_tag="ACIZE9_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HGC6094802.1"
                     /translation="MKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEAG
                     DEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYAA
                     ADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAVS
                     LVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSVP
                     GKSVKLAQQYSTKLVWTLEDTPNN"
     gene            1320..3347
                     /locus_tag="ACIZE9_003008"
     CDS             1320..3347
                     /locus_tag="ACIZE9_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGC6094803.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            3455..4552
                     /locus_tag="ACIZE9_003009"
     CDS             3455..4552
                     /locus_tag="ACIZE9_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HGC6094804.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            4859..>5304
                     /locus_tag="ACIZE9_003010"
     CDS             4859..>5304
                     /locus_tag="ACIZE9_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094805.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT         1886 a          829 c         1070 g         1519 t
ORIGIN      
        1 tcgtggatat gctgcttttt ttgcggaaaa taatcagcga atgtttattt gatcggatga
       61 tttgtaactc gcagagtact agatgcaagc gtgtattctt tttttgaacg ataatcacaa
      121 aaaaaaatat aatatacatt ttttatttaa ttataattaa tattgattga agtctaggca
      181 gtcaagtcac attttgatag ataggagggg gacttacgaa ttattttaaa ggctatgaca
      241 gctgtatttc tagattgtgt ttgcatcaag ttgcaataaa aactagaaat caaatcgggc
      301 tgataatcat ttataactaa tcgatacata ggaccaaata taggtctatg ttcttttatt
      361 tcataagtat cgtaaaacag aattttgcta tggattaatc caatcgactg atatgtttag
      421 taaataaaga aagaggaatg tcaatgatga aaaaagaaat cgtattaaca gcagcaatga
      481 tgttattcag catggtagca agtacgactt ttgtttctgc aactgaagta tacccaaagg
      541 aatataacac agaaggaacg attacatttg aagcaggaga tgagggtgta actcctcctg
      601 ttgatccaga gaatcctgat cccaataaac ctgtcgatcc atcagatcct ccaagccctg
      661 gaacaggagg ggcattatcg attgattatg gatcaaaatt caaatttggg actcaaaaaa
      721 tttctactgc ggataaaacg tattatgcag ctgctgatgt gatgaacgat gggtctagaa
      781 aaccgacata tgtccaagtg acagatagga gaagtacctt atctgggtgg aaattaagtg
      841 tctctcaacc agaacagttt aaaactgcca gtggggatga actagttgga gcacagctga
      901 aatttacgaa agggcaggct gtttctttgg ttgatccaac atatacgccg caaacggtga
      961 attctgaatt aacgttgaca ccgggaggaa acaatacgtt agcaattaat gctaaatcag
     1021 gaacaggtgt ggggacttgg gtctatcgat ttggtgcaaa tgaaaatgaa aatcaagatg
     1081 cggtacagct ttcggtaccc ggtaaatctg tcaagttagc gcaacaatat tccactaaat
     1141 tagtttggac attagaagat acacctaaca actagtttac tgaaaagaac tgttaaaaat
     1201 aaatacgtag tcatattgtc ttgcgaggta atcgagcaaa aattgtcaaa ggctaggcta
     1261 aatttgtttg gatacgaata gttcatctag gaatttaacg atcaggagga aaagatatat
     1321 tgaaaaagag gaggatcgtg ctcattttaa gcagtctctt agtgactaat atctttccga
     1381 tcatagggta ctctttggaa ttgaatcagt tggagcatgg aaatagaaga gacgaagaaa
     1441 gcaaactcac ttcgacattc gacagtttaa tagaatccaa ccagacacaa gaaagcagtg
     1501 aggatttaag tatttcgagt agtggagaga ccactgacaa cgtagaagct gagggttcgg
     1561 acaaacaagg actagaagat gcaccaattt ctgcggttga gctgcctgac gatcccaata
     1621 ttatttctat cgataaaatt tttcaaacac ctatcggtac tagcacgtcc atattggaaa
     1681 atgggaagtt actgcagttg aacccagcag aaaggtctca aagaggagct atttggtcaa
     1741 ataagaagat tagtttactc tcggatttta catttaaatc ttatttatac ttaggaaatc
     1801 aacgagatag agcgggagat ggcatgacct ttacattgac tggcgatcct agaatggcta
     1861 gtaatcccag tcaagttatt ggatcgccag gtatgggaat tggctcatat tctactcgtt
     1921 ctggccaacc ttacattgcg aatgcgctct cgattgagtt tgatacgtat aaaaatagtg
     1981 gttcttctga tcgaatggat cgagagataa ctgctgataa tagagggcat ggacatgtcg
     2041 cttttgtcac gcctaaacca aataataata attattctgg agagcatact ggcgtgacgg
     2101 tagctcctac atttctttct aatggcacat ggcgcttgtt aataattaaa tgggacgcgg
     2161 agcaaagaag tcttacttat gatttggaag gtgtcggtcg ctcttctcgg attatacctg
     2221 atctcattag gcagtttggt tctacagaag taaattgggg gtttacttct tcaacaggta
     2281 ctttttttca agaaaatgct gtcgctgtca cgcgacttcc atcgaatgtc acatcaacag
     2341 ctgatgtaaa agtcaacgat agtgattatg gggccatcgc tgaagctgga ggaaacgata
     2401 agataactat cagaaataca ttgaaggtcg agggggattt tcttgaatat aagaaaatgc
     2461 agactagtat cgacctccca caagaattaa ctattcccga gcatatcttg atcaatggaa
     2521 atcaaattga tgccaaagat atcttgataa ccggaaatcg agtcacgcta aatctgacag
     2581 attattttat tgctggagat acgttaataa tcgaattgga gacaactttg caggaagtaa
     2641 ttcctgaaaa agtactcact atgcattttg aataccttga aaacgggaat ttgattgagc
     2701 aatcgaatga aataaaccta aagatcgcaa agctgaagga gatagatatc catgtttatt
     2761 ataaagataa agacagtcag attgatattg ctgaaatgaa aacaatcact gggaaaatag
     2821 gagagaagta taaagaaact cctattgata ttgaagggta tgtttttgac tcggattcag
     2881 cgaatacaga aggcatcttc tccgaaaata cagaggatat ctatttttat tacagaaaag
     2941 gcaaacttta tctctcaact gctcctcaat atgtcaattt tggaaaacat aaaatatcca
     3001 gtagaccatt aagtgaattc ggacagtttt caggtgggtt gaaaattata gatgaacggg
     3061 cttttggaag ttggaaatta caattgaaac aagagaaagt tcttacaaat ggagattttg
     3121 agcttccaga agctctttcc tttgttacct ctgaaaatac aacggttata gggacatccg
     3181 ctgttacgat tttcgaaagt gatcaaaagg gtgaaagcga tttgtcctct cttttagatt
     3241 ctacagctca tcgtggaatc agaataaata ttcctgtaga aaaccaaaga atcggaacct
     3301 ttgaggggaa actatcttgg atacttgcag atgtcccagg aaattaacag gaagagaaga
     3361 atataacaaa attattgagt ttcaagaagg gcacaggtac cataggctct tgtgtcccac
     3421 agagacaaga ttttgttata gtcttctctt acatatgatt aaaggagcga ttttcttgag
     3481 accaaaacaa caattattta taacactcct agttatttta ggggcacttt ttaacaatat
     3541 atcagtgtca gctagtgcat ttaatttttc agtgacgccg ataacttcag agaatcaaat
     3601 cgacaagaga aaaacttact tcgatcttca acttgatccg gatcaggaag tagaagtaaa
     3661 agcggaattg agaaatgata cagaaaaaga agtgaaaatc gatatttctg tgaatagcgc
     3721 aaccaccaat tcaaatgtga tggttgaata cggaaaaaac gagattgaaa aagacatgag
     3781 cctgatcttt gatctggtag attatgtgag ctatccacag atagtgacgc taaaacctaa
     3841 aagtgtccaa accgttgctt ttcatgtcag gatgccgaat gagcgatttg atggtgtatt
     3901 ggctggtggg atcacattcc aagaaatcca gacggaaaag gaccaaacag aaactaagga
     3961 tcaaagctta tcgattgaga atgaatacac ctatattatt gctttgttga tgcaacagac
     4021 actgaacgaa gttgctccga accttactct tcatgaagtt aaaccagatc aaatcaatgc
     4081 aagaaatgtc atcttagcaa acgttcaaaa tgatcaaaaa acctatatca atcaagtagt
     4141 tattgaaaca aaaattacaa aaaaaggaca ttctgaagtt ttatatcaag aggaaaaaga
     4201 aggattgcag attgcgccga atacaaattt ttcttttcca actgctttaa atggtcaacc
     4261 gctaacccca ggtgaatatc accttacaat gactgtttta ggaaatgaaa atgaaaatgg
     4321 aaaattttcg agaaaaaaag gaaatactac gatcaactat accaatcaat gggtatttga
     4381 aaaagatttt acaatagacg gaaaagtagc caaggaattg aacacgacgg atgttacgat
     4441 taaaaaagac aataattgga tttatatctt agtagcttca cttttcttat tgtttatttt
     4501 attatgcata cttttgtttg ttttgagaaa aaaagaagag aaagaaaagt aaggttaaga
     4561 taacaaatag taaattttta ttattgtagg atggttgggc tctttttata acaatataaa
     4621 atataccatt ttattaataa aaatgcatac tagtaaatga tataattcta ataacaggtt
     4681 tgatcgcgag aaaggccaaa taaaacgctc tccaaaatgt taaaaaaaag acaggacgat
     4741 gtatattata caaacaagaa tcgctgacaa cagtgactcg gatccaggaa atcagtttta
     4801 tccccagcta gttggtgaat gcatggaaag taatatacgt agaaagagct gatgactaat
     4861 gaattatgag ttttttttaa gcaaagaaga tcacagaagt tattcattac ttaaatattt
     4921 agaagcaagc tcaaatttat cagagtcaat atcgaatgtt caagaagagt tgtcgctatc
     4981 gacatttctc ttgaaaaaaa cgatcgataa gctgaaacat gatttacaaa agttcgatct
     5041 agagaaaaat ttgcgagtaa ccgtcagtga attggatata tgtctggaaa ttaatggaaa
     5101 atgttctagc aaagctctgt tatctcgtta tataacggat tctttatcta tgaaaatggt
     5161 attggctttc tttcaggaaa aatatatctc agtagaaaat tttgctaaac agcatcacgt
     5221 gagttattct gtggcttata aagtattaca aagactaaaa agaaatctaa aaaaatatca
     5281 aatttttttt gaaaagagaa agtt
//
LOCUS       DBBGSP010000115         5024 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000115 DBBGSP010000000
VERSION     DBBGSP010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.116"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            282..521
                     /locus_tag="ACIZE9_003011"
     CDS             282..521
                     /locus_tag="ACIZE9_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094806.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(883..1143)
                     /locus_tag="ACIZE9_003012"
     CDS             complement(883..1143)
                     /locus_tag="ACIZE9_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094807.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1328..1825)
                     /locus_tag="ACIZE9_003013"
     CDS             complement(1328..1825)
                     /locus_tag="ACIZE9_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGC6094808.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1955..2665)
                     /gene="budA"
                     /locus_tag="ACIZE9_003014"
     CDS             complement(1955..2665)
                     /gene="budA"
                     /locus_tag="ACIZE9_003014"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGC6094809.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="ACIZE9_003015"
     CDS             complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="ACIZE9_003015"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HGC6094810.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4547..>5024)
                     /locus_tag="ACIZE9_003016"
     CDS             complement(4547..>5024)
                     /locus_tag="ACIZE9_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGC6094811.1"
                     /translation="CIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIV
                     SVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAF
                     YYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
BASE COUNT         1529 a         1042 c          771 g         1682 t
ORIGIN      
        1 tatcctccta gcaactattt aaatacccaa aaaaattacc tctagataat atcataccta
       61 cgttttcact tataaatttt ttcataaaaa aagcgtttag aggcataatc gttaatacag
      121 atggtaacca atgtatctgg tttgaactgg gatatcaccc tctccatata tgtattacta
      181 agactaatag atactataaa agacttgata gttttgcatt gattttgcct aatactgagc
      241 ataggtgtat gctaaacgat actataagga gtgtgtacat aatgaaaaga attctgttta
      301 tcagtttatc aaatttattg ttacttactg cttgtgggac ttctgcatca aagaacatac
      361 cttcagatac gcaaatttcg aatagtatcg attcaacaat ttctacaaat gagaaaaatt
      421 ctccggtaga aacttccgat ataaaagttt ctacctctgc aaaaaacagg gtaaagaaac
      481 tgtcagcacg tctcctttat ttcaaacaaa ctctgaatta gcttcttcat cttcttcagc
      541 aaataatgat gatagtttcg cgtttactcc taactaaatg caacctttac aaatgcttta
      601 cgataacaag cctgagctaa atgatcctga tatcagtttt gcattttttg aaatgattgg
      661 atcggatgat ctttttaaaa ctactagttt gtctatccga aaataggaca gttctggcag
      721 tataggtttt tatcgagttt ctccaccagg cctcgttaca gagacagatt ctctaggcga
      781 accttttgaa taaatcaaaa atcatgaaca atcactgcca actaaataaa gtgccttcaa
      841 aagcttggtc ttctcgcttt tgaaggcact ttatttaaat ctttatgaaa ctaaagtatg
      901 ttcatatttg ttgctatagt tatatagata ttctgttgtt tccaactcat aaacgtgagt
      961 atattttgcc actacttttc cgcatttttc taatatttca ttgcgatcga cgtcatgata
     1021 ttcgtctacg cagatcacaa cacaattttc taatttactg attacttctc caaccacttt
     1081 ttgtttcaag ccaataggtt ggcaaatata tttttttcct aaaatgatag tttcgttatt
     1141 catatttcat ccatccttaa tgtttttcca ttatttaaaa tgataatacc attaaaatat
     1201 gattatgaaa atcaataaca cttgtgattt tataaaaaaa taaaaaaacc gaaaaacaga
     1261 aatgcccact gtctttccgg ctctttttat tcttgatttc tcttcttttt tgtttcaata
     1321 gacgatttta gttattaata aatgaaaaag catttatatt aaaatttgct aataaaagat
     1381 ctacatattt ttctagaaat gcttgatcga tttcatcata ccctttcgtt actccgcaat
     1441 cgatatctaa aacaccgatt aaattacctt cttttaccat tggcactacg atttctgatt
     1501 gtgcggctga atcgcaggaa atgtaatttg catgggtttt gacatcatca acgatcaatg
     1561 tttcttgttt ttcagctgat tctccacaaa ctccttttcc catcttgata cgtgtgcaag
     1621 aaactcgccc ttggaacggt cctaaaatca attcattacc atcgaataaa taatatcctg
     1681 caaagacagt ctcaggcaaa gtctcattca acaatgcaga tgaatttgct aaatttgcta
     1741 accagttatc ttctgcttct aataatcctt gttgctgtaa taataaaatt tcgtatgcat
     1801 cttttttctg tttttctgtc cacatgataa aaaccgctcc tttttgatct atggagaaga
     1861 ttatagctca gtttttttgt aaacgctagg tttcctcctc aaaaaaacga gatacgtcag
     1921 gttaatcacc ttgaacgcat ctcgctgtct ttttctattc tgcttgttgg atttctgctg
     1981 ctaaatcagc ataatcaatc gtttcgtgaa caaaagtcgg atcatcaact ggaaaatgct
     2041 gtacaaggga cgagatgcgg ctaatctcaa cttttccttc agccacttca aaatccatta
     2101 catgtccgcc aaatgtatgt gtatcatcga taaaatgcaa gtgaaatccc gctgcagcaa
     2161 ctccttggaa taattcaggc gtaaagaacc cgactaatgt tccttggaca ttgctttgtt
     2221 ggaattctgg ttgagactct gaaatttttg ctagtcttct gtaaggtttt tcttgcttcg
     2281 gcatgatacg gatgtgcata tttttgaata atccagttat cttcactgcc aaaaataggt
     2341 tttccccggc ttctcttact aatatgtctt ttttcaattg ttctccatct gcagtttttg
     2401 agacagaaaa actagtatct ggcgtaaaat ctgtaattgc tgcatagggg gtaagttcac
     2461 ttccatctaa ttgggcaact gagccatctg atcttccttg ataagctacg ccatctaaaa
     2521 agatgacttc accatcaagc ccatgcaatg ttcccaatcc cagagttcct ttttctaata
     2581 tatgagcaat cgtttctgtt ccatccatca agccagccat caaagctcct aatgtcccgt
     2641 gctggtataa gattttttca gtcatgtcga cacttcctta atagaattga tctggtaaga
     2701 ttgtttctcc caatttctca ttatcacggt aatcaatcgg aatatcaata attacgggtc
     2761 cttctgtcgc aaatccttct tctaaagctt tttctaattc ctctacactt gtagctcgga
     2821 ttcctttagc gccaaaagct tctgcatatt tcacaaaatc aactggacca aagtctacac
     2881 ctgacgcccg ctgatatttc attttttctt ggaactctac catattgtag tgtccatcat
     2941 tccaaatcaa atgaacgata ttcaattttt tacgtaccgc cgtttctaaa tcctgggcag
     3001 agaataaaaa tcccccatcg ccggaaactg atacgatttg tgtatttgga cgcaccaatg
     3061 cagcagaaat cgcccatggc aatgcaacac caagcgtttg cataccatta ctgaataaca
     3121 aatgacgagg ttcataactt ctaaagtggc gtgccatcca aatataatga ctacctacat
     3181 ctacggtaac agtcatatca tctgttactt ttgactgaag cgtgttaata acttctaaag
     3241 gatgcaagat acctgcttct ccttttgatt gaacaatgtc ccgctccgtt aattctgctt
     3301 gaagagatgc taaatattct tttgcatctt ctgacacttg ttgaggctct aatgaacctg
     3361 tcaataaatc aagagtggct gagatatcac cgatcaattc tctttcaggc tgcataaaag
     3421 gatcgatttc agctggcgct tcatcgatca caatgatccg cgcatctttt tccgcattcc
     3481 agtttcttgc ttcatattcg attggatcat agccaatagc aataactaga tcacttcgtt
     3541 tcaaaagcat atctcctggt tggtttctaa ataaacccac acgaccaaag aaatgcgctt
     3601 ctaattcacg tgagatcact ccagctgctt ggaatgtctc tacaacaggc aatgctgtct
     3661 ttccaactaa ttgcctgatg gctaacgttt ctttttcact tgatcctcgc atacctacta
     3721 atagtaccgg tagttttgct tctctaatgc gttcagctag gtaacggata tcatctgcag
     3781 aagcagaacc taatttagga tcgctcaatg gcttgatgac attcccttgg acaggtgcat
     3841 ccactacatc ttgcgggata ctgataaagc tcgcgccttt ttttgaactc ttagccatac
     3901 gataagcatt ggcaatcact tctgaaattg tttctggatc ttggatttct gcactgtatt
     3961 ttgtgattgg ctggaacagt gctgcattat ccatgctttg atgggtcaac ttcaatagat
     4021 cgcttcgttt tacttgtccg gcaattgcta aaactgggtc accttctgct gtcgctgtta
     4081 ccaaacctgt agctaagtta ctagcaccag gaccacttgt tgcgataact actcctggct
     4141 ctcctgtaat acgtccgatt gcttgtgcca taaatgcagc attttgttcg tgacgagtca
     4201 cgattaattc aggaccttga tcctctaatt cattaaatac accatcgatt tttgcacctg
     4261 gtataccgaa tacataatca acatgatgat taatcaaact ttctactaca gatttcgaac
     4321 cttgtttcat tttttcgtcc attgaacatc gtccttttta tgctttattt ttaattatta
     4381 gttagaaata atcacaaata attgatacag tttctaaacc tgtttcattc aaaagtatag
     4441 cacgttttat ttcatttgtt tagccatatg tttcaaaaaa tgaaaaagaa tgacagtttt
     4501 tacataaaaa ctgtcattct taattgaaag tttcaattta taaagtctac agatccatag
     4561 ttctcatcaa tttacgattg ttgaagtaaa tcaaaccaaa tacgatagaa ggacctagta
     4621 gaatacacca ttggggcttt acgaaaaaga agagaaacaa acttgtcaat agtaaaaaat
     4681 ctagtaaact cacataccat tttttcaacg tatagtagaa cgctatccgt agaacttgat
     4741 ttggtttcga cgctggattt ctcacctgaa aataccagta gttgatgcta aaggaaactg
     4801 ataaacaagc aagtaaaaca aacaacggaa tcaaccattt tccataagaa aaacgtataa
     4861 aaaagaaaca atcaaaaatc attatcacac taactatcca agcaaatagc caataaaaaa
     4921 atccctttag ccaaaattgg cgaaacgtct ttatgaacaa acgtactggt gaaaaacttt
     4981 tttcttttgc taattcttct gtcataccta tcatcacgat gcaa
//
LOCUS       DBBGSP010000116         4947 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000116 DBBGSP010000000
VERSION     DBBGSP010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.117"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            45..380
                     /locus_tag="ACIZE9_003017"
     CDS             45..380
                     /locus_tag="ACIZE9_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094812.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
     gene            complement(637..2220)
                     /locus_tag="ACIZE9_003018"
     CDS             complement(637..2220)
                     /locus_tag="ACIZE9_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094813.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLSYGNEE
                     ADRDRESTFRLLNALIFDNKEFYLNILKKEIAKYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGNN
                     NEELQNHLNSLVDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKKLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            2342..2926
                     /locus_tag="ACIZE9_003019"
     CDS             2342..2926
                     /locus_tag="ACIZE9_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094814.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            2937..3182
                     /locus_tag="ACIZE9_003020"
     CDS             2937..3182
                     /locus_tag="ACIZE9_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094815.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            3188..3910
                     /locus_tag="ACIZE9_003021"
     CDS             3188..3910
                     /locus_tag="ACIZE9_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094816.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            4041..4784
                     /locus_tag="ACIZE9_003022"
     CDS             4041..4784
                     /locus_tag="ACIZE9_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094817.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
BASE COUNT         1805 a          663 c          818 g         1661 t
ORIGIN      
        1 caatttccta ggaaaaatag ttaacataaa aggaatgaat tgttatgaaa caatatttaa
       61 atgaatggaa agcgatagag gggtcattag taacgcaaag aataaaggaa ttacctgatt
      121 gcttagagaa ggatcatttg tttcaaatac gagaaatgtt gaaaaaagaa cagtttgatc
      181 cagaccaatt tttagtagtc gagtatccaa ctattggagt gtactgttgt aaccatatca
      241 atgatggaaa atattttatt attcaggagt atggaggaca gttaactcct ttctatacta
      301 catgggaaat gagtgaagaa ggaatcaata attttccatg tgaaagcatc gaagattcaa
      361 tttcacacac cgaatgttaa ttgattataa ctataaaaaa ggattgaaca ttatgttcaa
      421 tccttttttc aatgaaatgt tttccgccat ttcattgttt ggtgcgattt ctattttatt
      481 atatcaaaat aaagagagat tctaaagaaa gaagagggaa atatataaat caagcgacag
      541 tatatttatt attaaatgct attgtgagaa tataactaat tagtttaatt tgaaagtaaa
      601 tatacgctat aaaagtgcat cttgtgttat aaaaaattat tttattttgt gaacataatt
      661 taacaattct ttctcggaat tgatttcttt tcttaaatag tcttcagact tattaataat
      721 attatctatt atgtctagat acatatcact tttcgattca gctaattcat acagtttttt
      781 taattcttta tcctttaatt gaaaaccctg atccatagtc actgcatttg gatatagaag
      841 cccactataa tgtttacgta aattcacttg gaatttctga ttataaaagt ctaacagatt
      901 agaaataaaa ggcggaaaat tactgttttt gtaaaattga ttatttccat ttaggttgta
      961 tagtaatttg ttaaattgct cctgatttaa tttattgtaa atccatggta atacttccat
     1021 atccttatct gctaacctga atgaactagc atcggtaaga tgttcgatca taaaatctat
     1081 gaacatctct ttttcaccaa aatataaata ttgattatat attgtttcta atgttgaaga
     1141 tggtagcgaa gaaactctca ttttttgctg gagtatagga tcaactagac tatttaagtg
     1201 attttgtaat tcttcattgt tgtttcctag aactgcaagg gaacgtaaac ggtagtaata
     1261 ttctatttct gttagtactt gttgtttcgg tttaaaatca tttattgata tttgtaaatt
     1321 ttgaattgtc tcgtctgaaa aatcatgttg taattctgga tgggtagcta taaaagtaag
     1381 taaaaagaac ccttttgtat acgtgatctg ttgattttca ccaagtgatt tattaatttc
     1441 ctctcttgat tcagctgtga acctatactt tgcaatttct ttttttagaa tatttaaata
     1501 gaattcttta ttatcaaaaa ttagggcatt aagtagtctg aaagtacttt ccctatctct
     1561 atctgcttcc tcatttccat aagataattg aaaaacaaac ttaaaggctg tcttacatag
     1621 gttttctttg gctttttcgc ttagtttatt tagatagcta ttttttagtg cagagtgaaa
     1681 ttcttcaggt gtaacagaca tagcatgtat gcgacttgca tattgtataa tttcgatcgt
     1741 tacttttttt cctaatattg gattttttag gaatataatt tcataggact tccgtataac
     1801 atcctgacaa gtttcttttg ttatatctct taattcccaa gtattaccgt tgtaagtgac
     1861 tacaggatga gctgaataat ttctttgatc cttaatatat tttaaatcct catattcata
     1921 gctatcaatt agctcagttg aactataagc tttttctagt agttccattt cccattttgg
     1981 agagtttgga tcactttttc ttagtctagc tatatcttct aaaattttct tagaagtatt
     2041 atcctcgtaa atatttgcta aatcagataa tttatcaatt aaatctaaaa taagcgcact
     2101 gtaattgaca gctattgcag aacgataatt tccctgataa aaactacttc taacttcttc
     2161 taataatgga ataattctag gatttttaac tttttttatt tcatcatcta atataaacat
     2221 ataaatctcc tttttttatt tgtatgacaa gtttaccata aaaaaaaatt aaaaagcgag
     2281 acatatttat gttgttgtgt tatcataata acataaatat gtagagtgag atgatgaaaa
     2341 aatggatttg aaacaatcgt tttacatctg gttatatcct gataatccta tgtcaataat
     2401 ggctgatatt tttgtagtta gcatcttatt gtatttattt tatctaattt tctttcacaa
     2461 tttaatcggg tacatgattc ttgattggaa aggaatgttc gatatagaaa gaaaaccatt
     2521 tgctaacaat caaacctata ccgtcttcga aagtggagat tgggaagaaa atgaagttga
     2581 tgtgatccat gaaattggat tagctttatc aggaatacaa gatgctgatg ttttggtatc
     2641 aatgacaacg gatactggat acaacgctta tgaggtattt tatcttatgt attttatatg
     2701 gcgtgatggt caagaaatta tcaatggtcg tgctgaaaaa acaatcaatt ctaatactga
     2761 aatttctttt tgtatgggtg aaggggaaat gattgtatat aaagatgggt cagcaaacat
     2821 taaaacagcc tttggtgata ttgaaacaag tattaaggaa cttagggaat atgtgcagaa
     2881 cccatataat tttcaatatt tagcaggaag aataaattta gtttaggagt aaaaatatga
     2941 aaaaaattat aaatcaacca acaaatcact tgataattga aggtgttatt ttcgtaacaa
     3001 tgtattttac tgtaggaaat ggcatctcaa atacaatcat tcaaaaaaat ccacaatacc
     3061 tattatttag tctttatgct tggattgtac aaatggtttg ggtttccata ttgatgctgt
     3121 tgttttattg gatagtacgg gttattcttt tattgttaaa caaaagaaaa aaggataggt
     3181 gaataaaatg aaatcaacta aattgaaggt tgtattgtta tcgacagcag cattaataac
     3241 ccttacagca tgtggtacaa ctaatagtgc taataataac aaagacacaa agtctagtag
     3301 tacgatggtt actaaaaaca gcactacatc ggcatcaaca acaatgtctt caatgactga
     3361 aaataatgct gaaaagtatc aaaaatacga agacattaat aaaggtcaaa agccggatga
     3421 agtttataac aactttatta atacagtaaa aaatgatgaa aattatggga atgatccatt
     3481 gcaaaataaa aatctgacta tcgttcttta caaacctgat tgtccagatt gtcaaaaagc
     3541 agaatcaaaa atcatgcaag aaataaaaga aggatttagt tatgctccaa cattaatgca
     3601 tgatattacc ataaataaac cagcttacga gtattacgca gttgctgtag atattactga
     3661 tggtgtacct gagtgggtac aaaacattcc tggtctggct gatgagaaca atcaatatca
     3721 tacgccaaca gttgcagtag taacaccaaa gaaagttaac ggcacactat actgggatgt
     3781 aatgggaatg acaacaaata caactgatga aatgattgaa agtacaacta aatattatat
     3841 ggatttggga gcatataaat tatatcaaca atcagagcct gttatggacg atcaatccaa
     3901 agttaaatag atctttaggg cgtaagccct atttttttaa aattaagtga taacaaataa
     3961 atgatttctg aaacaaacgt tcttactcaa ctactcgaaa cacacaagct aattaactag
     4021 attataaagg agaatgcgta atgaaagaaa tcagtgcaaa tgaagctcat attccgcaaa
     4081 agaatcaggt tggtatatat aaggtgcttc atggtgaagg aatttataaa atacagttac
     4141 ttaccggtta caataatggt gcaaatggga agtggttaaa ggcaacaagt attcgtgaac
     4201 ttagaagtga agtagaaaaa attaggcttg gtctcacaag tgaagaaata gctaaactga
     4261 agggaaataa ttcttttgta attgaaaaag aaaaggaaaa acatctactt tatcgtgagc
     4321 tgaaaattga agaatactat gaaattgatt tacctgaaaa attaagaatt attgatcaac
     4381 gttcagaaga aaaatggaaa actgaaatat atccaagctt aaatgactac aagacatcag
     4441 gaaagcccat gtataactac acaggctttt taacctacac acaatacaaa tatgcctttc
     4501 gcaaattaaa aggcattaaa caagctgaaa ttgccctgta tgagatgaaa aaagtggata
     4561 gattgaaatt gattcaagat ttagtgcaaa atacatggaa tcaagcgatt gtcgagctag
     4621 aaaaagaaaa tgggaaaatt ttaactaata aatatctgat cgtaaatgaa attgaagaat
     4681 taattggttt attttcatgt gaaaaaggtg aagtcttctt gaagtcatca ccaacctatt
     4741 caattttgga cagtccgtat cagtttatac aggcaaggag atgagttaga tgtctagctt
     4801 gaaagatgac tatatccaag caaaacaaga gtatgaaaaa atacagatgt tgaaatctga
     4861 gaaagtcgaa ttatttttaa cacaaaaatt agcagaggat catattgcta acttagatgc
     4921 taaaacttta gaggaatatg atcggca
//
LOCUS       DBBGSP010000117         4942 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000117 DBBGSP010000000
VERSION     DBBGSP010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4942
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.118"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..889)
                     /gene="ligA"
                     /locus_tag="ACIZE9_003023"
     CDS             complement(<1..889)
                     /gene="ligA"
                     /locus_tag="ACIZE9_003023"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGC6094818.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSL"
     gene            complement(906..3140)
                     /gene="pcrA"
                     /locus_tag="ACIZE9_003024"
     CDS             complement(906..3140)
                     /gene="pcrA"
                     /locus_tag="ACIZE9_003024"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGC6094819.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            3295..4854
                     /locus_tag="ACIZE9_003025"
     CDS             3295..4854
                     /locus_tag="ACIZE9_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HGC6094820.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
BASE COUNT         1254 a         1034 c          959 g         1695 t
ORIGIN      
        1 gtagcgagaa ttcattcact ttgatgacga ttccatcgat ttcatagggc aaatccacac
       61 gtttgtcatg atattcttca atgtatgacc acacttcatc aatcgaatga catagacgtt
      121 tttcccgatt cgtgtggaat ccaatttttt ctagctcttc tagcgcatca tactgggttt
      181 ttgcttgcat aggaccgaaa tcagctactg tgtataaaaa agtgtccaga tttcttttcg
      241 ctgtgatttt agaatctaac tgacgcaaag aaccagctgc ggcgttccga ggattcgcaa
      301 agatatcttt tccctctgct tctctgtctt ggttcaattg gacaaatgac cgttttggca
      361 tgaaacattc gcctcttact tcgatgttca ttggttcttt taatttgatt gggaccgacc
      421 ggacagtttt taggttttca gtgatgtttt ctcctacagt tccatccccg cgagtcgcac
      481 ctctcacgaa atttccatct tcataacgca aagaaacgga aagtccatct atttttagtt
      541 cacagcaata gtcaactaca cgtcccactg ctttttgtac acgttgatca aaagctatca
      601 gctcttcttt gctgaaaacg tcgttcaaac tgtaaagcgg aatatcatga gtgacttttt
      661 caaaaccttc taatactttt ccgcctactc gttgagtggg agaatcagac gtgatcaaat
      721 caggatattg ttcctcgatt gctactaatt ctgcgtattc tttatcataa acatagtctt
      781 ccactgttgg tttatcttct acgtagtatt cgcgagacca ttggttcagt cttgtacgaa
      841 gttcttctgc tcgtttagca gcttcgtcaa tcgtcatttc atgttccatc atttaccctc
      901 cactactaag ctttttcaat tggcgcaaag gcagccaaaa gacgttttac tccttgactt
      961 gggaaagcca catctagttc tagatccttc gacgtcccgc ttactcggac gactgttcct
     1021 agaccccatt ttttgtgttt gactttatct ccaggtttcc agctgttatt ttcccctcca
     1081 gtagcacttt tagagggaac aaccgctgtc tctggctgtt tatagctata tgctgttttt
     1141 ttagcgaata caggcgtttt tttaggcgta ggacgcatgc cttcgatttc cagtaactcc
     1201 tgatcgattt cttctacaaa acgagaaggt cggttatatt gcgtccgtcc atataatgtt
     1261 ctggagaaag catttgttaa atacaacgct tcttctgctc gcgtgatccc cacatatgcg
     1321 agacggcgtt cttcctccag ttcgctttct tccatcaatg ctcgagataa aggaaaaacc
     1381 ccctcttcta gaccaatcag gaatacaact ggaaattcta atcctttggc tgcatgcaaa
     1441 gtcatcaatg tcacttggga agcatcttct tctaaattgt caatgtcgga aacaagtgcc
     1501 agatcattta agaagaccgt tagtttttct tctggtgcat cagcgtcttc ttcattttgc
     1561 tgttcgaatt gtttgtcgaa ttcttgtgtg accgttaaaa attcctccaa gttttcgatg
     1621 cgtgcttgtg cttctaatgt attttggatt tttaagtctt ctagatatcc gctacgatcc
     1681 aaaacctctt tcgtcaattc tgtcactgtc aagtatggga tcatctgagt gacttcttgg
     1741 atcatctctc caaatgcacc taattgctgt cctgcttttc caccgatatt tgccagatcc
     1801 acattttgcg ctgcttcaag cagtggccat tcatgaagag aagcaaaact gcgtagtttt
     1861 tcgatagatc ctggtccgat gcctcgtttg ggcgaattaa cgatacgctc aaaactgatt
     1921 gaatcttgag gatttaccag cacattcaaa tacgctaaaa tatctttgat ttctttacga
     1981 tcgtagaact tgtgccctcc aaccatttta taaggaatat ttgctttcaa cagagtttct
     2041 tccattacac gagattgtgc gttcgtccgg tacaagatgg caaagtcgcc gtaattccga
     2101 tgattgcttc gaatctcttc ttgcatccgg tctacgataa aacgggtttc gtctcgttca
     2161 ttatctgcac ggtagtaagt gatcttgttt ccttctttgt tttctgtcca caagtttttt
     2221 ggttttcgat tgctattgtt ttcaatgact tggtttgctg cgctaaggat gtttttcgtg
     2281 gagcgatagt tttgttctag caaaattact gcagcatctg gataatcttt ttcaaaatcc
     2341 aagatgttct gcatatctgc accgcgccag ccgtaaatac tttgatctgc atctcccacg
     2401 acgcacaggt tcctaaatct acctgccaat aaattgacta gcgtatactg tgcgtgattt
     2461 gtatcttggt actcatctac atgaatataa tggaatttgt tttgataata cgtgagtgaa
     2521 tcaggatgtt cttcaaataa tcgaatcgta ttcatgatca ggtcgtcaaa gtccatacat
     2581 tgattatatt gaagctcttt ttggtaagca gcataacatt ttgccgcaat ctcttcgtaa
     2641 taactgcctt gcatttttgc aaaatcctga ggggtctgca ggctgttttt tgcttgagag
     2701 attgttccta atatacttcg aggatcatat tttttcggat caatgttcag ttcttttagt
     2761 atccgtttca tcaaggtcag ctgttcagaa gaatcgatga ttgtaaagtt ccggttatac
     2821 ccgataaaat caacatctct tcttaaaata cgcacacaca tcgagtgaaa agtcgatacc
     2881 cagacatctt cgcctccaga tgcgagaatc gcattgacac gttctttcat ttcttttgca
     2941 gccttattgg taaaagtaat cgctaggatg ttccaaggat tgacttcttt ttcctcaatc
     3001 aaataggcaa tgcggtgtgt cagcactctc gtctttccac ttcctgcacc tgccattagc
     3061 agtaatggtc cgtcagtgtg aagaacagct tctttctgac gggggttcat cccgtttaat
     3121 aattcagctt tggatgacat taacaacatc ctttctttta tcaatcttgt taattatagc
     3181 attttcttgg ctttcattaa actagctagt tcaaaatcat ttgtttcttt ttatggattt
     3241 ttccttgtca attcgttgat ttcgcgctaa attaaaagaa agcgaggcgt ttgaatggaa
     3301 aaaaaaggaa aaatcaagaa attagataag actcagatat attttattct aaaaggaata
     3361 tttgttggac tgctgacagg aatcgtcgtt agcctgtttc gattatctat cgaaaagcta
     3421 agcgatttag ttcgaagtat ctatgaaatg agtcgggaac agccgattta cttaattggc
     3481 ctagctattt gctgcatcct tgcagcattt ttcgtgggtt atctggtcaa aaatgaaccg
     3541 gatatcaagg gaagcgggat tccacaagta gagggacagc ttcgcgggga attatcaatg
     3601 aactggttct ctgttttatg gaaaaagttc attggcggtg tactttcagt tggtgcgggc
     3661 ctttttctag gtagagaagg accttctata cagcttggcg catccattgg acaaggagct
     3721 ggacaattgt ttcggagtcc atcttcagaa gaaaagattt taatttctag cggtgcaagt
     3781 agcggacttg cagcagcatt caatgctcct atcgcaggat tactctttgt tttagaagaa
     3841 atccatcact ccttttctcc acttgtttgg ctgacatcat ttgcttcagc aatcactgct
     3901 aacttcgtct ctctttactt tttcggcttg agacctgttt tatatctagg tgaccttcct
     3961 tctttgccgt tgaaatatta tggttcctta gtgatcttag gagtacttct aggcatctta
     4021 ggttttattt atcagaatgt cttgctggct ttgccaaaat tttacaaccg attgccttta
     4081 ccagcttatt ttcacgggtt cgttcctttc ttgctgattt tgccaattgg ttatttatgg
     4141 cctagtactc taggcggagg caatcaaatc gttttagctt ttggacatgc ttccttgcca
     4201 atcattatga ttatcggttt gtttgttctt cgattcgttt tttccatgat ttcttacggt
     4261 gggggtcttc caggggggat tttccttccg atattgacat tgggggcttt aatcggtagc
     4321 ttttatggaa acattatggt tgatttcggg atggatccaa tctacatcaa ggattttgtc
     4381 gttattgcca tggctggtta tttcacagcg attggaaaag caccgctgac agcaattatt
     4441 ttagtgacag aaatggttgg ctctcttaat catctgatgc ctttaggatt ggctgctctt
     4501 gttgcttata tcgtcaatga ccttctcggc ggtaatccaa tttacgaatc attattggaa
     4561 cgtctacttg gaaatactca gaccgcctca ctaaaaggtg caaggacaac ttttgatttt
     4621 ccagtaacgg cagagagttc tttagacgga ttaatggtac gagacttcaa ttggcctaaa
     4681 aatatgctgc taatctctat acgcagagga aatcaggaaa tcttgactca cggtgatacg
     4741 atcatgaatg taggagatat tttggttatc ttgactgatg aagcaaactt gccaagaatc
     4801 aagcaggaaa tcgaggctaa atcttctatc acaaatttga agcaatcatt ttaacgaaca
     4861 tggaaaaact attttacaac aactattcat ctacactact tgattctata tgattctata
     4921 aaaaaagaag aggctgggaa aa
//
LOCUS       DBBGSP010000118         4926 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000118 DBBGSP010000000
VERSION     DBBGSP010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.119"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..832)
                     /locus_tag="ACIZE9_003026"
     CDS             complement(<1..832)
                     /locus_tag="ACIZE9_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGC6094821.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            complement(846..1643)
                     /locus_tag="ACIZE9_003027"
     CDS             complement(846..1643)
                     /locus_tag="ACIZE9_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HGC6094822.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            complement(1676..1960)
                     /locus_tag="ACIZE9_003028"
     CDS             complement(1676..1960)
                     /locus_tag="ACIZE9_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HGC6094823.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            complement(1957..2958)
                     /locus_tag="ACIZE9_003029"
     CDS             complement(1957..2958)
                     /locus_tag="ACIZE9_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HGC6094824.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            complement(2960..3862)
                     /gene="gnd"
                     /locus_tag="ACIZE9_003030"
     CDS             complement(2960..3862)
                     /gene="gnd"
                     /locus_tag="ACIZE9_003030"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HGC6094825.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            4026..4874
                     /locus_tag="ACIZE9_003031"
     CDS             4026..4874
                     /locus_tag="ACIZE9_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC6094826.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
BASE COUNT         1487 a         1079 c          796 g         1564 t
ORIGIN      
        1 aaaatccgtc atcatagtca tcttcgtcat caaaagatgc tgaattgtta ttgcttgtgg
       61 caggctgtac ttgtttccct ttttgcgact ggacaaagat caaagcgata ataatcccaa
      121 aaatggcata agtaaccatc gtaatatcta aagatttcaa aacaacactc ataaaataag
      181 caaggaagaa aaagaccaga taatcttttc gaccgataac gtatacagtt gtcgcgatac
      241 cgattgccgc taaccctcca cctactactt caagaatgtg gataacgact gttccctcta
      301 aagctttgat tacatcagcg atcaatggcg cccctaaata taaagcaatg aaaacaagcg
      361 gaacgaataa taaaaatgag gcaaccgttg gataaagaat aattgatcgg gccatagctt
      421 ttgtattcaa atcttctaca gctttgtctg tatatttacc taaaaaagta ttgatgaaaa
      481 aacgaaactg atacaagtaa cttccgagca atccgactgg caccgcaacg gcaatcgctg
      541 cttctggcga cagatcccct aataatgcga ctggtactgc gatagctgct gcaatagatg
      601 gttcagctgg cattgatcct cctggagaaa aaacccccat ataaatcatt tgcaaagcgg
      661 ctgtaacaat catcgcttgt gcaacttccc ccatgatcaa cccgacgact aatccagtca
      721 tcaaaggaga aaaacgtaag gtcaacgtgg ctcctccacc taaccagcgg gacataaccg
      781 cggctaccca taaagcaatc aacaaacttt gtactacact taatgtttcc atgtgtcctc
      841 ctccttcaga tctttctgat ataaccttcc agttccatca ttgactgtat cagtgatttc
      901 tgtgttacct ctataggaat caaatgcact ttctctttcg aatcaataaa ttcagccatt
      961 ttatctatta tctgtttatc tttcggaaat aatcccattt gttctagaga aaccggcagt
     1021 tctaattccc gatacaaagg atataactcg tctatttttt cccagcgacc ttctagtgcc
     1081 agttgataga aaatcccata cgctactttt tctccatgta gaaaacgatg gctttccgga
     1141 atatatttac tgatagcgtc atgcatagca tgtgctgccg catttcttgc gtatttatct
     1201 cctaatcctc caactaaacc agcaacagca aagataatct ctgaaagctg tttgaactcc
     1261 gatgtcagtt ttctttgtgc catatcttgg attgctttag cagaatgatt caaaatctct
     1321 tctttgcaga tcttcgcagt atcttgtgct agcttcaaaa atgattcatc ttgcaaaaaa
     1381 tcttgttcta agatgagctc agattcatac cattttgcta gtgtatctgc taacccggca
     1441 atgaaatatg gaacagggga atcaatcact aattggggat ctgttataaa aaaagcagct
     1501 tgtctgtaaa agtgttctgt tttcccttct gcttgtccat tctccttata catgacagca
     1561 agaggtgtcc atggagcaca attactagct aaagtaggga tgactccgaa atcgattctt
     1621 gcaagattgg cactataacc cactagatcg gtcagttttc ctccgccaac gccaactacg
     1681 aaatcgattt catttttttg atgattgtag ctattcgtct ggcttcagca taactacatt
     1741 ctccagaata acgatgataa aaaaattgaa tcgtttcgtc attcaaaaat actaatttag
     1801 gtagcgcctt ttcccatgat accgttccgt gggtgaccag tactcttttc gcgccgtatg
     1861 atttcaagag atcagaaact tttgaaatac caccttcttc atataaataa aattgagggc
     1921 ctgttttcac ttttaaaccg ttcaccattt tcttcatcat ccttttatat agttgctctt
     1981 tgtctggaca gaacgttcag gaagaaggtg ctgactgatc tgttcgacat ctctgacaca
     2041 tttttcaccc attgcttcta aacattccct tgtgtaggcc gatatatgtg gcgtaatcac
     2101 tacttgttca aacgctaaat acggatgatc ttgacgtccc ggttcttctt ctaaaacatc
     2161 tgtggcatat cctgcgatct ttccgctttt cagaccatta atcatcgctt cttcatcaac
     2221 tagagcgcct cttgcactat tagatagata aacattttct ttcatctgat cgacttcttt
     2281 atcagaaatc atgtgatagt tctcttctgt caaattcgca cataaacaaa tgatatctga
     2341 ttgttccagt aattcttgaa gttctacttt ttttgcacca aagctttcga tgtataaatc
     2401 tgatttgtaa ggatcataag ctagaacatc acagcgaaaa ccgttacgca aaatttcgat
     2461 tactccgctt ccggtatttc ctgcaccaat cacaccaact gttttgttaa acagcgtcct
     2521 accgacgaac tccgcccgat cttcccatcg atcgtccttg actcttgctt gtgcttgtgt
     2581 cgtgcgtcga agcatggaca acaaattagt tatattattt tctgctacag catttcgttc
     2641 aattaaagca ggtatgatag atacgattgt ctggtgttct tttgctgctt ttaaatcaat
     2701 attgttgtaa ccaataccat gtcgggaaat caatagcagt tcatctttgt tttcaaaaaa
     2761 atctcgtcga aaaaatggcg taacacttgc aataatgata ttgaatcctt taagtaactc
     2821 cgctagttct tttcctggaa tctcttgatc aacagtaaag aaatgaacgt ctccaactga
     2881 ctttaatctt tccaagtggt gtggaaagac tcttccgaaa ctgctggaat taacgattgc
     2941 tatatgataa tctggcattt tactcaccct tttcaactat ttcatgtccg ccaaacccat
     3001 ttcttagtgc tgaaactact tttgctgaaa aactatcttc ttcctgtgaa agattcctca
     3061 tgaacaaact agttgcaatt actggaactg gaacagccat ttctagcgct gtttcaaccg
     3121 tccattttgc ttcacctgat gcagaaacga ttccccgata attacttaaa ttgggatgtt
     3181 cgtttaactg atcttccatg atttccatca gccagccgcg aatcaccgaa ccatgattcc
     3241 aaacacgtgc gacttgttcc aagtcaaaag catactcact tttttgtaca agttggaatc
     3301 cttcaccgat tgcttgcatc attccatatt cgattccatt atggatcatt ttcaagaagt
     3361 gtccgcttcc ggatgcacca gcatacagat atcctctttc aattgctaca tctttgaata
     3421 attgttccac ggatagaaaa gtttctttat ctcctccaat cattaagcag gcttgatgtc
     3481 gtgctccttc gattcctcca gaagtcccac aatccaagta accgatttca tttttctgaa
     3541 actcttctgc tcgacggatt gaatctttat aataagagtt tccgccttca ataataatgt
     3601 ctcctggtcc gagttttgga aaaagttttc ttaacatgtt ttcggttatc tctccagcag
     3661 gaagcattaa ccagatgatt tttttctgct caaaagtagc tagaaattca gagatctctt
     3721 gataagcagg aatgtcattt tctcttgcct gactaacagc tgtacttgaa atgtcgagtc
     3781 cttgtacttt gtgatggtgc tcttttaagt ttaaagctaa attcaatccc atttttccca
     3841 aaccaattac accaatttcc atgatagcgc ctccatttct tataccctca ttatacaaaa
     3901 aaattttttt gtaaatagat tttacaaaaa tattttttgt ttgatttttt cctactctcc
     3961 ttgtatcttt aacattaatg agaacggaaa aaatgataat cttattatga aaatgaggaa
     4021 ttctcatgag cgtctccata agactacaaa tcaaaacaat gtacaacgac ttcagcccaa
     4081 aagaacaggc tatcgccgat tatattttag aaaatccaag caaagtaagt catagtccta
     4141 ttagcaattt agcaagtgaa ctgggcattg ctgactctac tttttttcaa tttacaaaaa
     4201 aacttggtta taatggattt aaagatttta aaatggccat gttgatccaa gaaaatgatc
     4261 tatctgctat ttctatccac gaaaatattc agaaaacaga tactgagctc actatggcgc
     4321 aaaaggtgtt cgagtctagt atttcaactt taaatgacac aaaaaagttg ttacaacaaa
     4381 aggatctaaa aaaagcggct actattatca atgaatctaa acgtgtctat tttttcggtg
     4441 ttggcggttc agagattgta gcaactgacg cttatcataa atttttgcgt tcccctatcg
     4501 caacttctca cagcacggat taccatattc aattgatgga agcttcttta ttgacggaaa
     4561 aagactgtgc tgttttgatt tctcacacag ggcaatcaaa agaaacaatc catattgctg
     4621 aaaccgtaag aaaaactgga gcaaaaacaa tcgttattac tagccaagct aattcttccc
     4681 ttgctaaact tggcgatgtc gtttttattt ctatttctga agaaacagaa ttccgatctg
     4741 aagctttagc ttcccgtatt tctcaactaa gcattttgga ctctctatat gtgattttga
     4801 tgttttacaa cgaaaaagaa tcacgtcgtt ctatcgctaa agttcgacat actatttctg
     4861 aaatcaaaga atagcaccat aacagaaaaa gcgaaaaatc cataaaacaa aaaaagccac
     4921 taccaa
//
LOCUS       DBBGSP010000119         4924 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000119 DBBGSP010000000
VERSION     DBBGSP010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.120"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            83..970
                     /locus_tag="ACIZE9_003032"
     CDS             83..970
                     /locus_tag="ACIZE9_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC6094827.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="ACIZE9_003033"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="ACIZE9_003033"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGC6094828.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="ACIZE9_003034"
     CDS             2272..2718
                     /locus_tag="ACIZE9_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HGC6094829.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="ACIZE9_003035"
     CDS             2991..4343
                     /locus_tag="ACIZE9_003035"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HGC6094830.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="ACIZE9_003036"
     CDS             4514..4801
                     /locus_tag="ACIZE9_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HGC6094831.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1693 a          813 c         1030 g         1388 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaac cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 cccc
//
LOCUS       DBBGSP010000120         4719 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000120 DBBGSP010000000
VERSION     DBBGSP010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.121"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..1097)
                     /locus_tag="ACIZE9_003037"
     CDS             complement(<1..1097)
                     /locus_tag="ACIZE9_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HGC6094832.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENA"
     gene            complement(1227..2603)
                     /locus_tag="ACIZE9_003038"
     CDS             complement(1227..2603)
                     /locus_tag="ACIZE9_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6094833.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2603..3259)
                     /locus_tag="ACIZE9_003039"
     CDS             complement(2603..3259)
                     /locus_tag="ACIZE9_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC6094834.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(3269..4546)
                     /locus_tag="ACIZE9_003040"
     CDS             complement(3269..4546)
                     /locus_tag="ACIZE9_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC6094835.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(4565..>4719)
                     /locus_tag="ACIZE9_003041"
     CDS             complement(4565..>4719)
                     /locus_tag="ACIZE9_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HGC6094836.1"
                     /translation="KDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDAI
                     SYGVRK"
BASE COUNT         1477 a          856 c          567 g         1819 t
ORIGIN      
        1 gcattctcat tagagaacac tccctttttt gtgacttttc tgaagctaga gtgaatactt
       61 tcaactgcat tagtagtgta catgattttt ctaatggcgc tgccataatc aaagagttgt
      121 tcaacatgag aaaagtttcg tttgcataca tctactgcac cagaataatg agaccaccga
      181 ttttgaaaac tgtcgaaggc agcgtgtgca gcgtttaaag aagaagcact gtagaatttt
      241 ttcatgtctc gacagacttc cttataatcc ttacttggga ggtatcgtaa cgcatttcga
      301 acaagatgaa caatacagcg ctgcacaatg acagaaggaa aaattgcttt tgcgccttct
      361 ttgagaccgg aaacaccgtc catcgaaatg aaaaaaacat cttctacacc acgtactttc
      421 agttcatcaa atacttgcat ccagcgattt ttagattctg tttgattgag ccataggcct
      481 aaaatctcct tgtttccttt aagatcatag ccaagaatgg tgtacacagc atattcttta
      541 gcttcatagt tttcgcgtaa agtgacgtac atacaatcaa cgaatagaaa tgcataacac
      601 ttggctaatg gccgagcttg ccattcttcc aattcaggaa ggacggcatc cgtgatatca
      661 gaaatcattt cgtgggaaat atcaaagccg taaatatctt caacggttgc ggcgatatcg
      721 cattgactca ttcctcgtgc atacatggaa agaaccttac cttcgatgtc ggagacatct
      781 cgttttctat taggaatcaa ctcaggttca aaagaagcct cccggtctct gggaacatca
      841 atgtttactt taccaaagct cgttttaagc gtcttattgc cataaccgtt tcgtcgattg
      901 tcatgtttct ttggctcttt agaatgggcg tcatacccta aatggttatt caattctcct
      961 tgaagcattt tttcaaataa gggaccaaac acatctttta aaacatcttg catatcctct
     1021 acagattcgg gttgataagt attcaaaatg gattcagcta acttctcagc atcaggattt
     1081 cttttctttc tagccatcgt gtaatcacct cttgatctta ttttagaaaa ataaaaaccg
     1141 tgaagcaacc acccgcctag gattgatggt tacttacacg gtttatatta cactctcatt
     1201 tttggtgcta aaaagcaccg aaaattttaa ttattgtcaa ttaataattc ttttggattc
     1261 cttcttaata tattgaatga agaaataatc aatgatacaa gaagtactaa actcataaat
     1321 ataactacat aaatcatgaa tttaggtaat acattgatat ctaaacttga taatgtcttg
     1381 ttaaatcctt cagcttctgc cccaccacct aattggctag atgcagattg tttagctatt
     1441 tgtttagcta tatcaccagt aaccttattc aatatattat tcccaagctt gtcagctgta
     1501 tattgagcta agaaatagga accaacgaat gcggggattg atataaatac catctcaatt
     1561 aggaattgac caaaaatttc taattttgat atacctaatg atagtaatac tgctatttct
     1621 ttctttctag cattcatcca taagaataat aataatgaaa ctacaactcc tgcaaatatt
     1681 aatgagccaa aaaataattt atttgaaatt gagtaaatac ctgatataga ttgttgtaat
     1741 gcagggtaat ttgatgaact tttaatcaaa ttatattctc tccaatttat atctaatttc
     1801 ccaagatctt ttattacact atcaagattc ttatcacctt ttacaaagaa tgttgcatct
     1861 tggtatacag ctgtatcttc ggtattacca taaactttag cagctgtatg aatatcagtg
     1921 attaatgtat tttcgtatag ttcttgtgct gcacttactc caccgctatt atgcccatcg
     1981 aatagacctt taatttctac ttctactgtt tcatctgcac ctttctcatt atcagcatca
     2041 aataaattag attttatttt tatcttatct ccaactttaa ggttattttt ttcagctaaa
     2101 tctttatgca ttaagatttt atttttatct tcattttcta aatgctttcc ttctactaat
     2161 ttatatgctt ctgatacaaa ttttgtttct tttgttgagt cgttaacccc agttaacata
     2221 actgttcttt taaaattctt tgctctttca ggtgattgat tcgcaagagt ctcttgagtt
     2281 tcaataatat cataatcaac taaatctgca acactgttta ttctttttac ataggagtct
     2341 atactatctg tttgagatat ctttttaata tcttcacctt ttacatttcc cccacctcta
     2401 ggtgttcctg gatttacttg tctatttatc tccatagaaa aactatttgt tatattagca
     2461 aatgtttctt ttgaagctct gtccgtagca tctttaatag ataaactaat gagacttaaa
     2521 gttgacatag ataaaataac taatatgata attaatgatt ttaaactttt tctagttaca
     2581 taagcaaatg cattttttat cattattcaa cctccaaatt cattttattt acttttttca
     2641 actttttacc acttagttct aaaatgatat ccgcagaatc tgctacttcc ttactatgtg
     2701 ttacaactat tacacattta tttctatctt tagctaatgt ctttaatata ttaattattt
     2761 ctccagcagt aacactgtct agattaccag taggctcatc agctagtatt attggagcat
     2821 ctgataccaa tgctctagca atagctactc tttgttgctg tccaccagat aatttcataa
     2881 catttctttt tatttgtttt ttatctaaac ctagttcaaa caagatactt tcatctgctg
     2941 atttatttac taatctaata ttttcaattg gtgataaata atctattaaa ttatagtttt
     3001 gaaatactaa agatatatta ttttttctat gattactata tcctttattt tgtatatctt
     3061 cattcttaaa caatattttt cctgtttgag gtttatcaag tccagcaagt aaggaaagaa
     3121 gtgtagattt tcctgttcct gactttccta ctatcgcata aaacttccca agttcaaatt
     3181 tttgatttac tcctgacaaa actttttctt tagaatttgc ataactatat gctacattct
     3241 ttatttctaa tatatccatt attttctcct aacttatttt tgataagatt tctttaggct
     3301 tcttgattaa cattaatgaa gaagcaaata caactgataa aacaataata cttattaata
     3361 ttaaataact ttgtccaagt gttgttatat ttgacataaa actactatta tttattaaac
     3421 ttccaccgga aatcattgaa tcctctgagt taatgaatcc atctacaatt acttttagta
     3481 atacatttcc taaaaataag gaagatatta tacttggtat cgatatgaat attaactcga
     3541 atataaattg cattataatt tgtatcttag atgttccaat agataagaat atacctattt
     3601 cataaattct ttcccttaac catagaatca agattaatga aagaacaacc atcccaccta
     3661 acataataga ataagtcatt acttttatta tatattttat tccactcact gactctaaag
     3721 actcttcaaa cgcattagaa tctttttcaa caaaatactt tgactcatca attttaagct
     3781 ctttcaattt gtttaaggct aagtctgtag attctgcact accagaatac attaaaattt
     3841 tatttgcaat ttcattattt tctgaattat ttaatatctc ttggcttgtt gaataatcta
     3901 caaacaccat attttcacta aaatcagaag ataatcctgt atatgtttcc tgttttttac
     3961 cagaaaagat ccctataatt ttaaatttat gactttttat ttttccactt ttttcaatat
     4021 ctagtaattc aagatcaact tcatcaccta attttagatt gttttgttta gcaaattctt
     4081 catgaacaat aattgaattc ttatcatttt cttctatatt tttaccttct ttaattgtaa
     4141 atactccact actaaataaa atatttcttt tagtattatt tgtagcttcg agtgaaacaa
     4201 cattcttaaa ttcgtcagat aaatcttctc tatttattct ttgttctccg ctaactactt
     4261 tagcatcttt tagttttgct aatccatcat attgaattat tttttcttca atttctttta
     4321 atttttcaat atctttaaat tgattaacat taaaatattt accatctttt tttgttattg
     4381 atattgaaga attagaactt tcatataaag ccttttctat ttcattgctt gatttcatta
     4441 ttgttaaaca agaatacaag caagaaagaa ctatagttaa tatgataaaa attattaaag
     4501 ttctattttt ctttcttgta atatatgcta tagcattttt tatcactttc ctaactactc
     4561 ctctctattt tcttactcca taactaattg catccactgg acaagcattt ttacatcgtc
     4621 cacatctgat acactccaga tgattgcaat tctcaactga atctttattc atttggcaaa
     4681 cttttttaca ttttccacaa ttaatacact tatccttat
//
LOCUS       DBBGSP010000121         4593 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000121 DBBGSP010000000
VERSION     DBBGSP010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.122"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            153..959
                     /locus_tag="ACIZE9_003042"
     CDS             153..959
                     /locus_tag="ACIZE9_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HGC6094837.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            977..1657
                     /locus_tag="ACIZE9_003043"
     CDS             977..1657
                     /locus_tag="ACIZE9_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HGC6094838.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGETF
                     SFWWLVRHADKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGH
                     EVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVFADKEP
                     QALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPES
                     VDIQEENQ"
     gene            1654..2625
                     /locus_tag="ACIZE9_003044"
     CDS             1654..2625
                     /locus_tag="ACIZE9_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HGC6094839.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2618..3646
                     /gene="vanB"
                     /locus_tag="ACIZE9_003045"
     CDS             2618..3646
                     /gene="vanB"
                     /locus_tag="ACIZE9_003045"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HGC6094840.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3652..4260
                     /locus_tag="ACIZE9_003046"
     CDS             3652..4260
                     /locus_tag="ACIZE9_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HGC6094841.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(4326..4499)
                     /locus_tag="ACIZE9_003047"
     CDS             complement(4326..4499)
                     /locus_tag="ACIZE9_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094842.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         1282 a          971 c         1232 g         1108 t
ORIGIN      
        1 attttgaccg acaggtataa ccctgccggt ctttttttgc tgctacagga aaactacaga
       61 ctggctacag ggaaagtaca gatgcgcttg ccataataac aatcgtacca gccacaaatc
      121 gtagttttat tgcaaaggag gcattcgatc aaatggaaaa aagcaactat cattccaatg
      181 cggatcatca caaacggcat atgaaacaat ccgtggaaaa gcgggctttt ctatgtgcgt
      241 tcattatttc gttcacagtc tgcacgctgt ttttggggtg gagactggct tccgtattgg
      301 aggcaacaca gataccgccc atccctgcaa ctcatacagg cagcagcact gacgtagtgg
      361 agaatttgga ggaaaacgct cttgccaccg ccaaagaaca gggagatgaa caggaatgga
      421 gcctgatttt agtgaacagg cagaacccca tccccgcaca gtacgatgtg gagcttgagc
      481 aactatcaaa tggtgagcgg atagatattc ggatttctcc ctatcttcaa gatttgtttg
      541 atgccgcaag aactgatgga gtttacccga ttgtcgcatc cggataccga acaacagaaa
      601 aacagcaaga aattatggat gaaaaaattg ccgaatataa ggcgaaaggc tacacctctg
      661 cacaggctaa agcggaagca gaaacttggg tggccgtgcc gggaacgagc gagcatcagc
      721 ttggtcttgc tgtggatatc aatgcggacg gaattcattc aacaggcaac gaggtttata
      781 gatggctgga tgaaaacagc tatcgttttg gttttattcg tcgctaccca ccagacaaga
      841 cagagataac cggtgtgagc aacgagccgt ggcattaccg atatgttggc atcgaagctg
      901 ccacagagat gtacaaccaa ggggtttgcc ttgaggaata tttaaaacca gaaaaatgag
      961 aaaaggatgt tatgttatgg acagaaaaag attgacacag cgtttcccgt tcctgcttcc
     1021 aatgagacgg gcgcagagaa aaatgtgctt ttatgcggga atgagatttg acggctgtcg
     1081 ctatgcgcag acgatagggg aaaccttttc tttctggtgg ctggtacgcc atgcggacaa
     1141 agataccccc tataaagacg gccttacggt gaccaatggt aaactcacca ccatgtcggg
     1201 cggcggtatg tgccagatga gcaatttact attttggatg ttcctgcata cgccattgac
     1261 aattatccag cgcagaggtc acgaagtaaa ggagtttcca gagccaaaca gtgacgagat
     1321 taaaggggtg gatgcaacca tttcagaggg ctggattgat ttaaaagtgc gaaacgatac
     1381 cgactgcacc taccaaatat gggtgacctt agatgatgag aaaatcatcg gtcaggtgtt
     1441 cgccgacaaa gagccccaag cattatacaa aattacaaat ggcagtatcc agtatgtccg
     1501 tgaaagtggc gggatttatg aatatgccca ggttaaacgg atgcaagttg ccttaggtac
     1561 cggggaaata atagattgca agctgcttta tacaaacaaa tgcaaaatct gttatcccct
     1621 cccggaaagt gtggatattc aggaggagaa ccaatgagaa aaagtgtggg cattactgtt
     1681 tttggatgcg aacaggatga ggcaaatgct ttccgcgctt tatcgccgga ttttcatatt
     1741 atccctacgc tgattagcga tgcgatatcg gcagacaacg caaaattggc cgctggcaat
     1801 caatgcgtta gcgtaagcca taagtccgag gtttccgagg cgacaattct tgcgctgaga
     1861 aaggtcgggg taaaatacat ttctacccgc agcatcggct gcgatcacat tgatacgact
     1921 gccgccgaga gaatgggaat ctcggttggc acggttgcgt attcgccgga cagcgttgcg
     1981 gattatgctt tgatgctgat gctgatggcc atacggggtg caaaacccac catgcacgcc
     2041 gtggcgcaac aagatttcag attggatcgt atccggggga aagaactggg ggatatgact
     2101 gtgggagtta ttggaaccgg ccatatcggg caagcggtcg tcaaaaggct gcggggattt
     2161 ggatgccatg tgctggccta tgataacagc cgaaaaatgg atgcagatta tgtccagctt
     2221 gatgagcttc taaaaaacag cgatattgtt acgctccatg tgccgctttg tgcggatacc
     2281 cgccatctga tcggtcagaa gcaaattgga gagatgaagc aaggcgcatt tttaatcaac
     2341 accgggcgcg gagcgcttgt cgataccggg gcgctggtgg aggcgttgga aagcggaaag
     2401 ctgggtggtg cggcactgga tgtgttggag ggcgaggatc agtttgttta taccgattgc
     2461 tcgcagaaag tgcttgacca tccctttttg tcgcagcttt taaggatgcc gaatgtgatc
     2521 atcacacccc atacggcgta ctacactgag cgtgtgctgc aggatactac agaaaaaaca
     2581 atcaggaatt gtctcaattt tgaaaggagt ttacagcatg aatagaataa aagtcgcaat
     2641 catcttcggc ggttgctcgg aggaacatga tgtgtcggta aaagccgcaa tagaaattgc
     2701 tgcgaacatt gatacggaaa aattcgatcc gcactacatc ggaattacaa aaaacggtgt
     2761 atggaagcta tgcaagaagc catgtacgga atgggaagcc gacagtctcc ccgccatact
     2821 ctccccggat aggaaaacgc atgggctgct tgtcatgaaa gaaagcgaat acgaaacacg
     2881 gcgtattgat gtggctttcc cggttttgca tggcaaatgc ggggaggatg gtgcgataca
     2941 ggggctgttt gtattgtctg gtatccccta tgtgggctgt gatattcaaa gctccgcagc
     3001 ttgcatggac aaatcactgg cctacattct tacaaaaaat gcgggcatcg ccgttcccga
     3061 atttcaaatg attgataaag gtgacaagcc ggaggcgggt gcgcttacct accctgtctt
     3121 tgtgaagccg gcacggtcag gttcgtcctt tggcgtaacc aaagtaaacg gtacggaaga
     3181 acttaacgct gcgatagaag cggcaggaca atatgatgga aaaatcttaa ttgagcaagc
     3241 gatttcgggc tgtgaggtcg ggtgtgcggt catggggaac gaggatgatt tgattgtcgg
     3301 cgaagtggat caaatccggc tgagccacgg tatcttccgc atccatcagg aaaacgagcc
     3361 ggaaaaaggc tcagaaaatg cgatgattac agttcccgca gacattccgg tcgaggaacg
     3421 aaatcgggtg caggaaacgg caaagaaagt atatcgggtg cttggatgca gagggcttgc
     3481 ccgtgttgat ctttttttgc aggaggatgg cggcatcgtt ctaaatgagg tcaataccct
     3541 gcccggtttt acatcgtaca gccgctaccc acgtatgatg gccgccgcag gaatcacgct
     3601 tcctgcactg attgacagcc tgattacatt ggcgttaaag aggtgataag tatggaaaat
     3661 ggttttttgt ttttagatga aatgttgcat ggcgtccgtt gggatgccaa gtacgccaca
     3721 tgggataact tcacaggaaa accggtggat gggtatgagg tgaatcgcat catcggcaca
     3781 aaggccgtgg cgtttgctct gcgcgaggca caaatccatg cggctgcgct tggctatggc
     3841 ttgcttttat gggatggata tcggccaaga actgcggtgg actgcttcct gcgttgggca
     3901 gcgcaaccgg aggacaatct cacaaaagaa aaattttacc ccaatataga gcgagccgag
     3961 ttgattacaa agggttatgt ggcctcacaa tccagccata gccgtggaag cgcaattgat
     4021 cttacgctct accacctgga tacaggggaa cttgtttcaa tgggaagtaa cttcgatttt
     4081 atggacgaac ggtcgcatca tacagcaaaa gggatagggg atgcagaggc acaaaatcga
     4141 agatgcttgc gtaaaatcat ggaaagcagc ggatttcagt cttatcgctt tgaatggtgg
     4201 cactataagt tgattgatga gccatacccc gatacctatt ttaattttgc cgtttcataa
     4261 tgaaagtatt ggttttgtat cagattttgg atttgataaa atctatgctg gtcatggaca
     4321 atcttttact ggaaagtggt taaagcatct tttgtaatac attgcaaatt atagtattca
     4381 atctgcccag cggcagaaaa gaaaaaaacc gctgttgggc agacctttcc cacgcccatt
     4441 ttgtattttg ctggcggcgg ttttgagaaa tcaaggccgc cgttcttttc tggcagcaaa
     4501 aggtgtggcg gcccatagga ggatgccgct atgctgtttt gctattgcca tgctctaatc
     4561 cacttccacc actcaaaaaa agccttgccc ctc
//
LOCUS       DBBGSP010000122         4587 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000122 DBBGSP010000000
VERSION     DBBGSP010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.123"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            186..2855
                     /locus_tag="ACIZE9_003048"
     CDS             186..2855
                     /locus_tag="ACIZE9_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGC6094843.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3428)
                     /locus_tag="ACIZE9_003049"
     CDS             complement(2946..3428)
                     /locus_tag="ACIZE9_003049"
                     /inference="COORDINATES: protein motif:HMM:NF024793.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC6094844.1"
                     /translation="MVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDR
                     NDLAMVLIGMPGIEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKL
                     EDFSDYEAITTIIKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI
                     "
     gene            3680..4219
                     /locus_tag="ACIZE9_003050"
     CDS             3680..4219
                     /locus_tag="ACIZE9_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094845.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="ACIZE9_003051"
     CDS             4216..4554
                     /locus_tag="ACIZE9_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HGC6094846.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1419 a          790 c          860 g         1518 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgac
//
LOCUS       DBBGSP010000123         4504 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000123 DBBGSP010000000
VERSION     DBBGSP010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.124"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(614..2119)
                     /locus_tag="ACIZE9_003052"
     CDS             complement(614..2119)
                     /locus_tag="ACIZE9_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6094847.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDPFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2116..2802)
                     /locus_tag="ACIZE9_003053"
     CDS             complement(2116..2802)
                     /locus_tag="ACIZE9_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6094848.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2995..4416)
                     /gene="gndA"
                     /locus_tag="ACIZE9_003054"
     CDS             complement(2995..4416)
                     /gene="gndA"
                     /locus_tag="ACIZE9_003054"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGC6094849.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1255 a          932 c          742 g         1575 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta atctttttgt tttaacaact ctttaatctt atcagattca gaagagaatg
      121 tcaacaactt ctttgtttat tttttctaaa cgtctttgcc actcattagc agcgacttga
      181 ttatcatacc atctttattg ttatttgtca ataacttttt cgaagttttt ttcgataaaa
      241 tcaagcttta ttagctatct catccaaacg acttcgttat tataacatga catcaaaagt
      301 gcgtcaacac tattttttat aatttttagt gacaccttaa aggaatcatt tagaacaaat
      361 aataatatag caatctcttt ataaaattgc aatagaaaat tccctatttt tatttattat
      421 ttttaaacac gaatattaca gcattttatt gttttttcgt tcatctaaaa gatacttaca
      481 tttaattaac ggatgttatt ctatttaatt gttcgctagt ttttttataa tgacatccct
      541 gaatttctca cttgcttgta ttttgtacct tattctttgt tggatatata aaaaaacaag
      601 taaagcacat gctttacttg tcttctgcct ttgcgatagg aataaagatt ctaaaaattg
      661 tcccttgccc tactacactt tctgctaaga tacgtccttt atagttttca accagttgtt
      721 tagcgataga caaccccaga ccatttccac ccttcgttct agctcttgct ttatccactc
      781 gataaaaacg attgaagatc ttattaaggt cttctttggg tattccttcg ccaaagtcct
      841 gaatcgcgat ctcaaattca ttcagagtgg aagaaataga gatatggact tcttttcgtg
      901 tagttgaata ctttactgcg ttatccaata tgataatgat taattgttca aagtgattac
      961 gataaatttg cagggtcact tcttttgtca aatcatcatc taaagtgatc acatagtctg
     1021 gatataatat cttgaaatta ttataaactt gataggtgac ttcttttcct ttagttgttt
     1081 cattcgcata atgaacatct acttgttctg ctcttgataa gtctagcatc tcttgaacta
     1141 agcttttcat acggctgatt tcttgcatgc tggcgcttaa tgattcttct aatatctcag
     1201 gatcatcttt cccccaacga tttagcagac taagatgccc ttcaataatt gcaacaggtg
     1261 tccttaactc atgagatacg tcttccacga attgctcttg ttgttcaata tacaaacgca
     1321 tacggtcaag catctcattg aatatttcag ctaaatctgc caattcatca tttgtgtcga
     1381 tttcaggcat gtggatatct gattgcggat ctttacgtat agtatccatt gtatctctga
     1441 gtaccttgag tggttttaag aaataagaag ataaaaagaa acctaaaata ctacttaaga
     1501 tcaaagaaac aacttctaaa acaataagag tcaataatag cttatttcga atatcataga
     1561 aagaagataa ttcatagaag ctttgcgcat agccgatctt ttctcttgta cctttagaat
     1621 atataggctg gatagataaa aagccagttt ttccttctag tgtaacgatc gttggaactt
     1681 tacgtgtagt ctgaatcagg tttcgactgt tttcatgggt tttaaaaatc aagttctcgt
     1741 ccaaatcata aacataaaga tccattgatg gctgccctag ctcagctata aagggatcga
     1801 tcttcattaa gtttccttcg accagtgaag tatgatctac gacctcatct ccgtcatttg
     1861 tcgctttcgt cagattacga tacgtattta ctaatgtcag ttcttcatcc gagttagcca
     1921 aacgagaagc tacttctgaa atcgtacgct ctacattgtt tctttctttt gccacaatca
     1981 gattgataga tgatttatag gtaatgacag cgaaaattgt aaacacaacg aatatgaaga
     2041 aagaactcgc aaaggcccac ttgattgtca aggagggccc tttcagttct cttttttccg
     2101 attttttcgg ctttatcacg agcgcatcac ataacctgtt ccgcgtacag tttggatata
     2161 gctttcctcc ccgggaacgt caattttgtt gcgaagataa cgaatatata cgtccactac
     2221 gtttgtttca acttctgttt cgtatcccca cactttattt agtaaaacgt cacgtgctaa
     2281 taccacgttc acgttttcca ttaaagtaag cagcaactcg tattctcttt ttgttagttc
     2341 aattacttca tttccgcgac gtacgacacg gttttctttt tcgatagtca aatcgcgata
     2401 agtaatagta gtttgtttag ccacattttt atcgccttca atatcgattc gacgcaacaa
     2461 tgcacgaaga cgtgctaata attcttcgat agcaaatggt ttgacgatgt agtcatctgc
     2521 tccgtggtca agtccagata cacgatcgat cacagaatct cttgcagtca tcataatgat
     2581 tggtgtattt ttgacttggc gtacacgtct gcagacttct aaaccgttca attctgggag
     2641 catcagatcc aacaatatgg catcccactc attatttaat gccgcatcta aaccagttcg
     2701 gccgttgtag tggacttctg cgttataccc ttcatgcttc aactctagct cgacaaatcg
     2761 tgccaagttc ttttcatctt caatgattag aatattgctc atttattatt ttatcctttc
     2821 tattctactg gctttttaaa aactctatca ttataccgat aatatgctta aaaatctata
     2881 gtcattttat catggatagc aattttaaaa aagagctgaa gtctactcat aacaatcgac
     2941 ttcagctctt tcgtcctctt tttattttct catttcctaa cagccgaaag actattattc
     3001 ttcatggtac catgagtaat ggaagattcc ttctttgtcg acacgctcat aggtatgtgc
     3061 gccaaagtaa tcgcgttggg cttggattat atttgcaggc agacgttctg ctctgtatga
     3121 atcgaagtaa gcgatggctg atgagaaagt cggtacaggt acgccagctt ggacagccaa
     3181 ggcaacgacg tctctgactg attgctgata ttttttcgtg atttcaacga agtaatcatc
     3241 tagcaataaa ttttcgatct caggattttt gtcataggca tccgtaattt tttgcaagaa
     3301 tcgagctcgg atgatacatc cagcgcgcca gatttttgcg atttcaccaa atggcaagtc
     3361 ccaatcaaat tcttttgaag cgacacgtaa ttgagcaaat ccttgggcat aactcatgat
     3421 tttactgaaa tacaacgctt ctcggatttt ttcgaccaat tcttttttgt ctcccgtgaa
     3481 ctcaaaatcg ttcgtacgag acaaaatctt gcttgcttgt acgcgttctt ctttataagc
     3541 agaaatatag cgggcaaata cagattcagt gatcaatgga agtggcacac ctaagtcaag
     3601 cgcgctttgg cttgtccatt tacctgttcc tttattccca gctgcatcaa ggatcacatc
     3661 tactactggt ttacctgttc cttcatcgtc tttacgtgtc agaatgtcag cagtgatttc
     3721 tatcaaatag ctgtctaatt cgccttgatt ccattcttta aagatatcag ccatttcttc
     3781 tactgaaagg tttaaaatat tcttcattaa gtcataagat tcagcaatca gttgcatatc
     3841 tccatactca ataccgttgt gtaccatttt cacataatgt ccggctccat ttgggccaat
     3901 atatgtgaca catggtgctc cgtcttctgc ttttgcagaa atttgctcta agattggtgc
     3961 aactagcgca taggcttctt tttgtccacc aggcatgatt gaaggtcctt ttaaagctcc
     4021 ttcttcacca ccggaaacgc ctgtaccgat aaagttgatg ccagagttgg ctaactcttc
     4081 attacgacgc atcgtatctt taaagaatgt atttcctccg tcaatcaaaa tatcgccttt
     4141 atcaaggtga ggaagtaact cttggattgt tgcatctgtt gccggtcctg ctttgaccat
     4201 tagcaagatc cgacgtggtt tctcgataga ttctacaaat tcttcgattg tatatgttgc
     4261 tttgaaattt ttatctgggt gttcttctac tacagcggtt gttttagccc ctgtacgatt
     4321 gaataaagcc actgaatagc cgcggctttc tatgttcaag gctagatttt tacccataac
     4381 ggccataccg acaacgccga tttgttgttt tgacatatga actcctccta catacgggat
     4441 ttctccctaa tctcttacat tatagcttaa cacggctaca ttgcaaacta aagaacaaca
     4501 tatt
//
LOCUS       DBBGSP010000124         4477 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000124 DBBGSP010000000
VERSION     DBBGSP010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4477
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.125"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            598..744
                     /locus_tag="ACIZE9_003055"
                     /pseudo
     CDS             598..744
                     /locus_tag="ACIZE9_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
     gene            complement(832..1125)
                     /locus_tag="ACIZE9_003056"
     CDS             complement(832..1125)
                     /locus_tag="ACIZE9_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HGC6094850.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            1162..1347
                     /locus_tag="ACIZE9_003057"
     CDS             1162..1347
                     /locus_tag="ACIZE9_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094851.1"
                     /translation="MLEYSGFFIKAVTLKKDIIIVLFFLLLLIGRFILIHYSPLPIIK
                     EKTGSGCSNYMLRKKNP"
     gene            complement(1528..2706)
                     /locus_tag="ACIZE9_003058"
     CDS             complement(1528..2706)
                     /locus_tag="ACIZE9_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC6094852.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(2810..3124)
                     /locus_tag="ACIZE9_003059"
     CDS             complement(2810..3124)
                     /locus_tag="ACIZE9_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094853.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            3231..3446
                     /locus_tag="ACIZE9_003060"
     CDS             3231..3446
                     /locus_tag="ACIZE9_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094854.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(3746..3988)
                     /locus_tag="ACIZE9_003061"
     CDS             complement(3746..3988)
                     /locus_tag="ACIZE9_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094855.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(3975..4403)
                     /locus_tag="ACIZE9_003062"
     CDS             complement(3975..4403)
                     /locus_tag="ACIZE9_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HGC6094856.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         1418 a          841 c          663 g         1555 t
ORIGIN      
        1 ataaaaaatc atcaaataat cctttacacg ttattctaaa tttaattttt attattttat
       61 tgatgtatag aaagtttggg gctttttttc tctttttatt ctaaggttat tttagtcttg
      121 tcctttaata caaagatttt atttttaaat aaaaaatact ctttttttac gattattgaa
      181 aaaaaaagat aaaacttgat taattgaagt attgcttaaa tttggaagct atgagggaag
      241 aataaaagag ttaggacggg attatctact atttttcttt gttttaaata tttgttatct
      301 ttgaacataa aagagaaatg tgtcgactgc agtgttgtgt ccctcatcac gaataaacgg
      361 tgttcaatta gctgatcttg tattcactta aaaaatggta aagtacgagt tgctattccc
      421 cattttcaat tttctaacgc tcaggacaaa atactgtttt cacaacctca ttggaataaa
      481 agcatatata ttgtttcaag aacgaaatct tgttatcttt ttaaagggca tctgtccaaa
      541 atctaatttt aggaggtacg ttttggtatt tattcgtaca aataaaagag aattatcttt
      601 attcatgtaa cgcatccaat tgattttttc atgtacgctc ctggaacgat tttactgacg
      661 attgcttatt taactgcgaa tcgctcatta gcttttatca tagctatcca tattttgaat
      721 aacgttcttg gctttgtatt atagatacag atgacaaaaa aagttcaagt atgcggtgta
      781 gaaccaatat cgcatacttg aacttttttc aatgagtata aattaaaact tctaattttc
      841 aattcccatc atctgatatg cccgaccgtc tgaacttctt ttgaaaaagc caaatgtgat
      901 tagataacgt ctttgttcga cataatcgcc actagaaaat acgttcagca gtatcgaatt
      961 aacctctgtt tctgtataag tcactccatg gtcaaagcgt ttcaagactt ctttcaatag
     1021 gatgtatttc ttttttgttg aacttggtac ttgttttact tttccatcat tcatgaatgt
     1081 gtctaaaact ttcatctttt cttgctccgt ataagtataa accatcttct ttctcctttt
     1141 gattctaaga atactccatt tatgttagaa tattctggat tttttattaa agcggttact
     1201 cttaagaaag atattatcat agtgctcttt tttttactac tacttatagg tagatttatt
     1261 ctaatccatt attctcccct accaataatt aaagaaaaaa ctggatcagg gtgttcaaat
     1321 tacatgctaa gaaaaaagaa cccttgaata ccaagggttc tttctcagtc tgataacaat
     1381 gattaacgac ggatttcttt gatacttgtg aaaagtcgtt aaagtattga tataaaagga
     1441 tttttattac ctctgactac atattgacta atttgttaaa aaatcgtttt tcaagaatcc
     1501 tgtaatacca gtgctttcac cgttttttta actctctaaa gaactaaaag caatcagagg
     1561 ttttaccttt tcatttgacg ttaagtggcg ataaattttc gaagttgttt ggtcagtatg
     1621 gcctaagcga tctttcaaga cttcccagct acagtgttcc gctactaagc ttgccattgt
     1681 atgacgagct aaatgagtat gaaatggctt attaattcct gagcgattca cgcaccgttt
     1741 gacgtgatca tttacatact ctcgacgata aggaacacca cgtttactag aatcaagata
     1801 cacaaacaaa tatgtttctt ctataataaa cctgtaatgt tgcctcatct cacccaaagc
     1861 cttaatcaac tgttgtagct tttccataac tagaggagtt actagaactc gtctagcaga
     1921 actaactgtc ttagtagttt caattcgaaa atccttactc ttacctttaa ctgccgtttg
     1981 cttatagaac agaatttcat ttcttttgaa atctatatct ccaggctgta gagcaagcgc
     2041 ctcgctgact cggcagccag tgtaaaatag aacatggaaa agtacagaca tcggtaattc
     2101 ctcatgaaca atgccataat tcaaaaaagt tctcaattca tcgacagtaa gaaacttgtc
     2161 ctcaatatta tttatggctt cttttaaatc agttaccgtt aactgatatt ttggcattct
     2221 cacagacttc attggatttt cacttatcaa attctttctt tgacaatatt taaaaatcat
     2281 atttagaact tgaataagtg attgtaaact atttttggca tagccaacat ttgttccatt
     2341 aacgccacat tcctttaagg taaaaagcaa ttcttgaagg cactctggtg tcaaatcaga
     2401 caacttttta tcaccaatcc atcgaacaat aatttttaat tgttcctctc gcttatcata
     2461 ggttatttcc ttttgttcat ttaacgaacg gtaatattgg aaccattgct cacctacaac
     2521 actaaacttg tcattgcttg caacaatttt tttcttaagc ctttgttgtt tctccatttc
     2581 cagataagcg agttgcgcct cacgttttga attaaagcca cgtcttgttg ttcgatatgc
     2641 ttgaaagtac catgtgatcc taccagtaga actgatttgc ttcttgaatc gatctgtttt
     2701 ttccatttat tgattcctcc tattttgaag gaacccaaca agcagaaacc ctttggaaat
     2761 ctttctatct atgtcatcat tgtaccgcat cttagaaaga aaatgtaact tataaagatc
     2821 gaagtagtcg caatttttct cgatagtcat tcgaatcact ctttctcatc cattctaaaa
     2881 catcatcacg aaaatagtgt cctcgaatcc cgtaccaaca gggaggaaac tcaccaagtt
     2941 ttactaaacg gttcagtgta ctatcactta tctgaaatag tcgctttaaa tcagtatttg
     3001 ttaataccag aggtaaatga ctgactgcaa gcaatttttc cgtgtaatct tccagttttt
     3061 tttgtaaaat tgaatagaac tctatttcca gagaattaac atttgtttta acttccaact
     3121 ccatcaccct tctctctcaa aatcaaaacg accaccacgg taccccttaa aattgtaaaa
     3181 aaacactcca gtactccatc aaaacggact agaaaagagg aatttttaat atgaaacaag
     3241 gaattgcaga cataaaaata attaaagaaa ttcttgaaaa atctacggct aatgcaatag
     3301 cattcggaac aggaatcaac ttgagtacag taaaaaaact taaaagtgga gagagagctg
     3361 aagaaaaatt aaatcttgcc gatgctatta aaatcacaga atttggcatg aaaaatatgc
     3421 caaccaaaat cgaaatatgg aaatagtagt ttttctgatc tatcagctgt tttgccaaag
     3481 cacataggaa tctcacctcc ccccagtaat ggcgggccga tttggttacg gaagtatcat
     3541 tatcgtagtc gcgattctca tattaaaatt tgtcgcttaa aagctaacct tgtcatggcg
     3601 taactagaga atcaaaatct acatgtactg atagatttgc tattcatttg tcaaagagcg
     3661 ctaggctatt ttcagcctat ggaaatcctt tattttgacc cgataaaaaa cttccataga
     3721 atgaaaagga aagggaaaaa atactttaac gagttgtatc aaattcaagt atcttctcaa
     3781 tcaattttgt ttccagttgt ctacgcatat attcatctac atacataacc attccttttt
     3841 cttcttcata aactggtttc atggctaacc gtgaaatata attttgatat tttgacagaa
     3901 cgatggacat ggcaattgaa tcaccagaag ctgcggcttt gattgtcgtt agtggtatga
     3961 atggtatata tcgtttattt tgcttcatat ttgacaccca aatactttcc tagctcttcc
     4021 aaagccattt gtcgttggta ccaaacactg ccgagacttt tcccaataat atcgccaatt
     4081 tcacgatcat taagaccgat gaagaaggac ataaaaatga tttcttgtct ttgactaggt
     4141 aatgctgcaa tcgcatttgc caactcctca ttggaaataa agattttcat accaaggaca
     4201 ataaaagtac cactactatt caaatttggt tccaaataat agaactctgt acctaaccct
     4261 ttttgttcca atatttccat tgatatttgc cgttggcgaa atctagcgta cttcttttga
     4321 atatttaacg cctcattgca gactactttc ttacaaaaac tgtcaaacgt atgttgaatg
     4381 tgggtttcct ctgagtcgcc cataatattc tccccctcaa aaaattcatt caactcgttt
     4441 tacttctatc cctttccatt attactacaa tctagga
//
LOCUS       DBBGSP010000125         4461 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000125 DBBGSP010000000
VERSION     DBBGSP010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.126"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            574..1008
                     /gene="bacA"
                     /locus_tag="ACIZE9_003063"
     CDS             574..1008
                     /gene="bacA"
                     /locus_tag="ACIZE9_003063"
                     /inference="COORDINATES: protein motif:HMM:NF041453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin 51 precursor BacA"
                     /protein_id="HGC6094857.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            2298..3221
                     /locus_tag="ACIZE9_003064"
     CDS             2298..3221
                     /locus_tag="ACIZE9_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HGC6094858.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            3237..3776
                     /locus_tag="ACIZE9_003065"
     CDS             3237..3776
                     /locus_tag="ACIZE9_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HGC6094859.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         1664 a          667 c          758 g         1372 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacagagaa cttaaattga attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaagaaacg gataaataat aaaaaagact
      181 gctcttccga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcaacgcgct
      241 tataaagcgc taccaaaaat ttatcatatt ttatgaaaaa taacaatcca gtaaaaaatg
      301 actggtaaaa attcacaaag aaacggaaag aagcaactgc agaaaatcaa gccttaaaaa
      361 gagcttttta cctagaccaa ttaaaaatca caaagtgagc ccctgtatcg gttgatacaa
      421 gggctacttg gcatactgta cattatgtct actaaccttt aaaataacac gttttataaa
      481 ataaaccctc ttgacaatat ttaattttct gattattcta aatatataca gaaagcgctt
      541 tcctaggatt ttatatctaa ggaggaagta acaatgaaaa ataaaattat taaaattatt
      601 acttgtctat ttttgttcgg tatgattgtt ggagcaagta ctccgttaaa tctgtttcct
      661 tttagtgcta gaggtataaa agtggaagct gcaagttcac gatataatca taatcatcgt
      721 ggatttactt gctataaaat gaactattat gttactaata aaatgtgtag agatttgaaa
      781 aaaaattata ataagctaaa gactcctgct caaattgcat cttttattcc tattggtgga
      841 gttggaacat gggttattac aaatgctttt agtagtgctg ttgatgcaat gaatgtcttt
      901 gtaagagctg caaatcaagg aaaaggtgta caattaacat ataatgctca ctttagcaat
      961 acaacatcat atcaatacaa tgattacgct cgttatgtaa taaaataatc agaaagtgaa
     1021 actatctcat gaataaaaag attttagctg taattatttc aataatagtt ttaatcacta
     1081 tgttcttcat atttaggcta attttcaata taagcttaca aaaaagtatt ctttatctaa
     1141 ttcctatagc atttatctta gcaattttta gaagtattta cggaaataaa aactctaaat
     1201 agctaaaaat aaatcatact aaattttaca aaaagtggct agcattttct agccactttt
     1261 tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc cctttgacaa
     1321 gcggttattt gcaccaaata cggaggtatt tggctagcaa atatagagct tgccaaaccc
     1381 ttttagtgag ttttgtagaa agtaccttta aaggtacttt cacattacga acgatacgtc
     1441 cgtaggacgt actgaaaggg tgggacttat gagcaaatta atgcaaaatt tggctagcaa
     1501 aaaagctaaa aaatatatgc taataatcga gcgaaataaa cactttttca agtgagcgaa
     1561 tccgccatga caaagctgaa gcagtttatt tcagctttgt catggcgtgt gccgactttt
     1621 ttaaaagtct aggcacacga gcaaatatct ttatcaagct ctaatttgcg ttttaagacg
     1681 tttgaaacgc ctaagtatat aaatatataa gaataggttt aagagtgctt aaatcgaatt
     1741 ttagagggca tttagacaat tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
     1801 ttttaagaac aagataaggg atttatacta ggactgtctt aaaatgtctt aaacgaacgc
     1861 tcagagcttc tcaaagggtt ccttatgaac ggcttttagc aaaggagccg gaggcgactg
     1921 cgcagtataa tgtgagagca gagcgatcac acctttttag cgaaccgtag ggagcaaggt
     1981 ttggaattgg cagttttgat aaattcgcga acctgtttag agaaaaaagg agtgattttt
     2041 taggcgggaa aattagcctc ccctcttttt atatctcttt ttatatctct ttttatatct
     2101 cttttatgtc ggctgtgtcc ttactctccc aagcaattca gagttttttc aagtaggttt
     2161 tctacgcttt tcaagtaggt tttctacgct tttcaagtag gttttctacg cttttcaagt
     2221 aggttttccg acattattga gtatttttat aaagtatgtt acttttattt catactttat
     2281 aaaagtagga gaagcttatg gcaaatgaaa ttgtaaaata tgaaaataga ttaaatcata
     2341 ttcctctgag aaaatttaat agtcgtgaaa tgaacttatt tttttcaatt gcttcacgtg
     2401 tacgtgaaaa aggtgtagat gagattattt tttcatttca cgatttgaaa aaactaagcg
     2461 gttatacaga acgtggggaa caatttataa aagatcttag tagcacgtat gacaaattat
     2521 taagtattaa tgcttggaat gatgatggaa atactttaac taaatttgtt gctttcacaa
     2581 aatatagcat tatacgagat aaacaacttg ttataatttc agttaatcca gaatttaaag
     2641 gactttttaa tcaattaaag aactggacaa gatttaatct agagcaattt actaatttgg
     2701 atagcacata ttcaaaaact atgtttcgat tattaaaaca atatcgaact caaggctgga
     2761 ctgaattttc caaagaaaaa ttttttgatt tactagatat tcctaaaagt tattggaata
     2821 gtccgtcaaa tattgacaaa tttatcttaa ggccaattaa agaagaactc actcccttat
     2881 ttaaaggatt aactattcgt aaaaaatatg gtaaaggtcg aggtaaacct gttatcggtt
     2941 atcgttttac ttggaaagct gaaattaacc atgctgacga tttttccaaa gggaaacaag
     3001 aagatttacg tataaaatta tttaatattg atcacaatgg agaattaaca cgagaagaaa
     3061 aatggcgcgc taaagatcga atactaaatc ttcccttagg cactcatgaa gctgatttta
     3121 aacaacaaca acaaactgaa gaaaaacagg cagaaaaacg agaactttca aacaaactca
     3181 aacaagattt actaggaaat ttacaaaact tattcgatta agcttaagga gtatttatgg
     3241 cagataaaac aatcaaagaa cttgcggaag aattaggagt tagtaaaaca gcaattaaca
     3301 aaaaagtttc tgacaaaaat cgaaaacttt ggtttgcaaa aaacggaaac aagtttgtga
     3361 ttaacgaaac cggtcaaaaa gctataaaat caatgttttt agtcgataac gcaaacttaa
     3421 atcgaaaact agttggcgaa aaatcaaaaa ccaaaaacca taaaaacacc aaccaagttt
     3481 ccgaattaaa actcctttct ttcctagaaa aacagttaaa tcgaaaagat atacagctac
     3541 aagaaaaaga taatcaaata aaacaaatgc aaaaattact cgaccagcaa caacaactca
     3601 ctctacaagc gaaccaacaa attgagaacc tacaagaaca gctccattta acttatacag
     3661 aagaaactcc aacaaccgaa tcaactgcct tttctgaaaa aaaagcagac aatacacaac
     3721 cacttattga aaaaaagtgg tggcaaattt ggaaatctaa tagaaccaat ctctaaaatt
     3781 ttctagaagt tagttcggat agtagaggaa aaagttgtac tacctgatgg ggagatcact
     3841 caaattttta tgagaaagaa aaaatagttt acaactgtaa acaatcaatg tttatagttg
     3901 taaactatca aactatatgg tgacttattg cttaaaatag gttgaaatct cactcaattt
     3961 ttggtggaaa aacaaaataa attctaatcg attttgttga aaaagtcata aaaaaacaaa
     4021 tgtgatttta acaaaatttc aaaaaaatcg tttgaaattt cgtttatttt ttttgagaat
     4081 tttgatcatc gtagggtcat tgtagaatca ttatgagatc atcgtgggat catcgaataa
     4141 agtatgggaa aggcttgcgg tgcttggtat taagggcatt ctccgcctcc caggttcttg
     4201 accattttct cttataagtg ggatttttac cacgttgaga gaaaatggtc aagaacctgg
     4261 gaggcggaga aaacatacca agcaccacaa gcaaaaaaag ttagagtaac ttccaaaaaa
     4321 gaaaaatttt ttagaacaac ttttgaaaat ttaattttga tttatatccg ttcaatttaa
     4381 acatttgata aactgaaggc tagtatttaa aatgtgtata caagtggtag cgttaaaaaa
     4441 agtggaggta taacctatgt t
//
LOCUS       DBBGSP010000126         4438 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000126 DBBGSP010000000
VERSION     DBBGSP010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.127"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            89..406
                     /locus_tag="ACIZE9_003066"
     CDS             89..406
                     /locus_tag="ACIZE9_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HGC6094860.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(497..862)
                     /locus_tag="ACIZE9_003067"
     CDS             complement(497..862)
                     /locus_tag="ACIZE9_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094861.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1070..1552
                     /locus_tag="ACIZE9_003068"
     CDS             1070..1552
                     /locus_tag="ACIZE9_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094862.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1749..2639
                     /locus_tag="ACIZE9_003069"
     CDS             1749..2639
                     /locus_tag="ACIZE9_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HGC6094863.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(3042..4337)
                     /locus_tag="ACIZE9_003070"
     CDS             complement(3042..4337)
                     /locus_tag="ACIZE9_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGC6094864.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT         1456 a          734 c          860 g         1388 t
ORIGIN      
        1 ttttaaaaca tcacaaggaa aaacttaact atggtattat ctaaacataa ttttttcggt
       61 atttaatatt taattaggag gtaatatttt gcttttttat agtaatttta tcttaatagt
      121 agcgatatta ttacttctga atatatggat ttttgatagg agtagaaatt caagtatagg
      181 ttttagaact aaacgaagtt tgtcttctaa aaaaaattgg gtatactcac aaactatttt
      241 ttatggagga attgttttaa ttagtttact ttcttcaaca ctttattctt tgaatattat
      301 agatgtttcc acctcaaatt caatatctat tattggaatc attattgctg caattattac
      361 acaactgttt ttagtgtttg gagagaagaa aagaagtaaa aaatagaaaa actagtgata
      421 gttttggtga tataagaaaa acatatatgt ataaaaagaa gaaagtagct tctctttgta
      481 catatatggt ttgtttttat ggatgccgag cttttttata agataaggct accgcccata
      541 acgacccaag gatttgtgga actaagtaaa tacctgcaag aagcaagatc agctgggtcg
      601 gttttaaagg atgatagaag taacgccatt cagtaaaatt ggcgcaaaat aaataggaag
      661 tgacagtaga tataatattg gcaatgaata aagatataat acgcctgttc ctttgaaaat
      721 aatatccagc aaaaagagat aaaaatatca atgtgatgaa cccgcttacg gaatgataac
      781 gaaaatcaag cagtaaggcg aaatgcacat aaggaacaaa agataaaagc aacggaaggt
      841 ttttccagca agtttttatc atctttcatc accacctaac aagtgttatt attttgttag
      901 ttttattgta aattgaatcc tgcaataatc aattactttt tcattatttc tagattaaat
      961 gaataaactc tcatgccatt atctctaaaa aaaaagtttt tccccctaat ttttttagat
     1021 agaaaattgt atagtatgat gagagaaaaa gtagtttggg ggaacgttaa tgagaagaaa
     1081 agcagtaatc gatcggcttt atttattttt ttggtttttt cctatcgttt tgctaccttt
     1141 tacatgggta aatgctgttg tacaaggtgc ggagatatta ggcctgatcc aaggaagcgg
     1201 atttgtggtt tctaggaatt ttccagcttt gattgttttc tatttagtga taagtgtagg
     1261 tctcttatta ccaaaatctc tgatcaatca ctacaattgg cagctgcttt acttttcttg
     1321 cttattagta tttacatcta cgttttcttt gctgcctcgc ttgattatcg gccctaatgg
     1381 tttgagcgag agtggattga aggatttagc ttattcctcc atgtatttct tgacgatcaa
     1441 accatggttc tatttagtaa ttgcctcatt tattcttgca acattttttt acttctggac
     1501 agaaatcagg ataaaaagtg aacgatctgt atctataaaa aataactatt gatggtggat
     1561 catcagtaaa aaaacatatg agctgcgtaa aatgcatgtt tctcatatgc tttttttatt
     1621 attatgtaaa gaatgcgaaa aacgtttaca tgatttttac ataacttaac tatattttta
     1681 cagcaaccat acgagggatt tacagtcgac tgataaactt tagttgtaaa taagaaagga
     1741 gcaataaaat gaaaaaagta ttgtttactc taggtatgat gggaattctt ttagccggat
     1801 gcggctcagg atcaggaaat acagatggct ctgccacaca aaataattca agtgactcaa
     1861 atgaacaagt aaaaatcgtt gcggtaggtt cgacagcatt acagccgtta gtcgatgcag
     1921 cacaagaaag ctttgtacaa gaaaatccaa attatcaaat ctctgtacaa ggaggaggaa
     1981 gcggaactgg tttgagccaa gtcgaagctg gagcagttac tatcggaaac tctgatgtat
     2041 ttgcagaaga aagagacgga gttgatgctt caaaattagt ggatcataaa gtagcagtgg
     2101 tcgggatggc accaatcgtc aataaagata cagatgtcaa agatatcacc aaacaggaat
     2161 tgattgatat ctttacagga aaaatcacta actggaagga agttggcggg aaagatcaaa
     2221 aaatcaacgt cgtgaaccgt gcaaacggca gcggtacccg cgcgacattc gaaaaatggg
     2281 gactggatgg tgctacccct gtgcagtccc aagaacaaga ttcatcagga acagttcggc
     2341 agctggtaag tcaaacacca ggagcaatca gctatttagc tttctcatat ctcgatgatt
     2401 ccacacaagc actaagtatc gacggtgtag aaccaaaaga agagaatgta gcagataaca
     2461 gctggggaat ctggtcatat gaacatatgt acacgaacgg aaaaccttcc cctgaagtcc
     2521 aaaaattctt agactacatg atgacagaag aaatccaaga aggacctgtc aaagaattgg
     2581 gctatttacc aatcacaatg atggaagtag aacgtgatca cgaaggaaat atcaaataac
     2641 tagcagataa acatgccacg gtagtcgtta ctattaagga aaaatcaact atgtttcccc
     2701 acatatacat ttttccttta attgtgaaaa atagttcctc atattttgcc gttttttgag
     2761 ctaataccga gggtcagctg attgaacacc gtttattcga aaaaaagagc tacgacatag
     2821 aactgtcgta actttttttg gctcttcgtc aaatcgtgtt ggtgaagaca aatttgaata
     2881 aaacttagac cgatatgcgg cgcgttctgt gcgccgcata tttttttagt tttcaaagat
     2941 cagaccttgt tgtaaaggct ctttgtcaaa tgatgttggt aaagagaaat cttagaataa
     3001 tttggacaga acagaaagaa gaaaacctct ttctgttctg tttatttggt taaaaatgtt
     3061 ttgccatgac gaatcataat tcgtagtttg aaattgtaaa agttgcgaaa gccgtacgca
     3121 ttgcgtttta atactttgat gtggttgttt aagcattcca atggtccgtt tgaatagctg
     3181 tagtgaagcg cattttggat ctgtggcaga aactttttaa acgttcgtaa agtggttgta
     3241 taggtttctg gcagaccgct aatgtctcta gttaaacaat cctcaaatag tgactgatct
     3301 cttttcttta ccgcataaag aatgtcttgg tataactgat agccttggcg taagttggga
     3361 caagcagcta acagtcgatc ggcaatctca ctttcagtca aataatcttt aaaactggca
     3421 cgccaaaccc gtttttcata gtttaacttt gcttcttctt tttgtaggag tttccaatag
     3481 cgcttcaatt ttttccctaa ccctcgttga gagtgggaat ttcctttaag tcgtaccgtg
     3541 gtttctttca ctcgatgatt caagaaagtt ctgccaatat gttggacgat gtggaaacga
     3601 tcgatgatca actgagcatt cgggaaaagc tttttcacca acgaaacata aggcgcatac
     3661 atatcaataa caatcaattg aacggcttca cgagtcgcta atgaaaaccg agaaaaatag
     3721 cgttctaaat aaggcaagcg tcgattttcg acaatatcca ataatgcatg gctttgtccg
     3781 tccatcatga taaaactcat tgcactggca acacttcgaa ccgatttgaa ttcatcaaag
     3841 cataagacct ttggcaaagt ctgtttgaaa ggattcaatg ggcggtagaa tcgcttcatg
     3901 acacgataga ccgaagaagt ggaaatattt ttctgacgag cgatttccgt catggaagta
     3961 ttctctttta agcgagcaat gacagaccaa cgaacttttt gactaatgaa acagtgtttt
     4021 tcagcaacag aggtatccgc tacgaatgtt ctttggcaag acttacattt aaatcgttgt
     4081 ttcttcagct ccagataagt gcgatactca gacacatcat tcagtaacaa ccgaacggtt
     4141 gtcgtccccc aacgaatgat cctagagggg acgacacaaa gacaatggga acactcttct
     4201 ggcttgtaca gaagagttcc tttgtaaatc aagcaaattt gccctttgta tttttcttta
     4261 gttaaacaat tttcctcgaa atagatattt aggtctagaa tatttagggt atctttgata
     4321 agctgagtat gagacatctt gaatcctcct atgaattggt agccaaatta attctaaagg
     4381 atttcagggt gtcttttcta tattttttta tacaaaaaag atgttggtga agttcacc
//
LOCUS       DBBGSP010000127         4415 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000127 DBBGSP010000000
VERSION     DBBGSP010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.128"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            58..912
                     /locus_tag="ACIZE9_003071"
     CDS             58..912
                     /locus_tag="ACIZE9_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGC6094865.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1009..3258
                     /locus_tag="ACIZE9_003072"
     CDS             1009..3258
                     /locus_tag="ACIZE9_003072"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGC6094866.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3261..>4415
                     /locus_tag="ACIZE9_003073"
     CDS             3261..>4415
                     /locus_tag="ACIZE9_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6094867.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1556 a          625 c          805 g         1429 t
ORIGIN      
        1 taataatata aacataataa aacaaaaatt atccaaatct aacataggag ggtggatatg
       61 gaaaattcta tatatttagt aacagaacct aacactcagc tgaaagattg ttactttaat
      121 ttttgtgggt attcaaaaac agaacctaga catagttttg gaccagctat tcgagaacaa
      181 tacttaatac acatagtgct agaaggtgaa ggctattatt caattaatga tcaaaaatat
      241 tttctgaaga aaggccaagg atttgttatc ccaccaggag tatctacttt ttatcaagca
      301 gatgaaaaaa atccgtggtc atatgtatgg ttgggtttaa gtggcaatct tgtagaatac
      361 tatctaaaag aaattggtgt tggaaagaat catcttacct ttaaagtcga aaatttaaat
      421 tcatttaaag gattaatttt tgaaacttta tcgtatgatc aggacaatct agtcagtgaa
      481 ttgtccagac aaaaacaagt ttataaattt ttagaactcc tcttaaattc agctagttat
      541 ctgaacgaag ggataattac taaaaagatg aatccttttg ttcgtcaaac aattgaaata
      601 atacgtgaga atgcgtatca aaaattatct gttaaagata ttgctgtcag tctatcgata
      661 cacgaaaatt atttatcacg attgtttaag aatgatatgg gaatatcaat aaaagagtat
      721 attagtgaaa tcaaaatttc tattgcaaac gatctgttat catcaactga atattcaatc
      781 cagcaaatca gtgacaagat aggattctca acagtacaat ctttttctaa agcctttaag
      841 aaagcaaatg gtgtttcacc gggagtatat cgaaaacgta gattaggtct aggaatcatt
      901 aatggtgaat aaactaaaca tttgattttg ataaatattc gttactttaa acgcttacta
      961 tttatgtgag cgttttttat aatgcaataa agaaacggag gagagcttat gtataaggat
     1021 aatgaaatga atattattta tcgatcagaa aaccaacaat ttcatttgtt taatcaggag
     1081 ataagttaca tttttaagat atcggaagat ggtaaattat tgcatttata ttatggtgag
     1141 aacttaccag ataatgacta tagtcatcta attgagatgc atcatcggcc tatgacaacc
     1201 tatagaaatg aaaacgattt gctatattcg ttagagcact taaaacaaga atttcctgaa
     1261 tatggtacaa cagattttag acatcctgct atttcattac tacagaaaaa tggctctcgc
     1321 ttatcagatt ttgtctatca agggtacgaa gtggaagaag gaaaacctaa actagaaggt
     1381 ttacctgcta cctatgttga taataatgat gaaagcaaaa cattgaaagt ttatatttta
     1441 gattcagtta caaatgttca agtagaatta ttatatacaa tttatagaga ttatcctgtt
     1501 attactcgta gcgcgcgagt tatgaataaa ggaaaagata ttcaaataat cgagaatatt
     1561 agcagtttat cattggattt acccgatgca aattatgaat ggcaacaatt atctggtgct
     1621 tggggtagag aaagaactat taagtcgcgt actttacaac aaggaattca atcaatcgaa
     1681 tctactcgag gtatttcaag ccatcagcat aacccatttg ttactttaaa aagaaaaaat
     1741 actgatgaaa atcaaggaga agctattggt gcagcactag tttactcagg aaacttctta
     1801 attcaagcag aagtagatac atgggatgtt actagactac aagttggcat caatccattt
     1861 ggatttaatt ggaaactcaa tccaggagaa atatttacag caccagaagc gattctggtt
     1921 tattcaagta agggtttaaa tgccatgagt caaacttttc atcaactatt tagaaaacgc
     1981 ttagctcgtg gtaagtggcg agaaaaagac cgtcctgtct taattaataa ttgggaagca
     2041 acatattttg attttgacga agaaaagttg gtaaatattg ctaaaaaagc atttgatgtt
     2101 ggtattgaat tatttgtatt agatgatggc tggtttggag aaagagaaaa cgattgtgca
     2161 ggattaggag attggcatgt aaatcctaaa agactaccta gaggaatcgg cagcctttca
     2221 gaaaaaattc gtagttttgg tatgaaattt ggtttatggt ttgaacctga aatggtgaat
     2281 aaggatagtg agttatatcg cacacatccg aattggatta tttctacacc taatcgaaaa
     2341 cctaatcatg gtaggaacca atatgtatta aattttgggt tagatgaggt tgttgaaaat
     2401 attttcgatc aaatgtgtaa aatcattgat gaatcaaact tagattacat taagtgggat
     2461 atgaatcgtc cattgactga tgtatttgac agtcacttgt cagcagatca acaaggagaa
     2521 gtattccaca gatatgtact aggcgtatat cgcttatatg aaaaacttat aacaaaatat
     2581 cctaacatac tatttgagtc ttgttcatca ggtggtgggc gctttgatcc tggaatgctt
     2641 cactatgcac ctcaagcttg ggctagtgat gattcagatg caattgaaag gttaaaaatt
     2701 caatatggaa ctagtatgct gtatcctctt tcgtctattg gtgctcatgt atcaattgtt
     2761 ccaaatcatc aaacaaaccg tataacacct ataaaaacta gaggaaatgt agcttttttt
     2821 ggtgcatttg gatatgagct tgacttaaat gaattaagtg aaggcgattt gaggattgta
     2881 aaagaacaaa ttgcctttta taaaaaatat agaaccataa ttcataatgg tactttttat
     2941 agactattat caccattcga tgatgataat caaaccgcgt ggatggttgt tagtcatgat
     3001 aagaaaacgg ctattgttgc tcattataaa acattaaatg aggtaaatgc tccttaccgc
     3061 cgactgaaat taaaagggtt agataatgac ggactttata atgtaggaca aaatagtttg
     3121 cgatctggaa tggaattgat gagagcagga ctagtctgtt cagatgcatc tagtggacaa
     3181 ataaatgatc agaatcgacg cccagaaaca tttgattttg attccaagat ttgggttata
     3241 acacaggagg aaaagtagag atgaataacc aaaaaagctt acttcaaaaa ggagcaatct
     3301 taagtatttc actaatgtta acaagctctc aagcaattaa tggtgttatt ccacaaatga
     3361 aacagtcttt ggggatatca caaagtcaaa gtgaactttt aggaactgca ccaagtataa
     3421 ctgttatttt gtttatctta ttatctagtt actttgccaa aagaatagga atgaaaaaga
     3481 caataatttt aggtttatta ttagctggta taggaggaat tattccagta tttacagcta
     3541 ccttccaaac cgttcttatt agtcgagtaa tattaggtgc cggtttagga gtatataatt
     3601 cattggctgt gacatatatc agctctttat actctggcaa tactagagca acgctattag
     3661 gtattagaaa ttcaatggaa gctttaggtc agacaatcct tatttttctt gctggagttt
     3721 tagtgaacat taattggacg gcttcgtttt tagtctatgc aattgcgttt cctgtagctc
     3781 tcttattcgc gctaaaagtt cctgaaatta gagatgaaaa tagtgacata cctgaaaatc
     3841 atgtaaaaga aaagatgaat ccaatggttt ttgccctagt tctatttgca atcttactcg
     3901 taatgaatag tattgctatt tctgtacgat ttgcatcaat tgcaactgaa attaaagggg
     3961 taaactttaa tgctagtaac tatttagctc taatgcctat cttaggaata ctagcaggat
     4021 ttatgtttgg accaataaat aagtggatag gaaaaggaac cctatacttg ggaattatat
     4081 tctttataat ttcaaatttg ttaattgctg tgtcaaacgg taatatgacg ttcctgctaa
     4141 cgggtttatt tttatcaagt ataacaggat catggtgctt cccatttatc tttagtaact
     4201 tagataaagt cactacaaag aatacaatta attttgctac ttcattgatt tttattggct
     4261 gtaatattgg taattttata gctcctattg ctatgcaatt agcacaattt ctaacaagaa
     4321 gtacaaattt gactgctcca ttttttgtat tcgcaggaat atttattgtg atcctatttg
     4381 taacattttt tgcgacaaat aaaaaaaata ctaga
//
LOCUS       DBBGSP010000128         4408 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000128 DBBGSP010000000
VERSION     DBBGSP010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.129"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(205..660)
                     /locus_tag="ACIZE9_003074"
     CDS             complement(205..660)
                     /locus_tag="ACIZE9_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LMxysn_1693 family intestinal colonization
                     protein"
                     /protein_id="HGC6094868.1"
                     /translation="MKKQLFKTFLLSTSILTFGSAITPSGAVFANENNISDIATYSDD
                     EYYYVLDEPVIQTRTWSKPQSWSIAKGSRTYLGIETHSRGTKLSVSANVFGMKIEIAR
                     NTSASGKFKKYRQNARITVTYRVYRKVDNKYIRTQTSTANTQYIDYIPA"
     gene            complement(1068..1238)
                     /locus_tag="ACIZE9_003075"
     CDS             complement(1068..1238)
                     /locus_tag="ACIZE9_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094869.1"
                     /translation="MTRKKLIFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            complement(1254..1724)
                     /locus_tag="ACIZE9_003076"
     CDS             complement(1254..1724)
                     /locus_tag="ACIZE9_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HGC6094870.1"
                     /translation="MTDKSIKEFAEELGVSKQAIRKYFDKLPTKLTPKLIGGKYVISA
                     KAQEFIKNSINQINEVDTEVDSLVDSILIAELKEKNKQIDHLQGVIEIQQKLLDQQQQ
                     LTLQANQQIDKLQKRLQLVYTEETSENESTTLSEETESIEKQTKKKQKWWKLWK"
     gene            complement(1734..2702)
                     /locus_tag="ACIZE9_003077"
     CDS             complement(1734..2702)
                     /locus_tag="ACIZE9_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HGC6094871.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEEQNRALELANRQTQHEKETTSLQERIKEQKRKLELL
                     QQLEELEKQQKNRENETDKQKLDNNSDIPLELRKDLLDNLQNLFKD"
     gene            complement(3861..4025)
                     /locus_tag="ACIZE9_003078"
     CDS             complement(3861..4025)
                     /locus_tag="ACIZE9_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094872.1"
                     /translation="MKLTKLTISLVIIAGIILYFVLPANQFFLYFGIPTILIVNGVRI
                     FEQRKKCSST"
     gene            complement(4044..>4408)
                     /locus_tag="ACIZE9_003079"
     CDS             complement(4044..>4408)
                     /locus_tag="ACIZE9_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGC6094873.1"
                     /translation="FSVLFLINILNTSFSEGINPNEVNGSLLLFFLNAATYGAFLEEG
                     IFRFCMIDPQANKKQQYISILISSFLFSIVHGGGLSIFFIGIILSFVYIQTKNIWYSI
                     VAHGFYNTIGILIYLISI"
BASE COUNT         1359 a          734 c          703 g         1612 t
ORIGIN      
        1 aaaaaaaact atatttaaag agttttttta gatttacttc tttgaattca cgaatgaagg
       61 tagaatgaaa tagtataatt attagcacta aaaaaaatat atcactatgt tcaaataaaa
      121 aatatatatt tgacggtact cctaatgatg ggatagcaaa ggtcaaaacc aagtaagcaa
      181 tactaattat ccattttatt gtcattaggc aggaatataa tcaatatatt gtgtatttgc
      241 tgtagaagtt tgagtacgaa tatatttatt atctacctta cgataaactc tgtaggttac
      301 agttattctt gcattttgac gatatttttt aaattttcca cttgcagaag tgtttctggc
      361 tatttcgatt ttcatcccaa atacatttgc actgacagat aactttgtac ctcgactatg
      421 agtttctata cctaaataag tacggcttcc tttagcaatt gaccagcttt gaggtttaga
      481 ccaagtcctt gtttgaataa ctggttcgtc taacacatag tagtactcat catcagaata
      541 agtggctata tcagaaatgt tgttctcatt agcgaatacc gctccgctag gagtaatagc
      601 agaaccaaaa gttaaaatag aagtagataa taaaaaggtt ttaaataact gttttttcat
      661 caaaatcacc tcgaatataa gatacttaag aaaacgcttt ctttatataa ttagaataat
      721 caggaaattt aatgttgtca agagggttta ttttataaaa gctgttatat taaaggttag
      781 tagacataat gtcgactatg ccaagtagcc cttgtatcaa ccgatacaga ggctcacttt
      841 gtgattttgg attggtctag gtaaaaagct ctttttaagg cttgattttt cgcggttatc
      901 tatatctaat tctttgtgca tttttatctg tcatttttta aagacttgtt atttttgaga
      961 ggatttgata cgctttgttt gtatctcatt ttcatctaat aaatggttta tgttgctaaa
     1021 ctaggataat ctcattttgg gctgctcgtt agagcagtct ttttttatta tttatccgtt
     1081 tcttttacaa ataactcttc gttaggactg ttgtaataat ttggattcaa tttcaattca
     1141 ccatgtttat ttcctttatt gatcactgac aataacatcg gactgaagcc tagaattcct
     1201 agtaaaatag aaccaaatat gagctttttt cttgtcatga atgtttcctc cagttatttc
     1261 catagtttcc accatttttg cttcttcttt gtttgttttt ctatcgattc tgtttcttca
     1321 gaaagagtag ttgattcatt ttctgaagtt tcttccgtat aaactaattg taaccgtttt
     1381 tgtagtttgt cgatttgttg atttgcctgc aaggtgagtt gttgttgctg gtcgagtaat
     1441 ttttgttgta tttctatgac cccttgtaaa tgatcaattt gtttgttttt ttcttttaat
     1501 tctgcaatta aaatactatc aactaaactg tcaacttcag tatcaacttc atttatttgg
     1561 ttgatactat tttttataaa ctcttgagct tttgctgata ttacgtattt tccacctatc
     1621 aacttaggtg tcaacttggt tggcagttta tcaaaatact ttctaatggc ttgtttgctg
     1681 acacctagtt cttctgcaaa ttcttttatt gatttatctg tcatgaatac tccttagtct
     1741 ttaaataagt tttgaagatt atcaagtaag tcttttctta gttctagagg aatatcggaa
     1801 ttgttgtcta acttttgttt atccgtttcg ttttctctat ttttttgttg tttttctaac
     1861 tcttctaact gttgtaaaag ttctaatttt cgcttttgtt ccttaattct ttcttgtaat
     1921 gaagtagttt ctttttcgtg ttgagtttgt cgattagcta gttctaaagc ccgattttgt
     1981 tcttctttgg ttggtgcatg tttgttaaag tcgtctgctt ttttgatttc tggtttaaat
     2041 gtgaattggt agccaatgac aggcttccca cggccttttc cgtatttctt tttgattgtt
     2101 aaacctttaa agattgcggt tagttcttgt cgtattggat tgaacacacg ttgatcgatc
     2161 gtaccttggt tgtaactttt aggaatatca agtaattcat gaaagtcttc ttttgaaaaa
     2221 taagcgaaac ctttggttct gtattgtttt agtaatcgaa acattgtttt tgaataactg
     2281 ctttctaatt cattgaattg ttggagagaa tagcgcaccc attcttcaag attattaagt
     2341 aagggtaagg ctttttcatg aacttgtatt tcagcaaaag gaatatcagc ttttccgtcg
     2401 attttaaatt gattaaataa aacaaaacgt tcacgttgca aaccgtcagc acttcttcta
     2461 ccaaaacgta aatccattaa tttgtcatac gttgtttcta aatcatctat gaatcgaaca
     2521 tttgcagttg ctttataatt gcttaaatct tttaattgct cgaatgtaaa ttgtactttt
     2581 ttatcaccta catcacgcat tcttgatacg atagagaaga acaaattcat ttcgactggt
     2641 gtaaattttc gcaacggaat tgtatttaat tcatgatgat actttacgat ttcattagac
     2701 atatttaaaa tagctccttt cttactcgca caagagatac agacgttatg aaatacaaaa
     2761 tgtctgttta tctacatctt atattaacat cgtcgatgta ctaattcaat gtacaaacag
     2821 acaaaacgat gtagataaac agacaaaacg atgtagataa acagacaaaa cgatgtagat
     2881 aaacagacaa aacgatgtag ataaaagcgt cattcccttg ggagagtaag gatacagccg
     2941 acggtaaaga ggtttaaaaa gaggtttaaa aagagattat aaaagagggg gacaaaattt
     3001 cccgcctaaa aaaccacttc ttttttctcc aaacagattc gcgcattttt ctaaactggg
     3061 aatcttactc cctatagttg cttaaaaagg tgtgatcgct ctgctctcac attatactgc
     3121 gcagtcgcct ccggctcctt tgctaaaact gttcataagg aactctttga gaagctatga
     3181 gccttcgttt gagacgtttt aagacagtct tagtataaat cccttatctt gttcttaaag
     3241 cgccttacag gcggtcaggg caagccctaa caaccctaaa attgtctgaa ttccctctaa
     3301 aattcgattt aagcactctt aactctattc ttatatattt atatacttag acatttgaaa
     3361 cgccttaaaa cgcaaattag agcttgataa agatatttgc tcgtgtgcct agacttttaa
     3421 aaaagtcggc acacgccatg acaaagctga aataaactgt ttcagctttg tcatggcgga
     3481 ttcgctcact tgaaaaagtg ttcatttcgc tcgattatta gcatatattt tttcgctttt
     3541 ttgctagcca aattttgcat tagttcgctc ataagtccca ccctttcagt acgtccgagg
     3601 gacgtatcgt tcgtaatgtg agagtgccta taaggtcact ctctacaaaa ctcactaaaa
     3661 gggtttggca agctctatat ttgctagcca aatacctacg tatttggtgc aaataaccgc
     3721 ttgtcaaagg ggcgcaagct cccccttgaa tcccccctca aaacccacgc tccacaatac
     3781 aaaaaaggct agcaaatgct agccactttt tgtaaagttt cgcttgtttc accttcggtg
     3841 aaattgttgc tttgcaacga tcaggtagag ctacattttt ttcgttgttc aaatattctt
     3901 acgccattta ctattaaaat cgtaggtatt ccaaagtaaa gaaaaaattg attagcaggt
     3961 aatacaaaat ataaaataat accagcaata attaccaaac ttatagtaag ttttgttaat
     4021 ttcataaagt atgccacctt atcttatata gatatcaaat agattaatat gccgattgta
     4081 ttataaaatc catgagcaac tatggaatac catatatttt ttgtttgtat ataaacaaaa
     4141 cttaaaataa taccaataaa gaaaatactt aggcctcccc catgaacaat agaaaacaga
     4201 aaagaagaaa ttagtattga aatatattgt tgttttttgt ttgcttgagg atcaatcata
     4261 caaaatcgaa aaattccttc ttctaaaaaa gctccataag tagcagcatt taaaaagaat
     4321 aaaaggagag aaccatttac ttcattagga tttatacctt ctgaaaaaga tgtatttaga
     4381 atattgatta ggaataaaac agagaatg
//
LOCUS       DBBGSP010000129         4372 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000129 DBBGSP010000000
VERSION     DBBGSP010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.130"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(83..1051)
                     /locus_tag="ACIZE9_003080"
     CDS             complement(83..1051)
                     /locus_tag="ACIZE9_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC6094874.1"
                     /translation="MSKKRTIVNEWEKLTALSNRRLNVQTLVQTIKLNWSIDRITIVG
                     KLNQNIFYHTQHDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQHDENIAYIEISKW
                     QEGKGRIDFNPNKISRFLADSMKNFIHDLFLEPHFSRADVACDLIDVPDEFITQYRII
                     DPVSFKLIYGRSGKLETVYWGSRASERQIRLYNKKIEQEMKRKVVPSEINTWWRLEMQ
                     LRRGKATEWYAMVKESLDSFVSPHFLPTDIKPTDKVMIDGLLANHSNWAILSRNSKYK
                     YRNLLKRESQNDELTNHLRETFEESADDLKKELDTWLQGLDVTEEE"
     gene            complement(1496..2902)
                     /locus_tag="ACIZE9_003081"
     CDS             complement(1496..2902)
                     /locus_tag="ACIZE9_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HGC6094875.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDRQKTNDWHKHIDFTKSDEN
                     IYLEQTNLADKYEELFGEVVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     ILDDFQTNRADGSSTGISKQQAEQNRVIANKILVQYYKEFQERNPNLAVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALVQQGIHADKDNGRVLFNNFRNQEVDSIE
                     RLMNDYGWKRDIVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYIYRQREE
                     NERDKALMASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSENEIEW"
     gene            complement(3124..3486)
                     /locus_tag="ACIZE9_003082"
     CDS             complement(3124..3486)
                     /locus_tag="ACIZE9_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094876.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKTVDNEWLADEKSAPSERDYPDESDDLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(3490..3798)
                     /locus_tag="ACIZE9_003083"
     CDS             complement(3490..3798)
                     /locus_tag="ACIZE9_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094877.1"
                     /translation="MDKIDLREETVDRIELMYERLADYLNLPDEDNYSEMLERIMDVL
                     NSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQISVINSKEKEM
                     "
     gene            complement(3807..4226)
                     /locus_tag="ACIZE9_003084"
     CDS             complement(3807..4226)
                     /locus_tag="ACIZE9_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094878.1"
                     /translation="MTDLPEKMTIKNLADELGISKNTVRNQLVNAGYDLARYKDNGVI
                     MLDKELIGVVRSIYRSKGGQLTGDLPVNDAGNDFPLEKENEFLREQLAEKDRHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
BASE COUNT         1241 a          979 c          604 g         1548 t
ORIGIN      
        1 aaaaaaacaa cgacaacgtt atcacctgtt aaattcacca accaattttt cttaccaaaa
       61 tgcttttgtt tttctgccat tactattcct cctctgtcac atcaagtccc tgtaaccaag
      121 tatccaattc tttttttaaa tcatctgctg attcttcaaa tgtttctcgt aaatgattcg
      181 tcaactcatc attttgactt tctcgcttta ataaatttcg atatttatat ttcgagtttc
      241 ttgacaaaat cgcccaatta gaatgattag ctaacaatcc atcaatcata actttatccg
      301 taggttttat atcagttggt aaaaaatgtg gactcacaaa gctatccaaa ctttctttca
      361 ccatagcata ccattccgta gctttaccac gtcttaactg catttctaac cgccaccaag
      421 tattaatttc tgaaggcacc acctttcttt tcatttcttg ctctattttt ttattgtaca
      481 aacgaatttg ccgctcgctt gcccgactac cccaatacac cgtttccagt tttcctgagc
      541 gtccataaat taatttaaat gaaactggat caataattcg atattgcgtg ataaactcat
      601 caggcacatc aataagatcg caggcaacat ccgctcgtga aaaatggggc tctaaaaata
      661 aatcatgaat aaaatttttc atggaatccg ctaaaaatcg actgatttta ttaggattaa
      721 aatcaatccg cccttttcct tcttgccatt tagaaatttc aatataggca atattttcgt
      781 catgttggtc taatagctgc caaccattat ttccaaccgc ttttaaatag ccattgcctt
      841 catttacccg cataagctgt tcaaaatcta atattaatac atcatgttga gtatgataaa
      901 aaatattttg attcaacttt ccaacaatgg taattcggtc aatcgaccaa tttaatttta
      961 tagtttgtac caaagtttga acatttaacc gcctgttaga cagggctgtt aatttttccc
     1021 actcattcac gattgttctt tttttactca tattcagttc ctcctcaaag aaaaaagaga
     1081 tttttggaaa gaatttccag agttcacgta actctaaaaa ttcataacca tcaatctcta
     1141 gtcttgaaga aacctaaaaa tattcgtata atgaatttga gttacggaac tagtgtggtt
     1201 agtttccgta aaggtcgaga acgttggtag cgttgctcga cttatttttt tgctcttttt
     1261 ccagttcatt tgtttgctaa ctcaataata gcacttctct ttagctatgc aaataccaaa
     1321 aaaataaaac cgcacccttt gaaaagggcg cccccaaact tcgctaacgc taagttggcc
     1381 aaaaaatgga cttgccattt tttagcaaat gtcagcttca ggggctagtg gtttagccgt
     1441 caactcctta tcctcggcac aaaccgcctc cggtaccgtt gactgcacat cgtggctacc
     1501 actcaatctc attctcagaa cgctctaatt tatgctgtga gacgttttga cgataaaata
     1561 aggttttctc ctgctctaat acttctaatt cctcagaaag ccccatatcc ttttctgcaa
     1621 gaccaaaacg gatagacaaa cgagtgatcg atttttgaaa tgcgtttttt aatcgctcta
     1681 aacgctggcg taaagagcga ttttcttctt tcagcttttt attttccact tgtaaatctg
     1741 ctaattgttt tctaccagac aaatgacgct cttcttccaa tgtagctaca tactcattta
     1801 attctgtatt ttgctcaagc atctgtaaat attgctcact catgttatca gcatttctct
     1861 tggcatttgt tgctctcgta gctcgttgat acaaatcaac aaaatcattc ccagataaat
     1921 gatacgaacc atcaggaagc ctcttgaaac tttctaaagg aaccatatct ttttggaaaa
     1981 tgaccgccat ctcttttttt acattcagca tatttttctt ctcttcttca atcttcgctc
     2041 tctcagaagc catcagagcc ttatcacgct cgttttcttc tctttgccta taaatatacc
     2101 tcaactcatc agaaacgctc tcacgctctt ttacagccgt ttggcgcaat tcagaaattt
     2161 cactcatgat ttctttgtat tcgtgaatat ctttaatttt gttggtaccg acaatatccc
     2221 ttttccaacc gtaatcattc attaatcgtt ctatagagtc aacttcttga tttctaaaat
     2281 tattgaaaag cactcgacca ttatctttat cagcgtgtat cccttgttga accagtgctt
     2341 tattaaagct cggctgcttt tgaacacccc gtttataacc ttcagcaacc ggcacaatat
     2401 tcaagtgcag gtgcggactt atttcgtcat tatgaataac agcattataa acagccaaat
     2461 tagggtttct ctcttgaaac tccttgtaat actgaaccaa aattttattg gcaatcactc
     2521 gattttgttc agcttgttgt ttcgatatgc cagtagaaga accatctgct cgatttgtct
     2581 ggaaatcatc taaaatgcct atttgcacaa taaattctcg ttgaggttcc aactttttat
     2641 ccttgcgcac tttcgctaaa tagtcctcga tttttctatc ggctcttttt tgtttcgcat
     2701 tatatttttc taccacttcg ccaaacaatt cctcatattt atctgctaga ttcgtctgct
     2761 ctaaataaat attttcatcc gatttcgtga agtcaatgtg cttatgccaa tcattggttt
     2821 tctggcgatc agttaactca cgattattat gagaaatact tgtattcttc gttccttttt
     2881 taaatgaaat actaaacccc aagttaaaac cctccttcgc gctgtcgcta ataaaaagat
     2941 tgtaaacctt tctgttactc tttgtcaaag agtaacattt tcctaattgt gacatggatg
     3001 tcacaattcc aaacgctctc cgagggtttt cgctgtcaca agtgacaacg aaaaaaggag
     3061 ccgaaagcgt atcacgctat caactccttt tatgctttat tttgcttcac gcaaaataat
     3121 cgcttatcgt aaattcacgt cattaaatat tgacgtaaat ttactctcac tcatctgact
     3181 tttcttattc ggtatcactc cgaataagtc gtcagattca tcgggataat ctcgttcgct
     3241 tggcgctgat ttttcatcag caagccactc attatccact gttttttcgt gttgctgatc
     3301 gtcagaaatt gacgataacc accgctcaaa atcagcaaaa gtttcaaacc caaaacgctt
     3361 gcgaagagcc ttgcccattg cagcattttc tttctcaatc aagcgttttt tctgttggcg
     3421 aagtttcgct tgttcttttt ttaatttttc ttcttgcgct ttaatatctg ctaaagtcat
     3481 tcccataaac tacatctcct tttctttgga attaataacg gaaatttggt ttaactgcat
     3541 aacatgactc attaatttca accaaaattc tttttctgat tcatcagttg tttgcgctaa
     3601 atgcttatga acaaattcat tagtcaaaac tgaagatttt gctagatcag cattgataac
     3661 cgagttgaga acatccataa ttcgttcaag catttcacta taattatctt catccggcaa
     3721 attcaaataa tcagctaacc gttcatacat caattcaatt ctatcgactg tttcttctct
     3781 caaatcaatt ttatccatgt cacacctcac ttccagaatt gccaccattt tcgatttttt
     3841 aattcttgat tttctagtaa caactgatcg tttttttgtt gctgaagcaa agtcaatttt
     3901 tgttggtcac gaatcatttc cgttaattca gaaatatgcc tatctttttc cgctaattgt
     3961 tcacgcaaaa attcattttc tttttctaac gggaaatcat tgcctgcatc attgaccggt
     4021 aaatcaccag tcaattgacc accttttgac cgataaattg accgcacaac accaatcaat
     4081 tccttgtcta acatgataac cccattatct ttataccgag caaggtcata acctgcattg
     4141 accagttgat tgcgcactgt atttttagat atacccaact catcagcaag gttttttatg
     4201 gtcatttttt ctggcaaatc agtcattatc ttctccgtta ctttcagcta ccccataaac
     4261 atatttaaca gcatgcttag ggataatgat tggggaatca attttattat ttttcaaaat
     4321 caactcatac tgcgttacat caagtaactt accggacatt tttttgctat cc
//
LOCUS       DBBGSP010000130         4335 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000130 DBBGSP010000000
VERSION     DBBGSP010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.131"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            127..579
                     /locus_tag="ACIZE9_003085"
     CDS             127..579
                     /locus_tag="ACIZE9_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094879.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="ACIZE9_003086"
     CDS             593..1282
                     /locus_tag="ACIZE9_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094880.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="ACIZE9_003087"
     CDS             1407..3758
                     /locus_tag="ACIZE9_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HGC6094881.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3838..4233
                     /locus_tag="ACIZE9_003088"
     CDS             3838..4233
                     /locus_tag="ACIZE9_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094882.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
BASE COUNT         1526 a          548 c          867 g         1394 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgtttact atttaaacag
     3781 tgtccttttc ctttttaaat atatacgata aaataagtat atgaattgta aaaggacatg
     3841 atgattatgg aagaaataga atggaataat ctgactcaaa ataataaaaa taattctgga
     3901 tgtggaatta tctttatgtt tgttatagtt ttgggaatag tagtactttt aataactgtc
     3961 aagatagtag attactttgc gaatactcct gaagaacaaa tacagagaaa acttcctgag
     4021 tttgaaagag taccacctta tgatccaaga gataattcat ttcaagtaaa aaaattaaaa
     4081 gagtctccaa atgaaatgtg gtttgaagtt acagttgaat caagcgactt caaagaaaaa
     4141 aagaaagaat acaattatat tgtaaaggca aaagtatcaa aaagatttat ttttaaccct
     4201 aaattagaaa tatatagtgt tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa
     4261 agaagtcaaa ttctgatgtg aaaaataaaa tataccatgg aagacataaa agaaaaactg
     4321 gataactagt ttatt
//
LOCUS       DBBGSP010000131         4241 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000131 DBBGSP010000000
VERSION     DBBGSP010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.132"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..618
                     /locus_tag="ACIZE9_003089"
     CDS             <1..618
                     /locus_tag="ACIZE9_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HGC6094883.1"
                     /translation="PTTVDGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNK
                     FKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHV
                     IGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHT
                     GVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISSIVIPPK"
     gene            631..1539
                     /locus_tag="ACIZE9_003090"
     CDS             631..1539
                     /locus_tag="ACIZE9_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HGC6094884.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            1539..2156
                     /locus_tag="ACIZE9_003091"
     CDS             1539..2156
                     /locus_tag="ACIZE9_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094885.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            2160..2609
                     /locus_tag="ACIZE9_003092"
     CDS             2160..2609
                     /locus_tag="ACIZE9_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094886.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            2609..3103
                     /locus_tag="ACIZE9_003093"
     CDS             2609..3103
                     /locus_tag="ACIZE9_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094887.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            3117..3548
                     /locus_tag="ACIZE9_003094"
     CDS             3117..3548
                     /locus_tag="ACIZE9_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094888.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            3550..3687
                     /locus_tag="ACIZE9_003095"
     CDS             3550..3687
                     /locus_tag="ACIZE9_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HGC6094889.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            3724..4017
                     /locus_tag="ACIZE9_003096"
     CDS             3724..4017
                     /locus_tag="ACIZE9_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094890.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            4014..4238
                     /locus_tag="ACIZE9_003097"
     CDS             4014..4238
                     /locus_tag="ACIZE9_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HGC6094891.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
BASE COUNT         1514 a          611 c          932 g         1184 t
ORIGIN      
        1 cctacgacgg ttgatggatt taaggcctgt actgatccaa gacaagcagc atatgctttt
       61 gaacgaaact atgaacgtcc ggcagcgaca catcctgaac gtcaagatta tgcagttaac
      121 tggtataaca aatttaaaga tttaaaacca ggaggagcta ctggagaagc aggactaaaa
      181 catttagagt ctttgattgg acaacgaatt ggcaatggtc agtgttatgg cttgtctgca
      241 gaatattcag gatatctggg tggttgtggc atgggtgctg gaacaaaata tggtttaact
      301 catgtgatag gaaatacttc tgcagcatct gatattggta ttgcctatga ttggtctgct
      361 gttggttgga aagtgattca aaaccctaga tatgatcaat tagtagttgg tgcaattatt
      421 aattgggcaa gaggtggaca agtgggttca tggtttgcag atggaactta tggacatact
      481 ggcgttatcc gaggcttagc taatggtcgt atgcaaactt atgaacaaaa cacagagtta
      541 ggtatgattt gtggaaagtt agatcgacag tattatagtg caagtgcaat ttcttccatt
      601 gtcataccac caaaataggg aggtgattta atggcaaagt ggaatgtcat attaagtaca
      661 acagaaccct ataattacgt ggggatgatt caagttcgac aaggcaataa aaacactgaa
      721 gttatggaag ctacaattgt cgaaaatggt cttccatatg atttatcaga atgtaaggta
      781 tattttgaat cagttgttgg cggaaaatat ccagtccaat tagaaacaaa aattgtggat
      841 gctaaaaaag ggaaaatcaa atatattttt gataaatatt ccatgcagtg tttgcatcga
      901 caaacagcca atttcattat atttaaagga gaagacttga ttggaacaac tcaagacttc
      961 tcttattttg tcatcaatgc tgtttcaaaa acagaaggag aaatgggttc ttattggcaa
     1021 tcaattgaag atttaattgc tgatatgaca gattttatta atgaaaataa aggcgatttt
     1081 acggactgga tgaatgaaag gaaagaagaa tttgatcgct ggagagagga acaggagaat
     1141 agtttccaag attggagaga aggacaagaa tcagattact tgtcatggtt tgaatcaatc
     1201 aaggatattt tgaagtctat cgatccaggt ggagtaatgt tagccgaatt aatggatgca
     1261 cgtgtagatc ttcaaggtgt acgccatgaa tcgatttctg aacgtttcct atccgatcta
     1321 aattatttgt atcaaaaaat gaaagcagca cttttcacga ttgaatacgg tgaaattgaa
     1381 gtgactgata ttcttcaaga cgatctcttt tcagataatc acgaagtcga aaaaattgaa
     1441 acagtagaat ttccaattga agaaggagct ttgattattg caactgttga tgatccaaaa
     1501 cagaatgttt tcactcttga gaaagttggg gtgatttgat ggttaaagta aagagaatga
     1561 tggaaactga tgaatctggt gttaaacgtc aatttatgcc aattacacat gtctctgcag
     1621 ttttaggctt agaaaaaatg atatcaggac aatcaaaagt tctttcggtt aatggtaaat
     1681 atggtgcagt cattttaacg aaagctgatt taggattaga gaatgcaatt actgaactac
     1741 cttatgcaag cgagacaagc gatggtattc ttactgctga aatgtttcaa aagatcgtaa
     1801 atggagaagg tggaacatat attttgccga ttgctactcc tgaacaatta ggaggtataa
     1861 aagttgggga actcttagaa gttactgaag aaggtgtttt atctgcaact aagcaaacag
     1921 acttcaattt ctctgaagaa ttaaaaggaa aattagaatc tctaaaaata ttaaaagcag
     1981 gtgcaaatat atcaattgca gaagatggaa caattagttc tacaggtggt agtgggactg
     2041 gtggtgttaa tcagtcatat gtagatcaaa aattccaaga agctgtaaat caagcagaaa
     2101 attacacaaa cgaaagaatt ccaaatttta cttttgaaaa aattggggag gtatagagaa
     2161 tgacagatat cgtaaaaata aaacaaagca atgtacaggt ttatccacaa actcattgga
     2221 atgctataga aggcaaacca acaacggtga agggagataa aggcgatcct ggccaagcag
     2281 caacaattac cataggaacc gtttctagtg gttcaaccgc ttctgttacg aatgtaggaa
     2341 catcatctgc agctagattt aattttgttt taccaaaggg agataaaggt gatcctggaa
     2401 taaatgccac aactacagct gtagctacaa ctacagcaaa tgggttgatg tcgtccacag
     2461 ataaaactaa gttggatgga attgcagctg gagcacagaa aaatccaggt aatgctacaa
     2521 ctacgacagc aggtttaatg tcagcaaccg ataaagtgaa acttgatgga ttagcgaata
     2581 ttacatttga gaaagtgggg acggtttaat ggctgatatt gttcaattaa aagaagacgg
     2641 agttgctaaa tacttaaaaa cgcatgtaga agctattgat ggtaaagaag cattggtgca
     2701 gacagatgga gaccaagcca ttgcaggaca taagaatttt tcaggttctg taacaatcaa
     2761 taataaacgt gttttgacga ctgatgataa cagatatgaa gtggtaaatc tggttgtcac
     2821 taacggtaat acagggacag caaagcttta tcgtgaagga aaaacagttt ctatatattt
     2881 tgtggcttta aacggaaaaa gtagtggcgg gaatgattcg gttattttaa ctgttccaga
     2941 aggctatcgg acaccaatta gttttgaaca actggttggg tcaatagacc gttctacttt
     3001 gaacagtgct caactatcta ttggcgcaga cggagccatt aaatggagaa gaaattcaag
     3061 ttatggatca gcttattcat ttgttatcac ttattcaatt taagggagga aatctaatga
     3121 aagtagttta caaatcaatc aagccttacg gattcgagca aatcattttg aacaatcaag
     3181 aaaatatccc tgaaaactgt acagagatta aaccaccagt tcctaactgg agaccaagat
     3241 ttgattttga taaaaaacag tgggttgagt tagctactga agaagagaaa aaagggaatg
     3301 ctgttgatag cgtagatgaa ttggctaata ttaaggcatt atacgaaacg ctgaaggcag
     3361 aaaatgatga attgaaacag ctaaattcta aagcaatgct aaacaatgta gcaatcaagc
     3421 aagaaaatgt cttattgaaa gaaaagtcag aaagtttagc gcagttgaat tcaaaaacga
     3481 tgcttgcttc tgtacaaaat accaaggaaa tcgaagaaat caaaaaacaa ttacaaggtg
     3541 ggaagtaaca tgtattcata tgaagatatc aaactaatgt atgactgggg ctgtttcact
     3601 aacgaacaag taatggtttt cgttccatta tgcattacag acgaagaagc agataaaatc
     3661 attaataaag ataagagcgc atcttaattg atgcgttttt atttaaggta aaggagttgt
     3721 cacatgatta atttagggga atggggaatg atagcaggat caataaccgc tatcgtttct
     3781 ttgattttat tagtaattag accgattgct gcatctttct cgaaaattac tgagactctt
     3841 tcaaaagtaa gccacaattt agatttgctg actaaagatt tagaatcgag caaatcagat
     3901 cgattgatga ttcatgaaga actaaagaaa cacgatgaaa gattagatac acatacagaa
     3961 aaattggtgg aacacacgca acaaatcaaa actttgttta gggagagaag aaaatgaata
     4021 ataaaacgtt cgaagtacta aaatggttcg cactggtaat tattcccgca ctagctactt
     4081 tcgtggggtt agttggtaaa gcgctcaatt ggcagtacac agatatctgt gttgtcatca
     4141 ttactggttt tggcgcgttt ttagggagtg tgttgggtgt atcaaatcga acctacaaaa
     4201 tgttctcggc tgaaagcgaa gaaggaggaa acaaatgaaa a
//
LOCUS       DBBGSP010000132         4067 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000132 DBBGSP010000000
VERSION     DBBGSP010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.134"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            86..1435
                     /locus_tag="ACIZE9_003098"
     CDS             86..1435
                     /locus_tag="ACIZE9_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC6094892.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="ACIZE9_003099"
     CDS             complement(1563..2153)
                     /locus_tag="ACIZE9_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HGC6094893.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2300..3652
                     /gene="brnQ"
                     /locus_tag="ACIZE9_003100"
     CDS             2300..3652
                     /gene="brnQ"
                     /locus_tag="ACIZE9_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGC6094894.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1173 a          744 c          789 g         1361 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta cttttaaaaa
     2281 aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc tttttatagg
     2341 ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg ttcatttggg
     2401 tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta ccggtatcgg
     2461 tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg tatatgaatt
     2521 agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt acttagttat
     2581 cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg gtttagcacc
     2641 atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg tattttttgt
     2701 gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg gaaagttcct
     2761 gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt tgaatccact
     2821 aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt ttttcacagg
     2881 gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg ggatcatcat
     2941 tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta aagacacgat
     3001 caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc tcgcttattt
     3061 aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca cgctggctca
     3121 gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta tcgttatatt
     3181 agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat tcacagattt
     3241 gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc cttgtttagc
     3301 ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga tgttcatcta
     3361 tccattagca atgacactga ttttactagt gttagttggt cctttgttta agcagcgtac
     3421 ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg atgggttgaa
     3481 cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat atgttgcgga
     3541 aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag ttatcggttt
     3601 tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt gataaaagag
     3661 gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa ttttgaaaaa tggcttctca
     3721 catttttgca taaatttgac ttaataccga gaaactgact tttgaacacc gtttattgag
     3781 aggtcgtgaa aaagccgctt agtttcaagt attaagaaat attttgtgaa aatggcttct
     3841 cacatttttg cataaatttg acttaatacc gagaaactgg cttttgaaca ccgtttattg
     3901 agcgtctata aactgacctg agtattagag aaacaaaacg gcaaagtagc tccatatact
     3961 ttgccgtttt gttttgaact aataccgaag agaagctgat caaacaacat ttcttttata
     4021 atatagattt tagacatata tatgatataa aaatagtttt cgcaaaa
//
LOCUS       DBBGSP010000133         3876 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000133 DBBGSP010000000
VERSION     DBBGSP010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.135"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(716..3865)
                     /locus_tag="ACIZE9_003101"
     CDS             complement(716..3865)
                     /locus_tag="ACIZE9_003101"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HGC6094895.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1076 a          803 c          635 g         1362 t
ORIGIN      
        1 actaatacag gtagtcctct tttttgttat tttgatattc taaatcattt tttattggat
       61 tattcccttg ttcgatatag acccaaattg atctatcaat aattatcaaa ctgagtcata
      121 tagagacaaa aatttcaaaa atgacctgtt aaatggtcat cgaatatcat ttaaaatcaa
      181 tacgacggag tcagacacgg agtcaaaaca agcccgctga gagtaaaaaa tatatacagt
      241 cccataggta aagtgccaca ggactgtata tttttttatt tgagattacc tgaaatgatt
      301 ccatttactt tttatctcat tttttcctac tagttagtat caaatactct cctattttct
      361 caataaacta ttttgggtta catggtatct gaaacagcta aaaccttgtc attacagcaa
      421 aaaatcactt tatctccgtt tcatttcaga tacatttcac ttaagcggat tccaaaaaaa
      481 caaaagaaaa aggaacccct agttagccta tgctttttat tggttcctct caaaacacgg
      541 tcatataaca acggggtggg gtaaatgaat gaaaaaggtg gaggaaacat tattcaatag
      601 ctgtcttaaa tacttcgtta taaaatgtga acaaataaaa gacatctatc cctattttct
      661 acacttccac tttactacca tctttgaatc gtacaatttt cttaactctt ctcgtttacc
      721 tcaattcatt ttcaagtgga atcagctcat catctaacat tttacgccat gctcgcttca
      781 tttcttgtgg gtatttaaat ggcttcgctt ctggatggtt ggctttatat ccttcgtaat
      841 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
      901 gattagaagc atgtaattct ttctcagaaa caaaccactc attggaaaag acatgaatca
      961 aatcatcact cgcttgtgta aaatagcgac gtttaatgac aaagatatct tcattactat
     1021 ctaaagtccc cacatcaaac gcatttaaaa tttgtcggta aacttctttg actccttctg
     1081 ttttattcaa tttagccaaa gctttttcaa tttcttctcg tgcatctgaa ctattcgccg
     1141 cataagttcc tagtaattga tcaatataag tagaatcaat atcatacaac ttcgtggtat
     1201 tttcactata aaattcgatc gtggaaaaat cttctccctc tttttctggt tcttcctcta
     1261 ttaatgaacc cttcacggtc tcgtacacgc caatttgttc ttccaaaagt tgaatttgat
     1321 tgttcaaggt tgaagatttc accatgtcat cattgtaatc gtcataagtc actaacgatt
     1381 cataagcacg attcaattct tggaatgctt tgacgtactc gatacggatt tcaagtggcg
     1441 tatgttcatc aatggattcc atggatgaaa cctcttttaa cttaccatat gcttgcttga
     1501 atcttttttt ggattcctga taacttggat aaatcaaacc cgattcttct tttgcttctg
     1561 aatacagttt tgtcgcatcc tcgacattct tctccattgt ggctggcttt cggaaagtaa
     1621 caattagtcc ttttgttttt tctggatacg tacggttcgt acgtgaaaaa gcttggatca
     1681 atcctgcata ctctagatta cgatccacaa atagggtttg aatcgtaggt gcgtcaaaac
     1741 ctgtcaatag acgatccact acgatcacta aatcaatttg tttcccaaat tgtttgaatt
     1801 ccgctctttt tcgtgccaaa cgattattga tgtctccgtt ataacgctca atgtctgcta
     1861 atgaccagga agtatcataa tactgattat attcctcaat aattttttgc atttcttctt
     1921 gttggacact tgaatctcgg ctgttttctt ctaatgaata ggtaatagcg attcgtggaa
     1981 aatcaggatc ctccatcgtt cttccttcac gaatgggctg attaggaaac tcttttgtta
     2041 accagtcagg ttctttcgtc atttctttga tcgctcgata atactttttg gccatgtcaa
     2101 tggaactcgt ggttaagatc gcagacttcg ttggacggcc atttcgaaaa tcaaattttg
     2161 tataggcatt gtctggacgg aacattttat gaatgacttt ttggatatgt tcatctgctt
     2221 caaaaacagt agggtccaaa taactttctt ttttgacagg ctccatttga tcaatcatac
     2281 gattgatctg ttccggtgaa tactctgcat atgtttctac ttcttttaat ttccgataga
     2341 ttttattctc taatgaagtc ggctccacgg tgttttcatg ctctacttga aatcctaaaa
     2401 ccgagccatc ttctaatgca ttcttgatgg tataggtatg caagacctct ccatactgat
     2461 catgggtcgt acgtgccaat tgccctttgg cttgtttccg attctcaggg aaaatcggtg
     2521 tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt tttgatttct tccatatttt
     2581 cagcacttaa cgctcgatga cactcatcta ctacaaacac gatatgttgc cccattaatt
     2641 tttggaagcg attggttcct tttttctctt cttgtttttt tgcatatttc aacgccgcat
     2701 ctagcttttg acgggttgta ataatcacaa catttgcatt ggcatctgcc aacagagttt
     2761 cacttaactc tttggcactt cctgttccca cgatcaagct attcgctttg gcgttcccgg
     2821 aagaaatccc agtattaaat tccgaagcaa atttcgtaaa ctctgtggtg gtttgattat
     2881 ctaaatcttt gcggtccact aacatgatcg tccgatcgat ccccgatttt cgtgctaaaa
     2941 gcttagtaga tacaaaacta gtcaacgttt ttcctgaacc agtcgcatgc cacacatatc
     3001 ctgattgatg tttatttgca gcaataaaca aggcttgaat cgcatgtact tgataaggat
     3061 gtaacaccat gaggatttta ttgtcttgat cttcactgac aatcgtataa tccgcaatca
     3121 agcgatgagc atccgggata tttagcactt gtttgcaaaa ctcatataag ttttctacct
     3181 ttttattatc tttcgttcgc caactaaata aaaacttagg atgcaaatcc tttggtaagg
     3241 catttgcaaa ataccgagtg gtttgttcat tggaaaccac aaacaactgt aaggtcgaaa
     3301 agatattgtt ccgaaacata ccttcttctg catatttttt gatttggtta aacgcctgat
     3361 aaaaactatc ttttgcggtt acttgtttca gctcgatttg gacaatcggt aatccattga
     3421 tcagtaaggt gacgtcaaaa cgtcgatccc gtgcttctat gttacttcca cgttttgcaa
     3481 tttgatggac cacttcatag gtagagattc ctccaccaat gtcttgatta gaataaagaa
     3541 tgagcgagac agaacccagt tgcggatctt cccgttcaat cgtgatccga gccattccat
     3601 tttcaccttt taaccatttc gcagcatcaa agggggtttt cgttcgtagt aacaattctg
     3661 ttttgatcgt ttcaaattct ttatcggtca aaggaaaatc attcagttct gcttgattat
     3721 ttgagatgat tttttggcgt aaattgaccc aaagatcttc ttctgatttt agatcgggac
     3781 gatacgtcca ctgattatgc ccttccccca atacacggat caactgttct tcgacttccg
     3841 cttcctcacg gtgactaatt ttcatttatc ttccct
//
LOCUS       DBBGSP010000134         3718 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000134 DBBGSP010000000
VERSION     DBBGSP010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.136"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..353)
                     /locus_tag="ACIZE9_003102"
     CDS             complement(<1..353)
                     /locus_tag="ACIZE9_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094896.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRT"
     gene            complement(613..1161)
                     /locus_tag="ACIZE9_003103"
     CDS             complement(613..1161)
                     /locus_tag="ACIZE9_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094897.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1162..2019)
                     /locus_tag="ACIZE9_003104"
     CDS             complement(1162..2019)
                     /locus_tag="ACIZE9_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HGC6094898.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2305..2591)
                     /locus_tag="ACIZE9_003105"
                     /pseudo
     CDS             complement(2305..2591)
                     /locus_tag="ACIZE9_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2581..2910)
                     /locus_tag="ACIZE9_003106"
     CDS             complement(2581..2910)
                     /locus_tag="ACIZE9_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGC6094899.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2987..3259)
                     /locus_tag="ACIZE9_003107"
     CDS             complement(2987..3259)
                     /locus_tag="ACIZE9_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGC6094900.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3259..3522)
                     /locus_tag="ACIZE9_003108"
     CDS             complement(3259..3522)
                     /locus_tag="ACIZE9_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGC6094901.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT         1091 a          754 c          473 g         1400 t
ORIGIN      
        1 aatgttctta ctgcctcttc cacactaatt tcttcgttca atttcactaa taatacttga
       61 tctcgcttat tataatcgct ttcatttatc ctaagagtca aatctttttc caccataact
      121 tttacaccca ataaattttg cggtttattt ttctctgttg aaattctttg tgtagccttt
      181 aaactgacaa ttagctcatt gggtacatac tctatttgag agtcatctaa ttggctcata
      241 atcctttctt tttggttagt atctgcagtt acttgtttag tatgagccat gaacccaaac
      301 atactcaccc caacaaccaa tcctaaatat attttctttt taaacttttt catctacatc
      361 tcctcctaat agttttattt tagagttagc tctattactt atttactaac tcaacaacag
      421 attatcatac acttgttaat gaaatcacaa tatctcatta aaacacaccc taaaatcata
      481 accgttccta tgctcatttt ttggattttt taatcacgta accagaaaaa taaatcccct
      541 ctatttcacg caaatcaaag aagaactaag taactaccgt ttaaaggtag ttacttagtt
      601 cttctttgat tattatctaa ctttattatt cattccccac cctttgcgca gtgagtcttc
      661 ggtatcttgt tttatctgac tggtagttct tattatttct ccacgatcat ctaattctgg
      721 aacaattgga tatttttctc tgaacaagtc tagttctttc accacgtcat taaacaaatc
      781 ttgcttatct tcttgcgtaa gattctgttt aatatactca tctaaagctt ttctaagcaa
      841 ttcatctctt gtcatattag tctcatactt ttctactaaa actctggaag tcgcatttaa
      901 caaagtcgac agttttaaag gatgcttggt ggaataaacc ttatcaaact ttctgattgg
      961 tgcgccaact ttttttgttc ttcctctact ctgtctttca acattggagg aagtttttat
     1021 ttcttgaact tggtgcactt ctaattgctt attttcagat ggtgtaattg cttgctgctt
     1081 tttctttgct tctgcttctt tttttatttt ggcgagtcct ttgttgttcc caaaaatatc
     1141 aagtcctttg atgtcagcca attactccac ctccgcatac caattctcgt gttcttccaa
     1201 ttctttcaaa atactgataa ataattcgtg gcttttgcga tcccattgtt ttaagagacc
     1261 tttctttgtc ttctccatcg taatacctga tccgtcgtat cgttttaagc gcgcattttt
     1321 gagtacaaca tttttaatca aatgttcccc ataaatctct tgggcttgtt tatacatttc
     1381 ctgatctact gcgtcaccgc tttccaacat gaaaggaata acaccagcaa catataaatt
     1441 tgtatcaaat tctttcacaa aaaagtccat atactcaaga tattgcatcg catttctcat
     1501 cgattttact tgggtctgta agacgacgat tgcccaatcc gcaatgtaca tcgcggattt
     1561 actatataca gaaatagaag gtgggacatc taaatagatg acgtcaaact catcaaataa
     1621 tggttctagc ttttctttca tatatttgaa ttgggataat gaatcattat attggtcttt
     1681 gatccaatca tcatacattt caaaggacat gtctgctgga agtatataga ggttattgat
     1741 tactttatag acagcctctt taggtggaag attgtttatc aacacgtcag tcacagtatt
     1801 ttcgtaaaca atcggttcac cttctccgcc tccttcttcg ttagtgaagt tcatatgcgt
     1861 taagttcatc acatcagaag tatttccttg catatccaag tcaattatca aggttctttt
     1921 tccttcatta actgctgatt caaaccctaa catttgcgcg cacgtacttt tacctacgcc
     1981 acctttaaaa ttaccgatta catatttctt cgctaccacg ttcctacctc ttttctttta
     2041 gcaatattca tttgatacta ttataacata tttattttta gttactacca aaaaaaagat
     2101 atatatgtac taccttataa ttaataagta aaaggtagta cataaataag gaaaagctga
     2161 aatatattga tttatagctt tcctcaaagt aatgacgtta tttaatttat cgagaagcag
     2221 agaatactcg cgactttagt catgtagacg aatcagattt tcgataaaaa agaagccgtc
     2281 cttcttaaga acgacaacaa atcactagat taattttttc aactgttcat aaaagttttc
     2341 atgcgttcca cataacaata ctggaataac cttgttttct ataatctcgt aagctactct
     2401 atatgttgtg cccgcatatt tgaacccact agaccaaata cctgataaat ccccagtttt
     2461 ttgttcaccc ttatatggat caatcgcaat ttcatcataa attaaattca aaaatttttc
     2521 tttcaatggc ttctctttta gctttttaaa tacttaatga catgttttga aggaacgatt
     2581 tcataagcca atttctgttg ccaactcctc tttagtcatt actttagaat tagtaagtgt
     2641 atcttcagca atatctctaa aggaagaatg cattttgttt tttctattct taaattctac
     2701 aagaatctca tctttatcgt agccttctgc aattatatca gacaaaatat cttcgctaaa
     2761 atcataaaat tctttttgtg gttcaacaaa ttcataaaga ataccattct ctaccaactt
     2821 tgcttcaact tcgactccat taggaacatt aaaatcttta ggtactgtca acatgattga
     2881 attgccttgt tttcttgttt ttgtaatcat ttaaatccct catttctaac agtatgtaat
     2941 tacttagtaa atacattata ccacgagata atgtatttac aagtaattac tgtgactcgt
     3001 aatgcgtcct tgctgaataa atttcaacca cgtgttcatc ttcatctacc ttataaacaa
     3061 cccggtgttg tctattcaat cttctagaat acctaccttc atgtgtaggt tttaacttct
     3121 caaatgattg ggtagggaga tagggatctt cctttaaagt ctgaataacc ttctcaaatt
     3181 gaggtttcaa attagactgt ttgattttct ttaaatcagc tttagccgag tttttaatca
     3241 tcacagaata gttattcatt ataagttatc ccaatcaatt tcatcaacat tagtaaatcc
     3301 actatcatct ttttctcgct tacgaacaac acccaaagtg cctatttgct caagtaatag
     3361 cgtttctttg attgctttcc aatcatccaa accaataagc accgcattat tttcactgcg
     3421 ctcactaatg atttcaattt ccgtatgatt ctcatttaca tctttcaaca acttataaaa
     3481 atttttccgt gctgagctag gatttaagac tgtttttgcc atatctactc cccctctaat
     3541 ttatatctcc attctaacgt acttaattaa gtacgtaaat tcgattgttt tgtttaaatt
     3601 ggagtaccaa aacagcattg taaagtgtta tccgtttcct ttatacccgt ggtgctagtt
     3661 aattttttcc tagaggaaaa tgtctaaaca tgttggtaaa tcaacaaaaa aacgcata
//
LOCUS       DBBGSP010000135         3552 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000135 DBBGSP010000000
VERSION     DBBGSP010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.137"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            132..953
                     /gene="racE"
                     /locus_tag="ACIZE9_003109"
     CDS             132..953
                     /gene="racE"
                     /locus_tag="ACIZE9_003109"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGC6094902.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            956..2311
                     /gene="rph"
                     /locus_tag="ACIZE9_003110"
     CDS             956..2311
                     /gene="rph"
                     /locus_tag="ACIZE9_003110"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HGC6094903.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            2312..2830
                     /locus_tag="ACIZE9_003111"
     CDS             2312..2830
                     /locus_tag="ACIZE9_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC6094904.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            2937..3437
                     /gene="cbpB"
                     /locus_tag="ACIZE9_003112"
     CDS             2937..3437
                     /gene="cbpB"
                     /locus_tag="ACIZE9_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGC6094905.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
BASE COUNT         1214 a          599 c          805 g          934 t
ORIGIN      
        1 taaagtcaca accgcttttc ctctttccat tcgaaaaaaa gagatttcga ttgttttaag
       61 caagtaagag cacttgaaaa ttcacgctaa aaagtacaca atagggagga tagaatttat
      121 tgaaaaaaag gatgatacga ttgacagata atcgccctat cggatttatt gattcaggtg
      181 tcggcggctt gactgtagta aaagaagccc tgaaacaatt accgaatgaa aatattttat
      241 ttgtaggaga cacagcacgc tgcccatatg gccctagacc cgcggaacag gtaatccagt
      301 atacttggga aatgacggat tatctggtgg agcaaggaat caagatgctg gtgatcgcct
      361 gcaataccgc aactgcggtg gctttagaag aaatcaaagc tgctctttct attccagtca
      421 tcggtgtgat ccttcccggt actagagcgg cagtaaaaaa aacacaaaat aaacaagttg
      481 gcattatcgg tacgattggt acggtaaaaa gtcaagctta tgaaaaagca ctgaaagaga
      541 aagtaccaga attgactgtg acaagtcttg cttgtcccaa atttgtttca gttgtcgaaa
      601 gtaatgaata ccattcatcg gtggcgaaaa aaattgtggc agaaacatta gctcctttaa
      661 ccactaaaaa aatcgataca ttgattttgg gatgcaccca ttatccatta ttacgcccca
      721 tcattcaaaa tgtaatggga gaaaatgttc aactgatcga ttctggagca gaaacagtag
      781 gtgaagtatc tatgctgtta gattatttca atttgagcaa ttcaccgcaa aatggtcgga
      841 cattatgcca gttttataca actggctctg ccaaactttt cgaggaaata gctgaagact
      901 ggcttggaat cggacactta aatgtagaac atatcgaatt gggaggaaaa taaggatgcg
      961 tcatgacggg agaaaagccc aagagcttcg caaactggag cttcaaacaa atgttttcaa
     1021 atatccagaa ggatcggtag tgatccgttt tggtgataca acagttattt gttctgcaac
     1081 aatagaaaat tctgttcccc cttttttgag agaaacagga acaggatggg tgacagcaga
     1141 atatagtatg ctgcctcgag caacgagtac gagaaatcgt agagaaagca gcaaagggaa
     1201 actttctggt agaacaatgg aaatccagcg tcttattggt cgttccttgc gtgcagtagt
     1261 agacttggaa aaattaggag aacgtagtat catcgtagac tgcgatgtga tccaagcgga
     1321 tggcggtact agaacagcaa gtatcactgg ggcatttgtg gcattgaaat tagccattga
     1381 aaaactttta agagaaaaag aattgtcaga agatccaata aaagaacatc ttgctgcagt
     1441 tagcgtagga atcttaccag atgggacttg cgtcacagat ttggattacc aagaagattc
     1501 cgcagcactt gtagacatga atcttgtaat gacagaatct ggaaaattcg tggagattca
     1561 aggaactgga gaagaagcaa cgtttgatgg tgaacagttg aatgaaatgc tcttttttgg
     1621 aaaaaacgcg attgaagatt tgatcaaaga gcaaaaacat gctttgctaa cagagtttgc
     1681 tcaaaatgat gagcggatag aagaaacaaa aacaatcatc attgcgacaa gaaatccagg
     1741 aaaagcagaa gagtttcgaa atatgttcaa agaagcggga tatcatgtaa aaacattact
     1801 tgactatcct gaattgccag atgtggaaga aactggcagc acatttgaag aaaatgcccg
     1861 attaaaagca gaaacgattg cacaattgct tgatcagcca gtcttagcag atgattcagg
     1921 tttgaaagtg gatgctttag gcggtatgcc aggaatctat tctgcacgtt ttgcagggga
     1981 acaaaaaagt gatgcgggga ataacgccaa attattatat gaattgacag atgtgccgga
     2041 tgaaaaaaga acagcacaat tccattgtac gttagtattc gcggcaccca aaaaagacag
     2101 ccttgtagta gaagcggaat ggcccggtcg agtagcccgt ataccatctg gcgaaaatgg
     2161 ctttgggtat gatcctttat ttatcccaga aggtaagaaa caaacagcag cagaattatc
     2221 gagcgaagaa aaaaacaaga tcagtcatcg ggctcaagca atgaaaaaat tgagtgccga
     2281 gtggaaacaa tggctggaag gagagagata gatgcggtat ttagtagtaa gtgataatca
     2341 tggagacaga gatatcctcg ttgacttagt agatcgttat cgttctgaag tggatatctt
     2401 tttccattgt ggtgattcgg aattagaagc ttctgaccca ttatgggata cattccaagt
     2461 ggttcaaggt aattgtgatt atggaccagg attcgaacag aaaaaagtga tccaaactgg
     2521 tcaggataca gtattcatga ctcacggtca tttatcgaat gtccgatttg gtttgacaca
     2581 gttagcaatc gaagctcgag ctgcaactgc cgatatggtg ttttttggtc atacccatca
     2641 aataggctgt gagatggatc agaaaatcct gtttttgaat cctggtagca tttctcagcc
     2701 tagaggcccg atccaaatcc catcatatgc tcttatcgaa agtttagatg accaaatttc
     2761 tgttcaatac tataaccgtg cccatcaggc agttgaagag ttggcctttt ctttttcgag
     2821 agagcgctga ataaaaaaac tctaattttt aataaaaata agctttattt tatgaatttt
     2881 gcatccggtt tcggtaaaat agtagtgttg aatgaaatag aaatggaggc catcagatga
     2941 ttggacctat agtaagagaa atgctgctgg aaaatcagga aacgtttttg attcctgcag
     3001 aaaatgtggc aaatgttatg tatcatcatc cattgtccca tggtttactt gtgttatcga
     3061 aggtcggtta ttccaaaatt cctgtattag gaaaagatga tcactttgta ggactagtaa
     3121 gtttatcaga tgtggtcaat aaaatgattg acttgcaaac aatcagcatg gacccgttag
     3181 aaggactaac ggttgctgat gtgacagaaa cagatgttcc gacaattgat gaaaattggg
     3241 aactagaaga agtactccat ttgttagtcg attcgccttt tttaccggtt gtcacagaag
     3301 atcggatttt caaaggaatc attacaagaa aagagctgct taaagccgta aacttcatgg
     3361 tgcatgaatt agaacgtcgt aatatattgt ctccgaaaat cgaagaatta aaagaacaaa
     3421 tcgatatcgt gagctaaaga acgagaaact aaaagataat caaaaaataa gtagaaaaaa
     3481 cagcgtacca gttttgactt tatcttgaaa aagaggctgg gacaaaagcg tttaactcca
     3541 agaaataaga ag
//
LOCUS       DBBGSP010000136         3499 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000136 DBBGSP010000000
VERSION     DBBGSP010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3499
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.138"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            201..500
                     /locus_tag="ACIZE9_003113"
     CDS             201..500
                     /locus_tag="ACIZE9_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094906.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            765..1640
                     /locus_tag="ACIZE9_003114"
     CDS             765..1640
                     /locus_tag="ACIZE9_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094907.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            1637..1855
                     /locus_tag="ACIZE9_003115"
     CDS             1637..1855
                     /locus_tag="ACIZE9_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094908.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            1842..>3499
                     /locus_tag="ACIZE9_003116"
     CDS             1842..>3499
                     /locus_tag="ACIZE9_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HGC6094909.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETG"
BASE COUNT         1311 a          420 c          688 g         1080 t
ORIGIN      
        1 ttttttctcc tttttatttt taaagatagt atatcatatt tataaaataa aagtatttaa
       61 aagtatttac tttttatctg gagtatgata ctttattctt ataaatacaa ataaatacat
      121 ttttttacgc aatttgtatt tatttgtact tataaaggta gaggagttat agaataatta
      181 attaaaaagg agaggttttt gtggaagcaa taaaattaat gatttcagaa gaacaggagg
      241 aaatgtttct aaagcagttt tatcaaattg ctacaaaagc tattgaaaag gctcaagaaa
      301 atgcggggat gacaagggaa tatctcaatc aaaaagaaat ggcggaatac ttaaatgtga
      361 gtgaaaactt tttaaaaaat gctgtgagaa atgagggatt gcccgtagtt gaattagggg
      421 caagaaaatt ttattcgaaa aaggcagtta atgagtttat gtttgctcga atgaaaagag
      481 gggaaaatat tggaagatga tgaagtagaa attataaaaa aatgctttaa aaaaagaaaa
      541 aaagtgttcc caaaagtttg cagactgggg gaacactcaa taataaagtg ctgagaaaac
      601 tttatttata gctattatat caaaaaagaa ggtgaaaagg tgttttcttc tggaaatgtt
      661 gtagttgaca aacttagaga aataaatttt gacggaaatg taatccacac acatggtacg
      721 atcaattaag aaaaaaaacg aaaaaaggtg ttgagaagcc ctatttgaat gcaatagtta
      781 tcttagcaga aattacctat tggtatagac ctaaaaaaat ttttaacgat gatggtcagc
      841 tacttggtta tcaaaaaaag tttcttgaag atattttgca aaaatcatat aagcaattaa
      901 gcaaaaaaac aggattatca gaacgagcta taaaagatgc aattgtgtac ttagagaaaa
      961 aggggattat caaaagggtt tttagaaata tttattatga gaaaagagca gttacattat
     1021 caaatgttat gtacattgtt ttaaatgtac ataaattgat agaaattact tttcctactt
     1081 tggattgcga aaaaaaggag tatatgccga aaattcgtca gaggggtatc gaaaaaaaga
     1141 gatatgtctc tttaaaaaaa ggtagaggta tgtacaaatt tgtatatacg tatacaaaga
     1201 ctacttcaca gaacatatca aagactactc tcgttatgga agaagaggat attaatataa
     1261 agaggattta cagtaagatt agtgttcttt atgacgcaaa taacgaagat ggtcgaaaat
     1321 tatttcaagt gtatcactat ttgagaaacg ctaatgtaga tacagaagat atcagaaaaa
     1381 tcattgaata tttatctgaa aatactcagt atcttattgc tgagtgtatt ataaaacaac
     1441 atgaagcatg cttttttcaa agaaaaactg aagaagggtt atacgattat gtaacatatt
     1501 ttttgaatgg acttcagaaa agatataaaa gtcaattttt agaaaatgta gagcctatag
     1561 atcagttcaa aaaagctttc gaaatcaaag agttacctga aattactatg cataattggt
     1621 tgaaaggaga agaatcatga ttaaaaatcg cttaatagat caaatgtggt gtcttgatca
     1681 aaatacagat actctcgaat taatcgagag tatctgcttc aacacagtag ttctcgattt
     1741 aagagctgaa aatgacaatt gtgtaactca tatcataatt aatcaaaaaa tggctcagca
     1801 gctctctgag agcctaagaa aatgggctga aggagaaaac tatgaaagca attaaagaaa
     1861 aaatcgttag tagaaaaata aactggttag cactcagtgt acttgtttta atgattagcg
     1921 ttgtttttac aagtaatatt gttgaagcta gcattttcaa ttggtttgat gacacaaaaa
     1981 gtcaaacaga gtttttgaat aattctcttt atagacctta cctaaaaaaa tacaatggag
     2041 atttccttag tcagttcggg atttggcttg gatgggctgt ggtaaaaggc atgtttactg
     2101 tgactgattc gattcaaaat atgattccag atgtgttgga tttgttcaat ttcattgaaa
     2161 gtacagggct aaataatgtt tatcaatcag tcataaatac aattgtcgtt ggattaatga
     2221 tcctttcatt gatgtttgtt ggctacaaga tgattactgg aaaaggaaca atagatttaa
     2281 gatctgttgg aatgaatata gtgatgtctg tagcgttaat tcttttaatg ccaacaatga
     2341 tttctagcgg tattcaattt gccaaaatat tttacaatga tgctactacg attacaaatt
     2401 cagatgacgg agtcgcttgg tcattgataa aacaaggagt aacagatctg gcatatatta
     2461 ataaaacaga tcaatactca agcattgata aaacggagga tcgaaataag ttaacacgaa
     2521 aaaattttca acagacagat ttaacacaag tgttgacgga taaagtgatt gataaattgg
     2581 aaaaagaaaa tccagctgcg gataatcttc gctatgaatt agttgaaaat tctaataatg
     2641 aatttgttgc cacaaagttt tctgataact tcttatcaac attttctgat agcttgaaat
     2701 caggttatta tcgatatcaa gcaaatcttt gggggatttc gattgggttg acagcgttgg
     2761 caatcgccta tgtgttcagc gcgtttgtga tcattacagc aatattagaa cttgcattta
     2821 aacgtgtgtt aggtgttctt gtttttgcga cagatattga aacaggacaa cgttcaaaag
     2881 ttgttttatc cgatatttta caatgttact taacagttgg atttcaaggg tttggactat
     2941 ctatgtttgc tatgtttatc aattttttaa atgctggaca aggtatctcc acaaatattt
     3001 ttataaaaac aattgcttat atctgtgctg tgtttgtgct gataaaaggc agtggaacag
     3061 tcatgagata ctttggtgtt gatattggac tcaaagaagg ctatgggcaa cttgcttctg
     3121 cttttggtat gggcgcaatg ctgtttagaa aaggatcaac tggatttaat cgtgctaaag
     3181 gaagcggaaa tggaaatgga tcagacagtg gagaaggaga agatcgaaaa ccagaaaaga
     3241 atttcggcga aactctatca aaaaaagctg gcaaaactgg aagagctttg ggatatgccc
     3301 atgaacgtgg attatcaggt ttagcttcag atggagctac aatggctagt gaaagagcaa
     3361 taaaaccatt taagagtatg cgtgatatgg ctaatgatac caagaataag ttcaaagaag
     3421 gtttagatga tggtacagtg tccgctatta ataaaaatag caaacctatg ttagctaaaa
     3481 ataaagaaga tgaaactgg
//
LOCUS       DBBGSP010000137         2768 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000137 DBBGSP010000000
VERSION     DBBGSP010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.143"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(75..1874)
                     /locus_tag="ACIZE9_003117"
     CDS             complement(75..1874)
                     /locus_tag="ACIZE9_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGC6094910.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(1998..2594)
                     /locus_tag="ACIZE9_003118"
     CDS             complement(1998..2594)
                     /locus_tag="ACIZE9_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HGC6094911.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT          976 a          522 c          480 g          790 t
ORIGIN      
        1 aaaacgcata tacctgcggt ggcaggttat gcgttttttg ttgtataaag acttttttca
       61 ttaacgattt ttgattagcc gactcccaaa acaaaattta gcagtttatc tgaataagtg
      121 atttcttcat ctgtttgttt cacactttca tttagtagtc ccatctcatc ggttatgata
      181 ccatccacac cataaaacat catgcgactc atagcatctg aatcgttgat tgtccataca
      241 tatacttctt ttccgtcttg gtgggcagaa ttaatgaagt tacggttgat cgtactatat
      301 tccattgtca gaaaatcagc aggcgtcaca gggggcccaa caatattgaa aggtaagatg
      361 tagcccacat aaaagtttgg ttctgcttct tttaaatctg aaacggtttg gtacgtcaaa
      421 ctttgcaaaa tatgatggtt ctctaagata actttgcggt atttatggac aaatcgttcg
      481 acaaggtcat ccgaatcttt tttagaggtc ttgatctcaa taagtaattt ttggtttagc
      541 ttatgtgctt tttccaaata agaatcaaaa gaacaaacag gggcttgcac tccgttttca
      601 gtaactgtaa gatttgtcaa ttctttcaat gtaagatcct gtggtgttcc atttacccct
      661 gttaagtgac gaagatttgc atcatgcatc actacgaaat gaccatcttt tgtttcctga
      721 acatccatct ctacataatc aggatgatag tctctgcttg ttttttcaag tgcttctaaa
      781 gtattttgcg ccccattttg ggtactcaca cctctgtgag agacagtcac tggttttgtc
      841 tgaacagctg aagtcagata atccatattg taaagacaga cgccaatacc gaaaaaaact
      901 gcaaaaagag tcaaaccagt gtttttcagc gcagagaaac gcaagttggg ggcttgtggg
      961 ataaaccact tagggatctc aggcaagaag ccttcgtcat ccatgaaatc aacaatgata
     1021 taaaaaatcc ctacggtaga catcacgata ttgaataata aaatcccttg taaaagcgtc
     1081 atagcaaaca cagcgctgat caatgcatag tctgggaaaa attgttcaac catactttgt
     1141 gccaaaataa caacgatata tcctaaagaa gaaaggagta aaatcgtacc gccaatcaca
     1201 ataaattggc ccgtgatggc caaaagacgc gatttggtca atgaccagct ttcccgaatg
     1261 gctgctcgaa aaggacgatc tcgtagaatc atttccggta aagcaaaaat cagtcgaatc
     1321 ccaatatagc caaggaaaat ataaacgagt aaaaaggaac tgacgatgat ccaacgatta
     1381 gcaaaaataa aatccataat gaaagcgggg atttttattt ttgacagtag atcagaatta
     1441 aaacttaatc cgctgatcgg tagaatcaat aaaaaataag caaggaaaaa caaaaaagta
     1501 atgggtctca ctttcttcag ctgaagtatc gtcaagtgta agagttgctt caaagagatt
     1561 ggttctttct ttttaataaa aaaaacactc atcaaaagaa aagtaaattc gaaataaact
     1621 aacagtaaaa tcgtcatcaa aactacgatt aacgagagta gaaccccagg atgttgagaa
     1681 aaaattgaag gaatattgtc ataagacaaa tagtcaattg cccctcggtg taaaataaaa
     1741 cgggtcgtac tgctcaataa gggtaaacaa ataaataaaa taaagccatg catcagcaag
     1801 acatcacgga aataagcttg tgttcctttt aaaaagtccc aagcattacc taagctacgt
     1861 ttcaaataat tcatcctatc acctgctctt cacattgtag cgcaaatcta atgaaaaagg
     1921 aaagggtgca gtgtgttttg cagacccttt cccagattta acattgtcaa tcaatgacta
     1981 attttacaaa ataaatatta tccaagaaga ccacttagat attgacctcc ataaatcaag
     2041 gccatactat ataagaaaat cgacagtggt ttagcaatca aaatgattag tgtatatcgt
     2101 ttcactgaca tgtttgtcaa tccagccatc aaacataacg catcgtcagg agcaactgga
     2161 agaaaaatag ctagagcaaa cagcttctca aaacggtttt gattatccag ccagccaata
     2221 tatttgttat atgtcttatc gctaatcatg gaaagtatga atggctttcc ataacgacgc
     2281 cctagcagaa aaatgataat cgaaccaatg cagattccaa tatagttata gataaatcca
     2341 gcataagggc caaatatcag gacaccagct gcagtactga tccctccagg aatgattgga
     2401 ataactactt gcaggatttg gatgaagaca aaaataatcg gtcctaaaat gatggaatca
     2461 cctactaatc ctcttaacgc attcaaatct ttgaaaacac ctaaattaat aaaataaatc
     2521 gtcagcgcga ttgataggcc taatccgata atggatatga aatttatcag ttttcgagag
     2581 gcagcaatat tcattattca tcaactcctt agaggttctt tgttaactat actttactag
     2641 aaaagcaact aactgcgcca ttttttgata tgacagaaaa caaacaattt tgtaagttca
     2701 tcataagtat aaaagattga tctcaaaaaa acatccaact aaagacttat ttaataactt
     2761 gttttttt
//
LOCUS       DBBGSP010000138         2578 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000138 DBBGSP010000000
VERSION     DBBGSP010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.145"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(45..1364)
                     /locus_tag="ACIZE9_003119"
     CDS             complement(45..1364)
                     /locus_tag="ACIZE9_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC6094912.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="ACIZE9_003120"
     CDS             complement(1361..2014)
                     /locus_tag="ACIZE9_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC6094913.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..>2578
                     /locus_tag="ACIZE9_003121"
     CDS             2302..>2578
                     /locus_tag="ACIZE9_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGC6094914.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQT"
BASE COUNT          854 a          403 c          250 g         1071 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgaca ccttctgttg
     2101 ccaatacttt ttcttttttc taataaatgc aaacagacac cttgaaatcc tttagaataa
     2161 agggttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tattgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagacct
//
LOCUS       DBBGSP010000139         2465 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000139 DBBGSP010000000
VERSION     DBBGSP010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2465
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.147"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            223..870
                     /locus_tag="ACIZE9_003122"
     CDS             223..870
                     /locus_tag="ACIZE9_003122"
                     /inference="COORDINATES: protein motif:HMM:NF014505.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGC6094915.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRGIIDES
                     DLNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQKVFNC
                     YKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFTK"
     gene            1153..1226
                     /locus_tag="ACIZE9_003123"
     tRNA            1153..1226
                     /locus_tag="ACIZE9_003123"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1187..1189,aa:Ile,seq:cat)
     gene            1772..2338
                     /locus_tag="ACIZE9_003124"
                     /pseudo
     CDS             1772..2338
                     /locus_tag="ACIZE9_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
BASE COUNT          886 a          351 c          447 g          781 t
ORIGIN      
        1 tgcaaatttg tccataactt attgattatc ttgtaaaaat gcggtaattt aatagttagt
       61 gagaagaggt gcttaattat agttaaaaaa gaggaaatag aagcagcatg taaccaagca
      121 aatgttaggt ttattggaga agctttatct ggatatccta agtataaata cttacacaac
      181 tggttacaaa gtaaaagttt ttatcttaat aaagaaagat gcatgcctaa taaaaattat
      241 agggtttata aaagaggaac tattgtatat gttgattttg gggtgaacgt gggttatgag
      301 ttatctggta atcattttgc tattgtttta aataataaag ataattcgaa aaatggtgtt
      361 gtatgtgtag taccaatctc ttcaaaaaag aaaagtaatt atgtatctgt aggaaaaata
      421 ttagaagttg ctagtattaa acaatttata agccaagctg ataaattaaa agagaaactt
      481 aggataatta ttttactttc attaaataga ggcatcattg atgaaagcga tttgaatagt
      541 tttattaaag atattgaagc taaaggtgaa aagctttcag tggaagaagt agaaaaacga
      601 gctgtaaaac ataatttggt ttgcgagaca agggaacaag taattaaaga aataaaatca
      661 ttatctgaag atatggtaaa atatcagaag gtgtttaatt gctacaagaa atatacacaa
      721 gaatcctatg taatgccact taatatccaa acgattagta aaaatagaat tagaagaatt
      781 aacaagtttg atccttctgg aaatatgaag gcacctggaa atgtcctcaa tgaagtagat
      841 gaaagtttaa aaaaatattt tacaaagtaa acgatatttt tgttgacatt tttctgttcg
      901 ttagttacca tgtagttata gaaggacgta agcgcctatt tttaatgtac acatcgggac
      961 gtatgcgccc acatagaaac atagttgaga gacatctata tggtgtctct ttttttatta
     1021 atatgcaaaa aagtctagtt ttttcaataa tatttatgta ataataaatt agccaccaca
     1081 acaaagaatg aaacccatta ttatctagtc tatgtccatt ctttttgttt gcagtagttg
     1141 tgatggcttt ccgtactctt agctcagttg gttagagcag acggctcata accgtccggt
     1201 cgtaggctcg agtcctacag ggtacatact ctaagtgatt taaattgcga ataaaatata
     1261 aaaatgactc cccttttgac tcccccaagc agtatatgga tgtctctaaa agttgttttt
     1321 ttagataata aaaagctgat aataagcgaa aaacacttaa aatcagcttt aaaccctatt
     1381 ctcgaaatcc ggcgaaccgg ctaataccgg cgcgcaggtt caaatcctgt accttcctta
     1441 tatcaacgat tagaggttgt gaagaagctg tcctgcatca agtaataaga acggccaaac
     1501 aaaaatagct tttcctattt tttcgtttga ttgggcttat taccgcagat gcaagctttt
     1561 gaacaccgtt tgttcggaat aaggggctgt gacaagactt ttgtcacagc cccttattgt
     1621 tgtactttta acctacaata ttttttgatt ccccctgagt actatttttt ataaatgcta
     1681 gtaaatcaat cttctttggc ctttttttga taaaaaaaat actagatgta agataaaagt
     1741 gtaaaaacga tttgttttag gaggggaaac gatgtgtacc gcaatcactt atgcaacgaa
     1801 agaccattat tttggaagga attttgatta tgagatgtct tataatgaag tggtcactat
     1861 tactccaaga aattatcgtt tcgattttag aaaggtaaaa aatttagata aacattatgc
     1921 aatgatagga atagcagctg gggtatccaa ctatccactc tattatgagg ctacaaatga
     1981 aaaagggttg agtatggcag gactgaattt tcctggcaat gctgattata aagaattaca
     2041 agaaggaaaa gataacgttg caccatttga gtttattcca tggatactag ggcaatgctc
     2101 aaccatagac gaagctaaag aattattggc tactatcaat ctagtcaata tcgattttag
     2161 tgaaaaacta cccttgtcac ctttacactg gttattagct gataaagaaa aatcgatagt
     2221 aattgaaagt atgaaagatg gacttcattt atatgataat cctgtcggtg tgttgacaaa
     2281 taatccgcca tttgattatc aattatttaa tctgaacaat tatcgctcgc tatcaaatgg
     2341 aacgagagta taaaatattt tgtgtaaatg aaaaaatcca tacaaaaaag gaagtccctt
     2401 ctgtagaata aagttaacga caaccaattc acagaaaaga ggacttccct atgaatgatt
     2461 ttact
//
LOCUS       DBBGSP010000140         2418 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000140 DBBGSP010000000
VERSION     DBBGSP010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.148"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            442..528
                     /locus_tag="ACIZE9_003125"
     CDS             442..528
                     /locus_tag="ACIZE9_003125"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGC6094916.1"
                     /translation="MFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(831..1055)
                     /locus_tag="ACIZE9_003126"
     CDS             complement(831..1055)
                     /locus_tag="ACIZE9_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094917.1"
                     /translation="MEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNMTPERKRS
                     LEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1421..1705
                     /locus_tag="ACIZE9_003127"
     CDS             1421..1705
                     /locus_tag="ACIZE9_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094918.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            1708..2124
                     /locus_tag="ACIZE9_003128"
     CDS             1708..2124
                     /locus_tag="ACIZE9_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094919.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(2261..>2418)
                     /locus_tag="ACIZE9_003129"
     CDS             complement(2261..>2418)
                     /locus_tag="ACIZE9_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HGC6094920.1"
                     /translation="PALRELKKYFNDLKVTKIKAKKGNKIAKLEFTFSSLTSDLPKIS
                     LRNWLEE"
BASE COUNT          795 a          451 c          390 g          782 t
ORIGIN      
        1 aaaagggttc taaaaaatct ttaaaaaata aataaaataa acgcgcgcgc gcgagcaaaa
       61 tttcccgcca aaaaatcacc cactttttaa aataaacagg ttcgcgcatg atattaaact
      121 gccaatctag ctccctatgg tcgctgtaag aaggagtgat cgctacgctc tcacatttta
      181 cttgcagcag tcgcctttag gctccttcgc caaaaataat tcattaggga ctcctttgtg
      241 gcgtcctgag agctcgtcta agccgttcta agacaagatt cgataaaaac tatgtccttc
      301 gttctaaagc gccttacagg cggtcagggc aagccctaac aaccccaagg caataaaaaa
      361 cttaggctta tttttgcttt tttattgtat aattgattgt cgcctatccg acagtcttgc
      421 gactggaagg aggtgtgttt cgtgttcact aactttattt gctcccttct tgttgggctt
      481 ttaagcgctt tgttcagtta ctggttgaat aaccgaaaca agaagtaaaa cttaattaag
      541 gcgactcagc ccacaaaaaa agccccagag aatccgacct ctctggggct ttcgtgtgtt
      601 tcgtgttcac ttatttgcaa tcaaattata acagaaataa atatttattt caaaaatatc
      661 ctacaaaagt ctaaaatccg taattatttc ttatatgcaa catttacaaa taaagtcgct
      721 ctgagagctc gtatttttcg atttaagacg ttttatttag tttttggtgt attttcattg
      781 gtccaagcta aaaaactctt agaagcgatt ttagagccat ttaaacccac ttaattatat
      841 tctccatgaa attcgctcca tgcgtcaaaa gctgcgtctg aaattccgcc gtcttcgttc
      901 actagttgca ttaatttttc caacgatcgt tttctttcgg gtgtcatatt tttatattcc
      961 aacaattttt cgtctgttaa atcgaacttg attgcttgaa ttgcttgctc taatttttct
     1021 aagttttgaa aatattcgta aggaaatttt tccatttttt ctttctccag tctcacaatt
     1081 tttctagaaa taaaatcact tctttgccgt ctatactctc aaaaaaaatg tcgtttgaaa
     1141 aactaaataa atttttgatc gtgcattttt aaatttggtt atcgattaca cgtgcagcac
     1201 tcccccccga attttaaaga gcataaggaa acgtgtaccc actttctaaa aaaagtgggt
     1261 agataggctg tgcctatcac gtttctcaga aaaaaatttg atatcacttt ttcgccatcg
     1321 tgggtagctt atgtatagca ttttggcaaa aaacagctat acaaatatag tatttgtatg
     1381 gtatacataa attatacata attgcaaaag gagatttttt atggacattt tagttcggaa
     1441 tattgatcca aagtttgttg caacaataga caaacgttgc caagaactca cgaataaaac
     1501 aggagaaaaa tggagtcgaa ataaatatct aaaagtttta atcgaaagtg attttgaccg
     1561 tcaacttacg acttacaaaa aagaccaatt cgatttattg ctcgataaat ttattgctat
     1621 ccaaacagaa aatactcaaa tattaagcga gtatgtctac acaaataatc aaatcattga
     1681 aatgcttatc ggaggaatga tataaccatg agaaaaactt ctgtccaaaa acatgttact
     1741 ttgtacccta gtcatgttga cgttttagat tccatcatcg aaaaaaatcc agatatcaat
     1801 aactactcgg aagccattcg ctttttatgt atgagttatg aacccgatac caacacgacc
     1861 actaccagca atcaggcaaa actaaatgct atgggaaaag aaatttccat catgactgaa
     1921 atcatcgcag aatttgctga tttatatcta aaagatacag gcgttcttat tggcacaaat
     1981 tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta aactaaatcc atcaaatcga
     2041 aatcgaccaa agaatcatca aaaagaaacc agtcaaacag tcacttctag aaatttcgac
     2101 ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt attcctatct gttttttatt
     2161 tagaagcccc atacaatatg ctagaatgta ctagcaatct tagtcggttg taagggactt
     2221 gtctacttgc ttaatgtaag gggggcgagt tcttttttat ttattcttct aaccagttac
     2281 gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa agtaaattct aatttggcga
     2341 ttttattgcc cttttttgct tttatttttg tgactttaag atcattgaag tattttttta
     2401 gttctcgtaa tgcaggat
//
LOCUS       DBBGSP010000141         2398 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000141 DBBGSP010000000
VERSION     DBBGSP010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.149"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            207..2069
                     /locus_tag="ACIZE9_003130"
     CDS             207..2069
                     /locus_tag="ACIZE9_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC6094921.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="ACIZE9_003131"
     CDS             2069..>2398
                     /locus_tag="ACIZE9_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGC6094922.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DBBGSP010000142         2313 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000142 DBBGSP010000000
VERSION     DBBGSP010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.150"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            191..445
                     /locus_tag="ACIZE9_003132"
     CDS             191..445
                     /locus_tag="ACIZE9_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGC6094923.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="ACIZE9_003133"
     CDS             446..763
                     /locus_tag="ACIZE9_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGC6094924.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1322..2257
                     /locus_tag="ACIZE9_003134"
     CDS             1322..2257
                     /locus_tag="ACIZE9_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094925.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          846 a          313 c          434 g          720 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     1441 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     1501 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     1561 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga
     1621 atatctcaag gggaatagct atctcaagat tcgattttca catatattaa ttttactacc
     1681 atatttgaat gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa
     1741 tcaaggaaat atgaatatta caagtaacaa aacgtcacgt gtgctattgg cgttgatggg
     1801 ttacggaatt ctttatagag atgaccaaaa tggccagatt ctaataaatc gggctgggcg
     1861 ttcattatta atgaaatata gaaaatttat accggaagat tttcaaaact tacagttaga
     1921 aaacatgcgt ttagaagatt tatttagatt agcagaagat gataagtata gatttgaagt
     1981 tttgaaaatt caaaagaatg aactattgaa taagttatat cctgagaatg cgataaaagc
     2041 acattttggt gatgctaatc atatgtatag ttggttcatt cctaaaagat ttagagggaa
     2101 aatcaatgct ggagatcaag tgaaagtact caatcgaaat agtacagatg tcgtaatgat
     2161 aacagatatc tatgtagaag atgaagatat aatcaaatat atgaagcctg tgataaaact
     2221 tgttaataaa aataaaggaa cccgtggtgc tagttaattt tttcctagag aaaaatgtct
     2281 aaacatgttg gtaaatcaac aaaaaaacgc ata
//
LOCUS       DBBGSP010000143         2293 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000143 DBBGSP010000000
VERSION     DBBGSP010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.151"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(51..1598)
                     /locus_tag="ACIZE9_003135"
     CDS             complement(51..1598)
                     /locus_tag="ACIZE9_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HGC6094926.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="ACIZE9_003136"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="ACIZE9_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGC6094927.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="ACIZE9_003137"
     CDS             complement(2043..2237)
                     /locus_tag="ACIZE9_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094928.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          644 a          477 c          408 g          764 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga aaacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agt
//
LOCUS       DBBGSP010000144         2056 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000144 DBBGSP010000000
VERSION     DBBGSP010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.153"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            493..714
                     /locus_tag="ACIZE9_003138"
     CDS             493..714
                     /locus_tag="ACIZE9_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094929.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="ACIZE9_003139"
     CDS             715..972
                     /locus_tag="ACIZE9_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094930.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKAAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="ACIZE9_003140"
     CDS             complement(1108..1710)
                     /locus_tag="ACIZE9_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HGC6094931.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKIRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="ACIZE9_003141"
     CDS             complement(1777..1932)
                     /locus_tag="ACIZE9_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032993 - protein-DNA complex [Evidence
                     IEA];
                     GO_process: GO:0006276 - plasmid maintenance [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGC6094932.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          464 c          313 g          601 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggcggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaat cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatca ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DBBGSP010000145         1988 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000145 DBBGSP010000000
VERSION     DBBGSP010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.154"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            113..1438
                     /locus_tag="ACIZE9_003142"
     CDS             113..1438
                     /locus_tag="ACIZE9_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HGC6094933.1"
                     /translation="MFDYSREPVNDYFLIDMKSFYASVECIERNLDPMTTPLIVMSRS
                     DNTGSGLTLASSPTAKKKYHITNVSRATDLPYPLPKELHIVPPRMNLYIKKNMEVNQI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTSSGTRSERRRELAKIIKDEIQKETGLIA
                     TVGIGDNPLLAKLALDNEAKSSKEFIAEWTYETVPEKIWKINEMTDFWGIGSRMKKRL
                     NHMGIMSIEDLANWNPYTIKSQLGVIGLQLYFHTNGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPKDYTRREEVELVVKEMAEQVAIRIRQHNCKTGCVRLAIGTSILEEKSGFSHQMKI
                     PITDNTKELQNYCLFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEEN
                     LDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            1431..1778
                     /locus_tag="ACIZE9_003143"
     CDS             1431..1778
                     /locus_tag="ACIZE9_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094934.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
     gene            1775..1957
                     /locus_tag="ACIZE9_003144"
     CDS             1775..1957
                     /locus_tag="ACIZE9_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094935.1"
                     /translation="MNIIKKYEFGYITYEQLIEELWGYGQQLINEVGIDCFCFYIESG
                     AGYHKNRYYIFPYPPK"
BASE COUNT          746 a          271 c          389 g          582 t
ORIGIN      
        1 caataatctc ttttagtcag acttttagtc tgactttttt gtatttccaa aatttattct
       61 ttacaaaaac gaacatacgt ttgtataatt gcttgtgaat gggggaataa aaatgtttga
      121 ttacagtaga gaaccggtga atgactattt tttaatcgac atgaagtctt tctatgctag
      181 cgtggaatgt attgaacgaa atttagaccc aatgactaca ccgttaattg tcatgagtag
      241 atcggacaac actggttcag gtctgactct agcttcttca cctactgcaa agaaaaaata
      301 tcatattact aatgttagta gagctactga tttaccttat ccattaccaa aagaacttca
      361 tattgttcca ccacgaatga acttatatat aaaaaaaaat atggaagtta atcagatttt
      421 tagaaagtat gtcgcagatg aagatttatt gatttattcg attgatgaat caattttaaa
      481 agtgacaaaa tccttaaatt tatttactag ttcaggaaca agaagcgaga gaagaagaga
      541 attagctaaa ataatcaaag atgagattca gaaagaaaca ggtctaatag caacagtcgg
      601 aataggagat aacccattat tagctaaact tgcactggac aatgaagcga agagtagtaa
      661 agaatttata gctgagtgga cttatgagac tgtacctgaa aaaatatgga aaataaacga
      721 gatgactgac ttttggggca ttggatcacg catgaaaaaa agattgaatc atatgggaat
      781 tatgagtata gaagatttag caaattggaa tccctacaca attaaaagtc agttaggtgt
      841 aatcggactc cagttatatt tccataccaa tggaattgat cgtacggata ttgctattcc
      901 accagaacca accaaagaaa agtcttatgg gaattcacaa gttctaccaa aagattatac
      961 gaggagagaa gaagtagaac tagtagtcaa ggagatggca gagcaagtag ccattcgaat
     1021 tagacaacac aattgcaaaa ctggttgtgt acgcttagca attggtacgt caattttgga
     1081 agaaaaatca ggtttctcgc accagatgaa aataccaatt acagataata cgaaagaatt
     1141 acaaaattat tgtctttttt tattcaataa gttttatgag gggcaggaag tacgacatat
     1201 aggagtaact tatagcagat tagtatacac agattcccta caattagatt tatttagtga
     1261 tccaagaaaa aagattgctg aagaaaattt ggataggatt attgataaga ttagacaaaa
     1321 atatggattt acagctatta tacatgcttc atctatgtta gaaggtgcaa gaagtattac
     1381 gagaagcact ttaataggag gacacgcagg aggattagga ggtttgcata atgattgaat
     1441 ataacgatag aggacgttta aaatggtcgg gattttattt gtctgatcat actgaaagaa
     1501 tcaatgcaga caatgtacaa cgtgctaatc ataatttggc aaaagaacaa atgacgactg
     1561 aagagattgc gaaaatactg agaactgctg tcataaaaaa tagacccgtc tgcattcaaa
     1621 aagaggaacg aaacgctgaa ggttactatc cagatgatgt agtaggaaaa attattggat
     1681 atgacgagct tggtgtattt gtggaagaag aaaaagttca ctatgatgaa attaggaatg
     1741 tttctttctc ggaattatta aaatggagtc agatatgaac attattaaaa aatacgaatt
     1801 cggttatatt acgtatgaac agctaataga ggaattatgg ggatatggtc aacaattaat
     1861 taatgaagtg gggattgatt gcttttgttt ctatattgaa tccggagcag gataccataa
     1921 gaacagatac tatatatttc catatccacc aaaatagtct cttagatatt tttaaatttt
     1981 ctcatact
//
LOCUS       DBBGSP010000146         1753 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000146 DBBGSP010000000
VERSION     DBBGSP010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1753
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.157"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..1594
                     /locus_tag="ACIZE9_003145"
     CDS             <1..1594
                     /locus_tag="ACIZE9_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HGC6094936.1"
                     /translation="AEYSPEQINRMIDQMESVKKESYLDPTVFEAEEHIQKVIHKMFR
                     PDNAYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREG
                     RTMEDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDI
                     NNRLARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTN
                     RTYPEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGK
                     LKEVSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQL
                     LEEQIGVYETVKGSLMEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAAN
                     SSDAREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNL
                     IHAFSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQ
                     EMKRAWRKMLDDELIPLENELR"
BASE COUNT          634 a          282 c          356 g          481 t
ORIGIN      
        1 tgcagagtat tcaccggaac agatcaatcg tatgatcgat caaatggagt ctgtcaaaaa
       61 agaaagttat ttggacccta ctgtttttga agcagaggaa catatccaaa aagtcattca
      121 taaaatgttc cgtccagaca atgcctatac aaaatttgat tttcgaaatg gccgtccaac
      181 gaagtctgcg atcttaacca cgagttccat tgatatggcc aaaaagtatt atcgggccat
      241 caaagagatg acgaaagaat ctgattggtt aataaaagag tttcccaatc agcctatccg
      301 tgaaggacga acgatggagg atcctgattt cccacgaatc gctattacct attcattaga
      361 agaaaatagc cgagattcaa gtgcccaaca agaagaaatg caaaaaatta ttgaggaata
      421 taatcagtat tatgatactg cctggtcact agcagacatt gagcgttata acggagacat
      481 caataatcgt ttggcacgaa aaagagcgga attcaaacaa tttgggaaac aaatcgattt
      541 agtaatcgta gtggatcgtc tattgacagg ttttgacgcc cctacgattc aaaccctatt
      601 tgtggatcgt aatctagagt atgcaggatt gatccaagcc ttttcacgta cgaaccgtac
      661 gtatcctgaa aaaacaaaag gactaattgt tactttccga aagccagcga caatggagaa
      721 gaatgtcgag gatgcgacaa aactgtattc agaagctaaa gaagaatcgg gtttgattta
      781 tccaagttac caagaatcca aaaaaagatt caagcaagca tatggtaagt taaaagaggt
      841 ttcatccatg gaatccattg atgaacatac gccacttgaa atccgtatcg agtacgtcaa
      901 agcatttcaa gaattgaatc gtgcgtatga atcgttagtg acttatgatg attacaatga
      961 tgacatggtg caatcttcaa ctttgaacaa tcaaattcaa cttttggaag aacaaattgg
     1021 cgtgtacgag accgtgaagg gttcattgat ggaggaagaa ccagaaaaag agggagaaga
     1081 tttttcaacg atcgaatttt atagtgaaaa taccactaag ttgtatgata ttgattctac
     1141 ttatattgat caattactag gaacttatgc tgcgaatagt tcagatgcac gagaagaaat
     1201 tgaaaaagct ttggctaaat tgaataaaac agaaggagtc aaagaagttt accgacaaat
     1261 tttaaatgca tttgatgtgg ggactttaga tagtaatgaa gatatctttg tcattaaacg
     1321 tcgctatttt acacaagcaa gtgataattt gattcatgcc ttttccaatg agtggtttgt
     1381 ttctgagaaa gaattacatg cttctaatct gcaatatatg ccaggtgaag atccaattcc
     1441 taatatgaaa gcaattatca acagtaagga ttacgaagga tataaagcca aacatccaga
     1501 agcgaaacca tttaaatacc cacaagaaat gaagcgagca tggcgtaaaa tgttagatga
     1561 tgagttgatt ccacttgaaa atgaattgag gtaaacgaga agagttaaga aaattgtacg
     1621 attcaaagat agtagtaaag tggaagtgta gaaaataggg atagatgtct ttttacttgt
     1681 tcacatttta taacggagta tttaagaaag ctattgaata atgattcttc catctttttc
     1741 attcatttac cgg
//
LOCUS       DBBGSP010000147         1725 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000147 DBBGSP010000000
VERSION     DBBGSP010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1725
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.158"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(464..763)
                     /locus_tag="ACIZE9_003146"
     CDS             complement(464..763)
                     /locus_tag="ACIZE9_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HGC6094937.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(769..999)
                     /locus_tag="ACIZE9_003147"
     CDS             complement(769..999)
                     /locus_tag="ACIZE9_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094938.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1258..1371)
                     /locus_tag="ACIZE9_003148"
                     /pseudo
     CDS             complement(1258..1371)
                     /locus_tag="ACIZE9_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
BASE COUNT          599 a          270 c          258 g          598 t
ORIGIN      
        1 tacaagctaa agcttttctt cattgccact caaatgagtg gcttttttat gtatcctttt
       61 atggattaat gaaaggatgt ttcacatagt tatatttctg tatatttgaa aagttttact
      121 ttgattttta aatagaaaga catttgggtt atattgtgag ataataataa agaagagttt
      181 aaagcgttcc ccaaaaacca ctgccccata agtgtgttac gctttaaact cttttatatt
      241 tgaagccatt aaaaagcata ccatattttt gaaaaaaagt gagaaaaaag gcttataatt
      301 ggagtggtag ttaattagtg acttattttt gattttatag cactgatact ataaaatata
      361 gatatcatca tattacacaa tcttaatact aacttaaaaa atatctcctt tcataagtat
      421 ggtgataaaa tccgttccgg gctacctttt taggtagcct actttaatct ttgtatcttt
      481 ctggatcaac gaaagtatac tttatatagt cataacgccg atgatcgctt cgagcgtcta
      541 gcacatcagt cacgatatca aacaaaaaat atacgtcttt cttcattcta gttttcgcag
      601 cagggatttt aaagtagttc ttattagaat agtagagatt aattaataag ctatcttcga
      661 ttgctaaaaa gaaaacttct gaatcccaca ccttataaaa atctttgaca aatctattcg
      721 aaggatcaaa tttaaaccat aattgcgtct cattaaaaag cataaccatt actccgatct
      781 atttttaaac ttagtctcta cctctaatat atatcgagtt tttattttgc cttcagagaa
      841 tactgtttct ttttttgcag ttacaggttg tttattttcg gaaaaagcta atatagctaa
      901 aattgaaaca tccatctgga atttgtcttt ttcgttgctt tgctcataaa aatctgcata
      961 ttcatcacta atattttttc taataaattc ttccatcata aagatcacct cgaaaagagt
     1021 atacgaacaa acgttctttt tgtaaaggtg gaatttatta tactaaataa ataggtgaac
     1081 aagtacttgt gccaaattat gtgccaaaaa aaatcgaatt taataaaaca caaacaaaaa
     1141 gaaatcctat tatgataaca tttcttataa taacaaacac aacagaagac gtgtaatagt
     1201 tagtcaggaa cgtacaaata acccctgtat cctttgcggt acagggggtt attttgtata
     1261 agtagacatt gtagtttcta aactgctatg tcctaaacgt ttcgatacgc taagtatatt
     1321 tactccttga taaagtaaaa tagatgcatg cgtatgtctt agtccatcaa taaacagtcg
     1381 aagagaaaat agggaaaaat tgattactaa agaaaaactt actaggtcga cggtgtagtt
     1441 gattttcata cttcaataga ttcgaattaa acgatttcga ttggcttata ccagtcctat
     1501 ccaacgaaag atatatcgtt cttaactcta gcggtataac ttgaagcttt acgtaaagcc
     1561 aatgggaatg aactggagat gactttttat tatttttagt aatagctgat gggttaatac
     1621 ttacaacttt ccttttcaaa gtaccatata aaaaaacggt ggggttgttt agcgaaataa
     1681 aggatctaag ccaatagctt agatccttta ttctatgctt tatat
//
LOCUS       DBBGSP010000148         1693 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000148 DBBGSP010000000
VERSION     DBBGSP010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1693
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.159"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(53..787)
                     /locus_tag="ACIZE9_003149"
     CDS             complement(53..787)
                     /locus_tag="ACIZE9_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGC6094939.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="ACIZE9_003150"
     CDS             1114..1524
                     /locus_tag="ACIZE9_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HGC6094940.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..>1693
                     /locus_tag="ACIZE9_003151"
     CDS             1517..>1693
                     /locus_tag="ACIZE9_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HGC6094941.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYN"
BASE COUNT          543 a          295 c          325 g          530 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aat
//
LOCUS       DBBGSP010000149         1642 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000149 DBBGSP010000000
VERSION     DBBGSP010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.160"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(1..>1642)
                     /locus_tag="ACIZE9_003152"
     rRNA            complement(1..>1642)
                     /locus_tag="ACIZE9_003152"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          348 a          507 c          350 g          437 t
ORIGIN      
        1 taagtcctcg atcgattagt atcagtccgc tccatacatc actgtacttc cactcctgac
       61 ctatctacct gatcatctct cagggatctt actttcttaa agaaatggga aatctcatct
      121 tgaggtgggc ttcacactta gatgctttca gcgtttatcc cttccctaca tagctaccca
      181 gcaatgccct tggcagaaca actggtacac cagcggtaag tccatcccgg tcctctcgta
      241 ctaaggacag ctcctctcaa atttccaacg cccgcgacgg atagggaccg aactgtctca
      301 cgacgttctg aacccagctc gcgtgccgct ttaatgggcg aacagcccaa cccttgggac
      361 cgactacagc cccaggatgc gacgagccga catcgaggtg ccaaacctcc ccgtcgatgt
      421 ggactcttgg gggagataag cctgttatcc ccagggtagc ttttatccgt tgagcgatgg
      481 cccttccatg cggaaccacc ggatcactaa gcccgacttt cgtccctgct cgacttgttg
      541 gtctcgcagt caagctccct tctgccttta cactcttcga atgatttcca accattctga
      601 gggaaccttt gggcgcctcc gttacctttt aggaggcgac cgccccagtc aaactgccca
      661 tctgacactg tctcccacca cgattagtgg tgcgggttag agtggccata acgcaggggt
      721 agtatcccac cagcgcctcc atcgaaacta gcgttccgat ttctacggct cctacctatc
      781 ctgtacatgc ggtacagaca ctcaatatca aactacagta aagctccatg gggtctttcc
      841 gtcctgtcgc gggtaacctg catcttcaca ggtactaaaa tttcaccgag tctctcgttg
      901 agacagtgcc caaatcgtta cgcctttcgt gcgggtcgga acttacccga caaggaattt
      961 cgctacctta ggaccgttat agttacggcc gccgtttact ggggcttcaa ttcgtacctt
     1021 cgcttgcgct aagcactcct cttaaccttc cagcaccggg caggcgtcag cccctatact
     1081 tcatcttacg attttgcaga gacctgtgtt tttgataaac agtcgcttgg gcctattcac
     1141 tgcggctgat cgtatgatca gcaccccttc tcccgaagtt acggggtcat tttgccgagt
     1201 tccttaacga gagttctctc gctcacctta ggattctctc ctcgactacc tgtgtcggtt
     1261 tgcggtacgg gccgctgttt tctcactaga agcttttctc ggcagtgtga catcaggaac
     1321 ttcggtacta ttatttccct ccccatcaca gcttgtcctt aagaaaagaa gcatttgact
     1381 cctcttcaga cttactgctt ggacagacat ttccgatcgt ctgcattcct tagcctcctg
     1441 cgtccctcca ttgctcaaac aaaaacaacg ggtacaggaa tatcaacctg ttatccatcg
     1501 cctacgcctg tcggcctcgg cttaggtccc gactaaccct gggcggacga gccttcccca
     1561 ggaaacctta gtcattcggt ggacaggatt ctcacctgtc tttcgctact cataccggca
     1621 ttctcacttc taagcgctcc ag
//
LOCUS       DBBGSP010000150         1555 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000150 DBBGSP010000000
VERSION     DBBGSP010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1555
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.161"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..300)
                     /locus_tag="ACIZE9_003153"
     CDS             complement(<1..300)
                     /locus_tag="ACIZE9_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HGC6094942.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            393..742
                     /locus_tag="ACIZE9_003154"
                     /pseudo
     CDS             393..742
                     /locus_tag="ACIZE9_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1014..1304)
                     /locus_tag="ACIZE9_003155"
     CDS             complement(1014..1304)
                     /locus_tag="ACIZE9_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094943.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT          502 a          297 c          220 g          536 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt tttta
//
LOCUS       DBBGSP010000151         1417 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000151 DBBGSP010000000
VERSION     DBBGSP010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.162"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(150..1337)
                     /locus_tag="ACIZE9_003156"
     CDS             complement(150..1337)
                     /locus_tag="ACIZE9_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HGC6094944.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          412 a          308 c          249 g          448 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttc
//
LOCUS       DBBGSP010000152         1387 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000152 DBBGSP010000000
VERSION     DBBGSP010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.163"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..106
                     /locus_tag="ACIZE9_003157"
     CDS             <1..106
                     /locus_tag="ACIZE9_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6094945.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(359..508)
                     /locus_tag="ACIZE9_003158"
     CDS             complement(359..508)
                     /locus_tag="ACIZE9_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094946.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            970..1182
                     /locus_tag="ACIZE9_003159"
     CDS             970..1182
                     /locus_tag="ACIZE9_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094947.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
BASE COUNT          516 a          206 c          227 g          438 t
ORIGIN      
        1 cgcatctaaa cgaaataata ttcctagaaa atcactggat tatcgaacac ctttggaagt
       61 atttttgagt tacgtaagta ttgatgatct gtctaactta atttgacaat taagattata
      121 ttaaatatta tacagataat aacggaatat tatcatcgaa acagctaaca aaattgtcat
      181 aaaaaacgag atggttgata ttagaacttg tgtttttgtt taggtctaga gataaagaga
      241 gacaatttcc aaatatatgt aatgaataca aaaagacgtt tgtcgcggat taccgttaca
      301 aacgtctttt attgattttc cgagatctca tcagtcgcca tttggaatgg ttcactcctt
      361 atctagattc gtttaatgct cggactgctt gttcgattgt aataccaaac gcaacgttat
      421 tttcgttttg tgcatcaatc gccataaaac ggttagaagt tgtatcaaaa gctacgcggt
      481 attgcatatt tgtttttgta aacgtcataa aattcatctc ctttgtaatg taatttagtt
      541 cttgaaagtt tcctttaaac tttcgaactt ataccaagtt tagcatcgta cgttttttga
      601 tgcaattaaa aagcatttat cattttcctt atttattttt tcttaaatgg tttagctatt
      661 ttcttttaat ccgataagta gcccaatcat caaggttaca aatactattg cttgaatata
      721 aatcatatgc tcacctcttt ataaataact tagcaatata aagaaaaaaa cgcacgaaca
      781 acataggaat ataaacaaac gtttttgtca caacgtctaa gatcgtgtta aaaaatagtt
      841 atctaaaaag cagaaagata ctcaaaataa aaaataaaaa aatggataaa aacgttttca
      901 aatacaaggt aatttgttat tataaaataa agaaaaaaca aaataaaaat aaagaaaaga
      961 gggaatgaaa tggtaaaagc agaagtagga agatcttata tatgcaaacc gatcggagta
     1021 tctcatgaac taatcggctg tattgaacgt acatatatca acacggctgt cgtgtatgtt
     1081 gaaagttatg accaacgaga ctatcaactt atcaatgaaa gcaagtatcg catgctcgta
     1141 aaattctgtg atattagcgc acctgctgaa ttggtttctt aaacagtatt tttgagaatt
     1201 cgcaagaact cccttataat ataaataaag acagaaggga gcgagaagat atgccaaaaa
     1261 gaaaaagttc agggaaaatg ggaattattc ttgcagtgat ctctgcaatt cctgctattt
     1321 tagctattgt tcgtgcgatg aaggaatcaa gagaaagtta agcacacatt atgagcgtca
     1381 aacaaaa
//
LOCUS       DBBGSP010000153         1374 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000153 DBBGSP010000000
VERSION     DBBGSP010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.164"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            33..1372
                     /locus_tag="ACIZE9_003160"
     CDS             join(33..474,474..1372)
                     /locus_tag="ACIZE9_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HGC6094948.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          576 a          177 c          239 g          382 t
ORIGIN      
        1 gactagaaat ctaattaaaa ggggtgcttt ttttgcggaa atatacattt gtttttaaga
       61 aaaaagtagt ttcagactat ttaaataacg aaggcggcta caaatatctt gcacataaat
      121 atcaaataaa tcgtacactg gttagacatt gggtaaggat ttataactat catggttggg
      181 aaggcttggt tggaggtggc aaaagctaca ctacaaaatt taaacttgat gttatagaat
      241 atatggaaac aaatggtctt tctatccaag aaactgctaa aaaatttaat atcggttcaa
      301 atagaactct aagtaaatgg atagagcaat atgaagaagg cggtgcttct tcacttgaga
      361 gccaaaaaag gggcagaaaa attagtatga attccaagct aaacattcct aaaaaactta
      421 aagatgagtc tcttgaagaa gaagttattc gtttaagagc agagaacgca tatttaaaaa
      481 agttagaaac cttgattcaa gaacaagatt tgagcaagaa gaaatcaagg ttaaaacaat
      541 ccttcagctc aaaaaagaat ttaaattgaa tctattactt tcaattgcac aattagcgaa
      601 gtcaacttat tattactggg taaaaaaatt agataagcca gataaatata gcaagataaa
      661 gcaagaaatt acagcgattg taaaagaatc aagaaactct tatggttatc gtagagtcac
      721 tttagcgtta aagatgaaag gatatacaat caatcataaa acagttagaa aattaatgtc
      781 ccaaatggga cttacctgtc aaatccgaat aaagcgatat aaatcttata aaggaacagt
      841 aggaaaaatt gccaagaatg tgttaaaacg aaatttttca gtagatacac ccaataaaaa
      901 atgggtgaca gacgtcactg aattcaagat aaaaggaaga aaaatctatc tatctcctat
      961 acttgattta tttaacggag aaataattag ttatagtata tcaactagtc caacatataa
     1021 actgattgaa gaaatgcttc aacaagcaat taaaaaaaag ggaactgagg gttcactgat
     1081 tctacattca gatcaaggat ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga
     1141 gaataacatt attcaaagca tgtctagaaa aggaaattgc ttagataatt ctgtaataga
     1201 aaattttttt ggtgtgctta aatcagagtt tttttatcga gaaaaattcc gatcaattga
     1261 gatatttcaa agtaaattaa atgagtatat taggtggtat aataacaaaa ggataaaact
     1321 aaagttaaat ggactatctc cagtagaata tcggaaacag tccattaaat agtt
//
LOCUS       DBBGSP010000154         1368 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000154 DBBGSP010000000
VERSION     DBBGSP010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.165"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            82..>1368
                     /locus_tag="ACIZE9_003161"
     CDS             82..>1368
                     /locus_tag="ACIZE9_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HGC6094949.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIN"
BASE COUNT          467 a          263 c          257 g          381 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taatcaat
//
LOCUS       DBBGSP010000155         1321 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000155 DBBGSP010000000
VERSION     DBBGSP010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.166"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(372..445)
                     /locus_tag="ACIZE9_003162"
     tRNA            complement(372..445)
                     /locus_tag="ACIZE9_003162"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(409..411),aa:Ile,seq:cat)
     gene            complement(1000..1314)
                     /locus_tag="ACIZE9_003163"
     CDS             complement(1000..1314)
                     /locus_tag="ACIZE9_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094950.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          487 a          209 c          196 g          429 t
ORIGIN      
        1 actaattaac taccactcca attataagtc tttttcccat tattttttac agttatatgg
       61 tatgcttttt aatggcttca aatataaaag agtttaaagc gtaacacact tatggggaag
      121 tggtttttgg ggaacgcttt aaactcttct ttattattat ctcacaatat aacccaaatg
      181 tctttccatt taaaaatcaa agtaaaactt ttcaaatata cagaagtata actatgtgaa
      241 acatcctttc attaatccat aaaaggatac ataaaaaagc cactcatttg agtggcaatg
      301 aagaaaagct ttagcttgta taatactctt caaaaaattc taacacagaa cgattcaatt
      361 ggctacatta atgtaccctg taggactcga acctacgacc ggacggttat gagccgtctg
      421 ctctgaccaa ctgagctaag ggtagtggtt gttgccacat aaagccataa acaatcaacc
      481 agtagaatgc gtggcagcaa acctgttatc gcatatcttg gagtgtgact atttatgagt
      541 gatagtgaag atatgcgtct ccatatatgt atggttgaga cagataaaca tgtatgaaaa
      601 acgttgttaa atcaacgttt ttttattttg gtcaaggaga gaaaagtaga gaaatacaaa
      661 attttttgca ttgattttgc attcaaaaaa acattcaaac atttagaaat ccccaatacg
      721 tattcaggaa aatctatttt aaggtttaca aaaagaactt ttgttcgtac actctttttg
      781 aggtgaactt ttatgctgat ggaaggaaaa acacaattat ggtttaagca tgttccttca
      841 aataagtttt ttaattataa actctagaga aattaattca tcctaacata aaataattgt
      901 tcactcaaaa gtttttctag aacaattaaa acagcaggct tcacattcgc tatacatttg
      961 taagaagtaa taattcctgt actaaaaggc ataattgctt taattatttt ttgacttctc
     1021 ttcaaacaca agaagtagtt gtgtaataat tgcagaaata aggattccaa taatagatat
     1081 aaaatttgac atggaaacgt ctataacatt aaaagaataa agtgttgaag aaagtaaact
     1141 gattgaaata acccctccgt aaaaaatagt ctgtgaatat acccactttt tttcagaaga
     1201 cgtacttcgt ttggttctaa aacctatccc tgcatttcta ctcttatcaa aaaaccaaat
     1261 atttagaagt aataatattg ctattattaa gataaaatta ctgtaaaaat ccaaaagcta
     1321 t
//
LOCUS       DBBGSP010000156         1286 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000156 DBBGSP010000000
VERSION     DBBGSP010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.167"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(12..1151)
                     /locus_tag="ACIZE9_003164"
     CDS             complement(12..1151)
                     /locus_tag="ACIZE9_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HGC6094951.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT          335 a          281 c          239 g          431 t
ORIGIN      
        1 ttaaaaaaat cttacgctaa gtaggataaa ataattcctt gatatttttc gatcatatcc
       61 aaataattat cgatttcaac atactcatct acttgatgag gcaaagtaac gacaccaggc
      121 ccaaagacga caaagtcgaa ggaatggtta gctttcgtaa attcggctgc atccgttgtt
      181 gctgccgctc caactaaagg taatggctgg ctgaattgtt gctgaatgca atgaatcaaa
      241 ggagaatctg gatcagcttt gacaggtatt ttgttgtaat cgatcatcaa ttccaaatga
      301 tagtctgtct cttgattcaa ttcattgacg attgattgca gcaatgcaat gattttatca
      361 tttgggtatt ctggaatcga tcgaatgttc ccttggagct gcgcatggct tgggatgctg
      421 ttgacttgat tcccgccact gatcaatgta acattatgga ttgtttttcc taggacagga
      481 ttctcgattg tttcagcgag gtgattcatt tcagcatttg ctttcgtaat gaattcattt
      541 aggtgattga ttgcattata accttggtct ggcatagagc tatgcgcttc ttttccgtgc
      601 gaggtgactg tatagttgat tgatcccatg tgcgtataca tcaaactgta attggttggc
      661 tctccgatga tcaaggcatc taagtcatct acatagcctg ctttcgtgag ctgttcccca
      721 cctagttcac ccacttcttc tccgacagtg gctaataatt tgactgttcc gttaaatggt
      781 tttcctgact ctttcagttc gatcatggca atcaccattg ctgccaagcc actcttcata
      841 tctgtagcac cacgtccgta caaacggttc ccatggattt ctgctgcaaa gggtgcatag
      901 gtccaagacg attcatcacc agccgccacg acatccatat gcccagatag gcctaacact
      961 tttcctgatt ggcccttttg gtaacgagca atcaaattat ctctaccatc tctgtaagaa
     1021 acaatctctc ctgttatgtc atgctttgcc aaaagcttat tcaaataggc tgctacttca
     1081 ccttcgtttc cattcactga tttaattcgg ataatctctt gtaaaatcgc gattttttct
     1141 tcttttttca tctaatcctc tcccttgcca tttcttttta ttgtatttga gtgtgctcga
     1201 attttcaaat aggagcaacc aaagtaaaaa tgaagaaaga gagccacttt atgaaaaata
     1261 tgctgctact tccctcctat tttatt
//
LOCUS       DBBGSP010000157         1271 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000157 DBBGSP010000000
VERSION     DBBGSP010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.168"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            105..>1271
                     /locus_tag="ACIZE9_003165"
     CDS             105..>1271
                     /locus_tag="ACIZE9_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGC6094952.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSN"
BASE COUNT          408 a          257 c          239 g          367 t
ORIGIN      
        1 gatagaaaat cattctatcg gtcccttttg agcatgaaaa aacaaaacat acagaagctc
       61 cgttagaatt gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc
      121 atatcaaact actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga
      181 agagcattaa gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc
      241 gctgtccttt gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa
      301 aatcgctcat tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac
      361 aacgctacca ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata
      421 gaaactgctt tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac
      481 aagcaatgac gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac
      541 tcgcttctct gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa
      601 tggatgaatt tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg
      661 gcgatactgg aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt
      721 attttatgca atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga
      781 atgtttctta tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc
      841 gttttcacat tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga
      901 aaagctttga tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt
      961 ctcggcttct gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca
     1021 attttggttg ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg
     1081 acgaattacg aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag
     1141 aggcggacac tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc
     1201 attctataaa aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc
     1261 cttattcaaa t
//
LOCUS       DBBGSP010000158         1261 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000158 DBBGSP010000000
VERSION     DBBGSP010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.169"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(94..1137)
                     /locus_tag="ACIZE9_003166"
     CDS             complement(94..1137)
                     /locus_tag="ACIZE9_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HGC6094953.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
BASE COUNT          433 a          251 c          238 g          339 t
ORIGIN      
        1 tgttgttgtt agaaggatat ctgcaaaatt aaaaacagtt gtgattcgga cattgttcca
       61 tgcgagaatc acaactgttt tttcatgttc attctaaact ttgatcagcc aaataaatag
      121 taaagccatc actgtttgga gaagcccgac agctaatcca taagataaga agcgtgtacc
      181 ttctttcatg aattttgcaa agtctaaacg cagaccaatt gccgctaaag cagtgatctc
      241 aaaccagctg ctgataaaat gtgccgattg gtcaataact acaggtaaag aaaacaagct
      301 gttgaccaaa caaaagatca caaaccctaa tacataccaa ggaagcggta attttcgttt
      361 tttctgcgta tcagttggcg tttcaaacag agctggttgt ttcttgtgca tgaatttttc
      421 aaacagatag acaacaacaa cgagcatcat aatacgtaga atcttaaata gcatggcgaa
      481 ttcgacaaca gaattgtcaa gtaagcttgc cccagcgact acttgaccaa cagattggag
      541 tgtaccaccc aaaagtgcac ttttttcaat gagatttcca ccaaacaact gtaatccaag
      601 aaaagggaga gtcaacatca tcacagtacc cagtagattg actagtgtga tgatctgtcc
      661 tttttcttcc tctttcgcat ggatggaagg ggcgattgaa gcaatagcag aagaaccaca
      721 aacagcgttt cctccagcca tcatcaaaga agaagtatcg ctgaattgca gttttttacc
      781 aatcaagtaa gcaccgatga tagtgactga catttgcagt aacacaaaaa caattccttt
      841 tacaccaatt tgagcaatcg tttgagctgt gacagttgca cctagtaaaa aaacagagaa
      901 ttctaatagt ttgctttcag caaattttgt gccgattgct agaacaggct gtttaaaaaa
      961 agtatttcct aataaaatac ccaataaaat agcaatagtc gctccaccta actgtggcag
     1021 ataaatagca agaagcctgc tgaaggcagc gatggcaaaa gaaagcagta aaccgggtaa
     1081 gatttcgcgg accgctgaat cctttacaga ttttattgga tgtgacaatg atttcatttg
     1141 atcggttcct ttcgtcaata aatactaaaa gcatactcga acatagtagc actaaaccag
     1201 tattttgaca aaagaacaag aggtcgtgac aaaagtcttg tacgacctct tgtttcgaat
     1261 a
//
LOCUS       DBBGSP010000159         1246 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000159 DBBGSP010000000
VERSION     DBBGSP010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.170"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            200..742
                     /locus_tag="ACIZE9_003167"
     CDS             200..742
                     /locus_tag="ACIZE9_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094954.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="ACIZE9_003168"
     CDS             898..>1246
                     /locus_tag="ACIZE9_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HGC6094955.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DBBGSP010000160         1219 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000160 DBBGSP010000000
VERSION     DBBGSP010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.171"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            2..460
                     /locus_tag="ACIZE9_003169"
     CDS             2..460
                     /locus_tag="ACIZE9_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HGC6094956.1"
                     /translation="MLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTTLFVSV
                     IYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGLLPKFM
                     KVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            469..696
                     /locus_tag="ACIZE9_003170"
     CDS             469..696
                     /locus_tag="ACIZE9_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094957.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          377 a          195 c          204 g          443 t
ORIGIN      
        1 attgctatta aaatttgtcg ttttaggtat aagtgccgta tttattttgt tcggcgtact
       61 tttttatact cagatcgcta caagcgaaaa aggattcaat tttgattggc agaccacatt
      121 atttgtttct gtcatttact ttgcccttct cctagggatc gttattgctt atttcttatt
      181 gaaactattg aaaaaaatcg aagataacca agctttttcc actcaaagct taaacatact
      241 aaaaaaaatc gaacgaacca ttttgtttat tggtttcgcc ttttttggct tacttcctaa
      301 atttatgaaa gtagcggatt tagacgatgc tccaggtttg atgttggtag gaatcgctgt
      361 cgtattcatt ccttttgcag tatacacatt aacaagcgtg ctggaaaaac tgcttgaaca
      421 tgcgatttta cttaagacag atcatgattt gacagtgtga ggtgcgacat ggcaattatc
      481 gttaatttag atgtagtatt agctcaaaaa aaaatgagtg tgactgaatt gagtgagaaa
      541 gtgggcatta cgatggcaaa catctctatt ctaaaaaatg gaaaagcaaa agccatccgt
      601 ttttccactc tcgaaaaaat ctgccaagtt ttggagtgtc aaccaggtga tttgttgacc
      661 tataaaaatg actcgaatac tataccagaa gaataaaata aagtagaaca aacagtaaat
      721 aaaaaataat ctgaatgata gatgtgtgag acttttagaa gttatttacg tctattattc
      781 agatttttta tttcgattga ataccgtttt atctataaat aagatatgta ctgactcata
      841 caaagggggc cttttcttct ccatgtacta tcacttttcc tgatacaact ggtttcctgt
      901 tacgttgtag ttggatctgc ttttagtata atactttatt cattccacca gactgatagc
      961 agtttgagca gtctaaataa tcatgtagta ttacaggcca ttctgtttca taccttgaag
     1021 tgcttaaaac ttcagctaat ggcccattgt gttaactctt actccattct tttttagtaa
     1081 gctcccatat atactgtaaa gccttctata tattatgtca tgttgctttt taacatttac
     1141 tatgtagttt tgataaaatg atttgaataa cagtgatgga caattctttt ttatttttaa
     1201 cattattttg ataataatg
//
LOCUS       DBBGSP010000161         1203 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000161 DBBGSP010000000
VERSION     DBBGSP010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1203
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.172"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            414..947
                     /locus_tag="ACIZE9_003171"
     CDS             414..947
                     /locus_tag="ACIZE9_003171"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGC6094958.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT          386 a          221 c          224 g          372 t
ORIGIN      
        1 cttattaccg cagatgcaag cttttgaaca ccgtttattg agaagttgtg aaatcagcgt
       61 cctgacctga gtattagaga aacaaatggc aaaatagttc ctcatatttt gctatttttt
      121 gagctaatac cgagggtcag ctgattgaac accgtttagt ggagaagttg tgaaaaagtc
      181 gcctactttc gagtcgtaag aaattttttt gaaaatggtt cctcacaact ttgcataaat
      241 ttgacttaat accgagaagt catgatcccc atctaactcc aaatcacaag gaatgagttc
      301 aaaaactagc ttttctcaac aaatattaca taaaaaattc tatgtttttt gttaaattta
      361 tttgcttttt tcaaaagtat gttacagtaa tttcccaagg aggttttaca gaaatgaatt
      421 ttgttgccat ggattttgaa actgccaatc atcagcctta tagtgcttgt tctcttgcgc
      481 tagtcatggt aaaaaatagc cagatcgttg atgaattcta tacattgata cagcctgaga
      541 ctcctttttt ctggcgaaat gtccaaattc acggaatcca tcaagaagac gtacgcaatg
      601 cgccgaaatt cccagaagtc tggcaaacta tccaaccata ttttcaaaaa aatcgtttag
      661 tcgttgcaca taatgctgct tttgatacaa aggtcttagc gggatgctta gattattatc
      721 atcttgaaca gcctaattat ctttctttat gtacagtgaa aagtagccgt cgcctgtttc
      781 ctgaatttcc aaatcatcga ttgaacactg tgtgcgaaaa tttgaacatc caattagatc
      841 atcaccatga tgcattggaa gatagtcgtg catgtgcgga aatcctgctt tatcaagaaa
      901 aaaaattcgg gacagatcca ttgaaaaaac ttgtgactat aaagtaaaag aatacttatg
      961 aaacacacaa agaggtcgtg agcctgccgt ttcactccga gtcacaagga gcaatttcaa
     1021 aaaatagctt ctcatgttta ttaaatattg tgactggtga ccgaggagct ggcaggagaa
     1081 caccgtttat tggagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
     1141 acaaaaatag cttctcatat ttttcatttg gttggactta ttaccgcaga tgcaagcttt
     1201 tgg
//
LOCUS       DBBGSP010000162         1195 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000162 DBBGSP010000000
VERSION     DBBGSP010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.173"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..1076
                     /locus_tag="ACIZE9_003172"
     CDS             <1..1076
                     /locus_tag="ACIZE9_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HGC6094959.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DBBGSP010000163         1085 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000163 DBBGSP010000000
VERSION     DBBGSP010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.174"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            2..>1085
                     /locus_tag="ACIZE9_003173"
     rRNA            2..>1085
                     /locus_tag="ACIZE9_003173"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          332 a          215 c          318 g          220 t
ORIGIN      
        1 ataagggcgc acggtggatg ccttggcact aggagccgat gaaggacggg actaacaccg
       61 atatgctttg gggagctgta cgtaagctat gatccagaga tttccgaatg ggggaaccca
      121 acatctttaa taggatgtta cgattgtgtg aatacatagc acattcgagg tagacgcaga
      181 gaactgaaac atctaagtac ctgcaggaag agaaagaaaa ttcgattccc tgagtagcgg
      241 cgagcgaaac gggaaaagcc caaaccagca agcttgcttg ttggggttgt aggactccaa
      301 tatggtagtt ctttcagata gtcgaatgac ttggaaaagt cagtcaaaga gggtaaaaac
      361 cccgtagacg aaatgtggaa gacacctagg aggatcctga gtacggcgga acacgagaaa
      421 ttccgtcgga atccgggagg accatctccc aaggctaaat actccctagt gaccgatagt
      481 gaaccagtac cgtgagggaa aggtgaaaag caccccggaa ggggagtgaa atagaacctg
      541 aaaccgtgtg cctacaacaa gtcaaagccc gttaatgggt gatggcgtgc cttttgtaga
      601 atgaaccggc gagttacgat tgcatgcgag gttaagttga agagacggag ccgcagcgaa
      661 agcgagtctg aatagggcgt ttgagtatgt agtcgtagac ccgaaaccat gtgatctacc
      721 catgtccagg ttgaaggtgc ggtaaaacgc actggaggac cgaacccacg tacgttgaaa
      781 agtgcgggga tgaggtgtgg gtagcggaga aattccaaac gaacttggag atagctggtt
      841 ctctccgaaa tagctttagg gctagcctcg gaattgagaa tgatggaggt agagcactgt
      901 ttggactagg ggcccatctc gggttaccga attcagataa actccgaatg ccattcattc
      961 atatccggga gtcagactgt gagtgataag atccatagtc gaaagggaaa cagcccagac
     1021 caccagctaa ggtcccaaaa tatatgttaa gtggaaaagg atgtggggtt gcacagacaa
     1081 ctagg
//
LOCUS       DBBGSP010000164         1069 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000164 DBBGSP010000000
VERSION     DBBGSP010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.175"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..969
                     /locus_tag="ACIZE9_003174"
     CDS             <1..969
                     /locus_tag="ACIZE9_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HGC6094960.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          368 a          185 c          214 g          302 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
      901 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
      961 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
     1021 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccat
//
LOCUS       DBBGSP010000165         1069 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000165 DBBGSP010000000
VERSION     DBBGSP010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.176"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..919)
                     /locus_tag="ACIZE9_003175"
     CDS             complement(<1..919)
                     /locus_tag="ACIZE9_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC6094961.1"
                     /translation="MSKRGTIINEWENLTALSNRRLNVQNLNTPLKLQWSIDRITIVG
                     KLKENIYYHTQNDVLILDFEQLMRLNENNGYVKSVGLNGWQIVDKHDENIAYIEILKY
                     QEGQGRIDFNPNKINQFLASSMKNFIHDLFLEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKIVPKEIETWWRLELQ
                     LRRGKATDWHEMVHESLDSFASLHFLPIDTTPTDRIMLAGLMSDQNFWSLLSRNSKYK
                     YRELLKEESQNDELTNHLRETFAESADNLK"
BASE COUNT          344 a          220 c          153 g          352 t
ORIGIN      
        1 gtttcaaatt gtctgccgat tctgcaaacg tttctcgcaa atgattcgtc aattcatcat
       61 tttgactttc ttctttcagc aattcccgat atttatattt tgaattcctc gacaaaagag
      121 accagaaatt ttgatcagac attaaaccag cgagcattat tctatctgta ggtgttgtat
      181 caatcggcaa aaaatgcagg ctcgcaaaac tatccaaact ttcgtgaacc atttcatgcc
      241 aatcagtggc tttcccacgt cgcaactgca attctaaacg ccaccaagtt tcgatttctt
      301 tcggaacaat tttccgtttt ctttcttgtt ctaatttttt gttatacatc cgaatttgac
      361 gttcactagc acgactgccc caataagcag tttctaactt gccagaccga ccataaattg
      421 gtttaaacga tacaggatca accacccgat attgggtaat aaactcatca ggcacatcga
      481 taatatcgca agcaatatcc gcacgtgaaa aatgcggctc caaaaataaa tcatggataa
      541 aattcttcat agagctagct aaaaactgat taattttatt cggattaaag tcaattcgcc
      601 cttgaccttc ttgatatttc aaaatttcaa tgtaagcaat attctcatca tgcttatcca
      661 caatttgcca accatttaga ccaacagatt taacataacc attattttca ttcagtcgca
      721 ttaactgttc aaagtctaaa atcaatacat cattttgagt atgataataa atattttctt
      781 tcagttttcc aacaatggta attcggtcaa ttgaccactg taattttagg ggggtgttca
      841 aattttgaac atttaaccgc ctgttagata gggctgttaa attttcccac tcatttatga
      901 tcgtgccacg tttactcaaa ttttattcct cctcaaagaa aaagagactt ctggaaagaa
      961 ttttcaaaag ttcacgtaac tcttaaaaat tcattaccaa aaaatctcta gtcttgaaga
     1021 aatctaaaaa tattcgtata atgattaaga agttacggag ctagtgtga
//
LOCUS       DBBGSP010000166         1065 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000166 DBBGSP010000000
VERSION     DBBGSP010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.177"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            147..>1065
                     /locus_tag="ACIZE9_003176"
     CDS             147..>1065
                     /locus_tag="ACIZE9_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC6094962.1"
                     /translation="MSKKGIIVNEWEKLNRISNRRLSVDDKVHPLKLSWSIDRITIVG
                     KLNDTIAYWTQNGVVFVDFEQLMRLNENQGYLKSVGTNGWQLFDQYGEDIAYIEMLKF
                     HPDKGRIDFNPNKIGEFLKGSMKQFIHDLFLDAHFSRADIACDILGVPDDFITQYRIV
                     DPVSFKPIYGRSGKLETAYWGSRASERQVRMYNKKLEQERKKQIVPKEIETWWRIEMQ
                     LRRGKATDWHAMVRESLDSFASPHYLPGDVKPVDRIMIKGLNQDHSEWAYISRNLKYR
                     LRKLLKEESQNDELTNHLRETFKESANDLK"
BASE COUNT          345 a          162 c          242 g          316 t
ORIGIN      
        1 ttcacctagt tccgtaactc aagttcatta tacgaatatt tttaggtttc ttcaagctag
       61 agatttttgg atgtggattt ttagagttac gtgaactctg gaaattcttt ccaagaatct
      121 cttttttcgt tgaggaggag ctatttttga gtaaaaaagg cataatcgta aatgagtggg
      181 aaaaacttaa ccgtatttct aacaggcggt taagtgttga cgataaggta caccccctaa
      241 aattaagttg gtcaatcgat cgaattacaa tcgtcggaaa actgaatgat accatagctt
      301 attggacgca aaatggagtt gtgtttgtcg attttgagca attaatgcgt ttgaatgaaa
      361 atcaagggta tttgaagtcg gttggtacaa atggttggca attatttgac caatatggag
      421 aagatatcgc ctatatcgaa atgttaaaat ttcaccctga caaaggtcgt attgatttta
      481 atccaaataa aattggcgag tttttaaagg ggtcgatgaa acaattcatt catgatttgt
      541 ttctggatgc gcatttctca cgtgcagata ttgcttgcga tattctcggt gttcctgatg
      601 attttattac ccagtatcga atcgttgacc ctgtgtcttt taagccaatt tatggccgtt
      661 ctggcaaatt agaaacagcg tactggggta gtcgtgccag cgagcgacaa gtgcggatgt
      721 acaacaaaaa gcttgaacag gaacgaaaaa aacagattgt accaaaagaa atcgaaacat
      781 ggtggcgtat agaaatgcag ctaagacgtg gcaaagcaac agattggcat gcgatggttc
      841 gggaaagttt agatagcttt gcaagtcctc attacttgcc tggagatgta aaacctgttg
      901 atagaattat gataaaaggg ctgaatcaag atcattcaga gtgggcgtat attagcagaa
      961 atttgaaata tagattgcgc aaattgttga aagaagaaag ccaaaacgat gagttgacga
     1021 atcatttacg agagacgttt aaggaatctg caaacgactt gaaaa
//
LOCUS       DBBGSP010000167         1058 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.178, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000167 DBBGSP010000000
VERSION     DBBGSP010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.178"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(36..992)
                     /locus_tag="ACIZE9_003177"
     CDS             complement(36..992)
                     /locus_tag="ACIZE9_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094963.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgt
//
LOCUS       DBBGSP010000168         1052 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.179, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000168 DBBGSP010000000
VERSION     DBBGSP010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.179"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..963
                     /locus_tag="ACIZE9_003178"
     CDS             <1..963
                     /locus_tag="ACIZE9_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGC6094964.1"
                     /translation="PINGFAYTINNEFNLGANEGSSQVANNQYILLHETANETATGRN
                     EAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKA
                     TFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSE
                     MGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIE
                     NANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRADVNQAYNTSGNVGYHVS
                     FNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          363 a          190 c          213 g          286 t
ORIGIN      
        1 ccaattaacg gatttgccta tactatcaac aatgaattta atttgggcgc aaatgaaggt
       61 agctcacaag tagcaaataa tcagtatatt ttactgcatg aaacggctaa tgaaacagca
      121 acaggacgca atgaagcgca gtatatgcaa cgttcatgga ctagcgctta tactgcttat
      181 attgtgggag acggcggaat tgtttatcaa gtcggtcaac ctggttatgt acagtacggt
      241 gctggttcgt atgctaatgc caacagtcct gtgcagattg agttacaaca cacacatgat
      301 aaagcaacgt ttgagaaaaa ctacaaggca tacgttgaat tggctagaga ttcagcaatg
      361 aaatatggta ttccattaac gttggacact ccttataacc aaccgggaat caaatcgcat
      421 ttatgggtaa cacaaaacat ctggggcgat catacagatc cttacggtta tctttctgaa
      481 atgggcgtaa gtaaagaaaa attagcatat gatttagctc atggatttac cgatgaaaat
      541 ccaacaactt ctgaaaacaa gcctgtcatt gatccaacac gagctggtgc agctaatcct
      601 acactgacag atggaacgaa ttacgcccac attgatcagt ttggagaaat cgaaaatgca
      661 aatttgcatg tagctggatg gcacattgct aactataaat acgagtatat cttcattatg
      721 gattacaata ctgggaaaga attagctcga gtaagagctg atggaattta tagagcagat
      781 gtaaatcaag cttataatac ttctggaaat gttggctatc atgtatcttt taacatgcgt
      841 aacttcccta ataagaaagt ctatgtcatg atgcgggcaa cgaatgatcc agagggaaac
      901 actaaaggcg gtgcgcaaga tttccatgac aaacgttggt atttaaatat tcctaaacga
      961 taaaaatagc tcctcgttga ggagcattac ataactatat tgacaactat aaaaatcatt
     1021 cgataaaata gtgatgttat cgcatatctt ca
//
LOCUS       DBBGSP010000169         1045 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000169 DBBGSP010000000
VERSION     DBBGSP010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.180"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="ACIZE9_003179"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="ACIZE9_003179"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HGC6094965.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          376 a          132 c          182 g          355 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaac
//
LOCUS       DBBGSP010000170         1035 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000170 DBBGSP010000000
VERSION     DBBGSP010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.181"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..>1035)
                     /locus_tag="ACIZE9_003180"
     rRNA            complement(<1..>1035)
                     /locus_tag="ACIZE9_003180"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DBBGSP010000171         1024 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000171 DBBGSP010000000
VERSION     DBBGSP010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.182"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            281..973
                     /locus_tag="ACIZE9_003181"
     CDS             281..973
                     /locus_tag="ACIZE9_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGC6094966.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          441 a          145 c          170 g          268 t
ORIGIN      
        1 cgttttttgt aataaataca gtaatctatg aaatgaaaag ggttacgttt aataaaactt
       61 gcttttttgt ttttgttcac cataaatatt tatttaagaa agtattaacc tgcatttttc
      121 tctataaaaa agatttttta aatagataaa aaaggaggat taaatgagta tttgatagta
      181 tttatattaa aattacatat gtaatttaaa aacgcttgac attgtgtttg agatcactta
      241 cttttagcat gtaaaagtat tggattaagg agctatgcaa atgaaaaaga aatttattac
      301 tggtgggatt gtcgttgcat ttctatgtct aattggctac acaggcacgc ggtacgcaaa
      361 tgaaattatt ttgtggggtg gagagacaga tattgataca atcaatgaga atctgacaca
      421 gcttgatcat acattgacag ataaagagca agcgattaca gatcttaccg ctcgactagc
      481 acaaaaagaa cagacattgc aagattcaaa ggcagatgtc caagaatacc aaacaaaagt
      541 aaatgaatta gaaaaccaaa aaaatcaatc ggcagcagaa aaacaaaact tagaaagtca
      601 attagtcagc aaggatgcac aactacaaag caaacaaaat gaaatcaatg tcaaactaga
      661 tgagatcaac caaaaaaatg atgaaatcaa tcatctgaat gcagattgga cagcaagact
      721 acaagaagca caagcaaaac tttcagaatt acaaaatact gtaaatggtt tgaatcaaca
      781 aatcgcaaca ctgacacaag aaaaaacaaa tgtagaaact cagttaacag atacacaaaa
      841 gaaattagac gaagcaactg ctgaaaactc aagcttgaaa caatatattc aaaagttaga
      901 aaaagcaaaa gatgaagtgg aagatacagc tgataaatct cagcaaattg ttgaagaaca
      961 tttgcgtaaa taatctttct taacaagtaa acctaaatta gtaaagaagc aacagtaatc
     1021 tata
//
LOCUS       DBBGSP010000172         1001 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000172 DBBGSP010000000
VERSION     DBBGSP010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.183"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            369..1001
                     /locus_tag="ACIZE9_003182"
                     /pseudo
     CDS             369..1001
                     /locus_tag="ACIZE9_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          182 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac c
//
LOCUS       DBBGSP010000173          986 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000173 DBBGSP010000000
VERSION     DBBGSP010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.185"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..>986
                     /locus_tag="ACIZE9_003183"
     CDS             <1..>986
                     /locus_tag="ACIZE9_003183"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGC6094967.1"
                     /translation="EPGDFIMSGAGTIGRISRVPKQIKPGVFNQALIRLRINKEITDS
                     EYFIQFIRADFMQRKLTGANPGSAITNLVPMSEVKKWIVQFPILEEQKKIGNFFKQLD
                     DTIALQQRKLDLLKETKKGFLQKMFPKNGAKVPEIRFPGFTEDWEQRKFKEFSKKTGK
                     KNTKDLDFPAYSVSNKAGLISQTEQFDGSRLDDLEKTNYKFVEPNEFAYNPARVNVGS
                     IAFNNLGMTVIVSSLYVVVKMSEDLDNEFILQFIKSPTFIKEVKRNTEGSVREYLFYE
                     NFANIKFPFTRNKEEQQKIGAFFKQLDDTIALHQRKLDLLKETKKGFLQKMF"
BASE COUNT          375 a          159 c          189 g          263 t
ORIGIN      
        1 tagaaccagg cgattttatc atgagtggcg ctggaacaat tgggagaatt tcaagagtac
       61 caaagcaaat aaaaccgggt gtattcaatc aggctttgat tagacttaga ataaataaag
      121 aaatcacaga ttcagaatat tttattcaat ttattcgtgc agattttatg caaagaaaac
      181 tcacaggagc taatccaggt tcagcaatta caaatctcgt accaatgtca gaagtgaaaa
      241 aatggatagt acaatttcca atattagaag aacaaaagaa aattgggaac ttcttcaaac
      301 aactggacga cactatcgct cttcaacaac gtaagctaga tttattaaag gaaacgaaaa
      361 aaggattctt acaaaaaatg ttccctaaaa acggagcaaa agtgccagaa attcggtttc
      421 ctggatttac ggaagattgg gaacagcgta agttcaaaga gtttagtaag aagactggaa
      481 aaaagaacac gaaagattta gacttccctg cctattcggt aagtaataaa gcaggtttaa
      541 tttctcaaac agaacagttt gatggtagta ggttggatga tttagaaaaa acaaattata
      601 aattcgttga accaaatgaa ttcgcctata atccagcaag agtaaacgta ggatcaattg
      661 catttaacaa tcttggtatg acggtcattg ttagctctct ttatgtagtt gtgaaaatga
      721 gcgaggactt agataatgag ttcatacttc agtttatcaa gtcaccaaca tttatcaaag
      781 aggtcaagcg caacactgaa ggaagcgtac gagaatactt attctatgag aatttcgcta
      841 atatcaagtt tccttttact aggaataaag aggaacaaca aaaaatcggc gctttcttca
      901 aacaactcga cgacacgatc gctcttcatc aacgtaagtt agatttgctg aaggaaacga
      961 aaaaaggctt cttacaaaag atgttt
//
LOCUS       DBBGSP010000174          906 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000174 DBBGSP010000000
VERSION     DBBGSP010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.186"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..767
                     /locus_tag="ACIZE9_003184"
     CDS             <1..767
                     /locus_tag="ACIZE9_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HGC6094968.1"
                     /translation="IKVPKLKSLVRIKLHRQPKGIIKSATISRHSSGKYYISLLCKEE
                     IIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQRKLSRRALLAKN
                     KGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDIICIEDLNTKGML
                     RNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECGHKDGKKSLE
                     IREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          335 a          144 c          164 g          263 t
ORIGIN      
        1 tcatcaaagt tcctaaattg aagtcattag taagaattaa gcttcataga caaccaaaag
       61 ggattatcaa atctgctaca atatcacgtc attctagcgg taaatactat atttctttgt
      121 tgtgtaaaga agaaattatc gaattaccta aaactaattc cacaattggt attgacttag
      181 gtattatgga ctttgcgatt ctttctgatg gacaaaaaat tgataataat aaattcacgt
      241 ccaaaatgga aaagaaacta aagcgtgaac aacgcaaatt gtctaggcgt gctttattgg
      301 ctaaaaataa aggtaccaat ctatttgaag ctaaaaatta tcaaaaacaa aaacgcaaag
      361 tagctagatt gcatgaaaaa gtaatgaatc aacgtactga ttttctgaat aagttgagta
      421 cagaaatgat caaaaatcac gatattatct gtattgaaga cttaaacaca aaaggtatgt
      481 tgcgaaatca taaattagct aaaagtattt ctgatgtttc ttggtcaaag tttgtgacta
      541 aattacaata caaggctgac tggtatggac gaaaaatcat caaagtagat aaatggtttc
      601 cgtctagtca gatttgttca gagtgcggac ataaagatgg caagaaatct cttgaaattc
      661 gagaatggac ttgtcctgtt tgtcatactc atcatgatcg tgatatcaat gctagtatca
      721 atattctgac cgaaggtcta agactacatt ctatgggatt ggcttagatc caatcatcaa
      781 gaaccgtagg aactacgggg atagcttggt aaataagaga caccgctgtt agtaaagaaa
      841 tacgctatca agtatgctct attcccaaga agctcccact tcaagcgtta agaaccgtca
      901 ggttta
//
LOCUS       DBBGSP010000175          696 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000175 DBBGSP010000000
VERSION     DBBGSP010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.188"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(53..628)
                     /locus_tag="ACIZE9_003185"
     CDS             complement(53..628)
                     /locus_tag="ACIZE9_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HGC6094969.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          125 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaacg
//
LOCUS       DBBGSP010000176          662 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000176 DBBGSP010000000
VERSION     DBBGSP010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.189"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            122..457
                     /locus_tag="ACIZE9_003186"
                     /pseudo
     CDS             122..457
                     /locus_tag="ACIZE9_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            553..>662
                     /locus_tag="ACIZE9_003187"
     CDS             553..>662
                     /locus_tag="ACIZE9_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGC6094970.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELT"
BASE COUNT          234 a          127 c          132 g          169 t
ORIGIN      
        1 tttatataat aaaatgcaat acttttcgag agtgtaaaat attttgtgta aatagaaaaa
       61 aggaagtccc ttctgtagaa tagagttacc acaacacatt cacagaaaag aggacttcca
      121 tatgaacgat tttactacag aaattctaaa gactctagcg aacaaaggcg atttgaatga
      181 attattccgt gtccatttgg aaaaagctgt caatacgctt ctcaaaacgg agttaacggc
      241 tttcctcgat tacgaaaagt acgatcgcat tggttttaac acgggtaatt ctcgtaacgg
      301 ctcctatgac cgtacggtca agaccgagta cggggaactt catctccaga ttccgcgcga
      361 ccgcaacggc gagttcaagc aacagactgt tcctgcttat agacggacga atgatacctt
      421 agaggagacc gtcattcacc tcttccgaaa aggtatggat aggctacaat taactagtgg
      481 ataggctaca attaactaga cagaaaaatt aaggtgtgta gactagaaga aaacatacca
      541 ggaggaattt ttatgtctaa gagaacacga agaacttttt cacaagaatt caagcaacaa
      601 atcgtcaatc tttacttagc tggaaagcca cgtgtagaaa tcattcgaga atatgaacta
      661 ac
//
LOCUS       DBBGSP010000177          638 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000177 DBBGSP010000000
VERSION     DBBGSP010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.190"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
BASE COUNT          221 a           98 c          103 g          216 t
ORIGIN      
        1 gaagagtatt atacaagcta aagcttttct tcattgccac tcaaatgagt ggctttttta
       61 tgtatccttt tatggattaa tgaaaggatg tttcacatag ttatacttct gtatatttga
      121 aaagttttac tttgattttt aaatagaaag acatttgggt taaattgtga gataataata
      181 aagaagagtt taaagcgcac cccaaaccac ttccccataa gtgtgttacg ctttaaactc
      241 ttttatattt gaagccatta aaaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttacaattg gagtggtagt taattagtga cttatttttg attttatagc actgatacta
      361 taaaatatag atatcatcat attacacaat cttaatacta acttaaaaaa tatctccttt
      421 cacaagtatg gtgataaaat tcgttccggg ctaccttttt aggtagccta ctttaatctt
      481 tatacctttc tggatcaacg aaagtatact ttatatagtc ataacgccga tgatcgctac
      541 gtgcgtccgg cacgtcagtc atgaatcggc tacactagac tagacagaaa aaataaggtg
      601 tgtagaataa taaaaaacac actggaggat ttttcatg
//
LOCUS       DBBGSP010000178          625 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000178 DBBGSP010000000
VERSION     DBBGSP010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.191"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            1..625
                     /locus_tag="ACIZE9_003188"
                     /pseudo
     CDS             1..625
                     /locus_tag="ACIZE9_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          247 a          105 c          118 g          155 t
ORIGIN      
        1 gtaaagcaat ctaaaacgag tggttcattc aaagaaaaag ataatcttac gcctgaacaa
       61 aaagaattgt tagaactacg taaaagaaac cagcaattag aaatggaaaa tgatatttta
      121 aagcaagcag cgctgatatt cggacgaaga gacaagtaat cgatgcgaat aagcatcttt
      181 accctatatc agcgatgtgc agaatattag gtctatcacg tcagtcctat tattatcaat
      241 caaaaccaaa gaaagacgaa tcagaacttg aagaagtagt cgctgaagaa tttatccgca
      301 gccgaaaggc ctacggctca agaaaaataa aaaaagcctt atcaaaacga ggcattcaga
      361 tcagccgacg aaaaattagt agaatcatga aaaatagagg attaaaatcg agctatactg
      421 ttgcttattt taaagtacat cattctactt gcaatgaagc caaaacgaca aacgtattga
      481 atcgtaaatt cttaagagac aacccattag aagcgatcgt aacagacttg acttatgtac
      541 gagtcgggaa aaaatggaat tatgtctgtt tcattttgga tctgttcaat cgagaaattc
      601 tcggctattc ttgtggagaa cataa
//
LOCUS       DBBGSP010000179          576 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000179 DBBGSP010000000
VERSION     DBBGSP010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..576
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.192"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
BASE COUNT          186 a           81 c           81 g          228 t
ORIGIN      
        1 ttttttcttg atgtgatatc cttgtctttt ttgtaatgtt tttaacttat tgcttttgca
       61 aaatttattt acctgttttc tggatcaacg atagtgtaca ttatgctatc cttgtttgga
      121 ttttaggacg tttaaagagg cactttttta cataacttaa tccatagacc ttttaagcat
      181 gctgtgagat aataataaag aagagtttaa agcgcacccc aaaccacttc cccataagtg
      241 tattacgctt taaactcttt tatatttgaa ttcactaaga agcataccat atttttgaaa
      301 aaaagtgaga aaaaaggctt ataattagga tttagagtaa ttaattagat gtttatttta
      361 taggactgat actatagatt acaaatagta tcgtatttcg caatcttaaa attatcttct
      421 tactgtgaat aagataataa aatttgtatt tgtccttttt aggtaactta ttttaatcta
      481 tatacctttc tggatcaacg aaagtatact ttatatagtc ataacgccga tggtaactat
      541 gcactgtaac gataatgctg ctaaaatatc ttttta
//
LOCUS       DBBGSP010000180          556 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000180 DBBGSP010000000
VERSION     DBBGSP010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.193"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..>556
                     /locus_tag="ACIZE9_003189"
     CDS             <1..>556
                     /locus_tag="ACIZE9_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HGC6094971.1"
                     /translation="IDRFHIIKHMNQAFNELRIREMNELRKVGQKSQAEKLKKNWRFL
                     LKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAYPYFHELVEAFRD
                     KDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNGKIEAKNTHIKTM
                     KRVSYGFKSFENMRIRIFLINQLIK"
BASE COUNT          198 a          107 c          102 g          149 t
ORIGIN      
        1 gattgatcgg tttcatatta tcaaacacat gaatcaagcc tttaatgagt tgcgtatccg
       61 tgaaatgaat gaacttcgta aagtaggaca gaaaagtcag gcagaaaaac tgaaaaagaa
      121 ctggcgcttt ttgctaaaaa atcgtgcaaa catcaaccat tatgaataca aaacatggaa
      181 aagttttcga gcaccaaaat acccatttct tacggaagcg atgatgattg atcgattgct
      241 tggcttttct acgtccctga aggaggcgta tccctatttt catgaattag ttgaagcctt
      301 tcgagacaaa gaccctgact tatttttctc cttattggca gaacttcccg aaacgttaga
      361 tgacggcttt cgggaaaagc tccaaaacct tctgacctat gaagaaggca tcaccaacgc
      421 gatgatctat ccttacacca atggaaaaat agaagcgaag aatacccata taaagacaat
      481 gaaacgagta tcctacggat ttaaatcatt tgagaacatg agaattagaa tctttttgat
      541 caatcaatta atcaaa
//
LOCUS       DBBGSP010000181          528 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000181 DBBGSP010000000
VERSION     DBBGSP010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.194"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(5..90)
                     /locus_tag="ACIZE9_003190"
     tRNA            complement(5..90)
                     /locus_tag="ACIZE9_003190"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="ACIZE9_003191"
     tRNA            complement(107..178)
                     /locus_tag="ACIZE9_003191"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="ACIZE9_003192"
     tRNA            complement(190..262)
                     /locus_tag="ACIZE9_003192"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="ACIZE9_003193"
     tRNA            complement(280..361)
                     /locus_tag="ACIZE9_003193"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="ACIZE9_003194"
     tRNA            complement(369..441)
                     /locus_tag="ACIZE9_003194"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="ACIZE9_003195"
     tRNA            complement(445..517)
                     /locus_tag="ACIZE9_003195"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DBBGSP010000182          485 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000182 DBBGSP010000000
VERSION     DBBGSP010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.195"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..>485
                     /locus_tag="ACIZE9_003196"
     CDS             <1..>485
                     /locus_tag="ACIZE9_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HGC6094972.1"
                     /translation="DFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDYEK
                     YDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLETTI
                     IHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAIFM
                     DA"
BASE COUNT          176 a           88 c           81 g          140 t
ORIGIN      
        1 gattttacta cagaaattgt gcaaactcta gtcactaaag gcgatttaaa tgaattattc
       61 cgttcgcact tagaaaaagc gataaacaca ctcctacgga ctgaattaac ggctttttta
      121 gattacgaaa aatatgatcg cactggtttt aattcaggta attcgagaaa cggttcttac
      181 tttcgatcaa tcaaaaccga atatggtgaa ttaacattgg aaatacctag agatcgtaat
      241 ggtgagttta aacaacaaac tttaccagcc tacaaaagaa caaacgatac attggaaacc
      301 actattatcc atttattcga aaaaggtgtt acgatgtctg aaattgctga tttgatcgaa
      361 aaaatgtacg gtcatcacta tactccacaa accatgtcca acatgactaa agttctgact
      421 gaagaagtaa atgcctttaa atccagagcc ttaaatgata agtatgtcgc tatttttatg
      481 gacgc
//
LOCUS       DBBGSP010000183          477 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000183 DBBGSP010000000
VERSION     DBBGSP010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.196"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(71..>477)
                     /locus_tag="ACIZE9_003197"
     CDS             complement(71..>477)
                     /locus_tag="ACIZE9_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HGC6094973.1"
                     /translation="TPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATFTKMNA
                     ASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYRTYEDS
                     QITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          150 a           95 c           72 g          160 t
ORIGIN      
        1 cacgacctaa agatcgtgtc taattatgac tgtatcagaa aatatgatac caaacggatc
       61 tattcattaa ttaattgaca tagtttatct gttgctcttt tatgactgga taactgacca
      121 attcatgacg atccaagtct tctttattca tatttacagc agtaatttga ctgtcttcat
      181 acgtacgata ataataaatc cctttatcaa cgttacagca agaagaataa atcgtatatt
      241 cgtattttcc ttctccagta tcgcatactc ctttttgttg ctcgactgag cctagtatat
      301 gaaaaaattg actgatactt tcagattctg aatcacctga tgcagcattc attttagtaa
      361 atgtggcttt tacaaatcga gaaacagaag agagatctcc aggtaagccc aatcctccca
      421 tcccacgact ataaacattc aagctgatct ggtttgaaaa atgattttct ggtgttc
//
LOCUS       DBBGSP010000184          468 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000184 DBBGSP010000000
VERSION     DBBGSP010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.197"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..>468
                     /locus_tag="ACIZE9_003198"
     CDS             <1..>468
                     /locus_tag="ACIZE9_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HGC6094974.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          155 a           86 c           83 g          144 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaa
//
LOCUS       DBBGSP010000185          467 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000185 DBBGSP010000000
VERSION     DBBGSP010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.198"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..>467
                     /locus_tag="ACIZE9_003199"
     CDS             <1..>467
                     /locus_tag="ACIZE9_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HGC6094975.1"
                     /translation="FGHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIET
                     ALNQWFSRFPKNFFKSITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNG
                     ILRRNGLPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAF"
BASE COUNT          156 a           89 c           79 g          143 t
ORIGIN      
        1 agtttggtca ccttgaaggt gatacgatcg ttggcattca tcataaaagt gccgtcatta
       61 ctttagttga aagattatct aaagtcatta tcacgattaa acccaacggc cgtaaggcat
      121 tagatattga aactgccctt aatcaatggt tttctcgctt ccctaaaaac ttctttaaat
      181 ctattacgtt tgactgtgga aaagaatttt ctaactggaa agccattagt aaccaacatg
      241 atattgatat atattttgcg gaccctggaa caccttctca acgcccatta aacgagaatt
      301 ctaacgggat tctgcgtcgt aatggactgc cgaaatcaat ggattttaga aaagtgaatc
      361 agacatttat ttccagtgtc agcaatcaac gtaatcatat tccaagaaaa tcattgaatt
      421 acagaacacc aatcgaaata tttttgagct atgtacaaga agcattt
//
LOCUS       DBBGSP010000186          460 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000186 DBBGSP010000000
VERSION     DBBGSP010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.199"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(20..91)
                     /locus_tag="ACIZE9_003200"
     tRNA            complement(20..91)
                     /locus_tag="ACIZE9_003200"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="ACIZE9_003201"
     tRNA            complement(113..200)
                     /locus_tag="ACIZE9_003201"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="ACIZE9_003202"
     tRNA            complement(225..298)
                     /locus_tag="ACIZE9_003202"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="ACIZE9_003203"
     tRNA            complement(312..382)
                     /locus_tag="ACIZE9_003203"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="ACIZE9_003204"
     tRNA            complement(384..459)
                     /locus_tag="ACIZE9_003204"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DBBGSP010000187          457 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000187 DBBGSP010000000
VERSION     DBBGSP010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.200"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..>457
                     /locus_tag="ACIZE9_003205"
     CDS             <1..>457
                     /locus_tag="ACIZE9_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6094976.1"
                     /translation="VQGWTPDVIVGRAAFPISCSARTIYRMFKKGLFDSSDLPMKGKR
                     KPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHLEGDTIVGLKHKSAVITLVERLSK
                     VIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSITFDCGKEFSNWKQISN"
BASE COUNT          151 a           78 c           94 g          134 t
ORIGIN      
        1 gttcaaggat ggacacccga tgtgattgtt ggtcgtgcag cgtttcctat tagttgttct
       61 gctcgtacca tttatcgtat gttcaaaaag gggctatttg attcttctga cttaccgatg
      121 aaaggcaagc gtaaaccgaa tggacatcaa gaaagacgtg gaaaacaaac tttccgccgc
      181 tctattcatg aacgtgaaaa ggattatagc caattctcaa atgagtttgg tcaccttgaa
      241 ggtgacacta tcgtaggtct gaaacataaa agtgctgtaa ttaccttagt tgaacgatta
      301 tcaaaagtta tcatcacatt gaaaccgtgt ggtagacaag cgattgatat tgaaaaaaaa
      361 ttaaatcaat ggtttgaatc tgtaccgaaa aacctattca aatccatcac ttttgattgt
      421 ggaaaggaat tttcaaattg gaaacagatc agtaatg
//
LOCUS       DBBGSP010000188          427 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000188 DBBGSP010000000
VERSION     DBBGSP010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.201"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            76..>427
                     /locus_tag="ACIZE9_003206"
     CDS             76..>427
                     /locus_tag="ACIZE9_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6094977.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIF"
BASE COUNT          164 a           68 c           80 g          115 t
ORIGIN      
        1 agaaaaataa aaaggcattt atggtacact caaattgtat ttccgacgaa agaaaacaaa
       61 ggagtgtaac cataaatgac ctacaaacat cttaccatag acgaactgac aatgatagaa
      121 tcatattatc ttcaacataa taagccggtt gaaatcgcta accgaatggg acgtgctata
      181 caaactattt ataatgtagt caataagttc aagcaaggca agactgctct tgattattgg
      241 caccagtata aagaaaataa gaaaaaatgt ggtagaaaag tcattcaatt acctgctcat
      301 gaagtagatt acattaaaga gaaagtcact cttggttgga cgcctgacgt cattatcggg
      361 cgaaaagaaa ggtctgtttc atgcggtatg agaacacttt atcgtttatt ttctaaagga
      421 atatttg
//
LOCUS       DBBGSP010000189          421 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000189 DBBGSP010000000
VERSION     DBBGSP010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.202"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..390
                     /locus_tag="ACIZE9_003207"
     CDS             <1..390
                     /locus_tag="ACIZE9_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC6094978.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          163 a           74 c           65 g          119 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
      301 tttgatacat acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaacc
      361 gatacattag tttcaatgtt tactgagtaa ctaattattt tgcaggagga caatttattt
      421 a
//
LOCUS       DBBGSP010000190          415 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.203, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000190 DBBGSP010000000
VERSION     DBBGSP010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.203"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..339)
                     /locus_tag="ACIZE9_003208"
     CDS             complement(<1..339)
                     /locus_tag="ACIZE9_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094979.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DBBGSP010000191          396 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000191 DBBGSP010000000
VERSION     DBBGSP010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.204"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(91..>396)
                     /locus_tag="ACIZE9_003209"
     CDS             complement(91..>396)
                     /locus_tag="ACIZE9_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGC6094980.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          107 a           95 c           78 g          116 t
ORIGIN      
        1 ttgtgaatgc tgcggtgtta tggctacgat tgcccttgac aatgagcatc ctcggatctg
       61 attttctccg gcagaagcac aatcattcaa ttacgctgcc tctccagagg tatcagatcc
      121 gcgctcatta tcaaggattc gcttcgccaa tctctgttgt cgaatttgga tcggtgtttc
      181 atacgccaac gtgccatgta agcgtagata gttccaccaa tgcacataat caaacaattc
      241 tagacgtagc tgtgccagtg tctcaaattg gtattgatgc acgaattcta ctttgacaga
      301 tttataggtt gattccacaa cggcattatc atacggacaa cccttcctac tcaatgaacg
      361 agtaattcca aaaccattca gaatctcatg aatggt
//
LOCUS       DBBGSP010000192          381 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000192 DBBGSP010000000
VERSION     DBBGSP010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.205"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(21..94)
                     /locus_tag="ACIZE9_003210"
     tRNA            complement(21..94)
                     /locus_tag="ACIZE9_003210"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="ACIZE9_003211"
     tRNA            complement(108..181)
                     /locus_tag="ACIZE9_003211"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="ACIZE9_003212"
     tRNA            complement(209..281)
                     /locus_tag="ACIZE9_003212"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="ACIZE9_003213"
     tRNA            complement(301..374)
                     /locus_tag="ACIZE9_003213"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
BASE COUNT          103 a          108 c           90 g           80 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat t
//
LOCUS       DBBGSP010000193          375 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.206, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000193 DBBGSP010000000
VERSION     DBBGSP010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.206"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..132)
                     /locus_tag="ACIZE9_003214"
     CDS             complement(<1..132)
                     /locus_tag="ACIZE9_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HGC6094981.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          132 a           69 c           76 g           98 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaat
//
LOCUS       DBBGSP010000194          341 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000194 DBBGSP010000000
VERSION     DBBGSP010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.207"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..>341
                     /locus_tag="ACIZE9_003215"
     CDS             <1..>341
                     /locus_tag="ACIZE9_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HGC6094982.1"
                     /translation="EATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEP
                     DAFEGIKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNR
                     SDADKYEPTVEG"
BASE COUNT          141 a           50 c           76 g           74 t
ORIGIN      
        1 gaagcaactc aaccaattac agcagatgat acagaatttg tatcaagtgc aacaaaactg
       61 gatgataaat ctgacgctga caaatataat cctgaaggtc aaaaagtgac tacagaattg
      121 aataaggaac cagacgcatt tgagggaatt aagaacaaag aagatttacc aaaagatact
      181 aagtatactt ggaaagaaaa agtagatgtt agcgcagctg gaaataaaaa agggactgtt
      241 gtagtgacat atccagatgg atcatctgat gaagttgaag tagatgttac agtgacagac
      301 aatcgttctg acgccgataa atatgagcca acagtagaag g
//
LOCUS       DBBGSP010000195          329 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000195 DBBGSP010000000
VERSION     DBBGSP010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.208"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            37..>329
                     /locus_tag="ACIZE9_003216"
     CDS             37..>329
                     /locus_tag="ACIZE9_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008177227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC6094983.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYSF"
BASE COUNT           94 a           65 c           65 g          105 t
ORIGIN      
        1 atagatttat gaaaacgaat gcaaggagtg atagctatga tgtctaaaaa caatacgaat
       61 ggtagaaatc aatttgcgat gcttacgatt gatgatctag ttcctcaaga tcatctcgtt
      121 cgaaagattg atgccgcgct tgattttgaa tttatttatc caatcgtcga agccacttac
      181 tccgatttag gtcgcccaag tatcgatcca gtgattctga tcaaattggt gtttattcag
      241 tatttattcg gtatccgttc catgcgacaa accattaagg aagtcgatac caatgtcgct
      301 taccgctggt tcttaggcta ctccttcga
//
LOCUS       DBBGSP010000196          323 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000196 DBBGSP010000000
VERSION     DBBGSP010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.209"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACIZE9_003217"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACIZE9_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HGC6094984.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT          100 a           49 c           51 g          123 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatatc aactcatttc ttg
//
LOCUS       DBBGSP010000197          321 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.210, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000197 DBBGSP010000000
VERSION     DBBGSP010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.210"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..>321)
                     /locus_tag="ACIZE9_003218"
     CDS             complement(<1..>321)
                     /locus_tag="ACIZE9_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC6094985.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSL"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DBBGSP010000198          293 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000198 DBBGSP010000000
VERSION     DBBGSP010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.211"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            87..>293
                     /locus_tag="ACIZE9_003219"
     CDS             87..>293
                     /locus_tag="ACIZE9_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGC6094986.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIY"
BASE COUNT           92 a           60 c           45 g           96 t
ORIGIN      
        1 tttacctatg aaatattttc acgtgttaaa gtattcctcg ttgaacacaa caaataaaac
       61 tttttaacga ataaaggaga tttttcatga catcacttaa aactttactt tttggaacaa
      121 ctttggctgc cggcgctgca ttcttcatgg gaacgactgc tcatgcggac gaagcttata
      181 ccgttcaatc aggtgatact ctatcaacga tttctcaaaa atacgttggt gataactcct
      241 tgatcaatgc cattgcagaa tcaaattcaa tttctgatat taacctgatc tac
//
LOCUS       DBBGSP010000199          291 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.212, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000199 DBBGSP010000000
VERSION     DBBGSP010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.212"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..>291
                     /locus_tag="ACIZE9_003220"
     CDS             <1..>291
                     /locus_tag="ACIZE9_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGC6094987.1"
                     /translation="LVKQSKRLFPEINCVVADAGYKTPKFVHFLTHLNLRPCLPYSRP
                     KGKKGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKECVNC"
BASE COUNT           86 a           55 c           58 g           92 t
ORIGIN      
        1 agctcgtcaa acaatcgaag agactttttc ctgaaatcaa ttgtgttgtc gctgatgctg
       61 ggtataagac acctaagttt gttcactttt tgactcattt gaaccttcga ccttgtttgc
      121 cttattcaag gcccaaaggg aaaaaggggc tattatcaaa aaatgagttt ctctatgacg
      181 agtattttga ttgttatatt tgtccgcaag atcaaatgct cgctttttca acggttactc
      241 gagaagggta ccgagaatac aaatccaatc caaaagaatg tgtgaactgt c
//
LOCUS       DBBGSP010000200          285 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.213, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000200 DBBGSP010000000
VERSION     DBBGSP010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.213"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..>285
                     /locus_tag="ACIZE9_003221"
     CDS             <1..>285
                     /locus_tag="ACIZE9_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6094988.1"
                     /translation="HHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQSVPKN
                     LFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRK"
BASE COUNT           99 a           60 c           50 g           76 t
ORIGIN      
        1 ccaccataaa agtgccgtca tcacactcgt tgagcgactt tcaaaagcca ttatcgcctt
       61 gaaaccagaa ggccgtaagg cagttgatat tgaaaattcg attaatgaat ggcttcaatc
      121 cgtacccaaa aatcttttca aatcaattac ctttgattgt ggaaaagaat tctctaattg
      181 gaaaagtatt agtaatacga atgatattga tatttatttc gcagacccag gaacgccttc
      241 ccaacgggga ttaaatgaac attcaaacgg actcctccga aaaga
//
LOCUS       DBBGSP010000201          281 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.214, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000201 DBBGSP010000000
VERSION     DBBGSP010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.214"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            1..281
                     /locus_tag="ACIZE9_003222"
                     /pseudo
     CDS             1..281
                     /locus_tag="ACIZE9_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          111 a           56 c           54 g           60 t
ORIGIN      
        1 aaacaacaaa tcgtcgatct ctatctcgct ggtaagcctc gcgcagaaat tattcgagag
       61 tatgagctta cgccttcttc tttcgataaa tggatgaagc aagcacaatc aacgggctca
      121 ttcaaagaaa gagacaactt aacaccagaa caagcagaat tgatcgcact aagaaagaaa
      181 aataagcaac tcgaaatgga gaatgatatt ttaaagcaag cggcgctgat attcggacga
      241 aaagacaagt aattgatgcc aacaagcata aatattccat a
//
LOCUS       DBBGSP010000202          281 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.215, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000202 DBBGSP010000000
VERSION     DBBGSP010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.215"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(97..>281)
                     /locus_tag="ACIZE9_003223"
     CDS             complement(97..>281)
                     /locus_tag="ACIZE9_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6094989.1"
                     /translation="RQHCSTIFLLFFLIFFDYSTPLEKIKRPQGISFPEPLEPPPAEI
                     EWRCQHLFRSAIGYTI"
BASE COUNT           86 a           42 c           81 g           72 t
ORIGIN      
        1 tagcgtttat ttcgtttagt tatcggcaca atcggtgaaa cacgttagag gagcgaaaat
       61 ggagcctgta aggcgactgg tagcggaacg gtcgtgttag attgtgtagc cgatagctga
      121 acgaaataaa tgctggcagc gccattctat ttcggcagga ggaggctcaa ggggttcggg
      181 gaatgaaatt ccctgaggtc tttttatttt ttctagagga gtgctataat caaagaaaat
      241 gagaaaaaag agtaaaaaaa tagtcgagca gtgttgacgc a
//
LOCUS       DBBGSP010000203          267 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000203 DBBGSP010000000
VERSION     DBBGSP010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.216"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(35..>267)
                     /locus_tag="ACIZE9_003224"
     CDS             complement(35..>267)
                     /locus_tag="ACIZE9_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC6094990.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           78 a           39 c           47 g          103 t
ORIGIN      
        1 tagaaggact gaccttctgt ctcagatttt tttgttattt cacttgaatc aattgattga
       61 tcaaaaaaat cctgattttc atgttctcaa atgatttaaa tccataagat aatcgtttca
      121 gtgtcttgat atggggaatc ttggcctcta ttttgccatt agaatacggg taaatcatag
      181 cattgtaaat accttcttca tacgttaaaa ggttttgaag tttcgtgcga agttgtgcat
      241 caagtgtttc aggaagattt tttaata
//
LOCUS       DBBGSP010000204          260 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.217, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000204 DBBGSP010000000
VERSION     DBBGSP010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..260
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.217"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..220)
                     /locus_tag="ACIZE9_003225"
     CDS             complement(<1..220)
                     /locus_tag="ACIZE9_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6094991.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLE"
BASE COUNT           64 a           49 c           47 g          100 t
ORIGIN      
        1 cttctaaagt tccccattta atccagtcaa ttgttgaatt agtgatagtt gataataatt
       61 tcagcttttg tggatttggt aaattggtcc cacgttccca gttggatatg gtcgcacgtg
      121 gtgaattatc tattttcctt ccaagttctt ccatagtaaa accacatgaa aggcgtaatt
      181 gtttgattcg ttttcctgct tctgaaggat ttggcttcat acaatcacct ctcttatgga
      241 atttgggtta cttcaaattc
//
LOCUS       DBBGSP010000205          253 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.218, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000205 DBBGSP010000000
VERSION     DBBGSP010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.218"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..>253
                     /locus_tag="ACIZE9_003226"
     CDS             <1..>253
                     /locus_tag="ACIZE9_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HGC6094992.1"
                     /translation="GFTKQSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSY
                     PLVGPATWDGKVYVQNLFNAAGIKEPITSLDAQVRLLIWT"
BASE COUNT           80 a           40 c           58 g           75 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga cat
//
LOCUS       DBBGSP010000206          247 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.219, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000206 DBBGSP010000000
VERSION     DBBGSP010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.219"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..>247
                     /locus_tag="ACIZE9_003227"
     CDS             <1..>247
                     /locus_tag="ACIZE9_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGC6094993.1"
                     /translation="PIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAKRGLQLSRRRI
                     GRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTF"
BASE COUNT           80 a           51 c           61 g           55 t
ORIGIN      
        1 ccgatcgaaa atgagtccga cttagaagag atcgttcagg aagagtttat tcgaaaccga
       61 aaggcttacg gtacccgaaa attgaagaag tgtttagcaa agcgtgggct tcaactcagt
      121 cggcgccgaa tcggtcgaat catgaaacgc cgcggattga catctaccta tacgatcgct
      181 cattttaaag ggcaacgaac agcttgtaat gaagcgaaaa cagcgaatgt attagatcgg
      241 accttta
//
LOCUS       DBBGSP010000207          241 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.220, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000207 DBBGSP010000000
VERSION     DBBGSP010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.220"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..220)
                     /locus_tag="ACIZE9_003228"
     CDS             complement(<1..220)
                     /locus_tag="ACIZE9_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC6094994.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFP"
BASE COUNT           63 a           45 c           46 g           87 t
ORIGIN      
        1 caggaaaaat gatttcggtt ctcccacaac gtcgcttatt ttctttgtat tgttcaaagt
       61 attcaagtgc tgttccacca catttgagaa agttatagac attgtaaatt gtttggcgtc
      121 cacgtttaag ctgcttcgca acgatagcaa ccggagtttc ttgatgaaaa tatgcttcta
      181 tcattacaag ctcgtttggt gtaagatggg tataagtcat ttatgttcac tctccttgta
      241 t
//
LOCUS       DBBGSP010000208          234 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.221, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000208 DBBGSP010000000
VERSION     DBBGSP010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.221"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..>234
                     /locus_tag="ACIZE9_003229"
     CDS             <1..>234
                     /locus_tag="ACIZE9_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HGC6094995.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAA
                     ESQTPAKPAAEPTVDTESAGSSSEGVFQFKLPDI"
BASE COUNT           73 a           50 c           60 g           51 t
ORIGIN      
        1 ccgtcacctg ttacaggaac ggttaaaaat gtgattgttc cagaaggtac cgtagcaaat
       61 gttggggatg tattagtaga aatcgatgca ccaggacacg aagacaatga aggggacagt
      121 ggtgtagccg cagaatccca aactccagct aaaccggctg ctgaacccac tgttgataca
      181 gaatcagctg gatcgtcaag cgaaggagtc ttccaattta agttaccgga tatc
//
LOCUS       DBBGSP010000209          233 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.222, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000209 DBBGSP010000000
VERSION     DBBGSP010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.222"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
BASE COUNT           77 a           44 c           36 g           76 t
ORIGIN      
        1 cgttttttca tccattcctt tcttcccccc ttacaaataa ataataacct ttaacaacca
       61 actcgtaaat aggttggttg ttattataca aaaggatatt agtactcaga taaaaagttg
      121 ttagtactca gataaaaagt tgttagtact cagataaaaa gttgttagta ctcagataaa
      181 aagttgttag tacccttctg tatccgttgg gagagtaagg ctcaactgcc ccc
//
LOCUS       DBBGSP010000210          231 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.223, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000210 DBBGSP010000000
VERSION     DBBGSP010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.223"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
BASE COUNT           79 a           35 c           44 g           73 t
ORIGIN      
        1 agaaaaagca tggaatgcgc tgcatcaggt atcgaggctt agaaaaaaat caggtgcata
       61 cgatgcttgt ttttgccgaa atgagtctga aaaaattggt cacttagcag tgggagcata
      121 tgtcttcata ttttttatta tacaaaaata gacaaaagta tcagtctaca ctcttagtaa
      181 agaggaaact gatacttttg tctacagtat gatatttctt acatctactt t
//
LOCUS       DBBGSP010000211          230 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.224, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000211 DBBGSP010000000
VERSION     DBBGSP010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.224"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
BASE COUNT           67 a           56 c           35 g           72 t
ORIGIN      
        1 tactctttga caaagagtaa cattttccta attgtgacat ggctgtcaca attccaaatg
       61 ctctccgagg gtattcgctg tcacaagtga caacgaaaaa aggagccgaa agcgtgtcac
      121 gctctcaact ccttttacgc tttattttgc ttcacgcaaa ataatcgctt atcgtaaact
      181 cacgtcatta aacattgacg taaatttact ctcactcatc tgacttttct
//
LOCUS       DBBGSP010000212          230 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.225, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000212 DBBGSP010000000
VERSION     DBBGSP010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.225"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..>230)
                     /locus_tag="ACIZE9_003230"
     CDS             complement(<1..>230)
                     /locus_tag="ACIZE9_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGC6094996.1"
                     /translation="AFSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHK
                     GCPFDNAVAESTYKSLKVEFVYQYTFETLQQL"
BASE COUNT           73 a           40 c           39 g           78 t
ORIGIN      
        1 tccaattgtt gtaaggtttc aaatgtgtat tgatagacaa attctacttt caacgactta
       61 taagttgatt cagctacggc attatcaaaa ggacagcctt tatgactcaa tgatcgattg
      121 atgtcaaaag ttgttaataa ttcatcaata gcttggttat caaactcttt tccacgatca
      181 gtatgaaaaa tctcaacctc tgtcagaggt tgtttgatac ggctaaatgc
//
LOCUS       DBBGSP010000213          220 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.denovo.226, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000213 DBBGSP010000000
VERSION     DBBGSP010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.denovo.226"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..175)
                     /locus_tag="ACIZE9_003231"
     rRNA            complement(<1..175)
                     /locus_tag="ACIZE9_003231"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           48 a           60 c           49 g           63 t
ORIGIN      
        1 cctgtttcca agtgttatcc ccttctgatg ggcaggttac ccacgtgtta ctcacccgtt
       61 cgccactcct ctttttccgg tggagcaagc tccggtggaa aaagaagcgt tcgacttgca
      121 tgtattaggc acgccgccag cgttcgtcct gagccaggat caaactctca taaaaagttc
      181 gaacaatctt gcgattgtta agctcaattt gtttgctagc
//
LOCUS       DBBGSP010000214         6796 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.guided.101, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000214 DBBGSP010000000
VERSION     DBBGSP010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.guided.101"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..171
                     /locus_tag="ACIZE9_003232"
     CDS             <1..171
                     /locus_tag="ACIZE9_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HGC6094997.1"
                     /translation="EVRDKRAKDLGRVVELAAFTSPPPKERFKMKKADNKMPVDPFER
                     AEYLYSLIESEE"
     gene            191..1735
                     /locus_tag="ACIZE9_003233"
     CDS             191..1735
                     /locus_tag="ACIZE9_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC6094998.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            1878..2102
                     /locus_tag="ACIZE9_003234"
     CDS             1878..2102
                     /locus_tag="ACIZE9_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC6094999.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            2117..2986
                     /locus_tag="ACIZE9_003235"
     CDS             2117..2986
                     /locus_tag="ACIZE9_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HGC6095000.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            2967..3701
                     /locus_tag="ACIZE9_003236"
     CDS             2967..3701
                     /locus_tag="ACIZE9_003236"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC6095001.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            3734..4642
                     /locus_tag="ACIZE9_003237"
     CDS             3734..4642
                     /locus_tag="ACIZE9_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HGC6095002.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            4639..5181
                     /gene="sat4"
                     /locus_tag="ACIZE9_003238"
     CDS             4639..5181
                     /gene="sat4"
                     /locus_tag="ACIZE9_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HGC6095003.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5274..6068
                     /locus_tag="ACIZE9_003239"
                     /note="aph(3')-IIIa"
     CDS             5274..6068
                     /locus_tag="ACIZE9_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HGC6095004.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            6344..>6796
                     /locus_tag="ACIZE9_003240"
     CDS             6344..>6796
                     /locus_tag="ACIZE9_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC6095005.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNK"
BASE COUNT         2347 a         1070 c         1547 g         1832 t
ORIGIN      
        1 gaagttagag ataaacgtgc aaaggattta ggacgagtgg tagagcttgc cgctttcacc
       61 tctccccctc ccaaagaacg attcaaaatg aaaaaggcag ataataagat gccagtggat
      121 ccttttgaac gagcagaata cttatacagt ctgatagaaa gcgaggaata aagtgacaga
      181 gaaaaatata atggttattc ctgctcgtaa aagagtagga agtacagccg caaaagaaaa
      241 gataaagaaa cttcgtgttg ctgcctattg ccgtgtttct acagaaacag aagaacaaaa
      301 ttctagctat gaggttcagg tctcacacta tacagagttt ataaagaaaa ataatgaatg
      361 ggagtttgct ggcatctttg cagatgatgg tatctctggt acgaacacta aaaagcgtga
      421 cgaatttaat cgcatgattg cagagtgtat ggacggtaac atcgacatgg ttattacaaa
      481 atccatcagc cgatttgcgc gtaacaccct agactgcctt caatacatta gacagctcaa
      541 ggataagaac atatcagttt attttgagaa agagaacatc aacaccacgg atgccaaagg
      601 tgaggttttg ctgactatta tggcatcttt ggcacagcag gaaagccaga gcctttcaca
      661 aaacgttaag cttgggctac agtaccgata ccaacaagga aaggtgcagg tcaaccataa
      721 gcgatttatg ggctacacga aagatgaaga tggaaattta actattgtcc ccgaagaagc
      781 tgagattatc aaacgcatct accgagaata ccttgagggt cagagtctag tgggcattgg
      841 tcgagccctt gaaaaggatg gtattttaac agcagcggga aaaccaagat ggcgaccaga
      901 atcagttaag aagatacttc aaaacgaaaa atacatcgga gatgcccttc tgcaaaagac
      961 tgtcacagta gattttctga ccaagaaacg agtgaaaaat gaagggcatg ttccccaata
     1021 ttatgttgaa aatagccatg aagcgattat tcctaaagag ttatttttgc aggcgcaaga
     1081 agaaattcat cggagaagca atatctacac aggagaaggc aagaacaaaa gaatttacag
     1141 tagcaagtac gctttaagtg ccatcacctt ctgtggagat tgtggcgata tttatagacg
     1201 ggtctattgg aatatccacg gaagaaaaga atttgtctgg cgatgcgtga ctagaatcga
     1261 gcaaggtcct gaagtttgta agaaccgaac cgtaaaagaa gatgaacttt atggtgcagt
     1321 aatgactgcg attaataagc tacttgcagg tgggaacaat atgataaaga cactggaaga
     1381 gaatattcat gctgtgattg gcgaaaccac agaataccaa atttcagaga ttaacaactc
     1441 actagaggaa aaacaaaaag aactaatcaa gctggcgaac aagggtcaag actatgacca
     1501 cttagcagat gagattgatg agctgagaga caagcgacag atccttttag tagaagatgc
     1561 ctccctcagt ggcgagaacg agcgaatcaa tgagctgatt gaatttatcc gcaagaacaa
     1621 attccgcacc ttagaatatg atgataagct tgtaaggaag ataatccaga gcgttacagt
     1681 ctatgaaggc cacttcgtca tagccttcaa atctggcatc gaaatggaaa tatgaaaacc
     1741 agaagtaaat agcccatgac tctacagtag agttgtgggt tttcttttgc ttgctgatta
     1801 taataatatt ttaataacta ttgtgtttat caaccaaatg gtttataata ttcttagcgt
     1861 aaacttggag gtgctgtatg actacggcag aaatgattaa agaactgtgt gagcaaatga
     1921 atataagtgt ttccgaactt gctagacgta ttggccagac tccacagaat ttcaataaaa
     1981 aattacaacg agaaacagta accttggatg agttgaaggc cattgctgat gtgctaggtg
     2041 tcaagtttgt gcaggcattt attttaccag atggagaaga aataaaaata tctaacgaat
     2101 aaaggaggat gtttatatgg taggtaatgt tattcaaata gtaacagaga aattatcatc
     2161 tttgcctttt atagaaggca tcgtattagg gggctcacgt gcaagaggca cccatacaga
     2221 aaattctgat atagatatcg gaatctatta caattcagac tcatttgacc tgacagcgat
     2281 taatcaaatt gctacagagt tggatgatga gaatagaaac aaccttgttg tacctcccgg
     2341 agcgtggggt gattgggtta atggcggtgg atggttagtt ataaacgggt gtcatgttga
     2401 cttgatatta cgtgatataa aacgggtgga acaaataatc aaagatacgg agcaaggaat
     2461 tgttactgcc aattatcaga ccgggcatcc ccatggttat ataagtgcta tgtatcgtgg
     2521 agaattagcg attagtaaaa tactatatgc taagaacgaa agcttatgcg aattaaaaaa
     2581 gcaggcagaa atttacccta ctgctctaaa gaaaagcttg atgaactttt ttatatttga
     2641 agctgaattc tctttaatgt ttgtaaaagc aaatgcgggg gcagaggata aatattatat
     2701 tgcaggccat gtttttcgta ttatttcatg cttaaatcaa gtactatttg catgtaataa
     2761 tgcttattgc attaacgaaa agaaagctat aaaactgctt gaaacttttg aatataaacc
     2821 tgaaaaatat gccgaaagag ttaatcatat ttttgaagta ctcggtcttt ctctttttga
     2881 atgctacgac atgaccgaga aactttataa agaagtgaat gaaattgtat cggagataaa
     2941 taacttttta aacgaggaga gttcagatga aagaaaacaa atatgatgat aatatatttt
     3001 ttcaaaaata cagtcaaatg agtcgctcgc agaaaggact ggctggtgcg ggagaatggg
     3061 agactttgaa aaagatgcta cctgatttta agggtaagcg tgtgcttgat ttaggatgcg
     3121 gctatggatg gcactgtata tatgcgatgg aaaacggtgc ttcctctgta gtaggtgttg
     3181 atatttctca taaaatgctc gaagtagcaa aaggaaaaac ccattttcca cagattgaat
     3241 atgaatgctg tgccatagaa gatgtggatt tcccagagga gagctttgat gtaatactaa
     3301 gttcgcttgc gtttcattat gtagcagact atgagaattt aataaaaaag atatatagga
     3361 tgctgaaggc tggtggcaat ttagttttta cagttgaaca tcctgttttt actgctcatg
     3421 gaacacaaga ctggtattat aacgaaaaag gagaaatact gcatttcccg gtggacaatt
     3481 attattatga gggcaaacgg acagctatgt ttttggaaga aaaggttaca aaatatcata
     3541 gaacactgac cacatatcta aatacactgc tttcaaatag ttttataata aatcagattg
     3601 tggagccaca gccgccagag aacatgatgg atattccggg gatggcggat gaaatgcgac
     3661 gcccaatgat gctgattgta tcggcaaaaa agaagatgta ataatataga aaaaataaac
     3721 gaggagtatg taaatgagat cagaaaaaga aatgatggat ttagtacttt ctttagcaga
     3781 acaggatgaa cgtattcgaa ttgtgaccct tgaggggtca cgcgcaaata ttaatatacc
     3841 taaagatgaa tttcaggatt atgatattac atattttgta agtgatatag aaccgtttat
     3901 atctaatgat gactggctta atcaatttgg gaatataata atgatgcaaa agccggagga
     3961 tatggaatta ttcccacctg aagaaaaggg attttcctat cttatgctat ttgatgatta
     4021 caataaaatt gatcttacct tattgccctt ggaagagtta gataattacc taaagggcga
     4081 taaattaata aaggttctaa ttgataaaga ttgtagaatt aaaagggaca tagttccgac
     4141 tgatatagat tatcatgtaa gaaagccaag cgcaagggag tatgatgatt gctgcaatga
     4201 attttggaat gtaacacctt atgttattaa aggattgtgc cgtaaggaaa ttttatttgc
     4261 tattgatcat tttaatcaga ttgttcgcca tgagctgctg agaatgatat catggaaggt
     4321 cggcatcgaa acaggcttta aattaagtgt aggcaagaac tataagttta ttgaaaggta
     4381 tatatccgag gatttgtggg agaaactttt gtccacctac cggatggatt cctatgaaaa
     4441 catatgggaa gcattatttc tatgccatca attgttcagg gcggtatccg gtgaggtggc
     4501 ggaaaggctt cattatgcct atccggagta tgataggaat ataacaaaat ataccaggga
     4561 catgtataaa aaatacactg gtaaaaccgg ctgcctggat agcacatatg ccgctgatat
     4621 agaagagagg cgggaacagt gattacagaa atgaaagcag ggcacctgaa agatatcgat
     4681 aaacccagcg aaccatttga ggtgataggt aagattatac cgaggtatga aaacgagaat
     4741 tggaccttta cagaattact ctatgaagcg ccatatttaa aaagctacca agacgaagag
     4801 gatgaagagg atgaggaggc agattgcctt gaatatattg acaatactga taagataata
     4861 tatctttact accaagacga taaatgcgtc ggaaaagtta aactgcgaaa aaattggaac
     4921 cggtacgctt atatagaaga tatcgccgta tgtaaggatt tcagggggca aggcataggc
     4981 agcgcgctta tcaatatatc tatagaatgg gcaaagcata aaaacttgca tggactaatg
     5041 cttgaaaccc aggacaataa ccttatagct tgtaaattct atcataattg tggtttcaaa
     5101 atcggctccg tcgatactat gttatacgcc aactttgaaa acaactttga aaaagctgtt
     5161 ttctggtatt taaggtttta gaatgcaagg aacagtgaat tggagttcgt cttgttataa
     5221 ttagcttctt ggggtatctt taaatactgt agaaaagagg aaggaaataa taaatggcta
     5281 aaatgagaat atcaccggaa ttgaaaaaac tgatcgaaaa ataccgctgc gtaaaagata
     5341 cggaaggaat gtctcctgct aaggtatata agctggtggg agaaaatgaa aacctatatt
     5401 taaaaatgac ggacagccgg tataaaggga ccacctatga tgtggaacgg gaaaaggaca
     5461 tgatgctatg gctggaagga aagctgcctg ttccaaaggt cctgcacttt gaacggcatg
     5521 atggctggag caatctgctc atgagtgagg ccgatggcgt cctttgctcg gaagagtatg
     5581 aagatgaaca aagccctgaa aagattatcg agctgtatgc ggagtgcatc aggctctttc
     5641 actccatcga catatcggat tgtccctata cgaatagctt agacagccgc ttagccgaat
     5701 tggattactt actgaataac gatctggccg atgtggattg cgaaaactgg gaagaagaca
     5761 ctccatttaa agatccgcgc gagctgtatg attttttaaa gacggaaaag cccgaagagg
     5821 aacttgtctt ttcccacggc gacctgggag acagcaacat ctttgtgaaa gatggcaaag
     5881 taagtggctt tattgatctt gggagaagcg gcagggcgga caagtggtat gacattgcct
     5941 tctgcgtccg gtcgatcagg gaggatatcg gggaagaaca gtatgtcgag ctattttttg
     6001 acttactggg gatcaagcct gattgggaga aaataaaata ttatatttta ctggatgaat
     6061 tgttttagta cctagattta gatgtctaaa aagctttaac tacaagcttt ttagacatct
     6121 aatcttttct gaagtacatc cgcaactgtc catactctga tgttttatat cttttctaaa
     6181 agttcgctag atagagttct atattagaga tgtaaagagt tttggtgaag aggtttgtga
     6241 gtatggcttt tataaccagg gtgcaatgag aagcactaac agcagctagc ttaagaacgc
     6301 ataggatata ctttttatgg aagtcacaga ggaggaataa aatttgaaca ggattaacag
     6361 agtaacctct attcttattc agctgcaatc aaaaaaaata attcctgcca aagaaattgc
     6421 acagcgattt aatataagct taaggacagt ttacagagat atccggacac ttgaagaagc
     6481 cggaatacca attggatctg aggccggaaa aggatatttt cttgtagagg gcttcctact
     6541 tccgccggta atgtttacag cggcggaagt gggtgcattg attacagcag ggaaattttt
     6601 aaattgccat ggagatgaat catttataaa ggattttgat tcagctatgt ataaaatcaa
     6661 atctattttg aagcatggtg aaaaaaacta tgcacaggag ttggagaaca gtattaacgt
     6721 gtacagcaca tctggacaga aaaatacatt ggcggataac gttattgcag caattcagac
     6781 tgcaatctgc aataaa
//
LOCUS       DBBGSP010000215         4223 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.guided.133, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000215 DBBGSP010000000
VERSION     DBBGSP010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4223
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.guided.133"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..808
                     /locus_tag="ACIZE9_003241"
     CDS             <1..808
                     /locus_tag="ACIZE9_003241"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGC6095006.1"
                     /translation="TIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQS
                     LGASLEGYTEGNPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQK
                     GGIDTTLAFLDKQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDL
                     VSQITGLEKKIEQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQE
                     LEGLSDFLPIVLSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            1066..2568
                     /gene="eat(A)"
                     /locus_tag="ACIZE9_003242"
     CDS             1066..2568
                     /gene="eat(A)"
                     /locus_tag="ACIZE9_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HGC6095007.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            2635..3162
                     /locus_tag="ACIZE9_003243"
     CDS             2635..3162
                     /locus_tag="ACIZE9_003243"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGC6095008.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            3373..>4223
                     /locus_tag="ACIZE9_003244"
     CDS             3373..>4223
                     /locus_tag="ACIZE9_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HGC6095009.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPA"
BASE COUNT         1434 a          730 c          930 g         1129 t
ORIGIN      
        1 aactatccga cttgcttcca gttatgcctt aggagaactt attaaagatg cactgcttca
       61 agaagtagaa caaattattg tcactttagg aggaagcggg tgtagcgatg gtggtctagg
      121 attactccaa tccttgggtg cttctttaga agggtacaca gaaggaaatc ctttattatc
      181 tactaaaaaa cttcattttg atcgaagaaa cgttcttgtt tctaaagtaa aattgattat
      241 cgctgcagat gttaccaatc catatacagg tcaacaagga gctgcttggc aatttggaag
      301 acaaaaagga ggaatagata cgacgctagc tttcttagat aaacaagcag gaaagattgc
      361 tcagcaaata aaagatttct gggaggtgga tttagatgat attccaggaa gtggagcagc
      421 aggcggtatt ggtggagccc tttttttgtt gggagcgaag atggtttctg gtttcgattt
      481 agtcagccaa atcactggat tggaaaaaaa gatcgaacaa gcagatgtca tcattacagg
      541 agaagggcgg atcgatcagc aaacgatcca cggaaaagtt ccatacggtg tagcagtgct
      601 tgcaaaaaaa tatcgaaaac caataatcgc tatttgcgga agtagagacc aagagctaga
      661 aggactttct gattttctcc caattgtctt aagtattcat ttgggtccaa taggtttaga
      721 agaagcaatg gaacacaggc aaacattaga aaaaacaaaa atcttaggac agacacttag
      781 cagatttttc accatcctcc cgaagtagtt gacaaaatca ttttctttat gctatcgtaa
      841 tttcaaatat aggacaaagt gagggatccg tgcattgaaa aattaagtcg attgatgaaa
      901 gctgcattca gactgtacct tgtggagaca aggaagcagt gtgcagattt tcgggattgg
      961 cttggttttt tcgatgtatg ggtctttttg tgtgtatcca acccttgcat cctctttagc
     1021 cagttctgaa aataggactg gtcttttttt acgaggtgat ggaaaatgtc taaaatcgaa
     1081 ataaaaaatc tgacattcgg ctacgacagc caaggcacat tattatttga acaagcaaat
     1141 ctaaattttg acacacaatg gaaactagga cttatcggac gaaacggtcg aggaaagaca
     1201 actttactga atattctaca aaacaaacta ccttatcaag ggcaagtaat ccatcagcaa
     1261 gaatttgcct atttcccgca acagacaaaa gataaagaac gtttaaccta ttacgtgtta
     1321 aatgatatta cggattttga gatatgggaa atcgaaagag agctccaatt gatgcaaaca
     1381 gatcctgaaa tcttatggag agaattcagc acactatcgg ggggagagaa gacaaaagtc
     1441 ctactggcac ttttatttgt ggatgacact catttcccgt taatcgatga accaacgaat
     1501 catttggata tctctggtag aaaacaagta gcggcttatt tgaaaaagaa aaaacaaggc
     1561 ttcatcgtgg tcagccatga ccggggattt atcgatgaag tagtggacca tgttttagca
     1621 atcgaaaaaa gtcaactgga actttatcaa gggaatttct ctatctatga agaacagaaa
     1681 aaacttcgtg atgaatttga aatggctcaa aatgaaaaat tgaaaaaaga agtcagtagg
     1741 ctaaagaaaa cagcagctga aaaagccgaa tggtctcgtt cccgagaagg agataaaaca
     1801 aagaaacaag tcggattcat cgatactgaa tctagacgag tgaataaagg agcagtgggt
     1861 gctgatgctg cacggacgat gaaacgatcc aaagcaatcg tgaatcggat ggagacccag
     1921 atcagcgaga aagaaaaact attaaaagat atcgaatata tcgattcttt gacgatgaat
     1981 agccaagcgt ctcaccataa gcgactttta agcgtagaag atcttcaatt agggtatgaa
     2041 aatctgttat tcgagccaat tcattttaca atcgagcctc atcagcgggt ggcgatttca
     2101 ggtcctaacg gtgcaggaaa gtcatccatt atccattatc ttctgggggc attcaacggc
     2161 aaggttatag gagaaaaata ccagccaaaa catctgagca ttagttatgc aagccaaaat
     2221 tatgaagaca atcgaggaac gttggcggaa tttgcagaga aaaaccaagt agactaccaa
     2281 gcatttttga acaacctccg aaagcttggg atggaaagag atgtttttca taacaagatc
     2341 gagcagatga gtatgggcca acggaaaaaa gtggaattgg ctaaatcttt atcacagcca
     2401 gctgaactat atacatggga tgaaccattg aattatttgg atgtcttcaa tcaagaacaa
     2461 ttagaacaac tgatcttgaa cgtgaaacct gccatgttac tagtggaaca tgatcaaacc
     2521 ttcctggata aagtatctac tgagattatt tctcttgaga gaatctaacc cttgtaatct
     2581 caagaacaac aaggtatggt taaggggaac tttgccaacg aaggagagaa tcacatgctt
     2641 tatgtaacga gacacggaga aacaacttgg aacgcacaag gattagtttg cggacgggca
     2701 gatgtgccgc tgactgaaaa aggacagatg caggcacaga aactagcaga aaaggtagta
     2761 gatttgcctg ttccaatcac gaaaatcatc cattcccctc ttcaacgagc aagagataca
     2821 gcacaagcag ttgctgatcg tctcagcttg ccgctgaccg ttgatgaacg attggtagaa
     2881 atggattttg gggattatga tggactgcca agcaaagatg agaactttca aaaagcacgt
     2941 ttagcgttcg ctgtacgatt cccaaatggg gagtcagtct tagatgtgta tgcacggatc
     3001 gttcctttat tgaaagaatg catcgaagac gaagaaaatg tctatctgtt agtttgccat
     3061 aatgccttga taagagtgat caatgcttat tttcatccga tgcctaatga ggggttcttt
     3121 acattcatgg tagataatac agaattggtt tcttatgagt aattatgttt ttgtgttatt
     3181 taaataaaat atttcaaggc actgcttttg cttagcagtg ccttttttag gttatgacaa
     3241 ttcttttgat aatataaact caacctttag aaatgaaatt taattatttt aataaaagta
     3301 ttgaaatttt gtttctttag atatatactc tagtcataga aatgaagacg gatacagaaa
     3361 aagagggata atatgtttgg cttttcaata tttatgaacg attctttgtc agaagagaag
     3421 aaacagtata tccgccaaat ggcatccaat ggctttgtcg gtattttcac ttccatgcat
     3481 ataccagaag atgatgtttc ggcatatcaa aagcgattga tcgaactagg aagcgaagcg
     3541 aaaaagaata aactagaatt gatggtcgat atttcaggag aggcattgga acgagcgggt
     3601 ttttcattag aagatctaac gcctttgaaa gcaattggtg taacaggttt aagaatggat
     3661 tatcatattt ccaatcagca gattgccgac tggtcacatc aattgaaaat cagtttgaat
     3721 gctagcacga tcacgcctaa agatatcgat gaattgaaag aagcagaagc tgatttctca
     3781 cagattgaag cttggcataa ttattatcca cgtcccgaaa cagggctgga caaagaatgg
     3841 tatcagaaaa aaaatcaatg gctcaaaatt caaggtctcc ttgtccaagg ttttgtacca
     3901 ggagatacag agttgagagg cccactatat caaggattgc caactttgga agaacatcga
     3961 gggatccatc ctcttgcagg cgctctagat ctattagcaa gtaacacgga tattgtttac
     4021 atcggagatg caggtctgtc agaaaacgtt caggagcaat ttgcttcttt ccaaaaagaa
     4081 cagacagtct tgctccatac ggaacctgta gatgaagaat tttacgaata tatattaggg
     4141 aagcatacga atcggcaaga cgatgcaaga gatgtcatac gaagcgtaga tgcacgtttt
     4201 cgagagattc cgcctatccc agc
//
LOCUS       DBBGSP010000216         3491 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.guided.139, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000216 DBBGSP010000000
VERSION     DBBGSP010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.guided.139"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            205..1683
                     /gene="msr(C)"
                     /locus_tag="ACIZE9_003245"
     CDS             205..1683
                     /gene="msr(C)"
                     /locus_tag="ACIZE9_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HGC6095010.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            1730..2176
                     /locus_tag="ACIZE9_003246"
     CDS             1730..2176
                     /locus_tag="ACIZE9_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HGC6095011.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(2375..2890)
                     /locus_tag="ACIZE9_003247"
     CDS             complement(2375..2890)
                     /locus_tag="ACIZE9_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC6095012.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            3007..>3491
                     /locus_tag="ACIZE9_003248"
     CDS             3007..>3491
                     /locus_tag="ACIZE9_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC6095013.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GP"
BASE COUNT         1088 a          591 c          748 g         1064 t
ORIGIN      
        1 aaacaacaat ttcatggatg gagtatgtcc attttttcga acgacagtag aataggtgaa
       61 agctatgaca gatttggtga tttagtcata gttatttcgt tcagagtagg aaaagatgtg
      121 atgcagtttt tttgcaaaca gatttttctg ctctttttta gtatcgataa ttgttgtttt
      181 acatgaaata ggagtgtaaa acatatggaa aatttagcag taaatataac aaatctacaa
      241 gtcagctttg gcaaccagct agaactatct attgattctc ttcgtgtcta tcagcaagat
      301 cgtataggga tcataggaga aaatggtgtc ggtaaatcga ctttgctcaa actaatagcc
      361 ggtgaacttt ttcccgatca tgggaaaatc caaacagaga tcaccttcaa ctacctgcct
      421 caattaacct atctcgctga agcaaaggac ctaaatttgg aattagccag tcatttccag
      481 ttaagactgg aagaaacttc agagcggaaa tggagcggag gggaagaacg aaagatcgag
      541 ttgatacgtc ttctttcttc ttatgaacaa gggatgcttc tagacgagcc aacaacccat
      601 ctagatagaa aaagtattga tcgactgatt gaagagcttc gttattatta tggtacgctg
      661 gtttttgtta gtcatgatcg ctattttcta gatgagctag catcgaaaat ctgggaagta
      721 aaagacggag aaatccgaga gttttcgggg aattatagtg cctatctcac tcaaaaggaa
      781 ttggagaaaa agactcagct acgagaagca gagtcgatca tgaaagagaa aaaacgattg
      841 gaaaaatcga tccaagaaaa gaaaaaacaa gcggaaaagt tggaaaaagt gtccagtaaa
      901 aagaaaaagc aacaaatcag actggatcgg ttgtcttcct ctaaacaaaa agacagtgta
      961 caaaaagcca tccaaaagaa tgcgaaaaca ttagagagaa gactccaaaa aataggagaa
     1021 acaaccaagc cgcagcagat gaaacaaatc cgttttccag taccaaaatc tcttgaactc
     1081 cacagccgct atcccatcat gggacaaaat gtccaattgg aaagaagtgg gagaacatta
     1141 ctggtaaatg gtgattttca gttttcttta ggtaaaaaaa tcgcgattgt cggtgaaaat
     1201 ggttcaggta agacaacctt attagaacat atccgcaaac aaggagaagg aatccttctc
     1261 tctccgaaag taagctttca agtatatcag caaaagggtt atcaaatgac atctgaagaa
     1321 tccatcattc gttttgtcat gagacaaaca gagttttcag aatcgcttgt ccgtagtttg
     1381 ctgaatcact tagggtttgc tcaggaaact ttgacgaaac cgttatgtac attaagtggg
     1441 ggagaagcga cccgtctgac gattgctttg ctttttacta agccaagtaa tgtgttgctg
     1501 ttagatgaac cgactaattt tattgatatg gcaacgatcg aagctttaga gaagctaatg
     1561 caaatatatc cgggaacgat tttgtttact tctcatgatt cttactttgt cgagcgtacg
     1621 gctgatgaag tttatgaaat aaaagggcag aaaataaaaa aagtacttac gagaaatttt
     1681 taaatgtgct acgatgattt tcgtgacaaa tttaaaggag tggtacagat tgcctacaaa
     1741 taaaaaagaa ggaataattt ttacaacaat gatgtgtttt ttgatggtct tggggatgag
     1801 cgcgtataat ttatggctgc atcaagatct tcatttatca agtttgttga ttggtctagt
     1861 gcctggattc gtggtggctt tcattttgga tgtcttcatc atcggtgtgc tggcgaaaaa
     1921 aattgccttt aaactaccag taaatccaga aagcaaggtc caaatgatct taactatttc
     1981 atgcttgatg gttttaggaa tggtgacatg tatgtcttta ttcggtgtga tcatggaaca
     2041 aggaatacct gatcaattat tctctgctta tatgaatgct tggaaaatga atgtgattgc
     2101 cgctttaccg ttgcagttga tcatcgttgg cccgctttca agaagtgtgc taaaagcaat
     2161 tcaaagtaat gaatgatgga acactgttat ttgaaaaaag gccttggcat gctttttgtc
     2221 atagtctctt gaatgcagtt ctagaaaaat agtgatccga acgataggtt ttggcctgtc
     2281 gttcggatcg ctttttcttt tccaactgta ttgctctttt attgaagata atttgctctt
     2341 caatagatat ttctagaaag gttctgttta tcccttactc aaaaaactgc tgcatttgtt
     2401 ctcttacttg ctgacaccat tggagttcct gctgacaaag cataattctg cgctggatca
     2461 caacataacg tccaaattct tgtttcttgt ctagcgagag gtcattcaat tttttttgat
     2521 ttttttgcat gattttgttc agctgttgtt ctctagtgaa tagcagtcca gtagctgttg
     2581 ttttatcgag cgtcgaaaaa gcatagattt ttgctagaaa ttcatctttt tgcgtaggag
     2641 cgggagtttc ctctttgatc cattcctcta caagagcacg tccttcatca gtcaagtggt
     2701 agatcttttt ttgagagtgc tcgtctttgt ccaaaacggt cacataaccc tgctggtcta
     2761 acttggcaag cgttgtatag atctgactgt gatgggcttc ccaaaaaatt gtgatcagct
     2821 gcttcaattc atacccagaa cgtggtttgg ataaaagcac gcataataat atataggcta
     2881 aagtattcat aaaaatccta cctctcgtct tattttcttt attatatcac agtaaagttt
     2941 ccacgtttta catgtgcata ttgacatgta aaataaatca tgtatgatgc taatagagag
     3001 aaagggatgg aaatattgga gaatcaaata gatatacaag aacaaacaaa tgaagaaaca
     3061 aaggggaaaa gttcagcgct agttgtagca gctacctgta tgatcgcttt tatgggagtg
     3121 ggtctagtag acccaatctt aaaaacgatt gctgcacagt taaacgctac gccagctgaa
     3181 acgaccctgt tatttactag ttacatgtta gtcactggtg tggtgatgct atttacaggt
     3241 ttcttatcta gtcggatcgg tttgaaaaaa acattgatga caggattgtt tatcatcgtt
     3301 gtattcgctg gtcttggcgg attatctggg aatatcggaa tgctgattgg gttacgtgcc
     3361 ggctggggtg tcgggaatgc tttatttgtc tctactgctt tagcaacgat cgtcagtatt
     3421 ttagttggta acacagaaaa agcaatcatg atgtatgaag cagcacttgg ctgcggaatg
     3481 gctgttggcc c
//
LOCUS       DBBGSP010000217         3188 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.guided.140, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000217 DBBGSP010000000
VERSION     DBBGSP010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.guided.140"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            275..772
                     /gene="dfrG"
                     /locus_tag="ACIZE9_003249"
     CDS             275..772
                     /gene="dfrG"
                     /locus_tag="ACIZE9_003249"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HGC6095014.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(844..2796)
                     /locus_tag="ACIZE9_003250"
     CDS             complement(844..2796)
                     /locus_tag="ACIZE9_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HGC6095015.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2803..3039)
                     /locus_tag="ACIZE9_003251"
     CDS             complement(2803..3039)
                     /locus_tag="ACIZE9_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6095016.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT          984 a          551 c          529 g         1124 t
ORIGIN      
        1 taagtagttc agttttggag tacaaaatga caaaatgtac ttcaaaatgg actacttttt
       61 tcattttaac ttacatacca aattacatac aaaatgattt ataaaatgca attgaaaatg
      121 ataattgaat gaaaatttgt gattttgtgg tattatgata atataactta tagaaaaaat
      181 tgcttattca actaacgggc aggataatga gaaaaggttt tttgatagaa ataagaaatt
      241 agatggtaaa ttagttaaaa aggctgtgtt ataaatgaaa gtttctttga ttgctgcgat
      301 ggataagaat agagtgattg gcaaagagaa tgacattcct tggaggattc ccaaggactg
      361 ggaatatgtt aaaaatacta caaagggaca tccgataata ttaggtagga agaaccttga
      421 atcaatcgga agagccttac ctgacagaag aaatattatt ctgacgagag ataaggggtt
      481 tacctttaat ggttgtgaaa ttgttcattc aatagaagat gtttttgagt tatgtaaaaa
      541 cgaagaagaa atttttattt tcggaggaga acagatttat aatttgtttt tcccttatgt
      601 tgagaaaatg tacatcacaa aaatacatca tgaattcgaa ggagatactt tttttccaga
      661 agtgaattat gaggaatgga atgaggtatt tgcccaaaaa gggataaaga atgataaaaa
      721 tccgtataac tactattttc atgtatatga aagaaaaaac ttattgagtt aacgggtgcg
      781 ttaattgaag aagaacagta aagataaagc acaagagctt gggattactc caagctcttt
      841 ttgtcatttg aaataaatta tatctttcca atcaaattgt ttatctgtaa tccctaatct
      901 ttgagcaggt gtcaaaacct ttttatccgc tgatttaaaa gggcgacaaa agttgtagta
      961 agttcttaga attgtaatcg caaattgagc atacttcgga ttgaagttag cgtaaatata
     1021 gctcttctta tcaccacgag ctgttgttaa tggtctttca agagatgata tataacgtct
     1081 tatctgttga ataaagctat tggtcgaatg gtcattaaca tttaatagca tctttgcgat
     1141 ttcgtttggt tccagagcag ataaatccgt tctacaatca actgaataaa atcctttatc
     1201 cttagtggct aatggatgtt tgatagggtt atcggcatat ttgcgatatc tttctccatc
     1261 tttactaata gcctcttcgt ggaattgatg acttgttagt aattcagtta gataatgaga
     1321 tgccaaagtc cgtagaaact ttgttttgaa tcctctgata tctccccaat cgagcagttc
     1381 tgcttttgct tgtccgaatt cttttaagca ttgttttctg cttttcgtct tgttaacttg
     1441 gcaaataaaa tgatgtgcat cgctcaacct taattctttc gtgaatactc tataaaaggc
     1501 gtttctaata gagaagtcat catcactaat cattcgccat tcgtcggcat taaccatttg
     1561 tttaattaac caatagtgag cagttgtagt ataaggagca tcaacattta aaccatcgac
     1621 aaatctactc ctattagtaa ttttccctaa ttcgtgaaga taagcattcc tattttcgct
     1681 atcgttagcg gatggttctt gtggataata agaccaatct aacctatcat ttttacgact
     1741 aaaagtattg agatggtctt ctttgaattt tcttgtatct tcatttaatt catccattga
     1801 aatattccaa tcataggcaa catcagaacg gaacacatat cttgataaga cctcagcaga
     1861 tacaactata tacgtttgca tattaaggtc ttcaaacccc gtatatttct ttgaaccttg
     1921 tcctttctta cggacgttat ttaggtagta gtgcatcttg tccgtattaa gccacatctc
     1981 gttaaatttc tttgtttgaa ggggttgtgt ctcatatcgt tctaaaaact ccaaacaacg
     2041 cctatacagc cactccagct tatgatagta ggttccaact ccaattccta aaatatcaca
     2101 agtacgactg actgaaaccc ttccaacaac catcttagcg aacattggaa gaatggtgtt
     2161 cttttgttgg tgataagtag tggtttcttc tctttttggt agaacattag tgaacttctt
     2221 acacgcctta cattgatagc gttgagattt gcccctactt ttcccccttt tgtaaaattg
     2281 cttcggctca ttgaatgggg ttgattcttc ttccgagcag ccttctttat gaaattgata
     2341 atctggctca acatcttgga tgctattgat ttctataagg cgtttaattt cttcaacaac
     2401 agaccaatta gataaagggg ttactgtaca gttttgcgat acacctctgc caataggatt
     2461 gtcattgcag tacatacctt tatgaccttt atctttggaa ctaccagtca ttttatatcg
     2521 acttggtttc ccttttacat ctttgaattt gtgctgttct ttcccaaaat tacaacaaaa
     2581 cggattgatg cagtaattat attgaatggg atattcagaa ccgttccatt taaaagacgt
     2641 tggcaagaac aacattttgt tataccttgt tgcaaatcgt tttggagtta ataaatcata
     2701 ttgtttagcc ctatctttta attcttcgtt tgaaatcgga attttaacat ctacaatttc
     2761 atcttccttc gtggctaatc ttttaagctt ggtcattgtc tatcaaccca ctctatcttt
     2821 gatacccatt ttttcaacaa tccgcttatt acttcgcttg ttggcaatcc attcaataaa
     2881 cttcttatcg tctaaaatgt tcaataagaa ttcatccact gcttcgcttt cagtacgctc
     2941 tgcatattca gcgtattgct taactatcac ccttacttgc tctgatattt cccaatccac
     3001 agacttagcg ttcttatttt ttggctcaag aaattgcata ggaaaatgca cccctttttg
     3061 cttagtaaat tgtaaccatt ttaacacacc aatttgcatt cctacaataa ttatttcacg
     3121 ttcgcatttt tatatacatt ttaacttaca ttttgtggtg taaattaaca acaaacgttg
     3181 atttaaca
//
LOCUS       DBBGSP010000218         2915 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.guided.141, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000218 DBBGSP010000000
VERSION     DBBGSP010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.guided.141"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..906
                     /locus_tag="ACIZE9_003252"
     CDS             <1..906
                     /locus_tag="ACIZE9_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HGC6095017.1"
                     /translation="LSPDFHIIPTLISDAISADNAKLAAGNQCVSVSHKSEVSEATIL
                     ALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVAYSPDSVADYALMLMLMAIRGAK
                     PTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQAVVKRLRGFGCHVLAYDNSRKM
                     DADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQIGEMKQGAFLINTGRGALVDTGA
                     LVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDHPFLSQLLRMPNVIITPHTAYYT
                     ERVLQDTTEKTIRNCLNFERSLQHE"
     gene            899..1927
                     /gene="vanB"
                     /locus_tag="ACIZE9_003253"
     CDS             899..1927
                     /gene="vanB"
                     /locus_tag="ACIZE9_003253"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HGC6095018.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            1933..2541
                     /locus_tag="ACIZE9_003254"
     CDS             1933..2541
                     /locus_tag="ACIZE9_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HGC6095019.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(2607..2780)
                     /locus_tag="ACIZE9_003255"
     CDS             complement(2607..2780)
                     /locus_tag="ACIZE9_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6095020.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT          775 a          621 c          800 g          719 t
ORIGIN      
        1 ttatcgccgg attttcatat tatccctacg ctgattagcg atgcgatatc ggcagacaac
       61 gcaaaattgg ccgctggcaa tcaatgcgtt agcgtaagcc ataagtccga ggtttccgag
      121 gcgacaattc ttgcgctgag aaaggtcggg gtaaaataca tttctacccg cagcatcggc
      181 tgcgatcaca ttgatacgac tgccgccgag agaatgggaa tctcggttgg cacggttgcg
      241 tattcgccgg acagcgttgc ggattatgct ttgatgctga tgctgatggc catacggggt
      301 gcaaaaccca ccatgcacgc cgtggcgcaa caagatttca gattggatcg tatccggggg
      361 aaagaactgg gggatatgac tgtgggagtt attggaaccg gccatatcgg gcaagcggtc
      421 gtcaaaaggc tgcggggatt tggatgccat gtgctggcct atgataacag ccgaaaaatg
      481 gatgcagatt atgtccagct tgatgagctt ctaaaaaaca gcgatattgt tacgctccat
      541 gtgccgcttt gtgcggatac ccgccatctg atcggtcaga agcaaattgg agagatgaag
      601 caaggcgcat ttttaatcaa caccgggcgc ggagcgcttg tcgataccgg ggcgctggtg
      661 gaggcgttgg aaagcggaaa gctgggtggt gcggcactgg atgtgttgga gggcgaggat
      721 cagtttgttt ataccgattg ctcgcagaaa gtgcttgacc atcccttttt gtcgcagctt
      781 ttaaggatgc cgaatgtgat catcacaccc catacggcgt actacactga gcgtgtgctg
      841 caggatacta cagaaaaaac aatcaggaat tgtctcaatt ttgaaaggag tttacagcat
      901 gaatagaata aaagtcgcaa tcatcttcgg cggttgctcg gaggaacatg atgtgtcggt
      961 aaaagccgca atagaaattg ctgcgaacat tgatacggaa aaattcgatc cgcactacat
     1021 cggaattaca aaaaacggtg tatggaagct atgcaagaag ccatgtacgg aatgggaagc
     1081 cgacagtctc cccgccatac tctccccgga taggaaaacg catgggctgc ttgtcatgaa
     1141 agaaagcgaa tacgaaacac ggcgtattga tgtggctttc ccggttttgc atggcaaatg
     1201 cggggaggat ggtgcgatac aggggctgtt tgtattgtct ggtatcccct atgtgggctg
     1261 tgatattcaa agctccgcag cttgcatgga caaatcactg gcctacattc ttacaaaaaa
     1321 tgcgggcatc gccgttcccg aatttcaaat gattgataaa ggtgacaagc cggaggcggg
     1381 tgcgcttacc taccctgtct ttgtgaagcc ggcacggtca ggttcgtcct ttggcgtaac
     1441 caaagtaaac ggtacggaag aacttaacgc tgcgatagaa gcggcaggac aatatgatgg
     1501 aaaaatctta attgagcaag cgatttcggg ctgtgaggtc gggtgtgcgg tcatggggaa
     1561 cgaggatgat ttgattgtcg gcgaagtgga tcaaatccgg ctgagccacg gtatcttccg
     1621 catccatcag gaaaacgagc cggaaaaagg ctcagaaaat gcgatgatta cagttcccgc
     1681 agacattccg gtcgaggaac gaaatcgggt gcaggaaacg gcaaagaaag tatatcgggt
     1741 gcttggatgc agagggcttg cccgtgttga tctttttttg caggaggatg gcggcatcgt
     1801 tctaaatgag gtcaataccc tgcccggttt tacatcgtac agccgctacc cacgtatgat
     1861 ggccgccgca ggaatcacgc ttcctgcact gattgacagc ctgattacat tggcgttaaa
     1921 gaggtgataa gtatggaaaa tggttttttg tttttagatg aaatgttgca tggcgtccgt
     1981 tgggatgcca agtacgccac atgggataac ttcacaggaa aaccggtgga tgggtatgag
     2041 gtgaatcgca tcatcggcac aaaggccgtg gcgtttgctc tgcgcgaggc acaaatccat
     2101 gcggctgcgc ttggctatgg cttgctttta tgggatggat atcggccaag aactgcggtg
     2161 gactgcttcc tgcgttgggc agcgcaaccg gaggacaatc tcacaaaaga aaaattttac
     2221 cccaatatag agcgagccga gttgattaca aagggttatg tggcctcaca atccagccat
     2281 agccgtggaa gcgcaattga tcttacgctc taccacctgg atacagggga acttgtttca
     2341 atgggaagta acttcgattt tatggacgaa cggtcgcatc atacagcaaa agggataggg
     2401 gatgcagagg cacaaaatcg aagatgcttg cgtaaaatca tggaaagcag cggatttcag
     2461 tcttatcgct ttgaatggtg gcactataag ttgattgatg agccataccc cgatacctat
     2521 tttaattttg ccgtttcata atgaaagtat tggttttgta tcagattttg gatttgataa
     2581 aatctatgct ggtcatggac aatcttttac tggaaagtgg ttaaagcatc ttttgtaata
     2641 cattgcaaat tatagtattc aatctgccca gcggcagaaa agaaaaaaac cgctgttggg
     2701 cagacctttc ccacgcccat tttgtatttt gctggcggcg gttttgagaa atcaaggccg
     2761 ccgttctttt ctggcagcaa aaggtgtggc ggcccatagg aggatgccgc tatgctgttt
     2821 tgctattgcc atgctctaat ccacttccac cactcaaaaa aagccttgcc cctccatgaa
     2881 ctgaacccca aaagttgaac tatttaatgg actgt
//
LOCUS       DBBGSP010000219         2771 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.guided.142, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000219 DBBGSP010000000
VERSION     DBBGSP010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.guided.142"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            110..193
                     /locus_tag="ACIZE9_003256"
     CDS             110..193
                     /locus_tag="ACIZE9_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HGC6095021.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            318..1055
                     /gene="erm(B)"
                     /locus_tag="ACIZE9_003257"
     CDS             318..1055
                     /gene="erm(B)"
                     /locus_tag="ACIZE9_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HGC6095022.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1318..2181)
                     /locus_tag="ACIZE9_003258"
     CDS             complement(1318..2181)
                     /locus_tag="ACIZE9_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HGC6095023.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2183..2455)
                     /locus_tag="ACIZE9_003259"
     CDS             complement(2183..2455)
                     /locus_tag="ACIZE9_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HGC6095024.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2472..2681)
                     /locus_tag="ACIZE9_003260"
     CDS             complement(2472..2681)
                     /locus_tag="ACIZE9_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HGC6095025.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          851 a          487 c          443 g          990 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa attttgtata ataggaattg
       61 aagttaaatt agatgctaaa aatttgtaat taagaaggag ggattcgtca tgttggtatt
      121 ccaaatgcgt aatgtagata aaacatctac cgttttgaaa cagactaaaa acagtgatta
      181 cgcagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
      241 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttat agatgtaatc
      301 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
      361 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      421 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      481 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      541 ctcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      601 ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      661 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      721 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      781 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      841 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      901 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      961 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
     1021 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt ttgtaaattt
     1081 ggaaagttac acgttactaa agggaatgta gataaattat taggtatagg gcacctctaa
     1141 taactaccaa ttaattcacc tcaaaatgaa attagaaaaa aacagcgaaa tttttaaatc
     1201 tatttcttat cgatacaaat tcctcgtagg cgctcgggac cccaacatga ggaaatgttt
     1261 ttataaaaaa agagtagtta ccgttttttg gtaactactc ttttcctttt ttaaggttta
     1321 aatacctgga agtttaggtg ttttgggtat tggtggtgta ggtagctgca agctttccat
     1381 tttttgttga attgctttaa attcaggggt ttcttggtgt tgattttgaa ccattttttg
     1441 ctctattctc tccaaagtcg gttgaatttc tttccctgat actttacgat ttaattctct
     1501 ttctaaggtc tctttcggac taatggaagg cgtttctaag cttgaataga gtttcactcc
     1561 ttctctattg taaagcctta tatcgctaaa taagcccgtt ttatgaaggg tttctaaatt
     1621 ggtcggtaag tttttgacaa caatatcatg cgcttgtttt ggtgttgccc tagctgtcat
     1681 tggatcatct gcatacatgg tttcatatcg ttcaatcgtt cctaagtatg attcaatttt
     1741 cggtactgcc atgacgtata tttttgtttc ataaccttta gattgaagca ttgtggctgt
     1801 ttgaatggga acgtctgttg ttcgtcctgt tccttcaatc actaaattat agccttgatc
     1861 gcttaaacgg ctaataagtg cttctgtcat gcgattcgaa taaggggtaa cgtgttttac
     1921 tacgtctttt tcatagagtt tcactaattc gtcaaaattt gggtgctgtt gtttaaaggt
     1981 atcattatca atgacaataa cattcccttg tgtttcttca aaaattgctg atcgcaaact
     2041 ggttttccct gaccctggtt gcccaccaag taaaaaagcg gttggcgatt caaccgctag
     2101 tctattttta gttagtcgtt caacattctt ttctaaacga tcttcaaatt gcttttcggt
     2161 gaagtcagta atattcgcca tgttaagcca ctttctcttt attcaaaatt tgttttgaat
     2221 attgattcat tgaccgccaa tactcatgaa tagcttgtaa ttcttcaaat ggttgttgaa
     2281 ataaatcaac ttcttgtgcc acttctaatt gatttaaaag attcacttct agtaaacgag
     2341 tatttttagt atctagttca tgattcaaaa cataatttaa tacccgatta taaacacttg
     2401 ccgataactc attaatgatt tcaatttcaa atgttttttc atacgtaact gccatttcat
     2461 tttcactcct tttaaagttt gtcaggtaaa tatttccgta tatattcttc taaggcttga
     2521 tccataactt cttttacgtt tccgccattc tttgctgttt cgatttttat gatatggtgc
     2581 aagtcggcac gaacacgaac cgtcttatcc cccattatat ctttttttgc gctgattggc
     2641 gtatcatttc gttttgcttt ctgtgcgcct aaatttccca cgatcgctca cttctttcta
     2701 tttcttctta ctatttattt tatcatcacc tatcacaaat cacaagtgat ttgtgattaa
     2761 tcacttgtga t
//
LOCUS       DBBGSP010000220         2722 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.guided.144, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000220 DBBGSP010000000
VERSION     DBBGSP010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.guided.144"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(<1..411)
                     /locus_tag="ACIZE9_003261"
     CDS             complement(<1..411)
                     /locus_tag="ACIZE9_003261"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6095026.1"
                     /translation="MDQNILYGYSDPPLARLRRSRFACWGHPKPQQNARPLFCECTLR
                     YGFSHRQGLCVLPPVALAALRAADSVLIPFKTVENQQVYIPHIFIIRVLAVTGNVIIA
                     KCKSQNIFLKKPYLPGIKINHPILKGALDQQLSNV"
     gene            653..1312
                     /gene="vanR-B"
                     /locus_tag="ACIZE9_003262"
     CDS             653..1312
                     /gene="vanR-B"
                     /locus_tag="ACIZE9_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-B"
                     /protein_id="HGC6095027.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALLDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            1315..2658
                     /gene="vanS-B"
                     /locus_tag="ACIZE9_003263"
     CDS             1315..2658
                     /gene="vanS-B"
                     /locus_tag="ACIZE9_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-B"
                     /protein_id="HGC6095028.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
BASE COUNT          794 a          536 c          685 g          707 t
ORIGIN      
        1 gacattggat aactgctggt ctaatgcgcc tttgagtatg gggtgattga ttttaatacc
       61 ggggaggtac ggctttttga ggaaaatatt ctgggattta catttggcga ttattacatt
      121 tcctgtaact gcaaggacac ggatgatgaa gatatgagga atatagactt gctgattttc
      181 tactgtcttg aacggtatta ggactgaatc tgctgcgcgg agtgcggcaa gagcgaccgg
      241 agggagtaca cacaggccct gcctgtgtga aaagccatac cgcaaggtgc attcgcaaaa
      301 aagaggccgc gcattttgct gaggcttggg gtgtccccaa caagcaaaac gagaacgccg
      361 caggcgggca agtggtggat cagaatatcc gtaaaggata ttctgatcca ttgcttgcca
      421 gtattatcgg gatgttttga caaccgctgt aatcgaaaca tcccaaacat taagaaggtg
      481 ttaattatta ttatcttgat ttaattcgtt taaaccaata atatagatac atacaccatg
      541 aaaagaagcg agtatcccaa tgacggatga ttaaaatccg aaaagaaatc gctttgaaac
      601 tacagggaaa ctacagactg ttatgttatc ttcttaaaat ggagggattt ttatgtcgat
      661 acgaattcta cttgtcgagg atgatgatca tatctgtaat acagtaaggg cgtttctggc
      721 tgaggcagga tatcaggtgg atgcctgcac agatggaaat gaggcataca ccaagtttta
      781 cgaaaacact tatcaactgg ttattcttga tattatgctg cccggtatga acgggcatga
      841 acttttgcgt gaatttcgtg cgaaaaatga tactcccatt ctgatgatga cagccctgtt
      901 ggatgacgaa aaccaaatcc gggcgtttga tgcagaggca gacgactatg taacaaagcc
      961 attcaagatg cagattttac taaagcgggt ggaagccctg ctgcggcgca gcggtgcgct
     1021 ggcaaaggaa atccgtgtcg gcaggctgac acttctgccg gaggatttca cggtactttg
     1081 tgacggtaca gagctgcccc tgacacgaaa agaatttgaa atccttttgc tgctggtgca
     1141 gaacaaaggc agaaccttaa cgcatgaaat cattttgtca cgtatatggg gatatgactt
     1201 tgagggtgat ggcagcacag tccacactca tatcaaaaat ttgcgggcca agctgccgga
     1261 aaatatcatc aaaaccattc gcggtgtagg ataccgattg gaggaatcat aataatggaa
     1321 agaaaaggga ttttcattaa ggttttttcc tatacgatca ttgtcctgct actgcttgtc
     1381 ggtgtaacag caacactgtt tgcacagcaa tttgtgtctt atttcagagt gatggaatta
     1441 cagcaaacag taaaatccta tcagccattg gtggaactga ttcagaatag cgataggctt
     1501 gatattcaag aggtggcagg gctgtttcac tacaataacc aatcctttga gttttatatt
     1561 gaagataaag agggaagcgt actctatgcc acaccaaatg ccaatacatc aaatagtttt
     1621 agacccaact ttctttatgt ggtacataga gatgataata tttcgattgt tgctcaaagc
     1681 aaggcaggtg tgggattgct ttatcaaggg ctgacaattc ggggaattgt tatgattgcg
     1741 ataatggttg tattcagcct tttatgcgcg tatatctttg cgcggcaaat gacaacgccg
     1801 atcaaagcct tagcggacag tgcgaataaa atggcaaacc tgaaagatgt accgccgccg
     1861 ctggagcgaa aggatgagct tggcgcactg gctcatgata tgcattccat gtatgtcagg
     1921 ctgaaagaaa ccatcgcaag gctggaggat gaaatcgcaa gggaacatga gttggaggaa
     1981 acacagcgat atttctttgc ggcagcttct catgagctaa aaacgcccat cgcggctaca
     2041 agcgttctgt tggagggaat gcttgaaaat atcggtgact acaaagatca ttctaagtat
     2101 ctgcgcgaat gcatcaaaat gatggatagg cagggcaaaa tcatttccga aatactggag
     2161 cttgtcagcc tgaatgatgg gagaatcgta cccatagctg aaccgttgga catagggcgc
     2221 acggttgccg agttgctgcc cgattttcaa accttggcag aggcaaacaa ccagcggttc
     2281 gtcacagata ttccagccgg gcaaattgtc ctgtccgatc cgaggctgct ccaaaaggca
     2341 ctatccaatg tcatattgaa tgcagttcag aacacgccgc agggaggcga ggtacggata
     2401 tggagtgagc ctggtgctga aaaatgccgc ctttttgttt tgaacatggg cgttcacatt
     2461 gatgatactg cgcttccaag gctgttcacc ccattctatc gcattgatca ggcgcgaagc
     2521 agaaaaagtg ggcgaagcgg tttaggactt gccatcgtac aaaaaacgct ggatgccatg
     2581 agcctccagt atgcgctgga aaacacctcg gatggcgttt tgttctggct ggatttaccg
     2641 ctcacatcaa cattgtaaat atttaaaact taaatgattt tgggctcttt gtcaaatagg
     2701 actgatagag tgagataaga ac
//
LOCUS       DBBGSP010000221         2480 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.guided.146, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000221 DBBGSP010000000
VERSION     DBBGSP010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.guided.146"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..501
                     /locus_tag="ACIZE9_003264"
     CDS             <1..501
                     /locus_tag="ACIZE9_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HGC6095029.1"
                     /translation="QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYR
                     TTEKQQEIMDEKIAEYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHST
                     GNEVYRWLDENSYRFGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEE
                     YLKPEK"
     gene            519..1199
                     /locus_tag="ACIZE9_003265"
     CDS             519..1199
                     /locus_tag="ACIZE9_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HGC6095030.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGETF
                     SFWWLVRHADKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGH
                     EVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVFADKEP
                     QALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPES
                     VDIQEENQ"
     gene            1196..2167
                     /locus_tag="ACIZE9_003266"
     CDS             1196..2167
                     /locus_tag="ACIZE9_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HGC6095031.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2160..>2480
                     /locus_tag="ACIZE9_003267"
     CDS             2160..>2480
                     /locus_tag="ACIZE9_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HGC6095032.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAI"
BASE COUNT          710 a          511 c          682 g          577 t
ORIGIN      
        1 cagtacgatg tggagcttga gcaactatca aatggtgagc ggatagatat tcggatttct
       61 ccctatcttc aagatttgtt tgatgccgca agaactgatg gagtttaccc gattgtcgca
      121 tccggatacc gaacaacaga aaaacagcaa gaaattatgg atgaaaaaat tgccgaatat
      181 aaggcgaaag gctacacctc tgcacaggct aaagcggaag cagaaacttg ggtggccgtg
      241 ccgggaacga gcgagcatca gcttggtctt gctgtggata tcaatgcgga cggaattcat
      301 tcaacaggca acgaggttta tagatggctg gatgaaaaca gctatcgttt tggttttatt
      361 cgtcgctacc caccagacaa gacagagata accggtgtga gcaacgagcc gtggcattac
      421 cgatatgttg gcatcgaagc tgccacagag atgtacaacc aaggggtttg ccttgaggaa
      481 tatttaaaac cagaaaaatg agaaaaggat gttatgttat ggacagaaaa agattgacac
      541 agcgtttccc gttcctgctt ccaatgagac gggcgcagag aaaaatgtgc ttttatgcgg
      601 gaatgagatt tgacggctgt cgctatgcgc agacgatagg ggaaaccttt tctttctggt
      661 ggctggtacg ccatgcggac aaagataccc cctataaaga cggccttacg gtgaccaatg
      721 gtaaactcac caccatgtcg ggcggcggta tgtgccagat gagcaattta ctattttgga
      781 tgttcctgca tacgccattg acaattatcc agcgcagagg tcacgaagta aaggagtttc
      841 cagagccaaa cagtgacgag attaaagggg tggatgcaac catttcagag ggctggattg
      901 atttaaaagt gcgaaacgat accgactgca cctaccaaat atgggtgacc ttagatgatg
      961 agaaaatcat cggtcaggtg ttcgccgaca aagagcccca agcattatac aaaattacaa
     1021 atggcagtat ccagtatgtc cgtgaaagtg gcgggattta tgaatatgcc caggttaaac
     1081 ggatgcaagt tgccttaggt accggggaaa taatagattg caagctgctt tatacaaaca
     1141 aatgcaaaat ctgttatccc ctcccggaaa gtgtggatat tcaggaggag aaccaatgag
     1201 aaaaagtgtg ggcattactg tttttggatg cgaacaggat gaggcaaatg ctttccgcgc
     1261 tttatcgccg gattttcata ttatccctac gctgattagc gatgcgatat cggcagacaa
     1321 cgcaaaattg gccgctggca atcaatgcgt tagcgtaagc cataagtccg aggtttccga
     1381 ggcgacaatt cttgcgctga gaaaggtcgg ggtaaaatac atttctaccc gcagcatcgg
     1441 ctgcgatcac attgatacga ctgccgccga gagaatggga atctcggttg gcacggttgc
     1501 gtattcgccg gacagcgttg cggattatgc tttgatgctg atgctgatgg ccatacgggg
     1561 tgcaaaaccc accatgcacg ccgtggcgca acaagatttc agattggatc gtatccgggg
     1621 gaaagaactg ggggatatga ctgtgggagt tattggaacc ggccatatcg ggcaagcggt
     1681 cgtcaaaagg ctgcggggat ttggatgcca tgtgctggcc tatgataaca gccgaaaaat
     1741 ggatgcagat tatgtccagc ttgatgagct tctaaaaaac agcgatattg ttacgctcca
     1801 tgtgccgctt tgtgcggata cccgccatct gatcggtcag aagcaaattg gagagatgaa
     1861 gcaaggcgca tttttaatca acaccgggcg cggagcgctt gtcgataccg gggcgctggt
     1921 ggaggcgttg gaaagcggaa agctgggtgg tgcggcactg gatgtgttgg agggcgagga
     1981 tcagtttgtt tataccgatt gctcgcagaa agtgcttgac catccctttt tgtcgcagct
     2041 tttaaggatg ccgaatgtga tcatcacacc ccatacggcg tactacactg agcgtgtgct
     2101 gcaggatact acagaaaaaa caatcaggaa ttgtctcaat tttgaaagga gtttacagca
     2161 tgaatagaat aaaagtcgca atcatcttcg gcggttgctc ggaggaacat gatgtgtcgg
     2221 taaaagccgc aatagaaatt gctgcgaaca ttgatacgga aaaattcgat ccgcactaca
     2281 tcggaattac aaaaaacggt gtatggaagc tatgcaagaa gccatgtacg gaatgggaag
     2341 ccgacagtct ccccgccata ctctccccgg ataggaaaac gcatgggctg cttgtcatga
     2401 aagaaagcga atacgaaaca cggcgtattg atgtggcttt cccggttttg catggcaaat
     2461 gcggggagga tggtgcgata
//
LOCUS       DBBGSP010000222         2140 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.guided.152, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000222 DBBGSP010000000
VERSION     DBBGSP010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2140
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.guided.152"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..385
                     /locus_tag="ACIZE9_003268"
     CDS             <1..385
                     /locus_tag="ACIZE9_003268"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6095033.1"
                     /translation="EKLREIFKTAVFNSNQSVLLTVSPQLLNNPRFLAMQIEQMYEIV
                     VPEFVEPVLEQGIKDKSLEIENSHEIAEVIMVLSNVWLNPLVEMTDKEGMEKRCNTFN
                     ALLNGIGIDTLLDEETISAFIQFCK"
     gene            492..1730
                     /gene="mef(H)"
                     /locus_tag="ACIZE9_003269"
                     /gene_synonym="mefH"
     CDS             492..1730
                     /gene="mef(H)"
                     /locus_tag="ACIZE9_003269"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HGC6095034.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            1957..>2140
                     /locus_tag="ACIZE9_003270"
     CDS             1957..>2140
                     /locus_tag="ACIZE9_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016438386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma-70"
                     /protein_id="HGC6095035.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCF"
BASE COUNT          680 a          303 c          382 g          775 t
ORIGIN      
        1 agaaaagtta agagaaatat ttaagacagc ggtattcaat tctaaccaaa gcgttttatt
       61 gacagtttct cctcaactat taaacaatcc tcgttttctt gctatgcaaa tagaacaaat
      121 gtatgaaatt gtagtacctg aatttgttga acccgtttta gaacaaggta tcaaggataa
      181 gtctttggag attgaaaatt cacatgaaat tgcagaagtt atcatggtat taagtaatgt
      241 atggctcaac ccattagttg aaatgacgga taaagagggt atggaaaaac gttgcaatac
      301 attcaatgcc cttttaaatg gaataggcat agacacatta ttagacgaag aaacaatttc
      361 tgcatttata cagttttgta aataactgta tttgttatcc ctatacgata gactgctcta
      421 taaaagagca gtttatttaa accattatat aaaccgacgg tctgtttgat taaataaaaa
      481 ggagagattt tatgcaagca gaaaaaaaac tttttaatcg tgattttata cttgttgtta
      541 taggacagat aatttcttta tttggaaacg ctatcctacg atttgcatta ccgtactatt
      601 tgttaaaaga aactggttca tcagctttgt ttggtattgc tacagcctgc tcttttttac
      661 ctatggttat tttgtcgctg gtaggtggta ttattgctga caggacaaat aaaagaaaca
      721 ttatggtcat actagatttt gtaacagcaa tcataatttt agtattttat ttgtcattgg
      781 gaaaaattcc tatcatacct ttgtttattg ttgctttgat gttactttat ggtatttctg
      841 gtgcatatca accagcggta caagcaagta ttcctctatt ggtatcatca gataaactta
      901 ccgtcggtaa tgctataata aatcaagtaa atactttagc aaactttatc ggaccagcta
      961 taagcggagt agtttttcaa ttttatggta tcaatcccat tttaattgtt agtattatat
     1021 gttttacttt ttcagccatt atggaaattt ttatccatat tccacaccaa aaaagacctc
     1081 gtgaagtagg tgtaattgca gttgctaaaa acgatttaaa agatagttat acctttttga
     1141 aaaaggagaa acccattttt atatccgtaa tctttttggt ttgcattttc aatttggttt
     1201 taagtgctgt tttaattgtt ggtctgccta tcttaatttc tgaagtttta aaaatgccag
     1261 atacactata tggtttttca caatcagcat tatcattagg tggtttatgt ggtggtattt
     1321 taacagctct tgttgcttca aagttaaaac taaaaaacct ttataccttg ttacttattt
     1381 gttctgtttc tgttttactt atgggaattt cgctattttt agaattgcct gcaatagttt
     1441 cctactgggt agttacagtg atgtgctttg tggctatggg tgtatctact atgtttgttg
     1501 ttcaaattta cactcttgtt cagacacaaa caccaccgca attagtagga aagataatgg
     1561 ctacgctggt agcagttgct atgtgcggtc aacctattgg acaaatggtt tacggtattt
     1621 tattcgatgt atttatacaa gaaacatggg ttgttatgtt tgtagcttct attgcttcaa
     1681 tcatgatttc aatatattca aaaagaattt ttcaaaagtt agagatataa tacaaggggt
     1741 taaatagtat gttaggctaa aaacaatata taaaagaaaa tttgaaatct gctaaaagga
     1801 tagtgttata aaagaaagag taatattgca gtatttaagg ctcgcacaaa tatatgtttt
     1861 gtgtgggctt ttttcttacc atttttctgt atttctaaag ggtataaacg gtattccgtt
     1921 tatatatttc agcattagca gaaagggggt gagattatga ggacatcttc tttcgagcat
     1981 atcgtcagat tacagttcaa ttctttaatg ctgattgtca ttaagaacaa agtgaaaagt
     2041 cgaaacagac agcttgcaag acattctaaa cgtgaagtat tgttttgtga aatagccgaa
     2101 acgaaacaag ttgaacgtgg aacgattgat acctgttttt
//
LOCUS       DBBGSP010000223         1772 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.guided.155, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000223 DBBGSP010000000
VERSION     DBBGSP010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.guided.155"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            <1..784
                     /locus_tag="ACIZE9_003271"
     CDS             <1..784
                     /locus_tag="ACIZE9_003271"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGC6095036.1"
                     /translation="DNTNSPCIAPSSPVLHGKCGEDGAIQGLFVLSGIPYVGCDIQSS
                     AACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEAGALTYPVFVKPARSGSSFGVTKVN
                     GTEELNAAIEAAGQYDGKILIEQAISGCEVGCAVMGNEDDLIVGEVDQIRLSHGIFRI
                     HQENEPEKGSENAMITVPADIPVEERNRVQETAKKVYRVLGCRGLARVDLFLQEDGGI
                     VLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDSLITLALKR"
     gene            790..1398
                     /locus_tag="ACIZE9_003272"
     CDS             790..1398
                     /locus_tag="ACIZE9_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HGC6095037.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(1464..1637)
                     /locus_tag="ACIZE9_003273"
     CDS             complement(1464..1637)
                     /locus_tag="ACIZE9_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC6095038.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT          470 a          381 c          469 g          452 t
ORIGIN      
        1 agacaataca aacagcccct gtatcgcacc atcctccccg gttttgcatg gcaaatgcgg
       61 ggaggatggt gcgatacagg ggctgtttgt attgtctggt atcccctatg tgggctgtga
      121 tattcaaagc tccgcagctt gcatggacaa atcactggcc tacattctta caaaaaatgc
      181 gggcatcgcc gttcccgaat ttcaaatgat tgataaaggt gacaagccgg aggcgggtgc
      241 gcttacctac cctgtctttg tgaagccggc acggtcaggt tcgtcctttg gcgtaaccaa
      301 agtaaacggt acggaagaac ttaacgctgc gatagaagcg gcaggacaat atgatggaaa
      361 aatcttaatt gagcaagcga tttcgggctg tgaggtcggg tgtgcggtca tggggaacga
      421 ggatgatttg attgtcggcg aagtggatca aatccggctg agccacggta tcttccgcat
      481 ccatcaggaa aacgagccgg aaaaaggctc agaaaatgcg atgattacag ttcccgcaga
      541 cattccggtc gaggaacgaa atcgggtgca ggaaacggca aagaaagtat atcgggtgct
      601 tggatgcaga gggcttgccc gtgttgatct ttttttgcag gaggatggcg gcatcgttct
      661 aaatgaggtc aataccctgc ccggttttac atcgtacagc cgctacccac gtatgatggc
      721 cgccgcagga atcacgcttc ctgcactgat tgacagcctg attacattgg cgttaaagag
      781 gtgataagta tggaaaatgg ttttttgttt ttagatgaaa tgttgcatgg cgtccgttgg
      841 gatgccaagt acgccacatg ggataacttc acaggaaaac cggtggatgg gtatgaggtg
      901 aatcgcatca tcggcacaaa ggccgtggcg tttgctctgc gcgaggcaca aatccatgcg
      961 gctgcgcttg gctatggctt gcttttatgg gatggatatc ggccaagaac tgcggtggac
     1021 tgcttcctgc gttgggcagc gcaaccggag gacaatctca caaaagaaaa attttacccc
     1081 aatatagagc gagccgagtt gattacaaag ggttatgtgg cctcacaatc cagccatagc
     1141 cgtggaagcg caattgatct tacgctctac cacctggata caggggaact tgtttcaatg
     1201 ggaagtaact tcgattttat ggacgaacgg tcgcatcata cagcaaaagg gataggggat
     1261 gcagaggcac aaaatcgaag atgcttgcgt aaaatcatgg aaagcagcgg atttcagtct
     1321 tatcgctttg aatggtggca ctataagttg attgatgagc cataccccga tacctatttt
     1381 aattttgccg tttcataatg aaagtattgg ttttgtatca gattttggat ttgataaaat
     1441 ctatgctggt catggacaat cttttactgg aaagtggtta aagcatcttt tgtaatacat
     1501 tgcaaattat agtattcaat ctgcccagcg gcagaaaaga aaaaaaccgc tgttgggcag
     1561 acctttccca cgcccatttt gtattttgct ggcggcggtt ttgagaaatc aaggccgccg
     1621 ttcttttctg gcagcaaaag gtgtggcggc ccataggagg atgccgctat gctgttttgc
     1681 tattgccatg ctctaatcca cttccaccac tcaaaaaaag ccttgcccct ccatgaactg
     1741 aaccccaaaa gttgaactat ttaatggact gt
//
LOCUS       DBBGSP010000224         1759 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.guided.156, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000224 DBBGSP010000000
VERSION     DBBGSP010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.guided.156"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            194..1000
                     /locus_tag="ACIZE9_003274"
     CDS             194..1000
                     /locus_tag="ACIZE9_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HGC6095039.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            1018..1698
                     /locus_tag="ACIZE9_003275"
     CDS             1018..1698
                     /locus_tag="ACIZE9_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HGC6095040.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGETF
                     SFWWLVRHADKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGH
                     EVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVFADKEP
                     QALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPES
                     VDIQEENQ"
BASE COUNT          536 a          364 c          447 g          412 t
ORIGIN      
        1 gatagaatga ttttctatca gtcctagaaa ttatagagcc gattttgacc gacaggtata
       61 accctgccgg tctttttttg ctgctacagg aaaactacag actggctaca gggaaagtac
      121 agatgcgctt gccataataa caatcgtacc agccacaaat cgtagtttta ttgcaaagga
      181 ggcattcgat caaatggaaa aaagcaacta tcattccaat gcggatcatc acaaacggca
      241 tatgaaacaa tccgtggaaa agcgggcttt tctatgtgcg ttcattattt cgttcacagt
      301 ctgcacgctg tttttggggt ggagactggc ttccgtattg gaggcaacac agataccgcc
      361 catccctgca actcatacag gcagcagcac tgacgtagtg gagaatttgg aggaaaacgc
      421 tcttgccacc gccaaagaac agggagatga acaggaatgg agcctgattt tagtgaacag
      481 gcagaacccc atccccgcac agtacgatgt ggagcttgag caactatcaa atggtgagcg
      541 gatagatatt cggatttctc cctatcttca agatttgttt gatgccgcaa gaactgatgg
      601 agtttacccg attgtcgcat ccggataccg aacaacagaa aaacagcaag aaattatgga
      661 tgaaaaaatt gccgaatata aggcgaaagg ctacacctct gcacaggcta aagcggaagc
      721 agaaacttgg gtggccgtgc cgggaacgag cgagcatcag cttggtcttg ctgtggatat
      781 caatgcggac ggaattcatt caacaggcaa cgaggtttat agatggctgg atgaaaacag
      841 ctatcgtttt ggttttattc gtcgctaccc accagacaag acagagataa ccggtgtgag
      901 caacgagccg tggcattacc gatatgttgg catcgaagct gccacagaga tgtacaacca
      961 aggggtttgc cttgaggaat atttaaaacc agaaaaatga gaaaaggatg ttatgttatg
     1021 gacagaaaaa gattgacaca gcgtttcccg ttcctgcttc caatgagacg ggcgcagaga
     1081 aaaatgtgct tttatgcggg aatgagattt gacggctgtc gctatgcgca gacgataggg
     1141 gaaacctttt ctttctggtg gctggtacgc catgcggaca aagatacccc ctataaagac
     1201 ggccttacgg tgaccaatgg taaactcacc accatgtcgg gcggcggtat gtgccagatg
     1261 agcaatttac tattttggat gttcctgcat acgccattga caattatcca gcgcagaggt
     1321 cacgaagtaa aggagtttcc agagccaaac agtgacgaga ttaaaggggt ggatgcaacc
     1381 atttcagagg gctggattga tttaaaagtg cgaaacgata ccgactgcac ctaccaaata
     1441 tgggtgacct tagatgatga gaaaatcatc ggtcaggtgt tcgccgacaa agagccccaa
     1501 gcattataca aaattacaaa tggcagtatc cagtatgtcc gtgaaagtgg cgggatttat
     1561 gaatatgccc aggttaaacg gatgcaagtt gccttaggta ccggggaaat aatagattgc
     1621 aagctgcttt atacaaacaa atgcaaaatc tgttatcccc tcccggaaag tgtggatatt
     1681 caggaggaga accaatgaga aaaagtgtgg gcattactgt ttttggatgc gaacaggatg
     1741 aggcaaatgc tttccgcgc
//
LOCUS       DBBGSP010000225          992 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.guided.184, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000225 DBBGSP010000000
VERSION     DBBGSP010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.guided.184"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            complement(39..341)
                     /locus_tag="ACIZE9_003276"
                     /pseudo
     CDS             complement(39..341)
                     /locus_tag="ACIZE9_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
     gene            434..783
                     /locus_tag="ACIZE9_003277"
                     /pseudo
     CDS             434..783
                     /locus_tag="ACIZE9_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
BASE COUNT          335 a          179 c          135 g          343 t
ORIGIN      
        1 atggattttt tcatttacac aaaatatttt atactctcaa catacttgca aagtaatact
       61 acaattccta acataatcgt agaatttaat aatttccata gcataaagtg tttagaaaag
      121 aacattaaga atagttctat aataattctt gaactccatg tcttataatg ttctatcgaa
      181 gcacccaaat agccaagttc atctaatcta cttgcataaa ctacgtcatc cgctctcata
      241 gtcggcatat acatattaaa gagtaaaaag ataccccaaa tccctattag taacaagatc
      301 agttctttgt tattcgttat ttttctatta tgtttgttca tttttatact ccttcttata
      361 tttcctaata gagtataaca tagctttaag cattacttaa agataactta aaagttatct
      421 tttaaatact taattgttaa ataccttatt tgatgcaaaa gaaatctacg atagtcaaca
      481 aaaaaatttt cattatatcc agaaaaattt ttcttagtta aggacctatg gattgcagta
      541 atgcagaatt cgtcgaataa actgccaaag acatacaatc atattgcttt taaaattgac
      601 gaacaagata tagattcgtt tgtctcaaaa atccaaatgt taggtttaac tgtcgaacca
      661 ggacgttctc gtgtgaaagg cgaggcttct tcaatttact tttacgacta tgataatcac
      721 ctcttcgagt tacataccgg tactctccag gaacgtttaa aatcctacaa ttccactacc
      781 tgagactagt aatgactagt ctctttttat ggcctctgat ccccccattg agcgaatact
      841 aatagggctt cgaattgatc tgttcaatct ttaagcaata tccctcaaat gagtttggaa
      901 agtttagtga ttcatcacaa atacttaaat acatgtagtt atatatagat tgaggttctt
      961 gtgagcgtat gctcgtgtgg gttcaaatcc ca
//
LOCUS       DBBGSP010000226          817 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345633-rid23690363.guided.187, whole genome shotgun
            sequence.
ACCESSION   DBBGSP010000226 DBBGSP010000000
VERSION     DBBGSP010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345633
            Sequence Read Archive: ERR12710972
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429597.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429597.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:24:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,278
            CDSs (total)                      :: 3,217
            Genes (coding)                    :: 3,138
            CDSs (with protein)               :: 3,138
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 34 of 79
            Pseudo Genes (incomplete)         :: 39 of 79
            Pseudo Genes (internal stop)      :: 24 of 79
            Pseudo Genes (multiple problems)  :: 15 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..817
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345633-rid23690363.guided.187"
                     /isolate="clinical isolate"
                     /isolation_source="Urin Mittelstrahl"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="2020-02-24"
     gene            204..752
                     /gene="aac(6')"
                     /locus_tag="ACIZE9_003278"
     CDS             204..752
                     /gene="aac(6')"
                     /locus_tag="ACIZE9_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HGC6095041.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          290 a          123 c          176 g          228 t
ORIGIN      
        1 caaacagagt tttttcctcc aattgatggc tttcctgatc tttcctattt tgaataaagt
       61 gtttctgtat aattttttat tttataagta agataaataa tgaaagaata gagatactga
      121 ttggtagcta aagatttttg agcgagaaca tttcgttttt tcaaaaggac tgttagaata
      181 agcaagaaca agggggaaga cgtatgataa tcagtgaatt tgaccgtaat aatccagtat
      241 tgaaagatca gctttctgat ttactgagac tgacttggcc ggaagaatat ggagacagct
      301 cggcagaaga agtagaagaa atgatgaatc cagaacgaat cgcggtagca gcggtagacc
      361 aagatgagtt agtaggattt attggtgcaa tccctcaata cggtatcaca ggttgggaat
      421 tgcatccatt agttgtagaa agctcccgac gaaagaacca aataggtact cgattagtca
      481 attacttaga aaaagaagta gcttccagag gaggaatcac gatttattta ggtacggatg
      541 atttagacca tggaacaacg ttaagtcaaa cggacctgta tgagcataca tttgataaag
      601 tggcttccat ccagaacctt cgtgaacatc cgtatgaatt ctatgaaaaa ttaggttata
      661 aaatcgtagg tgtcttacca aatgcaaatg gctgggacaa accggatatt tggatggcaa
      721 aaacgattat tcctcgacca aattctcaat aataaaaaga ggttgtgaca gaagtaatca
      781 gcttcaagaa ataagaagga atttacgaaa attactt
//
